Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000783-TA|BGIBMGA000783-PA|IPR000152|Aspartic acid and
asparagine hydroxylation site, IPR013032|EGF-like region,
IPR001881|EGF-like calcium-binding, IPR001774|Delta/Serrate/lag-2
(DSL) protein, IPR006210|EGF, IPR009041|Proteinase inhibitor, PMP and
SGCI, IPR009030|Growth factor, receptor, IPR000742|EGF-like, type 3,
IPR001438|EGF-like, type 2, IPR011651|Notch ligand, N-terminal,
IPR013111|EGF, extracellular, IPR006209|EGF-like, IPR013091|EGF
calcium-binding
(996 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 602 e-171
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 602 e-171
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 602 e-171
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 602 e-171
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 602 e-171
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 602 e-171
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 602 e-171
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 602 e-171
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 600 e-170
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 576 e-163
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 576 e-163
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 575 e-163
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 575 e-163
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 573 e-162
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 506 e-142
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 423 e-117
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 423 e-117
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 423 e-117
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 423 e-117
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 420 e-116
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 420 e-116
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 420 e-116
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 420 e-116
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 420 e-116
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 420 e-116
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 415 e-115
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 311 7e-84
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 311 7e-84
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 311 7e-84
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 307 1e-82
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 307 1e-82
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 307 1e-82
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 307 1e-82
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 303 1e-81
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 303 1e-81
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 295 7e-79
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 293 2e-78
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 293 2e-78
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 293 2e-78
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 293 2e-78
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 293 2e-78
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 272 4e-72
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 272 4e-72
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 272 4e-72
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 272 4e-72
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 272 4e-72
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 272 4e-72
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 270 1e-71
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 270 1e-71
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 270 1e-71
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 261 1e-68
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 250 2e-65
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 234 1e-60
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 233 3e-60
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 228 9e-59
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 228 9e-59
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 228 9e-59
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 228 9e-59
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 228 9e-59
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 227 2e-58
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 227 2e-58
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 227 2e-58
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 227 2e-58
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 227 2e-58
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 227 2e-58
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 213 2e-54
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 212 5e-54
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 212 6e-54
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 212 6e-54
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 212 6e-54
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 208 6e-53
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 208 6e-53
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 206 2e-52
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 204 1e-51
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 204 1e-51
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 204 1e-51
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 204 1e-51
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 204 1e-51
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 204 1e-51
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 192 7e-48
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 191 1e-47
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 189 5e-47
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 189 5e-47
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 189 5e-47
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 188 1e-46
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 188 1e-46
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 188 1e-46
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 188 1e-46
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 180 2e-44
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 173 3e-42
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 171 8e-42
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 171 8e-42
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 171 8e-42
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 171 8e-42
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 170 2e-41
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 168 7e-41
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 168 7e-41
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 168 7e-41
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 168 7e-41
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 168 7e-41
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 167 2e-40
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 167 2e-40
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 167 2e-40
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 167 2e-40
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 167 2e-40
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 167 2e-40
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 166 3e-40
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 163 3e-39
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 162 5e-39
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 158 1e-37
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 154 2e-36
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 153 4e-36
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 153 4e-36
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 151 9e-36
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 151 2e-35
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 150 3e-35
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 150 3e-35
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 149 4e-35
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 149 4e-35
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 149 4e-35
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 149 6e-35
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 146 3e-34
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 145 6e-34
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 144 1e-33
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 144 1e-33
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 144 1e-33
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 143 3e-33
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 143 3e-33
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 143 3e-33
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 143 3e-33
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 143 3e-33
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 143 3e-33
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 143 3e-33
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 143 3e-33
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 143 3e-33
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 143 3e-33
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 143 3e-33
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 143 3e-33
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 136 3e-31
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 136 3e-31
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 136 3e-31
AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens ... 136 3e-31
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 136 3e-31
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 136 4e-31
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 136 5e-31
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 136 5e-31
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 135 8e-31
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 135 8e-31
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 135 8e-31
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 135 8e-31
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 134 1e-30
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 133 3e-30
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 132 5e-30
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 132 6e-30
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 131 1e-29
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 130 2e-29
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 129 6e-29
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 129 6e-29
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 129 6e-29
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 129 6e-29
AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 128 1e-28
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 127 2e-28
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 127 2e-28
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 127 2e-28
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 126 3e-28
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 126 5e-28
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 126 5e-28
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 125 7e-28
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 125 7e-28
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 125 9e-28
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 124 1e-27
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 124 1e-27
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 124 1e-27
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 124 1e-27
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 124 1e-27
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 124 1e-27
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 124 2e-27
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 124 2e-27
AL359813-7|CAI23222.1| 134|Homo sapiens EGF-like-domain, multip... 123 4e-27
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 122 6e-27
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 122 6e-27
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 122 8e-27
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 122 8e-27
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 122 8e-27
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 120 2e-26
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 120 3e-26
Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 119 6e-26
Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 119 6e-26
Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 119 6e-26
AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 119 6e-26
AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 119 6e-26
AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 119 6e-26
AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein. 119 6e-26
AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein. 118 8e-26
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 114 2e-24
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 114 2e-24
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 114 2e-24
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 114 2e-24
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 114 2e-24
BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 112 7e-24
AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multip... 112 7e-24
AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multip... 112 7e-24
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 111 1e-23
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 111 1e-23
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 109 6e-23
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 108 1e-22
AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein. 107 2e-22
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 106 3e-22
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 106 4e-22
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 106 4e-22
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 105 8e-22
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 105 8e-22
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 105 8e-22
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 105 8e-22
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 105 8e-22
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 104 2e-21
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 103 3e-21
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 103 3e-21
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 103 3e-21
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 103 3e-21
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 103 4e-21
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 103 4e-21
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 100 2e-20
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 100 3e-20
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 98 2e-19
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 98 2e-19
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 98 2e-19
AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein. 97 4e-19
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 96 5e-19
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 96 5e-19
AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type... 96 6e-19
AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein. 96 6e-19
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 95 1e-18
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 95 1e-18
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 95 1e-18
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 95 1e-18
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 95 1e-18
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 95 1e-18
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 95 1e-18
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 94 2e-18
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 93 4e-18
AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein. 93 4e-18
AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein. 93 4e-18
AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein. 93 4e-18
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 91 2e-17
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 91 2e-17
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 91 2e-17
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 91 2e-17
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 91 2e-17
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 90 3e-17
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 90 3e-17
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 90 3e-17
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 90 3e-17
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 90 3e-17
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 90 3e-17
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 90 3e-17
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 90 3e-17
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 90 3e-17
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 90 3e-17
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 90 3e-17
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 90 4e-17
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 90 4e-17
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 90 4e-17
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 90 4e-17
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 89 6e-17
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 89 7e-17
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 89 1e-16
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 89 1e-16
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein. 88 1e-16
BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein. 88 1e-16
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 88 1e-16
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 88 1e-16
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 88 1e-16
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 88 2e-16
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 88 2e-16
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 88 2e-16
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 88 2e-16
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 88 2e-16
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 88 2e-16
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 88 2e-16
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 88 2e-16
AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. 87 2e-16
AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p... 87 2e-16
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 87 3e-16
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 87 3e-16
BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 87 4e-16
AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 87 4e-16
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 87 4e-16
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 87 4e-16
AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 87 4e-16
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 87 4e-16
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 86 5e-16
M24630-1|AAA52703.1| 1625|Homo sapiens hexabrachion protein. 86 5e-16
AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS... 86 7e-16
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 85 9e-16
BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. 85 9e-16
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 85 2e-15
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 84 2e-15
D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 84 2e-15
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 84 2e-15
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 84 2e-15
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 84 3e-15
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 84 3e-15
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 84 3e-15
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 83 5e-15
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 83 5e-15
J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 83 5e-15
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 83 5e-15
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 83 5e-15
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 83 5e-15
S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protei... 83 6e-15
D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protei... 83 6e-15
BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding prot... 83 6e-15
AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding prot... 83 6e-15
AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding prot... 83 6e-15
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 82 8e-15
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 82 8e-15
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein. 82 8e-15
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 82 8e-15
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 82 8e-15
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr... 82 8e-15
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 82 8e-15
AB067494-1|BAB67800.1| 1737|Homo sapiens KIAA1907 protein protein. 82 8e-15
AB024578-1|BAA88952.1| 78|Homo sapiens notch4 protein. 82 8e-15
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 81 1e-14
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 81 1e-14
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 80 3e-14
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 80 3e-14
U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein ... 80 4e-14
BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and di... 80 4e-14
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 80 4e-14
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 80 4e-14
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 79 8e-14
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 79 1e-13
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 79 1e-13
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 79 1e-13
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 79 1e-13
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 78 1e-13
AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens ... 78 1e-13
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 78 1e-13
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 78 2e-13
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 78 2e-13
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 78 2e-13
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 78 2e-13
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 78 2e-13
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 78 2e-13
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 78 2e-13
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 78 2e-13
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 77 2e-13
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 77 2e-13
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 77 2e-13
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 77 2e-13
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 77 3e-13
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 77 4e-13
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 76 5e-13
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 76 5e-13
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 76 5e-13
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 76 5e-13
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 76 5e-13
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 76 5e-13
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 76 5e-13
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 1e-12
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 1e-12
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 1e-12
AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein. 75 1e-12
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 75 1e-12
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 74 3e-12
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 73 5e-12
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 73 5e-12
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 73 5e-12
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 73 5e-12
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 73 7e-12
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 73 7e-12
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 72 9e-12
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 72 9e-12
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 72 9e-12
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 72 9e-12
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 72 1e-11
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 72 1e-11
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 72 1e-11
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 72 1e-11
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 71 2e-11
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 71 2e-11
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 71 2e-11
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 71 2e-11
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 71 2e-11
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 71 2e-11
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 71 2e-11
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr... 71 2e-11
S77512-1|AAB34682.2| 1798|Homo sapiens laminin beta 2 chain prot... 71 3e-11
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr... 71 3e-11
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p... 71 3e-11
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f... 71 3e-11
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ... 71 3e-11
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 71 3e-11
Z68155-1|CAA92279.1| 1798|Homo sapiens laminin beta 2 chain prot... 70 4e-11
U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein ... 70 4e-11
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 70 4e-11
BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. 70 5e-11
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 70 5e-11
AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant... 70 5e-11
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 70 5e-11
AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. 70 5e-11
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr... 69 6e-11
AL355357-1|CAI16435.1| 95|Homo sapiens protein ( Human DNA seq... 69 6e-11
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 69 8e-11
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 69 1e-10
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 69 1e-10
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 69 1e-10
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 67 3e-10
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 67 3e-10
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 67 3e-10
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 67 3e-10
AF283412-1|AAL38110.1| 172|Homo sapiens candidate tumor suppres... 67 3e-10
AF193046-1|AAG22474.1| 277|Homo sapiens unknown protein. 67 3e-10
AC092156-1|AAY15024.1| 330|Homo sapiens unknown protein. 67 3e-10
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 66 4e-10
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 66 4e-10
D50030-1|BAA74450.1| 655|Homo sapiens hepatocyte growth factor ... 66 4e-10
D14012-1|BAA03113.1| 655|Homo sapiens HGF activator precursor p... 66 4e-10
BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 66 4e-10
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 66 4e-10
AL590235-6|CAM21456.1| 655|Homo sapiens HGF activator protein. 66 4e-10
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 66 4e-10
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 66 4e-10
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 66 4e-10
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 66 6e-10
X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein. 65 1e-09
AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein. 65 1e-09
BC112192-1|AAI12193.1| 655|Homo sapiens HGF activator, prepropr... 65 1e-09
BC112190-1|AAI12191.1| 655|Homo sapiens HGF activator, prepropr... 65 1e-09
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 65 1e-09
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 65 1e-09
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 64 2e-09
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 64 2e-09
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 64 2e-09
AB177801-1|BAD16737.1| 195|Homo sapiens fibrillin 1 protein. 64 2e-09
M31315-1|AAA70225.1| 612|Homo sapiens F12 protein. 62 7e-09
M17466-1|AAB59490.1| 615|Homo sapiens coagulation factor XII pr... 62 7e-09
M11723-1|AAA51986.1| 602|Homo sapiens F12 protein. 62 7e-09
AF538691-1|AAM97932.1| 615|Homo sapiens coagulation factor XII ... 62 7e-09
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 62 7e-09
AB095845-1|BAC23095.1| 615|Homo sapiens coagulation factor XII-... 62 7e-09
Z94057-1|CAI21650.1| 1358|Homo sapiens tenascin R (restrictin, j... 62 1e-08
Z94055-1|CAI19943.1| 1358|Homo sapiens tenascin R (restrictin, j... 62 1e-08
Z67996-1|CAA91947.1| 1358|Homo sapiens tenascin-R (restrictin) p... 62 1e-08
X98085-1|CAA66709.1| 1358|Homo sapiens tenascin-R protein. 62 1e-08
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 62 1e-08
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein. 62 1e-08
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein. 62 1e-08
M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. 62 1e-08
M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. 62 1e-08
M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. 62 1e-08
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein. 62 1e-08
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 62 1e-08
BC129830-1|AAI29831.1| 1257|Homo sapiens TNR protein protein. 62 1e-08
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein. 62 1e-08
BC074907-1|AAH74907.1| 400|Homo sapiens protein Z, vitamin K-de... 62 1e-08
BC074906-1|AAH74906.1| 400|Homo sapiens protein Z, vitamin K-de... 62 1e-08
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein. 62 1e-08
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 62 1e-08
AL137002-16|CAI41389.1| 422|Homo sapiens protein Z, vitamin K-d... 62 1e-08
AL137002-15|CAI41388.1| 400|Homo sapiens protein Z, vitamin K-d... 62 1e-08
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 62 1e-08
AF440358-1|AAL27631.1| 400|Homo sapiens protein Z, vitamin K-de... 62 1e-08
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 62 1e-08
AB033749-2|BAA85764.1| 422|Homo sapiens protein Z spliced varia... 62 1e-08
AB033749-1|BAA85763.1| 400|Homo sapiens protein Z protein. 62 1e-08
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 62 1e-08
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 62 1e-08
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 61 2e-08
M13232-2|AAA88041.1| 444|Homo sapiens protein ( Human factor VI... 61 2e-08
M13232-1|AAA88040.1| 466|Homo sapiens coagulation factor VII pr... 61 2e-08
J02933-1|AAA51983.1| 466|Homo sapiens protein ( Human blood coa... 61 2e-08
DQ142911-1|ABD17891.1| 466|Homo sapiens cogulation factor VII p... 61 2e-08
BC130468-1|AAI30469.1| 444|Homo sapiens coagulation factor VII ... 61 2e-08
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 61 2e-08
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 61 2e-08
AY212252-1|AAP33841.1| 466|Homo sapiens FVII coagulation protei... 61 2e-08
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 61 2e-08
AL137002-10|CAI41381.1| 466|Homo sapiens coagulation factor VII... 61 2e-08
AL137002-9|CAI41382.1| 444|Homo sapiens coagulation factor VII ... 61 2e-08
AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein. 61 2e-08
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 14 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 71
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 72 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 131
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 132 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 191
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 192 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 251
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 252 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 310
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 311 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 369
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 370 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 421
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 422 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 481
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 482 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 541
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 542 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 598
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 599 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 656
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 657 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 694
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 270 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 329
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 330 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 387
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 388 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 444
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 445 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 503
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 504 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 555
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 556 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 615
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 616 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 675
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 676 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 721
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 722 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 776
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 777 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 830
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 831 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 862
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 863 WDDDCNTCQCLNGRIACSKVWCGPRPCL 890
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 618 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 675
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 676 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 733
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 734 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 791
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 792 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 843
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 844 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 903
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 904 CIPILDDQCFVHPCTGVGEC 923
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIRDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIRDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 602 bits (1487), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 602 bits (1486), Expect = e-171
Identities = 273/698 (39%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDPNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC NGG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (705), Expect = 1e-76
Identities = 193/688 (28%), Positives = 270/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL+G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 600 bits (1481), Expect = e-170
Identities = 272/698 (38%), Positives = 365/698 (52%), Gaps = 34/698 (4%)
Query: 7 KFCAAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQS 66
K C A +G FEL+IL N E+ C T F +CLKEYQS
Sbjct: 27 KVCGA-SGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDE-CDTYFKVCLKEYQS 84
Query: 67 AAAPGGSCSFGRAASPVLGTDSFTL----AEPLYTLALPFSFRWTRSFTLILQAYDDYEY 122
GG CSFG ++PV+G ++F L + LPFSF W RS+TL+++A+D
Sbjct: 85 RVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSND 144
Query: 123 SEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCRPRD 182
+ +IE+A SG++ PS +W C YY C FCRPRD
Sbjct: 145 TVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRD 204
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ 242
D FGHY+C +G+K C+ GW G C + +C++GC P HG C PGDC C+ GW+G C +
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK 264
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C P+PGC HG CN W C C+TNWGG LCD+DLNYCGTH+PC +GGTC NT PD+Y C
Sbjct: 265 CIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C EG+SG +CE ++ C PC H S T+ GF C C GW G +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPC-HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C HG +C+D ++GF C C WTG C D +EC + PCVNA +C N Y
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--------PCVNAKSCKNLIASY 434
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C CL GW G++C+ N++DC GQC + A+C DLV+ + C C GYAG C D+D+CA
Sbjct: 435 YCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN 494
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC +GG C + +N ++C+CP GFSG C+ D D+C +PC NGA CY SDY+C C
Sbjct: 495 PCLDGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 543 WTGKNCTQRAARDRKT-------CSVLVEESER------CAEGMCANGGTCVREEGSWRX 589
+ GKNC+ R T C+V + ++ + +C G C + G
Sbjct: 555 YEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG--- 611
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ + GGTC+ + C C +G GA CE +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNIN 669
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +PC NGG C + C+C GW G+TC R S
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 287 bits (703), Expect = 2e-76
Identities = 193/688 (28%), Positives = 269/688 (39%), Gaps = 117/688 (17%)
Query: 164 LCQPNYYNTTCT---TFCRPRDDKFGHYSCTPDG-DKH---CLPGWQGDNCE--KPVC-K 213
LC+ N+ C +C +C+ G DK+ C G+ G NCE + C
Sbjct: 283 LCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLS 342
Query: 214 EGCHPTHGRCDRPG---DCDCRPGWRGELCS----QCQPYPGCKHG-YCNG--SSWDCTC 263
+ CH G C +C+C PGW G CS C P C HG C + + C C
Sbjct: 343 DPCH-NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN-NCSHGGTCQDLVNGFKCVC 400
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP 323
W G C D N C +PC + +C+N Y+C C G+ G +C+ N C Q
Sbjct: 401 PPQWTGKTCQLDANECEA-KPCVNAKSCKNLIAS-YYCDCLPGWMGQNCDININDCLGQ- 457
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADG 383
S G+ C C G+ G AS PCL G C++ ++ F C C G
Sbjct: 458 -CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTG 516
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------- 436
++G C D+D C PC N A C N A Y C C + G++C
Sbjct: 517 FSGNLCQLDIDYCEPN--------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 437 ----TNVDDCT-----------------GQC-LHGATCIDLVDDFHCACAAGYAGRTCSL 474
+D CT C HG F C C G+ G C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+++DC PC NGG C+D +N+Y+CIC G+ G CE + + C+ +PC NG C +D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+YC C GW GK C R +C E C NGGTC E +++
Sbjct: 689 FYCDCKNGWKGKTCHSR--------------DSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ GGTC+ + + C C+EG G +C + + C
Sbjct: 735 WEGTTCN---IARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTR 714
PC N G CV G W+ CEC G+ G C + ++ + R
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININ------ECQSSPCAFGATCVDEINGYR 843
Query: 715 CLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTW 774
C+C PP + +C E V RP +G + +G
Sbjct: 844 CVC--PPGHSGAKCQE---------------------VSGRPCITMGS-----VIPDGAK 875
Query: 775 W-WGCNACWCSGGVPTCTRLWCGLPDCL 801
W CN C C G C+++WCG CL
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Score = 135 bits (326), Expect = 8e-31
Identities = 96/320 (30%), Positives = 129/320 (40%), Gaps = 48/320 (15%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SS 258
++CE C+ G G C C GW G C + C P G C +
Sbjct: 631 NDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNP 318
+ C C W G C + C C +GGTC + D + C C G+ G C N
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEG-DAFKCMCPGGWEGTTCNIARNS 746
Query: 319 -CAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C P PC +G TC + G + FTC C GW G + PC + +C D + +
Sbjct: 747 SCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 804
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CECA G+ GP C +++EC PC A C + GY C C G +G C+
Sbjct: 805 RCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Query: 437 T----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGYA----GRT 471
+V DDC T QCL+G V C G++ G++
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Query: 472 CSLDVDD-CAPRPCTNGGEC 490
C +DD C PCT GEC
Sbjct: 917 CIPILDDQCFVHPCTGVGEC 936
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 576 bits (1423), Expect = e-163
Identities = 276/700 (39%), Positives = 351/700 (50%), Gaps = 43/700 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 28 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 87
Query: 74 CSFGRAASPVLGTDSFTL-----------AEPLYT-------LALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L A P + +PF F W RSFTLI++
Sbjct: 88 CSYGHGATPVLGGNSFYLPPAGAAGDRARARPRAGGDQDPGFVVIPFQFAWPRSFTLIVE 147
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 148 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 207
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 267
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 268 WQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCALD 385
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
AS PC G +C D +DGF C C + W G C DV++C G+ PC+NA +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCEGK--------PCLNAFS 437
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C N GGY C C+ GW G +C NV+DC GQC HG TC DLV+ + C C G+ GR C L
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCEL 497
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+ D CA PC +GG C DL + + C CP GFSG CE D D C SPC NGA CY + D
Sbjct: 498 ERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 557
Query: 535 YYCHCAPGWTGKNCT-QRAARDRKTCSVL--------VEESERCAEGMCANGGTCVREEG 585
YYC C + GKNC+ R C V+ A G+C G CV + G
Sbjct: 558 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 617
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
+ + GGTC+ + C C G G LC+
Sbjct: 618 G---NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV--DAFRCFCPSGWEGELCD 672
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
+ + C PC + GRC + C C GW G+TC R
Sbjct: 673 TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 296 bits (726), Expect = 3e-79
Identities = 192/642 (29%), Positives = 258/642 (40%), Gaps = 102/642 (15%)
Query: 198 CLPGWQGDNCEKP--VCKEGCHPTHGRCDR-PG--DCDCRPGWRGELCS----QCQPYPG 248
C G+ G NCEK C G C P +C C GW G C+ +C P
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C ++C C W G C D+N C +PC + +C+N Y+C C G
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDVNDC-EGKPCLNAFSCKNLIGG-YYCDCIPG 452
Query: 307 FSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
+ G++C N C Q C HG TC G+ C C RG+GG AS PC
Sbjct: 453 WKGINCHINVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCELERDKCASSPCHS 509
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C D DGF C C G++GP C DVD C PC N A C N G Y CA
Sbjct: 510 GGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNGARCYNLEGDYYCA 561
Query: 426 CLAGWTGRDCETN-----------VDDC-------------TGQC-LHGATCIDLVDDFH 460
C + G++C +D C +G C HG +F
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G C+ + + C
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + CY +D+YC C GW GK C R + C C+NGGTC
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ--------------CDAYTCSNGGTC 727
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
++R + GGTC+ S ++C CR+G
Sbjct: 728 YDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA--SFSCICRDGWE 782
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXX 700
G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID------ECQSSPC 836
Query: 701 XXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNV 760
+ RC C PP RA RC E + ++R P
Sbjct: 837 AYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------GFGRSCWSRGTP-- 878
Query: 761 GDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
+G+ W CN+C C G C+++WCG CL
Sbjct: 879 --------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 912
Score = 264 bits (647), Expect = 1e-69
Identities = 169/561 (30%), Positives = 224/561 (39%), Gaps = 69/561 (12%)
Query: 166 QPNYYNTTCTTFCRPRDDKFGHYSCT-------------PDG-DKHCLPGWQGDNCEKPV 211
+P+ Y TC R+ + ++CT P G + HC GW G C +
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 212 CKEGCHP--THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWD 260
+ +P G C D C C W G C + C+ P C +
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCEGKPCLNAFSCKNLIGGYY 446
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C W GI C ++N C CQHGGTC++ + Y C C GF G CE + CA
Sbjct: 447 CDCIPGWKGINCHINVNDC--RGQCQHGGTCKDLV-NGYQCVCPRGFGGRHCELERDKCA 503
Query: 321 PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE 379
PC + G C GF C C +G+ G PC +GA C + + C
Sbjct: 504 SSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCA 561
Query: 380 CADGWTGPACAEDVDECSGRS--MTEG-------------ALGPCVNAAACNNTAGG-YS 423
C D + G C+ + C G + + +G A G C C + GG +S
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C +G+TG C N+DDC GQ C +G TCID VD F C C +G+ G C + +DC P
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC + G C DL+N + C C G+ G C C C NG CY + + C C PG
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
W G C V ++ C C NGGTCV S+
Sbjct: 742 WKGSTCA-------------VAKNSSCLPNPCVNGGTCVGSGASF----SCICRDGWEGR 784
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGW-ACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG C+ W C C G G C +++D C SSPC G
Sbjct: 785 TCTHNTNDCNPLPCYNGGICVDGV---NWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 841
Query: 662 CVGGSGWWMCECVAGWTGETC 682
CV + C C G G C
Sbjct: 842 CVDEINGYRCSCPPGRAGPRC 862
Score = 66.9 bits (156), Expect = 3e-10
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ +A P + C C +G +G CE + C S+PC NGG C + C C +GW+
Sbjct: 320 GGTCI-NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 679 GETCAVRV 686
G TCA+ +
Sbjct: 379 GPTCALDI 386
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 576 bits (1422), Expect = e-163
Identities = 274/700 (39%), Positives = 350/700 (50%), Gaps = 43/700 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 28 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 87
Query: 74 CSFGRAASPVLGTDSFTLA------------------EPLYTLALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L + + +PF F W RSFTLI++
Sbjct: 88 CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVE 147
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 148 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 207
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 267
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 268 WQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCALD 385
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
AS PC G +C D +DGF C C + W G C D +EC G+ PC+NA +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK--------PCLNAFS 437
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C N GGY C C+ GW G +C NV+DC GQC HG TC DLV+ + C C G+ GR C L
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCEL 497
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+ D+CA PC +GG C DL + + C CP GFSG CE D D C SPC NGA CY + D
Sbjct: 498 ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 557
Query: 535 YYCHCAPGWTGKNCT-QRAARDRKTCSVL--------VEESERCAEGMCANGGTCVREEG 585
YYC C + GKNC+ R C V+ A G+C G CV + G
Sbjct: 558 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 617
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
+ + GGTC+ + C C G G LC+
Sbjct: 618 G---NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV--DAFRCFCPSGWEGELCD 672
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
+ + C PC + GRC + C C GW G+TC R
Sbjct: 673 TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 295 bits (725), Expect = 4e-79
Identities = 192/642 (29%), Positives = 257/642 (40%), Gaps = 102/642 (15%)
Query: 198 CLPGWQGDNCEKP--VCKEGCHPTHGRCDR-PG--DCDCRPGWRGELCS----QCQPYPG 248
C G+ G NCEK C G C P +C C GW G C+ +C P
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C ++C C W G C D N C +PC + +C+N Y+C C G
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDANEC-EGKPCLNAFSCKNLIGG-YYCDCIPG 452
Query: 307 FSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
+ G++C N C Q C HG TC G+ C C RG+GG AS PC
Sbjct: 453 WKGINCHINVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCELERDECASSPCHS 509
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C D DGF C C G++GP C DVD C PC N A C N G Y CA
Sbjct: 510 GGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNGARCYNLEGDYYCA 561
Query: 426 CLAGWTGRDCETN-----------VDDC-------------TGQC-LHGATCIDLVDDFH 460
C + G++C +D C +G C HG +F
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G C+ + + C
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + CY +D+YC C GW GK C R + C C+NGGTC
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ--------------CDAYTCSNGGTC 727
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
++R + GGTC+ S ++C CR+G
Sbjct: 728 YDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA--SFSCICRDGWE 782
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXX 700
G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID------ECQSSPC 836
Query: 701 XXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNV 760
+ RC C PP RA RC E + ++R P
Sbjct: 837 AYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------GFGRSCWSRGTP-- 878
Query: 761 GDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
+G+ W CN+C C G C+++WCG CL
Sbjct: 879 --------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 912
Score = 265 bits (649), Expect = 6e-70
Identities = 169/561 (30%), Positives = 225/561 (40%), Gaps = 69/561 (12%)
Query: 166 QPNYYNTTCTTFCRPRDDKFGHYSCT-------------PDG-DKHCLPGWQGDNCEKPV 211
+P+ Y TC R+ + ++CT P G + HC GW G C +
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 212 CKEGCHP--THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWD 260
+ +P G C D C C W G C ++C+ P C +
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYY 446
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C W GI C ++N C CQHGGTC++ + Y C C GF G CE + CA
Sbjct: 447 CDCIPGWKGINCHINVNDC--RGQCQHGGTCKDLV-NGYQCVCPRGFGGRHCELERDECA 503
Query: 321 PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE 379
PC + G C GF C C +G+ G PC +GA C + + C
Sbjct: 504 SSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCA 561
Query: 380 CADGWTGPACAEDVDECSGRS--MTEG-------------ALGPCVNAAACNNTAGG-YS 423
C D + G C+ + C G + + +G A G C C + GG +S
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C +G+TG C N+DDC GQ C +G TCID VD F C C +G+ G C + +DC P
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC + G C DL+N + C C G+ G C C C NG CY + + C C PG
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
W G C V ++ C C NGGTCV S+
Sbjct: 742 WKGSTCA-------------VAKNSSCLPNPCVNGGTCVGSGASF----SCICRDGWEGR 784
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGW-ACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG C+ W C C G G C +++D C SSPC G
Sbjct: 785 TCTHNTNDCNPLPCYNGGICVDGV---NWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 841
Query: 662 CVGGSGWWMCECVAGWTGETC 682
CV + C C G G C
Sbjct: 842 CVDEINGYRCSCPPGRAGPRC 862
Score = 204 bits (498), Expect = 1e-51
Identities = 118/362 (32%), Positives = 150/362 (41%), Gaps = 28/362 (7%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKH 251
HC G+ G CE V C+ RC + GD C C + G+ CS P C
Sbjct: 523 HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV--PREPCPG 580
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C C D G+ CG H G C + + C C GF+G
Sbjct: 581 GACRVID-GCGSDAG-PGMPGTAASGVCGPH------GRCVSQPGGNFSCICDSGFTGTY 632
Query: 312 CERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR 370
C + C QPC +G TC F C C GW G PC C
Sbjct: 633 CHENIDDCLGQPCRNGGTC--IDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 690
Query: 371 DHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
D ++ F C C DGW G C +C + C N C ++ + CAC GW
Sbjct: 691 DLVNDFYCACDDGWKGKTCHSREFQCDAYT--------CSNGGTCYDSGDTFRCACPPGW 742
Query: 431 TGRDCET--NVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
G C N C++G TC+ F C C G+ GRTC+ + +DC P PC NGG
Sbjct: 743 KGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGG 802
Query: 489 ECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
CVD +N +RC C GF+G +C + D C SPC GA C + Y C C PG G C
Sbjct: 803 ICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Query: 549 TQ 550
+
Sbjct: 863 QE 864
Score = 66.9 bits (156), Expect = 3e-10
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ +A P + C C +G +G CE + C S+PC NGG C + C C +GW+
Sbjct: 320 GGTCI-NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 679 GETCAVRV 686
G TCA+ +
Sbjct: 379 GPTCALDI 386
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 575 bits (1419), Expect = e-163
Identities = 274/700 (39%), Positives = 349/700 (49%), Gaps = 43/700 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 28 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 87
Query: 74 CSFGRAASPVLGTDSFTLA------------------EPLYTLALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L + + +PF F W RSFTLI++
Sbjct: 88 CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVE 147
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 148 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 207
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 267
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 268 WQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCALD 385
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
AS PC G +C D +DGF C C + W G C D +EC G+ PC+NA +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK--------PCLNAFS 437
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C N GGY C C+ GW G +C NV+DC GQC HG TC DLV+ + C C G+ GR C L
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCEL 497
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+ D CA PC +GG C DL + + C CP GFSG CE D D C SPC NGA CY + D
Sbjct: 498 ERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 557
Query: 535 YYCHCAPGWTGKNCT-QRAARDRKTCSVL--------VEESERCAEGMCANGGTCVREEG 585
YYC C + GKNC+ R C V+ A G+C G CV + G
Sbjct: 558 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 617
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
+ + GGTC+ + C C G G LC+
Sbjct: 618 G---NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV--DAFRCFCPSGWEGELCD 672
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
+ + C PC + GRC + C C GW G+TC R
Sbjct: 673 TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 295 bits (725), Expect = 4e-79
Identities = 192/642 (29%), Positives = 257/642 (40%), Gaps = 102/642 (15%)
Query: 198 CLPGWQGDNCEKP--VCKEGCHPTHGRCDR-PG--DCDCRPGWRGELCS----QCQPYPG 248
C G+ G NCEK C G C P +C C GW G C+ +C P
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C ++C C W G C D N C +PC + +C+N Y+C C G
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDANEC-EGKPCLNAFSCKNLIGG-YYCDCIPG 452
Query: 307 FSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
+ G++C N C Q C HG TC G+ C C RG+GG AS PC
Sbjct: 453 WKGINCHINVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCELERDKCASSPCHS 509
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C D DGF C C G++GP C DVD C PC N A C N G Y CA
Sbjct: 510 GGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNGARCYNLEGDYYCA 561
Query: 426 CLAGWTGRDCETN-----------VDDC-------------TGQC-LHGATCIDLVDDFH 460
C + G++C +D C +G C HG +F
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G C+ + + C
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + CY +D+YC C GW GK C R + C C+NGGTC
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ--------------CDAYTCSNGGTC 727
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
++R + GGTC+ S ++C CR+G
Sbjct: 728 YDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA--SFSCICRDGWE 782
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXX 700
G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID------ECQSSPC 836
Query: 701 XXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNV 760
+ RC C PP RA RC E + ++R P
Sbjct: 837 AYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------GFGRSCWSRGTP-- 878
Query: 761 GDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
+G+ W CN+C C G C+++WCG CL
Sbjct: 879 --------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 912
Score = 265 bits (649), Expect = 6e-70
Identities = 169/561 (30%), Positives = 225/561 (40%), Gaps = 69/561 (12%)
Query: 166 QPNYYNTTCTTFCRPRDDKFGHYSCT-------------PDG-DKHCLPGWQGDNCEKPV 211
+P+ Y TC R+ + ++CT P G + HC GW G C +
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 212 CKEGCHP--THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWD 260
+ +P G C D C C W G C ++C+ P C +
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYY 446
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C W GI C ++N C CQHGGTC++ + Y C C GF G CE + CA
Sbjct: 447 CDCIPGWKGINCHINVNDC--RGQCQHGGTCKDLV-NGYQCVCPRGFGGRHCELERDKCA 503
Query: 321 PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE 379
PC + G C GF C C +G+ G PC +GA C + + C
Sbjct: 504 SSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCA 561
Query: 380 CADGWTGPACAEDVDECSGRS--MTEG-------------ALGPCVNAAACNNTAGG-YS 423
C D + G C+ + C G + + +G A G C C + GG +S
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C +G+TG C N+DDC GQ C +G TCID VD F C C +G+ G C + +DC P
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC + G C DL+N + C C G+ G C C C NG CY + + C C PG
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
W G C V ++ C C NGGTCV S+
Sbjct: 742 WKGSTCA-------------VAKNSSCLPNPCVNGGTCVGSGASF----SCICRDGWEGR 784
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGW-ACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG C+ W C C G G C +++D C SSPC G
Sbjct: 785 TCTHNTNDCNPLPCYNGGICVDGV---NWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 841
Query: 662 CVGGSGWWMCECVAGWTGETC 682
CV + C C G G C
Sbjct: 842 CVDEINGYRCSCPPGRAGPRC 862
Score = 66.9 bits (156), Expect = 3e-10
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ +A P + C C +G +G CE + C S+PC NGG C + C C +GW+
Sbjct: 320 GGTCI-NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 679 GETCAVRV 686
G TCA+ +
Sbjct: 379 GPTCALDI 386
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 575 bits (1419), Expect = e-163
Identities = 274/700 (39%), Positives = 349/700 (49%), Gaps = 43/700 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 28 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 87
Query: 74 CSFGRAASPVLGTDSFTLA------------------EPLYTLALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L + + +PF F W RSFTLI++
Sbjct: 88 CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVE 147
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 148 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 207
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 267
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 268 WQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCALD 385
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
AS PC G +C D +DGF C C + W G C D +EC G+ PC+NA +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK--------PCLNAFS 437
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C N GGY C C+ GW G +C NV+DC GQC HG TC DLV+ + C C G+ GR C L
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCEL 497
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
+ D CA PC +GG C DL + + C CP GFSG CE D D C SPC NGA CY + D
Sbjct: 498 ERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 557
Query: 535 YYCHCAPGWTGKNCT-QRAARDRKTCSVL--------VEESERCAEGMCANGGTCVREEG 585
YYC C + GKNC+ R C V+ A G+C G CV + G
Sbjct: 558 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 617
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
+ + GGTC+ + C C G G LC+
Sbjct: 618 G---NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV--DAFRCFCPSGWEGELCD 672
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
+ + C PC + GRC + C C GW G+TC R
Sbjct: 673 TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 295 bits (725), Expect = 4e-79
Identities = 192/642 (29%), Positives = 257/642 (40%), Gaps = 102/642 (15%)
Query: 198 CLPGWQGDNCEKP--VCKEGCHPTHGRCDR-PG--DCDCRPGWRGELCS----QCQPYPG 248
C G+ G NCEK C G C P +C C GW G C+ +C P
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C ++C C W G C D N C +PC + +C+N Y+C C G
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDANEC-EGKPCLNAFSCKNLIGG-YYCDCIPG 452
Query: 307 FSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
+ G++C N C Q C HG TC G+ C C RG+GG AS PC
Sbjct: 453 WKGINCHINVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCELERDKCASSPCHS 509
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C D DGF C C G++GP C DVD C PC N A C N G Y CA
Sbjct: 510 GGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNGARCYNLEGDYYCA 561
Query: 426 CLAGWTGRDCETN-----------VDDC-------------TGQC-LHGATCIDLVDDFH 460
C + G++C +D C +G C HG +F
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G C+ + + C
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + CY +D+YC C GW GK C R + C C+NGGTC
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ--------------CDAYTCSNGGTC 727
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
++R + GGTC+ S ++C CR+G
Sbjct: 728 YDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA--SFSCICRDGWE 782
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXX 700
G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID------ECQSSPC 836
Query: 701 XXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNV 760
+ RC C PP RA RC E + ++R P
Sbjct: 837 AYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------GFGRSCWSRGTP-- 878
Query: 761 GDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
+G+ W CN+C C G C+++WCG CL
Sbjct: 879 --------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 912
Score = 265 bits (649), Expect = 6e-70
Identities = 169/561 (30%), Positives = 225/561 (40%), Gaps = 69/561 (12%)
Query: 166 QPNYYNTTCTTFCRPRDDKFGHYSCT-------------PDG-DKHCLPGWQGDNCEKPV 211
+P+ Y TC R+ + ++CT P G + HC GW G C +
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 212 CKEGCHP--THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWD 260
+ +P G C D C C W G C ++C+ P C +
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYY 446
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C W GI C ++N C CQHGGTC++ + Y C C GF G CE + CA
Sbjct: 447 CDCIPGWKGINCHINVNDC--RGQCQHGGTCKDLV-NGYQCVCPRGFGGRHCELERDKCA 503
Query: 321 PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE 379
PC + G C GF C C +G+ G PC +GA C + + C
Sbjct: 504 SSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCA 561
Query: 380 CADGWTGPACAEDVDECSGRS--MTEG-------------ALGPCVNAAACNNTAGG-YS 423
C D + G C+ + C G + + +G A G C C + GG +S
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C +G+TG C N+DDC GQ C +G TCID VD F C C +G+ G C + +DC P
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC + G C DL+N + C C G+ G C C C NG CY + + C C PG
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
W G C V ++ C C NGGTCV S+
Sbjct: 742 WKGSTCA-------------VAKNSSCLPNPCVNGGTCVGSGASF----SCICRDGWEGR 784
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGW-ACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG C+ W C C G G C +++D C SSPC G
Sbjct: 785 TCTHNTNDCNPLPCYNGGICVDGV---NWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 841
Query: 662 CVGGSGWWMCECVAGWTGETC 682
CV + C C G G C
Sbjct: 842 CVDEINGYRCSCPPGRAGPRC 862
Score = 66.9 bits (156), Expect = 3e-10
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ +A P + C C +G +G CE + C S+PC NGG C + C C +GW+
Sbjct: 320 GGTCI-NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 679 GETCAVRV 686
G TCA+ +
Sbjct: 379 GPTCALDI 386
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 573 bits (1414), Expect = e-162
Identities = 274/701 (39%), Positives = 350/701 (49%), Gaps = 44/701 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 12 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 71
Query: 74 CSFGRAASPVLGTDSFTLA------------------EPLYTLALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L + + +PF F W RSFTLI++
Sbjct: 72 CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVE 131
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 132 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 191
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 192 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 251
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 252 WQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 310
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 311 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCASA 369
Query: 355 XXXX-ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAA 413
AS PC G +C D +DGF C C + W G C D +EC G+ PC+NA
Sbjct: 370 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK--------PCLNAF 421
Query: 414 ACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
+C N GGY C C+ GW G +C NV+DC GQC HG TC DLV+ + C C G+ GR C
Sbjct: 422 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 481
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
L+ D+CA PC +GG C DL + + C CP GFSG CE D D C SPC NGA CY +
Sbjct: 482 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 541
Query: 534 DYYCHCAPGWTGKNCT-QRAARDRKTCSVL--------VEESERCAEGMCANGGTCVREE 584
DYYC C + GKNC+ R C V+ A G+C G CV +
Sbjct: 542 DYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP 601
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
G + + GGTC+ + C C G G LC
Sbjct: 602 GG---NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV--DAFRCFCPSGWEGELC 656
Query: 645 ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
+ + + C PC + GRC + C C GW G+TC R
Sbjct: 657 DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 697
Score = 295 bits (723), Expect = 7e-79
Identities = 192/643 (29%), Positives = 257/643 (39%), Gaps = 103/643 (16%)
Query: 198 CLPGWQGDNCEKP--VCKEGCHPTHGRCDR-PG--DCDCRPGWRGELCS-----QCQPYP 247
C G+ G NCEK C G C P +C C GW G C+ +C P
Sbjct: 319 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASNP 378
Query: 248 GCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
G C ++C C W G C D N C +PC + +C+N Y+C C
Sbjct: 379 CAAGGTCVDQVDGFECICPEQWVGATCQLDANEC-EGKPCLNAFSCKNLIGG-YYCDCIP 436
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
G+ G++C N C Q C HG TC G+ C C RG+GG AS PC
Sbjct: 437 GWKGINCHINVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCELERDECASSPCH 493
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C D DGF C C G++GP C DVD C PC N A C N G Y C
Sbjct: 494 SGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNGARCYNLEGDYYC 545
Query: 425 ACLAGWTGRDCETN-----------VDDC-------------TGQC-LHGATCIDLVDDF 459
AC + G++C +D C +G C HG +F
Sbjct: 546 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 605
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G C+ + + C
Sbjct: 606 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 665
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC + CY +D+YC C GW GK C R + C C+NGGT
Sbjct: 666 DPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ--------------CDAYTCSNGGT 711
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
C ++R + GGTC+ S ++C CR+G
Sbjct: 712 CYDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA--SFSCICRDGW 766
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXX 699
G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 767 EGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID------ECQSSP 820
Query: 700 XXXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPN 759
+ RC C PP RA RC E + ++R P
Sbjct: 821 CAYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------GFGRSCWSRGTP- 863
Query: 760 VGDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
+G+ W CN+C C G C+++WCG CL
Sbjct: 864 ---------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 897
Score = 263 bits (644), Expect = 2e-69
Identities = 169/562 (30%), Positives = 222/562 (39%), Gaps = 70/562 (12%)
Query: 166 QPNYYNTTCTTFCRPRDDKFGHYSCT-------------PDG-DKHCLPGWQGDNCEKP- 210
+P+ Y TC R+ + ++CT P G + HC GW G C
Sbjct: 311 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASAD 370
Query: 211 --VCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSW 259
C G C D C C W G C ++C+ P C +
Sbjct: 371 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGY 430
Query: 260 DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C W GI C ++N C CQHGGTC++ + Y C C GF G CE + C
Sbjct: 431 YCDCIPGWKGINCHINVNDC--RGQCQHGGTCKDLV-NGYQCVCPRGFGGRHCELERDEC 487
Query: 320 APQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTC 378
A PC + G C GF C C +G+ G PC +GA C + + C
Sbjct: 488 ASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYC 545
Query: 379 ECADGWTGPACAEDVDECSGRS--MTEG-------------ALGPCVNAAACNNTAGG-Y 422
C D + G C+ + C G + + +G A G C C + GG +
Sbjct: 546 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 605
Query: 423 SCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
SC C +G+TG C N+DDC GQ C +G TCID VD F C C +G+ G C + +DC P
Sbjct: 606 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 665
Query: 482 RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
PC + G C DL+N + C C G+ G C C C NG CY + + C C P
Sbjct: 666 DPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 725
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
GW G C V ++ C C NGGTCV S+
Sbjct: 726 GWKGSTCA-------------VAKNSSCLPNPCVNGGTCVGSGASF----SCICRDGWEG 768
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGW-ACGCREGRTGALCELSLDLCGSSPCRNGG 660
GG C+ W C C G G C +++D C SSPC G
Sbjct: 769 RTCTHNTNDCNPLPCYNGGICVDGV---NWFRCECAPGFAGPDCRINIDECQSSPCAYGA 825
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
CV + C C G G C
Sbjct: 826 TCVDEINGYRCSCPPGRAGPRC 847
Score = 204 bits (498), Expect = 1e-51
Identities = 118/362 (32%), Positives = 150/362 (41%), Gaps = 28/362 (7%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKH 251
HC G+ G CE V C+ RC + GD C C + G+ CS P C
Sbjct: 508 HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV--PREPCPG 565
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C C D G+ CG H G C + + C C GF+G
Sbjct: 566 GACRVID-GCGSDAG-PGMPGTAASGVCGPH------GRCVSQPGGNFSCICDSGFTGTY 617
Query: 312 CERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR 370
C + C QPC +G TC F C C GW G PC C
Sbjct: 618 CHENIDDCLGQPCRNGGTC--IDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 675
Query: 371 DHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
D ++ F C C DGW G C +C + C N C ++ + CAC GW
Sbjct: 676 DLVNDFYCACDDGWKGKTCHSREFQCDAYT--------CSNGGTCYDSGDTFRCACPPGW 727
Query: 431 TGRDCET--NVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
G C N C++G TC+ F C C G+ GRTC+ + +DC P PC NGG
Sbjct: 728 KGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGG 787
Query: 489 ECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
CVD +N +RC C GF+G +C + D C SPC GA C + Y C C PG G C
Sbjct: 788 ICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 847
Query: 549 TQ 550
+
Sbjct: 848 QE 849
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 506 bits (1249), Expect = e-142
Identities = 254/701 (36%), Positives = 325/701 (46%), Gaps = 47/701 (6%)
Query: 14 GVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAAPGGS 73
G FELQ+ N E+ C T +CLKEYQ+ P G
Sbjct: 28 GYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP 87
Query: 74 CSFGRAASPVLGTDSFTLA------------------EPLYTLALPFSFRWTRSFTLILQ 115
CS+G A+PVLG +SF L + + +PF F W RSFTLI++
Sbjct: 88 CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVE 147
Query: 116 AYD-DYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTC 174
A+D D + + E LIE +G++ P W C NYY+ TC
Sbjct: 148 AWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATC 207
Query: 175 TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG 234
FCRPR+D FGHY+C G+K C+ GW G C++ VCK+GC+ HG C PG+C C G
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYG 267
Query: 235 WRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT 294
W+G C +C PYPGC HG C W C C+TNWGG+LCD+DLNYCG+H PC +GGTC N
Sbjct: 268 WQGRFCDECVPYPGCVHGSC-VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
PDQY C C +G+SG +CE+ ++ C PCA+G S GF C C GW G
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG-SCHEVPSGFECHCPSGWSGPTCALD 385
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
AS PC G +C D +DGF C C + W G C DV++C G+ C +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ---------CQHGGT 436
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C + GY C C G+ GR CE D C + C G C DL D FHC C G++G C
Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC----GNGAACY 529
+DVD C P PC NG C +L Y C CP F G NC R+ C G C G G+
Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 556
Query: 530 TAQSDYYCHCAPGWTGKNCTQRAARDRKTC------SVLVEESERCAEGMCANGGTCVRE 583
G G+ +Q C + E + C C NGGTC+ E
Sbjct: 557 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 616
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
++R D+ + G C L + C C +G G
Sbjct: 617 VDAFRCFCPSGWEGELCDT----NPNDCLPDPCHSRGRCYD--LVNDFYCACDDGWKGKT 670
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C C + C NGG C + C C GW G TCAV
Sbjct: 671 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAV 711
Score = 292 bits (716), Expect = 5e-78
Identities = 195/655 (29%), Positives = 263/655 (40%), Gaps = 104/655 (15%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCH---PTHGRC--DRPGD--CDCRPGWRGEL 239
H SC +C W G C+K + G H G C P C C G+ G
Sbjct: 284 HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRN 343
Query: 240 CSQ----CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCEN 293
C + C P G C+ S ++C C + W G C D++ C ++ PC GGTC +
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASN-PCAAGGTCVD 402
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXX 352
D + C C E + G C+ N C Q C HG TC G+ C C RG+GG
Sbjct: 403 QV-DGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCK--DLVNGYQCVCPRGFGGRHCE 458
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
AS PC G C D DGF C C G++GP C DVD C PC N
Sbjct: 459 LERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP--------SPCRNG 510
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN-----------VDDC-------------TGQC-L 447
A C N G Y CAC + G++C +D C +G C
Sbjct: 511 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 570
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
HG +F C C +G+ G C ++DDC +PC NGG C+D ++A+RC CP G+ G
Sbjct: 571 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 630
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
C+ + + C PC + CY +D+YC C GW GK C R +
Sbjct: 631 ELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ------------- 677
Query: 568 RCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSAL 627
C C+NGGTC ++R + GGTC+ S
Sbjct: 678 -CDAYTCSNGGTCYDSGDTFRCACPPGWKGS---TCAVAKNSSCLPNPCVNGGTCVGSGA 733
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
++C CR+G G C + + C PC NGG CV G W+ CEC G+ G C + +
Sbjct: 734 --SFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID 791
Query: 688 XXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQN 747
+ RC C PP RA RC E +
Sbjct: 792 ------ECQSSPCAYGATCVDEINGYRCSC--PPGRAGPRCQEVI--------------G 829
Query: 748 DNHGVYNRPDPNVGDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGLPDCL 801
++R P +G+ W CN+C C G C+++WCG CL
Sbjct: 830 FGRSCWSRGTP----------FPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCL 874
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 423 bits (1042), Expect = e-117
Identities = 190/473 (40%), Positives = 250/473 (52%), Gaps = 25/473 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTL-----AEPLYT--LALPFSFR 105
CRT F +CLK YQ++ +P C++G A +PVLG DSF+L A+ ++ + PF F
Sbjct: 56 CRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGGADSAFSNPIRFPFGFT 115
Query: 106 WTRSFTLILQAY-----DDYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXX 160
W +F+LI++A DD PE LI + EW
Sbjct: 116 WPGTFSLIIEALHTDSPDDLATENPER-LISRLATQRHLTVGEEWSQDLHSSGRTDLKYS 174
Query: 161 XXXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH 220
+C +YY C+ FCRPRDD FGH++C G+K C PGW+G C +P+C GC H
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G CD+PG+C CR GW+G C +C YPGC HG C W C C WGG+ C+QDLNYC
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQ-QPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
H+PC++G TC NT Y C C G++G CE + C P PC +G S ++C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDLENSYSC 352
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGR 399
TC G+ G A GPC +G C D D G++C C G++G C + +D CS
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS- 411
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD 458
PC N A C + Y C C AG++GR C+ NVDDC + C +G TC D V+D
Sbjct: 412 -------SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
F C C GY GR CS V C PC NG C + + Y C C G+ G NC+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNCQ 517
Score = 259 bits (635), Expect = 3e-68
Identities = 127/335 (37%), Positives = 174/335 (51%), Gaps = 25/335 (7%)
Query: 220 HGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCNGSSWDCTCDTNWGGILCDQDLN 277
H C G+ C PGW+G C++ PGC +HG+C+ +C C W G CD+ +
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG-ECKCRVGWQGRYCDECIR 259
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP-QPCAHG-TCSLAGTT 335
Y G C HG TC+ P Q C C EG+ G+ C + N C +PC +G TC+ G
Sbjct: 260 YPG----CLHG-TCQQ--PWQ--CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
+TC+C G+ G PC +G SC D + ++C C G+ G C
Sbjct: 311 -SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 396 CSGRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCI 453
C+ GPC N C+++ GGYSC C G++G +CE +D C+ C +GA C+
Sbjct: 370 CAD--------GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DL D + C C AG++GR C +VDDCA PC NGG C D +N + C CP G++G NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C +PC NGA C+ Y C CA G+ G NC
Sbjct: 482 VSRCEHAPCHNGATCHERGHGYVCECARGYGGPNC 516
Score = 223 bits (545), Expect = 2e-57
Identities = 123/356 (34%), Positives = 165/356 (46%), Gaps = 44/356 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + GE CS C+P + G + C+ W G C + + G E QHG
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE--QHG- 235
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C+ P + C+C G+ G C+ C P C HGTC + + C C GWGG
Sbjct: 236 FCDK--PGE--CKCRVGWQGRYCDE----CIRYPGCLHGTCQ-----QPWQCNCQEGWGG 282
Query: 349 XXXXXXXXXXASG-PCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + G +TC C G+TG C +DEC
Sbjct: 283 LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP-------- 334
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD-FHCACA 464
PC N +C + YSC C G+ G+ CE + C G C +G C D D + C C
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGN 524
GY+G C +D C+ PC+NG +CVDL +AY C C GFSG +C+D+ D CA SPC N
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
G C +D+ C C PG+TG+NC+ + RC C NG TC
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVS--------------RCEHAPCHNGATC 496
Score = 165 bits (400), Expect = 9e-40
Identities = 98/325 (30%), Positives = 129/325 (39%), Gaps = 42/325 (12%)
Query: 380 CADGWTGPACAEDV---------------DECSGRSMTEGAL-GPCVNAAAC--NNTAGG 421
C GW GP C E + EC R +G C+ C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP 271
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ--CLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDD 478
+ C C GW G C +++ CT C +GATC + + C+C GY G TC L +D+
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
C P PC NGG C DL N+Y C CP GF G CE CA PC NG C + Y C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G++G NC ++ + C+ C+NG CV ++
Sbjct: 392 RCPVGYSGFNCEKKI--------------DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
D GGTC ++C C G TG C + C +PC
Sbjct: 438 RHCDDNVDDCASSPCAN----GGTCRDGV--NDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG C ++CEC G+ G C
Sbjct: 492 NGATCHERGHGYVCECARGYGGPNC 516
Score = 72.9 bits (171), Expect = 5e-12
Identities = 62/226 (27%), Positives = 83/226 (36%), Gaps = 33/226 (14%)
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C G+ G C+ + C P G C C C VG+ G C D C P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYP- 261
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
G T Q + C+C GW G C Q D C+ C NG TC
Sbjct: 262 --GCLHGTCQQPWQCNCQEGWGGLFCNQ----DLNYCT---------HHKPCKNGATCTN 306
Query: 583 E-EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
+GS+ + + GG+C + L ++C C G G
Sbjct: 307 TGQGSYTCSCRPGYTGATCE----LGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYG 360
Query: 642 ALCELSLDLCGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRV 686
+CELS C PC NGGRC G + C C G++G C ++
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI 406
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 423 bits (1042), Expect = e-117
Identities = 190/473 (40%), Positives = 250/473 (52%), Gaps = 25/473 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTL-----AEPLYT--LALPFSFR 105
CRT F +CLK YQ++ +P C++G A +PVLG DSF+L A+ ++ + PF F
Sbjct: 56 CRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGGADSAFSNPIRFPFGFT 115
Query: 106 WTRSFTLILQAY-----DDYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXX 160
W +F+LI++A DD PE LI + EW
Sbjct: 116 WPGTFSLIIEALHTDSPDDLATENPER-LISRLATQRHLTVGEEWSQDLHSSGRTDLKYS 174
Query: 161 XXXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH 220
+C +YY C+ FCRPRDD FGH++C G+K C PGW+G C +P+C GC H
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G CD+PG+C CR GW+G C +C YPGC HG C W C C WGG+ C+QDLNYC
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQ-QPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
H+PC++G TC NT Y C C G++G CE + C P PC +G S ++C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDLENSYSC 352
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGR 399
TC G+ G A GPC +G C D D G++C C G++G C + +D CS
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS- 411
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD 458
PC N A C + Y C C AG++GR C+ NVDDC + C +G TC D V+D
Sbjct: 412 -------SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
F C C GY GR CS V C PC NG C + + Y C C G+ G NC+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNCQ 517
Score = 259 bits (635), Expect = 3e-68
Identities = 127/335 (37%), Positives = 174/335 (51%), Gaps = 25/335 (7%)
Query: 220 HGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCNGSSWDCTCDTNWGGILCDQDLN 277
H C G+ C PGW+G C++ PGC +HG+C+ +C C W G CD+ +
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG-ECKCRVGWQGRYCDECIR 259
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP-QPCAHG-TCSLAGTT 335
Y G C HG TC+ P Q C C EG+ G+ C + N C +PC +G TC+ G
Sbjct: 260 YPG----CLHG-TCQQ--PWQ--CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
+TC+C G+ G PC +G SC D + ++C C G+ G C
Sbjct: 311 -SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 396 CSGRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCI 453
C+ GPC N C+++ GGYSC C G++G +CE +D C+ C +GA C+
Sbjct: 370 CAD--------GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DL D + C C AG++GR C +VDDCA PC NGG C D +N + C CP G++G NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C +PC NGA C+ Y C CA G+ G NC
Sbjct: 482 VSRCEHAPCHNGATCHERGHGYVCECARGYGGPNC 516
Score = 223 bits (545), Expect = 2e-57
Identities = 123/356 (34%), Positives = 165/356 (46%), Gaps = 44/356 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + GE CS C+P + G + C+ W G C + + G E QHG
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE--QHG- 235
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C+ P + C+C G+ G C+ C P C HGTC + + C C GWGG
Sbjct: 236 FCDK--PGE--CKCRVGWQGRYCDE----CIRYPGCLHGTCQ-----QPWQCNCQEGWGG 282
Query: 349 XXXXXXXXXXASG-PCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + G +TC C G+TG C +DEC
Sbjct: 283 LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP-------- 334
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD-FHCACA 464
PC N +C + YSC C G+ G+ CE + C G C +G C D D + C C
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGN 524
GY+G C +D C+ PC+NG +CVDL +AY C C GFSG +C+D+ D CA SPC N
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
G C +D+ C C PG+TG+NC+ + RC C NG TC
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVS--------------RCEHAPCHNGATC 496
Score = 165 bits (400), Expect = 9e-40
Identities = 98/325 (30%), Positives = 129/325 (39%), Gaps = 42/325 (12%)
Query: 380 CADGWTGPACAEDV---------------DECSGRSMTEGAL-GPCVNAAAC--NNTAGG 421
C GW GP C E + EC R +G C+ C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP 271
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ--CLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDD 478
+ C C GW G C +++ CT C +GATC + + C+C GY G TC L +D+
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
C P PC NGG C DL N+Y C CP GF G CE CA PC NG C + Y C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G++G NC ++ + C+ C+NG CV ++
Sbjct: 392 RCPVGYSGFNCEKKI--------------DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
D GGTC ++C C G TG C + C +PC
Sbjct: 438 RHCDDNVDDCASSPCAN----GGTCRDGV--NDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG C ++CEC G+ G C
Sbjct: 492 NGATCHERGHGYVCECARGYGGPNC 516
Score = 72.9 bits (171), Expect = 5e-12
Identities = 62/226 (27%), Positives = 83/226 (36%), Gaps = 33/226 (14%)
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C G+ G C+ + C P G C C C VG+ G C D C P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYP- 261
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
G T Q + C+C GW G C Q D C+ C NG TC
Sbjct: 262 --GCLHGTCQQPWQCNCQEGWGGLFCNQ----DLNYCT---------HHKPCKNGATCTN 306
Query: 583 E-EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
+GS+ + + GG+C + L ++C C G G
Sbjct: 307 TGQGSYTCSCRPGYTGATCE----LGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYG 360
Query: 642 ALCELSLDLCGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRV 686
+CELS C PC NGGRC G + C C G++G C ++
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI 406
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 423 bits (1041), Expect = e-117
Identities = 190/473 (40%), Positives = 250/473 (52%), Gaps = 25/473 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTL-----AEPLYT--LALPFSFR 105
CRT F +CLK YQ++ +P C++G A +PVLG DSF+L A+ ++ + PF F
Sbjct: 56 CRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGGADSAFSNPIRFPFGFT 115
Query: 106 WTRSFTLILQAY-----DDYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXX 160
W +F+LI++A DD PE LI + EW
Sbjct: 116 WPGTFSLIIEALHTDSPDDLATENPER-LISRLATQRHLTVGEEWSQDLHSSGRTDLKYS 174
Query: 161 XXXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH 220
+C +YY C+ FCRPRDD FGH++C G+K C PGW+G C +P+C GC H
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G CD+PG+C CR GW+G C +C YPGC HG C W C C WGG+ C+QDLNYC
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQ-QPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
H+PC++G TC NT Y C C G++G CE + C P PC +G S ++C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDLENSYSC 352
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGR 399
TC G+ G A GPC +G C D D G++C C G++G C + +D CS
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS- 411
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD 458
PC N A C + Y C C AG++GR C+ NVDDC + C +G TC D V+D
Sbjct: 412 -------SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
F C C GY GR CS V C PC NG C + + Y C C G+ G NC+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 259 bits (634), Expect = 4e-68
Identities = 127/335 (37%), Positives = 174/335 (51%), Gaps = 25/335 (7%)
Query: 220 HGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCNGSSWDCTCDTNWGGILCDQDLN 277
H C G+ C PGW+G C++ PGC +HG+C+ +C C W G CD+ +
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG-ECKCRVGWQGRYCDECIR 259
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP-QPCAHG-TCSLAGTT 335
Y G C HG TC+ P Q C C EG+ G+ C + N C +PC +G TC+ G
Sbjct: 260 YPG----CLHG-TCQQ--PWQ--CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
+TC+C G+ G PC +G SC D + ++C C G+ G C
Sbjct: 311 -SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 396 CSGRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCI 453
C+ GPC N C+++ GGYSC C G++G +CE +D C+ C +GA C+
Sbjct: 370 CAD--------GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DL D + C C AG++GR C +VDDCA PC NGG C D +N + C CP G++G NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C +PC NGA C+ Y C CA G+ G NC
Sbjct: 482 VSRCEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 223 bits (545), Expect = 2e-57
Identities = 123/356 (34%), Positives = 165/356 (46%), Gaps = 44/356 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + GE CS C+P + G + C+ W G C + + G E QHG
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE--QHG- 235
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C+ P + C+C G+ G C+ C P C HGTC + + C C GWGG
Sbjct: 236 FCDK--PGE--CKCRVGWQGRYCDE----CIRYPGCLHGTCQ-----QPWQCNCQEGWGG 282
Query: 349 XXXXXXXXXXASG-PCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + G +TC C G+TG C +DEC
Sbjct: 283 LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP-------- 334
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD-FHCACA 464
PC N +C + YSC C G+ G+ CE + C G C +G C D D + C C
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGN 524
GY+G C +D C+ PC+NG +CVDL +AY C C GFSG +C+D+ D CA SPC N
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
G C +D+ C C PG+TG+NC+ + RC C NG TC
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVS--------------RCEHAPCHNGATC 496
Score = 164 bits (399), Expect = 1e-39
Identities = 98/325 (30%), Positives = 129/325 (39%), Gaps = 42/325 (12%)
Query: 380 CADGWTGPACAEDV---------------DECSGRSMTEGAL-GPCVNAAAC--NNTAGG 421
C GW GP C E + EC R +G C+ C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP 271
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ--CLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDD 478
+ C C GW G C +++ CT C +GATC + + C+C GY G TC L +D+
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
C P PC NGG C DL N+Y C CP GF G CE CA PC NG C + Y C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G++G NC ++ + C+ C+NG CV ++
Sbjct: 392 RCPVGYSGFNCEKKI--------------DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
D GGTC ++C C G TG C + C +PC
Sbjct: 438 RHCDDNVDDCASSPCAN----GGTCRDGV--NDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG C ++CEC G+ G C
Sbjct: 492 NGATCHERGHRYVCECARGYGGPNC 516
Score = 72.9 bits (171), Expect = 5e-12
Identities = 62/226 (27%), Positives = 83/226 (36%), Gaps = 33/226 (14%)
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C G+ G C+ + C P G C C C VG+ G C D C P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYP- 261
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
G T Q + C+C GW G C Q D C+ C NG TC
Sbjct: 262 --GCLHGTCQQPWQCNCQEGWGGLFCNQ----DLNYCT---------HHKPCKNGATCTN 306
Query: 583 E-EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
+GS+ + + GG+C + L ++C C G G
Sbjct: 307 TGQGSYTCSCRPGYTGATCE----LGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYG 360
Query: 642 ALCELSLDLCGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRV 686
+CELS C PC NGGRC G + C C G++G C ++
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI 406
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 423 bits (1041), Expect = e-117
Identities = 190/473 (40%), Positives = 250/473 (52%), Gaps = 25/473 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTL-----AEPLYT--LALPFSFR 105
CRT F +CLK YQ++ +P C++G A +PVLG DSF+L A+ ++ + PF F
Sbjct: 56 CRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGGADSAFSNPIRFPFGFT 115
Query: 106 WTRSFTLILQAY-----DDYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXX 160
W +F+LI++A DD PE LI + EW
Sbjct: 116 WPGTFSLIIEALHTDSPDDLATENPER-LISRLATQRHLTVGEEWSQDLHSSGRTDLKYS 174
Query: 161 XXXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH 220
+C +YY C+ FCRPRDD FGH++C G+K C PGW+G C +P+C GC H
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G CD+PG+C CR GW+G C +C YPGC HG C W C C WGG+ C+QDLNYC
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQ-QPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
H+PC++G TC NT Y C C G++G CE + C P PC +G S ++C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDLENSYSC 352
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGR 399
TC G+ G A GPC +G C D D G++C C G++G C + +D CS
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS- 411
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD 458
PC N A C + Y C C AG++GR C+ NVDDC + C +G TC D V+D
Sbjct: 412 -------SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
F C C GY GR CS V C PC NG C + + Y C C G+ G NC+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 259 bits (634), Expect = 4e-68
Identities = 127/335 (37%), Positives = 174/335 (51%), Gaps = 25/335 (7%)
Query: 220 HGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCNGSSWDCTCDTNWGGILCDQDLN 277
H C G+ C PGW+G C++ PGC +HG+C+ +C C W G CD+ +
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG-ECKCRVGWQGRYCDECIR 259
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP-QPCAHG-TCSLAGTT 335
Y G C HG TC+ P Q C C EG+ G+ C + N C +PC +G TC+ G
Sbjct: 260 YPG----CLHG-TCQQ--PWQ--CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
+TC+C G+ G PC +G SC D + ++C C G+ G C
Sbjct: 311 -SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 396 CSGRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCI 453
C+ GPC N C+++ GGYSC C G++G +CE +D C+ C +GA C+
Sbjct: 370 CAD--------GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DL D + C C AG++GR C +VDDCA PC NGG C D +N + C CP G++G NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C +PC NGA C+ Y C CA G+ G NC
Sbjct: 482 VSRCEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 223 bits (545), Expect = 2e-57
Identities = 123/356 (34%), Positives = 165/356 (46%), Gaps = 44/356 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + GE CS C+P + G + C+ W G C + + G E QHG
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE--QHG- 235
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C+ P + C+C G+ G C+ C P C HGTC + + C C GWGG
Sbjct: 236 FCDK--PGE--CKCRVGWQGRYCDE----CIRYPGCLHGTCQ-----QPWQCNCQEGWGG 282
Query: 349 XXXXXXXXXXASG-PCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + G +TC C G+TG C +DEC
Sbjct: 283 LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP-------- 334
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD-FHCACA 464
PC N +C + YSC C G+ G+ CE + C G C +G C D D + C C
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGN 524
GY+G C +D C+ PC+NG +CVDL +AY C C GFSG +C+D+ D CA SPC N
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
G C +D+ C C PG+TG+NC+ + RC C NG TC
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVS--------------RCEHAPCHNGATC 496
Score = 164 bits (399), Expect = 1e-39
Identities = 98/325 (30%), Positives = 129/325 (39%), Gaps = 42/325 (12%)
Query: 380 CADGWTGPACAEDV---------------DECSGRSMTEGAL-GPCVNAAAC--NNTAGG 421
C GW GP C E + EC R +G C+ C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP 271
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ--CLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDD 478
+ C C GW G C +++ CT C +GATC + + C+C GY G TC L +D+
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
C P PC NGG C DL N+Y C CP GF G CE CA PC NG C + Y C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G++G NC ++ + C+ C+NG CV ++
Sbjct: 392 RCPVGYSGFNCEKKI--------------DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
D GGTC ++C C G TG C + C +PC
Sbjct: 438 RHCDDNVDDCASSPCAN----GGTCRDGV--NDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG C ++CEC G+ G C
Sbjct: 492 NGATCHERGHRYVCECARGYGGPNC 516
Score = 72.9 bits (171), Expect = 5e-12
Identities = 62/226 (27%), Positives = 83/226 (36%), Gaps = 33/226 (14%)
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C G+ G C+ + C P G C C C VG+ G C D C P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYP- 261
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
G T Q + C+C GW G C Q D C+ C NG TC
Sbjct: 262 --GCLHGTCQQPWQCNCQEGWGGLFCNQ----DLNYCT---------HHKPCKNGATCTN 306
Query: 583 E-EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
+GS+ + + GG+C + L ++C C G G
Sbjct: 307 TGQGSYTCSCRPGYTGATCE----LGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYG 360
Query: 642 ALCELSLDLCGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRV 686
+CELS C PC NGGRC G + C C G++G C ++
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI 406
>BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophila)
protein.
Length = 685
Score = 420 bits (1034), Expect = e-116
Identities = 201/519 (38%), Positives = 267/519 (51%), Gaps = 41/519 (7%)
Query: 10 AAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAA 69
AAG+GVF+LQ+ EF N R CRT F +CLK +Q+ +
Sbjct: 24 AAGSGVFQLQLQEFINER-------------GVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Query: 70 PGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWTRSFTLILQAY----DDY 120
PG C+FG ++PVLGT+SF + + L LPF+F W +F+LI++A+ DD
Sbjct: 71 PG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDL 129
Query: 121 EYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCR 179
P LI + G + W +C NYY C+ C+
Sbjct: 130 RPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCK 189
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGEL 239
R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G C +P +C CRPGW+G L
Sbjct: 190 KRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 240 CSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H PC++G TC N+ Y
Sbjct: 250 CNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSY 308
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G++GVDCE + C PC +G S G+ C C G+ G A
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 360 SGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
PC +G SCR+ G + CEC +TG C + VD C+ PC N C N
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS--------NPCANGGQCLN 419
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
C C G+TG CE +V DC C HG TC DL + C C AG++GR C +
Sbjct: 420 RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Query: 475 DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
+D CA PC N C DL + + C CP GF G+ CE
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 234
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 235 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 284
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 395
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 547 NC 548
C
Sbjct: 516 RC 517
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 231
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 232 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 278
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 279 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 331
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 332 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 495
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 252
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 418
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 472
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 257
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 258 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 314
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 315 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 361 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 416
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVS 442
>AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein.
Length = 685
Score = 420 bits (1034), Expect = e-116
Identities = 201/519 (38%), Positives = 267/519 (51%), Gaps = 41/519 (7%)
Query: 10 AAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAA 69
AAG+GVF+LQ+ EF N R CRT F +CLK +Q+ +
Sbjct: 24 AAGSGVFQLQLQEFINER-------------GVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Query: 70 PGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWTRSFTLILQAY----DDY 120
PG C+FG ++PVLGT+SF + + L LPF+F W +F+LI++A+ DD
Sbjct: 71 PG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDL 129
Query: 121 EYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCR 179
P LI + G + W +C NYY C+ C+
Sbjct: 130 RPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCK 189
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGEL 239
R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G C +P +C CRPGW+G L
Sbjct: 190 KRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 240 CSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H PC++G TC N+ Y
Sbjct: 250 CNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSY 308
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G++GVDCE + C PC +G S G+ C C G+ G A
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 360 SGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
PC +G SCR+ G + CEC +TG C + VD C+ PC N C N
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS--------NPCANGGQCLN 419
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
C C G+TG CE +V DC C HG TC DL + C C AG++GR C +
Sbjct: 420 RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Query: 475 DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
+D CA PC N C DL + + C CP GF G+ CE
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 234
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 235 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 284
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 395
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 547 NC 548
C
Sbjct: 516 RC 517
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 231
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 232 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 278
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 279 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 331
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 332 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 495
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 252
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 418
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 472
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 257
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 258 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 314
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 315 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 361 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 416
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVS 442
>AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein.
Length = 685
Score = 420 bits (1034), Expect = e-116
Identities = 201/519 (38%), Positives = 267/519 (51%), Gaps = 41/519 (7%)
Query: 10 AAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAA 69
AAG+GVF+LQ+ EF N R CRT F +CLK +Q+ +
Sbjct: 24 AAGSGVFQLQLQEFINER-------------GVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Query: 70 PGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWTRSFTLILQAY----DDY 120
PG C+FG ++PVLGT+SF + + L LPF+F W +F+LI++A+ DD
Sbjct: 71 PG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDL 129
Query: 121 EYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCR 179
P LI + G + W +C NYY C+ C+
Sbjct: 130 RPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCK 189
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGEL 239
R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G C +P +C CRPGW+G L
Sbjct: 190 KRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 240 CSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H PC++G TC N+ Y
Sbjct: 250 CNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSY 308
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G++GVDCE + C PC +G S G+ C C G+ G A
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 360 SGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
PC +G SCR+ G + CEC +TG C + VD C+ PC N C N
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS--------NPCANGGQCLN 419
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
C C G+TG CE +V DC C HG TC DL + C C AG++GR C +
Sbjct: 420 RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Query: 475 DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
+D CA PC N C DL + + C CP GF G+ CE
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 234
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 235 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 284
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 395
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 547 NC 548
C
Sbjct: 516 RC 517
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 231
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 232 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 278
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 279 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 331
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 332 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 495
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 252
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 418
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 472
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 257
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 258 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 314
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 315 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 361 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 416
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVS 442
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 420 bits (1034), Expect = e-116
Identities = 189/473 (39%), Positives = 248/473 (52%), Gaps = 25/473 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTL-----AEPLYT--LALPFSFR 105
CRT F +CLK YQ++ +P C++G A +PVLG DSF+L A+ ++ + PF F
Sbjct: 56 CRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGGADSAFSNPIRFPFGFT 115
Query: 106 WTRSFTLILQAY-----DDYEYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXX 160
W +F+LI++A DD PE LI + EW
Sbjct: 116 WPGTFSLIIEALHTDSPDDLATENPER-LISRLATQRHLTVGEEWSQDLHSSGRTDLKYS 174
Query: 161 XXXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH 220
+C +YY C+ FCRPRDD FGH++C G+K C PGW+G C +P+C GC H
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G CD+PG+C CR GW+G C +C YPGC HG C W C C WGG+ C+QDLNYC
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQ-QPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
H+PC++G TC NT Y C C G++G CE + C P PC +G S ++C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDLENSYSC 352
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGR 399
TC G+ G A GPC +G C D D G++C C G++G C + +D CS
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS- 411
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD 458
PC N A C + Y C C AG++GR C+ NVDDC + C +G TC D V+D
Sbjct: 412 -------SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
F C C GY GR CS V C PC NG C + Y C C + G NC+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYVCECARSYGGPNCQ 517
Score = 257 bits (629), Expect = 2e-67
Identities = 126/335 (37%), Positives = 173/335 (51%), Gaps = 25/335 (7%)
Query: 220 HGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCNGSSWDCTCDTNWGGILCDQDLN 277
H C G+ C PGW+G C++ PGC +HG+C+ +C C W G CD+ +
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG-ECKCRVGWQGRYCDECIR 259
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP-QPCAHG-TCSLAGTT 335
Y G C HG TC+ P Q C C EG+ G+ C + N C +PC +G TC+ G
Sbjct: 260 YPG----CLHG-TCQQ--PWQ--CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
+TC+C G+ G PC +G SC D + ++C C G+ G C
Sbjct: 311 -SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 396 CSGRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCI 453
C+ GPC N C+++ GGYSC C G++G +CE +D C+ C +GA C+
Sbjct: 370 CAD--------GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DL D + C C AG++GR C +VDDCA PC NGG C D +N + C CP G++G NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C +PC NGA C+ Y C CA + G NC
Sbjct: 482 VSRCEHAPCHNGATCHQRGHGYVCECARSYGGPNC 516
Score = 223 bits (545), Expect = 2e-57
Identities = 123/356 (34%), Positives = 165/356 (46%), Gaps = 44/356 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + GE CS C+P + G + C+ W G C + + G E QHG
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE--QHG- 235
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C+ P + C+C G+ G C+ C P C HGTC + + C C GWGG
Sbjct: 236 FCDK--PGE--CKCRVGWQGRYCDE----CIRYPGCLHGTCQ-----QPWQCNCQEGWGG 282
Query: 349 XXXXXXXXXXASG-PCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + G +TC C G+TG C +DEC
Sbjct: 283 LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP-------- 334
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD-FHCACA 464
PC N +C + YSC C G+ G+ CE + C G C +G C D D + C C
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGN 524
GY+G C +D C+ PC+NG +CVDL +AY C C GFSG +C+D+ D CA SPC N
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
G C +D+ C C PG+TG+NC+ + RC C NG TC
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVS--------------RCEHAPCHNGATC 496
Score = 162 bits (394), Expect = 5e-39
Identities = 97/325 (29%), Positives = 128/325 (39%), Gaps = 42/325 (12%)
Query: 380 CADGWTGPACAEDV---------------DECSGRSMTEGAL-GPCVNAAAC--NNTAGG 421
C GW GP C E + EC R +G C+ C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP 271
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ--CLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDD 478
+ C C GW G C +++ CT C +GATC + + C+C GY G TC L +D+
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
C P PC NGG C DL N+Y C CP GF G CE CA PC NG C + Y C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G++G NC ++ + C+ C+NG CV ++
Sbjct: 392 RCPVGYSGFNCEKKI--------------DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
D GGTC ++C C G TG C + C +PC
Sbjct: 438 RHCDDNVDDCASSPCAN----GGTCRDGV--NDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG C ++CEC + G C
Sbjct: 492 NGATCHQRGHGYVCECARSYGGPNC 516
Score = 72.9 bits (171), Expect = 5e-12
Identities = 62/226 (27%), Positives = 83/226 (36%), Gaps = 33/226 (14%)
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C G+ G C+ + C P G C C C VG+ G C D C P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYP- 261
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
G T Q + C+C GW G C Q D C+ C NG TC
Sbjct: 262 --GCLHGTCQQPWQCNCQEGWGGLFCNQ----DLNYCT---------HHKPCKNGATCTN 306
Query: 583 E-EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
+GS+ + + GG+C + L ++C C G G
Sbjct: 307 TGQGSYTCSCRPGYTGATCE----LGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYG 360
Query: 642 ALCELSLDLCGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRV 686
+CELS C PC NGGRC G + C C G++G C ++
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI 406
>AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein.
Length = 685
Score = 420 bits (1034), Expect = e-116
Identities = 201/519 (38%), Positives = 267/519 (51%), Gaps = 41/519 (7%)
Query: 10 AAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAA 69
AAG+GVF+LQ+ EF N R CRT F +CLK +Q+ +
Sbjct: 24 AAGSGVFQLQLQEFINER-------------GVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Query: 70 PGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWTRSFTLILQAY----DDY 120
PG C+FG ++PVLGT+SF + + L LPF+F W +F+LI++A+ DD
Sbjct: 71 PG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDL 129
Query: 121 EYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCR 179
P LI + G + W +C NYY C+ C+
Sbjct: 130 RPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCK 189
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGEL 239
R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G C +P +C CRPGW+G L
Sbjct: 190 KRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 240 CSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H PC++G TC N+ Y
Sbjct: 250 CNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSY 308
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G++GVDCE + C PC +G S G+ C C G+ G A
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 360 SGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
PC +G SCR+ G + CEC +TG C + VD C+ PC N C N
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS--------NPCANGGQCLN 419
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
C C G+TG CE +V DC C HG TC DL + C C AG++GR C +
Sbjct: 420 RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Query: 475 DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
+D CA PC N C DL + + C CP GF G+ CE
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 234
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 235 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 284
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 395
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 547 NC 548
C
Sbjct: 516 RC 517
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 231
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 232 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 278
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 279 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 331
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 332 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 495
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 252
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 418
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 472
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 257
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 258 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 314
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 315 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 361 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 416
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVS 442
>AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2
protein.
Length = 685
Score = 420 bits (1034), Expect = e-116
Identities = 201/519 (38%), Positives = 267/519 (51%), Gaps = 41/519 (7%)
Query: 10 AAGAGVFELQILEFSNYRLEVXXXXXXXXXXXXXXXXXXXSHPCRTRFTLCLKEYQSAAA 69
AAG+GVF+LQ+ EF N R CRT F +CLK +Q+ +
Sbjct: 24 AAGSGVFQLQLQEFINER-------------GVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Query: 70 PGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWTRSFTLILQAY----DDY 120
PG C+FG ++PVLGT+SF + + L LPF+F W +F+LI++A+ DD
Sbjct: 71 PG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDL 129
Query: 121 EYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXXXLCQPNYYNTTCTTFCR 179
P LI + G + W +C NYY C+ C+
Sbjct: 130 RPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCK 189
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGEL 239
R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G C +P +C CRPGW+G L
Sbjct: 190 KRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 240 CSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H PC++G TC N+ Y
Sbjct: 250 CNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSY 308
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G++GVDCE + C PC +G S G+ C C G+ G A
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 360 SGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
PC +G SCR+ G + CEC +TG C + VD C+ PC N C N
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS--------NPCANGGQCLN 419
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
C C G+TG CE +V DC C HG TC DL + C C AG++GR C +
Sbjct: 420 RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Query: 475 DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
+D CA PC N C DL + + C CP GF G+ CE
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 234
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 235 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 284
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 395
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 547 NC 548
C
Sbjct: 516 RC 517
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 231
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 232 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 278
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 279 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 331
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 332 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 495
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 252
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 418
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 472
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 257
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 258 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 314
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 315 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 361 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 416
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVS 442
>AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein.
Length = 653
Score = 415 bits (1022), Expect = e-115
Identities = 189/476 (39%), Positives = 252/476 (52%), Gaps = 28/476 (5%)
Query: 53 CRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTLAEPLY-----TLALPFSFRWT 107
CRT F +CLK +Q+ +PG C+FG ++PVLGT+SF + + L LPF+F W
Sbjct: 22 CRTFFRVCLKHFQAVVSPG-PCTFGTVSTPVLGTNSFAVRDDSSGGGRNPLQLPFNFTWP 80
Query: 108 RSFTLILQAY----DDYEYSE-PEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXXX 162
+F+LI++A+ DD P LI + G + W
Sbjct: 81 GTFSLIIEAWHAPGDDLRPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYR 140
Query: 163 XLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
+C NYY C+ C+ R+D FGHY C PDG+ CLPGW G+ C++P+C GCH +G
Sbjct: 141 VICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGY 200
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C +P +C CRPGW+G LC++C P+ GC+HG C+ + W CTCD WGG+ CDQDLNYC H
Sbjct: 201 CSKPAECLCRPGWQGRLCNECIPHNGCRHGTCS-TPWQCTCDEGWGGLFCDQDLNYCTHH 259
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
PC++G TC N+ Y C C G++GVDCE + C PC +G S G+ C C
Sbjct: 260 SPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDGYHCLC 318
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRS 400
G+ G A PC +G SCR+ G + CEC +TG C + VD C+
Sbjct: 319 PPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS-- 376
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDF 459
PC N C N C C G+TG CE +V DC C HG TC DL +
Sbjct: 377 ------NPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGL 430
Query: 460 HCACAAGYAGRTCSL--DVDDCAPRPCTNGGEC-VDL-LNAYRCICPVGFSGTNCE 511
C C AG++GR C + +D CA PC N C DL + + C CP GF G+ CE
Sbjct: 431 MCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 486
Score = 258 bits (633), Expect = 5e-68
Identities = 138/362 (38%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC--KHGYCN 255
C + GDNC + K H H C G+ C PGW GE C Q GC ++GYC+
Sbjct: 143 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCS 202
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ +C C W G LC N C H C+HG TC + P Q C C EG+ G+ C++
Sbjct: 203 KPA-ECLCRPGWQGRLC----NECIPHNGCRHG-TC--STPWQ--CTCDEGWGGLFCDQD 252
Query: 316 DNPCAPQ-PCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
N C PC +G TCS +G R +TCTC G+ G S PC +G SC+D
Sbjct: 253 LNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 311
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN--NTAGGYSCACLAGWT 431
DG+ C C G+ G C C+ PC N +C N Y+C C +T
Sbjct: 312 DGYHCLCPPGYYGLHCEHSTLSCAD--------SPCFNGGSCRERNQGANYACECPPNFT 363
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G +CE VD CT C +G C++ C C G+ G C L V DCA PC +GG C
Sbjct: 364 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 423
Query: 491 VDLLNAYRCICPVGFSGTNCE--DDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGK 546
DL N C CP GFSG CE D CA SPC N A CYT + + C+C G+ G
Sbjct: 424 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 483
Query: 547 NC 548
C
Sbjct: 484 RC 485
Score = 184 bits (448), Expect = 1e-45
Identities = 109/357 (30%), Positives = 150/357 (42%), Gaps = 43/357 (12%)
Query: 231 CRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C + G+ CS+ C+ Y + +C W G C Q + G HE G
Sbjct: 143 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE---QNG 199
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWGG 348
C A C C G+ G R+ N C P C HGTCS + CTCD GWGG
Sbjct: 200 YCSKPAE----CLCRPGWQG----RLCNECIPHNGCRHGTCSTP-----WQCTCDEGWGG 246
Query: 349 XXXXXXXXXXAS-GPCLHGASCRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
PC +GA+C + +TC C G+TG C ++ EC
Sbjct: 247 LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN------- 299
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD--DFHCAC 463
PC N +C + GY C C G+ G CE + C C +G +C + ++ C C
Sbjct: 300 -PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 358
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
+ G C VD C PC NGG+C++ + C C GF+GT CE CA +PC
Sbjct: 359 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 418
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
+G C+ ++ C C G++G+ C R + D CA C N TC
Sbjct: 419 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSID------------ACASSPCFNRATC 463
Score = 161 bits (391), Expect = 1e-38
Identities = 103/345 (29%), Positives = 142/345 (41%), Gaps = 53/345 (15%)
Query: 371 DHLDGFTCE------CADGWTGPACAEDV---------------DECSGRSMTEGAL-GP 408
DH + C+ C GWTG C + + EC R +G L
Sbjct: 161 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNE 220
Query: 409 CVNAAACNN--TAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVD-DFHCAC 463
C+ C + + + C C GW G C+ +++ CT C +GATC + + C C
Sbjct: 221 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 280
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C L++ +C PC NGG C D + Y C+CP G+ G +CE CA SPC
Sbjct: 281 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 340
Query: 524 NGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
NG +C ++Y C C P +TG NC ++ +RC CANGG C+
Sbjct: 341 NGGSCRERNQGANYACECPPNFTGSNCEKKV--------------DRCTSNPCANGGQCL 386
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
S + GGTC L G C C G +G
Sbjct: 387 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAH----GGTC--HDLENGLMCTCPAGFSG 440
Query: 642 ALCEL--SLDLCGSSPCRNGGRCVG--GSGWWMCECVAGWTGETC 682
CE+ S+D C SSPC N C + ++C C G+ G C
Sbjct: 441 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 485
Score = 125 bits (301), Expect = 9e-28
Identities = 81/266 (30%), Positives = 111/266 (41%), Gaps = 33/266 (12%)
Query: 425 ACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
+CL GWTG C+ + C C C + C C G+ GR C+ +C P
Sbjct: 175 SCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHN 225
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAACYTA-QSDYYCHCAP 541
G C ++C C G+ G C+ D ++C SPC NGA C + Q Y C C P
Sbjct: 226 GCRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP 282
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG +C +E SE C C NGG+C +E + +
Sbjct: 283 GYTGVDCE-------------LELSE-CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 328
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGR 661
GG+C +AC C TG+ CE +D C S+PC NGG+
Sbjct: 329 HSTLSCADSPCFN----GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQ 384
Query: 662 CVGGSGWWMCECVAGWTGETCAVRVS 687
C+ MC C G+TG C + VS
Sbjct: 385 CLNRGPSRMCRCRPGFTGTYCELHVS 410
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 311 bits (764), Expect = 7e-84
Identities = 178/549 (32%), Positives = 239/549 (43%), Gaps = 66/549 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH--GRCD---RPGDCDCRPGWRG 237
DK Y C C PG+ G C + + +P H G C+ C C G+
Sbjct: 657 DKIDGYECA------CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C HG C S + C CD W G CD + N C ++ PC +GGTC
Sbjct: 711 PTCLSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTC 768
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ Y C C EGFSG +C+ N CA PC + GTC G+ C C + G
Sbjct: 769 KDMTSG-YVCTCREGFSGPNCQTNINECASNPCLNQGTC--IDDVAGYKCNCLLPYTGAT 825
Query: 351 XXXXXXXXASGPCLHGASCRDHLD--GFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
A PC +G CR D F+C C GW G C D++EC L P
Sbjct: 826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--------VLSP 877
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGY 467
C + A+C NT GGY C C AG++GR+CET++DDC C +G +C D ++ C C G+
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGF 937
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C D+++CA PC NG C D +++Y C CP GFSG +CE++ C S C NG
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGT 997
Query: 528 CYTAQSDYYCHCAPGWTGK------------------NCTQRAARDRKTCSV------LV 563
C + + C C PG+TG C R TC
Sbjct: 998 CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Query: 564 EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXXQ 617
C C NGG C + +R D Q
Sbjct: 1058 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ 1117
Query: 618 AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
GG C+ + C C+ G TG+ CE +D C SPC+NG C G + C+CVAG+
Sbjct: 1118 HGGLCVDAG--NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Query: 678 TGETCAVRV 686
G C+ +
Sbjct: 1176 HGVNCSEEI 1184
Score = 310 bits (761), Expect = 2e-83
Identities = 167/531 (31%), Positives = 241/531 (45%), Gaps = 55/531 (10%)
Query: 178 CRPRDDKFGHYSCTPDGD-KH---CLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGD 228
C P + G +C P GD H CLPG+ G NCE+ + C G C +
Sbjct: 222 CSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
Query: 229 CDCRPGWRGELCS----QCQPYP-GCKH-GYCNGS--SWDCTCDTNWGGILCDQDLNYCG 280
C C P W G+ C+ +CQ P C++ G C+ + ++C C W G C ++++ C
Sbjct: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFT 339
+ C HG TC + ++C C G +G+ C +++ C PC G+ C
Sbjct: 341 S-AACFHGATCHDRVA-SFYCECPHGRTGLLC-HLNDACISNPCNEGSNCDTNPVNGKAI 397
Query: 340 CTCDRGWGGXXXXXXXXXXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
CTC G+ G + G PC H C + L F C+C G+TGP C DV+EC
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC- 456
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLV 456
PC N A C + G + C C+ G+ G CE N D+C + CLH C+D +
Sbjct: 457 -------VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI 509
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
++F C C G+ G C DVD+CA PC NG +C+D N Y C+C G++GT+CE D D
Sbjct: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C PC G +C + + C C PG+TG +C C+ C +
Sbjct: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNI--------------NECSSQPCRH 614
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
GGTC + ++ + GTCL G+ C C
Sbjct: 615 GGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD-----SGTCLDKI--DGYECACE 667
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G TG++C +++D C +PC NGG C G + C C G+ TC V+
Sbjct: 668 PGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 306 bits (751), Expect = 3e-82
Identities = 170/531 (32%), Positives = 234/531 (44%), Gaps = 54/531 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP-THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGC 249
C G+ C V + +P HG C + CDC PGW G C ++C+ P
Sbjct: 704 CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
Query: 250 KHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
G C S + CTC + G C ++N C ++ PC + GTC + Y C C +
Sbjct: 764 NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLNQGTCIDDVAG-YKCNCLLPY 821
Query: 308 SGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+G CE V PCAP PC +G C + F+C C GW G PC HG
Sbjct: 822 TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHG 881
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDEC------SGRSMTEG---------------- 404
ASC++ G+ C C G++G C D+D+C +G S T+G
Sbjct: 882 ASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTF 941
Query: 405 --------ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDL 455
A PC N A C + Y+C C AG++G CE N DCT C +G TC+D
Sbjct: 942 CEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDG 1001
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
++ F C C G+ G C DV++C +PC +GG C D +YRC CP G++G NC++
Sbjct: 1002 INSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH 1061
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C SPC NG C+ + Y C C GWTG C + +C V + +C
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV----SCEVAAQRQGVDVARLCQ 1117
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GG CV + G+ S Q G TC + G++C C
Sbjct: 1118 HGGLCV-DAGN---THHCRCQAGYTGSYCEDLVDECSPSPCQNGATC--TDYLGGYSCKC 1171
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
G G C +D C S PC+NGG C+ + C C G G C + V
Sbjct: 1172 VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1222
Score = 304 bits (746), Expect = 1e-81
Identities = 181/569 (31%), Positives = 243/569 (42%), Gaps = 73/569 (12%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH----CLPGWQGDNCEKPVCKEGCHPT 219
+C Y T C D HY DG C PG+ G +CE + + P
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Query: 220 H--GRC-DRPGD--CDCRPGWRGELCS----QCQPYPGCKHGYCNGS--SWDCTCDTNWG 268
G C DR C C G G C C P C G C ++C C+ +
Sbjct: 613 RHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT 671
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
G +C+ +++ C + PC +GGTCE+ + + CRC EG+ C N C PC HG
Sbjct: 672 GSMCNINIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP- 387
C + G+ C CD GW G S PC++G +C+D G+ C C +G++GP
Sbjct: 730 CR--DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
Query: 388 ------ACAED--------VDECSGRSMT----------EGALGPCV-----NAAACNNT 418
CA + +D+ +G E L PC N C +
Sbjct: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Query: 419 AG--GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
+SC C GW G+ CE ++++C C HGA+C + + C C AGY+GR C D
Sbjct: 848 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+DDC P PC NGG C D +N C C GF GT CE+D + CA PC NGA C Y
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 967
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G++G +C + C E C NGGTCV S+
Sbjct: 968 TCTCPAGFSGIHCE--------------NNTPDCTESSCFNGGTCVDGINSF----TCLC 1009
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
S GGTC + C C +G TG C+ + C SSP
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGC--GSYRCTCPQGYTGPNCQNLVHWCDSSP 1067
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NGG+C + CEC +GWTG C V
Sbjct: 1068 CKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
Score = 303 bits (745), Expect = 1e-81
Identities = 163/497 (32%), Positives = 229/497 (46%), Gaps = 44/497 (8%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
CL G+ G CE V C C D+ G+ C C PG+ G C +C P
Sbjct: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
+G C + + C C T + G LC D++ C + PC++G C + P+ Y C C EG
Sbjct: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLD-GPNTYTCVCTEG 557
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
++G CE + C P PC +G+C T FTC C G+ G +S PC HG
Sbjct: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRHG 615
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+C+D + + C C G TGP C ++D+C A PC ++ C + GY CAC
Sbjct: 616 GTCQDRDNAYLCFCLKGTTGPNCEINLDDC--------ASSPC-DSGTCLDKIDGYECAC 666
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C N+D+C G C +G TC D ++ F C C GY TC +V++C PC
Sbjct: 667 EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
+G C D LN Y+C C G+SGTNC+ + + C +PC NG C S Y C C G++G
Sbjct: 727 HGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSG 785
Query: 546 KNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXX 605
NC CA C N GTC+ + ++ +
Sbjct: 786 PNCQTNI--------------NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCE---- 827
Query: 606 XXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG 665
+ GG C S ++C C G G CE+ ++ C SPCR+G C
Sbjct: 828 VVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNT 887
Query: 666 SGWWMCECVAGWTGETC 682
G + C C AG++G C
Sbjct: 888 HGGYRCHCQAGYSGRNC 904
Score = 291 bits (713), Expect = 1e-77
Identities = 170/534 (31%), Positives = 222/534 (41%), Gaps = 61/534 (11%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGD 228
CR +D + +SC C GWQG CE + C+ G C THG
Sbjct: 844 CRQSED-YESFSCV------CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR---- 892
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C+ G+ G C C+P P G C ++ C C + G C++D+N C +
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS- 951
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+PC++G C + D Y C C GFSG+ CE C C +G + G FTC C
Sbjct: 952 DPCRNGANCTDCV-DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLC 1009
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
G+ G S PCLHG +C+D + C C G+TGP C V C
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS---- 1065
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-----------TGQCLHGAT 451
PC N C T Y C C +GWTG C+ C C HG
Sbjct: 1066 ----SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1121
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D + HC C AGY G C VD+C+P PC NG C D L Y C C G+ G NC
Sbjct: 1122 CVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Query: 512 DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
++ D C PC NG C + Y C C G G +C C+ V+ R +
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV----DDCNPPVDPVSRSPK 1237
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C N GTCV + G + + A GT +
Sbjct: 1238 --CFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNECLSNPCDARGTQNCVQRVNDF 1291
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSG---WWMCECVAGWTGETC 682
C CR G TG CE ++ C PC+NGG C S ++C+C AG+ G TC
Sbjct: 1292 HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATC 1345
Score = 289 bits (709), Expect = 3e-77
Identities = 159/505 (31%), Positives = 227/505 (44%), Gaps = 48/505 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG--DCDCRPGWRGELC----SQCQPY 246
C G+ G C + V C G +P G+C + G +C C G+ G C ++C
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 247 PGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P C + C C + G+ C+ + + C + PC H G C + +++ C C
Sbjct: 460 PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECAS-SPCLHNGRCLDKI-NEFQCECP 517
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF+G C+ + CA PC +G L G +TC C G+ G PC
Sbjct: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTCVCTEGYTGTHCEVDIDECDPDPCH 576
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC+D + FTC C G+TG C +++ECS + PC + C + Y C
Sbjct: 577 YG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQ--------PCRHGGTCQDRDNAYLC 627
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
CL G TG +CE N+DDC TC+D +D + CAC GY G C++++D+CA PC
Sbjct: 628 FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPC 687
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C D +N + C CP G+ C + + C +PC +G AC + + Y C C PGW+
Sbjct: 688 HNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKCDCDPGWS 746
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G NC + +E C C NGGTC + +
Sbjct: 747 GTNCD-------------INNNE-CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI 792
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
GTC+ G+ C C TGA CE+ L C SPCRNGG C
Sbjct: 793 NECASNPCLNQ----GTCIDDV--AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
Query: 665 GSGW--WMCECVAGWTGETCAVRVS 687
+ + C C GW G+TC V ++
Sbjct: 847 SEDYESFSCVCPTGWQGQTCEVDIN 871
Score = 277 bits (680), Expect = 1e-73
Identities = 167/513 (32%), Positives = 221/513 (43%), Gaps = 50/513 (9%)
Query: 197 HCLPGWQGDNCEKPV--CKEG-CHPTHGRCD---RPGDCDCRPGWRGELC----SQCQPY 246
HC G+ G NCE + C+ CH G C CDC PG+RG C ++C
Sbjct: 894 HCQAGYSGRNCETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 247 PGCKHGY-CNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P C++G C S+ CTC + GI C+ + C T C +GGTC + + + C C
Sbjct: 953 P-CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGI-NSFTCLC 1009
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
GF+G C+ N C QPC HG G + CTC +G+ G S PC
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCG-SYRCTCPQGYTGPNCQNLVHWCDSSPC 1068
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGG 421
+G C + CEC GWTG C C + +G C + C +
Sbjct: 1069 KNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNT 1128
Query: 422 YSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C AG+TG CE VD+C+ C +GATC D + + C C AGY G CS ++D+C
Sbjct: 1129 HHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECL 1188
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-------AGSP-CGNGAACYTAQ 532
PC NGG C+DL N Y+C CP G G +CE + D C + SP C N C
Sbjct: 1189 SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT--CVREEGSWRXX 590
Y C C PG+ G+ C + C C GT CV+ +
Sbjct: 1249 GGYSCTCPPGFVGERCEG--------------DVNECLSNPCDARGTQNCVQRVNDFHCE 1294
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-LPSALPPGWACGCREGRTGALCELSLD 649
+S + GGTC + S G+ C C G GA CE
Sbjct: 1295 CRAGHTGRRCESVINGCKGKPC----KNGGTCAVASNTARGFICKCPAGFEGATCENDAR 1350
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CGS C NGG C+ G C C+ +TG C
Sbjct: 1351 TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1383
Score = 254 bits (621), Expect = 2e-66
Identities = 151/466 (32%), Positives = 200/466 (42%), Gaps = 45/466 (9%)
Query: 236 RGELCSQCQPYPGCKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
RG CSQ P C +G C ++ C C + G C QD N C PC++ GTC
Sbjct: 20 RGPRCSQ--PGETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPC-LSTPCKNAGTCH 75
Query: 292 --ENTAPDQYFCRCAEGFSGVDC-ERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWG 347
+ Y C CA GFSG C +DN C PC +G TC L T + C C GW
Sbjct: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTE-YKCRCPPGWS 134
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG 407
G AS PC +G C + C C + GP C +DV+EC + G
Sbjct: 135 GKSCQQADPC-ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKP------G 187
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFH-CACAA 465
C + C+N G Y C C A TG +CE C+ C +G TC D H CAC
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--CG 523
G+ G+ C ++DDC C NGG CVD +N Y C CP ++G C +D D C P C
Sbjct: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NG C+ Y C C GWTG++C+ E + CA C +G TC
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCS--------------ENIDDCASAACFHGATC--- 350
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
R G C + + C C G TG
Sbjct: 351 --HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPA 408
Query: 644 CELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +D C G++PC + G+C+ G + C+C+ G+TG C + V+
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN 454
Score = 251 bits (615), Expect = 8e-66
Identities = 146/509 (28%), Positives = 214/509 (42%), Gaps = 51/509 (10%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRC---DRPGDCDCRPGWRGELCSQ----CQPYPG 248
C PGW G +C++ P C G+C + C C P + G C Q C PG
Sbjct: 129 CPPGWSGKSCQQADPCASNPC-ANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPG 187
Query: 249 -CKH-GYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H G C+ S+ C C G C++ C + PCQ+GGTC T + C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-SPSPCQNGGTCRPTGDVTHECACL 246
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
GF+G +CE + C C +G + G + C C W G P
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNA 305
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C + G+ C C +GWTG C+E++D+C A C + A C++ +
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC--------ASAACFHGATCHDRVASF 357
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATC--IDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G TG C N + C G+ C + C C +GY G CS DVD+C+
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
PC + G+C++ L ++ C C G++G CE D + C +PC N A C ++ C
Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCI 477
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
C PG+ G +C ++ CA C + G C+ + ++
Sbjct: 478 CMPGYEGVHCE--------------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH 523
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRN 658
+ G CL P + C C EG TG CE+ +D C PC
Sbjct: 524 LCQ----YDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHY 577
Query: 659 GGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G C G + C C G+TG C ++
Sbjct: 578 GS-CKDGVATFTCLCRPGYTGHHCETNIN 605
Score = 248 bits (608), Expect = 6e-65
Identities = 145/500 (29%), Positives = 216/500 (43%), Gaps = 48/500 (9%)
Query: 203 QGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCSQCQPYPG--CKH-GYCNG 256
+G C +P E C G+C+ C C + G C P CK+ G C+
Sbjct: 20 RGPRCSQP--GETCL-NGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 257 ------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
+ + C+C + G LC L+ PC++GGTC+ +Y CRC G+SG
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 311 DCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP--CLHGAS 368
C++ D PCA PCA+G L + C C + G P C HG +
Sbjct: 137 SCQQAD-PCASNPCANGGQCLPFEA-SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGT 194
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACL 427
C + + + C C TGP C CS PC N C T + CACL
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSP--------SPCQNGGTCRPTGDVTHECACL 246
Query: 428 AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPC 484
G+TG++CE N+DDC G C +G C+D V+ ++C C + G+ C+ DVD+C P C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C + Y C+C G++G +C ++ D CA + C +GA C+ + +YC C G T
Sbjct: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G +L ++ C C G C + +
Sbjct: 367 G---------------LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
+ G C+ + + C C +G TG CE+ ++ C S+PC+N C+
Sbjct: 412 DVDECSLGANPCEHAGKCINTL--GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 665 GSGWWMCECVAGWTGETCAV 684
G + C C+ G+ G C V
Sbjct: 470 QIGEFQCICMPGYEGVHCEV 489
Score = 237 bits (581), Expect = 1e-61
Identities = 165/552 (29%), Positives = 226/552 (40%), Gaps = 89/552 (16%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDK----HCLPGWQGDNCEKPV------ 211
CQ Y C T CRP G SCT DG CLPG++G CE+ +
Sbjct: 895 CQAGYSGRNCETDIDDCRPNPCHNGG-SCT-DGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 212 -CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYC-NG-------SSWDCT 262
C+ G + T C C C G+ G C P C C NG +S+ C
Sbjct: 953 PCRNGANCTD--CVDSYTCTCPAGFSGIHCENNTP--DCTESSCFNGGTCVDGINSFTCL 1008
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C D+N C + +PC HGGTC++ Y C C +G++G +C+ + + C
Sbjct: 1009 CPPGFTGSYCQHDVNECDS-QPCLHGGTCQDGC-GSYRCTCPQGYTGPNCQNLVHWCDSS 1066
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXX----------XXXXXXXXASGPCLHGASCRDH 372
PC +G T+ + C C GW G + C HG C D
Sbjct: 1067 PCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ C C G+TG C + VDECS PC N A C + GGYSC C+AG+ G
Sbjct: 1126 GNTHHCRCQAGYTGSYCEDLVDECSP--------SPCQNGATCTDYLGGYSCKCVAGYHG 1177
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR--------P 483
+C +D+C C +G TC+DL + + C+C G G C ++VDDC P
Sbjct: 1178 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK 1237
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-GNGAA-CYTAQSDYYCHCAP 541
C N G CVD + Y C CP GF G CE D + C +PC G C +D++C C
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 542 GWTGKNCTQ-------RAARDRKTCSVLVEESE----RCAEGM----------------C 574
G TG+ C + ++ TC+V + +C G C
Sbjct: 1298 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1357
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
NGGTC+ G + GTC P++ P + C
Sbjct: 1358 LNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCL 1415
Query: 635 CREGRTGALCEL 646
C G LC +
Sbjct: 1416 CPAKFNGLLCHI 1427
Score = 101 bits (243), Expect = 1e-20
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 41/336 (12%)
Query: 205 DNCEKPVCKEGCHP---THGRC-DRPG--DCDCRPGWRGELC----SQCQPYPGCKHGYC 254
D+C PV P +G C D+ G C C PG+ GE C ++C P G
Sbjct: 1223 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQ 1282
Query: 255 NG----SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAPDQYFCRCAEGF 307
N + + C C G C+ +N C +PC++GGTC NTA + C+C GF
Sbjct: 1283 NCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPCKNGGTCAVASNTARG-FICKCPAGF 1340
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--PCLH 365
G CE C C +G ++G R TC C + G G PC +
Sbjct: 1341 EGATCENDARTCGSLRCLNGGTCISGP-RSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 1399
Query: 366 GASCRDHLDG--FTCECADGWTGPACA---EDVDECSGRSMTEGALGPCVNAAACNNTAG 420
+C + + C C + G C +GR + + C AG
Sbjct: 1400 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
Query: 421 GYSCA--C---LAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C+ C GW G DC N +D C C D HC AG C D
Sbjct: 1460 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG--CLFD 1517
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
DC G+C L + Y C FS +C+
Sbjct: 1518 GFDCQRAE----GQCNPLYDQY---CKDHFSDGHCD 1546
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 311 bits (764), Expect = 7e-84
Identities = 178/549 (32%), Positives = 239/549 (43%), Gaps = 66/549 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH--GRCD---RPGDCDCRPGWRG 237
DK Y C C PG+ G C + + +P H G C+ C C G+
Sbjct: 657 DKIDGYECA------CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C HG C S + C CD W G CD + N C ++ PC +GGTC
Sbjct: 711 PTCLSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTC 768
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ Y C C EGFSG +C+ N CA PC + GTC G+ C C + G
Sbjct: 769 KDMTSG-YVCTCREGFSGPNCQTNINECASNPCLNQGTC--IDDVAGYKCNCLLPYTGAT 825
Query: 351 XXXXXXXXASGPCLHGASCRDHLD--GFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
A PC +G CR D F+C C GW G C D++EC L P
Sbjct: 826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--------VLSP 877
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGY 467
C + A+C NT GGY C C AG++GR+CET++DDC C +G +C D ++ C C G+
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGF 937
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C D+++CA PC NG C D +++Y C CP GFSG +CE++ C S C NG
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGT 997
Query: 528 CYTAQSDYYCHCAPGWTGK------------------NCTQRAARDRKTCSV------LV 563
C + + C C PG+TG C R TC
Sbjct: 998 CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Query: 564 EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXXQ 617
C C NGG C + +R D Q
Sbjct: 1058 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ 1117
Query: 618 AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
GG C+ + C C+ G TG+ CE +D C SPC+NG C G + C+CVAG+
Sbjct: 1118 HGGLCVDAG--NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Query: 678 TGETCAVRV 686
G C+ +
Sbjct: 1176 HGVNCSEEI 1184
Score = 310 bits (761), Expect = 2e-83
Identities = 167/531 (31%), Positives = 241/531 (45%), Gaps = 55/531 (10%)
Query: 178 CRPRDDKFGHYSCTPDGD-KH---CLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGD 228
C P + G +C P GD H CLPG+ G NCE+ + C G C +
Sbjct: 222 CSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
Query: 229 CDCRPGWRGELCS----QCQPYP-GCKH-GYCNGS--SWDCTCDTNWGGILCDQDLNYCG 280
C C P W G+ C+ +CQ P C++ G C+ + ++C C W G C ++++ C
Sbjct: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFT 339
+ C HG TC + ++C C G +G+ C +++ C PC G+ C
Sbjct: 341 S-AACFHGATCHDRVA-SFYCECPHGRTGLLC-HLNDACISNPCNEGSNCDTNPVNGKAI 397
Query: 340 CTCDRGWGGXXXXXXXXXXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
CTC G+ G + G PC H C + L F C+C G+TGP C DV+EC
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC- 456
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLV 456
PC N A C + G + C C+ G+ G CE N D+C + CLH C+D +
Sbjct: 457 -------VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI 509
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
++F C C G+ G C DVD+CA PC NG +C+D N Y C+C G++GT+CE D D
Sbjct: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C PC G +C + + C C PG+TG +C C+ C +
Sbjct: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNI--------------NECSSQPCRH 614
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
GGTC + ++ + GTCL G+ C C
Sbjct: 615 GGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD-----SGTCLDKI--DGYECACE 667
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G TG++C +++D C +PC NGG C G + C C G+ TC V+
Sbjct: 668 PGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 306 bits (751), Expect = 3e-82
Identities = 170/531 (32%), Positives = 234/531 (44%), Gaps = 54/531 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP-THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGC 249
C G+ C V + +P HG C + CDC PGW G C ++C+ P
Sbjct: 704 CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
Query: 250 KHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
G C S + CTC + G C ++N C ++ PC + GTC + Y C C +
Sbjct: 764 NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLNQGTCIDDVAG-YKCNCLLPY 821
Query: 308 SGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+G CE V PCAP PC +G C + F+C C GW G PC HG
Sbjct: 822 TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHG 881
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDEC------SGRSMTEG---------------- 404
ASC++ G+ C C G++G C D+D+C +G S T+G
Sbjct: 882 ASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTF 941
Query: 405 --------ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDL 455
A PC N A C + Y+C C AG++G CE N DCT C +G TC+D
Sbjct: 942 CEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDG 1001
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
++ F C C G+ G C DV++C +PC +GG C D +YRC CP G++G NC++
Sbjct: 1002 INSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH 1061
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C SPC NG C+ + Y C C GWTG C + +C V + +C
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV----SCEVAAQRQGVDVARLCQ 1117
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GG CV + G+ S Q G TC + G++C C
Sbjct: 1118 HGGLCV-DAGN---THHCRCQAGYTGSYCEDLVDECSPSPCQNGATC--TDYLGGYSCKC 1171
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
G G C +D C S PC+NGG C+ + C C G G C + V
Sbjct: 1172 VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1222
Score = 304 bits (746), Expect = 1e-81
Identities = 181/569 (31%), Positives = 243/569 (42%), Gaps = 73/569 (12%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH----CLPGWQGDNCEKPVCKEGCHPT 219
+C Y T C D HY DG C PG+ G +CE + + P
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Query: 220 H--GRC-DRPGD--CDCRPGWRGELCS----QCQPYPGCKHGYCNGS--SWDCTCDTNWG 268
G C DR C C G G C C P C G C ++C C+ +
Sbjct: 613 RHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT 671
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
G +C+ +++ C + PC +GGTCE+ + + CRC EG+ C N C PC HG
Sbjct: 672 GSMCNINIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP- 387
C + G+ C CD GW G S PC++G +C+D G+ C C +G++GP
Sbjct: 730 CR--DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
Query: 388 ------ACAED--------VDECSGRSMT----------EGALGPCV-----NAAACNNT 418
CA + +D+ +G E L PC N C +
Sbjct: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Query: 419 AG--GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
+SC C GW G+ CE ++++C C HGA+C + + C C AGY+GR C D
Sbjct: 848 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+DDC P PC NGG C D +N C C GF GT CE+D + CA PC NGA C Y
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 967
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G++G +C + C E C NGGTCV S+
Sbjct: 968 TCTCPAGFSGIHCE--------------NNTPDCTESSCFNGGTCVDGINSF----TCLC 1009
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
S GGTC + C C +G TG C+ + C SSP
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGC--GSYRCTCPQGYTGPNCQNLVHWCDSSP 1067
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NGG+C + CEC +GWTG C V
Sbjct: 1068 CKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
Score = 303 bits (745), Expect = 1e-81
Identities = 163/497 (32%), Positives = 229/497 (46%), Gaps = 44/497 (8%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
CL G+ G CE V C C D+ G+ C C PG+ G C +C P
Sbjct: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
+G C + + C C T + G LC D++ C + PC++G C + P+ Y C C EG
Sbjct: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLD-GPNTYTCVCTEG 557
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
++G CE + C P PC +G+C T FTC C G+ G +S PC HG
Sbjct: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRHG 615
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+C+D + + C C G TGP C ++D+C A PC ++ C + GY CAC
Sbjct: 616 GTCQDRDNAYLCFCLKGTTGPNCEINLDDC--------ASSPC-DSGTCLDKIDGYECAC 666
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C N+D+C G C +G TC D ++ F C C GY TC +V++C PC
Sbjct: 667 EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
+G C D LN Y+C C G+SGTNC+ + + C +PC NG C S Y C C G++G
Sbjct: 727 HGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSG 785
Query: 546 KNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXX 605
NC CA C N GTC+ + ++ +
Sbjct: 786 PNCQTNI--------------NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCE---- 827
Query: 606 XXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG 665
+ GG C S ++C C G G CE+ ++ C SPCR+G C
Sbjct: 828 VVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNT 887
Query: 666 SGWWMCECVAGWTGETC 682
G + C C AG++G C
Sbjct: 888 HGGYRCHCQAGYSGRNC 904
Score = 291 bits (713), Expect = 1e-77
Identities = 170/534 (31%), Positives = 222/534 (41%), Gaps = 61/534 (11%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGD 228
CR +D + +SC C GWQG CE + C+ G C THG
Sbjct: 844 CRQSED-YESFSCV------CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR---- 892
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C+ G+ G C C+P P G C ++ C C + G C++D+N C +
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS- 951
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+PC++G C + D Y C C GFSG+ CE C C +G + G FTC C
Sbjct: 952 DPCRNGANCTDCV-DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLC 1009
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
G+ G S PCLHG +C+D + C C G+TGP C V C
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS---- 1065
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-----------TGQCLHGAT 451
PC N C T Y C C +GWTG C+ C C HG
Sbjct: 1066 ----SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1121
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D + HC C AGY G C VD+C+P PC NG C D L Y C C G+ G NC
Sbjct: 1122 CVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Query: 512 DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
++ D C PC NG C + Y C C G G +C C+ V+ R +
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV----DDCNPPVDPVSRSPK 1237
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C N GTCV + G + + A GT +
Sbjct: 1238 --CFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNECLSNPCDARGTQNCVQRVNDF 1291
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSG---WWMCECVAGWTGETC 682
C CR G TG CE ++ C PC+NGG C S ++C+C AG+ G TC
Sbjct: 1292 HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATC 1345
Score = 289 bits (709), Expect = 3e-77
Identities = 159/505 (31%), Positives = 227/505 (44%), Gaps = 48/505 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG--DCDCRPGWRGELC----SQCQPY 246
C G+ G C + V C G +P G+C + G +C C G+ G C ++C
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 247 PGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P C + C C + G+ C+ + + C + PC H G C + +++ C C
Sbjct: 460 PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECAS-SPCLHNGRCLDKI-NEFQCECP 517
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF+G C+ + CA PC +G L G +TC C G+ G PC
Sbjct: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTCVCTEGYTGTHCEVDIDECDPDPCH 576
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC+D + FTC C G+TG C +++ECS + PC + C + Y C
Sbjct: 577 YG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQ--------PCRHGGTCQDRDNAYLC 627
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
CL G TG +CE N+DDC TC+D +D + CAC GY G C++++D+CA PC
Sbjct: 628 FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPC 687
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C D +N + C CP G+ C + + C +PC +G AC + + Y C C PGW+
Sbjct: 688 HNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKCDCDPGWS 746
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G NC + +E C C NGGTC + +
Sbjct: 747 GTNCD-------------INNNE-CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI 792
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
GTC+ G+ C C TGA CE+ L C SPCRNGG C
Sbjct: 793 NECASNPCLNQ----GTCIDDV--AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
Query: 665 GSGW--WMCECVAGWTGETCAVRVS 687
+ + C C GW G+TC V ++
Sbjct: 847 SEDYESFSCVCPTGWQGQTCEVDIN 871
Score = 277 bits (680), Expect = 1e-73
Identities = 167/513 (32%), Positives = 221/513 (43%), Gaps = 50/513 (9%)
Query: 197 HCLPGWQGDNCEKPV--CKEG-CHPTHGRCD---RPGDCDCRPGWRGELC----SQCQPY 246
HC G+ G NCE + C+ CH G C CDC PG+RG C ++C
Sbjct: 894 HCQAGYSGRNCETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 247 PGCKHGY-CNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P C++G C S+ CTC + GI C+ + C T C +GGTC + + + C C
Sbjct: 953 P-CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGI-NSFTCLC 1009
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
GF+G C+ N C QPC HG G + CTC +G+ G S PC
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCG-SYRCTCPQGYTGPNCQNLVHWCDSSPC 1068
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGG 421
+G C + CEC GWTG C C + +G C + C +
Sbjct: 1069 KNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNT 1128
Query: 422 YSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C AG+TG CE VD+C+ C +GATC D + + C C AGY G CS ++D+C
Sbjct: 1129 HHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECL 1188
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-------AGSP-CGNGAACYTAQ 532
PC NGG C+DL N Y+C CP G G +CE + D C + SP C N C
Sbjct: 1189 SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT--CVREEGSWRXX 590
Y C C PG+ G+ C + C C GT CV+ +
Sbjct: 1249 GGYSCTCPPGFVGERCEG--------------DVNECLSNPCDARGTQNCVQRVNDFHCE 1294
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-LPSALPPGWACGCREGRTGALCELSLD 649
+S + GGTC + S G+ C C G GA CE
Sbjct: 1295 CRAGHTGRRCESVINGCKGKPC----KNGGTCAVASNTARGFICKCPAGFEGATCENDAR 1350
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CGS C NGG C+ G C C+ +TG C
Sbjct: 1351 TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1383
Score = 254 bits (621), Expect = 2e-66
Identities = 151/466 (32%), Positives = 200/466 (42%), Gaps = 45/466 (9%)
Query: 236 RGELCSQCQPYPGCKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
RG CSQ P C +G C ++ C C + G C QD N C PC++ GTC
Sbjct: 20 RGPRCSQ--PGETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPC-LSTPCKNAGTCH 75
Query: 292 --ENTAPDQYFCRCAEGFSGVDC-ERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWG 347
+ Y C CA GFSG C +DN C PC +G TC L T + C C GW
Sbjct: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTE-YKCRCPPGWS 134
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG 407
G AS PC +G C + C C + GP C +DV+EC + G
Sbjct: 135 GKSCQQADPC-ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKP------G 187
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFH-CACAA 465
C + C+N G Y C C A TG +CE C+ C +G TC D H CAC
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--CG 523
G+ G+ C ++DDC C NGG CVD +N Y C CP ++G C +D D C P C
Sbjct: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NG C+ Y C C GWTG++C+ E + CA C +G TC
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCS--------------ENIDDCASAACFHGATC--- 350
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
R G C + + C C G TG
Sbjct: 351 --HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPA 408
Query: 644 CELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C +D C G++PC + G+C+ G + C+C+ G+TG C + V+
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN 454
Score = 251 bits (615), Expect = 8e-66
Identities = 146/509 (28%), Positives = 214/509 (42%), Gaps = 51/509 (10%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRC---DRPGDCDCRPGWRGELCSQ----CQPYPG 248
C PGW G +C++ P C G+C + C C P + G C Q C PG
Sbjct: 129 CPPGWSGKSCQQADPCASNPC-ANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPG 187
Query: 249 -CKH-GYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H G C+ S+ C C G C++ C + PCQ+GGTC T + C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-SPSPCQNGGTCRPTGDVTHECACL 246
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
GF+G +CE + C C +G + G + C C W G P
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNA 305
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C + G+ C C +GWTG C+E++D+C A C + A C++ +
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC--------ASAACFHGATCHDRVASF 357
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATC--IDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G TG C N + C G+ C + C C +GY G CS DVD+C+
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
PC + G+C++ L ++ C C G++G CE D + C +PC N A C ++ C
Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCI 477
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
C PG+ G +C ++ CA C + G C+ + ++
Sbjct: 478 CMPGYEGVHCE--------------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH 523
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRN 658
+ G CL P + C C EG TG CE+ +D C PC
Sbjct: 524 LCQ----YDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHY 577
Query: 659 GGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G C G + C C G+TG C ++
Sbjct: 578 GS-CKDGVATFTCLCRPGYTGHHCETNIN 605
Score = 248 bits (608), Expect = 6e-65
Identities = 145/500 (29%), Positives = 216/500 (43%), Gaps = 48/500 (9%)
Query: 203 QGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCSQCQPYPG--CKH-GYCNG 256
+G C +P E C G+C+ C C + G C P CK+ G C+
Sbjct: 20 RGPRCSQP--GETCL-NGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 257 ------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
+ + C+C + G LC L+ PC++GGTC+ +Y CRC G+SG
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 311 DCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP--CLHGAS 368
C++ D PCA PCA+G L + C C + G P C HG +
Sbjct: 137 SCQQAD-PCASNPCANGGQCLPFEA-SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGT 194
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACL 427
C + + + C C TGP C CS PC N C T + CACL
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSP--------SPCQNGGTCRPTGDVTHECACL 246
Query: 428 AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPC 484
G+TG++CE N+DDC G C +G C+D V+ ++C C + G+ C+ DVD+C P C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C + Y C+C G++G +C ++ D CA + C +GA C+ + +YC C G T
Sbjct: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G +L ++ C C G C + +
Sbjct: 367 G---------------LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
+ G C+ + + C C +G TG CE+ ++ C S+PC+N C+
Sbjct: 412 DVDECSLGANPCEHAGKCINTL--GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 665 GSGWWMCECVAGWTGETCAV 684
G + C C+ G+ G C V
Sbjct: 470 QIGEFQCICMPGYEGVHCEV 489
Score = 237 bits (581), Expect = 1e-61
Identities = 165/552 (29%), Positives = 226/552 (40%), Gaps = 89/552 (16%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDK----HCLPGWQGDNCEKPV------ 211
CQ Y C T CRP G SCT DG CLPG++G CE+ +
Sbjct: 895 CQAGYSGRNCETDIDDCRPNPCHNGG-SCT-DGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 212 -CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYC-NG-------SSWDCT 262
C+ G + T C C C G+ G C P C C NG +S+ C
Sbjct: 953 PCRNGANCTD--CVDSYTCTCPAGFSGIHCENNTP--DCTESSCFNGGTCVDGINSFTCL 1008
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C D+N C + +PC HGGTC++ Y C C +G++G +C+ + + C
Sbjct: 1009 CPPGFTGSYCQHDVNECDS-QPCLHGGTCQDGC-GSYRCTCPQGYTGPNCQNLVHWCDSS 1066
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXX----------XXXXXXXXASGPCLHGASCRDH 372
PC +G T+ + C C GW G + C HG C D
Sbjct: 1067 PCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ C C G+TG C + VDECS PC N A C + GGYSC C+AG+ G
Sbjct: 1126 GNTHHCRCQAGYTGSYCEDLVDECSP--------SPCQNGATCTDYLGGYSCKCVAGYHG 1177
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR--------P 483
+C +D+C C +G TC+DL + + C+C G G C ++VDDC P
Sbjct: 1178 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK 1237
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-GNGAA-CYTAQSDYYCHCAP 541
C N G CVD + Y C CP GF G CE D + C +PC G C +D++C C
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 542 GWTGKNCTQ-------RAARDRKTCSVLVEESE----RCAEGM----------------C 574
G TG+ C + ++ TC+V + +C G C
Sbjct: 1298 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1357
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
NGGTC+ G + GTC P++ P + C
Sbjct: 1358 LNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCL 1415
Query: 635 CREGRTGALCEL 646
C G LC +
Sbjct: 1416 CPAKFNGLLCHI 1427
Score = 101 bits (243), Expect = 1e-20
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 41/336 (12%)
Query: 205 DNCEKPVCKEGCHP---THGRC-DRPG--DCDCRPGWRGELC----SQCQPYPGCKHGYC 254
D+C PV P +G C D+ G C C PG+ GE C ++C P G
Sbjct: 1223 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQ 1282
Query: 255 NG----SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAPDQYFCRCAEGF 307
N + + C C G C+ +N C +PC++GGTC NTA + C+C GF
Sbjct: 1283 NCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPCKNGGTCAVASNTARG-FICKCPAGF 1340
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--PCLH 365
G CE C C +G ++G R TC C + G G PC +
Sbjct: 1341 EGATCENDARTCGSLRCLNGGTCISGP-RSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 1399
Query: 366 GASCRDHLDG--FTCECADGWTGPACA---EDVDECSGRSMTEGALGPCVNAAACNNTAG 420
+C + + C C + G C +GR + + C AG
Sbjct: 1400 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
Query: 421 GYSCA--C---LAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C+ C GW G DC N +D C C D HC AG C D
Sbjct: 1460 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG--CLFD 1517
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
DC G+C L + Y C FS +C+
Sbjct: 1518 GFDCQRAE----GQCNPLYDQY---CKDHFSDGHCD 1546
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 311 bits (764), Expect = 7e-84
Identities = 178/549 (32%), Positives = 239/549 (43%), Gaps = 66/549 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH--GRCD---RPGDCDCRPGWRG 237
DK Y C C PG+ G C + + +P H G C+ C C G+
Sbjct: 169 DKIDGYECA------CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 222
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C HG C S + C CD W G CD + N C ++ PC +GGTC
Sbjct: 223 PTCLSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTC 280
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ Y C C EGFSG +C+ N CA PC + GTC G+ C C + G
Sbjct: 281 KDMTSG-YVCTCREGFSGPNCQTNINECASNPCLNQGTC--IDDVAGYKCNCLLPYTGAT 337
Query: 351 XXXXXXXXASGPCLHGASCRDHLD--GFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
A PC +G CR D F+C C GW G C D++EC L P
Sbjct: 338 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--------VLSP 389
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGY 467
C + A+C NT GGY C C AG++GR+CET++DDC C +G +C D ++ C C G+
Sbjct: 390 CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGF 449
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C D+++CA PC NG C D +++Y C CP GFSG +CE++ C S C NG
Sbjct: 450 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGT 509
Query: 528 CYTAQSDYYCHCAPGWTGK------------------NCTQRAARDRKTCSV------LV 563
C + + C C PG+TG C R TC
Sbjct: 510 CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 569
Query: 564 EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXXQ 617
C C NGG C + +R D Q
Sbjct: 570 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ 629
Query: 618 AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
GG C+ + C C+ G TG+ CE +D C SPC+NG C G + C+CVAG+
Sbjct: 630 HGGLCVDAG--NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 687
Query: 678 TGETCAVRV 686
G C+ +
Sbjct: 688 HGVNCSEEI 696
Score = 306 bits (751), Expect = 3e-82
Identities = 170/531 (32%), Positives = 234/531 (44%), Gaps = 54/531 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP-THGRCDRPGD---CDCRPGWRGELC----SQCQPYPGC 249
C G+ C V + +P HG C + CDC PGW G C ++C+ P
Sbjct: 216 CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 275
Query: 250 KHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
G C S + CTC + G C ++N C ++ PC + GTC + Y C C +
Sbjct: 276 NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLNQGTCIDDVAG-YKCNCLLPY 333
Query: 308 SGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+G CE V PCAP PC +G C + F+C C GW G PC HG
Sbjct: 334 TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHG 393
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDEC------SGRSMTEG---------------- 404
ASC++ G+ C C G++G C D+D+C +G S T+G
Sbjct: 394 ASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTF 453
Query: 405 --------ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDL 455
A PC N A C + Y+C C AG++G CE N DCT C +G TC+D
Sbjct: 454 CEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDG 513
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
++ F C C G+ G C DV++C +PC +GG C D +YRC CP G++G NC++
Sbjct: 514 INSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH 573
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C SPC NG C+ + Y C C GWTG C + +C V + +C
Sbjct: 574 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV----SCEVAAQRQGVDVARLCQ 629
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GG CV + G+ S Q G TC + G++C C
Sbjct: 630 HGGLCV-DAGN---THHCRCQAGYTGSYCEDLVDECSPSPCQNGATC--TDYLGGYSCKC 683
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
G G C +D C S PC+NGG C+ + C C G G C + V
Sbjct: 684 VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 734
Score = 304 bits (746), Expect = 1e-81
Identities = 181/569 (31%), Positives = 243/569 (42%), Gaps = 73/569 (12%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH----CLPGWQGDNCEKPVCKEGCHPT 219
+C Y T C D HY DG C PG+ G +CE + + P
Sbjct: 65 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 124
Query: 220 H--GRC-DRPGD--CDCRPGWRGELCS----QCQPYPGCKHGYCNGS--SWDCTCDTNWG 268
G C DR C C G G C C P C G C ++C C+ +
Sbjct: 125 RHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT 183
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
G +C+ +++ C + PC +GGTCE+ + + CRC EG+ C N C PC HG
Sbjct: 184 GSMCNINIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 241
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP- 387
C + G+ C CD GW G S PC++G +C+D G+ C C +G++GP
Sbjct: 242 CR--DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 299
Query: 388 ------ACAED--------VDECSGRSMT----------EGALGPCV-----NAAACNNT 418
CA + +D+ +G E L PC N C +
Sbjct: 300 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 359
Query: 419 AG--GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
+SC C GW G+ CE ++++C C HGA+C + + C C AGY+GR C D
Sbjct: 360 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 419
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+DDC P PC NGG C D +N C C GF GT CE+D + CA PC NGA C Y
Sbjct: 420 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 479
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G++G +C + C E C NGGTCV S+
Sbjct: 480 TCTCPAGFSGIHCE--------------NNTPDCTESSCFNGGTCVDGINSF----TCLC 521
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
S GGTC + C C +G TG C+ + C SSP
Sbjct: 522 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGC--GSYRCTCPQGYTGPNCQNLVHWCDSSP 579
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NGG+C + CEC +GWTG C V
Sbjct: 580 CKNGGKCWQTHTQYRCECPSGWTGLYCDV 608
Score = 291 bits (713), Expect = 1e-77
Identities = 170/534 (31%), Positives = 222/534 (41%), Gaps = 61/534 (11%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGD 228
CR +D + +SC C GWQG CE + C+ G C THG
Sbjct: 356 CRQSED-YESFSCV------CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR---- 404
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C+ G+ G C C+P P G C ++ C C + G C++D+N C +
Sbjct: 405 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS- 463
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+PC++G C + D Y C C GFSG+ CE C C +G + G FTC C
Sbjct: 464 DPCRNGANCTDCV-DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLC 521
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
G+ G S PCLHG +C+D + C C G+TGP C V C
Sbjct: 522 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS---- 577
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-----------TGQCLHGAT 451
PC N C T Y C C +GWTG C+ C C HG
Sbjct: 578 ----SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 633
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D + HC C AGY G C VD+C+P PC NG C D L Y C C G+ G NC
Sbjct: 634 CVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS 693
Query: 512 DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
++ D C PC NG C + Y C C G G +C C+ V+ R +
Sbjct: 694 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV----DDCNPPVDPVSRSPK 749
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C N GTCV + G + + A GT +
Sbjct: 750 --CFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNECLSNPCDARGTQNCVQRVNDF 803
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSG---WWMCECVAGWTGETC 682
C CR G TG CE ++ C PC+NGG C S ++C+C AG+ G TC
Sbjct: 804 HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATC 857
Score = 287 bits (703), Expect = 2e-76
Identities = 146/444 (32%), Positives = 208/444 (46%), Gaps = 35/444 (7%)
Query: 242 QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
+C P +G C + + C C T + G LC D++ C + PC++G C + P+ Y
Sbjct: 5 ECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLD-GPNTY 62
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C EG++G CE + C P PC +G+C T FTC C G+ G +
Sbjct: 63 TCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVAT--FTCLCRPGYTGHHCETNINECS 120
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC HG +C+D + + C C G TGP C ++D+C A PC ++ C +
Sbjct: 121 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC--------ASSPC-DSGTCLDKI 171
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
GY CAC G+TG C N+D+C G C +G TC D ++ F C C GY TC +V++
Sbjct: 172 DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNE 231
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C PC +G C D LN Y+C C G+SGTNC+ + + C +PC NG C S Y C
Sbjct: 232 CNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 290
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
C G++G NC CA C N GTC+ + ++
Sbjct: 291 CREGFSGPNCQTNI--------------NECASNPCLNQGTCIDDVAGYKCNCLLPYTGA 336
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRN 658
+ + GG C S ++C C G G CE+ ++ C SPCR+
Sbjct: 337 TCE----VVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRH 392
Query: 659 GGRCVGGSGWWMCECVAGWTGETC 682
G C G + C C AG++G C
Sbjct: 393 GASCQNTHGGYRCHCQAGYSGRNC 416
Score = 277 bits (680), Expect = 1e-73
Identities = 167/513 (32%), Positives = 221/513 (43%), Gaps = 50/513 (9%)
Query: 197 HCLPGWQGDNCEKPV--CKEG-CHPTHGRCD---RPGDCDCRPGWRGELC----SQCQPY 246
HC G+ G NCE + C+ CH G C CDC PG+RG C ++C
Sbjct: 406 HCQAGYSGRNCETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 464
Query: 247 PGCKHGY-CNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P C++G C S+ CTC + GI C+ + C T C +GGTC + + + C C
Sbjct: 465 P-CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGI-NSFTCLC 521
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
GF+G C+ N C QPC HG G + CTC +G+ G S PC
Sbjct: 522 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCG-SYRCTCPQGYTGPNCQNLVHWCDSSPC 580
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGG 421
+G C + CEC GWTG C C + +G C + C +
Sbjct: 581 KNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNT 640
Query: 422 YSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C AG+TG CE VD+C+ C +GATC D + + C C AGY G CS ++D+C
Sbjct: 641 HHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECL 700
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-------AGSP-CGNGAACYTAQ 532
PC NGG C+DL N Y+C CP G G +CE + D C + SP C N C
Sbjct: 701 SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQV 760
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT--CVREEGSWRXX 590
Y C C PG+ G+ C + C C GT CV+ +
Sbjct: 761 GGYSCTCPPGFVGERCEG--------------DVNECLSNPCDARGTQNCVQRVNDFHCE 806
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-LPSALPPGWACGCREGRTGALCELSLD 649
+S + GGTC + S G+ C C G GA CE
Sbjct: 807 CRAGHTGRRCESVINGCKGKPC----KNGGTCAVASNTARGFICKCPAGFEGATCENDAR 862
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CGS C NGG C+ G C C+ +TG C
Sbjct: 863 TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 895
Score = 265 bits (649), Expect = 6e-70
Identities = 135/406 (33%), Positives = 187/406 (46%), Gaps = 34/406 (8%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + +++ C C GF+G C+ + CA PC +G L G +TC C
Sbjct: 10 PCLHNGRCLDKI-NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTCVCT 67
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G+ G PC +G SC+D + FTC C G+TG C +++ECS +
Sbjct: 68 EGYTGTHCEVDIDECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQ---- 122
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCAC 463
PC + C + Y C CL G TG +CE N+DDC TC+D +D + CAC
Sbjct: 123 ----PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECAC 178
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C++++D+CA PC NGG C D +N + C CP G+ C + + C +PC
Sbjct: 179 EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 238
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
+GA C + + Y C C PGW+G NC + +E C C NGGTC
Sbjct: 239 HGA-CRDSLNGYKCDCDPGWSGTNCD-------------INNNE-CESNPCVNGGTCKDM 283
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
+ + GTC+ G+ C C TGA
Sbjct: 284 TSGYVCTCREGFSGPNCQTNINECASNPCLNQ----GTCIDDVA--GYKCNCLLPYTGAT 337
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRVS 687
CE+ L C SPCRNGG C + + C C GW G+TC V ++
Sbjct: 338 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 383
Score = 237 bits (581), Expect = 1e-61
Identities = 165/552 (29%), Positives = 226/552 (40%), Gaps = 89/552 (16%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDK----HCLPGWQGDNCEKPV------ 211
CQ Y C T CRP G SCT DG CLPG++G CE+ +
Sbjct: 407 CQAGYSGRNCETDIDDCRPNPCHNGG-SCT-DGINTAFCDCLPGFRGTFCEEDINECASD 464
Query: 212 -CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYC-NG-------SSWDCT 262
C+ G + T C C C G+ G C P C C NG +S+ C
Sbjct: 465 PCRNGANCTD--CVDSYTCTCPAGFSGIHCENNTP--DCTESSCFNGGTCVDGINSFTCL 520
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C D+N C + +PC HGGTC++ Y C C +G++G +C+ + + C
Sbjct: 521 CPPGFTGSYCQHDVNECDS-QPCLHGGTCQDGC-GSYRCTCPQGYTGPNCQNLVHWCDSS 578
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXX----------XXXXXXXXASGPCLHGASCRDH 372
PC +G T+ + C C GW G + C HG C D
Sbjct: 579 PCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 637
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ C C G+TG C + VDECS PC N A C + GGYSC C+AG+ G
Sbjct: 638 GNTHHCRCQAGYTGSYCEDLVDECSP--------SPCQNGATCTDYLGGYSCKCVAGYHG 689
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR--------P 483
+C +D+C C +G TC+DL + + C+C G G C ++VDDC P
Sbjct: 690 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK 749
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-GNGAA-CYTAQSDYYCHCAP 541
C N G CVD + Y C CP GF G CE D + C +PC G C +D++C C
Sbjct: 750 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 809
Query: 542 GWTGKNCTQ-------RAARDRKTCSVLVEESE----RCAEGM----------------C 574
G TG+ C + ++ TC+V + +C G C
Sbjct: 810 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 869
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
NGGTC+ G + GTC P++ P + C
Sbjct: 870 LNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCL 927
Query: 635 CREGRTGALCEL 646
C G LC +
Sbjct: 928 CPAKFNGLLCHI 939
Score = 169 bits (411), Expect = 4e-41
Identities = 80/251 (31%), Positives = 114/251 (45%), Gaps = 23/251 (9%)
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
N D+C CLH C+D +++F C C G+ G C DVD+CA PC NG +C+D N
Sbjct: 2 NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT 61
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
Y C+C G++GT+CE D D C PC G+ C + + C C PG+TG +C
Sbjct: 62 YTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNI---- 116
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C+ C +GGTC + ++ +
Sbjct: 117 ----------NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS-- 164
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
GTCL G+ C C G TG++C +++D C +PC NGG C G + C C G
Sbjct: 165 ---GTCLDKI--DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEG 219
Query: 677 WTGETCAVRVS 687
+ TC V+
Sbjct: 220 YHDPTCLSEVN 230
Score = 120 bits (290), Expect = 2e-26
Identities = 68/216 (31%), Positives = 97/216 (44%), Gaps = 28/216 (12%)
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ D+CA PC + G C+D +N ++C CP GF+G C+ D D CA +PC NGA C +
Sbjct: 1 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN 60
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXX 590
Y C C G+TG +C D C + + C G C +G TC+ G
Sbjct: 61 TYTCVCTEGYTGTHCEV----DIDEC-----DPDPCHYGSCKDGVATFTCLCRPG----- 106
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
+ GGTC + C C +G TG CE++LD
Sbjct: 107 --------YTGHHCETNINECSSQPCRHGGTC--QDRDNAYLCFCLKGTTGPNCEINLDD 156
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C SSPC + G C+ + C C G+TG C + +
Sbjct: 157 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINI 191
Score = 101 bits (243), Expect = 1e-20
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 41/336 (12%)
Query: 205 DNCEKPVCKEGCHP---THGRC-DRPG--DCDCRPGWRGELC----SQCQPYPGCKHGYC 254
D+C PV P +G C D+ G C C PG+ GE C ++C P G
Sbjct: 735 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQ 794
Query: 255 NG----SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAPDQYFCRCAEGF 307
N + + C C G C+ +N C +PC++GGTC NTA + C+C GF
Sbjct: 795 NCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPCKNGGTCAVASNTARG-FICKCPAGF 852
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--PCLH 365
G CE C C +G ++G R TC C + G G PC +
Sbjct: 853 EGATCENDARTCGSLRCLNGGTCISGP-RSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 911
Query: 366 GASCRDHLDG--FTCECADGWTGPACA---EDVDECSGRSMTEGALGPCVNAAACNNTAG 420
+C + + C C + G C +GR + + C AG
Sbjct: 912 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 971
Query: 421 GYSCA--C---LAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C+ C GW G DC N +D C C D HC AG C D
Sbjct: 972 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG--CLFD 1029
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
DC G+C L + Y C FS +C+
Sbjct: 1030 GFDCQRAE----GQCNPLYDQY---CKDHFSDGHCD 1058
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 307 bits (754), Expect = 1e-82
Identities = 171/505 (33%), Positives = 224/505 (44%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCE-KPVCKEGCHPTHGRCDRP-------GDCDCRPGWRGELCSQCQP--YP 247
C PGW G+ C+ + C G G C C C G+RG CS P
Sbjct: 67 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 126
Query: 248 GCKHG-YCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C HG C+ + C+C + G C D++ C EPC+HGGTC NT P + C+C
Sbjct: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-PGSFRCQC 185
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
G++G CE PCAP PC + GTC +G + C C G+ G
Sbjct: 186 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT-YDCACLPGFEGQNCEVNVDDCPGHR 244
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
CL+G +C D ++ + C+C WTG C EDVDEC + C N C NT GG+
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP------NACHNGGTCFNTLGGH 298
Query: 423 SCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
SC C+ GWTG C N+DDC T C HGATC D V F+CAC G G C LD D C
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVS 357
Query: 482 RPCTNGGEC-VDLLNAYR-CICPVGFSGTNCEDDRDHCA--GSPCGNGAACYTAQSDYYC 537
PC C + +N C CP GF+G C+ D D C+ +PC + C Q + C
Sbjct: 358 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 417
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG C + C G C N TC+ G +
Sbjct: 418 QCGRGYTGPRCE--------------TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 463
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ GG C G++C C G +G+ C+L +D C S+PCR
Sbjct: 464 TYCEVDIDECQSSPCVN----GGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCR 517
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG +CV + C C G+ G C
Sbjct: 518 NGAKCVDQPDGYECRCAEGFEGTLC 542
Score = 293 bits (720), Expect = 2e-78
Identities = 190/570 (33%), Positives = 252/570 (44%), Gaps = 72/570 (12%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPVCKEGCHP 218
C P Y T C + CR + + G C DK+ C G G NCE + +P
Sbjct: 570 CAPGYTGTRCESQVDECRSQPCRHGG-KCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNP 628
Query: 219 -THGRCDRPG----DCDCRPGWRGELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNW 267
T G C R G DC C+PG+ G LC+ +C P + G C + + C C
Sbjct: 629 CTFGVC-RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
Query: 268 GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER--VDNPCAPQPC- 324
LC + C HEPC HG C + AP + C C G+SG C + + C QPC
Sbjct: 688 LPPLCLPPSHPCA-HEPCSHG-ICYD-APGGFRCVCEPGWSGPRCSQSLARDACESQPCR 744
Query: 325 AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF-TCECADG 383
A GTCS G GF CTC G G + PC HG C C C G
Sbjct: 745 AGGTCSSDGM--GFHCTCPPGVQGRQCELLSPCTPN-PCEHGGRCESAPGQLPVCSCPQG 801
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT 443
W GP C +DVDEC+G + PC C N AG +SC C G+TG C+ +++DC
Sbjct: 802 WQGPRCQQDVDECAGPA-------PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
Query: 444 -GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
CL+G +C D V F C+C G+AG C+ DVD+C PC G C D + ++ C CP
Sbjct: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCP 913
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR----------- 551
G+ G +CE D C+ S C NG C + + C C PG+TG +C
Sbjct: 914 PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLH 973
Query: 552 -----AARDRKTCSVLVEES--------ERCAEGMCANGGTCVREEG------SWRXXXX 592
AA C+ L + + C+ C NGG CV+ W
Sbjct: 974 GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLC 1033
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
++ QAGG C+ C C EGRTG+ CE +D C
Sbjct: 1034 DIRSLPCREAAAQIGVRLEQLC--QAGGQCVDE--DSSHYCVCPEGRTGSHCEQEVDPCL 1089
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ PC++GG C G G +MCEC+ G+ G+ C
Sbjct: 1090 AQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
Score = 291 bits (713), Expect = 1e-77
Identities = 182/546 (33%), Positives = 245/546 (44%), Gaps = 55/546 (10%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSC--TPDGDK-HCLPGWQGDNCEKPV--CKEGC 216
C P Y +C + CR + +C TP + C G+ G CE P C
Sbjct: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP 205
Query: 217 HPTHGRCDRPGD----CDCRPGWRGELCS----QCQPYPGCKHGYC-NG-SSWDCTCDTN 266
G C + GD C C PG+ G+ C C + G C +G ++++C C
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE 265
Query: 267 WGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C +D++ C C +GGTC NT + C C G++G C + + CA C
Sbjct: 266 WTGQFCTEDVDECQLQPNACHNGGTCFNTLGG-HSCVCVNGWTGESCSQNIDDCATAVCF 324
Query: 326 HG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH-LDGFT-CECAD 382
HG TC F C C G G S PC A C + ++G C C
Sbjct: 325 HGATCH--DRVASFYCACPMGKTGLLCHLDDAC-VSNPCHEDAICDTNPVNGRAICTCPP 381
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G+TG AC +DVDECS GA PC + C NT G + C C G+TG CET+V++C
Sbjct: 382 GFTGGACDQDVDECS-----IGA-NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 435
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+G C + ATC+D + F C C AG+ G C +D+D+C PC NGG C D +N + C C
Sbjct: 436 LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC 495
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P GFSG+ C+ D D CA +PC NGA C Y C CA G+ G C R+ CS
Sbjct: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD----RNVDDCSP 551
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
RC +G+ + C R + GG
Sbjct: 552 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP---------------CRHGGK 596
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGET 681
CL L + C C G TG CE+++D C S+PC G C G + C C G+TG
Sbjct: 597 CLD--LVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPL 653
Query: 682 CAVRVS 687
C V ++
Sbjct: 654 CNVEIN 659
Score = 290 bits (712), Expect = 1e-77
Identities = 170/502 (33%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT---HGR-C-DRPGD--CDCRPGWRGELC---SQCQPYP 247
C+ GW G++C + + + C HG C DR C C G G LC C P
Sbjct: 302 CVNGWTGESCSQNI--DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 359
Query: 248 GCKHGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
+ C+ + + CTC + G CDQD++ C PC+H G C NT + C+
Sbjct: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ-GSFLCQ 418
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G++G CE N C PC + L + FTC C G+ G S P
Sbjct: 419 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTCICMAGFTGTYCEVDIDECQSSP 477
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C++G C+D ++GF+C C G++G C DVDEC+ PC N A C + GY
Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST--------PCRNGAKCVDQPDGY 529
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G+ G C+ NVDDC+ H C+D + F CACA GY G C VD+C +
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC +GG+C+DL++ Y C CP G +G NCE + D CA +PC G C + Y C C PG
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPG 648
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C+V + E CA C GG+CV E +R
Sbjct: 649 FTG-----------PLCNVEINE---CASSPCGEGGSCVDGENGFRCLCPPGSL-----P 689
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL--DLCGSSPCRNGG 660
+ G C + P G+ C C G +G C SL D C S PCR GG
Sbjct: 690 PLCLPPSHPCAHEPCSHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
C + C C G G C
Sbjct: 748 TCSSDGMGFHCTCPPGVQGRQC 769
Score = 287 bits (704), Expect = 1e-76
Identities = 165/509 (32%), Positives = 226/509 (44%), Gaps = 58/509 (11%)
Query: 195 DKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS---- 241
D CLPG++G NCE V + C P H RC G +C C P W G+ C+
Sbjct: 221 DCACLPGFEGQNCEVNV--DDC-PGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 276
Query: 242 QCQPYPGCKH--GYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+CQ P H G C + C C W G C Q+++ C T C HG TC +
Sbjct: 277 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDRVA- 334
Query: 298 QYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
++C C G +G+ C +D+ C PC C CTC G+ G
Sbjct: 335 SFYCACPMGKTGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD 393
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+ G PC H C + F C+C G+TGP C DV+EC GPC N A
Sbjct: 394 ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS--------GPCRNQAT 445
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C + G ++C C+AG+TG CE ++D+C + C++G C D V+ F C C +G++G TC
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
LDVD+CA PC NG +CVD + Y C C GF GT C+ + D C+ PC +G C +
Sbjct: 506 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIA 564
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+ C CAPG+TG C + + C C +GG C+ +
Sbjct: 565 SFSCACAPGYTGTRCESQV--------------DECRSQPCRHGGKCLDLVDKYLCRCPS 610
Query: 594 XXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGS 653
+ G C + C C+ G TG LC + ++ C S
Sbjct: 611 GTTGVNCEVNIDDCASNPCTF-----GVCRDGI--NRYDCVCQPGFTGPLCNVEINECAS 663
Query: 654 SPCRNGGRCVGGSGWWMCECVAGWTGETC 682
SPC GG CV G + C C G C
Sbjct: 664 SPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
Score = 271 bits (665), Expect = 7e-72
Identities = 168/519 (32%), Positives = 226/519 (43%), Gaps = 53/519 (10%)
Query: 189 SCTPDGDK--HCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPGD--CDCRPGWRGELC 240
S PDG C PG+QG +C V C+ G HG C + PG C C G+ G LC
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Query: 241 SQ----CQPYPGCKHGYCNGS---SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCEN 293
C P P G C S ++DC C + G C+ +++ C H C +GGTC +
Sbjct: 195 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVD 253
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ Y C+C ++G C + C QP A H + T G +C C GW G
Sbjct: 254 GV-NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
A+ C HGA+C D + F C C G TG C D D C PC
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSN--------PCHED 363
Query: 413 AACN-NTAGGYS-CACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
A C+ N G + C C G+TG C+ +VD+C+ C H C++ F C C GY
Sbjct: 364 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 423
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C DV++C PC N C+D + + CIC GF+GT CE D D C SPC NG
Sbjct: 424 TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 483
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + C C G++G TC + V+E CA C NG CV + +
Sbjct: 484 CKDRVNGFSCTCPSGFSGS-----------TCQLDVDE---CASTPCRNGAKCVDQPDGY 529
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
D G C+ ++C C G TG CE
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHH-----GRCVDGIA--SFSCACAPGYTGTRCESQ 582
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PCR+GG+C+ ++C C +G TG C V +
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI 621
Score = 265 bits (650), Expect = 5e-70
Identities = 200/684 (29%), Positives = 262/684 (38%), Gaps = 91/684 (13%)
Query: 164 LCQPNYYNTTCTTFCRP-RDDKFGHYSC--TPDGDKH-CLPGWQGDNCEKPVCKEGCHP- 218
LC P C P + H C P G + C PGW G C + + ++ C
Sbjct: 682 LCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ 741
Query: 219 ---THGRCDRPG---DCDCRPGWRG---ELCSQCQPYPGCKHG-YCNGSSWD---CTCDT 265
G C G C C PG +G EL S C P P C+HG C + C+C
Sbjct: 742 PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP-CEHGGRCESAPGQLPVCSCPQ 800
Query: 266 NWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C QD++ C PC G C N A + C C G++G C++ N C P PC
Sbjct: 801 GWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSCTCHGGYTGPSCDQDINDCDPNPCL 859
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT 385
+G G F+C+C G+ G S PC G +C DH+ FTC C G+
Sbjct: 860 NGGSCQDGVG-SFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYG 917
Query: 386 GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ 445
G C +D+ +CS S C N C + +SC C G+TG C+ D C +
Sbjct: 918 GFHCEQDLPDCSPSS--------CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 446 -CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
CLHG C F C C + G C VD C+ +PC NGG CV AY C+CP G
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPG 1027
Query: 505 FSGTNCEDDRDHCAGSP----------CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+SG C+ C + C G C S +YC C G TG +C Q
Sbjct: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ---- 1083
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
E + C C +GGTC G + +
Sbjct: 1084 ----------EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC-- 1131
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNGGRCVGGSG 667
Q GG+C+ L + C C G G LCE++ D CG P C + G CV G
Sbjct: 1132 --QHGGSCID--LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVG 1187
Query: 668 WWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAARR 727
+ C C G+TG C ++ RCLC A + R
Sbjct: 1188 GFRCTCPPGYTGLRCEADIN---ECRSGACHAAHTRDCLQDPGGGFRCLCHA--GFSGPR 1242
Query: 728 CLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDG-PGACGVANGTWWWGCNACWCSGG 786
C ++ E+ Q HG RP P G G C A +WG C
Sbjct: 1243 CQTVLSPCES--------QPCQHGGQCRPSPGPGGGLTFTCHCAQP--FWGPR---CERV 1289
Query: 787 VPTCTRLWC--GLPDCLAPNAQPC 808
+C L C G+P P C
Sbjct: 1290 ARSCRELQCPVGVPCQQTPRGPRC 1313
Score = 261 bits (640), Expect = 8e-69
Identities = 151/500 (30%), Positives = 204/500 (40%), Gaps = 47/500 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
C G+ G CE V C G C DR G C C G+ G C +CQ P
Sbjct: 419 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 478
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C + + CTC + + G C D++ C + PC++G C + PD Y CRCAEG
Sbjct: 479 VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAS-TPCRNGAKCVDQ-PDGYECRCAEG 536
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
F G C+R + C+P PC HG C F+C C G+ G S PC HG
Sbjct: 537 FEGTLCDRNVDDCSPDPCHHGRC--VDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG 594
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C D +D + C C G TG C ++D+C+ T G C + Y C C
Sbjct: 595 GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV---------CRDGINRYDCVC 645
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C +++C C G +C+D + F C C G C CA PC+
Sbjct: 646 QPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS 705
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDD--RDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+G C D +RC+C G+SG C RD C PC G C + ++C C PG
Sbjct: 706 HG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+ C E C C +GG C G
Sbjct: 765 QGRQC---------------ELLSPCTPNPCEHGGRCESAPGQ----LPVCSCPQGWQGP 805
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G + + L ++C C G TG C+ ++ C +PC NGG C
Sbjct: 806 RCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 865
Query: 664 GGSGWWMCECVAGWTGETCA 683
G G + C C+ G+ G CA
Sbjct: 866 DGVGSFSCSCLPGFAGPRCA 885
Score = 250 bits (612), Expect = 2e-65
Identities = 138/435 (31%), Positives = 191/435 (43%), Gaps = 38/435 (8%)
Query: 261 CTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERVD 316
C C W G C +D + G PC G C+++ ++ CRC GF G DC D
Sbjct: 65 CLCPPGWVGERCQLEDPCHSG---PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD 121
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDG 375
PC PCAHG G F C+C G+ G G PC HG +C +
Sbjct: 122 -PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 180
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRD 434
F C+C G+TGP C C A PC N C + Y CACL G+ G++
Sbjct: 181 FRCQCPAGYTGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
Query: 435 CETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECV 491
CE NVDDC G +CL+G TC+D V+ ++C C + G+ C+ DVD+C P C NGG C
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF 292
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
+ L + C+C G++G +C + D CA + C +GA C+ + +YC C G TG
Sbjct: 293 NTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTG------ 346
Query: 552 AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXX 611
+L + C C C + R
Sbjct: 347 ---------LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 397
Query: 612 XXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMC 671
+ G C+ + + C C G TG CE ++ C S PCRN C+ G + C
Sbjct: 398 GANPCEHLGRCVNT--QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
Query: 672 ECVAGWTGETCAVRV 686
C+AG+TG C V +
Sbjct: 456 ICMAGFTGTYCEVDI 470
Score = 244 bits (597), Expect = 1e-63
Identities = 157/504 (31%), Positives = 208/504 (41%), Gaps = 51/504 (10%)
Query: 204 GDNCEKPVCKEGCHPTHG-RC----DRPGDCDCRPGWRGELCS---QCQPYPGCKHGYCN 255
G P C +G +G RC R C C PGW GE C C P G C
Sbjct: 35 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ 94
Query: 256 GS------SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S + C C + G C + C PC HG C ++ C C G+ G
Sbjct: 95 SSVVAGTARFSCRCPRGFRGPDCSLP-DPC-LSSPCAHGARCSVGPDGRFLCSCPPGYQG 152
Query: 310 VDCER-VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
C VD +PC HG L T F C C G+ G A PC +G +
Sbjct: 153 RSCRSDVDECRVGEPCRHGGTCL-NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 211
Query: 369 CRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
CR D + C C G+ G C +VD+C G C+N C + Y+C C
Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR--------CLNGGTCVDGVNTYNCQCP 263
Query: 428 AGWTGRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
WTG+ C +VD+C Q C +G TC + + C C G+ G +CS ++DDCA C
Sbjct: 264 PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVC 323
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPG 542
+G C D + ++ C CP+G +G C D D C +PC A C T C C PG
Sbjct: 324 FHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPG 382
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C Q D CS+ C + G CV +GS+ ++
Sbjct: 383 FTGGACDQ----DVDECSI--------GANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET 430
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC 662
QA TCL + C C G TG CE+ +D C SSPC NGG C
Sbjct: 431 --DVNECLSGPCRNQA--TCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 484
Query: 663 VGGSGWWMCECVAGWTGETCAVRV 686
+ C C +G++G TC + V
Sbjct: 485 KDRVNGFSCTCPSGFSGSTCQLDV 508
Score = 241 bits (589), Expect = 1e-62
Identities = 139/420 (33%), Positives = 185/420 (44%), Gaps = 40/420 (9%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCS---LAGT 334
C PC +GG C + C C G+ G C+ +++PC PCA G C +AGT
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 101
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDV 393
R F+C C RG+ G +S PC HGA C DG F C C G+ G +C DV
Sbjct: 102 AR-FSCRCPRGFRGPDCSLPDPCLSS-PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 159
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATC 452
DEC PC + C NT G + C C AG+TG CE C C +G TC
Sbjct: 160 DECRVGE-------PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212
Query: 453 IDLVD-DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
D + CAC G+ G+ C ++VDDC C NGG CVD +N Y C CP ++G C
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 272
Query: 512 DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
+D D C P C NG C+ + C C GWTG++C+Q + C
Sbjct: 273 EDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI--------------DDC 318
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
A +C +G TC R C + +
Sbjct: 319 ATAVCFHGATC-----HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG 373
Query: 630 GWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C C G TG C+ +D C G++PC + GRCV G ++C+C G+TG C V+
Sbjct: 374 RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 433
Score = 219 bits (536), Expect = 3e-56
Identities = 156/536 (29%), Positives = 213/536 (39%), Gaps = 73/536 (13%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRCD---RPGDCDCRPGWRGELCSQ----CQPYPG 248
C PG+ G +CE+ P C G C C CRPG+ G C C P
Sbjct: 912 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
Query: 249 CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C+ + + CTC ++ G C +++C + +PCQ+GG C T +C C G
Sbjct: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWC-SRQPCQNGGRCVQTGA---YCLCPPG 1027
Query: 307 FSGVDCERVDNPCAPQPCAHGT-----CSLAGTT----RGFTCTCDRGWGGXXXXXXXXX 357
+SG C+ PC G C G C C G G
Sbjct: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP 1087
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
+ PC HG +CR ++ G+ CEC G+ G C +DVDEC+ + PC + +C +
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQ--------PCQHGGSCID 1139
Query: 418 TAGGYSCACLAGWTGRDCETNVDDC-------TG-QCLHGATCIDLVDDFHCACAAGYAG 469
Y C+C G G CE N DDC +G +CLH TC+DLV F C C GY G
Sbjct: 1140 LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1199
Query: 470 RTCSLDVDDCAPRPC--TNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
C D+++C C + +C+ D +RC+C GFSG C+ C PC +G
Sbjct: 1200 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGG 1259
Query: 527 ACYTAQS-----DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C + + CHCA + G C +R AR C E C G C
Sbjct: 1260 QCRPSPGPGGGLTFTCHCAQPFWGPRC-ERVARS-------------CRELQCPVGVPCQ 1305
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA----GGTCLPSALPPGWACGCRE 637
+ R S A GG+C P+ L P + C C +
Sbjct: 1306 QTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365
Query: 638 GRTGALCE--LSLDLCGSSPCRNGGRCVGGSGWWMC--ECVA---GWTGETCAVRV 686
G TG CE + P C G C EC + GW G C++ V
Sbjct: 1366 GWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSV 1421
Score = 194 bits (473), Expect = 1e-48
Identities = 143/458 (31%), Positives = 179/458 (39%), Gaps = 61/458 (13%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHY--SCTPDGDKHCLPGWQGDNCEKPV--CKEGC 216
LC+P Y C C R G + P CL + G C+ V C
Sbjct: 949 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 1008
Query: 217 HPTHGRCDRPGD-CDCRPGWRGELCS----QCQPYPG---------CKHG-YC--NGSSW 259
GRC + G C C PGW G LC C+ C+ G C SS
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
Query: 260 DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C G C+Q+++ C +PCQHGGTC Y C C G++G +CE + C
Sbjct: 1069 YCVCPEGRTGSHCEQEVDPC-LAQPCQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDEC 1126
Query: 320 APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLHGASCRDH 372
A QPC HG + R + C+C G G GP CLH +C D
Sbjct: 1127 ASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ GF C C G+TG C D++EC RS GA + GG+ C C AG++G
Sbjct: 1186 VGGFRCTCPPGYTGLRCEADINEC--RS---GACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDD-----FHCACAAGYAGRTCSLDVDDCAPRPCTN 486
C+T + C Q C HG C F C CA + G C C C
Sbjct: 1241 PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPV 1300
Query: 487 GGECVDLLNAYRCICPVGFSGTNCED--------DRDHCAGSPCGNGAACYTA--QSDYY 536
G C RC CP G SG +C CA +PC +G +C A +
Sbjct: 1301 GVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFR 1360
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C CA GWTG C AA V E RC C
Sbjct: 1361 CACAQGWTGPRCEAPAAAPE------VSEEPRCPRAAC 1392
Score = 111 bits (268), Expect = 9e-24
Identities = 113/383 (29%), Positives = 138/383 (36%), Gaps = 58/383 (15%)
Query: 183 DKFGHYSCT-PDGDKHCLPGWQGDNCEK-PVCKEGCHPTH-GRC-DRPGD--CDCRPGWR 236
D Y C+ P G L D+C P G H G C D G C C PG+
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198
Query: 237 GELCSQCQPYPGCKHGYCN-----------GSSWDCTCDTNWGGILCDQDLNYCGTHEPC 285
G C C+ G C+ G + C C + G C L+ C + +PC
Sbjct: 1199 GLRCEA--DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES-QPC 1255
Query: 286 QHGGTCE-NTAPD---QYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
QHGG C + P + C CA+ F G CERV C C G T RG C
Sbjct: 1256 QHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV-PCQQTPRGPRCA 1314
Query: 342 CD--------RGWGGXXXXXXXXXXASGPCLHGASCRDH--LDGFTCECADGWTGPACAE 391
C R + G A+ PCLHG SCR F C CA GWTGP C
Sbjct: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA 1374
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSC--ACLA---GWTGRDCETNVDDCTGQC 446
+ E + P AAC G C C + GW G DC +V D QC
Sbjct: 1375 PA------AAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
C L ++ C A + C D DC GG Y C F+
Sbjct: 1429 -EALQCWRLFNNSRCDPAC--SSPACLYDNFDCHA-----GGRERTCNPVYEKYCADHFA 1480
Query: 507 GTNCEDDRDHCAGSPCG-NGAAC 528
C+ C CG +G C
Sbjct: 1481 DGRCDQG---CNTEECGWDGLDC 1500
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 307 bits (754), Expect = 1e-82
Identities = 171/505 (33%), Positives = 224/505 (44%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCE-KPVCKEGCHPTHGRCDRP-------GDCDCRPGWRGELCSQCQP--YP 247
C PGW G+ C+ + C G G C C C G+RG CS P
Sbjct: 67 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 126
Query: 248 GCKHG-YCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C HG C+ + C+C + G C D++ C EPC+HGGTC NT P + C+C
Sbjct: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-PGSFRCQC 185
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
G++G CE PCAP PC + GTC +G + C C G+ G
Sbjct: 186 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT-YDCACLPGFEGQNCEVNVDDCPGHR 244
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
CL+G +C D ++ + C+C WTG C EDVDEC + C N C NT GG+
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP------NACHNGGTCFNTLGGH 298
Query: 423 SCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
SC C+ GWTG C N+DDC T C HGATC D V F+CAC G G C LD D C
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVS 357
Query: 482 RPCTNGGEC-VDLLNAYR-CICPVGFSGTNCEDDRDHCA--GSPCGNGAACYTAQSDYYC 537
PC C + +N C CP GF+G C+ D D C+ +PC + C Q + C
Sbjct: 358 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 417
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG C + C G C N TC+ G +
Sbjct: 418 QCGRGYTGPRCE--------------TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 463
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ GG C G++C C G +G+ C+L +D C S+PCR
Sbjct: 464 TYCEVDIDECQSSPCVN----GGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCR 517
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG +CV + C C G+ G C
Sbjct: 518 NGAKCVDQPDGYECRCAEGFEGTLC 542
Score = 293 bits (720), Expect = 2e-78
Identities = 190/570 (33%), Positives = 252/570 (44%), Gaps = 72/570 (12%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPVCKEGCHP 218
C P Y T C + CR + + G C DK+ C G G NCE + +P
Sbjct: 570 CAPGYTGTRCESQVDECRSQPCRHGG-KCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNP 628
Query: 219 -THGRCDRPG----DCDCRPGWRGELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNW 267
T G C R G DC C+PG+ G LC+ +C P + G C + + C C
Sbjct: 629 CTFGVC-RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
Query: 268 GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER--VDNPCAPQPC- 324
LC + C HEPC HG C + AP + C C G+SG C + + C QPC
Sbjct: 688 LPPLCLPPSHPCA-HEPCSHG-ICYD-APGGFRCVCEPGWSGPRCSQSLARDACESQPCR 744
Query: 325 AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF-TCECADG 383
A GTCS G GF CTC G G + PC HG C C C G
Sbjct: 745 AGGTCSSDGM--GFHCTCPPGVQGRQCELLSPCTPN-PCEHGGRCESAPGQLPVCSCPQG 801
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT 443
W GP C +DVDEC+G + PC C N AG +SC C G+TG C+ +++DC
Sbjct: 802 WQGPRCQQDVDECAGPA-------PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
Query: 444 -GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
CL+G +C D V F C+C G+AG C+ DVD+C PC G C D + ++ C CP
Sbjct: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCP 913
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR----------- 551
G+ G +CE D C+ S C NG C + + C C PG+TG +C
Sbjct: 914 PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLH 973
Query: 552 -----AARDRKTCSVLVEES--------ERCAEGMCANGGTCVREEG------SWRXXXX 592
AA C+ L + + C+ C NGG CV+ W
Sbjct: 974 GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLC 1033
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
++ QAGG C+ C C EGRTG+ CE +D C
Sbjct: 1034 DIRSLPCREAAAQIGVRLEQLC--QAGGQCVDE--DSSHYCVCPEGRTGSHCEQEVDPCL 1089
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ PC++GG C G G +MCEC+ G+ G+ C
Sbjct: 1090 AQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
Score = 291 bits (713), Expect = 1e-77
Identities = 182/546 (33%), Positives = 245/546 (44%), Gaps = 55/546 (10%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSC--TPDGDK-HCLPGWQGDNCEKPV--CKEGC 216
C P Y +C + CR + +C TP + C G+ G CE P C
Sbjct: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP 205
Query: 217 HPTHGRCDRPGD----CDCRPGWRGELCS----QCQPYPGCKHGYC-NG-SSWDCTCDTN 266
G C + GD C C PG+ G+ C C + G C +G ++++C C
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE 265
Query: 267 WGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C +D++ C C +GGTC NT + C C G++G C + + CA C
Sbjct: 266 WTGQFCTEDVDECQLQPNACHNGGTCFNTLGG-HSCVCVNGWTGESCSQNIDDCATAVCF 324
Query: 326 HG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH-LDGFT-CECAD 382
HG TC F C C G G S PC A C + ++G C C
Sbjct: 325 HGATCH--DRVASFYCACPMGKTGLLCHLDDAC-VSNPCHEDAICDTNPVNGRAICTCPP 381
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G+TG AC +DVDECS GA PC + C NT G + C C G+TG CET+V++C
Sbjct: 382 GFTGGACDQDVDECS-----IGA-NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 435
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+G C + ATC+D + F C C AG+ G C +D+D+C PC NGG C D +N + C C
Sbjct: 436 LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC 495
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P GFSG+ C+ D D CA +PC NGA C Y C CA G+ G C R+ CS
Sbjct: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD----RNVDDCSP 551
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
RC +G+ + C R + GG
Sbjct: 552 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP---------------CRHGGK 596
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGET 681
CL L + C C G TG CE+++D C S+PC G C G + C C G+TG
Sbjct: 597 CLD--LVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPL 653
Query: 682 CAVRVS 687
C V ++
Sbjct: 654 CNVEIN 659
Score = 290 bits (712), Expect = 1e-77
Identities = 170/502 (33%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT---HGR-C-DRPGD--CDCRPGWRGELC---SQCQPYP 247
C+ GW G++C + + + C HG C DR C C G G LC C P
Sbjct: 302 CVNGWTGESCSQNI--DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 359
Query: 248 GCKHGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
+ C+ + + CTC + G CDQD++ C PC+H G C NT + C+
Sbjct: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ-GSFLCQ 418
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G++G CE N C PC + L + FTC C G+ G S P
Sbjct: 419 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTCICMAGFTGTYCEVDIDECQSSP 477
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C++G C+D ++GF+C C G++G C DVDEC+ PC N A C + GY
Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST--------PCRNGAKCVDQPDGY 529
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G+ G C+ NVDDC+ H C+D + F CACA GY G C VD+C +
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC +GG+C+DL++ Y C CP G +G NCE + D CA +PC G C + Y C C PG
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPG 648
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C+V + E CA C GG+CV E +R
Sbjct: 649 FTG-----------PLCNVEINE---CASSPCGEGGSCVDGENGFRCLCPPGSL-----P 689
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL--DLCGSSPCRNGG 660
+ G C + P G+ C C G +G C SL D C S PCR GG
Sbjct: 690 PLCLPPSHPCAHEPCSHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
C + C C G G C
Sbjct: 748 TCSSDGMGFHCTCPPGVQGRQC 769
Score = 287 bits (704), Expect = 1e-76
Identities = 165/509 (32%), Positives = 226/509 (44%), Gaps = 58/509 (11%)
Query: 195 DKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS---- 241
D CLPG++G NCE V + C P H RC G +C C P W G+ C+
Sbjct: 221 DCACLPGFEGQNCEVNV--DDC-PGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 276
Query: 242 QCQPYPGCKH--GYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+CQ P H G C + C C W G C Q+++ C T C HG TC +
Sbjct: 277 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDRVA- 334
Query: 298 QYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
++C C G +G+ C +D+ C PC C CTC G+ G
Sbjct: 335 SFYCACPMGKTGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD 393
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+ G PC H C + F C+C G+TGP C DV+EC GPC N A
Sbjct: 394 ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS--------GPCRNQAT 445
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C + G ++C C+AG+TG CE ++D+C + C++G C D V+ F C C +G++G TC
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
LDVD+CA PC NG +CVD + Y C C GF GT C+ + D C+ PC +G C +
Sbjct: 506 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIA 564
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+ C CAPG+TG C + + C C +GG C+ +
Sbjct: 565 SFSCACAPGYTGTRCESQV--------------DECRSQPCRHGGKCLDLVDKYLCRCPS 610
Query: 594 XXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGS 653
+ G C + C C+ G TG LC + ++ C S
Sbjct: 611 GTTGVNCEVNIDDCASNPCTF-----GVCRDGI--NRYDCVCQPGFTGPLCNVEINECAS 663
Query: 654 SPCRNGGRCVGGSGWWMCECVAGWTGETC 682
SPC GG CV G + C C G C
Sbjct: 664 SPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
Score = 271 bits (665), Expect = 7e-72
Identities = 168/519 (32%), Positives = 226/519 (43%), Gaps = 53/519 (10%)
Query: 189 SCTPDGDK--HCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPGD--CDCRPGWRGELC 240
S PDG C PG+QG +C V C+ G HG C + PG C C G+ G LC
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Query: 241 SQ----CQPYPGCKHGYCNGS---SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCEN 293
C P P G C S ++DC C + G C+ +++ C H C +GGTC +
Sbjct: 195 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVD 253
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ Y C+C ++G C + C QP A H + T G +C C GW G
Sbjct: 254 GV-NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
A+ C HGA+C D + F C C G TG C D D C PC
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSN--------PCHED 363
Query: 413 AACN-NTAGGYS-CACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
A C+ N G + C C G+TG C+ +VD+C+ C H C++ F C C GY
Sbjct: 364 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 423
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C DV++C PC N C+D + + CIC GF+GT CE D D C SPC NG
Sbjct: 424 TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 483
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + C C G++G TC + V+E CA C NG CV + +
Sbjct: 484 CKDRVNGFSCTCPSGFSGS-----------TCQLDVDE---CASTPCRNGAKCVDQPDGY 529
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
D G C+ ++C C G TG CE
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHH-----GRCVDGIA--SFSCACAPGYTGTRCESQ 582
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PCR+GG+C+ ++C C +G TG C V +
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI 621
Score = 265 bits (650), Expect = 5e-70
Identities = 200/684 (29%), Positives = 262/684 (38%), Gaps = 91/684 (13%)
Query: 164 LCQPNYYNTTCTTFCRP-RDDKFGHYSC--TPDGDKH-CLPGWQGDNCEKPVCKEGCHP- 218
LC P C P + H C P G + C PGW G C + + ++ C
Sbjct: 682 LCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ 741
Query: 219 ---THGRCDRPG---DCDCRPGWRG---ELCSQCQPYPGCKHG-YCNGSSWD---CTCDT 265
G C G C C PG +G EL S C P P C+HG C + C+C
Sbjct: 742 PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP-CEHGGRCESAPGQLPVCSCPQ 800
Query: 266 NWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C QD++ C PC G C N A + C C G++G C++ N C P PC
Sbjct: 801 GWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSCTCHGGYTGPSCDQDINDCDPNPCL 859
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT 385
+G G F+C+C G+ G S PC G +C DH+ FTC C G+
Sbjct: 860 NGGSCQDGVG-SFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYG 917
Query: 386 GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ 445
G C +D+ +CS S C N C + +SC C G+TG C+ D C +
Sbjct: 918 GFHCEQDLPDCSPSS--------CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 446 -CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
CLHG C F C C + G C VD C+ +PC NGG CV AY C+CP G
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPG 1027
Query: 505 FSGTNCEDDRDHCAGSP----------CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+SG C+ C + C G C S +YC C G TG +C Q
Sbjct: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ---- 1083
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
E + C C +GGTC G + +
Sbjct: 1084 ----------EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC-- 1131
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNGGRCVGGSG 667
Q GG+C+ L + C C G G LCE++ D CG P C + G CV G
Sbjct: 1132 --QHGGSCID--LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVG 1187
Query: 668 WWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAARR 727
+ C C G+TG C ++ RCLC A + R
Sbjct: 1188 GFRCTCPPGYTGLRCEADIN---ECRSGACHAAHTRDCLQDPGGGFRCLCHA--GFSGPR 1242
Query: 728 CLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDG-PGACGVANGTWWWGCNACWCSGG 786
C ++ E+ Q HG RP P G G C A +WG C
Sbjct: 1243 CQTVLSPCES--------QPCQHGGQCRPSPGPGGGLTFTCHCAQP--FWGPR---CERV 1289
Query: 787 VPTCTRLWC--GLPDCLAPNAQPC 808
+C L C G+P P C
Sbjct: 1290 ARSCRELQCPVGVPCQQTPRGPRC 1313
Score = 261 bits (640), Expect = 8e-69
Identities = 151/500 (30%), Positives = 204/500 (40%), Gaps = 47/500 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
C G+ G CE V C G C DR G C C G+ G C +CQ P
Sbjct: 419 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 478
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C + + CTC + + G C D++ C + PC++G C + PD Y CRCAEG
Sbjct: 479 VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAS-TPCRNGAKCVDQ-PDGYECRCAEG 536
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
F G C+R + C+P PC HG C F+C C G+ G S PC HG
Sbjct: 537 FEGTLCDRNVDDCSPDPCHHGRC--VDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG 594
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C D +D + C C G TG C ++D+C+ T G C + Y C C
Sbjct: 595 GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV---------CRDGINRYDCVC 645
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C +++C C G +C+D + F C C G C CA PC+
Sbjct: 646 QPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS 705
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDD--RDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+G C D +RC+C G+SG C RD C PC G C + ++C C PG
Sbjct: 706 HG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+ C E C C +GG C G
Sbjct: 765 QGRQC---------------ELLSPCTPNPCEHGGRCESAPGQ----LPVCSCPQGWQGP 805
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G + + L ++C C G TG C+ ++ C +PC NGG C
Sbjct: 806 RCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 865
Query: 664 GGSGWWMCECVAGWTGETCA 683
G G + C C+ G+ G CA
Sbjct: 866 DGVGSFSCSCLPGFAGPRCA 885
Score = 250 bits (612), Expect = 2e-65
Identities = 138/435 (31%), Positives = 191/435 (43%), Gaps = 38/435 (8%)
Query: 261 CTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERVD 316
C C W G C +D + G PC G C+++ ++ CRC GF G DC D
Sbjct: 65 CLCPPGWVGERCQLEDPCHSG---PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD 121
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDG 375
PC PCAHG G F C+C G+ G G PC HG +C +
Sbjct: 122 -PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 180
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRD 434
F C+C G+TGP C C A PC N C + Y CACL G+ G++
Sbjct: 181 FRCQCPAGYTGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
Query: 435 CETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECV 491
CE NVDDC G +CL+G TC+D V+ ++C C + G+ C+ DVD+C P C NGG C
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF 292
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
+ L + C+C G++G +C + D CA + C +GA C+ + +YC C G TG
Sbjct: 293 NTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTG------ 346
Query: 552 AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXX 611
+L + C C C + R
Sbjct: 347 ---------LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 397
Query: 612 XXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMC 671
+ G C+ + + C C G TG CE ++ C S PCRN C+ G + C
Sbjct: 398 GANPCEHLGRCVNT--QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
Query: 672 ECVAGWTGETCAVRV 686
C+AG+TG C V +
Sbjct: 456 ICMAGFTGTYCEVDI 470
Score = 244 bits (597), Expect = 1e-63
Identities = 157/504 (31%), Positives = 208/504 (41%), Gaps = 51/504 (10%)
Query: 204 GDNCEKPVCKEGCHPTHG-RC----DRPGDCDCRPGWRGELCS---QCQPYPGCKHGYCN 255
G P C +G +G RC R C C PGW GE C C P G C
Sbjct: 35 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ 94
Query: 256 GS------SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S + C C + G C + C PC HG C ++ C C G+ G
Sbjct: 95 SSVVAGTARFSCRCPRGFRGPDCSLP-DPC-LSSPCAHGARCSVGPDGRFLCSCPPGYQG 152
Query: 310 VDCER-VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
C VD +PC HG L T F C C G+ G A PC +G +
Sbjct: 153 RSCRSDVDECRVGEPCRHGGTCL-NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 211
Query: 369 CRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
CR D + C C G+ G C +VD+C G C+N C + Y+C C
Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR--------CLNGGTCVDGVNTYNCQCP 263
Query: 428 AGWTGRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
WTG+ C +VD+C Q C +G TC + + C C G+ G +CS ++DDCA C
Sbjct: 264 PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVC 323
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPG 542
+G C D + ++ C CP+G +G C D D C +PC A C T C C PG
Sbjct: 324 FHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPG 382
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C Q D CS+ C + G CV +GS+ ++
Sbjct: 383 FTGGACDQ----DVDECSI--------GANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET 430
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC 662
QA TCL + C C G TG CE+ +D C SSPC NGG C
Sbjct: 431 --DVNECLSGPCRNQA--TCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 484
Query: 663 VGGSGWWMCECVAGWTGETCAVRV 686
+ C C +G++G TC + V
Sbjct: 485 KDRVNGFSCTCPSGFSGSTCQLDV 508
Score = 241 bits (589), Expect = 1e-62
Identities = 139/420 (33%), Positives = 185/420 (44%), Gaps = 40/420 (9%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCS---LAGT 334
C PC +GG C + C C G+ G C+ +++PC PCA G C +AGT
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 101
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDV 393
R F+C C RG+ G +S PC HGA C DG F C C G+ G +C DV
Sbjct: 102 AR-FSCRCPRGFRGPDCSLPDPCLSS-PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 159
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATC 452
DEC PC + C NT G + C C AG+TG CE C C +G TC
Sbjct: 160 DECRVGE-------PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212
Query: 453 IDLVD-DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
D + CAC G+ G+ C ++VDDC C NGG CVD +N Y C CP ++G C
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 272
Query: 512 DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
+D D C P C NG C+ + C C GWTG++C+Q + C
Sbjct: 273 EDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI--------------DDC 318
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
A +C +G TC R C + +
Sbjct: 319 ATAVCFHGATC-----HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG 373
Query: 630 GWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C C G TG C+ +D C G++PC + GRCV G ++C+C G+TG C V+
Sbjct: 374 RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 433
Score = 219 bits (536), Expect = 3e-56
Identities = 156/536 (29%), Positives = 213/536 (39%), Gaps = 73/536 (13%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRCD---RPGDCDCRPGWRGELCSQ----CQPYPG 248
C PG+ G +CE+ P C G C C CRPG+ G C C P
Sbjct: 912 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
Query: 249 CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C+ + + CTC ++ G C +++C + +PCQ+GG C T +C C G
Sbjct: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWC-SRQPCQNGGRCVQTGA---YCLCPPG 1027
Query: 307 FSGVDCERVDNPCAPQPCAHGT-----CSLAGTT----RGFTCTCDRGWGGXXXXXXXXX 357
+SG C+ PC G C G C C G G
Sbjct: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP 1087
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
+ PC HG +CR ++ G+ CEC G+ G C +DVDEC+ + PC + +C +
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQ--------PCQHGGSCID 1139
Query: 418 TAGGYSCACLAGWTGRDCETNVDDC-------TG-QCLHGATCIDLVDDFHCACAAGYAG 469
Y C+C G G CE N DDC +G +CLH TC+DLV F C C GY G
Sbjct: 1140 LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1199
Query: 470 RTCSLDVDDCAPRPC--TNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
C D+++C C + +C+ D +RC+C GFSG C+ C PC +G
Sbjct: 1200 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGG 1259
Query: 527 ACYTAQS-----DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C + + CHCA + G C +R AR C E C G C
Sbjct: 1260 QCRPSPGPGGGLTFTCHCAQPFWGPRC-ERVARS-------------CRELQCPVGVPCQ 1305
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA----GGTCLPSALPPGWACGCRE 637
+ R S A GG+C P+ L P + C C +
Sbjct: 1306 QTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365
Query: 638 GRTGALCE--LSLDLCGSSPCRNGGRCVGGSGWWMC--ECVA---GWTGETCAVRV 686
G TG CE + P C G C EC + GW G C++ V
Sbjct: 1366 GWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSV 1421
Score = 194 bits (473), Expect = 1e-48
Identities = 143/458 (31%), Positives = 179/458 (39%), Gaps = 61/458 (13%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHY--SCTPDGDKHCLPGWQGDNCEKPV--CKEGC 216
LC+P Y C C R G + P CL + G C+ V C
Sbjct: 949 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 1008
Query: 217 HPTHGRCDRPGD-CDCRPGWRGELCS----QCQPYPG---------CKHG-YC--NGSSW 259
GRC + G C C PGW G LC C+ C+ G C SS
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
Query: 260 DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C G C+Q+++ C +PCQHGGTC Y C C G++G +CE + C
Sbjct: 1069 YCVCPEGRTGSHCEQEVDPC-LAQPCQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDEC 1126
Query: 320 APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLHGASCRDH 372
A QPC HG + R + C+C G G GP CLH +C D
Sbjct: 1127 ASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ GF C C G+TG C D++EC RS GA + GG+ C C AG++G
Sbjct: 1186 VGGFRCTCPPGYTGLRCEADINEC--RS---GACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDD-----FHCACAAGYAGRTCSLDVDDCAPRPCTN 486
C+T + C Q C HG C F C CA + G C C C
Sbjct: 1241 PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPV 1300
Query: 487 GGECVDLLNAYRCICPVGFSGTNCED--------DRDHCAGSPCGNGAACYTA--QSDYY 536
G C RC CP G SG +C CA +PC +G +C A +
Sbjct: 1301 GVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFR 1360
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C CA GWTG C AA V E RC C
Sbjct: 1361 CACAQGWTGPRCEAPAAAPE------VSEEPRCPRAAC 1392
Score = 111 bits (268), Expect = 9e-24
Identities = 113/383 (29%), Positives = 138/383 (36%), Gaps = 58/383 (15%)
Query: 183 DKFGHYSCT-PDGDKHCLPGWQGDNCEK-PVCKEGCHPTH-GRC-DRPGD--CDCRPGWR 236
D Y C+ P G L D+C P G H G C D G C C PG+
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198
Query: 237 GELCSQCQPYPGCKHGYCN-----------GSSWDCTCDTNWGGILCDQDLNYCGTHEPC 285
G C C+ G C+ G + C C + G C L+ C + +PC
Sbjct: 1199 GLRCEA--DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES-QPC 1255
Query: 286 QHGGTCE-NTAPD---QYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
QHGG C + P + C CA+ F G CERV C C G T RG C
Sbjct: 1256 QHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV-PCQQTPRGPRCA 1314
Query: 342 CD--------RGWGGXXXXXXXXXXASGPCLHGASCRDH--LDGFTCECADGWTGPACAE 391
C R + G A+ PCLHG SCR F C CA GWTGP C
Sbjct: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA 1374
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSC--ACLA---GWTGRDCETNVDDCTGQC 446
+ E + P AAC G C C + GW G DC +V D QC
Sbjct: 1375 PA------AAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
C L ++ C A + C D DC GG Y C F+
Sbjct: 1429 -EALQCWRLFNNSRCDPAC--SSPACLYDNFDCHA-----GGRERTCNPVYEKYCADHFA 1480
Query: 507 GTNCEDDRDHCAGSPCG-NGAAC 528
C+ C CG +G C
Sbjct: 1481 DGRCDQG---CNTEECGWDGLDC 1500
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 307 bits (754), Expect = 1e-82
Identities = 171/505 (33%), Positives = 224/505 (44%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCE-KPVCKEGCHPTHGRCDRP-------GDCDCRPGWRGELCSQCQP--YP 247
C PGW G+ C+ + C G G C C C G+RG CS P
Sbjct: 27 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 86
Query: 248 GCKHG-YCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C HG C+ + C+C + G C D++ C EPC+HGGTC NT P + C+C
Sbjct: 87 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-PGSFRCQC 145
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
G++G CE PCAP PC + GTC +G + C C G+ G
Sbjct: 146 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT-YDCACLPGFEGQNCEVNVDDCPGHR 204
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
CL+G +C D ++ + C+C WTG C EDVDEC + C N C NT GG+
Sbjct: 205 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP------NACHNGGTCFNTLGGH 258
Query: 423 SCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
SC C+ GWTG C N+DDC T C HGATC D V F+CAC G G C LD D C
Sbjct: 259 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVS 317
Query: 482 RPCTNGGEC-VDLLNAYR-CICPVGFSGTNCEDDRDHCA--GSPCGNGAACYTAQSDYYC 537
PC C + +N C CP GF+G C+ D D C+ +PC + C Q + C
Sbjct: 318 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 377
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG C + C G C N TC+ G +
Sbjct: 378 QCGRGYTGPRCE--------------TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 423
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ GG C G++C C G +G+ C+L +D C S+PCR
Sbjct: 424 TYCEVDIDECQSSPCVN----GGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCR 477
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG +CV + C C G+ G C
Sbjct: 478 NGAKCVDQPDGYECRCAEGFEGTLC 502
Score = 293 bits (720), Expect = 2e-78
Identities = 190/570 (33%), Positives = 252/570 (44%), Gaps = 72/570 (12%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPVCKEGCHP 218
C P Y T C + CR + + G C DK+ C G G NCE + +P
Sbjct: 530 CAPGYTGTRCESQVDECRSQPCRHGG-KCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNP 588
Query: 219 -THGRCDRPG----DCDCRPGWRGELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNW 267
T G C R G DC C+PG+ G LC+ +C P + G C + + C C
Sbjct: 589 CTFGVC-RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 647
Query: 268 GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER--VDNPCAPQPC- 324
LC + C HEPC HG C + AP + C C G+SG C + + C QPC
Sbjct: 648 LPPLCLPPSHPCA-HEPCSHG-ICYD-APGGFRCVCEPGWSGPRCSQSLARDACESQPCR 704
Query: 325 AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF-TCECADG 383
A GTCS G GF CTC G G + PC HG C C C G
Sbjct: 705 AGGTCSSDGM--GFHCTCPPGVQGRQCELLSPCTPN-PCEHGGRCESAPGQLPVCSCPQG 761
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT 443
W GP C +DVDEC+G + PC C N AG +SC C G+TG C+ +++DC
Sbjct: 762 WQGPRCQQDVDECAGPA-------PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 814
Query: 444 -GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
CL+G +C D V F C+C G+AG C+ DVD+C PC G C D + ++ C CP
Sbjct: 815 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCP 873
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR----------- 551
G+ G +CE D C+ S C NG C + + C C PG+TG +C
Sbjct: 874 PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLH 933
Query: 552 -----AARDRKTCSVLVEES--------ERCAEGMCANGGTCVREEG------SWRXXXX 592
AA C+ L + + C+ C NGG CV+ W
Sbjct: 934 GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLC 993
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
++ QAGG C+ C C EGRTG+ CE +D C
Sbjct: 994 DIRSLPCREAAAQIGVRLEQLC--QAGGQCVDE--DSSHYCVCPEGRTGSHCEQEVDPCL 1049
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ PC++GG C G G +MCEC+ G+ G+ C
Sbjct: 1050 AQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1079
Score = 291 bits (713), Expect = 1e-77
Identities = 182/546 (33%), Positives = 245/546 (44%), Gaps = 55/546 (10%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSC--TPDGDK-HCLPGWQGDNCEKPV--CKEGC 216
C P Y +C + CR + +C TP + C G+ G CE P C
Sbjct: 106 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP 165
Query: 217 HPTHGRCDRPGD----CDCRPGWRGELCS----QCQPYPGCKHGYC-NG-SSWDCTCDTN 266
G C + GD C C PG+ G+ C C + G C +G ++++C C
Sbjct: 166 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE 225
Query: 267 WGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C +D++ C C +GGTC NT + C C G++G C + + CA C
Sbjct: 226 WTGQFCTEDVDECQLQPNACHNGGTCFNTLGG-HSCVCVNGWTGESCSQNIDDCATAVCF 284
Query: 326 HG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH-LDGFT-CECAD 382
HG TC F C C G G S PC A C + ++G C C
Sbjct: 285 HGATCH--DRVASFYCACPMGKTGLLCHLDDAC-VSNPCHEDAICDTNPVNGRAICTCPP 341
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G+TG AC +DVDECS GA PC + C NT G + C C G+TG CET+V++C
Sbjct: 342 GFTGGACDQDVDECS-----IGA-NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 395
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+G C + ATC+D + F C C AG+ G C +D+D+C PC NGG C D +N + C C
Sbjct: 396 LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC 455
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P GFSG+ C+ D D CA +PC NGA C Y C CA G+ G C R+ CS
Sbjct: 456 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD----RNVDDCSP 511
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
RC +G+ + C R + GG
Sbjct: 512 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP---------------CRHGGK 556
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGET 681
CL L + C C G TG CE+++D C S+PC G C G + C C G+TG
Sbjct: 557 CLD--LVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPL 613
Query: 682 CAVRVS 687
C V ++
Sbjct: 614 CNVEIN 619
Score = 290 bits (712), Expect = 1e-77
Identities = 170/502 (33%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT---HGR-C-DRPGD--CDCRPGWRGELC---SQCQPYP 247
C+ GW G++C + + + C HG C DR C C G G LC C P
Sbjct: 262 CVNGWTGESCSQNI--DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 319
Query: 248 GCKHGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
+ C+ + + CTC + G CDQD++ C PC+H G C NT + C+
Sbjct: 320 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ-GSFLCQ 378
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G++G CE N C PC + L + FTC C G+ G S P
Sbjct: 379 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTCICMAGFTGTYCEVDIDECQSSP 437
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C++G C+D ++GF+C C G++G C DVDEC+ PC N A C + GY
Sbjct: 438 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST--------PCRNGAKCVDQPDGY 489
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G+ G C+ NVDDC+ H C+D + F CACA GY G C VD+C +
Sbjct: 490 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 549
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC +GG+C+DL++ Y C CP G +G NCE + D CA +PC G C + Y C C PG
Sbjct: 550 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPG 608
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C+V + E CA C GG+CV E +R
Sbjct: 609 FTG-----------PLCNVEINE---CASSPCGEGGSCVDGENGFRCLCPPGSL-----P 649
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL--DLCGSSPCRNGG 660
+ G C + P G+ C C G +G C SL D C S PCR GG
Sbjct: 650 PLCLPPSHPCAHEPCSHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 707
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
C + C C G G C
Sbjct: 708 TCSSDGMGFHCTCPPGVQGRQC 729
Score = 287 bits (704), Expect = 1e-76
Identities = 165/509 (32%), Positives = 226/509 (44%), Gaps = 58/509 (11%)
Query: 195 DKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS---- 241
D CLPG++G NCE V + C P H RC G +C C P W G+ C+
Sbjct: 181 DCACLPGFEGQNCEVNV--DDC-PGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 236
Query: 242 QCQPYPGCKH--GYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+CQ P H G C + C C W G C Q+++ C T C HG TC +
Sbjct: 237 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDRVA- 294
Query: 298 QYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
++C C G +G+ C +D+ C PC C CTC G+ G
Sbjct: 295 SFYCACPMGKTGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD 353
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+ G PC H C + F C+C G+TGP C DV+EC GPC N A
Sbjct: 354 ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS--------GPCRNQAT 405
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C + G ++C C+AG+TG CE ++D+C + C++G C D V+ F C C +G++G TC
Sbjct: 406 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 465
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
LDVD+CA PC NG +CVD + Y C C GF GT C+ + D C+ PC +G C +
Sbjct: 466 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIA 524
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+ C CAPG+TG C + + C C +GG C+ +
Sbjct: 525 SFSCACAPGYTGTRCESQV--------------DECRSQPCRHGGKCLDLVDKYLCRCPS 570
Query: 594 XXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGS 653
+ G C + C C+ G TG LC + ++ C S
Sbjct: 571 GTTGVNCEVNIDDCASNPCTF-----GVCRDGI--NRYDCVCQPGFTGPLCNVEINECAS 623
Query: 654 SPCRNGGRCVGGSGWWMCECVAGWTGETC 682
SPC GG CV G + C C G C
Sbjct: 624 SPCGEGGSCVDGENGFRCLCPPGSLPPLC 652
Score = 271 bits (665), Expect = 7e-72
Identities = 168/519 (32%), Positives = 226/519 (43%), Gaps = 53/519 (10%)
Query: 189 SCTPDGDK--HCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPGD--CDCRPGWRGELC 240
S PDG C PG+QG +C V C+ G HG C + PG C C G+ G LC
Sbjct: 95 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 154
Query: 241 SQ----CQPYPGCKHGYCNGS---SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCEN 293
C P P G C S ++DC C + G C+ +++ C H C +GGTC +
Sbjct: 155 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVD 213
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ Y C+C ++G C + C QP A H + T G +C C GW G
Sbjct: 214 GV-NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 272
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
A+ C HGA+C D + F C C G TG C D D C PC
Sbjct: 273 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSN--------PCHED 323
Query: 413 AACN-NTAGGYS-CACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
A C+ N G + C C G+TG C+ +VD+C+ C H C++ F C C GY
Sbjct: 324 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 383
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C DV++C PC N C+D + + CIC GF+GT CE D D C SPC NG
Sbjct: 384 TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 443
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + C C G++G TC + V+E CA C NG CV + +
Sbjct: 444 CKDRVNGFSCTCPSGFSGS-----------TCQLDVDE---CASTPCRNGAKCVDQPDGY 489
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
D G C+ ++C C G TG CE
Sbjct: 490 ECRCAEGFEGTLCDRNVDDCSPDPCHH-----GRCVDGIA--SFSCACAPGYTGTRCESQ 542
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PCR+GG+C+ ++C C +G TG C V +
Sbjct: 543 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI 581
Score = 265 bits (650), Expect = 5e-70
Identities = 200/684 (29%), Positives = 262/684 (38%), Gaps = 91/684 (13%)
Query: 164 LCQPNYYNTTCTTFCRP-RDDKFGHYSC--TPDGDKH-CLPGWQGDNCEKPVCKEGCHP- 218
LC P C P + H C P G + C PGW G C + + ++ C
Sbjct: 642 LCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ 701
Query: 219 ---THGRCDRPG---DCDCRPGWRG---ELCSQCQPYPGCKHG-YCNGSSWD---CTCDT 265
G C G C C PG +G EL S C P P C+HG C + C+C
Sbjct: 702 PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP-CEHGGRCESAPGQLPVCSCPQ 760
Query: 266 NWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C QD++ C PC G C N A + C C G++G C++ N C P PC
Sbjct: 761 GWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSCTCHGGYTGPSCDQDINDCDPNPCL 819
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT 385
+G G F+C+C G+ G S PC G +C DH+ FTC C G+
Sbjct: 820 NGGSCQDGVG-SFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYG 877
Query: 386 GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ 445
G C +D+ +CS S C N C + +SC C G+TG C+ D C +
Sbjct: 878 GFHCEQDLPDCSPSS--------CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 929
Query: 446 -CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
CLHG C F C C + G C VD C+ +PC NGG CV AY C+CP G
Sbjct: 930 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPG 987
Query: 505 FSGTNCEDDRDHCAGSP----------CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+SG C+ C + C G C S +YC C G TG +C Q
Sbjct: 988 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ---- 1043
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
E + C C +GGTC G + +
Sbjct: 1044 ----------EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC-- 1091
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNGGRCVGGSG 667
Q GG+C+ L + C C G G LCE++ D CG P C + G CV G
Sbjct: 1092 --QHGGSCID--LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVG 1147
Query: 668 WWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAARR 727
+ C C G+TG C ++ RCLC A + R
Sbjct: 1148 GFRCTCPPGYTGLRCEADIN---ECRSGACHAAHTRDCLQDPGGGFRCLCHA--GFSGPR 1202
Query: 728 CLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDG-PGACGVANGTWWWGCNACWCSGG 786
C ++ E+ Q HG RP P G G C A +WG C
Sbjct: 1203 CQTVLSPCES--------QPCQHGGQCRPSPGPGGGLTFTCHCAQP--FWGPR---CERV 1249
Query: 787 VPTCTRLWC--GLPDCLAPNAQPC 808
+C L C G+P P C
Sbjct: 1250 ARSCRELQCPVGVPCQQTPRGPRC 1273
Score = 261 bits (640), Expect = 8e-69
Identities = 151/500 (30%), Positives = 204/500 (40%), Gaps = 47/500 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
C G+ G CE V C G C DR G C C G+ G C +CQ P
Sbjct: 379 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPC 438
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C + + CTC + + G C D++ C + PC++G C + PD Y CRCAEG
Sbjct: 439 VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAS-TPCRNGAKCVDQ-PDGYECRCAEG 496
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
F G C+R + C+P PC HG C F+C C G+ G S PC HG
Sbjct: 497 FEGTLCDRNVDDCSPDPCHHGRC--VDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG 554
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C D +D + C C G TG C ++D+C+ T G C + Y C C
Sbjct: 555 GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV---------CRDGINRYDCVC 605
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C +++C C G +C+D + F C C G C CA PC+
Sbjct: 606 QPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS 665
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDD--RDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+G C D +RC+C G+SG C RD C PC G C + ++C C PG
Sbjct: 666 HG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 724
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+ C E C C +GG C G
Sbjct: 725 QGRQC---------------ELLSPCTPNPCEHGGRCESAPGQ----LPVCSCPQGWQGP 765
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G + + L ++C C G TG C+ ++ C +PC NGG C
Sbjct: 766 RCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 825
Query: 664 GGSGWWMCECVAGWTGETCA 683
G G + C C+ G+ G CA
Sbjct: 826 DGVGSFSCSCLPGFAGPRCA 845
Score = 250 bits (612), Expect = 2e-65
Identities = 138/435 (31%), Positives = 191/435 (43%), Gaps = 38/435 (8%)
Query: 261 CTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERVD 316
C C W G C +D + G PC G C+++ ++ CRC GF G DC D
Sbjct: 25 CLCPPGWVGERCQLEDPCHSG---PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD 81
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDG 375
PC PCAHG G F C+C G+ G G PC HG +C +
Sbjct: 82 -PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 140
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRD 434
F C+C G+TGP C C A PC N C + Y CACL G+ G++
Sbjct: 141 FRCQCPAGYTGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCACLPGFEGQN 192
Query: 435 CETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECV 491
CE NVDDC G +CL+G TC+D V+ ++C C + G+ C+ DVD+C P C NGG C
Sbjct: 193 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF 252
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
+ L + C+C G++G +C + D CA + C +GA C+ + +YC C G TG
Sbjct: 253 NTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTG------ 306
Query: 552 AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXX 611
+L + C C C + R
Sbjct: 307 ---------LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 357
Query: 612 XXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMC 671
+ G C+ + + C C G TG CE ++ C S PCRN C+ G + C
Sbjct: 358 GANPCEHLGRCVNT--QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 415
Query: 672 ECVAGWTGETCAVRV 686
C+AG+TG C V +
Sbjct: 416 ICMAGFTGTYCEVDI 430
Score = 243 bits (594), Expect = 3e-63
Identities = 156/498 (31%), Positives = 207/498 (41%), Gaps = 51/498 (10%)
Query: 210 PVCKEGCHPTHG-RC----DRPGDCDCRPGWRGELCS---QCQPYPGCKHGYCNGS---- 257
P C +G +G RC R C C PGW GE C C P G C S
Sbjct: 1 PPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAG 60
Query: 258 --SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER- 314
+ C C + G C + C PC HG C ++ C C G+ G C
Sbjct: 61 TARFSCRCPRGFRGPDCSLP-DPC-LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSD 118
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
VD +PC HG L T F C C G+ G A PC +G +CR D
Sbjct: 119 VDECRVGEPCRHGGTCL-NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 177
Query: 375 -GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
+ C C G+ G C +VD+C G C+N C + Y+C C WTG+
Sbjct: 178 LTYDCACLPGFEGQNCEVNVDDCPGHR--------CLNGGTCVDGVNTYNCQCPPEWTGQ 229
Query: 434 DCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
C +VD+C Q C +G TC + + C C G+ G +CS ++DDCA C +G C
Sbjct: 230 FCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATC 289
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNC 548
D + ++ C CP+G +G C D D C +PC A C T C C PG+TG C
Sbjct: 290 HDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC 348
Query: 549 TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
Q D CS+ C + G CV +GS+ ++
Sbjct: 349 DQ----DVDECSI--------GANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET--DVNE 394
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW 668
QA TCL + C C G TG CE+ +D C SSPC NGG C
Sbjct: 395 CLSGPCRNQA--TCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG 450
Query: 669 WMCECVAGWTGETCAVRV 686
+ C C +G++G TC + V
Sbjct: 451 FSCTCPSGFSGSTCQLDV 468
Score = 241 bits (589), Expect = 1e-62
Identities = 139/420 (33%), Positives = 185/420 (44%), Gaps = 40/420 (9%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCS---LAGT 334
C PC +GG C + C C G+ G C+ +++PC PCA G C +AGT
Sbjct: 3 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 61
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDV 393
R F+C C RG+ G +S PC HGA C DG F C C G+ G +C DV
Sbjct: 62 AR-FSCRCPRGFRGPDCSLPDPCLSS-PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 119
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATC 452
DEC PC + C NT G + C C AG+TG CE C C +G TC
Sbjct: 120 DECRVGE-------PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 172
Query: 453 IDLVD-DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
D + CAC G+ G+ C ++VDDC C NGG CVD +N Y C CP ++G C
Sbjct: 173 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 232
Query: 512 DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
+D D C P C NG C+ + C C GWTG++C+Q + C
Sbjct: 233 EDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI--------------DDC 278
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
A +C +G TC R C + +
Sbjct: 279 ATAVCFHGATC-----HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG 333
Query: 630 GWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C C G TG C+ +D C G++PC + GRCV G ++C+C G+TG C V+
Sbjct: 334 RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 393
Score = 219 bits (536), Expect = 3e-56
Identities = 156/536 (29%), Positives = 213/536 (39%), Gaps = 73/536 (13%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRCD---RPGDCDCRPGWRGELCSQ----CQPYPG 248
C PG+ G +CE+ P C G C C CRPG+ G C C P
Sbjct: 872 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 931
Query: 249 CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G C+ + + CTC ++ G C +++C + +PCQ+GG C T +C C G
Sbjct: 932 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWC-SRQPCQNGGRCVQTGA---YCLCPPG 987
Query: 307 FSGVDCERVDNPCAPQPCAHGT-----CSLAGTT----RGFTCTCDRGWGGXXXXXXXXX 357
+SG C+ PC G C G C C G G
Sbjct: 988 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP 1047
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
+ PC HG +CR ++ G+ CEC G+ G C +DVDEC+ + PC + +C +
Sbjct: 1048 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQ--------PCQHGGSCID 1099
Query: 418 TAGGYSCACLAGWTGRDCETNVDDC-------TG-QCLHGATCIDLVDDFHCACAAGYAG 469
Y C+C G G CE N DDC +G +CLH TC+DLV F C C GY G
Sbjct: 1100 LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1159
Query: 470 RTCSLDVDDCAPRPC--TNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
C D+++C C + +C+ D +RC+C GFSG C+ C PC +G
Sbjct: 1160 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGG 1219
Query: 527 ACYTAQS-----DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C + + CHCA + G C +R AR C E C G C
Sbjct: 1220 QCRPSPGPGGGLTFTCHCAQPFWGPRC-ERVARS-------------CRELQCPVGVPCQ 1265
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA----GGTCLPSALPPGWACGCRE 637
+ R S A GG+C P+ L P + C C +
Sbjct: 1266 QTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1325
Query: 638 GRTGALCE--LSLDLCGSSPCRNGGRCVGGSGWWMC--ECVA---GWTGETCAVRV 686
G TG CE + P C G C EC + GW G C++ V
Sbjct: 1326 GWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSV 1381
Score = 194 bits (473), Expect = 1e-48
Identities = 143/458 (31%), Positives = 179/458 (39%), Gaps = 61/458 (13%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHY--SCTPDGDKHCLPGWQGDNCEKPV--CKEGC 216
LC+P Y C C R G + P CL + G C+ V C
Sbjct: 909 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 968
Query: 217 HPTHGRCDRPGD-CDCRPGWRGELCS----QCQPYPG---------CKHG-YC--NGSSW 259
GRC + G C C PGW G LC C+ C+ G C SS
Sbjct: 969 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1028
Query: 260 DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C G C+Q+++ C +PCQHGGTC Y C C G++G +CE + C
Sbjct: 1029 YCVCPEGRTGSHCEQEVDPC-LAQPCQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDEC 1086
Query: 320 APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLHGASCRDH 372
A QPC HG + R + C+C G G GP CLH +C D
Sbjct: 1087 ASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1145
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ GF C C G+TG C D++EC RS GA + GG+ C C AG++G
Sbjct: 1146 VGGFRCTCPPGYTGLRCEADINEC--RS---GACHAAHTRDCLQDPGGGFRCLCHAGFSG 1200
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDD-----FHCACAAGYAGRTCSLDVDDCAPRPCTN 486
C+T + C Q C HG C F C CA + G C C C
Sbjct: 1201 PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPV 1260
Query: 487 GGECVDLLNAYRCICPVGFSGTNCED--------DRDHCAGSPCGNGAACYTA--QSDYY 536
G C RC CP G SG +C CA +PC +G +C A +
Sbjct: 1261 GVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFR 1320
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C CA GWTG C AA V E RC C
Sbjct: 1321 CACAQGWTGPRCEAPAAAPE------VSEEPRCPRAAC 1352
Score = 111 bits (268), Expect = 9e-24
Identities = 113/383 (29%), Positives = 138/383 (36%), Gaps = 58/383 (15%)
Query: 183 DKFGHYSCT-PDGDKHCLPGWQGDNCEK-PVCKEGCHPTH-GRC-DRPGD--CDCRPGWR 236
D Y C+ P G L D+C P G H G C D G C C PG+
Sbjct: 1099 DLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1158
Query: 237 GELCSQCQPYPGCKHGYCN-----------GSSWDCTCDTNWGGILCDQDLNYCGTHEPC 285
G C C+ G C+ G + C C + G C L+ C + +PC
Sbjct: 1159 GLRCEA--DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES-QPC 1215
Query: 286 QHGGTCE-NTAPD---QYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
QHGG C + P + C CA+ F G CERV C C G T RG C
Sbjct: 1216 QHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV-PCQQTPRGPRCA 1274
Query: 342 CD--------RGWGGXXXXXXXXXXASGPCLHGASCRDH--LDGFTCECADGWTGPACAE 391
C R + G A+ PCLHG SCR F C CA GWTGP C
Sbjct: 1275 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA 1334
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSC--ACLA---GWTGRDCETNVDDCTGQC 446
+ E + P AAC G C C + GW G DC +V D QC
Sbjct: 1335 PA------AAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1388
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
C L ++ C A + C D DC GG Y C F+
Sbjct: 1389 -EALQCWRLFNNSRCDPAC--SSPACLYDNFDCHA-----GGRERTCNPVYEKYCADHFA 1440
Query: 507 GTNCEDDRDHCAGSPCG-NGAAC 528
C+ C CG +G C
Sbjct: 1441 DGRCDQG---CNTEECGWDGLDC 1460
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 307 bits (754), Expect = 1e-82
Identities = 171/505 (33%), Positives = 224/505 (44%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCE-KPVCKEGCHPTHGRCDRP-------GDCDCRPGWRGELCSQCQP--YP 247
C PGW G+ C+ + C G G C C C G+RG CS P
Sbjct: 70 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 129
Query: 248 GCKHG-YCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C HG C+ + C+C + G C D++ C EPC+HGGTC NT P + C+C
Sbjct: 130 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-PGSFRCQC 188
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
G++G CE PCAP PC + GTC +G + C C G+ G
Sbjct: 189 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT-YDCACLPGFEGQNCEVNVDDCPGHR 247
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
CL+G +C D ++ + C+C WTG C EDVDEC + C N C NT GG+
Sbjct: 248 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP------NACHNGGTCFNTLGGH 301
Query: 423 SCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
SC C+ GWTG C N+DDC T C HGATC D V F+CAC G G C LD D C
Sbjct: 302 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVS 360
Query: 482 RPCTNGGEC-VDLLNAYR-CICPVGFSGTNCEDDRDHCA--GSPCGNGAACYTAQSDYYC 537
PC C + +N C CP GF+G C+ D D C+ +PC + C Q + C
Sbjct: 361 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 420
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG C + C G C N TC+ G +
Sbjct: 421 QCGRGYTGPRCE--------------TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 466
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ GG C G++C C G +G+ C+L +D C S+PCR
Sbjct: 467 TYCEVDIDECQSSPCVN----GGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCR 520
Query: 658 NGGRCVGGSGWWMCECVAGWTGETC 682
NG +CV + C C G+ G C
Sbjct: 521 NGAKCVDQPDGYECRCAEGFEGTLC 545
Score = 291 bits (713), Expect = 1e-77
Identities = 182/546 (33%), Positives = 245/546 (44%), Gaps = 55/546 (10%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSC--TPDGDK-HCLPGWQGDNCEKPV--CKEGC 216
C P Y +C + CR + +C TP + C G+ G CE P C
Sbjct: 149 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP 208
Query: 217 HPTHGRCDRPGD----CDCRPGWRGELCS----QCQPYPGCKHGYC-NG-SSWDCTCDTN 266
G C + GD C C PG+ G+ C C + G C +G ++++C C
Sbjct: 209 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE 268
Query: 267 WGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA 325
W G C +D++ C C +GGTC NT + C C G++G C + + CA C
Sbjct: 269 WTGQFCTEDVDECQLQPNACHNGGTCFNTLGG-HSCVCVNGWTGESCSQNIDDCATAVCF 327
Query: 326 HG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH-LDGFT-CECAD 382
HG TC F C C G G S PC A C + ++G C C
Sbjct: 328 HGATCH--DRVASFYCACPMGKTGLLCHLDDAC-VSNPCHEDAICDTNPVNGRAICTCPP 384
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G+TG AC +DVDECS GA PC + C NT G + C C G+TG CET+V++C
Sbjct: 385 GFTGGACDQDVDECS-----IGA-NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 438
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+G C + ATC+D + F C C AG+ G C +D+D+C PC NGG C D +N + C C
Sbjct: 439 LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC 498
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P GFSG+ C+ D D CA +PC NGA C Y C CA G+ G C R+ CS
Sbjct: 499 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD----RNVDDCSP 554
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
RC +G+ + C R + GG
Sbjct: 555 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP---------------CRHGGK 599
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGET 681
CL L + C C G TG CE+++D C S+PC G C G + C C G+TG
Sbjct: 600 CLD--LVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPL 656
Query: 682 CAVRVS 687
C V ++
Sbjct: 657 CNVEIN 662
Score = 290 bits (712), Expect = 1e-77
Identities = 170/502 (33%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT---HGR-C-DRPGD--CDCRPGWRGELC---SQCQPYP 247
C+ GW G++C + + + C HG C DR C C G G LC C P
Sbjct: 305 CVNGWTGESCSQNI--DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 362
Query: 248 GCKHGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
+ C+ + + CTC + G CDQD++ C PC+H G C NT + C+
Sbjct: 363 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ-GSFLCQ 421
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G++G CE N C PC + L + FTC C G+ G S P
Sbjct: 422 CGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTCICMAGFTGTYCEVDIDECQSSP 480
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C++G C+D ++GF+C C G++G C DVDEC+ PC N A C + GY
Sbjct: 481 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST--------PCRNGAKCVDQPDGY 532
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G+ G C+ NVDDC+ H C+D + F CACA GY G C VD+C +
Sbjct: 533 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 592
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
PC +GG+C+DL++ Y C CP G +G NCE + D CA +PC G C + Y C C PG
Sbjct: 593 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPG 651
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C+V + E CA C GG+CV E +R
Sbjct: 652 FTG-----------PLCNVEINE---CASSPCGEGGSCVDGENGFRCLCPPGSL-----P 692
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL--DLCGSSPCRNGG 660
+ G C + P G+ C C G +G C SL D C S PCR GG
Sbjct: 693 PLCLPPSHPCAHEPCSHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 750
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
C + C C G G C
Sbjct: 751 TCSSDGMGFHCTCPPGVQGRQC 772
Score = 287 bits (704), Expect = 1e-76
Identities = 165/509 (32%), Positives = 226/509 (44%), Gaps = 58/509 (11%)
Query: 195 DKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS---- 241
D CLPG++G NCE V + C P H RC G +C C P W G+ C+
Sbjct: 224 DCACLPGFEGQNCEVNV--DDC-PGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 279
Query: 242 QCQPYPGCKH--GYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+CQ P H G C + C C W G C Q+++ C T C HG TC +
Sbjct: 280 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDRVA- 337
Query: 298 QYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
++C C G +G+ C +D+ C PC C CTC G+ G
Sbjct: 338 SFYCACPMGKTGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD 396
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+ G PC H C + F C+C G+TGP C DV+EC GPC N A
Sbjct: 397 ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS--------GPCRNQAT 448
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C + G ++C C+AG+TG CE ++D+C + C++G C D V+ F C C +G++G TC
Sbjct: 449 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 508
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
LDVD+CA PC NG +CVD + Y C C GF GT C+ + D C+ PC +G C +
Sbjct: 509 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIA 567
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+ C CAPG+TG C + + C C +GG C+ +
Sbjct: 568 SFSCACAPGYTGTRCESQV--------------DECRSQPCRHGGKCLDLVDKYLCRCPS 613
Query: 594 XXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGS 653
+ G C + C C+ G TG LC + ++ C S
Sbjct: 614 GTTGVNCEVNIDDCASNPCTF-----GVCRDGI--NRYDCVCQPGFTGPLCNVEINECAS 666
Query: 654 SPCRNGGRCVGGSGWWMCECVAGWTGETC 682
SPC GG CV G + C C G C
Sbjct: 667 SPCGEGGSCVDGENGFRCLCPPGSLPPLC 695
Score = 281 bits (688), Expect = 1e-74
Identities = 168/522 (32%), Positives = 227/522 (43%), Gaps = 61/522 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTH--GRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE V + P G+C D C C G G C C P
Sbjct: 573 CAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNP- 631
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
C G C + +DC C + G LC+ ++N C + PC GG+C + + + C C G
Sbjct: 632 CTFGVCRDGINRYDCVCQPGFTGPLCNVEINECAS-SPCGEGGSCVD-GENGFRCLCPPG 689
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGPCL 364
C +PCA +PC+HG C A GF C C+ GW G A S PC
Sbjct: 690 SLPPLCLPPSHPCAHEPCSHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCR 747
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GR-----------SMTEGAL 406
G +C GF C C G G C E + C+ GR S +G
Sbjct: 748 AGGTCSSDGMGFHCTCPPGVQGRQC-ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 806
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAG 466
PC+N +C + G +SC+CL G+ G C +VD+C TC D V F C C G
Sbjct: 807 DPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPG 866
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
Y G C D+ DC+P C NGG CVD +N++ C+C G++G +C+ + D C PC +G
Sbjct: 867 YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGG 926
Query: 527 ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG- 585
C A + C C +TG C LV+ C+ C NGG CV+
Sbjct: 927 VCSAAHPGFRCTCLESFTGPQC-----------QTLVDW---CSRQPCQNGGRCVQTGAY 972
Query: 586 -----SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
W ++ QAGG C+ C C EGRT
Sbjct: 973 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLC--QAGGQCVDE--DSSHYCVCPEGRT 1028
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G+ CE +D C + PC++GG C G G +MCEC+ G+ G+ C
Sbjct: 1029 GSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1070
Score = 280 bits (686), Expect = 2e-74
Identities = 161/501 (32%), Positives = 218/501 (43%), Gaps = 52/501 (10%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRGELC----SQCQPYPG 248
C PG+ G C + C G C + C C PG LC C P
Sbjct: 648 CQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEP- 706
Query: 249 CKHGYCNGS--SWDCTCDTNWGGILCDQDL--NYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C HG C + + C C+ W G C Q L + C + +PC+ GGTC + + C C
Sbjct: 707 CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACES-QPCRAGGTCSSDGMG-FHCTCP 764
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
G G CE + +PC P PC HG + + C+C +GW PCL
Sbjct: 765 PGVQGRQCELL-SPCTPNPCEHGGRCESAPGQLPVCSCPQGW-------------QDPCL 810
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC+D + F+C C G+ GP CA DVDEC PC C + ++C
Sbjct: 811 NGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSN--------PC-GPGTCTDHVASFTC 861
Query: 425 ACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C G+ G CE ++ DC+ C +G TC+D V+ F C C GY G C + D C RP
Sbjct: 862 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP 921
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C +GG C +RC C F+G C+ D C+ PC NG C Q+ YC C PGW
Sbjct: 922 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCPPGW 979
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
+G+ C R+ R+ + + E+ +C GG CV E+ S S
Sbjct: 980 SGRLCDIRSLPCREAAAQIGVRLEQ----LCQAGGQCVDEDSS----HYCVCPEGRTGSH 1031
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q GGTC G+ C C G G CE +D C S PC++GG C+
Sbjct: 1032 CEQEVDPCLAQPCQHGGTC--RGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCI 1089
Query: 664 GGSGWWMCECVAGWTGETCAV 684
++C C G G C +
Sbjct: 1090 DLVARYLCSCPPGTLGVLCEI 1110
Score = 271 bits (665), Expect = 7e-72
Identities = 168/519 (32%), Positives = 226/519 (43%), Gaps = 53/519 (10%)
Query: 189 SCTPDGDK--HCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPGD--CDCRPGWRGELC 240
S PDG C PG+QG +C V C+ G HG C + PG C C G+ G LC
Sbjct: 138 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 197
Query: 241 SQ----CQPYPGCKHGYCNGS---SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCEN 293
C P P G C S ++DC C + G C+ +++ C H C +GGTC +
Sbjct: 198 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVD 256
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ Y C+C ++G C + C QP A H + T G +C C GW G
Sbjct: 257 GV-NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 315
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
A+ C HGA+C D + F C C G TG C D D C PC
Sbjct: 316 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSN--------PCHED 366
Query: 413 AACN-NTAGGYS-CACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
A C+ N G + C C G+TG C+ +VD+C+ C H C++ F C C GY
Sbjct: 367 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 426
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
G C DV++C PC N C+D + + CIC GF+GT CE D D C SPC NG
Sbjct: 427 TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 486
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + C C G++G TC + V+E CA C NG CV + +
Sbjct: 487 CKDRVNGFSCTCPSGFSGS-----------TCQLDVDE---CASTPCRNGAKCVDQPDGY 532
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
D G C+ ++C C G TG CE
Sbjct: 533 ECRCAEGFEGTLCDRNVDDCSPDPCHH-----GRCVDGIA--SFSCACAPGYTGTRCESQ 585
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PCR+GG+C+ ++C C +G TG C V +
Sbjct: 586 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI 624
Score = 250 bits (612), Expect = 2e-65
Identities = 138/435 (31%), Positives = 191/435 (43%), Gaps = 38/435 (8%)
Query: 261 CTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERVD 316
C C W G C +D + G PC G C+++ ++ CRC GF G DC D
Sbjct: 68 CLCPPGWVGERCQLEDPCHSG---PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD 124
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDG 375
PC PCAHG G F C+C G+ G G PC HG +C +
Sbjct: 125 -PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 183
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRD 434
F C+C G+TGP C C A PC N C + Y CACL G+ G++
Sbjct: 184 FRCQCPAGYTGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCACLPGFEGQN 235
Query: 435 CETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECV 491
CE NVDDC G +CL+G TC+D V+ ++C C + G+ C+ DVD+C P C NGG C
Sbjct: 236 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF 295
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
+ L + C+C G++G +C + D CA + C +GA C+ + +YC C G TG
Sbjct: 296 NTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTG------ 349
Query: 552 AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXX 611
+L + C C C + R
Sbjct: 350 ---------LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 400
Query: 612 XXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMC 671
+ G C+ + + C C G TG CE ++ C S PCRN C+ G + C
Sbjct: 401 GANPCEHLGRCVNT--QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 458
Query: 672 ECVAGWTGETCAVRV 686
C+AG+TG C V +
Sbjct: 459 ICMAGFTGTYCEVDI 473
Score = 244 bits (597), Expect = 1e-63
Identities = 157/504 (31%), Positives = 208/504 (41%), Gaps = 51/504 (10%)
Query: 204 GDNCEKPVCKEGCHPTHG-RC----DRPGDCDCRPGWRGELCS---QCQPYPGCKHGYCN 255
G P C +G +G RC R C C PGW GE C C P G C
Sbjct: 38 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ 97
Query: 256 GS------SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S + C C + G C + C PC HG C ++ C C G+ G
Sbjct: 98 SSVVAGTARFSCRCPRGFRGPDCSLP-DPC-LSSPCAHGARCSVGPDGRFLCSCPPGYQG 155
Query: 310 VDCER-VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
C VD +PC HG L T F C C G+ G A PC +G +
Sbjct: 156 RSCRSDVDECRVGEPCRHGGTCL-NTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 214
Query: 369 CRDHLD-GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
CR D + C C G+ G C +VD+C G C+N C + Y+C C
Sbjct: 215 CRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR--------CLNGGTCVDGVNTYNCQCP 266
Query: 428 AGWTGRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
WTG+ C +VD+C Q C +G TC + + C C G+ G +CS ++DDCA C
Sbjct: 267 PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVC 326
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPG 542
+G C D + ++ C CP+G +G C D D C +PC A C T C C PG
Sbjct: 327 FHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPG 385
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+TG C Q D CS+ C + G CV +GS+ ++
Sbjct: 386 FTGGACDQ----DVDECSI--------GANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET 433
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC 662
QA TCL + C C G TG CE+ +D C SSPC NGG C
Sbjct: 434 --DVNECLSGPCRNQA--TCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 487
Query: 663 VGGSGWWMCECVAGWTGETCAVRV 686
+ C C +G++G TC + V
Sbjct: 488 KDRVNGFSCTCPSGFSGSTCQLDV 511
Score = 241 bits (589), Expect = 1e-62
Identities = 139/420 (33%), Positives = 185/420 (44%), Gaps = 40/420 (9%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGTCS---LAGT 334
C PC +GG C + C C G+ G C+ +++PC PCA G C +AGT
Sbjct: 46 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 104
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDV 393
R F+C C RG+ G +S PC HGA C DG F C C G+ G +C DV
Sbjct: 105 AR-FSCRCPRGFRGPDCSLPDPCLSS-PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 162
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATC 452
DEC PC + C NT G + C C AG+TG CE C C +G TC
Sbjct: 163 DECRVGE-------PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 215
Query: 453 IDLVD-DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
D + CAC G+ G+ C ++VDDC C NGG CVD +N Y C CP ++G C
Sbjct: 216 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 275
Query: 512 DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
+D D C P C NG C+ + C C GWTG++C+Q + C
Sbjct: 276 EDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI--------------DDC 321
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
A +C +G TC R C + +
Sbjct: 322 ATAVCFHGATC-----HDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNG 376
Query: 630 GWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C C G TG C+ +D C G++PC + GRCV G ++C+C G+TG C V+
Sbjct: 377 RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 436
Score = 239 bits (584), Expect = 5e-62
Identities = 163/549 (29%), Positives = 222/549 (40%), Gaps = 63/549 (11%)
Query: 164 LCQPNYYNTTCTTF-----CRPRDDKFGHYSCTPDG-DKHCL--PGWQGDNCE--KPVCK 213
+C+P + C+ C + + G +C+ DG HC PG QG CE P
Sbjct: 722 VCEPGWSGPRCSQSLARDACESQPCRAGG-TCSSDGMGFHCTCPPGVQGRQCELLSPCTP 780
Query: 214 EGCHPTHGRCDR-PGD---CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C GRC+ PG C C GW+ C C+ G S+ C+C + G
Sbjct: 781 NPCEHG-GRCESAPGQLPVCSCPQGWQ----DPCLNGGSCQDGV---GSFSCSCLPGFAG 832
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTC 329
C +D++ C ++ PC G ++ A + C C G+ G CE+ C+P C +G
Sbjct: 833 PRCARDVDECLSN-PCGPGTCTDHVA--SFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGT 889
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
+ G F+C C G+ G S PCLHG C GF C C + +TGP C
Sbjct: 890 CVDGVN-SFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 948
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---- 445
VD CS + PC N C T G Y C C GW+GR C+ C
Sbjct: 949 QTLVDWCSRQ--------PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQI 998
Query: 446 -------CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
C G C+D +C C G G C +VD C +PC +GG C + Y
Sbjct: 999 GVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYM 1058
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C C G++G NCEDD D CA PC +G +C + Y C C PG G C D
Sbjct: 1059 CECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLC--EINEDDCG 1116
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
++ R C + GTCV G +R ++
Sbjct: 1117 PGPPLDSGPR-----CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR 1171
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC-----VGGSGWWMCEC 673
CL G+ C C G +G C+ L C S PC++GG+C GG + C C
Sbjct: 1172 --DCLQDP-GGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC 1228
Query: 674 VAGWTGETC 682
+ G C
Sbjct: 1229 AQPFWGPRC 1237
Score = 238 bits (582), Expect = 8e-62
Identities = 163/518 (31%), Positives = 213/518 (41%), Gaps = 68/518 (13%)
Query: 183 DKFGHYSCT-PDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC-DRPG--DCDCRPGWRGE 238
D+ +SCT P G D C C+ G +C D+P +C C G+ G
Sbjct: 489 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA-----KCVDQPDGYECRCAEGFEGT 543
Query: 239 LCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
LC + C P P C HG C +G +S+ C C + G C+ ++ C + +PC+HGG C
Sbjct: 544 LCDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRS-QPCRHGGKCL 601
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ D+Y CRC G +GV+CE + CA PC G C G R + C C G+ G
Sbjct: 602 DLV-DKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR-DGINR-YDCVCQPGFTGPLCN 658
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
AS PC G SC D +GF C C G P C C+ PC +
Sbjct: 659 VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHE--------PCSHG 710
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNV--DDCTGQ-CLHGATCIDLVDDFHCACAAGYAG 469
C + GG+ C C GW+G C ++ D C Q C G TC FHC C G G
Sbjct: 711 I-CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQG 769
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYR-CICPVGFSGTNCEDDRDHCAGSPCGNGAAC 528
R C L + C P PC +GG C C CP G+ PC NG +C
Sbjct: 770 RQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ-------------DPCLNGGSC 815
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C PG+ G C ARD V+E C C G TC S+
Sbjct: 816 QDGVGSFSCSCLPGFAGPRC----ARD-------VDE---CLSNPCGPG-TCTDHVASFT 860
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
+ GGTC+ ++C CR G TGA C+
Sbjct: 861 CTCPPGYGGFHCEQDLPDCSPSSCFN----GGTCVDGV--NSFSCLCRPGYTGAHCQHEA 914
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
D C S PC +GG C + C C+ +TG C V
Sbjct: 915 DPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLV 952
Score = 232 bits (568), Expect = 4e-60
Identities = 196/685 (28%), Positives = 254/685 (37%), Gaps = 107/685 (15%)
Query: 164 LCQPNYYNTTCTTFCRP-RDDKFGHYSCTPDGDKH----CLPGWQGDNC---EKPVCKEG 215
+CQP + C G DG+ C PG C P E
Sbjct: 647 VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEP 706
Query: 216 CHPTHGRC-DRPGD--CDCRPGWRGELCSQ------CQPYPGCKHGYCN--GSSWDCTCD 264
C +HG C D PG C C PGW G CSQ C+ P G C+ G + CTC
Sbjct: 707 C--SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCP 764
Query: 265 TNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC 324
G C+ L+ C T PC+HGG CE+ C C +G+ PC
Sbjct: 765 PGVQGRQCEL-LSPC-TPNPCEHGGRCESAPGQLPVCSCPQGWQ-------------DPC 809
Query: 325 AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
+G G F+C+C G+ G S PC G +C DH+ FTC C G+
Sbjct: 810 LNGGSCQDGVG-SFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGY 867
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG 444
G C +D+ +CS S C N C + +SC C G+TG C+ D C
Sbjct: 868 GGFHCEQDLPDCSPSS--------CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS 919
Query: 445 Q-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPV 503
+ CLHG C F C C + G C VD C+ +PC NGG CV AY C+CP
Sbjct: 920 RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPP 977
Query: 504 GFSGTNCEDDRDHCAGSP----------CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
G+SG C+ C + C G C S +YC C G TG +C Q
Sbjct: 978 GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ--- 1034
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
E + C C +GGTC G + +
Sbjct: 1035 -----------EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC- 1082
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNGGRCVGGS 666
Q GG+C+ L + C C G G LCE++ D CG P C + G CV
Sbjct: 1083 ---QHGGSCID--LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLV 1137
Query: 667 GWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAAR 726
G + C C G+TG C ++ RCLC A +
Sbjct: 1138 GGFRCTCPPGYTGLRCEADIN---ECRSGACHAAHTRDCLQDPGGGFRCLCHA--GFSGP 1192
Query: 727 RCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDG-PGACGVANGTWWWGCNACWCSG 785
RC ++ E+ Q HG RP P G G C A +WG C
Sbjct: 1193 RCQTVLSPCES--------QPCQHGGQCRPSPGPGGGLTFTCHCAQP--FWGPR---CER 1239
Query: 786 GVPTCTRLWC--GLPDCLAPNAQPC 808
+C L C G+P P C
Sbjct: 1240 VARSCRELQCPVGVPCQQTPRGPRC 1264
Score = 190 bits (462), Expect = 3e-47
Identities = 117/380 (30%), Positives = 153/380 (40%), Gaps = 34/380 (8%)
Query: 198 CLPGWQGDNCEK---PVCKEGC-HPTHGRCDRPG-DCDCRPGWRGELCSQ----CQPYPG 248
C PG+ G +C+ P C H PG C C + G C C P
Sbjct: 901 CRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC 960
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT---------HEPCQHGGTCENTAPDQY 299
G C + C C W G LCD C + CQ GG C + Y
Sbjct: 961 QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1020
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G CE+ +PC QPC HG TC G G+ C C G+ G
Sbjct: 1021 -CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR--GYMGGYMCECLPGYNGDNCEDDVDEC 1077
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNN 417
AS PC HG SC D + + C C G G C + D+C + GP C++ C +
Sbjct: 1078 ASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS--GPRCLHNGTCVD 1135
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDD----FHCACAAGYAGRTCS 473
GG+ C C G+TG CE ++++C H A D + D F C C AG++G C
Sbjct: 1136 LVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQ 1195
Query: 474 LDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC 528
+ C +PC +GG+C + C C F G CE C C G C
Sbjct: 1196 TVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC 1255
Query: 529 YTAQSDYYCHCAPGWTGKNC 548
C C PG +G +C
Sbjct: 1256 QQTPRGPRCACPPGLSGPSC 1275
Score = 168 bits (409), Expect = 7e-41
Identities = 121/384 (31%), Positives = 153/384 (39%), Gaps = 45/384 (11%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHY--SCTPDGDKHCLPGWQGDNCEKPV--CKEGC 216
LC+P Y C C R G + P CL + G C+ V C
Sbjct: 900 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 959
Query: 217 HPTHGRCDRPGD-CDCRPGWRGELCS----QCQPYPG---------CKHG-YC--NGSSW 259
GRC + G C C PGW G LC C+ C+ G C SS
Sbjct: 960 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1019
Query: 260 DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C G C+Q+++ C +PCQHGGTC Y C C G++G +CE + C
Sbjct: 1020 YCVCPEGRTGSHCEQEVDPC-LAQPCQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDEC 1077
Query: 320 APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLHGASCRDH 372
A QPC HG + R + C+C G G GP CLH +C D
Sbjct: 1078 ASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1136
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ GF C C G+TG C D++EC RS GA + GG+ C C AG++G
Sbjct: 1137 VGGFRCTCPPGYTGLRCEADINEC--RS---GACHAAHTRDCLQDPGGGFRCLCHAGFSG 1191
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDD-----FHCACAAGYAGRTCSLDVDDCAPRPCTN 486
C+T + C Q C HG C F C CA + G C C C
Sbjct: 1192 PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPV 1251
Query: 487 GGECVDLLNAYRCICPVGFSGTNC 510
G C RC CP G SG +C
Sbjct: 1252 GVPCQQTPRGPRCACPPGLSGPSC 1275
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 303 bits (745), Expect = 1e-81
Identities = 166/531 (31%), Positives = 238/531 (44%), Gaps = 55/531 (10%)
Query: 178 CRPRDDKFGHYSCTPDGD-KH---CLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGD 228
C P + G +C P GD H CLPG+ G NCE+ + C G C +
Sbjct: 222 CSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
Query: 229 CDCRPGWRGELCS----QCQPYP-GCKH-GYCNGS--SWDCTCDTNWGGILCDQDLNYCG 280
C C P W G+ C+ +CQ P C++ G C+ + ++C C W G C ++++ C
Sbjct: 281 CPCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFT 339
+ C HG TC + ++C C G +G+ C +++ C PC G+ C
Sbjct: 341 S-AACFHGATCHDRVA-SFYCECPHGRTGLLC-HLNDACISNPCNEGSNCDTNPVNGKAI 397
Query: 340 CTCDRGWGGXXXXXXXXXXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
CTC G+ G + G PC H C + L F C+C G+TGP C DV+EC
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC- 456
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLV 456
PC N A C + G + C C+ G+ G CE N D+C + CLH C+D +
Sbjct: 457 -------VSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKI 509
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
++F C C G+ G C DVD+CA PC NG +C+D N Y C+C G++GT+CE D D
Sbjct: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C PC G +C + + C C PG+TG +C C+ C
Sbjct: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNI--------------NECSSQPCRL 614
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
GTC + ++ + GTCL G+ C C
Sbjct: 615 RGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCD-----SGTCLDKI--DGYECACE 667
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G TG++C ++D C +PC NGG C G + C C G+ TC V+
Sbjct: 668 PGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 300 bits (736), Expect = 2e-80
Identities = 175/564 (31%), Positives = 238/564 (42%), Gaps = 62/564 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH----CLPGWQGDNCEKPVCKEGCHPT 219
+C Y T C D HY DG C PG+ G +CE + + P
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Query: 220 H--GRCDRPGD---CDCRPGWRGELCS----QCQPYPGCKHGYCNGS--SWDCTCDTNWG 268
G C P + C C G G C C P C G C ++C C+ +
Sbjct: 613 RLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT 671
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
G +C+ +++ C + PC +GGTCE+ + + CRC EG+ C N C PC HG
Sbjct: 672 GSMCNSNIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C + G+ C CD GW G S PC++G +C+D G C C +G++GP
Sbjct: 730 CR--DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPN 787
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCL 447
C +++EC A PC+N C + GY C CL +TG CE + C C
Sbjct: 788 CQTNINEC--------ASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 448 HGATCIDLVD--DFHCAC-AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
+G C D F C C AG G+TC +D+++C PC +G C + YRC C G
Sbjct: 840 NGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAG 899
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG-------KNCTQRAARDRK 557
+SG NCE D D C +PC NG +C + +C C PG+ G C R+
Sbjct: 900 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 959
Query: 558 TCSVLVE-----------------ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
C+ V+ + C E C NGGTCV S+
Sbjct: 960 NCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF----TCLCPPGFT 1015
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG 660
S GGTC C C +G TG C+ + C SSPC+NGG
Sbjct: 1016 GSYCQHVVNECDSRPCLLGGTCQDGR--GLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073
Query: 661 RCVGGSGWWMCECVAGWTGETCAV 684
+C + CEC +GWTG C V
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDV 1097
Score = 296 bits (727), Expect = 2e-79
Identities = 175/550 (31%), Positives = 236/550 (42%), Gaps = 67/550 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH--GRCD---RPGDCDCRPGWRG 237
DK Y C C PG+ G C + + +P H G C+ C C G+
Sbjct: 657 DKIDGYECA------CEPGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C HG C S + C CD W G CD + N C ++ PC +GGTC
Sbjct: 711 PTCLSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTC 768
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ C C EGFSG +C+ N CA PC + GTC G+ C C + G
Sbjct: 769 KDMTSG-IVCTCREGFSGPNCQTNINECASNPCLNKGTC--IDDVAGYKCNCLLPYTGAT 825
Query: 351 XXXXXXXXASGPCLHGASCRDHLD--GFTCECAD-GWTGPACAEDVDECSGRSMTEGALG 407
A PC +G CR D F+C C G G C D++EC L
Sbjct: 826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINEC--------VLS 877
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAG 466
PC + A+C NT G Y C C AG++GR+CET++DDC C +G +C D ++ C C G
Sbjct: 878 PCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG 937
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
+ G C D+++CA PC NG C D +++Y C CP GFSG +CE++ C S C NG
Sbjct: 938 FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 997
Query: 527 ACYTAQSDYYCHCAPGWTGK------------------NCTQRAARDRKTCSV------L 562
C + + C C PG+TG C R TC
Sbjct: 998 TCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNC 1057
Query: 563 VEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXX 616
C C NGG C + +R D
Sbjct: 1058 QNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC 1117
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
Q GG C+ + C C+ G TG+ CE +D C SPC+NG C G + C+CVAG
Sbjct: 1118 QHGGLCVDAG--NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAG 1175
Query: 677 WTGETCAVRV 686
+ G C+ +
Sbjct: 1176 YHGVNCSEEI 1185
Score = 289 bits (710), Expect = 3e-77
Identities = 169/540 (31%), Positives = 230/540 (42%), Gaps = 38/540 (7%)
Query: 165 CQPNYYNTTCTTFCRP-RDDKFGHYSCTP--DGDK-HCLPGWQGDNCE--KPVCKEGCHP 218
C Y++ TC + + H +C +G K C PGW G NC+ C+
Sbjct: 704 CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
Query: 219 THGRC-DRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYC--NGSSWDCTCDTNWGG 269
G C D C CR G+ G C ++C P G C + + + C C + G
Sbjct: 764 NGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTG 823
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYF-CRC-AEGFSGVDCERVDNPCAPQPCAHG 327
C+ L C PC++GG C + + F C C G G CE N C PC HG
Sbjct: 824 ATCEVVLAPCAP-SPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHG 882
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
S T + C C G+ G PC +G SC D ++ C+C G+ G
Sbjct: 883 A-SCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGT 941
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQC 446
C ED++EC A PC N A C + Y+C C AG++G CE N DCT C
Sbjct: 942 FCEEDINEC--------ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 993
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC+D ++ F C C G+ G C V++C RPC GG C D +RC CP G++
Sbjct: 994 FNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYT 1053
Query: 507 GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
G NC++ C SPC NG C+ + Y C C GWTG C + +C V +
Sbjct: 1054 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV----SCEVAAQRQ 1109
Query: 567 ERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSA 626
+C +GG CV + G+ S Q G TC
Sbjct: 1110 GVDVARLCQHGGLCV-DAGN---THHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL 1165
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
G++C C G G C +D C S PC+NGG C+ + C C G G C + V
Sbjct: 1166 --GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1223
Score = 280 bits (687), Expect = 2e-74
Identities = 162/521 (31%), Positives = 232/521 (44%), Gaps = 53/521 (10%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
CL G+ G CE V C C D+ G+ C C PG+ G C +C P
Sbjct: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPC 499
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
+G C + + C C T + G LC D++ C + PC++G C + P+ Y C C EG
Sbjct: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLD-GPNTYTCVCTEG 557
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
++G CE + C P PC +G+C T FTC C G+ G +S PC
Sbjct: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRLR 615
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+C+D + + C C G TGP C ++D+C A PC ++ C + GY CAC
Sbjct: 616 GTCQDPDNAYLCFCLKGTTGPNCEINLDDC--------ASSPC-DSGTCLDKIDGYECAC 666
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C +N+D+C G C +G TC D ++ F C C GY TC +V++C PC
Sbjct: 667 EPGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
+G C D LN Y+C C G+SGTNC+ + + C +PC NG C S C C G++G
Sbjct: 727 HGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSG 785
Query: 546 KN-------CTQRAARDRKTC---------SVLVEESER--------CAEGMCANGGTCV 581
N C ++ TC + L+ + CA C NGG C
Sbjct: 786 PNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC- 844
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
R+ + + G +C + + C C+ G +G
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTH--GXYRCHCQAGYSG 902
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CE +D C +PC NGG C G C+C+ G+ G C
Sbjct: 903 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFC 943
Score = 277 bits (678), Expect = 2e-73
Identities = 159/506 (31%), Positives = 223/506 (44%), Gaps = 49/506 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG--DCDCRPGWRGELC----SQCQPY 246
C G+ G C + V C G +P G+C + G +C C G+ G C ++C
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 247 PGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P C + C C + G+ C+ + + C + PC H G C + +++ C C
Sbjct: 460 PCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECAS-SPCLHNGRCLDKI-NEFQCECP 517
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF+G C+ + CA PC +G L G +TC C G+ G PC
Sbjct: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTCVCTEGYTGTHCEVDIDECDPDPCH 576
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC+D + FTC C G+TG C +++ECS + PC C + Y C
Sbjct: 577 YG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQ--------PCRLRGTCQDPDNAYLC 627
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
CL G TG +CE N+DDC TC+D +D + CAC GY G C+ ++D+CA PC
Sbjct: 628 FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPC 687
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C D +N + C CP G+ C + + C +PC +G AC + + Y C C PGW+
Sbjct: 688 HNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKCDCDPGWS 746
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G NC + +E C C NGGTC
Sbjct: 747 GTNCD-------------INNNE-CESNPCVNGGTC----KDMTSGIVCTCREGFSGPNC 788
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
GTC+ G+ C C TGA CE+ L C SPCRNGG C
Sbjct: 789 QTNINECASNPCLNKGTCIDDV--AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
Query: 665 GSGW--WMCEC-VAGWTGETCAVRVS 687
+ + C C AG G+TC V ++
Sbjct: 847 SEDYESFSCVCPTAGAKGQTCEVDIN 872
Score = 274 bits (671), Expect = 1e-72
Identities = 169/515 (32%), Positives = 223/515 (43%), Gaps = 54/515 (10%)
Query: 197 HCLPGWQGDNCEKPV--CKEG-CHPTHGRCD---RPGDCDCRPGWRGELC----SQCQPY 246
HC G+ G NCE + C+ CH G C CDC PG+RG C ++C
Sbjct: 895 HCQAGYSGRNCETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 953
Query: 247 PGCKHGY-CNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P C++G C S+ CTC + GI C+ + C T C +GGTC + + + C C
Sbjct: 954 P-CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGI-NSFTCLC 1010
Query: 304 AEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGF-TCTCDRGWGGXXXXXXXXXXASG 361
GF+G C+ V N C +PC GTC RG CTC +G+ G S
Sbjct: 1011 PPGFTGSYCQHVVNECDSRPCLLGGTCQ---DGRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTA 419
PC +G C + CEC GWTG C C + +G C + C +
Sbjct: 1068 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1127
Query: 420 GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
+ C C AG+TG CE VD+C+ C +GATC D + + C C AGY G CS ++D+
Sbjct: 1128 NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE 1187
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-------AGSP-CGNGAACYT 530
C PC NGG C+DL N Y+C CP G G +CE + D C + SP C N C
Sbjct: 1188 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVD 1247
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT--CVREEGSWR 588
Y C C PG+ G+ C + C C GT CV+ +
Sbjct: 1248 QVGGYSCTCPPGFVGERCEG--------------DVNECLSNPCDARGTQNCVQRVNDFH 1293
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-LPSALPPGWACGCREGRTGALCELS 647
+S + GGTC + S G+ C C G GA CE
Sbjct: 1294 CECRAGHTGRRCESVINGCKGKPC----KNGGTCAVASNTARGFICKCPAGFEGATCEND 1349
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CGS C NGG C+ G C C+ +TG C
Sbjct: 1350 ARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1384
Score = 273 bits (669), Expect = 2e-72
Identities = 158/500 (31%), Positives = 206/500 (41%), Gaps = 47/500 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQPYPGCKHGYCNG-- 256
+ C C+ G C THG C C+ G+ G C C+P P G C
Sbjct: 872 NECVLSPCRHGASCQNTHGXYR----CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGI 927
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
++ C C + G C++D+N C + +PC++G C + D Y C C GFSG+ CE
Sbjct: 928 NTAFCDCLPGFRGTFCEEDINECAS-DPCRNGANCTDCV-DSYTCTCPAGFSGIHCENNT 985
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C C +G + G FTC C G+ G S PCL G +C+D
Sbjct: 986 PDCTESSCFNGGTCVDGIN-SFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLH 1044
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TGP C V C PC N C T Y C C +GWTG C+
Sbjct: 1045 RCTCPQGYTGPNCQNLVHWCDS--------SPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1096
Query: 437 TNVDDC-----------TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C C HG C+D + HC C AGY G C VD+C+P PC
Sbjct: 1097 VPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQ 1156
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
NG C D L Y C C G+ G NC ++ D C PC NG C + Y C C G G
Sbjct: 1157 NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQG 1216
Query: 546 KNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXX 605
+C C+ V+ R + C N GTCV + G + +
Sbjct: 1217 VHCEINV----DDCNPPVDPVSRSPK--CFNNGTCVDQVGGYSCTCPPGFVGERCEG--- 1267
Query: 606 XXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG 665
A GT + C CR G TG CE ++ C PC+NGG C
Sbjct: 1268 -DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVA 1326
Query: 666 SG---WWMCECVAGWTGETC 682
S ++C+C AG+ G TC
Sbjct: 1327 SNTARGFICKCPAGFEGATC 1346
Score = 249 bits (609), Expect = 4e-65
Identities = 145/500 (29%), Positives = 216/500 (43%), Gaps = 48/500 (9%)
Query: 203 QGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCSQCQPYPG--CKH-GYCNG 256
+G C +P E C G+C+ C C + G C P CK+ G C+
Sbjct: 20 RGPRCSQP--GETCL-NGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 257 ------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
+ + C+C + G LC L+ PC++GGTC+ +Y CRC G+SG
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 311 DCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP--CLHGAS 368
C++ D PCA PCA+G L + C C + G P C HG +
Sbjct: 137 SCQQAD-PCASNPCANGGQCLPFEA-SYICHCPPSFHGPTCRQDVNECGQKPRLCRHGGT 194
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACL 427
C + + + C C TGP C CS PC N C T + CACL
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSP--------SPCQNGGTCRPTGDVTHECACL 246
Query: 428 AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPC 484
G+TG++CE N+DDC G C +G C+D V+ ++C C + G+ C+ DVD+C P C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C + Y C+C G++G +C ++ D CA + C +GA C+ + +YC C G T
Sbjct: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G +L ++ C C G C + +
Sbjct: 367 G---------------LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
+ G C+ + + C C +G TG CE+ ++ C S+PC+N C+
Sbjct: 412 DVDECSLGANPCEHAGKCINTL--GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 665 GSGWWMCECVAGWTGETCAV 684
G + C C+ G+ G C V
Sbjct: 470 QIGEFQCMCMPGYEGVHCEV 489
Score = 248 bits (608), Expect = 6e-65
Identities = 145/509 (28%), Positives = 213/509 (41%), Gaps = 51/509 (10%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRC---DRPGDCDCRPGWRGELCSQ----CQPYPG 248
C PGW G +C++ P C G+C + C C P + G C Q C P
Sbjct: 129 CPPGWSGKSCQQADPCASNPC-ANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPR 187
Query: 249 -CKH-GYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H G C+ S+ C C G C++ C + PCQ+GGTC T + C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-SPSPCQNGGTCRPTGDVTHECACL 246
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
GF+G +CE + C C +G + G + C C W G P
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCPCPPEWTGQYCTEDVDECQLMPNA 305
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C + G+ C C +GWTG C+E++D+C A C + A C++ +
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC--------ASAACFHGATCHDRVASF 357
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATC--IDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G TG C N + C G+ C + C C +GY G CS DVD+C+
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
PC + G+C++ L ++ C C G++G CE D + C +PC N A C ++ C
Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCM 477
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
C PG+ G +C ++ CA C + G C+ + ++
Sbjct: 478 CMPGYEGVHCE--------------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH 523
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRN 658
+ G CL P + C C EG TG CE+ +D C PC
Sbjct: 524 LCQ----YDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHY 577
Query: 659 GGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G C G + C C G+TG C ++
Sbjct: 578 GS-CKDGVATFTCLCRPGYTGHHCETNIN 605
Score = 226 bits (552), Expect = 3e-58
Identities = 162/552 (29%), Positives = 223/552 (40%), Gaps = 89/552 (16%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDK----HCLPGWQGDNCEKPV------ 211
CQ Y C T CRP G SCT DG CLPG++G CE+ +
Sbjct: 896 CQAGYSGRNCETDIDDCRPNPCHNGG-SCT-DGINTAFCDCLPGFRGTFCEEDINECASD 953
Query: 212 -CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYC-NG-------SSWDCT 262
C+ G + T C C C G+ G C P C C NG +S+ C
Sbjct: 954 PCRNGANCTD--CVDSYTCTCPAGFSGIHCENNTP--DCTESSCFNGGTCVDGINSFTCL 1009
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C +N C + PC GGTC++ + C C +G++G +C+ + + C
Sbjct: 1010 CPPGFTGSYCQHVVNECDSR-PCLLGGTCQD-GRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXX----------XXXXXXXXASGPCLHGASCRDH 372
PC +G T+ + C C GW G + C HG C D
Sbjct: 1068 PCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1126
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ C C G+TG C + VDECS PC N A C + GGYSC C+AG+ G
Sbjct: 1127 GNTHHCRCQAGYTGSYCEDLVDECSP--------SPCQNGATCTDYLGGYSCKCVAGYHG 1178
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR--------P 483
+C +D+C C +G TC+DL + + C+C G G C ++VDDC P
Sbjct: 1179 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK 1238
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-GNGAA-CYTAQSDYYCHCAP 541
C N G CVD + Y C CP GF G CE D + C +PC G C +D++C C
Sbjct: 1239 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1298
Query: 542 GWTGKNCTQ-------RAARDRKTCSVLVEESE----RCAEGM----------------C 574
G TG+ C + ++ TC+V + +C G C
Sbjct: 1299 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1358
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
NGGTC+ G + GTC P++ P + C
Sbjct: 1359 LNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCL 1416
Query: 635 CREGRTGALCEL 646
C G LC +
Sbjct: 1417 CPAKFNGLLCHI 1428
Score = 175 bits (426), Expect = 6e-43
Identities = 127/433 (29%), Positives = 176/433 (40%), Gaps = 63/433 (14%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPV------ 211
LC P + + C C R G +C H C G+ G NC+ V
Sbjct: 1009 LCPPGFTGSYCQHVVNECDSRPCLLGG-TCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 212 -CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQPYPG---------CKHG-YC 254
CK G C TH + C+C GW G C C+ C+HG C
Sbjct: 1068 PCKNGGKCWQTHTQYR----CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1123
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
G++ C C + G C+ ++ C PCQ+G TC + Y C+C G+ GV+C
Sbjct: 1124 VDAGNTHHCRCQAGYTGSYCEDLVDECSP-SPCQNGATCTDYLGG-YSCKCVAGYHGVNC 1181
Query: 313 ERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX--------XASGPC 363
+ C PC +G TC T + C+C RG G S C
Sbjct: 1182 SEEIDECLSHPCQNGGTCLDLPNT--YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1239
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
+ +C D + G++C C G+ G C DV+EC CV +
Sbjct: 1240 FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRV------NDFH 1293
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCI---DLVDDFHCACAAGYAGRTCSLDVDDC 479
C C AG TGR CE+ ++ C G+ C +G TC + F C C AG+ G TC D C
Sbjct: 1294 CECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC 1353
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHC-AGSPCGNGAACY-TAQSDYY 536
C NGG C+ + C+C F+G C+ C G+PC N C T++S +Y
Sbjct: 1354 GSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFY 1413
Query: 537 -CHCAPGWTGKNC 548
C C + G C
Sbjct: 1414 RCLCPAKFNGLLC 1426
Score = 101 bits (243), Expect = 1e-20
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 41/336 (12%)
Query: 205 DNCEKPVCKEGCHP---THGRC-DRPG--DCDCRPGWRGELC----SQCQPYPGCKHGYC 254
D+C PV P +G C D+ G C C PG+ GE C ++C P G
Sbjct: 1224 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQ 1283
Query: 255 NG----SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAPDQYFCRCAEGF 307
N + + C C G C+ +N C +PC++GGTC NTA + C+C GF
Sbjct: 1284 NCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPCKNGGTCAVASNTARG-FICKCPAGF 1341
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--PCLH 365
G CE C C +G ++G R TC C + G G PC +
Sbjct: 1342 EGATCENDARTCGSLRCLNGGTCISGP-RSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 1400
Query: 366 GASCRDHLDG--FTCECADGWTGPACA---EDVDECSGRSMTEGALGPCVNAAACNNTAG 420
+C + + C C + G C +GR + + C AG
Sbjct: 1401 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1460
Query: 421 GYSCA--C---LAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C+ C GW G DC N +D C C D HC AG C D
Sbjct: 1461 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG--CLFD 1518
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
DC G+C L + Y C FS +C+
Sbjct: 1519 GFDCQRAE----GQCNPLYDQY---CKDHFSDGHCD 1547
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 303 bits (745), Expect = 1e-81
Identities = 166/531 (31%), Positives = 238/531 (44%), Gaps = 55/531 (10%)
Query: 178 CRPRDDKFGHYSCTPDGD-KH---CLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGD 228
C P + G +C P GD H CLPG+ G NCE+ + C G C +
Sbjct: 222 CSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
Query: 229 CDCRPGWRGELCS----QCQPYP-GCKH-GYCNGS--SWDCTCDTNWGGILCDQDLNYCG 280
C C P W G+ C+ +CQ P C++ G C+ + ++C C W G C ++++ C
Sbjct: 281 CPCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFT 339
+ C HG TC + ++C C G +G+ C +++ C PC G+ C
Sbjct: 341 S-AACFHGATCHDRVA-SFYCECPHGRTGLLC-HLNDACISNPCNEGSNCDTNPVNGKAI 397
Query: 340 CTCDRGWGGXXXXXXXXXXASG--PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
CTC G+ G + G PC H C + L F C+C G+TGP C DV+EC
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC- 456
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLV 456
PC N A C + G + C C+ G+ G CE N D+C + CLH C+D +
Sbjct: 457 -------VSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKI 509
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
++F C C G+ G C DVD+CA PC NG +C+D N Y C+C G++GT+CE D D
Sbjct: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C PC G +C + + C C PG+TG +C C+ C
Sbjct: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNI--------------NECSSQPCRL 614
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
GTC + ++ + GTCL G+ C C
Sbjct: 615 RGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCD-----SGTCLDKI--DGYECACE 667
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G TG++C ++D C +PC NGG C G + C C G+ TC V+
Sbjct: 668 PGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 300 bits (736), Expect = 2e-80
Identities = 175/564 (31%), Positives = 238/564 (42%), Gaps = 62/564 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH----CLPGWQGDNCEKPVCKEGCHPT 219
+C Y T C D HY DG C PG+ G +CE + + P
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Query: 220 H--GRCDRPGD---CDCRPGWRGELCS----QCQPYPGCKHGYCNGS--SWDCTCDTNWG 268
G C P + C C G G C C P C G C ++C C+ +
Sbjct: 613 RLRGTCQDPDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYT 671
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
G +C+ +++ C + PC +GGTCE+ + + CRC EG+ C N C PC HG
Sbjct: 672 GSMCNSNIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C + G+ C CD GW G S PC++G +C+D G C C +G++GP
Sbjct: 730 CR--DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPN 787
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCL 447
C +++EC A PC+N C + GY C CL +TG CE + C C
Sbjct: 788 CQTNINEC--------ASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 448 HGATCIDLVD--DFHCAC-AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
+G C D F C C AG G+TC +D+++C PC +G C + YRC C G
Sbjct: 840 NGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAG 899
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG-------KNCTQRAARDRK 557
+SG NCE D D C +PC NG +C + +C C PG+ G C R+
Sbjct: 900 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 959
Query: 558 TCSVLVE-----------------ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
C+ V+ + C E C NGGTCV S+
Sbjct: 960 NCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF----TCLCPPGFT 1015
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG 660
S GGTC C C +G TG C+ + C SSPC+NGG
Sbjct: 1016 GSYCQHVVNECDSRPCLLGGTCQDGR--GLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073
Query: 661 RCVGGSGWWMCECVAGWTGETCAV 684
+C + CEC +GWTG C V
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDV 1097
Score = 296 bits (727), Expect = 2e-79
Identities = 175/550 (31%), Positives = 236/550 (42%), Gaps = 67/550 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTH--GRCD---RPGDCDCRPGWRG 237
DK Y C C PG+ G C + + +P H G C+ C C G+
Sbjct: 657 DKIDGYECA------CEPGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C HG C S + C CD W G CD + N C ++ PC +GGTC
Sbjct: 711 PTCLSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTC 768
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ C C EGFSG +C+ N CA PC + GTC G+ C C + G
Sbjct: 769 KDMTSG-IVCTCREGFSGPNCQTNINECASNPCLNKGTC--IDDVAGYKCNCLLPYTGAT 825
Query: 351 XXXXXXXXASGPCLHGASCRDHLD--GFTCECAD-GWTGPACAEDVDECSGRSMTEGALG 407
A PC +G CR D F+C C G G C D++EC L
Sbjct: 826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINEC--------VLS 877
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAG 466
PC + A+C NT G Y C C AG++GR+CET++DDC C +G +C D ++ C C G
Sbjct: 878 PCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG 937
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
+ G C D+++CA PC NG C D +++Y C CP GFSG +CE++ C S C NG
Sbjct: 938 FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 997
Query: 527 ACYTAQSDYYCHCAPGWTGK------------------NCTQRAARDRKTCSV------L 562
C + + C C PG+TG C R TC
Sbjct: 998 TCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNC 1057
Query: 563 VEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXX 616
C C NGG C + +R D
Sbjct: 1058 QNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC 1117
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
Q GG C+ + C C+ G TG+ CE +D C SPC+NG C G + C+CVAG
Sbjct: 1118 QHGGLCVDAG--NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAG 1175
Query: 677 WTGETCAVRV 686
+ G C+ +
Sbjct: 1176 YHGVNCSEEI 1185
Score = 289 bits (710), Expect = 3e-77
Identities = 169/540 (31%), Positives = 230/540 (42%), Gaps = 38/540 (7%)
Query: 165 CQPNYYNTTCTTFCRP-RDDKFGHYSCTP--DGDK-HCLPGWQGDNCE--KPVCKEGCHP 218
C Y++ TC + + H +C +G K C PGW G NC+ C+
Sbjct: 704 CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
Query: 219 THGRC-DRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYC--NGSSWDCTCDTNWGG 269
G C D C CR G+ G C ++C P G C + + + C C + G
Sbjct: 764 NGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTG 823
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYF-CRC-AEGFSGVDCERVDNPCAPQPCAHG 327
C+ L C PC++GG C + + F C C G G CE N C PC HG
Sbjct: 824 ATCEVVLAPCAP-SPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHG 882
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
S T + C C G+ G PC +G SC D ++ C+C G+ G
Sbjct: 883 A-SCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGT 941
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQC 446
C ED++EC A PC N A C + Y+C C AG++G CE N DCT C
Sbjct: 942 FCEEDINEC--------ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 993
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC+D ++ F C C G+ G C V++C RPC GG C D +RC CP G++
Sbjct: 994 FNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYT 1053
Query: 507 GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
G NC++ C SPC NG C+ + Y C C GWTG C + +C V +
Sbjct: 1054 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV----SCEVAAQRQ 1109
Query: 567 ERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSA 626
+C +GG CV + G+ S Q G TC
Sbjct: 1110 GVDVARLCQHGGLCV-DAGN---THHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL 1165
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
G++C C G G C +D C S PC+NGG C+ + C C G G C + V
Sbjct: 1166 --GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINV 1223
Score = 280 bits (687), Expect = 2e-74
Identities = 162/521 (31%), Positives = 232/521 (44%), Gaps = 53/521 (10%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCS----QCQPYPG 248
CL G+ G CE V C C D+ G+ C C PG+ G C +C P
Sbjct: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPC 499
Query: 249 CKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
+G C + + C C T + G LC D++ C + PC++G C + P+ Y C C EG
Sbjct: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLD-GPNTYTCVCTEG 557
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
++G CE + C P PC +G+C T FTC C G+ G +S PC
Sbjct: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRLR 615
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+C+D + + C C G TGP C ++D+C A PC ++ C + GY CAC
Sbjct: 616 GTCQDPDNAYLCFCLKGTTGPNCEINLDDC--------ASSPC-DSGTCLDKIDGYECAC 666
Query: 427 LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
G+TG C +N+D+C G C +G TC D ++ F C C GY TC +V++C PC
Sbjct: 667 EPGYTGSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
+G C D LN Y+C C G+SGTNC+ + + C +PC NG C S C C G++G
Sbjct: 727 HGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSG 785
Query: 546 KN-------CTQRAARDRKTC---------SVLVEESER--------CAEGMCANGGTCV 581
N C ++ TC + L+ + CA C NGG C
Sbjct: 786 PNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC- 844
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG 641
R+ + + G +C + + C C+ G +G
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTH--GXYRCHCQAGYSG 902
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CE +D C +PC NGG C G C+C+ G+ G C
Sbjct: 903 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFC 943
Score = 277 bits (678), Expect = 2e-73
Identities = 159/506 (31%), Positives = 223/506 (44%), Gaps = 49/506 (9%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG--DCDCRPGWRGELC----SQCQPY 246
C G+ G C + V C G +P G+C + G +C C G+ G C ++C
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 247 PGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P C + C C + G+ C+ + + C + PC H G C + +++ C C
Sbjct: 460 PCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECAS-SPCLHNGRCLDKI-NEFQCECP 517
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF+G C+ + CA PC +G L G +TC C G+ G PC
Sbjct: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTCVCTEGYTGTHCEVDIDECDPDPCH 576
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC+D + FTC C G+TG C +++ECS + PC C + Y C
Sbjct: 577 YG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQ--------PCRLRGTCQDPDNAYLC 627
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
CL G TG +CE N+DDC TC+D +D + CAC GY G C+ ++D+CA PC
Sbjct: 628 FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPC 687
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C D +N + C CP G+ C + + C +PC +G AC + + Y C C PGW+
Sbjct: 688 HNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKCDCDPGWS 746
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G NC + +E C C NGGTC
Sbjct: 747 GTNCD-------------INNNE-CESNPCVNGGTC----KDMTSGIVCTCREGFSGPNC 788
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
GTC+ G+ C C TGA CE+ L C SPCRNGG C
Sbjct: 789 QTNINECASNPCLNKGTCIDDV--AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
Query: 665 GSGW--WMCEC-VAGWTGETCAVRVS 687
+ + C C AG G+TC V ++
Sbjct: 847 SEDYESFSCVCPTAGAKGQTCEVDIN 872
Score = 274 bits (671), Expect = 1e-72
Identities = 169/515 (32%), Positives = 223/515 (43%), Gaps = 54/515 (10%)
Query: 197 HCLPGWQGDNCEKPV--CKEG-CHPTHGRCD---RPGDCDCRPGWRGELC----SQCQPY 246
HC G+ G NCE + C+ CH G C CDC PG+RG C ++C
Sbjct: 895 HCQAGYSGRNCETDIDDCRPNPCH-NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 953
Query: 247 PGCKHGY-CNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P C++G C S+ CTC + GI C+ + C T C +GGTC + + + C C
Sbjct: 954 P-CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGI-NSFTCLC 1010
Query: 304 AEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGF-TCTCDRGWGGXXXXXXXXXXASG 361
GF+G C+ V N C +PC GTC RG CTC +G+ G S
Sbjct: 1011 PPGFTGSYCQHVVNECDSRPCLLGGTCQ---DGRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTA 419
PC +G C + CEC GWTG C C + +G C + C +
Sbjct: 1068 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1127
Query: 420 GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
+ C C AG+TG CE VD+C+ C +GATC D + + C C AGY G CS ++D+
Sbjct: 1128 NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE 1187
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-------AGSP-CGNGAACYT 530
C PC NGG C+DL N Y+C CP G G +CE + D C + SP C N C
Sbjct: 1188 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVD 1247
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT--CVREEGSWR 588
Y C C PG+ G+ C + C C GT CV+ +
Sbjct: 1248 QVGGYSCTCPPGFVGERCEG--------------DVNECLSNPCDARGTQNCVQRVNDFH 1293
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-LPSALPPGWACGCREGRTGALCELS 647
+S + GGTC + S G+ C C G GA CE
Sbjct: 1294 CECRAGHTGRRCESVINGCKGKPC----KNGGTCAVASNTARGFICKCPAGFEGATCEND 1349
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CGS C NGG C+ G C C+ +TG C
Sbjct: 1350 ARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1384
Score = 273 bits (669), Expect = 2e-72
Identities = 158/500 (31%), Positives = 206/500 (41%), Gaps = 47/500 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQPYPGCKHGYCNG-- 256
+ C C+ G C THG C C+ G+ G C C+P P G C
Sbjct: 872 NECVLSPCRHGASCQNTHGXYR----CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGI 927
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
++ C C + G C++D+N C + +PC++G C + D Y C C GFSG+ CE
Sbjct: 928 NTAFCDCLPGFRGTFCEEDINECAS-DPCRNGANCTDCV-DSYTCTCPAGFSGIHCENNT 985
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C C +G + G FTC C G+ G S PCL G +C+D
Sbjct: 986 PDCTESSCFNGGTCVDGIN-SFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLH 1044
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TGP C V C PC N C T Y C C +GWTG C+
Sbjct: 1045 RCTCPQGYTGPNCQNLVHWCDS--------SPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1096
Query: 437 TNVDDC-----------TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C C HG C+D + HC C AGY G C VD+C+P PC
Sbjct: 1097 VPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQ 1156
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
NG C D L Y C C G+ G NC ++ D C PC NG C + Y C C G G
Sbjct: 1157 NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQG 1216
Query: 546 KNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXX 605
+C C+ V+ R + C N GTCV + G + +
Sbjct: 1217 VHCEINV----DDCNPPVDPVSRSPK--CFNNGTCVDQVGGYSCTCPPGFVGERCEG--- 1267
Query: 606 XXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG 665
A GT + C CR G TG CE ++ C PC+NGG C
Sbjct: 1268 -DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVA 1326
Query: 666 SG---WWMCECVAGWTGETC 682
S ++C+C AG+ G TC
Sbjct: 1327 SNTARGFICKCPAGFEGATC 1346
Score = 249 bits (609), Expect = 4e-65
Identities = 145/500 (29%), Positives = 216/500 (43%), Gaps = 48/500 (9%)
Query: 203 QGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCSQCQPYPG--CKH-GYCNG 256
+G C +P E C G+C+ C C + G C P CK+ G C+
Sbjct: 20 RGPRCSQP--GETCL-NGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 257 ------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
+ + C+C + G LC L+ PC++GGTC+ +Y CRC G+SG
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 311 DCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP--CLHGAS 368
C++ D PCA PCA+G L + C C + G P C HG +
Sbjct: 137 SCQQAD-PCASNPCANGGQCLPFEA-SYICHCPPSFHGPTCRQDVNECGQKPRLCRHGGT 194
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACL 427
C + + + C C TGP C CS PC N C T + CACL
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSP--------SPCQNGGTCRPTGDVTHECACL 246
Query: 428 AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPC 484
G+TG++CE N+DDC G C +G C+D V+ ++C C + G+ C+ DVD+C P C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
NGG C + Y C+C G++G +C ++ D CA + C +GA C+ + +YC C G T
Sbjct: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G +L ++ C C G C + +
Sbjct: 367 G---------------LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
+ G C+ + + C C +G TG CE+ ++ C S+PC+N C+
Sbjct: 412 DVDECSLGANPCEHAGKCINTL--GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 665 GSGWWMCECVAGWTGETCAV 684
G + C C+ G+ G C V
Sbjct: 470 QIGEFQCMCMPGYEGVHCEV 489
Score = 248 bits (608), Expect = 6e-65
Identities = 145/509 (28%), Positives = 213/509 (41%), Gaps = 51/509 (10%)
Query: 198 CLPGWQGDNCEK--PVCKEGCHPTHGRC---DRPGDCDCRPGWRGELCSQ----CQPYPG 248
C PGW G +C++ P C G+C + C C P + G C Q C P
Sbjct: 129 CPPGWSGKSCQQADPCASNPC-ANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPR 187
Query: 249 -CKH-GYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H G C+ S+ C C G C++ C + PCQ+GGTC T + C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-SPSPCQNGGTCRPTGDVTHECACL 246
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
GF+G +CE + C C +G + G + C C W G P
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCPCPPEWTGQYCTEDVDECQLMPNA 305
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C + G+ C C +GWTG C+E++D+C A C + A C++ +
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC--------ASAACFHGATCHDRVASF 357
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATC--IDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G TG C N + C G+ C + C C +GY G CS DVD+C+
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
PC + G+C++ L ++ C C G++G CE D + C +PC N A C ++ C
Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCM 477
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
C PG+ G +C ++ CA C + G C+ + ++
Sbjct: 478 CMPGYEGVHCE--------------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH 523
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRN 658
+ G CL P + C C EG TG CE+ +D C PC
Sbjct: 524 LCQ----YDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHY 577
Query: 659 GGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G C G + C C G+TG C ++
Sbjct: 578 GS-CKDGVATFTCLCRPGYTGHHCETNIN 605
Score = 226 bits (552), Expect = 3e-58
Identities = 162/552 (29%), Positives = 223/552 (40%), Gaps = 89/552 (16%)
Query: 165 CQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDK----HCLPGWQGDNCEKPV------ 211
CQ Y C T CRP G SCT DG CLPG++G CE+ +
Sbjct: 896 CQAGYSGRNCETDIDDCRPNPCHNGG-SCT-DGINTAFCDCLPGFRGTFCEEDINECASD 953
Query: 212 -CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYC-NG-------SSWDCT 262
C+ G + T C C C G+ G C P C C NG +S+ C
Sbjct: 954 PCRNGANCTD--CVDSYTCTCPAGFSGIHCENNTP--DCTESSCFNGGTCVDGINSFTCL 1009
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C +N C + PC GGTC++ + C C +G++G +C+ + + C
Sbjct: 1010 CPPGFTGSYCQHVVNECDSR-PCLLGGTCQD-GRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXX----------XXXXXXXXASGPCLHGASCRDH 372
PC +G T+ + C C GW G + C HG C D
Sbjct: 1068 PCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1126
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ C C G+TG C + VDECS PC N A C + GGYSC C+AG+ G
Sbjct: 1127 GNTHHCRCQAGYTGSYCEDLVDECSP--------SPCQNGATCTDYLGGYSCKCVAGYHG 1178
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR--------P 483
+C +D+C C +G TC+DL + + C+C G G C ++VDDC P
Sbjct: 1179 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK 1238
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-GNGAA-CYTAQSDYYCHCAP 541
C N G CVD + Y C CP GF G CE D + C +PC G C +D++C C
Sbjct: 1239 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1298
Query: 542 GWTGKNCTQ-------RAARDRKTCSVLVEESE----RCAEGM----------------C 574
G TG+ C + ++ TC+V + +C G C
Sbjct: 1299 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1358
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
NGGTC+ G + GTC P++ P + C
Sbjct: 1359 LNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCL 1416
Query: 635 CREGRTGALCEL 646
C G LC +
Sbjct: 1417 CPAKFNGLLCHI 1428
Score = 175 bits (426), Expect = 6e-43
Identities = 127/433 (29%), Positives = 176/433 (40%), Gaps = 63/433 (14%)
Query: 164 LCQPNYYNTTC---TTFCRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPV------ 211
LC P + + C C R G +C H C G+ G NC+ V
Sbjct: 1009 LCPPGFTGSYCQHVVNECDSRPCLLGG-TCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSS 1067
Query: 212 -CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQPYPG---------CKHG-YC 254
CK G C TH + C+C GW G C C+ C+HG C
Sbjct: 1068 PCKNGGKCWQTHTQYR----CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1123
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
G++ C C + G C+ ++ C PCQ+G TC + Y C+C G+ GV+C
Sbjct: 1124 VDAGNTHHCRCQAGYTGSYCEDLVDECSP-SPCQNGATCTDYLGG-YSCKCVAGYHGVNC 1181
Query: 313 ERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX--------XASGPC 363
+ C PC +G TC T + C+C RG G S C
Sbjct: 1182 SEEIDECLSHPCQNGGTCLDLPNT--YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1239
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
+ +C D + G++C C G+ G C DV+EC CV +
Sbjct: 1240 FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRV------NDFH 1293
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCI---DLVDDFHCACAAGYAGRTCSLDVDDC 479
C C AG TGR CE+ ++ C G+ C +G TC + F C C AG+ G TC D C
Sbjct: 1294 CECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC 1353
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHC-AGSPCGNGAACY-TAQSDYY 536
C NGG C+ + C+C F+G C+ C G+PC N C T++S +Y
Sbjct: 1354 GSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFY 1413
Query: 537 -CHCAPGWTGKNC 548
C C + G C
Sbjct: 1414 RCLCPAKFNGLLC 1426
Score = 101 bits (243), Expect = 1e-20
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 41/336 (12%)
Query: 205 DNCEKPVCKEGCHP---THGRC-DRPG--DCDCRPGWRGELC----SQCQPYPGCKHGYC 254
D+C PV P +G C D+ G C C PG+ GE C ++C P G
Sbjct: 1224 DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQ 1283
Query: 255 NG----SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAPDQYFCRCAEGF 307
N + + C C G C+ +N C +PC++GGTC NTA + C+C GF
Sbjct: 1284 NCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPCKNGGTCAVASNTARG-FICKCPAGF 1341
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--PCLH 365
G CE C C +G ++G R TC C + G G PC +
Sbjct: 1342 EGATCENDARTCGSLRCLNGGTCISGP-RSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 1400
Query: 366 GASCRDHLDG--FTCECADGWTGPACA---EDVDECSGRSMTEGALGPCVNAAACNNTAG 420
+C + + C C + G C +GR + + C AG
Sbjct: 1401 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1460
Query: 421 GYSCA--C---LAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C+ C GW G DC N +D C C D HC AG C D
Sbjct: 1461 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG--CLFD 1518
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
DC G+C L + Y C FS +C+
Sbjct: 1519 GFDCQRAE----GQCNPLYDQY---CKDHFSDGHCD 1547
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 295 bits (723), Expect = 7e-79
Identities = 174/551 (31%), Positives = 244/551 (44%), Gaps = 70/551 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGK-------NCTQRAARDRKTC---------SVLVEESER- 568
C + + C C G+TG C+ + TC S + + +
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN 1059
Query: 569 -------CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXX 615
C+ C N GTCV+++ + D
Sbjct: 1060 CQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
Query: 616 XQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
Q G C+ + C C G TG+ CE LD C S+PC++G C G + CECV
Sbjct: 1120 CQHSGVCINAGNTH--YCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVP 1177
Query: 676 GWTGETCAVRV 686
G+ G C V
Sbjct: 1178 GYQGVNCEYEV 1188
Score = 292 bits (716), Expect = 5e-78
Identities = 169/541 (31%), Positives = 242/541 (44%), Gaps = 58/541 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGCHP 218
LC+ N N C P D H C D + C PG+ G C + C
Sbjct: 566 LCEENIDN------CDP--DPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
Query: 219 THGRC-DRPG--DCDCRPGWRGELCS----QCQPYPGCKHGYC-NG-SSWDCTCDTNWGG 269
GRC D C+C+PG G C C P C HG C +G + + C C + G
Sbjct: 618 NDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP-CIHGICMDGINRYSCVCSPGFTG 676
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTC 329
C+ D++ C ++ PC+ G TC N + + C C EG C N C PC HG C
Sbjct: 677 QRCNIDIDECASN-PCRKGATCINGV-NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNC 734
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
+ G G+ C CD GW G S PC +G +C + ++G+ C C G+ G C
Sbjct: 735 T--GGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLH 448
++DEC A PC+N C + GY+C C+ +TG++C+T + C+ C +
Sbjct: 793 QVNIDEC--------ASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCEN 844
Query: 449 GATCIDL--VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
A C + + + C CA G+ G+ C++D+D+C +PC N G C + +Y C CP GFS
Sbjct: 845 AAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
Query: 507 GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
G +CE+D D C +PC NG +C + + C C PG+TG +
Sbjct: 905 GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQT--------------DM 950
Query: 567 ERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSA 626
C C NGGTC S+ ++ GGTC+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFN----GGTCVDGI 1006
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
++C C G TG+ C ++ C S PC N G CV G G + C C G+TG+ C V
Sbjct: 1007 --NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 687 S 687
+
Sbjct: 1065 N 1065
Score = 283 bits (693), Expect = 3e-75
Identities = 164/510 (32%), Positives = 239/510 (46%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
C G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 278 bits (682), Expect = 6e-74
Identities = 161/512 (31%), Positives = 233/512 (45%), Gaps = 54/512 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
D C ++PC+NGG C+ G + C C+ G+TG+
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGD 944
Score = 277 bits (680), Expect = 1e-73
Identities = 151/496 (30%), Positives = 218/496 (43%), Gaps = 35/496 (7%)
Query: 198 CLPGWQGDNCE--KPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C GW G NCE K C G CD + C C+ G++G C +C P
Sbjct: 745 CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC 804
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP-DQYFCRCAE 305
G C + S + C C + G C L C + PC++ C+ + + Y C CA
Sbjct: 805 LNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN-PCENAAVCKESPNFESYTCLCAP 863
Query: 306 GFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
G+ G C + C +PC HG C T + C C G+ G + PC
Sbjct: 864 GWQGQRCTIDIDECISKPCMNHGLCH--NTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
+G SC D ++ F+C C G+TG D++EC ++E PC N C++ Y+C
Sbjct: 922 NGGSCMDGVNTFSCLCLPGFTGDKYQTDMNEC----LSE----PCKNGGTCSDYVNSYTC 973
Query: 425 ACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C AG+ G CE N+++CT C +G TC+D ++ F C C G+ G C ++++C+ P
Sbjct: 974 KCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHP 1033
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G CVD L YRC CP+G++G NC+ + C+ SPC N C +++ C C GW
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G C +C + E +C + G C+ + S
Sbjct: 1094 AGAYCDV----PNVSCDIAASRRGVLVEHLCQHSGVCINAGNT----HYCQCPLGYTGSY 1145
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q G TC S G+ C C G G CE +D C + PC+NGG C+
Sbjct: 1146 CEEQLDECASNPCQHGATC--SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCI 1203
Query: 664 GGSGWWMCECVAGWTG 679
+ C C G G
Sbjct: 1204 DLVNHFKCSCPPGTRG 1219
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 254 bits (621), Expect = 2e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 237 bits (581), Expect = 1e-61
Identities = 127/410 (30%), Positives = 195/410 (47%), Gaps = 51/410 (12%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G + N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKYQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
Y C C PG+ G NC E + C C NGGTC+
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCI 1203
Score = 223 bits (546), Expect = 2e-57
Identities = 132/403 (32%), Positives = 173/403 (42%), Gaps = 42/403 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
G+ G NCE + D C PC NG C + + C C PG G
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
Score = 222 bits (542), Expect = 6e-57
Identities = 142/491 (28%), Positives = 207/491 (42%), Gaps = 61/491 (12%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSL 648
G G LS+
Sbjct: 1216 GTRGMKSSLSI 1226
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Score = 33.9 bits (74), Expect = 2.9
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 11/71 (15%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRG 237
D G Y C C+PG+QG NCE V C+ G C D C C PG RG
Sbjct: 1166 DFIGGYRC------ECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
Query: 238 ELCSQCQPYPG 248
S +PG
Sbjct: 1220 MKSSLSIFHPG 1230
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 293 bits (720), Expect = 2e-78
Identities = 164/503 (32%), Positives = 221/503 (43%), Gaps = 46/503 (9%)
Query: 198 CLPGWQGDNCEKPV--CK-EGCHPTHGRCDRPGD--CDCRPGWRGELC---SQCQPYPGC 249
C+ GW GD+C + + C C P DR C C G G LC C P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCH 385
Query: 250 KHGYCN----GSSWDCTCDTNWGGILCDQDLNYCG--THEPCQHGGTCENTAPDQYFCRC 303
K C+ + CTC + G C +D++ C PC+H G C NT + C C
Sbjct: 386 KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
+G++G CE N C PC + L GFTC C G+ G S PC
Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
++ C D ++ F C C G+TGP C D+D+CS PC+N A C + GY
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--------PCLNGAKCIDHPNGYE 555
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+TG CE N+D+C H C D +D + C C GY G CS +D+C P
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G C+DL+N Y+C C G SG NCE + D CA +PC +G C + Y C C+PG+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGF 674
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
TG+ C ++ ++E CA C G TC+ +R S
Sbjct: 675 TGQRC-----------NIDIDE---CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GG G+ C C G G CE+ + C S+PC+NGG C
Sbjct: 721 VNECLSNPCIHGNCTGGLS-------GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 664 GGSGWWMCECVAGWTGETCAVRV 686
+ C C G+ G C V +
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVNI 796
Score = 289 bits (708), Expect = 4e-77
Identities = 168/527 (31%), Positives = 235/527 (44%), Gaps = 68/527 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G C D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + C C G+TG C + E C+ C N GTCV G
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFC--------------LHEINECSSHPCLNEGTCVDGLG 1045
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
++R + + GTC+ C C G GA C+
Sbjct: 1046 TYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTCVQKKAES--QCLCPSGWAGAYCD 1099
Query: 646 ---LSLDLCGSSP-------CRNGGRCVGGSGWWMCECVAGWTGETC 682
+S D+ S C++ G C+ C+C G+TG C
Sbjct: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Score = 283 bits (693), Expect = 3e-75
Identities = 164/510 (32%), Positives = 239/510 (46%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
C G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 281 bits (690), Expect = 7e-75
Identities = 162/514 (31%), Positives = 234/514 (45%), Gaps = 54/514 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C ++PC+NGG C+ G + C C+ G+TG+ C
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 262 bits (642), Expect = 4e-69
Identities = 149/513 (29%), Positives = 233/513 (45%), Gaps = 58/513 (11%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G C+ N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Y C C PG+ G NC E + C C NGGTC+ ++
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ GG C+ G++C C G G CE ++ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLN---GGQCMDRI--GGYSCRCLPGFAGERCEGDINEC 1268
Query: 652 GSSPCRNGGR--CVGGSGWWMCECVAGWTGETC 682
S+PC + G C+ + ++C C + +TG C
Sbjct: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Score = 260 bits (638), Expect = 1e-68
Identities = 158/526 (30%), Positives = 229/526 (43%), Gaps = 62/526 (11%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSLDLCGSSP-CRNGGRCVGGSGWWMCECVAGWTGETC 682
G G LCE ++D C P C NGG+C+ G + C C+ G+ GE C
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Score = 260 bits (638), Expect = 1e-68
Identities = 167/544 (30%), Positives = 221/544 (40%), Gaps = 64/544 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G C
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G+ G NCE + D C PC NG C + + C C PG G C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE------------- 1223
Query: 563 VEESERCAEG-MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
E + CA G C NGG C+ G + + +
Sbjct: 1224 -ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLD 1280
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW---WMCECVAGWT 678
C+ L + C CR TG CE +D+C PC NGG C S ++C C G++
Sbjct: 1281 CI--QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 679 GETC 682
G C
Sbjct: 1339 GARC 1342
Score = 255 bits (624), Expect = 7e-67
Identities = 149/518 (28%), Positives = 223/518 (43%), Gaps = 57/518 (11%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPV---CKEGCHPTH--GRC---DRPGDCDCRPGWRG 237
G Y CT C G++G +C + V +P G+C D C+C G+ G
Sbjct: 397 GQYICT------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C + C C + G+ C+ ++N C ++ PC + G C
Sbjct: 451 PRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQC 509
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXX 351
+ +++ C C GF+G C+ + C+ PC +G + G+ C C G+ G
Sbjct: 510 VDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYECQCATGFTGVLC 567
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
PC HG C+D +D +TC C G+ G C++ +DEC PC+N
Sbjct: 568 EENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYS--------SPCLN 618
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
C + GY C C G +G +CE N DDC C+HG C+D ++ + C C+ G+ G+
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQ 677
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C++D+D+CA PC G C++ +N +RCICP G +C + C +PC +G C
Sbjct: 678 RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTG 736
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
S Y C C GW G NC V+++E C C NGGTC +R
Sbjct: 737 GLSGYKCLCDAGWVGINCE-------------VDKNE-CLSNPCQNGGTCDNLVNGYRCT 782
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
GTC G+ C C TG C+ L
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQ----GTCFDDI--SGYTCHCVLPYTGKNCQTVLAP 836
Query: 651 CGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRV 686
C +PC N C + + C C GW G+ C + +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Score = 254 bits (621), Expect = 2e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 251 bits (614), Expect = 1e-65
Identities = 187/671 (27%), Positives = 263/671 (39%), Gaps = 67/671 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDK--FGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGC 216
LC P + CT K H C + C PG+ G +CE+ + C
Sbjct: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 217 HPTHGRCD---RPGDCDCRPGWRGELC----SQCQPYPGCKHG-YCNG--SSWDCTCDTN 266
G C C C PG+ G+ C ++C P CK+G C+ +S+ C C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQAG 978
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G+ C+ ++N C T C +GGTC + + + C C GF+G C N C+ PC +
Sbjct: 979 FDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 327 -GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
GTC GT R C+C G+ G + PC + +C C C GW
Sbjct: 1037 EGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 385 TGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G C C + G L C ++ C N + C C G+TG CE +D+C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 443 TGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C HGATC D + + C C GY G C +VD+C +PC NGG C+DL+N ++C C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 502 PVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
P G G CE++ D CA P C NG C Y C C PG+ G+ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE----------- 1262
Query: 561 VLVEESERCAEGMCANGGT--CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
+ C C++ G+ C++ + ++
Sbjct: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET---FVDVCPQMPCLNG 1316
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G + S +P G+ C C G +GA C+ S CG CR G +CV + C C +
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 679 GET-CAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRC-LCPAPPQRAARRCLETVAGLE 736
E+ CA S +RC L APP CL +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 737 AEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNA---CWCSGGVPTCTRL 793
A D N +H DG G C + W C++ CW C L
Sbjct: 1434 ARDGVCDEACN-SHACQ-------WDG-GDCSLTMENPWANCSSPLPCWDYIN-NQCDEL 1483
Query: 794 WCGLPDCLAPN 804
C +CL N
Sbjct: 1484 -CNTVECLFDN 1493
Score = 97.1 bits (231), Expect = 3e-19
Identities = 95/360 (26%), Positives = 136/360 (37%), Gaps = 52/360 (14%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPG--DCDCRPGWR 236
D H+ C+ C PG +G CE+ + C G H +G +C DR G C C PG+
Sbjct: 1204 DLVNHFKCS------CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 237 GELC----SQCQPYPGCKHGYCN----GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
GE C ++C P G + + + C C + + G C+ ++ C PC +G
Sbjct: 1258 GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-PQMPCLNG 1316
Query: 289 GTCE--NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
GTC + PD + CRC GFSG C+ + C C G T G C C
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGE-QCVHTASGPRCFCP--- 1369
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEG 404
AS PC HG SC ++C+CA ++G C S T
Sbjct: 1370 ---SPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT-- 1424
Query: 405 ALGP-CVNAA---ACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFH 460
L C + A C+ ++C W G DC +++ C C D +++
Sbjct: 1425 CLSQYCADKARDGVCDEACNSHACQ----WDGGDCSLTMENPWANCSSPLPCWDYINN-- 1478
Query: 461 CACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C C D +C + C C D C G + C D CA
Sbjct: 1479 -QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNH--CDQGCNSEECGWDGLDCA 1535
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 293 bits (720), Expect = 2e-78
Identities = 164/503 (32%), Positives = 221/503 (43%), Gaps = 46/503 (9%)
Query: 198 CLPGWQGDNCEKPV--CK-EGCHPTHGRCDRPGD--CDCRPGWRGELC---SQCQPYPGC 249
C+ GW GD+C + + C C P DR C C G G LC C P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCH 385
Query: 250 KHGYCN----GSSWDCTCDTNWGGILCDQDLNYCG--THEPCQHGGTCENTAPDQYFCRC 303
K C+ + CTC + G C +D++ C PC+H G C NT + C C
Sbjct: 386 KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
+G++G CE N C PC + L GFTC C G+ G S PC
Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
++ C D ++ F C C G+TGP C D+D+CS PC+N A C + GY
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--------PCLNGAKCIDHPNGYE 555
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+TG CE N+D+C H C D +D + C C GY G CS +D+C P
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G C+DL+N Y+C C G SG NCE + D CA +PC +G C + Y C C+PG+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGF 674
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
TG+ C ++ ++E CA C G TC+ +R S
Sbjct: 675 TGQRC-----------NIDIDE---CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GG G+ C C G G CE+ + C S+PC+NGG C
Sbjct: 721 VNECLSNPCIHGNCTGGLS-------GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 664 GGSGWWMCECVAGWTGETCAVRV 686
+ C C G+ G C V +
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVNI 796
Score = 289 bits (708), Expect = 4e-77
Identities = 168/527 (31%), Positives = 235/527 (44%), Gaps = 68/527 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G C D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + C C G+TG C + E C+ C N GTCV G
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFC--------------LHEINECSSHPCLNEGTCVDGLG 1045
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
++R + + GTC+ C C G GA C+
Sbjct: 1046 TYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTCVQKKAES--QCLCPSGWAGAYCD 1099
Query: 646 ---LSLDLCGSSP-------CRNGGRCVGGSGWWMCECVAGWTGETC 682
+S D+ S C++ G C+ C+C G+TG C
Sbjct: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Score = 283 bits (693), Expect = 3e-75
Identities = 164/510 (32%), Positives = 239/510 (46%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
C G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 281 bits (690), Expect = 7e-75
Identities = 162/514 (31%), Positives = 234/514 (45%), Gaps = 54/514 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C ++PC+NGG C+ G + C C+ G+TG+ C
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 262 bits (642), Expect = 4e-69
Identities = 149/513 (29%), Positives = 233/513 (45%), Gaps = 58/513 (11%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G C+ N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Y C C PG+ G NC E + C C NGGTC+ ++
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ GG C+ G++C C G G CE ++ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLN---GGQCMDRI--GGYSCRCLPGFAGERCEGDINEC 1268
Query: 652 GSSPCRNGGR--CVGGSGWWMCECVAGWTGETC 682
S+PC + G C+ + ++C C + +TG C
Sbjct: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Score = 260 bits (638), Expect = 1e-68
Identities = 158/526 (30%), Positives = 229/526 (43%), Gaps = 62/526 (11%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSLDLCGSSP-CRNGGRCVGGSGWWMCECVAGWTGETC 682
G G LCE ++D C P C NGG+C+ G + C C+ G+ GE C
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Score = 260 bits (638), Expect = 1e-68
Identities = 167/544 (30%), Positives = 221/544 (40%), Gaps = 64/544 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G C
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G+ G NCE + D C PC NG C + + C C PG G C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE------------- 1223
Query: 563 VEESERCAEG-MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
E + CA G C NGG C+ G + + +
Sbjct: 1224 -ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLD 1280
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW---WMCECVAGWT 678
C+ L + C CR TG CE +D+C PC NGG C S ++C C G++
Sbjct: 1281 CI--QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 679 GETC 682
G C
Sbjct: 1339 GARC 1342
Score = 255 bits (624), Expect = 7e-67
Identities = 149/518 (28%), Positives = 223/518 (43%), Gaps = 57/518 (11%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPV---CKEGCHPTH--GRC---DRPGDCDCRPGWRG 237
G Y CT C G++G +C + V +P G+C D C+C G+ G
Sbjct: 397 GQYICT------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C + C C + G+ C+ ++N C ++ PC + G C
Sbjct: 451 PRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQC 509
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXX 351
+ +++ C C GF+G C+ + C+ PC +G + G+ C C G+ G
Sbjct: 510 VDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYECQCATGFTGVLC 567
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
PC HG C+D +D +TC C G+ G C++ +DEC PC+N
Sbjct: 568 EENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYS--------SPCLN 618
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
C + GY C C G +G +CE N DDC C+HG C+D ++ + C C+ G+ G+
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQ 677
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C++D+D+CA PC G C++ +N +RCICP G +C + C +PC +G C
Sbjct: 678 RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTG 736
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
S Y C C GW G NC V+++E C C NGGTC +R
Sbjct: 737 GLSGYKCLCDAGWVGINCE-------------VDKNE-CLSNPCQNGGTCDNLVNGYRCT 782
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
GTC G+ C C TG C+ L
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQ----GTCFDDI--SGYTCHCVLPYTGKNCQTVLAP 836
Query: 651 CGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRV 686
C +PC N C + + C C GW G+ C + +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Score = 254 bits (621), Expect = 2e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 251 bits (614), Expect = 1e-65
Identities = 187/671 (27%), Positives = 263/671 (39%), Gaps = 67/671 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDK--FGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGC 216
LC P + CT K H C + C PG+ G +CE+ + C
Sbjct: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 217 HPTHGRCD---RPGDCDCRPGWRGELC----SQCQPYPGCKHG-YCNG--SSWDCTCDTN 266
G C C C PG+ G+ C ++C P CK+G C+ +S+ C C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQAG 978
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G+ C+ ++N C T C +GGTC + + + C C GF+G C N C+ PC +
Sbjct: 979 FDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 327 -GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
GTC GT R C+C G+ G + PC + +C C C GW
Sbjct: 1037 EGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 385 TGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G C C + G L C ++ C N + C C G+TG CE +D+C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 443 TGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C HGATC D + + C C GY G C +VD+C +PC NGG C+DL+N ++C C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 502 PVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
P G G CE++ D CA P C NG C Y C C PG+ G+ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE----------- 1262
Query: 561 VLVEESERCAEGMCANGGT--CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
+ C C++ G+ C++ + ++
Sbjct: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET---FVDVCPQMPCLNG 1316
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G + S +P G+ C C G +GA C+ S CG CR G +CV + C C +
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 679 GET-CAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRC-LCPAPPQRAARRCLETVAGLE 736
E+ CA S +RC L APP CL +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 737 AEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNA---CWCSGGVPTCTRL 793
A D N +H DG G C + W C++ CW C L
Sbjct: 1434 ARDGVCDEACN-SHACQ-------WDG-GDCSLTMENPWANCSSPLPCWDYIN-NQCDEL 1483
Query: 794 WCGLPDCLAPN 804
C +CL N
Sbjct: 1484 -CNTVECLFDN 1493
Score = 97.1 bits (231), Expect = 3e-19
Identities = 95/360 (26%), Positives = 136/360 (37%), Gaps = 52/360 (14%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPG--DCDCRPGWR 236
D H+ C+ C PG +G CE+ + C G H +G +C DR G C C PG+
Sbjct: 1204 DLVNHFKCS------CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 237 GELC----SQCQPYPGCKHGYCN----GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
GE C ++C P G + + + C C + + G C+ ++ C PC +G
Sbjct: 1258 GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-PQMPCLNG 1316
Query: 289 GTCE--NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
GTC + PD + CRC GFSG C+ + C C G T G C C
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGE-QCVHTASGPRCFCP--- 1369
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEG 404
AS PC HG SC ++C+CA ++G C S T
Sbjct: 1370 ---SPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT-- 1424
Query: 405 ALGP-CVNAA---ACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFH 460
L C + A C+ ++C W G DC +++ C C D +++
Sbjct: 1425 CLSQYCADKARDGVCDEACNSHACQ----WDGGDCSLTMENPWANCSSPLPCWDYINN-- 1478
Query: 461 CACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C C D +C + C C D C G + C D CA
Sbjct: 1479 -QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNH--CDQGCNSEECGWDGLDCA 1535
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 293 bits (720), Expect = 2e-78
Identities = 164/503 (32%), Positives = 221/503 (43%), Gaps = 46/503 (9%)
Query: 198 CLPGWQGDNCEKPV--CK-EGCHPTHGRCDRPGD--CDCRPGWRGELC---SQCQPYPGC 249
C+ GW GD+C + + C C P DR C C G G LC C P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCH 385
Query: 250 KHGYCN----GSSWDCTCDTNWGGILCDQDLNYCG--THEPCQHGGTCENTAPDQYFCRC 303
K C+ + CTC + G C +D++ C PC+H G C NT + C C
Sbjct: 386 KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
+G++G CE N C PC + L GFTC C G+ G S PC
Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
++ C D ++ F C C G+TGP C D+D+CS PC+N A C + GY
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--------PCLNGAKCIDHPNGYE 555
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+TG CE N+D+C H C D +D + C C GY G CS +D+C P
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G C+DL+N Y+C C G SG NCE + D CA +PC +G C + Y C C+PG+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGF 674
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
TG+ C ++ ++E CA C G TC+ +R S
Sbjct: 675 TGQRC-----------NIDIDE---CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GG G+ C C G G CE+ + C S+PC+NGG C
Sbjct: 721 VNECLSNPCIHGNCTGGLS-------GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 664 GGSGWWMCECVAGWTGETCAVRV 686
+ C C G+ G C V +
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVNI 796
Score = 289 bits (708), Expect = 4e-77
Identities = 168/527 (31%), Positives = 235/527 (44%), Gaps = 68/527 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G C D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + C C G+TG C + E C+ C N GTCV G
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFC--------------LHEINECSSHPCLNEGTCVDGLG 1045
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
++R + + GTC+ C C G GA C+
Sbjct: 1046 TYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTCVQKKAES--QCLCPSGWAGAYCD 1099
Query: 646 ---LSLDLCGSSP-------CRNGGRCVGGSGWWMCECVAGWTGETC 682
+S D+ S C++ G C+ C+C G+TG C
Sbjct: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Score = 283 bits (693), Expect = 3e-75
Identities = 164/510 (32%), Positives = 239/510 (46%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
C G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 281 bits (690), Expect = 7e-75
Identities = 162/514 (31%), Positives = 234/514 (45%), Gaps = 54/514 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C ++PC+NGG C+ G + C C+ G+TG+ C
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 262 bits (642), Expect = 4e-69
Identities = 149/513 (29%), Positives = 233/513 (45%), Gaps = 58/513 (11%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G C+ N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Y C C PG+ G NC E + C C NGGTC+ ++
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ GG C+ G++C C G G CE ++ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLN---GGQCMDRI--GGYSCRCLPGFAGERCEGDINEC 1268
Query: 652 GSSPCRNGGR--CVGGSGWWMCECVAGWTGETC 682
S+PC + G C+ + ++C C + +TG C
Sbjct: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Score = 260 bits (638), Expect = 1e-68
Identities = 158/526 (30%), Positives = 229/526 (43%), Gaps = 62/526 (11%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSLDLCGSSP-CRNGGRCVGGSGWWMCECVAGWTGETC 682
G G LCE ++D C P C NGG+C+ G + C C+ G+ GE C
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Score = 260 bits (638), Expect = 1e-68
Identities = 167/544 (30%), Positives = 221/544 (40%), Gaps = 64/544 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G C
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G+ G NCE + D C PC NG C + + C C PG G C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE------------- 1223
Query: 563 VEESERCAEG-MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
E + CA G C NGG C+ G + + +
Sbjct: 1224 -ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLD 1280
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW---WMCECVAGWT 678
C+ L + C CR TG CE +D+C PC NGG C S ++C C G++
Sbjct: 1281 CI--QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 679 GETC 682
G C
Sbjct: 1339 GARC 1342
Score = 255 bits (624), Expect = 7e-67
Identities = 149/518 (28%), Positives = 223/518 (43%), Gaps = 57/518 (11%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPV---CKEGCHPTH--GRC---DRPGDCDCRPGWRG 237
G Y CT C G++G +C + V +P G+C D C+C G+ G
Sbjct: 397 GQYICT------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C + C C + G+ C+ ++N C ++ PC + G C
Sbjct: 451 PRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQC 509
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXX 351
+ +++ C C GF+G C+ + C+ PC +G + G+ C C G+ G
Sbjct: 510 VDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYECQCATGFTGVLC 567
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
PC HG C+D +D +TC C G+ G C++ +DEC PC+N
Sbjct: 568 EENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYS--------SPCLN 618
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
C + GY C C G +G +CE N DDC C+HG C+D ++ + C C+ G+ G+
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQ 677
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C++D+D+CA PC G C++ +N +RCICP G +C + C +PC +G C
Sbjct: 678 RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTG 736
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
S Y C C GW G NC V+++E C C NGGTC +R
Sbjct: 737 GLSGYKCLCDAGWVGINCE-------------VDKNE-CLSNPCQNGGTCDNLVNGYRCT 782
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
GTC G+ C C TG C+ L
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQ----GTCFDDI--SGYTCHCVLPYTGKNCQTVLAP 836
Query: 651 CGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRV 686
C +PC N C + + C C GW G+ C + +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Score = 254 bits (621), Expect = 2e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 251 bits (614), Expect = 1e-65
Identities = 187/671 (27%), Positives = 263/671 (39%), Gaps = 67/671 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDK--FGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGC 216
LC P + CT K H C + C PG+ G +CE+ + C
Sbjct: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 217 HPTHGRCD---RPGDCDCRPGWRGELC----SQCQPYPGCKHG-YCNG--SSWDCTCDTN 266
G C C C PG+ G+ C ++C P CK+G C+ +S+ C C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQAG 978
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G+ C+ ++N C T C +GGTC + + + C C GF+G C N C+ PC +
Sbjct: 979 FDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 327 -GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
GTC GT R C+C G+ G + PC + +C C C GW
Sbjct: 1037 EGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 385 TGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G C C + G L C ++ C N + C C G+TG CE +D+C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 443 TGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C HGATC D + + C C GY G C +VD+C +PC NGG C+DL+N ++C C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 502 PVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
P G G CE++ D CA P C NG C Y C C PG+ G+ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE----------- 1262
Query: 561 VLVEESERCAEGMCANGGT--CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
+ C C++ G+ C++ + ++
Sbjct: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET---FVDVCPQMPCLNG 1316
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G + S +P G+ C C G +GA C+ S CG CR G +CV + C C +
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 679 GET-CAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRC-LCPAPPQRAARRCLETVAGLE 736
E+ CA S +RC L APP CL +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 737 AEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNA---CWCSGGVPTCTRL 793
A D N +H DG G C + W C++ CW C L
Sbjct: 1434 ARDGVCDEACN-SHACQ-------WDG-GDCSLTMENPWANCSSPLPCWDYIN-NQCDEL 1483
Query: 794 WCGLPDCLAPN 804
C +CL N
Sbjct: 1484 -CNTVECLFDN 1493
Score = 97.1 bits (231), Expect = 3e-19
Identities = 95/360 (26%), Positives = 136/360 (37%), Gaps = 52/360 (14%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPG--DCDCRPGWR 236
D H+ C+ C PG +G CE+ + C G H +G +C DR G C C PG+
Sbjct: 1204 DLVNHFKCS------CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 237 GELC----SQCQPYPGCKHGYCN----GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
GE C ++C P G + + + C C + + G C+ ++ C PC +G
Sbjct: 1258 GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-PQMPCLNG 1316
Query: 289 GTCE--NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
GTC + PD + CRC GFSG C+ + C C G T G C C
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGE-QCVHTASGPRCFCP--- 1369
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEG 404
AS PC HG SC ++C+CA ++G C S T
Sbjct: 1370 ---SPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT-- 1424
Query: 405 ALGP-CVNAA---ACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFH 460
L C + A C+ ++C W G DC +++ C C D +++
Sbjct: 1425 CLSQYCADKARDGVCDEACNSHACQ----WDGGDCSLTMENPWANCSSPLPCWDYINN-- 1478
Query: 461 CACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C C D +C + C C D C G + C D CA
Sbjct: 1479 -QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNH--CDQGCNSEECGWDGLDCA 1535
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 293 bits (720), Expect = 2e-78
Identities = 164/503 (32%), Positives = 221/503 (43%), Gaps = 46/503 (9%)
Query: 198 CLPGWQGDNCEKPV--CK-EGCHPTHGRCDRPGD--CDCRPGWRGELC---SQCQPYPGC 249
C+ GW GD+C + + C C P DR C C G G LC C P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCH 385
Query: 250 KHGYCN----GSSWDCTCDTNWGGILCDQDLNYCG--THEPCQHGGTCENTAPDQYFCRC 303
K C+ + CTC + G C +D++ C PC+H G C NT + C C
Sbjct: 386 KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
+G++G CE N C PC + L GFTC C G+ G S PC
Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
++ C D ++ F C C G+TGP C D+D+CS PC+N A C + GY
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--------PCLNGAKCIDHPNGYE 555
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+TG CE N+D+C H C D +D + C C GY G CS +D+C P
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G C+DL+N Y+C C G SG NCE + D CA +PC +G C + Y C C+PG+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGF 674
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
TG+ C ++ ++E CA C G TC+ +R S
Sbjct: 675 TGQRC-----------NIDIDE---CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GG G+ C C G G CE+ + C S+PC+NGG C
Sbjct: 721 VNECLSNPCIHGNCTGGLS-------GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 664 GGSGWWMCECVAGWTGETCAVRV 686
+ C C G+ G C V +
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVNI 796
Score = 289 bits (708), Expect = 4e-77
Identities = 168/527 (31%), Positives = 235/527 (44%), Gaps = 68/527 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G C D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + C C G+TG C + E C+ C N GTCV G
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFC--------------LHEINECSSHPCLNEGTCVDGLG 1045
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
++R + + GTC+ C C G GA C+
Sbjct: 1046 TYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTCVQKKAES--QCLCPSGWAGAYCD 1099
Query: 646 ---LSLDLCGSSP-------CRNGGRCVGGSGWWMCECVAGWTGETC 682
+S D+ S C++ G C+ C+C G+TG C
Sbjct: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Score = 285 bits (700), Expect = 4e-76
Identities = 165/510 (32%), Positives = 240/510 (47%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
CL G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CLQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 281 bits (690), Expect = 7e-75
Identities = 162/514 (31%), Positives = 234/514 (45%), Gaps = 54/514 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C ++PC+NGG C+ G + C C+ G+TG+ C
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 262 bits (642), Expect = 4e-69
Identities = 149/513 (29%), Positives = 233/513 (45%), Gaps = 58/513 (11%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G C+ N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Y C C PG+ G NC E + C C NGGTC+ ++
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ GG C+ G++C C G G CE ++ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLN---GGQCMDRI--GGYSCRCLPGFAGERCEGDINEC 1268
Query: 652 GSSPCRNGGR--CVGGSGWWMCECVAGWTGETC 682
S+PC + G C+ + ++C C + +TG C
Sbjct: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Score = 260 bits (638), Expect = 1e-68
Identities = 158/526 (30%), Positives = 229/526 (43%), Gaps = 62/526 (11%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSLDLCGSSP-CRNGGRCVGGSGWWMCECVAGWTGETC 682
G G LCE ++D C P C NGG+C+ G + C C+ G+ GE C
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Score = 260 bits (638), Expect = 1e-68
Identities = 167/544 (30%), Positives = 221/544 (40%), Gaps = 64/544 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G C
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G+ G NCE + D C PC NG C + + C C PG G C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE------------- 1223
Query: 563 VEESERCAEG-MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
E + CA G C NGG C+ G + + +
Sbjct: 1224 -ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLD 1280
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW---WMCECVAGWT 678
C+ L + C CR TG CE +D+C PC NGG C S ++C C G++
Sbjct: 1281 CI--QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 679 GETC 682
G C
Sbjct: 1339 GARC 1342
Score = 255 bits (624), Expect = 7e-67
Identities = 149/518 (28%), Positives = 223/518 (43%), Gaps = 57/518 (11%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPV---CKEGCHPTH--GRC---DRPGDCDCRPGWRG 237
G Y CT C G++G +C + V +P G+C D C+C G+ G
Sbjct: 397 GQYICT------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C + C C + G+ C+ ++N C ++ PC + G C
Sbjct: 451 PRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQC 509
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXX 351
+ +++ C C GF+G C+ + C+ PC +G + G+ C C G+ G
Sbjct: 510 VDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYECQCATGFTGVLC 567
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
PC HG C+D +D +TC C G+ G C++ +DEC PC+N
Sbjct: 568 EENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYS--------SPCLN 618
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
C + GY C C G +G +CE N DDC C+HG C+D ++ + C C+ G+ G+
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQ 677
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C++D+D+CA PC G C++ +N +RCICP G +C + C +PC +G C
Sbjct: 678 RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTG 736
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
S Y C C GW G NC V+++E C C NGGTC +R
Sbjct: 737 GLSGYKCLCDAGWVGINCE-------------VDKNE-CLSNPCQNGGTCDNLVNGYRCT 782
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
GTC G+ C C TG C+ L
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQ----GTCFDDI--SGYTCHCVLPYTGKNCQTVLAP 836
Query: 651 CGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRV 686
C +PC N C + + C C GW G+ C + +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Score = 252 bits (618), Expect = 4e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 251 bits (614), Expect = 1e-65
Identities = 187/671 (27%), Positives = 263/671 (39%), Gaps = 67/671 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDK--FGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGC 216
LC P + CT K H C + C PG+ G +CE+ + C
Sbjct: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 217 HPTHGRCD---RPGDCDCRPGWRGELC----SQCQPYPGCKHG-YCNG--SSWDCTCDTN 266
G C C C PG+ G+ C ++C P CK+G C+ +S+ C C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQAG 978
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G+ C+ ++N C T C +GGTC + + + C C GF+G C N C+ PC +
Sbjct: 979 FDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 327 -GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
GTC GT R C+C G+ G + PC + +C C C GW
Sbjct: 1037 EGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 385 TGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G C C + G L C ++ C N + C C G+TG CE +D+C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 443 TGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C HGATC D + + C C GY G C +VD+C +PC NGG C+DL+N ++C C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 502 PVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
P G G CE++ D CA P C NG C Y C C PG+ G+ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE----------- 1262
Query: 561 VLVEESERCAEGMCANGGT--CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
+ C C++ G+ C++ + ++
Sbjct: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET---FVDVCPQMPCLNG 1316
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G + S +P G+ C C G +GA C+ S CG CR G +CV + C C +
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 679 GET-CAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRC-LCPAPPQRAARRCLETVAGLE 736
E+ CA S +RC L APP CL +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 737 AEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNA---CWCSGGVPTCTRL 793
A D N +H DG G C + W C++ CW C L
Sbjct: 1434 ARDGVCDEACN-SHACQ-------WDG-GDCSLTMENPWANCSSPLPCWDYIN-NQCDEL 1483
Query: 794 WCGLPDCLAPN 804
C +CL N
Sbjct: 1484 -CNTVECLFDN 1493
Score = 97.1 bits (231), Expect = 3e-19
Identities = 95/360 (26%), Positives = 136/360 (37%), Gaps = 52/360 (14%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHG-RC-DRPG--DCDCRPGWR 236
D H+ C+ C PG +G CE+ + C G H +G +C DR G C C PG+
Sbjct: 1204 DLVNHFKCS------CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA 1257
Query: 237 GELC----SQCQPYPGCKHGYCN----GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
GE C ++C P G + + + C C + + G C+ ++ C PC +G
Sbjct: 1258 GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-PQMPCLNG 1316
Query: 289 GTCE--NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
GTC + PD + CRC GFSG C+ + C C G T G C C
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGE-QCVHTASGPRCFCP--- 1369
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEG 404
AS PC HG SC ++C+CA ++G C S T
Sbjct: 1370 ---SPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT-- 1424
Query: 405 ALGP-CVNAA---ACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFH 460
L C + A C+ ++C W G DC +++ C C D +++
Sbjct: 1425 CLSQYCADKARDGVCDEACNSHACQ----WDGGDCSLTMENPWANCSSPLPCWDYINN-- 1478
Query: 461 CACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C C D +C + C C D C G + C D CA
Sbjct: 1479 -QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNH--CDQGCNSEECGWDGLDCA 1535
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 293 bits (720), Expect = 2e-78
Identities = 164/503 (32%), Positives = 221/503 (43%), Gaps = 46/503 (9%)
Query: 198 CLPGWQGDNCEKPV--CK-EGCHPTHGRCDRPGD--CDCRPGWRGELC---SQCQPYPGC 249
C+ GW GD+C + + C C P DR C C G G LC C P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCH 385
Query: 250 KHGYCN----GSSWDCTCDTNWGGILCDQDLNYCG--THEPCQHGGTCENTAPDQYFCRC 303
K C+ + CTC + G C +D++ C PC+H G C NT + C C
Sbjct: 386 KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
+G++G CE N C PC + L GFTC C G+ G S PC
Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
++ C D ++ F C C G+TGP C D+D+CS PC+N A C + GY
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--------PCLNGAKCIDHPNGYE 555
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+TG CE N+D+C H C D +D + C C GY G CS +D+C P
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C N G C+DL+N Y+C C G SG NCE + D CA +PC +G C + Y C C+PG+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGF 674
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
TG+ C ++ ++E CA C G TC+ +R S
Sbjct: 675 TGQRC-----------NIDIDE---CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GG G+ C C G G CE+ + C S+PC+NGG C
Sbjct: 721 VNECLSNPCIHGNCTGGLS-------GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 664 GGSGWWMCECVAGWTGETCAVRV 686
+ C C G+ G C V +
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVNI 796
Score = 289 bits (708), Expect = 4e-77
Identities = 168/527 (31%), Positives = 235/527 (44%), Gaps = 68/527 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQG-------DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGW 235
D YSC C PG+ G D C C++G +G C C G
Sbjct: 661 DGINRYSCV------CSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGP 712
Query: 236 RGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGG 289
C ++C P C HG C G S + C CD W GI C+ D N C ++ PCQ+GG
Sbjct: 713 HHPSCYSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGG 770
Query: 290 TCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
TC+N + Y C C +GF G +C+ + CA PC + GTC G+TC C + G
Sbjct: 771 TCDNLV-NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF--DDISGYTCHCVLPYTG 827
Query: 349 XXXXXXXXXXASGPCLHGASCRD--HLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL 406
+ PC + A C++ + + +TC CA GW G C D+DEC +
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK------- 880
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
PC+N C+NT G Y C C G++G DCE ++DDC C +G +C+D V+ F C C
Sbjct: 881 -PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
G+ G C D+++C PC NGG C D +N+Y C C GF G +CE++ + C S C NG
Sbjct: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + C C G+TG C + E C+ C N GTCV G
Sbjct: 1000 GTCVDGINSFSCLCPVGFTGSFC--------------LHEINECSSHPCLNEGTCVDGLG 1045
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
++R + + GTC+ C C G GA C+
Sbjct: 1046 TYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTCVQKKAES--QCLCPSGWAGAYCD 1099
Query: 646 ---LSLDLCGSSP-------CRNGGRCVGGSGWWMCECVAGWTGETC 682
+S D+ S C++ G C+ C+C G+TG C
Sbjct: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Score = 283 bits (693), Expect = 3e-75
Identities = 164/510 (32%), Positives = 239/510 (46%), Gaps = 56/510 (10%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ----CQPY 246
C G+ G C+ P C G C + GD C+C PG+ G C + C P
Sbjct: 209 CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-PN 266
Query: 247 PGCKHG-YC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCR 302
C++G C +G ++++C C W G C +D++ C CQ+GGTC N Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG-YGCV 325
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
C G+SG DC + CA C G+ + F+C C G G S P
Sbjct: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCHLDDACI-SNP 383
Query: 363 CLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA C + L+G + C C G+ G C EDVDEC+ + PC +A C NT G
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN-----PCEHAGKCVNTDG 438
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
+ C CL G+ G CE ++++C + C + ATC+D + F C C G+ G C L++++C
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC 498
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC N G+CVD +N ++C+CP GF+G C+ D D C+ +PC NGA C + Y C C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG---GTCVREEGSWRXXXXXXXX 596
A G+TG C + C + + C G C +G TC+ G
Sbjct: 559 ATGFTGVLCEENI----DNC-----DPDPCHHGQCQDGIDSYTCICNPG----------- 598
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ G C+ L G+ C C+ G +G CE++ D C S+PC
Sbjct: 599 --YMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ G C+ G + C C G+TG+ C + +
Sbjct: 655 IH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 281 bits (690), Expect = 7e-75
Identities = 162/514 (31%), Positives = 234/514 (45%), Gaps = 54/514 (10%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
DK G ++C C+PG++G +CE + C+ +G+C D+ C C PG+ G
Sbjct: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 238 ELCS----QCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
+C C P C + + ++C C T + G+LC+++++ C +PC HG C
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP-DPCHHG-QC 584
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXX 350
++ D Y C C G+ G C + C PC + G C G+ C C G G
Sbjct: 585 QDGI-DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVN 641
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
AS PC+HG C D ++ ++C C+ G+TG C D+DEC A PC
Sbjct: 642 CEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDEC--------ASNPCR 692
Query: 411 NAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
A C N G+ C C G C + V++C + C+HG C + + C C AG+ G
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVG 751
Query: 470 RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
C +D ++C PC NGG C +L+N YRC C GF G NC+ + D CA +PC N C+
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Query: 530 TAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
S Y CHC +TGKNC T A C E + C E TC+ G W+
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPC----ENAAVCKESPNFESYTCLCAPG-WQ 866
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
G C + C C G +G CE +
Sbjct: 867 GQRCTIDIDECISKPCMNH------------GLC--HNTQGSYMCECPPGFSGMDCEEDI 912
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C ++PC+NGG C+ G + C C+ G+TG+ C
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Score = 273 bits (669), Expect = 2e-72
Identities = 151/513 (29%), Positives = 225/513 (43%), Gaps = 59/513 (11%)
Query: 197 HCLPGWQGDNCEKPVCKEGCHPTHGRCDRPG---------DCDCRPGWRGELCS----QC 243
+CLPG++G CE+ + + C P H RC G +C C P W G+ C+ +C
Sbjct: 247 NCLPGFEGSTCERNI--DDC-PNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 244 QPYP-GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
P C++ G C + C C W G C ++++ C C G TC + +
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVA-SF 360
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C EG +G+ C +D+ C PC G C + CTC +G+ G
Sbjct: 361 SCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 359 A---SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
A S PC H C + F CEC G+ GP C D++EC PC N A C
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS--------DPCQNDATC 471
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GG++C C+ G+ G CE +++C + C++ C+D V+ F C C G+ G C +
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
D+DDC+ PC NG +C+D N Y C C GF+G CE++ D+C PC +G C
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDS 590
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y C C PG+ G C+ ++ + C C N G C+ ++
Sbjct: 591 YTCICNPGYMGAICS--------------DQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
+ G C+ ++C C G TG C + +D C S+
Sbjct: 637 TSGVNCEINFDDCASNPCIH-----GICMDGI--NRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
PCR G C+ G + C C G +C +V+
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Score = 262 bits (642), Expect = 4e-69
Identities = 149/513 (29%), Positives = 233/513 (45%), Gaps = 58/513 (11%)
Query: 197 HCLPGWQGDNCEK---PVCKEGCHPTHGRCDRPG----DCDCRPGWRGELCS----QCQP 245
HC+ + G NC+ P C + P C C PGW+G+ C+ +C
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
P HG C+ + S+ C C + G+ C++D++ C + PCQ+GG+C + + + C C
Sbjct: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMDGV-NTFSCLC 937
Query: 304 AEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP 362
GF+G C+ N C +PC +G TCS +TC C G+ G
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCS--DYVNSYTCKCQAGFDGVHCENNINECTESS 995
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
C +G +C D ++ F+C C G+TG C +++ECS PC+N C + G Y
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH--------PCLNEGTCVDGLGTY 1047
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDD 478
C+C G+TG++C+T V+ C+ C + TC+ + C C +G+AG C ++ D
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
A R C + G C++ N + C CP+G++G+ CE+ D CA +PC +GA C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Y C C PG+ G NC E + C C NGGTC+ ++
Sbjct: 1168 IGGYRCECVPGYQGVNCEY--------------EVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ GG C+ G++C C G G CE ++ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLN---GGQCMDRI--GGYSCRCLPGFAGERCEGDINEC 1268
Query: 652 GSSPCRNGGR--CVGGSGWWMCECVAGWTGETC 682
S+PC + G C+ + ++C C + +TG C
Sbjct: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Score = 260 bits (638), Expect = 1e-68
Identities = 158/526 (30%), Positives = 229/526 (43%), Gaps = 62/526 (11%)
Query: 182 DDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP--THGRC--DRPG-DCDCRPGWR 236
D+ Y CT C G++G NC+ + + +P G C D G C C +
Sbjct: 773 DNLVNGYRCT------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT 826
Query: 237 GELC----SQCQPYPGCKHGYC----NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
G+ C + C P P C N S+ C C W G C D++ C +PC +
Sbjct: 827 GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNH 885
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
G C NT Y C C GFSG+DCE + C PC +G + G F+C C G+ G
Sbjct: 886 GLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTG 943
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S PC +G +C D+++ +TC+C G+ G C +++EC+ S
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-------- 995
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C N C + +SC C G+TG C +++C+ CL+ TC+D + + C+C GY
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP---- 521
G+ C V+ C+ PC N G CV +C+CP G++G C+ C A S
Sbjct: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
C + C A + +YC C G+TG C E+ + CA C +G
Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE--------------EQLDECASNPCQHG 1161
Query: 578 GTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCRE 637
TC G +R + Q GGTC+ L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE----YEVDECQNQPCQNGGTCID--LVNHFKCSCPP 1215
Query: 638 GRTGALCELSLDLCGSSP-CRNGGRCVGGSGWWMCECVAGWTGETC 682
G G LCE ++D C P C NGG+C+ G + C C+ G+ GE C
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Score = 260 bits (638), Expect = 1e-68
Identities = 167/544 (30%), Positives = 221/544 (40%), Gaps = 64/544 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGR 222
C PN C+ F Y+C C PGWQG C + C HG
Sbjct: 837 CSPNPCENAAV--CK-ESPNFESYTCL------CAPGWQGQRCTIDIDECISKPCMNHGL 887
Query: 223 C-DRPGD--CDCRPGWRGELCSQ----CQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCD 273
C + G C+C PG+ G C + C P G C +G +++ C C + G C
Sbjct: 888 CHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAG 333
D+N C EPC++GGTC + + Y C+C GF GV CE N C C +G + G
Sbjct: 948 TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
F+C C G+ G +S PCL+ +C D L + C C G+TG C V
Sbjct: 1006 IN-SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET-NVD-DCTGQ------ 445
+ CS RS PC N C C C +GW G C+ NV D
Sbjct: 1065 NLCS-RS-------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 446 ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
C H CI+ + +C C GY G C +D+CA PC +G C D + YRC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G+ G NCE + D C PC NG C + + C C PG G C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE------------- 1223
Query: 563 VEESERCAEG-MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
E + CA G C NGG C+ G + + +
Sbjct: 1224 -ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLD 1280
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW---WMCECVAGWT 678
C+ L + C CR TG CE +D+C PC NGG C S ++C C G++
Sbjct: 1281 CI--QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 679 GETC 682
G C
Sbjct: 1339 GARC 1342
Score = 255 bits (624), Expect = 7e-67
Identities = 149/518 (28%), Positives = 223/518 (43%), Gaps = 57/518 (11%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPV---CKEGCHPTH--GRC---DRPGDCDCRPGWRG 237
G Y CT C G++G +C + V +P G+C D C+C G+ G
Sbjct: 397 GQYICT------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
Query: 238 ELC----SQCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C ++C P C + C C + G+ C+ ++N C ++ PC + G C
Sbjct: 451 PRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQC 509
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXX 351
+ +++ C C GF+G C+ + C+ PC +G + G+ C C G+ G
Sbjct: 510 VDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYECQCATGFTGVLC 567
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
PC HG C+D +D +TC C G+ G C++ +DEC PC+N
Sbjct: 568 EENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYS--------SPCLN 618
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
C + GY C C G +G +CE N DDC C+HG C+D ++ + C C+ G+ G+
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQ 677
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C++D+D+CA PC G C++ +N +RCICP G +C + C +PC +G C
Sbjct: 678 RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTG 736
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
S Y C C GW G NC V+++E C C NGGTC +R
Sbjct: 737 GLSGYKCLCDAGWVGINCE-------------VDKNE-CLSNPCQNGGTCDNLVNGYRCT 782
Query: 591 XXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL 650
GTC G+ C C TG C+ L
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQ----GTCFDDI--SGYTCHCVLPYTGKNCQTVLAP 836
Query: 651 CGSSPCRNGGRCVGGSGW--WMCECVAGWTGETCAVRV 686
C +PC N C + + C C GW G+ C + +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Score = 254 bits (621), Expect = 2e-66
Identities = 162/542 (29%), Positives = 233/542 (42%), Gaps = 56/542 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDG--DKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
C+ Y C + G+ C P+G ++C D CEK C+ G
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKC-PEGFLGEYCQ---HRDPCEKNRCQNGGTCVAQA 83
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYP-----GCKHG----YCNGSSWDCTCDTNWGGILCD 273
C C G+ GE C +P C +G + +++CTC + G C
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC- 142
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-APQPCAHG-TC-S 330
Q + C +H PC +G TC T +Q+ C+C GF+G CE N C P C HG TC +
Sbjct: 143 QWTDACLSH-PCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPAC 389
L G+ + C C +G+ G A PC++G +CR D F C C G+ G C
Sbjct: 201 LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ---C 446
++D+C C N C + Y+C C WTG+ C +VD+C Q C
Sbjct: 258 ERNIDDCPNHR--------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC 309
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS 506
+G TC + + C C G++G CS ++DDCA CT G C+D + ++ C+CP G +
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
G C D D C +PC GA C T Y C C G+ G +CT+ V+
Sbjct: 370 GLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED-----------VD 417
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP 624
E C + G CV +G++ + Q TCL
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINECHSDPCQNDATCLD 473
Query: 625 SALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C C G G CEL ++ C S+PC N G+CV + C C G+TG C +
Sbjct: 474 KI--GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Query: 685 RV 686
+
Sbjct: 532 DI 533
Score = 251 bits (614), Expect = 1e-65
Identities = 187/671 (27%), Positives = 263/671 (39%), Gaps = 67/671 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDK--FGHYSCTPDGDKH---CLPGWQGDNCEKPV--CKEGC 216
LC P + CT K H C + C PG+ G +CE+ + C
Sbjct: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 217 HPTHGRCD---RPGDCDCRPGWRGELC----SQCQPYPGCKHG-YCNG--SSWDCTCDTN 266
G C C C PG+ G+ C ++C P CK+G C+ +S+ C C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQAG 978
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G+ C+ ++N C T C +GGTC + + + C C GF+G C N C+ PC +
Sbjct: 979 FDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 327 -GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
GTC GT R C+C G+ G + PC + +C C C GW
Sbjct: 1037 EGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 385 TGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G C C + G L C ++ C N + C C G+TG CE +D+C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 443 TGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C HGATC D + + C C GY G C +VD+C +PC NGG C+DL+N ++C C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 502 PVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
P G G CE++ D CA P C NG C Y C C PG+ G+ C
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE----------- 1262
Query: 561 VLVEESERCAEGMCANGGT--CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
+ C C++ G+ C++ + ++
Sbjct: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET---FVDVCPQMPCLNG 1316
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G + S +P G+ C C G +GA C+ S CG CR G +CV + C C +
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 679 GET-CAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRC-LCPAPPQRAARRCLETVAGLE 736
E+ CA S +RC L APP CL +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 737 AEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNA---CWCSGGVPTCTRL 793
A D N +H DG G C + W C++ CW C L
Sbjct: 1434 ARDGVCDEACN-SHACQ-------WDG-GDCSLTMENPWANCSSPLPCWDYIN-NQCDEL 1483
Query: 794 WCGLPDCLAPN 804
C +CL N
Sbjct: 1484 -CNTVECLFDN 1493
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
Score = 57.6 bits (133), Expect = 2e-07
Identities = 60/217 (27%), Positives = 79/217 (36%), Gaps = 23/217 (10%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHG-YC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPC 285
C C PG+ G C C+ G C S C C + C+ C + PC
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD---CESG---CAS-SPC 1383
Query: 286 QHGGTCE-NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC--TC 342
QHGG+C P Y C+CA FSG CE P + P + A R C C
Sbjct: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEAC 1443
Query: 343 DR---GW-GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSG 398
+ W GG A+ C C D+++ +C + C D EC G
Sbjct: 1444 NSHACQWDGGDCSLTMENPWAN--CSSPLPCWDYINN---QCDELCNTVECLFDNFECQG 1498
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
S T C + N+ G + GW G DC
Sbjct: 1499 NSKTCKYDKYCADHFKDNHCNQGCNSE-ECGWDGLDC 1534
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 614 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 671
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 672 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 727
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 728 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 786
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 787 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 839
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 840 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 899
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 900 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 959
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 960 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1004
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1005 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1061
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1062 ATAGSPLGFICHCPKGFEGPTCSHR 1086
Score = 268 bits (658), Expect = 5e-71
Identities = 166/530 (31%), Positives = 226/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 221 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNC 279
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C P C++GGTC+N+A
Sbjct: 280 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSA- 335
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 336 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 394
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 395 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 450
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 451 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 510
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 511 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 570
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 571 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 616
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 617 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 676
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 677 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 726
Score = 252 bits (616), Expect = 6e-66
Identities = 163/549 (29%), Positives = 221/549 (40%), Gaps = 53/549 (9%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQ--GDNCEKPVCKEGCHPTHGR 222
C P + T P D H P G PG + DNC C+ G G
Sbjct: 237 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPG--FIGPGCEVNPDNCVSHQCQNG-----GT 289
Query: 223 CDRPGD---CDCRPGWRGELCSQ------CQPYPGCKHG-YCNGS--SWDCTCDTNWGGI 270
C D C C W G CS+ Q P C++G C S S+ C C + WGG
Sbjct: 290 CQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGT 349
Query: 271 LCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-- 328
C+++L+ C C G TC + + C C G +G+ C +++ C QPC HG
Sbjct: 350 SCEENLDDC-IAATCAPGSTCIDRV-GSFSCLCPPGRTGLLCH-LEDMCLSQPC-HGDAQ 405
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXX-----XXXASGPCLHGASCRDHLDGFTCECADG 383
CS T C C G+ G PC HG SC + F C C G
Sbjct: 406 CSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG 465
Query: 384 WTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC- 442
+TG C D +EC + PC + C + + C C G G+ CE ++C
Sbjct: 466 YTGSRCEADHNECLSQ--------PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECA 517
Query: 443 TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICP 502
+ CL+ A C DL++ F C C G++G C D+D+C PC NGG+C D A+ C C
Sbjct: 518 SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCL 577
Query: 503 VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK-----NCTQRAARDRK 557
GF G C+ + D C PC GA+C ++C C G+TG+ C + ++
Sbjct: 578 PGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQ 637
Query: 558 TCSVLVEESE-RCAEGM--CA-NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
C +++ C +G CA C G +
Sbjct: 638 ICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 697
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
GGTC P P G+ C C G TG C + C S PC NGG C G + C C
Sbjct: 698 PCAH-GGTCYPQ--PSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 754
Query: 674 VAGWTGETC 682
TG C
Sbjct: 755 PPSHTGPQC 763
Score = 250 bits (611), Expect = 2e-65
Identities = 134/377 (35%), Positives = 176/377 (46%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 104 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 161
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 162 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 220
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 221 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCV 280
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC + C N C N+A
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPH-----CRNGGTCQNSA 335
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 336 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 394
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 395 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 454
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 455 PGSFNCLCPPGYTGSRC 471
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 660 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 719
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 720 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 778
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 779 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 835
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 836 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 895
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 896 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 955
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 956 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1015
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1016 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1061
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1062 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1120
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1121 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1169
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 418 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 477
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 478 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 537
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 538 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 595
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 596 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 652
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 653 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 694
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 695 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 754
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 755 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 805
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 806 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 857
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 858 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 915
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 916 HCPPGFQGSLCQDHVN 931
Score = 228 bits (557), Expect = 9e-59
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 102 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 160
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 161 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 217
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 218 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPD 277
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 278 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGG 329
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 330 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 389
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 390 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 440
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 441 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 493
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 494 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 547
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 180 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 235
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 236 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQ-CQNGGTCQDGL 294
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 295 -DTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 351
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 352 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 402
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 403 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 462
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 463 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 522
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 523 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 568
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 569 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 622
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 623 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 656
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 537 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 596
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 597 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 651
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 652 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 708
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 709 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 766
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 767 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 818
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 819 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 878
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 879 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 930
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 931 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 980
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 981 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1038
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1039 GQWCEVEI 1046
Score = 200 bits (487), Expect = 3e-50
Identities = 135/430 (31%), Positives = 174/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 27 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 85
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 86 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 145
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 146 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 196
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 197 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 256
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G CE + D+C C NG C Y C C WTG +C++
Sbjct: 257 TFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 313
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 314 --------VDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 364
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 365 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 418
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 419 CQPGYSGPTC 428
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 916 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 975
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 976 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1033
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1034 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1093
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1094 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1148
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1149 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1202
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1203 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1253
Query: 533 SDYYCH 538
D YCH
Sbjct: 1254 YDQYCH 1259
Score = 81.8 bits (193), Expect = 1e-14
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 34 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 92
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 93 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 152
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 153 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 194
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 195 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 253
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 254 KDSTFHLCLCPPGFIGPGCEV 274
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 31 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 89
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 90 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 135
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 136 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 190
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 191 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 233
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 26 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 61
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 272 bits (667), Expect = 4e-72
Identities = 161/505 (31%), Positives = 214/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 617 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 674
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 675 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 730
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 731 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 789
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 790 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 842
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 843 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 902
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 903 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 962
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 963 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1007
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1008 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1064
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1065 ATAGSPLGFICHCPKGFEGPTCSHR 1089
Score = 268 bits (658), Expect = 5e-71
Identities = 166/530 (31%), Positives = 226/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 224 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 282
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C P C++GGTC+N+A
Sbjct: 283 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSA- 338
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 339 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 397
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 398 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 453
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 454 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 513
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 514 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 573
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 574 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 619
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 620 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 679
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 680 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 729
Score = 250 bits (611), Expect = 2e-65
Identities = 134/377 (35%), Positives = 176/377 (46%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 107 CLPGFTGERCQAQL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 164
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 165 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 223
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 224 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 283
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC + C N C N+A
Sbjct: 284 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPH-----CRNGGTCQNSA 338
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 339 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 397
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 398 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 457
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 458 PGSFNCLCPPGYTGSRC 474
Score = 248 bits (606), Expect = 1e-64
Identities = 165/530 (31%), Positives = 212/530 (40%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 663 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 722
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 723 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 781
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C G+
Sbjct: 782 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTGY 838
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 839 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 898
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 899 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 958
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 959 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1018
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1019 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1064
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1065 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1123
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1124 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1172
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 421 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 480
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 481 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 540
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 541 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 598
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 599 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 655
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 656 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 697
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 698 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 757
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 758 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 808
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 809 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQKPCPRNSH 860
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 861 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 918
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 919 HCPPGFQGSLCQDHVN 934
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 183 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 238
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 239 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 297
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 298 -DTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 354
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 355 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 405
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 406 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 465
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 466 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 525
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 526 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 571
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 572 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 625
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 626 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 659
Score = 227 bits (555), Expect = 2e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 105 CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 163
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 164 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 220
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 221 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 280
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 281 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGG 332
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 333 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 392
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 393 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 443
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 444 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 496
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 497 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 550
Score = 224 bits (547), Expect = 1e-57
Identities = 156/548 (28%), Positives = 202/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 540 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 599
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 600 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 654
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 655 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 711
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 712 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 769
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 770 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 821
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C GY G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 822 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 881
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 882 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 933
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 934 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 983
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 984 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1041
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1042 GQWCEVEI 1049
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 30 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 88
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 89 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCM 148
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 149 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 199
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 200 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 259
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 260 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 316
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 317 --------VDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 367
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 368 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 421
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 422 CQPGYSGPTC 431
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 919 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 978
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 979 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1036
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1037 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1096
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1097 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1151
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1152 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1205
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1206 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1256
Query: 533 SDYYCH 538
D YCH
Sbjct: 1257 YDQYCH 1262
Score = 82.6 bits (195), Expect = 6e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 37 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 95
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 96 PSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 155
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 156 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 197
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 198 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 256
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 257 KDSTFHLCLCPPGFIGPDCEV 277
Score = 60.9 bits (141), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 34 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 92
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 93 PSSPSPLTPSFLCTCLPGFTGERCQAQL-------------EDPCPPSFCSKRGRC-HIQ 138
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 139 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 193
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 194 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 236
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 29 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 64
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAQL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT----LMDLCAQRPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 215 bits (526), Expect = 5e-55
Identities = 120/354 (33%), Positives = 155/354 (43%), Gaps = 28/354 (7%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C G+TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC 954
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 82.6 bits (195), Expect = 6e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 64.5 bits (150), Expect = 2e-09
Identities = 62/242 (25%), Positives = 84/242 (34%), Gaps = 30/242 (12%)
Query: 165 CQPNYYNTTCT---TFCRPRDDKFGHYSCTPD-GDKHCL--PGWQGDNCEKPV--CKEGC 216
C Y TC+ T C G SC P G +C P G C+ C
Sbjct: 717 CPTGYTGPTCSEEMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775
Query: 217 HPTHGRC-DRPG--DCDCRPGWRGELCS-----QCQPYPGCKHGYCNGSSWD--CTCDTN 266
G C +RPG C C G++G C C P C S C C T
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G C ++ C PC C T P + C C +G++G C + C +
Sbjct: 836 YTGGSCQTLMDLCA-QRPCPRNSHCLQTGPS-FHCLCLQGWTGPLCNLPLSSCQKAALSQ 893
Query: 327 GT-----CSLAG----TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
G C G + + C C G+ G S PC +GA+C G+
Sbjct: 894 GIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 378 CE 379
C+
Sbjct: 954 CQ 955
Score = 60.9 bits (141), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAQL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 268 bits (658), Expect = 5e-71
Identities = 160/505 (31%), Positives = 213/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C +TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 244 bits (597), Expect = 1e-63
Identities = 164/530 (30%), Positives = 211/530 (39%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C +
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTVY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 220 bits (538), Expect = 2e-56
Identities = 155/548 (28%), Positives = 201/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C Y G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 270 bits (663), Expect = 1e-71
Identities = 167/530 (31%), Positives = 227/530 (42%), Gaps = 68/530 (12%)
Query: 198 CLPGWQGDNCEK---PVCKEGCHPTHGRCDRPGD-------CDCRPGWRGELCS------ 241
C G +G CE P GC G C + C C PG+ G C
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCS-NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 242 ---QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP--CQHGGTCENTAP 296
QCQ C+ G ++ C C W G C +D++ C T P C++GGTC+N+A
Sbjct: 281 VSHQCQNGGTCQDGL---DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA- 336
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G CE + C CA G+ + F+C C G G
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 357 XXASGPCLHGASCRDH-LDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
S PC A C + L G T C C G++GP C +D+DEC M + PC + +
Sbjct: 396 CL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL---MAQQGPSPCEHGGS 451
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH-GATCIDLVDDFHCACAAGYAGRTCS 473
C NT G ++C C G+TG CE + ++C Q H G+TC+DL+ FHC C G G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQS 533
++ ++CA PC N +C DLLN ++CIC GFSGT CE+D D C SPC NG C
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
++C C PG+ G C E + C C G +C+ G++
Sbjct: 572 AFHCKCLPGFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 594 XXXXXXXD---SXXXXXXXXXXXXXXQAGGTCL-----PSALPPGWACGCREGR------ 639
+ + CL P PP C C G
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 640 ------TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TG CE L C S+PC +GG C + C C G+TG TC+
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
Score = 268 bits (658), Expect = 5e-71
Identities = 160/505 (31%), Positives = 213/505 (42%), Gaps = 49/505 (9%)
Query: 198 CLPGWQGDNCEKPVCKEG-CHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYC 254
C G+ G CE P+C C P D+ +C C G G C+ + C HG+C
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC 672
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
SS C CD W G C+ +L C PC HGGTC P Y C C G++G C
Sbjct: 673 QRSS--CVCDVGWTGPECEAELGGC-ISAPCAHGGTCY-PQPSGYNCTCPTGYTGPTCSE 728
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
C PC +G S + G+ CTC G S PC +G +C +
Sbjct: 729 EMTACHSGPCLNGG-SCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
F+C CA G+ GP C G+ A PC N A C ++ G C C +TG
Sbjct: 788 TFSCLCAMGFQGP-------RCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGS 840
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP---------- 483
C+T +D C + C + C+ FHC C G+ G C+L + C
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C NGG CVD +Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G+NC+ +E + C C N GTC + G + +
Sbjct: 961 DGQNCS--------------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG- 1005
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
GT +L + C C G TG CE+ +D C S PC +GG C
Sbjct: 1006 ---DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 664 GGSG---WWMCECVAGWTGETCAVR 685
+G ++C C G+ G TC+ R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 250 bits (612), Expect = 2e-65
Identities = 136/377 (36%), Positives = 178/377 (47%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAH-GTCSL--AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++ GTC L + C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECV--DLLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 456 PGSFNCLCPPGYTGSRC 472
Score = 244 bits (597), Expect = 1e-63
Identities = 164/530 (30%), Positives = 211/530 (39%), Gaps = 47/530 (8%)
Query: 180 PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPG 234
P D+ H+ C GW G CE + C G C +P +C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 235 WRGELCSQ----CQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
+ G CS+ C P G CN S + CTC + G C +YC PC +G
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC-VSAPCFNG 779
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNP-CAPQPCAH-GTCSLAGTTRGFTCTCDRGW 346
GTC N P + C CA GF G CE P CA PC + TC + +G C C +
Sbjct: 780 GTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ--DSPQGPRCLCPTVY 836
Query: 347 GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEG-- 404
G A PC + C F C C GWTGP C + C ++++G
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCAC 463
C N C ++ Y C C G+ G C+ +V+ C + C +GATC+ + C C
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
A GY G+ CS ++D C +PC N G C + C CP GF G CE D D C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 524 --NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
AAC++ + +YC C PG TG+ C E + C C +GGTC
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEV--------------EIDPCHSQPCFHGGTCE 1062
Query: 582 REEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS---ALPPGWACGCREG 638
GS GG CLPS PP AC G
Sbjct: 1063 ATAGS-PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 639 RTGALCELSLDLCG-SSPCRNGGRC-----VGGSGWWMCECVAGWTGETC 682
L + CG SPC G C +GG G + C C G C
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG-FRCSCPHSSPGPRC 1170
Score = 233 bits (570), Expect = 2e-60
Identities = 160/556 (28%), Positives = 209/556 (37%), Gaps = 74/556 (13%)
Query: 164 LCQPNYYNTTC---TTFCR-----PRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCDRPGD--CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
PC G L F C C G+ G A C C+D D C C D
Sbjct: 597 PCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLC--APNLCQPKQICKDQKDKANCLCPD 653
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC 442
G P CA D C+ G C + SC C GWTG +CE + C
Sbjct: 654 G--SPGCAPPEDNCTCHH------GHCQRS----------SCVCDVGWTGPECEAELGGC 695
Query: 443 -TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
+ C HG TC ++C C GY G TCS ++ C PC NGG C Y C C
Sbjct: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
P +G C+ D+C +PC NG C + C CA G+ G C +
Sbjct: 756 PPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL--------- 806
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
CA+ C N TC R +
Sbjct: 807 ----RPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT----LMDLCAQKPCPRNSH 858
Query: 622 CLPSALPPGWACGCREGRTGALCELSLDLCG----------SSPCRNGGRCVGGSGWWMC 671
CL + P + C C +G TG LC L L C SS C NGG CV + C
Sbjct: 859 CLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 672 ECVAGWTGETCAVRVS 687
C G+ G C V+
Sbjct: 917 HCPPGFQGSLCQDHVN 932
Score = 227 bits (556), Expect = 1e-58
Identities = 155/516 (30%), Positives = 217/516 (42%), Gaps = 72/516 (13%)
Query: 197 HCLPGWQGDNCEKPV---------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS-QCQ 244
HC PG++G CE+ V C +G CH T G C C G G C +
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ----CLCPVGQEGPRCELRAG 236
Query: 245 PYP--GCKHG-YCN-----GSSWD-CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
P P GC +G C S++ C C + G C+ + + C +H+ CQ+GGTC++
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAH----GTCSLAGTTRGFTCTCDRGWGGXXX 351
D Y C C E ++G DC + C Q H GTC + F C C GWGG
Sbjct: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ--NSAGSFHCVCVSGWGGTSC 352
Query: 352 XXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN 411
+ C G++C D + F+C C G TG C + D C + PC
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ--------PCHG 403
Query: 412 AAAC--NNTAGGYSCACLAGWTGRDCETNVDDCT------GQCLHGATCIDLVDDFHCAC 463
A C N G C C G++G C ++D+C C HG +C++ F+C C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY G C D ++C +PC G C+DLL + C+CP G G CE + + CA +PC
Sbjct: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
N A C+ + + C C PG++G C E+ + C CANGG C +
Sbjct: 524 NHADCHDLLNGFQCICLPGFSGTRCE--------------EDIDECRSSPCANGGQCQDQ 569
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
G++ + G +CL LP + C C G TG L
Sbjct: 570 PGAFHCKCLPGFEGPRCQT----EVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQL 623
Query: 644 CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
CE + LC + C+ C C C G G
Sbjct: 624 CE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 220 bits (538), Expect = 2e-56
Identities = 155/548 (28%), Positives = 201/548 (36%), Gaps = 63/548 (11%)
Query: 164 LCQPNYYNTTCTTF---CRPRDDKFGHYSCTPDGDKHC--LPGWQGDNCEKPV--CKEGC 216
+C P + T C CR G G HC LPG++G C+ V C
Sbjct: 538 ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 217 HPTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
P C D PG C C G+ G+LC P C C C + LC
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCE----VPLCAPNLCQPKQI-CKDQKDKANCLCP 652
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLA 332
C P + TC + + C C G++G +CE C PCAHG TC
Sbjct: 653 DGSPGCA---PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED 392
+ G+ CTC G+ G SGPCL+G SC G+ C C TGP C
Sbjct: 710 PS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 393 VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQ-CLHGA 450
D C PC N C N G +SC C G+ G CE + C C + A
Sbjct: 768 TDYCVS--------APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC D C C Y G +C +D CA +PC C+ ++ C+C G++G C
Sbjct: 820 TCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 511 EDDRDHC----------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C S C NG C + Y+CHC PG+ G C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------- 931
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
C C NG TC+ + + G
Sbjct: 932 ------NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH----G 981
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG--RCVGGSGWWMCECVAGWT 678
TC P P G+ C C G G CE +D C PC G C + + C+C+ G T
Sbjct: 982 TCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Query: 679 GETCAVRV 686
G+ C V +
Sbjct: 1040 GQWCEVEI 1047
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 1034
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 1035 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 1149
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 1203
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 1204 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 1254
Query: 533 SDYYCH 538
D YCH
Sbjct: 1255 YDQYCH 1260
Score = 82.2 bits (194), Expect = 8e-15
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 153
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 154 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 195
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEV 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 136
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 191
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 261 bits (639), Expect = 1e-68
Identities = 166/519 (31%), Positives = 219/519 (42%), Gaps = 63/519 (12%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 105 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 162
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 163 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 221
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG--FTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++G TC L C C G+ G
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC T+G C N C N+A
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE----TQGP-PHCRNGGTCQNSA 336
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 395
Query: 479 CAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
+ NC C + C C G TC+ ++
Sbjct: 456 PGSF-----------NCLCPPGYTGSRCEA---DHNECLSQPCHPGSTCLDLLATFHCLC 501
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSA----LPPGWACGCREGRTGALCELS 647
+ A CL A L G+ C C G +G CE
Sbjct: 502 PPGLEGQLCEVETNEC----------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEED 551
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C SSPC NGG+C G + C+C+ G+ G C V
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV 590
Score = 231 bits (565), Expect = 9e-60
Identities = 157/543 (28%), Positives = 220/543 (40%), Gaps = 63/543 (11%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCE-KPVCKEGCHPTHGRC 223
CQ + +FC R H + C+PGW G+ C+ + C G C
Sbjct: 114 CQAKLEDPCPPSFCSKRGRC--HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVC 171
Query: 224 --DRPG-DCDCRPGWRGELC----SQCQPYPG-CKHGY-CNGS--SWDCTCDTNWGGILC 272
P C C PG+ G C ++C PG C G C+ + S+ C C G C
Sbjct: 172 LATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRC 231
Query: 273 DQDLNYCGTHEPCQHGGTCENTAPDQ----YFCRCAEGFSGVDCERVDNPCAPQPCAHG- 327
+ C C +GGTC+ P++ + C C GF G DCE + C C +G
Sbjct: 232 ELRAGPCPPRG-CSNGGTCQ-LMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGG 289
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX-XASGP--CLHGASCRDHLDGFTCECADGW 384
TC T +TC C W G GP C +G +C++ F C C GW
Sbjct: 290 TCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW 347
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG 444
G +C E++D+C + C + C + G +SC C G TG C D C
Sbjct: 348 GGTSCEENLDDCIAAT--------CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLS 398
Query: 445 QCLHG-ATCID--LVDDFHCACAAGYAGRTCSLDVDDC-----APRPCTNGGECVDLLNA 496
Q HG A C L C C GY+G TC D+D+C P PC +GG C++ +
Sbjct: 399 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
+ C+CP G++G+ CE D + C PC G+ C + ++C C PG G+ C
Sbjct: 459 FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE------- 511
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
VE +E CA C N C ++ +
Sbjct: 512 ------VETNE-CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCAN-- 562
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
GG C P + C C G G C+ +D C S PC G C+ G + C C +G
Sbjct: 563 --GGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Query: 677 WTG 679
+TG
Sbjct: 619 FTG 621
Score = 226 bits (553), Expect = 3e-58
Identities = 146/474 (30%), Positives = 192/474 (40%), Gaps = 48/474 (10%)
Query: 229 CDCRPGWRGELC-----SQCQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 161
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC--APQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 162 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 218
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 279 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG 330
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 331 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 391 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 441
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP 628
C +GG+C+ GS+ S G TCL L
Sbjct: 442 -GPSPCEHGGSCLNTPGSFN----CLCPPGYTGSRCEADHNECLSQPCHPGSTCLD--LL 494
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G LCE+ + C S+PC N C + C C+ G++G C
Sbjct: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRC 548
Score = 205 bits (501), Expect = 5e-52
Identities = 140/487 (28%), Positives = 190/487 (39%), Gaps = 46/487 (9%)
Query: 227 GDCDCRPGWRGELCS---QCQPYPGCKHG-YCNG----------------SSWDCTCDTN 266
G C C PG+ GE C CQ C++G C S+ CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G C L C G C A + C C G++G C+ D C+ PC +
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF-CSANPCVN 167
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS--GPCLHGASCRDHLDGFTCECADGW 384
G LA T C C G+ G GPC G SC + L F C C G
Sbjct: 168 GGVCLA-TYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ 226
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG 444
GP C C R + G G C ++T + C C G+ G DCE N D+C
Sbjct: 227 EGPRCELRAGPCPPRGCSNG--GTCQLMPEKDSTF--HLCLCPPGFIGPDCEVNPDNCVS 282
Query: 445 -QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNAYRCI 500
QC +G TC D +D + C C + G CS DVD+C P C NGG C + ++ C+
Sbjct: 283 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 501 CPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C G+ GT+CE++ D C + C G+ C + C C PG TG C + C
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC- 401
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
+C+ C+ + G + GG
Sbjct: 402 ---HGDAQCSTNPLTGSTLCLCQPG--------YSGPTCHQDLDECLMAQQGPSPCEHGG 450
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
+CL + P + C C G TG+ CE + C S PC G C+ + C C G G+
Sbjct: 451 SCLNT--PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQ 508
Query: 681 TCAVRVS 687
C V +
Sbjct: 509 LCEVETN 515
Score = 200 bits (488), Expect = 2e-50
Identities = 135/430 (31%), Positives = 175/430 (40%), Gaps = 54/430 (12%)
Query: 279 CGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA-PQPCAH-GTC------ 329
CG+ EPC +GGTC + + Q C+CA GF G C+ D PC Q C + G+C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPA 86
Query: 330 ------SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-CLHGASCRDHLDGF-TCECA 381
S + T F CTC G+ G C C G C C
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
GWTG C + D CS PCVN C T C C G+ G CE +V++
Sbjct: 147 PGWTGEQC-QLRDFCSA--------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Query: 442 C---TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL----L 494
C G C G +C + + F C C G G C L C PR C+NGG C +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
+ C+CP GF G +CE + D+C C NG C Y C C WTG +C++
Sbjct: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED--- 314
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
V+E E C NGGTC GS+ +
Sbjct: 315 --------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA- 365
Query: 615 XXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGG--SGWWMCE 672
G TC+ ++C C GRTG LC L D+C S PC +C +G +C
Sbjct: 366 ---PGSTCIDRV--GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 673 CVAGWTGETC 682
C G++G TC
Sbjct: 420 CQPGYSGPTC 429
Score = 181 bits (441), Expect = 1e-44
Identities = 106/332 (31%), Positives = 142/332 (42%), Gaps = 32/332 (9%)
Query: 198 CLPGWQGDNCEKPVCK-EGCHPTH----GRCDRPGD---CDCRPGWRGELCSQ----CQP 245
C W G +C + V + E P H G C C C GW G C + C
Sbjct: 302 CPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIA 361
Query: 246 YPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE-NTAPDQYFCR 302
C S+ C C G+LC + + C +PC C N C
Sbjct: 362 ATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMC-LSQPCHGDAQCSTNPLTGSTLCL 419
Query: 303 CAEGFSGVDCERVDNPC-----APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
C G+SG C + + C P PC HG L T F C C G+ G
Sbjct: 420 CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCL-NTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
S PC G++C D L F C C G G C + +EC A PC+N A C++
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC--------ASAPCLNHADCHD 530
Query: 418 TAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G+ C CL G++G CE ++D+C + C +G C D FHC C G+ G C +V
Sbjct: 531 LLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV 590
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
D+C PC G C+DL A+ C+CP GF+G+
Sbjct: 591 DECLSDPCPVGASCLDLPGAFFCLCPSGFTGS 622
Score = 92.3 bits (219), Expect = 8e-18
Identities = 61/206 (29%), Positives = 85/206 (41%), Gaps = 24/206 (11%)
Query: 164 LCQPNYYNTTC---TTFC-----RPRDDKFGHYSCTPDGDKHCL--PGWQGDNCE---KP 210
LCQP Y TC C P + G G +CL PG+ G CE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 211 VCKEGCHPTHGRCD--RPGDCDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCT 262
+ CHP D C C PG G+LC ++C P H C+ + + C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C + G C++D++ C + PC +GG C++ P + C+C GF G C+ + C
Sbjct: 539 CLPGFSGTRCEEDIDECRS-SPCANGGQCQD-QPGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGG 348
PC G S F C C G+ G
Sbjct: 597 PCPVG-ASCLDLPGAFFCLCPSGFTG 621
Score = 41.1 bits (92), Expect = 0.019
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 650 LCGS--SPCRNGGRCVGGS-GWWMCECVAGWTGETC 682
LCGS PC NGG C+ S G C+C G+ GETC
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 250 bits (611), Expect = 2e-65
Identities = 134/377 (35%), Positives = 175/377 (46%), Gaps = 35/377 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT----HGRCD-----RPGDCDCRPGWRGELCSQ---CQP 245
CLPG+ G+ C+ + ++ C P+ GRC RP C C PGW GE C C
Sbjct: 104 CLPGFTGERCQAKL-EDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTGEQCQLRDFCSA 161
Query: 246 YPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTAPDQYFCR 302
P G C + C C + G C++D+N C PC G +C NT + C
Sbjct: 162 NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCL 220
Query: 303 CAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG--FTCTCDRGWGGXXXXXXXXXXA 359
C G G CE PC P+ C++G TC L C C G+ G
Sbjct: 221 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCV 280
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C +G +C+D LD +TC C + WTG C+EDVDEC + C N C N+A
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPH-----CRNGGTCQNSA 335
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G + C C++GW G CE N+DDC C G+TCID V F C C G G C L+ D
Sbjct: 336 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DM 394
Query: 479 CAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDHC-----AGSPCGNGAACYTA 531
C +PC +C L + C+C G+SG C D D C SPC +G +C
Sbjct: 395 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 454
Query: 532 QSDYYCHCAPGWTGKNC 548
+ C C PG+TG C
Sbjct: 455 PGSFNCLCPPGYTGSRC 471
Score = 221 bits (539), Expect = 1e-56
Identities = 142/478 (29%), Positives = 195/478 (40%), Gaps = 60/478 (12%)
Query: 236 RGELCSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
RG LC P P G C S C C + G C Q + C + CQ+GG+C+
Sbjct: 23 RGLLCGSF-PEPCANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQNAQLCQNGGSCQ 80
Query: 293 NTAP-------------DQYFCRCAEGFSGVDCE-RVDNPCAPQPCA-HGTCSLAGTTRG 337
P + C C GF+G C+ ++++PC P C+ G C + + R
Sbjct: 81 ALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRP 140
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C+C GW G A+ PC++G C C C G+ G AC DV+EC
Sbjct: 141 -QCSCMPGWTGEQCQLRDFCSAN-PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECF 198
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLV 456
GPC +C+NT G + C C G G CE C + C +G TC +
Sbjct: 199 QDP------GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMP 252
Query: 457 DD---FH-CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
+ FH C C G+ G C ++ D+C C NGG C D L+ Y C+CP ++G +C +
Sbjct: 253 EKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSE 312
Query: 513 DRDHCA--GSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
D D C G P C NG C + ++C C GW G +C E + C
Sbjct: 313 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE--------------ENLDDC 358
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
CA G TC+ GS+ C + L
Sbjct: 359 IAATCAPGSTCIDRVGSFSCLCPPGRT-----GLLCHLEDMCLSQPCHGDAQCSTNPLTG 413
Query: 630 GWACGCREGRTGALCELSLDLC-----GSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C+ G +G C LD C G SPC +GG C+ G + C C G+TG C
Sbjct: 414 STLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRC 471
Score = 202 bits (493), Expect = 5e-51
Identities = 122/379 (32%), Positives = 160/379 (42%), Gaps = 42/379 (11%)
Query: 229 CDCRPGWRGELCSQ-----CQPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ GE C C P K G C+ C+C W G C Q ++C
Sbjct: 102 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS 160
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAHGTCSLAGTTRGF 338
+ PC +GG C T P Q C C GF G CER N C P PC GT S T F
Sbjct: 161 AN-PCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGT-SCHNTLGSF 217
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR--DHLDG--FTCECADGWTGPACAEDVD 394
C C G G C +G +C+ D C C G+ GP C + D
Sbjct: 218 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPD 277
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ----CLHGA 450
C C N C + Y+C C WTG DC +VD+C Q C +G
Sbjct: 278 NCVSHQ--------CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGG 329
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
TC + FHC C +G+ G +C ++DDC C G C+D + ++ C+CP G +G C
Sbjct: 330 TCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 389
Query: 511 EDDRDHCAGSPCGNGAACYT--AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
+ D C PC A C T C C PG++G C Q D C + +
Sbjct: 390 HLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ----DLDECLMAQQ---- 440
Query: 569 CAEGMCANGGTCVREEGSW 587
C +GG+C+ GS+
Sbjct: 441 -GPSPCEHGGSCLNTPGSF 458
Score = 202 bits (493), Expect = 5e-51
Identities = 124/405 (30%), Positives = 175/405 (43%), Gaps = 43/405 (10%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCE-KPVCKEGCHPTHGRC 223
CQ + +FC R H + C+PGW G+ C+ + C G C
Sbjct: 113 CQAKLEDPCPPSFCSKRGRC--HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVC 170
Query: 224 --DRPG-DCDCRPGWRGELC----SQCQPYPG-CKHGY-CNGS--SWDCTCDTNWGGILC 272
P C C PG+ G C ++C PG C G C+ + S+ C C G C
Sbjct: 171 LATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRC 230
Query: 273 DQDLNYCGTHEPCQHGGTCENTAPDQ----YFCRCAEGFSGVDCERVDNPCAPQPCAHG- 327
+ C C +GGTC+ P++ + C C GF G CE + C C +G
Sbjct: 231 ELRAGPCPPRG-CSNGGTCQ-LMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGG 288
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX-XASGP--CLHGASCRDHLDGFTCECADGW 384
TC T +TC C W G A GP C +G +C++ F C C GW
Sbjct: 289 TCQDGLDT--YTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW 346
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG 444
G +C E++D+C + C + C + G +SC C G TG C D C
Sbjct: 347 GGTSCEENLDDCIAAT--------CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLS 397
Query: 445 QCLHG-ATCID--LVDDFHCACAAGYAGRTCSLDVDDC-----APRPCTNGGECVDLLNA 496
Q HG A C L C C GY+G TC D+D+C P PC +GG C++ +
Sbjct: 398 QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 457
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
+ C+CP G++G+ CE D + C PC G+ C + ++C C P
Sbjct: 458 FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 502
Score = 194 bits (474), Expect = 1e-48
Identities = 135/473 (28%), Positives = 183/473 (38%), Gaps = 46/473 (9%)
Query: 227 GDCDCRPGWRGELCS---QCQPYPGCKHG-YCNG----------------SSWDCTCDTN 266
G C C PG+ GE C CQ C++G C S+ CTC
Sbjct: 48 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 107
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH 326
+ G C L C G C A + C C G++G C+ D C+ PC +
Sbjct: 108 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF-CSANPCVN 166
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS--GPCLHGASCRDHLDGFTCECADGW 384
G LA T C C G+ G GPC G SC + L F C C G
Sbjct: 167 GGVCLA-TYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ 225
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG 444
GP C C R + G G C ++T + C C G+ G CE N D+C
Sbjct: 226 EGPRCELRAGPCPPRGCSNG--GTCQLMPEKDSTF--HLCLCPPGFIGPGCEVNPDNCVS 281
Query: 445 -QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNAYRCI 500
QC +G TC D +D + C C + G CS DVD+C P C NGG C + ++ C+
Sbjct: 282 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 341
Query: 501 CPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C G+ GT+CE++ D C + C G+ C + C C PG TG C + C
Sbjct: 342 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC- 400
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
+C+ C+ + G + GG
Sbjct: 401 ---HGDAQCSTNPLTGSTLCLCQPG--------YSGPTCHQDLDECLMAQQGPSPCEHGG 449
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
+CL + P + C C G TG+ CE + C S PC G C+ + C C
Sbjct: 450 SCLNT--PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLC 500
Score = 114 bits (274), Expect = 2e-24
Identities = 83/297 (27%), Positives = 112/297 (37%), Gaps = 39/297 (13%)
Query: 408 PCVNAAACNNTAGGY-SCACLAGWTGRDCETNVDDCTGQ--CLHGATC------------ 452
PC N C + + G +C C G+ G C+ D C C +G +C
Sbjct: 33 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPS 91
Query: 453 --IDLVDDFHCACAAGYAGRTCSLDVDD-CAPRPCTNGGEC-VDLLNAYRCICPVGFSGT 508
L F C C G+ G C ++D C P C+ G C + +C C G++G
Sbjct: 92 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 151
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER 568
C+ RD C+ +PC NG C CHC PG+ G C RD C
Sbjct: 152 QCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE----RDVNECFQ------- 199
Query: 569 CAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC--LPSA 626
G C G +C GS++ + GGTC +P
Sbjct: 200 -DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSN----GGTCQLMPEK 254
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
C C G G CE++ D C S C+NGG C G + C C WTG C+
Sbjct: 255 DSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS 311
Score = 81.8 bits (193), Expect = 1e-14
Identities = 72/261 (27%), Positives = 94/261 (36%), Gaps = 42/261 (16%)
Query: 446 CLHGATCIDL-VDDFHCACAAGYAGRTCSLDVDDCA-PRPCTNGGECVDLLNA------- 496
C +G TC+ L + C CA G+ G TC D C + C NGG C LL A
Sbjct: 34 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 92
Query: 497 -------YRCICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDY-YCHCAPGWTGKN 547
+ C C GF+G C+ D C S C C+ S C C PGWTG+
Sbjct: 93 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQ 152
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXX 607
C R + C+ C NGG C+ ++ +
Sbjct: 153 CQLR---------------DFCSANPCVNGGVCL---ATYPQIQCHCPPGFEGHACERDV 194
Query: 608 XXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC----V 663
GT + L + C C G+ G CEL C C NGG C
Sbjct: 195 NECFQDPGPCPKGTSCHNTLG-SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 253
Query: 664 GGSGWWMCECVAGWTGETCAV 684
S + +C C G+ G C V
Sbjct: 254 KDSTFHLCLCPPGFIGPGCEV 274
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/223 (26%), Positives = 73/223 (32%), Gaps = 38/223 (17%)
Query: 481 PRPCTNGGECVDL-LNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTA------- 531
P PC NGG C+ L L C C GF G C+ D C + C NG +C
Sbjct: 31 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGL 89
Query: 532 -------QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREE 584
+ C C PG+TG+ C + + C C+ G C +
Sbjct: 90 PSSPSPLTPSFLCTCLPGFTGERCQAKL-------------EDPCPPSFCSKRGRC-HIQ 135
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
S R GG CL A P C C G G C
Sbjct: 136 ASGRPQCSCMPGWTGEQCQLRDFCSANPCVN---GGVCL--ATYPQIQCHCPPGFEGHAC 190
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
E ++ C PC G C G + C C G G C +R
Sbjct: 191 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 233
>AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform
II precursor variant protein.
Length = 441
Score = 234 bits (573), Expect = 1e-60
Identities = 118/313 (37%), Positives = 156/313 (49%), Gaps = 14/313 (4%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 60 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 117
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 118 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 176
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +GA C+D +DG++C C G+ G C +VDEC A PC N A C N
Sbjct: 177 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--------ASDPCKNEATCLN 228
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G Y+C C ++G +CE +D+C Q CL+GATC D + + C CA G+ G C L+
Sbjct: 229 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 288
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
D+CA +PC +GG CVD N Y C C GF+GT+CE C PC N A C + +Y
Sbjct: 289 DECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 348
Query: 536 YCHCAPGWTGKNC 548
CHC PG+TG C
Sbjct: 349 TCHCWPGYTGAQC 361
Score = 202 bits (492), Expect = 7e-51
Identities = 96/282 (34%), Positives = 137/282 (48%), Gaps = 15/282 (5%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 52 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 109
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 110 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 169
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 170 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 221
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 222 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 281
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC 548
+CE + D CA PC +G C ++ Y C+C G+TG +C
Sbjct: 282 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHC 323
Score = 195 bits (475), Expect = 7e-49
Identities = 92/279 (32%), Positives = 134/279 (48%), Gaps = 13/279 (4%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 118 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 175
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 176 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 234
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 235 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 286
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 287 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 346
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
Y C C G++G CE D + C +PC + C S+
Sbjct: 347 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE 385
Score = 189 bits (460), Expect = 5e-47
Identities = 119/388 (30%), Positives = 172/388 (44%), Gaps = 49/388 (12%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 67 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 118
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 119 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 178
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 179 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 235
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 236 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 294
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 295 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 347
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C +D+++C PC + GECV+L + E
Sbjct: 348 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL---------------SSEKQYGRIT 392
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGK 546
G P + Y S Y C C PG+TG+
Sbjct: 393 GLP---SSFSYHEASGYVCICQPGFTGE 417
Score = 188 bits (458), Expect = 9e-47
Identities = 101/307 (32%), Positives = 136/307 (44%), Gaps = 30/307 (9%)
Query: 360 SGPCLHGASCRDHLD--GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
S PC A+C + F C+C G++G C + C S C + C+
Sbjct: 101 SNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNS--------CQHGGICHQ 152
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C AG+ GR CE + D+C C +GA C D +D + C C GY GR C L+V
Sbjct: 153 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 212
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC N C++ + Y CICP +SG NCE + D C PC NGA C A Y+
Sbjct: 213 DECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 272
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C CAPG+ G +C ++ CA C +GG CV E +
Sbjct: 273 CDCAPGFLGDHCELN--------------TDECASQPCLHGGLCVDGENRY---SCNCTG 315
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ TC S + C C G TGA CE+ L+ C S+PC
Sbjct: 316 SGFTGTHCETLMPLCWSKPCHNNATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPC 373
Query: 657 RNGGRCV 663
++ G CV
Sbjct: 374 QSNGECV 380
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 61 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 114
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 115 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 174
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 175 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 234
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 235 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 280
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 281 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 334
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 335 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 363
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 52 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 111
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 112 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 154
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 155 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 211
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 212 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 250
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 233 bits (569), Expect = 3e-60
Identities = 131/381 (34%), Positives = 174/381 (45%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C +G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPNG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
ET VD+C + CLHGA+C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 ETEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 221 bits (541), Expect = 8e-57
Identities = 135/389 (34%), Positives = 175/389 (44%), Gaps = 36/389 (9%)
Query: 191 TPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQ 244
T G C P + C C G C P G C C PG++G C +C
Sbjct: 56 TESGGYTCGP-MEPRGCATQPCHHGALCVP-QGPDPNGFRCYCVPGFQGPRCELDIDECA 113
Query: 245 PYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFC 301
P C HG C + ++C C + G+ C+ +++ C + PC HG +C + + C
Sbjct: 114 SRP-CHHGATCRNLADRYECHCPLGYAGVTCETEVDECAS-APCLHGASCLDGV-GSFRC 170
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXXXXXXA 359
CA G+ G C+ + C QPCAHG TC GF C C G+ G A
Sbjct: 171 VCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCEREVLECA 228
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGALGPCV 410
S PC H ASC + L F C C G++G C D DEC+ GR + ++ AL V
Sbjct: 229 SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGV 288
Query: 411 NAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAA 465
AA A G+ C C G+ G DC VD+C + CL+G C DL + F C C
Sbjct: 289 QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G C
Sbjct: 349 GYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLA 408
Query: 526 AACY----TAQSDYYCHCAPGWTGKNCTQ 550
A C + Y CHC PG G C Q
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 212 bits (517), Expect = 6e-54
Identities = 118/364 (32%), Positives = 158/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPNGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCETEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHGASC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 205 bits (500), Expect = 7e-52
Identities = 131/415 (31%), Positives = 171/415 (41%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPNGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCETEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ A+C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 69.7 bits (163), Expect = 5e-11
Identities = 29/71 (40%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNC 548
C PG+ G C
Sbjct: 1119 RCPPGFGGPRC 1129
Score = 69.3 bits (162), Expect = 6e-11
Identities = 70/246 (28%), Positives = 88/246 (35%), Gaps = 45/246 (18%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGA 526
AG S CA PC G EC Y C P+ G CA PC +GA
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTC-GPMEPRG---------CATQPCHHGA 80
Query: 527 ACYTAQSD---YYCHCAPGWTGKNC----------------TQRAARDRKTC-------S 560
C D + C+C PG+ G C T R DR C
Sbjct: 81 LCVPQGPDPNGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG 140
Query: 561 VLVE-ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
V E E + CA C +G +C+ GS+R G
Sbjct: 141 VTCETEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH----G 196
Query: 620 GTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GTC L G+ C C G G CE + C S+PC + C+ G G + C C G++
Sbjct: 197 GTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS 254
Query: 679 GETCAV 684
GE C V
Sbjct: 255 GELCEV 260
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCEDD---RDHCAGSPCGNGAACYTAQS 533
G C D A +P G G A +A+S
Sbjct: 1125 GGPRCRWDGWAGGWAANAPWGYGGAEKSARS 1155
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 8/77 (10%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDC 435
G + C C G+ G C
Sbjct: 1113 DGRFECRCPPGFGGPRC 1129
Score = 56.8 bits (131), Expect = 4e-07
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLD 475
G+ G C D
Sbjct: 1121 PPGFGGPRCRWD 1132
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG 348
G+GG
Sbjct: 1122 PGFGG 1126
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 56.4 bits (130), Expect = 5e-07
Identities = 30/76 (39%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
Query: 377 TCECADGWTGPACAED 392
C C G+ GP C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C ++ C C W G C+ ++ C + PC G C +T PD F
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS-APCARG-RC-HTHPDGRF 1116
Query: 301 -CRCAEGFSGVDC 312
CRC GF G C
Sbjct: 1117 ECRCPPGFGGPRC 1129
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/52 (36%), Positives = 24/52 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+AC C G G CE +D C S+PC G G + C C G+ G C
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRC 1129
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELCSQCQPYPGCK 250
C PGW+G CE V + CH GRC D +C C PG+ G C + G
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCR----WDGWA 1135
Query: 251 HGYCNGSSW 259
G+ + W
Sbjct: 1136 GGWAANAPW 1144
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
Score = 35.1 bits (77), Expect = 1.3
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 11/76 (14%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQD 275
+C C +GG C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 228 bits (557), Expect = 9e-59
Identities = 129/381 (33%), Positives = 171/381 (44%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPTG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E VD+C + CLHG +C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 EMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 224 bits (548), Expect = 1e-57
Identities = 138/394 (35%), Positives = 180/394 (45%), Gaps = 44/394 (11%)
Query: 186 GHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS-- 241
G Y+C P + C P G C +G PT RC C PG++G C
Sbjct: 59 GGYTCGPMEPRGCATQPCHHGALC----VPQGPDPTGFRCY------CVPGFQGPRCELD 108
Query: 242 --QCQPYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
+C P C HG C + ++C C + G+ C+ +++ C + PC HGG+C +
Sbjct: 109 IDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLDGV- 165
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXX 354
+ C CA G+ G C+ + C QPCAHG TC GF C C G+ G
Sbjct: 166 GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCERE 223
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGA 405
AS PC H ASC + L F C C G++G C D DEC+ GR + ++ A
Sbjct: 224 VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 406 LGPCVNAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
L V AA A G+ C C G+ G DC VD+C + CL+G C DL + F
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQ 343
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
Query: 521 PCGNGAACY----TAQSDYYCHCAPGWTGKNCTQ 550
C A C + Y CHC PG G C Q
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 210 bits (512), Expect = 2e-53
Identities = 117/364 (32%), Positives = 157/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG SC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 202 bits (494), Expect = 4e-51
Identities = 130/415 (31%), Positives = 170/415 (40%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ +C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 108 bits (259), Expect = 1e-22
Identities = 55/157 (35%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDCETNV--DDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
G + C C G+ G C V +C+ CL G+ C +C+C G AG+ C +
Sbjct: 1113 DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV 1172
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C PC NGG C CIC FSG CE
Sbjct: 1173 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 90.2 bits (214), Expect = 3e-17
Identities = 47/148 (31%), Positives = 64/148 (43%), Gaps = 4/148 (2%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLDVD--DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
G+ G C L V +C+ C +G C A C C G +G C+ C +
Sbjct: 1121 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
PC NG C A C C ++G+ C
Sbjct: 1181 PCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRF 1116
Query: 377 TCECADGWTGPACAEDVD--ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
C C G+ GP C V ECS ++T C++ + C + +C+CL G G+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECS-LNVT------CLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C+ C CL+G TC C C A ++G+ C +
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 83.8 bits (198), Expect = 3e-15
Identities = 47/156 (30%), Positives = 59/156 (37%), Gaps = 13/156 (8%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
G+GG + CL G+ C C C +G G C C
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-- 1179
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC+N C G C C A ++G+ CE
Sbjct: 1180 ------NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.2 bits (189), Expect = 3e-14
Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 53/250 (21%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRC-----------------IC------PV 503
AG S CA PC G EC Y C +C P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 504 GF--------SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
GF G CE D D CA PC +GA C Y CHC G+ G
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG---------- 140
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
TC + V+E CA C +GG+C+ GS+R
Sbjct: 141 -VTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH- 195
Query: 616 XQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECV 674
GGTC L G+ C C G G CE + C S+PC + C+ G G + C C
Sbjct: 196 ---GGTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
Query: 675 AGWTGETCAV 684
G++GE C V
Sbjct: 251 PGYSGELCEV 260
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/102 (37%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C PG+ G C R K CS+ V C +G GG+
Sbjct: 1119 RCPPGFGGPRC--RLPVPSKECSLNV----TCLDGSPCEGGS 1154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCE---DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G C ++ C +G+ C C C G G+ C
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP-------- 1176
Query: 563 VEESERCAEGMCANGGTC 580
C C NGGTC
Sbjct: 1177 ------CEANPCLNGGTC 1188
Score = 68.9 bits (161), Expect = 8e-11
Identities = 47/152 (30%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQDL--NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
+C C +GG C + C + C G CE +P C C EG +G C+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN-CSCLEGLAGQRCQVPTL 1175
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
PC PC + GTC AG C C+ + G
Sbjct: 1176 PCEANPCLNGGTCRAAGGVS--ECICNARFSG 1205
Score = 58.0 bits (134), Expect = 2e-07
Identities = 47/142 (33%), Positives = 56/142 (39%), Gaps = 20/142 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELC------SQCQ 244
C PGW+G CE V + CH GRC D +C C PG+ G C +C
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139
Query: 245 PYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFC 301
C G C G S +C+C G C C + PC +GGTC A C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PCLNGGTC-RAAGGVSEC 1197
Query: 302 RCAEGFSGVDCERVDNPCAPQP 323
C FSG CE P P
Sbjct: 1198 ICNARFSGQFCEVAKGLPLPLP 1219
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 17/168 (10%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA SPC + AC + C C PGW G C V+ C CA
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPR-----------CEAHVDP---CHSAPCAR 1105
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G +G + G C + P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD-GSPCEGGS--PAANCSCL 1162
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
EG G C++ C ++PC NGG C G C C A ++G+ C V
Sbjct: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/56 (35%), Positives = 26/56 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+AC C G G CE +D C S+PC G G + C C G+ G C + V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPV 1133
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 228 bits (557), Expect = 9e-59
Identities = 129/381 (33%), Positives = 171/381 (44%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPTG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E VD+C + CLHG +C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 EMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 224 bits (548), Expect = 1e-57
Identities = 138/394 (35%), Positives = 180/394 (45%), Gaps = 44/394 (11%)
Query: 186 GHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS-- 241
G Y+C P + C P G C +G PT RC C PG++G C
Sbjct: 59 GGYTCGPMEPRGCATQPCHHGALC----VPQGPDPTGFRCY------CVPGFQGPRCELD 108
Query: 242 --QCQPYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
+C P C HG C + ++C C + G+ C+ +++ C + PC HGG+C +
Sbjct: 109 IDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLDGV- 165
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXX 354
+ C CA G+ G C+ + C QPCAHG TC GF C C G+ G
Sbjct: 166 GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCERE 223
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGA 405
AS PC H ASC + L F C C G++G C D DEC+ GR + ++ A
Sbjct: 224 VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 406 LGPCVNAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
L V AA A G+ C C G+ G DC VD+C + CL+G C DL + F
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQ 343
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
Query: 521 PCGNGAACY----TAQSDYYCHCAPGWTGKNCTQ 550
C A C + Y CHC PG G C Q
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 210 bits (512), Expect = 2e-53
Identities = 117/364 (32%), Positives = 157/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG SC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 202 bits (494), Expect = 4e-51
Identities = 130/415 (31%), Positives = 170/415 (40%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ +C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 108 bits (259), Expect = 1e-22
Identities = 55/157 (35%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDCETNV--DDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
G + C C G+ G C V +C+ CL G+ C +C+C G AG+ C +
Sbjct: 1113 DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV 1172
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C PC NGG C CIC FSG CE
Sbjct: 1173 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 90.2 bits (214), Expect = 3e-17
Identities = 47/148 (31%), Positives = 64/148 (43%), Gaps = 4/148 (2%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLDVD--DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
G+ G C L V +C+ C +G C A C C G +G C+ C +
Sbjct: 1121 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
PC NG C A C C ++G+ C
Sbjct: 1181 PCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRF 1116
Query: 377 TCECADGWTGPACAEDVD--ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
C C G+ GP C V ECS ++T C++ + C + +C+CL G G+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECS-LNVT------CLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C+ C CL+G TC C C A ++G+ C +
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 83.8 bits (198), Expect = 3e-15
Identities = 47/156 (30%), Positives = 59/156 (37%), Gaps = 13/156 (8%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
G+GG + CL G+ C C C +G G C C
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-- 1179
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC+N C G C C A ++G+ CE
Sbjct: 1180 ------NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.2 bits (189), Expect = 3e-14
Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 53/250 (21%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRC-----------------IC------PV 503
AG S CA PC G EC Y C +C P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 504 GF--------SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
GF G CE D D CA PC +GA C Y CHC G+ G
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG---------- 140
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
TC + V+E CA C +GG+C+ GS+R
Sbjct: 141 -VTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH- 195
Query: 616 XQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECV 674
GGTC L G+ C C G G CE + C S+PC + C+ G G + C C
Sbjct: 196 ---GGTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
Query: 675 AGWTGETCAV 684
G++GE C V
Sbjct: 251 PGYSGELCEV 260
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/102 (37%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C PG+ G C R K CS+ V C +G GG+
Sbjct: 1119 RCPPGFGGPRC--RLPVPSKECSLNV----TCLDGSPCEGGS 1154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCE---DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G C ++ C +G+ C C C G G+ C
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP-------- 1176
Query: 563 VEESERCAEGMCANGGTC 580
C C NGGTC
Sbjct: 1177 ------CEANPCLNGGTC 1188
Score = 68.9 bits (161), Expect = 8e-11
Identities = 47/152 (30%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQDL--NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
+C C +GG C + C + C G CE +P C C EG +G C+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN-CSCLEGLAGQRCQVPTL 1175
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
PC PC + GTC AG C C+ + G
Sbjct: 1176 PCEANPCLNGGTCRAAGGVS--ECICNARFSG 1205
Score = 58.0 bits (134), Expect = 2e-07
Identities = 47/142 (33%), Positives = 56/142 (39%), Gaps = 20/142 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELC------SQCQ 244
C PGW+G CE V + CH GRC D +C C PG+ G C +C
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139
Query: 245 PYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFC 301
C G C G S +C+C G C C + PC +GGTC A C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PCLNGGTC-RAAGGVSEC 1197
Query: 302 RCAEGFSGVDCERVDNPCAPQP 323
C FSG CE P P
Sbjct: 1198 ICNARFSGQFCEVAKGLPLPLP 1219
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 17/168 (10%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA SPC + AC + C C PGW G C V+ C CA
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPR-----------CEAHVDP---CHSAPCAR 1105
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G +G + G C + P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD-GSPCEGGS--PAANCSCL 1162
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
EG G C++ C ++PC NGG C G C C A ++G+ C V
Sbjct: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/56 (35%), Positives = 26/56 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+AC C G G CE +D C S+PC G G + C C G+ G C + V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPV 1133
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 228 bits (557), Expect = 9e-59
Identities = 129/381 (33%), Positives = 171/381 (44%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPTG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E VD+C + CLHG +C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 EMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 224 bits (548), Expect = 1e-57
Identities = 138/394 (35%), Positives = 180/394 (45%), Gaps = 44/394 (11%)
Query: 186 GHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS-- 241
G Y+C P + C P G C +G PT RC C PG++G C
Sbjct: 59 GGYTCGPMEPRGCATQPCHHGALC----VPQGPDPTGFRCY------CVPGFQGPRCELD 108
Query: 242 --QCQPYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
+C P C HG C + ++C C + G+ C+ +++ C + PC HGG+C +
Sbjct: 109 IDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLDGV- 165
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXX 354
+ C CA G+ G C+ + C QPCAHG TC GF C C G+ G
Sbjct: 166 GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCERE 223
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGA 405
AS PC H ASC + L F C C G++G C D DEC+ GR + ++ A
Sbjct: 224 VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 406 LGPCVNAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
L V AA A G+ C C G+ G DC VD+C + CL+G C DL + F
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQ 343
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
Query: 521 PCGNGAACY----TAQSDYYCHCAPGWTGKNCTQ 550
C A C + Y CHC PG G C Q
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 210 bits (512), Expect = 2e-53
Identities = 117/364 (32%), Positives = 157/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG SC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 202 bits (494), Expect = 4e-51
Identities = 130/415 (31%), Positives = 170/415 (40%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ +C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 80.2 bits (189), Expect = 3e-14
Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 53/250 (21%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRC-----------------IC------PV 503
AG S CA PC G EC Y C +C P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 504 GF--------SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
GF G CE D D CA PC +GA C Y CHC G+ G
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG---------- 140
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
TC + V+E CA C +GG+C+ GS+R
Sbjct: 141 -VTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH- 195
Query: 616 XQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECV 674
GGTC L G+ C C G G CE + C S+PC + C+ G G + C C
Sbjct: 196 ---GGTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
Query: 675 AGWTGETCAV 684
G++GE C V
Sbjct: 251 PGYSGELCEV 260
Score = 69.7 bits (163), Expect = 5e-11
Identities = 29/71 (40%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNC 548
C PG+ G C
Sbjct: 1119 RCPPGFGGPRC 1129
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCEDD---RDHCAGSPCGNGAACYTAQS 533
G C D A +P G G A +A+S
Sbjct: 1125 GGPRCRWDGWAGGWAANAPWGYGGAEKSARS 1155
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 8/77 (10%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDC 435
G + C C G+ G C
Sbjct: 1113 DGRFECRCPPGFGGPRC 1129
Score = 56.8 bits (131), Expect = 4e-07
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLD 475
G+ G C D
Sbjct: 1121 PPGFGGPRCRWD 1132
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG 348
G+GG
Sbjct: 1122 PGFGG 1126
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 56.4 bits (130), Expect = 5e-07
Identities = 30/76 (39%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
Query: 377 TCECADGWTGPACAED 392
C C G+ GP C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C ++ C C W G C+ ++ C + PC G C +T PD F
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS-APCARG-RC-HTHPDGRF 1116
Query: 301 -CRCAEGFSGVDC 312
CRC GF G C
Sbjct: 1117 ECRCPPGFGGPRC 1129
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/52 (36%), Positives = 24/52 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+AC C G G CE +D C S+PC G G + C C G+ G C
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRC 1129
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELCSQCQPYPGCK 250
C PGW+G CE V + CH GRC D +C C PG+ G C + G
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCR----WDGWA 1135
Query: 251 HGYCNGSSW 259
G+ + W
Sbjct: 1136 GGWAANAPW 1144
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
Score = 35.1 bits (77), Expect = 1.3
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 11/76 (14%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQD 275
+C C +GG C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 228 bits (557), Expect = 9e-59
Identities = 129/381 (33%), Positives = 171/381 (44%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPTG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E VD+C + CLHG +C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 EMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 224 bits (548), Expect = 1e-57
Identities = 138/394 (35%), Positives = 180/394 (45%), Gaps = 44/394 (11%)
Query: 186 GHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS-- 241
G Y+C P + C P G C +G PT RC C PG++G C
Sbjct: 59 GGYTCGPMEPRGCATQPCHHGALC----VPQGPDPTGFRCY------CVPGFQGPRCELD 108
Query: 242 --QCQPYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
+C P C HG C + ++C C + G+ C+ +++ C + PC HGG+C +
Sbjct: 109 IDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLDGV- 165
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXX 354
+ C CA G+ G C+ + C QPCAHG TC GF C C G+ G
Sbjct: 166 GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCERE 223
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGA 405
AS PC H ASC + L F C C G++G C D DEC+ GR + ++ A
Sbjct: 224 VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 406 LGPCVNAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
L V AA A G+ C C G+ G DC VD+C + CL+G C DL + F
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQ 343
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
Query: 521 PCGNGAACY----TAQSDYYCHCAPGWTGKNCTQ 550
C A C + Y CHC PG G C Q
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 210 bits (512), Expect = 2e-53
Identities = 117/364 (32%), Positives = 157/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG SC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 202 bits (494), Expect = 4e-51
Identities = 130/415 (31%), Positives = 170/415 (40%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ +C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 108 bits (259), Expect = 1e-22
Identities = 55/157 (35%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDCETNV--DDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
G + C C G+ G C V +C+ CL G+ C +C+C G AG+ C +
Sbjct: 1113 DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV 1172
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C PC NGG C CIC FSG CE
Sbjct: 1173 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 90.2 bits (214), Expect = 3e-17
Identities = 47/148 (31%), Positives = 64/148 (43%), Gaps = 4/148 (2%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLDVD--DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
G+ G C L V +C+ C +G C A C C G +G C+ C +
Sbjct: 1121 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
PC NG C A C C ++G+ C
Sbjct: 1181 PCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRF 1116
Query: 377 TCECADGWTGPACAEDVD--ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
C C G+ GP C V ECS ++T C++ + C + +C+CL G G+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECS-LNVT------CLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C+ C CL+G TC C C A ++G+ C +
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 83.8 bits (198), Expect = 3e-15
Identities = 47/156 (30%), Positives = 59/156 (37%), Gaps = 13/156 (8%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
G+GG + CL G+ C C C +G G C C
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-- 1179
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC+N C G C C A ++G+ CE
Sbjct: 1180 ------NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.2 bits (189), Expect = 3e-14
Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 53/250 (21%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRC-----------------IC------PV 503
AG S CA PC G EC Y C +C P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 504 GF--------SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
GF G CE D D CA PC +GA C Y CHC G+ G
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG---------- 140
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
TC + V+E CA C +GG+C+ GS+R
Sbjct: 141 -VTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH- 195
Query: 616 XQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECV 674
GGTC L G+ C C G G CE + C S+PC + C+ G G + C C
Sbjct: 196 ---GGTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
Query: 675 AGWTGETCAV 684
G++GE C V
Sbjct: 251 PGYSGELCEV 260
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/102 (37%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C PG+ G C R K CS+ V C +G GG+
Sbjct: 1119 RCPPGFGGPRC--RLPVPSKECSLNV----TCLDGSPCEGGS 1154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCE---DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G C ++ C +G+ C C C G G+ C
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP-------- 1176
Query: 563 VEESERCAEGMCANGGTC 580
C C NGGTC
Sbjct: 1177 ------CEANPCLNGGTC 1188
Score = 68.9 bits (161), Expect = 8e-11
Identities = 47/152 (30%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQDL--NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
+C C +GG C + C + C G CE +P C C EG +G C+
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN-CSCLEGLAGQRCQVPTL 1175
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
PC PC + GTC AG C C+ + G
Sbjct: 1176 PCEANPCLNGGTCRAAGGVS--ECICNARFSG 1205
Score = 58.0 bits (134), Expect = 2e-07
Identities = 47/142 (33%), Positives = 56/142 (39%), Gaps = 20/142 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELC------SQCQ 244
C PGW+G CE V + CH GRC D +C C PG+ G C +C
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139
Query: 245 PYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFC 301
C G C G S +C+C G C C + PC +GGTC A C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PCLNGGTC-RAAGGVSEC 1197
Query: 302 RCAEGFSGVDCERVDNPCAPQP 323
C FSG CE P P
Sbjct: 1198 ICNARFSGQFCEVAKGLPLPLP 1219
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 17/168 (10%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA SPC + AC + C C PGW G C V+ C CA
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPR-----------CEAHVDP---CHSAPCAR 1105
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G +G + G C + P C C
Sbjct: 1106 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD-GSPCEGGS--PAANCSCL 1162
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
EG G C++ C ++PC NGG C G C C A ++G+ C V
Sbjct: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/56 (35%), Positives = 26/56 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+AC C G G CE +D C S+PC G G + C C G+ G C + V
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPV 1133
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 228 bits (557), Expect = 9e-59
Identities = 129/381 (33%), Positives = 171/381 (44%), Gaps = 36/381 (9%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH---LDG 375
CA PCA GT A + G+TC G A+ PC HGA C G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----------CATQPCHHGALCVPQGPDPTG 91
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F C C G+ GP C D+DEC+ R PC + A C N A Y C C G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASR--------PCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E VD+C + CLHG +C+D V F C CA GY G C LD+D+C +PC +GG C DL+
Sbjct: 144 EMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 495 NAYRCICP-VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
N +RC C G+ GT+CE + CA +PC + A+C + C C PG++G+ C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV--- 260
Query: 554 RDRKTC-SVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXX 610
D C S + RC + GG G++
Sbjct: 261 -DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 611 XXXXXXQA----GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
GG C LP G+ C C +G G CE +D C S PC +GG C
Sbjct: 320 EVDECASRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV 377
Query: 667 GWWMCECVAGWTGETCAVRVS 687
++C C W G C+V+++
Sbjct: 378 AGYICRCPETWGGRDCSVQLT 398
Score = 224 bits (548), Expect = 1e-57
Identities = 138/394 (35%), Positives = 180/394 (45%), Gaps = 44/394 (11%)
Query: 186 GHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS-- 241
G Y+C P + C P G C +G PT RC C PG++G C
Sbjct: 59 GGYTCGPMEPRGCATQPCHHGALC----VPQGPDPTGFRCY------CVPGFQGPRCELD 108
Query: 242 --QCQPYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
+C P C HG C + ++C C + G+ C+ +++ C + PC HGG+C +
Sbjct: 109 IDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLDGV- 165
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTC-DRGWGGXXXXXX 354
+ C CA G+ G C+ + C QPCAHG TC GF C C G+ G
Sbjct: 166 GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH--DLVNGFRCDCAGTGYEGTHCERE 223
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-------GRSM--TEGA 405
AS PC H ASC + L F C C G++G C D DEC+ GR + ++ A
Sbjct: 224 VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 406 LGPCVNAAACN----NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
L V AA A G+ C C G+ G DC VD+C + CL+G C DL + F
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQ 343
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C GYAG TC DVD+C PC +GG C D + Y C CP + G +C C G
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
Query: 521 PCGNGAACY----TAQSDYYCHCAPGWTGKNCTQ 550
C A C + Y CHC PG G C Q
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
Score = 210 bits (512), Expect = 2e-53
Identities = 117/364 (32%), Positives = 157/364 (43%), Gaps = 54/364 (14%)
Query: 244 QPYPGCKHGYCNGSSWDCTCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQ--YF 300
+P C C + +C T GG C + C T +PC HG C PD +
Sbjct: 37 EPPSACASDPCAPGT-ECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFR 93
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C GF G CE + CA +PC HG TC + C C G+ G A
Sbjct: 94 CYCVPGFQGPRCELDIDECASRPCHHGATCR--NLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG SC D + F C CA G+ G C D+DEC + PC + C++
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ--------PCAHGGTCHDLV 203
Query: 420 GGYSCACLA-GWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+ C C G+ G CE V +C + C H A+C++ + F C C GY+G C +D D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 478 DCAPRPCTNGGECVDLLN---------------------AYRCICPVGFSGTNCEDDRDH 516
+CA PC +GG C+ + + C CP GF G +C + D
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA PC NG C + + CHC G+ G C E+ + C C +
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE--------------EDVDECLSDPCLH 369
Query: 577 GGTC 580
GGTC
Sbjct: 370 GGTC 373
Score = 202 bits (494), Expect = 4e-51
Identities = 130/415 (31%), Positives = 170/415 (40%), Gaps = 39/415 (9%)
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT-CSLAGTT-RGFTC 340
+PC G C+ T Y C E CA QPC HG C G GF C
Sbjct: 45 DPCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C G+ G AS PC HGA+CR+ D + C C G+ G C +VDEC
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---- 150
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDF 459
A PC++ +C + G + C C G+ G C+ ++D+C Q C HG TC DLV+ F
Sbjct: 151 ----ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 460 HCACAA-GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
C CA GY G C +V +CA PC + C++ L ++RC+C G+SG CE D D CA
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 519 GSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVE------ESERCAE 571
SPC +G C Y + G + AA C E E + CA
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
C NGG C ++ + GGTC S G+
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH----GGTC--SDTVAGY 380
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETC 682
C C E G C + L C C C+ G ++C C G G C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 19/202 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCR--PGWRGELCSQCQPYPGCKHGYCN 255
C PG+ G+ CE V ++ C C G C R P G + + +PG + +
Sbjct: 249 CWPGYSGELCE--VDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAA---FPGA-FSFRH 300
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ + C C + G C +++ C + PC +GG C++ P+ + C C +G++G CE
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASR-PCLNGGHCQDL-PNGFQCHCPDGYAGPTCEED 358
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC----R 370
+ C PC HG TCS T G+ C C WGG C A+C
Sbjct: 359 VDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
Query: 371 DHLDGFTCECADGWTGPACAED 392
+ + C C G GP C ++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 80.2 bits (189), Expect = 3e-14
Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 53/250 (21%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGEC-VDLLNAYRC-----------------IC------PV 503
AG S CA PC G EC Y C +C P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 504 GF--------SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
GF G CE D D CA PC +GA C Y CHC G+ G
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAG---------- 140
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
TC + V+E CA C +GG+C+ GS+R
Sbjct: 141 -VTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH- 195
Query: 616 XQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECV 674
GGTC L G+ C C G G CE + C S+PC + C+ G G + C C
Sbjct: 196 ---GGTC--HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
Query: 675 AGWTGETCAV 684
G++GE C V
Sbjct: 251 PGYSGELCEV 260
Score = 69.7 bits (163), Expect = 5e-11
Identities = 29/71 (40%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 538 HCAPGWTGKNC 548
C PG+ G C
Sbjct: 1119 RCPPGFGGPRC 1129
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 506 SGTNCEDD---RDHCAGSPCGNGAACYTAQS 533
G C D A +P G G A +A+S
Sbjct: 1125 GGPRCRWDGWAGGWAANAPWGYGGAEKSARS 1155
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 8/77 (10%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 1112
Query: 419 AGGYSCACLAGWTGRDC 435
G + C C G+ G C
Sbjct: 1113 DGRFECRCPPGFGGPRC 1129
Score = 56.8 bits (131), Expect = 4e-07
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 1061 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 1120
Query: 464 AAGYAGRTCSLD 475
G+ G C D
Sbjct: 1121 PPGFGGPRCRWD 1132
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 1121
Query: 344 RGWGG 348
G+GG
Sbjct: 1122 PGFGG 1126
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 537 C 537
C
Sbjct: 868 C 868
Score = 56.4 bits (130), Expect = 5e-07
Identities = 30/76 (39%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 1060 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
Query: 377 TCECADGWTGPACAED 392
C C G+ GP C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 759 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 814
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 815 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 870 AEATFREGPPAAFSGHNASSGR 891
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C ++ C C W G C+ ++ C + PC G C +T PD F
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS-APCARG-RC-HTHPDGRF 1116
Query: 301 -CRCAEGFSGVDC 312
CRC GF G C
Sbjct: 1117 ECRCPPGFGGPRC 1129
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/52 (36%), Positives = 24/52 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+AC C G G CE +D C S+PC G G + C C G+ G C
Sbjct: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRC 1129
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 865
Query: 422 YSCACLA 428
+ C A
Sbjct: 866 FVCVAEA 872
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 867
Query: 301 C 301
C
Sbjct: 868 C 868
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELCSQCQPYPGCK 250
C PGW+G CE V + CH GRC D +C C PG+ G C + G
Sbjct: 1082 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCR----WDGWA 1135
Query: 251 HGYCNGSSW 259
G+ + W
Sbjct: 1136 GGWAANAPW 1144
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 1020 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 1079
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 1080 CACGPGWEGPRCEAHV 1095
Score = 35.1 bits (77), Expect = 1.3
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 11/76 (14%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
Query: 260 DCTCDTNWGGILCDQD 275
+C C +GG C D
Sbjct: 1117 ECRCPPGFGGPRCRWD 1132
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADD 1339
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1151 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1207
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1208 GVNCEVDI 1215
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 150 bits (363), Expect = 3e-35
Identities = 68/197 (34%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNC 548
+ + C C + G+ C
Sbjct: 1316 LNKFQCLCDVAFAGERC 1332
Score = 139 bits (337), Expect = 4e-32
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 10/204 (4%)
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTT 335
LN C ++ PC HGG CE+ Y C C G+SG CE + C PC HG CS
Sbjct: 1140 LNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS--DRV 1195
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED--V 393
+ CTC+ G+ G S C +GA+C H +G++C C +TG C +
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATC 452
G T C N C C C G+TG CE ++D+C C++G C
Sbjct: 1256 STVCGNEKTNLT---CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC 1312
Query: 453 IDLVDDFHCACAAGYAGRTCSLDV 476
DL++ F C C +AG C +DV
Sbjct: 1313 QDLLNKFQCLCDVAFAGERCEVDV 1336
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 120 bits (288), Expect = 3e-26
Identities = 68/220 (30%), Positives = 91/220 (41%), Gaps = 20/220 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+D C S PC NGG C + C C + GE C V VS
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVS 1337
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 107 bits (256), Expect = 3e-22
Identities = 61/207 (29%), Positives = 91/207 (43%), Gaps = 23/207 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNV 439
C + + C C + G CE +V
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDV 1336
Score = 92.3 bits (219), Expect = 8e-18
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C C G+ G AS PC++G C+D L+ F C C + G C DV
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSSL 1339
Query: 397 S 397
S
Sbjct: 1340 S 1340
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADD 1339
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1151 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1207
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1208 GVNCEVDI 1215
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADD 1339
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1151 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1207
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1208 GVNCEVDI 1215
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADD 1339
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1151 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1207
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1208 GVNCEVDI 1215
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 227 bits (555), Expect = 2e-58
Identities = 138/443 (31%), Positives = 200/443 (45%), Gaps = 59/443 (13%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKHG-YCNGSSWD--CTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+HG C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQDGI-DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
C + G S PCL+GA+C+D L + C+CA G+ G C + DEC+ +
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ- 269
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACL-AGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD 458
PC++ C + YSC C +G+TG CET + C + C + ATC D VD+
Sbjct: 270 -------PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL--------------------LNAYR 498
+ C C GY G C +D+++C PC + GECV+L + Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CIC GF+G +CE+D + C+ +PC NG C +Y CHC + + T RD
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FDNLSRTFYGGRD--- 437
Query: 559 CSVLVEESERCAEGMCANGGTCV 581
CS ++ C C N GTC+
Sbjct: 438 CSDIL---LGCTHQQCLNNGTCI 457
Score = 225 bits (551), Expect = 5e-58
Identities = 128/413 (30%), Positives = 182/413 (44%), Gaps = 27/413 (6%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSG 507
+ ATC++ + + C C Y+G C L++D+C +PC NG C D L AY C C GF G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC-APGWTGKNC-TQRAARDRKTCSVLVEE 565
+CE + D CA PC +G C ++ Y C+C G+TG +C T K C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC----HN 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG-TCLP 624
+ C + + + TC G + Q G T LP
Sbjct: 313 NATCEDSV--DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Query: 625 SAL----PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
S+ G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Score = 216 bits (527), Expect = 4e-55
Identities = 125/419 (29%), Positives = 178/419 (42%), Gaps = 51/419 (12%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C ++G C ++DEC + PC+N A C + G Y C C G+ G CE
Sbjct: 210 CICPHNYSGVNCELEIDECWSQ--------PCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACA-AGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N D+C Q CLHG C+D + + C C +G+ G C + C +PC N C D ++
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC--------------------YTAQSDY 535
Y C C G++G CE D + C +PC + C Y S Y
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C PG+TG +C E+ C+ C NGGTC G++
Sbjct: 382 VCICQPGFTGIHCE--------------EDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 596 XXXXXDSXXXXXXXXXXXXXXQA--GGTCLPSAL--PPGWACGCREGRTGALCELSLDL 650
Q GTC+P G++C C G TG+LCE++ L
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 178 bits (434), Expect = 7e-44
Identities = 117/396 (29%), Positives = 168/396 (42%), Gaps = 58/396 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG 248
C PG+ G CE + C + G C + C C G+ G C +C P
Sbjct: 98 CPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP- 156
Query: 249 CKHG-YCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
C++G C + C C + G CD +++ C + +PC++ TC N +Y C C
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS-DPCKNEATCLNEI-GRYTCICPH 214
Query: 306 GFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+SGV+CE + C QPC +G TC A + C C G+ G AS PCL
Sbjct: 215 NYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS 423
HG C D + ++C C G+TG C + C + PC N A C ++ Y+
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK--------PCHNNATCEDSVDNYT 324
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------FH------CA 462
C C G+TG CE ++++C C C++L + +H C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSGTNCEDDRDH 516
C G+ G C DV++C+ PC NGG C +L Y C CP + G +C D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 517 CAGSPCGNGAAC----YTAQSDYYCHCAPGWTGKNC 548
C C N C Q + C C G+TG C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 167 bits (406), Expect = 2e-40
Identities = 99/329 (30%), Positives = 132/329 (40%), Gaps = 30/329 (9%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S C + ++C+D C C+D T +D D + PC +A C NT
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSN----PCQGSATCVNTP 89
Query: 420 G--GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
G + C C G++G CET + C C HG C C C AGYAGR C +D
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D+CA PC NG C D ++ Y C C G+ G +C+ + D CA PC N A C Y
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C ++G NC E + C C NG TC G++
Sbjct: 210 CICPHNYSGVNCEL--------------EIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR-EGRTGALCELSLDLCGSSP 655
+ GG C+ ++C C G TG CE + LC S P
Sbjct: 256 GDHCELNTDECASQPCLH----GGLCVDGE--NRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C N C + C C G+TG C +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1176 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1226
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 150 bits (363), Expect = 3e-35
Identities = 68/197 (34%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1195
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 532 QSDYYCHCAPGWTGKNC 548
+ + C C + G+ C
Sbjct: 1316 LNKFQCLCDVAFAGERC 1332
Score = 139 bits (337), Expect = 4e-32
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 10/204 (4%)
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTT 335
LN C ++ PC HGG CE+ Y C C G+SG CE + C PC HG CS
Sbjct: 1140 LNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS--DRV 1195
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED--V 393
+ CTC+ G+ G S C +GA+C H +G++C C +TG C +
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATC 452
G T C N C C C G+TG CE ++D+C C++G C
Sbjct: 1256 STVCGNEKTNLT---CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC 1312
Query: 453 IDLVDDFHCACAAGYAGRTCSLDV 476
DL++ F C C +AG C +DV
Sbjct: 1313 QDLLNKFQCLCDVAFAGERCEVDV 1336
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1205
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1311
Query: 580 C 580
C
Sbjct: 1312 C 1312
Score = 120 bits (288), Expect = 3e-26
Identities = 68/220 (30%), Positives = 91/220 (41%), Gaps = 20/220 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1239
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1297
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+D C S PC NGG C + C C + GE C V VS
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVS 1337
Score = 107 bits (256), Expect = 3e-22
Identities = 125/479 (26%), Positives = 175/479 (36%), Gaps = 64/479 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN-----A 412
AS PC +GA C+D +DG++C C G+ G C +VDEC+ A C+N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT--CLNEIGRYT 209
Query: 413 AACNNTAGGYSCA----------CLAGWTGRDC-ETNVDDCTGQCLHGATCIDLVDDFHC 461
C + G +C CL G T +D DC L G C +L D C
Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL-GDHC-ELNTD-EC 266
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGG----ECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
A G C +D ++ CT G C L+ C + CED D+
Sbjct: 267 ASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPL--CWSKPCHNNATCEDSVDNY 323
Query: 517 -CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C P GA C ++ C+ P + C + ++ + + S E A
Sbjct: 324 TCHCWPGYTGAQCEIDLNE--CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE---A 378
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+G C+ + G + Q GGTC LP + C C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-------------QNGGTC--ENLPGNYTCHC 423
Query: 636 ---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECVAGWTGETCAV 684
RT G C L C C N G C+ G + C C +G+TG C +
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 107 bits (256), Expect = 3e-22
Identities = 61/207 (29%), Positives = 91/207 (43%), Gaps = 23/207 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1199
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1309
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNV 439
C + + C C + G CE +V
Sbjct: 1310 GLCQDLLNKFQCLCDVAFAGERCEVDV 1336
Score = 92.3 bits (219), Expect = 8e-18
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1222 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C C G+ G AS PC++G C+D L+ F C C + G C DV
Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSSL 1339
Query: 397 S 397
S
Sbjct: 1340 S 1340
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/219 (21%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+D C S PC+N C+ G + C C ++G C + +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 506 SG 507
+G
Sbjct: 955 NG 956
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 942
Query: 532 QSDYYC 537
+ C
Sbjct: 943 LQGFEC 948
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1193 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1305
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1306 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1333
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 876 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 943
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 944 QGFECIANAVFNGQ 957
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 889 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 944
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 945 GFECIANAVFNG 956
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 714
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 213 bits (521), Expect = 2e-54
Identities = 137/475 (28%), Positives = 193/475 (40%), Gaps = 45/475 (9%)
Query: 225 RPGDCDCRPGWRGELCSQCQPYPGCKHG-------YCNGSSWDCTCDTNWGGILCDQDLN 277
R D R G G S C C +G S+ C+C + + G C D+N
Sbjct: 123 RIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVN 182
Query: 278 YCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTR 336
C + +PCQ+GGTC + + + C+C GF G CE +PC + C H G C + +
Sbjct: 183 ECAS-QPCQNGGTCTH-GINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSA 240
Query: 337 GFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C C G+ G + PCL+G SC D + +TC CA+ + G C E
Sbjct: 241 --VCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-----ET 293
Query: 397 SGRSMTEGAL-GPCVNAAACNNTAGGYSCACLAGWTGRDCETNV-DDCTGQCLHGATCID 454
+ + L PC N C + GY C C G+ G DC V DDC +C +G C+
Sbjct: 294 GDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC--ECRNGGRCLG 351
Query: 455 LVDDFHCACAAGYAGRTCSLDVD--DC-APRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+ C C G+ G C ++ C C +GG C++ +Y C+C + ++
Sbjct: 352 -ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSL 410
Query: 512 DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
C PC NG +C Y C C G+ GK+C + AR C+
Sbjct: 411 P--SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEK--AR-----------PHLCSS 455
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
G C NGGTC G + + GGTC +
Sbjct: 456 GPCRNGGTCKEAGGEYHCSCPYRFTGRHCE---IGKPDSCASGPCHNGGTCFHYI--GKY 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G +G CE++ C SPC NGG C + C C AG+ G C V
Sbjct: 511 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV 565
Score = 191 bits (466), Expect = 9e-48
Identities = 129/429 (30%), Positives = 168/429 (39%), Gaps = 47/429 (10%)
Query: 272 CDQDLNYCGTHEPCQHGGTCEN---TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT 328
C + C PC +GG C + T Y C C GF+G C N CA QPC +G
Sbjct: 134 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 193
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
G F C C G+GG + C HG C+ C C G+TG A
Sbjct: 194 TCTHGIN-SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 252
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETN----VDDC-T 443
C DVD+CS PC+N +C + G Y+C C + G CET D C +
Sbjct: 253 CEMDVDDCSP--------DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 304
Query: 444 GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV-DDCAPRPCTNGGECVDLLNAYRCICP 502
C +G TC+D + C C G+ G C V DDC C NGG C+ N C CP
Sbjct: 305 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGA-NTTLCQCP 360
Query: 503 VGFSGTNCEDDRDH--C-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+GF G CE + C + C +G C Y C C T N +
Sbjct: 361 LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSP---- 413
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
C C NGG+C + S+ + + G
Sbjct: 414 ---------CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC---RNG 461
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GTC + + C C TG CE+ D C S PC NGG C G + C+C G++
Sbjct: 462 GTCKEAG--GEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 519
Query: 679 GETCAVRVS 687
G C + S
Sbjct: 520 GRHCEIAPS 528
Score = 187 bits (455), Expect = 2e-46
Identities = 117/378 (30%), Positives = 159/378 (42%), Gaps = 30/378 (7%)
Query: 198 CLPGWQGDNCEKPVCKEGCH-----PTHGRCDRPGD---CDCRPGWRGE--LCSQCQPYP 247
C G+ G CE + C+ P G C G C C L S C P
Sbjct: 359 CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDP 418
Query: 248 GCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
G C+ S+ C C + G C++ + + PC++GGTC+ A +Y C C
Sbjct: 419 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKE-AGGEYHCSCPY 477
Query: 306 GFSGVDCERVDNP--CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
F+G CE + P CA PC +G + + C C G+ G PC
Sbjct: 478 RFTGRHCE-IGKPDSCASGPCHNGGTCFHYIGK-YKCDCPPGFSGRHCEIAPSPCFRSPC 535
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL---GPCVNAAACNNTAG 420
++G +C D F C C G+ G C +VD + L G + A A
Sbjct: 536 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDR 595
Query: 421 GYS---------CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
GYS C W+ +D+C Q CLHG +C D V + C C+ GY G
Sbjct: 596 GYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGA 655
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C L+ D+C PC NGG C +L AY C CP GF G +CE + D C SPC +G C +
Sbjct: 656 HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 715
Query: 531 AQSDYYCHCAPGWTGKNC 548
Y C C + G +C
Sbjct: 716 GGGAYLCVCPESFFGYHC 733
Score = 186 bits (454), Expect = 3e-46
Identities = 128/436 (29%), Positives = 176/436 (40%), Gaps = 45/436 (10%)
Query: 229 CDCRPGWRGELC----SQCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C G+ G C ++C P G C +S+ C C +GG C+ + C T
Sbjct: 166 CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK 225
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
E CQHGG C+ C C G++G CE + C+P PC +G S +TC C
Sbjct: 226 E-CQHGGQCQ-VENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGG-SCVDLVGNYTCLC 282
Query: 343 DRGWGGXXXXXXXX----XXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV-DECS 397
+ G S PC +G +C D G+ CEC +G+ G C E V D+C
Sbjct: 283 AEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE 342
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R+ LG N C G + C T C N QC G C++
Sbjct: 343 CRNGGR-CLG--ANTTLCQCPLGFFGLLCEFEITAMPCNMNT-----QCPDGGYCMEHGG 394
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH- 516
+ C C + + SL C PC NGG C ++Y C CP GF G +CE R H
Sbjct: 395 SYLCVCHTDH-NASHSLP-SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL 452
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C+ PC NG C A +Y+C C +TG++C + + + CA G C N
Sbjct: 453 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCE-------------IGKPDSCASGPCHN 499
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
GGTC G ++ + GGTC + C C+
Sbjct: 500 GGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVN----GGTC--EDRDTDFFCHCQ 553
Query: 637 EGRTGALCELSLDLCG 652
G G C+ +D CG
Sbjct: 554 AGYMGRRCQAEVD-CG 568
Score = 186 bits (453), Expect = 3e-46
Identities = 124/417 (29%), Positives = 169/417 (40%), Gaps = 57/417 (13%)
Query: 186 GHYSC---TPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGEL 239
G Y C T H LP C+ C G G CD D C+C G+ G+
Sbjct: 394 GSYLCVCHTDHNASHSLPS----PCDSDPCFNG-----GSCDAHDDSYTCECPRGFHGKH 444
Query: 240 CSQCQPYPGCKHGYCN--------GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C + +P+ C G C G + C+C + G C+ PC +GGTC
Sbjct: 445 CEKARPHL-CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 503
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXX 350
+ +Y C C GFSG CE +PC PC +G TC T F C C G+ G
Sbjct: 504 FHYI-GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTD--FFCHCQAGYMGRR 560
Query: 351 XXXXXXXXASGPCLH----------GASCRDHLD-GFT---------CECADGWTGPACA 390
H GA D G++ C+ W+ P
Sbjct: 561 CQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC 620
Query: 391 EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHG 449
++DEC + PC++ +C + GY C C G+ G CE D+C C +G
Sbjct: 621 LEIDECRSQ--------PCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNG 672
Query: 450 ATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN 509
+C +L + C C AG+ G C +VD C PC +GG C AY C+CP F G +
Sbjct: 673 GSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYH 732
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
CE D C SPCG C + + C C G+TG++C + VEES
Sbjct: 733 CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEES 789
Score = 182 bits (444), Expect = 4e-45
Identities = 147/533 (27%), Positives = 205/533 (38%), Gaps = 65/533 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG-CHPTHGRC---DRPGDCDCRPGWRGE 238
D G+Y+C L GD+ C CH G C D+ C+C G+ G
Sbjct: 273 DLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCH-NGGTCVDADQGYVCECPEGFMGL 331
Query: 239 LCSQCQPYP-GCKHG-YCNGSSWD-CTCDTNWGGILCDQDLNY--CGTHEPCQHGGTCEN 293
C + P C++G C G++ C C + G+LC+ ++ C + C GG C
Sbjct: 332 DCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCME 391
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXX 353
Y C C + + +PC PC +G S +TC C RG+ G
Sbjct: 392 HG-GSYLCVCHTDHNA--SHSLPSPCDSDPCFNGG-SCDAHDDSYTCECPRGFHGKHCEK 447
Query: 354 XXXXX-ASGPCLHGASCRDHLDGFTCECADGWTGPACA-EDVDECSGRSMTEGALGPCVN 411
+SGPC +G +C++ + C C +TG C D C A GPC N
Sbjct: 448 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC--------ASGPCHN 499
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGR 470
C + G Y C C G++GR CE C C++G TC D DF C C AGY GR
Sbjct: 500 GGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGR 559
Query: 471 TCSLDVDDCAPRPCTNG-----GECVDLLNAYRCICPVGFSGTN----CED--------- 512
C +VD P + G + + Y C S + C+
Sbjct: 560 RCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQ 619
Query: 513 --DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
+ D C PC +G +C + Y C C+ G+ G +C E + C
Sbjct: 620 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL--------------ERDECR 665
Query: 571 EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPG 630
C NGG+C G++ ++ Q GG C
Sbjct: 666 AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPC----QHGGRCESGG--GA 719
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C E G CE D C SSPC G C+ +G C C G+TGE CA
Sbjct: 720 YLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 772
Score = 178 bits (433), Expect = 9e-44
Identities = 155/558 (27%), Positives = 211/558 (37%), Gaps = 70/558 (12%)
Query: 165 CQPNYYNTTCTTFCRPRDDK---FGHYSCTPDGDKHCL--PGWQGDNCEKPVCKEGCHP- 218
C + TC T P D K G +G C+ G+ G CE V + C P
Sbjct: 206 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDV--DDCSPD 263
Query: 219 ---THGRC-DRPGD--CDCRPGWRGELCSQCQ-PYP-GCKHGYC-NGSS-------WDCT 262
G C D G+ C C ++G C P P C C NG + + C
Sbjct: 264 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE 323
Query: 263 CDTNWGGILCDQDL-NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER--VDNPC 319
C + G+ C + + + C C++GG C + C+C GF G+ CE PC
Sbjct: 324 CPEGFMGLDCRERVPDDC----ECRNGGRC--LGANTTLCQCPLGFFGLLCEFEITAMPC 377
Query: 320 APQP-CAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
C G C G + + C C S PC +G SC H D +T
Sbjct: 378 NMNTQCPDGGYCMEHGGS--YLCVCHTDHNASHSLPSPCD--SDPCFNGGSCDAHDDSYT 433
Query: 378 CECADGWTGPACAEDVDE-CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
CEC G+ G C + CS GPC N C G Y C+C +TGR CE
Sbjct: 434 CECPRGFHGKHCEKARPHLCSS--------GPCRNGGTCKEAGGEYHCSCPYRFTGRHCE 485
Query: 437 TNV-DDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
D C +G C +G TC + + C C G++GR C + C PC NGG C D
Sbjct: 486 IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRD 545
Query: 495 NAYRCICPVGFSGTNCEDDRD--------HCAGSPCGN--GAACYTAQSDYYCHCAPGWT 544
+ C C G+ G C+ + D H G GA A Y AP
Sbjct: 546 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 605
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
+ C + ++E C C +GG+C + +
Sbjct: 606 -RVCQPHGVWSEPPQCLEIDE---CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE--- 658
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
+ GG+C LP + C C G G CE +D C SSPC++GGRC
Sbjct: 659 -LERDECRAHPCRNGGSC--RNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 715
Query: 665 GSGWWMCECVAGWTGETC 682
G G ++C C + G C
Sbjct: 716 GGGAYLCVCPESFFGYHC 733
Score = 176 bits (429), Expect = 3e-43
Identities = 119/403 (29%), Positives = 164/403 (40%), Gaps = 49/403 (12%)
Query: 198 CLPGWQGDNCEKPV-------CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP---YP 247
CL G+ G C V C+ G THG C C G+ G C Q
Sbjct: 168 CLSGFTGRRCHLDVNECASQPCQNGGTCTHGI--NSFRCQCPAGFGGPTCETAQSPCDTK 225
Query: 248 GCKHG-YC---NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C+HG C NGS+ C C + G C+ D++ C +PC +GG+C + + Y C C
Sbjct: 226 ECQHGGQCQVENGSAV-CVCQAGYTGAACEMDVDDCSP-DPCLNGGSCVDLVGN-YTCLC 282
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTT----RGFTCTCDRGWGGXXXXXXXXXXA 359
AE F G+ CE D+P P C C GT +G+ C C G+ G
Sbjct: 283 AEPFKGLRCETGDHP-VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC 341
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G C + C+C G+ G C ++ T+ C + C
Sbjct: 342 E--CRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ-----CPDGGYCMEHG 393
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD- 478
G Y C C + D + C +G +C D + C C G+ G+ C
Sbjct: 394 GSYLCVCHTDHNASHSLPSPCD-SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL 452
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-DHCAGSPCGNGAACYTAQSDYYC 537
C+ PC NGG C + Y C CP F+G +CE + D CA PC NG C+ Y C
Sbjct: 453 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKC 512
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
C PG++G++C + S C C NGGTC
Sbjct: 513 DCPPGFSGRHCE-------------IAPSP-CFRSPCVNGGTC 541
Score = 174 bits (424), Expect = 1e-42
Identities = 139/459 (30%), Positives = 185/459 (40%), Gaps = 73/459 (15%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
LC + C T P D C G C+ QG CE C EG R
Sbjct: 281 LCAEPFKGLRCETGDHPVPDACLSAPCHNGGT--CVDADQGYVCE---CPEGFMGLDCRE 335
Query: 224 DRPGDCDCRPGWR----------------GELCS------QCQPYPGCKH-GYC--NGSS 258
P DC+CR G R G LC C C GYC +G S
Sbjct: 336 RVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGS 395
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV-DN 317
+ C C T+ L +PC +GG+C+ D Y C C GF G CE+ +
Sbjct: 396 YLCVCHTDHN---ASHSLPSPCDSDPCFNGGSCD-AHDDSYTCECPRGFHGKHCEKARPH 451
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
C+ PC + GTC AG + C+C R G ASGPC +G +C ++
Sbjct: 452 LCSSGPCRNGGTCKEAGGE--YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK 509
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C+C G++G C C RS PCVN C + + C C AG+ GR C
Sbjct: 510 YKCDCPPGFSGRHCEIAPSPCF-RS-------PCVNGGTCEDRDTDFFCHCQAGYMGRRC 561
Query: 436 ETNVDDCTGQCLHGATC----IDLVDDFHCACAAGYA------GRTCS-----------L 474
+ VD + + AT L AC GY+ R C L
Sbjct: 562 QAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCL 621
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
++D+C +PC +GG C D + Y C+C G+ G +CE +RD C PC NG +C
Sbjct: 622 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGA 681
Query: 535 YYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEG 572
Y C C G+ G +C T+ A D C + RC G
Sbjct: 682 YVCRCPAGFVGVHCETEVDACDSSPC----QHGGRCESG 716
Score = 62.5 bits (145), Expect = 7e-09
Identities = 29/68 (42%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG+C G+ C C G GA CEL D C + PCRNGG C G ++C C AG+
Sbjct: 634 GGSCQDRVA--GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 691
Query: 679 GETCAVRV 686
G C V
Sbjct: 692 GVHCETEV 699
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/52 (28%), Positives = 26/52 (50%)
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+C+ +PC NG C + C C PG+ G+ C + + C+ L E++
Sbjct: 1179 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETK 1230
Score = 43.2 bits (97), Expect = 0.005
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+C+ PC NGG CV +A+ C C GF G CE
Sbjct: 1179 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1212
Score = 40.7 bits (91), Expect = 0.025
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C +PC+NGG CV G+ C+C G+ G C
Sbjct: 1180 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1211
Score = 39.5 bits (88), Expect = 0.058
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE----RVDNPC 319
+ PCQ+GGTC A D + C C GF G CE +V PC
Sbjct: 1181 SENPCQNGGTCVPGA-DAHSCDCGPGFKGRRCELACIKVSRPC 1222
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C +G TC+ D C C G+ GR C L + RPCT
Sbjct: 1185 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPCT 1223
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 8/68 (11%)
Query: 627 LPPGWACGCREG--RTGALCELSLDLC-GSSPCRNGGR----CVGGSGWWMCECVAGWTG 679
+P WA + R G C + +C PC NGG+ CV G+ + C C++G+TG
Sbjct: 116 VPGRWAFRIDDAQVRVGG-CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTG 174
Query: 680 ETCAVRVS 687
C + V+
Sbjct: 175 RRCHLDVN 182
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC N C A +SC C G+ GR CE
Sbjct: 1184 PCQNGGTCVPGADAHSCDCGPGFKGRRCE 1212
>BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF
repeat containing protein.
Length = 737
Score = 212 bits (518), Expect = 5e-54
Identities = 106/300 (35%), Positives = 151/300 (50%), Gaps = 23/300 (7%)
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC----ENTAPDQYFCRCAEGFSGVDC 312
+++ CTC+ + G C++ + C +PCQ+ +C E + C C G++G C
Sbjct: 332 ATFSCTCEEQYVGTFCEE-YDAC-QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELC 389
Query: 313 ERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+ + C PC +G ++ + GFTC C G+ G AS PC + +C +
Sbjct: 390 QSKIDYCILDPCRNGATCISSLS-GFTCQCPEGYFGSACEEKVDLCASSPCQNNGTC--Y 446
Query: 373 LDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DG FTC C+ G+TGP CA+ +D C AL PC + C + Y C C G+
Sbjct: 447 VDGVHFTCNCSPGFTGPTCAQLIDFC--------ALSPCAHGT-CRSVGTSYKCLCDPGY 497
Query: 431 TGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
G CE ++C + CL+ ATC DLV+ + C C A Y G C L D CA C NG
Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 557
Query: 490 C-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C D LN CIC GF+G C+ D + C +PC +G +C + Y CHC GW G NC
Sbjct: 558 CDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 205 bits (500), Expect = 7e-52
Identities = 112/326 (34%), Positives = 154/326 (47%), Gaps = 27/326 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---CQPYPGCKHGYC 254
C+PG N + K C T + C C + G C + CQ P + C
Sbjct: 307 CVPGESHANDLECSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASC 364
Query: 255 -------NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
+GS++ C C + G LC ++YC +PC++G TC ++ + C+C EG+
Sbjct: 365 IDANEKQDGSNFTCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSG-FTCQCPEGY 422
Query: 308 SGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G CE + CA PC + GTC + G FTC C G+ G A PC HG
Sbjct: 423 FGSACEEKVDLCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPCAHG 480
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+CR + C C G+ G C E+ +EC PC+NAA C + GY C C
Sbjct: 481 -TCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVC 531
Query: 427 LAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
LA + G CE D C CL+GATC + C CA G+ G C +D+++C PC
Sbjct: 532 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCH 591
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCE 511
+GG C+D N Y C CP G+ G NCE
Sbjct: 592 HGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 186 bits (452), Expect = 5e-46
Identities = 94/270 (34%), Positives = 124/270 (45%), Gaps = 16/270 (5%)
Query: 285 CQHGGTCENTAPDQYF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR----GFT 339
C G C + F C C E + G CE D C +PC + + + FT
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C G+ G PC +GA+C L GFTC+C +G+ G AC E VD C
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLC--- 434
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD 458
A PC N C ++C C G+TG C +D C C HG TC +
Sbjct: 435 -----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTS 488
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C + ++C PC N C DL+N Y C+C + GT+CE +D CA
Sbjct: 489 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 548
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C NGA C + + C CAPG+TG+ C
Sbjct: 549 NVSCLNGATCDSDGLNGTCICAPGFTGEEC 578
Score = 172 bits (419), Expect = 5e-42
Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 22/280 (7%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPG-DCDCRPGWRGELCSQCQPY---PGCKHGY-CNGS 257
D C++ C+ C + + D C C PG+ GELC Y C++G C S
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS 410
Query: 258 --SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ C C + G C++ ++ C + PCQ+ GTC + C C+ GF+G C ++
Sbjct: 411 LSGFTCQCPEGYFGSACEEKVDLCAS-SPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
+ CA PCAHGTC GT+ + C CD G+ G S PCL+ A+CRD ++G
Sbjct: 469 IDFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG 526
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C C + G C D C+ S C+N A C++ +C C G+TG +C
Sbjct: 527 YECVCLAEYKGTHCELYKDPCANVS--------CLNGATCDSDGLNGTCICAPGFTGEEC 578
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ ++++C + C HG +C+D + ++C C G+ G C +
Sbjct: 579 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 163 bits (397), Expect = 2e-39
Identities = 95/313 (30%), Positives = 130/313 (41%), Gaps = 28/313 (8%)
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F+C C + + G C E+ D C + A C++A ++C CL G+TG C
Sbjct: 334 FSCTCEEQYVGTFC-EEYDACQRKPCQNNA--SCIDANE-KQDGSNFTCVCLPGYTGELC 389
Query: 436 ETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC-VDL 493
++ +D C C +GATCI + F C C GY G C VD CA PC N G C VD
Sbjct: 390 QSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDG 449
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
++ + C C GF+G C D CA SPC +G C + + Y C C PG+ G C
Sbjct: 450 VH-FTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDPGYHGLYCE---- 503
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
EE C C N TC + +
Sbjct: 504 ----------EEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G TC L C C G TG C++ ++ C S+PC +GG C+ + C C
Sbjct: 554 N----GATCDSDGL--NGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 607
Query: 674 VAGWTGETCAVRV 686
GW G C + +
Sbjct: 608 PHGWVGANCEIHL 620
Score = 155 bits (375), Expect = 1e-36
Identities = 100/329 (30%), Positives = 138/329 (41%), Gaps = 38/329 (11%)
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDG--FTCECA 381
G C+ + F+CTC+ + G PC + ASC D DG FTC C
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRK-PCQNNASCIDANEKQDGSNFTCVCL 381
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
G+TG C +D C L PC N A C ++ G++C C G+ G CE VD
Sbjct: 382 PGYTGELCQSKIDYC--------ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDL 433
Query: 442 CTGQ-CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + TC +D V F C C+ G+ G TC+ +D CA PC +G C + +Y+C
Sbjct: 434 CASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKC 491
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 492 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-------- 543
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ CA C NG TC + + D G
Sbjct: 544 ------KDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD----IDINECDSNPCHHG 593
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSL 648
G+CL P G+ C C G GA CE+ L
Sbjct: 594 GSCLDQ--PNGYNCHCPHGWVGANCEIHL 620
Score = 136 bits (329), Expect = 4e-31
Identities = 83/272 (30%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD-----DFHCACAAGYAGRTCSLD 475
+SC C + G CE D C + C + A+CID + +F C C GY G C
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+D C PC NG C+ L+ + C CP G+ G+ CE+ D CA SPC N CY +
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDGVHF 452
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C+C+PG+TG C Q C++ CA G C + GT S++
Sbjct: 453 TCNCSPGFTGPTCAQLI----DFCAL-----SPCAHGTCRSVGT------SYKCLCDPGY 497
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ TC L G+ C C G CEL D C +
Sbjct: 498 HGLYCEEEYNECLSAPCLNAA----TCRD--LVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C C C G+TGE C + ++
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDIN 583
Score = 129 bits (312), Expect = 4e-29
Identities = 89/312 (28%), Positives = 131/312 (41%), Gaps = 42/312 (13%)
Query: 165 CQPNYYNTTCTTF--CRPRDDKFGHYSCTPDGDKH--------CLPGWQGDNCEKPV--- 211
C+ Y T C + C+ + + + SC +K CLPG+ G+ C+ +
Sbjct: 338 CEEQYVGTFCEEYDACQRKPCQ-NNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYC 396
Query: 212 ----CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ----CQPYPGCKHGYC--NGSSWDC 261
C+ G C C G+ G C + C P +G C +G + C
Sbjct: 397 ILDPCRNGATCISSLSGFT--CQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDGVHFTC 454
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
C + G C Q +++C PC HG TC + Y C C G+ G+ CE N C
Sbjct: 455 NCSPGFTGPTCAQLIDFCAL-SPCAHG-TCRSVGTS-YKCLCDPGYHGLYCEEEYNECLS 511
Query: 322 QPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC-RDHLDGFTCE 379
PC + TC G+ C C + G A+ CL+GA+C D L+G TC
Sbjct: 512 APCLNAATCR--DLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCI 568
Query: 380 CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV 439
CA G+TG C D++EC PC + +C + GY+C C GW G +CE ++
Sbjct: 569 CAPGFTGEECDIDINECDSN--------PCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Query: 440 DDCTGQCLHGAT 451
+G T
Sbjct: 621 QWKSGHMAESLT 632
Score = 68.9 bits (161), Expect = 8e-11
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 24/181 (13%)
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+ C H C C T S+ + C C + G C + A RK C +
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC----QN 360
Query: 566 SERCAEGMCANGG---TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C + G TCV G D + G TC
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC-------------RNGATC 407
Query: 623 LPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ S G+ C C EG G+ CE +DLC SSPC+N G C + C C G+TG TC
Sbjct: 408 ISSL--SGFTCQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 465
Query: 683 A 683
A
Sbjct: 466 A 466
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/87 (39%), Positives = 42/87 (48%), Gaps = 15/87 (17%)
Query: 479 CAPRPCTNGGECVDLLN------------AYRCICPVGFSGTNCEDDRDHCAGSPC--GN 524
CA +PC NGG C Y C CP G SG NC+ D CA +PC GN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 525 GAACYTAQSD-YYCHCAPGWTGKNCTQ 550
++ ++ SD Y C C G+ G NC Q
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 62.5 bits (145), Expect = 7e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 283 EPCQHGGTCENTA-PDQ----------YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSL 331
+PC++GG C + PD Y C C G SG +C+ V +PCA PC HG CS
Sbjct: 51 QPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSS 110
Query: 332 AGTTR--GFTCTCDRGWGG 348
+ ++ G+ C C+ G+ G
Sbjct: 111 SSSSSSDGYLCICNEGYEG 129
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 226 PGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS-SWDCTCDTNWGGILCDQDLNYCGTHEP 284
PG C +P G +C+ +P P +H G + CTC G C + C ++ P
Sbjct: 45 PGPCAAQPCRNGGVCTS-RPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN-P 102
Query: 285 CQHGG--TCENTAPDQYFCRCAEGFSGVDCER 314
C HG + +++ D Y C C EG+ G +CE+
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 318 PCAPQPCAHG-TCSL-----------AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
PCA QPC +G C+ AG G++CTC G G AS PC H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 366 G---ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G +S DG+ C C +G+ GP C + + TE
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTE 146
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNG---GECVDLLNAYRCICPVGFSGTNCE 511
+ C C AG +G C L D CA PC +G + Y CIC G+ G NCE
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNG---GRCVGGSGWWMCECVAGWTGETC 682
PG++C C G +GA C+L D C S+PC +G S ++C C G+ G C
Sbjct: 76 PGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 46.0 bits (104), Expect = 7e-04
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS-----GWWMCECV 674
G C ++C C E G CE D C PC+N C+ + + C C+
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 381
Query: 675 AGWTGETCAVRV 686
G+TGE C ++
Sbjct: 382 PGYTGELCQSKI 393
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHG---ATCIDLVDDFHCACAAGYAGRTC 472
GYSC C AG +G +C+ D C + C HG ++ D + C C GY G C
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 37.9 bits (84), Expect = 0.18
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 5/62 (8%)
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
G++C C G +G C D C+ G C +++ ++++ GY C C G+ G +
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGN---C--SSSSSSSSDGYLCICNEGYEGPN 131
Query: 435 CE 436
CE
Sbjct: 132 CE 133
>BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein.
Length = 454
Score = 212 bits (517), Expect = 6e-54
Identities = 106/300 (35%), Positives = 151/300 (50%), Gaps = 23/300 (7%)
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC----ENTAPDQYFCRCAEGFSGVDC 312
+++ CTC+ + G C++ + C +PCQ+ +C E + C C G++G C
Sbjct: 49 ATFSCTCEEQYVGTFCEE-YDAC-QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELC 106
Query: 313 ERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+ + C PC +G ++ + GFTC C G+ G AS PC + +C +
Sbjct: 107 QSKIDYCILDPCRNGATCISSLS-GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTC--Y 163
Query: 373 LDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DG FTC C+ G+TGP CA+ +D C AL PC + C + Y C C G+
Sbjct: 164 VDGVHFTCNCSPGFTGPTCAQLIDFC--------ALSPCAHGT-CRSVGTSYKCLCDPGY 214
Query: 431 TGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
G CE ++C + CL+ ATC DLV+ + C C A Y G C L D CA C NG
Sbjct: 215 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 274
Query: 490 C-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C D LN CIC GF+G C+ D + C +PC +G +C + Y CHC GW G NC
Sbjct: 275 CDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 333
Score = 209 bits (510), Expect = 4e-53
Identities = 113/326 (34%), Positives = 155/326 (47%), Gaps = 27/326 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---CQPYPGCKHGYC 254
C+PG N + K C T + C C + G C + CQ P + C
Sbjct: 24 CVPGESHANDLECSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASC 81
Query: 255 -------NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
+GS++ C C + G LC ++YC +PC++G TC ++ + C+C EG+
Sbjct: 82 IDANEKQDGSNFTCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSG-FTCQCPEGY 139
Query: 308 SGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G CE +PCA PC + GTC + G FTC C G+ G A PC HG
Sbjct: 140 FGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPCAHG 197
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+CR + C C G+ G C E+ +EC PC+NAA C + GY C C
Sbjct: 198 -TCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVC 248
Query: 427 LAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
LA + G CE D C CL+GATC + C CA G+ G C +D+++C PC
Sbjct: 249 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCH 308
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCE 511
+GG C+D N Y C CP G+ G NCE
Sbjct: 309 HGGSCLDQPNGYNCHCPHGWVGANCE 334
Score = 186 bits (454), Expect = 3e-46
Identities = 94/270 (34%), Positives = 124/270 (45%), Gaps = 16/270 (5%)
Query: 285 CQHGGTCENTAPDQYF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR----GFT 339
C G C + F C C E + G CE D C +PC + + + FT
Sbjct: 36 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFT 94
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C G+ G PC +GA+C L GFTC+C +G+ G AC E VD C
Sbjct: 95 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC--- 151
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD 458
A PC N C ++C C G+TG C +D C C HG TC +
Sbjct: 152 -----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTS 205
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C + ++C PC N C DL+N Y C+C + GT+CE +D CA
Sbjct: 206 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 265
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C NGA C + + C CAPG+TG+ C
Sbjct: 266 NVSCLNGATCDSDGLNGTCICAPGFTGEEC 295
Score = 171 bits (417), Expect = 8e-42
Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 22/280 (7%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPG-DCDCRPGWRGELCSQCQPY---PGCKHGY-CNGS 257
D C++ C+ C + + D C C PG+ GELC Y C++G C S
Sbjct: 68 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS 127
Query: 258 --SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ C C + G C++ ++ C + PCQ+ GTC + C C+ GF+G C ++
Sbjct: 128 LSGFTCQCPEGYFGSACEEKVDPCAS-SPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 185
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
+ CA PCAHGTC GT+ + C CD G+ G S PCL+ A+CRD ++G
Sbjct: 186 IDFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG 243
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C C + G C D C+ S C+N A C++ +C C G+TG +C
Sbjct: 244 YECVCLAEYKGTHCELYKDPCANVS--------CLNGATCDSDGLNGTCICAPGFTGEEC 295
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ ++++C + C HG +C+D + ++C C G+ G C +
Sbjct: 296 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 335
Score = 165 bits (400), Expect = 9e-40
Identities = 95/313 (30%), Positives = 130/313 (41%), Gaps = 28/313 (8%)
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F+C C + + G C E+ D C + A C++A ++C CL G+TG C
Sbjct: 51 FSCTCEEQYVGTFC-EEYDACQRKPCQNNA--SCIDANE-KQDGSNFTCVCLPGYTGELC 106
Query: 436 ETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC-VDL 493
++ +D C C +GATCI + F C C GY G C VD CA PC N G C VD
Sbjct: 107 QSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDG 166
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
++ + C C GF+G C D CA SPC +G C + + Y C C PG+ G C
Sbjct: 167 VH-FTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDPGYHGLYCE---- 220
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
EE C C N TC + +
Sbjct: 221 ----------EEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 270
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G TC L C C G TG C++ ++ C S+PC +GG C+ + C C
Sbjct: 271 N----GATCDSDGL--NGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 324
Query: 674 VAGWTGETCAVRV 686
GW G C + +
Sbjct: 325 PHGWVGANCEIHL 337
Score = 156 bits (378), Expect = 4e-37
Identities = 100/329 (30%), Positives = 138/329 (41%), Gaps = 38/329 (11%)
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDG--FTCECA 381
G C+ + F+CTC+ + G PC + ASC D DG FTC C
Sbjct: 40 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRK-PCQNNASCIDANEKQDGSNFTCVCL 98
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
G+TG C +D C L PC N A C ++ G++C C G+ G CE VD
Sbjct: 99 PGYTGELCQSKIDYC--------ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDP 150
Query: 442 CTGQ-CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + TC +D V F C C+ G+ G TC+ +D CA PC +G C + +Y+C
Sbjct: 151 CASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKC 208
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 209 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-------- 260
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ CA C NG TC + + D G
Sbjct: 261 ------KDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD----IDINECDSNPCHHG 310
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSL 648
G+CL P G+ C C G GA CE+ L
Sbjct: 311 GSCLDQ--PNGYNCHCPHGWVGANCEIHL 337
Score = 136 bits (330), Expect = 3e-31
Identities = 83/272 (30%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD-----DFHCACAAGYAGRTCSLD 475
+SC C + G CE D C + C + A+CID + +F C C GY G C
Sbjct: 51 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 109
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+D C PC NG C+ L+ + C CP G+ G+ CE+ D CA SPC N CY +
Sbjct: 110 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 169
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C+C+PG+TG C Q C++ CA G C + GT S++
Sbjct: 170 TCNCSPGFTGPTCAQLI----DFCAL-----SPCAHGTCRSVGT------SYKCLCDPGY 214
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ TC L G+ C C G CEL D C +
Sbjct: 215 HGLYCEEEYNECLSAPCLNAA----TCRD--LVNGYECVCLAEYKGTHCELYKDPCANVS 268
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C C C G+TGE C + ++
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFTGEECDIDIN 300
Score = 129 bits (312), Expect = 4e-29
Identities = 89/312 (28%), Positives = 131/312 (41%), Gaps = 42/312 (13%)
Query: 165 CQPNYYNTTCTTF--CRPRDDKFGHYSCTPDGDKH--------CLPGWQGDNCEKPV--- 211
C+ Y T C + C+ + + + SC +K CLPG+ G+ C+ +
Sbjct: 55 CEEQYVGTFCEEYDACQRKPCQ-NNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYC 113
Query: 212 ----CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ----CQPYPGCKHGYC--NGSSWDC 261
C+ G C C G+ G C + C P +G C +G + C
Sbjct: 114 ILDPCRNGATCISSLSGFT--CQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTC 171
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
C + G C Q +++C PC HG TC + Y C C G+ G+ CE N C
Sbjct: 172 NCSPGFTGPTCAQLIDFCAL-SPCAHG-TCRSVGTS-YKCLCDPGYHGLYCEEEYNECLS 228
Query: 322 QPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC-RDHLDGFTCE 379
PC + TC G+ C C + G A+ CL+GA+C D L+G TC
Sbjct: 229 APCLNAATCR--DLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCI 285
Query: 380 CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV 439
CA G+TG C D++EC PC + +C + GY+C C GW G +CE ++
Sbjct: 286 CAPGFTGEECDIDINECDSN--------PCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 337
Query: 440 DDCTGQCLHGAT 451
+G T
Sbjct: 338 QWKSGHMAESLT 349
Score = 66.1 bits (154), Expect = 6e-10
Identities = 50/181 (27%), Positives = 66/181 (36%), Gaps = 24/181 (13%)
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+ C H C C T S+ + C C + G C + A RK C +
Sbjct: 22 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC----QN 77
Query: 566 SERCAEGMCANGG---TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C + G TCV G D + G TC
Sbjct: 78 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC-------------RNGATC 124
Query: 623 LPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ S G+ C C EG G+ CE +D C SSPC+N G C + C C G+TG TC
Sbjct: 125 ISSL--SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 182
Query: 683 A 683
A
Sbjct: 183 A 183
Score = 46.0 bits (104), Expect = 7e-04
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS-----GWWMCECV 674
G C ++C C E G CE D C PC+N C+ + + C C+
Sbjct: 40 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 98
Query: 675 AGWTGETCAVRV 686
G+TGE C ++
Sbjct: 99 PGYTGELCQSKI 110
>AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein.
Length = 737
Score = 212 bits (517), Expect = 6e-54
Identities = 106/300 (35%), Positives = 151/300 (50%), Gaps = 23/300 (7%)
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC----ENTAPDQYFCRCAEGFSGVDC 312
+++ CTC+ + G C++ + C +PCQ+ +C E + C C G++G C
Sbjct: 332 ATFSCTCEEQYVGTFCEE-YDAC-QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELC 389
Query: 313 ERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+ + C PC +G ++ + GFTC C G+ G AS PC + +C +
Sbjct: 390 QSKIDYCILDPCRNGATCISSLS-GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTC--Y 446
Query: 373 LDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DG FTC C+ G+TGP CA+ +D C AL PC + C + Y C C G+
Sbjct: 447 VDGVHFTCNCSPGFTGPTCAQLIDFC--------ALSPCAHGT-CRSVGTSYKCLCDPGY 497
Query: 431 TGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
G CE ++C + CL+ ATC DLV+ + C C A Y G C L D CA C NG
Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 557
Query: 490 C-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C D LN CIC GF+G C+ D + C +PC +G +C + Y CHC GW G NC
Sbjct: 558 CDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 209 bits (510), Expect = 4e-53
Identities = 113/326 (34%), Positives = 155/326 (47%), Gaps = 27/326 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---CQPYPGCKHGYC 254
C+PG N + K C T + C C + G C + CQ P + C
Sbjct: 307 CVPGESHANDLECSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASC 364
Query: 255 -------NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
+GS++ C C + G LC ++YC +PC++G TC ++ + C+C EG+
Sbjct: 365 IDANEKQDGSNFTCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSG-FTCQCPEGY 422
Query: 308 SGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G CE +PCA PC + GTC + G FTC C G+ G A PC HG
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPCAHG 480
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+CR + C C G+ G C E+ +EC PC+NAA C + GY C C
Sbjct: 481 -TCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVC 531
Query: 427 LAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
LA + G CE D C CL+GATC + C CA G+ G C +D+++C PC
Sbjct: 532 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCH 591
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCE 511
+GG C+D N Y C CP G+ G NCE
Sbjct: 592 HGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 186 bits (454), Expect = 3e-46
Identities = 94/270 (34%), Positives = 124/270 (45%), Gaps = 16/270 (5%)
Query: 285 CQHGGTCENTAPDQYF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR----GFT 339
C G C + F C C E + G CE D C +PC + + + FT
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C G+ G PC +GA+C L GFTC+C +G+ G AC E VD C
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC--- 434
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD 458
A PC N C ++C C G+TG C +D C C HG TC +
Sbjct: 435 -----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTS 488
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C + ++C PC N C DL+N Y C+C + GT+CE +D CA
Sbjct: 489 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 548
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C NGA C + + C CAPG+TG+ C
Sbjct: 549 NVSCLNGATCDSDGLNGTCICAPGFTGEEC 578
Score = 171 bits (417), Expect = 8e-42
Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 22/280 (7%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPG-DCDCRPGWRGELCSQCQPY---PGCKHGY-CNGS 257
D C++ C+ C + + D C C PG+ GELC Y C++G C S
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS 410
Query: 258 --SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ C C + G C++ ++ C + PCQ+ GTC + C C+ GF+G C ++
Sbjct: 411 LSGFTCQCPEGYFGSACEEKVDPCAS-SPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
+ CA PCAHGTC GT+ + C CD G+ G S PCL+ A+CRD ++G
Sbjct: 469 IDFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG 526
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C C + G C D C+ S C+N A C++ +C C G+TG +C
Sbjct: 527 YECVCLAEYKGTHCELYKDPCANVS--------CLNGATCDSDGLNGTCICAPGFTGEEC 578
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ ++++C + C HG +C+D + ++C C G+ G C +
Sbjct: 579 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 165 bits (400), Expect = 9e-40
Identities = 95/313 (30%), Positives = 130/313 (41%), Gaps = 28/313 (8%)
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F+C C + + G C E+ D C + A C++A ++C CL G+TG C
Sbjct: 334 FSCTCEEQYVGTFC-EEYDACQRKPCQNNA--SCIDANE-KQDGSNFTCVCLPGYTGELC 389
Query: 436 ETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC-VDL 493
++ +D C C +GATCI + F C C GY G C VD CA PC N G C VD
Sbjct: 390 QSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDG 449
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
++ + C C GF+G C D CA SPC +G C + + Y C C PG+ G C
Sbjct: 450 VH-FTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDPGYHGLYCE---- 503
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
EE C C N TC + +
Sbjct: 504 ----------EEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G TC L C C G TG C++ ++ C S+PC +GG C+ + C C
Sbjct: 554 N----GATCDSDGL--NGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 607
Query: 674 VAGWTGETCAVRV 686
GW G C + +
Sbjct: 608 PHGWVGANCEIHL 620
Score = 156 bits (378), Expect = 4e-37
Identities = 100/329 (30%), Positives = 138/329 (41%), Gaps = 38/329 (11%)
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDG--FTCECA 381
G C+ + F+CTC+ + G PC + ASC D DG FTC C
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRK-PCQNNASCIDANEKQDGSNFTCVCL 381
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
G+TG C +D C L PC N A C ++ G++C C G+ G CE VD
Sbjct: 382 PGYTGELCQSKIDYC--------ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDP 433
Query: 442 CTGQ-CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + TC +D V F C C+ G+ G TC+ +D CA PC +G C + +Y+C
Sbjct: 434 CASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKC 491
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 492 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-------- 543
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ CA C NG TC + + D G
Sbjct: 544 ------KDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD----IDINECDSNPCHHG 593
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSL 648
G+CL P G+ C C G GA CE+ L
Sbjct: 594 GSCLDQ--PNGYNCHCPHGWVGANCEIHL 620
Score = 136 bits (330), Expect = 3e-31
Identities = 83/272 (30%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD-----DFHCACAAGYAGRTCSLD 475
+SC C + G CE D C + C + A+CID + +F C C GY G C
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+D C PC NG C+ L+ + C CP G+ G+ CE+ D CA SPC N CY +
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 452
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C+C+PG+TG C Q C++ CA G C + GT S++
Sbjct: 453 TCNCSPGFTGPTCAQLI----DFCAL-----SPCAHGTCRSVGT------SYKCLCDPGY 497
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ TC L G+ C C G CEL D C +
Sbjct: 498 HGLYCEEEYNECLSAPCLNAA----TCRD--LVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C C C G+TGE C + ++
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDIN 583
Score = 129 bits (312), Expect = 4e-29
Identities = 89/312 (28%), Positives = 131/312 (41%), Gaps = 42/312 (13%)
Query: 165 CQPNYYNTTCTTF--CRPRDDKFGHYSCTPDGDKH--------CLPGWQGDNCEKPV--- 211
C+ Y T C + C+ + + + SC +K CLPG+ G+ C+ +
Sbjct: 338 CEEQYVGTFCEEYDACQRKPCQ-NNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYC 396
Query: 212 ----CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ----CQPYPGCKHGYC--NGSSWDC 261
C+ G C C G+ G C + C P +G C +G + C
Sbjct: 397 ILDPCRNGATCISSLSGFT--CQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTC 454
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
C + G C Q +++C PC HG TC + Y C C G+ G+ CE N C
Sbjct: 455 NCSPGFTGPTCAQLIDFCAL-SPCAHG-TCRSVGTS-YKCLCDPGYHGLYCEEEYNECLS 511
Query: 322 QPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC-RDHLDGFTCE 379
PC + TC G+ C C + G A+ CL+GA+C D L+G TC
Sbjct: 512 APCLNAATCR--DLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCI 568
Query: 380 CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV 439
CA G+TG C D++EC PC + +C + GY+C C GW G +CE ++
Sbjct: 569 CAPGFTGEECDIDINECDSN--------PCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Query: 440 DDCTGQCLHGAT 451
+G T
Sbjct: 621 QWKSGHMAESLT 632
Score = 66.1 bits (154), Expect = 6e-10
Identities = 50/181 (27%), Positives = 66/181 (36%), Gaps = 24/181 (13%)
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+ C H C C T S+ + C C + G C + A RK C +
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC----QN 360
Query: 566 SERCAEGMCANGG---TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C + G TCV G D + G TC
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC-------------RNGATC 407
Query: 623 LPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ S G+ C C EG G+ CE +D C SSPC+N G C + C C G+TG TC
Sbjct: 408 ISSL--SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 465
Query: 683 A 683
A
Sbjct: 466 A 466
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/87 (39%), Positives = 42/87 (48%), Gaps = 15/87 (17%)
Query: 479 CAPRPCTNGGECVDLLN------------AYRCICPVGFSGTNCEDDRDHCAGSPC--GN 524
CA +PC NGG C Y C CP G SG NC+ D CA +PC GN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 525 GAACYTAQSD-YYCHCAPGWTGKNCTQ 550
++ ++ SD Y C C G+ G NC Q
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 62.5 bits (145), Expect = 7e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 283 EPCQHGGTCENTA-PDQ----------YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSL 331
+PC++GG C + PD Y C C G SG +C+ V +PCA PC HG CS
Sbjct: 51 QPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSS 110
Query: 332 AGTTR--GFTCTCDRGWGG 348
+ ++ G+ C C+ G+ G
Sbjct: 111 SSSSSSDGYLCICNEGYEG 129
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 226 PGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS-SWDCTCDTNWGGILCDQDLNYCGTHEP 284
PG C +P G +C+ +P P +H G + CTC G C + C ++ P
Sbjct: 45 PGPCAAQPCRNGGVCTS-RPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN-P 102
Query: 285 CQHGG--TCENTAPDQYFCRCAEGFSGVDCER 314
C HG + +++ D Y C C EG+ G +CE+
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 318 PCAPQPCAHG-TCSL-----------AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
PCA QPC +G C+ AG G++CTC G G AS PC H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 366 G---ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G +S DG+ C C +G+ GP C + + TE
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTE 146
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNG---GECVDLLNAYRCICPVGFSGTNCE 511
+ C C AG +G C L D CA PC +G + Y CIC G+ G NCE
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNG---GRCVGGSGWWMCECVAGWTGETC 682
PG++C C G +GA C+L D C S+PC +G S ++C C G+ G C
Sbjct: 76 PGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 46.0 bits (104), Expect = 7e-04
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS-----GWWMCECV 674
G C ++C C E G CE D C PC+N C+ + + C C+
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 381
Query: 675 AGWTGETCAVRV 686
G+TGE C ++
Sbjct: 382 PGYTGELCQSKI 393
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHG---ATCIDLVDDFHCACAAGYAGRTC 472
GYSC C AG +G +C+ D C + C HG ++ D + C C GY G C
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 37.9 bits (84), Expect = 0.18
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 5/62 (8%)
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
G++C C G +G C D C+ G C +++ ++++ GY C C G+ G +
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGN---C--SSSSSSSSDGYLCICNEGYEGPN 131
Query: 435 CE 436
CE
Sbjct: 132 CE 133
>AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF
repeat-containing transmembrane protein protein.
Length = 737
Score = 212 bits (517), Expect = 6e-54
Identities = 106/300 (35%), Positives = 151/300 (50%), Gaps = 23/300 (7%)
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC----ENTAPDQYFCRCAEGFSGVDC 312
+++ CTC+ + G C++ + C +PCQ+ +C E + C C G++G C
Sbjct: 332 ATFSCTCEEQYVGTFCEE-YDAC-QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELC 389
Query: 313 ERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+ + C PC +G ++ + GFTC C G+ G AS PC + +C +
Sbjct: 390 QSKIDYCILDPCRNGATCISSLS-GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTC--Y 446
Query: 373 LDG--FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DG FTC C+ G+TGP CA+ +D C AL PC + C + Y C C G+
Sbjct: 447 VDGVHFTCNCSPGFTGPTCAQLIDFC--------ALSPCAHGT-CRSVGTSYKCLCDPGY 497
Query: 431 TGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
G CE ++C + CL+ ATC DLV+ + C C A Y G C L D CA C NG
Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 557
Query: 490 C-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C D LN CIC GF+G C+ D + C +PC +G +C + Y CHC GW G NC
Sbjct: 558 CDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 209 bits (510), Expect = 4e-53
Identities = 113/326 (34%), Positives = 155/326 (47%), Gaps = 27/326 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---CQPYPGCKHGYC 254
C+PG N + K C T + C C + G C + CQ P + C
Sbjct: 307 CVPGESHANDLECSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASC 364
Query: 255 -------NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
+GS++ C C + G LC ++YC +PC++G TC ++ + C+C EG+
Sbjct: 365 IDANEKQDGSNFTCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSG-FTCQCPEGY 422
Query: 308 SGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G CE +PCA PC + GTC + G FTC C G+ G A PC HG
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPCAHG 480
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+CR + C C G+ G C E+ +EC PC+NAA C + GY C C
Sbjct: 481 -TCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVC 531
Query: 427 LAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
LA + G CE D C CL+GATC + C CA G+ G C +D+++C PC
Sbjct: 532 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCH 591
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCE 511
+GG C+D N Y C CP G+ G NCE
Sbjct: 592 HGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 186 bits (454), Expect = 3e-46
Identities = 94/270 (34%), Positives = 124/270 (45%), Gaps = 16/270 (5%)
Query: 285 CQHGGTCENTAPDQYF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR----GFT 339
C G C + F C C E + G CE D C +PC + + + FT
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C G+ G PC +GA+C L GFTC+C +G+ G AC E VD C
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC--- 434
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD 458
A PC N C ++C C G+TG C +D C C HG TC +
Sbjct: 435 -----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTS 488
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C + ++C PC N C DL+N Y C+C + GT+CE +D CA
Sbjct: 489 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 548
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C NGA C + + C CAPG+TG+ C
Sbjct: 549 NVSCLNGATCDSDGLNGTCICAPGFTGEEC 578
Score = 171 bits (417), Expect = 8e-42
Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 22/280 (7%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPG-DCDCRPGWRGELCSQCQPY---PGCKHGY-CNGS 257
D C++ C+ C + + D C C PG+ GELC Y C++G C S
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS 410
Query: 258 --SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ C C + G C++ ++ C + PCQ+ GTC + C C+ GF+G C ++
Sbjct: 411 LSGFTCQCPEGYFGSACEEKVDPCAS-SPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
+ CA PCAHGTC GT+ + C CD G+ G S PCL+ A+CRD ++G
Sbjct: 469 IDFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG 526
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C C + G C D C+ S C+N A C++ +C C G+TG +C
Sbjct: 527 YECVCLAEYKGTHCELYKDPCANVS--------CLNGATCDSDGLNGTCICAPGFTGEEC 578
Query: 436 ETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ ++++C + C HG +C+D + ++C C G+ G C +
Sbjct: 579 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 165 bits (400), Expect = 9e-40
Identities = 95/313 (30%), Positives = 130/313 (41%), Gaps = 28/313 (8%)
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
F+C C + + G C E+ D C + A C++A ++C CL G+TG C
Sbjct: 334 FSCTCEEQYVGTFC-EEYDACQRKPCQNNA--SCIDANE-KQDGSNFTCVCLPGYTGELC 389
Query: 436 ETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC-VDL 493
++ +D C C +GATCI + F C C GY G C VD CA PC N G C VD
Sbjct: 390 QSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDG 449
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
++ + C C GF+G C D CA SPC +G C + + Y C C PG+ G C
Sbjct: 450 VH-FTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDPGYHGLYCE---- 503
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
EE C C N TC + +
Sbjct: 504 ----------EEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G TC L C C G TG C++ ++ C S+PC +GG C+ + C C
Sbjct: 554 N----GATCDSDGL--NGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 607
Query: 674 VAGWTGETCAVRV 686
GW G C + +
Sbjct: 608 PHGWVGANCEIHL 620
Score = 156 bits (378), Expect = 4e-37
Identities = 100/329 (30%), Positives = 138/329 (41%), Gaps = 38/329 (11%)
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDG--FTCECA 381
G C+ + F+CTC+ + G PC + ASC D DG FTC C
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRK-PCQNNASCIDANEKQDGSNFTCVCL 381
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
G+TG C +D C L PC N A C ++ G++C C G+ G CE VD
Sbjct: 382 PGYTGELCQSKIDYC--------ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDP 433
Query: 442 CTGQ-CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + TC +D V F C C+ G+ G TC+ +D CA PC +G C + +Y+C
Sbjct: 434 CASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKC 491
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 492 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-------- 543
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ CA C NG TC + + D G
Sbjct: 544 ------KDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD----IDINECDSNPCHHG 593
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSL 648
G+CL P G+ C C G GA CE+ L
Sbjct: 594 GSCLDQ--PNGYNCHCPHGWVGANCEIHL 620
Score = 136 bits (330), Expect = 3e-31
Identities = 83/272 (30%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD-----DFHCACAAGYAGRTCSLD 475
+SC C + G CE D C + C + A+CID + +F C C GY G C
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+D C PC NG C+ L+ + C CP G+ G+ CE+ D CA SPC N CY +
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 452
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C+C+PG+TG C Q C++ CA G C + GT S++
Sbjct: 453 TCNCSPGFTGPTCAQLI----DFCAL-----SPCAHGTCRSVGT------SYKCLCDPGY 497
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ TC L G+ C C G CEL D C +
Sbjct: 498 HGLYCEEEYNECLSAPCLNAA----TCRD--LVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C C C G+TGE C + ++
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDIN 583
Score = 129 bits (312), Expect = 4e-29
Identities = 89/312 (28%), Positives = 131/312 (41%), Gaps = 42/312 (13%)
Query: 165 CQPNYYNTTCTTF--CRPRDDKFGHYSCTPDGDKH--------CLPGWQGDNCEKPV--- 211
C+ Y T C + C+ + + + SC +K CLPG+ G+ C+ +
Sbjct: 338 CEEQYVGTFCEEYDACQRKPCQ-NNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYC 396
Query: 212 ----CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ----CQPYPGCKHGYC--NGSSWDC 261
C+ G C C G+ G C + C P +G C +G + C
Sbjct: 397 ILDPCRNGATCISSLSGFT--CQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTC 454
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
C + G C Q +++C PC HG TC + Y C C G+ G+ CE N C
Sbjct: 455 NCSPGFTGPTCAQLIDFCAL-SPCAHG-TCRSVGTS-YKCLCDPGYHGLYCEEEYNECLS 511
Query: 322 QPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC-RDHLDGFTCE 379
PC + TC G+ C C + G A+ CL+GA+C D L+G TC
Sbjct: 512 APCLNAATCR--DLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCI 568
Query: 380 CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV 439
CA G+TG C D++EC PC + +C + GY+C C GW G +CE ++
Sbjct: 569 CAPGFTGEECDIDINECDSN--------PCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Query: 440 DDCTGQCLHGAT 451
+G T
Sbjct: 621 QWKSGHMAESLT 632
Score = 66.1 bits (154), Expect = 6e-10
Identities = 50/181 (27%), Positives = 66/181 (36%), Gaps = 24/181 (13%)
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+ C H C C T S+ + C C + G C + A RK C +
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC----QN 360
Query: 566 SERCAEGMCANGG---TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C + G TCV G D + G TC
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC-------------RNGATC 407
Query: 623 LPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ S G+ C C EG G+ CE +D C SSPC+N G C + C C G+TG TC
Sbjct: 408 ISSL--SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 465
Query: 683 A 683
A
Sbjct: 466 A 466
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/87 (39%), Positives = 42/87 (48%), Gaps = 15/87 (17%)
Query: 479 CAPRPCTNGGECVDLLN------------AYRCICPVGFSGTNCEDDRDHCAGSPC--GN 524
CA +PC NGG C Y C CP G SG NC+ D CA +PC GN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 525 GAACYTAQSD-YYCHCAPGWTGKNCTQ 550
++ ++ SD Y C C G+ G NC Q
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 62.5 bits (145), Expect = 7e-09
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 283 EPCQHGGTCENTA-PDQ----------YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSL 331
+PC++GG C + PD Y C C G SG +C+ V +PCA PC HG CS
Sbjct: 51 QPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSS 110
Query: 332 AGTTR--GFTCTCDRGWGG 348
+ ++ G+ C C+ G+ G
Sbjct: 111 SSSSSSDGYLCICNEGYEG 129
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 226 PGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS-SWDCTCDTNWGGILCDQDLNYCGTHEP 284
PG C +P G +C+ +P P +H G + CTC G C + C ++ P
Sbjct: 45 PGPCAAQPCRNGGVCTS-RPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN-P 102
Query: 285 CQHGG--TCENTAPDQYFCRCAEGFSGVDCER 314
C HG + +++ D Y C C EG+ G +CE+
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 318 PCAPQPCAHG-TCSL-----------AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH 365
PCA QPC +G C+ AG G++CTC G G AS PC H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 366 G---ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G +S DG+ C C +G+ GP C + + TE
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTE 146
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNG---GECVDLLNAYRCICPVGFSGTNCE 511
+ C C AG +G C L D CA PC +G + Y CIC G+ G NCE
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNG---GRCVGGSGWWMCECVAGWTGETC 682
PG++C C G +GA C+L D C S+PC +G S ++C C G+ G C
Sbjct: 76 PGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 46.0 bits (104), Expect = 7e-04
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS-----GWWMCECV 674
G C ++C C E G CE D C PC+N C+ + + C C+
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 381
Query: 675 AGWTGETCAVRV 686
G+TGE C ++
Sbjct: 382 PGYTGELCQSKI 393
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHG---ATCIDLVDDFHCACAAGYAGRTC 472
GYSC C AG +G +C+ D C + C HG ++ D + C C GY G C
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 37.9 bits (84), Expect = 0.18
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 5/62 (8%)
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
G++C C G +G C D C+ G C +++ ++++ GY C C G+ G +
Sbjct: 77 GYSCTCPAGISGANCQLVADPCASNPCHHGN---C--SSSSSSSSDGYLCICNEGYEGPN 131
Query: 435 CE 436
CE
Sbjct: 132 CE 133
>BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophila)
protein.
Length = 618
Score = 208 bits (509), Expect = 6e-53
Identities = 135/439 (30%), Positives = 175/439 (39%), Gaps = 39/439 (8%)
Query: 52 PCRTRFTLCLKEYQSAAAPGGSCSFGRAAS---PVL----GTDSFTLAEPLYTLALPFSF 104
PCR F +CLK S A C+ G A S PV G + L P L +PF
Sbjct: 55 PCRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRD 114
Query: 105 RWTRSFTLILQAYDDY---EYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXX 161
W +F+ I++ + + + P L+ + W
Sbjct: 115 AWPGTFSFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSY 174
Query: 162 XXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKP-VCKEGCHPTH 220
C+P T CT CRPR C P G + C P D CE P VC+ GC P H
Sbjct: 175 RARCEPPAVGTACTRLCRPRS---APSRCGP-GLRPCAP--LEDECEAPLVCRAGCSPEH 228
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G C++PG+C C GW G LC+ C G S T G CD +
Sbjct: 229 GFCEQPGECRCLEGWTGPLCTVPVSTSSCLSP--RGPSSATTGCLVPGPGPCDGN----- 281
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT--TRGF 338
PC +GG+C T P + C C GF G+ CE CA PC +G + G +
Sbjct: 282 ---PCANGGSCSET-PRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAY 337
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSG 398
C C G+ G + PC +G C D C C G+ GP C D+D+C+G
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAG 397
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD 457
R+ C N C G + C+C G+ GRDC D C + C HG C
Sbjct: 398 RA--------CANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFS 449
Query: 458 DFHCACAAGYAGRTCSLDV 476
CACA GY G C V
Sbjct: 450 GLVCACAPGYMGARCEFPV 468
Score = 165 bits (400), Expect = 9e-40
Identities = 79/191 (41%), Positives = 98/191 (51%), Gaps = 12/191 (6%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA-- 419
PC +G SC + F C C G+ G C E SG + +G PC N C A
Sbjct: 282 PCANGGSCSETPRSFECTCPRGFYGLRC-----EVSGVTCADG---PCFNGGLCVGGADP 333
Query: 420 -GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
Y C C G+ G +CE VD C+ Q C +G C+DL C C AG+AG C D+D
Sbjct: 334 DSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLD 393
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
DCA R C NGG CV+ A+RC C +GF G +C + D CA PC +G CY S C
Sbjct: 394 DCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVC 453
Query: 538 HCAPGWTGKNC 548
CAPG+ G C
Sbjct: 454 ACAPGYMGARC 464
Score = 151 bits (366), Expect = 1e-35
Identities = 80/222 (36%), Positives = 102/222 (45%), Gaps = 33/222 (14%)
Query: 378 CECADGWTGPACAEDVDECS------GRSMTEGAL---------GPCVNAAACNNTAGGY 422
C C +GWTGP C V S S T G L PC N +C+ T +
Sbjct: 237 CRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSF 296
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCACAAGYAGRTCSLDVDD 478
C C G+ G CE + C G C +G C+ D + C C G+ G C VD
Sbjct: 297 ECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDR 356
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C+ +PC NGG C+DL +A RC C GF+G CE D D CAG C NG C + C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
CA G+ G++C +RA + CA CA+GG C
Sbjct: 417 CALGFGGRDCRERA--------------DPCAARPCAHGGRC 444
Score = 113 bits (272), Expect = 3e-24
Identities = 84/297 (28%), Positives = 100/297 (33%), Gaps = 42/297 (14%)
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
CA DEC + P C C CL GWTG C V T CL
Sbjct: 207 CAPLEDECEAPLVCRAGCSP--EHGFCEQPG---ECRCLEGWTGPLCTVPVS--TSSCLS 259
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
C G C PC NGG C + ++ C CP GF G
Sbjct: 260 PRGPSSATT----GCLVPGPG--------PCDGNPCANGGSCSETPRSFECTCPRGFYGL 307
Query: 509 NCEDDRDHCAGSPCGNGAACYTA---QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
CE CA PC NG C S Y CHC PG+ G NC +R
Sbjct: 308 RCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV------------- 354
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+RC+ C NGG C+ + R + GGTC+
Sbjct: 355 -DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACAN----GGTCVEG 409
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G G C D C + PC +GGRC +C C G+ G C
Sbjct: 410 G--GAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARC 464
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/202 (29%), Positives = 69/202 (34%), Gaps = 20/202 (9%)
Query: 487 GGECVDLLNAYRCICPVGFSG--TNC-EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
G C ++ C+ P G S T C C G+PC NG +C + C C G+
Sbjct: 245 GPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGF 304
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G C CA+G C NGG CV S
Sbjct: 305 YGLRCEVSGVT--------------CADGPCFNGGLCVGGADP-DSAYICHCPPGFQGSN 349
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
+ GG CL L C CR G G CE LD C C NGG CV
Sbjct: 350 CEKRVDRCSLQPCRNGGLCLD--LGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCV 407
Query: 664 GGSGWWMCECVAGWTGETCAVR 685
G G C C G+ G C R
Sbjct: 408 EGGGAHRCSCALGFGGRDCRER 429
Score = 58.8 bits (136), Expect = 9e-08
Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 5/71 (7%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS---GWWMCECVA 675
GG+C S P + C C G G CE+S C PC NGG CVGG+ ++C C
Sbjct: 286 GGSC--SETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPP 343
Query: 676 GWTGETCAVRV 686
G+ G C RV
Sbjct: 344 GFQGSNCEKRV 354
>AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor
protein.
Length = 618
Score = 208 bits (509), Expect = 6e-53
Identities = 135/439 (30%), Positives = 175/439 (39%), Gaps = 39/439 (8%)
Query: 52 PCRTRFTLCLKEYQSAAAPGGSCSFGRAAS---PVL----GTDSFTLAEPLYTLALPFSF 104
PCR F +CLK S A C+ G A S PV G + L P L +PF
Sbjct: 55 PCRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRD 114
Query: 105 RWTRSFTLILQAYDDY---EYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXX 161
W +F+ I++ + + + P L+ + W
Sbjct: 115 AWPGTFSFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSY 174
Query: 162 XXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKP-VCKEGCHPTH 220
C+P T CT CRPR C P G + C P D CE P VC+ GC P H
Sbjct: 175 RARCEPPAVGTACTRLCRPRS---APSRCGP-GLRPCAP--LEDECEAPLVCRAGCSPEH 228
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G C++PG+C C GW G LC+ C G S T G CD +
Sbjct: 229 GFCEQPGECRCLEGWTGPLCTVPVSTSSCLSP--RGPSSATTGCLVPGPGPCDGN----- 281
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT--TRGF 338
PC +GG+C T P + C C GF G+ CE CA PC +G + G +
Sbjct: 282 ---PCANGGSCSET-PRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAY 337
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSG 398
C C G+ G + PC +G C D C C G+ GP C D+D+C+G
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAG 397
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD 457
R+ C N C G + C+C G+ GRDC D C + C HG C
Sbjct: 398 RA--------CANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFS 449
Query: 458 DFHCACAAGYAGRTCSLDV 476
CACA GY G C V
Sbjct: 450 GLVCACAPGYMGARCEFPV 468
Score = 165 bits (400), Expect = 9e-40
Identities = 79/191 (41%), Positives = 98/191 (51%), Gaps = 12/191 (6%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA-- 419
PC +G SC + F C C G+ G C E SG + +G PC N C A
Sbjct: 282 PCANGGSCSETPRSFECTCPRGFYGLRC-----EVSGVTCADG---PCFNGGLCVGGADP 333
Query: 420 -GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
Y C C G+ G +CE VD C+ Q C +G C+DL C C AG+AG C D+D
Sbjct: 334 DSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLD 393
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
DCA R C NGG CV+ A+RC C +GF G +C + D CA PC +G CY S C
Sbjct: 394 DCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVC 453
Query: 538 HCAPGWTGKNC 548
CAPG+ G C
Sbjct: 454 ACAPGYMGARC 464
Score = 151 bits (366), Expect = 1e-35
Identities = 80/222 (36%), Positives = 102/222 (45%), Gaps = 33/222 (14%)
Query: 378 CECADGWTGPACAEDVDECS------GRSMTEGAL---------GPCVNAAACNNTAGGY 422
C C +GWTGP C V S S T G L PC N +C+ T +
Sbjct: 237 CRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSF 296
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCACAAGYAGRTCSLDVDD 478
C C G+ G CE + C G C +G C+ D + C C G+ G C VD
Sbjct: 297 ECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDR 356
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C+ +PC NGG C+DL +A RC C GF+G CE D D CAG C NG C + C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
CA G+ G++C +RA + CA CA+GG C
Sbjct: 417 CALGFGGRDCRERA--------------DPCAARPCAHGGRC 444
Score = 113 bits (272), Expect = 3e-24
Identities = 84/297 (28%), Positives = 100/297 (33%), Gaps = 42/297 (14%)
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
CA DEC + P C C CL GWTG C V T CL
Sbjct: 207 CAPLEDECEAPLVCRAGCSP--EHGFCEQPG---ECRCLEGWTGPLCTVPVS--TSSCLS 259
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
C G C PC NGG C + ++ C CP GF G
Sbjct: 260 PRGPSSATT----GCLVPGPG--------PCDGNPCANGGSCSETPRSFECTCPRGFYGL 307
Query: 509 NCEDDRDHCAGSPCGNGAACYTA---QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
CE CA PC NG C S Y CHC PG+ G NC +R
Sbjct: 308 RCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV------------- 354
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+RC+ C NGG C+ + R + GGTC+
Sbjct: 355 -DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACAN----GGTCVEG 409
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G G C D C + PC +GGRC +C C G+ G C
Sbjct: 410 G--GAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARC 464
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/202 (29%), Positives = 69/202 (34%), Gaps = 20/202 (9%)
Query: 487 GGECVDLLNAYRCICPVGFSG--TNC-EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
G C ++ C+ P G S T C C G+PC NG +C + C C G+
Sbjct: 245 GPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGF 304
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G C CA+G C NGG CV S
Sbjct: 305 YGLRCEVSGVT--------------CADGPCFNGGLCVGGADP-DSAYICHCPPGFQGSN 349
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
+ GG CL L C CR G G CE LD C C NGG CV
Sbjct: 350 CEKRVDRCSLQPCRNGGLCLD--LGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCV 407
Query: 664 GGSGWWMCECVAGWTGETCAVR 685
G G C C G+ G C R
Sbjct: 408 EGGGAHRCSCALGFGGRDCRER 429
Score = 58.8 bits (136), Expect = 9e-08
Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 5/71 (7%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS---GWWMCECVA 675
GG+C S P + C C G G CE+S C PC NGG CVGG+ ++C C
Sbjct: 286 GGSC--SETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPP 343
Query: 676 GWTGETCAVRV 686
G+ G C RV
Sbjct: 344 GFQGSNCEKRV 354
>AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens
cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to
Delta-like protein 3 precursor. ).
Length = 587
Score = 206 bits (504), Expect = 2e-52
Identities = 135/439 (30%), Positives = 175/439 (39%), Gaps = 39/439 (8%)
Query: 52 PCRTRFTLCLKEYQSAAAPGGSCSFGRAAS---PVL----GTDSFTLAEPLYTLALPFSF 104
PCR F +CLK S A C+ G A S PV G + L P L +PF
Sbjct: 55 PCRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRD 114
Query: 105 RWTRSFTLILQAYDDY---EYSEPEAGLIEEAWWSGIVEPSAEWHXXXXXXXXXXXXXXX 161
W +F+ I++ + + + P L+ + W
Sbjct: 115 AWPGTFSFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRCSY 174
Query: 162 XXLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKP-VCKEGCHPTH 220
C+P T CT CRPR C P G + C P D CE P VC+ GC P H
Sbjct: 175 RARCEPPAVGTACTRLCRPRS---APSRCGP-GLRPCAP--LEDECEAPPVCRAGCSPEH 228
Query: 221 GRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCG 280
G C++PG+C C GW G LC+ C G S T G CD +
Sbjct: 229 GFCEQPGECRCLEGWTGPLCTVPVSTSSCLSP--RGPSSATTGCLVPGPGPCDGN----- 281
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT--TRGF 338
PC +GG+C T P + C C GF G+ CE CA PC +G + G +
Sbjct: 282 ---PCANGGSCSET-PRSFECTCPRGFYGLRCEVSGVTCANGPCFNGGLCVGGADPDSAY 337
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSG 398
C C G+ G + PC +G C D C C G+ GP C D+D+C+G
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAG 397
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD 457
R+ C N C G + C+C G+ GRDC D C + C HG C
Sbjct: 398 RA--------CANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAVRPCAHGGRCYAHFS 449
Query: 458 DFHCACAAGYAGRTCSLDV 476
CACA GY G C V
Sbjct: 450 GLVCACAPGYMGARCEFPV 468
Score = 163 bits (396), Expect = 3e-39
Identities = 80/191 (41%), Positives = 98/191 (51%), Gaps = 12/191 (6%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA-- 419
PC +G SC + F C C G+ G C E SG + A GPC N C A
Sbjct: 282 PCANGGSCSETPRSFECTCPRGFYGLRC-----EVSGVTC---ANGPCFNGGLCVGGADP 333
Query: 420 -GGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
Y C C G+ G +CE VD C+ Q C +G C+DL C C AG+AG C D+D
Sbjct: 334 DSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLD 393
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
DCA R C NGG CV+ A+RC C +GF G +C + D CA PC +G CY S C
Sbjct: 394 DCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAVRPCAHGGRCYAHFSGLVC 453
Query: 538 HCAPGWTGKNC 548
CAPG+ G C
Sbjct: 454 ACAPGYMGARC 464
Score = 151 bits (365), Expect = 2e-35
Identities = 80/222 (36%), Positives = 102/222 (45%), Gaps = 33/222 (14%)
Query: 378 CECADGWTGPACAEDVDECS------GRSMTEGAL---------GPCVNAAACNNTAGGY 422
C C +GWTGP C V S S T G L PC N +C+ T +
Sbjct: 237 CRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSF 296
Query: 423 SCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCACAAGYAGRTCSLDVDD 478
C C G+ G CE + C G C +G C+ D + C C G+ G C VD
Sbjct: 297 ECTCPRGFYGLRCEVSGVTCANGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDR 356
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C+ +PC NGG C+DL +A RC C GF+G CE D D CAG C NG C + C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
CA G+ G++C +RA + CA CA+GG C
Sbjct: 417 CALGFGGRDCRERA--------------DPCAVRPCAHGGRC 444
Score = 113 bits (271), Expect = 4e-24
Identities = 84/297 (28%), Positives = 99/297 (33%), Gaps = 42/297 (14%)
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
CA DEC + P C C CL GWTG C V T CL
Sbjct: 207 CAPLEDECEAPPVCRAGCSP--EHGFCEQPG---ECRCLEGWTGPLCTVPVS--TSSCLS 259
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
C G C PC NGG C + ++ C CP GF G
Sbjct: 260 PRGPSSATT----GCLVPGPG--------PCDGNPCANGGSCSETPRSFECTCPRGFYGL 307
Query: 509 NCEDDRDHCAGSPCGNGAACYTA---QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
CE CA PC NG C S Y CHC PG+ G NC +R
Sbjct: 308 RCEVSGVTCANGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV------------- 354
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+RC+ C NGG C+ + R + GGTC+
Sbjct: 355 -DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACAN----GGTCVEG 409
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G G C D C PC +GGRC +C C G+ G C
Sbjct: 410 G--GAHRCSCALGFGGRDCRERADPCAVRPCAHGGRCYAHFSGLVCACAPGYMGARC 464
Score = 77.8 bits (183), Expect = 2e-13
Identities = 59/202 (29%), Positives = 68/202 (33%), Gaps = 20/202 (9%)
Query: 487 GGECVDLLNAYRCICPVGFSG--TNC-EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
G C ++ C+ P G S T C C G+PC NG +C + C C G+
Sbjct: 245 GPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGF 304
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G C CA G C NGG CV S
Sbjct: 305 YGLRCEVSGVT--------------CANGPCFNGGLCVGGADP-DSAYICHCPPGFQGSN 349
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
+ GG CL L C CR G G CE LD C C NGG CV
Sbjct: 350 CEKRVDRCSLQPCRNGGLCLD--LGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCV 407
Query: 664 GGSGWWMCECVAGWTGETCAVR 685
G G C C G+ G C R
Sbjct: 408 EGGGAHRCSCALGFGGRDCRER 429
Score = 59.3 bits (137), Expect = 7e-08
Identities = 29/71 (40%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS---GWWMCECVA 675
GG+C S P + C C G G CE+S C + PC NGG CVGG+ ++C C
Sbjct: 286 GGSC--SETPRSFECTCPRGFYGLRCEVSGVTCANGPCFNGGLCVGGADPDSAYICHCPP 343
Query: 676 GWTGETCAVRV 686
G+ G C RV
Sbjct: 344 GFQGSNCEKRV 354
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1249
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1250 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1301
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1302 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1361
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1362 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 1201 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1256
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1257 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1314
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1315 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1422
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1252
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1373 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1405
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 1188 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1247
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1248 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1307
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1353
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1354 CKNGATCKDGANSFR 1368
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1307
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1363
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1364 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Query: 686 VS 687
S
Sbjct: 1422 QS 1423
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1256 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1301
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1302 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1355
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1356 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1385
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 1219 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1276
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1277 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1334
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1335 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1393
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1394 NQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/110 (35%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C +G C C+C G+ GR C + C PC NGG CV Y+C C
Sbjct: 3475 CRFPCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRCVA---PYQCDC 3525
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
P G++G+ C SPC NG C CHC WTG NC+++
Sbjct: 3526 PPGWTGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNCSRK 3569
Score = 61.7 bits (143), Expect = 1e-08
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 22/112 (19%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G C+ C C +GW G C E + + PC+N C
Sbjct: 3478 PCQNGGICQRPN---ACSCPEGWMGRLCEEPI-----------CILPCLNGGRC---VAP 3520
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
Y C C GWTG C T V C CL+G C V C C + + G CS
Sbjct: 3521 YQCDCPPGWTGSRCHTAV--CQSPCLNGGKC---VRPNRCHCLSSWTGHNCS 3567
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 202 WQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDC 261
W + VC+ C G C RP C C GW G LC + C +G + + C
Sbjct: 3465 WTSPPICRAVCRFPCQ-NGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQC 3523
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C W G C + C PC +GG C P++ C C ++G +C R
Sbjct: 3524 DCPPGWTGSRCHTAV--C--QSPCLNGGKC--VRPNR--CHCLSSWTGHNCSR 3568
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC--SQCQPYPGCKHGYCN 255
C GW G CE+P+C C GRC P CDC PGW G C + CQ P G C
Sbjct: 3493 CPEGWMGRLCEEPICILPC-LNGGRCVAPYQCDCPPGWTGSRCHTAVCQS-PCLNGGKCV 3550
Query: 256 GSSWDCTCDTNWGGILCDQ 274
+ C C ++W G C +
Sbjct: 3551 RPN-RCHCLSSWTGHNCSR 3568
Score = 52.4 bits (120), Expect = 8e-06
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
AC C EG G LCE + + PC NGGRCV + C+C GWTG C V
Sbjct: 3490 ACSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV 3538
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C G TG+ C ++ C SPC NGG+CV + C C++ WTG C+
Sbjct: 3521 YQCDCPPGWTGSRCHTAV--C-QSPCLNGGKCVRPN---RCHCLSSWTGHNCS 3567
Score = 41.1 bits (92), Expect = 0.019
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 513 DRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWT--GKNCTQ 550
D D CA GS C A+C Y C C P +T GKNC +
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAE 1788
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 380 CADG--WTG--PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
C D W G P+C DVDEC+ S C A+C N G Y C+C+ +TG
Sbjct: 1733 CTDNGSWNGVSPSCL-DVDECAVGS-------DCSEHASCLNVDGSYICSCVPSYTG 1781
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 1169 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1226
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1227 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1279 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1338
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1339 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 1178 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1233
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1234 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1291
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1292 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1346 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1399
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1229
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1350 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1382
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 1165 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1224
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1225 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1330
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1331 CKNGATCKDGANSFR 1345
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1238
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1284
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1340
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1341 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398
Query: 686 VS 687
S
Sbjct: 1399 QS 1400
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1233 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1279 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1332
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1333 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1362
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 1196 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1253
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1254 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1311
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1312 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1370
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1371 NQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/110 (35%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C +G C C+C G+ GR C + C PC NGG CV Y+C C
Sbjct: 3449 CRFPCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRCVA---PYQCDC 3499
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
P G++G+ C SPC NG C CHC WTG NC+++
Sbjct: 3500 PPGWTGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNCSRK 3543
Score = 61.7 bits (143), Expect = 1e-08
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 22/112 (19%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G C+ C C +GW G C E + + PC+N C
Sbjct: 3452 PCQNGGICQRPN---ACSCPEGWMGRLCEEPI-----------CILPCLNGGRC---VAP 3494
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
Y C C GWTG C T V C CL+G C V C C + + G CS
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--CQSPCLNGGKC---VRPNRCHCLSSWTGHNCS 3541
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 202 WQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDC 261
W + VC+ C G C RP C C GW G LC + C +G + + C
Sbjct: 3439 WTSPPICRAVCRFPCQ-NGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQC 3497
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C W G C + C PC +GG C P++ C C ++G +C R
Sbjct: 3498 DCPPGWTGSRCHTAV--C--QSPCLNGGKC--VRPNR--CHCLSSWTGHNCSR 3542
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC--SQCQPYPGCKHGYCN 255
C GW G CE+P+C C GRC P CDC PGW G C + CQ P G C
Sbjct: 3467 CPEGWMGRLCEEPICILPC-LNGGRCVAPYQCDCPPGWTGSRCHTAVCQS-PCLNGGKCV 3524
Query: 256 GSSWDCTCDTNWGGILCDQ 274
+ C C ++W G C +
Sbjct: 3525 RPN-RCHCLSSWTGHNCSR 3542
Score = 52.4 bits (120), Expect = 8e-06
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
AC C EG G LCE + + PC NGGRCV + C+C GWTG C V
Sbjct: 3464 ACSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV 3512
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C G TG+ C ++ C SPC NGG+CV + C C++ WTG C+
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--C-QSPCLNGGKCVRPN---RCHCLSSWTGHNCS 3541
Score = 40.3 bits (90), Expect = 0.033
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 513 DRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWT--GKNCTQ 550
D D CA GS C A+C Y C C P +T GKNC +
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1762
Score = 35.5 bits (78), Expect = 0.95
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 380 CADG--WTG--PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
C D W G P+C DVDEC+ S C A+C N G Y C+C+ +TG
Sbjct: 1707 CTDNGSWNGVSPSCL-DVDECAVGS-------DCSEHASCLNVDGSYICSCVPPYTG 1755
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 1169 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1226
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1227 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1279 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1338
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1339 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 1178 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1233
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1234 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1291
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1292 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1346 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1399
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1229
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1350 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1382
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 1165 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1224
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1225 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1330
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1331 CKNGATCKDGANSFR 1345
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1238
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1284
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1340
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1341 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398
Query: 686 VS 687
S
Sbjct: 1399 QS 1400
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1233 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1279 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1332
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1333 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1362
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 1196 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1253
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1254 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1311
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1312 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1370
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1371 NQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/110 (35%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C +G C C+C G+ GR C + C PC NGG CV Y+C C
Sbjct: 3449 CRFPCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRCVA---PYQCDC 3499
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
P G++G+ C SPC NG C CHC WTG NC+++
Sbjct: 3500 PPGWTGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNCSRK 3543
Score = 61.7 bits (143), Expect = 1e-08
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 22/112 (19%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G C+ C C +GW G C E + + PC+N C
Sbjct: 3452 PCQNGGICQRPN---ACSCPEGWMGRLCEEPI-----------CILPCLNGGRC---VAP 3494
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
Y C C GWTG C T V C CL+G C V C C + + G CS
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--CQSPCLNGGKC---VRPNRCHCLSSWTGHNCS 3541
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 202 WQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDC 261
W + VC+ C G C RP C C GW G LC + C +G + + C
Sbjct: 3439 WTSPPICRAVCRFPCQ-NGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQC 3497
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C W G C + C PC +GG C P++ C C ++G +C R
Sbjct: 3498 DCPPGWTGSRCHTAV--C--QSPCLNGGKC--VRPNR--CHCLSSWTGHNCSR 3542
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC--SQCQPYPGCKHGYCN 255
C GW G CE+P+C C GRC P CDC PGW G C + CQ P G C
Sbjct: 3467 CPEGWMGRLCEEPICILPC-LNGGRCVAPYQCDCPPGWTGSRCHTAVCQS-PCLNGGKCV 3524
Query: 256 GSSWDCTCDTNWGGILCDQ 274
+ C C ++W G C +
Sbjct: 3525 RPN-RCHCLSSWTGHNCSR 3542
Score = 52.4 bits (120), Expect = 8e-06
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
AC C EG G LCE + + PC NGGRCV + C+C GWTG C V
Sbjct: 3464 ACSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV 3512
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C G TG+ C ++ C SPC NGG+CV + C C++ WTG C+
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--C-QSPCLNGGKCVRPN---RCHCLSSWTGHNCS 3541
Score = 40.3 bits (90), Expect = 0.033
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 513 DRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWT--GKNCTQ 550
D D CA GS C A+C Y C C P +T GKNC +
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1762
Score = 35.5 bits (78), Expect = 0.95
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 380 CADG--WTG--PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
C D W G P+C DVDEC+ S C A+C N G Y C+C+ +TG
Sbjct: 1707 CTDNGSWNGVSPSCL-DVDECAVGS-------DCSEHASCLNVDGSYICSCVPPYTG 1755
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 1169 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1226
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1227 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1279 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1338
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1339 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 1178 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1233
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1234 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1291
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1292 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1346 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1399
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 1178 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1229
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1230 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1350 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1382
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 1165 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1224
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1225 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1284
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1330
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1331 CKNGATCKDGANSFR 1345
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1238
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1284
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1285 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1340
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1341 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398
Query: 686 VS 687
S
Sbjct: 1399 QS 1400
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1233 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1278
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1279 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1332
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1333 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1362
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 1196 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1253
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1254 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1311
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1312 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1370
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1371 NQATCVDELNSYSCKCQPGFSGKRC 1395
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/110 (35%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C +G C C+C G+ GR C + C PC NGG CV Y+C C
Sbjct: 3449 CRFPCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRCVA---PYQCDC 3499
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
P G++G+ C SPC NG C CHC WTG NC+++
Sbjct: 3500 PPGWTGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNCSRK 3543
Score = 61.7 bits (143), Expect = 1e-08
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 22/112 (19%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G C+ C C +GW G C E + + PC+N C
Sbjct: 3452 PCQNGGICQRPN---ACSCPEGWMGRLCEEPI-----------CILPCLNGGRC---VAP 3494
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
Y C C GWTG C T V C CL+G C V C C + + G CS
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--CQSPCLNGGKC---VRPNRCHCLSSWTGHNCS 3541
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 202 WQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDC 261
W + VC+ C G C RP C C GW G LC + C +G + + C
Sbjct: 3439 WTSPPICRAVCRFPCQ-NGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQC 3497
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C W G C + C PC +GG C P++ C C ++G +C R
Sbjct: 3498 DCPPGWTGSRCHTAV--C--QSPCLNGGKC--VRPNR--CHCLSSWTGHNCSR 3542
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC--SQCQPYPGCKHGYCN 255
C GW G CE+P+C C GRC P CDC PGW G C + CQ P G C
Sbjct: 3467 CPEGWMGRLCEEPICILPC-LNGGRCVAPYQCDCPPGWTGSRCHTAVCQS-PCLNGGKCV 3524
Query: 256 GSSWDCTCDTNWGGILCDQ 274
+ C C ++W G C +
Sbjct: 3525 RPN-RCHCLSSWTGHNCSR 3542
Score = 52.4 bits (120), Expect = 8e-06
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
AC C EG G LCE + + PC NGGRCV + C+C GWTG C V
Sbjct: 3464 ACSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV 3512
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C G TG+ C ++ C SPC NGG+CV + C C++ WTG C+
Sbjct: 3495 YQCDCPPGWTGSRCHTAV--C-QSPCLNGGKCVRPN---RCHCLSSWTGHNCS 3541
Score = 40.3 bits (90), Expect = 0.033
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 513 DRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWT--GKNCTQ 550
D D CA GS C A+C Y C C P +T GKNC +
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1762
Score = 35.5 bits (78), Expect = 0.95
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 380 CADG--WTG--PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
C D W G P+C DVDEC+ S C A+C N G Y C+C+ +TG
Sbjct: 1707 CTDNGSWNGVSPSCL-DVDECAVGS-------DCSEHASCLNVDGSYICSCVPPYTG 1755
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 959 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1016
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1017 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1068
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1069 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1128
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1129 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1185
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 968 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1023
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1024 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1081
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1082 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1135
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1136 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1189
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 968 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1019
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1020 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1079
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1080 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1139
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1140 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1172
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 955 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1014
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1015 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1074
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1075 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1120
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1121 CKNGATCKDGANSFR 1135
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 969 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1028
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1029 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1074
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1075 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1130
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1131 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1188
Query: 686 VS 687
S
Sbjct: 1189 QS 1190
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 963 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1022
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1023 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1068
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1069 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1122
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1123 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1152
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 986 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1043
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1044 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1101
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1102 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1160
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1161 NQATCVDELNSYSCKCQPGFSGKRC 1185
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 204 bits (498), Expect = 1e-51
Identities = 90/237 (37%), Positives = 127/237 (53%), Gaps = 12/237 (5%)
Query: 314 RVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
+V + C PC + GTC G RG+ C C G+ G + PCL+ C+D
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL 1249
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+ F CEC G+TG C E+++ECS PC+N C + GY C C+ G+ G
Sbjct: 1250 VGEFICECPSGYTGQRCEENINECSS--------SPCLNKGICVDGVAGYRCTCVKGFVG 1301
Query: 433 RDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CET V++C + CL+ A C D V F C C G+ G C +VD+C +PC NG C
Sbjct: 1302 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK 1361
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D N++RC+C GF+G++CE + + C +PC N A C + Y C C PG++GK C
Sbjct: 1362 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 191 bits (466), Expect = 9e-48
Identities = 90/234 (38%), Positives = 121/234 (51%), Gaps = 15/234 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCS-LAGTTRGFTCT 341
PC + GTC+ Y C C G++G+ CE + C+P PC + G C L G F C
Sbjct: 1201 PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE---FICE 1256
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G +S PCL+ C D + G+ C C G+ G C +V+EC
Sbjct: 1257 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-- 1314
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFH 460
PC+N A C + GG+ C C G+ G C NVD+C Q C +GATC D + F
Sbjct: 1315 ------PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
C CAAG+ G C L++++C PC N CVD LN+Y C C GFSG CE ++
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1422
Score = 169 bits (410), Expect = 6e-41
Identities = 78/227 (34%), Positives = 111/227 (48%), Gaps = 23/227 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC + +C+ G+ C C G+TG C D+DECS PC+N C + G
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL--------PCLNNGVCKDLVGE 1252
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C C +G+TG+ CE N+++C+ CL+ C+D V + C C G+ G C +V++C
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N C D + + C CP GF GT C + D C PC NGA C + + C CA
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
G+TG +C + + E C C N TCV E S+
Sbjct: 1373 AGFTGSHC-----------ELNINE---CQSNPCRNQATCVDELNSY 1405
Score = 151 bits (366), Expect = 1e-35
Identities = 69/195 (35%), Positives = 95/195 (48%), Gaps = 15/195 (7%)
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCI 453
E S + E PC N+ C GY C C G+TG CET++D+C+ CL+ C
Sbjct: 1188 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK 1247
Query: 454 DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
DLV +F C C +GY G+ C ++++C+ PC N G CVD + YRC C GF G +CE +
Sbjct: 1248 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1307
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ C +PC N A C + C C PG+ G C + + C
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV--------------DECLSQP 1353
Query: 574 CANGGTCVREEGSWR 588
C NG TC S+R
Sbjct: 1354 CKNGATCKDGANSFR 1368
Score = 138 bits (333), Expect = 1e-31
Identities = 72/242 (29%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C + TC L + C C GY G C D+D+C+P PC N G C DL+ + C CP G+
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G CE++ + C+ SPC N C + Y C C G+ G +C E
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET--------------E 1307
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
C C N C + G + + + G TC
Sbjct: 1308 VNECQSNPCLNNAVCEDQVGGF----LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1363
Query: 626 ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
A + C C G TG+ CEL+++ C S+PCRN CV + C+C G++G+ C
Sbjct: 1364 A--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Query: 686 VS 687
S
Sbjct: 1422 QS 1423
Score = 110 bits (265), Expect = 2e-23
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 20/210 (9%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
+C PC N G C L Y C+CP+G++G CE D D C+ PC N C ++ C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+TG+ C E C+ C N G CV +R
Sbjct: 1256 ECPSGYTGQRCE--------------ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1301
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
++ C G+ C C G G C ++D C S PC+
Sbjct: 1302 LHCETEVNECQSNPCLN----NAVCEDQV--GGFLCKCPPGFLGTRCGKNVDECLSQPCK 1355
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
NG C G+ + C C AG+TG C + ++
Sbjct: 1356 NGATCKDGANSFRCLCAAGFTGSHCELNIN 1385
Score = 107 bits (256), Expect = 3e-22
Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP----THGRC-DRPGD--CDCRPGWRGELC----SQCQPY 246
C G+ G CE + + C P +G C D G+ C+C G+ G+ C ++C
Sbjct: 1219 CPLGYTGLKCETDI--DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1276
Query: 247 PGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
P G C +G + + CTC + G+ C+ ++N C ++ PC + CE+ + C+C
Sbjct: 1277 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN-PCLNNAVCEDQV-GGFLCKCP 1334
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
GF G C + + C QPC +G G F C C G+ G S PC
Sbjct: 1335 PGFLGTRCGKNVDECLSQPCKNGATCKDG-ANSFRCLCAAGFTGSHCELNINECQSNPCR 1393
Query: 365 HGASCRDHLDGFTCECADGWTGPAC 389
+ A+C D L+ ++C+C G++G C
Sbjct: 1394 NQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/110 (35%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C +G C C+C G+ GR C + C PC NGG CV Y+C C
Sbjct: 3475 CRFPCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRCVA---PYQCDC 3525
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
P G++G+ C SPC NG C CHC WTG NC+++
Sbjct: 3526 PPGWTGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNCSRK 3569
Score = 61.7 bits (143), Expect = 1e-08
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 22/112 (19%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G C+ C C +GW G C E + + PC+N C
Sbjct: 3478 PCQNGGICQRPN---ACSCPEGWMGRLCEEPI-----------CILPCLNGGRC---VAP 3520
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
Y C C GWTG C T V C CL+G C V C C + + G CS
Sbjct: 3521 YQCDCPPGWTGSRCHTAV--CQSPCLNGGKC---VRPNRCHCLSSWTGHNCS 3567
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 202 WQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDC 261
W + VC+ C G C RP C C GW G LC + C +G + + C
Sbjct: 3465 WTSPPICRAVCRFPCQ-NGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQC 3523
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C W G C + C PC +GG C P++ C C ++G +C R
Sbjct: 3524 DCPPGWTGSRCHTAV--C--QSPCLNGGKC--VRPNR--CHCLSSWTGHNCSR 3568
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC--SQCQPYPGCKHGYCN 255
C GW G CE+P+C C GRC P CDC PGW G C + CQ P G C
Sbjct: 3493 CPEGWMGRLCEEPICILPC-LNGGRCVAPYQCDCPPGWTGSRCHTAVCQS-PCLNGGKCV 3550
Query: 256 GSSWDCTCDTNWGGILCDQ 274
+ C C ++W G C +
Sbjct: 3551 RPN-RCHCLSSWTGHNCSR 3568
Score = 52.4 bits (120), Expect = 8e-06
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
AC C EG G LCE + + PC NGGRCV + C+C GWTG C V
Sbjct: 3490 ACSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV 3538
Score = 47.2 bits (107), Expect = 3e-04
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C G TG+ C ++ C SPC NGG+CV + C C++ WTG C+
Sbjct: 3521 YQCDCPPGWTGSRCHTAV--C-QSPCLNGGKCVRPN---RCHCLSSWTGHNCS 3567
Score = 41.1 bits (92), Expect = 0.019
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 513 DRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWT--GKNCTQ 550
D D CA GS C A+C Y C C P +T GKNC +
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAE 1788
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 380 CADG--WTG--PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
C D W G P+C DVDEC+ S C A+C N G Y C+C+ +TG
Sbjct: 1733 CTDNGSWNGVSPSCL-DVDECAVGS-------DCSEHASCLNVDGSYICSCVPSYTG 1781
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 192 bits (467), Expect = 7e-48
Identities = 91/266 (34%), Positives = 128/266 (48%), Gaps = 10/266 (3%)
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
+S+ C C + G+ C+ ++N C T C +GGTC + + + C C GF+G C
Sbjct: 3 NSYTCKCQAGFDGVHCENNINEC-TESSCFNGGTCVDGI-NSFSCLCPVGFTGSFCLHEI 60
Query: 317 NPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
N C+ PC + GTC GT R C+C G+ G + PC + +C
Sbjct: 61 NECSSHPCLNDGTCVDGLGTYR---CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKA 117
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACLAGWTG 432
C C GW G C C + G L C ++ C N + C C G+TG
Sbjct: 118 SPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTG 177
Query: 433 RDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE +D+C C HGATC D + + C C GY G C +VD+C +PC NGG C+
Sbjct: 178 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCI 237
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHC 517
DL+N ++C CP G G CE++ D C
Sbjct: 238 DLVNHFKCSCPPGTRGLLCEENIDDC 263
Score = 179 bits (435), Expect = 5e-44
Identities = 90/265 (33%), Positives = 116/265 (43%), Gaps = 20/265 (7%)
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ Y C+C GF GV CE N C C +G + G F+C C G+ G
Sbjct: 3 NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGIN-SFSCLCPVGFTGSFCLHEIN 61
Query: 357 XXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
+S PCL+ +C D L + C C G+TG C V+ CS RS PC N C
Sbjct: 62 ECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCS-RS-------PCKNKGTCV 113
Query: 417 NTAGGYSCACLAGWTGRDCET-NVD-DCTGQ---------CLHGATCIDLVDDFHCACAA 465
C C +GW G C+ NV D C H CI+ + +C C
Sbjct: 114 QKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPV 173
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
GY G C +D+CA PC +G C D + YRC C G+ G NCE + D C PC NG
Sbjct: 174 GYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNG 233
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQ 550
C + + C C PG G C +
Sbjct: 234 GTCIDLVNHFKCSCPPGTRGLLCEE 258
Score = 176 bits (428), Expect = 4e-43
Identities = 83/262 (31%), Positives = 118/262 (45%), Gaps = 11/262 (4%)
Query: 422 YSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
Y+C C AG+ G CE N+++CT C +G TC+D ++ F C C G+ G C ++++C+
Sbjct: 5 YTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 64
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
PC N G CVD L YRC CP+G++G NC+ + C+ SPC N C ++ C C
Sbjct: 65 SHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKASPQCLCP 124
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
GW G C +C + E +C + G C+ +
Sbjct: 125 SGWVGAYCDV----PNVSCDIAASRRGVLVEHLCQHSGVCINAGNT----HYCQCPVGYT 176
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGG 660
S Q G TC S G+ C C G G CE +D C + PC+NGG
Sbjct: 177 GSYCEEQLDECASNPCQHGATC--SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG 234
Query: 661 RCVGGSGWWMCECVAGWTGETC 682
C+ + C C G G C
Sbjct: 235 TCIDLVNHFKCSCPPGTRGLLC 256
Score = 163 bits (395), Expect = 4e-39
Identities = 81/255 (31%), Positives = 120/255 (47%), Gaps = 33/255 (12%)
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
+TC C G+ G C +G +C D ++ F+C C G+TG C +++ECS
Sbjct: 5 YTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 64
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLV 456
PC+N C + G Y C+C G+TG++C+T V+ C+ C + TC+
Sbjct: 65 SH--------PCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKK 116
Query: 457 DDFHCACAAGYAGRTC---SLDVDDCAPRP-------CTNGGECVDLLNAYRCICPVGFS 506
C C +G+ G C ++ D A R C + G C++ N + C CPVG++
Sbjct: 117 ASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYT 176
Query: 507 GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
G+ CE+ D CA +PC +GA C Y C C PG+ G NC E
Sbjct: 177 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEY--------------EV 222
Query: 567 ERCAEGMCANGGTCV 581
+ C C NGGTC+
Sbjct: 223 DECQNQPCQNGGTCI 237
Score = 142 bits (343), Expect = 7e-33
Identities = 76/237 (32%), Positives = 106/237 (44%), Gaps = 22/237 (9%)
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
V+ + C C AG+ G C ++++C C NGG CVD +N++ C+CPVGF+G+ C + +
Sbjct: 2 VNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEIN 61
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ PC N C Y C C G+TGKNC LV C+ C
Sbjct: 62 ECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNC-----------QTLVN---LCSRSPCK 107
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXD------SXXXXXXXXXXXXXXQAGGTCLPSALPP 629
N GTCV+++ S + D Q G C+ +
Sbjct: 108 NKGTCVQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTH 167
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G TG+ CE LD C S+PC++G C G + CECV G+ G C V
Sbjct: 168 --YCQCPVGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV 222
Score = 138 bits (333), Expect = 1e-31
Identities = 82/291 (28%), Positives = 125/291 (42%), Gaps = 39/291 (13%)
Query: 372 HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+++ +TC+C G+ G C +++EC+ S C N C + +SC C G+T
Sbjct: 1 YVNSYTCKCQAGFDGVHCENNINECTESS--------CFNGGTCVDGINSFSCLCPVGFT 52
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G C +++C+ CL+ TC+D + + C+C GY G+ C V+ C+ PC N G C
Sbjct: 53 GSFCLHEINECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 112
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHC--AGSP--------CGNGAACYTAQSDYYCHCA 540
V + +C+CP G+ G C+ C A S C + C A + +YC C
Sbjct: 113 VQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 172
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+TG C E+ + CA C +G TC G +R
Sbjct: 173 VGYTGSYCE--------------EQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 218
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
+ Q GGTC+ L + C C G G LCE ++D C
Sbjct: 219 E----YEVDECQNQPCQNGGTCID--LVNHFKCSCPPGTRGLLCEENIDDC 263
Score = 79.0 bits (186), Expect = 8e-14
Identities = 58/188 (30%), Positives = 77/188 (40%), Gaps = 32/188 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRCDRPG---DCDCRPGWRG 237
D G Y C+ C G+ G NC+ V C G C + C C GW G
Sbjct: 76 DGLGTYRCS------CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKASPQCLCPSGWVG 129
Query: 238 ELCS----QCQPYPG---------CKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGT 281
C C C+H G C G++ C C + G C++ L+ C +
Sbjct: 130 AYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGSYCEEQLDECAS 189
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTC 340
+ PCQHG TC + Y C C G+ GV+CE + C QPC + GTC F C
Sbjct: 190 N-PCQHGATCSDFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC--IDLVNHFKC 245
Query: 341 TCDRGWGG 348
+C G G
Sbjct: 246 SCPPGTRG 253
Score = 61.7 bits (143), Expect = 1e-08
Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ ++C C G TG+ C ++ C S PC N G CV G G + C C G+T
Sbjct: 33 GGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNDGTCVDGLGTYRCSCPLGYT 90
Query: 679 GETCAVRVS 687
G+ C V+
Sbjct: 91 GKNCQTLVN 99
Score = 37.1 bits (82), Expect = 0.31
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 11/65 (16%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPG--DCDCRPGWRG 237
D G Y C C+PG+QG NCE V C+ G C D C C PG RG
Sbjct: 200 DFIGGYRC------ECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 253
Query: 238 ELCSQ 242
LC +
Sbjct: 254 LLCEE 258
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 191 bits (465), Expect = 1e-47
Identities = 119/378 (31%), Positives = 161/378 (42%), Gaps = 30/378 (7%)
Query: 198 CLPGWQGDNCEKPVCKEGCH-----PTHGRCDRPGD---CDCRPGWRGE--LCSQCQPYP 247
C G+ G CE + C+ P G C G C C L S C P
Sbjct: 105 CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDP 164
Query: 248 GCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
G C+ S+ C C + G C++ + + PC++GGTC+ A +Y C C
Sbjct: 165 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKE-AGGEYHCSCPY 223
Query: 306 GFSGVDCERVDNP--CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC 363
F+G CE + P CA PC +G + + C C G+ G PC
Sbjct: 224 RFTGRHCE-IGKPDSCASGPCHNGGTCFHYIGK-YKCDCPPGFSGRYCEIAPSPCFRSPC 281
Query: 364 LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL---GPCVNAAACNNTAG 420
++G +C D F C C G+ G C +VD + L G + AAA
Sbjct: 282 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAAALYACDR 341
Query: 421 GYS---------CACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGR 470
GYS C W+ +D+C Q CLHG +C D V + C C+ GY G
Sbjct: 342 GYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGA 401
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C L+ D+C PC NGG C +L AY C CP GF G +CE + D C SPC +G C +
Sbjct: 402 HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 461
Query: 531 AQSDYYCHCAPGWTGKNC 548
Y C C G+ G +C
Sbjct: 462 GGGAYLCVCPEGFFGYHC 479
Score = 188 bits (458), Expect = 9e-47
Identities = 125/417 (29%), Positives = 170/417 (40%), Gaps = 57/417 (13%)
Query: 186 GHYSC---TPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGEL 239
G Y C T H LP C C G G CD D C+C G+ G+
Sbjct: 140 GSYLCVCHTDHNASHSLPS----PCNSDPCFNG-----GSCDAHDDSYTCECPRGFHGKH 190
Query: 240 CSQCQPYPGCKHGYCN--------GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
C + +P+ C G C G + C+C + G C+ PC +GGTC
Sbjct: 191 CEKARPHL-CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 249
Query: 292 ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXX 350
+ +Y C C GFSG CE +PC PC +G TC T F C C G+ G
Sbjct: 250 FHYI-GKYKCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTD--FFCHCQAGYMGRR 306
Query: 351 XXXXXXXXASGPCLH----------GASCRDHLD-GFT---------CECADGWTGPACA 390
H GA+ D G++ C+ W+ P
Sbjct: 307 CQAEVDCGPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC 366
Query: 391 EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHG 449
++DEC + PC++ +C + GY C C G+ G CE D+C C +G
Sbjct: 367 LEIDECRSQ--------PCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNG 418
Query: 450 ATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN 509
+C +L + C C AG+ G C +VD C PC +GG C AY C+CP GF G +
Sbjct: 419 GSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPEGFFGYH 478
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEES 566
CE D C SPCG C + + C C G+TG++C + VEES
Sbjct: 479 CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEES 535
Score = 183 bits (446), Expect = 2e-45
Identities = 148/533 (27%), Positives = 205/533 (38%), Gaps = 65/533 (12%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG-CHPTHGRC---DRPGDCDCRPGWRGE 238
D G+Y+C L GD+ C CH G C D+ C+C G+ G
Sbjct: 19 DLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCH-NGGTCVDADQGYVCECPEGFMGL 77
Query: 239 LCSQCQPYP-GCKHG-YCNGSSWD-CTCDTNWGGILCDQDLNY--CGTHEPCQHGGTCEN 293
C + P C++G C G++ C C + G+LC+ ++ C + C GG C
Sbjct: 78 DCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCME 137
Query: 294 TAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXX 353
Y C C + + +PC PC +G S +TC C RG+ G
Sbjct: 138 HG-GSYLCVCHTDHNA--SHSLPSPCNSDPCFNGG-SCDAHDDSYTCECPRGFHGKHCEK 193
Query: 354 XXXXX-ASGPCLHGASCRDHLDGFTCECADGWTGPACA-EDVDECSGRSMTEGALGPCVN 411
+SGPC +G +C++ + C C +TG C D C A GPC N
Sbjct: 194 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC--------ASGPCHN 245
Query: 412 AAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGR 470
C + G Y C C G++GR CE C C++G TC D DF C C AGY GR
Sbjct: 246 GGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGR 305
Query: 471 TCSLDVDDCAPRPCTNG-----GECVDLLNAYRCICPVGFSGTN----CED--------- 512
C +VD P + G + Y C S + C+
Sbjct: 306 RCQAEVDCGPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQ 365
Query: 513 --DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
+ D C PC +G +C + Y C C+ G+ G +C E + C
Sbjct: 366 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL--------------ERDECR 411
Query: 571 EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPG 630
C NGG+C G++ ++ Q GG C
Sbjct: 412 AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPC----QHGGRCESGG--GA 465
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+ C C EG G CE D C SSPC G C+ +G C C G+TGE CA
Sbjct: 466 YLCVCPEGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 518
Score = 178 bits (434), Expect = 7e-44
Identities = 105/317 (33%), Positives = 140/317 (44%), Gaps = 26/317 (8%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILC---DQDLNYCGTHEPCQHGGTCENTAPD 297
C P P G C ++ C C + G+ C D + PC +GGTC + A
Sbjct: 6 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD-ADQ 64
Query: 298 QYFCRCAEGFSGVDC-ERVDNPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXX 355
Y C C EGF G+DC ERV + C C + G C A TT C C G+ G
Sbjct: 65 GYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTT---LCQCPLGFFGLLCEFEI 118
Query: 356 XXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA-LGPCVNAAA 414
PC C D G+ C + C D + S+ PC N +
Sbjct: 119 TAM---PCNMNTQCPD--GGY---CMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGS 170
Query: 415 CNNTAGGYSCACLAGWTGRDCE-TNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTC 472
C+ Y+C C G+ G+ CE C +G C +G TC + ++HC+C + GR C
Sbjct: 171 CDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC 230
Query: 473 SL-DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
+ D CA PC NGG C + Y+C CP GFSG CE C SPC NG C
Sbjct: 231 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDR 290
Query: 532 QSDYYCHCAPGWTGKNC 548
+D++CHC G+ G+ C
Sbjct: 291 DTDFFCHCQAGYMGRRC 307
Score = 176 bits (429), Expect = 3e-43
Identities = 143/472 (30%), Positives = 189/472 (40%), Gaps = 75/472 (15%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
LC + C T P D C G C+ QG CE C EG R
Sbjct: 27 LCAEPFKGLRCETGDHPVPDACLSAPCHNGGT--CVDADQGYVCE---CPEGFMGLDCRE 81
Query: 224 DRPGDCDCRPGWR----------------GELCS------QCQPYPGCKH-GYC--NGSS 258
P DC+CR G R G LC C C GYC +G S
Sbjct: 82 RVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGS 141
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV-DN 317
+ C C T+ L +PC +GG+C+ D Y C C GF G CE+ +
Sbjct: 142 YLCVCHTDHN---ASHSLPSPCNSDPCFNGGSCD-AHDDSYTCECPRGFHGKHCEKARPH 197
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
C+ PC + GTC AG + C+C R G ASGPC +G +C ++
Sbjct: 198 LCSSGPCRNGGTCKEAGGE--YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK 255
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C+C G++G C C RS PCVN C + + C C AG+ GR C
Sbjct: 256 YKCDCPPGFSGRYCEIAPSPCF-RS-------PCVNGGTCEDRDTDFFCHCQAGYMGRRC 307
Query: 436 ETNVDDCTGQCLHGATC----IDLVDDFHCACAAGYA------GRTCS-----------L 474
+ VD + + AT L AC GY+ R C L
Sbjct: 308 QAEVDCGPPEEVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCL 367
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
++D+C +PC +GG C D + Y C+C G+ G +CE +RD C PC NG +C
Sbjct: 368 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGA 427
Query: 535 YYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
Y C C G+ G +C T+ A D C + RC G CV EG
Sbjct: 428 YVCRCPAGFVGVHCETEVDACDSSPC----QHGGRCESG--GGAYLCVCPEG 473
Score = 175 bits (427), Expect = 5e-43
Identities = 144/509 (28%), Positives = 196/509 (38%), Gaps = 64/509 (12%)
Query: 205 DNCEKPVCKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQCQ-PYP-GCKHGYC-NGSS 258
D+C C G G C D G+ C C ++G C P P C C NG +
Sbjct: 4 DDCSPDPCLNG-----GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 58
Query: 259 -------WDCTCDTNWGGILCDQDL-NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
+ C C + G+ C + + + C C++GG C + C+C GF G+
Sbjct: 59 CVDADQGYVCECPEGFMGLDCRERVPDDC----ECRNGGRC--LGANTTLCQCPLGFFGL 112
Query: 311 DCER--VDNPCAPQP-CAHGT-CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
CE PC C G C G + + C C S PC +G
Sbjct: 113 LCEFEITAMPCNMNTQCPDGGYCMEHGGS--YLCVCHTDHNASHSLPSPCN--SDPCFNG 168
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDE-CSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
SC H D +TCEC G+ G C + CS GPC N C G Y C+
Sbjct: 169 GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSS--------GPCRNGGTCKEAGGEYHCS 220
Query: 426 CLAGWTGRDCETNV-DDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C +TGR CE D C +G C +G TC + + C C G++GR C + C P
Sbjct: 221 CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRSP 280
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRD--------HCAGSPCGN--GAACYTAQS 533
C NGG C D + C C G+ G C+ + D H G GAA A
Sbjct: 281 CVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAAALYACD 340
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
Y AP + C + ++E C C +GG+C +
Sbjct: 341 RGYSLSAPSRI-RVCQPHGVWSEPPQCLEIDE---CRSQPCLHGGSCQDRVAGYLCLCST 396
Query: 594 XXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGS 653
+ + GG+C LP + C C G G CE +D C S
Sbjct: 397 GYEGAHCE----LERDECRAHPCRNGGSC--RNLPGAYVCRCPAGFVGVHCETEVDACDS 450
Query: 654 SPCRNGGRCVGGSGWWMCECVAGWTGETC 682
SPC++GGRC G G ++C C G+ G C
Sbjct: 451 SPCQHGGRCESGGGAYLCVCPEGFFGYHC 479
Score = 150 bits (363), Expect = 3e-35
Identities = 96/330 (29%), Positives = 133/330 (40%), Gaps = 33/330 (10%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG-PCVNAAACNNTAG 420
PCL+G SC D + +TC CA+ + G C E + + L PC N C +
Sbjct: 10 PCLNGGSCVDLVGNYTCLCAEPFKGLRC-----ETGDHPVPDACLSAPCHNGGTCVDADQ 64
Query: 421 GYSCACLAGWTGRDCETNV-DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD-- 477
GY C C G+ G DC V DDC +C +G C+ + C C G+ G C ++
Sbjct: 65 GYVCECPEGFMGLDCRERVPDDC--ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAM 121
Query: 478 DCAPRP-CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
C C +GG C++ +Y C+C + ++ C PC NG +C Y
Sbjct: 122 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSP--CNSDPCFNGGSCDAHDDSYT 179
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C G+ GK+C + AR C+ G C NGGTC G +
Sbjct: 180 CECPRGFHGKHCEK--ARPHL-----------CSSGPCRNGGTCKEAGGEYHCSCPYRFT 226
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
+ GGTC + C C G +G CE++ C SPC
Sbjct: 227 GRHCE---IGKPDSCASGPCHNGGTCFHYI--GKYKCDCPPGFSGRYCEIAPSPCFRSPC 281
Query: 657 RNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
NGG C + C C AG+ G C V
Sbjct: 282 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEV 311
Score = 118 bits (283), Expect = 1e-25
Identities = 89/306 (29%), Positives = 119/306 (38%), Gaps = 43/306 (14%)
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETN----VDDC-TGQC 446
DVD+CS PC+N +C + G Y+C C + G CET D C + C
Sbjct: 2 DVDDCSP--------DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPC 53
Query: 447 LHGATCIDLVDDFHCACAAGYAGRTCSLDV-DDCAPRPCTNGGECVDLLNAYRCICPVGF 505
+G TC+D + C C G+ G C V DDC C NGG C+ N C CP+GF
Sbjct: 54 HNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGA-NTTLCQCPLGF 109
Query: 506 SGTNCEDDRDH--C-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G CE + C + C +G C Y C C T N +
Sbjct: 110 FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSP------- 159
Query: 563 VEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
C C NGG+C + S+ + + GGTC
Sbjct: 160 ------CNSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC---RNGGTC 210
Query: 623 LPSALPPGWACGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGET 681
+ + C C TG CE+ D C S PC NGG C G + C+C G++G
Sbjct: 211 KEAG--GEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRY 268
Query: 682 CAVRVS 687
C + S
Sbjct: 269 CEIAPS 274
Score = 101 bits (241), Expect = 2e-20
Identities = 64/213 (30%), Positives = 80/213 (37%), Gaps = 26/213 (12%)
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD----RDHCAGSPCGNGAACY 529
+DVDDC+P PC NGG CVDL+ Y C+C F G CE D C +PC NG C
Sbjct: 1 MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCV 60
Query: 530 TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRX 589
A Y C C G+ G +C +R D C C NGG C+ +
Sbjct: 61 DADQGYVCECPEGFMGLDCRERVPDD---CE-------------CRNGGRCL--GANTTL 102
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
GG C+ + C C + S
Sbjct: 103 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG--GSYLCVCHTDHNASHSLPS-- 158
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S PC NGG C + CEC G+ G+ C
Sbjct: 159 PCNSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 191
Score = 62.5 bits (145), Expect = 7e-09
Identities = 29/68 (42%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG+C G+ C C G GA CEL D C + PCRNGG C G ++C C AG+
Sbjct: 380 GGSCQDRVA--GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 437
Query: 679 GETCAVRV 686
G C V
Sbjct: 438 GVHCETEV 445
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/52 (28%), Positives = 26/52 (50%)
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+C+ +PC NG C + C C PG+ G+ C + + C+ L E++
Sbjct: 905 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETK 956
Score = 43.2 bits (97), Expect = 0.005
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+C+ PC NGG CV +A+ C C GF G CE
Sbjct: 905 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 938
Score = 40.7 bits (91), Expect = 0.025
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C +PC+NGG CV G+ C+C G+ G C
Sbjct: 906 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 937
Score = 39.5 bits (88), Expect = 0.058
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE----RVDNPC 319
+ PCQ+GGTC A D + C C GF G CE +V PC
Sbjct: 907 SENPCQNGGTCVPGA-DAHSCDCGPGFKGRRCELACIKVSRPC 948
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C +G TC+ D C C G+ GR C L + RPCT
Sbjct: 911 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPCT 949
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC N C A +SC C G+ GR CE
Sbjct: 910 PCQNGGTCVPGADAHSCDCGPGFKGRRCE 938
>BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 383
Score = 189 bits (460), Expect = 5e-47
Identities = 88/243 (36%), Positives = 115/243 (47%), Gaps = 13/243 (5%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C+ G G C C HG C G C C PGW G C +C PGC+HG C+
Sbjct: 15 CILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-Q 73
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
W C C + W G CD+D + C T PCQ+GG C +Y C C GF G DCER
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG 133
Query: 318 PC--APQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
PC A PC + G C G FTC C G+ G PC +GA+C D +
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
+ F+C C +G+ G C ++D+C+ R PC A C + + C C +G+ G+
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDDCASR--------PCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 434 DCE 436
CE
Sbjct: 246 TCE 248
Score = 166 bits (404), Expect = 3e-40
Identities = 89/240 (37%), Positives = 116/240 (48%), Gaps = 27/240 (11%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRG 337
C +H HG C APD CRC G+ G+ CER C P C HGTC +
Sbjct: 29 CSSHCDLAHG--C--CAPDGS-CRCDPGWEGLHCER----CVRMPGCQHGTCH-----QP 74
Query: 338 FTCTCDRGWGGXXXXXXXXX-XASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDE 395
+ C C GW G PC +G C G + C C G+ G C
Sbjct: 75 WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134
Query: 396 CSGRSMTEGALGPCVNAAACNNTAG---GYSCACLAGWTGRDCETNVDDCTGQ-CLHGAT 451
C E A PC N C + G ++C CL G+ G CE NVDDC + C +GAT
Sbjct: 135 C------EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGAT 188
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D ++ F C C G+AGR C++++DDCA RPC G C D ++ + C+CP G+ G CE
Sbjct: 189 CLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCE 248
Score = 162 bits (393), Expect = 6e-39
Identities = 87/242 (35%), Positives = 110/242 (45%), Gaps = 26/242 (10%)
Query: 314 RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
R D+ + AHG C+ G+ C CD GW G C HG +C
Sbjct: 25 RADDCSSHCDLAHGCCAPDGS-----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQP- 74
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTG 432
+ C C GW G C +D C+ +S PC N C GG Y C CL G+ G
Sbjct: 75 --WQCICHSGWAGKFCDKDEHICTTQS-------PCQNGGQCMYDGGGEYHCVCLPGFHG 125
Query: 433 RDCETNVDDCT---GQCLHGATCID---LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTN 486
RDCE C C +G C D +F C C G+ G C ++VDDC RPC N
Sbjct: 126 RDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCAN 185
Query: 487 GGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
G C+D +N + C+CP GF+G C + D CA PC GA C D+ C C G+ GK
Sbjct: 186 GATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 547 NC 548
C
Sbjct: 246 TC 247
Score = 151 bits (366), Expect = 1e-35
Identities = 76/214 (35%), Positives = 100/214 (46%), Gaps = 14/214 (6%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---- 242
H C PDG C PGW+G +CE+ V GC HG C +P C C GW G+ C +
Sbjct: 37 HGCCAPDGSCRCDPGWEGLHCERCVRMPGCQ--HGTCHQPWQCICHSGWAGKFCDKDEHI 94
Query: 243 CQPYPGCKHG----YCNGSSWDCTCDTNWGGILCDQDLNYC-GTHEPCQHGGTCENTA-- 295
C C++G Y G + C C + G C++ C PC++GG C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGF 154
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXX 355
+ CRC GF G CE + C +PCA+G L G R F+C C G+ G
Sbjct: 155 ALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINR-FSCLCPEGFAGRFCTINL 213
Query: 356 XXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
AS PC GA CRD + F C C G+ G C
Sbjct: 214 DDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 247
Score = 141 bits (342), Expect = 1e-32
Identities = 82/239 (34%), Positives = 109/239 (45%), Gaps = 25/239 (10%)
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C + HG C C CD W G+ C++ + G CQHG TC P Q C
Sbjct: 29 CSSHCDLAHGCC-APDGSCRCDPGWEGLHCERCVRMPG----CQHG-TCHQ--PWQ--CI 78
Query: 303 CAEGFSGVDCERVDNPCAPQ-PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX--XXA 359
C G++G C++ ++ C Q PC +G + + C C G+ G A
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQA 138
Query: 360 SGPCLHGASCRDHLD---GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
PC +G C+D FTC C G+ G C +VD+C R PC N A C
Sbjct: 139 GSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMR--------PCANGATCL 190
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ +SC C G+ GR C N+DDC + C GA C D V DF C C +GY G+TC L
Sbjct: 191 DGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 109 bits (263), Expect = 4e-23
Identities = 56/152 (36%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 409 CVNAAACNNTA--GGYSCACLAGWTGRDCETNVDDCTGQ--CLHGATCI-DLVDDFHCAC 463
CV C + + C C +GW G+ C+ + CT Q C +G C+ D ++HC C
Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 464 AAGYAGRTCSLDVDDC--APRPCTNGGECVD----LLNAYRCICPVGFSGTNCEDDRDHC 517
G+ GR C C A PC NGG+C D LN + C C VGF G CE + D C
Sbjct: 120 LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN-FTCRCLVGFVGARCEVNVDDC 178
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
PC NGA C + + C C G+ G+ CT
Sbjct: 179 LMRPCANGATCLDGINRFSCLCPEGFAGRFCT 210
Score = 105 bits (251), Expect = 1e-21
Identities = 74/259 (28%), Positives = 104/259 (40%), Gaps = 28/259 (10%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C+ G G+ DDC+ C C D C C G+ G C + C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCC--APDGSCRCDPGWEGLHC----ERCVRMPGC 66
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAAC-YTAQSDYYCHCAPGW 543
G C ++CIC G++G C+ D C SPC NG C Y +Y+C C PG+
Sbjct: 67 QHGTCHQ---PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGF 123
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C ++A C A C NGG C ++G + +
Sbjct: 124 HGRDCERKAG----PCEQ--------AGSPCRNGGQCQDDQG-FALNFTCRCLVGFVGAR 170
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G TCL ++C C EG G C ++LD C S PC+ G RC
Sbjct: 171 CEVNVDDCLMRPCANGATCLDGI--NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCR 228
Query: 664 GGSGWWMCECVAGWTGETC 682
+ C C +G+ G+TC
Sbjct: 229 DRVHDFDCLCPSGYGGKTC 247
Score = 72.1 bits (169), Expect = 9e-12
Identities = 62/240 (25%), Positives = 85/240 (35%), Gaps = 32/240 (13%)
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
G C+ LV C G G+ + DDC+ G C C C G+ G
Sbjct: 4 GCRCLHLVC---LLCILGAPGQP--VRADDCSSHCDLAHGCCAP---DGSCRCDPGWEGL 55
Query: 509 NCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CE C P C +G T + C C GW GK C +D C+
Sbjct: 56 HCE----RCVRMPGCQHG----TCHQPWQCICHSGWAGKFCD----KDEHICTT------ 97
Query: 568 RCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS-A 626
+ C NGG C+ + G D + GG C
Sbjct: 98 ---QSPCQNGGQCMYDGGG-EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQG 153
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ C C G GA CE+++D C PC NG C+ G + C C G+ G C + +
Sbjct: 154 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINL 213
Score = 58.8 bits (136), Expect = 9e-08
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 194 GDKHC--LPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG-----DCDCRPGWRGELCS 241
G+ HC LPG+ G +CE+ C++ P G+C D G C C G+ G C
Sbjct: 113 GEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE 172
Query: 242 ----QCQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
C P C +G + + C C + G C +L+ C + PCQ G C +
Sbjct: 173 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR-PCQRGARCRDRV 231
Query: 296 PDQYFCRCAEGFSGVDCERV 315
D + C C G+ G CE V
Sbjct: 232 HD-FDCLCPSGYGGKTCELV 250
>AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein.
Length = 383
Score = 189 bits (460), Expect = 5e-47
Identities = 88/243 (36%), Positives = 115/243 (47%), Gaps = 13/243 (5%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C+ G G C C HG C G C C PGW G C +C PGC+HG C+
Sbjct: 15 CILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-Q 73
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
W C C + W G CD+D + C T PCQ+GG C +Y C C GF G DCER
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG 133
Query: 318 PC--APQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
PC A PC + G C G FTC C G+ G PC +GA+C D +
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
+ F+C C +G+ G C ++D+C+ R PC A C + + C C +G+ G+
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDDCASR--------PCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 434 DCE 436
CE
Sbjct: 246 TCE 248
Score = 166 bits (404), Expect = 3e-40
Identities = 89/240 (37%), Positives = 116/240 (48%), Gaps = 27/240 (11%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRG 337
C +H HG C APD CRC G+ G+ CER C P C HGTC +
Sbjct: 29 CSSHCDLAHG--C--CAPDGS-CRCDPGWEGLHCER----CVRMPGCQHGTCH-----QP 74
Query: 338 FTCTCDRGWGGXXXXXXXXX-XASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDE 395
+ C C GW G PC +G C G + C C G+ G C
Sbjct: 75 WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134
Query: 396 CSGRSMTEGALGPCVNAAACNNTAG---GYSCACLAGWTGRDCETNVDDCTGQ-CLHGAT 451
C E A PC N C + G ++C CL G+ G CE NVDDC + C +GAT
Sbjct: 135 C------EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGAT 188
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D ++ F C C G+AGR C++++DDCA RPC G C D ++ + C+CP G+ G CE
Sbjct: 189 CLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCE 248
Score = 162 bits (393), Expect = 6e-39
Identities = 87/242 (35%), Positives = 110/242 (45%), Gaps = 26/242 (10%)
Query: 314 RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
R D+ + AHG C+ G+ C CD GW G C HG +C
Sbjct: 25 RADDCSSHCDLAHGCCAPDGS-----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQP- 74
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTG 432
+ C C GW G C +D C+ +S PC N C GG Y C CL G+ G
Sbjct: 75 --WQCICHSGWAGKFCDKDEHICTTQS-------PCQNGGQCMYDGGGEYHCVCLPGFHG 125
Query: 433 RDCETNVDDCT---GQCLHGATCID---LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTN 486
RDCE C C +G C D +F C C G+ G C ++VDDC RPC N
Sbjct: 126 RDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCAN 185
Query: 487 GGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
G C+D +N + C+CP GF+G C + D CA PC GA C D+ C C G+ GK
Sbjct: 186 GATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 547 NC 548
C
Sbjct: 246 TC 247
Score = 151 bits (366), Expect = 1e-35
Identities = 76/214 (35%), Positives = 100/214 (46%), Gaps = 14/214 (6%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---- 242
H C PDG C PGW+G +CE+ V GC HG C +P C C GW G+ C +
Sbjct: 37 HGCCAPDGSCRCDPGWEGLHCERCVRMPGCQ--HGTCHQPWQCICHSGWAGKFCDKDEHI 94
Query: 243 CQPYPGCKHG----YCNGSSWDCTCDTNWGGILCDQDLNYC-GTHEPCQHGGTCENTA-- 295
C C++G Y G + C C + G C++ C PC++GG C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGF 154
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXX 355
+ CRC GF G CE + C +PCA+G L G R F+C C G+ G
Sbjct: 155 ALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINR-FSCLCPEGFAGRFCTINL 213
Query: 356 XXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
AS PC GA CRD + F C C G+ G C
Sbjct: 214 DDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 247
Score = 141 bits (342), Expect = 1e-32
Identities = 82/239 (34%), Positives = 109/239 (45%), Gaps = 25/239 (10%)
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C + HG C C CD W G+ C++ + G CQHG TC P Q C
Sbjct: 29 CSSHCDLAHGCC-APDGSCRCDPGWEGLHCERCVRMPG----CQHG-TCHQ--PWQ--CI 78
Query: 303 CAEGFSGVDCERVDNPCAPQ-PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX--XXA 359
C G++G C++ ++ C Q PC +G + + C C G+ G A
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQA 138
Query: 360 SGPCLHGASCRDHLD---GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
PC +G C+D FTC C G+ G C +VD+C R PC N A C
Sbjct: 139 GSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMR--------PCANGATCL 190
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ +SC C G+ GR C N+DDC + C GA C D V DF C C +GY G+TC L
Sbjct: 191 DGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 109 bits (263), Expect = 4e-23
Identities = 56/152 (36%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 409 CVNAAACNNTA--GGYSCACLAGWTGRDCETNVDDCTGQ--CLHGATCI-DLVDDFHCAC 463
CV C + + C C +GW G+ C+ + CT Q C +G C+ D ++HC C
Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 464 AAGYAGRTCSLDVDDC--APRPCTNGGECVD----LLNAYRCICPVGFSGTNCEDDRDHC 517
G+ GR C C A PC NGG+C D LN + C C VGF G CE + D C
Sbjct: 120 LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN-FTCRCLVGFVGARCEVNVDDC 178
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
PC NGA C + + C C G+ G+ CT
Sbjct: 179 LMRPCANGATCLDGINRFSCLCPEGFAGRFCT 210
Score = 105 bits (251), Expect = 1e-21
Identities = 74/259 (28%), Positives = 104/259 (40%), Gaps = 28/259 (10%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C+ G G+ DDC+ C C D C C G+ G C + C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCC--APDGSCRCDPGWEGLHC----ERCVRMPGC 66
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAAC-YTAQSDYYCHCAPGW 543
G C ++CIC G++G C+ D C SPC NG C Y +Y+C C PG+
Sbjct: 67 QHGTCHQ---PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGF 123
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C ++A C A C NGG C ++G + +
Sbjct: 124 HGRDCERKAG----PCEQ--------AGSPCRNGGQCQDDQG-FALNFTCRCLVGFVGAR 170
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G TCL ++C C EG G C ++LD C S PC+ G RC
Sbjct: 171 CEVNVDDCLMRPCANGATCLDGI--NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCR 228
Query: 664 GGSGWWMCECVAGWTGETC 682
+ C C +G+ G+TC
Sbjct: 229 DRVHDFDCLCPSGYGGKTC 247
Score = 72.1 bits (169), Expect = 9e-12
Identities = 62/240 (25%), Positives = 85/240 (35%), Gaps = 32/240 (13%)
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
G C+ LV C G G+ + DDC+ G C C C G+ G
Sbjct: 4 GCRCLHLVC---LLCILGAPGQP--VRADDCSSHCDLAHGCCAP---DGSCRCDPGWEGL 55
Query: 509 NCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CE C P C +G T + C C GW GK C +D C+
Sbjct: 56 HCE----RCVRMPGCQHG----TCHQPWQCICHSGWAGKFCD----KDEHICTT------ 97
Query: 568 RCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS-A 626
+ C NGG C+ + G D + GG C
Sbjct: 98 ---QSPCQNGGQCMYDGGG-EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQG 153
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ C C G GA CE+++D C PC NG C+ G + C C G+ G C + +
Sbjct: 154 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINL 213
Score = 58.8 bits (136), Expect = 9e-08
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 194 GDKHC--LPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG-----DCDCRPGWRGELCS 241
G+ HC LPG+ G +CE+ C++ P G+C D G C C G+ G C
Sbjct: 113 GEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE 172
Query: 242 ----QCQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
C P C +G + + C C + G C +L+ C + PCQ G C +
Sbjct: 173 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR-PCQRGARCRDRV 231
Query: 296 PDQYFCRCAEGFSGVDCERV 315
D + C C G+ G CE V
Sbjct: 232 HD-FDCLCPSGYGGKTCELV 250
>AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 383
Score = 189 bits (460), Expect = 5e-47
Identities = 88/243 (36%), Positives = 115/243 (47%), Gaps = 13/243 (5%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C+ G G C C HG C G C C PGW G C +C PGC+HG C+
Sbjct: 15 CILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-Q 73
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
W C C + W G CD+D + C T PCQ+GG C +Y C C GF G DCER
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG 133
Query: 318 PC--APQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
PC A PC + G C G FTC C G+ G PC +GA+C D +
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
+ F+C C +G+ G C ++D+C+ R PC A C + + C C +G+ G+
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDDCASR--------PCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 434 DCE 436
CE
Sbjct: 246 TCE 248
Score = 166 bits (404), Expect = 3e-40
Identities = 89/240 (37%), Positives = 116/240 (48%), Gaps = 27/240 (11%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRG 337
C +H HG C APD CRC G+ G+ CER C P C HGTC +
Sbjct: 29 CSSHCDLAHG--C--CAPDGS-CRCDPGWEGLHCER----CVRMPGCQHGTCH-----QP 74
Query: 338 FTCTCDRGWGGXXXXXXXXX-XASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDE 395
+ C C GW G PC +G C G + C C G+ G C
Sbjct: 75 WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134
Query: 396 CSGRSMTEGALGPCVNAAACNNTAG---GYSCACLAGWTGRDCETNVDDCTGQ-CLHGAT 451
C E A PC N C + G ++C CL G+ G CE NVDDC + C +GAT
Sbjct: 135 C------EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGAT 188
Query: 452 CIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C+D ++ F C C G+AGR C++++DDCA RPC G C D ++ + C+CP G+ G CE
Sbjct: 189 CLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCE 248
Score = 162 bits (393), Expect = 6e-39
Identities = 87/242 (35%), Positives = 110/242 (45%), Gaps = 26/242 (10%)
Query: 314 RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
R D+ + AHG C+ G+ C CD GW G C HG +C
Sbjct: 25 RADDCSSHCDLAHGCCAPDGS-----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQP- 74
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTG 432
+ C C GW G C +D C+ +S PC N C GG Y C CL G+ G
Sbjct: 75 --WQCICHSGWAGKFCDKDEHICTTQS-------PCQNGGQCMYDGGGEYHCVCLPGFHG 125
Query: 433 RDCETNVDDCT---GQCLHGATCID---LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTN 486
RDCE C C +G C D +F C C G+ G C ++VDDC RPC N
Sbjct: 126 RDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCAN 185
Query: 487 GGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
G C+D +N + C+CP GF+G C + D CA PC GA C D+ C C G+ GK
Sbjct: 186 GATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGK 245
Query: 547 NC 548
C
Sbjct: 246 TC 247
Score = 151 bits (366), Expect = 1e-35
Identities = 76/214 (35%), Positives = 100/214 (46%), Gaps = 14/214 (6%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---- 242
H C PDG C PGW+G +CE+ V GC HG C +P C C GW G+ C +
Sbjct: 37 HGCCAPDGSCRCDPGWEGLHCERCVRMPGCQ--HGTCHQPWQCICHSGWAGKFCDKDEHI 94
Query: 243 CQPYPGCKHG----YCNGSSWDCTCDTNWGGILCDQDLNYC-GTHEPCQHGGTCENTA-- 295
C C++G Y G + C C + G C++ C PC++GG C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGF 154
Query: 296 PDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXX 355
+ CRC GF G CE + C +PCA+G L G R F+C C G+ G
Sbjct: 155 ALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINR-FSCLCPEGFAGRFCTINL 213
Query: 356 XXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
AS PC GA CRD + F C C G+ G C
Sbjct: 214 DDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 247
Score = 141 bits (342), Expect = 1e-32
Identities = 82/239 (34%), Positives = 109/239 (45%), Gaps = 25/239 (10%)
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C + HG C C CD W G+ C++ + G CQHG TC P Q C
Sbjct: 29 CSSHCDLAHGCC-APDGSCRCDPGWEGLHCERCVRMPG----CQHG-TCHQ--PWQ--CI 78
Query: 303 CAEGFSGVDCERVDNPCAPQ-PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX--XXA 359
C G++G C++ ++ C Q PC +G + + C C G+ G A
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQA 138
Query: 360 SGPCLHGASCRDHLD---GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
PC +G C+D FTC C G+ G C +VD+C R PC N A C
Sbjct: 139 GSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMR--------PCANGATCL 190
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ +SC C G+ GR C N+DDC + C GA C D V DF C C +GY G+TC L
Sbjct: 191 DGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 109 bits (263), Expect = 4e-23
Identities = 56/152 (36%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 409 CVNAAACNNTA--GGYSCACLAGWTGRDCETNVDDCTGQ--CLHGATCI-DLVDDFHCAC 463
CV C + + C C +GW G+ C+ + CT Q C +G C+ D ++HC C
Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 464 AAGYAGRTCSLDVDDC--APRPCTNGGECVD----LLNAYRCICPVGFSGTNCEDDRDHC 517
G+ GR C C A PC NGG+C D LN + C C VGF G CE + D C
Sbjct: 120 LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN-FTCRCLVGFVGARCEVNVDDC 178
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
PC NGA C + + C C G+ G+ CT
Sbjct: 179 LMRPCANGATCLDGINRFSCLCPEGFAGRFCT 210
Score = 105 bits (251), Expect = 1e-21
Identities = 74/259 (28%), Positives = 104/259 (40%), Gaps = 28/259 (10%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C+ G G+ DDC+ C C D C C G+ G C + C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCC--APDGSCRCDPGWEGLHC----ERCVRMPGC 66
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAAC-YTAQSDYYCHCAPGW 543
G C ++CIC G++G C+ D C SPC NG C Y +Y+C C PG+
Sbjct: 67 QHGTCHQ---PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGF 123
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C ++A C A C NGG C ++G + +
Sbjct: 124 HGRDCERKAG----PCEQ--------AGSPCRNGGQCQDDQG-FALNFTCRCLVGFVGAR 170
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
G TCL ++C C EG G C ++LD C S PC+ G RC
Sbjct: 171 CEVNVDDCLMRPCANGATCLDGI--NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCR 228
Query: 664 GGSGWWMCECVAGWTGETC 682
+ C C +G+ G+TC
Sbjct: 229 DRVHDFDCLCPSGYGGKTC 247
Score = 72.1 bits (169), Expect = 9e-12
Identities = 62/240 (25%), Positives = 85/240 (35%), Gaps = 32/240 (13%)
Query: 449 GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
G C+ LV C G G+ + DDC+ G C C C G+ G
Sbjct: 4 GCRCLHLVC---LLCILGAPGQP--VRADDCSSHCDLAHGCCAP---DGSCRCDPGWEGL 55
Query: 509 NCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CE C P C +G T + C C GW GK C +D C+
Sbjct: 56 HCE----RCVRMPGCQHG----TCHQPWQCICHSGWAGKFCD----KDEHICTT------ 97
Query: 568 RCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS-A 626
+ C NGG C+ + G D + GG C
Sbjct: 98 ---QSPCQNGGQCMYDGGG-EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQG 153
Query: 627 LPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ C C G GA CE+++D C PC NG C+ G + C C G+ G C + +
Sbjct: 154 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINL 213
Score = 58.8 bits (136), Expect = 9e-08
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 194 GDKHC--LPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG-----DCDCRPGWRGELCS 241
G+ HC LPG+ G +CE+ C++ P G+C D G C C G+ G C
Sbjct: 113 GEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE 172
Query: 242 ----QCQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
C P C +G + + C C + G C +L+ C + PCQ G C +
Sbjct: 173 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR-PCQRGARCRDRV 231
Query: 296 PDQYFCRCAEGFSGVDCERV 315
D + C C G+ G CE V
Sbjct: 232 HD-FDCLCPSGYGGKTCELV 250
>AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 188 bits (457), Expect = 1e-46
Identities = 104/337 (30%), Positives = 152/337 (45%), Gaps = 45/337 (13%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACA---AGYAGRTCSLDVDDCAPRPCTNGGECVDL----------- 493
+ ATC++ + + C C +GY G C +D+++C PC + GECV+L
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITG 256
Query: 494 ---------LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
+ Y CIC GF+G +CE+D + C+ +PC NG C +Y CHC +
Sbjct: 257 LPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FD 314
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ T RD CS ++ C C N GTC+
Sbjct: 315 NLSRTFYGGRD---CSDIL---LGCTHQQCLNNGTCI 345
Score = 173 bits (420), Expect = 3e-42
Identities = 106/345 (30%), Positives = 145/345 (42%), Gaps = 46/345 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +GA C+D +DG++C C G+ G C +VDEC A PC N A C N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--------ASDPCKNEATCLN 203
Query: 418 TAGGYSCAC---LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------F 459
G Y+C C +G+TG CE ++++C C C++L + +
Sbjct: 204 EIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 460 H------CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSG 507
H C C G+ G C DV++C+ PC NGG C +L Y C CP + G
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 323
Query: 508 TNCEDDRDHCAGSPCGNGAACYT----AQSDYYCHCAPGWTGKNC 548
+C D C C N C Q + C C G+TG C
Sbjct: 324 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 368
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1006 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1063
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1064 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1114
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1115 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1174
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1175 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223
Score = 151 bits (365), Expect = 2e-35
Identities = 87/282 (30%), Positives = 130/282 (46%), Gaps = 33/282 (11%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECA---DGWTGPACAEDVDECSGRSMTEGALGPCVNAAA--------------CNNTAG 420
C C G+TG C D++EC+ G CV ++ + A
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECNSNPCQSN--GECVELSSEKQYGRITGLPSSFSYHEAS 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAG------YAGRTCS 473
GY C C G+TG CE +V++C+ C +G TC +L ++ C C Y GR CS
Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 327
Query: 474 LDVDDCAPRPCTNGGECV----DLLNAYRCICPVGFSGTNCE 511
+ C + C N G C+ D + + C+CP G++G+ CE
Sbjct: 328 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 369
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1033 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1083
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1084 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1143
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1144 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1203
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1204 LNKFQCLCDVAFAGERCEVDLADD 1227
Score = 140 bits (339), Expect = 2e-32
Identities = 86/288 (29%), Positives = 117/288 (40%), Gaps = 38/288 (13%)
Query: 409 CVNAAACNNTAGGYSCAC--LAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD--FHCAC 463
C N + C + + C+C A +DC+ D C + C ATC++ + F C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY+G C + C C +GG C CICP G++G CE D D CA SPC
Sbjct: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQ 158
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NGA C Y C C PG+ G++C E + CA C N TC+ E
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCDL--------------EVDECASDPCKNEATCLNE 204
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC--------------LPSAL-- 627
G + + Q+ G C LPS+
Sbjct: 205 IGRY-TCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 628 --PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 311
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1035 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1093
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1094 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1154 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1199
Query: 580 C 580
C
Sbjct: 1200 C 1200
Score = 129 bits (311), Expect = 6e-29
Identities = 100/348 (28%), Positives = 134/348 (38%), Gaps = 63/348 (18%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKH-GYCNGSSW--DCTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+H G C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDR---GWGGXXXXXXXXXXASGPCLHGASCRD--------------------HLDGFT 377
C G+ G S PC C + G+
Sbjct: 211 ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 270
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC------LAGWT 431
C C G+TG C EDV+ECS PC N C N G Y+C C +
Sbjct: 271 CICQPGFTGIHCEEDVNECSS--------NPCQNGGTCENLPGNYTCHCPFDNLSRTFYG 322
Query: 432 GRDCETNVDDCT-GQCLHGATCIDLVDD----FHCACAAGYAGRTCSL 474
GRDC + CT QCL+ TCI D F C C +GY G C +
Sbjct: 323 GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1023 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1081
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1082 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1128 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1185
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1186 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1222
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1031 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1087
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1088 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1197
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1198 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1109
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1110 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1224
Score = 85.8 bits (203), Expect = 7e-16
Identities = 64/237 (27%), Positives = 90/237 (37%), Gaps = 28/237 (11%)
Query: 435 CETNVDDC-TGQCLHGATCIDLVDDFHCACA--AGYAGRTCSLDVDDCAPRPCTNGGECV 491
C N C + C + +TC D D C+C+ A + C D C PC CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 492 DL--LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+ ++ C CP G+SGT CE C + C +G C+ C C G+ G+ C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 550 QRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++ E CA C NG C ++G
Sbjct: 147 -------------IDHDE-CASSPCQNGAVC--QDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGC---REGRTGALCELSLDLCGSSPCRNGGRCV 663
+A TCL + C C G TGA CE+ L+ C S+PC++ G CV
Sbjct: 191 ASDPCKNEA--TCLNEI--GRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECV 243
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/220 (22%), Positives = 76/220 (34%), Gaps = 27/220 (12%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC---VAGWTGETCAV 684
+D C S PC+N C+ G + C C +G+TG C +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEI 226
Score = 66.9 bits (156), Expect = 3e-10
Identities = 46/177 (25%), Positives = 59/177 (33%), Gaps = 16/177 (9%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
C + C + C N + C D C C+ T N K C + + C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLD-------KDCDNM---KDPC 74
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
C TCV G + Q GG C + P
Sbjct: 75 FSNPCQGSATCVNTPGE--RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP 132
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE+ D C SSPC+NG C G + C CV G+ G C + V
Sbjct: 133 --VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 784 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 842
Query: 506 SG 507
+G
Sbjct: 843 NG 844
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 830
Query: 532 QSDYYC 537
+ C
Sbjct: 831 LQGFEC 836
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1039 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1095
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1096 GVNCEVDI 1103
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1081 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1134
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1193
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1194 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1221
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 764 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 820
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 821 CPHGAQCQPVLQGFECIANAVFNGQS 846
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1026 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1066
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 781 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 831
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 832 QGFECIANAVFNGQ 845
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 777 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 832
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 833 GFECIANAVFNG 844
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 602
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 773 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 812
Score = 36.3 bits (80), Expect = 0.54
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 617 QAGGTCLPSALPPGWACGC---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGS 666
Q GGTC LP + C C RT G C L C C N G C+ G
Sbjct: 295 QNGGTC--ENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 352
Query: 667 GWWMCECVAGWTGETCAV 684
+ C C +G+TG C +
Sbjct: 353 HGFSCLCPSGYTGSLCEI 370
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 595
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 779 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 810
>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 188 bits (457), Expect = 1e-46
Identities = 104/337 (30%), Positives = 152/337 (45%), Gaps = 45/337 (13%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACA---AGYAGRTCSLDVDDCAPRPCTNGGECVDL----------- 493
+ ATC++ + + C C +GY G C +D+++C PC + GECV+L
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITG 256
Query: 494 ---------LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
+ Y CIC GF+G +CE+D + C+ +PC NG C +Y CHC +
Sbjct: 257 LPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FD 314
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ T RD CS ++ C C N GTC+
Sbjct: 315 NLSRTFYGGRD---CSDIL---LGCTHQQCLNNGTCI 345
Score = 173 bits (420), Expect = 3e-42
Identities = 106/345 (30%), Positives = 145/345 (42%), Gaps = 46/345 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +GA C+D +DG++C C G+ G C +VDEC A PC N A C N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--------ASDPCKNEATCLN 203
Query: 418 TAGGYSCAC---LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------F 459
G Y+C C +G+TG CE ++++C C C++L + +
Sbjct: 204 EIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 460 H------CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSG 507
H C C G+ G C DV++C+ PC NGG C +L Y C CP + G
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 323
Query: 508 TNCEDDRDHCAGSPCGNGAACYT----AQSDYYCHCAPGWTGKNC 548
+C D C C N C Q + C C G+TG C
Sbjct: 324 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 368
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1006 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1063
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1064 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1114
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1115 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1174
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1175 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223
Score = 151 bits (365), Expect = 2e-35
Identities = 87/282 (30%), Positives = 130/282 (46%), Gaps = 33/282 (11%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECA---DGWTGPACAEDVDECSGRSMTEGALGPCVNAAA--------------CNNTAG 420
C C G+TG C D++EC+ G CV ++ + A
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECNSNPCQSN--GECVELSSEKQYGRITGLPSSFSYHEAS 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAG------YAGRTCS 473
GY C C G+TG CE +V++C+ C +G TC +L ++ C C Y GR CS
Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 327
Query: 474 LDVDDCAPRPCTNGGECV----DLLNAYRCICPVGFSGTNCE 511
+ C + C N G C+ D + + C+CP G++G+ CE
Sbjct: 328 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 369
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1033 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1083
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1084 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1143
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1144 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1203
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1204 LNKFQCLCDVAFAGERCEVDLADD 1227
Score = 140 bits (339), Expect = 2e-32
Identities = 86/288 (29%), Positives = 117/288 (40%), Gaps = 38/288 (13%)
Query: 409 CVNAAACNNTAGGYSCAC--LAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD--FHCAC 463
C N + C + + C+C A +DC+ D C + C ATC++ + F C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY+G C + C C +GG C CICP G++G CE D D CA SPC
Sbjct: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQ 158
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NGA C Y C C PG+ G++C E + CA C N TC+ E
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCDL--------------EVDECASDPCKNEATCLNE 204
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC--------------LPSAL-- 627
G + + Q+ G C LPS+
Sbjct: 205 IGRY-TCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 628 --PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 311
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1035 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1093
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1094 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1154 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1199
Query: 580 C 580
C
Sbjct: 1200 C 1200
Score = 129 bits (311), Expect = 6e-29
Identities = 100/348 (28%), Positives = 134/348 (38%), Gaps = 63/348 (18%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKH-GYCNGSSW--DCTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+H G C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDR---GWGGXXXXXXXXXXASGPCLHGASCRD--------------------HLDGFT 377
C G+ G S PC C + G+
Sbjct: 211 ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 270
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC------LAGWT 431
C C G+TG C EDV+ECS PC N C N G Y+C C +
Sbjct: 271 CICQPGFTGIHCEEDVNECSS--------NPCQNGGTCENLPGNYTCHCPFDNLSRTFYG 322
Query: 432 GRDCETNVDDCT-GQCLHGATCIDLVDD----FHCACAAGYAGRTCSL 474
GRDC + CT QCL+ TCI D F C C +GY G C +
Sbjct: 323 GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1023 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1081
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1082 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1128 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1185
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1186 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1222
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1031 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1087
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1088 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1197
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1198 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1109
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1110 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1224
Score = 85.8 bits (203), Expect = 7e-16
Identities = 64/237 (27%), Positives = 90/237 (37%), Gaps = 28/237 (11%)
Query: 435 CETNVDDC-TGQCLHGATCIDLVDDFHCACA--AGYAGRTCSLDVDDCAPRPCTNGGECV 491
C N C + C + +TC D D C+C+ A + C D C PC CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 492 DL--LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+ ++ C CP G+SGT CE C + C +G C+ C C G+ G+ C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 550 QRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++ E CA C NG C ++G
Sbjct: 147 -------------IDHDE-CASSPCQNGAVC--QDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGC---REGRTGALCELSLDLCGSSPCRNGGRCV 663
+A TCL + C C G TGA CE+ L+ C S+PC++ G CV
Sbjct: 191 ASDPCKNEA--TCLNEI--GRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECV 243
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/220 (22%), Positives = 76/220 (34%), Gaps = 27/220 (12%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC---VAGWTGETCAV 684
+D C S PC+N C+ G + C C +G+TG C +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEI 226
Score = 66.9 bits (156), Expect = 3e-10
Identities = 46/177 (25%), Positives = 59/177 (33%), Gaps = 16/177 (9%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
C + C + C N + C D C C+ T N K C + + C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLD-------KDCDNM---KDPC 74
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
C TCV G + Q GG C + P
Sbjct: 75 FSNPCQGSATCVNTPGE--RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP 132
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE+ D C SSPC+NG C G + C CV G+ G C + V
Sbjct: 133 --VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 784 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 842
Query: 506 SG 507
+G
Sbjct: 843 NG 844
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 830
Query: 532 QSDYYC 537
+ C
Sbjct: 831 LQGFEC 836
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1039 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1095
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1096 GVNCEVDI 1103
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1081 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1134
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1193
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1194 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1221
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 764 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 820
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 821 CPHGAQCQPVLQGFECIANAVFNGQS 846
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1026 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1066
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 781 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 831
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 832 QGFECIANAVFNGQ 845
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 777 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 832
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 833 GFECIANAVFNG 844
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 602
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 773 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 812
Score = 36.3 bits (80), Expect = 0.54
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 617 QAGGTCLPSALPPGWACGC---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGS 666
Q GGTC LP + C C RT G C L C C N G C+ G
Sbjct: 295 QNGGTC--ENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 352
Query: 667 GWWMCECVAGWTGETCAV 684
+ C C +G+TG C +
Sbjct: 353 HGFSCLCPSGYTGSLCEI 370
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 595
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 779 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 810
>AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 188 bits (457), Expect = 1e-46
Identities = 104/337 (30%), Positives = 152/337 (45%), Gaps = 45/337 (13%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACA---AGYAGRTCSLDVDDCAPRPCTNGGECVDL----------- 493
+ ATC++ + + C C +GY G C +D+++C PC + GECV+L
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITG 256
Query: 494 ---------LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
+ Y CIC GF+G +CE+D + C+ +PC NG C +Y CHC +
Sbjct: 257 LPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FD 314
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ T RD CS ++ C C N GTC+
Sbjct: 315 NLSRTFYGGRD---CSDIL---LGCTHQQCLNNGTCI 345
Score = 173 bits (420), Expect = 3e-42
Identities = 106/345 (30%), Positives = 145/345 (42%), Gaps = 46/345 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +GA C+D +DG++C C G+ G C +VDEC A PC N A C N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--------ASDPCKNEATCLN 203
Query: 418 TAGGYSCAC---LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------F 459
G Y+C C +G+TG CE ++++C C C++L + +
Sbjct: 204 EIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 460 H------CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSG 507
H C C G+ G C DV++C+ PC NGG C +L Y C CP + G
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 323
Query: 508 TNCEDDRDHCAGSPCGNGAACYT----AQSDYYCHCAPGWTGKNC 548
+C D C C N C Q + C C G+TG C
Sbjct: 324 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 368
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1006 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1063
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1064 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1114
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1115 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1174
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1175 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223
Score = 151 bits (365), Expect = 2e-35
Identities = 87/282 (30%), Positives = 130/282 (46%), Gaps = 33/282 (11%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECA---DGWTGPACAEDVDECSGRSMTEGALGPCVNAAA--------------CNNTAG 420
C C G+TG C D++EC+ G CV ++ + A
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECNSNPCQSN--GECVELSSEKQYGRITGLPSSFSYHEAS 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAG------YAGRTCS 473
GY C C G+TG CE +V++C+ C +G TC +L ++ C C Y GR CS
Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 327
Query: 474 LDVDDCAPRPCTNGGECV----DLLNAYRCICPVGFSGTNCE 511
+ C + C N G C+ D + + C+CP G++G+ CE
Sbjct: 328 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 369
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1033 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1083
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1084 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1143
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1144 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1203
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1204 LNKFQCLCDVAFAGERCEVDLADD 1227
Score = 140 bits (339), Expect = 2e-32
Identities = 86/288 (29%), Positives = 117/288 (40%), Gaps = 38/288 (13%)
Query: 409 CVNAAACNNTAGGYSCAC--LAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD--FHCAC 463
C N + C + + C+C A +DC+ D C + C ATC++ + F C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY+G C + C C +GG C CICP G++G CE D D CA SPC
Sbjct: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQ 158
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NGA C Y C C PG+ G++C E + CA C N TC+ E
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCDL--------------EVDECASDPCKNEATCLNE 204
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC--------------LPSAL-- 627
G + + Q+ G C LPS+
Sbjct: 205 IGRY-TCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 628 --PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 311
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1035 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1093
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1094 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1154 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1199
Query: 580 C 580
C
Sbjct: 1200 C 1200
Score = 129 bits (311), Expect = 6e-29
Identities = 100/348 (28%), Positives = 134/348 (38%), Gaps = 63/348 (18%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKH-GYCNGSSW--DCTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+H G C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDR---GWGGXXXXXXXXXXASGPCLHGASCRD--------------------HLDGFT 377
C G+ G S PC C + G+
Sbjct: 211 ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 270
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC------LAGWT 431
C C G+TG C EDV+ECS PC N C N G Y+C C +
Sbjct: 271 CICQPGFTGIHCEEDVNECSS--------NPCQNGGTCENLPGNYTCHCPFDNLSRTFYG 322
Query: 432 GRDCETNVDDCT-GQCLHGATCIDLVDD----FHCACAAGYAGRTCSL 474
GRDC + CT QCL+ TCI D F C C +GY G C +
Sbjct: 323 GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1023 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1081
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1082 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1128 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1185
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1186 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1222
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1031 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1087
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1088 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1197
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1198 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1109
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1110 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1224
Score = 85.8 bits (203), Expect = 7e-16
Identities = 64/237 (27%), Positives = 90/237 (37%), Gaps = 28/237 (11%)
Query: 435 CETNVDDC-TGQCLHGATCIDLVDDFHCACA--AGYAGRTCSLDVDDCAPRPCTNGGECV 491
C N C + C + +TC D D C+C+ A + C D C PC CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 492 DL--LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+ ++ C CP G+SGT CE C + C +G C+ C C G+ G+ C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 550 QRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++ E CA C NG C ++G
Sbjct: 147 -------------IDHDE-CASSPCQNGAVC--QDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGC---REGRTGALCELSLDLCGSSPCRNGGRCV 663
+A TCL + C C G TGA CE+ L+ C S+PC++ G CV
Sbjct: 191 ASDPCKNEA--TCLNEI--GRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECV 243
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/220 (22%), Positives = 76/220 (34%), Gaps = 27/220 (12%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC---VAGWTGETCAV 684
+D C S PC+N C+ G + C C +G+TG C +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEI 226
Score = 66.9 bits (156), Expect = 3e-10
Identities = 46/177 (25%), Positives = 59/177 (33%), Gaps = 16/177 (9%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
C + C + C N + C D C C+ T N K C + + C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLD-------KDCDNM---KDPC 74
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
C TCV G + Q GG C + P
Sbjct: 75 FSNPCQGSATCVNTPGE--RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP 132
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE+ D C SSPC+NG C G + C CV G+ G C + V
Sbjct: 133 --VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 784 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 842
Query: 506 SG 507
+G
Sbjct: 843 NG 844
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 830
Query: 532 QSDYYC 537
+ C
Sbjct: 831 LQGFEC 836
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1039 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1095
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1096 GVNCEVDI 1103
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1081 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1134
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1193
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1194 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1221
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 764 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 820
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 821 CPHGAQCQPVLQGFECIANAVFNGQS 846
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1026 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1066
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 781 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 831
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 832 QGFECIANAVFNGQ 845
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 777 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 832
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 833 GFECIANAVFNG 844
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 602
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 773 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 812
Score = 36.3 bits (80), Expect = 0.54
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 617 QAGGTCLPSALPPGWACGC---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGS 666
Q GGTC LP + C C RT G C L C C N G C+ G
Sbjct: 295 QNGGTC--ENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 352
Query: 667 GWWMCECVAGWTGETCAV 684
+ C C +G+TG C +
Sbjct: 353 HGFSCLCPSGYTGSLCEI 370
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 595
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 779 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 810
>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
(alternative protein) protein.
Length = 1294
Score = 188 bits (457), Expect = 1e-46
Identities = 104/337 (30%), Positives = 152/337 (45%), Gaps = 45/337 (13%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--CERVDNPCAPQPC-AHGT 328
C+++ C ++ CQ+ TC++ + D C C++ + +D C+ + +PC PC T
Sbjct: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C R F C C G+ G C HG C C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ-CL 447
C D DEC A PC N A C + GYSC C+ G+ GR C+ VD+C C
Sbjct: 145 CEIDHDEC--------ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 448 HGATCIDLVDDFHCACA---AGYAGRTCSLDVDDCAPRPCTNGGECVDL----------- 493
+ ATC++ + + C C +GY G C +D+++C PC + GECV+L
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITG 256
Query: 494 ---------LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
+ Y CIC GF+G +CE+D + C+ +PC NG C +Y CHC +
Sbjct: 257 LPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP--FD 314
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ T RD CS ++ C C N GTC+
Sbjct: 315 NLSRTFYGGRD---CSDIL---LGCTHQQCLNNGTCI 345
Score = 173 bits (420), Expect = 3e-42
Identities = 106/345 (30%), Positives = 145/345 (42%), Gaps = 46/345 (13%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
L + CQ CK + + C+ N CD + C ++ PCQ TC NT ++
Sbjct: 35 LSNSCQNNSTCKD-FSKDNDCSCSDTANNLDKDCDNMKDPCFSN-PCQGSATCVNTPGER 92
Query: 299 YF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
F C+C G+SG CE C C HG C C G+ G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 358 XASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +GA C+D +DG++C C G+ G C +VDEC A PC N A C N
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--------ASDPCKNEATCLN 203
Query: 418 TAGGYSCAC---LAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD--------------F 459
G Y+C C +G+TG CE ++++C C C++L + +
Sbjct: 204 EIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 460 H------CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG------FSG 507
H C C G+ G C DV++C+ PC NGG C +L Y C CP + G
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 323
Query: 508 TNCEDDRDHCAGSPCGNGAACYT----AQSDYYCHCAPGWTGKNC 548
+C D C C N C Q + C C G+TG C
Sbjct: 324 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 368
Score = 151 bits (367), Expect = 9e-36
Identities = 73/229 (31%), Positives = 103/229 (44%), Gaps = 19/229 (8%)
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXX 352
N ++ F + + C ++ N C PC HG + + C+C GW G
Sbjct: 1006 NKPQEEQFLKISTNSVVTGCLQL-NVCNSNPCLHGG-NCEDIYSSYHCSCPLGWSGKHCE 1063
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
S PC+HG +C D + + C C G+TG C D+D C C N
Sbjct: 1064 LNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ--------CANG 1114
Query: 413 AACNNTAGGYSCACLAGWTGRDCETN---VDDCTGQ-----CLHGATCIDLVDDFHCACA 464
A C + GYSC C +TG+ C + C + C +G C + + C C
Sbjct: 1115 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1174
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
G+ G C D+D+CA PC NGG C DLLN ++C+C V F+G CE D
Sbjct: 1175 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223
Score = 151 bits (365), Expect = 2e-35
Identities = 87/282 (30%), Positives = 130/282 (46%), Gaps = 33/282 (11%)
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
S+ C C + G +C+ + CG + CQHGG C P C C G++G CE +
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQD-PIYPVCICPAGYAGRFCEIDHD 150
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
CA PC +G G G++C C G+ G AS PC + A+C + + +T
Sbjct: 151 ECASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 378 CECA---DGWTGPACAEDVDECSGRSMTEGALGPCVNAAA--------------CNNTAG 420
C C G+TG C D++EC+ G CV ++ + A
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECNSNPCQSN--GECVELSSEKQYGRITGLPSSFSYHEAS 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAG------YAGRTCS 473
GY C C G+TG CE +V++C+ C +G TC +L ++ C C Y GR CS
Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 327
Query: 474 LDVDDCAPRPCTNGGECV----DLLNAYRCICPVGFSGTNCE 511
+ C + C N G C+ D + + C+CP G++G+ CE
Sbjct: 328 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 369
Score = 151 bits (365), Expect = 2e-35
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 17/204 (8%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 1033 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--------PCIHGN-CSDRV 1083
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCS---LD 475
Y C C G+TG +CE ++D+C QC +GATCI + + C C + G+ C L
Sbjct: 1084 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1143
Query: 476 VDDCAPRP----CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C C NGG C + +C+C GF+G CE D D CA PC NG C
Sbjct: 1144 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1203
Query: 532 QSDYYCHCAPGWTGKNCTQRAARD 555
+ + C C + G+ C A D
Sbjct: 1204 LNKFQCLCDVAFAGERCEVDLADD 1227
Score = 140 bits (339), Expect = 2e-32
Identities = 86/288 (29%), Positives = 117/288 (40%), Gaps = 38/288 (13%)
Query: 409 CVNAAACNNTAGGYSCAC--LAGWTGRDCETNVDDC-TGQCLHGATCIDLVDD--FHCAC 463
C N + C + + C+C A +DC+ D C + C ATC++ + F C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 464 AAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG 523
GY+G C + C C +GG C CICP G++G CE D D CA SPC
Sbjct: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQ 158
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NGA C Y C C PG+ G++C E + CA C N TC+ E
Sbjct: 159 NGAVCQDGIDGYSCFCVPGYQGRHCDL--------------EVDECASDPCKNEATCLNE 204
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC--------------LPSAL-- 627
G + + Q+ G C LPS+
Sbjct: 205 IGRY-TCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 263
Query: 628 --PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G+ C C+ G TG CE ++ C S+PC+NGG C G + C C
Sbjct: 264 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 311
Score = 135 bits (326), Expect = 8e-31
Identities = 61/181 (33%), Positives = 86/181 (47%), Gaps = 23/181 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 1035 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 1093
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 1094 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C Q++ C C PG+TG+ C ++ + CA C NGG
Sbjct: 1154 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE--------------KDIDECASDPCVNGGL 1199
Query: 580 C 580
C
Sbjct: 1200 C 1200
Score = 129 bits (311), Expect = 6e-29
Identities = 100/348 (28%), Positives = 134/348 (38%), Gaps = 63/348 (18%)
Query: 171 NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGD-- 228
N+TC F + D + DK C DN + P C + + PG+
Sbjct: 42 NSTCKDFSKDNDCSCS--DTANNLDKDC------DNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 229 --CDCRPGWRGELCSQCQPYPG---CKH-GYCNGSSW--DCTCDTNWGGILCDQDLNYCG 280
C C PG+ G +C G C+H G C+ C C + G C+ D + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTC 340
+ PCQ+G C++ D Y C C G+ G C+ + CA PC + L R +TC
Sbjct: 154 S-SPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-YTC 210
Query: 341 TCDR---GWGGXXXXXXXXXXASGPCLHGASCRD--------------------HLDGFT 377
C G+ G S PC C + G+
Sbjct: 211 ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 270
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC------LAGWT 431
C C G+TG C EDV+ECS PC N C N G Y+C C +
Sbjct: 271 CICQPGFTGIHCEEDVNECSS--------NPCQNGGTCENLPGNYTCHCPFDNLSRTFYG 322
Query: 432 GRDCETNVDDCT-GQCLHGATCIDLVDD----FHCACAAGYAGRTCSL 474
GRDC + CT QCL+ TCI D F C C +GY G C +
Sbjct: 323 GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370
Score = 117 bits (282), Expect = 2e-25
Identities = 66/217 (30%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 1023 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1081
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXX 590
+ Y+C C PG+TG NC + + C CANG TC+ +
Sbjct: 1082 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCISHTNGYSCL 1127
Query: 591 XXXXXXXXXXDSX---XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
GG C + C CR G TG CE
Sbjct: 1128 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKD 1185
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
+D C S PC NGG C + C C + GE C V
Sbjct: 1186 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1222
Score = 107 bits (257), Expect = 2e-22
Identities = 61/209 (29%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 1031 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 1087
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 1088 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ C +G +C + C C G+TG C +D+DEC A PCVN
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------ASDPCVNG 1197
Query: 413 AACNNTAGGYSCACLAGWTGRDCETNVDD 441
C + + C C + G CE ++ D
Sbjct: 1198 GLCQDLLNKFQCLCDVAFAGERCEVDLAD 1226
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/177 (29%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1109
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCE--RVDNPCAPQPCAHGTCSLAGTTRGFT- 339
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 1110 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1167
Query: 340 ---CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
C C G+ G AS PC++G C+D L+ F C C + G C D+
Sbjct: 1168 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1224
Score = 85.8 bits (203), Expect = 7e-16
Identities = 64/237 (27%), Positives = 90/237 (37%), Gaps = 28/237 (11%)
Query: 435 CETNVDDC-TGQCLHGATCIDLVDDFHCACA--AGYAGRTCSLDVDDCAPRPCTNGGECV 491
C N C + C + +TC D D C+C+ A + C D C PC CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 492 DL--LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+ ++ C CP G+SGT CE C + C +G C+ C C G+ G+ C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 550 QRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++ E CA C NG C ++G
Sbjct: 147 -------------IDHDE-CASSPCQNGAVC--QDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGC---REGRTGALCELSLDLCGSSPCRNGGRCV 663
+A TCL + C C G TGA CE+ L+ C S+PC++ G CV
Sbjct: 191 ASDPCKNEA--TCLNEI--GRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECV 243
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/220 (22%), Positives = 76/220 (34%), Gaps = 27/220 (12%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
C+ + C C N C D C C + + C++ +D C +PC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 530 TAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C C PG++G C C + C +GG C ++
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGS--------------CGKNSCQHGGICHQDP--- 129
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS 647
Q G C G++C C G G C+L
Sbjct: 130 -IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLE 186
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC---VAGWTGETCAV 684
+D C S PC+N C+ G + C C +G+TG C +
Sbjct: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEI 226
Score = 66.9 bits (156), Expect = 3e-10
Identities = 46/177 (25%), Positives = 59/177 (33%), Gaps = 16/177 (9%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
C + C + C N + C D C C+ T N K C + + C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLD-------KDCDNM---KDPC 74
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
C TCV G + Q GG C + P
Sbjct: 75 FSNPCQGSATCVNTPGE--RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP 132
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE+ D C SSPC+NG C G + C CV G+ G C + V
Sbjct: 133 --VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 784 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 842
Query: 506 SG 507
+G
Sbjct: 843 NG 844
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 830
Query: 532 QSDYYC 537
+ C
Sbjct: 831 LQGFEC 836
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 1039 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 1095
Query: 679 GETCAVRV 686
G C V +
Sbjct: 1096 GVNCEVDI 1103
Score = 48.4 bits (110), Expect = 1e-04
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 26/149 (17%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTHGRC---DRPGDCDCRPGWRG 237
D+ Y CT C PG+ G NCE + C+ C C C + G
Sbjct: 1081 DRVAAYHCT------CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1134
Query: 238 ELCSQCQ-PYPGCKH----------GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
+ C Q + P C + G C + C C + G C++D++ C + +P
Sbjct: 1135 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS-DP 1193
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
C +GG C++ +++ C C F+G CE
Sbjct: 1194 CVNGGLCQDLL-NKFQCLCDVAFAGERCE 1221
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 764 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 820
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 821 CPHGAQCQPVLQGFECIANAVFNGQS 846
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 1026 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1066
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 781 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 831
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 832 QGFECIANAVFNGQ 845
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 777 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 832
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 833 GFECIANAVFNG 844
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 602
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 773 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 812
Score = 36.3 bits (80), Expect = 0.54
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 617 QAGGTCLPSALPPGWACGC---REGRT---GALCELSLDLCGSSPCRNGGRCV----GGS 666
Q GGTC LP + C C RT G C L C C N G C+ G
Sbjct: 295 QNGGTC--ENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 352
Query: 667 GWWMCECVAGWTGETCAV 684
+ C C +G+TG C +
Sbjct: 353 HGFSCLCPSGYTGSLCEI 370
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 562 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 595
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 779 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 810
>AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein.
Length = 291
Score = 180 bits (438), Expect = 2e-44
Identities = 92/266 (34%), Positives = 121/266 (45%), Gaps = 16/266 (6%)
Query: 285 CQHGGTCENTAPDQYF-CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR----GFT 339
C G C + F C C E + G CE D C +PC + + + FT
Sbjct: 36 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFT 94
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C G+ G PC +GA+C L GFTC+C +G+ G AC E VD C
Sbjct: 95 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC--- 151
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD 458
A PC N C ++C C G+TG C +D C C HG TC +
Sbjct: 152 -----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTS 205
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C GY G C + ++C PC N C DL+N Y C+C + GT+CE +D CA
Sbjct: 206 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 265
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWT 544
C NGA C + + C CAPG+T
Sbjct: 266 NVSCLNGATCDSDGLNGTCICAPGFT 291
Score = 155 bits (375), Expect = 1e-36
Identities = 93/282 (32%), Positives = 128/282 (45%), Gaps = 27/282 (9%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---CQPYPGCKHGYC 254
C+PG N + K C T + C C + G C + CQ P + C
Sbjct: 24 CVPGESHANDLECSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASC 81
Query: 255 -------NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
+GS++ C C + G LC ++YC +PC++G TC ++ + C+C EG+
Sbjct: 82 IDANEKQDGSNFTCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSL-SGFTCQCPEGY 139
Query: 308 SGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G CE +PCA PC +GTC + G FTC C G+ G A PC HG
Sbjct: 140 FGSACEEKVDPCASSPCQNNGTCYVDGV--HFTCNCSPGFTGPTCAQLIDFCALSPCAHG 197
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
+CR + C C G+ G C E+ +EC PC+NAA C + GY C C
Sbjct: 198 -TCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVC 248
Query: 427 LAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY 467
LA + G CE D C CL+GATC + C CA G+
Sbjct: 249 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGF 290
Score = 149 bits (362), Expect = 4e-35
Identities = 85/261 (32%), Positives = 118/261 (45%), Gaps = 32/261 (12%)
Query: 327 GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDG--FTCECA 381
G C+ + F+CTC+ + G PC + ASC D DG FTC C
Sbjct: 40 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRK-PCQNNASCIDANEKQDGSNFTCVCL 98
Query: 382 DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD 441
G+TG C +D C L PC N A C ++ G++C C G+ G CE VD
Sbjct: 99 PGYTGELCQSKIDYC--------ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDP 150
Query: 442 CTGQ-CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + TC +D V F C C+ G+ G TC+ +D CA PC +G C + +Y+C
Sbjct: 151 CASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKC 208
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 209 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL--------- 259
Query: 560 SVLVEESERCAEGMCANGGTC 580
+ CA C NG TC
Sbjct: 260 -----YKDPCANVSCLNGATC 275
Score = 128 bits (308), Expect = 1e-28
Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 28/263 (10%)
Query: 422 YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVD-----DFHCACAAGYAGRTCSLD 475
+SC C + G CE D C + C + A+CID + +F C C GY G C
Sbjct: 51 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 109
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+D C PC NG C+ L+ + C CP G+ G+ CE+ D CA SPC N CY +
Sbjct: 110 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 169
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C+C+PG+TG C Q C++ CA G C + GT S++
Sbjct: 170 TCNCSPGFTGPTCAQLI----DFCAL-----SPCAHGTCRSVGT------SYKCLCDPGY 214
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ TC L G+ C C G CEL D C +
Sbjct: 215 HGLYCEEEYNECLSAPCLNAA----TCRD--LVNGYECVCLAEYKGTHCELYKDPCANVS 268
Query: 656 CRNGGRCVGGSGWWMCECVAGWT 678
C NG C C C G+T
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFT 291
Score = 97.1 bits (231), Expect = 3e-19
Identities = 60/229 (26%), Positives = 85/229 (37%), Gaps = 27/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA-----YRCICPVGFSGTNCEDD 513
F C C Y G C + D C +PC N C+D + C+C G++G C+
Sbjct: 51 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 109
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
D+C PC NGA C ++ S + C C G+ G C ++ + CA
Sbjct: 110 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKV--------------DPCASSP 155
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N GTC + A GTC ++ + C
Sbjct: 156 CQNNGTCYVD-----GVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTC--RSVGTSYKC 208
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C G G CE + C S+PC N C + C C+A + G C
Sbjct: 209 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 257
Score = 72.1 bits (169), Expect = 9e-12
Identities = 57/207 (27%), Positives = 78/207 (37%), Gaps = 31/207 (14%)
Query: 484 CTNGGECVDLLN--AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ-----SDYY 536
C+ G+C + + C C + GT CE+ D C PC N A+C A S++
Sbjct: 36 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 94
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C PG+TG+ C + + C C NG TC+ +
Sbjct: 95 CVCLPGYTGELCQSKI--------------DYCILDPCRNGATCISSLSGF----TCQCP 136
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC 656
S Q GTC + + C C G TG C +D C SPC
Sbjct: 137 EGYFGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPC 194
Query: 657 RNGG-RCVGGSGWWMCECVAGWTGETC 682
+G R VG S + C C G+ G C
Sbjct: 195 AHGTCRSVGTS--YKCLCDPGYHGLYC 219
Score = 66.1 bits (154), Expect = 6e-10
Identities = 50/181 (27%), Positives = 66/181 (36%), Gaps = 24/181 (13%)
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+ C H C C T S+ + C C + G C + A RK C +
Sbjct: 22 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC----QN 77
Query: 566 SERCAEGMCANGG---TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C + G TCV G D + G TC
Sbjct: 78 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC-------------RNGATC 124
Query: 623 LPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ S G+ C C EG G+ CE +D C SSPC+N G C + C C G+TG TC
Sbjct: 125 ISSL--SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 182
Query: 683 A 683
A
Sbjct: 183 A 183
Score = 56.8 bits (131), Expect = 4e-07
Identities = 21/56 (37%), Positives = 29/56 (51%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+ C C G TG LC+ +D C PCRNG C+ + C+C G+ G C +V
Sbjct: 93 FTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKV 148
Score = 46.0 bits (104), Expect = 7e-04
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS-----GWWMCECV 674
G C ++C C E G CE D C PC+N C+ + + C C+
Sbjct: 40 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 98
Query: 675 AGWTGETCAVRV 686
G+TGE C ++
Sbjct: 99 PGYTGELCQSKI 110
>AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 377
Score = 173 bits (420), Expect = 3e-42
Identities = 85/243 (34%), Positives = 111/243 (45%), Gaps = 19/243 (7%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C+ G G C C HG C G C C PGW G C +C PGC+HG C+
Sbjct: 15 CILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-Q 73
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
W C C + W D + C T PCQ+GG C +Y C C GF G DCER
Sbjct: 74 PWQCICHSGWA------DEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG 127
Query: 318 PC--APQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
PC A PC + G C G FTC C G+ G PC +GA+C D +
Sbjct: 128 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 187
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
+ F+C C +G+ G C ++D+C+ R PC A C + + C C +G+ G+
Sbjct: 188 NRFSCLCPEGFAGRFCTINLDDCASR--------PCQRGARCRDRVHDFDCLCPSGYGGK 239
Query: 434 DCE 436
CE
Sbjct: 240 TCE 242
Score = 162 bits (394), Expect = 5e-39
Identities = 88/239 (36%), Positives = 115/239 (48%), Gaps = 31/239 (12%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRG 337
C +H HG C APD CRC G+ G+ CER C P C HGTC +
Sbjct: 29 CSSHCDLAHG--C--CAPDGS-CRCDPGWEGLHCER----CVRMPGCQHGTCH-----QP 74
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDEC 396
+ C C GW PC +G C G + C C G+ G C C
Sbjct: 75 WQCICHSGWADEHICTT-----QSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPC 129
Query: 397 SGRSMTEGALGPCVNAAACNNTAG---GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATC 452
E A PC N C + G ++C CL G+ G CE NVDDC + C +GATC
Sbjct: 130 ------EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATC 183
Query: 453 IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+D ++ F C C G+AGR C++++DDCA RPC G C D ++ + C+CP G+ G CE
Sbjct: 184 LDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCE 242
Score = 149 bits (361), Expect = 5e-35
Identities = 85/242 (35%), Positives = 107/242 (44%), Gaps = 32/242 (13%)
Query: 314 RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
R D+ + AHG C+ G+ C CD GW G C HG +C
Sbjct: 25 RADDCSSHCDLAHGCCAPDGS-----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQP- 74
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTG 432
+ C C GW D C+ +S PC N C GG Y C CL G+ G
Sbjct: 75 --WQCICHSGWA------DEHICTTQS-------PCQNGGQCMYDGGGEYHCVCLPGFHG 119
Query: 433 RDCETNVDDCT---GQCLHGATCID---LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTN 486
RDCE C C +G C D +F C C G+ G C ++VDDC RPC N
Sbjct: 120 RDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCAN 179
Query: 487 GGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
G C+D +N + C+CP GF+G C + D CA PC GA C D+ C C G+ GK
Sbjct: 180 GATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGK 239
Query: 547 NC 548
C
Sbjct: 240 TC 241
Score = 147 bits (356), Expect = 2e-34
Identities = 76/211 (36%), Positives = 100/211 (47%), Gaps = 14/211 (6%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGE-LCSQCQP 245
H C PDG C PGW+G +CE+ V GC HG C +P C C GW E +C+ P
Sbjct: 37 HGCCAPDGSCRCDPGWEGLHCERCVRMPGCQ--HGTCHQPWQCICHSGWADEHICTTQSP 94
Query: 246 YPGCKHG----YCNGSSWDCTCDTNWGGILCDQDLNYC-GTHEPCQHGGTCENTA--PDQ 298
C++G Y G + C C + G C++ C PC++GG C++
Sbjct: 95 ---CQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN 151
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
+ CRC GF G CE + C +PCA+G L G R F+C C G+ G
Sbjct: 152 FTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINR-FSCLCPEGFAGRFCTINLDDC 210
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
AS PC GA CRD + F C C G+ G C
Sbjct: 211 ASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 241
Score = 128 bits (309), Expect = 1e-28
Identities = 80/239 (33%), Positives = 105/239 (43%), Gaps = 31/239 (12%)
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C + HG C C CD W G+ C++ + G CQHG TC P Q C
Sbjct: 29 CSSHCDLAHGCC-APDGSCRCDPGWEGLHCERCVRMPG----CQHG-TCHQ--PWQ--CI 78
Query: 303 CAEGFSGVDCERVDNPCAPQ-PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX--XXA 359
C G++ ++ C Q PC +G + + C C G+ G A
Sbjct: 79 CHSGWAD------EHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQA 132
Query: 360 SGPCLHGASCRDHLD---GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
PC +G C+D FTC C G+ G C +VD+C R PC N A C
Sbjct: 133 GSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMR--------PCANGATCL 184
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ +SC C G+ GR C N+DDC + C GA C D V DF C C +GY G+TC L
Sbjct: 185 DGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 243
Score = 97.5 bits (232), Expect = 2e-19
Identities = 53/151 (35%), Positives = 68/151 (45%), Gaps = 16/151 (10%)
Query: 409 CVNAAACNNTA--GGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVDDFHCACA 464
CV C + + C C +GW T C GQC++ D ++HC C
Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWADEHICTTQSPCQNGGQCMY-----DGGGEYHCVCL 114
Query: 465 AGYAGRTCSLDVDDC--APRPCTNGGECVD----LLNAYRCICPVGFSGTNCEDDRDHCA 518
G+ GR C C A PC NGG+C D LN + C C VGF G CE + D C
Sbjct: 115 PGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN-FTCRCLVGFVGARCEVNVDDCL 173
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
PC NGA C + + C C G+ G+ CT
Sbjct: 174 MRPCANGATCLDGINRFSCLCPEGFAGRFCT 204
Score = 93.1 bits (221), Expect = 4e-18
Identities = 71/258 (27%), Positives = 101/258 (39%), Gaps = 32/258 (12%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C+ G G+ DDC+ C C D C C G+ G C + C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCC--APDGSCRCDPGWEGLHC----ERCVRMPGC 66
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYYCHCAPGWT 544
G C ++CIC G++ D+ SPC NG C Y +Y+C C PG+
Sbjct: 67 QHGTCHQ---PWQCICHSGWA-----DEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFH 118
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXX 604
G++C ++A C A C NGG C ++G + +
Sbjct: 119 GRDCERKAG----PCEQ--------AGSPCRNGGQCQDDQG-FALNFTCRCLVGFVGARC 165
Query: 605 XXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG 664
G TCL ++C C EG G C ++LD C S PC+ G RC
Sbjct: 166 EVNVDDCLMRPCANGATCLDGI--NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRD 223
Query: 665 GSGWWMCECVAGWTGETC 682
+ C C +G+ G+TC
Sbjct: 224 RVHDFDCLCPSGYGGKTC 241
Score = 62.9 bits (146), Expect = 5e-09
Identities = 49/186 (26%), Positives = 66/186 (35%), Gaps = 19/186 (10%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR----DRKTC---------SV 561
D C+ S C C D C C PGW G +C +R R TC S
Sbjct: 27 DDCS-SHCDLAHGC--CAPDGSCRCDPGWEGLHC-ERCVRMPGCQHGTCHQPWQCICHSG 82
Query: 562 LVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT 621
+E + C NGG C+ + G D + GG
Sbjct: 83 WADEHICTTQSPCQNGGQCMYDGGG-EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQ 141
Query: 622 CLPS-ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
C + C C G GA CE+++D C PC NG C+ G + C C G+ G
Sbjct: 142 CQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGR 201
Query: 681 TCAVRV 686
C + +
Sbjct: 202 FCTINL 207
Score = 58.8 bits (136), Expect = 9e-08
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 194 GDKHC--LPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG-----DCDCRPGWRGELCS 241
G+ HC LPG+ G +CE+ C++ P G+C D G C C G+ G C
Sbjct: 107 GEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE 166
Query: 242 ----QCQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA 295
C P C +G + + C C + G C +L+ C + PCQ G C +
Sbjct: 167 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR-PCQRGARCRDRV 225
Query: 296 PDQYFCRCAEGFSGVDCERV 315
D + C C G+ G CE V
Sbjct: 226 HD-FDCLCPSGYGGKTCELV 244
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
protein.
Length = 1529
Score = 171 bits (417), Expect = 8e-42
Identities = 87/246 (35%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
NPC PC + GTC+ + + CTC G+ G S PC HG +C
Sbjct: 920 NPCLSNPCKNDGTCN-SDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGE 978
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF C CADG+ G C +VD+C C N + C + Y+C C +TG
Sbjct: 979 EDGFWCICADGFEGENCEVNVDDCEDND--------CENNSTCVDGINNYTCLCPPEYTG 1030
Query: 433 RDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
CE +D C C H + CI F C C GY G C +D DDC C NG
Sbjct: 1031 ELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAH 1090
Query: 490 CVDLLNAYRCICPVGFSGTNCE-------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C D +N Y CICP G+SG CE C C NGA C ++ C C PG
Sbjct: 1091 CTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPG 1150
Query: 543 WTGKNC 548
+ G+ C
Sbjct: 1151 YQGEKC 1156
Score = 159 bits (385), Expect = 6e-38
Identities = 80/238 (33%), Positives = 110/238 (46%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSL-AGTTRGFTCT 341
PC++ GTC + D Y C C GF G DC+ + C PC H GTC L G GF C
Sbjct: 926 PCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCI 985
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + ++C D ++ +TC C +TG C E +D C+
Sbjct: 986 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCA---- 1041
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFH 460
L PC + + C T G+ C C G+ G C+ + DDC +C +GA C D V+ +
Sbjct: 1042 --QDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT 1099
Query: 461 CACAAGYAGRTCSLDVDDCAPR-------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C GY+G C PR C NG +C+ +N C C G+ G CE
Sbjct: 1100 CICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 100 bits (240), Expect = 2e-20
Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 35/256 (13%)
Query: 446 CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC---VDLLNAYRCIC 501
C + TC D VD + C C G+ G+ C + + C PC +GG C + + CIC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCIC 986
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR---AARDRKT 558
GF G NCE + D C + C N + C ++Y C C P +TG+ C ++ A+D
Sbjct: 987 ADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNP 1046
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
C + +C + G C G D
Sbjct: 1047 C----QHDSKCI--LTPKGFKCDCTPG----YVGEHCDIDFDDCQDNKCKNGAHCTDAVN 1096
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDL-------CGSSPCRNGGRCVGGSGWWMC 671
G TC+ C EG +G CE S + C + C+NG +C+ +C
Sbjct: 1097 GYTCI-----------CPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPIC 1145
Query: 672 ECVAGWTGETCAVRVS 687
+C+ G+ GE C VS
Sbjct: 1146 QCLPGYQGEKCEKLVS 1161
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 240 CSQCQPYPGCKHGYCNGSS---WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
C C C HG C SS + C C W G LCDQ N C H GTC
Sbjct: 1333 CEPCHKKV-CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPINA 1390
Query: 297 DQYFCRCAEGFSGVDCERVD---NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C EG GV C+ + NPC C HG C L+G + + C C G+ G
Sbjct: 1391 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPY-CECSSGYTG 1444
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 18/127 (14%)
Query: 199 LPGWQGDNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYP----GCKHGY 253
LPG + C K VC G C P+ C+C+ GW G LC Q P C HG
Sbjct: 1330 LPGCEP--CHKKVCAHGTCQPSS---QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT 1384
Query: 254 C---NGSSWDCTCDTNWGGILCDQD---LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
C N S+ C C GG+LCD++ N C + C+HG C + Q +C C+ G+
Sbjct: 1385 CLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHG-KCRLSGLGQPYCECSSGY 1442
Query: 308 SGVDCER 314
+G C+R
Sbjct: 1443 TGDSCDR 1449
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/119 (33%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG GFTCEC +GW GP C + D C G G P +NA +
Sbjct: 1341 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLP-INAFS------- 1392
Query: 422 YSCACLAGWTGRDCETNVD---DCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
YSC CL G G C+ D C +C HG + + +C C++GY G +C ++
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C + ++ G++C C GW G C+ +D C G +C+HG TC+ + + C C
Sbjct: 1341 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPINAFSYSCKCLE 1399
Query: 466 GYAGRTCSLDVD---DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
G+ G C + D C C +G + L C C G++G +C D C G
Sbjct: 1400 GHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC-DREISCRGERI 1458
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNC 548
+ AAC T + C G G C
Sbjct: 1459 RDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 62.5 bits (145), Expect = 7e-09
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ-----CQPYP 247
C G++G+NCE V C++ + C D + C C P + GELC + Q
Sbjct: 986 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLN 1045
Query: 248 GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H C + C C + G CD D + C ++ C++G C + A + Y C C
Sbjct: 1046 PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNK-CKNGAHCTD-AVNGYTCICP 1103
Query: 305 EGFSGVDCERVDNPCAPQ--PCAHGTC 329
EG+SG+ CE P+ PC + C
Sbjct: 1104 EGYSGLFCEFSPPMVLPRTSPCDNFDC 1130
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/171 (24%), Positives = 63/171 (36%), Gaps = 20/171 (11%)
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C +PC N C + D+Y C C G+ G++C V + C C
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDC-----------DVPIHA---CISNPCK 967
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTC +EG + TC+ + C C
Sbjct: 968 HGGTCHLKEGE-EDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLC 1024
Query: 636 REGRTGALCELSLDLCGS--SPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
TG LCE LD C +PC++ +C+ + C+C G+ GE C +
Sbjct: 1025 PPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1075
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELSLDL---CGSSPCRNGGRCVGGSGWWMCECVA 675
GTCLP +A ++C C EG G LC+ DL C + C++G + G G CEC +
Sbjct: 1383 GTCLPINAF--SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSS 1440
Query: 676 GWTGETCAVRVS 687
G+TG++C +S
Sbjct: 1441 GYTGDSCDREIS 1452
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 24/139 (17%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC---DRPGDCDCRPGWRGELCS----QCQPY 246
C P + G+ CE+ + C + +P +C + CDC PG+ GE C CQ
Sbjct: 1024 CPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDN 1083
Query: 247 PGCKHG-YCNGS--SWDCTCDTNWGGILCDQD-------LNYCGTHEPCQHGGTCENTAP 296
CK+G +C + + C C + G+ C+ + C + CQ+G C
Sbjct: 1084 K-CKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCI-VRI 1140
Query: 297 DQYFCRCAEGFSGVDCERV 315
++ C+C G+ G CE++
Sbjct: 1141 NEPICQCLPGYQGEKCEKL 1159
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 618 AGGTCLPSALPPGWACGCREGRTGALC-ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
A GTC PS+ G+ C C+EG G LC + + D C + C +G + + C+C+ G
Sbjct: 1342 AHGTCQPSS-QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEG 1400
Query: 677 WTGETC 682
G C
Sbjct: 1401 HGGVLC 1406
Score = 40.7 bits (91), Expect = 0.025
Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 32/163 (19%)
Query: 178 CRPRDDKF-GHYSCTPDGDK----HCLPGWQGDNCEK----PVCKEGCHPTHGRCDRPG- 227
C P K H +C P C GW G C++ P C HG C
Sbjct: 1333 CEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC--VHGTCLPINA 1390
Query: 228 ---DCDCRPGWRGELCSQ-------CQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQ 274
C C G G LC + CQ CKHG C S C C + + G CD+
Sbjct: 1391 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHGKCRLSGLGQPYCECSSGYTGDSCDR 1449
Query: 275 DLNYCGT-----HEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+++ G ++ Q C+ T C G +G C
Sbjct: 1450 EISCRGERIRDYYQKQQGYAACQTTKKVSRL-ECRGGCAGGQC 1491
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 1/75 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSPCGNGAACYTAQSDY 535
+ C + C +G + C C G+ G C+ D C G+ C +G Y
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1393
Query: 536 YCHCAPGWTGKNCTQ 550
C C G G C +
Sbjct: 1394 SCKCLEGHGGVLCDE 1408
Score = 33.5 bits (73), Expect = 3.8
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C C +G ++Q+ + C C GW G C QR
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQR 1370
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 651 CGSSPCRNGGRCVGGS-GWWMCECVAGWTGETCAVRV 686
C S+PC+N G C ++ C C G+ G+ C V +
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPI 958
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 171 bits (417), Expect = 8e-42
Identities = 87/246 (35%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
NPC PC + GTC+ + + CTC G+ G S PC HG +C
Sbjct: 916 NPCLSNPCKNDGTCN-SDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGE 974
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF C CADG+ G C +VD+C C N + C + Y+C C +TG
Sbjct: 975 EDGFWCICADGFEGENCEVNVDDCEDND--------CENNSTCVDGINNYTCLCPPEYTG 1026
Query: 433 RDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
CE +D C C H + CI F C C GY G C +D DDC C NG
Sbjct: 1027 ELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAH 1086
Query: 490 CVDLLNAYRCICPVGFSGTNCE-------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C D +N Y CICP G+SG CE C C NGA C ++ C C PG
Sbjct: 1087 CTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPG 1146
Query: 543 WTGKNC 548
+ G+ C
Sbjct: 1147 YQGEKC 1152
Score = 159 bits (385), Expect = 6e-38
Identities = 80/238 (33%), Positives = 110/238 (46%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSL-AGTTRGFTCT 341
PC++ GTC + D Y C C GF G DC+ + C PC H GTC L G GF C
Sbjct: 922 PCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCI 981
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + ++C D ++ +TC C +TG C E +D C+
Sbjct: 982 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCA---- 1037
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFH 460
L PC + + C T G+ C C G+ G C+ + DDC +C +GA C D V+ +
Sbjct: 1038 --QDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT 1095
Query: 461 CACAAGYAGRTCSLDVDDCAPR-------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C GY+G C PR C NG +C+ +N C C G+ G CE
Sbjct: 1096 CICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1153
Score = 100 bits (240), Expect = 2e-20
Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 35/256 (13%)
Query: 446 CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC---VDLLNAYRCIC 501
C + TC D VD + C C G+ G+ C + + C PC +GG C + + CIC
Sbjct: 923 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCIC 982
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR---AARDRKT 558
GF G NCE + D C + C N + C ++Y C C P +TG+ C ++ A+D
Sbjct: 983 ADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNP 1042
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
C + +C + G C G D
Sbjct: 1043 C----QHDSKCI--LTPKGFKCDCTPG----YVGEHCDIDFDDCQDNKCKNGAHCTDAVN 1092
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDL-------CGSSPCRNGGRCVGGSGWWMC 671
G TC+ C EG +G CE S + C + C+NG +C+ +C
Sbjct: 1093 GYTCI-----------CPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPIC 1141
Query: 672 ECVAGWTGETCAVRVS 687
+C+ G+ GE C VS
Sbjct: 1142 QCLPGYQGEKCEKLVS 1157
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 240 CSQCQPYPGCKHGYCNGSS---WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
C C C HG C SS + C C W G LCDQ N C H GTC
Sbjct: 1329 CEPCHKKV-CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPINA 1386
Query: 297 DQYFCRCAEGFSGVDCERVD---NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C EG GV C+ + NPC C HG C L+G + + C C G+ G
Sbjct: 1387 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPY-CECSSGYTG 1440
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 18/127 (14%)
Query: 199 LPGWQGDNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYP----GCKHGY 253
LPG + C K VC G C P+ C+C+ GW G LC Q P C HG
Sbjct: 1326 LPGCEP--CHKKVCAHGTCQPSS---QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT 1380
Query: 254 C---NGSSWDCTCDTNWGGILCDQD---LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
C N S+ C C GG+LCD++ N C + C+HG C + Q +C C+ G+
Sbjct: 1381 CLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHG-KCRLSGLGQPYCECSSGY 1438
Query: 308 SGVDCER 314
+G C+R
Sbjct: 1439 TGDSCDR 1445
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/119 (33%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG GFTCEC +GW GP C + D C G G P +NA +
Sbjct: 1337 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLP-INAFS------- 1388
Query: 422 YSCACLAGWTGRDCETNVD---DCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
YSC CL G G C+ D C +C HG + + +C C++GY G +C ++
Sbjct: 1389 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1447
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C + ++ G++C C GW G C+ +D C G +C+HG TC+ + + C C
Sbjct: 1337 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPINAFSYSCKCLE 1395
Query: 466 GYAGRTCSLDVD---DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
G+ G C + D C C +G + L C C G++G +C D C G
Sbjct: 1396 GHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC-DREISCRGERI 1454
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNC 548
+ AAC T + C G G C
Sbjct: 1455 RDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1487
Score = 62.5 bits (145), Expect = 7e-09
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ-----CQPYP 247
C G++G+NCE V C++ + C D + C C P + GELC + Q
Sbjct: 982 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLN 1041
Query: 248 GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H C + C C + G CD D + C ++ C++G C + A + Y C C
Sbjct: 1042 PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNK-CKNGAHCTD-AVNGYTCICP 1099
Query: 305 EGFSGVDCERVDNPCAPQ--PCAHGTC 329
EG+SG+ CE P+ PC + C
Sbjct: 1100 EGYSGLFCEFSPPMVLPRTSPCDNFDC 1126
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/171 (24%), Positives = 63/171 (36%), Gaps = 20/171 (11%)
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C +PC N C + D+Y C C G+ G++C V + C C
Sbjct: 918 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDC-----------DVPIHA---CISNPCK 963
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTC +EG + TC+ + C C
Sbjct: 964 HGGTCHLKEGE-EDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLC 1020
Query: 636 REGRTGALCELSLDLCGS--SPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
TG LCE LD C +PC++ +C+ + C+C G+ GE C +
Sbjct: 1021 PPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1071
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELSLDL---CGSSPCRNGGRCVGGSGWWMCECVA 675
GTCLP +A ++C C EG G LC+ DL C + C++G + G G CEC +
Sbjct: 1379 GTCLPINAF--SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSS 1436
Query: 676 GWTGETCAVRVS 687
G+TG++C +S
Sbjct: 1437 GYTGDSCDREIS 1448
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 24/139 (17%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC---DRPGDCDCRPGWRGELCS----QCQPY 246
C P + G+ CE+ + C + +P +C + CDC PG+ GE C CQ
Sbjct: 1020 CPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDN 1079
Query: 247 PGCKHG-YCNGS--SWDCTCDTNWGGILCDQD-------LNYCGTHEPCQHGGTCENTAP 296
CK+G +C + + C C + G+ C+ + C + CQ+G C
Sbjct: 1080 K-CKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCI-VRI 1136
Query: 297 DQYFCRCAEGFSGVDCERV 315
++ C+C G+ G CE++
Sbjct: 1137 NEPICQCLPGYQGEKCEKL 1155
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 618 AGGTCLPSALPPGWACGCREGRTGALC-ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
A GTC PS+ G+ C C+EG G LC + + D C + C +G + + C+C+ G
Sbjct: 1338 AHGTCQPSS-QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEG 1396
Query: 677 WTGETC 682
G C
Sbjct: 1397 HGGVLC 1402
Score = 40.7 bits (91), Expect = 0.025
Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 32/163 (19%)
Query: 178 CRPRDDKF-GHYSCTPDGDK----HCLPGWQGDNCEK----PVCKEGCHPTHGRCDRPG- 227
C P K H +C P C GW G C++ P C HG C
Sbjct: 1329 CEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC--VHGTCLPINA 1386
Query: 228 ---DCDCRPGWRGELCSQ-------CQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQ 274
C C G G LC + CQ CKHG C S C C + + G CD+
Sbjct: 1387 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHGKCRLSGLGQPYCECSSGYTGDSCDR 1445
Query: 275 DLNYCGT-----HEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+++ G ++ Q C+ T C G +G C
Sbjct: 1446 EISCRGERIRDYYQKQQGYAACQTTKKVSRL-ECRGGCAGGQC 1487
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 1/75 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSPCGNGAACYTAQSDY 535
+ C + C +G + C C G+ G C+ D C G+ C +G Y
Sbjct: 1330 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1389
Query: 536 YCHCAPGWTGKNCTQ 550
C C G G C +
Sbjct: 1390 SCKCLEGHGGVLCDE 1404
Score = 33.5 bits (73), Expect = 3.8
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C C +G ++Q+ + C C GW G C QR
Sbjct: 1332 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQR 1366
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 651 CGSSPCRNGGRCVGGS-GWWMCECVAGWTGETCAVRV 686
C S+PC+N G C ++ C C G+ G+ C V +
Sbjct: 918 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPI 954
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 171 bits (417), Expect = 8e-42
Identities = 87/246 (35%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
NPC PC + GTC+ + + CTC G+ G S PC HG +C
Sbjct: 912 NPCLSNPCKNDGTCN-SDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGE 970
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF C CADG+ G C +VD+C C N + C + Y+C C +TG
Sbjct: 971 EDGFWCICADGFEGENCEVNVDDCEDND--------CENNSTCVDGINNYTCLCPPEYTG 1022
Query: 433 RDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
CE +D C C H + CI F C C GY G C +D DDC C NG
Sbjct: 1023 ELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAH 1082
Query: 490 CVDLLNAYRCICPVGFSGTNCE-------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C D +N Y CICP G+SG CE C C NGA C ++ C C PG
Sbjct: 1083 CTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPG 1142
Query: 543 WTGKNC 548
+ G+ C
Sbjct: 1143 YQGEKC 1148
Score = 159 bits (385), Expect = 6e-38
Identities = 80/238 (33%), Positives = 110/238 (46%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSL-AGTTRGFTCT 341
PC++ GTC + D Y C C GF G DC+ + C PC H GTC L G GF C
Sbjct: 918 PCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCI 977
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + ++C D ++ +TC C +TG C E +D C+
Sbjct: 978 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCA---- 1033
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFH 460
L PC + + C T G+ C C G+ G C+ + DDC +C +GA C D V+ +
Sbjct: 1034 --QDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT 1091
Query: 461 CACAAGYAGRTCSLDVDDCAPR-------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C GY+G C PR C NG +C+ +N C C G+ G CE
Sbjct: 1092 CICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1149
Score = 100 bits (240), Expect = 2e-20
Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 35/256 (13%)
Query: 446 CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC---VDLLNAYRCIC 501
C + TC D VD + C C G+ G+ C + + C PC +GG C + + CIC
Sbjct: 919 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCIC 978
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR---AARDRKT 558
GF G NCE + D C + C N + C ++Y C C P +TG+ C ++ A+D
Sbjct: 979 ADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNP 1038
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
C + +C + G C G D
Sbjct: 1039 C----QHDSKCI--LTPKGFKCDCTPG----YVGEHCDIDFDDCQDNKCKNGAHCTDAVN 1088
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDL-------CGSSPCRNGGRCVGGSGWWMC 671
G TC+ C EG +G CE S + C + C+NG +C+ +C
Sbjct: 1089 GYTCI-----------CPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPIC 1137
Query: 672 ECVAGWTGETCAVRVS 687
+C+ G+ GE C VS
Sbjct: 1138 QCLPGYQGEKCEKLVS 1153
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 240 CSQCQPYPGCKHGYCNGSS---WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
C C C HG C SS + C C W G LCDQ N C H GTC
Sbjct: 1325 CEPCHKKV-CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPINA 1382
Query: 297 DQYFCRCAEGFSGVDCERVD---NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C EG GV C+ + NPC C HG C L+G + + C C G+ G
Sbjct: 1383 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPY-CECSSGYTG 1436
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 18/127 (14%)
Query: 199 LPGWQGDNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYP----GCKHGY 253
LPG + C K VC G C P+ C+C+ GW G LC Q P C HG
Sbjct: 1322 LPGCEP--CHKKVCAHGTCQPSS---QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT 1376
Query: 254 C---NGSSWDCTCDTNWGGILCDQD---LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
C N S+ C C GG+LCD++ N C + C+HG C + Q +C C+ G+
Sbjct: 1377 CLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHG-KCRLSGLGQPYCECSSGY 1434
Query: 308 SGVDCER 314
+G C+R
Sbjct: 1435 TGDSCDR 1441
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/119 (33%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG GFTCEC +GW GP C + D C G G P +NA +
Sbjct: 1333 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLP-INAFS------- 1384
Query: 422 YSCACLAGWTGRDCETNVD---DCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
YSC CL G G C+ D C +C HG + + +C C++GY G +C ++
Sbjct: 1385 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1443
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C + ++ G++C C GW G C+ +D C G +C+HG TC+ + + C C
Sbjct: 1333 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPINAFSYSCKCLE 1391
Query: 466 GYAGRTCSLDVD---DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
G+ G C + D C C +G + L C C G++G +C D C G
Sbjct: 1392 GHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC-DREISCRGERI 1450
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNC 548
+ AAC T + C G G C
Sbjct: 1451 RDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1483
Score = 62.5 bits (145), Expect = 7e-09
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ-----CQPYP 247
C G++G+NCE V C++ + C D + C C P + GELC + Q
Sbjct: 978 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLN 1037
Query: 248 GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H C + C C + G CD D + C ++ C++G C + A + Y C C
Sbjct: 1038 PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNK-CKNGAHCTD-AVNGYTCICP 1095
Query: 305 EGFSGVDCERVDNPCAPQ--PCAHGTC 329
EG+SG+ CE P+ PC + C
Sbjct: 1096 EGYSGLFCEFSPPMVLPRTSPCDNFDC 1122
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/171 (24%), Positives = 63/171 (36%), Gaps = 20/171 (11%)
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C +PC N C + D+Y C C G+ G++C V + C C
Sbjct: 914 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDC-----------DVPIHA---CISNPCK 959
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTC +EG + TC+ + C C
Sbjct: 960 HGGTCHLKEGE-EDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLC 1016
Query: 636 REGRTGALCELSLDLCGS--SPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
TG LCE LD C +PC++ +C+ + C+C G+ GE C +
Sbjct: 1017 PPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1067
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELSLDL---CGSSPCRNGGRCVGGSGWWMCECVA 675
GTCLP +A ++C C EG G LC+ DL C + C++G + G G CEC +
Sbjct: 1375 GTCLPINAF--SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSS 1432
Query: 676 GWTGETCAVRVS 687
G+TG++C +S
Sbjct: 1433 GYTGDSCDREIS 1444
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 24/139 (17%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC---DRPGDCDCRPGWRGELCS----QCQPY 246
C P + G+ CE+ + C + +P +C + CDC PG+ GE C CQ
Sbjct: 1016 CPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDN 1075
Query: 247 PGCKHG-YCNGS--SWDCTCDTNWGGILCDQD-------LNYCGTHEPCQHGGTCENTAP 296
CK+G +C + + C C + G+ C+ + C + CQ+G C
Sbjct: 1076 K-CKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCI-VRI 1132
Query: 297 DQYFCRCAEGFSGVDCERV 315
++ C+C G+ G CE++
Sbjct: 1133 NEPICQCLPGYQGEKCEKL 1151
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 618 AGGTCLPSALPPGWACGCREGRTGALC-ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
A GTC PS+ G+ C C+EG G LC + + D C + C +G + + C+C+ G
Sbjct: 1334 AHGTCQPSS-QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEG 1392
Query: 677 WTGETC 682
G C
Sbjct: 1393 HGGVLC 1398
Score = 40.7 bits (91), Expect = 0.025
Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 32/163 (19%)
Query: 178 CRPRDDKF-GHYSCTPDGDK----HCLPGWQGDNCEK----PVCKEGCHPTHGRCDRPG- 227
C P K H +C P C GW G C++ P C HG C
Sbjct: 1325 CEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC--VHGTCLPINA 1382
Query: 228 ---DCDCRPGWRGELCSQ-------CQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQ 274
C C G G LC + CQ CKHG C S C C + + G CD+
Sbjct: 1383 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHGKCRLSGLGQPYCECSSGYTGDSCDR 1441
Query: 275 DLNYCGT-----HEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+++ G ++ Q C+ T C G +G C
Sbjct: 1442 EISCRGERIRDYYQKQQGYAACQTTKKVSRL-ECRGGCAGGQC 1483
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 1/75 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSPCGNGAACYTAQSDY 535
+ C + C +G + C C G+ G C+ D C G+ C +G Y
Sbjct: 1326 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1385
Query: 536 YCHCAPGWTGKNCTQ 550
C C G G C +
Sbjct: 1386 SCKCLEGHGGVLCDE 1400
Score = 33.5 bits (73), Expect = 3.8
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C C +G ++Q+ + C C GW G C QR
Sbjct: 1328 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQR 1362
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 651 CGSSPCRNGGRCVGGS-GWWMCECVAGWTGETCAVRV 686
C S+PC+N G C ++ C C G+ G+ C V +
Sbjct: 914 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPI 950
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 171 bits (417), Expect = 8e-42
Identities = 87/246 (35%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
NPC PC + GTC+ + + CTC G+ G S PC HG +C
Sbjct: 920 NPCLSNPCKNDGTCN-SDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGE 978
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF C CADG+ G C +VD+C C N + C + Y+C C +TG
Sbjct: 979 EDGFWCICADGFEGENCEVNVDDCEDND--------CENNSTCVDGINNYTCLCPPEYTG 1030
Query: 433 RDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
CE +D C C H + CI F C C GY G C +D DDC C NG
Sbjct: 1031 ELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAH 1090
Query: 490 CVDLLNAYRCICPVGFSGTNCE-------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C D +N Y CICP G+SG CE C C NGA C ++ C C PG
Sbjct: 1091 CTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPG 1150
Query: 543 WTGKNC 548
+ G+ C
Sbjct: 1151 YQGEKC 1156
Score = 159 bits (385), Expect = 6e-38
Identities = 80/238 (33%), Positives = 110/238 (46%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSL-AGTTRGFTCT 341
PC++ GTC + D Y C C GF G DC+ + C PC H GTC L G GF C
Sbjct: 926 PCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCI 985
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + ++C D ++ +TC C +TG C E +D C+
Sbjct: 986 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCA---- 1041
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFH 460
L PC + + C T G+ C C G+ G C+ + DDC +C +GA C D V+ +
Sbjct: 1042 --QDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT 1099
Query: 461 CACAAGYAGRTCSLDVDDCAPR-------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C GY+G C PR C NG +C+ +N C C G+ G CE
Sbjct: 1100 CICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 100 bits (240), Expect = 2e-20
Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 35/256 (13%)
Query: 446 CLHGATC-IDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC---VDLLNAYRCIC 501
C + TC D VD + C C G+ G+ C + + C PC +GG C + + CIC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCIC 986
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR---AARDRKT 558
GF G NCE + D C + C N + C ++Y C C P +TG+ C ++ A+D
Sbjct: 987 ADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNP 1046
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
C + +C + G C G D
Sbjct: 1047 C----QHDSKCI--LTPKGFKCDCTPG----YVGEHCDIDFDDCQDNKCKNGAHCTDAVN 1096
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDL-------CGSSPCRNGGRCVGGSGWWMC 671
G TC+ C EG +G CE S + C + C+NG +C+ +C
Sbjct: 1097 GYTCI-----------CPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPIC 1145
Query: 672 ECVAGWTGETCAVRVS 687
+C+ G+ GE C VS
Sbjct: 1146 QCLPGYQGEKCEKLVS 1161
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 240 CSQCQPYPGCKHGYCNGSS---WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
C C C HG C SS + C C W G LCDQ N C H GTC
Sbjct: 1333 CEPCHKKV-CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPINA 1390
Query: 297 DQYFCRCAEGFSGVDCERVD---NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C EG GV C+ + NPC C HG C L+G + + C C G+ G
Sbjct: 1391 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPY-CECSSGYTG 1444
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 18/127 (14%)
Query: 199 LPGWQGDNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYP----GCKHGY 253
LPG + C K VC G C P+ C+C+ GW G LC Q P C HG
Sbjct: 1330 LPGCEP--CHKKVCAHGTCQPSS---QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT 1384
Query: 254 C---NGSSWDCTCDTNWGGILCDQD---LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF 307
C N S+ C C GG+LCD++ N C + C+HG C + Q +C C+ G+
Sbjct: 1385 CLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHG-KCRLSGLGQPYCECSSGY 1442
Query: 308 SGVDCER 314
+G C+R
Sbjct: 1443 TGDSCDR 1449
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/119 (33%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG GFTCEC +GW GP C + D C G G P +NA +
Sbjct: 1341 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLP-INAFS------- 1392
Query: 422 YSCACLAGWTGRDCETNVD---DCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
YSC CL G G C+ D C +C HG + + +C C++GY G +C ++
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C + ++ G++C C GW G C+ +D C G +C+HG TC+ + + C C
Sbjct: 1341 CAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPINAFSYSCKCLE 1399
Query: 466 GYAGRTCSLDVD---DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
G+ G C + D C C +G + L C C G++G +C D C G
Sbjct: 1400 GHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC-DREISCRGERI 1458
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNC 548
+ AAC T + C G G C
Sbjct: 1459 RDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 62.5 bits (145), Expect = 7e-09
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ-----CQPYP 247
C G++G+NCE V C++ + C D + C C P + GELC + Q
Sbjct: 986 CADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLN 1045
Query: 248 GCKH-GYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H C + C C + G CD D + C ++ C++G C + A + Y C C
Sbjct: 1046 PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNK-CKNGAHCTD-AVNGYTCICP 1103
Query: 305 EGFSGVDCERVDNPCAPQ--PCAHGTC 329
EG+SG+ CE P+ PC + C
Sbjct: 1104 EGYSGLFCEFSPPMVLPRTSPCDNFDC 1130
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/171 (24%), Positives = 63/171 (36%), Gaps = 20/171 (11%)
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C +PC N C + D+Y C C G+ G++C V + C C
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDC-----------DVPIHA---CISNPCK 967
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTC +EG + TC+ + C C
Sbjct: 968 HGGTCHLKEGE-EDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLC 1024
Query: 636 REGRTGALCELSLDLCGS--SPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
TG LCE LD C +PC++ +C+ + C+C G+ GE C +
Sbjct: 1025 PPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1075
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELSLDL---CGSSPCRNGGRCVGGSGWWMCECVA 675
GTCLP +A ++C C EG G LC+ DL C + C++G + G G CEC +
Sbjct: 1383 GTCLPINAF--SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSS 1440
Query: 676 GWTGETCAVRVS 687
G+TG++C +S
Sbjct: 1441 GYTGDSCDREIS 1452
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 24/139 (17%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH--GRC---DRPGDCDCRPGWRGELCS----QCQPY 246
C P + G+ CE+ + C + +P +C + CDC PG+ GE C CQ
Sbjct: 1024 CPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDN 1083
Query: 247 PGCKHG-YCNGS--SWDCTCDTNWGGILCDQD-------LNYCGTHEPCQHGGTCENTAP 296
CK+G +C + + C C + G+ C+ + C + CQ+G C
Sbjct: 1084 K-CKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCI-VRI 1140
Query: 297 DQYFCRCAEGFSGVDCERV 315
++ C+C G+ G CE++
Sbjct: 1141 NEPICQCLPGYQGEKCEKL 1159
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 618 AGGTCLPSALPPGWACGCREGRTGALC-ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
A GTC PS+ G+ C C+EG G LC + + D C + C +G + + C+C+ G
Sbjct: 1342 AHGTCQPSS-QAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEG 1400
Query: 677 WTGETC 682
G C
Sbjct: 1401 HGGVLC 1406
Score = 40.7 bits (91), Expect = 0.025
Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 32/163 (19%)
Query: 178 CRPRDDKF-GHYSCTPDGDK----HCLPGWQGDNCEK----PVCKEGCHPTHGRCDRPG- 227
C P K H +C P C GW G C++ P C HG C
Sbjct: 1333 CEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC--VHGTCLPINA 1390
Query: 228 ---DCDCRPGWRGELCSQ-------CQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQ 274
C C G G LC + CQ CKHG C S C C + + G CD+
Sbjct: 1391 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIK-CKHGKCRLSGLGQPYCECSSGYTGDSCDR 1449
Query: 275 DLNYCGT-----HEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+++ G ++ Q C+ T C G +G C
Sbjct: 1450 EISCRGERIRDYYQKQQGYAACQTTKKVSRL-ECRGGCAGGQC 1491
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 1/75 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSPCGNGAACYTAQSDY 535
+ C + C +G + C C G+ G C+ D C G+ C +G Y
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1393
Query: 536 YCHCAPGWTGKNCTQ 550
C C G G C +
Sbjct: 1394 SCKCLEGHGGVLCDE 1408
Score = 33.5 bits (73), Expect = 3.8
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C C +G ++Q+ + C C GW G C QR
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQR 1370
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 651 CGSSPCRNGGRCVGGS-GWWMCECVAGWTGETCAVRV 686
C S+PC+N G C ++ C C G+ G+ C V +
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPI 958
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 170 bits (414), Expect = 2e-41
Identities = 88/237 (37%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE N C+ PC + GTC + G FTC+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1048
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1049 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 929 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDA 987
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 988 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1099
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1100 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Query: 546 KNC 548
C
Sbjct: 1160 PEC 1162
Score = 132 bits (318), Expect = 8e-30
Identities = 66/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE +++ C+ G C +G TC + F C+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1098
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1099 MDEVNSY 1105
Score = 123 bits (296), Expect = 4e-27
Identities = 73/247 (29%), Positives = 102/247 (41%), Gaps = 24/247 (9%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
C C P G C+ + C C + + G C+ LN C + PC++GGTC
Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSS-GPCENGGTCHAQEG 984
Query: 297 DQ--YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
+ + C C GF G C + C CA+G + G +TC C + G
Sbjct: 985 EDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDG-VGNYTCQCPLQYEGKACEQL 1043
Query: 355 XXXXAS--GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNA 412
+ PC H A C DG CEC G+ G C+E+ D+C C N
Sbjct: 1044 VDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHR--------CQNG 1095
Query: 413 AACNNTAGGYSCACLAGWTGRDCE------TNVDDCTG-QCLHGATCIDLVDDFHCACAA 465
A C + YSC C G++G+ CE C G +C +GA C+D + C C
Sbjct: 1096 AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLP 1155
Query: 466 GYAGRTC 472
G+ G C
Sbjct: 1156 GFGGPEC 1162
Score = 105 bits (252), Expect = 8e-22
Identities = 63/219 (28%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELC----SQCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C + C P G C+ + C+C T + G C + + C
Sbjct: 950 CACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1009
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1010 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1066
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1127 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 102 bits (244), Expect = 7e-21
Identities = 70/260 (26%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + ++ C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQ 982
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1037
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1038 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1089 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 101 bits (243), Expect = 1e-20
Identities = 60/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE + C+ PC NG C+ + +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGED 986
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 987 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1032
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Score = 90.6 bits (215), Expect = 2e-17
Identities = 60/214 (28%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 198 CLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQ 244
C G++G +CE + C+ G CH G D P C C G+ G C C
Sbjct: 952 CPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCV 1010
Query: 245 PYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFC 301
+ G C +G ++ C C + G C+Q ++ C PCQH C T PD C
Sbjct: 1011 DHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRC 1069
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-S 360
C G++G +C + C C +G ++C C G+ G A
Sbjct: 1070 ECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPK 1128
Query: 361 GP-----CLHGASCRDHLDGFTCECADGWTGPAC 389
P C +GA+C D + C+C G+ GP C
Sbjct: 1129 SPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Score = 72.5 bits (170), Expect = 7e-12
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 11/116 (9%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1339 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1395
Query: 296 PDQYFCRCAEGFSGVDCER---VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C +G+SG C + + PC C HG C +G T+G C CD G+ G
Sbjct: 1396 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASG-TKGAHCVCDPGFSG 1450
Score = 69.7 bits (163), Expect = 5e-11
Identities = 55/190 (28%), Positives = 77/190 (40%), Gaps = 25/190 (13%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1405
Query: 466 GYAGRTCSLD---VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
GY+G C+ + C C +G C+C GFSG CE + + C G P
Sbjct: 1406 GYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE-CRGDPV 1464
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNCTQ--RAARDRKT--CS------VLVEE 565
+ A C T + + C G+ C Q R R + T CS VE+
Sbjct: 1465 RDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEK 1524
Query: 566 SERCAEGMCA 575
+C +CA
Sbjct: 1525 PTKCGCALCA 1534
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/126 (31%), Positives = 50/126 (39%), Gaps = 14/126 (11%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1398
Query: 422 YSCACLAGWTGRDCE---TNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
YSC C G++G C + C G QCLHG HC C G++G C +
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-S 1457
Query: 478 DCAPRP 483
+C P
Sbjct: 1458 ECRGDP 1463
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 28/173 (16%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1355 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1413
Query: 242 Q----CQPYPG--CKHGYCNGSSW---DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
Q +P G C HG+C S C CD + G LC+Q+ G +P +
Sbjct: 1414 QAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRG--DPVR---DFH 1468
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
C+ S V+C C Q C G L R FT C G
Sbjct: 1469 QVQRGYAICQTTRPLSWVECR---GSCPGQGCCQG---LRLKRRKFTFECSDG 1515
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1022 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1076 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1132
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 499 CICPVGFSGTNCEDDRDH-CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C C G+ G +C+ D C G C +G Y C C G++G C Q A +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGAL-AE 1420
Query: 558 TCSVLVEESERCAEGMCANGGT 579
C L +C G C GT
Sbjct: 1421 PCRGL-----QCLHGHCQASGT 1437
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELS---LDLCGSSPCRNGGRCVGGSGWWMCECVA 675
G C+P AL ++C C++G +GALC + + C C +G G+ C C
Sbjct: 1389 GQCVPLDAL--SYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDP 1446
Query: 676 GWTGETC 682
G++GE C
Sbjct: 1447 GFSGELC 1453
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1350 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1407
Query: 678 TGETC 682
+G C
Sbjct: 1408 SGALC 1412
Score = 35.9 bits (79), Expect = 0.72
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 649 DLCGSSPCRNGGRCVGGS-GWWMCECVAGWTGETCAVRVS 687
DLC SSPC+N G C + C C +G+ G C V ++
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLN 966
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 168 bits (409), Expect = 7e-41
Identities = 87/237 (36%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE + C+ PC + GTC + G FTC+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1048
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1049 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 929 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 988 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1099
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1100 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Query: 546 KNC 548
C
Sbjct: 1160 PEC 1162
Score = 134 bits (323), Expect = 2e-30
Identities = 67/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE ++D C+ G C +G TC + F C+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1098
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1099 MDEVNSY 1105
Score = 105 bits (251), Expect = 1e-21
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C C P G C+ + C+C T + G C + + C
Sbjct: 950 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1009
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1010 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1066
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1127 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 104 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + +D C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1037
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1038 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1089 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 103 bits (248), Expect = 2e-21
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE D C+ PC NG C+ + +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 987 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1032
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC-NG- 256
D+C C+ G CH G D P C C G+ G C C + G C +G
Sbjct: 966 DSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV 1024
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
++ C C + G C+Q ++ C PCQH C T PD C C G++G +C
Sbjct: 1025 GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRCECMPGYAGDNCSEN 1083
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-SGP-----CLHGASC 369
+ C C +G ++C C G+ G A P C +GA+C
Sbjct: 1084 QDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 370 RDHLDGFTCECADGWTGPAC 389
D + C+C G+ GP C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 72.5 bits (170), Expect = 7e-12
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 11/116 (9%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1339 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1395
Query: 296 PDQYFCRCAEGFSGVDCER---VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C +G+SG C + + PC C HG C +G T+G C CD G+ G
Sbjct: 1396 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASG-TKGAHCVCDPGFSG 1450
Score = 69.7 bits (163), Expect = 5e-11
Identities = 55/190 (28%), Positives = 77/190 (40%), Gaps = 25/190 (13%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1405
Query: 466 GYAGRTCSLD---VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
GY+G C+ + C C +G C+C GFSG CE + + C G P
Sbjct: 1406 GYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE-CRGDPV 1464
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNCTQ--RAARDRKT--CS------VLVEE 565
+ A C T + + C G+ C Q R R + T CS VE+
Sbjct: 1465 RDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEK 1524
Query: 566 SERCAEGMCA 575
+C +CA
Sbjct: 1525 PTKCGCALCA 1534
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/126 (31%), Positives = 50/126 (39%), Gaps = 14/126 (11%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1398
Query: 422 YSCACLAGWTGRDCE---TNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
YSC C G++G C + C G QCLHG HC C G++G C +
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-S 1457
Query: 478 DCAPRP 483
+C P
Sbjct: 1458 ECRGDP 1463
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 28/173 (16%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1355 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1413
Query: 242 Q----CQPYPG--CKHGYCNGSSW---DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
Q +P G C HG+C S C CD + G LC+Q+ G +P +
Sbjct: 1414 QAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRG--DPVR---DFH 1468
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
C+ S V+C C Q C G L R FT C G
Sbjct: 1469 QVQRGYAICQTTRPLSWVECR---GSCPGQGCCQG---LRLKRRKFTFECSDG 1515
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1022 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1076 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1132
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 499 CICPVGFSGTNCEDDRDH-CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C C G+ G +C+ D C G C +G Y C C G++G C Q A +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGAL-AE 1420
Query: 558 TCSVLVEESERCAEGMCANGGT 579
C L +C G C GT
Sbjct: 1421 PCRGL-----QCLHGHCQASGT 1437
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELS---LDLCGSSPCRNGGRCVGGSGWWMCECVA 675
G C+P AL ++C C++G +GALC + + C C +G G+ C C
Sbjct: 1389 GQCVPLDAL--SYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDP 1446
Query: 676 GWTGETC 682
G++GE C
Sbjct: 1447 GFSGELC 1453
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1350 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1407
Query: 678 TGETC 682
+G C
Sbjct: 1408 SGALC 1412
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 168 bits (409), Expect = 7e-41
Identities = 87/237 (36%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE + C+ PC + GTC + G FTC+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1048
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1049 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 929 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 988 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1099
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1100 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Query: 546 KNC 548
C
Sbjct: 1160 PEC 1162
Score = 134 bits (323), Expect = 2e-30
Identities = 67/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE ++D C+ G C +G TC + F C+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1098
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1099 MDEVNSY 1105
Score = 105 bits (251), Expect = 1e-21
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C C P G C+ + C+C T + G C + + C
Sbjct: 950 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1009
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1010 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1066
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1127 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 104 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + +D C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1037
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1038 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1089 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 103 bits (248), Expect = 2e-21
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE D C+ PC NG C+ + +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 987 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1032
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC-NG- 256
D+C C+ G CH G D P C C G+ G C C + G C +G
Sbjct: 966 DSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV 1024
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
++ C C + G C+Q ++ C PCQH C T PD C C G++G +C
Sbjct: 1025 GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRCECMPGYAGDNCSEN 1083
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-SGP-----CLHGASC 369
+ C C +G ++C C G+ G A P C +GA+C
Sbjct: 1084 QDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 370 RDHLDGFTCECADGWTGPAC 389
D + C+C G+ GP C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1022 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1076 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1132
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1405
Query: 466 GYAGRTCS 473
GY+G C+
Sbjct: 1406 GYSGALCN 1413
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1339 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1395
Query: 296 PDQYFCRCAEGFSGVDCER 314
Y C+C +G+SG C +
Sbjct: 1396 ALSYSCQCQDGYSGALCNQ 1414
Score = 46.8 bits (106), Expect = 4e-04
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C HG C+ A C C G+ G+ C++ D PC C HG C + ++C C
Sbjct: 1347 CLHG-ICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC-VPLDALSYSCQCQ 1404
Query: 344 RGWGG 348
G+ G
Sbjct: 1405 DGYSG 1409
Score = 44.0 bits (99), Expect = 0.003
Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 209 KPVCKEGCHPT------HGRCD---RPGD-CDCRPGWRGELCSQCQPYP----GCKHGYC 254
KP GC P HG C PG C C GW G C Q P C HG C
Sbjct: 1332 KPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC 1391
Query: 255 ---NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+ S+ C C + G LC+Q + GT
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCNQSPSAGGT 1421
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 10/114 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD-CAPRPCTNGGECVDL-LNAYRCICPV 503
CLHG + C C AG+ G C D C C +G +CV L +Y C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQD 1405
Query: 504 GFSGTNCEDDRD---HCAGSPCGNGAACYTAQSDYYCHCAPGWT-GKNCTQRAA 553
G+SG C +G+ + A +A+ CH GW+ G RAA
Sbjct: 1406 GYSGALCNQSPSAGGTLSGTFTRSRGAMPSARPRAPCH---GWSAGARAQARAA 1456
Score = 41.5 bits (93), Expect = 0.014
Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1398
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHG 449
YSC C G++G C N G L G
Sbjct: 1399 YSCQCQDGYSGALC--NQSPSAGGTLSG 1424
Score = 39.5 bits (88), Expect = 0.058
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1355 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1413
Query: 242 QCQPYPGCKHG 252
Q G G
Sbjct: 1414 QSPSAGGTLSG 1424
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1350 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1407
Query: 678 TGETC 682
+G C
Sbjct: 1408 SGALC 1412
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 168 bits (409), Expect = 7e-41
Identities = 87/237 (36%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE + C+ PC + GTC + G FTC+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1048
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1049 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 929 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 988 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1099
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1100 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Query: 546 KNC 548
C
Sbjct: 1160 PEC 1162
Score = 134 bits (323), Expect = 2e-30
Identities = 67/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE ++D C+ G C +G TC + F C+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1098
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1099 MDEVNSY 1105
Score = 105 bits (251), Expect = 1e-21
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C C P G C+ + C+C T + G C + + C
Sbjct: 950 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1009
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1010 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1066
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1127 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 104 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + +D C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1037
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1038 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1089 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 103 bits (248), Expect = 2e-21
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE D C+ PC NG C+ + +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 987 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1032
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC-NG- 256
D+C C+ G CH G D P C C G+ G C C + G C +G
Sbjct: 966 DSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV 1024
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
++ C C + G C+Q ++ C PCQH C T PD C C G++G +C
Sbjct: 1025 GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRCECMPGYAGDNCSEN 1083
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-SGP-----CLHGASC 369
+ C C +G ++C C G+ G A P C +GA+C
Sbjct: 1084 QDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 370 RDHLDGFTCECADGWTGPAC 389
D + C+C G+ GP C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1022 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1076 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1132
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1405
Query: 466 GYAGRTCS 473
GY+G C+
Sbjct: 1406 GYSGALCN 1413
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1339 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1395
Query: 296 PDQYFCRCAEGFSGVDCER 314
Y C+C +G+SG C +
Sbjct: 1396 ALSYSCQCQDGYSGALCNQ 1414
Score = 46.8 bits (106), Expect = 4e-04
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C HG C+ A C C G+ G+ C++ D PC C HG C + ++C C
Sbjct: 1347 CLHG-ICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC-VPLDALSYSCQCQ 1404
Query: 344 RGWGG 348
G+ G
Sbjct: 1405 DGYSG 1409
Score = 44.0 bits (99), Expect = 0.003
Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 209 KPVCKEGCHPT------HGRCD---RPGD-CDCRPGWRGELCSQCQPYP----GCKHGYC 254
KP GC P HG C PG C C GW G C Q P C HG C
Sbjct: 1332 KPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC 1391
Query: 255 ---NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+ S+ C C + G LC+Q + GT
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCNQSPSAGGT 1421
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 10/114 (8%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD-CAPRPCTNGGECVDL-LNAYRCICPV 503
CLHG + C C AG+ G C D C C +G +CV L +Y C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQD 1405
Query: 504 GFSGTNCEDDRD---HCAGSPCGNGAACYTAQSDYYCHCAPGWT-GKNCTQRAA 553
G+SG C +G+ + A +A+ CH GW+ G RAA
Sbjct: 1406 GYSGALCNQSPSAGGTLSGTFTRSRGAMPSARPRAPCH---GWSAGARAQARAA 1456
Score = 41.5 bits (93), Expect = 0.014
Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1398
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHG 449
YSC C G++G C N G L G
Sbjct: 1399 YSCQCQDGYSGALC--NQSPSAGGTLSG 1424
Score = 39.5 bits (88), Expect = 0.058
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1355 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1413
Query: 242 QCQPYPGCKHG 252
Q G G
Sbjct: 1414 QSPSAGGTLSG 1424
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1350 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1407
Query: 678 TGETC 682
+G C
Sbjct: 1408 SGALC 1412
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 168 bits (409), Expect = 7e-41
Identities = 87/237 (36%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE + C+ PC + GTC + G FTC+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1048
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1049 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 929 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 988 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1099
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1100 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Query: 546 KNC 548
C
Sbjct: 1160 PEC 1162
Score = 134 bits (323), Expect = 2e-30
Identities = 67/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE ++D C+ G C +G TC + F C+
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 992
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1098
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1099 MDEVNSY 1105
Score = 105 bits (251), Expect = 1e-21
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C C P G C+ + C+C T + G C + + C
Sbjct: 950 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1009
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1010 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1066
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1127 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 104 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + +D C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1037
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1038 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1089 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 103 bits (248), Expect = 2e-21
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE D C+ PC NG C+ + +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 987 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1032
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC-NG- 256
D+C C+ G CH G D P C C G+ G C C + G C +G
Sbjct: 966 DSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV 1024
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
++ C C + G C+Q ++ C PCQH C T PD C C G++G +C
Sbjct: 1025 GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRCECMPGYAGDNCSEN 1083
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-SGP-----CLHGASC 369
+ C C +G ++C C G+ G A P C +GA+C
Sbjct: 1084 QDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 370 RDHLDGFTCECADGWTGPAC 389
D + C+C G+ GP C
Sbjct: 1143 VDQGNRPVCQCLPGFGGPEC 1162
Score = 72.5 bits (170), Expect = 7e-12
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 11/116 (9%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1339 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1395
Query: 296 PDQYFCRCAEGFSGVDCER---VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C +G+SG C + + PC C HG C +G T+G C CD G+ G
Sbjct: 1396 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASG-TKGAHCVCDPGFSG 1450
Score = 69.7 bits (163), Expect = 5e-11
Identities = 55/190 (28%), Positives = 77/190 (40%), Gaps = 25/190 (13%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1405
Query: 466 GYAGRTCSLD---VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
GY+G C+ + C C +G C+C GFSG CE + + C G P
Sbjct: 1406 GYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE-CRGDPV 1464
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNCTQ--RAARDRKT--CS------VLVEE 565
+ A C T + + C G+ C Q R R + T CS VE+
Sbjct: 1465 RDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEK 1524
Query: 566 SERCAEGMCA 575
+C +CA
Sbjct: 1525 PTKCGCALCA 1534
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/126 (31%), Positives = 50/126 (39%), Gaps = 14/126 (11%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1398
Query: 422 YSCACLAGWTGRDCE---TNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
YSC C G++G C + C G QCLHG HC C G++G C +
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-S 1457
Query: 478 DCAPRP 483
+C P
Sbjct: 1458 ECRGDP 1463
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 28/173 (16%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1355 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1413
Query: 242 Q----CQPYPG--CKHGYCNGSSW---DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
Q +P G C HG+C S C CD + G LC+Q+ G +P +
Sbjct: 1414 QAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRG--DPVR---DFH 1468
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
C+ S V+C C Q C G L R FT C G
Sbjct: 1469 QVQRGYAICQTTRPLSWVECR---GSCPGQGCCQG---LRLKRRKFTFECSDG 1515
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1022 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1076 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1132
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 499 CICPVGFSGTNCEDDRDH-CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C C G+ G +C+ D C G C +G Y C C G++G C Q A +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGAL-AE 1420
Query: 558 TCSVLVEESERCAEGMCANGGT 579
C L +C G C GT
Sbjct: 1421 PCRGL-----QCLHGHCQASGT 1437
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELS---LDLCGSSPCRNGGRCVGGSGWWMCECVA 675
G C+P AL ++C C++G +GALC + + C C +G G+ C C
Sbjct: 1389 GQCVPLDAL--SYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDP 1446
Query: 676 GWTGETC 682
G++GE C
Sbjct: 1447 GFSGELC 1453
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1350 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1407
Query: 678 TGETC 682
+G C
Sbjct: 1408 SGALC 1412
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 168 bits (409), Expect = 7e-41
Identities = 87/237 (36%), Positives = 115/237 (48%), Gaps = 15/237 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCT 341
PCQ+ GTC N + Y C C G+ G DCE + C+ PC + GTC + G FTC+
Sbjct: 1017 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 1076
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C +G C D + +TC+C + G AC + VD CS
Sbjct: 1077 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS---- 1132
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L PC + A C T G C C+ G+ G +C N DDC +C +GA C+D V+ +
Sbjct: 1133 --PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1190
Query: 461 CACAAGYAGRTCSLDVDDCAPR------PCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C CA GY+G+ C + AP+ C NG CVD N C C GF G CE
Sbjct: 1191 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1247
Score = 162 bits (394), Expect = 5e-39
Identities = 83/243 (34%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDG 375
C PC + GTC + C C G+ G +SGPC +G +C ++ D
Sbjct: 1013 CLSSPCQNQGTCH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 1071
Query: 376 -FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
FTC C G+ GP C + D+C + C N C + G Y+C C + G+
Sbjct: 1072 PFTCSCPTGFEGPTCGVNTDDCVDHA--------CANGGVCVDGVGNYTCQCPLQYEGKA 1123
Query: 435 CETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
CE VD C+ C H A C+ D C C GYAG CS + DDC C NG +C+
Sbjct: 1124 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM 1183
Query: 492 DLLNAYRCICPVGFSGTNCE------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTG 545
D +N+Y C+C G+SG CE + C G+ C NGA C + C C PG+ G
Sbjct: 1184 DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1243
Query: 546 KNC 548
C
Sbjct: 1244 PEC 1246
Score = 134 bits (323), Expect = 2e-30
Identities = 67/187 (35%), Positives = 91/187 (48%), Gaps = 21/187 (11%)
Query: 408 PCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDD---FHCA 462
PC N C+N Y CAC +G+ GRDCE ++D C+ G C +G TC + F C+
Sbjct: 1017 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCS 1076
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G TC ++ DDC C NGG CVD + Y C CP+ + G CE D C+ +
Sbjct: 1077 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1136
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC + A C C C PG+ G NC+ E + C + C NG C
Sbjct: 1137 PCQHEAQCVGTPDGPRCECMPGYAGDNCS--------------ENQDDCRDHRCQNGAQC 1182
Query: 581 VREEGSW 587
+ E S+
Sbjct: 1183 MDEVNSY 1189
Score = 105 bits (251), Expect = 1e-21
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSSWD-----CTCDTNWGGILCDQDLNYC 279
C C G++G C C P G C+ + C+C T + G C + + C
Sbjct: 1034 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC 1093
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP--QPCAHGTCSLAGTTRG 337
H C +GG C + Y C+C + G CE++ + C+P PC H GT G
Sbjct: 1094 VDH-ACANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQH-EAQCVGTPDG 1150
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
C C G+ G C +GA C D ++ ++C CA+G++G C +
Sbjct: 1151 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1210
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
+S EG C N A C + C CL G+ G +CE
Sbjct: 1211 PKSPCEGT--ECQNGANCVDQGNRPVCQCLPGFGGPECE 1247
Score = 104 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 100/260 (38%), Gaps = 33/260 (12%)
Query: 436 ETNVDDC-TGQCLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ D C + C + TC D ++ + CAC +GY GR C + +D C+ PC NGG C
Sbjct: 1007 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 1066
Query: 494 LNA---YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+ C CP GF G C + D C C NG C +Y C C + G
Sbjct: 1067 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG----- 1121
Query: 551 RAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXX 608
K C LV+ C+ + C + CV R
Sbjct: 1122 ------KACEQLVD---LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1172
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDL------CGSSPCRNGGRC 662
Q G C+ ++C C EG +G LCE+ L C + C+NG C
Sbjct: 1173 DHRC----QNGAQCMDEV--NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1226
Query: 663 VGGSGWWMCECVAGWTGETC 682
V +C+C+ G+ G C
Sbjct: 1227 VDQGNRPVCQCLPGFGGPEC 1246
Score = 103 bits (248), Expect = 2e-21
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 477 DDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD- 534
D C PC N G C D L YRC CP G+ G +CE D C+ PC NG C+ + +
Sbjct: 1011 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 1070
Query: 535 --YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
+ C C G+ G TC V ++ C + CANGG CV G++
Sbjct: 1071 APFTCSCPTGFEGP-----------TCGVNTDD---CVDHACANGGVCVDGVGNYTCQCP 1116
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
+ +A C+ + P G C C G G C + D C
Sbjct: 1117 LQYEGKACEQLVDLCSPDLNPCQHEA--QCVGT--PDGPRCECMPGYAGDNCSENQDDCR 1172
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C+NG +C+ + C C G++G+ C +
Sbjct: 1173 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1204
Score = 92.3 bits (219), Expect = 8e-18
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC-NG- 256
D+C C+ G CH G D P C C G+ G C C + G C +G
Sbjct: 1050 DSCSSGPCENGGTCHAQEGE-DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV 1108
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
++ C C + G C+Q ++ C PCQH C T PD C C G++G +C
Sbjct: 1109 GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT-PDGPRCECMPGYAGDNCSEN 1167
Query: 316 DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA-SGP-----CLHGASC 369
+ C C +G ++C C G+ G A P C +GA+C
Sbjct: 1168 QDDCRDHRCQNG-AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1226
Query: 370 RDHLDGFTCECADGWTGPAC 389
D + C+C G+ GP C
Sbjct: 1227 VDQGNRPVCQCLPGFGGPEC 1246
Score = 72.5 bits (170), Expect = 7e-12
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 11/116 (9%)
Query: 240 CSQCQPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLN-YCGTHEPCQHGGTCENTA 295
C C+ C HG C ++ C C+ W G+ CDQ + C H+ C H G C
Sbjct: 1423 CEPCRKLY-CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK-CVH-GQCVPLD 1479
Query: 296 PDQYFCRCAEGFSGVDCER---VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
Y C+C +G+SG C + + PC C HG C +G T+G C CD G+ G
Sbjct: 1480 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASG-TKGAHCVCDPGFSG 1534
Score = 69.7 bits (163), Expect = 5e-11
Identities = 55/190 (28%), Positives = 77/190 (40%), Gaps = 25/190 (13%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDD-CTG-QCLHGATCIDL-VDDFHCACAA 465
C++ N G C C AGW G C+ D C G +C+HG C+ L + C C
Sbjct: 1431 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQD 1489
Query: 466 GYAGRTCSLD---VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
GY+G C+ + C C +G C+C GFSG CE + + C G P
Sbjct: 1490 GYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE-CRGDPV 1548
Query: 523 GN-------GAACYTAQSDYYCHCAPGWTGKNCTQ--RAARDRKT--CS------VLVEE 565
+ A C T + + C G+ C Q R R + T CS VE+
Sbjct: 1549 RDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEK 1608
Query: 566 SERCAEGMCA 575
+C +CA
Sbjct: 1609 PTKCGCALCA 1618
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/126 (31%), Positives = 50/126 (39%), Gaps = 14/126 (11%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGG 421
CLHG + G C C GW G C + D C G G CV A +
Sbjct: 1431 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH---GQCVPLDALS----- 1482
Query: 422 YSCACLAGWTGRDCE---TNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
YSC C G++G C + C G QCLHG HC C G++G C +
Sbjct: 1483 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-S 1541
Query: 478 DCAPRP 483
+C P
Sbjct: 1542 ECRGDP 1547
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 28/173 (16%)
Query: 189 SCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRC---DRPG-DCDCRPGWRGELCS 241
+ TP HC GW G +C++P CH HG+C D C C+ G+ G LC+
Sbjct: 1439 NATPGPMCHCEAGWVGLHCDQP-ADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN 1497
Query: 242 Q----CQPYPG--CKHGYCNGSSW---DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCE 292
Q +P G C HG+C S C CD + G LC+Q+ G +P +
Sbjct: 1498 QAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRG--DPVR---DFH 1552
Query: 293 NTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
C+ S V+C C Q C G L R FT C G
Sbjct: 1553 QVQRGYAICQTTRPLSWVECR---GSCPGQGCCQG---LRLKRRKFTFECSDG 1599
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 29/153 (18%)
Query: 183 DKFGHYSCTPDGDKHCLPGWQGDNCEKPV--CKEGCHPTH--GRCDRPGD---CDCRPGW 235
D G+Y+C C ++G CE+ V C +P +C D C+C PG+
Sbjct: 1106 DGVGNYTC------QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1159
Query: 236 RGELCSQCQPYPGCKHGYC-NG-------SSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
G+ CS+ Q C+ C NG +S+ C C + G LC+ + PC+
Sbjct: 1160 AGDNCSENQ--DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE- 1216
Query: 288 GGTCENTA-----PDQYFCRCAEGFSGVDCERV 315
G C+N A ++ C+C GF G +CE++
Sbjct: 1217 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1249
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 499 CICPVGFSGTNCEDDRDH-CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C C G+ G +C+ D C G C +G Y C C G++G C Q A +
Sbjct: 1446 CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGAL-AE 1504
Query: 558 TCSVLVEESERCAEGMCANGGT 579
C L +C G C GT
Sbjct: 1505 PCRGL-----QCLHGHCQASGT 1521
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
Query: 620 GTCLP-SALPPGWACGCREGRTGALCELS---LDLCGSSPCRNGGRCVGGSGWWMCECVA 675
G C+P AL ++C C++G +GALC + + C C +G G+ C C
Sbjct: 1473 GQCVPLDAL--SYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDP 1530
Query: 676 GWTGETC 682
G++GE C
Sbjct: 1531 GFSGELC 1537
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLD-LCGSSPCRNGGRCVGGSGW-WMCECVAGW 677
G C P+A P G C C G G C+ D C C + G+CV + C+C G+
Sbjct: 1434 GICQPNATP-GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDALSYSCQCQDGY 1491
Query: 678 TGETC 682
+G C
Sbjct: 1492 SGALC 1496
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 167 bits (406), Expect = 2e-40
Identities = 84/246 (34%), Positives = 105/246 (42%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
N C PC + GTC+ + C C + G PC HG +C H
Sbjct: 918 NACLSSPCKNNGTCT-QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSH 976
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF+C C G+ G C + D+C C N A C + Y C C +TG
Sbjct: 977 KDGFSCSCPLGFEGQRCEINPDDCEDND--------CENNATCVDGINNYVCICPPNYTG 1028
Query: 433 RDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
C+ +D C + C H A CI L F C C GY+G+ C D DDC C +G +
Sbjct: 1029 ELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQ 1088
Query: 490 CVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
CVD +N Y C CP GFSG CE C C NGA C Q + C C PG
Sbjct: 1089 CVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPG 1148
Query: 543 WTGKNC 548
+ G C
Sbjct: 1149 FAGPRC 1154
Score = 166 bits (403), Expect = 4e-40
Identities = 79/238 (33%), Positives = 114/238 (47%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTR-GFTCT 341
PC++ GTC + Y C C + G DC N C PC H GTC L+ + + GF+C+
Sbjct: 924 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 983
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + A+C D ++ + C C +TG C E +D C
Sbjct: 984 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPE-- 1041
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L C + A C G+SC C+ G++G+ CET+ DDC +C HGA C+D ++ +
Sbjct: 1042 ----LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
Query: 461 CACAAGYAGRTCS-------LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C G++G C L C C NG +C+ + C CP GF+G CE
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 92.7 bits (220), Expect = 6e-18
Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Query: 446 CLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV---DLLNAYRCIC 501
C + TC D V+ + CAC Y G+ C++ ++ C PC +GG C + + C C
Sbjct: 925 CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSC 984
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
P+GF G CE + D C + C N A C ++Y C C P +TG+ C +
Sbjct: 985 PLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDE 1033
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 22/208 (10%)
Query: 479 CAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--- 534
C PC N G C D + YRC CP + G +C + C +PC +G C+ + S
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+ C C G+ G+ C + C + C N TCV ++
Sbjct: 980 FSCSCPLGFEGQRCEINP--------------DDCEDNDCENNATCVDGINNYVCICPPN 1025
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
D +A C+P L G++C C G +G LCE D C +
Sbjct: 1026 YTGELCDEVIDHCVPELNLCQHEA--KCIP--LDKGFSCECVPGYSGKLCETDNDDCVAH 1081
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
CR+G +CV + C C G++G C
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFC 1109
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/215 (27%), Positives = 89/215 (41%), Gaps = 26/215 (12%)
Query: 198 CLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQ 244
C ++G +C P+ C+ G CH + D C C G+ G+ C C+
Sbjct: 943 CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG-FSCSCPLGFEGQRCEINPDDCE 1001
Query: 245 PYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFC 301
+ C +G +++ C C N+ G LCD+ +++C CQH C + C
Sbjct: 1002 DNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC-IPLDKGFSC 1060
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXX--XXXXXA 359
C G+SG CE ++ C C HG T G+TCTC +G+ G
Sbjct: 1061 ECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQ 1119
Query: 360 SGP-----CLHGASCRDHLDGFTCECADGWTGPAC 389
+ P C +GA C TC C G+ GP C
Sbjct: 1120 TSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/126 (38%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 210 PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ--CQPYPG--CKHGYC--NGSSW 259
P CK HG C C+CRPGW G LC Q P G C HG C G+S+
Sbjct: 1330 PGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSY 1389
Query: 260 DCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C C +GG LCD N C + C H G C + + +C C GFSG C++ +
Sbjct: 1390 MCKCAEGYGGDLCDNKNDSANACSAFK-CHH-GQCHISDQGEPYCLCQPGFSGEHCQQ-E 1446
Query: 317 NPCAPQ 322
NPC Q
Sbjct: 1447 NPCLGQ 1452
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV-DDCAPRPCTNGGECVDLLNAYRCI 500
CT C HG D C C G+ G C + D C C +G +CV +Y C
Sbjct: 1335 CT-VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCK 1392
Query: 501 CPVGFSGTNCEDDRDH---CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C G+ G C++ D C+ C +G + Q + YC C PG++G++C Q
Sbjct: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
Score = 65.7 bits (153), Expect = 8e-10
Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 424 CACLAGWTGRDCETNV-DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD---C 479
C C GWTG C+ D C G H C+ + C CA GY G C D C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-------GNGAACYTAQ 532
+ C +G + C+C GFSG +C+ + + C G A+C TA
Sbjct: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQVVREVIRRQKGYASCATAS 1471
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRK---TC---SVLVEESERCAEGMC 574
C G + C ++ RK C S VEE ER E C
Sbjct: 1472 KVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGC 1519
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRG 337
C + C+HG C + D C C G++G C++ +PC C HG C GT+
Sbjct: 1332 CKSCTVCKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS-- 1388
Query: 338 FTCTCDRGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFT-CECADGWTGPACAEDV 393
+ C C G+GG ++ C HG C G C C G++G C ++
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE- 1446
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE---TNVDDCTGQCLHGA 450
+ C G+ + E + A+C + C G + C+ + QC G+
Sbjct: 1447 NPCLGQVVRE-VIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGS 1505
Query: 451 TCIDLVD-DFHCACAA 465
+ ++ V+ C C A
Sbjct: 1506 SFVEEVERHLECGCLA 1521
Score = 62.5 bits (145), Expect = 7e-09
Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG D CEC GWTGP C ++ D C G G C T
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG---------KCVATGTS 1388
Query: 422 YSCACLAGWTGRDCETNVDD---CTG-QCLHGATCIDLVDDFHCACAAGYAGRTC 472
Y C C G+ G C+ D C+ +C HG I + +C C G++G C
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 28/141 (19%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRC---------DRPGDCDCRPGWRGELCS----QCQ 244
C P + G+ C++ + + C P C D+ C+C PG+ G+LC C
Sbjct: 1022 CPPNYTGELCDEVI--DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV 1079
Query: 245 PYPGCKHG-YCNGS--SWDCTCDTNWGGILCDQ-------DLNYCGTHEPCQHGGTCENT 294
+ C+HG C + + CTC + G C+ + C +E CQ+G C
Sbjct: 1080 AHK-CRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYE-CQNGAQCI-V 1136
Query: 295 APDQYFCRCAEGFSGVDCERV 315
+ CRC GF+G CE++
Sbjct: 1137 VQQEPTCRCPPGFAGPRCEKL 1157
Score = 48.4 bits (110), Expect = 1e-04
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 198 CLPGWQGDNCEK----PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC-------SQC 243
C PGW G C++ P CH HG+C G C C G+ G+LC + C
Sbjct: 1355 CRPGWTGPLCDQEARDPCLGHRCH--HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412
Query: 244 QPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
+ C HG C+ S C C + G C Q+ PC E + +
Sbjct: 1413 SAFK-CHHGQCHISDQGEPYCLCQPGFSGEHCQQE-------NPCLGQVVREVIRRQKGY 1464
Query: 301 CRCAEGFSGVDCERVDNPCAPQPC 324
CA S V C PQ C
Sbjct: 1465 ASCATA-SKVPIMECRGGCGPQCC 1487
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 633 CGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C CR G TG LC+ D C C +G +CV +MC+C G+ G+ C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC 1402
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC---VGGSGWWMCECVAG 676
GTC + + C C G C + ++ C +PC++GG C + C C G
Sbjct: 929 GTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLG 987
Query: 677 WTGETCAV 684
+ G+ C +
Sbjct: 988 FEGQRCEI 995
Score = 37.5 bits (83), Expect = 0.24
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 7/60 (11%)
Query: 630 GWACGCREGRTGALCE-------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G+ C C +G +G CE L C C+NG +C+ C C G+ G C
Sbjct: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCEL---SLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
G C+ A + C C EG G LC+ S + C + C +G + G C C G
Sbjct: 1380 GKCV--ATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPG 1437
Query: 677 WTGETC 682
++GE C
Sbjct: 1438 FSGEHC 1443
Score = 36.3 bits (80), Expect = 0.54
Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 8/58 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C +G + C C PGWTG C Q A R C RC G C GT
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEA---RDPCL-----GHRCHHGKCVATGT 1387
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 167 bits (406), Expect = 2e-40
Identities = 84/246 (34%), Positives = 105/246 (42%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
N C PC + GTC+ + C C + G PC HG +C H
Sbjct: 918 NACLSSPCKNNGTCT-QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSH 976
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF+C C G+ G C + D+C C N A C + Y C C +TG
Sbjct: 977 KDGFSCSCPLGFEGQRCEINPDDCEDND--------CENNATCVDGINNYVCICPPNYTG 1028
Query: 433 RDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
C+ +D C + C H A CI L F C C GY+G+ C D DDC C +G +
Sbjct: 1029 ELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQ 1088
Query: 490 CVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
CVD +N Y C CP GFSG CE C C NGA C Q + C C PG
Sbjct: 1089 CVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPG 1148
Query: 543 WTGKNC 548
+ G C
Sbjct: 1149 FAGPRC 1154
Score = 166 bits (403), Expect = 4e-40
Identities = 79/238 (33%), Positives = 114/238 (47%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTR-GFTCT 341
PC++ GTC + Y C C + G DC N C PC H GTC L+ + + GF+C+
Sbjct: 924 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 983
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + A+C D ++ + C C +TG C E +D C
Sbjct: 984 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPE-- 1041
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L C + A C G+SC C+ G++G+ CET+ DDC +C HGA C+D ++ +
Sbjct: 1042 ----LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
Query: 461 CACAAGYAGRTCS-------LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C G++G C L C C NG +C+ + C CP GF+G CE
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 92.7 bits (220), Expect = 6e-18
Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Query: 446 CLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV---DLLNAYRCIC 501
C + TC D V+ + CAC Y G+ C++ ++ C PC +GG C + + C C
Sbjct: 925 CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSC 984
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
P+GF G CE + D C + C N A C ++Y C C P +TG+ C +
Sbjct: 985 PLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDE 1033
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 22/208 (10%)
Query: 479 CAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--- 534
C PC N G C D + YRC CP + G +C + C +PC +G C+ + S
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+ C C G+ G+ C + C + C N TCV ++
Sbjct: 980 FSCSCPLGFEGQRCEINP--------------DDCEDNDCENNATCVDGINNYVCICPPN 1025
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
D +A C+P L G++C C G +G LCE D C +
Sbjct: 1026 YTGELCDEVIDHCVPELNLCQHEA--KCIP--LDKGFSCECVPGYSGKLCETDNDDCVAH 1081
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
CR+G +CV + C C G++G C
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFC 1109
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/215 (27%), Positives = 89/215 (41%), Gaps = 26/215 (12%)
Query: 198 CLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQ 244
C ++G +C P+ C+ G CH + D C C G+ G+ C C+
Sbjct: 943 CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG-FSCSCPLGFEGQRCEINPDDCE 1001
Query: 245 PYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFC 301
+ C +G +++ C C N+ G LCD+ +++C CQH C + C
Sbjct: 1002 DNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC-IPLDKGFSC 1060
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXX--XXXXXA 359
C G+SG CE ++ C C HG T G+TCTC +G+ G
Sbjct: 1061 ECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQ 1119
Query: 360 SGP-----CLHGASCRDHLDGFTCECADGWTGPAC 389
+ P C +GA C TC C G+ GP C
Sbjct: 1120 TSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/126 (38%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 210 PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ--CQPYPG--CKHGYC--NGSSW 259
P CK HG C C+CRPGW G LC Q P G C HG C G+S+
Sbjct: 1330 PGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSY 1389
Query: 260 DCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C C +GG LCD N C + C H G C + + +C C GFSG C++ +
Sbjct: 1390 MCKCAEGYGGDLCDNKNDSANACSAFK-CHH-GQCHISDQGEPYCLCQPGFSGEHCQQ-E 1446
Query: 317 NPCAPQ 322
NPC Q
Sbjct: 1447 NPCLGQ 1452
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV-DDCAPRPCTNGGECVDLLNAYRCI 500
CT C HG D C C G+ G C + D C C +G +CV +Y C
Sbjct: 1335 CT-VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCK 1392
Query: 501 CPVGFSGTNCEDDRDH---CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C G+ G C++ D C+ C +G + Q + YC C PG++G++C Q
Sbjct: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
Score = 65.7 bits (153), Expect = 8e-10
Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 424 CACLAGWTGRDCETNV-DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD---C 479
C C GWTG C+ D C G H C+ + C CA GY G C D C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-------GNGAACYTAQ 532
+ C +G + C+C GFSG +C+ + + C G A+C TA
Sbjct: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQVVREVIRRQKGYASCATAS 1471
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRK---TC---SVLVEESERCAEGMC 574
C G + C ++ RK C S VEE ER E C
Sbjct: 1472 KVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGC 1519
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRG 337
C + C+HG C + D C C G++G C++ +PC C HG C GT+
Sbjct: 1332 CKSCTVCKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS-- 1388
Query: 338 FTCTCDRGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFT-CECADGWTGPACAEDV 393
+ C C G+GG ++ C HG C G C C G++G C ++
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE- 1446
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE---TNVDDCTGQCLHGA 450
+ C G+ + E + A+C + C G + C+ + QC G+
Sbjct: 1447 NPCLGQVVRE-VIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGS 1505
Query: 451 TCIDLVD-DFHCACAA 465
+ ++ V+ C C A
Sbjct: 1506 SFVEEVERHLECGCLA 1521
Score = 62.5 bits (145), Expect = 7e-09
Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG D CEC GWTGP C ++ D C G G C T
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG---------KCVATGTS 1388
Query: 422 YSCACLAGWTGRDCETNVDD---CTG-QCLHGATCIDLVDDFHCACAAGYAGRTC 472
Y C C G+ G C+ D C+ +C HG I + +C C G++G C
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 28/141 (19%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRC---------DRPGDCDCRPGWRGELCS----QCQ 244
C P + G+ C++ + + C P C D+ C+C PG+ G+LC C
Sbjct: 1022 CPPNYTGELCDEVI--DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV 1079
Query: 245 PYPGCKHG-YCNGS--SWDCTCDTNWGGILCDQ-------DLNYCGTHEPCQHGGTCENT 294
+ C+HG C + + CTC + G C+ + C +E CQ+G C
Sbjct: 1080 AHK-CRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYE-CQNGAQCI-V 1136
Query: 295 APDQYFCRCAEGFSGVDCERV 315
+ CRC GF+G CE++
Sbjct: 1137 VQQEPTCRCPPGFAGPRCEKL 1157
Score = 48.4 bits (110), Expect = 1e-04
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 198 CLPGWQGDNCEK----PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC-------SQC 243
C PGW G C++ P CH HG+C G C C G+ G+LC + C
Sbjct: 1355 CRPGWTGPLCDQEARDPCLGHRCH--HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412
Query: 244 QPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
+ C HG C+ S C C + G C Q+ PC E + +
Sbjct: 1413 SAFK-CHHGQCHISDQGEPYCLCQPGFSGEHCQQE-------NPCLGQVVREVIRRQKGY 1464
Query: 301 CRCAEGFSGVDCERVDNPCAPQPC 324
CA S V C PQ C
Sbjct: 1465 ASCATA-SKVPIMECRGGCGPQCC 1487
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 633 CGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C CR G TG LC+ D C C +G +CV +MC+C G+ G+ C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC 1402
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC---VGGSGWWMCECVAG 676
GTC + + C C G C + ++ C +PC++GG C + C C G
Sbjct: 929 GTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLG 987
Query: 677 WTGETCAV 684
+ G+ C +
Sbjct: 988 FEGQRCEI 995
Score = 37.5 bits (83), Expect = 0.24
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 7/60 (11%)
Query: 630 GWACGCREGRTGALCE-------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G+ C C +G +G CE L C C+NG +C+ C C G+ G C
Sbjct: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCEL---SLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
G C+ A + C C EG G LC+ S + C + C +G + G C C G
Sbjct: 1380 GKCV--ATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPG 1437
Query: 677 WTGETC 682
++GE C
Sbjct: 1438 FSGEHC 1443
Score = 36.3 bits (80), Expect = 0.54
Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 8/58 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C +G + C C PGWTG C Q A R C RC G C GT
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEA---RDPCL-----GHRCHHGKCVATGT 1387
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 167 bits (406), Expect = 2e-40
Identities = 84/246 (34%), Positives = 105/246 (42%), Gaps = 23/246 (9%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
N C PC + GTC+ + C C + G PC HG +C H
Sbjct: 954 NACLSSPCKNNGTCT-QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSH 1012
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF+C C G+ G C + D+C C N A C + Y C C +TG
Sbjct: 1013 KDGFSCSCPLGFEGQRCEINPDDCEDND--------CENNATCVDGINNYVCICPPNYTG 1064
Query: 433 RDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
C+ +D C + C H A CI L F C C GY+G+ C D DDC C +G +
Sbjct: 1065 ELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQ 1124
Query: 490 CVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
CVD +N Y C CP GFSG CE C C NGA C Q + C C PG
Sbjct: 1125 CVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPG 1184
Query: 543 WTGKNC 548
+ G C
Sbjct: 1185 FAGPRC 1190
Score = 166 bits (403), Expect = 4e-40
Identities = 79/238 (33%), Positives = 114/238 (47%), Gaps = 16/238 (6%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTR-GFTCT 341
PC++ GTC + Y C C + G DC N C PC H GTC L+ + + GF+C+
Sbjct: 960 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 1019
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + A+C D ++ + C C +TG C E +D C
Sbjct: 1020 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPE-- 1077
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L C + A C G+SC C+ G++G+ CET+ DDC +C HGA C+D ++ +
Sbjct: 1078 ----LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1133
Query: 461 CACAAGYAGRTCS-------LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C C G++G C L C C NG +C+ + C CP GF+G CE
Sbjct: 1134 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1191
Score = 92.7 bits (220), Expect = 6e-18
Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Query: 446 CLHGATCI-DLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV---DLLNAYRCIC 501
C + TC D V+ + CAC Y G+ C++ ++ C PC +GG C + + C C
Sbjct: 961 CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSC 1020
Query: 502 PVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
P+GF G CE + D C + C N A C ++Y C C P +TG+ C +
Sbjct: 1021 PLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDE 1069
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 22/208 (10%)
Query: 479 CAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--- 534
C PC N G C D + YRC CP + G +C + C +PC +G C+ + S
Sbjct: 956 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 1015
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+ C C G+ G+ C + C + C N TCV ++
Sbjct: 1016 FSCSCPLGFEGQRCEINP--------------DDCEDNDCENNATCVDGINNYVCICPPN 1061
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
D +A C+P L G++C C G +G LCE D C +
Sbjct: 1062 YTGELCDEVIDHCVPELNLCQHEA--KCIP--LDKGFSCECVPGYSGKLCETDNDDCVAH 1117
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
CR+G +CV + C C G++G C
Sbjct: 1118 KCRHGAQCVDTINGYTCTCPQGFSGPFC 1145
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/215 (27%), Positives = 89/215 (41%), Gaps = 26/215 (12%)
Query: 198 CLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQ 244
C ++G +C P+ C+ G CH + D C C G+ G+ C C+
Sbjct: 979 CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG-FSCSCPLGFEGQRCEINPDDCE 1037
Query: 245 PYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFC 301
+ C +G +++ C C N+ G LCD+ +++C CQH C + C
Sbjct: 1038 DNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC-IPLDKGFSC 1096
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXX--XXXXXA 359
C G+SG CE ++ C C HG T G+TCTC +G+ G
Sbjct: 1097 ECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQ 1155
Query: 360 SGP-----CLHGASCRDHLDGFTCECADGWTGPAC 389
+ P C +GA C TC C G+ GP C
Sbjct: 1156 TSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1190
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/126 (38%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 210 PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ--CQPYPG--CKHGYC--NGSSW 259
P CK HG C C+CRPGW G LC Q P G C HG C G+S+
Sbjct: 1366 PGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSY 1425
Query: 260 DCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C C +GG LCD N C + C H G C + + +C C GFSG C++ +
Sbjct: 1426 MCKCAEGYGGDLCDNKNDSANACSAFK-CHH-GQCHISDQGEPYCLCQPGFSGEHCQQ-E 1482
Query: 317 NPCAPQ 322
NPC Q
Sbjct: 1483 NPCLGQ 1488
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Query: 442 CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV-DDCAPRPCTNGGECVDLLNAYRCI 500
CT C HG D C C G+ G C + D C C +G +CV +Y C
Sbjct: 1371 CT-VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCK 1428
Query: 501 CPVGFSGTNCEDDRDH---CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C G+ G C++ D C+ C +G + Q + YC C PG++G++C Q
Sbjct: 1429 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1481
Score = 65.7 bits (153), Expect = 8e-10
Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 424 CACLAGWTGRDCETNV-DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD---C 479
C C GWTG C+ D C G H C+ + C CA GY G C D C
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1448
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-------GNGAACYTAQ 532
+ C +G + C+C GFSG +C+ + + C G A+C TA
Sbjct: 1449 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQVVREVIRRQKGYASCATAS 1507
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRK---TC---SVLVEESERCAEGMC 574
C G + C ++ RK C S VEE ER E C
Sbjct: 1508 KVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGC 1555
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRG 337
C + C+HG C + D C C G++G C++ +PC C HG C GT+
Sbjct: 1368 CKSCTVCKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS-- 1424
Query: 338 FTCTCDRGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFT-CECADGWTGPACAEDV 393
+ C C G+GG ++ C HG C G C C G++G C ++
Sbjct: 1425 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE- 1482
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE---TNVDDCTGQCLHGA 450
+ C G+ + E + A+C + C G + C+ + QC G+
Sbjct: 1483 NPCLGQVVRE-VIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGS 1541
Query: 451 TCIDLVD-DFHCACAA 465
+ ++ V+ C C A
Sbjct: 1542 SFVEEVERHLECGCLA 1557
Score = 62.5 bits (145), Expect = 7e-09
Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGG 421
C HG D CEC GWTGP C ++ D C G G C T
Sbjct: 1374 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG---------KCVATGTS 1424
Query: 422 YSCACLAGWTGRDCETNVDD---CTG-QCLHGATCIDLVDDFHCACAAGYAGRTC 472
Y C C G+ G C+ D C+ +C HG I + +C C G++G C
Sbjct: 1425 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1479
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 28/141 (19%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRC---------DRPGDCDCRPGWRGELCS----QCQ 244
C P + G+ C++ + + C P C D+ C+C PG+ G+LC C
Sbjct: 1058 CPPNYTGELCDEVI--DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV 1115
Query: 245 PYPGCKHG-YCNGS--SWDCTCDTNWGGILCDQ-------DLNYCGTHEPCQHGGTCENT 294
+ C+HG C + + CTC + G C+ + C +E CQ+G C
Sbjct: 1116 AHK-CRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYE-CQNGAQCI-V 1172
Query: 295 APDQYFCRCAEGFSGVDCERV 315
+ CRC GF+G CE++
Sbjct: 1173 VQQEPTCRCPPGFAGPRCEKL 1193
Score = 48.4 bits (110), Expect = 1e-04
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 198 CLPGWQGDNCEK----PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC-------SQC 243
C PGW G C++ P CH HG+C G C C G+ G+LC + C
Sbjct: 1391 CRPGWTGPLCDQEARDPCLGHRCH--HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1448
Query: 244 QPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
+ C HG C+ S C C + G C Q+ PC E + +
Sbjct: 1449 SAFK-CHHGQCHISDQGEPYCLCQPGFSGEHCQQE-------NPCLGQVVREVIRRQKGY 1500
Query: 301 CRCAEGFSGVDCERVDNPCAPQPC 324
CA S V C PQ C
Sbjct: 1501 ASCATA-SKVPIMECRGGCGPQCC 1523
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 633 CGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C CR G TG LC+ D C C +G +CV +MC+C G+ G+ C
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC 1438
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC---VGGSGWWMCECVAG 676
GTC + + C C G C + ++ C +PC++GG C + C C G
Sbjct: 965 GTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLG 1023
Query: 677 WTGETCAV 684
+ G+ C +
Sbjct: 1024 FEGQRCEI 1031
Score = 37.5 bits (83), Expect = 0.24
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 7/60 (11%)
Query: 630 GWACGCREGRTGALCE-------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G+ C C +G +G CE L C C+NG +C+ C C G+ G C
Sbjct: 1131 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1190
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCEL---SLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
G C+ A + C C EG G LC+ S + C + C +G + G C C G
Sbjct: 1416 GKCV--ATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPG 1473
Query: 677 WTGETC 682
++GE C
Sbjct: 1474 FSGEHC 1479
Score = 36.3 bits (80), Expect = 0.54
Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 8/58 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C +G + C C PGWTG C Q A R C RC G C GT
Sbjct: 1374 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEA---RDPCL-----GHRCHHGKCVATGT 1423
>BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 167 bits (405), Expect = 2e-40
Identities = 82/229 (35%), Positives = 102/229 (44%), Gaps = 15/229 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
C+ V C A PC N C +T Y C C +TG C
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 151 bits (365), Expect = 2e-35
Identities = 79/222 (35%), Positives = 97/222 (43%), Gaps = 23/222 (10%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
+CA SPC NG C Q Y C C P +TG C ++ A
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 249
Score = 140 bits (340), Expect = 2e-32
Identities = 79/234 (33%), Positives = 101/234 (43%), Gaps = 21/234 (8%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAE 391
C C G+ AS PC +G +C H + C C +TG C +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVK 246
Score = 118 bits (284), Expect = 1e-25
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/228 (28%), Positives = 91/228 (39%), Gaps = 24/228 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDDGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 70.5 bits (165), Expect = 3e-11
Identities = 62/209 (29%), Positives = 79/209 (37%), Gaps = 30/209 (14%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
PC N G C G + C C AG+ +TC+
Sbjct: 178 PCENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 167 bits (405), Expect = 2e-40
Identities = 82/229 (35%), Positives = 102/229 (44%), Gaps = 15/229 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
C+ V C A PC N C +T Y C C +TG C
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 151 bits (365), Expect = 2e-35
Identities = 79/222 (35%), Positives = 97/222 (43%), Gaps = 23/222 (10%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
+CA SPC NG C Q Y C C P +TG C ++ A
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 249
Score = 140 bits (340), Expect = 2e-32
Identities = 79/234 (33%), Positives = 101/234 (43%), Gaps = 21/234 (8%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAE 391
C C G+ AS PC +G +C H + C C +TG C +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVK 246
Score = 118 bits (284), Expect = 1e-25
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/228 (28%), Positives = 91/228 (39%), Gaps = 24/228 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDDGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 70.5 bits (165), Expect = 3e-11
Identities = 62/209 (29%), Positives = 79/209 (37%), Gaps = 30/209 (14%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
PC N G C G + C C AG+ +TC+
Sbjct: 178 PCENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 167 bits (405), Expect = 2e-40
Identities = 82/229 (35%), Positives = 102/229 (44%), Gaps = 15/229 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
C+ V C A PC N C +T Y C C +TG C
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 151 bits (365), Expect = 2e-35
Identities = 79/222 (35%), Positives = 97/222 (43%), Gaps = 23/222 (10%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
+CA SPC NG C Q Y C C P +TG C ++ A
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 249
Score = 140 bits (340), Expect = 2e-32
Identities = 79/234 (33%), Positives = 101/234 (43%), Gaps = 21/234 (8%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAE 391
C C G+ AS PC +G +C H + C C +TG C +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVK 246
Score = 118 bits (284), Expect = 1e-25
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/228 (28%), Positives = 91/228 (39%), Gaps = 24/228 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDDGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 70.5 bits (165), Expect = 3e-11
Identities = 62/209 (29%), Positives = 79/209 (37%), Gaps = 30/209 (14%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
PC N G C G + C C AG+ +TC+
Sbjct: 178 PCENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>U15979-1|AAA75364.1| 382|Homo sapiens dlk protein.
Length = 382
Score = 166 bits (404), Expect = 3e-40
Identities = 82/229 (35%), Positives = 102/229 (44%), Gaps = 15/229 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
C+ V C A PC N C +T Y C C +TG C
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 153 bits (372), Expect = 2e-36
Identities = 80/222 (36%), Positives = 98/222 (44%), Gaps = 23/222 (10%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + GG Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
+CA SPC NG C Q Y C C P +TG C ++ A
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 249
Score = 143 bits (347), Expect = 2e-33
Identities = 80/234 (34%), Positives = 102/234 (43%), Gaps = 21/234 (8%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C +G ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAE 391
C C G+ AS PC +G +C H + C C +TG C +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVK 246
Score = 115 bits (277), Expect = 7e-25
Identities = 67/216 (31%), Positives = 88/216 (40%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/228 (28%), Positives = 91/228 (39%), Gaps = 24/228 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDGGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 72.1 bits (169), Expect = 9e-12
Identities = 62/208 (29%), Positives = 77/208 (37%), Gaps = 28/208 (13%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C GW G+ C RD + CS CAN GTCV +G
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDGGL-YECSCAPG 118
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSSP 655
D Q GGTC+ A C C G +G CE+ + C +P
Sbjct: 119 YSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNP 178
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G C G + C C AG+ +TC+
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 163 bits (396), Expect = 3e-39
Identities = 167/568 (29%), Positives = 207/568 (36%), Gaps = 106/568 (18%)
Query: 190 CTPD-GDKHCLPGWQGDNCEK--------PVCKEGCHPTH-GRCD-RPGDCDCRPGWRGE 238
C P+ G CLPG+ G C+ P C+ C + G C G C C PGW G
Sbjct: 870 CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGF 929
Query: 239 LCSQ-CQPY---PGCKH--------GYCNGSSWDCTCDTNWGGILCDQDLNY------CG 280
C + C P C H G C+ S C C+ + G C+Q C
Sbjct: 930 SCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE 989
Query: 281 THEPCQHGGTCEN-----TAPDQY---FCR--CAEGFSGVDCERVDNPCAPQPC--AHGT 328
CQHG C++ T P + FC C GF G+DC N A C +G+
Sbjct: 990 QLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS 1049
Query: 329 CSLAGTTRGFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
C RG C TC G C +GASC D + G C CA GW G
Sbjct: 1050 CLCPAGRRGPRCAETCPAHTYGHNCSQACA------CFNGASC-DPVHG-QCHCAPGWMG 1101
Query: 387 PACAEDVDE-CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV--DDCT 443
P+C + G + L C N C+ +G CAC GW G CE D
Sbjct: 1102 PSCLQACPAGLYGDNCRHSCL--CQNGGTCDPVSG--HCACPEGWAGLACEKECLPRDVR 1157
Query: 444 GQCLHGATCID--LVDDF--HCACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVD 492
C H C++ L D C C AG+ G C + CA R C C
Sbjct: 1158 AGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHH 1217
Query: 493 LLNAYRCICPVGFSGTNCEDD------RDHCAGS-PC-GNGAACYTAQSDYYCHCAPGWT 544
+ A C CP GF+G+ CE + CA C G AC+ A C CA G+
Sbjct: 1218 VTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCAAGYH 1273
Query: 545 GKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX-------- 596
G +C QR R + C C NGG+C G+ R
Sbjct: 1274 GPSCQQRCPPGRYGPGC----EQLCG---CLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1326
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCREGRTGALCELSLDLCGSS 654
+ GTCL G C GC + R G CE C
Sbjct: 1327 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE---HTCS-- 1381
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
CRNGG C +G C C GWTG C
Sbjct: 1382 -CRNGGLCHASNG--SCSCGLGWTGRHC 1406
Score = 136 bits (330), Expect = 3e-31
Identities = 162/585 (27%), Positives = 203/585 (34%), Gaps = 94/585 (16%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--------PVCKEG 215
C ++ C+ P + GH SC G C G+ G CE+ P C++
Sbjct: 935 CDTGHWGPDCS---HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQL 991
Query: 216 CHPTHGR-CDR-PGDCDCRPGWRGELCSQ----------CQPYPGCKHGY-CNGSSWDCT 262
C HG CD G C C GWRG C C+ C G C+ + C
Sbjct: 992 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCL 1051
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDC-ERVDNP 318
C G C + C C N A P C CA G+ G C +
Sbjct: 1052 CPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAG 1111
Query: 319 CAPQPCAHGT-CSLAGTTRGFT--CTCDRGWGGXX-------XXXXXXXXASGPCLHGAS 368
C H C GT + C C GW G SG CL+G
Sbjct: 1112 LYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL 1171
Query: 369 CRDHLDGFTCECADGWTGPACAED-VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
C H C C GWTG C + G + + C AAAC++ G +C C
Sbjct: 1172 CDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC--SCPPAAACHHVTG--ACRCP 1225
Query: 428 AGWTGRDCETNV------DDCTGQCL---HGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G+TG CE +DC C C C+CAAGY G +C
Sbjct: 1226 PGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCAAGYHGPSCQQRCPP 1283
Query: 479 CAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCE---------DDRDHCAGSPC 522
P C NGG C A C CP GF GT+C + H G C
Sbjct: 1284 GRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG--C 1339
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE-GMC-ANGGTC 580
G GAAC C C PG G C + ++R V E + C G+C A+ G+C
Sbjct: 1340 GQGAACDPVTGT--CLCPPGRAGVRCERGCPQNR--FGVGCEHTCSCRNGGLCHASNGSC 1395
Query: 581 VREEG-SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCRE 637
G + R + A GTC G AC C
Sbjct: 1396 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP 1455
Query: 638 GRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G GA C+ LC C++G C SG C C AG+ G C
Sbjct: 1456 GFHGAGCQ---GLCW---CQHGAPCDPISG--RCLCPAGFHGHFC 1492
Score = 133 bits (322), Expect = 3e-30
Identities = 120/417 (28%), Positives = 165/417 (39%), Gaps = 72/417 (17%)
Query: 194 GDKHCLPGWQGDNCEKPV--------CKEGCHPTH--GRCD-RPGDCDCRPGWRGELCSQ 242
G C PG G++CE C+E C RCD G C C PG+ G C
Sbjct: 831 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD 890
Query: 243 CQPY----PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
P P C+ G+C+ ++ C+C W G C + + C H C
Sbjct: 891 VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC 950
Query: 292 E--NTAPDQY--FCRCAEGFSGVDCERVD-----NPCAPQPCAHGTCSLAGTTRGFTCTC 342
+ + D C C G+ G CE+ P Q C + G CTC
Sbjct: 951 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSG-ACTC 1009
Query: 343 DRGWGGXXXXXXXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
GW G G C GA+C D ++G +C C G GP CAE
Sbjct: 1010 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAETCPA 1067
Query: 396 CS-GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV------DDCTGQCL- 447
+ G + ++ C N A+C+ G C C GW G C D+C CL
Sbjct: 1068 HTYGHNCSQACA--CFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLC 1123
Query: 448 -HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP----CTNGGECVD--LLNAY--R 498
+G TC D V HCAC G+AG C +C PR C + G C++ L + + R
Sbjct: 1124 QNGGTC-DPVSG-HCACPEGWAGLACE---KECLPRDVRAGCRHSGGCLNGGLCDPHTGR 1178
Query: 499 CICPVGFSGTNCEDD-RDHCAGSPCGNGAACYTAQSDYY----CHCAPGWTGKNCTQ 550
C+CP G++G C+ G C +C A + ++ C C PG+TG C Q
Sbjct: 1179 CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQ 1235
Score = 125 bits (302), Expect = 7e-28
Identities = 159/589 (26%), Positives = 200/589 (33%), Gaps = 99/589 (16%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEGC 216
C P+ + C+ C ++ G + G C PG G NCE C++ C
Sbjct: 630 CPPDTFGKNCSFSCSCQN---GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKC 686
Query: 217 H-PTHGRCDR-PGDCDCRPGWRGELCS-QCQPY---PGCKH---------GYCNGSSWDC 261
+ GRC R G C C PG G C C P+ PGC C+ C
Sbjct: 687 NCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSC 746
Query: 262 TCDTNWGGILC--DQDLNY----CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+C + G C + +L Y C C G C++ + + RC GF G DC +
Sbjct: 747 SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS-GECGKRCPAGFQGEDCGQE 805
Query: 316 DNPCAPQPCAHGTCSLAGT-TRGFT--CTCDRGWGGXXXXXXXXXXASG--------PCL 364
+CS G G T C C G G G C
Sbjct: 806 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQ 865
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
H A C D G C C G+ G C +DV + C N C+ G C
Sbjct: 866 HAARC-DPETG-ACLCLPGFVGSRC-QDVCPAGWYGPSCQTRCSCANDGHCHPATG--HC 920
Query: 425 ACLAGWTGRDCETNVD------DCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
+C GWTG C+ D DC+ C G D + C C AGY G C
Sbjct: 921 SCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQC 979
Query: 477 DDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPC 522
P C +G C + A C CP G+ GT CE D + C
Sbjct: 980 PQGHFGPGCEQLCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNC 1037
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCV 581
GAAC C C G G C + TC C++ C NG +C
Sbjct: 1038 TAGAACDAVNGS--CLCPAGRRGPRCAE-------TCPAHT-YGHNCSQACACFNGASCD 1087
Query: 582 REEGSWR-XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
G Q GGTC P + C C EG
Sbjct: 1088 PVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVS----GHCACPEGWA 1143
Query: 641 GALCE---LSLDL---C-GSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G CE L D+ C S C NGG C +G C C AGWTG+ C
Sbjct: 1144 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKC 1190
Score = 120 bits (288), Expect = 3e-26
Identities = 130/457 (28%), Positives = 163/457 (35%), Gaps = 85/457 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFG--HYS-CTPDG--DKH-----CLPGWQGDNCEKP---- 210
C + C C PRD + G H C G D H C GW GD C+ P
Sbjct: 1138 CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRG 1197
Query: 211 ----VCKE--------GCHPTHGRCDRP-----GDCD--CRPGWRGELCSQCQPYPGCKH 251
C + CH G C P C+ C PG GE C+Q PG ++
Sbjct: 1198 WFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPG-EN 1256
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDL---NY---CGTHEPCQHGGTCENTAPDQYFCRCAE 305
C+ ++ C+C + G C Q Y C C +GG+C+ CRC
Sbjct: 1257 PACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA---CRCPT 1313
Query: 306 GFSGVDCERVD-----NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
GF G DC P C G + G TC C G G
Sbjct: 1314 GFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNRF 1372
Query: 361 GP-CLHGASCRD----HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG-PCVNAAA 414
G C H SCR+ H +C C GWTG C ++ GR L C N +
Sbjct: 1373 GVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHC--ELACPPGRYGAACHLECSCHNNST 1430
Query: 415 CNNTAGGYSCACLAGWTGRDCETNVDD------CTGQCL--HGATCIDLVDDFHCACAAG 466
C G +C C G+ G+ CE C G C HGA C D + C C AG
Sbjct: 1431 CEPATG--TCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPC-DPISG-RCLCPAG 1486
Query: 467 YAGRTCSLDVDD------CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
+ G C + C R +GG D + C+CP G SG C D
Sbjct: 1487 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL-CLCPPGRSGATCNLDCRRGQFG 1545
Query: 521 P-------CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
P CG GA C CHC G+ G C +
Sbjct: 1546 PSCTLHCDCGGGADCDPVSGQ--CHCVDGYMGPTCRE 1580
Score = 116 bits (278), Expect = 6e-25
Identities = 125/460 (27%), Positives = 157/460 (34%), Gaps = 81/460 (17%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKEG 215
C + Y C+ C F SC P G HC PGW G +C + C+
Sbjct: 1065 CPAHTYGHNCSQACAC----FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHS 1120
Query: 216 CHPTHG-RCDR-PGDCDCRPGWRGELCS-QCQPYP---GCKH-------GYCNGSSWDCT 262
C +G CD G C C GW G C +C P GC+H G C+ + C
Sbjct: 1121 CLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCL 1180
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF---CRCAEGFSGVDCERVDNPC 319
C W G C E C +C A + CRC GF+G CE+ P
Sbjct: 1181 CPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQACPPG 1240
Query: 320 A-PQPCAHGTCSLAGTTRGF-----TCTCDRGWGGXXXXXXXXXXASGP-------CLHG 366
+ + CA C G TC+C G+ G GP CL+G
Sbjct: 1241 SFGEDCAQ-MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNG 1299
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
SC D G C C G+ G C + G C AAC+ G +C C
Sbjct: 1300 GSC-DAATG-ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTG--TCLC 1354
Query: 427 LAGWTGRDCETNVDD------C--TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
G G CE C T C +G C + C+C G+ GR C L
Sbjct: 1355 PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH--ASNGSCSCGLGWTGRHCELACPP 1412
Query: 479 ------CAPR-PCTNGGECVDLLNAYRC-----------ICPVGFSGTNCEDDRDHCAGS 520
C C N C RC CP GF G C+ G+
Sbjct: 1413 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGA 1472
Query: 521 PC---GNGAACYTAQSDYYCH--CAPGWTGKNCTQRAARD 555
PC C ++C C PG G+ C QR D
Sbjct: 1473 PCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD 1512
Score = 115 bits (277), Expect = 7e-25
Identities = 119/369 (32%), Positives = 142/369 (38%), Gaps = 65/369 (17%)
Query: 232 RPGWRGELCSQCQPYPGCKHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGTHE-PCQHGG 289
+P G L ++C G C GS+ C C + G C D++ C TH CQH
Sbjct: 192 QPDEEGCLSAECSAGLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH-- 249
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDNPCA--PQPCAHGTCSLAGTTRGFTCTCD 343
C NT P Y C C GF C + N CA C H L T C C
Sbjct: 250 RCVNT-PGSYLCECKPGFRLHTDSRTCLAI-NSCALGNGGCQHHCVQL--TITRHRCQCR 305
Query: 344 RGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW----TGPACAEDVD 394
G+ G +G C+H C+ CEC G+ G AC EDVD
Sbjct: 306 PGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADGKAC-EDVD 362
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDC---ETN-VDDC---T 443
EC+ L C A C NT G + C C AG+ GR C E V+ C
Sbjct: 363 ECA------AGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN 414
Query: 444 GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
G C HG C C C GY RTC +DVDDCA PC C + Y C
Sbjct: 415 GGCSHG--CSHTSAGPLCTCPRGYELDTDQRTC-IDVDDCADSPCCQ-QVCTNNPGGYEC 470
Query: 500 ICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
C G+ G CE D D CA S G C + C C G+ R D
Sbjct: 471 GCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQCSCEAGY-------RLHED 522
Query: 556 RKTCSVLVE 564
R+ CS L E
Sbjct: 523 RRGCSPLEE 531
Score = 103 bits (247), Expect = 3e-21
Identities = 130/448 (29%), Positives = 160/448 (35%), Gaps = 84/448 (18%)
Query: 165 CQPNYYNTTCTTFCRPR-----DDKFGHYSCTPDG------DKHCLPGWQGDNCEKPV-C 212
C Y C C + D GH +C P+G +K CLP C C
Sbjct: 1108 CPAGLYGDNCRHSCLCQNGGTCDPVSGHCAC-PEGWAGLACEKECLPRDVRAGCRHSGGC 1166
Query: 213 KEG--CHPTHGRCDRP----GD-CD--CRPGWRGELCSQ---CQPYPGCKHGYCNGSSWD 260
G C P GRC P GD C C GW GE C+Q C P C H G+
Sbjct: 1167 LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHH--VTGA--- 1221
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC--ENTA--PDQYFCRCAEGFSGVDCERVD 316
C C + G C+Q E C C EN A P C CA G+ G C++
Sbjct: 1222 CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRC 1281
Query: 317 NPCAPQPCAHGTCSL--AGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-CLH------ 365
P P C G+ T C C G+ G GP C H
Sbjct: 1282 PPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQ 1341
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
GA+C D + G TC C G G C + E C N C+ + G SC+
Sbjct: 1342 GAAC-DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNGGLCHASNG--SCS 1396
Query: 426 CLAGWTGRDCETNVDD------CTGQCL--HGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
C GWTGR CE C +C + +TC C C G+ G+ C
Sbjct: 1397 CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGT--CRCGPGFYGQACE---H 1451
Query: 478 DCAPRP----------CTNGGECVDLLNAYRCICPVGFSGTNCE------DDRDHC-AGS 520
C P C +G C D ++ RC+CP GF G CE + C
Sbjct: 1452 PCPPGFHGAGCQGLCWCQHGAPC-DPISG-RCLCPAGFHGHFCERGCEPGSFGEGCHQRC 1509
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C GA C C C PG +G C
Sbjct: 1510 DCDGGAPCDPVTG--LCLCPPGRSGATC 1535
Score = 95.1 bits (226), Expect = 1e-18
Identities = 136/477 (28%), Positives = 171/477 (35%), Gaps = 109/477 (22%)
Query: 190 CTPDGDK--HCLPGWQGDNCEKPVCKEGCHPTHGRC-----DRPGD--CDCRPGWRGELC 240
C P + HC PG+QG C+ V + C +G C + PG C+C+PG+R
Sbjct: 214 CVPGSAQPCHCPPGFQGPRCQYDV--DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTD 271
Query: 241 SQ-CQPYPGCK--HGYCNGSSWDCTCDTN----WGGILCDQDLNYCGTHEPC-QHGGTCE 292
S+ C C +G C T + G +D +C PC G+C
Sbjct: 272 SRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCM 331
Query: 293 N---TAPDQYFCRCAEGF----SGVDCERVDNPCAP--QPCAHGTCSLAGTTRGFTCTCD 343
+ C C G+ G CE VD CA CAHG + G+ F C C
Sbjct: 332 HRCQVVRGLARCECHVGYQLAADGKACEDVDE-CAAGLAQCAHGCLNTQGS---FKCVCH 387
Query: 344 RGW--GG--------XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW---TGPACA 390
G+ G +G C HG C G C C G+ T
Sbjct: 388 AGYELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTC 445
Query: 391 EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCT--- 443
DVD+C A PC C N GGY C C AG+ G CE +VD+C
Sbjct: 446 IDVDDC--------ADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSR 495
Query: 444 GQCLHGATCIDLVDDFHCACAAGYA----GRTCS------LDVDDCAP--RPCTNGGECV 491
G C H C +L F C+C AGY R CS +D+D P RP +
Sbjct: 496 GGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQ 553
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDH-------CA----GSPCG-------NGAACYTAQS 533
D L VG E +H C G C NG C
Sbjct: 554 DELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLD 613
Query: 534 DYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
C C GWTG C + D K CS C+ C NGGTC G+ R
Sbjct: 614 G--CDCPEGWTGLICNETCPPDTFGKNCSF------SCS---CQNGGTCDSVTGACR 659
Score = 91.5 bits (217), Expect = 1e-17
Identities = 106/357 (29%), Positives = 134/357 (37%), Gaps = 70/357 (19%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
CDC GW G +C++ P P C S+ C+C GG CD C P G
Sbjct: 615 CDCPEGWTGLICNETCP-PDTFGKNC---SFSCSCQN--GG-TCDSVTGACRC-PPGVSG 666
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
CE+ C +G+ G C + N CA + H L G C CD G G
Sbjct: 667 TNCED--------GCPKGYYGKHCRKKCN-CANRGRCH---RLYG-----ACLCDPGLYG 709
Query: 349 XXXXXXXXXXASGP-------CL--HGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
A GP C+ H SC D DG +C C G+ G C EC
Sbjct: 710 RFCHLTCPPWAFGPGCSEECQCVQPHTQSC-DKRDG-SCSCKAGFRGERCQA---ECELG 764
Query: 400 SMTEGALGPCV--NAAACNNTAGGYSCACLAGWTGRDC--ETNVD----DCTGQC-LHGA 450
G C AC++ +G C AG+ G DC E V +C+ C GA
Sbjct: 765 YFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGA 824
Query: 451 TCIDLVDDFHCACAAGYAGRTCSLDVDD------CAP--RPCTNGGECVDLLNAYRCICP 502
C + C C G G C D + C C + C A C+C
Sbjct: 825 PCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCL 880
Query: 503 VGFSGTNCED------DRDHC-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
GF G+ C+D C C N C+ A +C CAPGWTG +C QRA
Sbjct: 881 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSC-QRA 934
Score = 90.2 bits (214), Expect = 3e-17
Identities = 130/504 (25%), Positives = 163/504 (32%), Gaps = 87/504 (17%)
Query: 261 CTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C C W G++C++ C CQ+GGTC++ CRC G SG +CE
Sbjct: 615 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA---CRCPPGVSGTNCED 671
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGP-------C 363
C+ A R C CD G G A GP C
Sbjct: 672 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 731
Query: 364 L--HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN--AAACNNTA 419
+ H SC D DG +C C G+ G C EC G C AC++ +
Sbjct: 732 VQPHTQSC-DKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVS 786
Query: 420 GGYSCACLAGWTGRDC--ETNVD----DCTGQC-LHGATCIDLVDDFHCACAAGYAGRTC 472
G C AG+ G DC E V +C+ C GA C + C C G G C
Sbjct: 787 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ--CRCPPGRTGEDC 844
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
D C G + ICP C+ + C P G+ C
Sbjct: 845 EAD--------CPEGRWGLGCQE----ICPACQHAARCDPETGACLCLPGFVGSRCQDV- 891
Query: 533 SDYYCHCAPGWTGKNCTQRAA-RDRKTCSVLVEESERCAEGMCANGGTCVR--EEGSWRX 589
C GW G +C R + + C CA G G +C R + G W
Sbjct: 892 ------CPAGWYGPSCQTRCSCANDGHCHPATGHCS-CAPGW--TGFSCQRACDTGHW-- 940
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG--CREGRTGALCELS 647
D G CL A G C C +G G CE
Sbjct: 941 ---------GPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE-- 989
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXX 707
LC C++G C SG C C AGW G C
Sbjct: 990 -QLC---QCQHGAACDHVSG--ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 1043
Query: 708 XXXSSTRCLCPAPPQRAARRCLET 731
+ + CLCPA R RC ET
Sbjct: 1044 DAVNGS-CLCPA--GRRGPRCAET 1064
Score = 79.4 bits (187), Expect = 6e-14
Identities = 96/361 (26%), Positives = 126/361 (34%), Gaps = 53/361 (14%)
Query: 342 CDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C RGW ++G C HG C C C G+ GP C DVDEC
Sbjct: 185 CCRGWMQQPDEEGCLSAECSAGLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDECRTH 243
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDC---TGQCLHGATC 452
+ G C + C NT G Y C C G+ R C ++ C G C H C
Sbjct: 244 N------GGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCALGNGGCQH--HC 292
Query: 453 IDLVDDFH-CACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF-- 505
+ L H C C G+ GR C + CA R + C + RC C VG+
Sbjct: 293 VQLTITRHRCQCRPGFQLQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 351
Query: 506 --SGTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G CED + AG + C +G C Q + C C G+ + A R+ +
Sbjct: 352 AADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGY------ELGADGRQCYRIE 403
Query: 563 VEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+E C AN G C G C
Sbjct: 404 MEIVNSCE----ANNGGC--SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCC 457
Query: 623 --LPSALPPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+ + P G+ CGC G G CE +D C SS C +G + C C AG
Sbjct: 458 QQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQCSCEAG 516
Query: 677 W 677
+
Sbjct: 517 Y 517
Score = 64.9 bits (151), Expect = 1e-09
Identities = 79/282 (28%), Positives = 99/282 (35%), Gaps = 48/282 (17%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDV--DDC 479
CL G DC DDC +G TC+ +D C C G+ G TC D +C
Sbjct: 586 CLDDSFGHDCSLTCDDCR----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNC 639
Query: 480 A-PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD------RDHCAGS-PCGNGAACYTA 531
+ C NGG C + A C CP G SGTNCED HC C N C+
Sbjct: 640 SFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 697
Query: 532 QSDYYCHCAPGWTGKNCTQR------AARDRKTCSVLVEESERC--AEGMCA-NGGTCVR 582
C C PG G+ C + C + ++ C +G C+ G R
Sbjct: 698 YG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG--FR 753
Query: 583 EEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG--CREGRT 640
E + + G C P+ G CG C G
Sbjct: 754 GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRC-PAGF-QGEDCGQECPVGTF 811
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G C S CG +PC G +G C C G TGE C
Sbjct: 812 GVNCSSSCS-CGGAPCH------GVTG--QCRCPPGRTGEDC 844
Score = 32.7 bits (71), Expect = 6.7
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C + C +GGRCV GS C C G+ G C
Sbjct: 203 CSAGLCFHGGRCVPGSA-QPCHCPPGFQGPRC 233
>Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein
protein.
Length = 383
Score = 162 bits (394), Expect = 5e-39
Identities = 81/229 (35%), Positives = 100/229 (43%), Gaps = 15/229 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C GW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCHVGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
C+ V C A PC N C +T Y C C +TG C
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 153 bits (370), Expect = 4e-36
Identities = 80/222 (36%), Positives = 98/222 (44%), Gaps = 23/222 (10%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCHVGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + GG Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
+CA SPC NG C Q Y C C P +TG C ++ A
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 249
Score = 139 bits (337), Expect = 4e-32
Identities = 79/234 (33%), Positives = 101/234 (43%), Gaps = 21/234 (8%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C GWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCHVGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C +G ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD-GFTCECADGWTGPACAE 391
C C G+ AS PC +G +C H + C C +TG C +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVK 246
Score = 114 bits (274), Expect = 2e-24
Identities = 67/216 (31%), Positives = 88/216 (40%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCHVGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/228 (28%), Positives = 91/228 (39%), Gaps = 24/228 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCHVGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDGGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 74.1 bits (174), Expect = 2e-12
Identities = 63/208 (30%), Positives = 78/208 (37%), Gaps = 28/208 (13%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C VG+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCHVGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C GW G+ C RD + CS CAN GTCV +G
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDGGL-YECSCAPG 118
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSSP 655
D Q GGTC+ A C C G +G CE+ + C +P
Sbjct: 119 YSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNP 178
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G C G + C C AG+ +TC+
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>U15981-1|AAA75365.1| 310|Homo sapiens dlk protein.
Length = 310
Score = 158 bits (383), Expect = 1e-37
Identities = 79/223 (35%), Positives = 99/223 (44%), Gaps = 15/223 (6%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAG 429
C+ V C A PC N C +T G C + G
Sbjct: 204 TCSRPVTNC--------ASSPCQNGGTCLQHTQGQAICFTILG 238
Score = 138 bits (333), Expect = 1e-31
Identities = 71/196 (36%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + GG Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 513 DRDHCAGSPCGNGAAC 528
+CA SPC NG C
Sbjct: 208 PVTNCASSPCQNGGTC 223
Score = 137 bits (332), Expect = 2e-31
Identities = 76/217 (35%), Positives = 95/217 (43%), Gaps = 20/217 (9%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C +G ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG 375
C C G+ AS PC +G +C H G
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQG 229
Score = 121 bits (292), Expect = 1e-26
Identities = 71/210 (33%), Positives = 93/210 (44%), Gaps = 27/210 (12%)
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWG 347
G CE D CRC G+ G C++ C P C HG C G C C GW
Sbjct: 35 GFCE----DDNVCRCQPGWQGPLCDQ----CVTSPGCLHGLCGEPGQ-----CICTDGWD 81
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDG--FTCECADGWTGPACAEDVDECSGRSMTEGA 405
G +S PC + +C LDG + C CA G++G C + C + G+
Sbjct: 82 GELCDRDVRACSSAPCANNGTCVS-LDGGLYECSCAPGYSGKDCQKKDGPC----VINGS 136
Query: 406 LGPCVNAAAC---NNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHC 461
PC + C A SC C G++G CE + CT C + C D+ DF C
Sbjct: 137 --PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRC 194
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
C AG+ +TCS V +CA PC NGG C+
Sbjct: 195 RCPAGFIDKTCSRPVTNCASSPCQNGGTCL 224
Score = 115 bits (277), Expect = 7e-25
Identities = 67/216 (31%), Positives = 88/216 (40%), Gaps = 36/216 (16%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
C++ CA C NGGTC++
Sbjct: 204 TCSRPVTN--------------CASSPCQNGGTCLQ 225
Score = 85.4 bits (202), Expect = 9e-16
Identities = 61/222 (27%), Positives = 88/222 (39%), Gaps = 24/222 (10%)
Query: 457 DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH 516
DD C C G+ G C D C P G C + +CIC G+ G C+ D
Sbjct: 39 DDNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQCICTDGWDGELCDRDVRA 91
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 92 CSSAPCANNGTCVSLDGGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 139
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 140 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 196
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGS-GWWMCECVAG 676
G C + C SSPC+NGG C+ + G +C + G
Sbjct: 197 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQGQAICFTILG 238
Score = 72.1 bits (169), Expect = 9e-12
Identities = 62/208 (29%), Positives = 77/208 (37%), Gaps = 28/208 (13%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXX 596
C C GW G+ C RD + CS CAN GTCV +G
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDGGL-YECSCAPG 118
Query: 597 XXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSSP 655
D Q GGTC+ A C C G +G CE+ + C +P
Sbjct: 119 YSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNP 178
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G C G + C C AG+ +TC+
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens
cDNA FLJ90584 fis, clone PLACE1000740, highly similar to
Neurogenic locus notch homolog protein 2 precursor. ).
Length = 269
Score = 154 bits (373), Expect = 2e-36
Identities = 78/215 (36%), Positives = 102/215 (47%), Gaps = 16/215 (7%)
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTC 340
+EPC + G C +C+C EGFSG C+ D PC C +G TC TC
Sbjct: 32 YEPCVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATC 90
Query: 341 TCDRGWGGXXXXXXXXX--XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECS 397
C G+ G S PCL+G +C D + C C G+TG C + D C
Sbjct: 91 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACL 149
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDL 455
PC N + C A +SC CL G+TG+ CET+V++C G C HG TC++L
Sbjct: 150 SH--------PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
+ C C G+ G+ C CAP PC NGG C
Sbjct: 202 PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 236
Score = 132 bits (320), Expect = 5e-30
Identities = 73/227 (32%), Positives = 106/227 (46%), Gaps = 16/227 (7%)
Query: 322 QPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDGFTC 378
+PC + G C G+ C C G+ G + C +G +C + L TC
Sbjct: 33 EPCVNEGMCVTYHNGTGY-CKCPEGFSGEYCQHRDPCEKNR-CQNGGTCVAQAMLGKATC 90
Query: 379 ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCET 437
CA G+TG C S PC+N C+ + Y C C G+TG++C+
Sbjct: 91 RCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSRDTYECTCQVGFTGKECQW 144
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC-APRPCTNGGECVDLLN 495
D C C +G+TC + + F C C G+ G+ C DV++C P C +GG C++L
Sbjct: 145 T-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPG 203
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYYCHCAP 541
+Y+C C GF+G C+ CA SPC NG C T + C+C P
Sbjct: 204 SYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250
Score = 127 bits (306), Expect = 2e-28
Identities = 76/232 (32%), Positives = 105/232 (45%), Gaps = 29/232 (12%)
Query: 362 PCLHGASCRDHLDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
PC++ C + +G C+C +G++G C + D C G G CV A G
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFSGEYC-QHRDPCEKNRCQNG--GTCVAQAML----G 86
Query: 421 GYSCACLAGWTGRDCETNVDD-C--TGQCLHGATCIDLV-DDFHCACAAGYAGRTCSLDV 476
+C C +G+TG DC+ + C + CL+G TC L D + C C G+ G+ C
Sbjct: 87 KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-T 145
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-AGSPCGNGAACYTAQSDY 535
D C PC NG C + N + C C GF+G CE D + C C +G C Y
Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C C G+TG+ C S+ V CA C NGGTC R+ G +
Sbjct: 206 QCQCLQGFTGQYCD----------SLYVP----CAPSPCVNGGTC-RQTGDF 242
Score = 112 bits (270), Expect = 5e-24
Identities = 64/188 (34%), Positives = 87/188 (46%), Gaps = 22/188 (11%)
Query: 408 PCVNAAACNNTAGGYS-CACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCAC 463
PCVN C G C C G++G C+ D C +C +G TC+ ++ C C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFSGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRC 92
Query: 464 AAGYAGRTCSLDVDD-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGS 520
A+G+ G C C RPC NGG C L + Y C C VGF+G C+ D C
Sbjct: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSH 151
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC NG+ C T + + C C G+TG+ C D C + G C +GGTC
Sbjct: 152 PCANGSTCTTVANQFSCKCLTGFTGQKC----ETDVNECDI---------PGHCQHGGTC 198
Query: 581 VREEGSWR 588
+ GS++
Sbjct: 199 LNLPGSYQ 206
Score = 105 bits (252), Expect = 8e-22
Identities = 72/237 (30%), Positives = 98/237 (41%), Gaps = 29/237 (12%)
Query: 212 CKEGCHP--THGRC----DRPGDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW--- 259
C++G P G C + G C C G+ GE C P C++G C +
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 260 -DCTCDTNWGGILCDQDLNY-CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
C C + + G C ++ C PC +GGTC + D Y C C GF+G +C+ D
Sbjct: 88 ATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD- 146
Query: 318 PCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDG 375
C PCA+G TC+ F+C C G+ G G C HG +C +
Sbjct: 147 ACLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGS 204
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACL-AGW 430
+ C+C G+TG C C A PCVN C T + C CL A W
Sbjct: 205 YQCQCLQGFTGQYCDSLYVPC--------APSPCVNGGTCRQTGDFTFECNCLPATW 253
Score = 103 bits (246), Expect = 4e-21
Identities = 73/240 (30%), Positives = 97/240 (40%), Gaps = 29/240 (12%)
Query: 446 CLHGATCIDLVDDF-HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICP 502
C++ C+ + +C C G++G C D C C NGG CV +L C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFSGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
Query: 503 VGFSGTNCEDDRDH-CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTC 559
GF+G +C+ H C S PC NG C+ D Y C C G+TGK C
Sbjct: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC----------- 142
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ ++ C CANG TC + ++ Q G
Sbjct: 143 ----QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHG 195
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV-AGW 677
GTCL LP + C C +G TG C+ C SPC NGG C G + C C+ A W
Sbjct: 196 GTCLN--LPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPATW 253
Score = 82.2 bits (194), Expect = 8e-15
Identities = 60/204 (29%), Positives = 80/204 (39%), Gaps = 23/204 (11%)
Query: 483 PCTNGGECVDLLNAYR-CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHC 539
PC N G CV N C CP GFSG C+ RD C + C NG C C C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFSGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRC 92
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXX 599
A G+TG++C + C V C NGGTC R
Sbjct: 93 ASGFTGEDCQYSTSHP---CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGF 137
Query: 600 XDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRN 658
G TC + + ++C C G TG CE ++ C C++
Sbjct: 138 TGKECQWTDACLSHPCAN-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQH 194
Query: 659 GGRCVGGSGWWMCECVAGWTGETC 682
GG C+ G + C+C+ G+TG+ C
Sbjct: 195 GGTCLNLPGSYQCQCLQGFTGQYC 218
Score = 72.5 bits (170), Expect = 7e-12
Identities = 46/168 (27%), Positives = 66/168 (39%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G++G+ C R + C + C NGGT
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFSGEYCQHR---------------DPCEKNRCQNGGT 78
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 137
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 138 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184
>BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 153 bits (370), Expect = 4e-36
Identities = 154/526 (29%), Positives = 199/526 (37%), Gaps = 92/526 (17%)
Query: 198 CLPGW--QGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS----------QCQP 245
C PG+ GD C P+C E C HGRC P C C PGW G CS C
Sbjct: 88 CCPGYYENGDFCI-PLCTEEC--VHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
Query: 246 YPGCKHG-YCNGSSWDCTCDTNWGGILCDQDLNYCGTHE-----PCQ--HGGTCENTAPD 297
C++G CN + C C + G C ++L GTH PCQ HG +C+ A +
Sbjct: 145 RCQCQNGALCNPITGACVCAAGFRGWRC-EELCAPGTHGKGCQLPCQCRHGASCDPRAGE 203
Query: 298 QYFCRCAEGFSGVDCERVDNPCA-PQPC-AHGTCSLAGTTRGFT--CTCDRGWGGXXXXX 353
C CA G++GV CE + P + C C GT T C C GW G
Sbjct: 204 ---CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ 260
Query: 354 XXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGA 405
G PC HG C DH+ G C C G+ G C E+ S G ++
Sbjct: 261 PCPPGTFGQNCSQDCPCHHGGQC-DHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQRC 318
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAA 465
C N C+ T G +C C G+ G C+ + C + LHG C C C A
Sbjct: 319 --DCHNGGQCSPTTG--ACECEPGYKGPRCQERL--CP-EGLHGPGC-----TLPCPCDA 366
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
+C C +P +G C + CPVG+ G C+ C NG
Sbjct: 367 DNT-ISCHPVTGACTCQPGWSGHHCNE-------SCPVGYYGDGCQ------LPCTCQNG 412
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVRE 583
A C++ C CAPG+ G+ C A CS + C+ C NGGTC
Sbjct: 413 ADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSI------CS---CNNGGTCSPV 461
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
+GS A G + P +C C G G
Sbjct: 462 DGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA---ACSPIDGSCSCTPGWLGDT 518
Query: 644 CEL-------SLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CEL L+ C + C +G C C+AGWTG C
Sbjct: 519 CELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRC 562
Score = 143 bits (347), Expect = 2e-33
Identities = 167/585 (28%), Positives = 206/585 (35%), Gaps = 130/585 (22%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPD-GDKHCLPGWQGDNCEKPVCKEGCHPTH-- 220
LC P + C C+ R SC P G+ C PG+ G CE+ +C G H H
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGA----SCDPRAGECLCAPGYTGVYCEE-LCPPGSHGAHCE 229
Query: 221 --------GRCDR-PGDCDCRPGWRGELCSQCQPYPG-----------CKHG-YCNGSSW 259
G C G+C C PGW G +C+Q P PG C HG C+ +
Sbjct: 230 LRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP-PGTFGQNCSQDCPCHHGGQCDHVTG 288
Query: 260 DCTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC- 312
C C + G C ++ + C C +GG C +P C C G+ G C
Sbjct: 289 QCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQC---SPTTGACECEPGYKGPRCQ 345
Query: 313 -----ERVDNP-CA-PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
E + P C P PC A T S T CTC GW G G
Sbjct: 346 ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYYGDGC 403
Query: 363 -----CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACN 416
C +GA C G C CA G+ G CA S G GP C + +CN
Sbjct: 404 QLPCTCQNGADCHSITGG--CTCAPGFMGEVCAV--------SCAAGTYGPNCSSICSCN 453
Query: 417 NTAGGY------SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGR 470
N GG SC C GW G DC T C G ++ + C CA G A
Sbjct: 454 N--GGTCSPVDGSCTCKEGWQGLDC-------TLPCPSGTWGLNCNES--CTCANGAA-- 500
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
CS C+ P G C CP G G NC + HC C + C
Sbjct: 501 -CSPIDGSCSCTPGWLGDTC-------ELPCPDGTFGLNCSE---HC---DCSHADGCDP 546
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+C C GWTG C R CSV C+ C NGG+C E+GS
Sbjct: 547 VTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSV------SCS---CENGGSCSPEDGSCE 595
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP---PGWACGCREGRTGALCE 645
Q C+ S+ P C C G +GALC
Sbjct: 596 CAPGFRGPL----CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCN 651
Query: 646 -------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
D C N G C G C+C GW G+ C+
Sbjct: 652 QVCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCS 694
Score = 143 bits (346), Expect = 3e-33
Identities = 129/452 (28%), Positives = 174/452 (38%), Gaps = 88/452 (19%)
Query: 165 CQPNYYNTTCTTFCRPR-DDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKEG 215
C P YY FC P ++ H C HC PGW G +C P C
Sbjct: 88 CCPGYYENG--DFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 216 CHPTHGRCDRP--GDCDCRPGWRG----ELCSQ------CQPYPGCKHG-YCNGSSWDCT 262
C +G P G C C G+RG ELC+ CQ C+HG C+ + +C
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
Query: 263 CDTNWGGILCDQ------DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C + G+ C++ +C PCQ+GGTC + + C C G++G C +
Sbjct: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGE---CACPPGWTGAVCAQ-- 260
Query: 317 NPCAP----QPCAHG-TCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASG-------P 362
PC P Q C+ C G T C C G+ G + G
Sbjct: 261 -PCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCD 319
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNT 418
C +G C CEC G+ GP C E + C G PC N +C+
Sbjct: 320 CHNGGQCSPTTG--ACECEPGYKGPRCQERL--CPEGLHGPGCTLPCPCDADNTISCHPV 375
Query: 419 AGGYSCACLAGWTGRDCETNV------DDC--TGQCLHGATCIDLVDDFHCACAAGYAGR 470
G +C C GW+G C + D C C +GA C + C CA G+ G
Sbjct: 376 TG--ACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGE 431
Query: 471 TCSLDV------DDCAP-RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD------HC 517
C++ +C+ C NGG C + + C C G+ G +C +C
Sbjct: 432 VCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNC 489
Query: 518 AGS-PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
S C NGAAC + D C C PGW G C
Sbjct: 490 NESCTCANGAAC--SPIDGSCSCTPGWLGDTC 519
Score = 135 bits (326), Expect = 8e-31
Identities = 162/599 (27%), Positives = 208/599 (34%), Gaps = 111/599 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
LC P + C C ++ H+ G+ C PGW G C +P C +
Sbjct: 218 LCPPGSHGAHCELRCPCQNGGTCHHIT---GECACPPGWTGAVCAQPCPPGTFGQNCSQD 274
Query: 216 CHPTHG-RCDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
C HG +CD G C C G+ G+ C QC C +G C+ ++ C
Sbjct: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACE 334
Query: 263 CDTNWGGILCDQDLNYCGTHEP-CQHGGTCE--NTA---PDQYFCRCAEGFSGVDCERV- 315
C+ + G C + L G H P C C+ NT P C C G+SG C
Sbjct: 335 CEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESC 394
Query: 316 ------DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP------- 362
D P C +G T G CTC G+ G GP
Sbjct: 395 PVGYYGDGCQLPCTCQNGA-DCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICS 451
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAGG 421
C +G +C +DG +C C +GW G C + G + E C N AAC+ G
Sbjct: 452 CNNGGTCSP-VDG-SCTCKEGWQGLDCTLPCPSGTWGLNCNESCT--CANGAACSPIDG- 506
Query: 422 YSCACLAGWTGRDCETNVDDCTG--------QCLHGATCIDLVDDFHCACAAGYAGRTCS 473
SC+C GW G CE D T C H C + HC C AG+ G C
Sbjct: 507 -SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCD 563
Query: 474 LDVD------DCAPR-PCTNGGECVDLLNAYRC-----------ICPVGFSGTNCEDDRD 515
+C+ C NGG C + C ICP GF G C
Sbjct: 564 STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 623
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGM 573
C S C+ C C PG++G C Q A + C+ L C+
Sbjct: 624 LCVHS----SRPCHHISG--ICECLPGFSGALCNQVCAGGYFGQDCAQL------CS--- 668
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
CAN GTC +GS + G S AC
Sbjct: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA---SCSAEDGAC 725
Query: 634 GCREGRTGALCELSLDL------CGS-SPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C G TG C CG C+NG C SG C C G+TG+ C R
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQR 782
Score = 124 bits (300), Expect = 1e-27
Identities = 120/435 (27%), Positives = 162/435 (37%), Gaps = 92/435 (21%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKEG 215
C Y C++ C + +C+P DG C GWQG +C P C E
Sbjct: 437 CAAGTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNES 492
Query: 216 CHPTHGRCDRP--GDCDCRPGWRGELCS----------QCQPYPGCKHGY-CNGSSWDCT 262
C +G P G C C PGW G+ C C + C H C+ + C
Sbjct: 493 CTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 552
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C W GI CD T P + G C + C C G S C+P+
Sbjct: 553 CLAGWTGIRCDS------TCPPGRWGPNCSVS------CSCENGGS----------CSPE 590
Query: 323 PCAHGTCSLAGTTRGFTCT--CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCEC 380
G+C A RG C C G+ G C+H + H+ G CEC
Sbjct: 591 D---GSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL-----CVHSSRPCHHISGI-CEC 641
Query: 381 ADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETN 438
G++G C + C+G + L C N C+ G SC C GW G+DC
Sbjct: 642 LPGFSGALCNQ---VCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCSQA 696
Query: 439 VDD--CTGQCLHGATCID----LVDDFHCACAAGYAGRTCSLDVD------DCAPR-PCT 485
C H +C + +D C C G+ G C+ DC C
Sbjct: 697 CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ 756
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA----CYTAQS-DYY---C 537
NG C D ++ +C C GF+G +CE CA G G C + D+ C
Sbjct: 757 NGASC-DHISG-KCTCRTGFTGQHCEQ---RCAPGTFGYGCQQLCECMNNSTCDHVTGTC 811
Query: 538 HCAPGWTGKNCTQRA 552
+C+PG+ G C Q A
Sbjct: 812 YCSPGFKGIRCDQAA 826
Score = 120 bits (290), Expect = 2e-26
Identities = 132/451 (29%), Positives = 164/451 (36%), Gaps = 75/451 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--PV------CKE 214
LC + CT C P D SC P G C PGW G +C + PV C+
Sbjct: 348 LCPEGLHGPGCTLPC-PCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL 405
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDC 261
C +G C G C C PG+ GE+C+ C C +G C+ C
Sbjct: 406 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERV--D 316
TC W G+ C C TC N A P C C G+ G CE D
Sbjct: 466 TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPD 525
Query: 317 NPCAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-------CLHGA 367
H CS A T C C GW G GP C +G
Sbjct: 526 GTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYS 423
SC DG +CECA G+ GP C C G PC ++ C++ +G
Sbjct: 586 SCSPE-DG-SCECAPGFRGPLCQRI---CPPGFYGHGCAQPCPLCVHSSRPCHHISG--I 638
Query: 424 CACLAGWTGRDCETNV------DDCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C CL G++G C DC C + TC + D C C G+ G+ CS
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI--DGSCQCFPGWIGKDCSQA 696
Query: 476 VDDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA--GSPCGNGA 526
P C NG C A C C G++G C R A G CG
Sbjct: 697 CPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFCTQ-RCPAAFFGKDCGRVC 753
Query: 527 ACYTAQS-DYY---CHCAPGWTGKNCTQRAA 553
C S D+ C C G+TG++C QR A
Sbjct: 754 QCQNGASCDHISGKCTCRTGFTGQHCEQRCA 784
Score = 73.3 bits (172), Expect = 4e-12
Identities = 59/204 (28%), Positives = 76/204 (37%), Gaps = 34/204 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
+C P +Y C C P G CLPG+ G C + C +
Sbjct: 608 ICPPGFYGHGCAQPC-PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQL 666
Query: 216 CH-PTHGRCDR-PGDCDCRPGWRGELCSQ-CQPY---PGCKHGY-------CNGSSWDCT 262
C +G C G C C PGW G+ CSQ C P P C H C+ C
Sbjct: 667 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726
Query: 263 CDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C W G+ C Q CG CQ+G +C++ + C C GF+G CE+
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK---CTCRTGFTGQHCEQ-- 781
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTC 340
CAP +G L TC
Sbjct: 782 -RCAPGTFGYGCQQLCECMNNSTC 804
>BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 153 bits (370), Expect = 4e-36
Identities = 154/526 (29%), Positives = 199/526 (37%), Gaps = 92/526 (17%)
Query: 198 CLPGW--QGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS----------QCQP 245
C PG+ GD C P+C E C HGRC P C C PGW G CS C
Sbjct: 88 CCPGYYENGDFCI-PLCTEEC--VHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
Query: 246 YPGCKHG-YCNGSSWDCTCDTNWGGILCDQDLNYCGTHE-----PCQ--HGGTCENTAPD 297
C++G CN + C C + G C ++L GTH PCQ HG +C+ A +
Sbjct: 145 RCQCQNGALCNPITGACVCAAGFRGWRC-EELCAPGTHGKGCQLPCQCRHGASCDPRAGE 203
Query: 298 QYFCRCAEGFSGVDCERVDNPCA-PQPC-AHGTCSLAGTTRGFT--CTCDRGWGGXXXXX 353
C CA G++GV CE + P + C C GT T C C GW G
Sbjct: 204 ---CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ 260
Query: 354 XXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGA 405
G PC HG C DH+ G C C G+ G C E+ S G ++
Sbjct: 261 PCPPGTFGQNCSQDCPCHHGGQC-DHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQRC 318
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAA 465
C N C+ T G +C C G+ G C+ + C + LHG C C C A
Sbjct: 319 --DCHNGGQCSPTTG--ACECEPGYKGPRCQERL--CP-EGLHGPGC-----TLPCPCDA 366
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
+C C +P +G C + CPVG+ G C+ C NG
Sbjct: 367 DNT-ISCHPVTGACTCQPGWSGHHCNE-------SCPVGYYGDGCQ------LPCTCQNG 412
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVRE 583
A C++ C CAPG+ G+ C A CS + C+ C NGGTC
Sbjct: 413 ADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSI------CS---CNNGGTCSPV 461
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGAL 643
+GS A G + P +C C G G
Sbjct: 462 DGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA---ACSPIDGSCSCTPGWLGDT 518
Query: 644 CEL-------SLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
CEL L+ C + C +G C C+AGWTG C
Sbjct: 519 CELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRC 562
Score = 143 bits (347), Expect = 2e-33
Identities = 167/585 (28%), Positives = 206/585 (35%), Gaps = 130/585 (22%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPD-GDKHCLPGWQGDNCEKPVCKEGCHPTH-- 220
LC P + C C+ R SC P G+ C PG+ G CE+ +C G H H
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGA----SCDPRAGECLCAPGYTGVYCEE-LCPPGSHGAHCE 229
Query: 221 --------GRCDR-PGDCDCRPGWRGELCSQCQPYPG-----------CKHG-YCNGSSW 259
G C G+C C PGW G +C+Q P PG C HG C+ +
Sbjct: 230 LRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP-PGTFGQNCSQDCPCHHGGQCDHVTG 288
Query: 260 DCTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC- 312
C C + G C ++ + C C +GG C +P C C G+ G C
Sbjct: 289 QCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQC---SPTTGACECEPGYKGPRCQ 345
Query: 313 -----ERVDNP-CA-PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
E + P C P PC A T S T CTC GW G G
Sbjct: 346 ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYYGDGC 403
Query: 363 -----CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACN 416
C +GA C G C CA G+ G CA S G GP C + +CN
Sbjct: 404 QLPCTCQNGADCHSITGG--CTCAPGFMGEVCAV--------SCAAGTYGPNCSSICSCN 453
Query: 417 NTAGGY------SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGR 470
N GG SC C GW G DC T C G ++ + C CA G A
Sbjct: 454 N--GGTCSPVDGSCTCKEGWQGLDC-------TLPCPSGTWGLNCNES--CTCANGAA-- 500
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
CS C+ P G C CP G G NC + HC C + C
Sbjct: 501 -CSPIDGSCSCTPGWLGDTC-------ELPCPDGTFGLNCSE---HC---DCSHADGCDP 546
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+C C GWTG C R CSV C+ C NGG+C E+GS
Sbjct: 547 VTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSV------SCS---CENGGSCSPEDGSCE 595
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP---PGWACGCREGRTGALCE 645
Q C+ S+ P C C G +GALC
Sbjct: 596 CAPGFRGPL----CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCN 651
Query: 646 -------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
D C N G C G C+C GW G+ C+
Sbjct: 652 QVCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCS 694
Score = 143 bits (346), Expect = 3e-33
Identities = 129/452 (28%), Positives = 174/452 (38%), Gaps = 88/452 (19%)
Query: 165 CQPNYYNTTCTTFCRPR-DDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKEG 215
C P YY FC P ++ H C HC PGW G +C P C
Sbjct: 88 CCPGYYENG--DFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 216 CHPTHGRCDRP--GDCDCRPGWRG----ELCSQ------CQPYPGCKHG-YCNGSSWDCT 262
C +G P G C C G+RG ELC+ CQ C+HG C+ + +C
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
Query: 263 CDTNWGGILCDQ------DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C + G+ C++ +C PCQ+GGTC + + C C G++G C +
Sbjct: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGE---CACPPGWTGAVCAQ-- 260
Query: 317 NPCAP----QPCAHG-TCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASG-------P 362
PC P Q C+ C G T C C G+ G + G
Sbjct: 261 -PCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCD 319
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNT 418
C +G C CEC G+ GP C E + C G PC N +C+
Sbjct: 320 CHNGGQCSPTTG--ACECEPGYKGPRCQERL--CPEGLHGPGCTLPCPCDADNTISCHPV 375
Query: 419 AGGYSCACLAGWTGRDCETNV------DDC--TGQCLHGATCIDLVDDFHCACAAGYAGR 470
G +C C GW+G C + D C C +GA C + C CA G+ G
Sbjct: 376 TG--ACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGE 431
Query: 471 TCSLDV------DDCAP-RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD------HC 517
C++ +C+ C NGG C + + C C G+ G +C +C
Sbjct: 432 VCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNC 489
Query: 518 AGS-PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
S C NGAAC + D C C PGW G C
Sbjct: 490 NESCTCANGAAC--SPIDGSCSCTPGWLGDTC 519
Score = 135 bits (326), Expect = 8e-31
Identities = 162/599 (27%), Positives = 208/599 (34%), Gaps = 111/599 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
LC P + C C ++ H+ G+ C PGW G C +P C +
Sbjct: 218 LCPPGSHGAHCELRCPCQNGGTCHHIT---GECACPPGWTGAVCAQPCPPGTFGQNCSQD 274
Query: 216 CHPTHG-RCDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
C HG +CD G C C G+ G+ C QC C +G C+ ++ C
Sbjct: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACE 334
Query: 263 CDTNWGGILCDQDLNYCGTHEP-CQHGGTCE--NTA---PDQYFCRCAEGFSGVDCERV- 315
C+ + G C + L G H P C C+ NT P C C G+SG C
Sbjct: 335 CEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESC 394
Query: 316 ------DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP------- 362
D P C +G T G CTC G+ G GP
Sbjct: 395 PVGYYGDGCQLPCTCQNGA-DCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICS 451
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAGG 421
C +G +C +DG +C C +GW G C + G + E C N AAC+ G
Sbjct: 452 CNNGGTCSP-VDG-SCTCKEGWQGLDCTLPCPSGTWGLNCNESCT--CANGAACSPIDG- 506
Query: 422 YSCACLAGWTGRDCETNVDDCTG--------QCLHGATCIDLVDDFHCACAAGYAGRTCS 473
SC+C GW G CE D T C H C + HC C AG+ G C
Sbjct: 507 -SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCD 563
Query: 474 LDVD------DCAPR-PCTNGGECVDLLNAYRC-----------ICPVGFSGTNCEDDRD 515
+C+ C NGG C + C ICP GF G C
Sbjct: 564 STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 623
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGM 573
C S C+ C C PG++G C Q A + C+ L C+
Sbjct: 624 LCVHS----SRPCHHISG--ICECLPGFSGALCNQVCAGGYFGQDCAQL------CS--- 668
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
CAN GTC +GS + G S AC
Sbjct: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA---SCSAEDGAC 725
Query: 634 GCREGRTGALCELSLDL------CGS-SPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C G TG C CG C+NG C SG C C G+TG+ C R
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQR 782
Score = 124 bits (300), Expect = 1e-27
Identities = 120/435 (27%), Positives = 162/435 (37%), Gaps = 92/435 (21%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKEG 215
C Y C++ C + +C+P DG C GWQG +C P C E
Sbjct: 437 CAAGTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNES 492
Query: 216 CHPTHGRCDRP--GDCDCRPGWRGELCS----------QCQPYPGCKHGY-CNGSSWDCT 262
C +G P G C C PGW G+ C C + C H C+ + C
Sbjct: 493 CTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 552
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C W GI CD T P + G C + C C G S C+P+
Sbjct: 553 CLAGWTGIRCDS------TCPPGRWGPNCSVS------CSCENGGS----------CSPE 590
Query: 323 PCAHGTCSLAGTTRGFTCT--CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCEC 380
G+C A RG C C G+ G C+H + H+ G CEC
Sbjct: 591 D---GSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL-----CVHSSRPCHHISGI-CEC 641
Query: 381 ADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETN 438
G++G C + C+G + L C N C+ G SC C GW G+DC
Sbjct: 642 LPGFSGALCNQ---VCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCSQA 696
Query: 439 VDD--CTGQCLHGATCID----LVDDFHCACAAGYAGRTCSLDVD------DCAPR-PCT 485
C H +C + +D C C G+ G C+ DC C
Sbjct: 697 CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ 756
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA----CYTAQS-DYY---C 537
NG C D ++ +C C GF+G +CE CA G G C + D+ C
Sbjct: 757 NGASC-DHISG-KCTCRTGFTGQHCEQ---RCAPGTFGYGCQQLCECMNNSTCDHVTGTC 811
Query: 538 HCAPGWTGKNCTQRA 552
+C+PG+ G C Q A
Sbjct: 812 YCSPGFKGIRCDQAA 826
Score = 120 bits (290), Expect = 2e-26
Identities = 132/451 (29%), Positives = 164/451 (36%), Gaps = 75/451 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--PV------CKE 214
LC + CT C P D SC P G C PGW G +C + PV C+
Sbjct: 348 LCPEGLHGPGCTLPC-PCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL 405
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDC 261
C +G C G C C PG+ GE+C+ C C +G C+ C
Sbjct: 406 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERV--D 316
TC W G+ C C TC N A P C C G+ G CE D
Sbjct: 466 TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPD 525
Query: 317 NPCAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-------CLHGA 367
H CS A T C C GW G GP C +G
Sbjct: 526 GTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYS 423
SC DG +CECA G+ GP C C G PC ++ C++ +G
Sbjct: 586 SCSPE-DG-SCECAPGFRGPLCQRI---CPPGFYGHGCAQPCPLCVHSSRPCHHISG--I 638
Query: 424 CACLAGWTGRDCETNV------DDCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C CL G++G C DC C + TC + D C C G+ G+ CS
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI--DGSCQCFPGWIGKDCSQA 696
Query: 476 VDDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA--GSPCGNGA 526
P C NG C A C C G++G C R A G CG
Sbjct: 697 CPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFCTQ-RCPAAFFGKDCGRVC 753
Query: 527 ACYTAQS-DYY---CHCAPGWTGKNCTQRAA 553
C S D+ C C G+TG++C QR A
Sbjct: 754 QCQNGASCDHISGKCTCRTGFTGQHCEQRCA 784
Score = 73.3 bits (172), Expect = 4e-12
Identities = 59/204 (28%), Positives = 76/204 (37%), Gaps = 34/204 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
+C P +Y C C P G CLPG+ G C + C +
Sbjct: 608 ICPPGFYGHGCAQPC-PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQL 666
Query: 216 CH-PTHGRCDR-PGDCDCRPGWRGELCSQ-CQPY---PGCKHGY-------CNGSSWDCT 262
C +G C G C C PGW G+ CSQ C P P C H C+ C
Sbjct: 667 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726
Query: 263 CDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C W G+ C Q CG CQ+G +C++ + C C GF+G CE+
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK---CTCRTGFTGQHCEQ-- 781
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTC 340
CAP +G L TC
Sbjct: 782 -RCAPGTFGYGCQQLCECMNNSTC 804
>BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein.
Length = 343
Score = 151 bits (367), Expect = 9e-36
Identities = 77/215 (35%), Positives = 101/215 (46%), Gaps = 16/215 (7%)
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTC 340
+EPC + G C +C+C EGF G C+ D PC C +G TC TC
Sbjct: 100 YEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATC 158
Query: 341 TCDRGWGGXXXXXXXXX--XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECS 397
C G+ G S PCL+G +C D + C C G+TG C + D C
Sbjct: 159 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACL 217
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDL 455
PC N + C A +SC CL G+TG+ CET+V++C G C HG TC++L
Sbjct: 218 SH--------PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 269
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
+ C C G+ G+ C CAP PC NGG C
Sbjct: 270 PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 304
Score = 133 bits (322), Expect = 3e-30
Identities = 78/243 (32%), Positives = 114/243 (46%), Gaps = 17/243 (6%)
Query: 322 QPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDGFTC 378
+PC + G C G+ C C G+ G + C +G +C + L TC
Sbjct: 101 EPCVNEGMCVTYHNGTGY-CKCPEGFLGEYCQHRDPCEKNR-CQNGGTCVAQAMLGKATC 158
Query: 379 ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCET 437
CA G+TG C S PC+N C+ + Y C C G+TG++C+
Sbjct: 159 RCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSRDTYECTCQVGFTGKECQW 212
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC-APRPCTNGGECVDLLN 495
D C C +G+TC + + F C C G+ G+ C DV++C P C +GG C++L
Sbjct: 213 T-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPG 271
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYYCHCAPGWTGKNCTQRAAR 554
+Y+C C GF+G C+ CA SPC NG C T + C+C P T + T+ R
Sbjct: 272 SYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPE-TVRRGTELWER 330
Query: 555 DRK 557
DR+
Sbjct: 331 DRE 333
Score = 111 bits (268), Expect = 9e-24
Identities = 64/188 (34%), Positives = 86/188 (45%), Gaps = 22/188 (11%)
Query: 408 PCVNAAACNNTAGGYS-CACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCAC 463
PCVN C G C C G+ G C+ D C +C +G TC+ ++ C C
Sbjct: 102 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRC 160
Query: 464 AAGYAGRTCSLDVDD-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGS 520
A+G+ G C C RPC NGG C L + Y C C VGF+G C+ D C
Sbjct: 161 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSH 219
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC NG+ C T + + C C G+TG+ C D C + G C +GGTC
Sbjct: 220 PCANGSTCTTVANQFSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGTC 266
Query: 581 VREEGSWR 588
+ GS++
Sbjct: 267 LNLPGSYQ 274
Score = 104 bits (250), Expect = 1e-21
Identities = 72/242 (29%), Positives = 98/242 (40%), Gaps = 28/242 (11%)
Query: 212 CKEGCHP--THGRC----DRPGDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW--- 259
C++G P G C + G C C G+ GE C P C++G C +
Sbjct: 96 CRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 155
Query: 260 -DCTCDTNWGGILCDQDLNY-CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
C C + + G C ++ C PC +GGTC + D Y C C GF+G +C+ D
Sbjct: 156 ATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD- 214
Query: 318 PCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDG 375
C PCA+G TC+ F+C C G+ G G C HG +C +
Sbjct: 215 ACLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGS 272
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRD 434
+ C+C G+TG C C A PCVN C T + C CL R
Sbjct: 273 YQCQCLQGFTGQYCDSLYVPC--------APSPCVNGGTCRQTGDFTFECNCLPETVRRG 324
Query: 435 CE 436
E
Sbjct: 325 TE 326
Score = 101 bits (242), Expect = 1e-20
Identities = 71/236 (30%), Positives = 94/236 (39%), Gaps = 28/236 (11%)
Query: 446 CLHGATCIDLVDDF-HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICP 502
C++ C+ + +C C G+ G C D C C NGG CV +L C C
Sbjct: 103 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCA 161
Query: 503 VGFSGTNCEDDRDH-CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTC 559
GF+G +C+ H C S PC NG C+ D Y C C G+TGK C
Sbjct: 162 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC----------- 210
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ ++ C CANG TC + ++ Q G
Sbjct: 211 ----QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHG 263
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
GTCL LP + C C +G TG C+ C SPC NGG C G + C C+
Sbjct: 264 GTCLN--LPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 317
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/204 (28%), Positives = 79/204 (38%), Gaps = 23/204 (11%)
Query: 483 PCTNGGECVDLLNAYR-CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHC 539
PC N G CV N C CP GF G C+ RD C + C NG C C C
Sbjct: 102 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRC 160
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXX 599
A G+TG++C + C V C NGGTC R
Sbjct: 161 ASGFTGEDCQYSTSHP---CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGF 205
Query: 600 XDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRN 658
G TC + + ++C C G TG CE ++ C C++
Sbjct: 206 TGKECQWTDACLSHPCAN-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQH 262
Query: 659 GGRCVGGSGWWMCECVAGWTGETC 682
GG C+ G + C+C+ G+TG+ C
Sbjct: 263 GGTCLNLPGSYQCQCLQGFTGQYC 286
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 102 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 146
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 147 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 205
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 206 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 252
>DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein.
Length = 315
Score = 151 bits (365), Expect = 2e-35
Identities = 69/188 (36%), Positives = 88/188 (46%), Gaps = 6/188 (3%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACAEDVDE 395
C+ V +
Sbjct: 204 TCSRPVQQ 211
Score = 120 bits (290), Expect = 2e-26
Identities = 67/188 (35%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGW 346
C C G+
Sbjct: 193 RCRCPAGF 200
Score = 116 bits (280), Expect = 3e-25
Identities = 62/178 (34%), Positives = 76/178 (42%), Gaps = 22/178 (12%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTC 205
Score = 112 bits (270), Expect = 5e-24
Identities = 60/184 (32%), Positives = 79/184 (42%), Gaps = 22/184 (11%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDCTGQ-CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGE 489
C+ +V C+ C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQ 550
C++
Sbjct: 204 TCSR 207
Score = 101 bits (241), Expect = 2e-20
Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 25/194 (12%)
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWG 347
G CE D CRC G+ G C++ C P C HG C G C C GW
Sbjct: 35 GFCE----DDNVCRCQPGWQGPLCDQ----CVTSPGCLHGLCGEPGQ-----CICTDGWD 81
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
G +S PC + +C DG + C CA G++G C + C + G+
Sbjct: 82 GELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC----VINGS- 136
Query: 407 GPCVNAAAC---NNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCA 462
PC + C A SC C G++G CE + CT C + C D+ DF C
Sbjct: 137 -PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCR 195
Query: 463 CAAGYAGRTCSLDV 476
C AG+ +TCS V
Sbjct: 196 CPAGFIDKTCSRPV 209
Score = 70.5 bits (165), Expect = 3e-11
Identities = 62/209 (29%), Positives = 79/209 (37%), Gaps = 30/209 (14%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
PC N G C G + C C AG+ +TC+
Sbjct: 178 PCENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 150 bits (363), Expect = 3e-35
Identities = 106/340 (31%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYC----GTHEPCQHGGTCENTAP 296
C P G C S+ C C W G LC D+N C GT CQ+GGTC NT
Sbjct: 7 CSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 65
Query: 297 DQYFCRCAEGFSGVDCERVDNPC---APQPCAHGTCS-----LAGTTRGFTCTCDRGWGG 348
Y C C G C + C + C HG C AG + ++C CD GW
Sbjct: 66 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK-YSCVCDAGWMS 124
Query: 349 XXXXXXXXXXAS------GPCLHGASCRDHLDGFTC-ECADGWTGPA-CAEDVDECSGRS 400
GPC C + F C C GW G ED++EC
Sbjct: 125 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE--- 181
Query: 401 MTEGALGPCVNAAACNNTAGGYSC-ACLAGWTG--RDCETNVDDCT---GQCLHGATCID 454
+ G C NT G C AC G+ G R C T D C+ G C A+C
Sbjct: 182 INNGGCS-VAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSS 239
Query: 455 LVDDFH-CACAAGYAGRT-----CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
+ C C GY G C + C PC NG +C+D ++ Y C C G++G
Sbjct: 240 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 298
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
NC ++ + C +PC NG C + C C WTG C
Sbjct: 299 NCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 338
Score = 150 bits (363), Expect = 3e-35
Identities = 104/350 (29%), Positives = 141/350 (40%), Gaps = 41/350 (11%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
+S PC +G +C + D F C C W GP C+ DV+EC + G C N C NT
Sbjct: 8 SSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECE---IYSGTPLSCQNGGTCVNT 64
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTG----QCLHGATCIDLVDD------FHCACAAGYA 468
G YSC C G C + DDC G +C+HG C DL+ + + C C AG+
Sbjct: 65 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 123
Query: 469 GR----TCSLDVDDCA--PRPCTNGGECVDLLNAYRC-ICPVGFSGTN--CEDDRD---H 516
C+LD D+C+ P PC+ +C + ++ C CP G+ G CED + +
Sbjct: 124 SSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 183
Query: 517 CAGSPCGNGAACYTAQSDYYCH-CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
G C +C C PG+ G R CSV + G C
Sbjct: 184 NGGCSVAPPVECVNTPGSSHCQACPPGYQGDG---RVCTLTDICSV--------SNGGCH 232
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGWACG 634
+C GS G C+ + G+ C
Sbjct: 233 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTV--SGYFCK 290
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C G TG C +++ C S+PC NGG CV G + CEC WTG C V
Sbjct: 291 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 340
Score = 131 bits (317), Expect = 1e-29
Identities = 108/344 (31%), Positives = 136/344 (39%), Gaps = 64/344 (18%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-----APQPCAHG-T 328
D C ++ PCQ+GG C N D +FC C + G C N C P C +G T
Sbjct: 3 DKKVCSSN-PCQNGGNCLNLH-DSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 60
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP---CLHGASCRDHL------DGFTCE 379
C T ++C C G G C+HG C D + ++C
Sbjct: 61 C--VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCV 117
Query: 380 CADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAGWTGRD 434
C GW PAC D DECS + GPC C NT G + C AC GW G
Sbjct: 118 CDAGWMSSPNSPACTLDRDECSFQP------GPCSTLVQCFNTQGSFYCGACPTGWQGNG 171
Query: 435 --CETNVDDC---TGQCLHG--ATCIDLVDDFHC-ACAAGYAG--RTCSL-DVDDCAPRP 483
CE ++++C G C C++ HC AC GY G R C+L D+ +
Sbjct: 172 YICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 230
Query: 484 CTNGGECVDLLNAYR-CICPVGFSGTN-----CEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C C L + C C G++G C + C PC NG C S Y+C
Sbjct: 231 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 289
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C GWTG NCT E C C NGGTCV
Sbjct: 290 KCDSGWTGVNCT--------------ENINECLSNPCLNGGTCV 319
Score = 120 bits (290), Expect = 2e-26
Identities = 106/372 (28%), Positives = 154/372 (41%), Gaps = 48/372 (12%)
Query: 208 EKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG----CKHG-YCN 255
+K VC G C D C C P W+G LCS +C+ Y G C++G C
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 62
Query: 256 GS--SWDCTCDTNWGGILCDQDLNYC--GTHEPCQHGGTCENTAPDQ-----YFCRCAEG 306
+ S+ C C G C + C G+ C HG CE+ +Q Y C C G
Sbjct: 63 NTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAG 121
Query: 307 F----SGVDCERVDNPCAPQPCAHGTCSLAGTTRG-FTC-TCDRGWGGXXXXXXXXXXA- 359
+ + C + C+ QP T T+G F C C GW G
Sbjct: 122 WMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 181
Query: 360 --SGPCLHG--ASCRDHLDGFTCE-CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+G C C + C+ C G+ G D C+ + + G C A+
Sbjct: 182 INNGGCSVAPPVECVNTPGSSHCQACPPGYQG-----DGRVCTLTDICSVSNGGCHPDAS 236
Query: 415 CNNTAGGYS-CACLAGWTGRD-----CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C++T G C CL G+TG C + C CL+G CID V + C C +G+
Sbjct: 237 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGW 295
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG-NGA 526
G C+ ++++C PC NGG CVD ++++ C C ++G C+ + C S G NG+
Sbjct: 296 TGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGS 355
Query: 527 ACYTAQSDYYCH 538
Y + Y H
Sbjct: 356 FSYRSPDVGYVH 367
Score = 98.7 bits (235), Expect = 9e-20
Identities = 81/307 (26%), Positives = 113/307 (36%), Gaps = 39/307 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC---TG---QCLHGATCIDLVDDFHC 461
PC N C N + C C W G C +V++C +G C +G TC++ + + C
Sbjct: 11 PCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 70
Query: 462 ACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNA------YRCICPVGF-SGTN-- 509
C G C+ DDC + C +G C DL+ Y C+C G+ S N
Sbjct: 71 HCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMSSPNSP 129
Query: 510 -CEDDRDHCA--GSPCGNGAACYTAQSDYYCHCAP-GWTGKNCTQRAARDRKTCSVLVEE 565
C DRD C+ PC C+ Q +YC P GW G D C +
Sbjct: 130 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI---CEDINECEI---N 183
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+ C+ A CV GS +C S
Sbjct: 184 NGGCS---VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC-SS 239
Query: 626 ALPPGWACGCREGRTGAL-----CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
L C C G TG C ++C S PC NG +C+ + C+C +GWTG
Sbjct: 240 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 298
Query: 681 TCAVRVS 687
C ++
Sbjct: 299 NCTENIN 305
Score = 94.7 bits (225), Expect = 1e-18
Identities = 94/363 (25%), Positives = 130/363 (35%), Gaps = 48/363 (13%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGP---CLHGASCRDHL 373
C+ PC +G L F C C W G SG C +G +C + +
Sbjct: 7 CSSNPCQNGGNCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM 65
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
++C C GP CA D+C G S+ G C + YSC C AGW
Sbjct: 66 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMSS 125
Query: 434 D----CETNVDDCT---GQCLHGATCIDLVDDFHC-ACAAGYAGR--TCSLDVDDCAPRP 483
C + D+C+ G C C + F+C AC G+ G C D+++C
Sbjct: 126 PNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICE-DINECE--- 181
Query: 484 CTNGG-------ECVDLLNAYRC-ICPVGFSGTN--CE-DDRDHCAGSPCGNGAACY-TA 531
NGG ECV+ + C CP G+ G C D + C A+C T
Sbjct: 182 INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTL 241
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
S C C PG+TG V+ S C C NG G +
Sbjct: 242 GSLPLCTCLPGYTGNGYGPNGC---------VQLSNICLSHPCLNGQCIDTVSGYFCKCD 292
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLC 651
++ GGTC+ ++C C TGALC++ +C
Sbjct: 293 SGWTGVNCTENINECLSNPCLN-----GGTCVDGV--DSFSCECTRLWTGALCQVPQQVC 345
Query: 652 GSS 654
G S
Sbjct: 346 GES 348
Score = 72.1 bits (169), Expect = 9e-12
Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC---AGSP--CGNGAA 527
++D C+ PC NGG C++L +++ CICP + G C D + C +G+P C NG
Sbjct: 1 TVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 60
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C Y CHC P G C + D + SV RC G+C
Sbjct: 61 CVNTMGSYSCHCPPETYGPQCASK-YDDCEGGSV-----ARCVHGIC 101
Score = 52.0 bits (119), Expect = 1e-05
Identities = 45/178 (25%), Positives = 57/178 (32%), Gaps = 22/178 (12%)
Query: 513 DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
D+ C+ +PC NG C ++C C P W G C+ D C + C
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSA----DVNECEIYSGTPLSCQ-- 56
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC----LPSALP 628
NGGTCV GS+ S G C A
Sbjct: 57 ---NGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH--GICEDLMREQAGE 111
Query: 629 PGWACGCREG----RTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMC-ECVAGWTG 679
P ++C C G C L D C PC +C G + C C GW G
Sbjct: 112 PKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG 169
Score = 39.9 bits (89), Expect = 0.044
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+C S+PC+NGG C+ + C C W G C+ V+
Sbjct: 6 VCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVN 43
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 150 bits (363), Expect = 3e-35
Identities = 106/340 (31%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYC----GTHEPCQHGGTCENTAP 296
C P G C S+ C C W G LC D+N C GT CQ+GGTC NT
Sbjct: 136 CSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 194
Query: 297 DQYFCRCAEGFSGVDCERVDNPC---APQPCAHGTCS-----LAGTTRGFTCTCDRGWGG 348
Y C C G C + C + C HG C AG + ++C CD GW
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK-YSCVCDAGWMS 253
Query: 349 XXXXXXXXXXAS------GPCLHGASCRDHLDGFTC-ECADGWTGPA-CAEDVDECSGRS 400
GPC C + F C C GW G ED++EC
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE--- 310
Query: 401 MTEGALGPCVNAAACNNTAGGYSC-ACLAGWTG--RDCETNVDDCT---GQCLHGATCID 454
+ G C NT G C AC G+ G R C T D C+ G C A+C
Sbjct: 311 INNGGCS-VAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSS 368
Query: 455 LVDDFH-CACAAGYAGRT-----CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
+ C C GY G C + C PC NG +C+D ++ Y C C G++G
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
NC ++ + C +PC NG C + C C WTG C
Sbjct: 428 NCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
Score = 150 bits (363), Expect = 3e-35
Identities = 104/350 (29%), Positives = 141/350 (40%), Gaps = 41/350 (11%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
+S PC +G +C + D F C C W GP C+ DV+EC + G C N C NT
Sbjct: 137 SSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECE---IYSGTPLSCQNGGTCVNT 193
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTG----QCLHGATCIDLVDD------FHCACAAGYA 468
G YSC C G C + DDC G +C+HG C DL+ + + C C AG+
Sbjct: 194 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 469 GR----TCSLDVDDCA--PRPCTNGGECVDLLNAYRC-ICPVGFSGTN--CEDDRD---H 516
C+LD D+C+ P PC+ +C + ++ C CP G+ G CED + +
Sbjct: 253 SSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 312
Query: 517 CAGSPCGNGAACYTAQSDYYCH-CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
G C +C C PG+ G R CSV + G C
Sbjct: 313 NGGCSVAPPVECVNTPGSSHCQACPPGYQGDG---RVCTLTDICSV--------SNGGCH 361
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGWACG 634
+C GS G C+ + G+ C
Sbjct: 362 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTV--SGYFCK 419
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C G TG C +++ C S+PC NGG CV G + CEC WTG C V
Sbjct: 420 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 131 bits (317), Expect = 1e-29
Identities = 108/344 (31%), Positives = 136/344 (39%), Gaps = 64/344 (18%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-----APQPCAHG-T 328
D C ++ PCQ+GG C N D +FC C + G C N C P C +G T
Sbjct: 132 DKKVCSSN-PCQNGGNCLNLH-DSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 189
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP---CLHGASCRDHL------DGFTCE 379
C T ++C C G G C+HG C D + ++C
Sbjct: 190 C--VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCV 246
Query: 380 CADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAGWTGRD 434
C GW PAC D DECS + GPC C NT G + C AC GW G
Sbjct: 247 CDAGWMSSPNSPACTLDRDECSFQP------GPCSTLVQCFNTQGSFYCGACPTGWQGNG 300
Query: 435 --CETNVDDC---TGQCLHG--ATCIDLVDDFHC-ACAAGYAG--RTCSL-DVDDCAPRP 483
CE ++++C G C C++ HC AC GY G R C+L D+ +
Sbjct: 301 YICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 484 CTNGGECVDLLNAYR-CICPVGFSGTN-----CEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C C L + C C G++G C + C PC NG C S Y+C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 418
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C GWTG NCT E C C NGGTCV
Sbjct: 419 KCDSGWTGVNCT--------------ENINECLSNPCLNGGTCV 448
Score = 120 bits (290), Expect = 2e-26
Identities = 106/372 (28%), Positives = 154/372 (41%), Gaps = 48/372 (12%)
Query: 208 EKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG----CKHG-YCN 255
+K VC G C D C C P W+G LCS +C+ Y G C++G C
Sbjct: 132 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 191
Query: 256 GS--SWDCTCDTNWGGILCDQDLNYC--GTHEPCQHGGTCENTAPDQ-----YFCRCAEG 306
+ S+ C C G C + C G+ C HG CE+ +Q Y C C G
Sbjct: 192 NTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAG 250
Query: 307 F----SGVDCERVDNPCAPQPCAHGTCSLAGTTRG-FTC-TCDRGWGGXXXXXXXXXXA- 359
+ + C + C+ QP T T+G F C C GW G
Sbjct: 251 WMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 360 --SGPCLHG--ASCRDHLDGFTCE-CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+G C C + C+ C G+ G D C+ + + G C A+
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQG-----DGRVCTLTDICSVSNGGCHPDAS 365
Query: 415 CNNTAGGYS-CACLAGWTGRD-----CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C++T G C CL G+TG C + C CL+G CID V + C C +G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGW 424
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG-NGA 526
G C+ ++++C PC NGG CVD ++++ C C ++G C+ + C S G NG+
Sbjct: 425 TGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGS 484
Query: 527 ACYTAQSDYYCH 538
Y + Y H
Sbjct: 485 FSYRSPDVGYVH 496
Score = 98.7 bits (235), Expect = 9e-20
Identities = 81/307 (26%), Positives = 113/307 (36%), Gaps = 39/307 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC---TG---QCLHGATCIDLVDDFHC 461
PC N C N + C C W G C +V++C +G C +G TC++ + + C
Sbjct: 140 PCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 462 ACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNA------YRCICPVGF-SGTN-- 509
C G C+ DDC + C +G C DL+ Y C+C G+ S N
Sbjct: 200 HCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMSSPNSP 258
Query: 510 -CEDDRDHCA--GSPCGNGAACYTAQSDYYCHCAP-GWTGKNCTQRAARDRKTCSVLVEE 565
C DRD C+ PC C+ Q +YC P GW G D C +
Sbjct: 259 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI---CEDINECEI---N 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+ C+ A CV GS +C S
Sbjct: 313 NGGCS---VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC-SS 368
Query: 626 ALPPGWACGCREGRTGAL-----CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
L C C G TG C ++C S PC NG +C+ + C+C +GWTG
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 681 TCAVRVS 687
C ++
Sbjct: 428 NCTENIN 434
Score = 95.1 bits (226), Expect = 1e-18
Identities = 98/376 (26%), Positives = 136/376 (36%), Gaps = 50/376 (13%)
Query: 307 FSGVDCERVDNP-CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGP- 362
F G+ + VD C+ PC +G L F C C W G SG
Sbjct: 124 FQGLQ-QTVDKKVCSSNPCQNGGNCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTP 181
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + + ++C C GP CA D+C G S+ G C +
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 421 GYSCACLAGWTGRD----CETNVDDCT---GQCLHGATCIDLVDDFHC-ACAAGYAGR-- 470
YSC C AGW C + D+C+ G C C + F+C AC G+ G
Sbjct: 242 KYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 471 TCSLDVDDCAPRPCTNGG-------ECVDLLNAYRC-ICPVGFSGTN--CE-DDRDHCAG 519
C D+++C NGG ECV+ + C CP G+ G C D +
Sbjct: 302 ICE-DINECE---INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSN 357
Query: 520 SPCGNGAACY-TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGG 578
C A+C T S C C PG+TG V+ S C C NG
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGC---------VQLSNICLSHPCLNGQ 408
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
G + ++ GGTC+ ++C C
Sbjct: 409 CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLN-----GGTCVDGV--DSFSCECTRL 461
Query: 639 RTGALCELSLDLCGSS 654
TGALC++ +CG S
Sbjct: 462 WTGALCQVPQQVCGES 477
Score = 53.6 bits (123), Expect = 3e-06
Identities = 47/186 (25%), Positives = 59/186 (31%), Gaps = 22/186 (11%)
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
F G D+ C+ +PC NG C ++C C P W G C+ D C +
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSA----DVNECEIYSG 179
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-- 622
C NGGTCV GS+ S G C
Sbjct: 180 TPLSCQ-----NGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH--GICED 232
Query: 623 --LPSALPPGWACGCREG----RTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMC-EC 673
A P ++C C G C L D C PC +C G + C C
Sbjct: 233 LMREQAGEPKYSCVCDAGWMSSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGAC 292
Query: 674 VAGWTG 679
GW G
Sbjct: 293 PTGWQG 298
Score = 39.9 bits (89), Expect = 0.044
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+C S+PC+NGG C+ + C C W G C+ V+
Sbjct: 135 VCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVN 172
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 149 bits (362), Expect = 4e-35
Identities = 106/340 (31%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYC----GTHEPCQHGGTCENTAP 296
C P G C S+ C C W G LC D+N C GT CQ+GGTC NT
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 194
Query: 297 DQYFCRCAEGFSGVDCERVDNPC---APQPCAHGTCS-----LAGTTRGFTCTCDRGW-- 346
Y C C G C + C + C HG C AG + ++C CD GW
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK-YSCVCDAGWMF 253
Query: 347 ----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTC-ECADGWTGPA-CAEDVDECSGRS 400
GPC C + F C C GW G ED++EC
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE--- 310
Query: 401 MTEGALGPCVNAAACNNTAGGYSC-ACLAGWTG--RDCETNVDDCT---GQCLHGATCID 454
+ G C NT G C AC G+ G R C T D C+ G C A+C
Sbjct: 311 INNGGCS-VAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSS 368
Query: 455 LVDDFH-CACAAGYAGRT-----CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
+ C C GY G C + C PC NG +C+D ++ Y C C G++G
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
NC ++ + C +PC NG C + C C WTG C
Sbjct: 428 NCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
Score = 149 bits (362), Expect = 4e-35
Identities = 104/350 (29%), Positives = 141/350 (40%), Gaps = 41/350 (11%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
+S PC +G +C + D F C C W GP C+ DV+EC + G C N C NT
Sbjct: 137 SSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECE---IYSGTPLSCQNGGTCVNT 193
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTG----QCLHGATCIDLVDD------FHCACAAGYA 468
G YSC C G C + DDC G +C+HG C DL+ + + C C AG+
Sbjct: 194 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 469 ----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRC-ICPVGFSGTN--CEDDRD---H 516
C+LD D+C+ P PC+ +C + ++ C CP G+ G CED + +
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 312
Query: 517 CAGSPCGNGAACYTAQSDYYCH-CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
G C +C C PG+ G R CSV + G C
Sbjct: 313 NGGCSVAPPVECVNTPGSSHCQACPPGYQGDG---RVCTLTDICSV--------SNGGCH 361
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGWACG 634
+C GS G C+ + G+ C
Sbjct: 362 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTV--SGYFCK 419
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C G TG C +++ C S+PC NGG CV G + CEC WTG C V
Sbjct: 420 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 133 bits (322), Expect = 3e-30
Identities = 109/344 (31%), Positives = 137/344 (39%), Gaps = 64/344 (18%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-----APQPCAHG-T 328
D C ++ PCQ+GGTC N D +FC C + G C N C P C +G T
Sbjct: 132 DKKVCSSN-PCQNGGTCLNLH-DSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 189
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP---CLHGASCRDHL------DGFTCE 379
C T ++C C G G C+HG C D + ++C
Sbjct: 190 C--VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCV 246
Query: 380 CADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAGWTGRD 434
C GW PAC D DECS + GPC C NT G + C AC GW G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQP------GPCSTLVQCFNTQGSFYCGACPTGWQGNG 300
Query: 435 --CETNVDDC---TGQCLHG--ATCIDLVDDFHC-ACAAGYAG--RTCSL-DVDDCAPRP 483
CE ++++C G C C++ HC AC GY G R C+L D+ +
Sbjct: 301 YICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 484 CTNGGECVDLLNAYR-CICPVGFSGTN-----CEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C C L + C C G++G C + C PC NG C S Y+C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 418
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C GWTG NCT E C C NGGTCV
Sbjct: 419 KCDSGWTGVNCT--------------ENINECLSNPCLNGGTCV 448
Score = 120 bits (289), Expect = 3e-26
Identities = 106/372 (28%), Positives = 154/372 (41%), Gaps = 48/372 (12%)
Query: 208 EKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG----CKHG-YCN 255
+K VC G C D C C P W+G LCS +C+ Y G C++G C
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 191
Query: 256 GS--SWDCTCDTNWGGILCDQDLNYC--GTHEPCQHGGTCENTAPDQ-----YFCRCAEG 306
+ S+ C C G C + C G+ C HG CE+ +Q Y C C G
Sbjct: 192 NTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAG 250
Query: 307 F----SGVDCERVDNPCAPQPCAHGTCSLAGTTRG-FTC-TCDRGWGGXXXXXXXXXXA- 359
+ + C + C+ QP T T+G F C C GW G
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 360 --SGPCLHG--ASCRDHLDGFTCE-CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+G C C + C+ C G+ G D C+ + + G C A+
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQG-----DGRVCTLTDICSVSNGGCHPDAS 365
Query: 415 CNNTAGGYS-CACLAGWTGRD-----CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C++T G C CL G+TG C + C CL+G CID V + C C +G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGW 424
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG-NGA 526
G C+ ++++C PC NGG CVD ++++ C C ++G C+ + C S G NG+
Sbjct: 425 TGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGS 484
Query: 527 ACYTAQSDYYCH 538
Y + Y H
Sbjct: 485 FSYRSPDVGYVH 496
Score = 99.1 bits (236), Expect = 7e-20
Identities = 81/307 (26%), Positives = 113/307 (36%), Gaps = 39/307 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC---TG---QCLHGATCIDLVDDFHC 461
PC N C N + C C W G C +V++C +G C +G TC++ + + C
Sbjct: 140 PCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 462 ACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNA------YRCICPVG--FSGTN- 509
C G C+ DDC + C +G C DL+ Y C+C G FS +
Sbjct: 200 HCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNSP 258
Query: 510 -CEDDRDHCA--GSPCGNGAACYTAQSDYYCHCAP-GWTGKNCTQRAARDRKTCSVLVEE 565
C DRD C+ PC C+ Q +YC P GW G D C +
Sbjct: 259 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI---CEDINECEI---N 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+ C+ A CV GS +C S
Sbjct: 313 NGGCS---VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC-SS 368
Query: 626 ALPPGWACGCREGRTGAL-----CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
L C C G TG C ++C S PC NG +C+ + C+C +GWTG
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 681 TCAVRVS 687
C ++
Sbjct: 428 NCTENIN 434
Score = 95.5 bits (227), Expect = 8e-19
Identities = 98/376 (26%), Positives = 136/376 (36%), Gaps = 50/376 (13%)
Query: 307 FSGVDCERVDNP-CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGP- 362
F G+ + VD C+ PC +G L F C C W G SG
Sbjct: 124 FQGLQ-QTVDKKVCSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTP 181
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + + ++C C GP CA D+C G S+ G C +
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 421 GYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHC-ACAAGYAGR-- 470
YSC C AGW C + D+C+ G C C + F+C AC G+ G
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 471 TCSLDVDDCAPRPCTNGG-------ECVDLLNAYRC-ICPVGFSGTN--CE-DDRDHCAG 519
C D+++C NGG ECV+ + C CP G+ G C D +
Sbjct: 302 ICE-DINECE---INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSN 357
Query: 520 SPCGNGAACY-TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGG 578
C A+C T S C C PG+TG V+ S C C NG
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGC---------VQLSNICLSHPCLNGQ 408
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
G + ++ GGTC+ ++C C
Sbjct: 409 CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLN-----GGTCVDGV--DSFSCECTRL 461
Query: 639 RTGALCELSLDLCGSS 654
TGALC++ +CG S
Sbjct: 462 WTGALCQVPQQVCGES 477
Score = 54.4 bits (125), Expect = 2e-06
Identities = 47/186 (25%), Positives = 59/186 (31%), Gaps = 22/186 (11%)
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
F G D+ C+ +PC NG C ++C C P W G C+ D C +
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSA----DVNECEIYSG 179
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-- 622
C NGGTCV GS+ S G C
Sbjct: 180 TPLSCQ-----NGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH--GICED 232
Query: 623 --LPSALPPGWACGCREG----RTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMC-EC 673
A P ++C C G C L D C PC +C G + C C
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGAC 292
Query: 674 VAGWTG 679
GW G
Sbjct: 293 PTGWQG 298
Score = 39.5 bits (88), Expect = 0.058
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+C S+PC+NGG C+ + C C W G C+ V+
Sbjct: 135 VCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVN 172
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 149 bits (362), Expect = 4e-35
Identities = 106/340 (31%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYC----GTHEPCQHGGTCENTAP 296
C P G C S+ C C W G LC D+N C GT CQ+GGTC NT
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 194
Query: 297 DQYFCRCAEGFSGVDCERVDNPC---APQPCAHGTCS-----LAGTTRGFTCTCDRGW-- 346
Y C C G C + C + C HG C AG + ++C CD GW
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK-YSCVCDAGWMF 253
Query: 347 ----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTC-ECADGWTGPA-CAEDVDECSGRS 400
GPC C + F C C GW G ED++EC
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE--- 310
Query: 401 MTEGALGPCVNAAACNNTAGGYSC-ACLAGWTG--RDCETNVDDCT---GQCLHGATCID 454
+ G C NT G C AC G+ G R C T D C+ G C A+C
Sbjct: 311 INNGGCS-VAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSS 368
Query: 455 LVDDFH-CACAAGYAGRT-----CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
+ C C GY G C + C PC NG +C+D ++ Y C C G++G
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
NC ++ + C +PC NG C + C C WTG C
Sbjct: 428 NCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
Score = 149 bits (362), Expect = 4e-35
Identities = 104/350 (29%), Positives = 141/350 (40%), Gaps = 41/350 (11%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
+S PC +G +C + D F C C W GP C+ DV+EC + G C N C NT
Sbjct: 137 SSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECE---IYSGTPLSCQNGGTCVNT 193
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTG----QCLHGATCIDLVDD------FHCACAAGYA 468
G YSC C G C + DDC G +C+HG C DL+ + + C C AG+
Sbjct: 194 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 469 ----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRC-ICPVGFSGTN--CEDDRD---H 516
C+LD D+C+ P PC+ +C + ++ C CP G+ G CED + +
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 312
Query: 517 CAGSPCGNGAACYTAQSDYYCH-CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
G C +C C PG+ G R CSV + G C
Sbjct: 313 NGGCSVAPPVECVNTPGSSHCQACPPGYQGDG---RVCTLTDICSV--------SNGGCH 361
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGWACG 634
+C GS G C+ + G+ C
Sbjct: 362 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTV--SGYFCK 419
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C G TG C +++ C S+PC NGG CV G + CEC WTG C V
Sbjct: 420 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 133 bits (322), Expect = 3e-30
Identities = 109/344 (31%), Positives = 137/344 (39%), Gaps = 64/344 (18%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-----APQPCAHG-T 328
D C ++ PCQ+GGTC N D +FC C + G C N C P C +G T
Sbjct: 132 DKKVCSSN-PCQNGGTCLNLH-DSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 189
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP---CLHGASCRDHL------DGFTCE 379
C T ++C C G G C+HG C D + ++C
Sbjct: 190 C--VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCV 246
Query: 380 CADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAGWTGRD 434
C GW PAC D DECS + GPC C NT G + C AC GW G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQP------GPCSTLVQCFNTQGSFYCGACPTGWQGNG 300
Query: 435 --CETNVDDC---TGQCLHG--ATCIDLVDDFHC-ACAAGYAG--RTCSL-DVDDCAPRP 483
CE ++++C G C C++ HC AC GY G R C+L D+ +
Sbjct: 301 YICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 484 CTNGGECVDLLNAYR-CICPVGFSGTN-----CEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C C L + C C G++G C + C PC NG C S Y+C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 418
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C GWTG NCT E C C NGGTCV
Sbjct: 419 KCDSGWTGVNCT--------------ENINECLSNPCLNGGTCV 448
Score = 120 bits (289), Expect = 3e-26
Identities = 106/372 (28%), Positives = 154/372 (41%), Gaps = 48/372 (12%)
Query: 208 EKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG----CKHG-YCN 255
+K VC G C D C C P W+G LCS +C+ Y G C++G C
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 191
Query: 256 GS--SWDCTCDTNWGGILCDQDLNYC--GTHEPCQHGGTCENTAPDQ-----YFCRCAEG 306
+ S+ C C G C + C G+ C HG CE+ +Q Y C C G
Sbjct: 192 NTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAG 250
Query: 307 F----SGVDCERVDNPCAPQPCAHGTCSLAGTTRG-FTC-TCDRGWGGXXXXXXXXXXA- 359
+ + C + C+ QP T T+G F C C GW G
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 360 --SGPCLHG--ASCRDHLDGFTCE-CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+G C C + C+ C G+ G D C+ + + G C A+
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQG-----DGRVCTLTDICSVSNGGCHPDAS 365
Query: 415 CNNTAGGYS-CACLAGWTGRD-----CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C++T G C CL G+TG C + C CL+G CID V + C C +G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGW 424
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG-NGA 526
G C+ ++++C PC NGG CVD ++++ C C ++G C+ + C S G NG+
Sbjct: 425 TGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGS 484
Query: 527 ACYTAQSDYYCH 538
Y + Y H
Sbjct: 485 FSYRSPDVGYVH 496
Score = 99.1 bits (236), Expect = 7e-20
Identities = 81/307 (26%), Positives = 113/307 (36%), Gaps = 39/307 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC---TG---QCLHGATCIDLVDDFHC 461
PC N C N + C C W G C +V++C +G C +G TC++ + + C
Sbjct: 140 PCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 462 ACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNA------YRCICPVG--FSGTN- 509
C G C+ DDC + C +G C DL+ Y C+C G FS +
Sbjct: 200 HCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNSP 258
Query: 510 -CEDDRDHCA--GSPCGNGAACYTAQSDYYCHCAP-GWTGKNCTQRAARDRKTCSVLVEE 565
C DRD C+ PC C+ Q +YC P GW G D C +
Sbjct: 259 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI---CEDINECEI---N 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+ C+ A CV GS +C S
Sbjct: 313 NGGCS---VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC-SS 368
Query: 626 ALPPGWACGCREGRTGAL-----CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
L C C G TG C ++C S PC NG +C+ + C+C +GWTG
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 681 TCAVRVS 687
C ++
Sbjct: 428 NCTENIN 434
Score = 95.5 bits (227), Expect = 8e-19
Identities = 98/376 (26%), Positives = 136/376 (36%), Gaps = 50/376 (13%)
Query: 307 FSGVDCERVDNP-CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGP- 362
F G+ + VD C+ PC +G L F C C W G SG
Sbjct: 124 FQGLQ-QTVDKKVCSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTP 181
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + + ++C C GP CA D+C G S+ G C +
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 421 GYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHC-ACAAGYAGR-- 470
YSC C AGW C + D+C+ G C C + F+C AC G+ G
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 471 TCSLDVDDCAPRPCTNGG-------ECVDLLNAYRC-ICPVGFSGTN--CE-DDRDHCAG 519
C D+++C NGG ECV+ + C CP G+ G C D +
Sbjct: 302 ICE-DINECE---INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSN 357
Query: 520 SPCGNGAACY-TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGG 578
C A+C T S C C PG+TG V+ S C C NG
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGC---------VQLSNICLSHPCLNGQ 408
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
G + ++ GGTC+ ++C C
Sbjct: 409 CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLN-----GGTCVDGV--DSFSCECTRL 461
Query: 639 RTGALCELSLDLCGSS 654
TGALC++ +CG S
Sbjct: 462 WTGALCQVPQQVCGES 477
Score = 54.4 bits (125), Expect = 2e-06
Identities = 47/186 (25%), Positives = 59/186 (31%), Gaps = 22/186 (11%)
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
F G D+ C+ +PC NG C ++C C P W G C+ D C +
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSA----DVNECEIYSG 179
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-- 622
C NGGTCV GS+ S G C
Sbjct: 180 TPLSCQ-----NGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH--GICED 232
Query: 623 --LPSALPPGWACGCREG----RTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMC-EC 673
A P ++C C G C L D C PC +C G + C C
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGAC 292
Query: 674 VAGWTG 679
GW G
Sbjct: 293 PTGWQG 298
Score = 39.5 bits (88), Expect = 0.058
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+C S+PC+NGG C+ + C C W G C+ V+
Sbjct: 135 VCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVN 172
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 149 bits (362), Expect = 4e-35
Identities = 106/340 (31%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYC----GTHEPCQHGGTCENTAP 296
C P G C S+ C C W G LC D+N C GT CQ+GGTC NT
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 194
Query: 297 DQYFCRCAEGFSGVDCERVDNPC---APQPCAHGTCS-----LAGTTRGFTCTCDRGW-- 346
Y C C G C + C + C HG C AG + ++C CD GW
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK-YSCVCDAGWMF 253
Query: 347 ----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTC-ECADGWTGPA-CAEDVDECSGRS 400
GPC C + F C C GW G ED++EC
Sbjct: 254 SPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE--- 310
Query: 401 MTEGALGPCVNAAACNNTAGGYSC-ACLAGWTG--RDCETNVDDCT---GQCLHGATCID 454
+ G C NT G C AC G+ G R C T D C+ G C A+C
Sbjct: 311 INNGGCS-VAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSS 368
Query: 455 LVDDFH-CACAAGYAGRT-----CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGT 508
+ C C GY G C + C PC NG +C+D ++ Y C C G++G
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
NC ++ + C +PC NG C + C C WTG C
Sbjct: 428 NCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
Score = 149 bits (362), Expect = 4e-35
Identities = 104/350 (29%), Positives = 141/350 (40%), Gaps = 41/350 (11%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
+S PC +G +C + D F C C W GP C+ DV+EC + G C N C NT
Sbjct: 137 SSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECE---IYSGTPLSCQNGGTCVNT 193
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTG----QCLHGATCIDLVDD------FHCACAAGYA 468
G YSC C G C + DDC G +C+HG C DL+ + + C C AG+
Sbjct: 194 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 469 ----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRC-ICPVGFSGTN--CEDDRD---H 516
C+LD D+C+ P PC+ +C + ++ C CP G+ G CED + +
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 312
Query: 517 CAGSPCGNGAACYTAQSDYYCH-CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
G C +C C PG+ G R CSV + G C
Sbjct: 313 NGGCSVAPPVECVNTPGSSHCQACPPGYQGDG---RVCTLTDICSV--------SNGGCH 361
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGWACG 634
+C GS G C+ + G+ C
Sbjct: 362 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTV--SGYFCK 419
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C G TG C +++ C S+PC NGG CV G + CEC WTG C V
Sbjct: 420 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 133 bits (322), Expect = 3e-30
Identities = 109/344 (31%), Positives = 137/344 (39%), Gaps = 64/344 (18%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPC-----APQPCAHG-T 328
D C ++ PCQ+GGTC N D +FC C + G C N C P C +G T
Sbjct: 132 DKKVCSSN-PCQNGGTCLNLH-DSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 189
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP---CLHGASCRDHL------DGFTCE 379
C T ++C C G G C+HG C D + ++C
Sbjct: 190 C--VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCV 246
Query: 380 CADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAGWTGRD 434
C GW PAC D DECS + GPC C NT G + C AC GW G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQP------GPCSTLVQCFNTQGSFYCGACPTGWQGNG 300
Query: 435 --CETNVDDC---TGQCLHG--ATCIDLVDDFHC-ACAAGYAG--RTCSL-DVDDCAPRP 483
CE ++++C G C C++ HC AC GY G R C+L D+ +
Sbjct: 301 YICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 484 CTNGGECVDLLNAYR-CICPVGFSGTN-----CEDDRDHCAGSPCGNGAACYTAQSDYYC 537
C C L + C C G++G C + C PC NG C S Y+C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 418
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
C GWTG NCT E C C NGGTCV
Sbjct: 419 KCDSGWTGVNCT--------------ENINECLSNPCLNGGTCV 448
Score = 120 bits (289), Expect = 3e-26
Identities = 106/372 (28%), Positives = 154/372 (41%), Gaps = 48/372 (12%)
Query: 208 EKPVCKEGCHPTHGRCDRPGD---CDCRPGWRGELCS----QCQPYPG----CKHG-YCN 255
+K VC G C D C C P W+G LCS +C+ Y G C++G C
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 191
Query: 256 GS--SWDCTCDTNWGGILCDQDLNYC--GTHEPCQHGGTCENTAPDQ-----YFCRCAEG 306
+ S+ C C G C + C G+ C HG CE+ +Q Y C C G
Sbjct: 192 NTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAG 250
Query: 307 F----SGVDCERVDNPCAPQPCAHGTCSLAGTTRG-FTC-TCDRGWGGXXXXXXXXXXA- 359
+ + C + C+ QP T T+G F C C GW G
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 360 --SGPCLHG--ASCRDHLDGFTCE-CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
+G C C + C+ C G+ G D C+ + + G C A+
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQG-----DGRVCTLTDICSVSNGGCHPDAS 365
Query: 415 CNNTAGGYS-CACLAGWTGRD-----CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGY 467
C++T G C CL G+TG C + C CL+G CID V + C C +G+
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGW 424
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCG-NGA 526
G C+ ++++C PC NGG CVD ++++ C C ++G C+ + C S G NG+
Sbjct: 425 TGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGS 484
Query: 527 ACYTAQSDYYCH 538
Y + Y H
Sbjct: 485 FSYRSPDVGYVH 496
Score = 99.1 bits (236), Expect = 7e-20
Identities = 81/307 (26%), Positives = 113/307 (36%), Gaps = 39/307 (12%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC---TG---QCLHGATCIDLVDDFHC 461
PC N C N + C C W G C +V++C +G C +G TC++ + + C
Sbjct: 140 PCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 462 ACAAGYAGRTCSLDVDDC---APRPCTNGGECVDLLNA------YRCICPVG--FSGTN- 509
C G C+ DDC + C +G C DL+ Y C+C G FS +
Sbjct: 200 HCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNSP 258
Query: 510 -CEDDRDHCA--GSPCGNGAACYTAQSDYYCHCAP-GWTGKNCTQRAARDRKTCSVLVEE 565
C DRD C+ PC C+ Q +YC P GW G D C +
Sbjct: 259 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI---CEDINECEI---N 312
Query: 566 SERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS 625
+ C+ A CV GS +C S
Sbjct: 313 NGGCS---VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC-SS 368
Query: 626 ALPPGWACGCREGRTGAL-----CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
L C C G TG C ++C S PC NG +C+ + C+C +GWTG
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGV 427
Query: 681 TCAVRVS 687
C ++
Sbjct: 428 NCTENIN 434
Score = 95.5 bits (227), Expect = 8e-19
Identities = 98/376 (26%), Positives = 136/376 (36%), Gaps = 50/376 (13%)
Query: 307 FSGVDCERVDNP-CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGP- 362
F G+ + VD C+ PC +G L F C C W G SG
Sbjct: 124 FQGLQ-QTVDKKVCSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTP 181
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + + ++C C GP CA D+C G S+ G C +
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 421 GYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHC-ACAAGYAGR-- 470
YSC C AGW C + D+C+ G C C + F+C AC G+ G
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 471 TCSLDVDDCAPRPCTNGG-------ECVDLLNAYRC-ICPVGFSGTN--CE-DDRDHCAG 519
C D+++C NGG ECV+ + C CP G+ G C D +
Sbjct: 302 ICE-DINECE---INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSN 357
Query: 520 SPCGNGAACY-TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGG 578
C A+C T S C C PG+TG V+ S C C NG
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGC---------VQLSNICLSHPCLNGQ 408
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
G + ++ GGTC+ ++C C
Sbjct: 409 CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLN-----GGTCVDGV--DSFSCECTRL 461
Query: 639 RTGALCELSLDLCGSS 654
TGALC++ +CG S
Sbjct: 462 WTGALCQVPQQVCGES 477
Score = 54.4 bits (125), Expect = 2e-06
Identities = 47/186 (25%), Positives = 59/186 (31%), Gaps = 22/186 (11%)
Query: 505 FSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
F G D+ C+ +PC NG C ++C C P W G C+ D C +
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSA----DVNECEIYSG 179
Query: 565 ESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC-- 622
C NGGTCV GS+ S G C
Sbjct: 180 TPLSCQ-----NGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH--GICED 232
Query: 623 --LPSALPPGWACGCREG----RTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMC-EC 673
A P ++C C G C L D C PC +C G + C C
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGAC 292
Query: 674 VAGWTG 679
GW G
Sbjct: 293 PTGWQG 298
Score = 39.5 bits (88), Expect = 0.058
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+C S+PC+NGG C+ + C C W G C+ V+
Sbjct: 135 VCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVN 172
>DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein.
Length = 212
Score = 149 bits (360), Expect = 6e-35
Identities = 68/183 (37%), Positives = 86/183 (46%), Gaps = 6/183 (3%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
C G +C C G+ G PC + C D F C C G+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 388 ACA 390
C+
Sbjct: 204 TCS 206
Score = 120 bits (290), Expect = 2e-26
Identities = 67/188 (35%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTCDRGW 346
C C G+
Sbjct: 193 RCRCPAGF 200
Score = 116 bits (280), Expect = 3e-25
Identities = 62/178 (34%), Positives = 76/178 (42%), Gaps = 22/178 (12%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
C C G++G C + + C P PC N G C D+ +RC CP GF C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTC 205
Score = 114 bits (275), Expect = 1e-24
Identities = 61/186 (32%), Positives = 80/186 (43%), Gaps = 22/186 (11%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDC-TGQCLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCA--PRPCTNGGE 489
C+ +V C + C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGK 546
CVD + C+CP GFSG CE + C +PC N C D+ C C G+ K
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 547 NCTQRA 552
C+ R+
Sbjct: 204 TCSSRS 209
Score = 71.7 bits (168), Expect = 1e-11
Identities = 63/211 (29%), Positives = 80/211 (37%), Gaps = 30/211 (14%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
PC N G C G + C C AG+ +TC+ R
Sbjct: 178 PCENDGVCTDIGGDFRCRCPAGFIDKTCSSR 208
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 146 bits (354), Expect = 3e-34
Identities = 71/202 (35%), Positives = 90/202 (44%), Gaps = 16/202 (7%)
Query: 317 NPCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCR---DH 372
N C PC + GTC+ + C C + G PC HG +C H
Sbjct: 345 NACLSSPCKNNGTCT-QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSH 403
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
DGF+C C G+ G C + D+C C N A C + Y C C +TG
Sbjct: 404 KDGFSCSCPLGFEGQRCEINPDDCEDND--------CENNATCVDGINNYVCICPPNYTG 455
Query: 433 RDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
C+ +D C + C H A CI L F C C GY+G+ C D DDC C +G +
Sbjct: 456 ELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQ 515
Query: 490 CVDLLNAYRCICPVGFSGTNCE 511
CVD +N Y C CP GFSG CE
Sbjct: 516 CVDTINGYTCTCPQGFSGPFCE 537
Score = 142 bits (343), Expect = 7e-33
Identities = 65/192 (33%), Positives = 96/192 (50%), Gaps = 9/192 (4%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTR-GFTCT 341
PC++ GTC + Y C C + G DC N C PC H GTC L+ + + GF+C+
Sbjct: 351 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 410
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
C G+ G C + A+C D ++ + C C +TG C E +D C
Sbjct: 411 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPE-- 468
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
L C + A C G+SC C+ G++G+ CET+ DDC +C HGA C+D ++ +
Sbjct: 469 ----LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 524
Query: 461 CACAAGYAGRTC 472
C C G++G C
Sbjct: 525 CTCPQGFSGPFC 536
Score = 130 bits (313), Expect = 3e-29
Identities = 61/193 (31%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 360 SGPCLHGASC-RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
S PC + +C +D ++ + C C + G C ++ C G G C ++
Sbjct: 349 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHG--GTC---HLSDSH 403
Query: 419 AGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
G+SC+C G+ G+ CE N DDC C + ATC+D ++++ C C Y G C +D
Sbjct: 404 KDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVID 463
Query: 478 DCAPRP--CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
C P C + +C+ L + C C G+SG CE D D C C +GA C + Y
Sbjct: 464 HCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 523
Query: 536 YCHCAPGWTGKNC 548
C C G++G C
Sbjct: 524 TCTCPQGFSGPFC 536
Score = 119 bits (286), Expect = 6e-26
Identities = 61/186 (32%), Positives = 86/186 (46%), Gaps = 14/186 (7%)
Query: 408 PCVNAAACN-NTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCI---DLVDDFHCA 462
PC N C + Y CAC + G+DC ++ C C HG TC D F C+
Sbjct: 351 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 410
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG--S 520
C G+ G+ C ++ DDC C N CVD +N Y CICP ++G C++ DHC +
Sbjct: 411 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELN 470
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC-SVLVEESERCAEGMCANGGT 579
C + A C + C C PG++GK C D C + +C + + NG T
Sbjct: 471 LCQHEAKCIPLDKGFSCECVPGYSGKLC----ETDNDDCVAHKCRHGAQCVDTI--NGYT 524
Query: 580 CVREEG 585
C +G
Sbjct: 525 CTCPQG 530
Score = 103 bits (247), Expect = 3e-21
Identities = 100/377 (26%), Positives = 145/377 (38%), Gaps = 39/377 (10%)
Query: 198 CLPGWQGDNCE--KPVCKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYPG 248
C G++G CE C++ + C D + C C P + GELC + C P
Sbjct: 411 CPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELN 470
Query: 249 -CKH-GYCN--GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C+H C + C C + G LC+ D + C H+ C+HG C +T + Y C C
Sbjct: 471 LCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHK-CRHGAQCVDTI-NGYTCTCP 528
Query: 305 EGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCL 364
+GFSG CE P P + + S TT T + G +
Sbjct: 529 QGFSGPFCEH------PPPMVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVD 582
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSG----RSMTEGALGP---CVNAAACNN 417
G L + A G P + +G R T+ LG C++ NN
Sbjct: 583 KGTP--KSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINN 640
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV- 476
+ A G CT C HG D C C G+ G C +
Sbjct: 641 ELQDFK-ALPPQSLG--VSPGCKSCT-VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR 696
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH---CAGSPCGNGAACYTAQS 533
D C C +G +CV +Y C C G+ G C++ D C+ C +G + Q
Sbjct: 697 DPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 755
Query: 534 DYYCHCAPGWTGKNCTQ 550
+ YC C PG++G++C Q
Sbjct: 756 EPYCLCQPGFSGEHCQQ 772
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 22/208 (10%)
Query: 479 CAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--- 534
C PC N G C D + YRC CP + G +C + C +PC +G C+ + S
Sbjct: 347 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 406
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
+ C C G+ G+ C + C + C N TCV ++
Sbjct: 407 FSCSCPLGFEGQRCEINP--------------DDCEDNDCENNATCVDGINNYVCICPPN 452
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
D +A C+P L G++C C G +G LCE D C +
Sbjct: 453 YTGELCDEVIDHCVPELNLCQHEA--KCIP--LDKGFSCECVPGYSGKLCETDNDDCVAH 508
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
CR+G +CV + C C G++G C
Sbjct: 509 KCRHGAQCVDTINGYTCTCPQGFSGPFC 536
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/126 (38%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 210 PVCKEGCHPTHGRCDRPGD----CDCRPGWRGELCSQ--CQPYPG--CKHGYC--NGSSW 259
P CK HG C C+CRPGW G LC Q P G C HG C G+S+
Sbjct: 657 PGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSY 716
Query: 260 DCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C C +GG LCD N C + C H G C + + +C C GFSG C++ +
Sbjct: 717 MCKCAEGYGGDLCDNKNDSANACSAFK-CHH-GQCHISDQGEPYCLCQPGFSGEHCQQ-E 773
Query: 317 NPCAPQ 322
NPC Q
Sbjct: 774 NPCLGQ 779
Score = 76.2 bits (179), Expect = 5e-13
Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 198 CLPGWQGDNCEKPV-------CKEG--CHPTHGRCDRPGDCDCRPGWRGELCS----QCQ 244
C ++G +C P+ C+ G CH + D C C G+ G+ C C+
Sbjct: 370 CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG-FSCSCPLGFEGQRCEINPDDCE 428
Query: 245 PYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYFC 301
+ C +G +++ C C N+ G LCD+ +++C CQH C + C
Sbjct: 429 DNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC-IPLDKGFSC 487
Query: 302 RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
C G+SG CE ++ C C HG T G+TCTC +G+ G
Sbjct: 488 ECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTINGYTCTCPQGFSG 533
Score = 65.7 bits (153), Expect = 8e-10
Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 424 CACLAGWTGRDCETNV-DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD---C 479
C C GWTG C+ D C G H C+ + C CA GY G C D C
Sbjct: 680 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 739
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC-------GNGAACYTAQ 532
+ C +G + C+C GFSG +C+ + + C G A+C TA
Sbjct: 740 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQVVREVIRRQKGYASCATAS 798
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRK---TC---SVLVEESERCAEGMC 574
C G + C ++ RK C S VEE ER E C
Sbjct: 799 KVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGC 846
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER-VDNPCAPQPCAHGTCSLAGTTRG 337
C + C+HG C + D C C G++G C++ +PC C HG C GT+
Sbjct: 659 CKSCTVCKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS-- 715
Query: 338 FTCTCDRGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFT-CECADGWTGPACAEDV 393
+ C C G+GG ++ C HG C G C C G++G C ++
Sbjct: 716 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE- 773
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE---TNVDDCTGQCLHGA 450
+ C G+ + E + A+C + C G + C+ + QC G+
Sbjct: 774 NPCLGQVVRE-VIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGS 832
Query: 451 TCIDLVD-DFHCACAA 465
+ ++ V+ C C A
Sbjct: 833 SFVEEVERHLECGCLA 848
Score = 48.4 bits (110), Expect = 1e-04
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 198 CLPGWQGDNCEK----PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC-------SQC 243
C PGW G C++ P CH HG+C G C C G+ G+LC + C
Sbjct: 682 CRPGWTGPLCDQEARDPCLGHRCH--HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 739
Query: 244 QPYPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
+ C HG C+ S C C + G C Q+ PC E + +
Sbjct: 740 SAFK-CHHGQCHISDQGEPYCLCQPGFSGEHCQQE-------NPCLGQVVREVIRRQKGY 791
Query: 301 CRCAEGFSGVDCERVDNPCAPQPC 324
CA S V C PQ C
Sbjct: 792 ASCATA-SKVPIMECRGGCGPQCC 814
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 633 CGCREGRTGALCELSL-DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C CR G TG LC+ D C C +G +CV +MC+C G+ G+ C
Sbjct: 680 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC 729
Score = 38.7 bits (86), Expect = 0.10
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC---VGGSGWWMCECVAG 676
GTC + + C C G C + ++ C +PC++GG C + C C G
Sbjct: 356 GTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLG 414
Query: 677 WTGETCAV 684
+ G+ C +
Sbjct: 415 FEGQRCEI 422
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCEL---SLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
G C+ A + C C EG G LC+ S + C + C +G + G C C G
Sbjct: 707 GKCV--ATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPG 764
Query: 677 WTGETC 682
++GE C
Sbjct: 765 FSGEHC 770
Score = 36.3 bits (80), Expect = 0.54
Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 8/58 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C +G + C C PGWTG C Q A R C RC G C GT
Sbjct: 665 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEA---RDPCL-----GHRCHHGKCVATGT 714
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 145 bits (352), Expect = 6e-34
Identities = 156/554 (28%), Positives = 206/554 (37%), Gaps = 105/554 (18%)
Query: 198 CLPGW--QGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS----------QCQP 245
C PG+ G+ C P C + C HGRC P C C PGW G CS C
Sbjct: 94 CCPGFYESGEMCV-PHCADKC--VHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS 150
Query: 246 YPGCKHG-YCNGSSWDCTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQ 298
CK+G CN + C C + G C+ N C CQ+G TC++ +
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE- 209
Query: 299 YFCRCAEGFSGVDCERVDNP--CAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXX 354
CRC G++G CE + P PQ C G T C+C GW G
Sbjct: 210 --CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP 267
Query: 355 XXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC--SGRSMTEGA 405
G C +G +C D G C C+ G+TG C DEC +
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTC-DAATG-QCHCSPGYTGERCQ---DECPVGTYGVLCAE 322
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV--DDCTG-QCLHGATC-IDLVDDFH- 460
CVN C + +G +C C AG+ G CE + + G +C C ++ H
Sbjct: 323 TCQCVNGGKCYHVSG--ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHP 380
Query: 461 ----CACAAGYAGRTCSLDVDDCAPR----------PCTNGGECVDLLNAYRCICPVGFS 506
CAC G++G C+ + C+P C NG +C + +C C GF
Sbjct: 381 MSGECACKPGWSGLYCN---ETCSPGFYGEACQQICSCQNGADCDSVTG--KCTCAPGFK 435
Query: 507 GTNCEDDRD------HCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
G +C +C+ C N A C + D C C GW G +C+ R T
Sbjct: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAVC--SPVDGSCTCKAGWHGVDCSIRCPSG--TW 491
Query: 560 SVLVEESERCAEGMCAN--GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQ 617
+ +C G N GTC G WR
Sbjct: 492 GFGCNLTCQCLNGGACNTLDGTCTCAPG-WR----GEKCELPCQDGTYGLNCAERCDCSH 546
Query: 618 AGGTCLPSA----LPPGWA---CG--CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGW 668
A G C P+ PGW+ C C EGR G C L C C+NG C G
Sbjct: 547 ADG-CHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLP---C---YCKNGASCSPDDG- 598
Query: 669 WMCECVAGWTGETC 682
+CEC G+ G TC
Sbjct: 599 -ICECAPGFRGTTC 611
Score = 144 bits (348), Expect = 2e-33
Identities = 153/592 (25%), Positives = 214/592 (36%), Gaps = 103/592 (17%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQG----DNCEKPV----CKEG 215
C +++ CT+ C+ ++ C P G HC G++G D CE+ C +
Sbjct: 139 CDGDHWGPHCTSRCQCKNGAL----CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQR 194
Query: 216 CHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
C +G CD G+C C PG+ G C QC+ C++G C+ + +C+
Sbjct: 195 CQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECS 254
Query: 263 CDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C + W G +C Q C C +GGTC+ A Q C C+ G++G C+ +
Sbjct: 255 CPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCD-AATGQ--CHCSPGYTGERCQD-E 310
Query: 317 NPCAPQP--CAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR 370
P CA TC + + C C+ G+ G C
Sbjct: 311 CPVGTYGVLCAE-TCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP 369
Query: 371 DHLDGF--------TCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAG 420
HL+ C C GW+G C E CS E + C N A C++ G
Sbjct: 370 CHLENTHSCHPMSGECACKPGWSGLYCNET---CSPGFYGEACQQICSCQNGADCDSVTG 426
Query: 421 GYSCACLAGWTGRDCETNVD------DCTGQC--LHGATCIDLVDDFHCACAAGYAGRTC 472
C C G+ G DC T +C+ +C + A C + D C C AG+ G C
Sbjct: 427 --KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPV--DGSCTCKAGWHGVDC 482
Query: 473 SLDVDD------C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHCAGSPCGN 524
S+ C C NGG C L C C G+ G CE +D G C
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAE 540
Query: 525 GAACYTAQSDY----YCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGG 578
C A + +C C PGW+G +C A R CS+ C C NG
Sbjct: 541 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSL------PC---YCKNGA 591
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
+C ++G Q + P G C C G
Sbjct: 592 SCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITG-LCDCLPG 650
Query: 639 RTGALC-------ELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
TGALC + G C N G C C+C GW G C+
Sbjct: 651 FTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR--SCQCYPGWIGSDCS 700
Score = 134 bits (324), Expect = 1e-30
Identities = 129/449 (28%), Positives = 162/449 (36%), Gaps = 81/449 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEGC 216
C P +Y C C ++ G + G C PG++G +C P C C
Sbjct: 400 CSPGFYGEACQQICSCQN---GADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 217 HPTHGRCDRP--GDCDCRPGWRGELCS-QCQPYP---GCK-------HGYCNGSSWDCTC 263
+ P G C C+ GW G CS +C GC G CN CTC
Sbjct: 457 GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTC 516
Query: 264 DTNWGGILCD---QDLNY---CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD- 316
W G C+ QD Y C C H C P CRC G+SGV C+ V
Sbjct: 517 APGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH---PTTGHCRCLPGWSGVHCDSVCA 573
Query: 317 ----NPCAPQPCA----------HGTCSLAGTTRGFTCT--CDRGWGGXXXXXXXXXXAS 360
P PC G C A RG TC C G+ G
Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQT-----C 628
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA-LGPCVNAAACNNTA 419
C+H + H+ G C+C G+TG C E SGR A + C N CN
Sbjct: 629 PQCVHSSGPCHHITGL-CDCLPGFTGALCNEVCP--SGRFGKNCAGICTCTNNGTCNPI- 684
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG--QCLHGATCID----LVDDFHCACAAGYAGRTCS 473
SC C GW G DC C+H C + D C C G+ G C+
Sbjct: 685 -DRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCT 743
Query: 474 LDVD------DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD-RDHCAGSPCGNG 525
DCA C NG +C D ++ +C C GF G +CE G C
Sbjct: 744 QRCPLGFYGKDCALICQCQNGADC-DHISG-QCTCRTGFMGRHCEQKCPSGTYGYGCRQI 801
Query: 526 AACYTAQS-DYY---CHCAPGWTGKNCTQ 550
C + D+ C+C+PGW G C Q
Sbjct: 802 CDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 122 bits (294), Expect = 6e-27
Identities = 133/454 (29%), Positives = 167/454 (36%), Gaps = 86/454 (18%)
Query: 165 CQPNYYNTTCTTFCR-PRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG-------- 215
C Y C C+ K H S G C G+ G+ CE +C EG
Sbjct: 311 CPVGTYGVLCAETCQCVNGGKCYHVS----GACLCEAGFAGERCEARLCPEGLYGIKCDK 366
Query: 216 ---CH--PTHGRCDRPGDCDCRPGWRGELCSQ----------CQPYPGCKHGY-CNGSSW 259
CH TH G+C C+PGW G C++ CQ C++G C+ +
Sbjct: 367 RCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG 426
Query: 260 DCTCDTNWGGILCDQDLNYCGTHE-PCQHGGTCENTA---PDQYFCRCAEGFSGVDCE-R 314
CTC + GI C GT+ C C+N A P C C G+ GVDC R
Sbjct: 427 KCTCAPGFKGIDCSTPCPL-GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR 485
Query: 315 VDNPCAPQPCAHGTCSL----AGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGASC 369
+ C + TC A T TCTC GW G G C C
Sbjct: 486 CPSGTWGFGC-NLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDC 544
Query: 370 RDHLDGFT-----CECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTAGGYS 423
H DG C C GW+G C E GR +L C N A+C+ G
Sbjct: 545 -SHADGCHPTTGHCRCLPGWSGVHCDSVCAE--GRWGPNCSLPCYCKNGASCSPDDGICE 601
Query: 424 CA-----------CLAGWTGRDCETNVDDC---TGQCLHGATCIDLVDDFHCA-----CA 464
CA C G+ G C C +G C H D + F A C
Sbjct: 602 CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCP 661
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--- 521
+G G+ C+ C CTN G C + + C C G+ G++C P
Sbjct: 662 SGRFGKNCA---GICT---CTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCI 713
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C NGA C + D C C PGWTG CTQR
Sbjct: 714 HTCNCHNGAFC--SAYDGECKCTPGWTGLYCTQR 745
Score = 116 bits (280), Expect = 3e-25
Identities = 129/451 (28%), Positives = 164/451 (36%), Gaps = 79/451 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKP--------VCKE 214
LC Y C C P + H SC P G+ C PGW G C + C++
Sbjct: 354 LCPEGLYGIKCDKRC-PCHLENTH-SCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQ 411
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKH-GYCNGSSWDC 261
C +G CD G C C PG++G CS C GCK+ C+ C
Sbjct: 412 ICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471
Query: 262 TCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
TC W G+ C C C +GG C NT C CA G+ G CE
Sbjct: 472 TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGAC-NTLDGT--CTCAPGWRGEKCEL- 527
Query: 316 DNPCAPQP----CAHGT-CSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP------ 362
PC CA CS A T C C GW G GP
Sbjct: 528 --PCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC 585
Query: 363 -CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA-CNNTAG 420
C +GASC DG CECA G+ G C CV+++ C++ G
Sbjct: 586 YCKNGASCSPD-DGI-CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITG 643
Query: 421 GYSCACLAGWTGRDCETNVD------DCTG--QCLHGATCIDLVDDFHCACAAGYAGRTC 472
C CL G+TG C +C G C + TC + D C C G+ G C
Sbjct: 644 --LCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPI--DRSCQCYPGWIGSDC 699
Query: 473 SLDVDDCAPRP-CTNGGECVD--LLNAY--RCICPVGFSGTNCED-------DRDHCAGS 520
S P C + C + +AY C C G++G C +D
Sbjct: 700 SQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALIC 759
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
C NGA C C C G+ G++C Q+
Sbjct: 760 QCQNGADCDHISGQ--CTCRTGFMGRHCEQK 788
Score = 75.4 bits (177), Expect = 1e-12
Identities = 78/273 (28%), Positives = 92/273 (33%), Gaps = 43/273 (15%)
Query: 436 ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD------CAPR-PCTNGG 488
E V C +C+HG CI C C G+ G CS D C R C NG
Sbjct: 103 EMCVPHCADKCVHGR-CIA---PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGA 158
Query: 489 ECVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
C + A C C GF G CED D C NGA C + C C P
Sbjct: 159 LCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPP 214
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG C + +RC C NGG C G
Sbjct: 215 GYTGAFCEDLCPPGKHGPQC----EQRCP---CQNGGVCHHVTGECSCPSGWMGTVCGQP 267
Query: 602 SXXXXXXXXXXXXXX-QAGGTCLPSALPPGWACGCREGRTGALCELSLD------LCGSS 654
GGTC + C C G TG C+ LC +
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTCDAAT----GQCHCSPGYTGERCQDECPVGTYGVLCAET 323
Query: 655 -PCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C NGG+C SG C C AG+ GE C R+
Sbjct: 324 CQCVNGGKCYHVSG--ACLCEAGFAGERCEARL 354
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/177 (27%), Positives = 72/177 (40%), Gaps = 31/177 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKE 214
+C + C C ++ +C P D C PGW G +C +P C
Sbjct: 659 VCPSGRFGKNCAGICTCTNNG----TCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIH 714
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCSQ----------CQPYPGCKHGY-CNGSSWDC 261
C+ +G C G+C C PGW G C+Q C C++G C+ S C
Sbjct: 715 TCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQC 774
Query: 262 TCDTNWGGILCDQDLNYCGTH-EPCQHGGTCENTAPDQYF---CRCAEGFSGVDCER 314
TC T + G C+Q GT+ C+ C N + + C C+ G+ G C++
Sbjct: 775 TCRTGFMGRHCEQKCP-SGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 144 bits (350), Expect = 1e-33
Identities = 98/305 (32%), Positives = 124/305 (40%), Gaps = 36/305 (11%)
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
YFC C GF G C+ NPC +PC +G +A + G+ C C G+ G
Sbjct: 6 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS-GYLCQCAPGYDGQNCSKELDAC 64
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC--VNAAACN 416
S PC + +C GF C C G+ G C DVDEC + PC AAC+
Sbjct: 65 QSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ--------PCHPTGTAACH 116
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDD---FHCACAAGYAGRTC 472
+ A + C CL G TG+ CE +D C Q C HG TC F C C G+ G TC
Sbjct: 117 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 176
Query: 473 SLDVDDCAPRPCTNGGECVDLLN---AYRCICPVGFSGTNC--EDDRDHCA-GSPC-GNG 525
S C C +GG C+ RC C G+ G +C C SPC NG
Sbjct: 177 SHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNG 236
Query: 526 AACYT---AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
+ T + C C G C + A K C R +G C G C
Sbjct: 237 SCSETTGLGGPGFRCSCPHSSPGPRCQKPGA---KGC------EGRSGDGACDAG--CSG 285
Query: 583 EEGSW 587
G+W
Sbjct: 286 PGGNW 290
Score = 144 bits (348), Expect = 2e-33
Identities = 98/324 (30%), Positives = 128/324 (39%), Gaps = 38/324 (11%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
+G S+ C C + G LC +N C + PCQ+G TC P Y C+CA G+ G +C +
Sbjct: 2 SGPSYFCHCPPGFQGSLCQDHVNPCES-RPCQNGATC-MAQPSGYLCQCAPGYDGQNCSK 59
Query: 315 VDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC--LHGASCRD 371
+ C QPC HGTC+ GF C C G+ G PC A+C
Sbjct: 60 ELDACQSQPCHNHGTCT--PKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHS 117
Query: 372 HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG---GYSCACLA 428
+ F C+C G TG C ++D C + PC + C TAG G+ C C
Sbjct: 118 LANAFYCQCLPGHTGQWCEVEIDPCHSQ--------PCFHGGTCEATAGSPLGFICHCPK 169
Query: 429 GWTGRDCETNVDDC-TGQCLHGATCIDLVDDF---HCACAAGYAGRTCSLD--VDDCA-P 481
G+ G C C C HG C+ CAC +GY G C C P
Sbjct: 170 GFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 229
Query: 482 RPCTNGGECVDLLN----AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
PC G C + +RC CP G C+ G+GA D C
Sbjct: 230 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC------DAGC 283
Query: 538 HCAPG--WTGKNCTQRAARDRKTC 559
PG W G +C+ K C
Sbjct: 284 -SGPGGNWDGGDCSLGVPDPWKGC 306
Score = 134 bits (325), Expect = 1e-30
Identities = 110/366 (30%), Positives = 153/366 (41%), Gaps = 46/366 (12%)
Query: 197 HCLPGWQGDNCEKPV--CKEGCHPTHGRC-DRPGD--CDCRPGWRGELCSQ----CQPYP 247
HC PG+QG C+ V C+ C +P C C PG+ G+ CS+ CQ P
Sbjct: 9 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 68
Query: 248 GCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--CENTAPDQYFCRC 303
HG C + C C + G+ C+ D++ C +PC GT C + A + ++C+C
Sbjct: 69 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLA-NAFYCQC 126
Query: 304 AEGFSGVDCERVDNPCAPQPCAH-GTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG 361
G +G CE +PC QPC H GTC + AG+ GF C C +G+ G
Sbjct: 127 LPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 186
Query: 362 PCLHGASC-RDHLDGF--TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C GF C C G+ GP C + + + G PC+ +C+ T
Sbjct: 187 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDC---LTPPAPKGC--GPPSPCLYNGSCSET 241
Query: 419 AG----GYSCACLAGWTGRDCE-TNVDDCTGQCLHGATCIDLVDDFHCACAAG-YAGRTC 472
G G+ C+C G C+ C G+ GA C D C+ G + G C
Sbjct: 242 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA-C-----DAGCSGPGGNWDGGDC 295
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
SL V D + C + C L +C C+ + G C AC T
Sbjct: 296 SLGVPD-PWKGCPSHSRCWLLFRDGQC-------HPQCDSEECLFDGYDCETPPAC-TPA 346
Query: 533 SDYYCH 538
D YCH
Sbjct: 347 YDQYCH 352
Score = 116 bits (280), Expect = 3e-25
Identities = 78/263 (29%), Positives = 107/263 (40%), Gaps = 27/263 (10%)
Query: 229 CDCRPGWRGELC----SQCQPYPGCKHG---YCNGSSWDCTCDTNWGGILCDQDLNYCGT 281
C C PG++G LC + C+ P C++G S + C C + G C ++L+ C +
Sbjct: 8 CHCPPGFQGSLCQDHVNPCESRP-CQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQS 66
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTC 340
+PC + GTC P + C C GF G+ CE + C QPC GT + F C
Sbjct: 67 -QPCHNHGTC-TPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYC 124
Query: 341 TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD---GFTCECADGWTGPACAEDVDECS 397
C G G S PC HG +C GF C C G+ GP C+ C
Sbjct: 125 QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCG 184
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET--NVDDC--TGQCLHGATCI 453
G L C+ + CACL+G+ G DC T C CL+ +C
Sbjct: 185 FHHCHHGGL--CLPSP---KPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCS 239
Query: 454 DLV----DDFHCACAAGYAGRTC 472
+ F C+C G C
Sbjct: 240 ETTGLGGPGFRCSCPHSSPGPRC 262
Score = 106 bits (255), Expect = 3e-22
Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
+Y C CP GF G+ C+D + C PC NGA C S Y C CAPG+ G+NC+
Sbjct: 5 SYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS------ 58
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
+E + C C N GTC + G + +
Sbjct: 59 --------KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG----DVDECLDQP 106
Query: 616 XQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSG---WWMCE 672
GT +L + C C G TG CE+ +D C S PC +GG C +G ++C
Sbjct: 107 CHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICH 166
Query: 673 CVAGWTGETCAVR 685
C G+ G TC+ R
Sbjct: 167 CPKGFEGPTCSHR 179
Score = 72.5 bits (170), Expect = 7e-12
Identities = 59/228 (25%), Positives = 80/228 (35%), Gaps = 20/228 (8%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
+ C C G+ G C V+ C RPC NG C+ + Y C C G+ G NC + D
Sbjct: 6 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELD--- 62
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGG 578
AC + + C P G +C C V+E C + C G
Sbjct: 63 --------ACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE---CLDQPCHPTG 111
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP-GWACGCRE 637
T S GGTC +A P G+ C C +
Sbjct: 112 TAACH--SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPK 169
Query: 638 GRTGALCELSLDLCGSSPCRNGGRCVGG--SGW-WMCECVAGWTGETC 682
G G C CG C +GG C+ G+ C C++G+ G C
Sbjct: 170 GFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 217
Score = 56.4 bits (130), Expect = 5e-07
Identities = 39/154 (25%), Positives = 52/154 (33%), Gaps = 22/154 (14%)
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXX 594
Y+CHC PG+ G C C C NG TC+ + +
Sbjct: 6 YFCHCPPGFQGSLCQDHV--------------NPCESRPCQNGATCMAQPSGYLCQCAPG 51
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSS 654
GTC P P G+ C C G G CE +D C
Sbjct: 52 YDGQNCSKELDACQSQPCHNH----GTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQ 105
Query: 655 PCRNGG--RCVGGSGWWMCECVAGWTGETCAVRV 686
PC G C + + C+C+ G TG+ C V +
Sbjct: 106 PCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI 139
Score = 56.0 bits (129), Expect = 6e-07
Identities = 19/55 (34%), Positives = 32/55 (58%)
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
P + C C G G+LC+ ++ C S PC+NG C+ ++C+C G+ G+ C+
Sbjct: 4 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS 58
>DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin
protein.
Length = 203
Score = 144 bits (350), Expect = 1e-33
Identities = 66/174 (37%), Positives = 83/174 (47%), Gaps = 6/174 (3%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGIL 271
C C+P +G C+ C C+PGW+G LC QC PGC HG C G C C W G L
Sbjct: 26 CFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLC-GEPGQCICTDGWDGEL 84
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GT 328
CD+D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GT
Sbjct: 85 CDRDVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 329 C-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECA 381
C G +C C G+ G PC + C D F C C+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCS 197
Score = 118 bits (285), Expect = 8e-26
Identities = 66/184 (35%), Positives = 82/184 (44%), Gaps = 20/184 (10%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C C P++ C D C PGWQG C++ V GC HG C PG C
Sbjct: 22 YGAECFPACNPQNG-----FCEDDNVCRCQPGWQGPLCDQCVTSPGC--LHGLCGEPGQC 74
Query: 230 DCRPGWRGELCSQ----CQPYPGCKHGYC---NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C GW GELC + C P +G C + ++C+C + G C + C +
Sbjct: 75 ICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVIN 134
Query: 283 -EPCQHGGTC--ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGF 338
PCQHGGTC + C C GFSG CE V N C P PC + G C+ G F
Sbjct: 135 GSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG--GDF 192
Query: 339 TCTC 342
C C
Sbjct: 193 RCRC 196
Score = 107 bits (256), Expect = 3e-22
Identities = 58/169 (34%), Positives = 72/169 (42%), Gaps = 22/169 (13%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C GW G S CLHG C + G C C DGW G C DV CS
Sbjct: 43 CRCQPGWQGPLCDQCVT---SPGCLHGL-CGE--PG-QCICTDGWDGELCDRDVRACSS- 94
Query: 400 SMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID- 454
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 95 -------APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 147
Query: 455 --LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C C G++G C + + C P PC N G C D+ +RC C
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196
Score = 105 bits (252), Expect = 8e-22
Identities = 57/174 (32%), Positives = 74/174 (42%), Gaps = 22/174 (12%)
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
D C C GW GP C D+C P C C C GW G
Sbjct: 39 DDNVCRCQPGWQGPLC----DQC--------VTSPGCLHGLCGEPG---QCICTDGWDGE 83
Query: 434 DCETNVDDC-TGQCLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCA--PRPCTNGGE 489
C+ +V C + C + TC+ L D + C+CA GY+G+ C C PC +GG
Sbjct: 84 LCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGT 143
Query: 490 CVD---LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
CVD + C+CP GFSG CE + C +PC N C D+ C C+
Sbjct: 144 CVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCS 197
Score = 89.4 bits (212), Expect = 6e-17
Identities = 56/183 (30%), Positives = 76/183 (41%), Gaps = 25/183 (13%)
Query: 289 GTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCTCDRGWG 347
G CE D CRC G+ G C++ C P C HG C G C C GW
Sbjct: 35 GFCE----DDNVCRCQPGWQGPLCDQ----CVTSPGCLHGLCGEPGQ-----CICTDGWD 81
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVDECSGRSMTEGAL 406
G +S PC + +C DG + C CA G++G C + C + G+
Sbjct: 82 GELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC----VINGS- 136
Query: 407 GPCVNAAAC---NNTAGGYSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCA 462
PC + C A SC C G++G CE + CT C + C D+ DF C
Sbjct: 137 -PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCR 195
Query: 463 CAA 465
C++
Sbjct: 196 CSS 198
Score = 61.3 bits (142), Expect = 2e-08
Identities = 58/199 (29%), Positives = 72/199 (36%), Gaps = 30/199 (15%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP-CGNGAACYTAQSDYY 536
+C P G C D N C C G+ G C D C SP C +G Q
Sbjct: 25 ECFPACNPQNGFCEDD-NV--CRCQPGWQGPLC----DQCVTSPGCLHGLCGEPGQ---- 73
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR-EEGSWRXXXXXXX 595
C C GW G+ C RD + CS CAN GTCV ++G +
Sbjct: 74 CICTDGWDGELCD----RDVRACS----------SAPCANNGTCVSLDDGLYECSCAPGY 119
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA-CGCREGRTGALCELSLDLCGSS 654
D Q GGTC+ A C C G +G CE+ + C +
Sbjct: 120 SGK--DCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPN 177
Query: 655 PCRNGGRCVGGSGWWMCEC 673
PC N G C G + C C
Sbjct: 178 PCENDGVCTDIGGDFRCRC 196
Score = 52.4 bits (120), Expect = 8e-06
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 629 PGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGWWMCECVAGWTGETC 682
PG C C +G G LC+ + C S+PC N G CV G + C C G++G+ C
Sbjct: 71 PG-QCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDC 124
>AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA1781)
protein.
Length = 969
Score = 144 bits (349), Expect = 1e-33
Identities = 147/511 (28%), Positives = 191/511 (37%), Gaps = 89/511 (17%)
Query: 211 VCKEGCHPTHGRCDRPGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSW 259
+C E C HGRC P C C PGW G CS C C++G CN +
Sbjct: 27 LCTEEC--VHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITG 84
Query: 260 DCTCDTNWGGILCDQDLNYCGTHE-----PCQ--HGGTCENTAPDQYFCRCAEGFSGVDC 312
C C + G C ++L GTH PCQ HG +C+ A + C CA G++GV C
Sbjct: 85 ACVCAAGFRGWRC-EELCAPGTHGKGCQLPCQCRHGASCDPRAGE---CLCAPGYTGVYC 140
Query: 313 ERVDNPCA-PQPC-AHGTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASG------- 361
E + P + C C GT T C C GW G G
Sbjct: 141 EELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC 200
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAG 420
PC HG C DH+ G C C G+ G C E+ S G ++ C N C+ T G
Sbjct: 201 PCHHGGQC-DHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQRC--DCHNGGQCSPTTG 256
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+C C G+ G C+ + C + LHG C C C A +C C
Sbjct: 257 --ACECEPGYKGPRCQERL--CP-EGLHGPGC-----TLPCPCDADNT-ISCHPVTGACT 305
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
+P +G C + CPVG+ G C+ C NGA C++ C CA
Sbjct: 306 CQPGWSGHHCNE-------SCPVGYYGDGCQ------LPCTCQNGADCHSITGG--CTCA 350
Query: 541 PGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXX 598
PG+ G+ C A CS + C+ C NGGTC +GS
Sbjct: 351 PGFMGEVCAVSCAAGTYGPNCSSI------CS---CNNGGTCSPVDGSCTCKEGWQGLDC 401
Query: 599 XXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCEL-------SLDLC 651
A G + P +C C G G CEL L+
Sbjct: 402 TLPCPSGTWGLNCNESCTCANGA---ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS 458
Query: 652 GSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C + C +G C C+AGWTG C
Sbjct: 459 EHCDCSHADGCDPVTG--HCCCLAGWTGIRC 487
Score = 143 bits (347), Expect = 2e-33
Identities = 167/585 (28%), Positives = 206/585 (35%), Gaps = 130/585 (22%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPD-GDKHCLPGWQGDNCEKPVCKEGCHPTH-- 220
LC P + C C+ R SC P G+ C PG+ G CE+ +C G H H
Sbjct: 100 LCAPGTHGKGCQLPCQCRHGA----SCDPRAGECLCAPGYTGVYCEE-LCPPGSHGAHCE 154
Query: 221 --------GRCDR-PGDCDCRPGWRGELCSQCQPYPG-----------CKHG-YCNGSSW 259
G C G+C C PGW G +C+Q P PG C HG C+ +
Sbjct: 155 LRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP-PGTFGQNCSQDCPCHHGGQCDHVTG 213
Query: 260 DCTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC- 312
C C + G C ++ + C C +GG C +P C C G+ G C
Sbjct: 214 QCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQC---SPTTGACECEPGYKGPRCQ 270
Query: 313 -----ERVDNP-CA-PQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-- 362
E + P C P PC A T S T CTC GW G G
Sbjct: 271 ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYYGDGC 328
Query: 363 -----CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACN 416
C +GA C G C CA G+ G CA S G GP C + +CN
Sbjct: 329 QLPCTCQNGADCHSITGG--CTCAPGFMGEVCAV--------SCAAGTYGPNCSSICSCN 378
Query: 417 NTAGGY------SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGR 470
N GG SC C GW G DC T C G ++ + C CA G A
Sbjct: 379 N--GGTCSPVDGSCTCKEGWQGLDC-------TLPCPSGTWGLNCNES--CTCANGAA-- 425
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
CS C+ P G C CP G G NC + HC C + C
Sbjct: 426 -CSPIDGSCSCTPGWLGDTC-------ELPCPDGTFGLNCSE---HC---DCSHADGCDP 471
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+C C GWTG C R CSV C+ C NGG+C E+GS
Sbjct: 472 VTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSV------SCS---CENGGSCSPEDGSCE 520
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALP---PGWACGCREGRTGALCE 645
Q C+ S+ P C C G +GALC
Sbjct: 521 CAPGFRGPL----CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCN 576
Query: 646 -------LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
D C N G C G C+C GW G+ C+
Sbjct: 577 QVCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCS 619
Score = 137 bits (332), Expect = 2e-31
Identities = 122/429 (28%), Positives = 165/429 (38%), Gaps = 85/429 (19%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGCHPTHGRCDRP--GDCDCRPGWR 236
H C HC PGW G +C P C C +G P G C C G+R
Sbjct: 34 HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR 93
Query: 237 G----ELCSQ------CQPYPGCKHG-YCNGSSWDCTCDTNWGGILCDQ------DLNYC 279
G ELC+ CQ C+HG C+ + +C C + G+ C++ +C
Sbjct: 94 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC 153
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP----QPCAHG-TCSLAGT 334
PCQ+GGTC + + C C G++G C + PC P Q C+ C G
Sbjct: 154 ELRCPCQNGGTCHHITGE---CACPPGWTGAVCAQ---PCPPGTFGQNCSQDCPCHHGGQ 207
Query: 335 TRGFT--CTCDRGWGGXXXXXXXXXXASG-------PCLHGASCRDHLDGFTCECADGWT 385
T C C G+ G + G C +G C CEC G+
Sbjct: 208 CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTG--ACECEPGYK 265
Query: 386 GPACAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYSCACLAGWTGRDCETNV-- 439
GP C E + C G PC N +C+ G +C C GW+G C +
Sbjct: 266 GPRCQERL--CPEGLHGPGCTLPCPCDADNTISCHPVTG--ACTCQPGWSGHHCNESCPV 321
Query: 440 ----DDC--TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV------DDCAP-RPCTN 486
D C C +GA C + C CA G+ G C++ +C+ C N
Sbjct: 322 GYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 379
Query: 487 GGECVDLLNAYRCICPVGFSGTNCEDDRD------HCAGS-PCGNGAACYTAQSDYYCHC 539
GG C + + C C G+ G +C +C S C NGAAC + D C C
Sbjct: 380 GGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC--SPIDGSCSC 435
Query: 540 APGWTGKNC 548
PGW G C
Sbjct: 436 TPGWLGDTC 444
Score = 135 bits (326), Expect = 8e-31
Identities = 162/599 (27%), Positives = 208/599 (34%), Gaps = 111/599 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
LC P + C C ++ H+ G+ C PGW G C +P C +
Sbjct: 143 LCPPGSHGAHCELRCPCQNGGTCHHIT---GECACPPGWTGAVCAQPCPPGTFGQNCSQD 199
Query: 216 CHPTHG-RCDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
C HG +CD G C C G+ G+ C QC C +G C+ ++ C
Sbjct: 200 CPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACE 259
Query: 263 CDTNWGGILCDQDLNYCGTHEP-CQHGGTCE--NTA---PDQYFCRCAEGFSGVDCERV- 315
C+ + G C + L G H P C C+ NT P C C G+SG C
Sbjct: 260 CEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESC 319
Query: 316 ------DNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP------- 362
D P C +G T G CTC G+ G GP
Sbjct: 320 PVGYYGDGCQLPCTCQNGA-DCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICS 376
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAGG 421
C +G +C +DG +C C +GW G C + G + E C N AAC+ G
Sbjct: 377 CNNGGTCSP-VDG-SCTCKEGWQGLDCTLPCPSGTWGLNCNESCT--CANGAACSPIDG- 431
Query: 422 YSCACLAGWTGRDCETNVDDCTG--------QCLHGATCIDLVDDFHCACAAGYAGRTCS 473
SC+C GW G CE D T C H C + HC C AG+ G C
Sbjct: 432 -SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCD 488
Query: 474 LDVD------DCAPR-PCTNGGECVDLLNAYRC-----------ICPVGFSGTNCEDDRD 515
+C+ C NGG C + C ICP GF G C
Sbjct: 489 STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 548
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLVEESERCAEGM 573
C S C+ C C PG++G C Q A + C+ L C+
Sbjct: 549 LCVHS----SRPCHHISG--ICECLPGFSGALCNQVCAGGYFGQDCAQL------CS--- 593
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
CAN GTC +GS + G S AC
Sbjct: 594 CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA---SCSAEDGAC 650
Query: 634 GCREGRTGALCELSLDL------CGS-SPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C G TG C CG C+NG C SG C C G+TG+ C R
Sbjct: 651 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQR 707
Score = 124 bits (300), Expect = 1e-27
Identities = 120/435 (27%), Positives = 162/435 (37%), Gaps = 92/435 (21%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKEG 215
C Y C++ C + +C+P DG C GWQG +C P C E
Sbjct: 362 CAAGTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNES 417
Query: 216 CHPTHGRCDRP--GDCDCRPGWRGELCS----------QCQPYPGCKHGY-CNGSSWDCT 262
C +G P G C C PGW G+ C C + C H C+ + C
Sbjct: 418 CTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 477
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQ 322
C W GI CD T P + G C + C C G S C+P+
Sbjct: 478 CLAGWTGIRCDS------TCPPGRWGPNCSVS------CSCENGGS----------CSPE 515
Query: 323 PCAHGTCSLAGTTRGFTCT--CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCEC 380
G+C A RG C C G+ G C+H + H+ G CEC
Sbjct: 516 D---GSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL-----CVHSSRPCHHISGI-CEC 566
Query: 381 ADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETN 438
G++G C + C+G + L C N C+ G SC C GW G+DC
Sbjct: 567 LPGFSGALCNQ---VCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFPGWIGKDCSQA 621
Query: 439 VDD--CTGQCLHGATCID----LVDDFHCACAAGYAGRTCSLDVD------DCAPR-PCT 485
C H +C + +D C C G+ G C+ DC C
Sbjct: 622 CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ 681
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA----CYTAQS-DYY---C 537
NG C D ++ +C C GF+G +CE CA G G C + D+ C
Sbjct: 682 NGASC-DHISG-KCTCRTGFTGQHCEQ---RCAPGTFGYGCQQLCECMNNSTCDHVTGTC 736
Query: 538 HCAPGWTGKNCTQRA 552
+C+PG+ G C Q A
Sbjct: 737 YCSPGFKGIRCDQAA 751
Score = 120 bits (290), Expect = 2e-26
Identities = 132/451 (29%), Positives = 164/451 (36%), Gaps = 75/451 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--PV------CKE 214
LC + CT C P D SC P G C PGW G +C + PV C+
Sbjct: 273 LCPEGLHGPGCTLPC-PCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL 330
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDC 261
C +G C G C C PG+ GE+C+ C C +G C+ C
Sbjct: 331 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 390
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERV--D 316
TC W G+ C C TC N A P C C G+ G CE D
Sbjct: 391 TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPD 450
Query: 317 NPCAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-------CLHGA 367
H CS A T C C GW G GP C +G
Sbjct: 451 GTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 510
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYS 423
SC DG +CECA G+ GP C C G PC ++ C++ +G
Sbjct: 511 SCSPE-DG-SCECAPGFRGPLCQRI---CPPGFYGHGCAQPCPLCVHSSRPCHHISG--I 563
Query: 424 CACLAGWTGRDCETNV------DDCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C CL G++G C DC C + TC + D C C G+ G+ CS
Sbjct: 564 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI--DGSCQCFPGWIGKDCSQA 621
Query: 476 VDDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA--GSPCGNGA 526
P C NG C A C C G++G C R A G CG
Sbjct: 622 CPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFCTQ-RCPAAFFGKDCGRVC 678
Query: 527 ACYTAQS-DYY---CHCAPGWTGKNCTQRAA 553
C S D+ C C G+TG++C QR A
Sbjct: 679 QCQNGASCDHISGKCTCRTGFTGQHCEQRCA 709
Score = 73.3 bits (172), Expect = 4e-12
Identities = 59/204 (28%), Positives = 76/204 (37%), Gaps = 34/204 (16%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEG 215
+C P +Y C C P G CLPG+ G C + C +
Sbjct: 533 ICPPGFYGHGCAQPC-PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQL 591
Query: 216 CH-PTHGRCDR-PGDCDCRPGWRGELCSQ-CQPY---PGCKHGY-------CNGSSWDCT 262
C +G C G C C PGW G+ CSQ C P P C H C+ C
Sbjct: 592 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 651
Query: 263 CDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C W G+ C Q CG CQ+G +C++ + C C GF+G CE+
Sbjct: 652 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK---CTCRTGFTGQHCEQ-- 706
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTC 340
CAP +G L TC
Sbjct: 707 -RCAPGTFGYGCQQLCECMNNSTC 729
>X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor
protein.
Length = 750
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 207 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 264
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 265 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYTGED----- 308
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 309 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 358
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 359 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 402
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 403 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 452
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 453 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 499
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 500 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 557
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 558 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 610
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 611 WEGYVSEDCSIR 622
Score = 134 bits (323), Expect = 2e-30
Identities = 148/531 (27%), Positives = 183/531 (34%), Gaps = 93/531 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 299 VCNPGYTGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 355
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 356 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 408
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 409 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 454
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 455 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 507
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 508 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 545
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 546 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 590
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 591 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 644
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 645 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 704
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C EG G C ++ C CR G C GS C C G+ GE C
Sbjct: 705 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDC 748
Score = 126 bits (303), Expect = 5e-28
Identities = 133/474 (28%), Positives = 157/474 (33%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 159 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 216
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 217 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 261
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+TG +
Sbjct: 262 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYTG-------E 307
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 308 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 356
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 357 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 404
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 405 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 453
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 454 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 513
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 514 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 560
Score = 99.1 bits (236), Expect = 7e-20
Identities = 102/372 (27%), Positives = 129/372 (34%), Gaps = 65/372 (17%)
Query: 329 CSLAGT--TRGFTCTCDRGWGGXXXXXXXXX--------XASGPCLHGASCRDHLDGFTC 378
CSL G TC+C+ GWGG ASG C + + C
Sbjct: 146 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 205
Query: 379 ECADGWTGPACA--EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C G+TGP+C +C GR G CV C C AG++G DC
Sbjct: 206 VCFPGYTGPSCGWPSCPGDCQGR-------GRCVQGV----------CVCRAGFSGPDCS 248
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C C C + C C GY G C + C PR C+ G C +
Sbjct: 249 QR--SCPRGCSQRGRC----EGGRCVCDPGYTGDDCGMR--SC-PRGCSQRGRCEN---- 295
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
RC+C G++G ED C C G + D C C PG+TG++C R
Sbjct: 296 GRCVCNPGYTG---ED----CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----- 343
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRX---XXXXXXXXXXXDSXXXXXXXXXXX 613
+C E RC +G C E+ S R +
Sbjct: 344 -SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC 402
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C G TG C C CR GRC G +C C
Sbjct: 403 GVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSRAC-PRDCRGRGRCENG----VCVC 455
Query: 674 VAGWTGETCAVR 685
AG++GE C VR
Sbjct: 456 NAGYSGEDCGVR 467
Score = 74.9 bits (176), Expect = 1e-12
Identities = 64/228 (28%), Positives = 83/228 (36%), Gaps = 24/228 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 547 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 603
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 604 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 658
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 659 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 709
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE 391
G+ G G C C D +C C DG+ G C E
Sbjct: 710 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGE 750
>U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein.
Length = 4289
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYTGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (323), Expect = 2e-30
Identities = 148/531 (27%), Positives = 183/531 (34%), Gaps = 93/531 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYTGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C EG G C ++ C CR G C GS C C G+ GE C
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDC 745
Score = 126 bits (303), Expect = 5e-28
Identities = 133/474 (28%), Positives = 157/474 (33%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+TG +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYTG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 99.1 bits (236), Expect = 7e-20
Identities = 102/372 (27%), Positives = 129/372 (34%), Gaps = 65/372 (17%)
Query: 329 CSLAGT--TRGFTCTCDRGWGGXXXXXXXXX--------XASGPCLHGASCRDHLDGFTC 378
CSL G TC+C+ GWGG ASG C + + C
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 379 ECADGWTGPACA--EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C G+TGP+C +C GR G CV C C AG++G DC
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGR-------GRCVQGV----------CVCRAGFSGPDCS 245
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C C C + C C GY G C + C PR C+ G C +
Sbjct: 246 QR--SCPRGCSQRGRC----EGGRCVCDPGYTGDDCGMR--SC-PRGCSQRGRCEN---- 292
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
RC+C G++G ED C C G + D C C PG+TG++C R
Sbjct: 293 GRCVCNPGYTG---ED----CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----- 340
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRX---XXXXXXXXXXXDSXXXXXXXXXXX 613
+C E RC +G C E+ S R +
Sbjct: 341 -SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC 399
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C G TG C C CR GRC G +C C
Sbjct: 400 GVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSRAC-PRDCRGRGRCENG----VCVC 452
Query: 674 VAGWTGETCAVR 685
AG++GE C VR
Sbjct: 453 NAGYSGEDCGVR 464
Score = 76.2 bits (179), Expect = 5e-13
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 24/245 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G+ G G C C D +C C DG+ G C E S + +
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEARVPSSASAYDQ 759
Query: 404 GALGP 408
L P
Sbjct: 760 RGLAP 764
>BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein
protein.
Length = 236
Score = 143 bits (346), Expect = 3e-33
Identities = 72/197 (36%), Positives = 94/197 (47%), Gaps = 16/197 (8%)
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX- 357
+C+C EGF G C+ D PC C +G TC TC C G+ G
Sbjct: 11 YCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 358 -XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
S PCL+G +C D + C C G+TG C + D C PC N + C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH--------PCANGSTC 120
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
A +SC CL G+TG+ CET+V++C G C HG TC++L + C C G+ G+ C
Sbjct: 121 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 474 LDVDDCAPRPCTNGGEC 490
CAP PC NGG C
Sbjct: 181 SLYVPCAPSPCVNGGTC 197
Score = 130 bits (313), Expect = 3e-29
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAPGWTGKNCTQRAARDRK 557
C+C P T + T+ RDR+
Sbjct: 207 CNCLPE-TVRRGTELWERDRE 226
Score = 105 bits (251), Expect = 1e-21
Identities = 60/174 (34%), Positives = 82/174 (47%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GGTC+ GS++
Sbjct: 127 FSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGTCLNLPGSYQ 167
Score = 102 bits (244), Expect = 7e-21
Identities = 67/221 (30%), Positives = 90/221 (40%), Gaps = 22/221 (9%)
Query: 227 GDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG +C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRDCE 436
A PCVN C T + C CL R E
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPETVRRGTE 219
Score = 100 bits (240), Expect = 2e-20
Identities = 69/221 (31%), Positives = 88/221 (39%), Gaps = 27/221 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GGTCL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGTCLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 143 bits (346), Expect = 3e-33
Identities = 72/197 (36%), Positives = 94/197 (47%), Gaps = 16/197 (8%)
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX- 357
+C+C EGF G C+ D PC C +G TC TC C G+ G
Sbjct: 11 YCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 358 -XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
S PCL+G +C D + C C G+TG C + D C PC N + C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH--------PCANGSTC 120
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
A +SC CL G+TG+ CET+V++C G C HG TC++L + C C G+ G+ C
Sbjct: 121 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 474 LDVDDCAPRPCTNGGEC 490
CAP PC NGG C
Sbjct: 181 SLYVPCAPSPCVNGGTC 197
Score = 130 bits (313), Expect = 3e-29
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAPGWTGKNCTQRAARDRK 557
C+C P T + T+ RDR+
Sbjct: 207 CNCLPE-TVRRGTELWERDRE 226
Score = 105 bits (251), Expect = 1e-21
Identities = 60/174 (34%), Positives = 82/174 (47%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GGTC+ GS++
Sbjct: 127 FSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGTCLNLPGSYQ 167
Score = 102 bits (244), Expect = 7e-21
Identities = 67/221 (30%), Positives = 90/221 (40%), Gaps = 22/221 (9%)
Query: 227 GDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG +C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRDCE 436
A PCVN C T + C CL R E
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPETVRRGTE 219
Score = 100 bits (240), Expect = 2e-20
Identities = 69/221 (31%), Positives = 88/221 (39%), Gaps = 27/221 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GGTCL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGTCLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYTGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (325), Expect = 1e-30
Identities = 149/535 (27%), Positives = 184/535 (34%), Gaps = 93/535 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYTGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C EG G C ++ C CR G C GS C C G+ GE C V
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 126 bits (303), Expect = 5e-28
Identities = 133/474 (28%), Positives = 157/474 (33%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+TG +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYTG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 99.1 bits (236), Expect = 7e-20
Identities = 102/372 (27%), Positives = 129/372 (34%), Gaps = 65/372 (17%)
Query: 329 CSLAGT--TRGFTCTCDRGWGGXXXXXXXXX--------XASGPCLHGASCRDHLDGFTC 378
CSL G TC+C+ GWGG ASG C + + C
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 379 ECADGWTGPACA--EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C G+TGP+C +C GR G CV C C AG++G DC
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGR-------GRCVQGV----------CVCRAGFSGPDCS 245
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C C C + C C GY G C + C PR C+ G C +
Sbjct: 246 QR--SCPRGCSQRGRC----EGGRCVCDPGYTGDDCGMR--SC-PRGCSQRGRCEN---- 292
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
RC+C G++G ED C C G + D C C PG+TG++C R
Sbjct: 293 GRCVCNPGYTG---ED----CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----- 340
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRX---XXXXXXXXXXXDSXXXXXXXXXXX 613
+C E RC +G C E+ S R +
Sbjct: 341 -SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC 399
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C G TG C C CR GRC G +C C
Sbjct: 400 GVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSRAC-PRDCRGRGRCENG----VCVC 452
Query: 674 VAGWTGETCAVR 685
AG++GE C VR
Sbjct: 453 NAGYSGEDCGVR 464
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
G+ G G C C D +C C DG+ G C E+V G M
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRM 757
>AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYTGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (325), Expect = 1e-30
Identities = 149/535 (27%), Positives = 184/535 (34%), Gaps = 93/535 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYTGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C EG G C ++ C CR G C GS C C G+ GE C V
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 126 bits (303), Expect = 5e-28
Identities = 133/474 (28%), Positives = 157/474 (33%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+TG +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYTG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 99.1 bits (236), Expect = 7e-20
Identities = 102/372 (27%), Positives = 129/372 (34%), Gaps = 65/372 (17%)
Query: 329 CSLAGT--TRGFTCTCDRGWGGXXXXXXXXX--------XASGPCLHGASCRDHLDGFTC 378
CSL G TC+C+ GWGG ASG C + + C
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 379 ECADGWTGPACA--EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C G+TGP+C +C GR G CV C C AG++G DC
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGR-------GRCVQGV----------CVCRAGFSGPDCS 245
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C C C + C C GY G C + C PR C+ G C +
Sbjct: 246 QR--SCPRGCSQRGRC----EGGRCVCDPGYTGDDCGMR--SC-PRGCSQRGRCEN---- 292
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
RC+C G++G ED C C G + D C C PG+TG++C R
Sbjct: 293 GRCVCNPGYTG---ED----CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----- 340
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRX---XXXXXXXXXXXDSXXXXXXXXXXX 613
+C E RC +G C E+ S R +
Sbjct: 341 -SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC 399
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C G TG C C CR GRC G +C C
Sbjct: 400 GVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSRAC-PRDCRGRGRCENG----VCVC 452
Query: 674 VAGWTGETCAVR 685
AG++GE C VR
Sbjct: 453 NAGYSGEDCGVR 464
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
G+ G G C C D +C C DG+ G C E+V G M
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRM 757
>AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYAGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (325), Expect = 1e-30
Identities = 149/535 (27%), Positives = 184/535 (34%), Gaps = 93/535 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYAGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C EG G C ++ C CR G C GS C C G+ GE C V
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 124 bits (298), Expect = 2e-27
Identities = 132/474 (27%), Positives = 156/474 (32%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+ G +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYAG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 100 bits (239), Expect = 3e-20
Identities = 92/336 (27%), Positives = 116/336 (34%), Gaps = 53/336 (15%)
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
TC C GW GP C++ D S A G C + C C G+TG C
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC- 213
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C G C C+ V C C AG++G CS PR C+ G C
Sbjct: 214 -GWPSCPGDCQGRGRCVQGV----CVCRAGFSGPDCS---QRSCPRGCSQRGRC----EG 261
Query: 497 YRCICPVGFSGTNC---------------EDDRDHC----AGSPCG-----NGAACYTAQ 532
RC+C G++G +C E+ R C AG CG G +
Sbjct: 262 GRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRGCSQRGRC 321
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRX--- 589
D C C PG+TG++C R +C E RC +G C E+ S R
Sbjct: 322 KDGRCVCDPGYTGEDCGTR------SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPR 375
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ G C C C G TG C
Sbjct: 376 DCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSR 433
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C CR GRC G +C C AG++GE C VR
Sbjct: 434 AC-PRDCRGRGRCENG----VCVCNAGYSGEDCGVR 464
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
G+ G G C C D +C C DG+ G C E+V G M
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRM 757
>AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYAGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (325), Expect = 1e-30
Identities = 149/535 (27%), Positives = 184/535 (34%), Gaps = 93/535 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYAGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C EG G C ++ C CR G C GS C C G+ GE C V
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 124 bits (298), Expect = 2e-27
Identities = 132/474 (27%), Positives = 156/474 (32%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+ G +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYAG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 100 bits (239), Expect = 3e-20
Identities = 92/336 (27%), Positives = 116/336 (34%), Gaps = 53/336 (15%)
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
TC C GW GP C++ D S A G C + C C G+TG C
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC- 213
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C G C C+ V C C AG++G CS PR C+ G C
Sbjct: 214 -GWPSCPGDCQGRGRCVQGV----CVCRAGFSGPDCS---QRSCPRGCSQRGRC----EG 261
Query: 497 YRCICPVGFSGTNC---------------EDDRDHC----AGSPCG-----NGAACYTAQ 532
RC+C G++G +C E+ R C AG CG G +
Sbjct: 262 GRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRGCSQRGRC 321
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRX--- 589
D C C PG+TG++C R +C E RC +G C E+ S R
Sbjct: 322 KDGRCVCDPGYTGEDCGTR------SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPR 375
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ G C C C G TG C
Sbjct: 376 DCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSR 433
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C CR GRC G +C C AG++GE C VR
Sbjct: 434 AC-PRDCRGRGRCENG----VCVCNAGYSGEDCGVR 464
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
G+ G G C C D +C C DG+ G C E+V G M
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRM 757
>AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 204 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 261
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 262 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYTGED----- 305
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 306 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 355
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 356 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 399
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 400 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 449
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 450 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 496
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 497 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 607
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 608 WEGYVSEDCSIR 619
Score = 134 bits (325), Expect = 1e-30
Identities = 149/535 (27%), Positives = 184/535 (34%), Gaps = 93/535 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 296 VCNPGYTGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 352
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 405
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 406 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 451
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 452 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 504
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 505 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 542
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 543 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 587
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 588 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 641
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 642 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C EG G C ++ C CR G C GS C C G+ GE C V
Sbjct: 702 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 126 bits (303), Expect = 5e-28
Identities = 133/474 (28%), Positives = 157/474 (33%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 214 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 258
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+TG +
Sbjct: 259 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYTG-------E 304
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 305 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 353
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 354 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 401
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 402 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 450
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 511 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 557
Score = 99.1 bits (236), Expect = 7e-20
Identities = 102/372 (27%), Positives = 129/372 (34%), Gaps = 65/372 (17%)
Query: 329 CSLAGT--TRGFTCTCDRGWGGXXXXXXXXX--------XASGPCLHGASCRDHLDGFTC 378
CSL G TC+C+ GWGG ASG C + + C
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 379 ECADGWTGPACA--EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C G+TGP+C +C GR G CV C C AG++G DC
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGR-------GRCVQGV----------CVCRAGFSGPDCS 245
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C C C + C C GY G C + C PR C+ G C +
Sbjct: 246 QR--SCPRGCSQRGRC----EGGRCVCDPGYTGDDCGMR--SC-PRGCSQRGRCEN---- 292
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
RC+C G++G ED C C G + D C C PG+TG++C R
Sbjct: 293 GRCVCNPGYTG---ED----CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----- 340
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRX---XXXXXXXXXXXDSXXXXXXXXXXX 613
+C E RC +G C E+ S R +
Sbjct: 341 -SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC 399
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C G TG C C CR GRC G +C C
Sbjct: 400 GVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSRAC-PRDCRGRGRCENG----VCVC 452
Query: 674 VAGWTGETCAVR 685
AG++GE C VR
Sbjct: 453 NAGYSGEDCGVR 464
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 544 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 600
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 601 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 655
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 656 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 706
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSM 401
G+ G G C C D +C C DG+ G C E+V G M
Sbjct: 707 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRM 757
>AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 230
Score = 143 bits (346), Expect = 3e-33
Identities = 72/197 (36%), Positives = 94/197 (47%), Gaps = 16/197 (8%)
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX- 357
+C+C EGF G C+ D PC C +G TC TC C G+ G
Sbjct: 11 YCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 358 -XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
S PCL+G +C D + C C G+TG C + D C PC N + C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH--------PCANGSTC 120
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
A +SC CL G+TG+ CET+V++C G C HG TC++L + C C G+ G+ C
Sbjct: 121 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 474 LDVDDCAPRPCTNGGEC 490
CAP PC NGG C
Sbjct: 181 SLYVPCAPSPCVNGGTC 197
Score = 127 bits (307), Expect = 2e-28
Identities = 64/185 (34%), Positives = 92/185 (49%), Gaps = 13/185 (7%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAP 541
C+C P
Sbjct: 207 CNCLP 211
Score = 122 bits (293), Expect = 8e-27
Identities = 72/215 (33%), Positives = 96/215 (44%), Gaps = 28/215 (13%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C+C +G+ G C + D C G G CV A G +C C +G+TG DC+
Sbjct: 12 CKCPEGFLGEYC-QHRDPCEKNRCQNG--GTCVAQAML----GKATCRCASGFTGEDCQY 64
Query: 438 NVDD-C--TGQCLHGATCIDLV-DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ C + CL+G TC L D + C C G+ G+ C D C PC NG C +
Sbjct: 65 STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTV 123
Query: 494 LNAYRCICPVGFSGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
N + C C GF+G CE D + C C +G C Y C C G+TG+ C
Sbjct: 124 ANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD--- 180
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
S+ V CA C NGGTC R+ G +
Sbjct: 181 -------SLYVP----CAPSPCVNGGTC-RQTGDF 203
Score = 105 bits (251), Expect = 1e-21
Identities = 60/174 (34%), Positives = 82/174 (47%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GGTC+ GS++
Sbjct: 127 FSCKCLTGFTGQKC----ETDVNECDI---------PGHCQHGGTCLNLPGSYQ 167
Score = 102 bits (245), Expect = 6e-21
Identities = 67/216 (31%), Positives = 90/216 (41%), Gaps = 23/216 (10%)
Query: 227 GDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG +C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACL-AGW 430
A PCVN C T + C CL A W
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPATW 214
Score = 101 bits (242), Expect = 1e-20
Identities = 71/225 (31%), Positives = 90/225 (40%), Gaps = 28/225 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GGTCL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGTCLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV-AGW 677
C +G TG C+ C SPC NGG C G + C C+ A W
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPATW 214
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 143 bits (346), Expect = 3e-33
Identities = 72/197 (36%), Positives = 94/197 (47%), Gaps = 16/197 (8%)
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX- 357
+C+C EGF G C+ D PC C +G TC TC C G+ G
Sbjct: 11 YCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 358 -XASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
S PCL+G +C D + C C G+TG C + D C PC N + C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH--------PCANGSTC 120
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
A +SC CL G+TG+ CET+V++C G C HG TC++L + C C G+ G+ C
Sbjct: 121 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 474 LDVDDCAPRPCTNGGEC 490
CAP PC NGG C
Sbjct: 181 SLYVPCAPSPCVNGGTC 197
Score = 130 bits (313), Expect = 3e-29
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAPGWTGKNCTQRAARDRK 557
C+C P T + T+ RDR+
Sbjct: 207 CNCLPE-TVRRGTELWERDRE 226
Score = 105 bits (251), Expect = 1e-21
Identities = 60/174 (34%), Positives = 82/174 (47%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GGTC+ GS++
Sbjct: 127 FSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGTCLNLPGSYQ 167
Score = 102 bits (244), Expect = 7e-21
Identities = 67/221 (30%), Positives = 90/221 (40%), Gaps = 22/221 (9%)
Query: 227 GDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG +C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRDCE 436
A PCVN C T + C CL R E
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPETVRRGTE 219
Score = 100 bits (240), Expect = 2e-20
Identities = 69/221 (31%), Positives = 88/221 (39%), Gaps = 27/221 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GGTCL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGTCLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB
(isoform 1)) protein.
Length = 4288
Score = 143 bits (346), Expect = 3e-33
Identities = 139/492 (28%), Positives = 180/492 (36%), Gaps = 80/492 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGC-KHGYCNG 256
C PG+ G +C P C C GRC + G C CR G+ G CSQ GC + G C G
Sbjct: 203 CFPGYTGPSCGWPSCPGDCQ-GRGRCVQ-GVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG 260
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C CD + G C + C C G CEN C C G++G D
Sbjct: 261 GR--CVCDPGYTGDDC--GMRSC--PRGCSQRGRCENGR-----CVCNPGYAGED----- 304
Query: 317 NPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
C + C G CS G + C CD G+ G C G C +DG
Sbjct: 305 --CGVRSCPRG-CSQRGRCKDGRCVCDPGYTG---EDCGTRSCPWDCGEGGRC---VDG- 354
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+TG ++CS R+ C C + C C G++G DC
Sbjct: 355 RCVCWPGYTG-------EDCSTRTCPR----DCRGRGRCEDG----ECICDTGYSGDDC- 398
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
V C G C C +D C C GY G C PR C G C + +
Sbjct: 399 -GVRSCPGDCNQRGRC----EDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV-- 448
Query: 497 YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
C+C G+SG +C C G G G C + + C C PG+TG++C RA
Sbjct: 449 --CVCNAGYSGEDC--GVRSCPGDCRGRG-RCESGR----CMCWPGYTGRDCGTRA---- 495
Query: 557 KTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDS--XXXXXXXXXXX 613
C RC +G C N G + GS R D
Sbjct: 496 --CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 553
Query: 614 XXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
G C C C +G +G C + C + C G C G +C C
Sbjct: 554 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDG----VCIC 606
Query: 674 VAGWTGETCAVR 685
G+ E C++R
Sbjct: 607 WEGYVSEDCSIR 618
Score = 134 bits (323), Expect = 2e-30
Identities = 148/531 (27%), Positives = 183/531 (34%), Gaps = 93/531 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C P Y C PR DG C PG+ G++C C C GRC
Sbjct: 295 VCNPGYAGEDCGVRSCPRG--CSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDC-GEGGRC 351
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCK-HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G C C PG+ GE CS C+ G C +C CDT + G D
Sbjct: 352 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSG----DDCGVRSCP 404
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCT 341
C G CE+ C C G++G DC + P+ C G C C
Sbjct: 405 GDCNQRGRCEDGR-----CVCWPGYTGTDC---GSRACPRDCRGRGRC------ENGVCV 450
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECSGR 399
C+ G+ G G C C + C C G+TG C +C GR
Sbjct: 451 CNAGYSG---EDCGVRSCPGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGR 503
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV+ C C G+TG DC + C G C C D V
Sbjct: 504 -------GRCVDG----------RCVCNPGFTGEDCGSR--RCPGDCRGHGLCEDGV--- 541
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C AGY+G CS C P C G+C+D RC+C G+SG ED C
Sbjct: 542 -CVCDAGYSGEDCS--TRSC-PGGCRGRGQCLD----GRCVCEDGYSG---ED----CGV 586
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA---- 575
C N + + D C C G+ ++C+ R TC RC EG C
Sbjct: 587 RQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR------TCPSNCHGRGRCEEGRCLCDPG 640
Query: 576 -NGGTCVRE--EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA-GGTCLPSALPPGW 631
G TC R A G C P L
Sbjct: 641 YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 700
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C EG G C ++ C CR G C GS C C G+ GE C
Sbjct: 701 QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDGS----CVCKDGYAGEDC 744
Score = 124 bits (298), Expect = 2e-27
Identities = 132/474 (27%), Positives = 156/474 (32%), Gaps = 89/474 (18%)
Query: 229 CDCRPGWRGELCS-----QCQP-YPGCKHGYCNGSSWD--------CTCDTNWGGILCDQ 274
C C PGW G CS + P P G C D C C + G C
Sbjct: 155 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 212
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
+ CQ G C Q C C GFSG DC + + C G CS G
Sbjct: 213 --GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDCSQ-------RSCPRG-CSQRGR 257
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C CD G+ G C G S R + C C G+ G +
Sbjct: 258 CEGGRCVCDPGYTGDDCGMRS-------CPRGCSQRGRCENGRCVCNPGYAG-------E 303
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C RS G C C + C C G+TG DC T C C G C+
Sbjct: 304 DCGVRSCPRG----CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCV- 352
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR 514
D C C GY G CS PR C G C D CIC G+SG +C
Sbjct: 353 ---DGRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GV 400
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C G C C D C C PG+TG +C RA C RC G+C
Sbjct: 401 RSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCGSRA------CPRDCRGRGRCENGVC 449
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXX---XXXXXXXXXXQAGGTCLPSALPPGW 631
E+ R +S G C
Sbjct: 450 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 509
Query: 632 ACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C G TG C C CR G C G +C C AG++GE C+ R
Sbjct: 510 RCVCNPGFTGEDC--GSRRC-PGDCRGHGLCEDG----VCVCDAGYSGEDCSTR 556
Score = 100 bits (239), Expect = 3e-20
Identities = 92/336 (27%), Positives = 116/336 (34%), Gaps = 53/336 (15%)
Query: 377 TCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
TC C GW GP C++ D S A G C + C C G+TG C
Sbjct: 154 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC- 212
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C G C C+ V C C AG++G CS PR C+ G C
Sbjct: 213 -GWPSCPGDCQGRGRCVQGV----CVCRAGFSGPDCS---QRSCPRGCSQRGRC----EG 260
Query: 497 YRCICPVGFSGTNC---------------EDDRDHC----AGSPCG-----NGAACYTAQ 532
RC+C G++G +C E+ R C AG CG G +
Sbjct: 261 GRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRGCSQRGRC 320
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRX--- 589
D C C PG+TG++C R +C E RC +G C E+ S R
Sbjct: 321 KDGRCVCDPGYTGEDCGTR------SCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPR 374
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ G C C C G TG C
Sbjct: 375 DCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC--GSR 432
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C CR GRC G +C C AG++GE C VR
Sbjct: 433 AC-PRDCRGRGRCENG----VCVCNAGYSGEDCGVR 463
Score = 76.2 bits (179), Expect = 5e-13
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 24/245 (9%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+T P + G C DG C G+ G++C C C HG C
Sbjct: 543 VCDAGYSGEDCSTRSCPGGCR-GRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQ-HGVC 599
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHE 283
+ G C C G+ E CS + P HG C CD + G C + C
Sbjct: 600 -QDGVCICWEGYVSEDCS-IRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM--CPAD- 654
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
C+ G C Q C C G+ G DC + + P + P G C R C C
Sbjct: 655 -CRGRGRCV-----QGVCLCHVGYGGEDCGQEEPPASACP---GGCGPRELCRAGQCVCV 705
Query: 344 RGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
G+ G G C C D +C C DG+ G C E S + +
Sbjct: 706 EGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGEDCGEARVPSSASAYDQ 758
Query: 404 GALGP 408
L P
Sbjct: 759 RGLAP 763
>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
protein protein.
Length = 4590
Score = 136 bits (330), Expect = 3e-31
Identities = 65/167 (38%), Positives = 86/167 (51%), Gaps = 6/167 (3%)
Query: 391 EDVDECSGRSMT---EGALGPCVNAAACN-NTAGGYSCACLAGWTGRDCETNVDDCTGQ- 445
E VD G +T + A PC N CN + AGGY C C A + G CE +V+ C+
Sbjct: 4003 ESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNP 4062
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CL+G TC+ F C C Y G+ C L C PC NGG C D L+ C C GF
Sbjct: 4063 CLYGGTCVVDNGGFVCQCRGLYTGQRCQLS-PYCKDEPCKNGGTCFDSLDGAVCQCDSGF 4121
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
G C+ D D C+G+PC +GA C Y+C+C+ + G++C A
Sbjct: 4122 RGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCEDAA 4168
Score = 123 bits (296), Expect = 4e-27
Identities = 59/154 (38%), Positives = 76/154 (49%), Gaps = 12/154 (7%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTC 342
PCQ+GG C + Y+C+C+ + G CE NPC+ PC + GTC + GF C C
Sbjct: 4023 PCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVV--DNGGFVCQC 4080
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
RG PC +G +C D LDG C+C G+ G C D+DECSG
Sbjct: 4081 -RGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSG---- 4135
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC++ A C NT G Y C C + GR CE
Sbjct: 4136 ----NPCLHGALCENTHGSYHCNCSHEYRGRHCE 4165
Score = 105 bits (252), Expect = 8e-22
Identities = 49/155 (31%), Positives = 73/155 (47%), Gaps = 9/155 (5%)
Query: 359 ASGPCLHGASCRDH-LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
AS PC +G C G+ C+C+ + G C V+ CS PC+ C
Sbjct: 4020 ASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSN--------PCLYGGTCVV 4071
Query: 418 TAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVD 477
GG+ C C +TG+ C+ + C +G TC D +D C C +G+ G C D+D
Sbjct: 4072 DNGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDID 4131
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCED 512
+C+ PC +G C + +Y C C + G +CED
Sbjct: 4132 ECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCED 4166
Score = 101 bits (243), Expect = 1e-20
Identities = 53/164 (32%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTC 378
CA PC +G G+ C C + G +S PCL+G +C GF C
Sbjct: 4019 CASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDNGGFVC 4078
Query: 379 ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETN 438
+C +TG C + S E PC N C ++ G C C +G+ G C+++
Sbjct: 4079 QCRGLYTGQRC-----QLSPYCKDE----PCKNGGTCFDSLDGAVCQCDSGFRGERCQSD 4129
Query: 439 VDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAP 481
+D+C+G CLHGA C + +HC C+ Y GR C +D AP
Sbjct: 4130 IDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHC----EDAAP 4169
Score = 65.7 bits (153), Expect = 8e-10
Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 16/105 (15%)
Query: 477 DDCAPRPCTNGGEC-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
+DCA PC NGG C Y C C + GT+CE + C+ +PC G C +
Sbjct: 4017 EDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDNGGF 4076
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
C C +TG+ C + S C + C NGGTC
Sbjct: 4077 VCQCRGLYTGQRC---------------QLSPYCKDEPCKNGGTC 4106
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/169 (26%), Positives = 62/169 (36%), Gaps = 22/169 (13%)
Query: 515 DHCAGSPCGNGAACYTAQSD-YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
+ CA +PC NG C + + YYC C+ + G +C SV C+
Sbjct: 4017 EDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCE---------ISV-----NPCSSNP 4062
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C GGTCV + G + + GGTC S G C
Sbjct: 4063 CLYGGTCVVDNGGF-----VCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSL--DGAVC 4115
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C G G C+ +D C +PC +G C G + C C + G C
Sbjct: 4116 QCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHC 4164
Score = 60.1 bits (139), Expect = 4e-08
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 17/153 (11%)
Query: 205 DNCEKPVCKEG--CHPTHGRCDRPGDCDCRPGWRGELC----SQCQPYPGCKHGYC--NG 256
++C C+ G C+P+ C C + G C + C P G C +
Sbjct: 4017 EDCASNPCQNGGVCNPSPAGGYY---CKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDN 4073
Query: 257 SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
+ C C + G C Q YC EPC++GGTC ++ D C+C GF G C+
Sbjct: 4074 GGFVCQCRGLYTGQRC-QLSPYC-KDEPCKNGGTCFDSL-DGAVCQCDSGFRGERCQSDI 4130
Query: 317 NPCAPQPCAHGTCSLAGTTRG-FTCTCDRGWGG 348
+ C+ PC HG +L T G + C C + G
Sbjct: 4131 DECSGNPCLHG--ALCENTHGSYHCNCSHEYRG 4161
Score = 40.7 bits (91), Expect = 0.025
Identities = 42/133 (31%), Positives = 54/133 (40%), Gaps = 33/133 (24%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPT--HGRC--DRPGD-CDCRPGWRGELCSQCQPY---PGC 249
C + G +CE V +P G C D G C CR + G+ C Q PY C
Sbjct: 4042 CSALYIGTHCEISVNPCSSNPCLYGGTCVVDNGGFVCQCRGLYTGQRC-QLSPYCKDEPC 4100
Query: 250 KHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENT------------ 294
K+G S D C CD+ + G C D++ C + PC HG CENT
Sbjct: 4101 KNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGN-PCLHGALCENTHGSYHCNCSHEY 4159
Query: 295 --------APDQY 299
AP+QY
Sbjct: 4160 RGRHCEDAAPNQY 4172
Score = 37.1 bits (82), Expect = 0.31
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 651 CGSSPCRNGGRC-VGGSGWWMCECVAGWTGETCAVRVS 687
C S+PC+NGG C +G + C+C A + G C + V+
Sbjct: 4019 CASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVN 4056
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 136 bits (330), Expect = 3e-31
Identities = 137/500 (27%), Positives = 196/500 (39%), Gaps = 69/500 (13%)
Query: 211 VCKEG--CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
VC G HP+ C +C R +G+ +C G +C T T+
Sbjct: 871 VCSPGYQLHPSQAYCTDDNEC-LRDPCKGK--GRCINRVGSYSCFCYPGY---TLATSGA 924
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV---DCERVDNPCAPQPCA 325
C QD+N C C GG C NT Y C C +G+ V C+ ++ P C
Sbjct: 925 TQEC-QDINECEQPGVCS-GGQCTNTE-GSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 326 HGTCSLAGTTRGFTC-TCDRGWGGXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECAD 382
G C + +TC C+ G+ G P C HG C + F C C
Sbjct: 982 DGRC--VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ 1038
Query: 383 GW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRD--- 434
G+ + +DVDEC+ R+ L C NT G ++C AC G W D
Sbjct: 1039 GYEVTSDEKGCQDVDECASRASCPTGL--------CLNTEGSFACSACENGYWVNEDGTA 1090
Query: 435 CETNVDDCT--GQCLHGATCIDLVDDFHCA-CAAGYA----GRTCSLDVDDCA-PRPCTN 486
CE ++D+C G C G C + F C C GY G +C DVD+C P+
Sbjct: 1091 CE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCL 1147
Query: 487 GGECVDLLNAYRCICPVGF---SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
GGEC + + +Y+C+CP GF +GT CED + C C + ++C CAPG+
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF 1207
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
+A +C ++ + CA GG CV EGS+ +S
Sbjct: 1208 V-------SAEGGTSC----QDVDECATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESG 1255
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCREG---RTGALCELSLDLCGS-SPCR 657
GT P + C GC+ G C + +D C + + C
Sbjct: 1256 ECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCG 1314
Query: 658 NGGRCVGGSGWWMCECVAGW 677
+ G C G + C C G+
Sbjct: 1315 SHGFCDNTDGSFRCLCDQGF 1334
Score = 124 bits (298), Expect = 2e-27
Identities = 122/425 (28%), Positives = 166/425 (39%), Gaps = 70/425 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH------GYCNG 256
+ CE+P VC G C T G C+C G+ CQ C+H G C
Sbjct: 932 NECEQPGVCSGGQCTNTEGSYH----CECDQGYIMVRKGHCQDINECRHPGTCPDGRCVN 987
Query: 257 S--SWDC-TCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD- 311
S S+ C C+ + G D+N C T C HG C N + C C +G+
Sbjct: 988 SPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLE-GSFRCSCEQGYEVTSD 1045
Query: 312 ---CERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGW----GGXXXXXXXXXXASGPC 363
C+ VD + C G C T F C+ C+ G+ G G C
Sbjct: 1046 EKGCQDVDECASRASCPTGLC--LNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVC 1103
Query: 364 LHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G C + F+C+ DG P+ EDVDEC E C+ C NT
Sbjct: 1104 PSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC------EDPQSSCLGGE-CKNTV 1155
Query: 420 GGYSCACLAGW---TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA---GRT 471
G Y C C G+ G CE +V++C G+ C C++ F C CA G+ G T
Sbjct: 1156 GSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 472 CSLDVDDCAPR-PCTNGGECVDLLNAYRCICPVGF-----SGTNCEDDRDHCAGSPCGNG 525
DVD+CA PC GG CV+ ++ C+C GF SG + D G P
Sbjct: 1215 SCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGT 1273
Query: 526 AACYTAQSDYYC--HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
C + Y C C PG+ C ++ E + MC + G C
Sbjct: 1274 WKCENSPGSYRCVLGCQPGF--------HMAPNGDC---IDIDECANDTMCGSHGFCDNT 1322
Query: 584 EGSWR 588
+GS+R
Sbjct: 1323 DGSFR 1327
Score = 93.9 bits (223), Expect = 3e-18
Identities = 104/402 (25%), Positives = 151/402 (37%), Gaps = 65/402 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRCDR-PGD--CDCRPGW---- 235
G Y+C C G++G + E P HG+C G C C G+
Sbjct: 990 GSYTCLA-----CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTS 1044
Query: 236 --RG-ELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----- 287
+G + +C C G C + C G ++D C + C
Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCP 1104
Query: 288 GGTCENTAPDQYFCR-CAEGFS----GVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCT 341
G C NTA + C+ C G+ G CE VD PQ C G C T + C
Sbjct: 1105 SGVCTNTA-GSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECK--NTVGSYQCL 1161
Query: 342 CDRGW---GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDE 395
C +G+ G C C + F C CA G+ G +DVDE
Sbjct: 1162 CPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1221
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT--GQCLHG 449
C+ PCV C NT G ++C C G+ +C ++D+C G + G
Sbjct: 1222 CA-------TTDPCVGGH-CVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCG 1272
Query: 450 A-TCIDLVDDFHCA--CAAGY--AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPV 503
C + + C C G+ A +D+D+CA C + G C + ++RC+C
Sbjct: 1273 TWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQ 1332
Query: 504 GF----SGTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCA 540
GF SG +C D + + CG A C + + C CA
Sbjct: 1333 GFEISPSGWDCVDVNECELMLAVCG-AALCENVEGSFLCLCA 1373
Score = 91.1 bits (216), Expect = 2e-17
Identities = 128/506 (25%), Positives = 180/506 (35%), Gaps = 84/506 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCD--CRPGWRGELCS---QCQ-PYPGCKHGYCNG 256
D C P VC G C T G DCD RP G+ C +C+ P C G C
Sbjct: 1095 DECAFPGVCPSGVCTNTAGSFSCK-DCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153
Query: 257 S--SWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF---- 307
+ S+ C C + G +C+ D+N C E C G C N+ +FC CA GF
Sbjct: 1154 TVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSH-GSFFCLCAPGFVSAE 1211
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGP 362
G C+ VD PC G C T F C C+ G+ G P
Sbjct: 1212 GGTSCQDVDECATTDPCVGGHC--VNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1269
Query: 363 CLHGASCRDHLDGFTCE--CADGWTGPACAE--DVDECSGRSMTEGALGPCVNAAACNNT 418
C + + C C G+ + D+DEC+ +M C + C+NT
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-------CGSHGFCDNT 1322
Query: 419 AGGYSCACLAGW----TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGRTC 472
G + C C G+ +G DC +V++C A C ++ F C CA+
Sbjct: 1323 DGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLE---- 1377
Query: 473 SLDVDDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
D + RP GG+ + + P + +C + +PC + T
Sbjct: 1378 EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAP---TRMDCYSGQK--GHAPCSSVLGRNTT 1432
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Q++ C W G C + D E SE +C +G + EG+W
Sbjct: 1433 QAECCCTQGASW-GDACDLCPSEDS------AEFSE-----ICPSGKGYIPVEGAW---T 1477
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D G CL + PG+ C C G + CE
Sbjct: 1478 FGQTMYTDADECVIFGPGLC------PNGRCLNTV--PGYVCLCNPGFHYDASHKKCE-D 1528
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC 673
D C C N G CV G + C C
Sbjct: 1529 HDECQDLACEN-GECVNTEGSFHCFC 1553
Score = 85.8 bits (203), Expect = 7e-16
Identities = 86/341 (25%), Positives = 130/341 (38%), Gaps = 48/341 (14%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
A+ C G +C + DG+ C C+ G+ P+ A D+ E PC C N
Sbjct: 852 ATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDD------NECLRDPCKGKGRCIN 904
Query: 418 TAGGYSCACLAGWT------GRDCETNVDDC--TGQCLHGATCIDLVDDFHCACAAGY-- 467
G YSC C G+T ++C+ ++++C G C G C + +HC C GY
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQ-DINECEQPGVC-SGGQCTNTEGSYHCECDQGYIM 962
Query: 468 AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGFSGT--NCEDDRDHCAGSPCG 523
+ D+++C P C + G CV+ +Y C+ C G+ G +C D + C
Sbjct: 963 VRKGHCQDINECRHPGTCPD-GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCA 1021
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
+G C + + C C G+ D K C ++ + CA G C+
Sbjct: 1022 HG-KCTNLEGSFRCSCEQGY-------EVTSDEKGC----QDVDECASRASCPTGLCLNT 1069
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC-----GCREG 638
EGS+ D G C +A ++C G R
Sbjct: 1070 EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTA--GSFSCKDCDGGYRPS 1127
Query: 639 RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
G CE +D C S C GG C G + C C G+
Sbjct: 1128 PLGDSCE-DVDECEDPQSSCL-GGECKNTVGSYQCLCPQGF 1166
Score = 79.8 bits (188), Expect = 4e-14
Identities = 112/421 (26%), Positives = 158/421 (37%), Gaps = 80/421 (19%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC-DRPGD--CDCRPGW----RGE 238
G Y C G ++ + + +E C P HG C + G C C PG+ G
Sbjct: 1156 GSYQCLCPQGFQLANGTVCEDVNECMGEEHCAP-HGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 239 LCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--- 290
C +C C G+C + S++C C+T G + C + C+ G
Sbjct: 1215 SCQDVDECATTDPCVGGHCVNTEGSFNCLCET---GFQPSPESGECVDIDECEDYGDPVC 1271
Query: 291 ----CENTAPDQYFC--RCAEGFSGV---DCERVDNPCAPQPC-AHGTCSLAGTTRGFTC 340
CEN+ P Y C C GF DC +D C +HG C T F C
Sbjct: 1272 GTWKCENS-PGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCD--NTDGSFRC 1328
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVD 394
CD+G+ G C GA+ ++++G F C CA E+ D
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVC--GAALCENVEGSFLCLCASD------LEEYD 1380
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYS-CACLAGWTGR-DCETNVDDCTGQ----CLH 448
G GA G ++ A + A + C +G G C + + T Q C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 449 GATCIDLVD--------DFH--CACAAGYA--------GRTCSLDVDDCA---PRPCTNG 487
GA+ D D +F C GY G+T D D+C P C NG
Sbjct: 1441 GASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG 1500
Query: 488 GECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C++ + Y C+C GF S CE D D C C NG C + ++C C+P
Sbjct: 1501 -RCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPL 1557
Query: 544 T 544
T
Sbjct: 1558 T 1558
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 198 CLPGWQGDN----CEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C PGW N C KPVC+ C G C RP C CR G+RG C + P
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQ-NRGSCSRPQLCVCRSGFRGARCEEVIP 223
Score = 38.7 bits (86), Expect = 0.10
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 620 GTCLPSALPPGWACGCREGR----TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
GTC+ LP G+ C C G + A C + C PC+ GRC+ G + C C
Sbjct: 859 GTCVN--LPDGYRCVCSPGYQLHPSQAYCTDDNE-CLRDPCKGKGRCINRVGSYSCFCYP 915
Query: 676 GWT 678
G+T
Sbjct: 916 GYT 918
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C +G+ A DV+EC + G CV+ C NT
Sbjct: 1743 CENGRCVRVR-EGYTCDCFEGFQLDAAHMACVDVNECDDLN---GPAVLCVHGY-CENTE 1797
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQ 445
G Y C C G+ E CT +
Sbjct: 1798 GSYRCHCSPGYV---AEAGPPHCTAK 1820
Score = 35.5 bits (78), Expect = 0.95
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF----SGTNCED--DRDHCA 518
AG+ G L ++C G CV + Y C C GF + C D + D
Sbjct: 1727 AGFEG----LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLN 1782
Query: 519 GSP--CGNGAACYTAQSDYYCHCAPGWTGK 546
G C +G C + Y CHC+PG+ +
Sbjct: 1783 GPAVLCVHGY-CENTEGSYRCHCSPGYVAE 1811
Score = 33.5 bits (73), Expect = 3.8
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 11/83 (13%)
Query: 234 GWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG-----GILCDQDLNYC----GTHEP 284
G+ G +C GC++G C TCD G + D+N C G
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVL 1787
Query: 285 CQHGGTCENTAPDQYFCRCAEGF 307
C H G CENT Y C C+ G+
Sbjct: 1788 CVH-GYCENT-EGSYRCHCSPGY 1808
Score = 33.1 bits (72), Expect = 5.1
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
PC NGGRC+G W C A TG+ C
Sbjct: 403 PCLNGGRCIGRDECW---CPANSTGKFC 427
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 136 bits (330), Expect = 3e-31
Identities = 137/500 (27%), Positives = 196/500 (39%), Gaps = 69/500 (13%)
Query: 211 VCKEG--CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
VC G HP+ C +C R +G+ +C G +C T T+
Sbjct: 871 VCSPGYQLHPSQAYCTDDNEC-LRDPCKGK--GRCINRVGSYSCFCYPGY---TLATSGA 924
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV---DCERVDNPCAPQPCA 325
C QD+N C C GG C NT Y C C +G+ V C+ ++ P C
Sbjct: 925 TQEC-QDINECEQPGVCS-GGQCTNTE-GSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 326 HGTCSLAGTTRGFTC-TCDRGWGGXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECAD 382
G C + +TC C+ G+ G P C HG C + F C C
Sbjct: 982 DGRC--VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ 1038
Query: 383 GW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRD--- 434
G+ + +DVDEC+ R+ L C NT G ++C AC G W D
Sbjct: 1039 GYEVTSDEKGCQDVDECASRASCPTGL--------CLNTEGSFACSACENGYWVNEDGTA 1090
Query: 435 CETNVDDCT--GQCLHGATCIDLVDDFHCA-CAAGYA----GRTCSLDVDDCA-PRPCTN 486
CE ++D+C G C G C + F C C GY G +C DVD+C P+
Sbjct: 1091 CE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCL 1147
Query: 487 GGECVDLLNAYRCICPVGF---SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
GGEC + + +Y+C+CP GF +GT CED + C C + ++C CAPG+
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF 1207
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
+A +C ++ + CA GG CV EGS+ +S
Sbjct: 1208 V-------SAEGGTSC----QDVDECATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESG 1255
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCREG---RTGALCELSLDLCGS-SPCR 657
GT P + C GC+ G C + +D C + + C
Sbjct: 1256 ECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCG 1314
Query: 658 NGGRCVGGSGWWMCECVAGW 677
+ G C G + C C G+
Sbjct: 1315 SHGFCDNTDGSFRCLCDQGF 1334
Score = 124 bits (298), Expect = 2e-27
Identities = 122/425 (28%), Positives = 166/425 (39%), Gaps = 70/425 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH------GYCNG 256
+ CE+P VC G C T G C+C G+ CQ C+H G C
Sbjct: 932 NECEQPGVCSGGQCTNTEGSYH----CECDQGYIMVRKGHCQDINECRHPGTCPDGRCVN 987
Query: 257 S--SWDC-TCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD- 311
S S+ C C+ + G D+N C T C HG C N + C C +G+
Sbjct: 988 SPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLE-GSFRCSCEQGYEVTSD 1045
Query: 312 ---CERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGW----GGXXXXXXXXXXASGPC 363
C+ VD + C G C T F C+ C+ G+ G G C
Sbjct: 1046 EKGCQDVDECASRASCPTGLC--LNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVC 1103
Query: 364 LHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G C + F+C+ DG P+ EDVDEC E C+ C NT
Sbjct: 1104 PSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC------EDPQSSCLGGE-CKNTV 1155
Query: 420 GGYSCACLAGW---TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA---GRT 471
G Y C C G+ G CE +V++C G+ C C++ F C CA G+ G T
Sbjct: 1156 GSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 472 CSLDVDDCAPR-PCTNGGECVDLLNAYRCICPVGF-----SGTNCEDDRDHCAGSPCGNG 525
DVD+CA PC GG CV+ ++ C+C GF SG + D G P
Sbjct: 1215 SCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGT 1273
Query: 526 AACYTAQSDYYC--HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
C + Y C C PG+ C ++ E + MC + G C
Sbjct: 1274 WKCENSPGSYRCVLGCQPGF--------HMAPNGDC---IDIDECANDTMCGSHGFCDNT 1322
Query: 584 EGSWR 588
+GS+R
Sbjct: 1323 DGSFR 1327
Score = 93.9 bits (223), Expect = 3e-18
Identities = 104/402 (25%), Positives = 151/402 (37%), Gaps = 65/402 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRCDR-PGD--CDCRPGW---- 235
G Y+C C G++G + E P HG+C G C C G+
Sbjct: 990 GSYTCLA-----CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTS 1044
Query: 236 --RG-ELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----- 287
+G + +C C G C + C G ++D C + C
Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCP 1104
Query: 288 GGTCENTAPDQYFCR-CAEGFS----GVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCT 341
G C NTA + C+ C G+ G CE VD PQ C G C T + C
Sbjct: 1105 SGVCTNTA-GSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECK--NTVGSYQCL 1161
Query: 342 CDRGW---GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDE 395
C +G+ G C C + F C CA G+ G +DVDE
Sbjct: 1162 CPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1221
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT--GQCLHG 449
C+ PCV C NT G ++C C G+ +C ++D+C G + G
Sbjct: 1222 CA-------TTDPCVGGH-CVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCG 1272
Query: 450 A-TCIDLVDDFHCA--CAAGY--AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPV 503
C + + C C G+ A +D+D+CA C + G C + ++RC+C
Sbjct: 1273 TWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQ 1332
Query: 504 GF----SGTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCA 540
GF SG +C D + + CG A C + + C CA
Sbjct: 1333 GFEISPSGWDCVDVNECELMLAVCG-AALCENVEGSFLCLCA 1373
Score = 91.1 bits (216), Expect = 2e-17
Identities = 128/506 (25%), Positives = 180/506 (35%), Gaps = 84/506 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCD--CRPGWRGELCS---QCQ-PYPGCKHGYCNG 256
D C P VC G C T G DCD RP G+ C +C+ P C G C
Sbjct: 1095 DECAFPGVCPSGVCTNTAGSFSCK-DCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153
Query: 257 S--SWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF---- 307
+ S+ C C + G +C+ D+N C E C G C N+ +FC CA GF
Sbjct: 1154 TVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSH-GSFFCLCAPGFVSAE 1211
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGP 362
G C+ VD PC G C T F C C+ G+ G P
Sbjct: 1212 GGTSCQDVDECATTDPCVGGHC--VNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1269
Query: 363 CLHGASCRDHLDGFTCE--CADGWTGPACAE--DVDECSGRSMTEGALGPCVNAAACNNT 418
C + + C C G+ + D+DEC+ +M C + C+NT
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-------CGSHGFCDNT 1322
Query: 419 AGGYSCACLAGW----TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGRTC 472
G + C C G+ +G DC +V++C A C ++ F C CA+
Sbjct: 1323 DGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLE---- 1377
Query: 473 SLDVDDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
D + RP GG+ + + P + +C + +PC + T
Sbjct: 1378 EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAP---TRMDCYSGQK--GHAPCSSVLGRNTT 1432
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Q++ C W G C + D E SE +C +G + EG+W
Sbjct: 1433 QAECCCTQGASW-GDACDLCPSEDS------AEFSE-----ICPSGKGYIPVEGAW---T 1477
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D G CL + PG+ C C G + CE
Sbjct: 1478 FGQTMYTDADECVIFGPGLC------PNGRCLNTV--PGYVCLCNPGFHYDASHKKCE-D 1528
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC 673
D C C N G CV G + C C
Sbjct: 1529 HDECQDLACEN-GECVNTEGSFHCFC 1553
Score = 85.8 bits (203), Expect = 7e-16
Identities = 86/341 (25%), Positives = 130/341 (38%), Gaps = 48/341 (14%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
A+ C G +C + DG+ C C+ G+ P+ A D+ E PC C N
Sbjct: 852 ATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDD------NECLRDPCKGKGRCIN 904
Query: 418 TAGGYSCACLAGWT------GRDCETNVDDC--TGQCLHGATCIDLVDDFHCACAAGY-- 467
G YSC C G+T ++C+ ++++C G C G C + +HC C GY
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQ-DINECEQPGVC-SGGQCTNTEGSYHCECDQGYIM 962
Query: 468 AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGFSGT--NCEDDRDHCAGSPCG 523
+ D+++C P C + G CV+ +Y C+ C G+ G +C D + C
Sbjct: 963 VRKGHCQDINECRHPGTCPD-GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCA 1021
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
+G C + + C C G+ D K C ++ + CA G C+
Sbjct: 1022 HG-KCTNLEGSFRCSCEQGY-------EVTSDEKGC----QDVDECASRASCPTGLCLNT 1069
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC-----GCREG 638
EGS+ D G C +A ++C G R
Sbjct: 1070 EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTA--GSFSCKDCDGGYRPS 1127
Query: 639 RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
G CE +D C S C GG C G + C C G+
Sbjct: 1128 PLGDSCE-DVDECEDPQSSCL-GGECKNTVGSYQCLCPQGF 1166
Score = 79.8 bits (188), Expect = 4e-14
Identities = 112/421 (26%), Positives = 158/421 (37%), Gaps = 80/421 (19%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC-DRPGD--CDCRPGW----RGE 238
G Y C G ++ + + +E C P HG C + G C C PG+ G
Sbjct: 1156 GSYQCLCPQGFQLANGTVCEDVNECMGEEHCAP-HGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 239 LCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--- 290
C +C C G+C + S++C C+T G + C + C+ G
Sbjct: 1215 SCQDVDECATTDPCVGGHCVNTEGSFNCLCET---GFQPSPESGECVDIDECEDYGDPVC 1271
Query: 291 ----CENTAPDQYFC--RCAEGFSGV---DCERVDNPCAPQPC-AHGTCSLAGTTRGFTC 340
CEN+ P Y C C GF DC +D C +HG C T F C
Sbjct: 1272 GTWKCENS-PGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCD--NTDGSFRC 1328
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVD 394
CD+G+ G C GA+ ++++G F C CA E+ D
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVC--GAALCENVEGSFLCLCASD------LEEYD 1380
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYS-CACLAGWTGR-DCETNVDDCTGQ----CLH 448
G GA G ++ A + A + C +G G C + + T Q C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 449 GATCIDLVD--------DFH--CACAAGYA--------GRTCSLDVDDCA---PRPCTNG 487
GA+ D D +F C GY G+T D D+C P C NG
Sbjct: 1441 GASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG 1500
Query: 488 GECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C++ + Y C+C GF S CE D D C C NG C + ++C C+P
Sbjct: 1501 -RCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPL 1557
Query: 544 T 544
T
Sbjct: 1558 T 1558
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 198 CLPGWQGDN----CEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C PGW N C KPVC+ C G C RP C CR G+RG C + P
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQ-NRGSCSRPQLCVCRSGFRGARCEEVIP 223
Score = 38.7 bits (86), Expect = 0.10
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 620 GTCLPSALPPGWACGCREGR----TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
GTC+ LP G+ C C G + A C + C PC+ GRC+ G + C C
Sbjct: 859 GTCVN--LPDGYRCVCSPGYQLHPSQAYCTDDNE-CLRDPCKGKGRCINRVGSYSCFCYP 915
Query: 676 GWT 678
G+T
Sbjct: 916 GYT 918
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C +G+ A DV+EC + G CV+ C NT
Sbjct: 1743 CENGRCVRVR-EGYTCDCFEGFQLDAAHMACVDVNECDDLN---GPAVLCVHGY-CENTE 1797
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQ 445
G Y C C G+ E CT +
Sbjct: 1798 GSYRCHCSPGYV---AEAGPPHCTAK 1820
Score = 35.5 bits (78), Expect = 0.95
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF----SGTNCED--DRDHCA 518
AG+ G L ++C G CV + Y C C GF + C D + D
Sbjct: 1727 AGFEG----LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLN 1782
Query: 519 GSP--CGNGAACYTAQSDYYCHCAPGWTGK 546
G C +G C + Y CHC+PG+ +
Sbjct: 1783 GPAVLCVHGY-CENTEGSYRCHCSPGYVAE 1811
Score = 33.5 bits (73), Expect = 3.8
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 11/83 (13%)
Query: 234 GWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG-----GILCDQDLNYC----GTHEP 284
G+ G +C GC++G C TCD G + D+N C G
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVL 1787
Query: 285 CQHGGTCENTAPDQYFCRCAEGF 307
C H G CENT Y C C+ G+
Sbjct: 1788 CVH-GYCENT-EGSYRCHCSPGY 1808
Score = 33.1 bits (72), Expect = 5.1
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
PC NGGRC+G W C A TG+ C
Sbjct: 403 PCLNGGRCIGRDECW---CPANSTGKFC 427
>AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ14712 fis, clone NT2RP3000825, weakly similar to
NEUROGENIC LOCUS NOTCH 3 PROTEIN. ).
Length = 849
Score = 136 bits (330), Expect = 3e-31
Identities = 93/314 (29%), Positives = 134/314 (42%), Gaps = 47/314 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C PG+ G NC+ +C C HG+C +P C C PG G C + P C+HG +
Sbjct: 575 CKPGYIGSNCQTALCDPDCK-NHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGICLA 633
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
CTC + G C+ + C H C++GG C PD C+C G+ G C
Sbjct: 634 GNLCTCPYGFVGPRCETMV--CNRH--CENGGQC--LTPD--ICQCKPGWYGPTCSTA-- 683
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
C P G+C+ + TC C G+ G PC +G C +
Sbjct: 684 LCDPVCLNGGSCN-----KPNTCLCPNGFFG---EHCQNAFCHPPCKNGGHC---MRNNV 732
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C +G+TG C + + C C+N C G +C+C +GW+G+ C T
Sbjct: 733 CVCREGYTGRRCQKSI--CD---------PTCMNGGKC---VGPSTCSCPSGWSGKRCNT 778
Query: 438 NVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAY 497
+ C +C +G CI C C + + G C + + C P+ C GG C+ N
Sbjct: 779 PI--CLQKCKNGGECI---APSICHCPSSWEGVRCQIPI--CNPK-CLYGGRCI-FPNV- 828
Query: 498 RCICPVGFSGTNCE 511
C C +SG CE
Sbjct: 829 -CSCRTEYSGVKCE 841
Score = 108 bits (259), Expect = 1e-22
Identities = 87/288 (30%), Positives = 112/288 (38%), Gaps = 52/288 (18%)
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C + G C L C C++ G C P+ C+C G G C+ + C
Sbjct: 573 CKCKPGYIGSNCQTAL--CDPD--CKNHGKC--IKPN--ICQCLPGHGGATCD--EEHCN 622
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCEC 380
P PC HG LAG CTC G+ G + C +G C L C+C
Sbjct: 623 P-PCQHGGICLAGNL----CTCPYGFVGPRCETMV---CNRHCENGGQC---LTPDICQC 671
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
GW GP C+ + C C+N +CN +C C G+ G C+
Sbjct: 672 KPGWYGPTCSTAL--CDP---------VCLNGGSCNKPN---TCLCPNGFFGEHCQNAF- 716
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C C +G C+ + C C GY GR C + C P C NGG+CV C
Sbjct: 717 -CHPPCKNGGHCMR---NNVCVCREGYTGRRCQKSI--CDPT-CMNGGKCV---GPSTCS 766
Query: 501 CPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
CP G+SG C + C C NG C CHC W G C
Sbjct: 767 CPSGWSGKRC--NTPICL-QKCKNGGECIAPS---ICHCPSSWEGVRC 808
Score = 101 bits (242), Expect = 1e-20
Identities = 86/310 (27%), Positives = 113/310 (36%), Gaps = 46/310 (14%)
Query: 165 CQPNYYNTTC-TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
C+P Y + C T C P D H C CLPG G C++ C C HG
Sbjct: 575 CKPGYIGSNCQTALCDP--DCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQ--HGGI 630
Query: 224 DRPGD-CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH 282
G+ C C G+ G C C++G + C C W G C L C
Sbjct: 631 CLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTAL--C--D 686
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTC 342
C +GG+C P+ C C GF G C+ C P PC +G R C C
Sbjct: 687 PVCLNGGSCNK--PNT--CLCPNGFFGEHCQNAF--CHP-PCKNG----GHCMRNNVCVC 735
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
G+ G C++G C + TC C GW+G C +
Sbjct: 736 REGYTG---RRCQKSICDPTCMNGGKC---VGPSTCSCPSGWSGKRCNTPI--------- 780
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCA 462
L C N C C C + W G C+ + C +CL+G CI C+
Sbjct: 781 --CLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI--CNPKCLYGGRCI---FPNVCS 830
Query: 463 CAAGYAGRTC 472
C Y+G C
Sbjct: 831 CRTEYSGVKC 840
Score = 92.3 bits (219), Expect = 8e-18
Identities = 99/412 (24%), Positives = 137/412 (33%), Gaps = 51/412 (12%)
Query: 285 CQHGGTC---ENTAPDQ--YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFT 339
C +GG+C N +P Y C C GF G CE + C PC G S ++
Sbjct: 442 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLG--SYISGFHSYS 499
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
C C + D + D V SG
Sbjct: 500 CDCPPELKVETQFVNKFTTQTVVLTRS-------DKSVNKEEDDKNAQGRKRHVKPTSGN 552
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
+ T PC + C C C G+ G +C+T + C C + CI
Sbjct: 553 AFTICKY-PCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPDCKNHGKCIK---PN 603
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C G+ G TC D + C P PC +GG C L C CP GF G CE
Sbjct: 604 ICQCLPGHGGATC--DEEHCNP-PCQHGGIC---LAGNLCTCPYGFVGPRCET---MVCN 654
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
C NG C T C C PGW G C+ + C +C NG
Sbjct: 655 RHCENGGQCLTPD---ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTC---LCPNGFF 708
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG----- 634
+ ++ ++ ++ C P+ + G G
Sbjct: 709 GEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRCQKS--ICDPTCMNGGKCVGPSTCS 766
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C G +G C + L C+NGG C+ S +C C + W G C + +
Sbjct: 767 CPSGWSGKRCNTPICL---QKCKNGGECIAPS---ICHCPSSWEGVRCQIPI 812
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/153 (31%), Positives = 67/153 (43%), Gaps = 14/153 (9%)
Query: 164 LCQPNYYNTTC-TTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
LC ++ C FC P GH C + C G+ G C+K +C C G+
Sbjct: 702 LCPNGFFGEHCQNAFCHPPCKNGGH--CMRNNVCVCREGYTGRRCQKSICDPTCM-NGGK 758
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYPGCKHG-YCNGSSWDCTCDTNWGGILCDQDLNYCGT 281
C P C C GW G+ C+ CK+G C S C C ++W G+ C + C
Sbjct: 759 CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSI-CHCPSSWEGVRCQ--IPIC-- 813
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
+ C +GG C P+ C C +SGV CE+
Sbjct: 814 NPKCLYGGRC--IFPN--VCSCRTEYSGVKCEK 842
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/114 (27%), Positives = 43/114 (37%), Gaps = 4/114 (3%)
Query: 164 LCQPNYYNTTCT-TFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGR 222
+C+ Y C + C P G C C GW G C P+C + C G
Sbjct: 734 VCREGYTGRRCQKSICDPTCMNGG--KCVGPSTCSCPSGWSGKRCNTPICLQKCK-NGGE 790
Query: 223 CDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDL 276
C P C C W G C P C +G C+C T + G+ C++ +
Sbjct: 791 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 844
Score = 41.5 bits (93), Expect = 0.014
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 9/73 (12%)
Query: 436 ETNVDDCTGQCLHGATCIDLVDD------FHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
E V C CL+G +C+ + + C C G+ G C +D+ C PC G
Sbjct: 434 EVTVKSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGS 490
Query: 490 CVDLLNAYRCICP 502
+ ++Y C CP
Sbjct: 491 YISGFHSYSCDCP 503
Score = 35.5 bits (78), Expect = 0.95
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 6/41 (14%)
Query: 653 SSPCRNGGRCVG------GSGWWMCECVAGWTGETCAVRVS 687
S C NGG CV GSG ++C C+ G+ G C V +S
Sbjct: 439 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS 479
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 136 bits (330), Expect = 3e-31
Identities = 137/500 (27%), Positives = 196/500 (39%), Gaps = 69/500 (13%)
Query: 211 VCKEG--CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
VC G HP+ C +C R +G+ +C G +C T T+
Sbjct: 750 VCSPGYQLHPSQAYCTDDNEC-LRDPCKGK--GRCINRVGSYSCFCYPGY---TLATSGA 803
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV---DCERVDNPCAPQPCA 325
C QD+N C C GG C NT Y C C +G+ V C+ ++ P C
Sbjct: 804 TQEC-QDINECEQPGVCS-GGQCTNTE-GSYHCECDQGYIMVRKGHCQDINECRHPGTCP 860
Query: 326 HGTCSLAGTTRGFTC-TCDRGWGGXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECAD 382
G C + +TC C+ G+ G P C HG C + F C C
Sbjct: 861 DGRC--VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ 917
Query: 383 GW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRD--- 434
G+ + +DVDEC+ R+ L C NT G ++C AC G W D
Sbjct: 918 GYEVTSDEKGCQDVDECASRASCPTGL--------CLNTEGSFACSACENGYWVNEDGTA 969
Query: 435 CETNVDDCT--GQCLHGATCIDLVDDFHCA-CAAGYA----GRTCSLDVDDCA-PRPCTN 486
CE ++D+C G C G C + F C C GY G +C DVD+C P+
Sbjct: 970 CE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCL 1026
Query: 487 GGECVDLLNAYRCICPVGF---SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
GGEC + + +Y+C+CP GF +GT CED + C C + ++C CAPG+
Sbjct: 1027 GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF 1086
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
+A +C ++ + CA GG CV EGS+ +S
Sbjct: 1087 V-------SAEGGTSC----QDVDECATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESG 1134
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCREG---RTGALCELSLDLCGS-SPCR 657
GT P + C GC+ G C + +D C + + C
Sbjct: 1135 ECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCG 1193
Query: 658 NGGRCVGGSGWWMCECVAGW 677
+ G C G + C C G+
Sbjct: 1194 SHGFCDNTDGSFRCLCDQGF 1213
Score = 124 bits (298), Expect = 2e-27
Identities = 122/425 (28%), Positives = 166/425 (39%), Gaps = 70/425 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH------GYCNG 256
+ CE+P VC G C T G C+C G+ CQ C+H G C
Sbjct: 811 NECEQPGVCSGGQCTNTEGSYH----CECDQGYIMVRKGHCQDINECRHPGTCPDGRCVN 866
Query: 257 S--SWDC-TCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD- 311
S S+ C C+ + G D+N C T C HG C N + C C +G+
Sbjct: 867 SPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLE-GSFRCSCEQGYEVTSD 924
Query: 312 ---CERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGW----GGXXXXXXXXXXASGPC 363
C+ VD + C G C T F C+ C+ G+ G G C
Sbjct: 925 EKGCQDVDECASRASCPTGLC--LNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVC 982
Query: 364 LHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G C + F+C+ DG P+ EDVDEC E C+ C NT
Sbjct: 983 PSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC------EDPQSSCLGGE-CKNTV 1034
Query: 420 GGYSCACLAGW---TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA---GRT 471
G Y C C G+ G CE +V++C G+ C C++ F C CA G+ G T
Sbjct: 1035 GSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1093
Query: 472 CSLDVDDCAPR-PCTNGGECVDLLNAYRCICPVGF-----SGTNCEDDRDHCAGSPCGNG 525
DVD+CA PC GG CV+ ++ C+C GF SG + D G P
Sbjct: 1094 SCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGT 1152
Query: 526 AACYTAQSDYYC--HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
C + Y C C PG+ C ++ E + MC + G C
Sbjct: 1153 WKCENSPGSYRCVLGCQPGF--------HMAPNGDC---IDIDECANDTMCGSHGFCDNT 1201
Query: 584 EGSWR 588
+GS+R
Sbjct: 1202 DGSFR 1206
Score = 93.9 bits (223), Expect = 3e-18
Identities = 104/402 (25%), Positives = 151/402 (37%), Gaps = 65/402 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRCDR-PGD--CDCRPGW---- 235
G Y+C C G++G + E P HG+C G C C G+
Sbjct: 869 GSYTCLA-----CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTS 923
Query: 236 --RG-ELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----- 287
+G + +C C G C + C G ++D C + C
Sbjct: 924 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCP 983
Query: 288 GGTCENTAPDQYFCR-CAEGFS----GVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCT 341
G C NTA + C+ C G+ G CE VD PQ C G C T + C
Sbjct: 984 SGVCTNTA-GSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECK--NTVGSYQCL 1040
Query: 342 CDRGW---GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDE 395
C +G+ G C C + F C CA G+ G +DVDE
Sbjct: 1041 CPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1100
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT--GQCLHG 449
C+ PCV C NT G ++C C G+ +C ++D+C G + G
Sbjct: 1101 CA-------TTDPCVGGH-CVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCG 1151
Query: 450 A-TCIDLVDDFHCA--CAAGY--AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPV 503
C + + C C G+ A +D+D+CA C + G C + ++RC+C
Sbjct: 1152 TWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQ 1211
Query: 504 GF----SGTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCA 540
GF SG +C D + + CG A C + + C CA
Sbjct: 1212 GFEISPSGWDCVDVNECELMLAVCG-AALCENVEGSFLCLCA 1252
Score = 91.1 bits (216), Expect = 2e-17
Identities = 128/506 (25%), Positives = 180/506 (35%), Gaps = 84/506 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCD--CRPGWRGELCS---QCQ-PYPGCKHGYCNG 256
D C P VC G C T G DCD RP G+ C +C+ P C G C
Sbjct: 974 DECAFPGVCPSGVCTNTAGSFSCK-DCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1032
Query: 257 S--SWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF---- 307
+ S+ C C + G +C+ D+N C E C G C N+ +FC CA GF
Sbjct: 1033 TVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSH-GSFFCLCAPGFVSAE 1090
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGP 362
G C+ VD PC G C T F C C+ G+ G P
Sbjct: 1091 GGTSCQDVDECATTDPCVGGHC--VNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1148
Query: 363 CLHGASCRDHLDGFTCE--CADGWTGPACAE--DVDECSGRSMTEGALGPCVNAAACNNT 418
C + + C C G+ + D+DEC+ +M C + C+NT
Sbjct: 1149 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-------CGSHGFCDNT 1201
Query: 419 AGGYSCACLAGW----TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGRTC 472
G + C C G+ +G DC +V++C A C ++ F C CA+
Sbjct: 1202 DGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLE---- 1256
Query: 473 SLDVDDCAPRPCTNGGECV-DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
D + RP GG+ + + P + +C + +PC + T
Sbjct: 1257 EYDAQEGHCRPRGAGGQSMSEAPTGDHAPAP---TRMDCYSGQK--GHAPCSSVLGRNTT 1311
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXX 591
Q++ C W G C + D E SE +C +G + EG+W
Sbjct: 1312 QAECCCTQGASW-GDACDLCPSEDS------AEFSE-----ICPSGKGYIPVEGAW---T 1356
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D G CL + PG+ C C G + CE
Sbjct: 1357 FGQTMYTDADECVIFGPGLC------PNGRCLNTV--PGYVCLCNPGFHYDASHKKCE-D 1407
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC 673
D C C N G CV G + C C
Sbjct: 1408 HDECQDLACEN-GECVNTEGSFHCFC 1432
Score = 85.8 bits (203), Expect = 7e-16
Identities = 86/341 (25%), Positives = 130/341 (38%), Gaps = 48/341 (14%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
A+ C G +C + DG+ C C+ G+ P+ A D+ E PC C N
Sbjct: 731 ATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDD------NECLRDPCKGKGRCIN 783
Query: 418 TAGGYSCACLAGWT------GRDCETNVDDC--TGQCLHGATCIDLVDDFHCACAAGY-- 467
G YSC C G+T ++C+ ++++C G C G C + +HC C GY
Sbjct: 784 RVGSYSCFCYPGYTLATSGATQECQ-DINECEQPGVC-SGGQCTNTEGSYHCECDQGYIM 841
Query: 468 AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGFSGT--NCEDDRDHCAGSPCG 523
+ D+++C P C + G CV+ +Y C+ C G+ G +C D + C
Sbjct: 842 VRKGHCQDINECRHPGTCPD-GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCA 900
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
+G C + + C C G+ D K C ++ + CA G C+
Sbjct: 901 HG-KCTNLEGSFRCSCEQGY-------EVTSDEKGC----QDVDECASRASCPTGLCLNT 948
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC-----GCREG 638
EGS+ D G C +A ++C G R
Sbjct: 949 EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTA--GSFSCKDCDGGYRPS 1006
Query: 639 RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
G CE +D C S C GG C G + C C G+
Sbjct: 1007 PLGDSCE-DVDECEDPQSSCL-GGECKNTVGSYQCLCPQGF 1045
Score = 79.8 bits (188), Expect = 4e-14
Identities = 112/421 (26%), Positives = 158/421 (37%), Gaps = 80/421 (19%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC-DRPGD--CDCRPGW----RGE 238
G Y C G ++ + + +E C P HG C + G C C PG+ G
Sbjct: 1035 GSYQCLCPQGFQLANGTVCEDVNECMGEEHCAP-HGECLNSHGSFFCLCAPGFVSAEGGT 1093
Query: 239 LCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--- 290
C +C C G+C + S++C C+T G + C + C+ G
Sbjct: 1094 SCQDVDECATTDPCVGGHCVNTEGSFNCLCET---GFQPSPESGECVDIDECEDYGDPVC 1150
Query: 291 ----CENTAPDQYFC--RCAEGFSGV---DCERVDNPCAPQPC-AHGTCSLAGTTRGFTC 340
CEN+ P Y C C GF DC +D C +HG C T F C
Sbjct: 1151 GTWKCENS-PGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCD--NTDGSFRC 1207
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVD 394
CD+G+ G C GA+ ++++G F C CA E+ D
Sbjct: 1208 LCDQGFEISPSGWDCVDVNECELMLAVC--GAALCENVEGSFLCLCASD------LEEYD 1259
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYS-CACLAGWTGR-DCETNVDDCTGQ----CLH 448
G GA G ++ A + A + C +G G C + + T Q C
Sbjct: 1260 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1319
Query: 449 GATCIDLVD--------DFH--CACAAGYA--------GRTCSLDVDDCA---PRPCTNG 487
GA+ D D +F C GY G+T D D+C P C NG
Sbjct: 1320 GASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG 1379
Query: 488 GECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C++ + Y C+C GF S CE D D C C NG C + ++C C+P
Sbjct: 1380 -RCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPL 1436
Query: 544 T 544
T
Sbjct: 1437 T 1437
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 198 CLPGWQGDN----CEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C PGW N C KPVC+ C G C RP C CR G+RG C + P
Sbjct: 52 CCPGWTTANSTNHCIKPVCEPPCQ-NRGSCSRPQLCVCRSGFRGARCEEVIP 102
Score = 38.7 bits (86), Expect = 0.10
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 620 GTCLPSALPPGWACGCREGR----TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
GTC+ LP G+ C C G + A C + C PC+ GRC+ G + C C
Sbjct: 738 GTCVN--LPDGYRCVCSPGYQLHPSQAYCTDDNE-CLRDPCKGKGRCINRVGSYSCFCYP 794
Query: 676 GWT 678
G+T
Sbjct: 795 GYT 797
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C +G+ A DV+EC + G CV+ C NT
Sbjct: 1622 CENGRCVRVR-EGYTCDCFEGFQLDAAHMACVDVNECDDLN---GPAVLCVHGY-CENTE 1676
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQ 445
G Y C C G+ E CT +
Sbjct: 1677 GSYRCHCSPGYV---AEAGPPHCTAK 1699
Score = 35.5 bits (78), Expect = 0.95
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF----SGTNCED--DRDHCA 518
AG+ G L ++C G CV + Y C C GF + C D + D
Sbjct: 1606 AGFEG----LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLN 1661
Query: 519 GSP--CGNGAACYTAQSDYYCHCAPGWTGK 546
G C +G C + Y CHC+PG+ +
Sbjct: 1662 GPAVLCVHGY-CENTEGSYRCHCSPGYVAE 1690
Score = 33.5 bits (73), Expect = 3.8
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 11/83 (13%)
Query: 234 GWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG-----GILCDQDLNYC----GTHEP 284
G+ G +C GC++G C TCD G + D+N C G
Sbjct: 1607 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVL 1666
Query: 285 CQHGGTCENTAPDQYFCRCAEGF 307
C H G CENT Y C C+ G+
Sbjct: 1667 CVH-GYCENT-EGSYRCHCSPGY 1687
Score = 33.1 bits (72), Expect = 5.1
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
PC NGGRC+G W C A TG+ C
Sbjct: 282 PCLNGGRCIGRDECW---CPANSTGKFC 306
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 136 bits (329), Expect = 4e-31
Identities = 137/500 (27%), Positives = 196/500 (39%), Gaps = 69/500 (13%)
Query: 211 VCKEG--CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
VC G HP+ C +C R +G+ +C G +C T T+
Sbjct: 871 VCSPGYQLHPSQAYCTDDNEC-LRDPCQGK--GRCINRVGSYSCFCYPGY---TLATSGA 924
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV---DCERVDNPCAPQPCA 325
C QD+N C C GG C NT Y C C +G+ V C+ ++ P C
Sbjct: 925 TQEC-QDINECEQPGVCS-GGQCTNTE-GSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 326 HGTCSLAGTTRGFTC-TCDRGWGGXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECAD 382
G C + +TC C+ G+ G P C HG C + F C C
Sbjct: 982 DGRC--VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ 1038
Query: 383 GW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRD--- 434
G+ + +DVDEC+ R+ L C NT G ++C AC G W D
Sbjct: 1039 GYEVTSDEKGCQDVDECASRASCPTGL--------CLNTEGSFACSACENGYWVNEDGTA 1090
Query: 435 CETNVDDCT--GQCLHGATCIDLVDDFHCA-CAAGYA----GRTCSLDVDDCA-PRPCTN 486
CE ++D+C G C G C + F C C GY G +C DVD+C P+
Sbjct: 1091 CE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCL 1147
Query: 487 GGECVDLLNAYRCICPVGF---SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
GGEC + + +Y+C+CP GF +GT CED + C C + ++C CAPG+
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF 1207
Query: 544 TGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
+A +C ++ + CA GG CV EGS+ +S
Sbjct: 1208 V-------SAEGGTSC----QDVDECATTDPCVGGHCVNTEGSFN-CLCETGFQPSPESG 1255
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWAC--GCREG---RTGALCELSLDLCGS-SPCR 657
GT P + C GC+ G C + +D C + + C
Sbjct: 1256 ECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCG 1314
Query: 658 NGGRCVGGSGWWMCECVAGW 677
+ G C G + C C G+
Sbjct: 1315 SHGFCDNTDGSFRCLCDQGF 1334
Score = 124 bits (298), Expect = 2e-27
Identities = 122/425 (28%), Positives = 166/425 (39%), Gaps = 70/425 (16%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH------GYCNG 256
+ CE+P VC G C T G C+C G+ CQ C+H G C
Sbjct: 932 NECEQPGVCSGGQCTNTEGSYH----CECDQGYIMVRKGHCQDINECRHPGTCPDGRCVN 987
Query: 257 S--SWDC-TCDTNWGGILCD-QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD- 311
S S+ C C+ + G D+N C T C HG C N + C C +G+
Sbjct: 988 SPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLE-GSFRCSCEQGYEVTSD 1045
Query: 312 ---CERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGW----GGXXXXXXXXXXASGPC 363
C+ VD + C G C T F C+ C+ G+ G G C
Sbjct: 1046 EKGCQDVDECASRASCPTGLC--LNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVC 1103
Query: 364 LHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G C + F+C+ DG P+ EDVDEC E C+ C NT
Sbjct: 1104 PSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC------EDPQSSCLGGE-CKNTV 1155
Query: 420 GGYSCACLAGW---TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA---GRT 471
G Y C C G+ G CE +V++C G+ C C++ F C CA G+ G T
Sbjct: 1156 GSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 472 CSLDVDDCAPR-PCTNGGECVDLLNAYRCICPVGF-----SGTNCEDDRDHCAGSPCGNG 525
DVD+CA PC GG CV+ ++ C+C GF SG + D G P
Sbjct: 1215 SCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGT 1273
Query: 526 AACYTAQSDYYC--HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
C + Y C C PG+ C ++ E + MC + G C
Sbjct: 1274 WKCENSPGSYRCVLGCQPGF--------HMAPNGDC---IDIDECANDTMCGSHGFCDNT 1322
Query: 584 EGSWR 588
+GS+R
Sbjct: 1323 DGSFR 1327
Score = 93.9 bits (223), Expect = 3e-18
Identities = 104/402 (25%), Positives = 151/402 (37%), Gaps = 65/402 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHP---THGRCDR-PGD--CDCRPGW---- 235
G Y+C C G++G + E P HG+C G C C G+
Sbjct: 990 GSYTCLA-----CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTS 1044
Query: 236 --RG-ELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----- 287
+G + +C C G C + C G ++D C + C
Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCP 1104
Query: 288 GGTCENTAPDQYFCR-CAEGFS----GVDCERVDNPCAPQP-CAHGTCSLAGTTRGFTCT 341
G C NTA + C+ C G+ G CE VD PQ C G C T + C
Sbjct: 1105 SGVCTNTA-GSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECK--NTVGSYQCL 1161
Query: 342 CDRGW---GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDE 395
C +G+ G C C + F C CA G+ G +DVDE
Sbjct: 1162 CPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1221
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT--GQCLHG 449
C+ PCV C NT G ++C C G+ +C ++D+C G + G
Sbjct: 1222 CA-------TTDPCVGGH-CVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCG 1272
Query: 450 A-TCIDLVDDFHCA--CAAGY--AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPV 503
C + + C C G+ A +D+D+CA C + G C + ++RC+C
Sbjct: 1273 TWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQ 1332
Query: 504 GF----SGTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCA 540
GF SG +C D + + CG A C + + C CA
Sbjct: 1333 GFEISPSGWDCVDVNECELMLAVCG-AALCENVEGSFLCLCA 1373
Score = 90.6 bits (215), Expect = 2e-17
Identities = 128/509 (25%), Positives = 177/509 (34%), Gaps = 90/509 (17%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCD--CRPGWRGELCS---QCQ-PYPGCKHGYCNG 256
D C P VC G C T G DCD RP G+ C +C+ P C G C
Sbjct: 1095 DECAFPGVCPSGVCTNTAGSFSCK-DCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153
Query: 257 S--SWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF---- 307
+ S+ C C + G +C+ D+N C E C G C N+ +FC CA GF
Sbjct: 1154 TVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSH-GSFFCLCAPGFVSAE 1211
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGP 362
G C+ VD PC G C T F C C+ G+ G P
Sbjct: 1212 GGTSCQDVDECATTDPCVGGHC--VNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1269
Query: 363 CLHGASCRDHLDGFTCE--CADGWTGPACAE--DVDECSGRSMTEGALGPCVNAAACNNT 418
C + + C C G+ + D+DEC+ +M C + C+NT
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-------CGSHGFCDNT 1322
Query: 419 AGGYSCACLAGW----TGRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGRTC 472
G + C C G+ +G DC +V++C A C ++ F C CA+
Sbjct: 1323 DGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLE---- 1377
Query: 473 SLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ 532
D + RP GG+ + P G DH +P CY+ Q
Sbjct: 1378 EYDAQEGHCRPRGAGGQSMS-------EAPTG----------DH---APAPTRMDCYSGQ 1417
Query: 533 SDYY-CHCAPG---WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C G + C + A C + E +C +G + EG+W
Sbjct: 1418 KGHAPCSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAW- 1476
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALC 644
D G CL + PG+ C C G + C
Sbjct: 1477 --TFGQTMYTDADECVIFGPGLC------PNGRCLNTV--PGYVCLCNPGFHYDASHKKC 1526
Query: 645 ELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
E D C C N G CV G + C C
Sbjct: 1527 E-DHDECQDLACEN-GECVNTEGSFHCFC 1553
Score = 85.8 bits (203), Expect = 7e-16
Identities = 86/341 (25%), Positives = 130/341 (38%), Gaps = 48/341 (14%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
A+ C G +C + DG+ C C+ G+ P+ A D+ E PC C N
Sbjct: 852 ATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDD------NECLRDPCQGKGRCIN 904
Query: 418 TAGGYSCACLAGWT------GRDCETNVDDC--TGQCLHGATCIDLVDDFHCACAAGY-- 467
G YSC C G+T ++C+ ++++C G C G C + +HC C GY
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQ-DINECEQPGVC-SGGQCTNTEGSYHCECDQGYIM 962
Query: 468 AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGFSGT--NCEDDRDHCAGSPCG 523
+ D+++C P C + G CV+ +Y C+ C G+ G +C D + C
Sbjct: 963 VRKGHCQDINECRHPGTCPD-GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCA 1021
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
+G C + + C C G+ D K C ++ + CA G C+
Sbjct: 1022 HG-KCTNLEGSFRCSCEQGY-------EVTSDEKGC----QDVDECASRASCPTGLCLNT 1069
Query: 584 EGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC-----GCREG 638
EGS+ D G C +A ++C G R
Sbjct: 1070 EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTA--GSFSCKDCDGGYRPS 1127
Query: 639 RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
G CE +D C S C GG C G + C C G+
Sbjct: 1128 PLGDSCE-DVDECEDPQSSCL-GGECKNTVGSYQCLCPQGF 1166
Score = 81.4 bits (192), Expect = 1e-14
Identities = 113/421 (26%), Positives = 158/421 (37%), Gaps = 80/421 (19%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC-DRPGD--CDCRPGW----RGE 238
G Y C G ++ + + +E C P HG C + G C C PG+ G
Sbjct: 1156 GSYQCLCPQGFQLANGTVCEDVNECMGEEHCAP-HGECLNSHGSFFCLCAPGFVSAEGGT 1214
Query: 239 LCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGT--- 290
C +C C G+C + S++C C+T G + C + C+ G
Sbjct: 1215 SCQDVDECATTDPCVGGHCVNTEGSFNCLCET---GFQPSPESGECVDIDECEDYGDPVC 1271
Query: 291 ----CENTAPDQYFC--RCAEGFSGV---DCERVDNPCAPQPC-AHGTCSLAGTTRGFTC 340
CEN+ P Y C C GF DC +D C +HG C T F C
Sbjct: 1272 GTWKCENS-PGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCD--NTDGSFRC 1328
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG-FTCECADGWTGPACAEDVD 394
CD+G+ G C GA+ ++++G F C CA E+ D
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVC--GAALCENVEGSFLCLCASD------LEEYD 1380
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYS-CACLAGWTGR-DCETNVDDCTGQ----CLH 448
G GA G ++ A + A + C +G G C + + T Q C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 449 GATCIDLVD--------DFH--CACAAGYA--------GRTCSLDVDDCA---PRPCTNG 487
GAT D D +F C GY G+T D D+C P C NG
Sbjct: 1441 GATWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG 1500
Query: 488 GECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C++ + Y C+C GF S CE D D C C NG C + ++C C+P
Sbjct: 1501 -RCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPL 1557
Query: 544 T 544
T
Sbjct: 1558 T 1558
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 198 CLPGWQGDN----CEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C PGW N C KPVC+ C G C RP C CR G+RG C + P
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQ-NRGSCSRPQLCVCRSGFRGARCEEVIP 223
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 620 GTCLPSALPPGWACGCREGR----TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
GTC+ LP G+ C C G + A C + C PC+ GRC+ G + C C
Sbjct: 859 GTCVN--LPDGYRCVCSPGYQLHPSQAYCTDDNE-CLRDPCQGKGRCINRVGSYSCFCYP 915
Query: 676 GWT 678
G+T
Sbjct: 916 GYT 918
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C +G+ A DV+EC + G CV+ C NT
Sbjct: 1743 CENGRCVRVR-EGYTCDCFEGFQLDAAHMACVDVNECDDLN---GPAVLCVHGY-CENTE 1797
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQ 445
G Y C C G+ E CT +
Sbjct: 1798 GSYRCHCSPGYV---AEAGPPHCTAK 1820
Score = 35.5 bits (78), Expect = 0.95
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 465 AGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF----SGTNCED--DRDHCA 518
AG+ G L ++C G CV + Y C C GF + C D + D
Sbjct: 1727 AGFEG----LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLN 1782
Query: 519 GSP--CGNGAACYTAQSDYYCHCAPGWTGK 546
G C +G C + Y CHC+PG+ +
Sbjct: 1783 GPAVLCVHGY-CENTEGSYRCHCSPGYVAE 1811
Score = 33.5 bits (73), Expect = 3.8
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 11/83 (13%)
Query: 234 GWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWG-----GILCDQDLNYC----GTHEP 284
G+ G +C GC++G C TCD G + D+N C G
Sbjct: 1728 GFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVL 1787
Query: 285 CQHGGTCENTAPDQYFCRCAEGF 307
C H G CENT Y C C+ G+
Sbjct: 1788 CVH-GYCENT-EGSYRCHCSPGY 1808
Score = 33.1 bits (72), Expect = 5.1
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETC 682
PC NGGRC+G W C A TG+ C
Sbjct: 403 PCLNGGRCIGRDECW---CPANSTGKFC 427
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 136 bits (328), Expect = 5e-31
Identities = 155/563 (27%), Positives = 200/563 (35%), Gaps = 96/563 (17%)
Query: 194 GDKHCLPGWQGDNCEKPV--------CKEGCHPTH--GRCD-RPGDCDCRPGWRGELCSQ 242
G C PG G++CE C+E C RCD G C C PG+ G C
Sbjct: 651 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD 710
Query: 243 CQPY----PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
P P C+ G+C+ ++ C+C W G C + + C H C
Sbjct: 711 VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC 770
Query: 292 E--NTAPDQY--FCRCAEGFSGVDCERV-----DNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+ + D C C G+ G CE+ P Q C + G CTC
Sbjct: 771 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG-ACTC 829
Query: 343 DRGWGGXXXXXXXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
GW G G C GA+C D ++G +C C G GP CAE +
Sbjct: 830 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAE---K 884
Query: 396 CSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV------DDCTGQCL 447
C R + G G C+N C+ G C C AGWTG C++ + C +C
Sbjct: 885 CLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 942
Query: 448 --HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP-------CTNGGECVDLLNAYR 498
GA C + C C G+ G C P C NGG C A
Sbjct: 943 CPPGAACHHVTG--ACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA-- 998
Query: 499 CICPVGFSGTNCE---------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
C CP GF GT+C + H G CG GAAC C C PG G C
Sbjct: 999 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGT--CLCPPGRAGVRCE 1054
Query: 550 QRAARDRKTCSVLVEESERCAE-GMC-ANGGTCVREEG-SWRXXXXXXXXXXXXDSXXXX 606
+ ++R V E + C G+C A+ G+C G + R +
Sbjct: 1055 RGCPQNR--FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE 1112
Query: 607 XXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNG 659
A GTC P + C R+GA C L P C G
Sbjct: 1113 CSCHNNSTCEPATGTC--RCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGG 1170
Query: 660 GRCVGGSGWWMCECVAGWTGETC 682
C SG C CV G+ G TC
Sbjct: 1171 ADCDPVSG--QCHCVDGYMGPTC 1191
Score = 128 bits (310), Expect = 7e-29
Identities = 168/609 (27%), Positives = 201/609 (33%), Gaps = 93/609 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGC 216
C YY C C + H G C PG G C P C E C
Sbjct: 493 CPKGYYGKHCRKKCNCANRGRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 549
Query: 217 H---PTHGRCD-RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWD-CTCDTNWGGIL 271
P CD R G C C+ G+RGE C Q + C+ GY W CTC G+
Sbjct: 550 QCVQPHTQSCDKRDGSCSCKAGFRGERC-QAE----CELGYFGPGCWQACTCPV---GVA 601
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC--AHGTC 329
CD CG + C G E+ + C G GV+C C PC G C
Sbjct: 602 CDSVSGECG--KRCPAGFQGEDCGQE-----CPVGTFGVNCSS-SCSCGGAPCHGVTGQC 653
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
G C D G A C H A C D G C C G+ G C
Sbjct: 654 RCPPGRTGEDCEADCPEGRWGLGCQEICPA---CQHAARC-DPETG-ACLCLPGFVGSRC 708
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD------DCT 443
+DV + C N C+ G C+C GWTG C+ D DC+
Sbjct: 709 -QDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCS 765
Query: 444 G--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD------CAPR-PCTNGGECVDLL 494
C G D + C C AGY G C C R C +G C +
Sbjct: 766 HPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVS 824
Query: 495 NAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
A C CP G+ GT CE D + C GAAC C C G G
Sbjct: 825 GA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGRRGPR 880
Query: 548 CTQRA-ARD-RKTCSVLVEESERCAE-GMC-ANGGTCVREEGSWRXXXXXX--XXXXXXD 601
C ++ RD R C S C G+C + G C+ G W +
Sbjct: 881 CAEKCLPRDVRAGC----RHSGGCLNGGLCDPHTGRCLCPAG-WTGDKCQSPCLRGWFGE 935
Query: 602 SXXXXXXXXXXXXXXQAGGTCL--PSALPPGWACGCREGRTGALCELSLDLCGSSPCRNG 659
+ G C P G GC GR G CE LCG C NG
Sbjct: 936 ACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCE---QLCG---CLNG 989
Query: 660 GRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPA 719
G C +G C C G+ G C + + T CLC
Sbjct: 990 GSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT-CLC-- 1044
Query: 720 PPQRAARRC 728
PP RA RC
Sbjct: 1045 PPGRAGVRC 1053
Score = 122 bits (295), Expect = 5e-27
Identities = 133/463 (28%), Positives = 169/463 (36%), Gaps = 88/463 (19%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--------PVCKE 214
+C +Y +C T C +D GH C P G C PGW G +C++ P C
Sbjct: 711 VCPAGWYGPSCQTRCSCAND--GH--CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSH 766
Query: 215 GCHPT--HGRCDR-PGDCDCRPGWRGELCSQCQPY----PGCK------HGY-CNGSSWD 260
C+ + HG CD G C C G+ G C Q P PGC+ HG C+ S
Sbjct: 767 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA 826
Query: 261 CTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
CTC W G C+ C + C G C+ C C G G C
Sbjct: 827 CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS---CLCPAGRRGPRCAE 883
Query: 315 VDNPCAPQP----CAH-GTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP----- 362
C P+ C H G C G T C C GW G G
Sbjct: 884 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR 940
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA+C H+ G C C G+TG C + E G C+N +C+ G
Sbjct: 941 CSCPPGAACH-HVTG-ACRCPPGFTGSGCEQGCPPGRYGPGCEQLCG-CLNGGSCDAATG 997
Query: 421 GYSCACLAGWTGRDCETNVD------DCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
+C C G+ G DC +CT C GA C + C C G AG C
Sbjct: 998 --ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRC 1053
Query: 473 SLDVDD------CAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCE----DDRDHCA--- 518
C C NGG C N C C +G++G +CE R A
Sbjct: 1054 ERGCPQNRFGVGCEHTCSCRNGGLC-HASNG-SCSCGLGWTGRHCELACPPGRYGAACHL 1111
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
C N + C A C C PG+ G+ C R R TC++
Sbjct: 1112 ECSCHNNSTCEPATGT--CRCGPGFYGQACEHR--RSGATCNL 1150
Score = 107 bits (257), Expect = 2e-22
Identities = 112/390 (28%), Positives = 140/390 (35%), Gaps = 62/390 (15%)
Query: 198 CLPGWQGDNCEKPV--------CKEGCHPTHGR-CDRP-GDCDCRPGWRGELCSQ-CQPY 246
C GW+G CE C+ C+ T G CD G C C G RG C++ C P
Sbjct: 829 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPR 888
Query: 247 P---GCKH-------GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
GC+H G C+ + C C W G C E C +C A
Sbjct: 889 DVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAA 948
Query: 297 DQYF---CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL--AGTTRGFT--CTCDRGWGGX 349
+ CRC GF+G CE+ P P C G+ T C C G+ G
Sbjct: 949 CHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGT 1008
Query: 350 XXXXXXXXXASGP-CLH------GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
GP C H GA+C D + G TC C G G C +
Sbjct: 1009 DCNLTCPQGRFGPNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGC 1066
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCA 462
E C N C+ + G SC+C GWTGR CE G+ +GA C C+
Sbjct: 1067 EHTCS-CRNGGLCHASNG--SCSCGLGWTGRHCELACP--PGR--YGAAC-----HLECS 1114
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC--ICPVGFSGTNCEDDRDHCAGS 520
C + TC C P G C + C C G G +C HC
Sbjct: 1115 C---HNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSC---TLHC--- 1165
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
CG GA C CHC G+ G C +
Sbjct: 1166 DCGGGADCDPVSGQ--CHCVDGYMGPTCRE 1193
Score = 101 bits (241), Expect = 2e-20
Identities = 107/325 (32%), Positives = 125/325 (38%), Gaps = 64/325 (19%)
Query: 275 DLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCA--PQPCAHG 327
D++ C TH CQH C NT P Y C C GF C + N CA C H
Sbjct: 56 DVDECRTHNGGCQH--RCVNT-PGSYLCECKPGFRLHTDSRTCLAI-NSCALGNGGCQHH 111
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
L T C C G+ G +G C+H C+ CEC
Sbjct: 112 CVQLTITRH--RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHV 167
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRD 434
G+ G AC EDVDEC+ L C A C NT G + C C AG+ GR
Sbjct: 168 GYQLAADGKAC-EDVDECAA------GLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ 218
Query: 435 C---ETN-VDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRP 483
C E V+ C G C HG C C C GY RTC +DVDDCA P
Sbjct: 219 CYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTC-IDVDDCADSP 275
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C C + Y C C G+ G CED D CA S G C + C C
Sbjct: 276 CCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDV-DECASSRGGCEHHCTNLAGSFQCSC 333
Query: 540 APGWTGKNCTQRAARDRKTCSVLVE 564
G+ R DR+ CS L E
Sbjct: 334 EAGY-------RLHEDRRGCSPLEE 351
Score = 96.7 bits (230), Expect = 4e-19
Identities = 97/335 (28%), Positives = 124/335 (37%), Gaps = 58/335 (17%)
Query: 261 CTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C C W G++C++ C CQ+GGTC++ CRC G SG +CE
Sbjct: 435 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA---CRCPPGVSGTNCED 491
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGP-------C 363
C+ A R C CD G G A GP C
Sbjct: 492 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 551
Query: 364 L--HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN--AAACNNTA 419
+ H SC D DG +C C G+ G C EC G C AC++ +
Sbjct: 552 VQPHTQSC-DKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVS 606
Query: 420 GGYSCACLAGWTGRDC--ETNVD----DCTGQC-LHGATCIDLVDDFHCACAAGYAGRTC 472
G C AG+ G DC E V +C+ C GA C + C C G G C
Sbjct: 607 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ--CRCPPGRTGEDC 664
Query: 473 SLDVDD------CAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--- 521
D + C C + C A C+C GF G+ C+D P
Sbjct: 665 EADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQ 722
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
C N C+ A +C CAPGWTG +C QRA
Sbjct: 723 TRCSCANDGHCHPATG--HCSCAPGWTGFSC-QRA 754
Score = 81.0 bits (191), Expect = 2e-14
Identities = 126/445 (28%), Positives = 156/445 (35%), Gaps = 102/445 (22%)
Query: 215 GCHPTHGRCDRPGD--CDCRPGWRGELCSQ-CQPYPGCK--HGYCNGSSWDCTCDTN--- 266
GC H + PG C+C+PG+R S+ C C +G C T +
Sbjct: 66 GCQ--HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 123
Query: 267 -WGGILCDQDLNYCGTHEPC-QHGGTCEN---TAPDQYFCRCAEGF----SGVDCERVDN 317
G +D +C PC G+C + C C G+ G CE VD
Sbjct: 124 CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE 183
Query: 318 PCAP--QPCAHGTCSLAGTTRGFTCTCDRGW--GG--------XXXXXXXXXXASGPCLH 365
CA CAHG + G+ F C C G+ G +G C H
Sbjct: 184 -CAAGLAQCAHGCLNTQGS---FKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 239
Query: 366 GASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
G C G C C G+ T DVD+C A PC C N GGY
Sbjct: 240 G--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--------ADSPCCQ-QVCTNNPGGY 288
Query: 423 SCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRT 471
C C AG+ G CE +VD+C G C H C +L F C+C AGY R
Sbjct: 289 ECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRG 345
Query: 472 CS------LDVDDCAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH------- 516
CS +D+D P RP + D L VG E +H
Sbjct: 346 CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFV 405
Query: 517 CA----GSPCG-------NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLV 563
C G C NG C C C GWTG C + D K CS
Sbjct: 406 CLDDSFGHDCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSF-- 461
Query: 564 EESERCAEGMCANGGTCVREEGSWR 588
C+ C NGGTC G+ R
Sbjct: 462 ----SCS---CQNGGTCDSVTGACR 479
Score = 64.9 bits (151), Expect = 1e-09
Identities = 79/282 (28%), Positives = 99/282 (35%), Gaps = 48/282 (17%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDV--DDC 479
CL G DC DDC +G TC+ +D C C G+ G TC D +C
Sbjct: 406 CLDDSFGHDCSLTCDDCR----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNC 459
Query: 480 A-PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD------RDHCAGS-PCGNGAACYTA 531
+ C NGG C + A C CP G SGTNCED HC C N C+
Sbjct: 460 SFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 517
Query: 532 QSDYYCHCAPGWTGKNCTQR------AARDRKTCSVLVEESERC--AEGMCA-NGGTCVR 582
C C PG G+ C + C + ++ C +G C+ G R
Sbjct: 518 YG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG--FR 573
Query: 583 EEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG--CREGRT 640
E + + G C P+ G CG C G
Sbjct: 574 GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRC-PAGF-QGEDCGQECPVGTF 631
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G C S CG +PC G +G C C G TGE C
Sbjct: 632 GVNCSSSCS-CGGAPCH------GVTG--QCRCPPGRTGEDC 664
Score = 61.7 bits (143), Expect = 1e-08
Identities = 73/268 (27%), Positives = 101/268 (37%), Gaps = 47/268 (17%)
Query: 434 DCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN 486
D +VD+C G C H C++ + C C G+ RTC L ++ CA N
Sbjct: 52 DQRPDVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCA---LGN 105
Query: 487 GG---ECVDL-LNAYRCICPVGFSGTNCEDDRDHCAG-SPCGN--GAA---CYTAQSDYY 536
GG CV L + +RC C GF ++D HC SPC N G+ C +
Sbjct: 106 GGCQHHCVQLTITRHRCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 162
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXX 594
C C G+ + A D K C E+ + CA G+ CA+G C+ +GS++
Sbjct: 163 CECHVGY-------QLAADGKAC----EDVDECAAGLAQCAHG--CLNTQGSFKCVCHAG 209
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLP--SALPPGWACGCREG---RTGALCELSLD 649
G C S G C C G T + +D
Sbjct: 210 YELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGW 677
C SPC C G + C C AG+
Sbjct: 270 DCADSPCCQ-QVCTNNPGGYECGCYAGY 296
Score = 56.8 bits (131), Expect = 4e-07
Identities = 81/309 (26%), Positives = 106/309 (34%), Gaps = 50/309 (16%)
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT---G 444
DVDEC + G C + C NT G Y C C G+ R C ++ C G
Sbjct: 56 DVDECRTHN------GGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLA-INSCALGNG 106
Query: 445 QCLHGATCIDLVDDFH-CACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C H C+ L H C C G+ GR C + CA R + C + RC
Sbjct: 107 GCQHH--CVQLTITRHRCQCRPGFQLQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARC 163
Query: 500 ICPVGFS----GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
C VG+ G CED + AG + C +G C Q + C C G+ + A
Sbjct: 164 ECHVGYQLAADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGY------ELGAD 215
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
R+ + +E C AN G C G
Sbjct: 216 GRQCYRIEMEIVNSCE----ANNGGC--SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 615 XXQAGGTCLPSAL--PPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGW 668
C P G+ CGC G G CE +D C SS C +G
Sbjct: 270 DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGS 328
Query: 669 WMCECVAGW 677
+ C C AG+
Sbjct: 329 FQCSCEAGY 337
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
+G C H C + + CEC G+ D C + G C + T
Sbjct: 64 NGGCQH--RCVNTPGSYLCECKPGFR---LHTDSRTCLAINSCALGNGGCQHHCV-QLTI 117
Query: 420 GGYSCACLAGWT----GRDC--ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA----G 469
+ C C G+ GR C + + G C+H C + C C GY G
Sbjct: 118 TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADG 175
Query: 470 RTCSLDVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNC----EDDRDHCAG 519
+ C DVD+CA C +G C++ +++C+C G+ G C + + C
Sbjct: 176 KACE-DVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 232
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ G C + C C G+ + QR D C+ C + +C N
Sbjct: 233 NNGGCSHGCSHTSAGPLCTCPRGYE-LDTDQRTCIDVDDCA-----DSPCCQQVCTN 283
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 136 bits (328), Expect = 5e-31
Identities = 155/563 (27%), Positives = 200/563 (35%), Gaps = 96/563 (17%)
Query: 194 GDKHCLPGWQGDNCEKPV--------CKEGCHPTH--GRCD-RPGDCDCRPGWRGELCSQ 242
G C PG G++CE C+E C RCD G C C PG+ G C
Sbjct: 651 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD 710
Query: 243 CQPY----PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
P P C+ G+C+ ++ C+C W G C + + C H C
Sbjct: 711 VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC 770
Query: 292 E--NTAPDQY--FCRCAEGFSGVDCERV-----DNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+ + D C C G+ G CE+ P Q C + G CTC
Sbjct: 771 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG-ACTC 829
Query: 343 DRGWGGXXXXXXXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
GW G G C GA+C D ++G +C C G GP CAE +
Sbjct: 830 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAE---K 884
Query: 396 CSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV------DDCTGQCL 447
C R + G G C+N C+ G C C AGWTG C++ + C +C
Sbjct: 885 CLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 942
Query: 448 --HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP-------CTNGGECVDLLNAYR 498
GA C + C C G+ G C P C NGG C A
Sbjct: 943 CPPGAACHHVTG--ACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA-- 998
Query: 499 CICPVGFSGTNCE---------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
C CP GF GT+C + H G CG GAAC C C PG G C
Sbjct: 999 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGT--CLCPPGRAGVRCE 1054
Query: 550 QRAARDRKTCSVLVEESERCAE-GMC-ANGGTCVREEG-SWRXXXXXXXXXXXXDSXXXX 606
+ ++R V E + C G+C A+ G+C G + R +
Sbjct: 1055 RGCPQNR--FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE 1112
Query: 607 XXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNG 659
A GTC P + C R+GA C L P C G
Sbjct: 1113 CSCHNNSTCEPATGTC--RCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGG 1170
Query: 660 GRCVGGSGWWMCECVAGWTGETC 682
C SG C CV G+ G TC
Sbjct: 1171 ADCDPVSG--QCHCVDGYMGPTC 1191
Score = 128 bits (310), Expect = 7e-29
Identities = 168/609 (27%), Positives = 201/609 (33%), Gaps = 93/609 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGC 216
C YY C C + H G C PG G C P C E C
Sbjct: 493 CPKGYYGKHCRKKCNCANRGRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 549
Query: 217 H---PTHGRCD-RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWD-CTCDTNWGGIL 271
P CD R G C C+ G+RGE C Q + C+ GY W CTC G+
Sbjct: 550 QCVQPHTQSCDKRDGSCSCKAGFRGERC-QAE----CELGYFGPGCWQACTCPV---GVA 601
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC--AHGTC 329
CD CG + C G E+ + C G GV+C C PC G C
Sbjct: 602 CDSVSGECG--KRCPAGFQGEDCGQE-----CPVGTFGVNCSS-SCSCGGAPCHGVTGQC 653
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
G C D G A C H A C D G C C G+ G C
Sbjct: 654 RCPPGRTGEDCEADCPEGRWGLGCQEICPA---CQHAARC-DPETG-ACLCLPGFVGSRC 708
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD------DCT 443
+DV + C N C+ G C+C GWTG C+ D DC+
Sbjct: 709 -QDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCS 765
Query: 444 G--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD------CAPR-PCTNGGECVDLL 494
C G D + C C AGY G C C R C +G C +
Sbjct: 766 HPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVS 824
Query: 495 NAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
A C CP G+ GT CE D + C GAAC C C G G
Sbjct: 825 GA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGRRGPR 880
Query: 548 CTQRA-ARD-RKTCSVLVEESERCAE-GMC-ANGGTCVREEGSWRXXXXXX--XXXXXXD 601
C ++ RD R C S C G+C + G C+ G W +
Sbjct: 881 CAEKCLPRDVRAGC----RHSGGCLNGGLCDPHTGRCLCPAG-WTGDKCQSPCLRGWFGE 935
Query: 602 SXXXXXXXXXXXXXXQAGGTCL--PSALPPGWACGCREGRTGALCELSLDLCGSSPCRNG 659
+ G C P G GC GR G CE LCG C NG
Sbjct: 936 ACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCE---QLCG---CLNG 989
Query: 660 GRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPA 719
G C +G C C G+ G C + + T CLC
Sbjct: 990 GSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT-CLC-- 1044
Query: 720 PPQRAARRC 728
PP RA RC
Sbjct: 1045 PPGRAGVRC 1053
Score = 122 bits (295), Expect = 5e-27
Identities = 133/463 (28%), Positives = 169/463 (36%), Gaps = 88/463 (19%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--------PVCKE 214
+C +Y +C T C +D GH C P G C PGW G +C++ P C
Sbjct: 711 VCPAGWYGPSCQTRCSCAND--GH--CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSH 766
Query: 215 GCHPT--HGRCDR-PGDCDCRPGWRGELCSQCQPY----PGCK------HGY-CNGSSWD 260
C+ + HG CD G C C G+ G C Q P PGC+ HG C+ S
Sbjct: 767 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA 826
Query: 261 CTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
CTC W G C+ C + C G C+ C C G G C
Sbjct: 827 CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS---CLCPAGRRGPRCAE 883
Query: 315 VDNPCAPQP----CAH-GTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP----- 362
C P+ C H G C G T C C GW G G
Sbjct: 884 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR 940
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C GA+C H+ G C C G+TG C + E G C+N +C+ G
Sbjct: 941 CSCPPGAACH-HVTG-ACRCPPGFTGSGCEQGCPPGRYGPGCEQLCG-CLNGGSCDAATG 997
Query: 421 GYSCACLAGWTGRDCETNVD------DCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
+C C G+ G DC +CT C GA C + C C G AG C
Sbjct: 998 --ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRC 1053
Query: 473 SLDVDD------CAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCE----DDRDHCA--- 518
C C NGG C N C C +G++G +CE R A
Sbjct: 1054 ERGCPQNRFGVGCEHTCSCRNGGLC-HASNG-SCSCGLGWTGRHCELACPPGRYGAACHL 1111
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
C N + C A C C PG+ G+ C R R TC++
Sbjct: 1112 ECSCHNNSTCEPATGT--CRCGPGFYGQACEHR--RSGATCNL 1150
Score = 107 bits (257), Expect = 2e-22
Identities = 112/390 (28%), Positives = 140/390 (35%), Gaps = 62/390 (15%)
Query: 198 CLPGWQGDNCEKPV--------CKEGCHPTHGR-CDRP-GDCDCRPGWRGELCSQ-CQPY 246
C GW+G CE C+ C+ T G CD G C C G RG C++ C P
Sbjct: 829 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPR 888
Query: 247 P---GCKH-------GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
GC+H G C+ + C C W G C E C +C A
Sbjct: 889 DVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAA 948
Query: 297 DQYF---CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL--AGTTRGFT--CTCDRGWGGX 349
+ CRC GF+G CE+ P P C G+ T C C G+ G
Sbjct: 949 CHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGT 1008
Query: 350 XXXXXXXXXASGP-CLH------GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMT 402
GP C H GA+C D + G TC C G G C +
Sbjct: 1009 DCNLTCPQGRFGPNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGC 1066
Query: 403 EGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCA 462
E C N C+ + G SC+C GWTGR CE G+ +GA C C+
Sbjct: 1067 EHTCS-CRNGGLCHASNG--SCSCGLGWTGRHCELACP--PGR--YGAAC-----HLECS 1114
Query: 463 CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC--ICPVGFSGTNCEDDRDHCAGS 520
C + TC C P G C + C C G G +C HC
Sbjct: 1115 C---HNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSC---TLHC--- 1165
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
CG GA C CHC G+ G C +
Sbjct: 1166 DCGGGADCDPVSGQ--CHCVDGYMGPTCRE 1193
Score = 101 bits (241), Expect = 2e-20
Identities = 107/325 (32%), Positives = 125/325 (38%), Gaps = 64/325 (19%)
Query: 275 DLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCA--PQPCAHG 327
D++ C TH CQH C NT P Y C C GF C + N CA C H
Sbjct: 56 DVDECRTHNGGCQH--RCVNT-PGSYLCECKPGFRLHTDSRTCLAI-NSCALGNGGCQHH 111
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
L T C C G+ G +G C+H C+ CEC
Sbjct: 112 CVQLTITRH--RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHV 167
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRD 434
G+ G AC EDVDEC+ L C A C NT G + C C AG+ GR
Sbjct: 168 GYQLAADGKAC-EDVDECAA------GLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ 218
Query: 435 C---ETN-VDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRP 483
C E V+ C G C HG C C C GY RTC +DVDDCA P
Sbjct: 219 CYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTC-IDVDDCADSP 275
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C C + Y C C G+ G CED D CA S G C + C C
Sbjct: 276 CCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDV-DECASSRGGCEHHCTNLAGSFQCSC 333
Query: 540 APGWTGKNCTQRAARDRKTCSVLVE 564
G+ R DR+ CS L E
Sbjct: 334 EAGY-------RLHEDRRGCSPLEE 351
Score = 96.7 bits (230), Expect = 4e-19
Identities = 97/335 (28%), Positives = 124/335 (37%), Gaps = 58/335 (17%)
Query: 261 CTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C C W G++C++ C CQ+GGTC++ CRC G SG +CE
Sbjct: 435 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA---CRCPPGVSGTNCED 491
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGP-------C 363
C+ A R C CD G G A GP C
Sbjct: 492 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 551
Query: 364 L--HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN--AAACNNTA 419
+ H SC D DG +C C G+ G C EC G C AC++ +
Sbjct: 552 VQPHTQSC-DKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVS 606
Query: 420 GGYSCACLAGWTGRDC--ETNVD----DCTGQC-LHGATCIDLVDDFHCACAAGYAGRTC 472
G C AG+ G DC E V +C+ C GA C + C C G G C
Sbjct: 607 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ--CRCPPGRTGEDC 664
Query: 473 SLDVDD------CAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--- 521
D + C C + C A C+C GF G+ C+D P
Sbjct: 665 EADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQ 722
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
C N C+ A +C CAPGWTG +C QRA
Sbjct: 723 TRCSCANDGHCHPATG--HCSCAPGWTGFSC-QRA 754
Score = 81.0 bits (191), Expect = 2e-14
Identities = 126/445 (28%), Positives = 156/445 (35%), Gaps = 102/445 (22%)
Query: 215 GCHPTHGRCDRPGD--CDCRPGWRGELCSQ-CQPYPGCK--HGYCNGSSWDCTCDTN--- 266
GC H + PG C+C+PG+R S+ C C +G C T +
Sbjct: 66 GCQ--HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 123
Query: 267 -WGGILCDQDLNYCGTHEPC-QHGGTCEN---TAPDQYFCRCAEGF----SGVDCERVDN 317
G +D +C PC G+C + C C G+ G CE VD
Sbjct: 124 CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE 183
Query: 318 PCAP--QPCAHGTCSLAGTTRGFTCTCDRGW--GG--------XXXXXXXXXXASGPCLH 365
CA CAHG + G+ F C C G+ G +G C H
Sbjct: 184 -CAAGLAQCAHGCLNTQGS---FKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 239
Query: 366 GASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
G C G C C G+ T DVD+C A PC C N GGY
Sbjct: 240 G--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--------ADSPCCQ-QVCTNNPGGY 288
Query: 423 SCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRT 471
C C AG+ G CE +VD+C G C H C +L F C+C AGY R
Sbjct: 289 ECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRG 345
Query: 472 CS------LDVDDCAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH------- 516
CS +D+D P RP + D L VG E +H
Sbjct: 346 CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFV 405
Query: 517 CA----GSPCG-------NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLV 563
C G C NG C C C GWTG C + D K CS
Sbjct: 406 CLDDSFGHDCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSF-- 461
Query: 564 EESERCAEGMCANGGTCVREEGSWR 588
C+ C NGGTC G+ R
Sbjct: 462 ----SCS---CQNGGTCDSVTGACR 479
Score = 64.9 bits (151), Expect = 1e-09
Identities = 79/282 (28%), Positives = 99/282 (35%), Gaps = 48/282 (17%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDV--DDC 479
CL G DC DDC +G TC+ +D C C G+ G TC D +C
Sbjct: 406 CLDDSFGHDCSLTCDDCR----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNC 459
Query: 480 A-PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD------RDHCAGS-PCGNGAACYTA 531
+ C NGG C + A C CP G SGTNCED HC C N C+
Sbjct: 460 SFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 517
Query: 532 QSDYYCHCAPGWTGKNCTQR------AARDRKTCSVLVEESERC--AEGMCA-NGGTCVR 582
C C PG G+ C + C + ++ C +G C+ G R
Sbjct: 518 YG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG--FR 573
Query: 583 EEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG--CREGRT 640
E + + G C P+ G CG C G
Sbjct: 574 GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRC-PAGF-QGEDCGQECPVGTF 631
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G C S CG +PC G +G C C G TGE C
Sbjct: 632 GVNCSSSCS-CGGAPCH------GVTG--QCRCPPGRTGEDC 664
Score = 61.7 bits (143), Expect = 1e-08
Identities = 73/268 (27%), Positives = 101/268 (37%), Gaps = 47/268 (17%)
Query: 434 DCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN 486
D +VD+C G C H C++ + C C G+ RTC L ++ CA N
Sbjct: 52 DQRPDVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCA---LGN 105
Query: 487 GG---ECVDL-LNAYRCICPVGFSGTNCEDDRDHCAG-SPCGN--GAA---CYTAQSDYY 536
GG CV L + +RC C GF ++D HC SPC N G+ C +
Sbjct: 106 GGCQHHCVQLTITRHRCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 162
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXX 594
C C G+ + A D K C E+ + CA G+ CA+G C+ +GS++
Sbjct: 163 CECHVGY-------QLAADGKAC----EDVDECAAGLAQCAHG--CLNTQGSFKCVCHAG 209
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLP--SALPPGWACGCREG---RTGALCELSLD 649
G C S G C C G T + +D
Sbjct: 210 YELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGW 677
C SPC C G + C C AG+
Sbjct: 270 DCADSPCCQ-QVCTNNPGGYECGCYAGY 296
Score = 56.8 bits (131), Expect = 4e-07
Identities = 81/309 (26%), Positives = 106/309 (34%), Gaps = 50/309 (16%)
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT---G 444
DVDEC + G C + C NT G Y C C G+ R C ++ C G
Sbjct: 56 DVDECRTHN------GGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLA-INSCALGNG 106
Query: 445 QCLHGATCIDLVDDFH-CACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C H C+ L H C C G+ GR C + CA R + C + RC
Sbjct: 107 GCQHH--CVQLTITRHRCQCRPGFQLQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARC 163
Query: 500 ICPVGFS----GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
C VG+ G CED + AG + C +G C Q + C C G+ + A
Sbjct: 164 ECHVGYQLAADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGY------ELGAD 215
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
R+ + +E C AN G C G
Sbjct: 216 GRQCYRIEMEIVNSCE----ANNGGC--SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 269
Query: 615 XXQAGGTCLPSAL--PPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGW 668
C P G+ CGC G G CE +D C SS C +G
Sbjct: 270 DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGS 328
Query: 669 WMCECVAGW 677
+ C C AG+
Sbjct: 329 FQCSCEAGY 337
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
+G C H C + + CEC G+ D C + G C + T
Sbjct: 64 NGGCQH--RCVNTPGSYLCECKPGFR---LHTDSRTCLAINSCALGNGGCQHHCV-QLTI 117
Query: 420 GGYSCACLAGWT----GRDC--ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA----G 469
+ C C G+ GR C + + G C+H C + C C GY G
Sbjct: 118 TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADG 175
Query: 470 RTCSLDVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNC----EDDRDHCAG 519
+ C DVD+CA C +G C++ +++C+C G+ G C + + C
Sbjct: 176 KACE-DVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 232
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ G C + C C G+ + QR D C+ C + +C N
Sbjct: 233 NNGGCSHGCSHTSAGPLCTCPRGYE-LDTDQRTCIDVDDCA-----DSPCCQQVCTN 283
>X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.
Length = 2201
Score = 135 bits (326), Expect = 8e-31
Identities = 141/508 (27%), Positives = 181/508 (35%), Gaps = 84/508 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCK-HGYC-N 255
C PGW+G NC +P C CH GRC G C C G+ GE CSQ C G C N
Sbjct: 176 CEPGWKGPNCSEPECPGNCH-LRGRC-IDGQCICDDGFTGEDCSQLACPSDCNDQGKCVN 233
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPC-QHGGTCENTAPDQYFCRCAEGFSGVDCER 314
G C C + G C +++ C PC + GTC + C C +GF+G DC +
Sbjct: 234 GV---CICFEGYAGADCSREI--CPV--PCSEEHGTCVDG-----LCVCHDGFAGDDCNK 281
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
P C G C CD G+ G C C ++
Sbjct: 282 --------PLCLNNCYNRGRCVENECVCDEGFTG---EDCSELICPNDCFDRGRC---IN 327
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCV--------------NAAACNNT 418
G TC C +G+TG C + C T+G G CV A C+N
Sbjct: 328 G-TCYCEEGFTGEDCGKPT--CPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNR 384
Query: 419 AGGYS--CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C G+TG DC C C C+ + C C GY G CS
Sbjct: 385 GRCVDGRCECDDGFTGADC--GELKCPNGCSGHGRCV----NGQCVCDEGYTGEDCS--- 435
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
P C + G CV+ +C+C GF G +C D + C C
Sbjct: 436 QLRCPNDCHSRGRCVE----GKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM---- 484
Query: 537 CHCAPGWTGKNCTQR-AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G+TG++C R RD + V+ C +G G C E S
Sbjct: 485 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF--TGPDCA--ELSCPNDCHGQG 540
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ C C C EG TG C C S
Sbjct: 541 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC--GQHSC-PSD 597
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G+CV G C C G++GE C+
Sbjct: 598 CNNLGQCVSG----RCICNEGYSGEDCS 621
Score = 127 bits (306), Expect = 2e-28
Identities = 140/499 (28%), Positives = 183/499 (36%), Gaps = 86/499 (17%)
Query: 190 CTPDGDKHCLPGWQGDNCEKPVCK-EGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPG 248
CT G CL G +P C G T G C C C PGW+G CS+ + PG
Sbjct: 140 CTA-GAGCCLQPATGRLDTRPFCSGRGNFSTEG-CG----CVCEPGWKGPNCSEPE-CPG 192
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS 308
H C CD + G +D + C G C N C C EG++
Sbjct: 193 NCHLRGRCIDGQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYA 243
Query: 309 GVDCERVDNPCAPQPCA--HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G DC R P PC+ HGTC + G C C G+ G CL+
Sbjct: 244 GADCSR---EICPVPCSEEHGTC-VDG-----LCVCHDGFAGDDCNKPL-------CLNN 287
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV--DECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
R C C +G+TG C+E + ++C R G C+N +C
Sbjct: 288 CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR-------GRCING----------TC 330
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
C G+TG DC C C C ++ C C G+AG CS + P C
Sbjct: 331 YCEEGFTGEDC--GKPTCPHACHTQGRC----EEGQCVCDEGFAGLDCS---EKRCPADC 381
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
N G CVD RC C GF+G +C + + C G+G C Q C C G+T
Sbjct: 382 HNRGRCVD----GRCECDDGFTGADCGELK--CPNGCSGHG-RCVNGQ----CVCDEGYT 430
Query: 545 GKNCTQ-RAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C+Q R D + VE C +G G C + S
Sbjct: 431 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGF--KGYDC--SDMSCPNDCHQHGRCVNGMCV 486
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q C L C C +G TG C +L + C GRCV
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---AELSCPNDCHGQGRCV 543
Query: 664 GGSGWWMCECVAGWTGETC 682
G C C G+ G+ C
Sbjct: 544 NG----QCVCHEGFMGKDC 558
Score = 126 bits (304), Expect = 4e-28
Identities = 113/413 (27%), Positives = 165/413 (39%), Gaps = 76/413 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C + C+ P +D F C +G +C G+ G++C KP C CH T GRC
Sbjct: 300 VCDEGFTGEDCSELICP-NDCFDRGRCI-NGTCYCEEGFTGEDCGKPTCPHACH-TQGRC 356
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGILCDQDL--NYCG 280
+ G C C G+ G CS+ + C + G C C CD + G C + N C
Sbjct: 357 EE-GQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGR--CECDDGFTGADCGELKCPNGCS 413
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFT 339
H C +G C C EG++G DC ++ P C + G C G
Sbjct: 414 GHGRCVNGQ-----------CVCDEGYTGEDCSQLR---CPNDCHSRGRC-----VEG-K 453
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECS 397
C C++G+ G C C ++G C C DG+TG C + +CS
Sbjct: 454 CVCEQGFKGYDCSDMS---CPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRDCS 506
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R G CV+ C C G+TG DC C C C++
Sbjct: 507 NR-------GLCVDG----------QCVCEDGFTGPDCAEL--SCPNDCHGQGRCVN--- 544
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
C C G+ G+ C + P C G CVD +CIC GF+G +C H
Sbjct: 545 -GQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVD----GQCICHEGFTGLDCGQ---HS 593
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
S C N C + + C C G++G++C++ + + + EE+ A
Sbjct: 594 CPSDCNNLGQCVSGR----CICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLA 642
Score = 124 bits (299), Expect = 2e-27
Identities = 118/415 (28%), Positives = 160/415 (38%), Gaps = 77/415 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+ P H +C DG C G+ GD+C KP+C C+ GRC
Sbjct: 237 ICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCY-NRGRC 294
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGC-KHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+C C G+ GE CS+ C G C NG+ C C+ + G C + C
Sbjct: 295 VE-NECVCDEGFTGEDCSELICPNDCFDRGRCINGT---CYCEEGFTGEDCGKPT--C-- 346
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
C G CE C C EGF+G+DC + C P C + + G C
Sbjct: 347 PHACHTQGRCEEGQ-----CVCDEGFAGLDCS--EKRC-PADCHNRGRCVDG-----RCE 393
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE--DVDECSGR 399
CD G+ G C +G S C C +G+TG C++ ++C R
Sbjct: 394 CDDGFTGADCGEL-------KCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSR 446
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV C C G+ G DC C C C++ +
Sbjct: 447 -------GRCVEG----------KCVCEQGFKGYDCSDM--SCPNDCHQHGRCVNGM--- 484
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C GY G C D PR C+N G CVD +C+C GF+G +C + C
Sbjct: 485 -CVCDDGYTGEDCR---DRQCPRDCSNRGLCVD----GQCVCEDGFTGPDCAE--LSCPN 534
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
G G C Q C C G+ GK+C + + C RC +G C
Sbjct: 535 DCHGQG-RCVNGQ----CVCHEGFMGKDCKE------QRCPSDCHGQGRCVDGQC 578
Score = 85.4 bits (202), Expect = 9e-16
Identities = 94/388 (24%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C G+ G +C + P G C L G C CD G+ G
Sbjct: 174 CVCEPGWKGPNCSEPECP--------GNCHLRGRCIDGQCICDDGFTGEDCSQLA---CP 222
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C C ++G C C +G+ G C+ ++ C E G CV+
Sbjct: 223 SDCNDQGKC---VNG-VCICFEGYAGADCSREI--CPVPCSEEH--GTCVDGL------- 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G+ G DC N C C + C++ C C G+ G CS +
Sbjct: 268 ---CVCHDGFAGDDC--NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELIC 315
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
P C + G C++ C C GF+G +C + C + C C Q C C
Sbjct: 316 PNDCFDRGRCIN----GTCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEEGQ----CVCD 364
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXX 599
G+ G +C++ K C RC +G C + G + G +
Sbjct: 365 EGFAGLDCSE------KRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
Query: 600 XDSXXXXXXXXXXXXXXQ--AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ Q C C C +G G C D+ + C
Sbjct: 419 VNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCH 475
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVR 685
GRCV G MC C G+TGE C R
Sbjct: 476 QHGRCVNG----MCVCDDGYTGEDCRDR 499
>M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.
Length = 2203
Score = 135 bits (326), Expect = 8e-31
Identities = 141/508 (27%), Positives = 181/508 (35%), Gaps = 84/508 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCK-HGYC-N 255
C PGW+G NC +P C CH GRC G C C G+ GE CSQ C G C N
Sbjct: 176 CEPGWKGPNCSEPECPGNCH-LRGRC-IDGQCICDDGFTGEDCSQLACPSDCNDQGKCVN 233
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPC-QHGGTCENTAPDQYFCRCAEGFSGVDCER 314
G C C + G C +++ C PC + GTC + C C +GF+G DC +
Sbjct: 234 GV---CICFEGYAGADCSREI--CPV--PCSEEHGTCVDG-----LCVCHDGFAGDDCNK 281
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
P C G C CD G+ G C C ++
Sbjct: 282 --------PLCLNNCYNRGRCVENECVCDEGFTG---EDCSELICPNDCFDRGRC---IN 327
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCV--------------NAAACNNT 418
G TC C +G+TG C + C T+G G CV A C+N
Sbjct: 328 G-TCYCEEGFTGEDCGKPT--CPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNR 384
Query: 419 AGGYS--CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C G+TG DC C C C+ + C C GY G CS
Sbjct: 385 GRCVDGRCECDDGFTGADC--GELKCPNGCSGHGRCV----NGQCVCDEGYTGEDCS--- 435
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
P C + G CV+ +C+C GF G +C D + C C
Sbjct: 436 QLRCPNDCHSRGRCVE----GKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM---- 484
Query: 537 CHCAPGWTGKNCTQR-AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G+TG++C R RD + V+ C +G G C E S
Sbjct: 485 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF--TGPDCA--ELSCPNDCHGRG 540
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ C C C EG TG C C S
Sbjct: 541 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC--GQHSC-PSD 597
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G+CV G C C G++GE C+
Sbjct: 598 CNNLGQCVSG----RCICNEGYSGEDCS 621
Score = 127 bits (306), Expect = 2e-28
Identities = 140/499 (28%), Positives = 183/499 (36%), Gaps = 86/499 (17%)
Query: 190 CTPDGDKHCLPGWQGDNCEKPVCK-EGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPG 248
CT G CL G +P C G T G C C C PGW+G CS+ + PG
Sbjct: 140 CTA-GAGCCLQPATGRLDTRPFCSGRGNFSTEG-CG----CVCEPGWKGPNCSEPE-CPG 192
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS 308
H C CD + G +D + C G C N C C EG++
Sbjct: 193 NCHLRGRCIDGQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYA 243
Query: 309 GVDCERVDNPCAPQPCA--HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G DC R P PC+ HGTC + G C C G+ G CL+
Sbjct: 244 GADCSR---EICPVPCSEEHGTC-VDG-----LCVCHDGFAGDDCNKPL-------CLNN 287
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV--DECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
R C C +G+TG C+E + ++C R G C+N +C
Sbjct: 288 CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR-------GRCING----------TC 330
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
C G+TG DC C C C ++ C C G+AG CS + P C
Sbjct: 331 YCEEGFTGEDC--GKPTCPHACHTQGRC----EEGQCVCDEGFAGLDCS---EKRCPADC 381
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
N G CVD RC C GF+G +C + + C G+G C Q C C G+T
Sbjct: 382 HNRGRCVD----GRCECDDGFTGADCGELK--CPNGCSGHG-RCVNGQ----CVCDEGYT 430
Query: 545 GKNCTQ-RAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C+Q R D + VE C +G G C + S
Sbjct: 431 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGF--KGYDC--SDMSCPNDCHQHGRCVNGMCV 486
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q C L C C +G TG C +L + C GRCV
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---AELSCPNDCHGRGRCV 543
Query: 664 GGSGWWMCECVAGWTGETC 682
G C C G+ G+ C
Sbjct: 544 NG----QCVCHEGFMGKDC 558
Score = 126 bits (304), Expect = 4e-28
Identities = 113/413 (27%), Positives = 165/413 (39%), Gaps = 76/413 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C + C+ P +D F C +G +C G+ G++C KP C CH T GRC
Sbjct: 300 VCDEGFTGEDCSELICP-NDCFDRGRCI-NGTCYCEEGFTGEDCGKPTCPHACH-TQGRC 356
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGILCDQDL--NYCG 280
+ G C C G+ G CS+ + C + G C C CD + G C + N C
Sbjct: 357 EE-GQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGR--CECDDGFTGADCGELKCPNGCS 413
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFT 339
H C +G C C EG++G DC ++ P C + G C G
Sbjct: 414 GHGRCVNGQ-----------CVCDEGYTGEDCSQLR---CPNDCHSRGRC-----VEG-K 453
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECS 397
C C++G+ G C C ++G C C DG+TG C + +CS
Sbjct: 454 CVCEQGFKGYDCSDMS---CPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRDCS 506
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R G CV+ C C G+TG DC C C C++
Sbjct: 507 NR-------GLCVDG----------QCVCEDGFTGPDCAEL--SCPNDCHGRGRCVN--- 544
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
C C G+ G+ C + P C G CVD +CIC GF+G +C H
Sbjct: 545 -GQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVD----GQCICHEGFTGLDCGQ---HS 593
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
S C N C + + C C G++G++C++ + + + EE+ A
Sbjct: 594 CPSDCNNLGQCVSGR----CICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLA 642
Score = 124 bits (299), Expect = 2e-27
Identities = 118/415 (28%), Positives = 160/415 (38%), Gaps = 77/415 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+ P H +C DG C G+ GD+C KP+C C+ GRC
Sbjct: 237 ICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCY-NRGRC 294
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGC-KHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+C C G+ GE CS+ C G C NG+ C C+ + G C + C
Sbjct: 295 VE-NECVCDEGFTGEDCSELICPNDCFDRGRCINGT---CYCEEGFTGEDCGKPT--C-- 346
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
C G CE C C EGF+G+DC + C P C + + G C
Sbjct: 347 PHACHTQGRCEEGQ-----CVCDEGFAGLDCS--EKRC-PADCHNRGRCVDG-----RCE 393
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE--DVDECSGR 399
CD G+ G C +G S C C +G+TG C++ ++C R
Sbjct: 394 CDDGFTGADCGEL-------KCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSR 446
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV C C G+ G DC C C C++ +
Sbjct: 447 -------GRCVEG----------KCVCEQGFKGYDCSDM--SCPNDCHQHGRCVNGM--- 484
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C GY G C D PR C+N G CVD +C+C GF+G +C + C
Sbjct: 485 -CVCDDGYTGEDCR---DRQCPRDCSNRGLCVD----GQCVCEDGFTGPDCAE--LSCPN 534
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
G G C Q C C G+ GK+C + + C RC +G C
Sbjct: 535 DCHGRG-RCVNGQ----CVCHEGFMGKDCKE------QRCPSDCHGQGRCVDGQC 578
Score = 85.4 bits (202), Expect = 9e-16
Identities = 94/388 (24%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C G+ G +C + P G C L G C CD G+ G
Sbjct: 174 CVCEPGWKGPNCSEPECP--------GNCHLRGRCIDGQCICDDGFTGEDCSQLA---CP 222
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C C ++G C C +G+ G C+ ++ C E G CV+
Sbjct: 223 SDCNDQGKC---VNG-VCICFEGYAGADCSREI--CPVPCSEEH--GTCVDGL------- 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G+ G DC N C C + C++ C C G+ G CS +
Sbjct: 268 ---CVCHDGFAGDDC--NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELIC 315
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
P C + G C++ C C GF+G +C + C + C C Q C C
Sbjct: 316 PNDCFDRGRCIN----GTCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEEGQ----CVCD 364
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXX 599
G+ G +C++ K C RC +G C + G + G +
Sbjct: 365 EGFAGLDCSE------KRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
Query: 600 XDSXXXXXXXXXXXXXXQ--AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ Q C C C +G G C D+ + C
Sbjct: 419 VNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCH 475
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVR 685
GRCV G MC C G+TGE C R
Sbjct: 476 QHGRCVNG----MCVCDDGYTGEDCRDR 499
>AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachion)
protein.
Length = 2201
Score = 135 bits (326), Expect = 8e-31
Identities = 141/508 (27%), Positives = 181/508 (35%), Gaps = 84/508 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCK-HGYC-N 255
C PGW+G NC +P C CH GRC G C C G+ GE CSQ C G C N
Sbjct: 176 CEPGWKGPNCSEPECPGNCH-LRGRC-IDGQCICDDGFTGEDCSQLACPSDCNDQGKCVN 233
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPC-QHGGTCENTAPDQYFCRCAEGFSGVDCER 314
G C C + G C +++ C PC + GTC + C C +GF+G DC +
Sbjct: 234 GV---CICFEGYAGADCSREI--CPV--PCSEEHGTCVDG-----LCVCHDGFAGDDCNK 281
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
P C G C CD G+ G C C ++
Sbjct: 282 --------PLCLNNCYNRGRCVENECVCDEGFTG---EDCSELICPNDCFDRGRC---IN 327
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCV--------------NAAACNNT 418
G TC C +G+TG C + C T+G G CV A C+N
Sbjct: 328 G-TCYCEEGFTGEDCGKPT--CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNR 384
Query: 419 AGGYS--CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C G+TG DC C C C+ + C C GY G CS
Sbjct: 385 GRCVDGRCECDDGFTGADC--GELKCPNGCSGHGRCV----NGQCVCDEGYTGEDCS--- 435
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
P C + G CV+ +C+C GF G +C D + C C
Sbjct: 436 QLRCPNDCHSRGRCVE----GKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM---- 484
Query: 537 CHCAPGWTGKNCTQR-AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G+TG++C R RD + V+ C +G G C E S
Sbjct: 485 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF--TGPDCA--ELSCPNDCHGQG 540
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ C C C EG TG C C S
Sbjct: 541 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC--GQHSC-PSD 597
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G+CV G C C G++GE C+
Sbjct: 598 CNNLGQCVSG----RCICNEGYSGEDCS 621
Score = 126 bits (305), Expect = 3e-28
Identities = 140/499 (28%), Positives = 183/499 (36%), Gaps = 86/499 (17%)
Query: 190 CTPDGDKHCLPGWQGDNCEKPVCK-EGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPG 248
CT G CL G +P C G T G C C C PGW+G CS+ + PG
Sbjct: 140 CTA-GAGCCLQPATGRLDTRPFCSGRGNFSTEG-CG----CVCEPGWKGPNCSEPE-CPG 192
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS 308
H C CD + G +D + C G C N C C EG++
Sbjct: 193 NCHLRGRCIDGQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYA 243
Query: 309 GVDCERVDNPCAPQPCA--HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G DC R P PC+ HGTC + G C C G+ G CL+
Sbjct: 244 GADCSR---EICPVPCSEEHGTC-VDG-----LCVCHDGFAGDDCNKPL-------CLNN 287
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV--DECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
R C C +G+TG C+E + ++C R G C+N +C
Sbjct: 288 CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR-------GRCING----------TC 330
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
C G+TG DC C C C ++ C C G+AG CS + P C
Sbjct: 331 YCEEGFTGEDC--GKPTCPHACHTQGRC----EEGQCVCDEGFAGVDCS---EKRCPADC 381
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
N G CVD RC C GF+G +C + + C G+G C Q C C G+T
Sbjct: 382 HNRGRCVD----GRCECDDGFTGADCGELK--CPNGCSGHG-RCVNGQ----CVCDEGYT 430
Query: 545 GKNCTQ-RAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C+Q R D + VE C +G G C + S
Sbjct: 431 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGF--KGYDC--SDMSCPNDCHQHGRCVNGMCV 486
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q C L C C +G TG C +L + C GRCV
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---AELSCPNDCHGQGRCV 543
Query: 664 GGSGWWMCECVAGWTGETC 682
G C C G+ G+ C
Sbjct: 544 NG----QCVCHEGFMGKDC 558
Score = 126 bits (305), Expect = 3e-28
Identities = 113/413 (27%), Positives = 165/413 (39%), Gaps = 76/413 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C + C+ P +D F C +G +C G+ G++C KP C CH T GRC
Sbjct: 300 VCDEGFTGEDCSELICP-NDCFDRGRCI-NGTCYCEEGFTGEDCGKPTCPHACH-TQGRC 356
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGILCDQDL--NYCG 280
+ G C C G+ G CS+ + C + G C C CD + G C + N C
Sbjct: 357 EE-GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR--CECDDGFTGADCGELKCPNGCS 413
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFT 339
H C +G C C EG++G DC ++ P C + G C G
Sbjct: 414 GHGRCVNGQ-----------CVCDEGYTGEDCSQLR---CPNDCHSRGRC-----VEG-K 453
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECS 397
C C++G+ G C C ++G C C DG+TG C + +CS
Sbjct: 454 CVCEQGFKGYDCSDMS---CPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRDCS 506
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R G CV+ C C G+TG DC C C C++
Sbjct: 507 NR-------GLCVDG----------QCVCEDGFTGPDCAEL--SCPNDCHGQGRCVN--- 544
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
C C G+ G+ C + P C G CVD +CIC GF+G +C H
Sbjct: 545 -GQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVD----GQCICHEGFTGLDCGQ---HS 593
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
S C N C + + C C G++G++C++ + + + EE+ A
Sbjct: 594 CPSDCNNLGQCVSGR----CICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLA 642
Score = 125 bits (302), Expect = 7e-28
Identities = 119/415 (28%), Positives = 160/415 (38%), Gaps = 77/415 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+ P H +C DG C G+ GD+C KP+C C+ GRC
Sbjct: 237 ICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCY-NRGRC 294
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGC-KHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+C C G+ GE CS+ C G C NG+ C C+ + G C + C
Sbjct: 295 VE-NECVCDEGFTGEDCSELICPNDCFDRGRCINGT---CYCEEGFTGEDCGKPT--C-- 346
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
C G CE C C EGF+GVDC + C P C + + G C
Sbjct: 347 PHACHTQGRCEEGQ-----CVCDEGFAGVDCS--EKRC-PADCHNRGRCVDG-----RCE 393
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE--DVDECSGR 399
CD G+ G C +G S C C +G+TG C++ ++C R
Sbjct: 394 CDDGFTGADCGEL-------KCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSR 446
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV C C G+ G DC C C C++ +
Sbjct: 447 -------GRCVEG----------KCVCEQGFKGYDCSDM--SCPNDCHQHGRCVNGM--- 484
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C GY G C D PR C+N G CVD +C+C GF+G +C + C
Sbjct: 485 -CVCDDGYTGEDCR---DRQCPRDCSNRGLCVD----GQCVCEDGFTGPDCAE--LSCPN 534
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
G G C Q C C G+ GK+C + + C RC +G C
Sbjct: 535 DCHGQG-RCVNGQ----CVCHEGFMGKDCKE------QRCPSDCHGQGRCVDGQC 578
Score = 85.4 bits (202), Expect = 9e-16
Identities = 94/388 (24%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C G+ G +C + P G C L G C CD G+ G
Sbjct: 174 CVCEPGWKGPNCSEPECP--------GNCHLRGRCIDGQCICDDGFTGEDCSQLA---CP 222
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C C ++G C C +G+ G C+ ++ C E G CV+
Sbjct: 223 SDCNDQGKC---VNG-VCICFEGYAGADCSREI--CPVPCSEEH--GTCVDGL------- 267
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G+ G DC N C C + C++ C C G+ G CS +
Sbjct: 268 ---CVCHDGFAGDDC--NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELIC 315
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
P C + G C++ C C GF+G +C + C + C C Q C C
Sbjct: 316 PNDCFDRGRCIN----GTCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEEGQ----CVCD 364
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXX 599
G+ G +C++ K C RC +G C + G + G +
Sbjct: 365 EGFAGVDCSE------KRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
Query: 600 XDSXXXXXXXXXXXXXXQ--AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ Q C C C +G G C D+ + C
Sbjct: 419 VNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCH 475
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVR 685
GRCV G MC C G+TGE C R
Sbjct: 476 QHGRCVNG----MCVCDDGYTGEDCRDR 499
>AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein
protein.
Length = 2233
Score = 135 bits (326), Expect = 8e-31
Identities = 141/508 (27%), Positives = 181/508 (35%), Gaps = 84/508 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCK-HGYC-N 255
C PGW+G NC +P C CH GRC G C C G+ GE CSQ C G C N
Sbjct: 208 CEPGWKGPNCSEPECPGNCH-LRGRC-IDGQCICDDGFTGEDCSQLACPSDCNDQGKCVN 265
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPC-QHGGTCENTAPDQYFCRCAEGFSGVDCER 314
G C C + G C +++ C PC + GTC + C C +GF+G DC +
Sbjct: 266 GV---CICFEGYAGADCSREI--CPV--PCSEEHGTCVDG-----LCVCHDGFAGDDCNK 313
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
P C G C CD G+ G C C ++
Sbjct: 314 --------PLCLNNCYNRGRCVENECVCDEGFTG---EDCSELICPNDCFDRGRC---IN 359
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCV--------------NAAACNNT 418
G TC C +G+TG C + C T+G G CV A C+N
Sbjct: 360 G-TCYCEEGFTGEDCGKPT--CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNR 416
Query: 419 AGGYS--CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C G+TG DC C C C+ + C C GY G CS
Sbjct: 417 GRCVDGRCECDDGFTGADC--GELKCPNGCSGHGRCV----NGQCVCDEGYTGEDCS--- 467
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
P C + G CV+ +C+C GF G +C D + C C
Sbjct: 468 QLRCPNDCHSRGRCVE----GKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM---- 516
Query: 537 CHCAPGWTGKNCTQR-AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G+TG++C R RD + V+ C +G G C E S
Sbjct: 517 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF--TGPDCA--ELSCPNDCHGRG 572
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ C C C EG TG C C S
Sbjct: 573 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC--GQHSC-PSD 629
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G+CV G C C G++GE C+
Sbjct: 630 CNNLGQCVSG----RCICNEGYSGEDCS 653
Score = 126 bits (305), Expect = 3e-28
Identities = 140/499 (28%), Positives = 183/499 (36%), Gaps = 86/499 (17%)
Query: 190 CTPDGDKHCLPGWQGDNCEKPVCK-EGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPG 248
CT G CL G +P C G T G C C C PGW+G CS+ + PG
Sbjct: 172 CTA-GAGCCLQPATGRLDTRPFCSGRGNFSTEG-CG----CVCEPGWKGPNCSEPE-CPG 224
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS 308
H C CD + G +D + C G C N C C EG++
Sbjct: 225 NCHLRGRCIDGQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYA 275
Query: 309 GVDCERVDNPCAPQPCA--HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
G DC R P PC+ HGTC + G C C G+ G CL+
Sbjct: 276 GADCSR---EICPVPCSEEHGTC-VDG-----LCVCHDGFAGDDCNKPL-------CLNN 319
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV--DECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
R C C +G+TG C+E + ++C R G C+N +C
Sbjct: 320 CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR-------GRCING----------TC 362
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
C G+TG DC C C C ++ C C G+AG CS + P C
Sbjct: 363 YCEEGFTGEDC--GKPTCPHACHTQGRC----EEGQCVCDEGFAGVDCS---EKRCPADC 413
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
N G CVD RC C GF+G +C + + C G+G C Q C C G+T
Sbjct: 414 HNRGRCVD----GRCECDDGFTGADCGELK--CPNGCSGHG-RCVNGQ----CVCDEGYT 462
Query: 545 GKNCTQ-RAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C+Q R D + VE C +G G C + S
Sbjct: 463 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGF--KGYDC--SDMSCPNDCHQHGRCVNGMCV 518
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q C L C C +G TG C +L + C GRCV
Sbjct: 519 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---AELSCPNDCHGRGRCV 575
Query: 664 GGSGWWMCECVAGWTGETC 682
G C C G+ G+ C
Sbjct: 576 NG----QCVCHEGFMGKDC 590
Score = 126 bits (305), Expect = 3e-28
Identities = 113/413 (27%), Positives = 165/413 (39%), Gaps = 76/413 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C + C+ P +D F C +G +C G+ G++C KP C CH T GRC
Sbjct: 332 VCDEGFTGEDCSELICP-NDCFDRGRCI-NGTCYCEEGFTGEDCGKPTCPHACH-TQGRC 388
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGILCDQDL--NYCG 280
+ G C C G+ G CS+ + C + G C C CD + G C + N C
Sbjct: 389 EE-GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR--CECDDGFTGADCGELKCPNGCS 445
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFT 339
H C +G C C EG++G DC ++ P C + G C G
Sbjct: 446 GHGRCVNGQ-----------CVCDEGYTGEDCSQLR---CPNDCHSRGRC-----VEG-K 485
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECS 397
C C++G+ G C C ++G C C DG+TG C + +CS
Sbjct: 486 CVCEQGFKGYDCSDMS---CPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRDCS 538
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R G CV+ C C G+TG DC C C C++
Sbjct: 539 NR-------GLCVDG----------QCVCEDGFTGPDCAEL--SCPNDCHGRGRCVN--- 576
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
C C G+ G+ C + P C G CVD +CIC GF+G +C H
Sbjct: 577 -GQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVD----GQCICHEGFTGLDCGQ---HS 625
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
S C N C + + C C G++G++C++ + + + EE+ A
Sbjct: 626 CPSDCNNLGQCVSGR----CICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLA 674
Score = 125 bits (302), Expect = 7e-28
Identities = 119/415 (28%), Positives = 160/415 (38%), Gaps = 77/415 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C Y C+ P H +C DG C G+ GD+C KP+C C+ GRC
Sbjct: 269 ICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCY-NRGRC 326
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGC-KHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGT 281
+C C G+ GE CS+ C G C NG+ C C+ + G C + C
Sbjct: 327 VE-NECVCDEGFTGEDCSELICPNDCFDRGRCINGT---CYCEEGFTGEDCGKPT--C-- 378
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT 341
C G CE C C EGF+GVDC + C P C + + G C
Sbjct: 379 PHACHTQGRCEEGQ-----CVCDEGFAGVDCS--EKRC-PADCHNRGRCVDG-----RCE 425
Query: 342 CDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE--DVDECSGR 399
CD G+ G C +G S C C +G+TG C++ ++C R
Sbjct: 426 CDDGFTGADCGEL-------KCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSR 478
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDF 459
G CV C C G+ G DC C C C++ +
Sbjct: 479 -------GRCVEG----------KCVCEQGFKGYDCSDM--SCPNDCHQHGRCVNGM--- 516
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
C C GY G C D PR C+N G CVD +C+C GF+G +C + C
Sbjct: 517 -CVCDDGYTGEDCR---DRQCPRDCSNRGLCVD----GQCVCEDGFTGPDCAE--LSCPN 566
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
G G C Q C C G+ GK+C + + C RC +G C
Sbjct: 567 DCHGRG-RCVNGQ----CVCHEGFMGKDCKE------QRCPSDCHGQGRCVDGQC 610
Score = 85.4 bits (202), Expect = 9e-16
Identities = 94/388 (24%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C G+ G +C + P G C L G C CD G+ G
Sbjct: 206 CVCEPGWKGPNCSEPECP--------GNCHLRGRCIDGQCICDDGFTGEDCSQLA---CP 254
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C C ++G C C +G+ G C+ ++ C E G CV+
Sbjct: 255 SDCNDQGKC---VNG-VCICFEGYAGADCSREI--CPVPCSEEH--GTCVDGL------- 299
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G+ G DC N C C + C++ C C G+ G CS +
Sbjct: 300 ---CVCHDGFAGDDC--NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELIC 347
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
P C + G C++ C C GF+G +C + C + C C Q C C
Sbjct: 348 PNDCFDRGRCIN----GTCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEEGQ----CVCD 396
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXX 599
G+ G +C++ K C RC +G C + G + G +
Sbjct: 397 EGFAGVDCSE------KRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 450
Query: 600 XDSXXXXXXXXXXXXXXQ--AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCR 657
+ Q C C C +G G C D+ + C
Sbjct: 451 VNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCH 507
Query: 658 NGGRCVGGSGWWMCECVAGWTGETCAVR 685
GRCV G MC C G+TGE C R
Sbjct: 508 QHGRCVNG----MCVCDDGYTGEDCRDR 531
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 134 bits (325), Expect = 1e-30
Identities = 154/561 (27%), Positives = 199/561 (35%), Gaps = 92/561 (16%)
Query: 194 GDKHCLPGWQGDNCEKPV--------CKEGCHPTH--GRCD-RPGDCDCRPGWRGELCSQ 242
G C PG G++CE C+E C RCD G C C PG+ G C
Sbjct: 668 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD 727
Query: 243 CQPY----PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC 291
P P C+ G+C+ ++ C+C W G C + + C H C
Sbjct: 728 VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC 787
Query: 292 E--NTAPDQY--FCRCAEGFSGVDCERV-----DNPCAPQPCAHGTCSLAGTTRGFTCTC 342
+ + D C C G+ G CE+ P Q C + G CTC
Sbjct: 788 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSG-ACTC 846
Query: 343 DRGWGGXXXXXXXXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDE 395
GW G G C GA+C D ++G +C C G GP CAE +
Sbjct: 847 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAE---K 901
Query: 396 CSGRSMTEGA--LGPCVNAAACNNTAGGYSCACLAGWTGRDCETN-VDDCTGQ-CLHGAT 451
C R + G G C+N C+ G C C AGWTG C++ + G+ C +
Sbjct: 902 CLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 959
Query: 452 CIDLVDDFH----CACAAGYAGRTCSLDVDDCAPRP-------CTNGGECVDLLNAYRCI 500
C H C C G+ G C P C NGG C A C
Sbjct: 960 CPPAAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGA--CR 1017
Query: 501 CPVGFSGTNCE---------DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
CP GF GT+C + H G CG GAAC C C PG G C +
Sbjct: 1018 CPTGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGT--CLCPPGRAGVRCERG 1073
Query: 552 AARDRKTCSVLVEESERCAE-GMC-ANGGTCVREEG-SWRXXXXXXXXXXXXDSXXXXXX 608
++R V E + C G+C A+ G+C G + R +
Sbjct: 1074 CPQNR--FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS 1131
Query: 609 XXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP-------CRNGGR 661
A GTC P + C R+GA C L P C G
Sbjct: 1132 CHNNSTCEPATGTC--RCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1189
Query: 662 CVGGSGWWMCECVAGWTGETC 682
C SG C CV G+ G TC
Sbjct: 1190 CDPVSG--QCHCVDGYMGPTC 1208
Score = 126 bits (305), Expect = 3e-28
Identities = 167/609 (27%), Positives = 200/609 (32%), Gaps = 93/609 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGC 216
C YY C C + H G C PG G C P C E C
Sbjct: 510 CPKGYYGKHCRKKCNCANRGRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 566
Query: 217 H---PTHGRCD-RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWD-CTCDTNWGGIL 271
P CD R G C C+ G+RGE C Q + C+ GY W CTC G+
Sbjct: 567 QCVQPHTQSCDKRDGSCSCKAGFRGERC-QAE----CELGYFGPGCWQACTCPV---GVA 618
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC--AHGTC 329
CD CG + C G E+ + C G GV+C C PC G C
Sbjct: 619 CDSVSGECG--KRCPAGFQGEDCGQE-----CPVGTFGVNCSS-SCSCGGAPCHGVTGQC 670
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
G C D G A C H A C D G C C G+ G C
Sbjct: 671 RCPPGRTGEDCEADCPEGRWGLGCQEICPA---CQHAARC-DPETG-ACLCLPGFVGSRC 725
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD------DCT 443
+DV + C N C+ G C+C GWTG C+ D DC+
Sbjct: 726 -QDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCS 782
Query: 444 G--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP-------CTNGGECVDLL 494
C G D + C C AGY G C P C +G C +
Sbjct: 783 HPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVS 841
Query: 495 NAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
A C CP G+ GT CE D + C GAAC C C G G
Sbjct: 842 GA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGRRGPR 897
Query: 548 CTQRA-ARD-RKTCSVLVEESERCAE-GMC-ANGGTCVREEGSWRXXXXXX--XXXXXXD 601
C ++ RD R C S C G+C + G C+ G W +
Sbjct: 898 CAEKCLPRDVRAGC----RHSGGCLNGGLCDPHTGRCLCPAG-WTGDKCQSPCLRGWFGE 952
Query: 602 SXXXXXXXXXXXXXXQAGGTCL--PSALPPGWACGCREGRTGALCELSLDLCGSSPCRNG 659
+ G C P G GC GR G CE LCG C NG
Sbjct: 953 ACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCE---QLCG---CLNG 1006
Query: 660 GRCVGGSGWWMCECVAGWTGETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPA 719
G C +G C C G+ G C + + T CLC
Sbjct: 1007 GSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT-CLC-- 1061
Query: 720 PPQRAARRC 728
PP RA RC
Sbjct: 1062 PPGRAGVRC 1070
Score = 121 bits (291), Expect = 1e-26
Identities = 132/462 (28%), Positives = 167/462 (36%), Gaps = 86/462 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--------PVCKE 214
+C +Y +C T C +D GH C P G C PGW G +C++ P C
Sbjct: 728 VCPAGWYGPSCQTRCSCAND--GH--CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSH 783
Query: 215 GCHPT--HGRCDR-PGDCDCRPGWRGELCSQCQPY----PGCK------HGY-CNGSSWD 260
C+ + HG CD G C C G+ G C Q P PGC+ HG C+ S
Sbjct: 784 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGA 843
Query: 261 CTCDTNWGGILCDQDLNY------CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
CTC W G C+ C + C G C+ C C G G C
Sbjct: 844 CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS---CLCPAGRRGPRCAE 900
Query: 315 VDNPCAPQP----CAH-GTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-CLHG 366
C P+ C H G C G T C C GW G G C
Sbjct: 901 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR 957
Query: 367 ASCRD-----HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
SC H+ G C C G+TG C + E G C+N +C+ G
Sbjct: 958 CSCPPAAACHHVTG-ACRCPPGFTGSGCEQGCPPGRYGPGCEQLCG-CLNGGSCDAATG- 1014
Query: 422 YSCACLAGWTGRDCETNVD------DCTGQCL--HGATCIDLVDDFHCACAAGYAGRTCS 473
+C C G+ G DC +CT C GA C + C C G AG C
Sbjct: 1015 -ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRCE 1071
Query: 474 LDVDD------CAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCE----DDRDHCA---G 519
C C NGG C N C C +G++G +CE R A
Sbjct: 1072 RGCPQNRFGVGCEHTCSCRNGGLC-HASNG-SCSCGLGWTGRHCELACPPGRYGAACHLE 1129
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
C N + C A C C PG+ G+ C R R TC++
Sbjct: 1130 CSCHNNSTCEPATGT--CRCGPGFYGQACEHR--RSGATCNL 1167
Score = 108 bits (260), Expect = 8e-23
Identities = 117/423 (27%), Positives = 149/423 (35%), Gaps = 65/423 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEGC 216
C ++ C C+ + G G C GW+G CE C+ C
Sbjct: 816 CPQGHFGPGCEQLCQCQH---GAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 872
Query: 217 HPTHGR-CDRP-GDCDCRPGWRGELCSQ-CQPYP---GCKH-------GYCNGSSWDCTC 263
+ T G CD G C C G RG C++ C P GC+H G C+ + C C
Sbjct: 873 NCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLC 932
Query: 264 DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF---CRCAEGFSGVDCERVDNPCA 320
W G C E C +C A + CRC GF+G CE+ P
Sbjct: 933 PAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPGR 992
Query: 321 PQPCAHGTCSL--AGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-CLH------GASC 369
P C G+ T C C G+ G GP C H GA+C
Sbjct: 993 YGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1052
Query: 370 RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
D + G TC C G G C + E C N C+ + G SC+C G
Sbjct: 1053 -DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNGGLCHASNG--SCSCGLG 1107
Query: 430 WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
WTGR CE G+ +GA C C+C + TC C P G
Sbjct: 1108 WTGRHCELACP--PGR--YGAAC-----HLECSC---HNNSTCEPATGTCRCGPGFYGQA 1155
Query: 490 CVDLLNAYRC--ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
C + C C G G +C HC CG GA C CHC G+ G
Sbjct: 1156 CEHRRSGATCNLDCRRGQFGPSC---TLHC---DCGGGADCDPVSGQ--CHCVDGYMGPT 1207
Query: 548 CTQ 550
C +
Sbjct: 1208 CRE 1210
Score = 101 bits (241), Expect = 2e-20
Identities = 107/325 (32%), Positives = 125/325 (38%), Gaps = 64/325 (19%)
Query: 275 DLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCA--PQPCAHG 327
D++ C TH CQH C NT P Y C C GF C + N CA C H
Sbjct: 73 DVDECRTHNGGCQH--RCVNT-PGSYLCECKPGFRLHTDSRTCLAI-NSCALGNGGCQHH 128
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
L T C C G+ G +G C+H C+ CEC
Sbjct: 129 CVQLTITRH--RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHV 184
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRD 434
G+ G AC EDVDEC+ L C A C NT G + C C AG+ GR
Sbjct: 185 GYQLAADGKAC-EDVDECAA------GLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQ 235
Query: 435 C---ETN-VDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRP 483
C E V+ C G C HG C C C GY RTC +DVDDCA P
Sbjct: 236 CYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTC-IDVDDCADSP 292
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C C + Y C C G+ G CED D CA S G C + C C
Sbjct: 293 CCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDV-DECASSRGGCEHHCTNLAGSFQCSC 350
Query: 540 APGWTGKNCTQRAARDRKTCSVLVE 564
G+ R DR+ CS L E
Sbjct: 351 EAGY-------RLHEDRRGCSPLEE 368
Score = 96.7 bits (230), Expect = 4e-19
Identities = 97/335 (28%), Positives = 124/335 (37%), Gaps = 58/335 (17%)
Query: 261 CTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCER 314
C C W G++C++ C CQ+GGTC++ CRC G SG +CE
Sbjct: 452 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA---CRCPPGVSGTNCED 508
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGP-------C 363
C+ A R C CD G G A GP C
Sbjct: 509 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 568
Query: 364 L--HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVN--AAACNNTA 419
+ H SC D DG +C C G+ G C EC G C AC++ +
Sbjct: 569 VQPHTQSC-DKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVS 623
Query: 420 GGYSCACLAGWTGRDC--ETNVD----DCTGQC-LHGATCIDLVDDFHCACAAGYAGRTC 472
G C AG+ G DC E V +C+ C GA C + C C G G C
Sbjct: 624 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ--CRCPPGRTGEDC 681
Query: 473 SLDVDD------CAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--- 521
D + C C + C A C+C GF G+ C+D P
Sbjct: 682 EADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQ 739
Query: 522 ----CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
C N C+ A +C CAPGWTG +C QRA
Sbjct: 740 TRCSCANDGHCHPATG--HCSCAPGWTGFSC-QRA 771
Score = 81.0 bits (191), Expect = 2e-14
Identities = 126/445 (28%), Positives = 156/445 (35%), Gaps = 102/445 (22%)
Query: 215 GCHPTHGRCDRPGD--CDCRPGWRGELCSQ-CQPYPGCK--HGYCNGSSWDCTCDTN--- 266
GC H + PG C+C+PG+R S+ C C +G C T +
Sbjct: 83 GCQ--HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 140
Query: 267 -WGGILCDQDLNYCGTHEPC-QHGGTCEN---TAPDQYFCRCAEGF----SGVDCERVDN 317
G +D +C PC G+C + C C G+ G CE VD
Sbjct: 141 CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE 200
Query: 318 PCAP--QPCAHGTCSLAGTTRGFTCTCDRGW--GG--------XXXXXXXXXXASGPCLH 365
CA CAHG + G+ F C C G+ G +G C H
Sbjct: 201 -CAAGLAQCAHGCLNTQGS---FKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 256
Query: 366 GASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
G C G C C G+ T DVD+C A PC C N GGY
Sbjct: 257 G--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--------ADSPCCQ-QVCTNNPGGY 305
Query: 423 SCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRT 471
C C AG+ G CE +VD+C G C H C +L F C+C AGY R
Sbjct: 306 ECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRG 362
Query: 472 CS------LDVDDCAP--RPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDH------- 516
CS +D+D P RP + D L VG E +H
Sbjct: 363 CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFV 422
Query: 517 CA----GSPCG-------NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR--KTCSVLV 563
C G C NG C C C GWTG C + D K CS
Sbjct: 423 CLDDSFGHDCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSF-- 478
Query: 564 EESERCAEGMCANGGTCVREEGSWR 588
C+ C NGGTC G+ R
Sbjct: 479 ----SCS---CQNGGTCDSVTGACR 496
Score = 64.9 bits (151), Expect = 1e-09
Identities = 79/282 (28%), Positives = 99/282 (35%), Gaps = 48/282 (17%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDV--DDC 479
CL G DC DDC +G TC+ +D C C G+ G TC D +C
Sbjct: 423 CLDDSFGHDCSLTCDDCR----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNC 476
Query: 480 A-PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD------RDHCAGS-PCGNGAACYTA 531
+ C NGG C + A C CP G SGTNCED HC C N C+
Sbjct: 477 SFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 534
Query: 532 QSDYYCHCAPGWTGKNCTQR------AARDRKTCSVLVEESERC--AEGMCA-NGGTCVR 582
C C PG G+ C + C + ++ C +G C+ G R
Sbjct: 535 YG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG--FR 590
Query: 583 EEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG--CREGRT 640
E + + G C P+ G CG C G
Sbjct: 591 GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRC-PAGF-QGEDCGQECPVGTF 648
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
G C S CG +PC G +G C C G TGE C
Sbjct: 649 GVNCSSSCS-CGGAPCH------GVTG--QCRCPPGRTGEDC 681
Score = 61.7 bits (143), Expect = 1e-08
Identities = 73/268 (27%), Positives = 101/268 (37%), Gaps = 47/268 (17%)
Query: 434 DCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN 486
D +VD+C G C H C++ + C C G+ RTC L ++ CA N
Sbjct: 69 DQRPDVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCA---LGN 122
Query: 487 GG---ECVDL-LNAYRCICPVGFSGTNCEDDRDHCAG-SPCGN--GAA---CYTAQSDYY 536
GG CV L + +RC C GF ++D HC SPC N G+ C +
Sbjct: 123 GGCQHHCVQLTITRHRCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 179
Query: 537 CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGTCVREEGSWRXXXXXX 594
C C G+ + A D K C E+ + CA G+ CA+G C+ +GS++
Sbjct: 180 CECHVGY-------QLAADGKAC----EDVDECAAGLAQCAHG--CLNTQGSFKCVCHAG 226
Query: 595 XXXXXXDSXXXXXXXXXXXXXXQAGGTCLP--SALPPGWACGCREG---RTGALCELSLD 649
G C S G C C G T + +D
Sbjct: 227 YELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 286
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGW 677
C SPC C G + C C AG+
Sbjct: 287 DCADSPCCQ-QVCTNNPGGYECGCYAGY 313
Score = 56.8 bits (131), Expect = 4e-07
Identities = 81/309 (26%), Positives = 106/309 (34%), Gaps = 50/309 (16%)
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT---G 444
DVDEC + G C + C NT G Y C C G+ R C ++ C G
Sbjct: 73 DVDECRTHN------GGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLA-INSCALGNG 123
Query: 445 QCLHGATCIDLVDDFH-CACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C H C+ L H C C G+ GR C + CA R + C + RC
Sbjct: 124 GCQHH--CVQLTITRHRCQCRPGFQLQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARC 180
Query: 500 ICPVGFS----GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
C VG+ G CED + AG + C +G C Q + C C G+ + A
Sbjct: 181 ECHVGYQLAADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGY------ELGAD 232
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
R+ + +E C AN G C G
Sbjct: 233 GRQCYRIEMEIVNSCE----ANNGGC--SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 286
Query: 615 XXQAGGTCLPSAL--PPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGW 668
C P G+ CGC G G CE +D C SS C +G
Sbjct: 287 DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGS 345
Query: 669 WMCECVAGW 677
+ C C AG+
Sbjct: 346 FQCSCEAGY 354
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
+G C H C + + CEC G+ D C + G C + T
Sbjct: 81 NGGCQH--RCVNTPGSYLCECKPGFR---LHTDSRTCLAINSCALGNGGCQHHCV-QLTI 134
Query: 420 GGYSCACLAGWT----GRDC--ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA----G 469
+ C C G+ GR C + + G C+H C + C C GY G
Sbjct: 135 TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADG 192
Query: 470 RTCSLDVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNC----EDDRDHCAG 519
+ C DVD+CA C +G C++ +++C+C G+ G C + + C
Sbjct: 193 KACE-DVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 249
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ G C + C C G+ + QR D C+ C + +C N
Sbjct: 250 NNGGCSHGCSHTSAGPLCTCPRGYE-LDTDQRTCIDVDDCA-----DSPCCQQVCTN 300
>AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 288
Score = 133 bits (321), Expect = 3e-30
Identities = 61/156 (39%), Positives = 86/156 (55%), Gaps = 11/156 (7%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVD--ECSGRS-MTEGALGPCVNAAACNNTA 419
C HG +C + C C GW G C + +C ++ E A PC N C +
Sbjct: 2 CQHG-TCHQP---WQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQ 57
Query: 420 G---GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
G ++C CL G+ G CE NVDDC + C +GATC+D ++ F C C G+AGR C+++
Sbjct: 58 GFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTIN 117
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+DDCA RPC G C D ++ + C+CP G+ G CE
Sbjct: 118 LDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCE 153
Score = 121 bits (291), Expect = 1e-26
Identities = 56/148 (37%), Positives = 71/148 (47%), Gaps = 6/148 (4%)
Query: 407 GPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCID---LVDDFH 460
G C C +G C G+ GRDCE C C +G C D +F
Sbjct: 5 GTCHQPWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFT 64
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C G+ G C ++VDDC RPC NG C+D +N + C+CP GF+G C + D CA
Sbjct: 65 CRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR 124
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
PC GA C D+ C C G+ GK C
Sbjct: 125 PCQRGARCRDRVHDFDCLCPSGYGGKTC 152
Score = 107 bits (256), Expect = 3e-22
Identities = 59/166 (35%), Positives = 73/166 (43%), Gaps = 28/166 (16%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX-----------ASGPCLHGASCRDH 372
C HGTC + + C C GW G A PC +G C+D
Sbjct: 2 CQHGTCH-----QPWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDD 56
Query: 373 LD---GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
FTC C G+ G C +VD+C R PC N A C + +SC C G
Sbjct: 57 QGFALNFTCRCLVGFVGARCEVNVDDCLMR--------PCANGATCLDGINRFSCLCPEG 108
Query: 430 WTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ GR C N+DDC + C GA C D V DF C C +GY G+TC L
Sbjct: 109 FAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 154
Score = 94.3 bits (224), Expect = 2e-18
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 22/163 (13%)
Query: 285 CQHGGTCENTAPDQYFCR-------CAEGFSGVDCERVDNPC--APQPCAHG-TCSL-AG 333
CQHG TC P Q C C +GF G DCER PC A PC +G C G
Sbjct: 2 CQHG-TCHQ--PWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQG 58
Query: 334 TTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
FTC C G+ G PC +GA+C D ++ F+C C +G+ G C ++
Sbjct: 59 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINL 118
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
D+C+ R PC A C + + C C +G+ G+ CE
Sbjct: 119 DDCASR--------PCQRGARCRDRVHDFDCLCPSGYGGKTCE 153
Score = 76.6 bits (180), Expect = 4e-13
Identities = 38/93 (40%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 463 CAAGYAGRTCSLDVDDC--APRPCTNGGECVD----LLNAYRCICPVGFSGTNCEDDRDH 516
C G+ GR C C A PC NGG+C D LN + C C VGF G CE + D
Sbjct: 24 CDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN-FTCRCLVGFVGARCEVNVDD 82
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
C PC NGA C + + C C G+ G+ CT
Sbjct: 83 CLMRPCANGATCLDGINRFSCLCPEGFAGRFCT 115
Score = 71.7 bits (168), Expect = 1e-11
Identities = 47/162 (29%), Positives = 67/162 (41%), Gaps = 16/162 (9%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPY 246
H +C C GW G C+K C G C++ G CR G QCQ
Sbjct: 4 HGTCHQPWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGS-PCRNG------GQCQDD 56
Query: 247 PGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG 306
G ++ C C + G C+ +++ C PC +G TC + +++ C C EG
Sbjct: 57 QGF------ALNFTCRCLVGFVGARCEVNVDDC-LMRPCANGATCLD-GINRFSCLCPEG 108
Query: 307 FSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
F+G C + CA +PC G F C C G+GG
Sbjct: 109 FAGRFCTINLDDCASRPCQRG-ARCRDRVHDFDCLCPSGYGG 149
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/153 (27%), Positives = 59/153 (38%), Gaps = 6/153 (3%)
Query: 530 TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRX 589
T + C C GW GK C + + C E+ A C NGG C ++G +
Sbjct: 6 TCHQPWQCICHSGWAGKFCDK--GFHGRDCERKAGPCEQ-AGSPCRNGGQCQDDQG-FAL 61
Query: 590 XXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD 649
+ G TCL ++C C EG G C ++LD
Sbjct: 62 NFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI--NRFSCLCPEGFAGRFCTINLD 119
Query: 650 LCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S PC+ G RC + C C +G+ G+TC
Sbjct: 120 DCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 152
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/136 (29%), Positives = 57/136 (41%), Gaps = 18/136 (13%)
Query: 196 KHCLPGWQGDNCEKPV--CKEGCHPTH--GRC-DRPG-----DCDCRPGWRGELCS---- 241
K C G+ G +CE+ C++ P G+C D G C C G+ G C
Sbjct: 22 KFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 81
Query: 242 QCQPYPGCKHGYC-NG-SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQY 299
C P C +G + + C C + G C +L+ C + PCQ G C + D +
Sbjct: 82 DCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASR-PCQRGARCRDRVHD-F 139
Query: 300 FCRCAEGFSGVDCERV 315
C C G+ G CE V
Sbjct: 140 DCLCPSGYGGKTCELV 155
Score = 52.4 bits (120), Expect = 8e-06
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 619 GGTCLPS-ALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
GG C + C C G GA CE+++D C PC NG C+ G + C C G+
Sbjct: 50 GGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGF 109
Query: 678 TGETCAVRV 686
G C + +
Sbjct: 110 AGRFCTINL 118
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 19/108 (17%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC--AGSPCGNGAACYTAQS--- 533
C C +C+ C GF G +CE C AGSPC NG C Q
Sbjct: 2 CQHGTCHQPWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL 61
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
++ C C G+ G AR C V V++ C CANG TC+
Sbjct: 62 NFTCRCLVGFVG-------AR----CEVNVDD---CLMRPCANGATCL 95
Score = 46.4 bits (105), Expect = 5e-04
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
Query: 630 GWACG-CREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGW---WMCECVAGWTGETCA 683
GWA C +G G CE C SPCRNGG+C G+ + C C+ G+ G C
Sbjct: 18 GWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE 77
Query: 684 VRV 686
V V
Sbjct: 78 VNV 80
>BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein.
Length = 249
Score = 132 bits (320), Expect = 5e-30
Identities = 78/243 (32%), Positives = 114/243 (46%), Gaps = 17/243 (6%)
Query: 322 QPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC--RDHLDGFTC 378
+PC + G C G+ C C G+ G + C +G +C + L TC
Sbjct: 7 EPCVNEGMCVTYHNGTGY-CKCPEGFLGEYCQHRDPCEKNR-CQNGGTCVAQAMLGKATC 64
Query: 379 ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTGRDCET 437
CA G+TG C S PC+N C+ + Y C C G+TG++C+
Sbjct: 65 RCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSRDTYECTCQVGFTGKECQW 118
Query: 438 NVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC-APRPCTNGGECVDLLN 495
D C C +G+TC + + F C C G+ G+ C DV++C P C +GG C++L
Sbjct: 119 -TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPG 177
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYYCHCAPGWTGKNCTQRAAR 554
+Y+C C GF+G C+ CA SPC NG C T + C+C P T + T+ R
Sbjct: 178 SYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPE-TVRRGTELWER 236
Query: 555 DRK 557
DR+
Sbjct: 237 DRE 239
Score = 126 bits (303), Expect = 5e-28
Identities = 76/232 (32%), Positives = 104/232 (44%), Gaps = 29/232 (12%)
Query: 362 PCLHGASCRDHLDGFT-CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
PC++ C + +G C+C +G+ G C + D C G G CV A G
Sbjct: 8 PCVNEGMCVTYHNGTGYCKCPEGFLGEYC-QHRDPCEKNRCQNG--GTCVAQAML----G 60
Query: 421 GYSCACLAGWTGRDCETNVDD-C--TGQCLHGATCIDLV-DDFHCACAAGYAGRTCSLDV 476
+C C +G+TG DC+ + C + CL+G TC L D + C C G+ G+ C
Sbjct: 61 KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-T 119
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC-AGSPCGNGAACYTAQSDY 535
D C PC NG C + N + C C GF+G CE D + C C +G C Y
Sbjct: 120 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSY 179
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C C G+TG+ C S+ V CA C NGGTC R+ G +
Sbjct: 180 QCQCLQGFTGQYCD----------SLYVP----CAPSPCVNGGTC-RQTGDF 216
Score = 109 bits (262), Expect = 5e-23
Identities = 63/188 (33%), Positives = 85/188 (45%), Gaps = 22/188 (11%)
Query: 408 PCVNAAACNNTAGGYS-CACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCAC 463
PCVN C G C C G+ G C+ D C +C +G TC+ ++ C C
Sbjct: 8 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRC 66
Query: 464 AAGYAGRTCSLDVDD-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGS 520
A+G+ G C C RPC NGG C L + Y C C VGF+G C+ D C
Sbjct: 67 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSH 125
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC NG+ C T + + C C G+TG+ C D C + G C +GG C
Sbjct: 126 PCANGSTCTTVANQFSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGIC 172
Query: 581 VREEGSWR 588
+ GS++
Sbjct: 173 LNLPGSYQ 180
Score = 103 bits (248), Expect = 2e-21
Identities = 72/243 (29%), Positives = 98/243 (40%), Gaps = 28/243 (11%)
Query: 211 VCKEGCHP--THGRC----DRPGDCDCRPGWRGELCSQCQPYPG--CKHG-YCNGSSW-- 259
+C++G P G C + G C C G+ GE C P C++G C +
Sbjct: 1 MCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLG 60
Query: 260 --DCTCDTNWGGILCDQDLNY-CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C C + + G C ++ C PC +GGTC + D Y C C GF+G +C+ D
Sbjct: 61 KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD 120
Query: 317 NPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLD 374
C PCA+G TC+ F+C C G+ G G C HG C +
Sbjct: 121 -ACLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPG 177
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGR 433
+ C+C G+TG C C A PCVN C T + C CL R
Sbjct: 178 SYQCQCLQGFTGQYCDSLYVPC--------APSPCVNGGTCRQTGDFTFECNCLPETVRR 229
Query: 434 DCE 436
E
Sbjct: 230 GTE 232
Score = 99.1 bits (236), Expect = 7e-20
Identities = 70/236 (29%), Positives = 93/236 (39%), Gaps = 28/236 (11%)
Query: 446 CLHGATCIDLVDDF-HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICP 502
C++ C+ + +C C G+ G C D C C NGG CV +L C C
Sbjct: 9 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCA 67
Query: 503 VGFSGTNCEDDRDH-CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTC 559
GF+G +C+ H C S PC NG C+ D Y C C G+TGK C
Sbjct: 68 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC----------- 116
Query: 560 SVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAG 619
+ ++ C CANG TC + ++ Q G
Sbjct: 117 ----QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHG 169
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
G CL LP + C C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 GICLN--LPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 223
Score = 79.0 bits (186), Expect = 8e-14
Identities = 59/204 (28%), Positives = 79/204 (38%), Gaps = 23/204 (11%)
Query: 483 PCTNGGECVDLLNAYR-CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHC 539
PC N G CV N C CP GF G C+ RD C + C NG C C C
Sbjct: 8 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRC 66
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXX 599
A G+TG++C + C V C NGGTC R
Sbjct: 67 ASGFTGEDCQYSTSHP---CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGF 111
Query: 600 XDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRN 658
G TC + + ++C C G TG CE ++ C C++
Sbjct: 112 TGKECQWTDACLSHPCAN-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQH 168
Query: 659 GGRCVGGSGWWMCECVAGWTGETC 682
GG C+ G + C+C+ G+TG+ C
Sbjct: 169 GGICLNLPGSYQCQCLQGFTGQYC 192
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 18/168 (10%)
Query: 521 PCGNGAACYTAQSDY-YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
PC N C T + YC C G+ G+ C R + C + C NGGT
Sbjct: 8 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGT 52
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV + + D GGTC + + C C+ G
Sbjct: 53 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGF 111
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
TG C+ + D C S PC NG C + + C+C+ G+TG+ C V+
Sbjct: 112 TGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 158
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 132 bits (319), Expect = 6e-30
Identities = 128/451 (28%), Positives = 173/451 (38%), Gaps = 83/451 (18%)
Query: 198 CLPGW--QGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS----------QCQP 245
C PG+ G+ C P C + C HGRC P C C PGW G CS C
Sbjct: 94 CCPGFYESGEMCV-PHCADKC--VHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS 150
Query: 246 YPGCKHG-YCNGSSWDCTCDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQ 298
CK+G CN + C C + G C+ N C CQ+G TC++ +
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE- 209
Query: 299 YFCRCAEGFSGVDCERVDNP--CAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXX 354
CRC G++G CE + P PQ C G T C+C GW G
Sbjct: 210 --CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP 267
Query: 355 XXXXASG-------PCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC--SGRSMTEGA 405
G C +G +C D G C C+ G+TG C DEC +
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTC-DAATG-QCHCSPGYTGERCQ---DECPVGTYGVLCAE 322
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNV--DDCTG-QCLHGATC-IDLVDDFH- 460
CVN C + +G +C C AG+ G CE + + G +C C ++ H
Sbjct: 323 TCQCVNGGKCYHVSG--ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHP 380
Query: 461 ----CACAAGYAGRTCSLDVDDCAPR----------PCTNGGECVDLLNAYRCICPVGFS 506
CAC G++G C+ + C+P C NG +C + +C C GF
Sbjct: 381 MSGECACKPGWSGLYCN---ETCSPGFYGEACQQICSCQNGADCDSVTG--KCTCAPGFK 435
Query: 507 GTNCEDDRD------HCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
G +C +C+ C N A C + D C C GW G +C+ R T
Sbjct: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAVC--SPVDGSCTCKAGWHGVDCSIRCPSG--TW 491
Query: 560 SVLVEESERCAEGMCAN--GGTCVREEGSWR 588
+ +C G N GTC G WR
Sbjct: 492 GFGCNLTCQCLNGGACNTLDGTCTCAPG-WR 521
Score = 126 bits (304), Expect = 4e-28
Identities = 120/445 (26%), Positives = 172/445 (38%), Gaps = 82/445 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQG----DNCEKPV----CKEG 215
C +++ CT+ C+ ++ C P G HC G++G D CE+ C +
Sbjct: 139 CDGDHWGPHCTSRCQCKNGAL----CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQR 194
Query: 216 CHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
C +G CD G+C C PG+ G C QC+ C++G C+ + +C+
Sbjct: 195 CQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECS 254
Query: 263 CDTNWGGILCDQDL------NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD 316
C + W G +C Q C C +GGTC+ A Q C C+ G++G C+ +
Sbjct: 255 CPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCD-AATGQ--CHCSPGYTGERCQD-E 310
Query: 317 NPCAPQP--CAHGTCSLAGTTRGF----TCTCDRGWGGXXXXXXXXXXASGPCLHGASCR 370
P CA TC + + C C+ G+ G C
Sbjct: 311 CPVGTYGVLCAE-TCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP 369
Query: 371 DHLDGF--------TCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAG 420
HL+ C C GW+G C E CS E + C N A C++ G
Sbjct: 370 CHLENTHSCHPMSGECACKPGWSGLYCNET---CSPGFYGEACQQICSCQNGADCDSVTG 426
Query: 421 GYSCACLAGWTGRDCETNVD------DCTGQC--LHGATCIDLVDDFHCACAAGYAGRTC 472
C C G+ G DC T +C+ +C + A C + D C C AG+ G C
Sbjct: 427 --KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPV--DGSCTCKAGWHGVDC 482
Query: 473 SLDVDD------C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHCAGSPCGN 524
S+ C C NGG C L C C G+ G CE +D G C
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAE 540
Query: 525 GAACYTAQSDY----YCHCAPGWTG 545
C A + +C C PGW+G
Sbjct: 541 RCDCSHADGCHPTTGHCRCLPGWSG 565
Score = 119 bits (287), Expect = 4e-26
Identities = 130/460 (28%), Positives = 170/460 (36%), Gaps = 104/460 (22%)
Query: 165 CQPNYYNT--TCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--------PVCKE 214
C P +Y + C C DK H C C PGW G NC P C
Sbjct: 94 CCPGFYESGEMCVPHCA---DKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS 150
Query: 215 GCHPTHGRCDRP--GDCDCRPGWRGELC----------SQCQPYPGCKHG-YCNGSSWDC 261
C +G P G C C G+RG C + C C++G C+ + +C
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC 210
Query: 262 TCDTNWGGILCDQDLNYCGTHE-------PCQHGGTCENTAPDQYFCRCAEGFSGVDC-- 312
C + G C +DL G H PCQ+GG C + + C C G+ G C
Sbjct: 211 RCPPGYTGAFC-EDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE---CSCPSGWMGTVCGQ 266
Query: 313 ----ERVDNPCAPQPCAH--GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG----- 361
R C+ + H GTC A T + C C G+ G G
Sbjct: 267 PCPEGRFGKNCSQECQCHNGGTCD-AATGQ---CHCSPGYTGERCQDECPVGTYGVLCAE 322
Query: 362 --PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG-------PC--V 410
C++G C H+ G C C G+ G + C R EG G PC
Sbjct: 323 TCQCVNGGKCY-HVSG-ACLCEAGFAG-------ERCEARLCPEGLYGIKCDKRCPCHLE 373
Query: 411 NAAACNNTAGGYSCACLAGWTGRDC-ETNVDDCTGQ-------CLHGATCIDLVDDFHCA 462
N +C+ +G CAC GW+G C ET G+ C +GA C + C
Sbjct: 374 NTHSCHPMSG--ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG--KCT 429
Query: 463 CAAGYAGRTCSLDVD------DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
CA G+ G CS +C+ R C N C + + C C G+ G +C
Sbjct: 430 CAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCP 487
Query: 516 H------C-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
C C NG AC T D C CAPGW G+ C
Sbjct: 488 SGTWGFGCNLTCQCLNGGACNTL--DGTCTCAPGWRGEKC 525
Score = 110 bits (265), Expect = 2e-23
Identities = 132/489 (26%), Positives = 174/489 (35%), Gaps = 94/489 (19%)
Query: 231 CRPGW--RGELC-SQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
C PG+ GE+C C C HG C + C C+ WGG C + G H
Sbjct: 94 CCPGFYESGEMCVPHCADK--CVHGRCIAPN-TCQCEPGWGGTNCSSACD--GDH----W 144
Query: 288 GGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT--CDRG 345
G C + C+C G + NP G C A RG+ C C++G
Sbjct: 145 GPHCTSR------CQCKNG-------ALCNPIT------GACHCAAGFRGWRCEDRCEQG 185
Query: 346 WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G C +GA+C DH+ G C C G+TG C ED+
Sbjct: 186 TYGNDCHQRCQ------CQNGATC-DHVTG-ECRCPPGYTGAFC-EDLCPPGKHGPQCEQ 236
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDD------CTG--QCLHGATCIDLVD 457
PC N C++ G C+C +GW G C + C+ QC +G TC D
Sbjct: 237 RCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC-DAAT 293
Query: 458 DFHCACAAGYAGRTCSLDVDD------CAPR-PCTNGGECVDLLNAYRCICPVGFSGTNC 510
C C+ GY G C + CA C NGG+C + A C+C GF+G C
Sbjct: 294 G-QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERC 350
Query: 511 EDDR--DHCAGSPCGNGAACYTAQSDYYCH-------CAPGWTGKNCTQRAARDRKTCSV 561
E + G C C+ ++ + CH C PGW+G C + TCS
Sbjct: 351 EARLCPEGLYGIKCDKRCPCHL-ENTHSCHPMSGECACKPGWSGLYCNE-------TCSP 402
Query: 562 LVEESERCAE-GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
E C + C NG C G S + G
Sbjct: 403 GFY-GEACQQICSCQNGADCDSVTGKCTCAPGFKGIDC---STPCPLGTYGINCSSRCGC 458
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDL------CG-SSPCRNGGRCVGGSGWWMCEC 673
P +C C+ G G C + C + C NGG C G C C
Sbjct: 459 KNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDG--TCTC 516
Query: 674 VAGWTGETC 682
GW GE C
Sbjct: 517 APGWRGEKC 525
Score = 89.8 bits (213), Expect = 4e-17
Identities = 97/356 (27%), Positives = 126/356 (35%), Gaps = 64/356 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG-------- 215
LC P + C C ++ H+ G+ C GW G C +P C EG
Sbjct: 224 LCPPGKHGPQCEQRCPCQNGGVCHHVT---GECSCPSGWMGTVCGQP-CPEGRFGKNCSQ 279
Query: 216 ---CHPTHGRCDRP-GDCDCRPGWRGELCSQ----------CQPYPGCKHG-YCNGSSWD 260
CH G CD G C C PG+ GE C C C +G C S
Sbjct: 280 ECQCH-NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA 338
Query: 261 CTCDTNWGGILCDQDLNYCGTHE-PCQHGGTC--ENTA---PDQYFCRCAEGFSGVDCER 314
C C+ + G C+ L G + C C ENT P C C G+SG+ C
Sbjct: 339 CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE 398
Query: 315 VDNP-----CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG-PCLHGAS 368
+P Q C+ + + G CTC G+ G G C
Sbjct: 399 TCSPGFYGEACQQICSCQNGADCDSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCG 457
Query: 369 CRDH-----LDGFTCECADGWTGPACAEDVDECSGRSMTEGA--LGPCVNAAACNNTAGG 421
C++ +DG +C C GW G C+ C + G C+N ACN G
Sbjct: 458 CKNDAVCSPVDG-SCTCKAGWHGVDCSI---RCPSGTWGFGCNLTCQCLNGGACNTLDG- 512
Query: 422 YSCACLAGWTGRDCETNVDDCT--------GQCLHGATCIDLVDDFHCACAAGYAG 469
+C C GW G CE D T C H C HC C G++G
Sbjct: 513 -TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSG 565
Score = 75.4 bits (177), Expect = 1e-12
Identities = 78/273 (28%), Positives = 92/273 (33%), Gaps = 43/273 (15%)
Query: 436 ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD------CAPR-PCTNGG 488
E V C +C+HG CI C C G+ G CS D C R C NG
Sbjct: 103 EMCVPHCADKCVHGR-CIA---PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGA 158
Query: 489 ECVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
C + A C C GF G CED D C NGA C + C C P
Sbjct: 159 LCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPP 214
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+TG C + +RC C NGG C G
Sbjct: 215 GYTGAFCEDLCPPGKHGPQC----EQRCP---CQNGGVCHHVTGECSCPSGWMGTVCGQP 267
Query: 602 SXXXXXXXXXXXXXX-QAGGTCLPSALPPGWACGCREGRTGALCELSLD------LCGSS 654
GGTC + C C G TG C+ LC +
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTCDAAT----GQCHCSPGYTGERCQDECPVGTYGVLCAET 323
Query: 655 -PCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C NGG+C SG C C AG+ GE C R+
Sbjct: 324 CQCVNGGKCYHVSG--ACLCEAGFAGERCEARL 354
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 26/128 (20%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCE----KPVCKEGCHPT 219
C Y C++ C ++D C+P DG C GW G +C GC+ T
Sbjct: 443 CPLGTYGINCSSRCGCKNDAV----CSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLT 498
Query: 220 -----HGRCDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDCT 262
G C+ G C C PGWRGE C C C H C+ ++ C
Sbjct: 499 CQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCR 558
Query: 263 CDTNWGGI 270
C W G+
Sbjct: 559 CLPGWSGL 566
>AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein
protein.
Length = 626
Score = 131 bits (317), Expect = 1e-29
Identities = 130/484 (26%), Positives = 179/484 (36%), Gaps = 83/484 (17%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPV--------CKEGC 216
C P + C+ C G G HC G+ GD C++ C + C
Sbjct: 13 CPPGTFGQNCSQDCPCHH---GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRC 69
Query: 217 H-PTHGRCD-RPGDCDCRPGWRG-----ELCSQCQPYPGC---------KHGYCNGSSWD 260
G+C G C+C PG++G LC + PGC C+ +
Sbjct: 70 DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 129
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF---CRCAEGFSGVDC--ERV 315
CTC W G C++ + CQ TC+N A C CA GF G C
Sbjct: 130 CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 189
Query: 316 DNPCAPQPCAHGTCSLAGTTRGF--TCTCDRGWGGXXXXXXXXXXASG-------PCLHG 366
P + +C+ GT +CTC GW G G C +G
Sbjct: 190 AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 249
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV-DECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
A+C +DG +C C GW G C D G + +E C +A C+ G C
Sbjct: 250 AAC-SPIDG-SCSCTPGWLGDTCELPCPDGTFGLNCSEHC--DCSHADGCDPVTG--HCC 303
Query: 426 CLAGWTGRDCETNV------DDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC----- 472
CLAGWTG C++ +C+ C +G +C +D C CA G+ G C
Sbjct: 304 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSP--EDGSCECAPGFRGPLCQRICP 361
Query: 473 -SLDVDDCA-PRP-CTNGGECVDLLNAYRCICPVGFSGTNCED-------DRDHCAGSPC 522
CA P P C + ++ C C GFSG C +D C
Sbjct: 362 PGFYGHGCAQPCPLCVHSSRPCHHISGI-CECLPGFSGALCNQVCAGGYFGQDCAQLCSC 420
Query: 523 GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVR 582
N C + D C C PGW GK+C+Q + C+ C NG +C
Sbjct: 421 ANNGTC--SPIDGSCQCFPGWIGKDCSQACPPGFWGPACF----HACS---CHNGASCSA 471
Query: 583 EEGS 586
E+G+
Sbjct: 472 EDGA 475
Score = 128 bits (308), Expect = 1e-28
Identities = 132/428 (30%), Positives = 158/428 (36%), Gaps = 76/428 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--PV------CKE 214
LC + CT C P D SC P G C PGW G +C + PV C+
Sbjct: 99 LCPEGLHGPGCTLPC-PCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL 156
Query: 215 GCHPTHGR-CDR-PGDCDCRPGWRGELCS----------QCQPYPGCKHG-YCNGSSWDC 261
C +G C G C C PG+ GE+C+ C C +G C+ C
Sbjct: 157 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 216
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDCERV--D 316
TC W G+ C C TC N A P C C G+ G CE D
Sbjct: 217 TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPD 276
Query: 317 NPCAPQPCAHGTCSLAGTTRGFT--CTCDRGWGGXXXXXXXXXXASGP-------CLHGA 367
H CS A T C C GW G GP C +G
Sbjct: 277 GTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 336
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYS 423
SC DG +CECA G+ GP C C G PC ++ C++ +G
Sbjct: 337 SCSPE-DG-SCECAPGFRGPLCQRI---CPPGFYGHGCAQPCPLCVHSSRPCHHISG--I 389
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C CL G++G C C G G C L C+CA TCS C P
Sbjct: 390 CECLPGFSGALCN---QVCAGGYF-GQDCAQL-----CSCANN---GTCSPIDGSCQCFP 437
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
G +C CP GF G C H C NGA+C + D CHC PGW
Sbjct: 438 GWIGKDCSQA-------CPPGFWGPACF----HACS--CHNGASC--SAEDGACHCTPGW 482
Query: 544 TGKNCTQR 551
TG CTQR
Sbjct: 483 TGLFCTQR 490
Score = 123 bits (297), Expect = 3e-27
Identities = 141/518 (27%), Positives = 181/518 (34%), Gaps = 103/518 (19%)
Query: 231 CRPGWRGELCSQCQPYPGCKHG-YCNGSSWDCTCDTNWGGILCDQDLNY------CGTHE 283
C PG G+ CSQ P C HG C+ + C C + G C ++ + C
Sbjct: 13 CPPGTFGQNCSQDCP---CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRC 69
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNP-CA-PQPC-AHGTCSLAGT 334
C +GG C +P C C G+ G C E + P C P PC A T S
Sbjct: 70 DCHNGGQC---SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPV 126
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLHGASCRDHLDGFTCECADGWTGP 387
T CTC GW G G C +GA C G C CA G+ G
Sbjct: 127 TGA--CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGE 182
Query: 388 ACAEDVDECSGRSMTEGALGP-CVNAAACNNTAGGY------SCACLAGWTGRDCETNV- 439
CA S G GP C + +CNN GG SC C GW G DC
Sbjct: 183 VCAV--------SCAAGTYGPNCSSICSCNN--GGTCSPVDGSCTCKEGWQGLDCTLPCP 232
Query: 440 ---------DDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD------CAPR-P 483
+ CT C +GA C + D C+C G+ G TC L D C+
Sbjct: 233 SGTWGLNCNESCT--CANGAACSPI--DGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCD 288
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDD------RDHCAGS-PCGNGAACYTAQSDYY 536
C++ C D + + C C G++G C+ +C+ S C NG +C + D
Sbjct: 289 CSHADGC-DPVTGH-CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSC--SPEDGS 344
Query: 537 CHCAPGWTGKNCTQRAARD------RKTCSVLVEESERC--AEGMCANGGTCVREEGSWR 588
C CAPG+ G C + + C + V S C G+C C+
Sbjct: 345 CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE----CLPGFSGAL 400
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGT-CLPSALPPGWACGCREGRTGALCELS 647
D G C P + + C G G C
Sbjct: 401 CNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC--- 457
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVR 685
C C NG C G C C GWTG C R
Sbjct: 458 FHACS---CHNGASCSAEDG--ACHCTPGWTGLFCTQR 490
Score = 53.6 bits (123), Expect = 3e-06
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 15/94 (15%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEK--------PVCKE 214
+C Y+ C C ++ +C+P DG C PGW G +C + P C
Sbjct: 404 VCAGGYFGQDCAQLCSCANNG----TCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFH 459
Query: 215 GCHPTHGR-CD-RPGDCDCRPGWRGELCSQCQPY 246
C +G C G C C PGW G C+Q +P+
Sbjct: 460 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRKPH 493
Score = 33.9 bits (74), Expect = 2.9
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 629 PGWACG--CREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
PG C C G G C S D C PC +GG+C +G C C AG+ G+ C
Sbjct: 5 PGAVCAQPCPPGTFGQNC--SQD-C---PCHHGGQCDHVTG--QCHCTAGYMGDRC 52
>X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein.
Length = 2199
Score = 130 bits (314), Expect = 2e-29
Identities = 141/508 (27%), Positives = 178/508 (35%), Gaps = 85/508 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCK-HGYC-N 255
C PGW+G NC +P C CH GRC G C C G+ GE CSQ C G C N
Sbjct: 176 CEPGWKGPNCSEPECPGNCH-LRGRC-IDGQCICDDGFTGEDCSQLACPSDCNDQGKCVN 233
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPC-QHGGTCENTAPDQYFCRCAEGFSGVDCER 314
G C C + G D C PC + GTC + C C +GF+G DC +
Sbjct: 234 GV---CIC---FEGYAADCSREICPV--PCSEEHGTCVDG-----LCVCHDGFAGDDCNK 280
Query: 315 VDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
P C G C CD G+ G C C ++
Sbjct: 281 --------PLCLNNCYNRGRCVENECVCDEGFTG---EDCSELICPNDCFDRGRC---IN 326
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCV--------------NAAACNNT 418
G TC C +G+TG C + C T+G G CV A C+N
Sbjct: 327 G-TCYCEEGFTGEDCGKPT--CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNR 383
Query: 419 AGGYS--CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C C G+TG DC C C C+ + C C GY G CS
Sbjct: 384 GRCVDGRCECDDGFTGADC--GELKCPNGCSGHGRCV----NGQCVCDEGYTGEDCS--- 434
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
P C + G CV+ +C+C GF G +C D + C C
Sbjct: 435 QLRCPNDCHSRGRCVE----GKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM---- 483
Query: 537 CHCAPGWTGKNCTQR-AARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
C C G+TG++C R RD + V+ C +G G C E S
Sbjct: 484 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF--TGPDCA--ELSCPNDCHGQG 539
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
+ C C C EG TG C C S
Sbjct: 540 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC--GQHSC-PSD 596
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N G+CV G C C G++GE C+
Sbjct: 597 CNNLGQCVSG----RCICNEGYSGEDCS 620
Score = 126 bits (305), Expect = 3e-28
Identities = 113/413 (27%), Positives = 165/413 (39%), Gaps = 76/413 (18%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRC 223
+C + C+ P +D F C +G +C G+ G++C KP C CH T GRC
Sbjct: 299 VCDEGFTGEDCSELICP-NDCFDRGRCI-NGTCYCEEGFTGEDCGKPTCPHACH-TQGRC 355
Query: 224 DRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGILCDQDL--NYCG 280
+ G C C G+ G CS+ + C + G C C CD + G C + N C
Sbjct: 356 EE-GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR--CECDDGFTGADCGELKCPNGCS 412
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHGTCSLAGTTRGFT 339
H C +G C C EG++G DC ++ P C + G C G
Sbjct: 413 GHGRCVNGQ-----------CVCDEGYTGEDCSQLR---CPNDCHSRGRC-----VEG-K 452
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDV--DECS 397
C C++G+ G C C ++G C C DG+TG C + +CS
Sbjct: 453 CVCEQGFKGYDCSDMS---CPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRDCS 505
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
R G CV+ C C G+TG DC C C C++
Sbjct: 506 NR-------GLCVDG----------QCVCEDGFTGPDCAEL--SCPNDCHGQGRCVN--- 543
Query: 458 DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
C C G+ G+ C + P C G CVD +CIC GF+G +C H
Sbjct: 544 -GQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVD----GQCICHEGFTGLDCGQ---HS 592
Query: 518 AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
S C N C + + C C G++G++C++ + + + EE+ A
Sbjct: 593 CPSDCNNLGQCVSGR----CICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLA 641
Score = 122 bits (295), Expect = 5e-27
Identities = 118/409 (28%), Positives = 158/409 (38%), Gaps = 77/409 (18%)
Query: 170 YNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDC 229
Y C+ P H +C DG C G+ GD+C KP+C C+ GRC +C
Sbjct: 242 YAADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCY-NRGRCVE-NEC 298
Query: 230 DCRPGWRGELCSQCQPYPGC-KHGYC-NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH 287
C G+ GE CS+ C G C NG+ C C+ + G C + C C
Sbjct: 299 VCDEGFTGEDCSELICPNDCFDRGRCINGT---CYCEEGFTGEDCGKPT--C--PHACHT 351
Query: 288 GGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWG 347
G CE C C EGF+GVDC + C P C + + G C CD G+
Sbjct: 352 QGRCEEGQ-----CVCDEGFAGVDCS--EKRC-PADCHNRGRCVDG-----RCECDDGFT 398
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE--DVDECSGRSMTEGA 405
G C +G S C C +G+TG C++ ++C R
Sbjct: 399 GADCGEL-------KCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSR------ 445
Query: 406 LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAA 465
G CV C C G+ G DC C C C++ + C C
Sbjct: 446 -GRCVEG----------KCVCEQGFKGYDCSDM--SCPNDCHQHGRCVNGM----CVCDD 488
Query: 466 GYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
GY G C D PR C+N G CVD +C+C GF+G +C + C G G
Sbjct: 489 GYTGEDCR---DRQCPRDCSNRGLCVD----GQCVCEDGFTGPDCAE--LSCPNDCHGQG 539
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C Q C C G+ GK+C + + C RC +G C
Sbjct: 540 -RCVNGQ----CVCHEGFMGKDCKE------QRCPSDCHGQGRCVDGQC 577
Score = 120 bits (288), Expect = 3e-26
Identities = 139/499 (27%), Positives = 182/499 (36%), Gaps = 87/499 (17%)
Query: 190 CTPDGDKHCLPGWQGDNCEKPVCK-EGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPG 248
CT G CL G +P C G T G C C C PGW+G CS+ + PG
Sbjct: 140 CTA-GAGCCLQPATGRLDTRPFCSGRGNFSTEG-CG----CVCEPGWKGPNCSEPE-CPG 192
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS 308
H C CD + G +D + C G C N C C EG++
Sbjct: 193 NCHLRGRCIDGQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYA 243
Query: 309 GVDCERVDNPCAPQPCA--HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
DC R P PC+ HGTC + G C C G+ G CL+
Sbjct: 244 -ADCSR---EICPVPCSEEHGTC-VDG-----LCVCHDGFAGDDCNKPL-------CLNN 286
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDV--DECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
R C C +G+TG C+E + ++C R G C+N +C
Sbjct: 287 CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR-------GRCING----------TC 329
Query: 425 ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC 484
C G+TG DC C C C ++ C C G+AG CS + P C
Sbjct: 330 YCEEGFTGEDC--GKPTCPHACHTQGRC----EEGQCVCDEGFAGVDCS---EKRCPADC 380
Query: 485 TNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
N G CVD RC C GF+G +C + + C G+G C Q C C G+T
Sbjct: 381 HNRGRCVD----GRCECDDGFTGADCGELK--CPNGCSGHG-RCVNGQ----CVCDEGYT 429
Query: 545 GKNCTQ-RAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSX 603
G++C+Q R D + VE C +G G C + S
Sbjct: 430 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGF--KGYDC--SDMSCPNDCHQHGRCVNGMCV 485
Query: 604 XXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV 663
Q C L C C +G TG C +L + C GRCV
Sbjct: 486 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---AELSCPNDCHGQGRCV 542
Query: 664 GGSGWWMCECVAGWTGETC 682
G C C G+ G+ C
Sbjct: 543 NG----QCVCHEGFMGKDC 557
Score = 83.0 bits (196), Expect = 5e-15
Identities = 94/373 (25%), Positives = 129/373 (34%), Gaps = 51/373 (13%)
Query: 329 CSLAG--TTRGFTCTCDRGWGGXXXXXXX---XXXASGPCLHGASCRDHLDGFTCECADG 383
CS G +T G C C+ GW G G C+ G D DGFT E
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD--DGFTGEDCSQ 218
Query: 384 WTGPACAEDVDEC-SGRSMT-EGALGPC---VNAAACNNTAGGYS---CACLAGWTGRDC 435
P+ D +C +G + EG C + C+ G C C G+ G DC
Sbjct: 219 LACPSDCNDQGKCVNGVCICFEGYAADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDC 278
Query: 436 ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN 495
N C C + C++ C C G+ G CS + P C + G C++
Sbjct: 279 --NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELICPNDCFDRGRCIN--- 326
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
C C GF+G +C + C + C C Q C C G+ G +C++
Sbjct: 327 -GTCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEEGQ----CVCDEGFAGVDCSE----- 373
Query: 556 RKTCSVLVEESERCAEGMC-ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
K C RC +G C + G + G + +
Sbjct: 374 -KRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGED 432
Query: 615 XXQ--AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCE 672
Q C C C +G G C D+ + C GRCV G MC
Sbjct: 433 CSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNG----MCV 485
Query: 673 CVAGWTGETCAVR 685
C G+TGE C R
Sbjct: 486 CDDGYTGEDCRDR 498
>BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein
protein.
Length = 674
Score = 129 bits (311), Expect = 6e-29
Identities = 53/147 (36%), Positives = 75/147 (51%), Gaps = 9/147 (6%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 528 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 586
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 587 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 646
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGK 546
C NG C Q++ C C PG+TG+
Sbjct: 647 LTCYNGGNCTEFQTELKCMCRPGFTGE 673
Score = 120 bits (290), Expect = 2e-26
Identities = 53/135 (39%), Positives = 71/135 (52%), Gaps = 8/135 (5%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLHG C D+ +HC+C G++G+ C L++D+C PC +G C D + AY C C G+
Sbjct: 529 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCTCEPGY 587
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G NCE D D+C C NGA C + + Y C C +TGK C Q R +V E
Sbjct: 588 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ----SRLPSTVCGNE 643
Query: 566 SERCAEGMCANGGTC 580
C NGG C
Sbjct: 644 KTNLT---CYNGGNC 655
Score = 114 bits (275), Expect = 1e-24
Identities = 53/156 (33%), Positives = 77/156 (49%), Gaps = 17/156 (10%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 526 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS--------NPCIH-GNCSDRV 576
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTC---SLD 475
Y C C G+TG +CE ++D+C + QC +GATCI + + C C + G+ C L
Sbjct: 577 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 636
Query: 476 VDDCAPR----PCTNGGECVDLLNAYRCICPVGFSG 507
C C NGG C + +C+C GF+G
Sbjct: 637 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672
Score = 97.5 bits (232), Expect = 2e-19
Identities = 52/159 (32%), Positives = 68/159 (42%), Gaps = 9/159 (5%)
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTT 335
LN C ++ PC HGG CE+ Y C C G+SG CE + C PC HG CS
Sbjct: 521 LNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS--DRV 576
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED--V 393
+ CTC+ G+ G S C +GA+C H +G++C C +TG C +
Sbjct: 577 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 636
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
G T C N C C C G+TG
Sbjct: 637 STVCGNEKTNLT---CYNGGNCTEFQTELKCMCRPGFTG 672
Score = 86.6 bits (205), Expect = 4e-16
Identities = 40/111 (36%), Positives = 58/111 (52%), Gaps = 15/111 (13%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 516 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 574
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ Y+C C PG+TG NC + + C CANG TC+
Sbjct: 575 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCI 611
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 524 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 580
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 581 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 638
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C +G +C + C C G+TG
Sbjct: 639 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672
Score = 63.7 bits (148), Expect = 3e-09
Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 544 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 602
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDC--ERVDNPCAPQPCAHGTCSLAGTTRGF-- 338
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 603 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 660
Query: 339 --TCTCDRGWGG 348
C C G+ G
Sbjct: 661 ELKCMCRPGFTG 672
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 277 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 335
Query: 506 SG 507
+G
Sbjct: 336 NG 337
Score = 52.0 bits (119), Expect = 1e-05
Identities = 19/50 (38%), Positives = 26/50 (52%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G TG CE+ +D C S C NG C+ + + C C +TG+ C
Sbjct: 581 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 630
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 266 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 323
Query: 532 QSDYYC 537
+ C
Sbjct: 324 LQGFEC 329
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 532 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 588
Query: 679 GETCAVRV 686
G C V +
Sbjct: 589 GVNCEVDI 596
Score = 47.2 bits (107), Expect = 3e-04
Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 28/171 (16%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C +PC +G C S Y+C C GW+GK+ C + ++E C C +
Sbjct: 524 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKH-----------CELNIDE---CFSNPCIH 569
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G C ++ + G TC+ G++C C
Sbjct: 570 GN-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCAN----GATCISHT--NGYSCLCF 622
Query: 637 EGRTGALCE---LSLDLCGSSP----CRNGGRCVGGSGWWMCECVAGWTGE 680
TG C L +CG+ C NGG C C C G+TGE
Sbjct: 623 GNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGE 673
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 257 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 313
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 314 CPHGAQCQPVLQGFECIANAVFNGQS 339
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 519 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 559
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 274 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 324
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 325 QGFECIANAVFNGQ 338
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 270 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 325
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 326 GFECIANAVFNG 337
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 55 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 95
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 266 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 305
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 55 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 88
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 272 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 303
>BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 129 bits (311), Expect = 6e-29
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAPGWTGKNCTQRAARDRK 557
C+C P T + T+ RDR+
Sbjct: 207 CNCLPE-TVRRGTELWERDRE 226
Score = 124 bits (300), Expect = 1e-27
Identities = 75/217 (34%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Query: 253 YCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP-DQYFCRCAEGFSGVD 311
Y NG+ + C C + G C Q + C + CQ+GGTC A + CRCA GF+G D
Sbjct: 5 YHNGTGY-CKCPEGFLGEYC-QHRDPCEKNR-CQNGGTCVAQAMLGKATCRCASGFTGED 61
Query: 312 CE-RVDNPC-APQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
C+ +PC +PC +G TC + + CTC G+ G S PC +G++
Sbjct: 62 CQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWTDACL-SHPCANGST 119
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + F+C+C G+TG C DV+EC G C + C N G Y C CL
Sbjct: 120 CTTVANQFSCKCLTGFTGQKCETDVNECD-------IPGHCQHGGICLNLPGSYQCQCLQ 172
Query: 429 GWTGRDCETNVDDCT-GQCLHGATCIDLVD-DFHCAC 463
G+TG+ C++ C C++G TC D F C C
Sbjct: 173 GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 209
Score = 121 bits (292), Expect = 1e-26
Identities = 72/215 (33%), Positives = 96/215 (44%), Gaps = 28/215 (13%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C+C +G+ G C + D C G G CV A G +C C +G+TG DC+
Sbjct: 12 CKCPEGFLGEYC-QHRDPCEKNRCQNG--GTCVAQAML----GKATCRCASGFTGEDCQY 64
Query: 438 NVDD-C--TGQCLHGATCIDLV-DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ C + CL+G TC L D + C C G+ G+ C D C PC NG C +
Sbjct: 65 STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTV 123
Query: 494 LNAYRCICPVGFSGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
N + C C GF+G CE D + C C +G C Y C C G+TG+ C
Sbjct: 124 ANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCD--- 180
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
S+ V CA C NGGTC R+ G +
Sbjct: 181 -------SLYVP----CAPSPCVNGGTC-RQTGDF 203
Score = 102 bits (245), Expect = 6e-21
Identities = 59/174 (33%), Positives = 81/174 (46%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GG C+ GS++
Sbjct: 127 FSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGICLNLPGSYQ 167
Score = 101 bits (241), Expect = 2e-20
Identities = 67/221 (30%), Positives = 89/221 (40%), Gaps = 22/221 (9%)
Query: 227 GDCDCRPGWRGELCSQCQPYP--GCKH-GYCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++ G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRDCE 436
A PCVN C T + C CL R E
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPETVRRGTE 219
Score = 98.3 bits (234), Expect = 1e-19
Identities = 68/221 (30%), Positives = 87/221 (39%), Gaps = 27/221 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GG CL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGICLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210
Score = 69.7 bits (163), Expect = 5e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-terminal
like protein protein.
Length = 236
Score = 129 bits (311), Expect = 6e-29
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 363 CLHGASC--RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C +G +C + L TC CA G+TG C S PC+N C+ +
Sbjct: 34 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR------PCLNGGTCHMLSR 87
Query: 421 G-YSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C C G+TG++C+ D C C +G+TC + + F C C G+ G+ C DV++
Sbjct: 88 DTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 146
Query: 479 C-APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC-YTAQSDYY 536
C P C +GG C++L +Y+C C GF+G C+ CA SPC NG C T +
Sbjct: 147 CDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 206
Query: 537 CHCAPGWTGKNCTQRAARDRK 557
C+C P T + T+ RDR+
Sbjct: 207 CNCLPE-TVRRGTELWERDRE 226
Score = 124 bits (300), Expect = 1e-27
Identities = 75/217 (34%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Query: 253 YCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP-DQYFCRCAEGFSGVD 311
Y NG+ + C C + G C Q + C + CQ+GGTC A + CRCA GF+G D
Sbjct: 5 YHNGTGY-CKCPEGFLGEYC-QHRDPCEKNR-CQNGGTCVAQAMLGKATCRCASGFTGED 61
Query: 312 CE-RVDNPC-APQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
C+ +PC +PC +G TC + + CTC G+ G S PC +G++
Sbjct: 62 CQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWTDACL-SHPCANGST 119
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + F+C+C G+TG C DV+EC G C + C N G Y C CL
Sbjct: 120 CTTVANQFSCKCLTGFTGQKCETDVNECD-------IPGHCQHGGICLNLPGSYQCQCLQ 172
Query: 429 GWTGRDCETNVDDCT-GQCLHGATCIDLVD-DFHCAC 463
G+TG+ C++ C C++G TC D F C C
Sbjct: 173 GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 209
Score = 121 bits (292), Expect = 1e-26
Identities = 72/215 (33%), Positives = 96/215 (44%), Gaps = 28/215 (13%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C+C +G+ G C + D C G G CV A G +C C +G+TG DC+
Sbjct: 12 CKCPEGFLGEYC-QHRDPCEKNRCQNG--GTCVAQAML----GKATCRCASGFTGEDCQY 64
Query: 438 NVDD-C--TGQCLHGATCIDLV-DDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDL 493
+ C + CL+G TC L D + C C G+ G+ C D C PC NG C +
Sbjct: 65 STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTV 123
Query: 494 LNAYRCICPVGFSGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
N + C C GF+G CE D + C C +G C Y C C G+TG+ C
Sbjct: 124 ANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCD--- 180
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
S+ V CA C NGGTC R+ G +
Sbjct: 181 -------SLYVP----CAPSPCVNGGTC-RQTGDF 203
Score = 102 bits (245), Expect = 6e-21
Identities = 59/174 (33%), Positives = 81/174 (46%), Gaps = 22/174 (12%)
Query: 421 GYSCACLAGWTGRDCETNVDDCT-GQCLHGATCID--LVDDFHCACAAGYAGRTCSLDVD 477
GY C C G+ G C+ D C +C +G TC+ ++ C CA+G+ G C
Sbjct: 10 GY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS 67
Query: 478 D-C-APRPCTNGGECVDLL-NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C RPC NGG C L + Y C C VGF+G C+ D C PC NG+ C T +
Sbjct: 68 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 126
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+TG+ C D C + G C +GG C+ GS++
Sbjct: 127 FSCKCLTGFTGQKCET----DVNECDI---------PGHCQHGGICLNLPGSYQ 167
Score = 101 bits (241), Expect = 2e-20
Identities = 67/221 (30%), Positives = 89/221 (40%), Gaps = 22/221 (9%)
Query: 227 GDCDCRPGWRGELCSQCQPYP--GCKH-GYCNGSSW----DCTCDTNWGGILCDQDLNY- 278
G C C G+ GE C P C++ G C + C C + + G C ++
Sbjct: 10 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRG 337
C PC +GGTC + D Y C C GF+G +C+ D C PCA+G TC+
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQ-- 126
Query: 338 FTCTCDRGWGGXX-XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
F+C C G+ G G C HG C + + C+C G+TG C C
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPC 186
Query: 397 SGRSMTEGALGPCVNAAACNNTAG-GYSCACLAGWTGRDCE 436
A PCVN C T + C CL R E
Sbjct: 187 --------APSPCVNGGTCRQTGDFTFECNCLPETVRRGTE 219
Score = 98.3 bits (234), Expect = 1e-19
Identities = 68/221 (30%), Positives = 87/221 (39%), Gaps = 27/221 (12%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDH- 516
+C C G+ G C D C C NGG CV +L C C GF+G +C+ H
Sbjct: 11 YCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 517 CAGS-PCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
C S PC NG C+ D Y C C G+TGK C + ++ C C
Sbjct: 70 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC---------------QWTDACLSHPC 114
Query: 575 ANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACG 634
ANG TC + ++ Q GG CL LP + C
Sbjct: 115 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC---QHGGICLN--LPGSYQCQ 169
Query: 635 CREGRTGALCELSLDLCGSSPCRNGGRC-VGGSGWWMCECV 674
C +G TG C+ C SPC NGG C G + C C+
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 210
Score = 69.7 bits (163), Expect = 5e-11
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQ--SDYYCHCAPGWTGKNCTQRAARDR 556
C CP GF G C+ RD C + C NG C C CA G+TG++C +
Sbjct: 12 CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP- 69
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXX 616
C V C NGGTC R
Sbjct: 70 --CFV---------SRPCLNGGTCHMLS---RDTYECTCQVGFTGKECQWTDACLSHPCA 115
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG-SSPCRNGGRCVGGSGWWMCECVA 675
G TC + + ++C C G TG CE ++ C C++GG C+ G + C+C+
Sbjct: 116 N-GSTC--TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQ 172
Query: 676 GWTGETC 682
G+TG+ C
Sbjct: 173 GFTGQYC 179
Score = 66.1 bits (154), Expect = 6e-10
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 536 YCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXX 595
YC C G+ G+ C R + C + C NGGTCV + +
Sbjct: 11 YCKCPEGFLGEYCQHR---------------DPCEKNRCQNGGTCVAQAMLGKATCRCAS 55
Query: 596 XXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSP 655
D GGTC + + C C+ G TG C+ + D C S P
Sbjct: 56 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDT-YECTCQVGFTGKECQWT-DACLSHP 113
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
C NG C + + C+C+ G+TG+ C V+
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCETDVN 145
>AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 674
Score = 129 bits (311), Expect = 6e-29
Identities = 53/147 (36%), Positives = 75/147 (51%), Gaps = 9/147 (6%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC++ C + Y C+C GW+G+ CE N+D+C + C+HG C D V +HC C G
Sbjct: 528 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPG 586
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDR-------DHCAG 519
Y G C +D+D+C C NG C+ N Y C+C F+G C R +
Sbjct: 587 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 646
Query: 520 SPCGNGAACYTAQSDYYCHCAPGWTGK 546
C NG C Q++ C C PG+TG+
Sbjct: 647 LTCYNGGNCTEFQTELKCMCRPGFTGE 673
Score = 120 bits (290), Expect = 2e-26
Identities = 53/135 (39%), Positives = 71/135 (52%), Gaps = 8/135 (5%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLHG C D+ +HC+C G++G+ C L++D+C PC +G C D + AY C C G+
Sbjct: 529 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCTCEPGY 587
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G NCE D D+C C NGA C + + Y C C +TGK C Q R +V E
Sbjct: 588 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ----SRLPSTVCGNE 643
Query: 566 SERCAEGMCANGGTC 580
C NGG C
Sbjct: 644 KTNLT---CYNGGNC 655
Score = 114 bits (275), Expect = 1e-24
Identities = 53/156 (33%), Positives = 77/156 (49%), Gaps = 17/156 (10%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + C C GW+G C ++DEC PC++ C++
Sbjct: 526 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS--------NPCIH-GNCSDRV 576
Query: 420 GGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTC---SLD 475
Y C C G+TG +CE ++D+C + QC +GATCI + + C C + G+ C L
Sbjct: 577 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 636
Query: 476 VDDCAPR----PCTNGGECVDLLNAYRCICPVGFSG 507
C C NGG C + +C+C GF+G
Sbjct: 637 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672
Score = 97.5 bits (232), Expect = 2e-19
Identities = 52/159 (32%), Positives = 68/159 (42%), Gaps = 9/159 (5%)
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTT 335
LN C ++ PC HGG CE+ Y C C G+SG CE + C PC HG CS
Sbjct: 521 LNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS--DRV 576
Query: 336 RGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAED--V 393
+ CTC+ G+ G S C +GA+C H +G++C C +TG C +
Sbjct: 577 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 636
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
G T C N C C C G+TG
Sbjct: 637 STVCGNEKTNLT---CYNGGNCTEFQTELKCMCRPGFTG 672
Score = 86.6 bits (205), Expect = 4e-16
Identities = 40/111 (36%), Positives = 58/111 (52%), Gaps = 15/111 (13%)
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
T L ++ C PC +GG C D+ ++Y C CP+G+SG +CE + D C +PC +G C
Sbjct: 516 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 574
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ Y+C C PG+TG NC + + C CANG TC+
Sbjct: 575 RVAAYHCTCEPGYTGVNCE--------------VDIDNCQSHQCANGATCI 611
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 243 CQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P G C SS+ C+C W G C+ +++ C ++ PC HG + A Y
Sbjct: 524 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVA--AYH 580
Query: 301 CRCAEGFSGVDCE-RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXX-------XX 352
C C G++GV+CE +DN C CA+G ++ T G++C C + G
Sbjct: 581 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPST 638
Query: 353 XXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C +G +C + C C G+TG
Sbjct: 639 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672
Score = 63.7 bits (148), Expect = 3e-09
Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNYCGTH 282
C C GW G+ C +C P C HG C+ +++ CTC+ + G+ C+ D++ C +H
Sbjct: 544 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 602
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGFSGVDC--ERVDNPCAPQPCAHGTCSLAGTTRGF-- 338
+ C +G TC + + Y C C F+G C R+ + + TC G F
Sbjct: 603 Q-CANGATCISHT-NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 660
Query: 339 --TCTCDRGWGG 348
C C G+ G
Sbjct: 661 ELKCMCRPGFTG 672
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G C DDF C+C A +G+ C +V C PC +G +C +L + CI F
Sbjct: 277 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 335
Query: 506 SG 507
+G
Sbjct: 336 NG 337
Score = 52.0 bits (119), Expect = 1e-05
Identities = 19/50 (38%), Positives = 26/50 (52%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G TG CE+ +D C S C NG C+ + + C C +TG+ C
Sbjct: 581 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 630
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C+ D + C PC NGG C + + C CP SG CE+ + C SPC +GA C
Sbjct: 266 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPV 323
Query: 532 QSDYYC 537
+ C
Sbjct: 324 LQGFEC 329
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG C + + C C G +G CEL++D C S+PC + G C + C C G+T
Sbjct: 532 GGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYT 588
Query: 679 GETCAVRV 686
G C V +
Sbjct: 589 GVNCEVDI 596
Score = 47.2 bits (107), Expect = 3e-04
Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 28/171 (16%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C +PC +G C S Y+C C GW+GK+ C + ++E C C +
Sbjct: 524 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKH-----------CELNIDE---CFSNPCIH 569
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G C ++ + G TC+ G++C C
Sbjct: 570 GN-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCAN----GATCISHT--NGYSCLCF 622
Query: 637 EGRTGALCE---LSLDLCGSSP----CRNGGRCVGGSGWWMCECVAGWTGE 680
TG C L +CG+ C NGG C C C G+TGE
Sbjct: 623 GNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGE 673
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQ 445
P C+G + + PC N C++ +SC+C A +G+ CE V C
Sbjct: 257 PVLVNVTQGCAGDNSCKS--NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 313
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRT 471
C HGA C ++ F C A + G++
Sbjct: 314 CPHGAQCQPVLQGFECIANAVFNGQS 339
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/41 (36%), Positives = 24/41 (58%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
L L++C S+PC +GG C + C C GW+G+ C + +
Sbjct: 519 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 559
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PC +G C D F+C C +G AC E+V C PC + A C
Sbjct: 274 SNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC--------GFSPCPHGAQCQPVL 324
Query: 420 GGYSCACLAGWTGR 433
G+ C A + G+
Sbjct: 325 QGFECIANAVFNGQ 338
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C ++ PC +GG C + D + C C SG CE V C PC HG +
Sbjct: 270 NSCKSN-PCHNGGVCHSRW-DDFSCSCPALTSGKACEEV-QWCGFSPCPHG-AQCQPVLQ 325
Query: 337 GFTCTCDRGWGG 348
GF C + + G
Sbjct: 326 GFECIANAVFNG 337
Score = 37.9 bits (84), Expect = 0.18
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG 519
D C +PC + G C++L +Y+C C + G NC R++ AG
Sbjct: 55 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL--REYVAG 95
Score = 37.1 bits (82), Expect = 0.31
Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C D C +PC NG C++ D+ C C +GK C +
Sbjct: 266 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 305
Score = 32.7 bits (71), Expect = 6.7
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 649 DLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
D C S PC++ GRC+ + C+C + G C
Sbjct: 55 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 88
Score = 32.3 bits (70), Expect = 8.8
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C S+PC NGG C + C C A +G+ C
Sbjct: 272 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 303
>AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain
containing protein protein.
Length = 199
Score = 128 bits (308), Expect = 1e-28
Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 18/177 (10%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA--GGYSCACLAGWTGRDC 435
CEC GWTG C+E+++EC PC+N C+ + G + C C +TG+ C
Sbjct: 1 CECTSGWTGQNCSEEINECDS--------DPCMNGGLCHESTIPGQFVCLCPPLYTGQFC 52
Query: 436 ETNVDDCT---GQCLHGATCIDLVD-DFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV 491
+ C C + +TC+ LVD + HC C + G+ C +DV DC C + G+C
Sbjct: 53 HQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE 112
Query: 492 DLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
D++N +R GFSG+ CE + + C+ PC N C + ++C+C P + G C
Sbjct: 113 DMVNNFR----PGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 165
Score = 123 bits (296), Expect = 4e-27
Identities = 66/209 (31%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH-LDG-FTCECADGWTGPACAEDVDECS 397
C C GW G S PC++G C + + G F C C +TG C + + C
Sbjct: 1 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC- 59
Query: 398 GRSMTEGALGPCVNAAACNNTA-GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDL 455
+ PC N + C C C + G++CE +V DC C C D+
Sbjct: 60 -----DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM 114
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD 515
V++F G++G C +++++C+ PC N G CVDL N + C C + G CE D +
Sbjct: 115 VNNFR----PGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVN 170
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWT 544
C SPC + C Y C CAPG+T
Sbjct: 171 KCKISPCLDEENCVYRTDGYNCLCAPGYT 199
Score = 103 bits (246), Expect = 4e-21
Identities = 59/211 (27%), Positives = 89/211 (42%), Gaps = 17/211 (8%)
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC-ENTAPDQYFCRCAEGFSGVDCERVDNPC 319
C C + W G C +++N C + +PC +GG C E+T P Q+ C C ++G C + N C
Sbjct: 1 CECTSGWTGQNCSEEINECDS-DPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 59
Query: 320 --APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
PC + + LA C C + G C C D ++ F
Sbjct: 60 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNF- 118
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
G++G C +++ECS PC N C + + C C + G CE
Sbjct: 119 ---RPGFSGSLCEIEINECSSE--------PCKNNGTCVDLTNRFFCNCEPEYHGPFCEL 167
Query: 438 NVDDC-TGQCLHGATCIDLVDDFHCACAAGY 467
+V+ C CL C+ D ++C CA GY
Sbjct: 168 DVNKCKISPCLDEENCVYRTDGYNCLCAPGY 198
Score = 99.5 bits (237), Expect = 5e-20
Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 22/212 (10%)
Query: 229 CDCRPGWRGELCS----QCQPYPGCKHGYCNGSS----WDCTCDTNWGGILCDQDLNYCG 280
C+C GW G+ CS +C P G C+ S+ + C C + G C Q N C
Sbjct: 1 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60
Query: 281 -THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFT 339
H PC++ TC C C E F G +CE +D + C +C G
Sbjct: 61 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCE-ID----VKDCLFLSCQDYGDCEDMV 115
Query: 340 CTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR 399
G+ G +S PC + +C D + F C C + GP C DV++C
Sbjct: 116 NNFRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK-- 173
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ PC++ C GY+C C G+T
Sbjct: 174 ------ISPCLDEENCVYRTDGYNCLCAPGYT 199
Score = 82.2 bits (194), Expect = 8e-15
Identities = 58/223 (26%), Positives = 90/223 (40%), Gaps = 29/223 (13%)
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVD--LLNAYRCICPVGFSGTNCEDDRDHC- 517
C C +G+ G+ CS ++++C PC NGG C + + + C+CP ++G C + C
Sbjct: 1 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60
Query: 518 -AGSPCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
+PC N + C ++ +C C + GKNC D K C L C
Sbjct: 61 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEI----DVKDCLFL----------SCQ 106
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+ G C ++R S + GTC+ L + C C
Sbjct: 107 DYGDCEDMVNNFRPGFSG--------SLCEIEINECSSEPCKNNGTCVD--LTNRFFCNC 156
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G CEL ++ C SPC + CV + + C C G+T
Sbjct: 157 EPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYT 199
Score = 81.4 bits (192), Expect = 1e-14
Identities = 50/164 (30%), Positives = 74/164 (45%), Gaps = 24/164 (14%)
Query: 424 CACLAGWTGRDCETNVDDCTGQ-CLHGATCID--LVDDFHCACAAGYAGRTCS--LDVDD 478
C C +GWTG++C +++C C++G C + + F C C Y G+ C ++ D
Sbjct: 1 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60
Query: 479 CAPRPCTNGGECVDLLNAYR-CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
PC N C+ L++A + CIC F G NCE D C C + C D
Sbjct: 61 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC----EDMVN 116
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCV 581
+ PG++G C +E +E C+ C N GTCV
Sbjct: 117 NFRPGFSGSLCE-------------IEINE-CSSEPCKNNGTCV 146
Score = 49.2 bits (112), Expect = 7e-05
Identities = 19/52 (36%), Positives = 30/52 (57%)
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
R G +G+LCE+ ++ C S PC+N G CV + + C C + G C + V+
Sbjct: 119 RPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVN 170
Score = 45.6 bits (103), Expect = 9e-04
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS--GWWMCECVAGWTGETCAVR 685
C C G TG C ++ C S PC NGG C + G ++C C +TG+ C R
Sbjct: 1 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQR 55
Score = 39.9 bits (89), Expect = 0.044
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 3/71 (4%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCG--SSPCRNGGRCVG-GSGWWMCECVA 675
GG C S +P + C C TG C +LC +PCRN C+ C C
Sbjct: 27 GGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICRE 86
Query: 676 GWTGETCAVRV 686
+ G+ C + V
Sbjct: 87 EFEGKNCEIDV 97
>DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein.
Length = 231
Score = 127 bits (307), Expect = 2e-28
Identities = 56/154 (36%), Positives = 73/154 (47%), Gaps = 8/154 (5%)
Query: 408 PCVNAAACNNTAGG-YSCACLAGWTGRDCETNVDDCT---GQCLHGATCID---LVDDFH 460
PC N C + G Y C+C G++G+DC+ C C HG TC+D
Sbjct: 9 PCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHAS 68
Query: 461 CACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C C G++G C + + C P PC N G C D+ +RC CP GF C +CA S
Sbjct: 69 CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASS 128
Query: 521 PCGNGAACYT-AQSDYYCHCAPGWTGKNCTQRAA 553
PC NG C Q Y C C P +TG C ++ A
Sbjct: 129 PCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRA 162
Score = 94.3 bits (224), Expect = 2e-18
Identities = 53/166 (31%), Positives = 67/166 (40%), Gaps = 14/166 (8%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAH-GTC-S 330
D+ C + PC + GTC + Y C CA G+SG DC++ D PC PC H GTC
Sbjct: 1 DVRACSS-APCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVD 59
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACA 390
G +C C G+ G PC + C D F C C G+ C+
Sbjct: 60 DEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCS 119
Query: 391 EDVDECSGRSMTEGALGPCVNAAAC-NNTAGGYSCACLAGWTGRDC 435
V C A PC N C +T Y C C +TG C
Sbjct: 120 RPVTNC--------ASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 157
Score = 94.3 bits (224), Expect = 2e-18
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 20/143 (13%)
Query: 446 CLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPR--PCTNGGECVD---LLNAYRC 499
C + TC+ L D + C+CA GY+G+ C C PC +GG CVD + C
Sbjct: 10 CANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASC 69
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
+CP GFSG CE + C +PC N C D+ C C G+ K C++
Sbjct: 70 LCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTN----- 124
Query: 560 SVLVEESERCAEGMCANGGTCVR 582
CA C NGGTC++
Sbjct: 125 ---------CASSPCQNGGTCLQ 138
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/126 (30%), Positives = 50/126 (39%), Gaps = 13/126 (10%)
Query: 228 DCDCRPGWRGELC-----------SQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDL 276
+C C PG+ G+ C S CQ C S C C + G C+
Sbjct: 25 ECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVA 84
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTR 336
N C T PC++ G C + D + CRC GF C R CA PC +G L T
Sbjct: 85 NSC-TPNPCENDGVCTDIGGD-FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQV 142
Query: 337 GFTCTC 342
+ C C
Sbjct: 143 SYECLC 148
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/176 (29%), Positives = 65/176 (36%), Gaps = 25/176 (14%)
Query: 475 DVDDCAPRPCTNGGECVDLLNA-YRCICPVGFSGTNCEDDRDHCA--GSPCGNGAACYTA 531
DV C+ PC N G CV L + Y C C G+SG +C+ C GSPC +G C
Sbjct: 1 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD 60
Query: 532 Q---SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ S C C PG++G C +V S C C N G C G +R
Sbjct: 61 EGRASHASCLCPPGFSGNFCE------------IVANS--CTPNPCENDGVCTDIGGDFR 106
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
D Q GGTCL + C C+ TG C
Sbjct: 107 ----CRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHT-QVSYECLCKPEFTGLTC 157
Score = 67.3 bits (157), Expect = 3e-10
Identities = 46/152 (30%), Positives = 61/152 (40%), Gaps = 27/152 (17%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK---------PVCKEG--CHPTHGRCDRP 226
C DD G Y C+ C PG+ G +C+K C+ G C GR
Sbjct: 16 CVSLDD--GLYECS------CAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASH- 66
Query: 227 GDCDCRPGWRGELC----SQCQPYPGCKHGYCN--GSSWDCTCDTNWGGILCDQDLNYCG 280
C C PG+ G C + C P P G C G + C C + C + + C
Sbjct: 67 ASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCA 126
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+ PCQ+GGTC Y C C F+G+ C
Sbjct: 127 S-SPCQNGGTCLQHTQVSYECLCKPEFTGLTC 157
Score = 65.7 bits (153), Expect = 8e-10
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 17/168 (10%)
Query: 517 CAGSPCGNGAACYTAQSDYY-CHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C+ +PC N C + Y C CAPG++GK+C +K ++ S C
Sbjct: 5 CSSAPCANNGTCVSLDDGLYECSCAPGYSGKDC------QKKDGPCVINGSP------CQ 52
Query: 576 NGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGC 635
+GGTCV +EG + + G C + + + C C
Sbjct: 53 HGGTCVDDEGR-ASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC--TDIGGDFRCRC 109
Query: 636 REGRTGALCELSLDLCGSSPCRNGGRCVGGSG-WWMCECVAGWTGETC 682
G C + C SSPC+NGG C+ + + C C +TG TC
Sbjct: 110 PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 157
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 569 CAEGMCANGGTCVR-EEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSAL 627
C+ CAN GTCV ++G + D Q GGTC+
Sbjct: 5 CSSAPCANNGTCVSLDDGLYECSCAPGYSGK--DCQKKDGPCVINGSPCQHGGTCVDDEG 62
Query: 628 PPGWA-CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
A C C G +G CE+ + C +PC N G C G + C C AG+ +TC+
Sbjct: 63 RASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCS 119
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 127 bits (307), Expect = 2e-28
Identities = 132/447 (29%), Positives = 177/447 (39%), Gaps = 74/447 (16%)
Query: 188 YSCTPDGDKHCLPGWQGDNC-EKPVCKEGCHP-THGRCDR-PGD--CDCRPGWR-GELCS 241
Y+C D P QG C + C+ P GRC+ PG C C PG+R G +
Sbjct: 568 YTCACDSGFRLSP--QGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAA 625
Query: 242 QCQPY-------PGCKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHG 288
+C P C G C + S+ C C + G C QD++ C T P G
Sbjct: 626 ECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC-TQSPGLCG 683
Query: 289 -GTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAHGTCSLAGTTRGFTCTC--- 342
G C+N P + C C GF G CE + CA P PC G C T F C C
Sbjct: 684 RGACKNL-PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD--NTAGSFHCACPAG 740
Query: 343 --DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW----TGPACAEDVDEC 396
RG G + PC +G C + F C C G+ G C EDVDEC
Sbjct: 741 FRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNAAGSEC-EDVDEC 798
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRDCETNVDDCTG---QCLHGAT 451
G C N+ G + C AC +G R T+VD+C+ C
Sbjct: 799 ENHLACPG--------QECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGH 850
Query: 452 CIDLVDDFHCACAAGY---AGR--TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF 505
C + F C+CA GY +GR C+ DV++C C GEC++ ++ C C G+
Sbjct: 851 CTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAPGY 909
Query: 506 ----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
G +C D D C+ C + C C PG RA D +C +
Sbjct: 910 RPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPG-------HRAGPDLASC-L 960
Query: 562 LVEESERCAEGMCANGGTCVREEGSWR 588
V+E +C + C GS+R
Sbjct: 961 DVDECRERGPALCGS-QRCENSPGSYR 986
Score = 125 bits (302), Expect = 7e-28
Identities = 112/386 (29%), Positives = 146/386 (37%), Gaps = 58/386 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG 375
PQ C G C G+TC CD G+ G PC G C +
Sbjct: 553 PQVCGPGRC--ISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 609
Query: 376 FTCECADGW-TGPACAE--DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT- 431
F C C G+ GP AE DVDEC + P + C NT G + C C AG+
Sbjct: 610 FRCVCGPGFRAGPRAAECLDVDECH-------RVPPPCDLGRCENTPGSFLCVCPAGYQA 662
Query: 432 ---GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRP 483
G C+ +VD+CT G C GA C +L F C C AG+ G C DVD+CA P P
Sbjct: 663 APHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 720
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS--PCGNGAACYTAQSDYYC 537
C G C + ++ C CP GF G C+ D D CA S PC G C + + C
Sbjct: 721 C-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQC 777
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+ AA C E+ + C + G CV GS++
Sbjct: 778 VCPMGF-----QPNAAGSE--C----EDVDECENHLACPGQECVNSPGSFQCRACPSGHH 826
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR------EGRTGALCELSLDLC 651
G C + + C C GR G +++ L
Sbjct: 827 LHRGRCTDVDECSSGAPPCGPHGHC--TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLE 884
Query: 652 GSSPCRNGGRCVGGSGWWMCECVAGW 677
G C G C+ G + C C G+
Sbjct: 885 GDF-CFPHGECLNTDGSFACTCAPGY 909
Score = 116 bits (280), Expect = 3e-25
Identities = 139/444 (31%), Positives = 180/444 (40%), Gaps = 81/444 (18%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH-GRCDRPGD---CDCRPGWR----GELCS---QC- 243
C G++G CE+ V C + P GRCD C C G+R G C +C
Sbjct: 698 CPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 757
Query: 244 QPYPGCKHGYCNGS--SWDCTC----DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+ P C +G C + S+ C C N G C+ D++ C H C G C N+ P
Sbjct: 758 RSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECE-DVDECENHLACP-GQECVNS-PG 814
Query: 298 QYFCR-CAEG--FSGVDCERVDN-PCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ CR C G C VD PC HG C+ T F C+C G+
Sbjct: 815 SFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGYRAPSGR 872
Query: 353 XXXXXXASGPCLHGASCRDH-----LDG-FTCECADGWT-GPACAE--DVDECSGRSMTE 403
+ CL G C H DG F C CA G+ GP A DVDECS + +
Sbjct: 873 PGPCADVN-ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 931
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGW-TGRDCET--NVDDCT--GQCLHGAT-CIDLVD 457
+ C NT G + C C G G D + +VD+C G L G+ C +
Sbjct: 932 SGI--------CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 983
Query: 458 DFHCA--CAAGY-AGR--TCSLDVDDC---APRPCTNGGECVDLLNAYRCI--CPVGFS- 506
+ C C GY AG TC DVD+C P C C + +YRC C G+
Sbjct: 984 SYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQP 1041
Query: 507 --GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLV 563
G C+D D C S CG A C + C C G+ G ARD + C V V
Sbjct: 1042 TPGGGCQDV-DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG-------ARDGRHC-VDV 1092
Query: 564 EESERCAEGMCANGGTCVREEGSW 587
E E +G+C C EGS+
Sbjct: 1093 NECE-TLQGVC-GAALCENVEGSF 1114
Score = 64.1 bits (149), Expect = 2e-09
Identities = 78/272 (28%), Positives = 102/272 (37%), Gaps = 40/272 (14%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHGRC---DRPGDCDCRPGWR---- 236
G + C+ G G + C EG C P HG C D C C PG+R
Sbjct: 856 GSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPR 914
Query: 237 GELC---SQCQPYPGCKHGYCNGS--SWDCTCDTNW--GGILCD-QDLNYCGTHEPCQHG 288
G C +C C+ G C + S++C C G L D++ C P G
Sbjct: 915 GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG 974
Query: 289 GT-CENTAPDQYFC--RCAEGF-SGVD--CERVDN--PCAPQPCAHGTCSLAGTTRGFTC 340
CEN+ P Y C C G+ +G + C+ VD P+ C C T + C
Sbjct: 975 SQRCENS-PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCE--NTPGSYRC 1031
Query: 341 T--CDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
T CD G+ GG S H A C++ F C C G+ G A D
Sbjct: 1032 TPACDPGYQPTPGGGCQDVDECRNRSFCGAH-AVCQNLPGSFQCLCDQGYEG---ARDGR 1087
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C + E G C AA C N G + C C
Sbjct: 1088 HCVDVNECETLQGVC-GAALCENVEGSFLCVC 1118
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 438 NVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSL---DVDDCAPR-PCTNGGEC 490
+VD+C Q C++ + C C+ GY T L D D+CA P GG C
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312
Query: 491 VDLLNAYRCIC 501
V+ + +Y C C
Sbjct: 1313 VNTVGSYHCTC 1323
Score = 44.4 bits (100), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 10/72 (13%)
Query: 363 CLHGASCRDHLDGFTCECADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C +G R +GFTC C DG+ T AC D++EC E A CVNA C NT
Sbjct: 1543 CTNGRCVRVP-EGFTCRCFDGYRLDMTRMACV-DINECDE---AEAASPLCVNAR-CLNT 1596
Query: 419 AGGYSCACLAGW 430
G + C C G+
Sbjct: 1597 DGSFRCICRPGF 1608
Score = 41.9 bits (94), Expect = 0.011
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 412 AAACNNTAGGYSCACLAGW---TGR-DCETNVDDCTGQ--CLHGATCIDLVDDFHCAC 463
+ C NTA GYSC C G+ T R +C N D+C + G C++ V +HC C
Sbjct: 1267 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 40.3 bits (90), Expect = 0.033
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 11/80 (13%)
Query: 446 CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDC----APRPCTNGGECVDLLNAYR 498
C +G C+ + + F C C GY R +D+++C A P C++ ++R
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1601
Query: 499 CICPVGFSGTNCEDDRDHCA 518
CIC GF+ T+ HCA
Sbjct: 1602 CICRPGFAPTH---QPHHCA 1618
Score = 38.3 bits (85), Expect = 0.13
Identities = 42/145 (28%), Positives = 51/145 (35%), Gaps = 24/145 (16%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA 468
C N A N T C GW G C + C G A L C GY
Sbjct: 1193 CDNILARNVTWQECCCTVGEGW-GSGCR--IQQCPGT--ETAEYQSL-----CPHGRGYL 1242
Query: 469 GRTCSL----DVDDCA---PRPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHC 517
+ L DVD+C + C +G CV+ Y C C G+ C D+ D C
Sbjct: 1243 APSGDLSLRRDVDECQLFRDQVCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DEC 1300
Query: 518 AGS-PCGNGAACYTAQSDYYCHCAP 541
A P G C Y+C C P
Sbjct: 1301 ADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 37.1 bits (82), Expect = 0.31
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C G+ +C DVD+CA GEC + Y C+CP GF
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 387
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 303 CAEGFSGVD--CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
C GF V+ CE VD C HG C A T G+TC C G+
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGEC--ANTRGGYTCVCPDGF 387
Score = 34.3 bits (75), Expect = 2.2
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 620 GTCLPSALPPGWACGCREG---RTGALCELSLDLCGSS-PCRNGGRCVGGSGWWMCEC 673
G C+ +A PG++C C G T L + D C P GGRCV G + C C
Sbjct: 1268 GVCVNTA--PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 32.7 bits (71), Expect = 6.7
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 3/45 (6%)
Query: 501 CPVGFSGTN--CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
CP GF N CED + G C +G C + Y C C G+
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGE-CANTRGGYTCVCPDGF 387
Score = 32.7 bits (71), Expect = 6.7
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 19/95 (20%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C G C + G++C C++G+ T D DEC+ P C NT
Sbjct: 1265 CKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE-------PACEGGRCVNTV 1316
Query: 420 GGYSCAC----LAGWTGRDCETN----VDDCTGQC 446
G Y C C + + R C +N +DD G C
Sbjct: 1317 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVC 1351
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 127 bits (307), Expect = 2e-28
Identities = 132/447 (29%), Positives = 177/447 (39%), Gaps = 74/447 (16%)
Query: 188 YSCTPDGDKHCLPGWQGDNC-EKPVCKEGCHP-THGRCDR-PGD--CDCRPGWR-GELCS 241
Y+C D P QG C + C+ P GRC+ PG C C PG+R G +
Sbjct: 501 YTCACDSGFRLSP--QGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAA 558
Query: 242 QCQPY-------PGCKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHG 288
+C P C G C + S+ C C + G C QD++ C T P G
Sbjct: 559 ECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC-TQSPGLCG 616
Query: 289 -GTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAHGTCSLAGTTRGFTCTC--- 342
G C+N P + C C GF G CE + CA P PC G C T F C C
Sbjct: 617 RGACKNL-PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD--NTAGSFHCACPAG 673
Query: 343 --DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW----TGPACAEDVDEC 396
RG G + PC +G C + F C C G+ G C EDVDEC
Sbjct: 674 FRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNAAGSEC-EDVDEC 731
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRDCETNVDDCTG---QCLHGAT 451
G C N+ G + C AC +G R T+VD+C+ C
Sbjct: 732 ENHLACPG--------QECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGH 783
Query: 452 CIDLVDDFHCACAAGY---AGR--TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF 505
C + F C+CA GY +GR C+ DV++C C GEC++ ++ C C G+
Sbjct: 784 CTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAPGY 842
Query: 506 ----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
G +C D D C+ C + C C PG RA D +C +
Sbjct: 843 RPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPG-------HRAGPDLASC-L 893
Query: 562 LVEESERCAEGMCANGGTCVREEGSWR 588
V+E +C + C GS+R
Sbjct: 894 DVDECRERGPALCGS-QRCENSPGSYR 919
Score = 125 bits (302), Expect = 7e-28
Identities = 112/386 (29%), Positives = 146/386 (37%), Gaps = 58/386 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG 375
PQ C G C G+TC CD G+ G PC G C +
Sbjct: 486 PQVCGPGRC--ISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 542
Query: 376 FTCECADGW-TGPACAE--DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT- 431
F C C G+ GP AE DVDEC + P + C NT G + C C AG+
Sbjct: 543 FRCVCGPGFRAGPRAAECLDVDECH-------RVPPPCDLGRCENTPGSFLCVCPAGYQA 595
Query: 432 ---GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRP 483
G C+ +VD+CT G C GA C +L F C C AG+ G C DVD+CA P P
Sbjct: 596 APHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 653
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS--PCGNGAACYTAQSDYYC 537
C G C + ++ C CP GF G C+ D D CA S PC G C + + C
Sbjct: 654 C-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQC 710
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+ AA C E+ + C + G CV GS++
Sbjct: 711 VCPMGF-----QPNAAGSE--C----EDVDECENHLACPGQECVNSPGSFQCRACPSGHH 759
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR------EGRTGALCELSLDLC 651
G C + + C C GR G +++ L
Sbjct: 760 LHRGRCTDVDECSSGAPPCGPHGHC--TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLE 817
Query: 652 GSSPCRNGGRCVGGSGWWMCECVAGW 677
G C G C+ G + C C G+
Sbjct: 818 GDF-CFPHGECLNTDGSFACTCAPGY 842
Score = 116 bits (280), Expect = 3e-25
Identities = 139/444 (31%), Positives = 180/444 (40%), Gaps = 81/444 (18%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH-GRCDRPGD---CDCRPGWR----GELCS---QC- 243
C G++G CE+ V C + P GRCD C C G+R G C +C
Sbjct: 631 CPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 690
Query: 244 QPYPGCKHGYCNGS--SWDCTC----DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+ P C +G C + S+ C C N G C+ D++ C H C G C N+ P
Sbjct: 691 RSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECE-DVDECENHLACP-GQECVNS-PG 747
Query: 298 QYFCR-CAEG--FSGVDCERVDN-PCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ CR C G C VD PC HG C+ T F C+C G+
Sbjct: 748 SFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGYRAPSGR 805
Query: 353 XXXXXXASGPCLHGASCRDH-----LDG-FTCECADGWT-GPACAE--DVDECSGRSMTE 403
+ CL G C H DG F C CA G+ GP A DVDECS + +
Sbjct: 806 PGPCADVN-ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 864
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGW-TGRDCET--NVDDCT--GQCLHGAT-CIDLVD 457
+ C NT G + C C G G D + +VD+C G L G+ C +
Sbjct: 865 SGI--------CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 916
Query: 458 DFHCA--CAAGY-AGR--TCSLDVDDC---APRPCTNGGECVDLLNAYRCI--CPVGFS- 506
+ C C GY AG TC DVD+C P C C + +YRC C G+
Sbjct: 917 SYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQP 974
Query: 507 --GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLV 563
G C+D D C S CG A C + C C G+ G ARD + C V V
Sbjct: 975 TPGGGCQDV-DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG-------ARDGRHC-VDV 1025
Query: 564 EESERCAEGMCANGGTCVREEGSW 587
E E +G+C C EGS+
Sbjct: 1026 NECE-TLQGVC-GAALCENVEGSF 1047
Score = 64.1 bits (149), Expect = 2e-09
Identities = 78/272 (28%), Positives = 102/272 (37%), Gaps = 40/272 (14%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHGRC---DRPGDCDCRPGWR---- 236
G + C+ G G + C EG C P HG C D C C PG+R
Sbjct: 789 GSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPR 847
Query: 237 GELC---SQCQPYPGCKHGYCNGS--SWDCTCDTNW--GGILCD-QDLNYCGTHEPCQHG 288
G C +C C+ G C + S++C C G L D++ C P G
Sbjct: 848 GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG 907
Query: 289 GT-CENTAPDQYFC--RCAEGF-SGVD--CERVDN--PCAPQPCAHGTCSLAGTTRGFTC 340
CEN+ P Y C C G+ +G + C+ VD P+ C C T + C
Sbjct: 908 SQRCENS-PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCE--NTPGSYRC 964
Query: 341 T--CDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
T CD G+ GG S H A C++ F C C G+ G A D
Sbjct: 965 TPACDPGYQPTPGGGCQDVDECRNRSFCGAH-AVCQNLPGSFQCLCDQGYEG---ARDGR 1020
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C + E G C AA C N G + C C
Sbjct: 1021 HCVDVNECETLQGVC-GAALCENVEGSFLCVC 1051
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 438 NVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSL---DVDDCAPR-PCTNGGEC 490
+VD+C Q C++ + C C+ GY T L D D+CA P GG C
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
Query: 491 VDLLNAYRCIC 501
V+ + +Y C C
Sbjct: 1246 VNTVGSYHCTC 1256
Score = 44.4 bits (100), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 10/72 (13%)
Query: 363 CLHGASCRDHLDGFTCECADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C +G R +GFTC C DG+ T AC D++EC E A CVNA C NT
Sbjct: 1476 CTNGRCVRVP-EGFTCRCFDGYRLDMTRMACV-DINECDE---AEAASPLCVNAR-CLNT 1529
Query: 419 AGGYSCACLAGW 430
G + C C G+
Sbjct: 1530 DGSFRCICRPGF 1541
Score = 41.9 bits (94), Expect = 0.011
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 412 AAACNNTAGGYSCACLAGW---TGR-DCETNVDDCTGQ--CLHGATCIDLVDDFHCAC 463
+ C NTA GYSC C G+ T R +C N D+C + G C++ V +HC C
Sbjct: 1200 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 40.3 bits (90), Expect = 0.033
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 11/80 (13%)
Query: 446 CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDC----APRPCTNGGECVDLLNAYR 498
C +G C+ + + F C C GY R +D+++C A P C++ ++R
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1534
Query: 499 CICPVGFSGTNCEDDRDHCA 518
CIC GF+ T+ HCA
Sbjct: 1535 CICRPGFAPTH---QPHHCA 1551
Score = 38.3 bits (85), Expect = 0.13
Identities = 42/145 (28%), Positives = 51/145 (35%), Gaps = 24/145 (16%)
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA 468
C N A N T C GW G C + C G A L C GY
Sbjct: 1126 CDNILARNVTWQECCCTVGEGW-GSGCR--IQQCPGT--ETAEYQSL-----CPHGRGYL 1175
Query: 469 GRTCSL----DVDDCA---PRPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHC 517
+ L DVD+C + C +G CV+ Y C C G+ C D+ D C
Sbjct: 1176 APSGDLSLRRDVDECQLFRDQVCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DEC 1233
Query: 518 AGS-PCGNGAACYTAQSDYYCHCAP 541
A P G C Y+C C P
Sbjct: 1234 ADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 37.1 bits (82), Expect = 0.31
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C G+ +C DVD+CA GEC + Y C+CP GF
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 320
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 303 CAEGFSGVD--CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
C GF V+ CE VD C HG C A T G+TC C G+
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGEC--ANTRGGYTCVCPDGF 320
Score = 34.3 bits (75), Expect = 2.2
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 620 GTCLPSALPPGWACGCREG---RTGALCELSLDLCGSS-PCRNGGRCVGGSGWWMCEC 673
G C+ +A PG++C C G T L + D C P GGRCV G + C C
Sbjct: 1201 GVCVNTA--PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 32.7 bits (71), Expect = 6.7
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 3/45 (6%)
Query: 501 CPVGFSGTN--CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
CP GF N CED + G C +G C + Y C C G+
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGE-CANTRGGYTCVCPDGF 320
Score = 32.7 bits (71), Expect = 6.7
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 19/95 (20%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C G C + G++C C++G+ T D DEC+ P C NT
Sbjct: 1198 CKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE-------PACEGGRCVNTV 1249
Query: 420 GGYSCAC----LAGWTGRDCETN----VDDCTGQC 446
G Y C C + + R C +N +DD G C
Sbjct: 1250 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVC 1284
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 126 bits (305), Expect = 3e-28
Identities = 131/447 (29%), Positives = 177/447 (39%), Gaps = 74/447 (16%)
Query: 188 YSCTPDGDKHCLPGWQGDNC-EKPVCKEGCHP-THGRCDR-PGD--CDCRPGWR-GELCS 241
Y+C D P QG C + C+ P GRC+ PG C C PG+R G +
Sbjct: 531 YTCACDSGFRLSP--QGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAA 588
Query: 242 QCQPY-------PGCKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEP--CQ 286
+C P C G C + S+ C C + G C QD++ C T P C
Sbjct: 589 ECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC-TQSPGLCG 646
Query: 287 HGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQPCAHGTCSLAGTTRGFTCTC-- 342
GG C+N P + C C GF G CE + CA P PC G C T F C C
Sbjct: 647 RGG-CKNL-PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD--NTAGSFHCACPA 702
Query: 343 ---DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW---TGPACAEDVDEC 396
RG G + PC +G C + F C C G+ T + EDVDEC
Sbjct: 703 GFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDEC 761
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSC-ACLAG-WTGRDCETNVDDCTG---QCLHGAT 451
G C N+ G + C C +G R T+VD+C+ C
Sbjct: 762 ENHLACPG--------QECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGH 813
Query: 452 CIDLVDDFHCACAAGY---AGR--TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF 505
C + F C+CA GY +GR C+ DV++C C GEC++ ++ C C G+
Sbjct: 814 CTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAPGY 872
Query: 506 ----SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSV 561
G +C D D C+ C + C C PG RA D +C +
Sbjct: 873 RPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPG-------HRAGPDLASC-L 923
Query: 562 LVEESERCAEGMCANGGTCVREEGSWR 588
V+E +C + C GS+R
Sbjct: 924 DVDECRERGPALCGS-QRCENSPGSYR 949
Score = 124 bits (300), Expect = 1e-27
Identities = 109/386 (28%), Positives = 143/386 (37%), Gaps = 58/386 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDG 375
PQ C G C G+TC CD G+ G PC G C +
Sbjct: 516 PQVCGPGRC--ISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 572
Query: 376 FTCECADGW-TGPACAE--DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT- 431
F C C G+ GP AE DVDEC + P + C NT G + C C AG+
Sbjct: 573 FRCVCGPGFRAGPRAAECLDVDECH-------RVPPPCDLGRCENTPGSFLCVCPAGYQA 625
Query: 432 ---GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRP 483
G C+ +VD+CT G C G C +L F C C AG+ G C DVD+CA P P
Sbjct: 626 APHGASCQ-DVDECTQSPGLCGRGG-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 683
Query: 484 CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS--PCGNGAACYTAQSDYYC 537
C G C + ++ C CP GF G C+ D D CA S PC G C + + C
Sbjct: 684 C-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQC 740
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXX 597
C G+ T E+ + C + G CV GS++
Sbjct: 741 VCPMGF-----------QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHH 789
Query: 598 XXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR------EGRTGALCELSLDLC 651
G C + + C C GR G +++ L
Sbjct: 790 LHRGRCTDVDECSSGAPPCGPHGHC--TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLE 847
Query: 652 GSSPCRNGGRCVGGSGWWMCECVAGW 677
G C G C+ G + C C G+
Sbjct: 848 GDF-CFPHGECLNTDGSFACTCAPGY 872
Score = 117 bits (281), Expect = 2e-25
Identities = 139/444 (31%), Positives = 180/444 (40%), Gaps = 81/444 (18%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTH-GRCDRPGD---CDCRPGWR----GELCS---QC- 243
C G++G CE+ V C + P GRCD C C G+R G C +C
Sbjct: 661 CPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 720
Query: 244 QPYPGCKHGYCNGS--SWDCTC----DTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPD 297
+ P C +G C + S+ C C N G C+ D++ C H C G C N+ P
Sbjct: 721 RSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACP-GQECVNS-PG 777
Query: 298 QYFCR-CAEG--FSGVDCERVDN-PCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXX 352
+ CR C G C VD PC HG C+ T F C+C G+
Sbjct: 778 SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGYRAPSGR 835
Query: 353 XXXXXXASGPCLHGASCRDH-----LDG-FTCECADGWT-GPACAE--DVDECSGRSMTE 403
+ CL G C H DG F C CA G+ GP A DVDECS + +
Sbjct: 836 PGPCADVN-ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 894
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGW-TGRDCET--NVDDCT--GQCLHGAT-CIDLVD 457
+ C NT G + C C G G D + +VD+C G L G+ C +
Sbjct: 895 SGI--------CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 946
Query: 458 DFHCA--CAAGY-AGR--TCSLDVDDC---APRPCTNGGECVDLLNAYRCI--CPVGFS- 506
+ C C GY AG TC DVD+C P C C + +YRC C G+
Sbjct: 947 SYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQP 1004
Query: 507 --GTNCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLV 563
G C+D D C S CG A C + C C G+ G ARD + C V V
Sbjct: 1005 TPGGGCQDV-DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG-------ARDGRHC-VDV 1055
Query: 564 EESERCAEGMCANGGTCVREEGSW 587
E E +G+C C EGS+
Sbjct: 1056 NECE-TLQGVC-GAALCENVEGSF 1077
Score = 65.3 bits (152), Expect = 1e-09
Identities = 83/301 (27%), Positives = 112/301 (37%), Gaps = 46/301 (15%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHGRC---DRPGDCDCRPGWR---- 236
G + C+ G G + C EG C P HG C D C C PG+R
Sbjct: 819 GSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPR 877
Query: 237 GELC---SQCQPYPGCKHGYCNGS--SWDCTCDTNW--GGILCD-QDLNYCGTHEPCQHG 288
G C +C C+ G C + S++C C G L D++ C P G
Sbjct: 878 GASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCG 937
Query: 289 GT-CENTAPDQYFC--RCAEGF-SGVD--CERVDN--PCAPQPCAHGTCSLAGTTRGFTC 340
CEN+ P Y C C G+ +G + C+ VD P+ C C T + C
Sbjct: 938 SQRCENS-PGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCE--NTPGSYRC 994
Query: 341 T--CDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
T CD G+ GG S H A C++ F C C G+ G A D
Sbjct: 995 TPACDPGYQPTPGGGCQDVDECRNRSFCGAH-AVCQNLPGSFQCLCDQGYEG---ARDGR 1050
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
C + E G C AA C N G + C C + D TG+C+ T +
Sbjct: 1051 HCVDVNECETLQGVC-GAALCENVEGSFLCVC------PNSPEEFDPMTGRCVPPRTSVG 1103
Query: 455 L 455
+
Sbjct: 1104 M 1104
Score = 50.4 bits (115), Expect = 3e-05
Identities = 82/351 (23%), Positives = 118/351 (33%), Gaps = 45/351 (12%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHG--RCDR-PGD--CD--CRPGWRGE 238
G Y C D D G +G + C+E G RC+ PG C C PG++
Sbjct: 946 GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 1005
Query: 239 LCSQCQPYPGCK-------HGYCNG--SSWDCTCDTNWGGILCDQ---DLNYCGTHEPCQ 286
CQ C+ H C S+ C CD + G + D+N C T +
Sbjct: 1006 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC 1065
Query: 287 HGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
CEN + C C S + + + C P + G + +
Sbjct: 1066 GAALCENVE-GSFLCVCPN--SPEEFDPMTGRCVPPRTSVGMSPGSQPQAPVSPVLPARP 1122
Query: 347 GGXXXXXXXXXXASGPCLHGASCRD-HLDGFTCECADGWTGPACAEDV--DECSGRSMTE 403
GP G+ CR+ + D + D A +V EC ++ E
Sbjct: 1123 PPPPLSRRPRKPRKGPV--GSGCRECYFDTAAPDACDN----ILARNVTWQECCC-TVGE 1175
Query: 404 GALGPCVNAAACNNTAGGYSCAC------LAGWTGRDCETNVDDCT---GQCLHGATCID 454
G C Y C LA +VD+C Q C++
Sbjct: 1176 GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVN 1235
Query: 455 LVDDFHCACAAGYAGRTCSL---DVDDCAPR-PCTNGGECVDLLNAYRCIC 501
+ C C+ GY T L D D+CA P GG CV+ + +Y C C
Sbjct: 1236 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 9/61 (14%)
Query: 374 DGFTCECADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
+GFTC C DG+ T AC D++EC E A CVNA C NT G + C C G
Sbjct: 1516 EGFTCRCFDGYRLDMTRMACV-DINECDE---AEAASPLCVNAR-CLNTDGSFRCICRPG 1570
Query: 430 W 430
+
Sbjct: 1571 F 1571
Score = 42.7 bits (96), Expect = 0.006
Identities = 90/364 (24%), Positives = 118/364 (32%), Gaps = 63/364 (17%)
Query: 212 CKEGCHP-THGRCDRPGDCDCRPGWRGELCS--QCQPYPGCKHGYCNGSSWDCTCDTNWG 268
C G H G CD +C + E+C +C+ PG C + T G
Sbjct: 954 CDPGYHAGPEGTCDDVDECQ---EYGPEICGAQRCENTPGSYR--CTPACDPGYQPTPGG 1008
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV----------DCERVDNP 318
G C QD++ C C C+N P + C C +G+ G +CE +
Sbjct: 1009 G--C-QDVDECRNRSFCGAHAVCQNL-PGSFQCLCDQGYEGARDGRHCVDVNECETLQGV 1064
Query: 319 CAPQPCAH--GT--CSLAGTTRGFT-----CTCDRGWGGXXXXXXXXXXASGPCLHGASC 369
C C + G+ C + F C R G S P L
Sbjct: 1065 CGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSVGMSPGSQPQAPVS-PVLPARPP 1123
Query: 370 RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
L + G G C E C + A C N A N T C G
Sbjct: 1124 PPPLSRRPRKPRKGPVGSGCRE----CYFDTAAPDA---CDNILARNVTWQECCCTVGEG 1176
Query: 430 WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL----DVDDCA---PR 482
W G C + C G A L C GY + L DVD+C +
Sbjct: 1177 W-GSGCR--IQQCPGT--ETAEYQSL-----CPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1226
Query: 483 PCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYC 537
C +G CV+ Y C C G+ C D+ D CA P G C Y+C
Sbjct: 1227 VCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHC 1284
Query: 538 HCAP 541
C P
Sbjct: 1285 TCEP 1288
Score = 39.1 bits (87), Expect = 0.077
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 452 CIDLVDDFHCACAAGYA---GRTCSLDVDDC----APRPCTNGGECVDLLNAYRCICPVG 504
C+ + + F C C GY R +D+++C A P C++ ++RCIC G
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Query: 505 FSGTNCEDDRDHCA 518
F+ T+ HCA
Sbjct: 1571 FAPTH---QPHHCA 1581
Score = 37.1 bits (82), Expect = 0.31
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C G+ +C DVD+CA GEC + Y C+CP GF
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 350
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 303 CAEGFSGVD--CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW 346
C GF V+ CE VD C HG C A T G+TC C G+
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGEC--ANTRGGYTCVCPDGF 350
Score = 34.3 bits (75), Expect = 2.2
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 620 GTCLPSALPPGWACGCREG---RTGALCELSLDLCGSS-PCRNGGRCVGGSGWWMCEC 673
G C+ +A PG++C C G T L + D C P GGRCV G + C C
Sbjct: 1231 GVCVNTA--PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 33.1 bits (72), Expect = 5.1
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 628 PPGWACGCREGRT----GALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTGET 681
P + C C G GA C+ +D C SP C GG C G + C C AG+ G
Sbjct: 612 PGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGG-CKNLPGSFRCVCPAGFRGSA 669
Query: 682 C 682
C
Sbjct: 670 C 670
Score = 32.7 bits (71), Expect = 6.7
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 3/45 (6%)
Query: 501 CPVGFSGTN--CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
CP GF N CED + G C +G C + Y C C G+
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGE-CANTRGGYTCVCPDGF 350
Score = 32.7 bits (71), Expect = 6.7
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 19/95 (20%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C G C + G++C C++G+ T D DEC+ P C NT
Sbjct: 1228 CKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE-------PACEGGRCVNTV 1279
Query: 420 GGYSCAC----LAGWTGRDCETN----VDDCTGQC 446
G Y C C + + R C +N +DD G C
Sbjct: 1280 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVC 1314
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 126 bits (303), Expect = 5e-28
Identities = 103/330 (31%), Positives = 140/330 (42%), Gaps = 56/330 (16%)
Query: 220 HGRC-DRPGD--CDCRPGWRGE----LC---SQCQPYP-GCKHGYC--NGSSWDCTCDTN 266
HG C P D C C PG+R C ++C+ P G G C G S++C C+
Sbjct: 74 HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRG 133
Query: 267 W------GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS-----GVDCERV 315
+ GG C DLN C C GG C N P Y C C G+ CE +
Sbjct: 134 YRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINF-PGHYKCNCYPGYRLKASRPPVCEDI 191
Query: 316 DNPCAPQPCAHGTC-SLAGTTRGFTCTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
D P C G C + G+ + C R GG PC G C +
Sbjct: 192 DECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW-CENLP 250
Query: 374 DGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
F C CA G+ G +C DVDEC + + + C+NT G + C CL+G
Sbjct: 251 GSFRCTCAQGYAPAPDGRSCL-DVDECEAGDVCDNGI--------CSNTPGSFQCQCLSG 301
Query: 430 W-TGRD---CETNVDDCT--GQCLHGATCIDLVDDFHCACAAGY---AGRTCSLDVDDCA 480
+ RD CE ++D+C C+ G CI+ + C C G+ GR C D+D+C+
Sbjct: 302 YHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECS 358
Query: 481 PRP--CTNGGECVDLLNAYRCICPVGFSGT 508
P C G C +L +Y C+C GF+ T
Sbjct: 359 QDPSLCLPHGACKNLQGSYVCVCDEGFTPT 388
Score = 108 bits (259), Expect = 1e-22
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 51/331 (15%)
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHG-GTCENTAPDQYFCR 302
C HG C D +C N G Q D+N C EPC G G C NT Y C
Sbjct: 72 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA-EPCGPGRGICMNTG-GSYNCH 129
Query: 303 CAEGF------SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW---GGXXXXX 353
C G+ G C ++ P C G + + C C G+
Sbjct: 130 CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGYRLKASRPPVC 188
Query: 354 XXXXXASGP--CLHGASCRDHLDGFTC-ECADGWT---GPACAEDVDECSGRSMTEGALG 407
P C G C + F C C G+ G AC DV+EC+ EG+
Sbjct: 189 EDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGAC-RDVNECA-----EGS-- 239
Query: 408 PCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDC-TGQCLHGATCIDLVDDFHCA 462
PC + C N G + C C G+ GR C +VD+C G C + F C
Sbjct: 240 PC-SPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQCQ 297
Query: 463 CAAGY---AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVG---FSGTNCEDDRD 515
C +GY R+ D+D+C P C GG+C++ +YRC+CP G G C+ D D
Sbjct: 298 CLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DID 355
Query: 516 HCAGSP--CGNGAACYTAQSDYYCHCAPGWT 544
C+ P C AC Q Y C C G+T
Sbjct: 356 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 386
Score = 94.7 bits (225), Expect = 1e-18
Identities = 115/436 (26%), Positives = 165/436 (37%), Gaps = 60/436 (13%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKE--GCH-PTH---GRCD-RPGD--C-DCRPGW 235
GHY C +C PG++ PVC++ C P+ G+C+ +PG C C+PG+
Sbjct: 168 GHYKC------NCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 221
Query: 236 R---GELC---SQCQPYPGCKHGYCNG--SSWDCTCDTNWG----GILCDQDLNYCGTHE 283
R G C ++C C G+C S+ CTC + G C D++ C +
Sbjct: 222 RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGD 280
Query: 284 PCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFT 339
C +G C NT P + C+C G+ CE +D P C G C T +
Sbjct: 281 VCDNG-ICSNT-PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC--INTNGSYR 336
Query: 340 CTCDRGWG--GXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECADGWTGPAC---AED 392
C C +G G + P CL +C++ + C C +G+T E+
Sbjct: 337 CLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEE 396
Query: 393 VDECSGRS---MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHG 449
V++ + + C + A N T C+ AGW G CE
Sbjct: 397 VEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEIYPCPVYSSAEFH 455
Query: 450 ATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGF-- 505
+ C D Y G D+D+C G+CV+ Y C C GF
Sbjct: 456 SLCPDGKGYTQDNNIVNY-GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYY 514
Query: 506 SGTNCE-DDRDHCAG-SPCGNGAACYTAQSDYYCHCAP----GWTGKNCTQRAARDRKTC 559
G E D D C S C NG C + Y C C P + C +R
Sbjct: 515 DGNLLECVDVDECLDESNCRNG-VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE 573
Query: 560 SVLVEESERCAEGMCA 575
V S+R +GMCA
Sbjct: 574 RRDVCWSQRGEDGMCA 589
Score = 86.6 bits (205), Expect = 4e-16
Identities = 90/343 (26%), Positives = 130/343 (37%), Gaps = 55/343 (16%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C ++C C G+ C DV+EC GP C NT
Sbjct: 72 CGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCV-DVNECEAEPC-----GP--GRGICMNT 122
Query: 419 AGGYSCACLAGWT------GRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGY--- 467
G Y+C C G+ GR C ++++C C G CI+ + C C GY
Sbjct: 123 GGSYNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 181
Query: 468 AGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGF---SGTNCEDDRDHCAGS 520
A R C D+D+C P C +G +C + +++CI C G+ G C D + GS
Sbjct: 182 ASRPPVCE-DIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 239
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC G C + C CA G+ A D ++C + + C G + G C
Sbjct: 240 PCSPGW-CENLPGSFRCTCAQGYA-------PAPDGRSCL----DVDECEAGDVCDNGIC 287
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
GS++ D GG C+ + + C C +G
Sbjct: 288 SNTPGSFQCQCLSGYHLSR-DRSHCEDIDECDFPAACIGGDCINTN--GSYRCLCPQGHR 344
Query: 641 ---GALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
G C+ +D C P C G C G ++C C G+T
Sbjct: 345 LVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 386
Score = 81.8 bits (193), Expect = 1e-14
Identities = 80/291 (27%), Positives = 118/291 (40%), Gaps = 52/291 (17%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX---ASGPCLHGAS-CRDHLDGFTCE 379
C HG C + G ++C C+ G+ + PC G C + + C
Sbjct: 72 CGHGEC-VPGPP-DYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCH 129
Query: 380 CADGWT------GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
C G+ G +C D++EC+ + C + C N G Y C C G+ +
Sbjct: 130 CNRGYRLHVGAGGRSCV-DLNECAKPHL-------CGDGGFCINFPGHYKCNCYPGYRLK 181
Query: 434 D-----CETNVDDCT--GQCLHGATCIDLVDDFHC-ACAAGY---AGRTCSLDVDDCAP- 481
CE ++D+C C G C + F C AC GY G C DV++CA
Sbjct: 182 ASRPPVCE-DIDECRDPSSCPDGK-CENKPGSFKCIACQPGYRSQGGGACR-DVNECAEG 238
Query: 482 RPCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
PC+ G C +L ++RC C G++ G +C D + AG C NG C + C
Sbjct: 239 SPCSPGW-CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGI-CSNTPGSFQC 296
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
C G+ +RDR C E+ + C GG C+ GS+R
Sbjct: 297 QCLSGY-------HLSRDRSHC----EDIDECDFPAACIGGDCINTNGSYR 336
Score = 74.5 bits (175), Expect = 2e-12
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 34/259 (13%)
Query: 437 TNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDVDDCAPRPCTNG-G 488
T D+C C HG C+ D+ C C GY R C +DV++C PC G G
Sbjct: 60 TETDECRLNQNICGHGE-CVPGPPDYSCHCNPGYRSHPQHRYC-VDVNECEAEPCGPGRG 117
Query: 489 ECVDLLNAYRCICP------VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C++ +Y C C VG G +C D + CG+G C Y C+C PG
Sbjct: 118 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 177
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+ K D C + C +G C N + GS++
Sbjct: 178 YRLKASRPPVCEDIDEC----RDPSSCPDGKCEN------KPGSFKCIACQPGYRSQGGG 227
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT----GALCELSLDLCGSSPCRN 658
+ G C LP + C C +G G C L +D C + +
Sbjct: 228 ACRDVNECAEGSPC-SPGWC--ENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCD 283
Query: 659 GGRCVGGSGWWMCECVAGW 677
G C G + C+C++G+
Sbjct: 284 NGICSNTPGSFQCQCLSGY 302
Score = 52.0 bits (119), Expect = 1e-05
Identities = 76/308 (24%), Positives = 111/308 (36%), Gaps = 39/308 (12%)
Query: 229 CDCRPGWRGELCS--QCQPYPGCK-HGYC-NGSSWDCTCDTNWGGILCDQDLNYCGTH-- 282
C GW G+ C C Y + H C +G + + GI +D++ C
Sbjct: 431 CSLGAGW-GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGS 489
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGF 338
E C+ G C NT P Y C C +GF + ++C VD C +G C T G+
Sbjct: 490 EICKEG-KCVNTQPG-YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE--NTRGGY 545
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDGFTCECADGWTGPACAEDVDE 395
C C + RD G CA GPA D D
Sbjct: 546 RCACTPP--AEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFD-DC 602
Query: 396 CSGRSMTEGA-LGPCVNAAACNNTAGGYS--------CACLAGWTGRDCETNVDDCTG-Q 445
C + GA PC A ++ S L G RD +++ +D +
Sbjct: 603 CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR 662
Query: 446 CLHGATCIDLVDDFHCACAAGY---AGRTCSLDVDDCAPRP----CTNGGECVDLLNAYR 498
C+ G C+ C C G+ A R +D+D+C CV+ ++R
Sbjct: 663 CVSGR-CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFR 721
Query: 499 CICPVGFS 506
C+C GF+
Sbjct: 722 CVCKAGFA 729
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 126 bits (303), Expect = 5e-28
Identities = 103/330 (31%), Positives = 140/330 (42%), Gaps = 56/330 (16%)
Query: 220 HGRC-DRPGD--CDCRPGWRGE----LC---SQCQPYP-GCKHGYC--NGSSWDCTCDTN 266
HG C P D C C PG+R C ++C+ P G G C G S++C C+
Sbjct: 587 HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRG 646
Query: 267 W------GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS-----GVDCERV 315
+ GG C DLN C C GG C N P Y C C G+ CE +
Sbjct: 647 YRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINF-PGHYKCNCYPGYRLKASRPPVCEDI 704
Query: 316 DNPCAPQPCAHGTC-SLAGTTRGFTCTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
D P C G C + G+ + C R GG PC G C +
Sbjct: 705 DECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW-CENLP 763
Query: 374 DGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
F C CA G+ G +C DVDEC + + + C+NT G + C CL+G
Sbjct: 764 GSFRCTCAQGYAPAPDGRSCL-DVDECEAGDVCDNGI--------CSNTPGSFQCQCLSG 814
Query: 430 W-TGRD---CETNVDDCT--GQCLHGATCIDLVDDFHCACAAGY---AGRTCSLDVDDCA 480
+ RD CE ++D+C C+ G CI+ + C C G+ GR C D+D+C+
Sbjct: 815 YHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECS 871
Query: 481 PRP--CTNGGECVDLLNAYRCICPVGFSGT 508
P C G C +L +Y C+C GF+ T
Sbjct: 872 QDPSLCLPHGACKNLQGSYVCVCDEGFTPT 901
Score = 108 bits (259), Expect = 1e-22
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 51/331 (15%)
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHG-GTCENTAPDQYFCR 302
C HG C D +C N G Q D+N C EPC G G C NT Y C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA-EPCGPGRGICMNTG-GSYNCH 642
Query: 303 CAEGF------SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW---GGXXXXX 353
C G+ G C ++ P C G + + C C G+
Sbjct: 643 CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGYRLKASRPPVC 701
Query: 354 XXXXXASGP--CLHGASCRDHLDGFTC-ECADGWT---GPACAEDVDECSGRSMTEGALG 407
P C G C + F C C G+ G AC DV+EC+ EG+
Sbjct: 702 EDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGAC-RDVNECA-----EGS-- 752
Query: 408 PCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDC-TGQCLHGATCIDLVDDFHCA 462
PC + C N G + C C G+ GR C +VD+C G C + F C
Sbjct: 753 PC-SPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQCQ 810
Query: 463 CAAGY---AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVG---FSGTNCEDDRD 515
C +GY R+ D+D+C P C GG+C++ +YRC+CP G G C+ D D
Sbjct: 811 CLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DID 868
Query: 516 HCAGSP--CGNGAACYTAQSDYYCHCAPGWT 544
C+ P C AC Q Y C C G+T
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Score = 94.7 bits (225), Expect = 1e-18
Identities = 115/436 (26%), Positives = 165/436 (37%), Gaps = 60/436 (13%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKE--GCH-PTH---GRCD-RPGD--C-DCRPGW 235
GHY C +C PG++ PVC++ C P+ G+C+ +PG C C+PG+
Sbjct: 681 GHYKC------NCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 734
Query: 236 R---GELC---SQCQPYPGCKHGYCNG--SSWDCTCDTNWG----GILCDQDLNYCGTHE 283
R G C ++C C G+C S+ CTC + G C D++ C +
Sbjct: 735 RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGD 793
Query: 284 PCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFT 339
C +G C NT P + C+C G+ CE +D P C G C T +
Sbjct: 794 VCDNG-ICSNT-PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC--INTNGSYR 849
Query: 340 CTCDRGWG--GXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECADGWTGPAC---AED 392
C C +G G + P CL +C++ + C C +G+T E+
Sbjct: 850 CLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEE 909
Query: 393 VDECSGRS---MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHG 449
V++ + + C + A N T C+ AGW G CE
Sbjct: 910 VEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEIYPCPVYSSAEFH 968
Query: 450 ATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGF-- 505
+ C D Y G D+D+C G+CV+ Y C C GF
Sbjct: 969 SLCPDGKGYTQDNNIVNY-GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYY 1027
Query: 506 SGTNCE-DDRDHCAG-SPCGNGAACYTAQSDYYCHCAP----GWTGKNCTQRAARDRKTC 559
G E D D C S C NG C + Y C C P + C +R
Sbjct: 1028 DGNLLECVDVDECLDESNCRNG-VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPE 1086
Query: 560 SVLVEESERCAEGMCA 575
V S+R +GMCA
Sbjct: 1087 RRDVCWSQRGEDGMCA 1102
Score = 86.6 bits (205), Expect = 4e-16
Identities = 90/343 (26%), Positives = 130/343 (37%), Gaps = 55/343 (16%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C ++C C G+ C DV+EC GP C NT
Sbjct: 585 CGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCV-DVNECEAEPC-----GP--GRGICMNT 635
Query: 419 AGGYSCACLAGWT------GRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGY--- 467
G Y+C C G+ GR C ++++C C G CI+ + C C GY
Sbjct: 636 GGSYNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 694
Query: 468 AGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGF---SGTNCEDDRDHCAGS 520
A R C D+D+C P C +G +C + +++CI C G+ G C D + GS
Sbjct: 695 ASRPPVCE-DIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 752
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC G C + C CA G+ A D ++C + + C G + G C
Sbjct: 753 PCSPGW-CENLPGSFRCTCAQGYA-------PAPDGRSCL----DVDECEAGDVCDNGIC 800
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
GS++ D GG C+ + + C C +G
Sbjct: 801 SNTPGSFQCQCLSGYHLSR-DRSHCEDIDECDFPAACIGGDCINTN--GSYRCLCPQGHR 857
Query: 641 ---GALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
G C+ +D C P C G C G ++C C G+T
Sbjct: 858 LVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Score = 81.8 bits (193), Expect = 1e-14
Identities = 80/291 (27%), Positives = 118/291 (40%), Gaps = 52/291 (17%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX---ASGPCLHGAS-CRDHLDGFTCE 379
C HG C + G ++C C+ G+ + PC G C + + C
Sbjct: 585 CGHGEC-VPGPP-DYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCH 642
Query: 380 CADGWT------GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
C G+ G +C D++EC+ + C + C N G Y C C G+ +
Sbjct: 643 CNRGYRLHVGAGGRSCV-DLNECAKPHL-------CGDGGFCINFPGHYKCNCYPGYRLK 694
Query: 434 D-----CETNVDDCT--GQCLHGATCIDLVDDFHC-ACAAGY---AGRTCSLDVDDCAP- 481
CE ++D+C C G C + F C AC GY G C DV++CA
Sbjct: 695 ASRPPVCE-DIDECRDPSSCPDGK-CENKPGSFKCIACQPGYRSQGGGACR-DVNECAEG 751
Query: 482 RPCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYC 537
PC+ G C +L ++RC C G++ G +C D + AG C NG C + C
Sbjct: 752 SPCSPGW-CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGI-CSNTPGSFQC 809
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
C G+ +RDR C E+ + C GG C+ GS+R
Sbjct: 810 QCLSGY-------HLSRDRSHC----EDIDECDFPAACIGGDCINTNGSYR 849
Score = 74.5 bits (175), Expect = 2e-12
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 34/259 (13%)
Query: 437 TNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDVDDCAPRPCTNG-G 488
T D+C C HG C+ D+ C C GY R C +DV++C PC G G
Sbjct: 573 TETDECRLNQNICGHGE-CVPGPPDYSCHCNPGYRSHPQHRYC-VDVNECEAEPCGPGRG 630
Query: 489 ECVDLLNAYRCICP------VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C++ +Y C C VG G +C D + CG+G C Y C+C PG
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+ K D C + C +G C N + GS++
Sbjct: 691 YRLKASRPPVCEDIDEC----RDPSSCPDGKCEN------KPGSFKCIACQPGYRSQGGG 740
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT----GALCELSLDLCGSSPCRN 658
+ G C LP + C C +G G C L +D C + +
Sbjct: 741 ACRDVNECAEGSPC-SPGWC--ENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCD 796
Query: 659 GGRCVGGSGWWMCECVAGW 677
G C G + C+C++G+
Sbjct: 797 NGICSNTPGSFQCQCLSGY 815
Score = 52.0 bits (119), Expect = 1e-05
Identities = 76/308 (24%), Positives = 111/308 (36%), Gaps = 39/308 (12%)
Query: 229 CDCRPGWRGELCS--QCQPYPGCK-HGYC-NGSSWDCTCDTNWGGILCDQDLNYCGTH-- 282
C GW G+ C C Y + H C +G + + GI +D++ C
Sbjct: 944 CSLGAGW-GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGS 1002
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGF 338
E C+ G C NT P Y C C +GF + ++C VD C +G C T G+
Sbjct: 1003 EICKEG-KCVNTQPG-YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE--NTRGGY 1058
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD---HLDGFTCECADGWTGPACAEDVDE 395
C C + RD G CA GPA D D
Sbjct: 1059 RCACTPP--AEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFD-DC 1115
Query: 396 CSGRSMTEGA-LGPCVNAAACNNTAGGYS--------CACLAGWTGRDCETNVDDCTG-Q 445
C + GA PC A ++ S L G RD +++ +D +
Sbjct: 1116 CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR 1175
Query: 446 CLHGATCIDLVDDFHCACAAGY---AGRTCSLDVDDCAPRP----CTNGGECVDLLNAYR 498
C+ G C+ C C G+ A R +D+D+C CV+ ++R
Sbjct: 1176 CVSGR-CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFR 1234
Query: 499 CICPVGFS 506
C+C GF+
Sbjct: 1235 CVCKAGFA 1242
Score = 38.3 bits (85), Expect = 0.13
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 15/125 (12%)
Query: 463 CAAGYA--GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C GY T D+++CA G+C++ +YRC+CP G S R C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHS---LGPSRTQCIAD 397
Query: 521 PCGNGAACYTAQS-DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
+ C+ S ++ C T R R CSV RC C GT
Sbjct: 398 KPEEKSLCFRLVSPEHQCQ-------HPLTTRLTRQLCCCSVGKAWGARCQR--CPTDGT 448
Query: 580 CVREE 584
+E
Sbjct: 449 AAFKE 453
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
P PC NGG+C + +C+CP F+G C+ G G+G
Sbjct: 114 PLPCMNGGQCS---SRNQCLCPPDFTGRFCQVPAGGAGGGTGGSG 155
>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 125 bits (302), Expect = 7e-28
Identities = 159/595 (26%), Positives = 205/595 (34%), Gaps = 107/595 (17%)
Query: 165 CQPNYYNTTCTTFCR----PRDDKFGHYSCT-----PDGDKHCLPGWQGDNCEKP-VCKE 214
C P YY C C+ P D + G C P D C G G C C+
Sbjct: 178 CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQN 237
Query: 215 GCHPTHGRCDRP-GDCDCRPGWRGELCSQCQPY----PGCKH-------GYCNGSSWDCT 262
G G P G C C PGW G +CS P P C G C+ + C
Sbjct: 238 G-----GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCR 292
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDC-ERV--D 316
C + G C ++ + C C A P C C GF+G C +R+ D
Sbjct: 293 CAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPD 352
Query: 317 NPCAPQPCAHGTC----SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLH 365
A TC SL+ C+C GW G GP CLH
Sbjct: 353 GFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLH 412
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C+ C+CA G+TGP CA + + A C NA AC+ G C
Sbjct: 413 GGVCQ--ATSGLCQCAPGYTGPHCA-SLCPPDTYGVNCSARCSCENAIACSPIDG--ECV 467
Query: 426 CLAGWTGRDCETNVD------DCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV- 476
C GW +C C QC H A C C C G+ G C L
Sbjct: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCP 525
Query: 477 -----DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD------HCAGS-PCG 523
+ CA R C + C D ++ RC C G+ G C +C+ + C
Sbjct: 526 KGQFGEGCASRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NG C + C CAPG+ G +C QR+ + + +RC CAN C
Sbjct: 584 NGGTCLPENGN--CVCAPGFRGPSC-QRSCQPGR-------YGKRCVPCKCANHSFCHPS 633
Query: 584 EGS-WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS----ALPPGWA---C-- 633
G+ + GGTC P P GW C
Sbjct: 634 NGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLE 693
Query: 634 GCREGRTGALCELSLDLCGSSPCR--NGGRCVGGSGWWMCECVAGWTGETCAVRV 686
GC G GA C S PC+ G +C +G C C G +G C + +
Sbjct: 694 GCPLGTFGANC--------SQPCQCGPGEKCHPETG--ACVCPPGHSGAPCRIGI 738
Score = 119 bits (286), Expect = 6e-26
Identities = 149/569 (26%), Positives = 195/569 (34%), Gaps = 102/569 (17%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGCH-PTHGRCD-RPGDCDCRPGWR 236
H C C+PGW+GD+C P C + C + CD + G C C G +
Sbjct: 111 HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ 170
Query: 237 GELCSQ-CQP-Y--PGCK-----HGY-CNGSSWDCTCDTNWGGILCDQDLN------YCG 280
C Q C P Y P C+ HG C+ + C C G CD + +C
Sbjct: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDC-----ERVDNPCAPQPCAHGTCSLAGTT 335
+ CQ+GG + Q C C G+ G C E P Q C C G
Sbjct: 231 STHSCQNGGVFQT---PQGSCSCPPGWMGTICSLPCPEGFHGPNCSQEC---RCHNGGLC 284
Query: 336 RGFT--CTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDGF----TCECADGWTGPA 388
FT C C G+ G G C C F C C G+TG
Sbjct: 285 DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDR 344
Query: 389 CAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYSCACLAGWTGRDC-ETNVDDCT 443
C + + C PC ++ +C+ G C+CL GW G C E+ D
Sbjct: 345 CTDRL--CPDGFYGLSCQAPCTCDREHSLSCHPMNG--ECSCLPGWAGLHCNESCPQDTH 400
Query: 444 GQ-------CLHGATCIDLVDDFHCACAAGYAGRTC-SLDVDD-----CAPR-PCTNGGE 489
G CLHG C C CA GY G C SL D C+ R C N
Sbjct: 401 GPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIA 458
Query: 490 CVDLLNAYRCICPVGFSGTNCEDDRD------HC-AGSPCGNGAACYTAQSDYYCHCAPG 542
C + C+C G+ NC C A C + A C + C C PG
Sbjct: 459 CSPIDG--ECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVC--SPQTGACTCTPG 514
Query: 543 WTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
W G +C + + + C+ + ++G G C + G W
Sbjct: 515 WHGAHCQLPCPKGQFGEGCASRCDCDH--SDGCDPVHGRCQCQAG-WMGARCHLSC---- 567
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD------LCGSS 654
+ GGTCLP C C G G C+ S C
Sbjct: 568 -PEGLWGVNCSNTCTCKNGGTCLPE----NGNCVCAPGFRGPSCQRSCQPGRYGKRCVPC 622
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N C +G C C+AGWTG C+
Sbjct: 623 KCANHSFCHPSNG--TCYCLAGWTGPDCS 649
Score = 109 bits (263), Expect = 4e-23
Identities = 144/533 (27%), Positives = 190/533 (35%), Gaps = 89/533 (16%)
Query: 210 PVCKEGCHPTHGRCDRPGDCDCRPGWRGELC-SQCQP---YPGC-KHGYC-NGSSWD--- 260
P+C + C HGRC P C C PGWRG+ C S+C P P C K C N SS D
Sbjct: 103 PLCAQEC--VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 261 --CTCDTNWGGILCDQDL--NYCG--THEPCQ-HGGTCENTAPDQYFCRCAEGFSGVDCE 313
C+C + C Q Y G CQ HG C+ P C C +G C
Sbjct: 161 GVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD---PQTGACFCPAERTGPSC- 216
Query: 314 RVDNPCAPQ------PCAHGTCSLAGT--TRGFTCTCDRGWGGXXXXXXXXXXASGP-CL 364
D C+ P H +C G T +C+C GW G GP C
Sbjct: 217 --DVSCSQGTSGFFCPSTH-SCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS 273
Query: 365 HGASCRDH--LDGFT--CECADGWTGPACAEDV------DECSGR--SMTEGALGPCVNA 412
C + D FT C CA G+TG C E+ +C+ + P A
Sbjct: 274 QECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA 333
Query: 413 AACNNTAGGYSCA---CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG 469
C + G C C G+ G C+ CT H +C + + C+C G+AG
Sbjct: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQA---PCTCDREHSLSCHPM--NGECSCLPGWAG 388
Query: 470 RTCSLDVDDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNC------EDDRDH 516
C+ P C +GG C + C C G++G +C + +
Sbjct: 389 LHCNESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVN 446
Query: 517 C-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA-EGMC 574
C A C N AC + D C C GW NC+ T S +CA E +C
Sbjct: 447 CSARCSCENAIAC--SPIDGECVCKEGWQRGNCSVPCPPG--TWGFSCNASCQCAHEAVC 502
Query: 575 A-NGGTCVREEGSWRXXXXXX--XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
+ G C G W + G C A G
Sbjct: 503 SPQTGACTCTPG-WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 632 AC--GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C EG G C + C+NGG C+ +G C C G+ G +C
Sbjct: 562 RCHLSCPEGLWGVNCS------NTCTCKNGGTCLPENG--NCVCAPGFRGPSC 606
Score = 92.7 bits (220), Expect = 6e-18
Identities = 93/340 (27%), Positives = 123/340 (36%), Gaps = 61/340 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKE 214
LC P+ Y C+ C + +C+P DG+ C GWQ NC P C
Sbjct: 437 LCPPDTYGVNCSARCSCENA----IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNA 492
Query: 215 GCHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC 272
C H P G C C PGW G C P P + G G + C CD + G C
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQL--PCPKGQFG--EGCASRCDCDHSDG---C 545
Query: 273 DQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV-----DNPCAPQPCAHG 327
D C CQ G C EG GV+C C P+ +G
Sbjct: 546 DPVHGRC----QCQAGWMGARC-----HLSCPEGLWGVNCSNTCTCKNGGTCLPE---NG 593
Query: 328 TCSLAGTTRGFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT 385
C A RG +C +C G G C + + C H TC C GWT
Sbjct: 594 NCVCAPGFRGPSCQRSCQPGRYGKRC-------VPCKCANHSFC--HPSNGTCYCLAGWT 644
Query: 386 GPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC------ETN 438
GP C++ G + + C + C+ G SC C GWTG C T
Sbjct: 645 GPDCSQPCPPGHWGENCAQTC--QCHHGGTCHPQDG--SCICPLGWTGHHCLEGCPLGTF 700
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
+C+ C G + C C G++G C + + +
Sbjct: 701 GANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 125 bits (302), Expect = 7e-28
Identities = 159/595 (26%), Positives = 205/595 (34%), Gaps = 107/595 (17%)
Query: 165 CQPNYYNTTCTTFCR----PRDDKFGHYSCT-----PDGDKHCLPGWQGDNCEKP-VCKE 214
C P YY C C+ P D + G C P D C G G C C+
Sbjct: 178 CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQN 237
Query: 215 GCHPTHGRCDRP-GDCDCRPGWRGELCSQCQPY----PGCKH-------GYCNGSSWDCT 262
G G P G C C PGW G +CS P P C G C+ + C
Sbjct: 238 G-----GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCR 292
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTA---PDQYFCRCAEGFSGVDC-ERV--D 316
C + G C ++ + C C A P C C GF+G C +R+ D
Sbjct: 293 CAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPD 352
Query: 317 NPCAPQPCAHGTC----SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP-------CLH 365
A TC SL+ C+C GW G GP CLH
Sbjct: 353 GFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLH 412
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
G C+ C+CA G+TGP CA + + A C NA AC+ G C
Sbjct: 413 GGVCQ--ATSGLCQCAPGYTGPHCA-SLCPPDTYGVNCSARCSCENAIACSPIDG--ECV 467
Query: 426 CLAGWTGRDCETNVD------DCTG--QCLHGATCIDLVDDFHCACAAGYAGRTCSLDV- 476
C GW +C C QC H A C C C G+ G C L
Sbjct: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCP 525
Query: 477 -----DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRD------HCAGS-PCG 523
+ CA R C + C D ++ RC C G+ G C +C+ + C
Sbjct: 526 KGQFGEGCASRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
Query: 524 NGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVRE 583
NG C + C CAPG+ G +C QR+ + + +RC CAN C
Sbjct: 584 NGGTCLPENGN--CVCAPGFRGPSC-QRSCQPGR-------YGKRCVPCKCANHSFCHPS 633
Query: 584 EGS-WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPS----ALPPGWA---C-- 633
G+ + GGTC P P GW C
Sbjct: 634 NGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLE 693
Query: 634 GCREGRTGALCELSLDLCGSSPCR--NGGRCVGGSGWWMCECVAGWTGETCAVRV 686
GC G GA C S PC+ G +C +G C C G +G C + +
Sbjct: 694 GCPLGTFGANC--------SQPCQCGPGEKCHPETG--ACVCPPGHSGAPCRIGI 738
Score = 119 bits (286), Expect = 6e-26
Identities = 149/569 (26%), Positives = 195/569 (34%), Gaps = 102/569 (17%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEK--------PVCKEGCH-PTHGRCD-RPGDCDCRPGWR 236
H C C+PGW+GD+C P C + C + CD + G C C G +
Sbjct: 111 HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ 170
Query: 237 GELCSQ-CQP-Y--PGCK-----HGY-CNGSSWDCTCDTNWGGILCDQDLN------YCG 280
C Q C P Y P C+ HG C+ + C C G CD + +C
Sbjct: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDC-----ERVDNPCAPQPCAHGTCSLAGTT 335
+ CQ+GG + Q C C G+ G C E P Q C C G
Sbjct: 231 STHSCQNGGVFQT---PQGSCSCPPGWMGTICSLPCPEGFHGPNCSQEC---RCHNGGLC 284
Query: 336 RGFT--CTCDRGWGGXXXXXXXXXXASG-PCLHGASCRDHLDGF----TCECADGWTGPA 388
FT C C G+ G G C C F C C G+TG
Sbjct: 285 DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDR 344
Query: 389 CAEDVDECSGRSMTEGALGPCV----NAAACNNTAGGYSCACLAGWTGRDC-ETNVDDCT 443
C + + C PC ++ +C+ G C+CL GW G C E+ D
Sbjct: 345 CTDRL--CPDGFYGLSCQAPCTCDREHSLSCHPMNG--ECSCLPGWAGLHCNESCPQDTH 400
Query: 444 GQ-------CLHGATCIDLVDDFHCACAAGYAGRTC-SLDVDD-----CAPR-PCTNGGE 489
G CLHG C C CA GY G C SL D C+ R C N
Sbjct: 401 GPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIA 458
Query: 490 CVDLLNAYRCICPVGFSGTNCEDDRD------HC-AGSPCGNGAACYTAQSDYYCHCAPG 542
C + C+C G+ NC C A C + A C + C C PG
Sbjct: 459 CSPIDG--ECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVC--SPQTGACTCTPG 514
Query: 543 WTGKNCTQRAARDR--KTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
W G +C + + + C+ + ++G G C + G W
Sbjct: 515 WHGAHCQLPCPKGQFGEGCASRCDCDH--SDGCDPVHGRCQCQAG-WMGARCHLSC---- 567
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLD------LCGSS 654
+ GGTCLP C C G G C+ S C
Sbjct: 568 -PEGLWGVNCSNTCTCKNGGTCLPE----NGNCVCAPGFRGPSCQRSCQPGRYGKRCVPC 622
Query: 655 PCRNGGRCVGGSGWWMCECVAGWTGETCA 683
C N C +G C C+AGWTG C+
Sbjct: 623 KCANHSFCHPSNG--TCYCLAGWTGPDCS 649
Score = 109 bits (263), Expect = 4e-23
Identities = 144/533 (27%), Positives = 190/533 (35%), Gaps = 89/533 (16%)
Query: 210 PVCKEGCHPTHGRCDRPGDCDCRPGWRGELC-SQCQP---YPGC-KHGYC-NGSSWD--- 260
P+C + C HGRC P C C PGWRG+ C S+C P P C K C N SS D
Sbjct: 103 PLCAQEC--VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 261 --CTCDTNWGGILCDQDL--NYCG--THEPCQ-HGGTCENTAPDQYFCRCAEGFSGVDCE 313
C+C + C Q Y G CQ HG C+ P C C +G C
Sbjct: 161 GVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD---PQTGACFCPAERTGPSC- 216
Query: 314 RVDNPCAPQ------PCAHGTCSLAGT--TRGFTCTCDRGWGGXXXXXXXXXXASGP-CL 364
D C+ P H +C G T +C+C GW G GP C
Sbjct: 217 --DVSCSQGTSGFFCPSTH-SCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS 273
Query: 365 HGASCRDH--LDGFT--CECADGWTGPACAEDV------DECSGR--SMTEGALGPCVNA 412
C + D FT C CA G+TG C E+ +C+ + P A
Sbjct: 274 QECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA 333
Query: 413 AACNNTAGGYSCA---CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAG 469
C + G C C G+ G C+ CT H +C + + C+C G+AG
Sbjct: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQA---PCTCDREHSLSCHPM--NGECSCLPGWAG 388
Query: 470 RTCSLDVDDCAPRP-------CTNGGECVDLLNAYRCICPVGFSGTNC------EDDRDH 516
C+ P C +GG C + C C G++G +C + +
Sbjct: 389 LHCNESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVN 446
Query: 517 C-AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA-EGMC 574
C A C N AC + D C C GW NC+ T S +CA E +C
Sbjct: 447 CSARCSCENAIAC--SPIDGECVCKEGWQRGNCSVPCPPG--TWGFSCNASCQCAHEAVC 502
Query: 575 A-NGGTCVREEGSWRXXXXXX--XXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
+ G C G W + G C A G
Sbjct: 503 SPQTGACTCTPG-WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 632 AC--GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C EG G C + C+NGG C+ +G C C G+ G +C
Sbjct: 562 RCHLSCPEGLWGVNCS------NTCTCKNGGTCLPENG--NCVCAPGFRGPSC 606
Score = 92.7 bits (220), Expect = 6e-18
Identities = 93/340 (27%), Positives = 123/340 (36%), Gaps = 61/340 (17%)
Query: 164 LCQPNYYNTTCTTFCRPRDDKFGHYSCTP-DGDKHCLPGWQGDNCEKPV--------CKE 214
LC P+ Y C+ C + +C+P DG+ C GWQ NC P C
Sbjct: 437 LCPPDTYGVNCSARCSCENA----IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNA 492
Query: 215 GCHPTHGRCDRP--GDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC 272
C H P G C C PGW G C P P + G G + C CD + G C
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQL--PCPKGQFG--EGCASRCDCDHSDG---C 545
Query: 273 DQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV-----DNPCAPQPCAHG 327
D C CQ G C EG GV+C C P+ +G
Sbjct: 546 DPVHGRC----QCQAGWMGARC-----HLSCPEGLWGVNCSNTCTCKNGGTCLPE---NG 593
Query: 328 TCSLAGTTRGFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT 385
C A RG +C +C G G C + + C H TC C GWT
Sbjct: 594 NCVCAPGFRGPSCQRSCQPGRYGKRC-------VPCKCANHSFC--HPSNGTCYCLAGWT 644
Query: 386 GPACAEDVDECS-GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC------ETN 438
GP C++ G + + C + C+ G SC C GWTG C T
Sbjct: 645 GPDCSQPCPPGHWGENCAQTC--QCHHGGTCHPQDG--SCICPLGWTGHHCLEGCPLGTF 700
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
+C+ C G + C C G++G C + + +
Sbjct: 701 GANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
>AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein
protein.
Length = 252
Score = 125 bits (301), Expect = 9e-28
Identities = 55/137 (40%), Positives = 72/137 (52%), Gaps = 9/137 (6%)
Query: 376 FTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
+ C C G+ G C E+ +EC PC+NAA C + GY C CLA + G C
Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLS--------APCLNAATCRDLVNGYECVCLAEYKGTHC 55
Query: 436 ETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLL 494
E D C CL+GATC + C CA G+ G C +D+++C PC +GG C+D
Sbjct: 56 ELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQP 115
Query: 495 NAYRCICPVGFSGTNCE 511
N Y C CP G+ G NCE
Sbjct: 116 NGYNCHCPHGWVGANCE 132
Score = 123 bits (297), Expect = 3e-27
Identities = 55/129 (42%), Positives = 69/129 (53%), Gaps = 3/129 (2%)
Query: 422 YSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
Y C C G+ G CE ++C + CL+ ATC DLV+ + C C A Y G C L D CA
Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 63
Query: 481 PRPCTNGGEC-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C NG C D LN CIC GF+G C+ D + C +PC +G +C + Y CHC
Sbjct: 64 NVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 122
Query: 540 APGWTGKNC 548
GW G NC
Sbjct: 123 PHGWVGANC 131
Score = 100 bits (239), Expect = 3e-20
Identities = 47/135 (34%), Positives = 63/135 (46%), Gaps = 5/135 (3%)
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
G+S+ C CD + G+ C+++ N C PC + TC + + Y C C + G CE
Sbjct: 1 GTSYKCLCDPGYHGLYCEEEYNEC-LSAPCLNAATCRDLV-NGYECVCLAEYKGTHCELY 58
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
+PCA C +G TC G TC C G+ G S PC HG SC D +
Sbjct: 59 KDPCANVSCLNGATCDSDGLNG--TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPN 116
Query: 375 GFTCECADGWTGPAC 389
G+ C C GW G C
Sbjct: 117 GYNCHCPHGWVGANC 131
Score = 98.3 bits (234), Expect = 1e-19
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 9/138 (6%)
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
+ C CD G+ G S PCL+ A+CRD ++G+ C C + G C D C+
Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 63
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLV 456
S C+N A C++ +C C G+TG +C+ ++++C + C HG +C+D
Sbjct: 64 NVS--------CLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQP 115
Query: 457 DDFHCACAAGYAGRTCSL 474
+ ++C C G+ G C +
Sbjct: 116 NGYNCHCPHGWVGANCEI 133
Score = 92.3 bits (219), Expect = 8e-18
Identities = 51/155 (32%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
Y C C G+ G+ CE N C PC + TC G+ C C + G
Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCR--DLVNGYECVCLAEYKGTHCELYKDP 61
Query: 358 XASGPCLHGASC-RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACN 416
A+ CL+GA+C D L+G TC CA G+TG C D++EC PC + +C
Sbjct: 62 CANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDS--------NPCHHGGSCL 112
Query: 417 NTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGAT 451
+ GY+C C GW G +CE ++ +G T
Sbjct: 113 DQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLT 147
Score = 59.7 bits (138), Expect = 5e-08
Identities = 40/153 (26%), Positives = 57/153 (37%), Gaps = 20/153 (13%)
Query: 496 AYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARD 555
+Y+C+C G+ G CE++ + C +PC N A C + Y C C + G +C
Sbjct: 3 SYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL----- 57
Query: 556 RKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXX 615
+ CA C NG TC + + D
Sbjct: 58 ---------YKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD----IDINECDSNP 104
Query: 616 XQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
GG+CL P G+ C C G GA CE+ L
Sbjct: 105 CHHGGSCLDQ--PNGYNCHCPHGWVGANCEIHL 135
Score = 57.2 bits (132), Expect = 3e-07
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
G TC L C C G TG C++ ++ C S+PC +GG C+ + C C GW
Sbjct: 70 GATCDSDGL--NGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWV 127
Query: 679 GETCAVRV 686
G C + +
Sbjct: 128 GANCEIHL 135
Score = 56.4 bits (130), Expect = 5e-07
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 198 CLPGWQGDNCEKPV--CKEGCHPTHGRCD---RPGDCDCRPGWRGELCSQCQPYPG-CKH 251
C PG+ G CE+ C C +C C ++G + C+ Y C +
Sbjct: 8 CDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKG---THCELYKDPCAN 64
Query: 252 GYC-NGSSWD-------CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
C NG++ D C C + G CD D+N C ++ PC HGG+C + P+ Y C C
Sbjct: 65 VSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSN-PCHHGGSCLDQ-PNGYNCHC 122
Query: 304 AEGFSGVDCE 313
G+ G +CE
Sbjct: 123 PHGWVGANCE 132
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/58 (34%), Positives = 26/58 (44%)
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G+ C C G CEL D C + C NG C C C G+TGE C + ++
Sbjct: 41 GYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDIN 98
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 13/97 (13%)
Query: 198 CLPGWQGDNCE--KPVCKEGCHPTHGRCDRPG---DCDCRPGWRGELC----SQCQPYPG 248
CL ++G +CE K C CD G C C PG+ GE C ++C P
Sbjct: 46 CLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNP- 104
Query: 249 CKHG-YC--NGSSWDCTCDTNWGGILCDQDLNYCGTH 282
C HG C + ++C C W G C+ L + H
Sbjct: 105 CHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGH 141
Score = 37.9 bits (84), Expect = 0.18
Identities = 17/52 (32%), Positives = 23/52 (44%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C G G CE + C S+PC N C + C C+A + G C
Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 55
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 99 bits (238), Expect = 4e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 99 bits (238), Expect = 4e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 99 bits (238), Expect = 4e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 99.1 bits (236), Expect = 7e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDFCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 106 bits (254), Expect = 4e-22
Identities = 121/474 (25%), Positives = 173/474 (36%), Gaps = 63/474 (13%)
Query: 241 SQCQPYPG-CKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTH--EPC---QHGGTCE 292
++C+ +PG C +G C S+ C C G++ D C EPC C
Sbjct: 871 NECESFPGVCPNGRCVNTAGSFRCECPE---GLMLDASGRLCVDVRLEPCFLRWDEDECG 927
Query: 293 NTAPDQYF---CRCAEGFS-GVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
T P +Y C C+ G GV+CE P P + SL GF
Sbjct: 928 VTLPGKYLMDVCCCSIGAVWGVECE-----ACPDPESLEFASLCPRGLGFASRDFLSGRP 982
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
G C HG +CR+ + F C CA G+ A D E + + E + P
Sbjct: 983 FYKDVNECKVFPGLCTHG-TCRNTVGSFHCACAGGF-----ALDAQERNCTDIDECRISP 1036
Query: 409 -CVNAAACNNTAGGYSCACLAGWTG-----RDCETNVDDCTGQCL--HGATCIDLVDDFH 460
C NT G + C C G+ ++C +VD+C L G TC + +
Sbjct: 1037 DLCGQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYK 1095
Query: 461 CACAAGY---AGRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSGTNCED--- 512
C C G+ A T D+D+C+ C + G+CV+++ A++C C GF T
Sbjct: 1096 CQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCV 1154
Query: 513 DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESER-CAE 571
D + C G C + Y C C G++ RA D C EE+ R C +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYS-LMPDGRACADVDEC----EENPRVCDQ 1209
Query: 572 GMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGW 631
G C N G R G C +
Sbjct: 1210 GHCTN------MPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDC--ENTKGSF 1261
Query: 632 ACGCREG---RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
C C+ G R GA +D C G C + C+ G + C C+ GW G+
Sbjct: 1262 VCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGD 1315
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 97.1 bits (231), Expect = 3e-19
Identities = 135/515 (26%), Positives = 189/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 124 bits (300), Expect = 1e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1142 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1197
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1198 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1253
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1307
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1308 CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1366
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1367 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1423
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1424 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 99 bits (238), Expect = 4e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 87.0 bits (206), Expect = 3e-16
Identities = 104/395 (26%), Positives = 152/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C+C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCQCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1101
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 620 GTCLPSALPPGWACGCREGRTGAL---CELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
G CLP+ P + C C G T + C + +D C SSPC +G CV G + C+C G
Sbjct: 422 GRCLPT--PSSYRCECNVGYTQDVRGEC-IDVDECTSSPCHHGD-CVNIPGTYHCQCYPG 477
Query: 677 W 677
+
Sbjct: 478 F 478
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 124 bits (299), Expect = 2e-27
Identities = 138/468 (29%), Positives = 181/468 (38%), Gaps = 92/468 (19%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQG-----------DNCEKP--VCKE 214
N T CR D G +C TP + C PG++ D C + +C+
Sbjct: 1032 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1091
Query: 215 GCHPTHGRCDRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCD 264
G T D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1092 G---TCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1148
Query: 265 TNWGGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERV 315
G D C C Q+GG C NT Y C C +G+S G C V
Sbjct: 1149 A---GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADV 1204
Query: 316 DNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGAS 368
D C P C G C+ G C C G+ P CLHG
Sbjct: 1205 DE-CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-D 1260
Query: 369 CRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA 425
C + F C C G+ G DVDEC E C + A+C N G +SC
Sbjct: 1261 CENTKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCR 1314
Query: 426 CLAGWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDC 479
CL GW G E ++D+C Q C C+++ + C C G+AG C D D+C
Sbjct: 1315 CLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDEC 1373
Query: 480 APRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQ 532
A C N G+C++ YRC C +GF T C+ D D CA G+ C G +C
Sbjct: 1374 AENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLP 1430
Query: 533 SDYYCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
+ C C G+ G NCT D C+ + C G+C N
Sbjct: 1431 GMFRCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1469
Score = 118 bits (285), Expect = 8e-26
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 992 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1049
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1050 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1107
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1108 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1159
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1160 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1216
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1217 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1273
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1274 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1324
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1325 ECHDLDECISQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1380
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1381 DNG-QCLNAPGGYRCECEMGF 1400
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2055 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2111
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2112 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2170
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2171 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2221
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C N G CV+
Sbjct: 2222 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVN-GRCVNTA 2279
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2280 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2339
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2340 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2394
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2395 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2453
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2454 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2484
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2333 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2383
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2384 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2436
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2437 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2493
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2494 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2546
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2547 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2604
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2605 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2647
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1728 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1786
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1787 CINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1845
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1846 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1895
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1896 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1954
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1955 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2012
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2013 GHRCFDTRQSFCFTRFEAGKCS 2034
Score = 99 bits (238), Expect = 4e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 811 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 868
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 869 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 915
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 916 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 970
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 971 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1021
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1022 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1078
Query: 476 VDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1079 VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1136
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1137 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1185
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1186 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1243
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1244 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1276
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1573 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSGICGPGTCYNT 1631
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1632 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1690
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1691 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1738
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1739 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1797
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1798 CTRGYKLSPGGAC-VGQNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1855
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1856 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1910
Query: 575 AN 576
N
Sbjct: 1911 LN 1912
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1141 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1200
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1201 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1259
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1260 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1315
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1316 LPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1375
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1376 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1427
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1428 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1485
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1486 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1544
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1545 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1594
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2128 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2186
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2187 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2244
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2245 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2301
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2302 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2360
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2361 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2419
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2420 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2478
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2479 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2525
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 426 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 482
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 483 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 534
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 535 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 592
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 593 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 651
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 652 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 710
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 711 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 768
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 769 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 801
Score = 82.2 bits (194), Expect = 8e-15
Identities = 100/382 (26%), Positives = 141/382 (36%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1291 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPG 1350
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1351 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1408
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1409 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1465
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1466 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1524
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1525 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1571
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ CG G CY
Sbjct: 1572 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG-TCYN 1630
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1631 TLGNYTCVCPAEYLQVNGGNNC 1652
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2363 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2422
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2423 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2478
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2479 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2536
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2537 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2588
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2589 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2645
Query: 466 GY 467
GY
Sbjct: 2646 GY 2647
Score = 78.2 bits (184), Expect = 1e-13
Identities = 122/480 (25%), Positives = 168/480 (35%), Gaps = 98/480 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 669 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 727
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 728 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 784
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 785 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 838
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 839 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 878
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 879 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 937
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 938 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 992
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 993 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1051
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P CR GG C G + C+C G
Sbjct: 1052 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPG 1108
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1856 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1911
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1912 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1969
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1970 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2025
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2026 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2077
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2078 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2135
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2136 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2193
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2194 SYLCTCPAGYT 2204
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 91 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 141
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 142 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 187
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 188 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 247
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 248 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 298
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 108 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 161
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 162 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 216
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 217 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 273
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 274 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 329
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 108 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 160
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 161 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 194
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 144 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 197
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 198 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 252
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 253 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 310
Query: 369 CRDHLDG 375
C L G
Sbjct: 311 CAGDLAG 317
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 69 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 120
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 121 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 159
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 160 RG-CHNGGRCIGPN---RCACVYGFMGPQC 185
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 127 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 183
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 184 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 239
Query: 325 AHG 327
G
Sbjct: 240 RRG 242
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 124 bits (298), Expect = 2e-27
Identities = 138/465 (29%), Positives = 181/465 (38%), Gaps = 86/465 (18%)
Query: 171 NTTCTTFCRPRDDKFGHYSC--TPDG-DKHCLPGWQGD-----NC-EKPVC-KEGCHPTH 220
N T CR D G +C TP + C PG++ NC + C ++
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWG 1084
Query: 221 GRC---DRPGDCDCRPGW----RGELCS---QCQPYPG-CKHGYCNG--SSWDCTCDTNW 267
G C D C C PG +G C +C G C HG C ++ C+C
Sbjct: 1085 GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHA-- 1142
Query: 268 GGILCDQDLNYCGTHEPC--QHGGT---CENTAPDQYFCRCAEGFS----GVDCERVDNP 318
G D C C Q+GG C NT Y C C +G+S G C VD
Sbjct: 1143 -GFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSLMPDGRACADVDE- 1199
Query: 319 CAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP--CLHGASCRD 371
C P C G C+ G C C G+ P CLHG C +
Sbjct: 1200 CEENPRVCDQGHCT--NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-DCEN 1256
Query: 372 HLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
F C C G+ G DVDEC E C + A+C N G +SC CL
Sbjct: 1257 TKGSFVCHCQLGYMVRKGATGCSDVDEC------EVGGHNCDSHASCLNIPGSFSCRCLP 1310
Query: 429 GWTGRDCET-NVDDCTGQ---CLHGATCIDLVDDFHCACAAGYAGR--TCSLDVDDCAPR 482
GW G E ++D+C Q C C+++ + C C G+AG C D D+CA
Sbjct: 1311 GWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDECAEN 1369
Query: 483 P--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCA-GSPCGNGAACYTAQSDY 535
C N G+C++ YRC C +GF T C+ D D CA G+ C G +C +
Sbjct: 1370 VDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFG-SCENLPGMF 1426
Query: 536 YCHCAPGWT----GKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C C G+ G NCT D C+ + C G+C N
Sbjct: 1427 RCICNGGYELDRGGGNCT-----DINECA----DPVNCINGVCIN 1462
Score = 118 bits (283), Expect = 1e-25
Identities = 124/441 (28%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 274 QDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDN-PCAPQPCAHG 327
+D+N C C HG TC NT + C CA GF+ +C +D +P C G
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTV-GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCL-HGASCRDHLDGFTCECAD 382
TC T F C C G+ A P L G +C + + C+C
Sbjct: 1043 TC--VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPP 1100
Query: 383 GWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG---RDC 435
G G AC ED+DECS +++G C + C N G + C+C AG+ R
Sbjct: 1101 GHELTAKGTAC-EDIDECS---LSDGL---CPHGQ-CVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 436 ETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTN 486
++++C G C CI+ + C+C GY+ GR C+ DVD+C PR C
Sbjct: 1153 CVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ 1209
Query: 487 GGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCA 540
G C ++ +RC+C GF T C D D C +P C +G C + + CHC
Sbjct: 1210 G-HCTNMPGGHRCLCYDGFMATPDMRTCVDV-DECDLNPHICLHGD-CENTKGSFVCHCQ 1266
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G+ + + CS V+E E C + +C+ GS+
Sbjct: 1267 LGYMVR-------KGATGCSD-VDECEVGGHN-CDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA--LCELSLDLCGSSP--C 656
+ G CL +P + C CR+G G CE D C + C
Sbjct: 1318 ECHDLDECVSQEHRCSPRGD-CLN--VPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLC 1373
Query: 657 RNGGRCVGGSGWWMCECVAGW 677
NG +C+ G + CEC G+
Sbjct: 1374 DNG-QCLNAPGGYRCECEMGF 1393
Score = 105 bits (253), Expect = 6e-22
Identities = 129/451 (28%), Positives = 170/451 (37%), Gaps = 73/451 (16%)
Query: 280 GTHEPCQHGGTCENTAPDQYFCRCAEG-FSGVDCERVD-NPCAPQP--CAHGTCSLAGTT 335
G +PC+ E +A Q C G G D R D N CA P C +G C T
Sbjct: 2048 GWGDPCELCPQ-EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC--VNTD 2104
Query: 336 RGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC-- 389
F C C G+ G PC G +C + + GF C CADG+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMT 2163
Query: 390 AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-G 444
ED+DECS L P + A C+NT G Y C C AG+T R+ C +VD+C G
Sbjct: 2164 CEDIDECS--------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADG 2214
Query: 445 Q--C-LHGATCIDLVDDFHCACAAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
Q C G C +L+ F C C G +G C+ D ++C +P C NG CV+
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTA 2272
Query: 495 NAYRCICPVGFSG----TNCEDDRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGW 543
++RC C GF T C D R + C + ++ A + C C GW
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Query: 544 TGKNC----TQRAARDRKTC---SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXX 591
G C + RK C S E R +CA+ G C+ GS+R
Sbjct: 2333 -GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR--- 2387
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
D+ T L + C C G G C+
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-D 2446
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
LD C S CV G + C C G+T
Sbjct: 2447 LDECTSRQHNCQFLCVNTVGAFTCRCPPGFT 2477
Score = 105 bits (251), Expect = 1e-21
Identities = 101/346 (29%), Positives = 145/346 (41%), Gaps = 62/346 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
C GW G C C P PG S++ C G +D++ C C H
Sbjct: 2326 CGGGRGW-GPRCELC-PLPGT-------SAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCA--PQPCAHGTCSLAGTTRG-FTC 340
G C N+ + C C G++ C +D C+ P+PC L T+G F C
Sbjct: 2377 G-ECINSL-GSFRCHCQAGYTPDATATTCLDMDE-CSQVPKPCTF----LCKNTKGSFLC 2429
Query: 341 TCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDV 393
+C RG+ G C C + + FTC C G+T AC ++
Sbjct: 2430 SCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDN- 2486
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTG--QCL 447
DECS + GPC C+NT G + C C G+T G CE +V++C G +C
Sbjct: 2487 DECSAQP------GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQ 2539
Query: 448 HGATCIDLVDDFHCACAAGYAGRT---CSLDVDDCAPRPCTNG-GECVDLLNAYRCICPV 503
HG C + + + C+C G+ + +D ++CA P T G C + L +RC+CP
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 504 GFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGW 543
GF C+ D D CAG PC +C + C C G+
Sbjct: 2598 GFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 103 bits (246), Expect = 4e-21
Identities = 87/322 (27%), Positives = 125/322 (38%), Gaps = 41/322 (12%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPCAPQPCAHGTCS 330
D++ CG G C N + C C GF+ + CE VD + +
Sbjct: 1721 DIDECGEIPAICANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 331 LAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
+ C C RG+ GG C HG C D + C C G+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQA 1838
Query: 387 PA---CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVD 440
A D+DEC + PC N C N G Y+C C G+ DC + D
Sbjct: 1839 SADQTLCMDIDECDRQ--------PCGNGT-CKNIIGSYNCLCFPGFVVTHNGDC-VDFD 1888
Query: 441 DCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTN-GGECVD 492
+CT GQ C++ FHC C G+ G+ C +D ++C T G C +
Sbjct: 1889 ECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN 1947
Query: 493 LLNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNC 548
L ++RCICP GF +C D D C+ P C G C + + C C PG+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDN 2005
Query: 549 TQRAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCS 2027
Score = 98.7 bits (235), Expect = 9e-20
Identities = 136/515 (26%), Positives = 190/515 (36%), Gaps = 84/515 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKHGYCN 255
CL +G C + + C +C G W G C +C+ P C G+
Sbjct: 804 CLDSTKG-TCWLKIQESRCEVNLQGASLRSECCATLGAAW-GSPCERCEIDPACARGFAR 861
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERV 315
+ G+ CD D+N C + G C NTA + C C EG R+
Sbjct: 862 MT-----------GVTCD-DVNECESFPGVCPNGRCVNTA-GSFRCECPEGLMLDASGRL 908
Query: 316 DNPCAPQPC----AHGTC--SLAGTTRGFTCTCDRG--WGGXXXXXXXXXXASGPCLHGA 367
+PC C +L G R C C G WG L A
Sbjct: 909 CVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG-----VECEACPDPESLEFA 963
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
S GF D +G +DV+EC + G C + C NT G + CAC
Sbjct: 964 SLCPRGLGFASR--DFLSGRPFYKDVNEC------KVFPGLCTH-GTCRNTVGSFHCACA 1014
Query: 428 AGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAG-----RTCSLD 475
G+ R+C T++D+C C G TC++ F C C GY + C +D
Sbjct: 1015 GGFALDAQERNC-TDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MD 1071
Query: 476 VDDCAPRPCTN-GGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAAC 528
VD+CA P GG C + +Y+C CP G GT CE D D C+ S C +G C
Sbjct: 1072 VDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG-QC 1129
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C G+ ++ DR+ C V + E R G C C+ EGS+R
Sbjct: 1130 VNVIGAFQCSCHAGF-------QSTPDRQGC-VDINEC-RVQNGGC--DVHCINTEGSYR 1178
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGA----LC 644
G C + +P G C C +G C
Sbjct: 1179 CSCGQGYSLMPDGRACADVDECEENPRVCDQGHC--TNMPGGHRCLCYDGFMATPDMRTC 1236
Query: 645 ELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGW 677
+ +D C +P C +G C G ++C C G+
Sbjct: 1237 -VDVDECDLNPHICLHGD-CENTKGSFVCHCQLGY 1269
Score = 96.3 bits (229), Expect = 5e-19
Identities = 99/362 (27%), Positives = 138/362 (38%), Gaps = 49/362 (13%)
Query: 242 QCQPYPG-CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCGTHEPCQHGGTCENT 294
+CQ PG C+ G C + S+ C C + +C+ D++ C TH GTC NT
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNT 1624
Query: 295 APDQYFCRCAEGFSGVDCERVDNPCAPQPC---AHGTC--SLAGTTRGFTCTCDRGWGGX 349
Y C C + V+ C +GTC LA C C G
Sbjct: 1625 L-GNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
+ C + GF D TG D+DEC G +
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGF---LTDIHTGKPL--DIDEC-------GEIPAI 1731
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
C N G + C C AG+ CE +VD+C + C A CI++ + C
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCK 1790
Query: 463 CAAGY---AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DR 514
C GY G C + ++C P C++ G+C+D +Y C+C GF + + D
Sbjct: 1791 CTRGYKLSPGGAC-VGRNECREIPNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMC 574
D C PCGNG C Y C C PG+ + D C+ LV + C G C
Sbjct: 1849 DECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTH--NGDCVDFDECTTLV--GQVCRFGHC 1903
Query: 575 AN 576
N
Sbjct: 1904 LN 1905
Score = 94.7 bits (225), Expect = 1e-18
Identities = 121/471 (25%), Positives = 171/471 (36%), Gaps = 85/471 (18%)
Query: 186 GHYSCTPDGDKHCLPGWQG--DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWR----GEL 239
G + C+ P QG D E V GC + C C G+ G
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 240 CS---QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------G 289
C+ +C+ P C G+C C + G + D+ C + C G
Sbjct: 1194 CADVDECEENPRVCDQGHCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHG 1252
Query: 290 TCENTAPDQYFCRCAEGF----SGVDCERVDN-PCAPQPC-AHGTC-SLAGTTRGFTCTC 342
CENT + C C G+ C VD C +H +C ++ G+ F+C C
Sbjct: 1253 DCENTK-GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS---FSCRC 1308
Query: 343 DRGWGGXXXXXXXXXXASGP---CLHGASCRDHLDGFTCECADGWTGPAC-AEDVDECSG 398
GW G C C + + C C G+ G ED DEC+
Sbjct: 1309 LPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAE 1368
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT-GQCLHGATCI 453
+ C N C N GGY C C G+ R C+ +VD+C G +C
Sbjct: 1369 N------VDLCDNGQ-CLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCE 1420
Query: 454 DLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGF--- 505
+L F C C GY G C+ D+++CA P C NG C++ +Y C CP F
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCING-VCINTPGSYLCSCPQDFELN 1478
Query: 506 -SGTNCEDDR-DHC---------AGSPCGNGAACYTAQSDYYCHCAPGWTGKNC----TQ 550
SG C D R +C +G C ++ C W G C
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMA 1537
Query: 551 RAARDRKTC-----------SVLVEESERCAE--GMCANGGTCVREEGSWR 588
R C +V++E+ + C E G+C GG CV GS++
Sbjct: 1538 NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNTFGSFQ 1587
Score = 90.6 bits (215), Expect = 2e-17
Identities = 110/408 (26%), Positives = 152/408 (37%), Gaps = 77/408 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 2121 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 2237
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 2238 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 2353
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 2412
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 2471
Query: 501 CPVGFSGTN--CEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAPGWT 544
CP GF+ + C D+ D C+ PCG C+ + C C G+T
Sbjct: 2472 CPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Score = 86.2 bits (204), Expect = 5e-16
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 61/395 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX--ASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC HG C + + C C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCY 475
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC DVDEC + G L C + C NT G + C C AG+ G+
Sbjct: 476 PGFQATPTRQACV-DVDEC----IVSGGL--C-HLGRCVNTEGSFQCVCNAGFELSPDGK 527
Query: 434 DCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDC-APRPCTNG 487
+C + + T C++G C++ F C C G+ G C +D+D+C P C NG
Sbjct: 528 NCVDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNG 585
Query: 488 GECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAGS----PCGNGAACYTAQSDYYC 537
C + ++RC C VG G C D R C G+ C +S+ C
Sbjct: 586 -HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 538 HCAPGWTGKNC----TQRAARDRKTCSVLV------EESERCA--EGMCANGGTCVREEG 585
G+ C + +A + CS + + CA +CAN G C G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRG 703
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTG 641
S+R G C S P ++C C G +
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDT 761
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
+C+ +D C SSPC + G C +G + C+C G
Sbjct: 762 EICK-DVDECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 83.8 bits (198), Expect = 3e-15
Identities = 101/382 (26%), Positives = 142/382 (37%), Gaps = 65/382 (17%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGE--LC---SQC--QPYPGCKHGYCNG--S 257
C+ G H +H C + PG C C PGW G+ C +C Q + G C
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 258 SWDCTCDTNWGG--ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---- 311
S+ CTC + G C+ D + C + G C N AP Y C C GF +
Sbjct: 1344 SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLN-APGGYRCECEMGFDPTEDHRA 1401
Query: 312 CERVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHG 366
C+ VD CA G+C +L G F C C+ G+ GG C++G
Sbjct: 1402 CQDVDECAQGNLCAFGSCENLPGM---FRCICNGGYELDRGGGNCTDINECADPVNCING 1458
Query: 367 ASCRDHLDGFTCECADGWT-GPACAEDVDECSGRSMTE----GALGPCVNAAACNNTAGG 421
C + + C C + P+ VD +G E G G +A
Sbjct: 1459 V-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 422 YSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DV 476
C L G CE C T ++ C G + + D+
Sbjct: 1518 SCCCSLGRAWGNPCEL--------CPMANTT-----EYRTLCPGGEGFQPNRITVILEDI 1564
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCA--GSPCGNGAACYT 530
D+C P GG+CV+ +++C CP G+ T +D D C+ S CG G CY
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPG-TCYN 1623
Query: 531 AQSDYYCHCAPGWT----GKNC 548
+Y C C + G NC
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNC 1645
Score = 81.4 bits (192), Expect = 1e-14
Identities = 87/302 (28%), Positives = 126/302 (41%), Gaps = 52/302 (17%)
Query: 201 GWQGDNCEKPVCKEGCHP-THGRC-DRPGD--CDCRPGWRGELCS-------QCQPYPGC 249
G+ + + C+ H HG C + G C C+ G+ + + +C P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 250 KHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPC---QHGGT--CENTAPDQYFCR 302
C + S+ C+C G L ++D C + C QH C NT + CR
Sbjct: 2416 CTFLCKNTKGSFLCSCPR---GYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV-GAFTCR 2471
Query: 303 CAEGFSGVDCERVDNP-CA--PQPC-AHGTCSLAGTTRGFTCTCDRGWG--GXXXXXXXX 356
C GF+ DN C+ P PC AHG C T F C C +G+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCH--NTPGSFRCECHQGFTLVSSGHGCEDV 2529
Query: 357 XXASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNA 412
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +
Sbjct: 2530 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGS 2581
Query: 413 AACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAA 465
A+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C
Sbjct: 2582 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQ 2638
Query: 466 GY 467
GY
Sbjct: 2639 GY 2640
Score = 76.2 bits (179), Expect = 5e-13
Identities = 93/371 (25%), Positives = 135/371 (36%), Gaps = 53/371 (14%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGELCS--QCQPYPG--CKHGYC- 254
D C++ C G C G + C C PG+ G+ +C G C+ G+C
Sbjct: 1849 DECDRQPCGNGTCKNIIGSYN----CLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL 1904
Query: 255 -NGSSWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
S+ C C + G C D N C + GTC+N + C C GF
Sbjct: 1905 NTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQN-LEGSFRCICPPGFQV 1962
Query: 310 VDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+D + C+ +P C GTC+ + F C C G+ C
Sbjct: 1963 QSDHCIDIDECSEEPNLCLFGTCT--NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-- 2018
Query: 367 ASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
R + A T C C + EG PC + A C
Sbjct: 2019 --TRFEAGKCSVPKAFNTTKTRC------CCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 427 LAGWT--GRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVD 477
G D +V++C G C +G C++ F C C GY+ G C +D D
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINC-VDTD 2128
Query: 478 DCA-PRPCTNGGECVDLLNAYRCICPVGFSG---TNCEDDRDHCAGSPCGNGAACYTAQS 533
+C+ PC G C +++ + C C GF CE D D C+ +P C+ +
Sbjct: 2129 ECSVGHPC-GQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEG 2186
Query: 534 DYYCHCAPGWT 544
Y C C G+T
Sbjct: 2187 SYLCTCPAGYT 2197
Score = 75.4 bits (177), Expect = 1e-12
Identities = 120/479 (25%), Positives = 166/479 (34%), Gaps = 96/479 (20%)
Query: 255 NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGV 310
N + + C + G +D+N C G CEN Y C C G+ SG
Sbjct: 662 NSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGK 720
Query: 311 DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRG---WGGXXXXXXXXXXASGPCLH 365
DC VD CA C +G C + ++C+C G W S PC+
Sbjct: 721 DCTDVDE-CALNSLLCDNGWCQ--NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS 777
Query: 366 GASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYS-- 423
G CR+ +TC+C GP D T+G + + C G S
Sbjct: 778 GV-CRNLAGSYTCKC-----GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 424 ---CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVD 477
CA L G CE +C + ACA G+A G TC DV+
Sbjct: 832 SECCATLGAAWGSPCE--------RC-----------EIDPACARGFARMTGVTCD-DVN 871
Query: 478 DCA--PRPCTNGGECVDLLNAYRCICPVGF----SGTNCED----------DRDHCAGS- 520
+C P C N G CV+ ++RC CP G SG C D D D C +
Sbjct: 872 ECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTL 930
Query: 521 P---------CGNGA-------ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVE 564
P C GA AC +S + P G A+RD + +
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLG-----FASRDFLSGRPFYK 985
Query: 565 ESERCA--EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTC 622
+ C G+C + GTC GS+ + GTC
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 623 LPSALPPGWACGCREG-RTGALCE---LSLDLCGSSPCRN-GGRCVGGSGWWMCECVAG 676
+ + P + C C G +G + + +D C P GG C G + C+C G
Sbjct: 1045 VNT--PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPG 1101
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/231 (27%), Positives = 82/231 (35%), Gaps = 57/231 (24%)
Query: 318 PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
P + C G CS CTC G S C++G +CR G +
Sbjct: 84 PICRRACGEGFCSQPNL-----CTCADGTLAPSCGVSRGSGCSVSCMNGGTCR----GAS 134
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C G+TG C + + C G C N C G CAC+ G+ G CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD-----RG----CHNGGRC---IGPNRCACVYGFMGPQCER 180
Query: 438 N--VDDCTGQ-----CLHGATCIDLVDDFHCACAAGYAGRTCSL---------------- 474
+ C GQ C H T + CA G C L
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
DVD+C P GG CV+++ ++ C CPVG S CED R
Sbjct: 241 HTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Score = 59.3 bits (137), Expect = 7e-08
Identities = 66/236 (27%), Positives = 87/236 (36%), Gaps = 46/236 (19%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C CA+G C C +G GT RG +C C +G+ G
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNG-----GTCRGASCLCQKGYTGTVCGQPICDRG- 154
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAED--VDECSGRSMTEGA----LGPCVNAAA 414
C +G C + C C G+ GP C D C G+ EG G A
Sbjct: 155 --CHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 415 CNNTAG---GYSCA--------CLAGW-----TGRDCETNVDDCT---GQCLHGATCIDL 455
C T G G C C G+ TG C+ +VD+C G C G +C+++
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLC-QGGSCVNM 266
Query: 456 VDDFHCACAAGYAGRTCSLDVDDCAPRPCTN---GGECV-DLLNAY---RCICPVG 504
V FHC C G+ S +D C + GG C DL Y +C C G
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 424 CACLAGWTGRDCETNVDD-CTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
C C G C + C+ C++G TC C C GY G C + D R
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD---R 153
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPC 522
C NGG C+ RC C GF G CE RD+ G PC
Sbjct: 154 GCHNGGRCI---GPNRCACVYGFMGPQCE--RDYRTG-PC 187
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 22/187 (11%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C G+ G C +P+C GCH GRC P C C G+ G C + + G C G
Sbjct: 137 CQKGYTGTVCGQPICDRGCH-NGGRCIGPNRCACVYGFMGPQCER-----DYRTGPCFGQ 190
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----SGVDC 312
C G++C + L C G CE + CR GF +G C
Sbjct: 191 VGPEGCQHQLTGLVCTKAL--CCATVGRAWGLPCELCPAQPHPCR--RGFIPNIHTGA-C 245
Query: 313 ERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC---LHGAS 368
+ VD P C G+C F C C G +G C L G
Sbjct: 246 QDVDECQAVPGLCQGGSC--VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGR 303
Query: 369 CRDHLDG 375
C L G
Sbjct: 304 CAGDLAG 310
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 533 SDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXX 592
S ++ +C PGW R R C V + C EG C+ C +G+
Sbjct: 62 SRFHAYCCPGW-------RTFPGRSQCVVPICR-RACGEGFCSQPNLCTCADGTLAPSCG 113
Query: 593 XXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCG 652
S GGTC G +C C++G TG +C +C
Sbjct: 114 VSRGSGCSVSCMN-------------GGTCR------GASCLCQKGYTGTVC--GQPICD 152
Query: 653 SSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C NGGRC+G + C CV G+ G C
Sbjct: 153 RG-CHNGGRCIGPN---RCACVYGFMGPQC 178
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKH-GYCNGSSWDCTCDTNWGGI 270
C C G C R C C+ G+ G +C Q GC + G C G + C C + G
Sbjct: 120 CSVSCM-NGGTC-RGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN-RCACVYGFMGP 176
Query: 271 LCDQDLNY--CGTH---EPCQHGGTCENTAPDQYFCRCAEGFS-GVDCERVDNPCAPQPC 324
C++D C E CQH T + C G + G+ CE P P PC
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCELC--PAQPHPC 232
Query: 325 AHG 327
G
Sbjct: 233 RRG 235
>AL359813-7|CAI23222.1| 134|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 134
Score = 123 bits (296), Expect = 4e-27
Identities = 50/121 (41%), Positives = 59/121 (48%), Gaps = 1/121 (0%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C+ G G C C HG C G C C PGW G C +C PGC+HG C+
Sbjct: 15 CILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-Q 73
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
W C C + W G CD+D + C T PCQ+GG C +Y C C GF G DCER
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG 133
Query: 318 P 318
P
Sbjct: 134 P 134
Score = 72.9 bits (171), Expect = 5e-12
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 187 HYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ---- 242
H C PDG C PGW+G +CE+ V GC HG C +P C C GW G+ C +
Sbjct: 37 HGCCAPDGSCRCDPGWEGLHCERCVRMPGCQ--HGTCHQPWQCICHSGWAGKFCDKDEHI 94
Query: 243 CQPYPGCKHG----YCNGSSWDCTCDTNWGGILCDQ 274
C C++G Y G + C C + G C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER 130
Score = 72.1 bits (169), Expect = 9e-12
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Query: 426 CLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C+ G G+ DDC+ C C D C C G+ G C + C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCC--APDGSCRCDPGWEGLHC----ERCVRMPGC 66
Query: 486 NGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAG-SPCGNGAAC-YTAQSDYYCHCAPGW 543
G C ++CIC G++G C+ D C SPC NG C Y +Y+C C PG+
Sbjct: 67 QHGTCHQ---PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGF 123
Query: 544 TGKNCTQRA 552
G++C ++A
Sbjct: 124 HGRDCERKA 132
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/124 (33%), Positives = 52/124 (41%), Gaps = 20/124 (16%)
Query: 314 RVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
R D+ + AHG C+ G+ C CD GW G C HG +C
Sbjct: 25 RADDCSSHCDLAHGCCAPDGS-----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQP- 74
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG-YSCACLAGWTG 432
+ C C GW G C +D C+ +S PC N C GG Y C CL G+ G
Sbjct: 75 --WQCICHSGWAGKFCDKDEHICTTQS-------PCQNGGQCMYDGGGEYHCVCLPGFHG 125
Query: 433 RDCE 436
RDCE
Sbjct: 126 RDCE 129
Score = 52.4 bits (120), Expect = 8e-06
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 243 CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C + HG C C CD W G+ C++ + G CQHG TC P Q C
Sbjct: 29 CSSHCDLAHGCC-APDGSCRCDPGWEGLHCERCVRMPG----CQHG-TCHQ--PWQ--CI 78
Query: 303 CAEGFSGVDCERVDNPCAPQ-PCAHGTCSLAGTTRGFTCTCDRGWGG 348
C G++G C++ ++ C Q PC +G + + C C G+ G
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHG 125
Score = 51.6 bits (118), Expect = 1e-05
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 631 WACGCREGRTGALCELSLDLCGS-SPCRNGGRCV-GGSGWWMCECVAGWTGETC 682
W C C G G C+ +C + SPC+NGG+C+ G G + C C+ G+ G C
Sbjct: 75 WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDC 128
Score = 50.4 bits (115), Expect = 3e-05
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 409 CVNAAACNNTA--GGYSCACLAGWTGRDCETNVDDCTGQ--CLHGATCI-DLVDDFHCAC 463
CV C + + C C +GW G+ C+ + CT Q C +G C+ D ++HC C
Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 464 AAGYAGRTC 472
G+ GR C
Sbjct: 120 LPGFHGRDC 128
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 122 bits (294), Expect = 6e-27
Identities = 130/491 (26%), Positives = 192/491 (39%), Gaps = 78/491 (15%)
Query: 242 QCQPYPG-CKHGYCNG--SSWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTA 295
+C+ PG C++G C S+ C C + +L +D++ C CQ C NTA
Sbjct: 1900 ECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA 1959
Query: 296 PDQYFCRCAEGFSGVDCERVD--NPC--APQPCAHGTCSLAGTTRGFTCTCDRGW--GGX 349
Y C C G+ + + N C P C+HG C T F C C G+
Sbjct: 1960 -GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC--IDTVGSFYCLCHTGFKTNDD 2016
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGAL 406
+CR+ + F C C G+ C DVDEC+ + G L
Sbjct: 2017 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI-DVDECASGN---GNL 2072
Query: 407 GPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDC---TGQCLHGATCIDLVDDF 459
C N C NT G + C C G+ GR C ++++C +C G TC +L +
Sbjct: 2073 --CRN-GQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSY 2127
Query: 460 HCACAAGYA--GRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCE 511
C C GY+ C D+D+C P C G C + +++C+CP GF SG C+
Sbjct: 2128 RCICPPGYSLQNEKCE-DIDECVEEPEICAL-GTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2185
Query: 512 DDR-DHCAGSPCGNGAACYTAQSDYY----CHCA---PGWTGKNC----TQRAARDRKTC 559
D R +C G C + +S + C CA GW G C T+ R+ C
Sbjct: 2186 DLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAFRQIC 2242
Query: 560 ----SVLV------EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++V + + C E G C+ +GS+R +
Sbjct: 2243 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECS 2302
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGCREG-RTGAL--CELSLDLCGSSPCRNGGRCVGGS 666
GTC + G+ C C EG G + CE ++ C +P RCV
Sbjct: 2303 VGNPC---GNGTC--KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTY 2356
Query: 667 GWWMCECVAGW 677
G + C+C G+
Sbjct: 2357 GSYECKCPVGY 2367
Score = 115 bits (276), Expect = 1e-24
Identities = 93/341 (27%), Positives = 142/341 (41%), Gaps = 53/341 (15%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
CD GW G C C P+ G ++ C G + D++ C H+ C++
Sbjct: 2496 CDGGRGW-GPHCEIC-PFQGTV-------AFKKLCPHGRGFMTNGADIDECKVIHDVCRN 2546
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPC--APQPCAHGTCSLAGTTRGFTCT 341
G C N Y C C G++ G C + N C AP+PC + C T + C+
Sbjct: 2547 G-ECVNDR-GSYHCICKTGYTPDITGTSCVDL-NECNQAPKPC-NFICK--NTEGSYQCS 2600
Query: 342 CDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C +G+ G C C + + GFTC+C G+T + C
Sbjct: 2601 CPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPGFT-----QHHTSC 2653
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTG--QCLHGA 450
+ + C + C NT G ++C C G+ TG CE +VD+C G +C HG
Sbjct: 2654 IDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG- 2711
Query: 451 TCIDLVDDFHCACAAGYAGR---TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS- 506
C +++ + C+C GY +D ++C G C + L +Y+C+CP GF
Sbjct: 2712 -CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQY 2770
Query: 507 ---GTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C+D + A +PC G C + Y C C PG+
Sbjct: 2771 EQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLCGCPPGY 2809
Score = 114 bits (275), Expect = 1e-24
Identities = 108/396 (27%), Positives = 159/396 (40%), Gaps = 54/396 (13%)
Query: 205 DNCEKP--VCKEG-CHPTHG--RCDRPGDCDCRPGWRGEL-CSQCQPYPG-CKHGYCNG- 256
D C++ +C+ G CH T G RC+ P P + ++C+ C +G C
Sbjct: 1246 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1305
Query: 257 -SSWDCTCDTNWGGILCDQDLNYCGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGV- 310
+ C C+ G D +C + C G CE + Y C C GF+ +
Sbjct: 1306 IGKYQCACNP---GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1362
Query: 311 ---DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP 362
C +D C P C G C+ + C C G+ P
Sbjct: 1363 DQRSCTDIDE-CEDNPNICDGGQCT--NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNP 1419
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
CL G +C + F C C G++G + C+ + E C A C NTAG
Sbjct: 1420 NICLSG-TCENTKGSFICHCDMGYSGK---KGKTGCTDINECEIGAHNCGKHAVCTNTAG 1475
Query: 421 GYSCACLAGWTGRDCE-TNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAGR--TCSL 474
+ C+C GW G + T++D+C T C A C + + + C C GY G TC+
Sbjct: 1476 SFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCT- 1534
Query: 475 DVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAAC 528
D+D+C+ C N G+C++ YRC C +GF G CED + + C G C
Sbjct: 1535 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFG-TC 1592
Query: 529 YTAQSDYYCHCAPGW----TGKNCTQ-RAARDRKTC 559
+ + C C G+ +G NCT D TC
Sbjct: 1593 HNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTC 1628
Score = 111 bits (268), Expect = 9e-24
Identities = 129/513 (25%), Positives = 189/513 (36%), Gaps = 68/513 (13%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQC--QPYPGCKHGYCN 255
C ++ + C P+ G H C C W E C +C + P +
Sbjct: 1089 CFLRYEDEECTLPIA--GRHRMDACC-----CSVGAAWGTEECEECPMRNTPEYEELCPR 1141
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GV 310
G + TN G +D+N C C HG C NT + CRC GF+
Sbjct: 1142 GPGFATKEITN--GKPFFKDINECKMIPSLCTHG-KCRNTI-GSFKCRCDSGFALDSEER 1197
Query: 311 DCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----GPCL- 364
+C +D +P C G C T F C CD G+ P L
Sbjct: 1198 NCTDIDECRISPDLCGRGQC--VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 1255
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C + + CEC G + ++ C + E + C N C N G Y C
Sbjct: 1256 RGGVCHNTEGSYRCECP---PGHQLSPNISACIDINECELSAHLCPN-GRCVNLIGKYQC 1311
Query: 425 ACLAGW---TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSL 474
AC G+ R ++D+C+ G C C + + C+C G+A R+C+
Sbjct: 1312 ACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCT- 1368
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAA 527
D+D+C P +GG+C ++ YRC+C GF + C D + C +P C +G
Sbjct: 1369 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE-CDLNPNICLSG-T 1426
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + CHC G++GK KT + E E A C C GS+
Sbjct: 1427 CENTKGSFICHCDMGYSGKK--------GKTGCTDINECEIGAHN-CGKHAVCTNTAGSF 1477
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG-ALCEL 646
+ Q C + + C C+EG TG
Sbjct: 1478 KCSCSPGWIGDGIKCTDLDECSNGTHMCSQ-HADCKNTM--GSYRCLCKEGYTGDGFTCT 1534
Query: 647 SLDLCGS--SPCRNGGRCVGGSGWWMCECVAGW 677
LD C + C N G+C+ G + CEC G+
Sbjct: 1535 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGF 1566
Score = 111 bits (266), Expect = 2e-23
Identities = 114/397 (28%), Positives = 153/397 (38%), Gaps = 75/397 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHG 221
C P Y++T FC D+ + C + C C C+ G P
Sbjct: 1313 CNPGYHSTPDRLFCVDIDECSIMNGGC----ETFCTNSEGSYECS---CQPGFALMPDQR 1365
Query: 222 RCDRPGDCDCRPGWRGELC--SQCQPYPG-----CKHGYCNGSSWDCTCDTNWGGILCDQ 274
C +C+ P +C QC PG C G+ D N CD
Sbjct: 1366 SCTDIDECEDNP----NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDL 1417
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPC--APQPCA-HG 327
+ N C GTCENT + C C G+SG C + N C C H
Sbjct: 1418 NPNIC-------LSGTCENT-KGSFICHCDMGYSGKKGKTGCTDI-NECEIGAHNCGKHA 1468
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG---PCLHGASCRDHLDGFTCECADGW 384
C+ T F C+C GW G S C A C++ + + C C +G+
Sbjct: 1469 VCT--NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1526
Query: 385 TGPA-CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNV 439
TG D+DECS L C N C N GGY C C G+ G+ CE ++
Sbjct: 1527 TGDGFTCTDLDECSEN------LNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACE-DI 1578
Query: 440 DDCT--GQCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVD 492
D+C+ C+ G TC +L F C C GY +G C+ DV++C P C + G CV+
Sbjct: 1579 DECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCIS-GNCVN 1635
Query: 493 LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
+Y C CP F R C + GN CY
Sbjct: 1636 TPGSYICDCPPDF---ELNPTRVGCVDTRSGN---CY 1666
Score = 110 bits (264), Expect = 3e-23
Identities = 126/446 (28%), Positives = 175/446 (39%), Gaps = 87/446 (19%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW---RGELC---SQCQPYPG--CKHGYCN 255
+ CE+ C G C T G + C C G+ C +C G C++G C
Sbjct: 2024 NECERDACGNGTCRNTIGSFN----CRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI 2079
Query: 256 GS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS- 308
+ S+ C C+ + G C D+N C GTC+N Y C C G+S
Sbjct: 2080 NTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNL-DGSYRCICPPGYSL 2137
Query: 309 -GVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC-- 363
CE +D C +P CA GTCS T F C C G+ C
Sbjct: 2138 QNEKCEDIDE-CVEEPEICALGTCS--NTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYA 2194
Query: 364 -LHGASC-----RDHLDGFTCECA---DGWTGPA--CAEDVDECSGRSMTEGA---LGPC 409
G C R+H C CA +GW P C + DE + G+ +GP
Sbjct: 2195 KFEGGKCSSPKSRNHSKQECC-CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 2253
Query: 410 VNAA--------------ACNNTAGGYSCACLAGWT--GRDCETNVDDCT-GQCLHGATC 452
+A C NT G Y C C G+T G +C + D+C+ G TC
Sbjct: 2254 DSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNEC-VDTDECSVGNPCGNGTC 2312
Query: 453 IDLVDDFHCACAAGYAG---RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF---- 505
+++ F C C G+ TC D+++CA P CV+ +Y C CPVG+
Sbjct: 2313 KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLRE 2371
Query: 506 SGTNCEDDRDHC--AGSPC-GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
C+D+ D C C C Y C C PG+ QR D + C
Sbjct: 2372 DRRMCKDE-DECEEGKHDCTEKQMECKNLIGTYMCICGPGY------QRRP-DGEGC--- 2420
Query: 563 VEESE-RCAEGMCANGGTCVREEGSW 587
V+E+E + G+C N G C+ GS+
Sbjct: 2421 VDENECQTKPGICEN-GRCLNTRGSY 2445
Score = 107 bits (258), Expect = 1e-22
Identities = 94/326 (28%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCS 330
D++ C G C N + C C GF D CE +D C P
Sbjct: 1897 DIDECREIPGVCENGVCINMV-GSFRCECPVGFFYNDKLLVCEDIDE-CQNGPVCQRNAE 1954
Query: 331 LAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
T + C C G+ G C HG C D + F C C TG
Sbjct: 1955 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCLCH---TG 2010
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDDCT 443
+D C + E C N C NT G ++C C G+ DC +VD+C
Sbjct: 2011 FKTNDDQTMCL--DINECERDACGNGT-CRNTIGSFNCRCNHGFILSHNNDC-IDVDECA 2066
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTNGGECVDLL 494
G CI+ V F C C GY GRTC +D+++C PR C G C +L
Sbjct: 2067 SGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLD 2124
Query: 495 NAYRCICPVGFSGTN--CEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+YRCICP G+S N CE D D C P C G C + + C C G++ + +
Sbjct: 2125 GSYRCICPPGYSLQNEKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGR 2182
Query: 551 RAARDRKTCSVLVEESERCAEGMCAN 576
R R + E +C+ N
Sbjct: 2183 RCQDLRMSYCYAKFEGGKCSSPKSRN 2208
Score = 98.7 bits (235), Expect = 9e-20
Identities = 130/511 (25%), Positives = 189/511 (36%), Gaps = 81/511 (15%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR--GELC---SQCQPYPGCKHGYCNG- 256
D C++P VCK G C T G C+C G+ G C +C C +G C
Sbjct: 2260 DECKEPDVCKHGQCINTDGSYR----CECPFGYTLAGNECVDTDECSVGNPCGNGTCKNV 2315
Query: 257 -SSWDCTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
++CTC+ + G ++ +D+N C + P C NT Y C+C G+ +
Sbjct: 2316 IGGFECTCEEGFEPGPMMTCEDINECAQN-PLLCAFRCVNTY-GSYECKCPVGYVLREDR 2373
Query: 314 RV---DNPC--APQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPC 363
R+ ++ C C + C C G+ G G C
Sbjct: 2374 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2433
Query: 364 LHGASCRDHLDGFTCECADGWTG-PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
+G C + +TCEC DG+T P E +D G TE C ++ N
Sbjct: 2434 ENGR-CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2492
Query: 423 SCACLAG--WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G W G CE C Q G F C G T D+D+C
Sbjct: 2493 ECCCDGGRGW-GPHCEI----CPFQ---GTVA------FKKLCPHGRGFMTNGADIDECK 2538
Query: 481 P--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C NG ECV+ +Y CIC G+ +GT+C D + C +P C +
Sbjct: 2539 VIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTSCV-DLNECNQAPKPCNFICKNTEGS 2596
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN---GGTCVREEGSWRXXX 591
Y C C G+ + R+ +D C+ + C + +C N G TC G
Sbjct: 2597 YQCSCPKGYILQE-DGRSCKDLDECAT---KQHNC-QFLCVNTIGGFTCKCPPG------ 2645
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
S + G C P + C C+ G +TG+ CE
Sbjct: 2646 ----FTQHHTSCIDNNECTSDINLCGSKGIC--QNTPGSFTCECQRGFSLDQTGSSCE-D 2698
Query: 648 LDLC-GSSPCRNGGRCVGGSGWWMCECVAGW 677
+D C G+ C++G C G + C C G+
Sbjct: 2699 VDECEGNHRCQHG--CQNIIGGYRCSCPQGY 2727
Score = 98.3 bits (234), Expect = 1e-19
Identities = 115/410 (28%), Positives = 158/410 (38%), Gaps = 94/410 (22%)
Query: 205 DNCEK-PVCKEG--CHPTHGRCDRPGDCDCRPGWR----GEL--CSQCQPYPG-CKHGYC 254
D C+ PVC+ C T G CDC+PG+R G+ ++CQ P C HG C
Sbjct: 1941 DECQNGPVCQRNAECINTAGSYR----CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC 1996
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----GGTCENTAPDQYFCRCAEGF- 307
S+ C C T G + D C C+ GTC NT + CRC GF
Sbjct: 1997 IDTVGSFYCLCHT---GFKTNDDQTMCLDINECERDACGNGTCRNTI-GSFNCRCNHGFI 2052
Query: 308 --SGVDCERVDNPCAP---QPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXX 357
DC VD CA C +G C T F C C+ G+ G
Sbjct: 2053 LSHNNDCIDVDE-CASGNGNLCRNGQC--INTVGSFQCQCNEGYEVAPDGRTCVDINECL 2109
Query: 358 XASGPCLHGASCRDHLDG-FTCECADGWT--GPACAEDVDECSGRSMTEGALGPCVNAAA 414
C G +C+ +LDG + C C G++ C ED+DEC + E + C
Sbjct: 2110 LEPRKCAPG-TCQ-NLDGSYRCICPPGYSLQNEKC-EDIDEC----VEEPEI--CA-LGT 2159
Query: 415 CNNTAGGYSCACLAGW----TGRDC-ETNVDDCTGQCLHGATCIDLVDDFH----CACAA 465
C+NT G + C C G+ +GR C + + C + G C H C CA
Sbjct: 2160 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK-FEGGKCSSPKSRNHSKQECCCAL 2218
Query: 466 GYAG-----RTCSLDVDDCAPRPCTNG-------------------------GECVDLLN 495
G C + D+ + C G G+C++
Sbjct: 2219 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 2278
Query: 496 AYRCICPVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+YRC CP G+ +G C D + G+PCGNG C + C C G+
Sbjct: 2279 SYRCECPFGYTLAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGF 2327
Score = 93.9 bits (223), Expect = 3e-18
Identities = 101/375 (26%), Positives = 140/375 (37%), Gaps = 61/375 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C PGW GD + E + TH C + DC G +C CK GY G
Sbjct: 1481 CSPGWIGDGIKCTDLDECSNGTH-MCSQHADCKNTMG-----SYRCL----CKEGY-TGD 1529
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCE 313
+ CT D + C ++LN CG G C N AP Y C C GF G CE
Sbjct: 1530 GFTCT-DLDE----CSENLNLCGN-------GQCLN-APGGYRCECDMGFVPSADGKACE 1576
Query: 314 RVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGAS 368
+D P C GTC +L G F C C+ G+ G C+ G +
Sbjct: 1577 DIDECSLPNICVFGTCHNLPGL---FRCECEIGYELDRSGGNCTDVNECLDPTTCISG-N 1632
Query: 369 CRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
C + + C+C D P VD SG + AC+N G
Sbjct: 1633 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIG------- 1685
Query: 428 AGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DVDDCAPR 482
G + C ++ G ++ ++ C G R + D+D+C
Sbjct: 1686 VGVSKASCCCSLGKAWGTPCEMCPAVN-TSEYKILCPGGEGFRPNPITVILEDIDECQEL 1744
Query: 483 P-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYC 537
P GG+C++ +++C CP G+ T DD + C CG G CY +Y C
Sbjct: 1745 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT-CYNTVGNYTC 1803
Query: 538 HCAPGWT----GKNC 548
C P + G NC
Sbjct: 1804 ICPPDYMQVNGGNNC 1818
Score = 93.1 bits (221), Expect = 4e-18
Identities = 131/510 (25%), Positives = 181/510 (35%), Gaps = 80/510 (15%)
Query: 220 HGRC-DRPGD--CDCRPGW----RGEL--CSQCQPYPGCKHGYC--NGSSWDCTCDTNWG 268
+GRC PG C+C G+ RGE +C+ P C G C N S+ C C +
Sbjct: 593 NGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQGSYTCQCRAGYQ 651
Query: 269 GILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAP 321
L +D++ C + + G C NT + C C GF G +CE +D
Sbjct: 652 STLTRTECRDIDECLQNGRICNNGRCINT-DGSFHCVCNAGFHVTRDGKNCEDMDECSIR 710
Query: 322 QPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
C +G C F C C G+ G G C++G C + +
Sbjct: 711 NMCLNGMC--INEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYR 767
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGAL--GPCVNAAACNNTAGGYSCACLAGWTGRDC 435
CEC G + RS G G C+ T CA G C
Sbjct: 768 CECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC 827
Query: 436 ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDL 493
+ C Q + A ++ C++G + D+++CA P C N G C +L
Sbjct: 828 Q----PCPAQ--NSA-------EYQALCSSGPGMTSAGSDINECALDPDICPN-GICENL 873
Query: 494 LNAYRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
Y+CIC G+ +G NC D + S C NG C + C C G+ K
Sbjct: 874 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIYK-- 930
Query: 549 TQRAARDRKTCSVLVE-ESERCAEGMCANG-GTCVREEGSWRXXXXXXXXXXXXDSXXXX 606
D KTC + E ES C G+C N G+ + E S
Sbjct: 931 -----PDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCW 985
Query: 607 XXXXXXXXXXQAGGTCLP----SALPPGWA-----------CGCREGR-TGALCELSLDL 650
G L S+L W CG R G CE +D
Sbjct: 986 QTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDE 1044
Query: 651 CGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
C P C+N G CV G + C+C +G T
Sbjct: 1045 CEVFPGVCKN-GLCVNTRGSFKCQCPSGMT 1073
Score = 91.9 bits (218), Expect = 1e-17
Identities = 106/393 (26%), Positives = 151/393 (38%), Gaps = 63/393 (16%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C++G+ PC G C ++ +TC+C
Sbjct: 591 CQNGRC--IPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQCR 647
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGR 433
G+ T C D+DEC + G + C N C NT G + C C AG+ G+
Sbjct: 648 AGYQSTLTRTEC-RDIDEC----LQNGRI--C-NNGRCINTDGSFHCVCNAGFHVTRDGK 699
Query: 434 DCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDC-APRPCTN 486
+CE ++D+C+ CL+G CI+ F C C G+ GR C D+++C P C N
Sbjct: 700 NCE-DMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMN 756
Query: 487 GGECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAG----SPCGNGAACYTAQSDYY 536
G CV+ +YRC C VG G C D R C G C +S+
Sbjct: 757 G-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECC 815
Query: 537 CHCAPGWTGKNC----TQRAARDRKTCS------VLVEESERCA--EGMCANGGTCVREE 584
C G+ C Q +A + CS + CA +C N G C
Sbjct: 816 CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLR 874
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RT 640
G+++ G C + P + C C +G
Sbjct: 875 GTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNT--PGSFVCTCPKGFIYKPD 932
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
CE +D C SSPC N G C G ++CEC
Sbjct: 933 LKTCE-DIDECESSPCIN-GVCKNSPGSFICEC 963
Score = 87.8 bits (208), Expect = 2e-16
Identities = 98/344 (28%), Positives = 128/344 (37%), Gaps = 68/344 (19%)
Query: 190 CTPDGDKHCLPGWQ----GDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C + +C PGW+ G+ C P+C+ C G C RP C C G C +
Sbjct: 190 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGD--GFCSRPNMCTCPSGQIAPSCGS-RS 246
Query: 246 YPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C NG S C C + G C Q + G C +GG C AP++ C
Sbjct: 247 IQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG----CLNGGRC--VAPNR--CA 298
Query: 303 CAEGFSGVDCER--VDNPC----APQPCAHGTCSLAGTTRGFTC-TCDRGWGGXXXXXXX 355
C GF+G CER PC + Q C G S T+ C T R WG
Sbjct: 299 CTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCCATVGRAWG-------- 349
Query: 356 XXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
PC + A GF G AC +DVDEC + G C
Sbjct: 350 -----HPCEMCPAQPHPCRRGFIPNIRTG----AC-QDVDEC------QAIPGLC-QGGN 392
Query: 415 CNNTAGGYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
C NT G + C C AG + CE ++D+C+ G C G C + V + C C G+
Sbjct: 393 CINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGIC-EGGECTNTVSSYFCKCPPGF 450
Query: 468 AGRTCSLDVDDCAPRPC----TNG---GECVDLLNAYRCICPVG 504
D P C TNG + + +C C G
Sbjct: 451 YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 494
Score = 83.4 bits (197), Expect = 4e-15
Identities = 73/265 (27%), Positives = 100/265 (37%), Gaps = 27/265 (10%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS--GVDCERVDNPCAPQPCAHGTCSLA 332
D++ C + C+HG C NT Y C C G++ G +C D PC +GTC
Sbjct: 2258 DMDECKEPDVCKHG-QCINT-DGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCK-- 2313
Query: 333 GTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACA 390
GF CTC+ G+ G A P L C + + C+C G+
Sbjct: 2314 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGY---VLR 2370
Query: 391 EDVDECSGRSMTEGALGPCV-NAAACNNTAGGYSCACLAGWTGR-DCETNVD--DC---T 443
ED C E C C N G Y C C G+ R D E VD +C
Sbjct: 2371 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2430
Query: 444 GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPV 503
G C +G C++ + C C G+ T S + D+C G C + +C +
Sbjct: 2431 GICENG-RCLNTRGSYTCECNDGF---TASPNQDECLD---NREGYC--FTEVLQNMCQI 2481
Query: 504 GFSGTNCEDDRDHCAGSPCGNGAAC 528
G S N + C G G C
Sbjct: 2482 GSSNRNPVTKSECCCDGGRGWGPHC 2506
Score = 82.2 bits (194), Expect = 8e-15
Identities = 99/365 (27%), Positives = 135/365 (36%), Gaps = 74/365 (20%)
Query: 231 CRPGWR----GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNYCGTHEPC 285
C PGW+ G C C G+C+ + CTC + C + + +C C
Sbjct: 198 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNM-CTCPSGQIAPSCGSRSIQHCNIR--C 254
Query: 286 QHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
+GG+C + C C +G+ G C + P C +G +A C C G
Sbjct: 255 MNGGSCSDD-----HCLCQKGYIGTHCGQ---PVCESGCLNGGRCVAPNR----CACTYG 302
Query: 346 WGGXXXXXXXXXXASGPC---LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR--S 400
+ G +GPC + C+ L G C T C V G
Sbjct: 303 FTGPQCERDYR---TGPCFTVISNQMCQGQLSGIVC------TKTLCCATVGRAWGHPCE 353
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVD 457
M PC N G AC +VD+C G C G CI+ V
Sbjct: 354 MCPAQPHPCRRGFIPNIRTG----AC----------QDVDECQAIPGLC-QGGNCINTVG 398
Query: 458 DFHCACAAGY----AGRTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGT 508
F C C AG+ + C D+D+C+ P GGEC + +++Y C CP GF GT
Sbjct: 399 SFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 457
Query: 509 NCEDDR-DHC----AGSPCGNGAACYTAQSDYYC---HC-APGWT--GKNCTQRAARD-R 556
C D R +C C N + C C +PG T + C RA D
Sbjct: 458 RCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFN 517
Query: 557 KTCSV 561
K CSV
Sbjct: 518 KLCSV 522
Score = 79.8 bits (188), Expect = 4e-14
Identities = 102/361 (28%), Positives = 136/361 (37%), Gaps = 70/361 (19%)
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQ--DLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C++G C S+ C C+ + L + D++ C + PC GG C N Y C+C
Sbjct: 591 CQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKN-PCA-GGECINNQ-GSYTCQCR 647
Query: 305 EGFSGV----DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXX 354
G+ +C +D C C +G C T F C C+ G+ G
Sbjct: 648 AGYQSTLTRTECRDIDE-CLQNGRICNNGRC--INTDGSFHCVCNAGFHVTRDGKNCEDM 704
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCV 410
CL+G C + F C C G+ G C +D++EC G C+
Sbjct: 705 DECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYC-KDINECE-------TPGICM 755
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDC-ETNV-DDCTGQCLHGATCIDL---VDDFHC 461
N C NT G Y C C G GR C +T++ C G G L V C
Sbjct: 756 NGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 814
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
CA+ T + C P P N E Y+ +C G T+ D + CA P
Sbjct: 815 CCAS-----TEYAFGEPCQPCPAQNSAE-------YQALCSSGPGMTSAGSDINECALDP 862
Query: 522 --CGNGAACYTAQSDYYCHCAPGW----TGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C NG C + Y C C G+ TGKNC D C V S C G C
Sbjct: 863 DICPNG-ICENLRGTYKCICNSGYEVDSTGKNCV-----DINEC---VLNSLLCDNGQCR 913
Query: 576 N 576
N
Sbjct: 914 N 914
Score = 77.4 bits (182), Expect = 2e-13
Identities = 111/474 (23%), Positives = 165/474 (34%), Gaps = 73/474 (15%)
Query: 237 GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
G C+ CQ P C GY C +D++ C G C NT
Sbjct: 1015 GSPCTLCQVDPICGKGYSRIKGTQC------------EDIDECEVFPGVCKNGLCVNTR- 1061
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPC------AHGTCSLAGTTRGFTCTCDRGWGGXX 350
+ C+C G + R+ + C T +AG R C C G
Sbjct: 1062 GSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGT 1121
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
+ P R GF + + G +D++EC +
Sbjct: 1122 EECEECPMRNTPEYEELCPRG--PGFATK--EITNGKPFFKDINECK-------MIPSLC 1170
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCAC 463
C NT G + C C +G+ R+C T++D+C C G C++ DF C C
Sbjct: 1171 THGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRG-QCVNTPGDFECKC 1228
Query: 464 AAGYAG-----RTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFS---GTNCEDDR 514
GY + C +D+D+C P GG C + +YRC CP G + D
Sbjct: 1229 DEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1287
Query: 515 DHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
+ C S C NG C Y C C PG+ + DR C V ++E G
Sbjct: 1288 NECELSAHLCPNG-RCVNLIGKYQCACNPGY-------HSTPDRLFC-VDIDECS-IMNG 1337
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA 632
C C EGS+ GG C + +P +
Sbjct: 1338 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1393
Query: 633 CGCREGRTGA----LCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTGE 680
C C +G + C + ++ C +P C + G C G ++C C G++G+
Sbjct: 1394 CLCYDGFMASEDMKTC-VDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGK 1445
Score = 65.7 bits (153), Expect = 8e-10
Identities = 61/226 (26%), Positives = 89/226 (39%), Gaps = 36/226 (15%)
Query: 474 LDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCAGSP-CGNGA 526
+D+D+C P C NG C++++ ++RC CPVGF + CE D D C P C A
Sbjct: 1896 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNA 1953
Query: 527 ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGS 586
C Y C C PG+ + Q DR C + +C++ G C+ GS
Sbjct: 1954 ECINTAGSYRCDCKPGYRFTSTGQ--CNDRNECQEI--------PNICSH-GQCIDTVGS 2002
Query: 587 WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG---RTGAL 643
+ D GTC + + C C G
Sbjct: 2003 F--YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTI--GSFNCRCNHGFILSHNND 2058
Query: 644 CELSLDLCGS---SPCRNGGRCVGGSGWWMCECVAGW----TGETC 682
C + +D C S + CRN G+C+ G + C+C G+ G TC
Sbjct: 2059 C-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTC 2102
Score = 56.4 bits (130), Expect = 5e-07
Identities = 50/199 (25%), Positives = 67/199 (33%), Gaps = 22/199 (11%)
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCED--DRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
C NG C+ +YRC C GF + D D C +PC G C Q Y C C
Sbjct: 591 CQNG-RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRA 648
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+ T+ RD C G N G C+ +GS+ D
Sbjct: 649 GYQS-TLTRTECRDIDEC---------LQNGRICNNGRCINTDGSFHCVCNAGFHVTR-D 697
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELSLDLCGSSPCR 657
G C+ + C C+ G G C+ ++ C +
Sbjct: 698 GKNCEDMDECSIRNMCLNGMCINE--DGSFKCICKPGFQLASDGRYCK-DINECETPGIC 754
Query: 658 NGGRCVGGSGWWMCECVAG 676
GRCV G + CEC G
Sbjct: 755 MNGRCVNTDGSYRCECFPG 773
Score = 43.6 bits (98), Expect = 0.004
Identities = 50/187 (26%), Positives = 66/187 (35%), Gaps = 19/187 (10%)
Query: 499 CICPVGFSGTNCEDDR-DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C CP G +C HC C NG +C SD +C C G+ G +C Q
Sbjct: 231 CTCPSGQIAPSCGSRSIQHC-NIRCMNGGSC----SDDHCLCQKGYIGTHCGQPVCESGC 285
Query: 558 TCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD-SXXXXXXXXXXXXXX 616
RCA G C R+ + S
Sbjct: 286 LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG 345
Query: 617 QAGGTCLPSALPPGWACGCREG-----RTGALCELSLDLCGSSP--CRNGGRCVGGSGWW 669
+A G P + P CR G RTGA C+ +D C + P C+ GG C+ G +
Sbjct: 346 RAWGH--PCEMCPAQPHPCRRGFIPNIRTGA-CQ-DVDECQAIPGLCQ-GGNCINTVGSF 400
Query: 670 MCECVAG 676
C+C AG
Sbjct: 401 ECKCPAG 407
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C++G G C +C S C NGGRCV + C C G+TG C
Sbjct: 265 CLCQKGYIGTHC--GQPVCESG-CLNGGRCVAPN---RCACTYGFTGPQC 308
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 122 bits (294), Expect = 6e-27
Identities = 130/491 (26%), Positives = 192/491 (39%), Gaps = 78/491 (15%)
Query: 242 QCQPYPG-CKHGYCNG--SSWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTA 295
+C+ PG C++G C S+ C C + +L +D++ C CQ C NTA
Sbjct: 1769 ECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA 1828
Query: 296 PDQYFCRCAEGFSGVDCERVD--NPC--APQPCAHGTCSLAGTTRGFTCTCDRGW--GGX 349
Y C C G+ + + N C P C+HG C T F C C G+
Sbjct: 1829 -GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC--IDTVGSFYCLCHTGFKTNDD 1885
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGAL 406
+CR+ + F C C G+ C DVDEC+ + G L
Sbjct: 1886 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI-DVDECASGN---GNL 1941
Query: 407 GPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDC---TGQCLHGATCIDLVDDF 459
C N C NT G + C C G+ GR C ++++C +C G TC +L +
Sbjct: 1942 --CRN-GQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSY 1996
Query: 460 HCACAAGYA--GRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCE 511
C C GY+ C D+D+C P C G C + +++C+CP GF SG C+
Sbjct: 1997 RCICPPGYSLQNEKCE-DIDECVEEPEICAL-GTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 512 DDR-DHCAGSPCGNGAACYTAQSDYY----CHCA---PGWTGKNC----TQRAARDRKTC 559
D R +C G C + +S + C CA GW G C T+ R+ C
Sbjct: 2055 DLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAFRQIC 2111
Query: 560 ----SVLV------EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++V + + C E G C+ +GS+R +
Sbjct: 2112 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECS 2171
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGCREG-RTGAL--CELSLDLCGSSPCRNGGRCVGGS 666
GTC + G+ C C EG G + CE ++ C +P RCV
Sbjct: 2172 VGNPC---GNGTC--KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTY 2225
Query: 667 GWWMCECVAGW 677
G + C+C G+
Sbjct: 2226 GSYECKCPVGY 2236
Score = 115 bits (276), Expect = 1e-24
Identities = 93/341 (27%), Positives = 142/341 (41%), Gaps = 53/341 (15%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
CD GW G C C P+ G ++ C G + D++ C H+ C++
Sbjct: 2365 CDGGRGW-GPHCEIC-PFQGTV-------AFKKLCPHGRGFMTNGADIDECKVIHDVCRN 2415
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPC--APQPCAHGTCSLAGTTRGFTCT 341
G C N Y C C G++ G C + N C AP+PC + C T + C+
Sbjct: 2416 G-ECVNDR-GSYHCICKTGYTPDITGTSCVDL-NECNQAPKPC-NFICK--NTEGSYQCS 2469
Query: 342 CDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C +G+ G C C + + GFTC+C G+T + C
Sbjct: 2470 CPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPGFT-----QHHTSC 2522
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTG--QCLHGA 450
+ + C + C NT G ++C C G+ TG CE +VD+C G +C HG
Sbjct: 2523 IDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG- 2580
Query: 451 TCIDLVDDFHCACAAGYAGR---TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS- 506
C +++ + C+C GY +D ++C G C + L +Y+C+CP GF
Sbjct: 2581 -CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQY 2639
Query: 507 ---GTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C+D + A +PC G C + Y C C PG+
Sbjct: 2640 EQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLCGCPPGY 2678
Score = 114 bits (275), Expect = 1e-24
Identities = 108/396 (27%), Positives = 159/396 (40%), Gaps = 54/396 (13%)
Query: 205 DNCEKP--VCKEG-CHPTHG--RCDRPGDCDCRPGWRGEL-CSQCQPYPG-CKHGYCNG- 256
D C++ +C+ G CH T G RC+ P P + ++C+ C +G C
Sbjct: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
Query: 257 -SSWDCTCDTNWGGILCDQDLNYCGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGV- 310
+ C C+ G D +C + C G CE + Y C C GF+ +
Sbjct: 1175 IGKYQCACNP---GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 311 ---DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP 362
C +D C P C G C+ + C C G+ P
Sbjct: 1232 DQRSCTDIDE-CEDNPNICDGGQCT--NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNP 1288
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
CL G +C + F C C G++G + C+ + E C A C NTAG
Sbjct: 1289 NICLSG-TCENTKGSFICHCDMGYSGK---KGKTGCTDINECEIGAHNCGKHAVCTNTAG 1344
Query: 421 GYSCACLAGWTGRDCE-TNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAGR--TCSL 474
+ C+C GW G + T++D+C T C A C + + + C C GY G TC+
Sbjct: 1345 SFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCT- 1403
Query: 475 DVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAAC 528
D+D+C+ C N G+C++ YRC C +GF G CED + + C G C
Sbjct: 1404 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFG-TC 1461
Query: 529 YTAQSDYYCHCAPGW----TGKNCTQ-RAARDRKTC 559
+ + C C G+ +G NCT D TC
Sbjct: 1462 HNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTC 1497
Score = 111 bits (268), Expect = 9e-24
Identities = 129/513 (25%), Positives = 189/513 (36%), Gaps = 68/513 (13%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQC--QPYPGCKHGYCN 255
C ++ + C P+ G H C C W E C +C + P +
Sbjct: 958 CFLRYEDEECTLPIA--GRHRMDACC-----CSVGAAWGTEECEECPMRNTPEYEELCPR 1010
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GV 310
G + TN G +D+N C C HG C NT + CRC GF+
Sbjct: 1011 GPGFATKEITN--GKPFFKDINECKMIPSLCTHG-KCRNTI-GSFKCRCDSGFALDSEER 1066
Query: 311 DCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----GPCL- 364
+C +D +P C G C T F C CD G+ P L
Sbjct: 1067 NCTDIDECRISPDLCGRGQC--VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 1124
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C + + CEC G + ++ C + E + C N C N G Y C
Sbjct: 1125 RGGVCHNTEGSYRCECP---PGHQLSPNISACIDINECELSAHLCPN-GRCVNLIGKYQC 1180
Query: 425 ACLAGW---TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSL 474
AC G+ R ++D+C+ G C C + + C+C G+A R+C+
Sbjct: 1181 ACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCT- 1237
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAA 527
D+D+C P +GG+C ++ YRC+C GF + C D + C +P C +G
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE-CDLNPNICLSG-T 1295
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + CHC G++GK KT + E E A C C GS+
Sbjct: 1296 CENTKGSFICHCDMGYSGKK--------GKTGCTDINECEIGAHN-CGKHAVCTNTAGSF 1346
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG-ALCEL 646
+ Q C + + C C+EG TG
Sbjct: 1347 KCSCSPGWIGDGIKCTDLDECSNGTHMCSQ-HADCKNTM--GSYRCLCKEGYTGDGFTCT 1403
Query: 647 SLDLCGS--SPCRNGGRCVGGSGWWMCECVAGW 677
LD C + C N G+C+ G + CEC G+
Sbjct: 1404 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGF 1435
Score = 111 bits (266), Expect = 2e-23
Identities = 114/397 (28%), Positives = 153/397 (38%), Gaps = 75/397 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHG 221
C P Y++T FC D+ + C + C C C+ G P
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECSIMNGGC----ETFCTNSEGSYECS---CQPGFALMPDQR 1234
Query: 222 RCDRPGDCDCRPGWRGELC--SQCQPYPG-----CKHGYCNGSSWDCTCDTNWGGILCDQ 274
C +C+ P +C QC PG C G+ D N CD
Sbjct: 1235 SCTDIDECEDNP----NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDL 1286
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPC--APQPCA-HG 327
+ N C GTCENT + C C G+SG C + N C C H
Sbjct: 1287 NPNIC-------LSGTCENT-KGSFICHCDMGYSGKKGKTGCTDI-NECEIGAHNCGKHA 1337
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG---PCLHGASCRDHLDGFTCECADGW 384
C+ T F C+C GW G S C A C++ + + C C +G+
Sbjct: 1338 VCT--NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 385 TGPA-CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNV 439
TG D+DECS L C N C N GGY C C G+ G+ CE ++
Sbjct: 1396 TGDGFTCTDLDECSEN------LNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACE-DI 1447
Query: 440 DDCT--GQCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVD 492
D+C+ C+ G TC +L F C C GY +G C+ DV++C P C + G CV+
Sbjct: 1448 DECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCIS-GNCVN 1504
Query: 493 LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
+Y C CP F R C + GN CY
Sbjct: 1505 TPGSYICDCPPDF---ELNPTRVGCVDTRSGN---CY 1535
Score = 110 bits (264), Expect = 3e-23
Identities = 126/446 (28%), Positives = 175/446 (39%), Gaps = 87/446 (19%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW---RGELC---SQCQPYPG--CKHGYCN 255
+ CE+ C G C T G + C C G+ C +C G C++G C
Sbjct: 1893 NECERDACGNGTCRNTIGSFN----CRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI 1948
Query: 256 GS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS- 308
+ S+ C C+ + G C D+N C GTC+N Y C C G+S
Sbjct: 1949 NTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNL-DGSYRCICPPGYSL 2006
Query: 309 -GVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC-- 363
CE +D C +P CA GTCS T F C C G+ C
Sbjct: 2007 QNEKCEDIDE-CVEEPEICALGTCS--NTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYA 2063
Query: 364 -LHGASC-----RDHLDGFTCECA---DGWTGPA--CAEDVDECSGRSMTEGA---LGPC 409
G C R+H C CA +GW P C + DE + G+ +GP
Sbjct: 2064 KFEGGKCSSPKSRNHSKQECC-CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 2122
Query: 410 VNAA--------------ACNNTAGGYSCACLAGWT--GRDCETNVDDCT-GQCLHGATC 452
+A C NT G Y C C G+T G +C + D+C+ G TC
Sbjct: 2123 DSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNEC-VDTDECSVGNPCGNGTC 2181
Query: 453 IDLVDDFHCACAAGYAG---RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF---- 505
+++ F C C G+ TC D+++CA P CV+ +Y C CPVG+
Sbjct: 2182 KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLRE 2240
Query: 506 SGTNCEDDRDHC--AGSPC-GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
C+D+ D C C C Y C C PG+ QR D + C
Sbjct: 2241 DRRMCKDE-DECEEGKHDCTEKQMECKNLIGTYMCICGPGY------QRRP-DGEGC--- 2289
Query: 563 VEESE-RCAEGMCANGGTCVREEGSW 587
V+E+E + G+C N G C+ GS+
Sbjct: 2290 VDENECQTKPGICEN-GRCLNTRGSY 2314
Score = 107 bits (258), Expect = 1e-22
Identities = 94/326 (28%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCS 330
D++ C G C N + C C GF D CE +D C P
Sbjct: 1766 DIDECREIPGVCENGVCINMV-GSFRCECPVGFFYNDKLLVCEDIDE-CQNGPVCQRNAE 1823
Query: 331 LAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
T + C C G+ G C HG C D + F C C TG
Sbjct: 1824 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCLCH---TG 1879
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDDCT 443
+D C + E C N C NT G ++C C G+ DC +VD+C
Sbjct: 1880 FKTNDDQTMCL--DINECERDACGNGT-CRNTIGSFNCRCNHGFILSHNNDC-IDVDECA 1935
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTNGGECVDLL 494
G CI+ V F C C GY GRTC +D+++C PR C G C +L
Sbjct: 1936 SGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLD 1993
Query: 495 NAYRCICPVGFSGTN--CEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+YRCICP G+S N CE D D C P C G C + + C C G++ + +
Sbjct: 1994 GSYRCICPPGYSLQNEKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGR 2051
Query: 551 RAARDRKTCSVLVEESERCAEGMCAN 576
R R + E +C+ N
Sbjct: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRN 2077
Score = 98.7 bits (235), Expect = 9e-20
Identities = 130/511 (25%), Positives = 189/511 (36%), Gaps = 81/511 (15%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR--GELC---SQCQPYPGCKHGYCNG- 256
D C++P VCK G C T G C+C G+ G C +C C +G C
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYR----CECPFGYTLAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 257 -SSWDCTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
++CTC+ + G ++ +D+N C + P C NT Y C+C G+ +
Sbjct: 2185 IGGFECTCEEGFEPGPMMTCEDINECAQN-PLLCAFRCVNTY-GSYECKCPVGYVLREDR 2242
Query: 314 RV---DNPC--APQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPC 363
R+ ++ C C + C C G+ G G C
Sbjct: 2243 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2302
Query: 364 LHGASCRDHLDGFTCECADGWTG-PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
+G C + +TCEC DG+T P E +D G TE C ++ N
Sbjct: 2303 ENGR-CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 423 SCACLAG--WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G W G CE C Q G F C G T D+D+C
Sbjct: 2362 ECCCDGGRGW-GPHCEI----CPFQ---GTVA------FKKLCPHGRGFMTNGADIDECK 2407
Query: 481 P--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C NG ECV+ +Y CIC G+ +GT+C D + C +P C +
Sbjct: 2408 VIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTSCV-DLNECNQAPKPCNFICKNTEGS 2465
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN---GGTCVREEGSWRXXX 591
Y C C G+ + R+ +D C+ + C + +C N G TC G
Sbjct: 2466 YQCSCPKGYILQE-DGRSCKDLDECAT---KQHNC-QFLCVNTIGGFTCKCPPG------ 2514
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
S + G C P + C C+ G +TG+ CE
Sbjct: 2515 ----FTQHHTSCIDNNECTSDINLCGSKGIC--QNTPGSFTCECQRGFSLDQTGSSCE-D 2567
Query: 648 LDLC-GSSPCRNGGRCVGGSGWWMCECVAGW 677
+D C G+ C++G C G + C C G+
Sbjct: 2568 VDECEGNHRCQHG--CQNIIGGYRCSCPQGY 2596
Score = 98.3 bits (234), Expect = 1e-19
Identities = 115/410 (28%), Positives = 158/410 (38%), Gaps = 94/410 (22%)
Query: 205 DNCEK-PVCKEG--CHPTHGRCDRPGDCDCRPGWR----GEL--CSQCQPYPG-CKHGYC 254
D C+ PVC+ C T G CDC+PG+R G+ ++CQ P C HG C
Sbjct: 1810 DECQNGPVCQRNAECINTAGSYR----CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC 1865
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----GGTCENTAPDQYFCRCAEGF- 307
S+ C C T G + D C C+ GTC NT + CRC GF
Sbjct: 1866 IDTVGSFYCLCHT---GFKTNDDQTMCLDINECERDACGNGTCRNTI-GSFNCRCNHGFI 1921
Query: 308 --SGVDCERVDNPCAP---QPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXX 357
DC VD CA C +G C T F C C+ G+ G
Sbjct: 1922 LSHNNDCIDVDE-CASGNGNLCRNGQC--INTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
Query: 358 XASGPCLHGASCRDHLDG-FTCECADGWT--GPACAEDVDECSGRSMTEGALGPCVNAAA 414
C G +C+ +LDG + C C G++ C ED+DEC + E + C
Sbjct: 1979 LEPRKCAPG-TCQ-NLDGSYRCICPPGYSLQNEKC-EDIDEC----VEEPEI--CA-LGT 2028
Query: 415 CNNTAGGYSCACLAGW----TGRDC-ETNVDDCTGQCLHGATCIDLVDDFH----CACAA 465
C+NT G + C C G+ +GR C + + C + G C H C CA
Sbjct: 2029 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK-FEGGKCSSPKSRNHSKQECCCAL 2087
Query: 466 GYAG-----RTCSLDVDDCAPRPCTNG-------------------------GECVDLLN 495
G C + D+ + C G G+C++
Sbjct: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 2147
Query: 496 AYRCICPVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+YRC CP G+ +G C D + G+PCGNG C + C C G+
Sbjct: 2148 SYRCECPFGYTLAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGF 2196
Score = 93.9 bits (223), Expect = 3e-18
Identities = 101/375 (26%), Positives = 140/375 (37%), Gaps = 61/375 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C PGW GD + E + TH C + DC G +C CK GY G
Sbjct: 1350 CSPGWIGDGIKCTDLDECSNGTH-MCSQHADCKNTMG-----SYRCL----CKEGY-TGD 1398
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCE 313
+ CT D + C ++LN CG G C N AP Y C C GF G CE
Sbjct: 1399 GFTCT-DLDE----CSENLNLCGN-------GQCLN-APGGYRCECDMGFVPSADGKACE 1445
Query: 314 RVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGAS 368
+D P C GTC +L G F C C+ G+ G C+ G +
Sbjct: 1446 DIDECSLPNICVFGTCHNLPGL---FRCECEIGYELDRSGGNCTDVNECLDPTTCISG-N 1501
Query: 369 CRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
C + + C+C D P VD SG + AC+N G
Sbjct: 1502 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIG------- 1554
Query: 428 AGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DVDDCAPR 482
G + C ++ G ++ ++ C G R + D+D+C
Sbjct: 1555 VGVSKASCCCSLGKAWGTPCEMCPAVN-TSEYKILCPGGEGFRPNPITVILEDIDECQEL 1613
Query: 483 P-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYC 537
P GG+C++ +++C CP G+ T DD + C CG G CY +Y C
Sbjct: 1614 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT-CYNTVGNYTC 1672
Query: 538 HCAPGWT----GKNC 548
C P + G NC
Sbjct: 1673 ICPPDYMQVNGGNNC 1687
Score = 93.1 bits (221), Expect = 4e-18
Identities = 131/510 (25%), Positives = 181/510 (35%), Gaps = 80/510 (15%)
Query: 220 HGRC-DRPGD--CDCRPGW----RGEL--CSQCQPYPGCKHGYC--NGSSWDCTCDTNWG 268
+GRC PG C+C G+ RGE +C+ P C G C N S+ C C +
Sbjct: 462 NGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP-CAGGECINNQGSYTCQCRAGYQ 520
Query: 269 GILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAP 321
L +D++ C + + G C NT + C C GF G +CE +D
Sbjct: 521 STLTRTECRDIDECLQNGRICNNGRCINT-DGSFHCVCNAGFHVTRDGKNCEDMDECSIR 579
Query: 322 QPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFT 377
C +G C F C C G+ G G C++G C + +
Sbjct: 580 NMCLNGMC--INEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYR 636
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGAL--GPCVNAAACNNTAGGYSCACLAGWTGRDC 435
CEC G + RS G G C+ T CA G C
Sbjct: 637 CECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC 696
Query: 436 ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDL 493
+ C Q + A ++ C++G + D+++CA P C N G C +L
Sbjct: 697 Q----PCPAQ--NSA-------EYQALCSSGPGMTSAGSDINECALDPDICPN-GICENL 742
Query: 494 LNAYRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
Y+CIC G+ +G NC D + S C NG C + C C G+ K
Sbjct: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIYK-- 799
Query: 549 TQRAARDRKTCSVLVE-ESERCAEGMCANG-GTCVREEGSWRXXXXXXXXXXXXDSXXXX 606
D KTC + E ES C G+C N G+ + E S
Sbjct: 800 -----PDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCW 854
Query: 607 XXXXXXXXXXQAGGTCLP----SALPPGWA-----------CGCREGR-TGALCELSLDL 650
G L S+L W CG R G CE +D
Sbjct: 855 QTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDE 913
Query: 651 CGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
C P C+N G CV G + C+C +G T
Sbjct: 914 CEVFPGVCKN-GLCVNTRGSFKCQCPSGMT 942
Score = 91.9 bits (218), Expect = 1e-17
Identities = 106/393 (26%), Positives = 151/393 (38%), Gaps = 63/393 (16%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA--SGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C++G+ PC G C ++ +TC+C
Sbjct: 460 CQNGRC--IPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQCR 516
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGR 433
G+ T C D+DEC + G + C N C NT G + C C AG+ G+
Sbjct: 517 AGYQSTLTRTEC-RDIDEC----LQNGRI--C-NNGRCINTDGSFHCVCNAGFHVTRDGK 568
Query: 434 DCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDC-APRPCTN 486
+CE ++D+C+ CL+G CI+ F C C G+ GR C D+++C P C N
Sbjct: 569 NCE-DMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMN 625
Query: 487 GGECVDLLNAYRCIC----PVGFSGTNCEDD--RDHCAG----SPCGNGAACYTAQSDYY 536
G CV+ +YRC C VG G C D R C G C +S+
Sbjct: 626 G-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECC 684
Query: 537 CHCAPGWTGKNC----TQRAARDRKTCS------VLVEESERCA--EGMCANGGTCVREE 584
C G+ C Q +A + CS + CA +C N G C
Sbjct: 685 CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLR 743
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RT 640
G+++ G C + P + C C +G
Sbjct: 744 GTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNT--PGSFVCTCPKGFIYKPD 801
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCEC 673
CE +D C SSPC N G C G ++CEC
Sbjct: 802 LKTCE-DIDECESSPCIN-GVCKNSPGSFICEC 832
Score = 87.8 bits (208), Expect = 2e-16
Identities = 95/343 (27%), Positives = 126/343 (36%), Gaps = 66/343 (19%)
Query: 190 CTPDGDKHCLPGWQ----GDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C + +C PGW+ G+ C P+C+ C G C RP C C G C +
Sbjct: 59 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGD--GFCSRPNMCTCPSGQIAPSCGS-RS 115
Query: 246 YPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C NG S C C + G C Q + G C +GG C AP++ C
Sbjct: 116 IQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG----CLNGGRC--VAPNR--CA 167
Query: 303 CAEGFSGVDCER--VDNPC----APQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
C GF+G CER PC + Q C + T + T R WG
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWG--------- 218
Query: 357 XXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
PC + A GF G AC +DVDEC + G C C
Sbjct: 219 ----HPCEMCPAQPHPCRRGFIPNIRTG----AC-QDVDEC------QAIPGLC-QGGNC 262
Query: 416 NNTAGGYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA 468
NT G + C C AG + CE ++D+C+ G C G C + V + C C G+
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGIC-EGGECTNTVSSYFCKCPPGFY 320
Query: 469 GRTCSLDVDDCAPRPC----TNG---GECVDLLNAYRCICPVG 504
D P C TNG + + +C C G
Sbjct: 321 TSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 83.4 bits (197), Expect = 4e-15
Identities = 73/265 (27%), Positives = 100/265 (37%), Gaps = 27/265 (10%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS--GVDCERVDNPCAPQPCAHGTCSLA 332
D++ C + C+HG C NT Y C C G++ G +C D PC +GTC
Sbjct: 2127 DMDECKEPDVCKHG-QCINT-DGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCK-- 2182
Query: 333 GTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACA 390
GF CTC+ G+ G A P L C + + C+C G+
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGY---VLR 2239
Query: 391 EDVDECSGRSMTEGALGPCV-NAAACNNTAGGYSCACLAGWTGR-DCETNVD--DC---T 443
ED C E C C N G Y C C G+ R D E VD +C
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 444 GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPV 503
G C +G C++ + C C G+ T S + D+C G C + +C +
Sbjct: 2300 GICENG-RCLNTRGSYTCECNDGF---TASPNQDECLD---NREGYC--FTEVLQNMCQI 2350
Query: 504 GFSGTNCEDDRDHCAGSPCGNGAAC 528
G S N + C G G C
Sbjct: 2351 GSSNRNPVTKSECCCDGGRGWGPHC 2375
Score = 82.2 bits (194), Expect = 8e-15
Identities = 99/365 (27%), Positives = 135/365 (36%), Gaps = 74/365 (20%)
Query: 231 CRPGWR----GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNYCGTHEPC 285
C PGW+ G C C G+C+ + CTC + C + + +C C
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNM-CTCPSGQIAPSCGSRSIQHCNIR--C 123
Query: 286 QHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
+GG+C + C C +G+ G C + P C +G +A C C G
Sbjct: 124 MNGGSCSDD-----HCLCQKGYIGTHCGQ---PVCESGCLNGGRCVAPNR----CACTYG 171
Query: 346 WGGXXXXXXXXXXASGPC---LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR--S 400
+ G +GPC + C+ L G C T C V G
Sbjct: 172 FTGPQCERDYR---TGPCFTVISNQMCQGQLSGIVC------TKQLCCATVGRAWGHPCE 222
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVD 457
M PC N G AC +VD+C G C G CI+ V
Sbjct: 223 MCPAQPHPCRRGFIPNIRTG----AC----------QDVDECQAIPGLC-QGGNCINTVG 267
Query: 458 DFHCACAAGY----AGRTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGT 508
F C C AG+ + C D+D+C+ P GGEC + +++Y C CP GF GT
Sbjct: 268 SFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 509 NCEDDR-DHC----AGSPCGNGAACYTAQSDYYC---HC-APGWT--GKNCTQRAARD-R 556
C D R +C C N + C C +PG T + C RA D
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFN 386
Query: 557 KTCSV 561
K CSV
Sbjct: 387 KLCSV 391
Score = 79.8 bits (188), Expect = 4e-14
Identities = 102/361 (28%), Positives = 136/361 (37%), Gaps = 70/361 (19%)
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQ--DLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C++G C S+ C C+ + L + D++ C + PC GG C N Y C+C
Sbjct: 460 CQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKN-PCA-GGECINNQ-GSYTCQCR 516
Query: 305 EGFSGV----DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXX 354
G+ +C +D C C +G C T F C C+ G+ G
Sbjct: 517 AGYQSTLTRTECRDIDE-CLQNGRICNNGRC--INTDGSFHCVCNAGFHVTRDGKNCEDM 573
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCV 410
CL+G C + F C C G+ G C +D++EC G C+
Sbjct: 574 DECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYC-KDINECE-------TPGICM 624
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDC-ETNV-DDCTGQCLHGATCIDL---VDDFHC 461
N C NT G Y C C G GR C +T++ C G G L V C
Sbjct: 625 NGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
Query: 462 ACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
CA+ T + C P P N E Y+ +C G T+ D + CA P
Sbjct: 684 CCAS-----TEYAFGEPCQPCPAQNSAE-------YQALCSSGPGMTSAGSDINECALDP 731
Query: 522 --CGNGAACYTAQSDYYCHCAPGW----TGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C NG C + Y C C G+ TGKNC D C V S C G C
Sbjct: 732 DICPNG-ICENLRGTYKCICNSGYEVDSTGKNCV-----DINEC---VLNSLLCDNGQCR 782
Query: 576 N 576
N
Sbjct: 783 N 783
Score = 77.4 bits (182), Expect = 2e-13
Identities = 111/474 (23%), Positives = 165/474 (34%), Gaps = 73/474 (15%)
Query: 237 GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
G C+ CQ P C GY C +D++ C G C NT
Sbjct: 884 GSPCTLCQVDPICGKGYSRIKGTQC------------EDIDECEVFPGVCKNGLCVNTR- 930
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPC------AHGTCSLAGTTRGFTCTCDRGWGGXX 350
+ C+C G + R+ + C T +AG R C C G
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGT 990
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
+ P R GF + + G +D++EC +
Sbjct: 991 EECEECPMRNTPEYEELCPRG--PGFATK--EITNGKPFFKDINECK-------MIPSLC 1039
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCAC 463
C NT G + C C +G+ R+C T++D+C C G C++ DF C C
Sbjct: 1040 THGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRG-QCVNTPGDFECKC 1097
Query: 464 AAGYAG-----RTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFS---GTNCEDDR 514
GY + C +D+D+C P GG C + +YRC CP G + D
Sbjct: 1098 DEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1156
Query: 515 DHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
+ C S C NG C Y C C PG+ + DR C V ++E G
Sbjct: 1157 NECELSAHLCPNG-RCVNLIGKYQCACNPGY-------HSTPDRLFC-VDIDECS-IMNG 1206
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA 632
C C EGS+ GG C + +P +
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1262
Query: 633 CGCREGRTGA----LCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTGE 680
C C +G + C + ++ C +P C + G C G ++C C G++G+
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGK 1314
Score = 65.7 bits (153), Expect = 8e-10
Identities = 61/226 (26%), Positives = 89/226 (39%), Gaps = 36/226 (15%)
Query: 474 LDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCAGSP-CGNGA 526
+D+D+C P C NG C++++ ++RC CPVGF + CE D D C P C A
Sbjct: 1765 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNA 1822
Query: 527 ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGS 586
C Y C C PG+ + Q DR C + +C++ G C+ GS
Sbjct: 1823 ECINTAGSYRCDCKPGYRFTSTGQ--CNDRNECQEI--------PNICSH-GQCIDTVGS 1871
Query: 587 WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG---RTGAL 643
+ D GTC + + C C G
Sbjct: 1872 F--YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTI--GSFNCRCNHGFILSHNND 1927
Query: 644 CELSLDLCGS---SPCRNGGRCVGGSGWWMCECVAGW----TGETC 682
C + +D C S + CRN G+C+ G + C+C G+ G TC
Sbjct: 1928 C-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTC 1971
Score = 56.4 bits (130), Expect = 5e-07
Identities = 50/199 (25%), Positives = 67/199 (33%), Gaps = 22/199 (11%)
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCED--DRDHCAGSPCGNGAACYTAQSDYYCHCAP 541
C NG C+ +YRC C GF + D D C +PC G C Q Y C C
Sbjct: 460 CQNG-RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRA 517
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD 601
G+ T+ RD C G N G C+ +GS+ D
Sbjct: 518 GYQS-TLTRTECRDIDEC---------LQNGRICNNGRCINTDGSFHCVCNAGFHVTR-D 566
Query: 602 SXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELSLDLCGSSPCR 657
G C+ + C C+ G G C+ ++ C +
Sbjct: 567 GKNCEDMDECSIRNMCLNGMCINE--DGSFKCICKPGFQLASDGRYCK-DINECETPGIC 623
Query: 658 NGGRCVGGSGWWMCECVAG 676
GRCV G + CEC G
Sbjct: 624 MNGRCVNTDGSYRCECFPG 642
Score = 43.2 bits (97), Expect = 0.005
Identities = 50/187 (26%), Positives = 66/187 (35%), Gaps = 19/187 (10%)
Query: 499 CICPVGFSGTNCEDDR-DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C CP G +C HC C NG +C SD +C C G+ G +C Q
Sbjct: 100 CTCPSGQIAPSCGSRSIQHC-NIRCMNGGSC----SDDHCLCQKGYIGTHCGQPVCESGC 154
Query: 558 TCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD-SXXXXXXXXXXXXXX 616
RCA G C R+ + S
Sbjct: 155 LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVG 214
Query: 617 QAGGTCLPSALPPGWACGCREG-----RTGALCELSLDLCGSSP--CRNGGRCVGGSGWW 669
+A G P + P CR G RTGA C+ +D C + P C+ GG C+ G +
Sbjct: 215 RAWGH--PCEMCPAQPHPCRRGFIPNIRTGA-CQ-DVDECQAIPGLCQ-GGNCINTVGSF 269
Query: 670 MCECVAG 676
C+C AG
Sbjct: 270 ECKCPAG 276
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C++G G C +C S C NGGRCV + C C G+TG C
Sbjct: 134 CLCQKGYIGTHC--GQPVCESG-CLNGGRCVAPN---RCACTYGFTGPQC 177
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 122 bits (293), Expect = 8e-27
Identities = 107/361 (29%), Positives = 151/361 (41%), Gaps = 55/361 (15%)
Query: 229 CDCRPGWRG----ELCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWG----GILCDQD 275
C C PG++ + C+ +C G C S S++C+C + G C D
Sbjct: 1224 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-AD 1282
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-SGVDCER-VD-NPCAPQP--CAHGTCS 330
++ C + GG C N P +Y C C +GF + +D + +D N C C G C
Sbjct: 1283 IDECENNPDICDGGQCTNI-PGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1341
Query: 331 LAGTTRGFTCTCDRGWG---GXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECADGWT 385
T F C C G+ G G C ASC + F C C +GW
Sbjct: 1342 --NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 1399
Query: 386 GPAC-AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE-TNVDDCT 443
G D+DECS + C A C NT G Y CAC G+TG ++VD+C
Sbjct: 1400 GNGIKCIDLDECSNGTHQ------CSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECA 1453
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C +G C+++ + C C G+ R+C D+D+C+ + G C +L
Sbjct: 1454 ENINLCENG-QCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVSGTCNNLPGM 1511
Query: 497 YRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGW----TGKN 547
+ CIC G+ +G NC D D CA C NG C Y C+C P + TG
Sbjct: 1512 FHCICDDGYELDRTGGNC-TDIDECADPINCVNG-LCVNTPGRYECNCPPDFQLNPTGVG 1569
Query: 548 C 548
C
Sbjct: 1570 C 1570
Score = 120 bits (289), Expect = 3e-26
Identities = 135/516 (26%), Positives = 194/516 (37%), Gaps = 68/516 (13%)
Query: 196 KHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKH-- 251
+ C W D C HP G+ R C C G W G C +C P PG K
Sbjct: 1000 EQCYLKWDEDEC--------IHPVPGKF-RMDACCCAVGAAW-GTECEEC-PKPGTKEYE 1048
Query: 252 GYC-NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS-- 308
C G+ + D G +D+N C G C NT + CRC GF+
Sbjct: 1049 TLCPRGAGFANRGDVLTGRPFY-KDINECKAFPGMCTYGKCRNTI-GSFKCRCNSGFALD 1106
Query: 309 --GVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG---- 361
+C +D +P C G C T F C C G+ G
Sbjct: 1107 MEERNCTDIDECRISPDLCGSGIC--VNTPGSFECECFEGYESGFMMMKNCMDIDGCERN 1164
Query: 362 PCL-HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P L G +C + F C+C G ED + + S+++ C N C N G
Sbjct: 1165 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL---CRNGK-CVNMIG 1220
Query: 421 GYSCACLAGWTG---RDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GR 470
Y C+C G+ R T++D+C G C C + + C+C+ GYA GR
Sbjct: 1221 TYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYECSCSEGYALMPDGR 1278
Query: 471 TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSPCGNG 525
+C+ D+D+C P +GG+C ++ YRC+C GF + C D + S
Sbjct: 1279 SCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 1337
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + CHC G++ K T T V+E E A C +C+ G
Sbjct: 1338 GECENTKGSFICHCQLGYSVKKGT--------TGCTDVDECEIGAHN-CDMHASCLNIPG 1388
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
S++ C+ + P + C C EG TG
Sbjct: 1389 SFKCSCREGWIGNGIKCIDLDECSNGTHQCS-INAQCVNT--PGSYRCACSEGFTGDGFT 1445
Query: 646 LS-LDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
S +D C + C NG +C+ G + CEC G+T
Sbjct: 1446 CSDVDECAENINLCENG-QCLNVPGAYRCECEMGFT 1480
Score = 118 bits (283), Expect = 1e-25
Identities = 99/342 (28%), Positives = 143/342 (41%), Gaps = 55/342 (16%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
CD GW G C C P PG + + C G +D++ C
Sbjct: 2411 CDGGRGW-GHQCELC-PLPGT-------AQYKKICPHGPGYTTDGRDIDECKVMPNLCTN 2461
Query: 289 GTCENTAPDQYFCRCAEGF----SGVDCERVDNPC-APQPCAHGTCSLAGTTRGFTCTCD 343
G C NT + C C G+ SG C +D +P+PC + C T + C+C
Sbjct: 2462 GQCINTM-GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICK--NTEGSYQCSCP 2517
Query: 344 RGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDVDEC 396
RG+ G C C + L GFTC+C G+T AC ++ +EC
Sbjct: 2518 RGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPGFTQHHTACIDN-NEC 2574
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTG--QCLHGA 450
+ + G G C NT G +SC C G+ TG +CE +VD+C G +C HG
Sbjct: 2575 GSQPLLCGGKG------ICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG- 2626
Query: 451 TCIDLVDDFHCACAAGYAGR---TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS- 506
C +++ + C C GY +D ++C+ C + L +Y+C CP GFS
Sbjct: 2627 -CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSF 2685
Query: 507 ---GTNCEDDRDHCAGS--PCGNGAACYTAQSDYYCHCAPGW 543
+ C D + C+ S PC G C + Y C C PG+
Sbjct: 2686 DQFSSACHDVNE-CSSSKNPCNYG--CSNTEGGYLCGCPPGY 2724
Score = 116 bits (280), Expect = 3e-25
Identities = 131/506 (25%), Positives = 199/506 (39%), Gaps = 83/506 (16%)
Query: 219 THGRCDRP-GD--CDCRPGWRGEL----CS---QCQPYPG-CKHGYCNGS--SWDCTCDT 265
T+G+C G C C G+ ++ C+ +C+ P C G C + S++C C
Sbjct: 1084 TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFE 1143
Query: 266 NW-GGILCDQ---DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDN 317
+ G + + D++ C + GGTC NT + C C G S DC + N
Sbjct: 1144 GYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTE-GSFQCDCPLGHELSPSREDCVDI-N 1201
Query: 318 PCAPQP--CAHGTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGA---SCRD 371
C+ C +G C ++ GT + C+C+ G+ ++G C +
Sbjct: 1202 ECSLSDNLCRNGKCVNMIGT---YQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTN 1258
Query: 372 HLDGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
+ C C++G+ G +CA D+DEC + C N G Y C C
Sbjct: 1259 SEGSYECSCSEGYALMPDGRSCA-DIDECENNP-------DICDGGQCTNIPGEYRCLCY 1310
Query: 428 AGW-TGRDCETNVD--DC---TGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDD 478
G+ D +T +D +C + C+ G C + F C C GY+ G T DVD+
Sbjct: 1311 DGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDE 1369
Query: 479 C--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSP--CGNGAACYTAQS 533
C C C+++ +++C C G+ G + D D C+ C A C
Sbjct: 1370 CEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1429
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE--GMCANGGTCVREEGSWRXXX 591
Y C C+ G+TG D TCS + + CAE +C N G C+ G++R
Sbjct: 1430 SYRCACSEGFTG---------DGFTCS----DVDECAENINLCEN-GQCLNVPGAYR-CE 1474
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
DS GTC + LP + C C +G RTG C
Sbjct: 1475 CEMGFTPASDSRSCQDIDECSFQNICVSGTC--NNLPGMFHCICDDGYELDRTGGNC-TD 1531
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC 673
+D C G CV G + C C
Sbjct: 1532 IDECADPINCVNGLCVNTPGRYECNC 1557
Score = 103 bits (246), Expect = 4e-21
Identities = 101/361 (27%), Positives = 141/361 (39%), Gaps = 47/361 (13%)
Query: 242 QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCD-----QDLNYCGTHEPCQHGGTCENTA 295
+CQ PG C+ G C + C+ G L + +D++ C H GTC NT
Sbjct: 1652 ECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL 1711
Query: 296 PDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCS--LAGTTRGFTCTCDRGWGGX 349
+ Y C C + G +C + + TC L C C G
Sbjct: 1712 GN-YTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKA 1770
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
G C ++ GFT D TG A D+DEC + G C
Sbjct: 1771 GNKPCEPCPTPGTADFKTIC-GNIPGFTF---DIHTGKAV--DIDEC------KEIPGIC 1818
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
N C N G + C C G++ D CE ++D+C+ C A CI+ + C
Sbjct: 1819 ANGV-CINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCE 1876
Query: 463 CAAGY--AGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DRD 515
CAAG+ + +D ++C P C++G CVDL +Y+CIC GF + + D D
Sbjct: 1877 CAAGFKLSPNGACVDRNECLEIPNVCSHG-LCVDLQGSYQCICHNGFKASQDQTMCMDVD 1935
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C PCGNG C Y C C PG+ + D CS + C G C
Sbjct: 1936 ECERHPCGNG-TCKNTVGSYNCLCYPGF--ELTHNNDCLDIDECSSFF--GQVCRNGRCF 1990
Query: 576 N 576
N
Sbjct: 1991 N 1991
Score = 101 bits (241), Expect = 2e-20
Identities = 113/440 (25%), Positives = 162/440 (36%), Gaps = 60/440 (13%)
Query: 164 LCQPNY-YNT--TCTTFCRPRDDKF-GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPT 219
+C P YNT T C P + G ++C C + G CE + + T
Sbjct: 1701 VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENEL---PFNVT 1757
Query: 220 HGRCDRPGDCDCRPGWRGEL-CSQCQPYPGCKH--GYCNGSSWDCTCDTNWGGILCDQDL 276
C C G G C C P PG C G+ T D + G + D+
Sbjct: 1758 KRMCC----CTYNVGKAGNKPCEPC-PTPGTADFKTIC-GNIPGFTFDIHTGKAV---DI 1808
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCSLA 332
+ C G C N + C C GFS D CE +D
Sbjct: 1809 DECKEIPGICANGVCINQI-GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1867
Query: 333 GTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP- 387
+ + C C G+ G C HG C D + C C +G+
Sbjct: 1868 NSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCICHNGFKASQ 1926
Query: 388 --ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDDC 442
DVDEC PC N C NT G Y+C C G+ DC ++D+C
Sbjct: 1927 DQTMCMDVDECERH--------PCGNGT-CKNTVGSYNCLCYPGFELTHNNDC-LDIDEC 1976
Query: 443 T---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCT-NGGECVDLL 494
+ GQ C + + F C C GY G+ C +D ++C P + + G C +L
Sbjct: 1977 SSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLE 2035
Query: 495 NAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
++RCICP G+ NC D + C P C G +C + C C PG+ + +
Sbjct: 2036 GSFRCICPPGYEVKSENCIDINE-CDEDPNICLFG-SCTNTPGGFQCLCPPGFVLSDNGR 2093
Query: 551 RAARDRKTCSVLVEESERCA 570
R R++ E+ +C+
Sbjct: 2094 RCFDTRQSFCFTNFENGKCS 2113
Score = 97.9 bits (233), Expect = 2e-19
Identities = 114/474 (24%), Positives = 179/474 (37%), Gaps = 64/474 (13%)
Query: 241 SQCQPYPG-CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGT--HEPCQ---HGGTCE 292
++C+ +PG C +G C S S+ C C G+ D C E C C
Sbjct: 956 NECEVFPGVCPNGRCVNSKGSFHCECPE---GLTLDGTGRVCLDIRMEQCYLKWDEDECI 1012
Query: 293 NTAPDQY---FCRCAEGFS-GVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
+ P ++ C CA G + G +CE P+P +L GF D G
Sbjct: 1013 HPVPGKFRMDACCCAVGAAWGTECEE-----CPKPGTKEYETLCPRGAGFANRGDVLTGR 1067
Query: 349 XXXXXXXXXXA-SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG 407
A G C +G CR+ + F C C G+ A D++E + + E +
Sbjct: 1068 PFYKDINECKAFPGMCTYG-KCRNTIGSFKCRCNSGF-----ALDMEERNCTDIDECRIS 1121
Query: 408 PCV-NAAACNNTAGGYSCACLAGWTG-----RDCETNVDDCTGQCL--HGATCIDLVDDF 459
P + + C NT G + C C G+ ++C ++D C L G TC++ F
Sbjct: 1122 PDLCGSGICVNTPGSFECECFEGYESGFMMMKNC-MDIDGCERNPLLCRGGTCVNTEGSF 1180
Query: 460 HCACAAGYA---GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT----NC 510
C C G+ R +D+++C+ C NG +CV+++ Y+C C G+ T C
Sbjct: 1181 QCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATPDRQGC 1239
Query: 511 EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
D D C G C ++ Y C C+ G+ D ++C+ ++E E
Sbjct: 1240 -TDIDECMIMNGGCDTQCTNSEGSYECSCSEGYA-------LMPDGRSCAD-IDECENNP 1290
Query: 571 EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPG 630
+ +C +GG C G +R G C
Sbjct: 1291 D-IC-DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGEC--ENTKGS 1346
Query: 631 WACGCREG---RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTG 679
+ C C+ G + G +D C G+ C C+ G + C C GW G
Sbjct: 1347 FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG 1400
Score = 95.5 bits (227), Expect = 8e-19
Identities = 112/396 (28%), Positives = 156/396 (39%), Gaps = 63/396 (15%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECA 381
C +G C T + C C+ G+ S PC +G C + + C+C
Sbjct: 504 CLNGRC--IPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNG-DCVNTPGSYYCKCH 560
Query: 382 DGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GR 433
G+ T AC D+DEC + G L C N C N+ G + C C AG+ G+
Sbjct: 561 AGFQRTPTKQACI-DIDEC----IQNGVL--CKNGR-CVNSDGSFQCICNAGFELTTDGK 612
Query: 434 DCETNVDDCT--GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDC-APRPCTN 486
+C + D+CT CL+G CI+ F C C G+ GR C+ DVD+C P C N
Sbjct: 613 NCVDH-DECTTTNMCLNGM-CINEDGSFKCICKPGFVLAPNGRYCT-DVDECQTPGICMN 669
Query: 487 GGECVDLLNAYRCICP----VGFSGTNCEDD--RDHCAG----SPCGNGAACYTAQSDYY 536
G C++ ++RC CP VG G C D R C G C +S+
Sbjct: 670 G-HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECC 728
Query: 537 CHCAPGWTGKNC----TQRAARDRKTCS----VLVE--ESERCA--EGMCANGGTCVREE 584
C G+ C + +A CS + V+ + CA +CAN G C
Sbjct: 729 CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICAN-GICENLR 787
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG---RTG 641
GS+R G C + P ++C C G RT
Sbjct: 788 GSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT--PGSYSCTCPPGYVFRTE 845
Query: 642 A-LCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAG 676
CE ++ C S+PC NG C G + CEC G
Sbjct: 846 TETCE-DINECESNPCVNGA-CRNNLGSFNCECSPG 879
Score = 95.5 bits (227), Expect = 8e-19
Identities = 72/224 (32%), Positives = 102/224 (45%), Gaps = 40/224 (17%)
Query: 317 NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCR 370
N C P C++G C T F C C G+ G PC +G +C
Sbjct: 2172 NECLESPGICSNGQC--INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG-TCT 2228
Query: 371 DHLDGFTCECADGWT-GPAC-AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
+ + F C C +G+ GP ED++EC A P + A C NT G Y C C
Sbjct: 2229 NVIGSFECNCNEGFEPGPMMNCEDINEC--------AQNPLLCALRCMNTFGSYECTCPI 2280
Query: 429 GWTGRDCET---NVDDCTGQCLH-----GATCIDLVDDFHCACAAGYA----GRTCSLDV 476
G+ R+ + ++D+C + LH G C +L+ F C C G A G C +D
Sbjct: 2281 GYALREDQKMCKDLDECA-EGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDE 2338
Query: 477 DDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
++C +P C NG CV+++ +YRC C GF SGT C D+R
Sbjct: 2339 NECRTKPGICENG-RCVNIIGSYRCECNEGFQSSSSGTECLDNR 2381
Score = 92.7 bits (220), Expect = 6e-18
Identities = 98/396 (24%), Positives = 151/396 (38%), Gaps = 61/396 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GPCLHGAS-CRDHLDGF 376
P C +G C T F C C+ G+ P L G+ C + F
Sbjct: 1080 PGMCTYGKCR--NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 1137
Query: 377 TCECADGWTGPAC----AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW-- 430
CEC +G+ D+D C + C C NT G + C C G
Sbjct: 1138 ECECFEGYESGFMMMKNCMDIDGCERNPLL------C-RGGTCVNTEGSFQCDCPLGHEL 1190
Query: 431 --TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG---RTCSLDVDDCAPR 482
+ DC ++++C+ C +G C++++ + C+C GY R D+D+C
Sbjct: 1191 SPSREDC-VDINECSLSDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECM-- 1246
Query: 483 PCTNGG---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSP--CGNGAACYTAQS 533
NGG +C + +Y C C G++ G +C D D C +P C +G C
Sbjct: 1247 -IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI-DECENNPDIC-DGGQCTNIPG 1303
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+Y C C G+ A+ D KTC ++ +E G C +GS+
Sbjct: 1304 EYRCLCYDGFM-------ASMDMKTC---IDVNECDLNSNICMFGECENTKGSFICHCQL 1353
Query: 594 XXXXXXXDSXXXXXXXXXXXXXX-QAGGTCLPSALPPGWACGCREGRTG-ALCELSLDLC 651
+ +CL +P + C CREG G + + LD C
Sbjct: 1354 GYSVKKGTTGCTDVDECEIGAHNCDMHASCLN--IPGSFKCSCREGWIGNGIKCIDLDEC 1411
Query: 652 --GSSPCRNGGRCVGGSGWWMCECVAGWTGE--TCA 683
G+ C +CV G + C C G+TG+ TC+
Sbjct: 1412 SNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS 1447
Score = 85.8 bits (203), Expect = 7e-16
Identities = 97/336 (28%), Positives = 124/336 (36%), Gaps = 67/336 (19%)
Query: 197 HCLPGWQ----GDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHG 252
+C PGW+ G+ C P+C+ C G C RP C C G C + C
Sbjct: 96 YCCPGWKTLPGGNQCIVPICRNSCGD--GFCSRPNMCTCSSGQISSTCGS-KSIQQCSVR 152
Query: 253 YCNGSSW---DCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
NG + C C + G C Q + C CQ+GG C P C C GF+G
Sbjct: 153 CMNGGTCADDHCQCQKGYIGTYCGQPV--C--ENGCQNGGRC-IAQP----CACVYGFTG 203
Query: 310 VDCER--VDNPCAPQ---PCAHGTCSLAGTTRGFTC-TCDRGWGGXXXXXXXXXXASGPC 363
CER PC Q G + T+ C T R WG PC
Sbjct: 204 PQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWG-------------HPC 250
Query: 364 -LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
+ A + GF G AC +DVDEC + G C C NT G +
Sbjct: 251 EMCPAQPQPCRRGFIPNIRTG----AC-QDVDEC------QAIPGIC-QGGNCINTVGSF 298
Query: 423 SCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
C C AG T + CE ++D+C+ G C G C + V + C C GY T
Sbjct: 299 ECRCPAGHKQSETTQKCE-DIDECSIIPGICETG-ECSNTVGSYFCVCPRGYVTSTDGSR 356
Query: 476 VDDCAPRPCTNG---GECVDLL----NAYRCICPVG 504
D C +G G C L +C C G
Sbjct: 357 CIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 392
Score = 85.0 bits (201), Expect = 1e-15
Identities = 79/291 (27%), Positives = 115/291 (39%), Gaps = 44/291 (15%)
Query: 294 TAPDQYFCRCAEGFSGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----G 347
TA + C G++ D +D P C +G C T F C C G+ G
Sbjct: 2429 TAQYKKICPHGPGYT-TDGRDIDECKVMPNLCTNGQC--INTMGSFRCFCKVGYTTDISG 2485
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGRSMTE 403
+ PC + C++ + C C G+ G C +D+DEC +
Sbjct: 2486 TSCIDLDECSQSPKPCNY--ICKNTEGSYQCSCPRGYVLQEDGKTC-KDLDECQTKQHNC 2542
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGWTGRD--CETNVDDCTGQ---CLHGATCIDLVDD 458
L C NT GG++C C G+T C N ++C Q C C +
Sbjct: 2543 QFL--------CVNTLGGFTCKCPPGFTQHHTACIDN-NECGSQPLLCGGKGICQNTPGS 2593
Query: 459 FHCACAAGYA----GRTCSLDVDDC-APRPCTNGGECVDLLNAYRCICPVGF----SGTN 509
F C C G++ G C DVD+C C +G C ++L YRC CP G+
Sbjct: 2594 FSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQ 2650
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C D+ + + CG+ A+CY Y C C G++ + A D CS
Sbjct: 2651 CVDENECSNPNACGS-ASCYNTLGSYKCACPSGFSFDQFSS-ACHDVNECS 2699
Score = 83.4 bits (197), Expect = 4e-15
Identities = 110/389 (28%), Positives = 148/389 (38%), Gaps = 86/389 (22%)
Query: 249 CKHGYC--NGSSWDCTCDTNWGGILCDQ--DLNYCGTHEPCQHGGTCENTAPDQYFCRCA 304
C +G C SS+ C C+ + D++ C T PC +G C NT P Y+C+C
Sbjct: 504 CLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDEC-TSNPCTNGD-CVNT-PGSYYCKCH 560
Query: 305 EGFSGVDCER--VD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXX 355
GF ++ +D + C C +G C + F C C+ G+ G
Sbjct: 561 AGFQRTPTKQACIDIDECIQNGVLCKNGRC--VNSDGSFQCICNAGFELTTDGKNCVDHD 618
Query: 356 XXXASGPCLHGASCRDHLDGFTCECADGW----TGPACAEDVDECSGRSMTEGALGPCVN 411
+ CL+G C + F C C G+ G C DVDEC G C+N
Sbjct: 619 ECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCT-DVDECQ-------TPGICMN 669
Query: 412 AAACNNTAGGYSCAC----LAGWTGRDC-ETNV-DDCTGQCLHGATCI----DLVDDFHC 461
C N+ G + C C G GR C +T++ C G G C+ V C
Sbjct: 670 -GHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG-VCVRPFPGAVTKSEC 727
Query: 462 ACA-AGYA-GRTC------------------------SLDVDDCA--PRPCTNGGECVDL 493
CA Y G C D+++CA P C N G C +L
Sbjct: 728 CCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICAN-GICENL 786
Query: 494 LNAYRCICPVGF----SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKN 547
+YRC C G+ SG NC D D C + C NG C Y C C PG+ +
Sbjct: 787 RGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNG-LCRNTPGSYSCTCPPGYVFRT 844
Query: 548 CTQRAARDRKTCSVLVEESERCAEGMCAN 576
T+ D C ES C G C N
Sbjct: 845 ETE-TCEDINEC-----ESNPCVNGACRN 867
Score = 82.2 bits (194), Expect = 8e-15
Identities = 91/339 (26%), Positives = 124/339 (36%), Gaps = 70/339 (20%)
Query: 231 CRPGWR----GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNYCGTHEPC 285
C PGW+ G C C G+C+ + CTC + C + + C C
Sbjct: 97 CCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNM-CTCSSGQISSTCGSKSIQQCSVR--C 153
Query: 286 QHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
+GGTC A D C+C +G+ G C QP C G C C G
Sbjct: 154 MNGGTC---ADDH--CQCQKGYIGTYCG--------QPVCENGCQNGGRCIAQPCACVYG 200
Query: 346 WGGXXXXXXXXXXASGPC---LHGASCRDHLDGFTCE----CADGWTGPACAEDVDECSG 398
+ G +GPC ++ C+ L G C CA TG A + C
Sbjct: 201 FTGPQCERDYR---TGPCFTQVNNQMCQGQLTGIVCTKTLCCAT--TGRAWGHPCEMCPA 255
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDL 455
+ PC N G AC +VD+C G C G CI+
Sbjct: 256 QPQ------PCRRGFIPNIRTG----AC----------QDVDECQAIPGIC-QGGNCINT 294
Query: 456 VDDFHCACAAGY----AGRTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----S 506
V F C C AG+ + C D+D+C+ P GEC + + +Y C+CP G+
Sbjct: 295 VGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTD 353
Query: 507 GTNCEDDRDHCAGSPCGNGAACYT---AQSDYYCHCAPG 542
G+ C D R S NG + C C PG
Sbjct: 354 GSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 392
Score = 81.4 bits (192), Expect = 1e-14
Identities = 99/428 (23%), Positives = 141/428 (32%), Gaps = 57/428 (13%)
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCAPQPCAHGTC 329
+D+N C G C NT + C C G++ GV C D PC +GTC
Sbjct: 2169 EDVNECLESPGICSNGQCINT-DGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTC 2227
Query: 330 SLAGTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
+ F C C+ G+ G A P L C + + C C G+
Sbjct: 2228 T--NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGY--- 2282
Query: 388 ACAEDVDECSGRSMTEGALGPCVN-AAACNNTAGGYSCACLAGWTGR-DCETNVD--DC- 442
A ED C L C + C N G + C C G R D E VD +C
Sbjct: 2283 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 2342
Query: 443 --TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
G C +G C++++ + C C G+ + + C + + + + I
Sbjct: 2343 TKPGICENG-RCVNIIGSYRCECNEGFQSSSSGTE--------CLDNRQGLCFAEVLQTI 2393
Query: 501 CPVGFSGTNCEDDRDHCAGSPCGNGAACY------TAQSDYYCHCAPGWTGKNCTQRAAR 554
C + S N + C G G C TAQ C PG+T R
Sbjct: 2394 CQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT------TDGR 2447
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
D C V+ +C N G C+ GS+R D
Sbjct: 2448 DIDECKVM--------PNLCTN-GQCINTMGSFR---CFCKVGYTTDISGTSCIDLDECS 2495
Query: 615 XXQAGGTCLPSALPPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGWWM 670
+ + C C G G C+ LD C + CV G +
Sbjct: 2496 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFT 2554
Query: 671 CECVAGWT 678
C+C G+T
Sbjct: 2555 CKCPPGFT 2562
Score = 74.5 bits (175), Expect = 2e-12
Identities = 110/401 (27%), Positives = 147/401 (36%), Gaps = 85/401 (21%)
Query: 204 GDNC-EKPVCKEGCHPTHGRC---DRPGDCDCRPGW----RGELCS---QCQPYPGCKHG 252
G NC + C +G C D C C+PG+ G C+ +CQ C +G
Sbjct: 611 GKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNG 670
Query: 253 YCNGSSWDCTCDTNWGGILCDQDLNYC-GTH--EPCQHG---GTCENTAPDQYF---CRC 303
+C S CD G+ D C TH C G G C P C C
Sbjct: 671 HCINSEGSFRCDCP-PGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCC 729
Query: 304 AEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGP- 362
A G PC QPC A + F C G G A P
Sbjct: 730 ANPDYGFG-----EPC--QPCP------AKNSAEFHGLCSSGVGITVDGRDINECALDPD 776
Query: 363 -CLHGASCRDHLDGFTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNT 418
C +G C + + C C G+ A D+DEC + C N C NT
Sbjct: 777 ICANGI-CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLL------CDNGL-CRNT 828
Query: 419 AGGYSCACLAGWTGR-DCET--NVDDC-TGQCLHGATCIDLVDDFHCACAAG-------- 466
G YSC C G+ R + ET ++++C + C++GA C + + F+C C+ G
Sbjct: 829 PGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGL 887
Query: 467 ----YAGRTCSLDVDDCAPRPCTNG----GECVDLLNA------YRC----ICPVGFS-- 506
TC L++ D NG EC L A RC CP G +
Sbjct: 888 ICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARI 947
Query: 507 -GTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWT 544
G CED + C P C NG C ++ ++C C G T
Sbjct: 948 KGVTCEDVNE-CEVFPGVCPNG-RCVNSKGSFHCECPEGLT 986
Score = 62.1 bits (144), Expect = 1e-08
Identities = 73/290 (25%), Positives = 99/290 (34%), Gaps = 67/290 (23%)
Query: 323 PCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
P +C +R CTC G S C++G +C D C+C
Sbjct: 113 PICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQK 168
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE------ 436
G+ G C + V E C N C CAC+ G+TG CE
Sbjct: 169 GYIGTYCGQPVCE-----------NGCQNGGRCI----AQPCACVYGFTGPQCERDYRTG 213
Query: 437 ---TNVDD--CTGQCLHGATCIDLVDDFHCACAAGYA-GRTCSL---------------- 474
T V++ C GQ L G C + C G A G C +
Sbjct: 214 PCFTQVNNQMCQGQ-LTGIVCTKTL----CCATTGRAWGHPCEMCPAQPQPCRRGFIPNI 268
Query: 475 ------DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP-- 521
DVD+C P GG C++ + ++ C CP G + CE D D C+ P
Sbjct: 269 RTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGI 327
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
C G C Y+C C G+ R R + RCA+
Sbjct: 328 CETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQ 376
Score = 48.4 bits (110), Expect = 1e-04
Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 25/183 (13%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCN-GSSWDCTCDTNWGGI 270
C G H C +C +P G CQ PG C G S D T G+
Sbjct: 2557 CPPGFTQHHTACIDNNECGSQPLLCGGK-GICQNTPGSFSCECQRGFSLDAT------GL 2609
Query: 271 LCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG----FSGVDCERVDNPCAPQPCAH 326
C+ D++ C + CQHG C+N Y C C +G + C +N C+ P A
Sbjct: 2610 NCE-DVDECDGNHRCQHG--CQNIL-GGYRCGCPQGYIQHYQWNQCVD-ENECS-NPNAC 2663
Query: 327 GTCSLAGTTRGFTCTCDRG-----WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECA 381
G+ S T + C C G + + PC +G C + G+ C C
Sbjct: 2664 GSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCP 2721
Query: 382 DGW 384
G+
Sbjct: 2722 PGY 2724
Score = 46.4 bits (105), Expect = 5e-04
Identities = 60/248 (24%), Positives = 81/248 (32%), Gaps = 27/248 (10%)
Query: 193 DGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHG 252
D C G+ G C +PVC+ GC GRC C C G+ G C + + G
Sbjct: 161 DDHCQCQKGYIGTYCGQPVCENGCQ-NGGRCIAQ-PCACVYGFTGPQCER-----DYRTG 213
Query: 253 YCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----- 307
C + C GI+C + L C G CE CR GF
Sbjct: 214 PCFTQVNNQMCQGQLTGIVCTKTL--CCATTGRAWGHPCEMCPAQPQPCR--RGFIPNIR 269
Query: 308 SGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+G C+ VD P C G C T F C C G + G
Sbjct: 270 TGA-CQDVDECQAIPGICQGGNC--INTVGSFECRCPAGHKQSETTQKCEDIDECSIIPG 326
Query: 367 ----ASCRDHLDGFTCECADGW-TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
C + + + C C G+ T + +D+ +G + G C T
Sbjct: 327 ICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTK-- 384
Query: 422 YSCACLAG 429
C C G
Sbjct: 385 MQCCCEPG 392
Score = 39.1 bits (87), Expect = 0.077
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 13/64 (20%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC C C++G G C +C + C+NGGRC+ C CV G+T
Sbjct: 156 GGTCADDH------CQCQKGYIGTYC--GQPVCENG-CQNGGRCIAQP----CACVYGFT 202
Query: 679 GETC 682
G C
Sbjct: 203 GPQC 206
Score = 37.5 bits (83), Expect = 0.24
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
Query: 620 GTCLPSALPPGWACGCREG-RTGALCE-LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
G C+P+ + C C G + A + + +D C S+PC NG CV G + C+C AG+
Sbjct: 507 GRCIPTV--SSYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGF 563
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 122 bits (293), Expect = 8e-27
Identities = 130/491 (26%), Positives = 192/491 (39%), Gaps = 78/491 (15%)
Query: 242 QCQPYPG-CKHGYCNG--SSWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTA 295
+C+ PG C++G C S+ C C + +L +D++ C CQ C NTA
Sbjct: 204 ECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA 263
Query: 296 PDQYFCRCAEGFSGVDCERVD--NPC--APQPCAHGTCSLAGTTRGFTCTCDRGW--GGX 349
Y C C G+ + + N C P C+HG C T F C C G+
Sbjct: 264 -GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC--IDTVGSFYCLCHTGFKTNDD 320
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGAL 406
+CR+ + F C C G+ C DVDEC+ + G L
Sbjct: 321 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI-DVDECASGN---GNL 376
Query: 407 GPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDC---TGQCLHGATCIDLVDDF 459
C N C NT G + C C G+ GR C ++++C +C G TC +L +
Sbjct: 377 --CRN-GQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSY 431
Query: 460 HCACAAGYA--GRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCE 511
C C GY+ C D+D+C P C G C + +++C+CP GF SG C+
Sbjct: 432 RCICPPGYSLQNEKCE-DIDECVEEPEICAL-GTCSNTEGSFKCLCPEGFSLSSSGRRCQ 489
Query: 512 DDR-DHCAGSPCGNGAACYTAQSDYY----CHCA---PGWTGKNC----TQRAARDRKTC 559
D R +C G C + +S + C CA GW G C T+ R+ C
Sbjct: 490 DLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAFRQIC 546
Query: 560 ----SVLV------EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++V + + C E G C+ +GS+R +
Sbjct: 547 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECS 606
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGCREG-RTGAL--CELSLDLCGSSPCRNGGRCVGGS 666
GTC + G+ C C EG G + CE ++ C +P RCV
Sbjct: 607 VGNPC---GNGTC--KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTY 660
Query: 667 GWWMCECVAGW 677
G + C+C G+
Sbjct: 661 GSYECKCPVGY 671
Score = 108 bits (259), Expect = 1e-22
Identities = 125/446 (28%), Positives = 174/446 (39%), Gaps = 87/446 (19%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW---RGELC---SQCQPYPG--CKHGYCN 255
+ CE+ C G C T G + C C G+ C +C G C++G C
Sbjct: 328 NECERDACGNGTCRNTIGSFN----CRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI 383
Query: 256 GS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS- 308
+ S+ C C+ + G C D+N C GTC+N Y C C G+S
Sbjct: 384 NTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNL-DGSYRCICPPGYSL 441
Query: 309 -GVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC-- 363
CE +D C +P CA GTCS T F C C G+ C
Sbjct: 442 QNEKCEDIDE-CVEEPEICALGTCS--NTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYA 498
Query: 364 -LHGASC-----RDHLDGFTCECA---DGWTGPA--CAEDVDECSGRSMTEGA---LGPC 409
G C R+H C CA +GW P C + DE + G+ +GP
Sbjct: 499 KFEGGKCSSPKSRNHSKQECC-CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 557
Query: 410 VNAA--------------ACNNTAGGYSCACLAGW--TGRDCETNVDDCT-GQCLHGATC 452
+A C NT G Y C C G+ G +C + D+C+ G TC
Sbjct: 558 DSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNGTC 616
Query: 453 IDLVDDFHCACAAGYAG---RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF---- 505
+++ F C C G+ TC D+++CA P CV+ +Y C CPVG+
Sbjct: 617 KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLRE 675
Query: 506 SGTNCEDDRDHC--AGSPC-GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
C+D+ D C C C Y C C PG+ QR D + C
Sbjct: 676 DRRMCKDE-DECEEGKHDCTEKQMECKNLIGTYMCICGPGY------QRRP-DGEGC--- 724
Query: 563 VEESE-RCAEGMCANGGTCVREEGSW 587
V+E+E + G+C N G C+ GS+
Sbjct: 725 VDENECQTKPGICEN-GRCLNTRGSY 749
Score = 107 bits (258), Expect = 1e-22
Identities = 94/326 (28%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCS 330
D++ C G C N + C C GF D CE +D C P
Sbjct: 201 DIDECREIPGVCENGVCINMV-GSFRCECPVGFFYNDKLLVCEDIDE-CQNGPVCQRNAE 258
Query: 331 LAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
T + C C G+ G C HG C D + F C C TG
Sbjct: 259 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCLCH---TG 314
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDDCT 443
+D C + E C N C NT G ++C C G+ DC +VD+C
Sbjct: 315 FKTNDDQTMCL--DINECERDACGNGT-CRNTIGSFNCRCNHGFILSHNNDC-IDVDECA 370
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTNGGECVDLL 494
G CI+ V F C C GY GRTC +D+++C PR C G C +L
Sbjct: 371 SGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLD 428
Query: 495 NAYRCICPVGFSGTN--CEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+YRCICP G+S N CE D D C P C G C + + C C G++ + +
Sbjct: 429 GSYRCICPPGYSLQNEKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGR 486
Query: 551 RAARDRKTCSVLVEESERCAEGMCAN 576
R R + E +C+ N
Sbjct: 487 RCQDLRMSYCYAKFEGGKCSSPKSRN 512
Score = 98.3 bits (234), Expect = 1e-19
Identities = 115/410 (28%), Positives = 158/410 (38%), Gaps = 94/410 (22%)
Query: 205 DNCEK-PVCKEG--CHPTHGRCDRPGDCDCRPGWR----GEL--CSQCQPYPG-CKHGYC 254
D C+ PVC+ C T G CDC+PG+R G+ ++CQ P C HG C
Sbjct: 245 DECQNGPVCQRNAECINTAGSYR----CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC 300
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----GGTCENTAPDQYFCRCAEGF- 307
S+ C C T G + D C C+ GTC NT + CRC GF
Sbjct: 301 IDTVGSFYCLCHT---GFKTNDDQTMCLDINECERDACGNGTCRNTI-GSFNCRCNHGFI 356
Query: 308 --SGVDCERVDNPCAP---QPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXX 357
DC VD CA C +G C T F C C+ G+ G
Sbjct: 357 LSHNNDCIDVDE-CASGNGNLCRNGQC--INTVGSFQCQCNEGYEVAPDGRTCVDINECL 413
Query: 358 XASGPCLHGASCRDHLDG-FTCECADGWT--GPACAEDVDECSGRSMTEGALGPCVNAAA 414
C G +C+ +LDG + C C G++ C ED+DEC + E + C
Sbjct: 414 LEPRKCAPG-TCQ-NLDGSYRCICPPGYSLQNEKC-EDIDEC----VEEPEI--CA-LGT 463
Query: 415 CNNTAGGYSCACLAGW----TGRDC-ETNVDDCTGQCLHGATCIDLVDDFH----CACAA 465
C+NT G + C C G+ +GR C + + C + G C H C CA
Sbjct: 464 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK-FEGGKCSSPKSRNHSKQECCCAL 522
Query: 466 GYAG-----RTCSLDVDDCAPRPCTNG-------------------------GECVDLLN 495
G C + D+ + C G G+C++
Sbjct: 523 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 582
Query: 496 AYRCICPVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+YRC CP G+ +G C D + G+PCGNG C + C C G+
Sbjct: 583 SYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGF 631
Score = 93.1 bits (221), Expect = 4e-18
Identities = 77/254 (30%), Positives = 109/254 (42%), Gaps = 44/254 (17%)
Query: 288 GGTCE--NTAPDQYF---CRCAEGFS-GVDCERVD-NPCA-PQPCAHGTCSLAGTTRGFT 339
G CE T PD+ F C G G D VD + C P C HG C T +
Sbjct: 528 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC--INTDGSYR 585
Query: 340 CTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT-GPACA-EDVDE 395
C C G+ G PC +G +C++ + GF C C +G+ GP ED++E
Sbjct: 586 CECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCEDINE 644
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD----------CETNVDDCTGQ 445
C A P + A C NT G Y C C G+ R+ CE DCT +
Sbjct: 645 C--------AQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 696
Query: 446 CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRP--CTNGGECVDLLNAYRC 499
+ C +L+ + C C GY G C +D ++C +P C NG C++ +Y C
Sbjct: 697 QME---CKNLIGTYMCICGPGYQRRPDGEGC-VDENECQTKPGICENG-RCLNTRGSYTC 751
Query: 500 ICPVGFSGTNCEDD 513
C GF+ + +D+
Sbjct: 752 ECNDGFTASPNQDE 765
Score = 83.4 bits (197), Expect = 4e-15
Identities = 62/199 (31%), Positives = 83/199 (41%), Gaps = 29/199 (14%)
Query: 363 CLHGASCRDHLDGFTCECADGW--TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
C HG C + + CEC G+ G C D DECS + PC N C N G
Sbjct: 572 CKHG-QCINTDGSYRCECPFGYILAGNECV-DTDECSVGN-------PCGNGT-CKNVIG 621
Query: 421 GYSCACLAGWTGRDCET--NVDDCTGQCLHGA-TCIDLVDDFHCACAAGYA---GRTCSL 474
G+ C C G+ T ++++C L A C++ + C C GY R
Sbjct: 622 GFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCK 681
Query: 475 DVDDC--APRPCTNGG-ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSP--CGNG 525
D D+C CT EC +L+ Y CIC G+ G C D+ + C P C NG
Sbjct: 682 DEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENE-CQTKPGICENG 740
Query: 526 AACYTAQSDYYCHCAPGWT 544
C + Y C C G+T
Sbjct: 741 R-CLNTRGSYTCECNDGFT 758
Score = 79.4 bits (187), Expect = 6e-14
Identities = 63/216 (29%), Positives = 86/216 (39%), Gaps = 22/216 (10%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF--SGVDCERVDNPCAPQPCAHGTCSLA 332
D++ C + C+HG C NT Y C C G+ +G +C D PC +GTC
Sbjct: 562 DMDECKEPDVCKHG-QCINT-DGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCK-- 617
Query: 333 GTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACA 390
GF CTC+ G+ G A P L C + + C+C G+
Sbjct: 618 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGY---VLR 674
Query: 391 EDVDECSGRSMTEGALGPCV-NAAACNNTAGGYSCACLAGWTGR-DCETNVD--DC---T 443
ED C E C C N G Y C C G+ R D E VD +C
Sbjct: 675 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 734
Query: 444 GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C +G C++ + C C G+ T S + D+C
Sbjct: 735 GICENG-RCLNTRGSYTCECNDGF---TASPNQDEC 766
Score = 65.7 bits (153), Expect = 8e-10
Identities = 61/226 (26%), Positives = 89/226 (39%), Gaps = 36/226 (15%)
Query: 474 LDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCAGSP-CGNGA 526
+D+D+C P C NG C++++ ++RC CPVGF + CE D D C P C A
Sbjct: 200 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNA 257
Query: 527 ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGS 586
C Y C C PG+ + Q DR C + +C++ G C+ GS
Sbjct: 258 ECINTAGSYRCDCKPGYRFTSTGQ--CNDRNECQEI--------PNICSH-GQCIDTVGS 306
Query: 587 WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG---RTGAL 643
+ D GTC + + C C G
Sbjct: 307 F--YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTI--GSFNCRCNHGFILSHNND 362
Query: 644 CELSLDLCGS---SPCRNGGRCVGGSGWWMCECVAGW----TGETC 682
C + +D C S + CRN G+C+ G + C+C G+ G TC
Sbjct: 363 C-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTC 406
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 10/83 (12%)
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHC-AGSPCGNGAACY 529
D+D+C P GG+C++ +++C CP G+ T DD + C CG G CY
Sbjct: 41 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT-CY 99
Query: 530 TAQSDYYCHCAPGWT----GKNC 548
+Y C C P + G NC
Sbjct: 100 NTVGNYTCICPPDYMQVNGGNNC 122
Score = 48.0 bits (109), Expect = 2e-04
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 13/88 (14%)
Query: 438 NVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGEC 490
++D+C G C G CI+ F C C GY R C DV++C G C
Sbjct: 41 DIDECQELPGLC-QGGKCINTFGSFQCRCPTGYYLNEDTRVCD-DVNECETPGICGPGTC 98
Query: 491 VDLLNAYRCICPVGF----SGTNCEDDR 514
+ + Y CICP + G NC D R
Sbjct: 99 YNTVGNYTCICPPDYMQVNGGNNCMDMR 126
Score = 42.7 bits (96), Expect = 0.006
Identities = 60/245 (24%), Positives = 86/245 (35%), Gaps = 44/245 (17%)
Query: 361 GPCLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNN 417
G C G C + F C C G+ +DV+EC T G GP C N
Sbjct: 50 GLC-QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE----TPGICGP----GTCYN 100
Query: 418 TAGGYSCACLAGWT----GRDC-ETNVDDC------TGQCLHGATCIDLVDDFHCACAAG 466
T G Y+C C + G +C + C Q G ++ C C+
Sbjct: 101 TVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKM-CCCSYN 159
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP--CGN 524
GR + + C P P T+ E L + R + T D D C P C N
Sbjct: 160 -IGRAWNKPCEQC-PIPSTD--EFATLCGSQRPGFVIDIY-TGLPVDIDECREIPGVCEN 214
Query: 525 GAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVRE 583
G C + C C G+ D+ ++ E+ + C G +C C+
Sbjct: 215 G-VCINMVGSFRCECPVGF--------FYNDK---LLVCEDIDECQNGPVCQRNAECINT 262
Query: 584 EGSWR 588
GS+R
Sbjct: 263 AGSYR 267
Score = 36.3 bits (80), Expect = 0.54
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 13/82 (15%)
Query: 391 EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTGQC 446
ED+DEC + G C C NT G + C C G+ R C+ +V++C
Sbjct: 40 EDIDEC------QELPGLC-QGGKCINTFGSFQCRCPTGYYLNEDTRVCD-DVNECETPG 91
Query: 447 LHG-ATCIDLVDDFHCACAAGY 467
+ G TC + V ++ C C Y
Sbjct: 92 ICGPGTCYNTVGNYTCICPPDY 113
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 122 bits (293), Expect = 8e-27
Identities = 130/491 (26%), Positives = 192/491 (39%), Gaps = 78/491 (15%)
Query: 242 QCQPYPG-CKHGYCNG--SSWDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTA 295
+C+ PG C++G C S+ C C + +L +D++ C CQ C NTA
Sbjct: 1769 ECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA 1828
Query: 296 PDQYFCRCAEGFSGVDCERVD--NPC--APQPCAHGTCSLAGTTRGFTCTCDRGW--GGX 349
Y C C G+ + + N C P C+HG C T F C C G+
Sbjct: 1829 -GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC--IDTVGSFYCLCHTGFKTNDD 1885
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGAL 406
+CR+ + F C C G+ C DVDEC+ + G L
Sbjct: 1886 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI-DVDECASGN---GNL 1941
Query: 407 GPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDC---TGQCLHGATCIDLVDDF 459
C N C NT G + C C G+ GR C ++++C +C G TC +L +
Sbjct: 1942 --CRN-GQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSY 1996
Query: 460 HCACAAGYA--GRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCE 511
C C GY+ C D+D+C P C G C + +++C+CP GF SG C+
Sbjct: 1997 RCICPPGYSLQNEKCE-DIDECVEEPEICAL-GTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 512 DDR-DHCAGSPCGNGAACYTAQSDYY----CHCA---PGWTGKNC----TQRAARDRKTC 559
D R +C G C + +S + C CA GW G C T+ R+ C
Sbjct: 2055 DLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAFRQIC 2111
Query: 560 ----SVLV------EESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXX 609
++V + + C E G C+ +GS+R +
Sbjct: 2112 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECS 2171
Query: 610 XXXXXXXQAGGTCLPSALPPGWACGCREG-RTGAL--CELSLDLCGSSPCRNGGRCVGGS 666
GTC + G+ C C EG G + CE ++ C +P RCV
Sbjct: 2172 VGNPC---GNGTC--KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTY 2225
Query: 667 GWWMCECVAGW 677
G + C+C G+
Sbjct: 2226 GSYECKCPVGY 2236
Score = 114 bits (275), Expect = 1e-24
Identities = 108/396 (27%), Positives = 159/396 (40%), Gaps = 54/396 (13%)
Query: 205 DNCEKP--VCKEG-CHPTHG--RCDRPGDCDCRPGWRGEL-CSQCQPYPG-CKHGYCNG- 256
D C++ +C+ G CH T G RC+ P P + ++C+ C +G C
Sbjct: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
Query: 257 -SSWDCTCDTNWGGILCDQDLNYCGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGV- 310
+ C C+ G D +C + C G CE + Y C C GF+ +
Sbjct: 1175 IGKYQCACNP---GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 311 ---DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP 362
C +D C P C G C+ + C C G+ P
Sbjct: 1232 DQRSCTDIDE-CEDNPNICDGGQCT--NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNP 1288
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
CL G +C + F C C G++G + C+ + E C A C NTAG
Sbjct: 1289 NICLSG-TCENTKGSFICHCDMGYSGK---KGKTGCTDINECEIGAHNCGKHAVCTNTAG 1344
Query: 421 GYSCACLAGWTGRDCE-TNVDDC---TGQCLHGATCIDLVDDFHCACAAGYAGR--TCSL 474
+ C+C GW G + T++D+C T C A C + + + C C GY G TC+
Sbjct: 1345 SFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCT- 1403
Query: 475 DVDDCAP--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAAC 528
D+D+C+ C N G+C++ YRC C +GF G CED + + C G C
Sbjct: 1404 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFG-TC 1461
Query: 529 YTAQSDYYCHCAPGW----TGKNCTQ-RAARDRKTC 559
+ + C C G+ +G NCT D TC
Sbjct: 1462 HNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTC 1497
Score = 113 bits (271), Expect = 4e-24
Identities = 92/341 (26%), Positives = 143/341 (41%), Gaps = 53/341 (15%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQH 287
CD GW G C C P+ G ++ C G + D++ C H+ C++
Sbjct: 2365 CDGGRGW-GPHCEIC-PFQGTV-------AFKKLCPHGRGFMTNGADIDECKVIHDVCRN 2415
Query: 288 GGTCENTAPDQYFCRCAEGFS----GVDCERVDNPC--APQPCAHGTCSLAGTTRGFTCT 341
G C N Y C C G++ G C + N C AP+PC + C T + C+
Sbjct: 2416 G-ECVNDR-GSYHCICKTGYTPDITGTSCVDL-NECNQAPKPC-NFICK--NTEGSYQCS 2469
Query: 342 CDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDEC 396
C +G+ G C C + + GFTC+C G+T + C
Sbjct: 2470 CPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPGFT-----QHHTSC 2522
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTG--QCLHGA 450
+ + C + C NT G ++C C G+ TG CE +VD+C G +C HG
Sbjct: 2523 IDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG- 2580
Query: 451 TCIDLVDDFHCACAAGYAGR---TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS- 506
C +++ + C+C GY +D ++C G C + L +Y+C+CP GF
Sbjct: 2581 -CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQY 2639
Query: 507 ---GTNCEDDRD-HCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C+D + A +PC G++ + Y C C PG+
Sbjct: 2640 EQFSGGCQDINECGSAQAPCSYGSS--NTEGGYLCGCPPGY 2678
Score = 111 bits (268), Expect = 9e-24
Identities = 129/513 (25%), Positives = 189/513 (36%), Gaps = 68/513 (13%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQC--QPYPGCKHGYCN 255
C ++ + C P+ G H C C W E C +C + P +
Sbjct: 958 CFLRYEDEECTLPIA--GRHRMDACC-----CSVGAAWGTEECEECPMRNTPEYEELCPR 1010
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GV 310
G + TN G +D+N C C HG C NT + CRC GF+
Sbjct: 1011 GPGFATKEITN--GKPFFKDINECKMIPSLCTHG-KCRNTI-GSFKCRCDSGFALDSEER 1066
Query: 311 DCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----GPCL- 364
+C +D +P C G C T F C CD G+ P L
Sbjct: 1067 NCTDIDECRISPDLCGRGQC--VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 1124
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C + + CEC G + ++ C + E + C N C N G Y C
Sbjct: 1125 RGGVCHNTEGSYRCECP---PGHQLSPNISACIDINECELSAHLCPN-GRCVNLIGKYQC 1180
Query: 425 ACLAGW---TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSL 474
AC G+ R ++D+C+ G C C + + C+C G+A R+C+
Sbjct: 1181 ACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCT- 1237
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAA 527
D+D+C P +GG+C ++ YRC+C GF + C D + C +P C +G
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE-CDLNPNICLSG-T 1295
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + CHC G++GK KT + E E A C C GS+
Sbjct: 1296 CENTKGSFICHCDMGYSGKK--------GKTGCTDINECEIGAHN-CGKHAVCTNTAGSF 1346
Query: 588 RXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTG-ALCEL 646
+ Q C + + C C+EG TG
Sbjct: 1347 KCSCSPGWIGDGIKCTDLDECSNGTHMCSQ-HADCKNTM--GSYRCLCKEGYTGDGFTCT 1403
Query: 647 SLDLCGS--SPCRNGGRCVGGSGWWMCECVAGW 677
LD C + C N G+C+ G + CEC G+
Sbjct: 1404 DLDECSENLNLCGN-GQCLNAPGGYRCECDMGF 1435
Score = 111 bits (266), Expect = 2e-23
Identities = 114/397 (28%), Positives = 153/397 (38%), Gaps = 75/397 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHG 221
C P Y++T FC D+ + C + C C C+ G P
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECSIMNGGC----ETFCTNSEGSYECS---CQPGFALMPDQR 1234
Query: 222 RCDRPGDCDCRPGWRGELC--SQCQPYPG-----CKHGYCNGSSWDCTCDTNWGGILCDQ 274
C +C+ P +C QC PG C G+ D N CD
Sbjct: 1235 SCTDIDECEDNP----NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDL 1286
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPC--APQPCA-HG 327
+ N C GTCENT + C C G+SG C + N C C H
Sbjct: 1287 NPNIC-------LSGTCENT-KGSFICHCDMGYSGKKGKTGCTDI-NECEIGAHNCGKHA 1337
Query: 328 TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG---PCLHGASCRDHLDGFTCECADGW 384
C+ T F C+C GW G S C A C++ + + C C +G+
Sbjct: 1338 VCT--NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
Query: 385 TGPA-CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNV 439
TG D+DECS L C N C N GGY C C G+ G+ CE ++
Sbjct: 1396 TGDGFTCTDLDECSEN------LNLCGN-GQCLNAPGGYRCECDMGFVPSADGKACE-DI 1447
Query: 440 DDCT--GQCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDCA-PRPCTNGGECVD 492
D+C+ C+ G TC +L F C C GY +G C+ DV++C P C + G CV+
Sbjct: 1448 DECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCIS-GNCVN 1504
Query: 493 LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACY 529
+Y C CP F R C + GN CY
Sbjct: 1505 TPGSYICDCPPDF---ELNPTRVGCVDTRSGN---CY 1535
Score = 108 bits (259), Expect = 1e-22
Identities = 125/446 (28%), Positives = 174/446 (39%), Gaps = 87/446 (19%)
Query: 205 DNCEKPVCKEG-CHPTHGRCDRPGDCDCRPGW---RGELC---SQCQPYPG--CKHGYCN 255
+ CE+ C G C T G + C C G+ C +C G C++G C
Sbjct: 1893 NECERDACGNGTCRNTIGSFN----CRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI 1948
Query: 256 GS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS- 308
+ S+ C C+ + G C D+N C GTC+N Y C C G+S
Sbjct: 1949 NTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNL-DGSYRCICPPGYSL 2006
Query: 309 -GVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPC-- 363
CE +D C +P CA GTCS T F C C G+ C
Sbjct: 2007 QNEKCEDIDE-CVEEPEICALGTCS--NTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYA 2063
Query: 364 -LHGASC-----RDHLDGFTCECA---DGWTGPA--CAEDVDECSGRSMTEGA---LGPC 409
G C R+H C CA +GW P C + DE + G+ +GP
Sbjct: 2064 KFEGGKCSSPKSRNHSKQECC-CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 2122
Query: 410 VNAA--------------ACNNTAGGYSCACLAGW--TGRDCETNVDDCT-GQCLHGATC 452
+A C NT G Y C C G+ G +C + D+C+ G TC
Sbjct: 2123 DSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNGTC 2181
Query: 453 IDLVDDFHCACAAGYAG---RTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF---- 505
+++ F C C G+ TC D+++CA P CV+ +Y C CPVG+
Sbjct: 2182 KNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLRE 2240
Query: 506 SGTNCEDDRDHC--AGSPC-GNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
C+D+ D C C C Y C C PG+ QR D + C
Sbjct: 2241 DRRMCKDE-DECEEGKHDCTEKQMECKNLIGTYMCICGPGY------QRRP-DGEGC--- 2289
Query: 563 VEESE-RCAEGMCANGGTCVREEGSW 587
V+E+E + G+C N G C+ GS+
Sbjct: 2290 VDENECQTKPGICEN-GRCLNTRGSY 2314
Score = 107 bits (258), Expect = 1e-22
Identities = 94/326 (28%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCS 330
D++ C G C N + C C GF D CE +D C P
Sbjct: 1766 DIDECREIPGVCENGVCINMV-GSFRCECPVGFFYNDKLLVCEDIDE-CQNGPVCQRNAE 1823
Query: 331 LAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG 386
T + C C G+ G C HG C D + F C C TG
Sbjct: 1824 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCLCH---TG 1879
Query: 387 PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDDCT 443
+D C + E C N C NT G ++C C G+ DC +VD+C
Sbjct: 1880 FKTNDDQTMCL--DINECERDACGNGT-CRNTIGSFNCRCNHGFILSHNNDC-IDVDECA 1935
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA--PRPCTNGGECVDLL 494
G CI+ V F C C GY GRTC +D+++C PR C G C +L
Sbjct: 1936 SGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLD 1993
Query: 495 NAYRCICPVGFSGTN--CEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
+YRCICP G+S N CE D D C P C G C + + C C G++ + +
Sbjct: 1994 GSYRCICPPGYSLQNEKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGR 2051
Query: 551 RAARDRKTCSVLVEESERCAEGMCAN 576
R R + E +C+ N
Sbjct: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRN 2077
Score = 98.7 bits (235), Expect = 9e-20
Identities = 130/511 (25%), Positives = 189/511 (36%), Gaps = 81/511 (15%)
Query: 205 DNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGW--RGELC---SQCQPYPGCKHGYCNG- 256
D C++P VCK G C T G C+C G+ G C +C C +G C
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYR----CECPFGYILAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 257 -SSWDCTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE 313
++CTC+ + G ++ +D+N C + P C NT Y C+C G+ +
Sbjct: 2185 IGGFECTCEEGFEPGPMMTCEDINECAQN-PLLCAFRCVNTY-GSYECKCPVGYVLREDR 2242
Query: 314 RV---DNPC--APQPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPC 363
R+ ++ C C + C C G+ G G C
Sbjct: 2243 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2302
Query: 364 LHGASCRDHLDGFTCECADGWTG-PACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGY 422
+G C + +TCEC DG+T P E +D G TE C ++ N
Sbjct: 2303 ENGR-CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 423 SCACLAG--WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
C C G W G CE C Q G F C G T D+D+C
Sbjct: 2362 ECCCDGGRGW-GPHCEI----CPFQ---GTVA------FKKLCPHGRGFMTNGADIDECK 2407
Query: 481 P--RPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGSPCGNGAACYTAQSD 534
C NG ECV+ +Y CIC G+ +GT+C D + C +P C +
Sbjct: 2408 VIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTSCV-DLNECNQAPKPCNFICKNTEGS 2465
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN---GGTCVREEGSWRXXX 591
Y C C G+ + R+ +D C+ + C + +C N G TC G
Sbjct: 2466 YQCSCPKGYILQE-DGRSCKDLDECAT---KQHNC-QFLCVNTIGGFTCKCPPG------ 2514
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
S + G C P + C C+ G +TG+ CE
Sbjct: 2515 ----FTQHHTSCIDNNECTSDINLCGSKGIC--QNTPGSFTCECQRGFSLDQTGSSCE-D 2567
Query: 648 LDLC-GSSPCRNGGRCVGGSGWWMCECVAGW 677
+D C G+ C++G C G + C C G+
Sbjct: 2568 VDECEGNHRCQHG--CQNIIGGYRCSCPQGY 2596
Score = 98.3 bits (234), Expect = 1e-19
Identities = 115/410 (28%), Positives = 158/410 (38%), Gaps = 94/410 (22%)
Query: 205 DNCEK-PVCKEG--CHPTHGRCDRPGDCDCRPGWR----GEL--CSQCQPYPG-CKHGYC 254
D C+ PVC+ C T G CDC+PG+R G+ ++CQ P C HG C
Sbjct: 1810 DECQNGPVCQRNAECINTAGSYR----CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQC 1865
Query: 255 --NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQH----GGTCENTAPDQYFCRCAEGF- 307
S+ C C T G + D C C+ GTC NT + CRC GF
Sbjct: 1866 IDTVGSFYCLCHT---GFKTNDDQTMCLDINECERDACGNGTCRNTI-GSFNCRCNHGFI 1921
Query: 308 --SGVDCERVDNPCAP---QPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXX 357
DC VD CA C +G C T F C C+ G+ G
Sbjct: 1922 LSHNNDCIDVDE-CASGNGNLCRNGQC--INTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
Query: 358 XASGPCLHGASCRDHLDG-FTCECADGWT--GPACAEDVDECSGRSMTEGALGPCVNAAA 414
C G +C+ +LDG + C C G++ C ED+DEC + E + C
Sbjct: 1979 LEPRKCAPG-TCQ-NLDGSYRCICPPGYSLQNEKC-EDIDEC----VEEPEI--CA-LGT 2028
Query: 415 CNNTAGGYSCACLAGW----TGRDC-ETNVDDCTGQCLHGATCIDLVDDFH----CACAA 465
C+NT G + C C G+ +GR C + + C + G C H C CA
Sbjct: 2029 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK-FEGGKCSSPKSRNHSKQECCCAL 2087
Query: 466 GYAG-----RTCSLDVDDCAPRPCTNG-------------------------GECVDLLN 495
G C + D+ + C G G+C++
Sbjct: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 2147
Query: 496 AYRCICPVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
+YRC CP G+ +G C D + G+PCGNG C + C C G+
Sbjct: 2148 SYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGF 2196
Score = 97.1 bits (231), Expect = 3e-19
Identities = 135/525 (25%), Positives = 188/525 (35%), Gaps = 84/525 (16%)
Query: 205 DNCE--KPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGEL--CSQCQPYPGCKHGYC- 254
D C+ + +C+ G C PT G C C+C G+ RGE +C+ P C G C
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCR----CECNKGFQLDLRGECIDVDECEKNP-CAGGECI 505
Query: 255 -NGSSWDCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF--- 307
N S+ C C + L +D++ C + + G C NT + C C GF
Sbjct: 506 NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT-DGSFHCVCNAGFHVT 564
Query: 308 -SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGP 362
G +CE +D C +G C F C C G+ G G
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMC--INEDGSFKCICKPGFQLASDGRYCKDINECETPGI 622
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCVNAAACNNTAG 420
C++G C + + CEC G + RS G G C+ T
Sbjct: 623 CMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKS 681
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
CA G C+ C Q + A ++ C++G + D+++CA
Sbjct: 682 ECCCASTEYAFGEPCQ----PCPAQ--NSA-------EYQALCSSGPGMTSAGSDINECA 728
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQS 533
P C N G C +L Y+CIC G+ +G NC D + S C NG C
Sbjct: 729 LDPDICPN-GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG-QCRNTPG 786
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVE-ESERCAEGMCANG-GTCVREEGSWRXXX 591
+ C C G+ K D KTC + E ES C G+C N G+ + E S
Sbjct: 787 SFVCTCPKGFIYK-------PDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP----SALPPGWA-----------CGCR 636
G L S+L W CG
Sbjct: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
Query: 637 EGR-TGALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
R G CE +D C P C+N G CV G + C+C +G T
Sbjct: 900 YSRIKGTQCE-DIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMT 942
Score = 93.9 bits (223), Expect = 3e-18
Identities = 101/375 (26%), Positives = 140/375 (37%), Gaps = 61/375 (16%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGS 257
C PGW GD + E + TH C + DC G +C CK GY G
Sbjct: 1350 CSPGWIGDGIKCTDLDECSNGTH-MCSQHADCKNTMG-----SYRCL----CKEGY-TGD 1398
Query: 258 SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCE 313
+ CT D + C ++LN CG G C N AP Y C C GF G CE
Sbjct: 1399 GFTCT-DLDE----CSENLNLCGN-------GQCLN-APGGYRCECDMGFVPSADGKACE 1445
Query: 314 RVDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGAS 368
+D P C GTC +L G F C C+ G+ G C+ G +
Sbjct: 1446 DIDECSLPNICVFGTCHNLPGL---FRCECEIGYELDRSGGNCTDVNECLDPTTCISG-N 1501
Query: 369 CRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
C + + C+C D P VD SG + AC+N G
Sbjct: 1502 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIG------- 1554
Query: 428 AGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-----DVDDCAPR 482
G + C ++ G ++ ++ C G R + D+D+C
Sbjct: 1555 VGVSKASCCCSLGKAWGTPCEMCPAVN-TSEYKILCPGGEGFRPNPITVILEDIDECQEL 1613
Query: 483 P-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHC-AGSPCGNGAACYTAQSDYYC 537
P GG+C++ +++C CP G+ T DD + C CG G CY +Y C
Sbjct: 1614 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT-CYNTVGNYTC 1672
Query: 538 HCAPGWT----GKNC 548
C P + G NC
Sbjct: 1673 ICPPDYMQVNGGNNC 1687
Score = 87.8 bits (208), Expect = 2e-16
Identities = 98/344 (28%), Positives = 128/344 (37%), Gaps = 68/344 (19%)
Query: 190 CTPDGDKHCLPGWQ----GDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C + +C PGW+ G+ C P+C+ C G C RP C C G C +
Sbjct: 59 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGD--GFCSRPNMCTCPSGQIAPSCGS-RS 115
Query: 246 YPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C NG S C C + G C Q + G C +GG C AP++ C
Sbjct: 116 IQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG----CLNGGRC--VAPNR--CA 167
Query: 303 CAEGFSGVDCER--VDNPC----APQPCAHGTCSLAGTTRGFTC-TCDRGWGGXXXXXXX 355
C GF+G CER PC + Q C G S T+ C T R WG
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCCATVGRAWG-------- 218
Query: 356 XXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
PC + A GF G AC +DVDEC + G C
Sbjct: 219 -----HPCEMCPAQPHPCRRGFIPNIRTG----AC-QDVDEC------QAIPGLC-QGGN 261
Query: 415 CNNTAGGYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
C NT G + C C AG + CE ++D+C+ G C G C + V + C C G+
Sbjct: 262 CINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGIC-EGGECTNTVSSYFCKCPPGF 319
Query: 468 AGRTCSLDVDDCAPRPC----TNG---GECVDLLNAYRCICPVG 504
D P C TNG + + +C C G
Sbjct: 320 YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 83.4 bits (197), Expect = 4e-15
Identities = 73/265 (27%), Positives = 100/265 (37%), Gaps = 27/265 (10%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF--SGVDCERVDNPCAPQPCAHGTCSLA 332
D++ C + C+HG C NT Y C C G+ +G +C D PC +GTC
Sbjct: 2127 DMDECKEPDVCKHG-QCINT-DGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCK-- 2182
Query: 333 GTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACA 390
GF CTC+ G+ G A P L C + + C+C G+
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGY---VLR 2239
Query: 391 EDVDECSGRSMTEGALGPCV-NAAACNNTAGGYSCACLAGWTGR-DCETNVD--DC---T 443
ED C E C C N G Y C C G+ R D E VD +C
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 444 GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPV 503
G C +G C++ + C C G+ T S + D+C G C + +C +
Sbjct: 2300 GICENG-RCLNTRGSYTCECNDGF---TASPNQDECLD---NREGYC--FTEVLQNMCQI 2350
Query: 504 GFSGTNCEDDRDHCAGSPCGNGAAC 528
G S N + C G G C
Sbjct: 2351 GSSNRNPVTKSECCCDGGRGWGPHC 2375
Score = 82.2 bits (194), Expect = 8e-15
Identities = 99/365 (27%), Positives = 135/365 (36%), Gaps = 74/365 (20%)
Query: 231 CRPGWR----GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNYCGTHEPC 285
C PGW+ G C C G+C+ + CTC + C + + +C C
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNM-CTCPSGQIAPSCGSRSIQHCNIR--C 123
Query: 286 QHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
+GG+C + C C +G+ G C + P C +G +A C C G
Sbjct: 124 MNGGSCSDD-----HCLCQKGYIGTHCGQ---PVCESGCLNGGRCVAPNR----CACTYG 171
Query: 346 WGGXXXXXXXXXXASGPC---LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR--S 400
+ G +GPC + C+ L G C T C V G
Sbjct: 172 FTGPQCERDYR---TGPCFTVISNQMCQGQLSGIVC------TKTLCCATVGRAWGHPCE 222
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVD 457
M PC N G AC +VD+C G C G CI+ V
Sbjct: 223 MCPAQPHPCRRGFIPNIRTG----AC----------QDVDECQAIPGLC-QGGNCINTVG 267
Query: 458 DFHCACAAGY----AGRTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGT 508
F C C AG+ + C D+D+C+ P GGEC + +++Y C CP GF GT
Sbjct: 268 SFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 509 NCEDDR-DHC----AGSPCGNGAACYTAQSDYYC---HC-APGWT--GKNCTQRAARD-R 556
C D R +C C N + C C +PG T + C RA D
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFN 386
Query: 557 KTCSV 561
K CSV
Sbjct: 387 KLCSV 391
Score = 77.4 bits (182), Expect = 2e-13
Identities = 111/474 (23%), Positives = 165/474 (34%), Gaps = 73/474 (15%)
Query: 237 GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
G C+ CQ P C GY C +D++ C G C NT
Sbjct: 884 GSPCTLCQVDPICGKGYSRIKGTQC------------EDIDECEVFPGVCKNGLCVNTR- 930
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPC------AHGTCSLAGTTRGFTCTCDRGWGGXX 350
+ C+C G + R+ + C T +AG R C C G
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGT 990
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
+ P R GF + + G +D++EC +
Sbjct: 991 EECEECPMRNTPEYEELCPRG--PGFATK--EITNGKPFFKDINECK-------MIPSLC 1039
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDCETNVDDC---TGQCLHGATCIDLVDDFHCAC 463
C NT G + C C +G+ R+C T++D+C C G C++ DF C C
Sbjct: 1040 THGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRG-QCVNTPGDFECKC 1097
Query: 464 AAGYAG-----RTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFS---GTNCEDDR 514
GY + C +D+D+C P GG C + +YRC CP G + D
Sbjct: 1098 DEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1156
Query: 515 DHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
+ C S C NG C Y C C PG+ + DR C V ++E G
Sbjct: 1157 NECELSAHLCPNG-RCVNLIGKYQCACNPGY-------HSTPDRLFC-VDIDECS-IMNG 1206
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA 632
C C EGS+ GG C + +P +
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1262
Query: 633 CGCREGRTGA----LCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTGE 680
C C +G + C + ++ C +P C + G C G ++C C G++G+
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGK 1314
Score = 65.7 bits (153), Expect = 8e-10
Identities = 61/226 (26%), Positives = 89/226 (39%), Gaps = 36/226 (15%)
Query: 474 LDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCAGSP-CGNGA 526
+D+D+C P C NG C++++ ++RC CPVGF + CE D D C P C A
Sbjct: 1765 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNA 1822
Query: 527 ACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGS 586
C Y C C PG+ + Q DR C + +C++ G C+ GS
Sbjct: 1823 ECINTAGSYRCDCKPGYRFTSTGQ--CNDRNECQEI--------PNICSH-GQCIDTVGS 1871
Query: 587 WRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG---RTGAL 643
+ D GTC + + C C G
Sbjct: 1872 F--YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTI--GSFNCRCNHGFILSHNND 1927
Query: 644 CELSLDLCGS---SPCRNGGRCVGGSGWWMCECVAGW----TGETC 682
C + +D C S + CRN G+C+ G + C+C G+ G TC
Sbjct: 1928 C-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTC 1971
Score = 43.6 bits (98), Expect = 0.004
Identities = 50/187 (26%), Positives = 66/187 (35%), Gaps = 19/187 (10%)
Query: 499 CICPVGFSGTNCEDDR-DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C CP G +C HC C NG +C SD +C C G+ G +C Q
Sbjct: 100 CTCPSGQIAPSCGSRSIQHC-NIRCMNGGSC----SDDHCLCQKGYIGTHCGQPVCESGC 154
Query: 558 TCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD-SXXXXXXXXXXXXXX 616
RCA G C R+ + S
Sbjct: 155 LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG 214
Query: 617 QAGGTCLPSALPPGWACGCREG-----RTGALCELSLDLCGSSP--CRNGGRCVGGSGWW 669
+A G P + P CR G RTGA C+ +D C + P C+ GG C+ G +
Sbjct: 215 RAWGH--PCEMCPAQPHPCRRGFIPNIRTGA-CQ-DVDECQAIPGLCQ-GGNCINTVGSF 269
Query: 670 MCECVAG 676
C+C AG
Sbjct: 270 ECKCPAG 276
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C++G G C +C S C NGGRCV + C C G+TG C
Sbjct: 134 CLCQKGYIGTHC--GQPVCESG-CLNGGRCVAPN---RCACTYGFTGPQC 177
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 120 bits (290), Expect = 2e-26
Identities = 107/361 (29%), Positives = 151/361 (41%), Gaps = 55/361 (15%)
Query: 229 CDCRPGWRG----ELCS---QCQPYPGCKHGYCNGS--SWDCTCDTNWG----GILCDQD 275
C C PG++ + C+ +C G C S S++C+C + G C D
Sbjct: 289 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-AD 347
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-SGVDCER-VD-NPCAPQP--CAHGTCS 330
++ C + GG C N P +Y C C +GF + +D + +D N C C G C
Sbjct: 348 IDECENNPDICDGGQCTNI-PGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 406
Query: 331 LAGTTRGFTCTCDRGWG---GXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECADGWT 385
T F C C G+ G G C ASC + F C C +GW
Sbjct: 407 --NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI 464
Query: 386 GPAC-AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE-TNVDDCT 443
G D+DECS + C A C NT G Y CAC G+TG ++VD+C
Sbjct: 465 GNGIKCIDLDECSNGTHQ------CSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECA 518
Query: 444 ---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNA 496
C +G C+++ + C C G+ R+C D+D+C+ + G C +L
Sbjct: 519 ENINLCENG-QCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGM 576
Query: 497 YRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGW----TGKN 547
+ CIC G+ +G NC D D CA C NG C Y C+C P + TG
Sbjct: 577 FHCICDDGYELDRTGGNC-TDIDECADPINCVNG-LCVNTPGRYECNCPPDFQLNPTGVG 634
Query: 548 C 548
C
Sbjct: 635 C 635
Score = 118 bits (284), Expect = 1e-25
Identities = 100/342 (29%), Positives = 143/342 (41%), Gaps = 55/342 (16%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHG 288
CD GW G C C P PG + + C G +D++ C
Sbjct: 1476 CDGGRGW-GHQCELC-PLPGT-------AQYKKICPHGPGYTTDGRDIDECKVMPNLCTN 1526
Query: 289 GTCENTAPDQYFCRCAEGF----SGVDCERVDNPC-APQPCAHGTCSLAGTTRGFTCTCD 343
G C NT + C C G+ SG C +D +P+PC + C T + C+C
Sbjct: 1527 GQCINTM-GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICK--NTEGSYQCSCP 1582
Query: 344 RGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTG--PACAEDVDEC 396
RG+ G C C + L GFTC+C G+T AC ++ +EC
Sbjct: 1583 RGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPGFTQHHTACIDN-NEC 1639
Query: 397 SGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW----TGRDCETNVDDCTG--QCLHGA 450
+ GA G C NT G +SC C G+ TG +CE +VD+C G +C HG
Sbjct: 1640 GSQPSLCGAKG------ICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG- 1691
Query: 451 TCIDLVDDFHCACAAGYAGR---TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS- 506
C +++ + C C GY +D ++C+ C + L +Y+C CP GFS
Sbjct: 1692 -CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSF 1750
Query: 507 ---GTNCEDDRDHCAGS--PCGNGAACYTAQSDYYCHCAPGW 543
+ C D + C+ S PC G C + Y C C PG+
Sbjct: 1751 DQFSSACHDVNE-CSSSKNPCNYG--CSNTEGGYLCGCPPGY 1789
Score = 118 bits (283), Expect = 1e-25
Identities = 134/516 (25%), Positives = 193/516 (37%), Gaps = 68/516 (13%)
Query: 196 KHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKH-- 251
+ C W D C HP G+ R C C G W G C +C P PG K
Sbjct: 65 EQCYLKWDEDEC--------IHPVPGKF-RMDACCCAVGAAW-GTECEEC-PKPGTKEYE 113
Query: 252 GYC-NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS-- 308
C G+ + D G +D+N C G C NT + CRC GF+
Sbjct: 114 TLCPRGAGFANRGDVLTGRPFY-KDINECKAFPGMCTYGKCRNTI-GSFKCRCNSGFALD 171
Query: 309 --GVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----G 361
+C +D +P C G C T F C C G+
Sbjct: 172 MEERNCTDIDECRISPDLCGSGIC--VNTPGSFECECFEGYESGFMMMKNCMDIDECERN 229
Query: 362 PCL-HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P L G +C + F C+C G ED + + S+++ C N C N G
Sbjct: 230 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL---CRNGK-CVNMIG 285
Query: 421 GYSCACLAGWTG---RDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GR 470
Y C+C G+ R T++D+C G C C + + C+C+ GYA GR
Sbjct: 286 TYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYECSCSEGYALMPDGR 343
Query: 471 TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSPCGNG 525
+C+ D+D+C P +GG+C ++ YRC+C GF + C D + S
Sbjct: 344 SCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 402
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + CHC G++ K T T V+E E A C +C+ G
Sbjct: 403 GECENTKGSFICHCQLGYSVKKGT--------TGCTDVDECEIGAHN-CDMHASCLNIPG 453
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
S++ C+ + P + C C EG TG
Sbjct: 454 SFKCSCREGWIGNGIKCIDLDECSNGTHQCS-INAQCVNT--PGSYRCACSEGFTGDGFT 510
Query: 646 LS-LDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
S +D C + C NG +C+ G + CEC G+T
Sbjct: 511 CSDVDECAENINLCENG-QCLNVPGAYRCECEMGFT 545
Score = 116 bits (278), Expect = 6e-25
Identities = 131/506 (25%), Positives = 199/506 (39%), Gaps = 83/506 (16%)
Query: 219 THGRCDRP-GD--CDCRPGWRGEL----CS---QCQPYPG-CKHGYCNGS--SWDCTCDT 265
T+G+C G C C G+ ++ C+ +C+ P C G C + S++C C
Sbjct: 149 TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFE 208
Query: 266 NW-GGILCDQ---DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDN 317
+ G + + D++ C + GGTC NT + C C G S DC + N
Sbjct: 209 GYESGFMMMKNCMDIDECERNPLLCRGGTCVNTE-GSFQCDCPLGHELSPSREDCVDI-N 266
Query: 318 PCAPQP--CAHGTC-SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGA---SCRD 371
C+ C +G C ++ GT + C+C+ G+ ++G C +
Sbjct: 267 ECSLSDNLCRNGKCVNMIGT---YQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTN 323
Query: 372 HLDGFTCECADGWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
+ C C++G+ G +CA D+DEC + C N G Y C C
Sbjct: 324 SEGSYECSCSEGYALMPDGRSCA-DIDECENNP-------DICDGGQCTNIPGEYRCLCY 375
Query: 428 AGW-TGRDCETNVD--DC---TGQCLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDD 478
G+ D +T +D +C + C+ G C + F C C GY+ G T DVD+
Sbjct: 376 DGFMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDE 434
Query: 479 C--APRPCTNGGECVDLLNAYRCICPVGFSGTNCED-DRDHCAGSP--CGNGAACYTAQS 533
C C C+++ +++C C G+ G + D D C+ C A C
Sbjct: 435 CEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 494
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE--GMCANGGTCVREEGSWRXXX 591
Y C C+ G+TG D TCS + + CAE +C N G C+ G++R
Sbjct: 495 SYRCACSEGFTG---------DGFTCS----DVDECAENINLCEN-GQCLNVPGAYR-CE 539
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG----RTGALCELS 647
DS GTC + LP + C C +G RTG C
Sbjct: 540 CEMGFTPASDSRSCQDIDECSFQNICVFGTC--NNLPGMFHCICDDGYELDRTGGNC-TD 596
Query: 648 LDLCGSSPCRNGGRCVGGSGWWMCEC 673
+D C G CV G + C C
Sbjct: 597 IDECADPINCVNGLCVNTPGRYECNC 622
Score = 102 bits (245), Expect = 6e-21
Identities = 101/361 (27%), Positives = 141/361 (39%), Gaps = 47/361 (13%)
Query: 242 QCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCD-----QDLNYCGTHEPCQHGGTCENTA 295
+CQ PG C+ G C + C+ G L + +D++ C H GTC NT
Sbjct: 717 ECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL 776
Query: 296 PDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCS--LAGTTRGFTCTCDRGWGGX 349
+ Y C C + G +C + + TC L C C G
Sbjct: 777 GN-YTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKA 835
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPC 409
G C ++ GFT D TG A D+DEC + G C
Sbjct: 836 WNKPCEPCPTPGTADFKTIC-GNIPGFTF---DIHTGKAV--DIDEC------KEIPGIC 883
Query: 410 VNAAACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCA 462
N C N G + C C G++ D CE ++D+C+ C A CI+ + C
Sbjct: 884 ANGV-CINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCE 941
Query: 463 CAAGY--AGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCED---DRD 515
CAAG+ + +D ++C P C++G CVDL +Y+CIC GF + + D D
Sbjct: 942 CAAGFKLSPNGACVDRNECLEIPNVCSHG-LCVDLQGSYQCICHNGFKASQDQTMCMDVD 1000
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCA 575
C PCGNG C Y C C PG+ + D CS + C G C
Sbjct: 1001 ECERHPCGNG-TCKNTVGSYNCLCYPGF--ELTHNNDCLDIDECSSFF--GQVCRNGRCF 1055
Query: 576 N 576
N
Sbjct: 1056 N 1056
Score = 99.5 bits (237), Expect = 5e-20
Identities = 113/441 (25%), Positives = 163/441 (36%), Gaps = 62/441 (14%)
Query: 164 LCQPNY-YNT--TCTTFCRPRDDKF-GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPT 219
+C P YNT T C P + G ++C C + G CE + + T
Sbjct: 766 VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENEL---PFNVT 822
Query: 220 HGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKH--GYCNGSSWDCTCDTNWGGILCDQD 275
C C G W + C C P PG C G+ T D + G + D
Sbjct: 823 KRMCC----CTYNVGKAWN-KPCEPC-PTPGTADFKTIC-GNIPGFTFDIHTGKAV---D 872
Query: 276 LNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPCAHGTCSL 331
++ C G C N + C C GFS D CE +D
Sbjct: 873 IDECKEIPGICANGVCINQI-GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC 931
Query: 332 AGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
+ + C C G+ G C HG C D + C C +G+
Sbjct: 932 INSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCICHNGFKAS 990
Query: 388 ---ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETNVDD 441
DVDEC PC N C NT G Y+C C G+ DC ++D+
Sbjct: 991 QDQTMCMDVDECERH--------PCGNGT-CKNTVGSYNCLCYPGFELTHNNDC-LDIDE 1040
Query: 442 CT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCT-NGGECVDL 493
C+ GQ C + + F C C GY G+ C +D ++C P + + G C +L
Sbjct: 1041 CSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNL 1099
Query: 494 LNAYRCICPVGF--SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCT 549
++RCICP G+ NC D + C P C G +C + C C PG+ +
Sbjct: 1100 EGSFRCICPPGYEVKSENCIDINE-CDEDPNICLFG-SCTNTPGGFQCLCPPGFVLSDNG 1157
Query: 550 QRAARDRKTCSVLVEESERCA 570
+R R++ E+ +C+
Sbjct: 1158 RRCFDTRQSFCFTNFENGKCS 1178
Score = 99.1 bits (236), Expect = 7e-20
Identities = 114/474 (24%), Positives = 180/474 (37%), Gaps = 64/474 (13%)
Query: 241 SQCQPYPG-CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGT--HEPCQ---HGGTCE 292
++C+ +PG C +G C S S+ C C G+ D C E C C
Sbjct: 21 NECEVFPGVCPNGRCVNSKGSFHCECPE---GLTLDGTGRVCLDIRMEQCYLKWDEDECI 77
Query: 293 NTAPDQY---FCRCAEGFS-GVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
+ P ++ C CA G + G +CE P+P +L GF D G
Sbjct: 78 HPVPGKFRMDACCCAVGAAWGTECEE-----CPKPGTKEYETLCPRGAGFANRGDVLTGR 132
Query: 349 XXXXXXXXXXA-SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALG 407
A G C +G CR+ + F C C G+ A D++E + + E +
Sbjct: 133 PFYKDINECKAFPGMCTYG-KCRNTIGSFKCRCNSGF-----ALDMEERNCTDIDECRIS 186
Query: 408 PCV-NAAACNNTAGGYSCACLAGWTG-----RDCETNVDDCTGQCL--HGATCIDLVDDF 459
P + + C NT G + C C G+ ++C ++D+C L G TC++ F
Sbjct: 187 PDLCGSGICVNTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSF 245
Query: 460 HCACAAGYA---GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT----NC 510
C C G+ R +D+++C+ C NG +CV+++ Y+C C G+ T C
Sbjct: 246 QCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATPDRQGC 304
Query: 511 EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
D D C G C ++ Y C C+ G+ D ++C+ ++E E
Sbjct: 305 -TDIDECMIMNGGCDTQCTNSEGSYECSCSEGYA-------LMPDGRSCAD-IDECENNP 355
Query: 571 EGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPG 630
+ +C +GG C G +R G C
Sbjct: 356 D-IC-DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGEC--ENTKGS 411
Query: 631 WACGCREG---RTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGWTG 679
+ C C+ G + G +D C G+ C C+ G + C C GW G
Sbjct: 412 FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG 465
Score = 95.5 bits (227), Expect = 8e-19
Identities = 99/396 (25%), Positives = 152/396 (38%), Gaps = 61/396 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GPCLHGAS-CRDHLDGF 376
P C +G C T F C C+ G+ P L G+ C + F
Sbjct: 145 PGMCTYGKCR--NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 202
Query: 377 TCECADGWTGPAC----AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW-- 430
CEC +G+ D+DEC + C C NT G + C C G
Sbjct: 203 ECECFEGYESGFMMMKNCMDIDECERNPLL------C-RGGTCVNTEGSFQCDCPLGHEL 255
Query: 431 --TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG---RTCSLDVDDCAPR 482
+ DC ++++C+ C +G C++++ + C+C GY R D+D+C
Sbjct: 256 SPSREDC-VDINECSLSDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECM-- 311
Query: 483 PCTNGG---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSP--CGNGAACYTAQS 533
NGG +C + +Y C C G++ G +C D D C +P C +G C
Sbjct: 312 -IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI-DECENNPDIC-DGGQCTNIPG 368
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+Y C C G+ A+ D KTC ++ +E G C +GS+
Sbjct: 369 EYRCLCYDGFM-------ASMDMKTC---IDVNECDLNSNICMFGECENTKGSFICHCQL 418
Query: 594 XXXXXXXDSXXXXXXXXXXXXXX-QAGGTCLPSALPPGWACGCREGRTG-ALCELSLDLC 651
+ +CL +P + C CREG G + + LD C
Sbjct: 419 GYSVKKGTTGCTDVDECEIGAHNCDMHASCLN--IPGSFKCSCREGWIGNGIKCIDLDEC 476
Query: 652 --GSSPCRNGGRCVGGSGWWMCECVAGWTGE--TCA 683
G+ C +CV G + C C G+TG+ TC+
Sbjct: 477 SNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS 512
Score = 95.1 bits (226), Expect = 1e-18
Identities = 72/224 (32%), Positives = 102/224 (45%), Gaps = 40/224 (17%)
Query: 317 NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWG----GXXXXXXXXXXASGPCLHGASCR 370
N C P C++G C T F C C G+ G PC +G +C
Sbjct: 1237 NECLESPGICSNGQC--INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG-TCT 1293
Query: 371 DHLDGFTCECADGWT-GPAC-AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
+ + F C C +G+ GP ED++EC A P + A C NT G Y C C
Sbjct: 1294 NVIGSFECNCNEGFEPGPMMNCEDINEC--------AQNPLLCAFRCMNTFGSYECTCPI 1345
Query: 429 GWTGRDCET---NVDDCTGQCLH-----GATCIDLVDDFHCACAAGYA----GRTCSLDV 476
G+ R+ + ++D+C + LH G C +L+ F C C G A G C +D
Sbjct: 1346 GYALREDQKMCKDLDECA-EGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDE 1403
Query: 477 DDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCEDDR 514
++C +P C NG CV+++ +YRC C GF SGT C D+R
Sbjct: 1404 NECRTKPGICENG-RCVNIIGSYRCECNEGFQSSSSGTECLDNR 1446
Score = 85.0 bits (201), Expect = 1e-15
Identities = 79/291 (27%), Positives = 115/291 (39%), Gaps = 44/291 (15%)
Query: 294 TAPDQYFCRCAEGFSGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGW-----G 347
TA + C G++ D +D P C +G C T F C C G+ G
Sbjct: 1494 TAQYKKICPHGPGYT-TDGRDIDECKVMPNLCTNGQC--INTMGSFRCFCKVGYTTDISG 1550
Query: 348 GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGRSMTE 403
+ PC + C++ + C C G+ G C +D+DEC +
Sbjct: 1551 TSCIDLDECSQSPKPCNY--ICKNTEGSYQCSCPRGYVLQEDGKTC-KDLDECQTKQHNC 1607
Query: 404 GALGPCVNAAACNNTAGGYSCACLAGWTGRD--CETNVDDCTGQ---CLHGATCIDLVDD 458
L C NT GG++C C G+T C N ++C Q C C +
Sbjct: 1608 QFL--------CVNTLGGFTCKCPPGFTQHHTACIDN-NECGSQPSLCGAKGICQNTPGS 1658
Query: 459 FHCACAAGYA----GRTCSLDVDDC-APRPCTNGGECVDLLNAYRCICPVGF----SGTN 509
F C C G++ G C DVD+C C +G C ++L YRC CP G+
Sbjct: 1659 FSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQ 1715
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCS 560
C D+ + + CG+ A+CY Y C C G++ + A D CS
Sbjct: 1716 CVDENECSNPNACGS-ASCYNTLGSYKCACPSGFSFDQFSS-ACHDVNECS 1764
Score = 83.8 bits (198), Expect = 3e-15
Identities = 105/387 (27%), Positives = 144/387 (37%), Gaps = 75/387 (19%)
Query: 212 CKEGCH--PTHGRC-DRPGD--CDCRPGWRGELCSQCQPYPGCKHG--YCN--------G 256
C+ G H H C + PG C CR GW G +C C +G C+
Sbjct: 435 CEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGI-KCIDLDECSNGTHQCSINAQCVNTP 493
Query: 257 SSWDCTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD--- 311
S+ C C + G C D++ C + G C N P Y C C GF+
Sbjct: 494 GSYRCACSEGFTGDGFTCS-DVDECAENINLCENGQCLNV-PGAYRCECEMGFTPASDSR 551
Query: 312 -CERVDNPCAPQPCAHGTCS-LAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCL 364
C+ +D C GTC+ L G F C CD G+ GG C+
Sbjct: 552 SCQDIDECSFQNICVFGTCNNLPGM---FHCICDDGYELDRTGGNCTDIDECADPIN-CV 607
Query: 365 HGASCRDHLDGFTCECA-DGWTGPACAEDVDECSGRSMTEGALGPCVNAA-ACNNTAG-- 420
+G C + + C C D P VD G + GP + + +CN G
Sbjct: 608 NGL-CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLK--FGPRGDGSLSCNTEIGVG 664
Query: 421 --GYSCACLAG--WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL-- 474
SC C G W G CET C +T +++ C G R +
Sbjct: 665 VSRSSCCCSLGKAW-GNPCET----CPPV---NST------EYYTLCPGGEGFRPNPITI 710
Query: 475 ---DVDDCAPRP-CTNGGECVDLLNAYRCICPVGF---SGTNCEDDRDHCAGSP--CGNG 525
D+D+C P GG C++ +++C CP G+ T +D D C P CG G
Sbjct: 711 ILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG 770
Query: 526 AACYTAQSDYYCHCAPGWT----GKNC 548
CY +Y C C P + G NC
Sbjct: 771 -TCYNTLGNYTCICPPEYMQVNGGHNC 796
Score = 81.0 bits (191), Expect = 2e-14
Identities = 99/428 (23%), Positives = 141/428 (32%), Gaps = 57/428 (13%)
Query: 274 QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCAPQPCAHGTC 329
+D+N C G C NT + C C G++ GV C D PC +GTC
Sbjct: 1234 EDVNECLESPGICSNGQCINT-DGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTC 1292
Query: 330 SLAGTTRGFTCTCDRGW--GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGP 387
+ F C C+ G+ G A P L C + + C C G+
Sbjct: 1293 T--NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGY--- 1347
Query: 388 ACAEDVDECSGRSMTEGALGPCVN-AAACNNTAGGYSCACLAGWTGR-DCETNVD--DC- 442
A ED C L C + C N G + C C G R D E VD +C
Sbjct: 1348 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 1407
Query: 443 --TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
G C +G C++++ + C C G+ + + C + + + + I
Sbjct: 1408 TKPGICENG-RCVNIIGSYRCECNEGFQSSSSGTE--------CLDNRQGLCFAEVLQTI 1458
Query: 501 CPVGFSGTNCEDDRDHCAGSPCGNGAACY------TAQSDYYCHCAPGWTGKNCTQRAAR 554
C + S N + C G G C TAQ C PG+T R
Sbjct: 1459 CQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYT------TDGR 1512
Query: 555 DRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
D C V+ +C N G C+ GS+R D
Sbjct: 1513 DIDECKVM--------PNLCTN-GQCINTMGSFR---CFCKVGYTTDISGTSCIDLDECS 1560
Query: 615 XXQAGGTCLPSALPPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGWWM 670
+ + C C G G C+ LD C + CV G +
Sbjct: 1561 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFT 1619
Query: 671 CECVAGWT 678
C+C G+T
Sbjct: 1620 CKCPPGFT 1627
Score = 80.2 bits (189), Expect = 3e-14
Identities = 107/430 (24%), Positives = 160/430 (37%), Gaps = 77/430 (17%)
Query: 208 EKP-VCKEG-CHPTHG--RCDRPGDCDCR-PGWRGELCSQCQPYPGCKHGYCNG--SSWD 260
E P +C G C T G RC+ P + G R +C C +G C S++
Sbjct: 1241 ESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFE 1300
Query: 261 CTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD----CER 314
C C+ + G ++ +D+N C + P C NT Y C C G++ + C+
Sbjct: 1301 CNCNEGFEPGPMMNCEDINECAQN-PLLCAFRCMNTF-GSYECTCPIGYALREDQKMCKD 1358
Query: 315 VDNPCAP--QPCAHGTCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGA 367
+D CA C F C C G G G C +G
Sbjct: 1359 LDE-CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGR 1417
Query: 368 SCRDHLDGFTCECADGWTGPACA-EDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCAC 426
C + + + CEC +G+ + E +D G E C A++ N C C
Sbjct: 1418 -CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCC 1476
Query: 427 LAG--WTGRDCET------------------------NVDDCT---GQCLHGATCIDLVD 457
G W G CE ++D+C C +G CI+ +
Sbjct: 1477 DGGRGW-GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQ-CINTMG 1534
Query: 458 DFHCACAAGY----AGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGF----SG 507
F C C GY +G +C +D+D+C+ P+PC C + +Y+C CP G+ G
Sbjct: 1535 SFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNY--ICKNTEGSYQCSCPRGYVLQEDG 1591
Query: 508 TNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
C+ D D C C + C C PG+T + A D C +
Sbjct: 1592 KTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHH---TACIDNNECG---SQPS 1644
Query: 568 RC-AEGMCAN 576
C A+G+C N
Sbjct: 1645 LCGAKGICQN 1654
Score = 79.4 bits (187), Expect = 6e-14
Identities = 126/498 (25%), Positives = 181/498 (36%), Gaps = 91/498 (18%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCT--------PDGDK-HCLPGWQGDN--C-EKPV 211
CQ Y TT C D+ + G ++C P K C GW G+ C +
Sbjct: 416 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDE 475
Query: 212 CKEGCHPT--HGRC-DRPGD--CDCRPGWRGE--LCS---QCQPYPG-CKHGYCNG--SS 258
C G H + +C + PG C C G+ G+ CS +C C++G C +
Sbjct: 476 CSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGA 535
Query: 259 WDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVD 311
+ C C+ + QD++ C C G TC N P + C C +G+ +G +
Sbjct: 536 YRCECEMGFTPASDSRSCQDIDECSFQNICVFG-TCNNL-PGMFHCICDDGYELDRTGGN 593
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C +D P C +G C T + C C + G C R
Sbjct: 594 CTDIDECADPINCVNGLC--VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRG 651
Query: 372 HLDG-FTC--ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
DG +C E G + +C + + G PC N+T C
Sbjct: 652 --DGSLSCNTEIGVGVSRSSCCCSLGKAWGN--------PCETCPPVNSTEYYTLCPGGE 701
Query: 429 GWTGRDCET---NVDDCT---GQCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDD 478
G+ ++D+C G C G CI+ F C C GY R C D+D+
Sbjct: 702 GFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDE 759
Query: 479 CAPRPCTNG-GECVDLLNAYRCICPVGF----SGTNCEDDR-DHC----AGSPCGNGAAC 528
C P G G C + L Y CICP + G NC D R C G+ C N
Sbjct: 760 CFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPF 819
Query: 529 YTAQSDYYC--HCAPGWTG--KNCTQRAARDRKT-CSVL-----------VEESERCAE- 571
+ C + W + C D KT C + + + C E
Sbjct: 820 NVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI 879
Query: 572 -GMCANGGTCVREEGSWR 588
G+CAN G C+ + GS+R
Sbjct: 880 PGICAN-GVCINQIGSFR 896
Score = 50.4 bits (115), Expect = 3e-05
Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 25/183 (13%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCN-GSSWDCTCDTNWGGI 270
C G H C +C +P G CQ PG C G S D T G+
Sbjct: 1622 CPPGFTQHHTACIDNNECGSQPSLCGAK-GICQNTPGSFSCECQRGFSLDAT------GL 1674
Query: 271 LCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEG----FSGVDCERVDNPCAPQPCAH 326
C+ D++ C + CQHG C+N Y C C +G + C +N C+ P A
Sbjct: 1675 NCE-DVDECDGNHRCQHG--CQNIL-GGYRCGCPQGYIQHYQWNQCVD-ENECS-NPNAC 1728
Query: 327 GTCSLAGTTRGFTCTCDRG-----WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECA 381
G+ S T + C C G + + PC +G C + G+ C C
Sbjct: 1729 GSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCP 1786
Query: 382 DGW 384
G+
Sbjct: 1787 PGY 1789
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 120 bits (289), Expect = 3e-26
Identities = 135/516 (26%), Positives = 194/516 (37%), Gaps = 68/516 (13%)
Query: 196 KHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPG--WRGELCSQCQPYPGCKH-- 251
+ C W D C HP G+ R C C G W G C +C P PG K
Sbjct: 249 EQCYLKWDEDEC--------IHPVPGKF-RMDACCCAVGAAW-GTECEEC-PKPGTKEYE 297
Query: 252 GYC-NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS-- 308
C G+ + D G +D+N C G C NT + CRC GF+
Sbjct: 298 TLCPRGAGFANRGDVLTGRPFY-KDINECKAFPGMCTYGKCRNTI-GSFKCRCNSGFALD 355
Query: 309 --GVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG---- 361
+C +D +P C G C T F C C G+ G
Sbjct: 356 MEERNCTDIDECRISPDLCGSGIC--VNTPGSFECECFEGYESGFMMMKNCMDIDGCERN 413
Query: 362 PCL-HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P L G +C + F C+C G ED + + S+++ C N C N G
Sbjct: 414 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL---CRNGK-CVNMIG 469
Query: 421 GYSCACLAGWTG---RDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGYA----GR 470
Y C+C G+ R T++D+C G C C + + C+C+ GYA GR
Sbjct: 470 TYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYECSCSEGYALMPDGR 527
Query: 471 TCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSPCGNG 525
+C+ D+D+C P +GG+C ++ YRC+C GF + C D + S
Sbjct: 528 SCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF 586
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C + + CHC G++ K T T V+E E A C +C+ G
Sbjct: 587 GECENTKGSFICHCQLGYSVKKGT--------TGCTDVDECEIGAHN-CDMHASCLNIPG 637
Query: 586 SWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCE 645
S++ C+ + P + C C EG TG
Sbjct: 638 SFKCSCREGWIGNGIKCIDRDECSNGTHQCS-INAQCVNT--PGSYRCACSEGFTGDGFT 694
Query: 646 LS-LDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
S +D C + C NG +C+ G + CEC G+T
Sbjct: 695 CSDVDECAENINLCENG-QCLNVPGAYRCECEMGFT 729
Score = 90.2 bits (214), Expect = 3e-17
Identities = 97/396 (24%), Positives = 150/396 (37%), Gaps = 61/396 (15%)
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GPCLHGAS-CRDHLDGF 376
P C +G C T F C C+ G+ P L G+ C + F
Sbjct: 329 PGMCTYGKCR--NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 386
Query: 377 TCECADGWTGPAC----AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW-- 430
CEC +G+ D+D C + C C NT G + C C G
Sbjct: 387 ECECFEGYESGFMMMKNCMDIDGCERNPLL------C-RGGTCVNTEGSFQCDCPLGHEL 439
Query: 431 --TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG---RTCSLDVDDCAPR 482
+ DC ++++C+ C +G C++++ + C+C GY R D+D+C
Sbjct: 440 SPSREDC-VDINECSLSDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECM-- 495
Query: 483 PCTNGG---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSP--CGNGAACYTAQS 533
NGG +C + +Y C C G++ G +C D D C +P C +G C
Sbjct: 496 -IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI-DECENNPDIC-DGGQCTNIPG 552
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXX 593
+Y C C G+ A+ D KTC ++ +E G C +GS+
Sbjct: 553 EYRCLCYDGFM-------ASMDMKTC---IDVNECDLNSNICMFGECENTKGSFICHCQL 602
Query: 594 XXXXXXXDSXXXXXXXXXXXXXX-QAGGTCLPSALPPGWACGCREGRTG-ALCELSLDLC 651
+ +CL +P + C CREG G + + D C
Sbjct: 603 GYSVKKGTTGCTDVDECEIGAHNCDMHASCLN--IPGSFKCSCREGWIGNGIKCIDRDEC 660
Query: 652 --GSSPCRNGGRCVGGSGWWMCECVAGWTGE--TCA 683
G+ C +CV G + C C G+TG+ TC+
Sbjct: 661 SNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS 696
Score = 77.8 bits (183), Expect = 2e-13
Identities = 116/464 (25%), Positives = 174/464 (37%), Gaps = 81/464 (17%)
Query: 263 CDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNP 318
C + G + +D+N C G CEN Y C C G+ SG +C +D
Sbjct: 4 CSSGVGITVDGRDINECALDPDICANGICENLR-GSYRCNCNSGYEPDASGRNCIDIDEC 62
Query: 319 CAPQ-PCAHGTCSLAGTTRGFTCTCDRGW---GGXXXXXXXXXXASGPCLHGASCRDHLD 374
+ C +G C T ++CTC G+ S PC++GA CR++L
Sbjct: 63 LVNRLLCDNGLC--RNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLG 119
Query: 375 GFTCECADG----WTGPACAEDVDECSGRSMTEGALGPCVNAAA----CNNTAG---GYS 423
F CEC+ G TG C + + ++ + +N A C T G G
Sbjct: 120 SFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSP 179
Query: 424 C-------AC---LAGWTGRDCETNVDDC---TGQCLHGATCIDLVDDFHCACAAGY--- 467
C AC LA G CE +V++C G C +G C++ FHC C G
Sbjct: 180 CERCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLTLD 237
Query: 468 -AGRTC-SLDVDDCAPRPCTNGGECV-DLLNAYR---CICPVGFS-GTNCEDDRDHCAGS 520
GR C + ++ C + + EC+ + +R C C VG + GT CE+
Sbjct: 238 GTGRVCLDIRMEQCYLK--WDEDECIHPVPGKFRMDACCCAVGAAWGTECEE-------- 287
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA--EGMCANGG 578
C T + + C G+ + D T ++ C GMC G
Sbjct: 288 -CPKPG---TKEYETLCPRGAGFANRG-------DVLTGRPFYKDINECKAFPGMCTY-G 335
Query: 579 TCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREG 638
C GS++ + G C+ + P + C C EG
Sbjct: 336 KCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNT--PGSFECECFEG 393
Query: 639 -RTGALCE---LSLDLCGSSP--CRNGGRCVGGSGWWMCECVAG 676
+G + + +D C +P CR GG CV G + C+C G
Sbjct: 394 YESGFMMMKNCMDIDGCERNPLLCR-GGTCVNTEGSFQCDCPLG 436
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/125 (33%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 460 HCACAAGYAGRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGF----SGTNCEDD 513
H C++G D+++CA P C NG C +L +YRC C G+ SG NC D
Sbjct: 1 HGLCSSGVGITVDGRDINECALDPDICANG-ICENLRGSYRCNCNSGYEPDASGRNCIDI 59
Query: 514 RDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAE 571
D C + C NG C Y C C PG+ + T+ D C ES C
Sbjct: 60 -DECLVNRLLCDNGL-CRNTPGSYSCTCPPGYVFRTETE-TCEDINEC-----ESNPCVN 111
Query: 572 GMCAN 576
G C N
Sbjct: 112 GACRN 116
>Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
1(Drosophila) protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein.
Length = 2725
Score = 119 bits (286), Expect = 6e-26
Identities = 88/285 (30%), Positives = 114/285 (40%), Gaps = 40/285 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGC-HPT---HGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKH 251
C GW+G C+ P +E C PT HG C G C C PG++GE+C + C H
Sbjct: 580 CRHGWKGPECDVP--EEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNH 636
Query: 252 GYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD 311
G C +C C T WGG+ C+ L C E C GT D C C ++G D
Sbjct: 637 GIC--VKGECHCSTGWGGVNCETPLPVC--QEQCSGHGTF---LLDAGVCSCDPKWTGSD 689
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C C + +HG CS RG C C+ GW G C C+D
Sbjct: 690 CST--ELCTMECGSHGVCS-----RGI-CQCEEGWVGPTCEERS---CHSHCTEHGQCKD 738
Query: 372 HLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
CEC+ GW G C A +D ++ +G G C C G+ C C G
Sbjct: 739 G----KCECSPGWEGDHCTIAHYLD-----AVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 789
Query: 430 WTGRDCETNVDDCTGQCL--HGATCIDLVDDFHCACAAGYAGRTC 472
W+G C ++ G L G D VD C + Y C
Sbjct: 790 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 109 bits (261), Expect = 6e-23
Identities = 97/348 (27%), Positives = 130/348 (37%), Gaps = 59/348 (16%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELC----S 241
G+ C G HC PG+ G +C + C C +G ++ G C CR GW+G C
Sbjct: 538 GNGECI-SGHCHCFPGFLGPDCARDSCPVLC-GGNGEYEK-GHCVCRHGWKGPECDVPEE 594
Query: 242 QCQPYPGC-KHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QC P C HG C C C + G +C+++ C C + G C
Sbjct: 595 QCID-PTCFGHGTC--IMGVCICVPGYKGEICEEE--DC-LDPMCSNHGICVKGE----- 643
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSL-AGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C+ G+ GV+CE C Q HGT L AG C+CD W G
Sbjct: 644 CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG-----VCSCDPKWTGSDCSTELCTME 698
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
G HG R C+C +GW GP C E C C C +
Sbjct: 699 CGS--HGVCSRG-----ICQCEEGWVGPTCEE--RSCHSH---------CTEHGQCKDG- 739
Query: 420 GGYSCACLAGWTGRDC------ETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCS 473
C C GW G C + D C G C C + +HC C G++G C+
Sbjct: 740 ---KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Query: 474 LDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
+ ++ N G+ C+ P +NC C GSP
Sbjct: 797 VVMEMLCGDNLDNDGD-----GLTDCVDPDCCQQSNCYIS-PLCQGSP 838
Score = 106 bits (254), Expect = 4e-22
Identities = 93/307 (30%), Positives = 112/307 (36%), Gaps = 51/307 (16%)
Query: 212 CKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGG 269
C C+ +G C G C C PG+ G C++ C G Y G C C W G
Sbjct: 532 CSTNCNG-NGECIS-GHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH---CVCRHGWKG 586
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCA-HGT 328
CD C C GTC C C G+ G CE D C C+ HG
Sbjct: 587 PECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICEEED--CLDPMCSNHGI 638
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C +G C C GWGG HG LD C C WTG
Sbjct: 639 C-----VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSD 689
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLH 448
C+ ++ C+ M G+ G C C C GW G CE C C
Sbjct: 690 CSTEL--CT---MECGSHGVCSRGI----------CQCEEGWVGPTCEER--SCHSHCTE 732
Query: 449 GATCIDLVDDFHCACAAGYAGRTCS----LD-VDDCAPRPCTNGGECVDLLNAYRCICPV 503
C D C C+ G+ G C+ LD V D P C G C N + C+C V
Sbjct: 733 HGQC----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 504 GFSGTNC 510
G+SGT C
Sbjct: 789 GWSGTGC 795
Score = 91.5 bits (217), Expect = 1e-17
Identities = 85/306 (27%), Positives = 118/306 (38%), Gaps = 57/306 (18%)
Query: 254 CNGS----SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
CNG+ S C C + G C +D C P GG E ++ C C G+ G
Sbjct: 536 CNGNGECISGHCHCFPGFLGPDCARDS--C----PVLCGGNGEY---EKGHCVCRHGWKG 586
Query: 310 VDCERVDNPCAPQPC-AHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGAS 368
+C+ + C C HGTC + C C G+ G C +
Sbjct: 587 PECDVPEEQCIDPTCFGHGTCIMG------VCICVPGYKGEICEEEDCLDPM--CSNHGI 638
Query: 369 CRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLA 428
C + G C C+ GW G C + C + G ++A C+ C
Sbjct: 639 C---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCS---------CDP 683
Query: 429 GWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGG 488
WTG DC T + CT +C C + C C G+ G TC + C CT G
Sbjct: 684 KWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CTEHG 734
Query: 489 ECVDLLNAYRCICPVGFSGTNC------EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
+C D +C C G+ G +C + RD C G GNG C Q+ ++C C G
Sbjct: 735 QCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR-CTLDQNGWHCVCQVG 789
Query: 543 WTGKNC 548
W+G C
Sbjct: 790 WSGTGC 795
Score = 87.0 bits (206), Expect = 3e-16
Identities = 85/288 (29%), Positives = 106/288 (36%), Gaps = 48/288 (16%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C C GF G DC R P C G C C GW G
Sbjct: 547 CHCFPGFLGPDCARDSCPVL--------CGGNGEYEKGHCVCRHGWKGPECDVPEEQCID 598
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP-CVNAAACNNTA 419
C +C + G C C G+ G C E+ +C L P C N C
Sbjct: 599 PTCFGHGTC---IMG-VCICVPGYKGEICEEE--DC---------LDPMCSNHGIC--VK 641
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G C C GW G +CET + C QC T L+D C+C + G CS ++ C
Sbjct: 642 G--ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--C 695
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
C + G C + C C G+ G CE+ H S C C D C C
Sbjct: 696 TME-CGSHGVCSRGI----CQCEEGWVGPTCEERSCH---SHCTEHGQC----KDGKCEC 743
Query: 540 APGWTGKNCTQRAARD--RKTCSVLVEESERCAEGMCANGGTCVREEG 585
+PGW G +CT D R C L + RC + NG CV + G
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT--LDQNGWHCVCQVG 789
Score = 82.6 bits (195), Expect = 6e-15
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 28/243 (11%)
Query: 164 LCQPNYYNTTCTTF-CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEK--PVCKEGCHPTH 220
+C P Y C C D ++ G+ HC GW G NCE PVC+E C
Sbjct: 613 ICVPGYKGEICEEEDCL--DPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHG 670
Query: 221 GRCDRPGDCDCRPGWRGELCSQ--CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY 278
G C C P W G CS C G HG C S C C+ W G C++
Sbjct: 671 TFLLDAGVCSCDPKWTGSDCSTELCTMECG-SHGVC--SRGICQCEEGWVGPTCEE--RS 725
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC------ERVDNPCAPQPCAHGTCSLA 332
C +H C G C++ C C+ G+ G C + V + C +G C+L
Sbjct: 726 CHSH--CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL- 777
Query: 333 GTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLH-GASCRDHLDGFTCECADGWTGPACAE 391
G+ C C GW G + G D +D C+ ++ + P C
Sbjct: 778 -DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQG 836
Query: 392 DVD 394
D
Sbjct: 837 SPD 839
Score = 77.4 bits (182), Expect = 2e-13
Identities = 65/269 (24%), Positives = 88/269 (32%), Gaps = 26/269 (9%)
Query: 424 CACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRP 483
C C G+ G DC D C C + HC C G+ G C + + C
Sbjct: 547 CHCFPGFLGPDCAR--DSCPVLCGGNGE----YEKGHCVCRHGWKGPECDVPEEQCIDPT 600
Query: 484 CTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW 543
C G C+ + CIC G+ G CE++ C C N C + CHC+ GW
Sbjct: 601 CFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGW 650
Query: 544 TGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXX 600
G NC ++ CS + ++ C+ G C E +
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 601 DSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELS--LDLCGSS-P-- 655
+ C C C G G C ++ LD P
Sbjct: 711 QCEEGWVGPTCEERSCHSH--CTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 768
Query: 656 CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
C GRC W C C GW+G C V
Sbjct: 769 CFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 67.3 bits (157), Expect = 3e-10
Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 51/247 (20%)
Query: 439 VDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
+DDC+ C CI HC C G+ G C+ D C P C GE
Sbjct: 529 MDDCSTNCNGNGECIS----GHCHCFPGFLGPDCARD--SC-PVLCGGNGE----YEKGH 577
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+C G+ G C+ + C C C C C PG+ G+ C
Sbjct: 578 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC---------- 623
Query: 559 CSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQA 618
E E C + MC+N G CV+ E
Sbjct: 624 ------EEEDCLDPMCSNHGICVKGE---------CHCSTGWGGVNCETPLPVCQEQCSG 668
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GT L A C C TG+ C S +LC + C + G C G +C+C GW
Sbjct: 669 HGTFLLDA----GVCSCDPKWTGSDC--STELC-TMECGSHGVCSRG----ICQCEEGWV 717
Query: 679 GETCAVR 685
G TC R
Sbjct: 718 GPTCEER 724
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G G CE L +C C G + +G +C C WTG C+ +
Sbjct: 644 CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 694
>AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein.
Length = 2450
Score = 118 bits (285), Expect = 8e-26
Identities = 93/344 (27%), Positives = 132/344 (38%), Gaps = 59/344 (17%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
G+ C G HC PG+ G +C + C C +G+ + G C C GW+G C P
Sbjct: 275 GNGECV-SGTCHCFPGFLGPDCSRAACPVLCSG-NGQYSK-GRCLCFSGWKGTECDV--P 329
Query: 246 YPGCKHGYCNGSS----WDCTCDTNWGGILCDQ-DL--NYCGTHEPCQHGGTCENTAPDQ 298
C C G C C++ + G C++ D C H C HG
Sbjct: 330 TTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGE--------- 380
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXX 358
C C+ G+ G +CE + C Q HGT +CTCD W G
Sbjct: 381 --CHCSPGWGGSNCEILKTMCPDQCSGHGTY----LQESGSCTCDPNWTGPDCSNEICSV 434
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
G HG C G TC C +GWTGPAC + C R C C +
Sbjct: 435 DCGS--HGV-CM----GGTCRCEEGWTGPACNQRA--CHPR---------CAEHGTCKDG 476
Query: 419 AGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
C C GW G C ++ C G C C + +HC C G+ G C + ++
Sbjct: 477 ----KCECSQGWNGEHC--TIEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMET 530
Query: 479 -CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSP 521
C G +D ++ C+ ++C+ ++ +C G P
Sbjct: 531 LCTDSKDNEGDGLIDCMDPDCCL------QSSCQ-NQPYCRGLP 567
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/253 (26%), Positives = 91/253 (35%), Gaps = 48/253 (18%)
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
C C G+ G +C+ C C G C + +C C+ G+ G
Sbjct: 315 CLCFSGWKGTECDVPTTQCIDPQCGGRGICIMG------SCACNSGYKGESCEEADCIDP 368
Query: 360 S----GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAAC 415
G C+HG C C+ GW G C C + C
Sbjct: 369 GCSNHGVCIHGE----------CHCSPGWGGSNCEILKTMCPDQ---------CSGHGTY 409
Query: 416 NNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLD 475
+G SC C WTG DC + C+ C C+ C C G+ G C+
Sbjct: 410 LQESG--SCTCDPNWTGPDCSNEI--CSVDCGSHGVCMGGT----CRCEEGWTGPACNQR 461
Query: 476 VDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDY 535
C PR C G C D +C C G++G +C + C G C + C Q+ +
Sbjct: 462 A--CHPR-CAEHGTCKD----GKCECSQGWNGEHCTIEG--CPGL-CNSNGRCTLDQNGW 511
Query: 536 YCHCAPGWTGKNC 548
+C C PGW G C
Sbjct: 512 HCVCQPGWRGAGC 524
Score = 79.8 bits (188), Expect = 4e-14
Identities = 64/265 (24%), Positives = 82/265 (30%), Gaps = 24/265 (9%)
Query: 423 SCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPR 482
+C C G+ G DC C C C C +G+ G C + C
Sbjct: 283 TCHCFPGFLGPDCSRAA--CPVLCSGNGQ----YSKGRCLCFSGWKGTECDVPTTQCIDP 336
Query: 483 PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C G C+ C C G+ G +CE+ C C N C + CHC+PG
Sbjct: 337 QCGGRGICI----MGSCACNSGYKGESCEEA--DCIDPGCSNHGVCIHGE----CHCSPG 386
Query: 543 WTGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXX 599
W G NC CS ++ES C G C E S
Sbjct: 387 WGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICS--VDCGSHGVCMG 444
Query: 600 XDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNG 659
C C C +G G C +++ C C +
Sbjct: 445 GTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHC--TIEGCPGL-CNSN 501
Query: 660 GRCVGGSGWWMCECVAGWTGETCAV 684
GRC W C C GW G C V
Sbjct: 502 GRCTLDQNGWHCVCQPGWRGAGCDV 526
Score = 72.5 bits (170), Expect = 7e-12
Identities = 55/197 (27%), Positives = 73/197 (37%), Gaps = 33/197 (16%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C C GW G C +C G G C+ SCAC +G+ G CE
Sbjct: 315 CLCFSGWKGTECDVPTTQCIDPQC--GGRGICIMG----------SCACNSGYKGESCE- 361
Query: 438 NVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAY 497
D C + CI C C+ G+ G C + C P C+ G L +
Sbjct: 362 EADCIDPGCSNHGVCIH----GECHCSPGWGGSNCEILKTMC-PDQCSGHGTY--LQESG 414
Query: 498 RCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C C ++G +C ++ CG+ C C C GWTG C QRA R
Sbjct: 415 SCTCDPNWTGPDCSNE---ICSVDCGSHGVCMGGT----CRCEEGWTGPACNQRACHPR- 466
Query: 558 TCSVLVEESERCAEGMC 574
C+ E C +G C
Sbjct: 467 -CA----EHGTCKDGKC 478
Score = 58.0 bits (134), Expect = 2e-07
Identities = 61/248 (24%), Positives = 85/248 (34%), Gaps = 51/248 (20%)
Query: 438 NVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAY 497
+V +C C C+ C C G+ G CS P C+ G+ +
Sbjct: 265 SVVECPRNCHGNGECVSGT----CHCFPGFLGPDCSRAA---CPVLCSGNGQ----YSKG 313
Query: 498 RCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
RC+C G+ GT C+ C CG C C C G+ G++C
Sbjct: 314 RCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGS----CACNSGYKGESC--------- 360
Query: 558 TCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQ 617
EE++ C + C+N G C+ G Q
Sbjct: 361 ------EEAD-CIDPGCSNHGVCIH--GECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQ 411
Query: 618 AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
G+C P W TG C S ++C S C + G C+GG+ C C GW
Sbjct: 412 ESGSC---TCDPNW--------TGPDC--SNEIC-SVDCGSHGVCMGGT----CRCEEGW 453
Query: 678 TGETCAVR 685
TG C R
Sbjct: 454 TGPACNQR 461
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 114 bits (274), Expect = 2e-24
Identities = 106/398 (26%), Positives = 156/398 (39%), Gaps = 60/398 (15%)
Query: 219 THGRCDRPGD---CDCRPGW----RGELC---SQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
+ GRC+ C C G+ G C +C C G+C + C+
Sbjct: 600 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 659
Query: 269 GILCDQDLNYCGTHEPCQHGGTCEN----TAPDQYFC-RCAEGFSGVD--CERVDNPCAP 321
G Q C + C + TC + +P Y C C EGF G + C VD P
Sbjct: 660 GYRMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 718
Query: 322 QPCAHGTCS-LAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCLHGASCRDHLDGF 376
CA+G CS L G+ + C+C +G+ C++G C++ F
Sbjct: 719 NVCANGDCSNLEGS---YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEGSF 774
Query: 377 TCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT-- 431
C C G+ A ED+DEC R + C + C NT G + C C G+
Sbjct: 775 RCTCGQGYQLSAAKDQCEDIDECQHRHL-------CAHGQ-CRNTEGSFQCVCDQGYRAS 826
Query: 432 --GRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCA-PR 482
G CE ++++C C G CI+ + C C G+ +TC D+++C P
Sbjct: 827 GLGDHCE-DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPG 883
Query: 483 PCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C GEC++ ++ C+C GFS G CED + + C + C + C
Sbjct: 884 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 943
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C G+ Q D C +L S C E C N
Sbjct: 944 CYQGFQAPQDGQGCV-DVNECELL---SGVCGEAFCEN 977
Score = 105 bits (251), Expect = 1e-21
Identities = 106/380 (27%), Positives = 151/380 (39%), Gaps = 62/380 (16%)
Query: 241 SQCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHGGTCENT 294
++C P C G+C TC G +Q D++ C + G CENT
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 295 APDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGWGGX 349
+ C C GF G +C VD P C G C T F C CD G+
Sbjct: 608 E-GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAFRCEYCDSGY--- 661
Query: 350 XXXXXXXXXASGPCLHGASCRDHL-----DGFTC-ECADGWTG--PACAEDVDECSGRSM 401
CL+ ++C D + C C +G+ G C DVDEC ++
Sbjct: 662 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNV 720
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT--GQCLHGATCIDL 455
C N C+N G Y C+C G+T + C ++D+C C++G C +
Sbjct: 721 -------CANGD-CSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQ-CKNT 770
Query: 456 VDDFHCACAAGY---AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS----GT 508
F C C GY A + D+D+C R G+C + +++C+C G+ G
Sbjct: 771 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 830
Query: 509 NCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CED + S C G TA S Y C C G+ D KTC + E E
Sbjct: 831 HCEDINECLEDKSVCQRGDCINTAGS-YDCTCPDGF--------QLDDNKTCQD-INECE 880
Query: 568 RCAEGMCANGGTCVREEGSW 587
G+C G C+ EGS+
Sbjct: 881 H--PGLCGPQGECLNTEGSF 898
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/228 (30%), Positives = 101/228 (44%), Gaps = 36/228 (15%)
Query: 376 FTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+TC C +G+ D+DEC+ + + C NT G + C C AG+
Sbjct: 569 YTCICYEGYRFSEQQRKCVDIDECT-------QVQHLCSQGRCENTEGSFLCICPAGFMA 621
Query: 433 RDCETN---VDDCTGQCLHG-ATCIDLVDDFHCA-CAAGY--AGRTCSLDVDDCA-PRPC 484
+ TN VD+C + G C++ V F C C +GY R D+D+C P C
Sbjct: 622 SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTC 681
Query: 485 TNGGECVDLLNAYRCI-CPVGFSGTNCED-DRDHCAG-SPCGNGAACYTAQSDYYCHCAP 541
+ +CV+ +Y+C+ C GF G N + D D C + C NG C + Y C C
Sbjct: 682 PDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK 739
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVREEGSWR 588
G+T D K C + + C +G +C NG C EGS+R
Sbjct: 740 GYT-------RTPDHKHC----RDIDECQQGNLCVNG-QCKNTEGSFR 775
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/442 (25%), Positives = 158/442 (35%), Gaps = 78/442 (17%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR----GELCS 241
Y+ TPD KHC D C++ +C G C T G C C G++ + C
Sbjct: 741 YTRTPD-HKHCR---DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCE 792
Query: 242 ---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGI-LCD--QDLNYCGTHEPCQHGGTCEN 293
+CQ C HG C + S+ C CD + L D +D+N C + G C N
Sbjct: 793 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 852
Query: 294 TAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWG-- 347
TA Y C C +GF D C+ ++ P C G C T F C C +G+
Sbjct: 853 TA-GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC--LNTEGSFHCVCQQGFSIS 909
Query: 348 --GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G + C C + F C C G+ P +D C + E
Sbjct: 910 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP---QDGQGCVDVNECELL 966
Query: 406 LGPCVNAAACNNTAGGYSCAC---------LAGW----TGRDCETNVD---DCTGQCLHG 449
G C A C N G + C C + G T D + +VD + +C +
Sbjct: 967 SGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1025
Query: 450 ATCIDLVDDF--------HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
L D+ C C +G AG + ++ C P E ++ +
Sbjct: 1026 LNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPC---PVLGTAEFTEMCPKGKGFV 1081
Query: 502 PVGFS----GTNCEDDRDHC---AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
P G S G D D C C NG C + Y C+C G T + +
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG-TYYDPVKLQCF 1139
Query: 555 DRKTCSVLVEESERCAEGMCAN 576
D C ++ C +G C N
Sbjct: 1140 DMDEC----QDPSSCIDGQCVN 1157
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C DG+ T DV+EC + + C NA C NT
Sbjct: 1304 CENGRCVRVQ-EGYTCDCLDGYHLDTAKMTCFDVNECDELN---NRMSLCKNAK-CINTD 1358
Query: 420 GGYSCACLAGWTGRD 434
G Y C CL G+ D
Sbjct: 1359 GSYKCLCLPGYVPSD 1373
Score = 38.7 bits (86), Expect = 0.10
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C GY T D+++C + GEC++ + +YRC C +GF
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 114 bits (274), Expect = 2e-24
Identities = 106/398 (26%), Positives = 156/398 (39%), Gaps = 60/398 (15%)
Query: 219 THGRCDRPGD---CDCRPGW----RGELC---SQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
+ GRC+ C C G+ G C +C C G+C + C+
Sbjct: 601 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 660
Query: 269 GILCDQDLNYCGTHEPCQHGGTCEN----TAPDQYFC-RCAEGFSGVD--CERVDNPCAP 321
G Q C + C + TC + +P Y C C EGF G + C VD P
Sbjct: 661 GYRMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 719
Query: 322 QPCAHGTCS-LAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCLHGASCRDHLDGF 376
CA+G CS L G+ + C+C +G+ C++G C++ F
Sbjct: 720 NVCANGDCSNLEGS---YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEGSF 775
Query: 377 TCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT-- 431
C C G+ A ED+DEC R + C + C NT G + C C G+
Sbjct: 776 RCTCGQGYQLSAAKDQCEDIDECQHRHL-------CAHGQ-CRNTEGSFQCVCDQGYRAS 827
Query: 432 --GRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCA-PR 482
G CE ++++C C G CI+ + C C G+ +TC D+++C P
Sbjct: 828 GLGDHCE-DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPG 884
Query: 483 PCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C GEC++ ++ C+C GFS G CED + + C + C + C
Sbjct: 885 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 944
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C G+ Q D C +L S C E C N
Sbjct: 945 CYQGFQAPQDGQGCV-DVNECELL---SGVCGEAFCEN 978
Score = 105 bits (251), Expect = 1e-21
Identities = 106/380 (27%), Positives = 151/380 (39%), Gaps = 62/380 (16%)
Query: 241 SQCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHGGTCENT 294
++C P C G+C TC G +Q D++ C + G CENT
Sbjct: 549 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 608
Query: 295 APDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGWGGX 349
+ C C GF G +C VD P C G C T F C CD G+
Sbjct: 609 E-GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAFRCEYCDSGY--- 662
Query: 350 XXXXXXXXXASGPCLHGASCRDHL-----DGFTC-ECADGWTG--PACAEDVDECSGRSM 401
CL+ ++C D + C C +G+ G C DVDEC ++
Sbjct: 663 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNV 721
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT--GQCLHGATCIDL 455
C N C+N G Y C+C G+T + C ++D+C C++G C +
Sbjct: 722 -------CANGD-CSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQ-CKNT 771
Query: 456 VDDFHCACAAGY---AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS----GT 508
F C C GY A + D+D+C R G+C + +++C+C G+ G
Sbjct: 772 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 831
Query: 509 NCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CED + S C G TA S Y C C G+ D KTC + E E
Sbjct: 832 HCEDINECLEDKSVCQRGDCINTAGS-YDCTCPDGF--------QLDDNKTCQD-INECE 881
Query: 568 RCAEGMCANGGTCVREEGSW 587
G+C G C+ EGS+
Sbjct: 882 H--PGLCGPQGECLNTEGSF 899
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/228 (30%), Positives = 101/228 (44%), Gaps = 36/228 (15%)
Query: 376 FTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+TC C +G+ D+DEC+ + + C NT G + C C AG+
Sbjct: 570 YTCICYEGYRFSEQQRKCVDIDECT-------QVQHLCSQGRCENTEGSFLCICPAGFMA 622
Query: 433 RDCETN---VDDCTGQCLHG-ATCIDLVDDFHCA-CAAGY--AGRTCSLDVDDCA-PRPC 484
+ TN VD+C + G C++ V F C C +GY R D+D+C P C
Sbjct: 623 SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTC 682
Query: 485 TNGGECVDLLNAYRCI-CPVGFSGTNCED-DRDHCAG-SPCGNGAACYTAQSDYYCHCAP 541
+ +CV+ +Y+C+ C GF G N + D D C + C NG C + Y C C
Sbjct: 683 PDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK 740
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVREEGSWR 588
G+T D K C + + C +G +C NG C EGS+R
Sbjct: 741 GYT-------RTPDHKHC----RDIDECQQGNLCVNG-QCKNTEGSFR 776
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/442 (25%), Positives = 158/442 (35%), Gaps = 78/442 (17%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR----GELCS 241
Y+ TPD KHC D C++ +C G C T G C C G++ + C
Sbjct: 742 YTRTPD-HKHCR---DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCE 793
Query: 242 ---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGI-LCD--QDLNYCGTHEPCQHGGTCEN 293
+CQ C HG C + S+ C CD + L D +D+N C + G C N
Sbjct: 794 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 853
Query: 294 TAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWG-- 347
TA Y C C +GF D C+ ++ P C G C T F C C +G+
Sbjct: 854 TA-GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC--LNTEGSFHCVCQQGFSIS 910
Query: 348 --GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G + C C + F C C G+ P +D C + E
Sbjct: 911 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP---QDGQGCVDVNECELL 967
Query: 406 LGPCVNAAACNNTAGGYSCAC---------LAGW----TGRDCETNVD---DCTGQCLHG 449
G C A C N G + C C + G T D + +VD + +C +
Sbjct: 968 SGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1026
Query: 450 ATCIDLVDDF--------HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
L D+ C C +G AG + ++ C P E ++ +
Sbjct: 1027 LNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPC---PVLGTAEFTEMCPKGKGFV 1082
Query: 502 PVGFS----GTNCEDDRDHC---AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
P G S G D D C C NG C + Y C+C G T + +
Sbjct: 1083 PAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG-TYYDPVKLQCF 1140
Query: 555 DRKTCSVLVEESERCAEGMCAN 576
D C ++ C +G C N
Sbjct: 1141 DMDEC----QDPSSCIDGQCVN 1158
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C DG+ T DV+EC + + C NA C NT
Sbjct: 1305 CENGRCVRVQ-EGYTCDCFDGYHLDTAKMTCVDVNECDELN---NRMSLCKNAK-CINTD 1359
Query: 420 GGYSCACLAGWTGRD 434
G Y C CL G+ D
Sbjct: 1360 GSYKCLCLPGYVPSD 1374
Score = 38.7 bits (86), Expect = 0.10
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C GY T D+++C + GEC++ + +YRC C +GF
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 114 bits (274), Expect = 2e-24
Identities = 106/398 (26%), Positives = 156/398 (39%), Gaps = 60/398 (15%)
Query: 219 THGRCDRPGD---CDCRPGW----RGELC---SQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
+ GRC+ C C G+ G C +C C G+C + C+
Sbjct: 600 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 659
Query: 269 GILCDQDLNYCGTHEPCQHGGTCEN----TAPDQYFC-RCAEGFSGVD--CERVDNPCAP 321
G Q C + C + TC + +P Y C C EGF G + C VD P
Sbjct: 660 GYRMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 718
Query: 322 QPCAHGTCS-LAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCLHGASCRDHLDGF 376
CA+G CS L G+ + C+C +G+ C++G C++ F
Sbjct: 719 NVCANGDCSNLEGS---YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEGSF 774
Query: 377 TCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT-- 431
C C G+ A ED+DEC R + C + C NT G + C C G+
Sbjct: 775 RCTCGQGYQLSAAKDQCEDIDECQHRHL-------CAHGQ-CRNTEGSFQCVCDQGYRAS 826
Query: 432 --GRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCA-PR 482
G CE ++++C C G CI+ + C C G+ +TC D+++C P
Sbjct: 827 GLGDHCE-DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPG 883
Query: 483 PCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C GEC++ ++ C+C GFS G CED + + C + C + C
Sbjct: 884 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 943
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C G+ Q D C +L S C E C N
Sbjct: 944 CYQGFQAPQDGQGCV-DVNECELL---SGVCGEAFCEN 977
Score = 105 bits (251), Expect = 1e-21
Identities = 106/380 (27%), Positives = 151/380 (39%), Gaps = 62/380 (16%)
Query: 241 SQCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHGGTCENT 294
++C P C G+C TC G +Q D++ C + G CENT
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 295 APDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGWGGX 349
+ C C GF G +C VD P C G C T F C CD G+
Sbjct: 608 E-GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAFRCEYCDSGY--- 661
Query: 350 XXXXXXXXXASGPCLHGASCRDHL-----DGFTC-ECADGWTG--PACAEDVDECSGRSM 401
CL+ ++C D + C C +G+ G C DVDEC ++
Sbjct: 662 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNV 720
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT--GQCLHGATCIDL 455
C N C+N G Y C+C G+T + C ++D+C C++G C +
Sbjct: 721 -------CANGD-CSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQ-CKNT 770
Query: 456 VDDFHCACAAGY---AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS----GT 508
F C C GY A + D+D+C R G+C + +++C+C G+ G
Sbjct: 771 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 830
Query: 509 NCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CED + S C G TA S Y C C G+ D KTC + E E
Sbjct: 831 HCEDINECLEDKSVCQRGDCINTAGS-YDCTCPDGF--------QLDDNKTCQD-INECE 880
Query: 568 RCAEGMCANGGTCVREEGSW 587
G+C G C+ EGS+
Sbjct: 881 H--PGLCGPQGECLNTEGSF 898
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/228 (30%), Positives = 101/228 (44%), Gaps = 36/228 (15%)
Query: 376 FTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+TC C +G+ D+DEC+ + + C NT G + C C AG+
Sbjct: 569 YTCICYEGYRFSEQQRKCVDIDECT-------QVQHLCSQGRCENTEGSFLCICPAGFMA 621
Query: 433 RDCETN---VDDCTGQCLHG-ATCIDLVDDFHCA-CAAGY--AGRTCSLDVDDCA-PRPC 484
+ TN VD+C + G C++ V F C C +GY R D+D+C P C
Sbjct: 622 SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTC 681
Query: 485 TNGGECVDLLNAYRCI-CPVGFSGTNCED-DRDHCAG-SPCGNGAACYTAQSDYYCHCAP 541
+ +CV+ +Y+C+ C GF G N + D D C + C NG C + Y C C
Sbjct: 682 PDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK 739
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVREEGSWR 588
G+T D K C + + C +G +C NG C EGS+R
Sbjct: 740 GYT-------RTPDHKHC----RDIDECQQGNLCVNG-QCKNTEGSFR 775
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/442 (25%), Positives = 158/442 (35%), Gaps = 78/442 (17%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR----GELCS 241
Y+ TPD KHC D C++ +C G C T G C C G++ + C
Sbjct: 741 YTRTPD-HKHCR---DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCE 792
Query: 242 ---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGI-LCD--QDLNYCGTHEPCQHGGTCEN 293
+CQ C HG C + S+ C CD + L D +D+N C + G C N
Sbjct: 793 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 852
Query: 294 TAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWG-- 347
TA Y C C +GF D C+ ++ P C G C T F C C +G+
Sbjct: 853 TA-GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC--LNTEGSFHCVCQQGFSIS 909
Query: 348 --GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G + C C + F C C G+ P +D C + E
Sbjct: 910 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP---QDGQGCVDVNECELL 966
Query: 406 LGPCVNAAACNNTAGGYSCAC---------LAGW----TGRDCETNVD---DCTGQCLHG 449
G C A C N G + C C + G T D + +VD + +C +
Sbjct: 967 SGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1025
Query: 450 ATCIDLVDDF--------HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
L D+ C C +G AG + ++ C P E ++ +
Sbjct: 1026 LNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPC---PVLGTAEFTEMCPKGKGFV 1081
Query: 502 PVGFS----GTNCEDDRDHC---AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
P G S G D D C C NG C + Y C+C G T + +
Sbjct: 1082 PAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG-TYYDPVKLQCF 1139
Query: 555 DRKTCSVLVEESERCAEGMCAN 576
D C ++ C +G C N
Sbjct: 1140 DMDEC----QDPSSCIDGQCVN 1157
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C DG+ T DV+EC + + C NA C NT
Sbjct: 1304 CENGRCVRVQ-EGYTCDCLDGYHLDTAKMTCVDVNECDELN---NRMSLCKNAK-CINTD 1358
Query: 420 GGYSCACLAGWTGRD 434
G Y C CL G+ D
Sbjct: 1359 GSYKCLCLPGYVPSD 1373
Score = 38.7 bits (86), Expect = 0.10
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C GY T D+++C + GEC++ + +YRC C +GF
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 114 bits (274), Expect = 2e-24
Identities = 106/398 (26%), Positives = 156/398 (39%), Gaps = 60/398 (15%)
Query: 219 THGRCDRPGD---CDCRPGW----RGELC---SQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
+ GRC+ C C G+ G C +C C G+C + C+
Sbjct: 54 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 113
Query: 269 GILCDQDLNYCGTHEPCQHGGTCEN----TAPDQYFC-RCAEGFSGVD--CERVDNPCAP 321
G Q C + C + TC + +P Y C C EGF G + C VD P
Sbjct: 114 GYRMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 172
Query: 322 QPCAHGTCS-LAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCLHGASCRDHLDGF 376
CA+G CS L G+ + C+C +G+ C++G C++ F
Sbjct: 173 NVCANGDCSNLEGS---YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEGSF 228
Query: 377 TCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT-- 431
C C G+ A ED+DEC R + C + C NT G + C C G+
Sbjct: 229 RCTCGQGYQLSAAKDQCEDIDECQHRHL-------CAHGQ-CRNTEGSFQCVCDQGYRAS 280
Query: 432 --GRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCA-PR 482
G CE ++++C C G CI+ + C C G+ +TC D+++C P
Sbjct: 281 GLGDHCE-DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPG 337
Query: 483 PCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C GEC++ ++ C+C GFS G CED + + C + C + C
Sbjct: 338 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 397
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C G+ Q D C +L S C E C N
Sbjct: 398 CYQGFQAPQDGQGCV-DVNECELL---SGVCGEAFCEN 431
Score = 105 bits (251), Expect = 1e-21
Identities = 106/380 (27%), Positives = 151/380 (39%), Gaps = 62/380 (16%)
Query: 241 SQCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHGGTCENT 294
++C P C G+C TC G +Q D++ C + G CENT
Sbjct: 2 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 61
Query: 295 APDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGWGGX 349
+ C C GF G +C VD P C G C T F C CD G+
Sbjct: 62 E-GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAFRCEYCDSGY--- 115
Query: 350 XXXXXXXXXASGPCLHGASCRDHL-----DGFTC-ECADGWTG--PACAEDVDECSGRSM 401
CL+ ++C D + C C +G+ G C DVDEC ++
Sbjct: 116 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNV 174
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT--GQCLHGATCIDL 455
C N C+N G Y C+C G+T + C ++D+C C++G C +
Sbjct: 175 -------CANGD-CSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQ-CKNT 224
Query: 456 VDDFHCACAAGY---AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS----GT 508
F C C GY A + D+D+C R G+C + +++C+C G+ G
Sbjct: 225 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 284
Query: 509 NCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CED + S C G TA S Y C C G+ D KTC + E E
Sbjct: 285 HCEDINECLEDKSVCQRGDCINTAGS-YDCTCPDGF--------QLDDNKTCQD-INECE 334
Query: 568 RCAEGMCANGGTCVREEGSW 587
G+C G C+ EGS+
Sbjct: 335 H--PGLCGPQGECLNTEGSF 352
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/228 (30%), Positives = 101/228 (44%), Gaps = 36/228 (15%)
Query: 376 FTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+TC C +G+ D+DEC+ + + C NT G + C C AG+
Sbjct: 23 YTCICYEGYRFSEQQRKCVDIDECT-------QVQHLCSQGRCENTEGSFLCICPAGFMA 75
Query: 433 RDCETN---VDDCTGQCLHG-ATCIDLVDDFHCA-CAAGY--AGRTCSLDVDDCA-PRPC 484
+ TN VD+C + G C++ V F C C +GY R D+D+C P C
Sbjct: 76 SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTC 135
Query: 485 TNGGECVDLLNAYRCI-CPVGFSGTNCED-DRDHCAG-SPCGNGAACYTAQSDYYCHCAP 541
+ +CV+ +Y+C+ C GF G N + D D C + C NG C + Y C C
Sbjct: 136 PDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK 193
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVREEGSWR 588
G+T D K C + + C +G +C NG C EGS+R
Sbjct: 194 GYT-------RTPDHKHC----RDIDECQQGNLCVNG-QCKNTEGSFR 229
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/443 (25%), Positives = 156/443 (35%), Gaps = 80/443 (18%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR----GELCS 241
Y+ TPD KHC D C++ +C G C T G C C G++ + C
Sbjct: 195 YTRTPD-HKHCR---DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCE 246
Query: 242 ---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGI-LCD--QDLNYCGTHEPCQHGGTCEN 293
+CQ C HG C + S+ C CD + L D +D+N C + G C N
Sbjct: 247 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 306
Query: 294 TAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWG-- 347
TA Y C C +GF D C+ ++ P C G C T F C C +G+
Sbjct: 307 TA-GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC--LNTEGSFHCVCQQGFSIS 363
Query: 348 --GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G + C C + F C C G+ P +D C + E
Sbjct: 364 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP---QDGQGCVDVNECELL 420
Query: 406 LGPCVNAAACNNTAGGYSCAC---------LAGW----TGRDCETNVD---DCTGQCLHG 449
G C A C N G + C C + G T D + +VD + +C +
Sbjct: 421 SGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 479
Query: 450 ATCIDLVDDF--------HCACAAGYA-GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
L D+ C C +G G C + P P E ++ +
Sbjct: 480 LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEI-----FPCPVLGTAEFTEMCPKGKGF 534
Query: 501 CPVGFS----GTNCEDDRDHC---AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
P G S G D D C C NG C + Y C+C G T + +
Sbjct: 535 VPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG-TYYDPVKLQC 592
Query: 554 RDRKTCSVLVEESERCAEGMCAN 576
D C ++ C +G C N
Sbjct: 593 FDMDEC----QDPSSCIDGQCVN 611
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 114 bits (274), Expect = 2e-24
Identities = 106/398 (26%), Positives = 156/398 (39%), Gaps = 60/398 (15%)
Query: 219 THGRCDRPGD---CDCRPGW----RGELC---SQCQPYPGCKHGYCNGSSWDCTCDTNWG 268
+ GRC+ C C G+ G C +C C G+C + C+
Sbjct: 554 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 613
Query: 269 GILCDQDLNYCGTHEPCQHGGTCEN----TAPDQYFC-RCAEGFSGVD--CERVDNPCAP 321
G Q C + C + TC + +P Y C C EGF G + C VD P
Sbjct: 614 GYRMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 672
Query: 322 QPCAHGTCS-LAGTTRGFTCTCDRGWGGXXXXXXXXXX----ASGPCLHGASCRDHLDGF 376
CA+G CS L G+ + C+C +G+ C++G C++ F
Sbjct: 673 NVCANGDCSNLEGS---YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEGSF 728
Query: 377 TCECADGWTGPAC---AEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT-- 431
C C G+ A ED+DEC R + C + C NT G + C C G+
Sbjct: 729 RCTCGQGYQLSAAKDQCEDIDECQHRHL-------CAHGQ-CRNTEGSFQCVCDQGYRAS 780
Query: 432 --GRDCETNVDDCTGQ---CLHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCA-PR 482
G CE ++++C C G CI+ + C C G+ +TC D+++C P
Sbjct: 781 GLGDHCE-DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPG 837
Query: 483 PCTNGGECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C GEC++ ++ C+C GFS G CED + + C + C + C
Sbjct: 838 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 897
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
C G+ Q D C +L S C E C N
Sbjct: 898 CYQGFQAPQDGQGCV-DVNECELL---SGVCGEAFCEN 931
Score = 105 bits (251), Expect = 1e-21
Identities = 106/380 (27%), Positives = 151/380 (39%), Gaps = 62/380 (16%)
Query: 241 SQCQPYPG-CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHGGTCENT 294
++C P C G+C TC G +Q D++ C + G CENT
Sbjct: 502 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 561
Query: 295 APDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCT-CDRGWGGX 349
+ C C GF G +C VD P C G C T F C CD G+
Sbjct: 562 E-GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAFRCEYCDSGY--- 615
Query: 350 XXXXXXXXXASGPCLHGASCRDHL-----DGFTC-ECADGWTG--PACAEDVDECSGRSM 401
CL+ ++C D + C C +G+ G C DVDEC ++
Sbjct: 616 RMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNV 674
Query: 402 TEGALGPCVNAAACNNTAGGYSCACLAGWTG----RDCETNVDDCT--GQCLHGATCIDL 455
C N C+N G Y C+C G+T + C ++D+C C++G C +
Sbjct: 675 -------CANGD-CSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQ-CKNT 724
Query: 456 VDDFHCACAAGY---AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFS----GT 508
F C C GY A + D+D+C R G+C + +++C+C G+ G
Sbjct: 725 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 784
Query: 509 NCEDDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+CED + S C G TA S Y C C G+ D KTC + E E
Sbjct: 785 HCEDINECLEDKSVCQRGDCINTAGS-YDCTCPDGF--------QLDDNKTCQD-INECE 834
Query: 568 RCAEGMCANGGTCVREEGSW 587
G+C G C+ EGS+
Sbjct: 835 H--PGLCGPQGECLNTEGSF 852
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/228 (30%), Positives = 101/228 (44%), Gaps = 36/228 (15%)
Query: 376 FTCECADGWTGPACAE---DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTG 432
+TC C +G+ D+DEC+ + + C NT G + C C AG+
Sbjct: 523 YTCICYEGYRFSEQQRKCVDIDECT-------QVQHLCSQGRCENTEGSFLCICPAGFMA 575
Query: 433 RDCETN---VDDCTGQCLHG-ATCIDLVDDFHCA-CAAGY--AGRTCSLDVDDCA-PRPC 484
+ TN VD+C + G C++ V F C C +GY R D+D+C P C
Sbjct: 576 SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTC 635
Query: 485 TNGGECVDLLNAYRCI-CPVGFSGTNCED-DRDHCAG-SPCGNGAACYTAQSDYYCHCAP 541
+ +CV+ +Y+C+ C GF G N + D D C + C NG C + Y C C
Sbjct: 636 PDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK 693
Query: 542 GWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCANGGTCVREEGSWR 588
G+T D K C + + C +G +C NG C EGS+R
Sbjct: 694 GYT-------RTPDHKHC----RDIDECQQGNLCVNG-QCKNTEGSFR 729
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/442 (25%), Positives = 158/442 (35%), Gaps = 78/442 (17%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEKP-VCKEG-CHPTHGRCDRPGDCDCRPGWR----GELCS 241
Y+ TPD KHC D C++ +C G C T G C C G++ + C
Sbjct: 695 YTRTPD-HKHCR---DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCE 746
Query: 242 ---QCQPYPGCKHGYCNGS--SWDCTCDTNWGGI-LCD--QDLNYCGTHEPCQHGGTCEN 293
+CQ C HG C + S+ C CD + L D +D+N C + G C N
Sbjct: 747 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 806
Query: 294 TAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWG-- 347
TA Y C C +GF D C+ ++ P C G C T F C C +G+
Sbjct: 807 TA-GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC--LNTEGSFHCVCQQGFSIS 863
Query: 348 --GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
G + C C + F C C G+ P +D C + E
Sbjct: 864 ADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP---QDGQGCVDVNECELL 920
Query: 406 LGPCVNAAACNNTAGGYSCAC---------LAGW----TGRDCETNVD---DCTGQCLHG 449
G C A C N G + C C + G T D + +VD + +C +
Sbjct: 921 SGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 979
Query: 450 ATCIDLVDDF--------HCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
L D+ C C +G AG + ++ C P E ++ +
Sbjct: 980 LNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPC---PVLGTAEFTEMCPKGKGFV 1035
Query: 502 PVGFS----GTNCEDDRDHC---AGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAAR 554
P G S G D D C C NG C + Y C+C G T + +
Sbjct: 1036 PAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG-TYYDPVKLQCF 1093
Query: 555 DRKTCSVLVEESERCAEGMCAN 576
D C ++ C +G C N
Sbjct: 1094 DMDEC----QDPSSCIDGQCVN 1111
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 363 CLHGASCRDHLDGFTCECADGW---TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C +G R +G+TC+C DG+ T DV+EC + + C NA C NT
Sbjct: 1258 CENGRCVRVQ-EGYTCDCFDGYHLDTAKMTCVDVNECDELN---NRMSLCKNAK-CINTD 1312
Query: 420 GGYSCACLAGWTGRD 434
G Y C CL G+ D
Sbjct: 1313 GSYKCLCLPGYVPSD 1327
Score = 38.7 bits (86), Expect = 0.10
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 463 CAAGY--AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C GY T D+++C + GEC++ + +YRC C +GF
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 336
>BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 619
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 619
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 619
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 594
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multiple
11 protein.
Length = 619
Score = 112 bits (269), Expect = 7e-24
Identities = 75/285 (26%), Positives = 112/285 (39%), Gaps = 23/285 (8%)
Query: 238 ELCSQCQPYPGCK-HGYCNGSSWD----CTCDTNWGGILCDQDLNYCGTHEPCQHGGTC- 291
+ C + C HG C +W C C + G C Q+L+ C + +PC++ G+C
Sbjct: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
Query: 292 ---ENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
EN Y C C F+G +C + C P C HG CS T+ F C CD + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI-TSNSFICECDEQFSG 288
Query: 349 XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGP 408
S C + +T EC G + DV E S L P
Sbjct: 289 PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS--------LVP 340
Query: 409 CVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCL-HGATCIDLVDDFHCACAAGY 467
C N C + C C +T C++ C L + ATC D+ C+C +G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 468 AGRTCSLDVDDC--APRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ C +D C C N C +++ ++ +C G + C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Score = 101 bits (242), Expect = 1e-20
Identities = 63/250 (25%), Positives = 99/250 (39%), Gaps = 16/250 (6%)
Query: 326 HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC---RDHLD--GFTCEC 380
HG C ++ ++C C + G PC + SC R++ D + C C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKRENWDEQAYECVC 244
Query: 381 ADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVD 440
+TG C+E + +C C + N T+ + C C ++G CE +
Sbjct: 245 HPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 441 DCTGQCL-HGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRC 499
C C + + C G + + DV + + PC NG +C+ + N C
Sbjct: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
Query: 500 ICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTC 559
IC F+ C+ + C P N A C + DY C C G+T KNC ++A K
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC-EKAIDHCKLL 415
Query: 560 SVLVEESERC 569
S+ E C
Sbjct: 416 SINCLNEEWC 425
Score = 83.8 bits (198), Expect = 3e-15
Identities = 64/255 (25%), Positives = 102/255 (40%), Gaps = 26/255 (10%)
Query: 197 HCLPGWQGDNCEK-PVCKEGCHPTHGRC--------DRPGDCDCRPGWRGELCS----QC 243
HC P + G C++ C +G C ++ +C C P + G+ CS QC
Sbjct: 201 HCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC 260
Query: 244 QPYPGCKHGYCN---GSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
QP+ C HG C+ +S+ C CD + G C+ C + + G C N++ Y
Sbjct: 261 QPHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKR-GICPNSS-SAYT 317
Query: 301 CRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS 360
C +G S + E + + PC +GT + + C C + S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIK-ISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 361 GPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
P + A+C+ + C C G+T C + +D C S+ C+N C N G
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN------CLNEEWCFNIIG 430
Query: 421 GYSCACLAGWTGRDC 435
+ C+ G T C
Sbjct: 431 RFKYVCIPGCTKNPC 445
Score = 69.7 bits (163), Expect = 5e-11
Identities = 53/229 (23%), Positives = 82/229 (35%), Gaps = 26/229 (11%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLN-----AYRCICPVGFSGTNCEDD 513
+ C C ++G+ C ++D C+ +PC N G C++ AY C+C F+G NC +
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 514 RDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM 573
C C +G + + C C ++G C A K C L+ G+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA----KPCVSLLFWKR----GI 308
Query: 574 CANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWAC 633
C N + E Q G C+ + C
Sbjct: 309 CPNSSSAYTYECP----------KGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMC 356
Query: 634 GCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C T LC+ C S P RN C + C C++G+T + C
Sbjct: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVG-GSGW----WMCECV 674
G CL A ++C C+ +G C+ LD C PC+N G C+ W + C C
Sbjct: 187 GKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
Query: 675 AGWTGETCA 683
+TG+ C+
Sbjct: 246 PPFTGKNCS 254
>U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged
protein.
Length = 263
Score = 111 bits (267), Expect = 1e-23
Identities = 49/136 (36%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
C +G TC+ + F C C G+ G C+ + +DC+P PC N G CVD N YRC C GF
Sbjct: 11 CHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGF 70
Query: 506 SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEE 565
+G +C + + C SPC GA C + Y C C PG +G C + + R T ++ +
Sbjct: 71 AGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPD 130
Query: 566 SER----CAEGMCANG 577
+ C C NG
Sbjct: 131 GAKWDDDCNTCQCLNG 146
Score = 91.5 bits (217), Expect = 1e-17
Identities = 63/202 (31%), Positives = 87/202 (43%), Gaps = 37/202 (18%)
Query: 316 DNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLD 374
++ C P PC +G TC + G + FTC C GW G + PC + +C D +
Sbjct: 3 NSSCLPNPCHNGGTCVVNGES--FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDN 60
Query: 375 GFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
+ CECA G+ GP C +++EC PC A C + GY C C G +G
Sbjct: 61 WYRCECAPGFAGPDCRININECQS--------SPCAFGATCVDEINGYRCVCPPGHSGAK 112
Query: 435 CET----------NV--------DDC-TGQCLHGATCIDLV--DDFHCACAAGY----AG 469
C+ +V DDC T QCL+G V C G+ +G
Sbjct: 113 CQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSG 172
Query: 470 RTCSLDVDD-CAPRPCTNGGEC 490
++C +DD C PCT GEC
Sbjct: 173 QSCIPILDDQCFVHPCTGVGEC 194
Score = 88.2 bits (209), Expect = 1e-16
Identities = 54/149 (36%), Positives = 65/149 (43%), Gaps = 12/149 (8%)
Query: 241 SQCQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQ 298
S C P P G C NG S+ C C W G +C Q+ N C H PC + GTC + +
Sbjct: 4 SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPH-PCYNSGTCVD-GDNW 61
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
Y C CA GF+G DC N C PCA G TC G+ C C G G
Sbjct: 62 YRCECAPGFAGPDCRININECQSSPCAFGATC--VDEINGYRCVCPPGHSGAKCQEVSGR 119
Query: 358 --XASGPCL-HGASCRDHLDGFTCECADG 383
G + GA D D TC+C +G
Sbjct: 120 PCITMGSVIPDGAKWDD--DCNTCQCLNG 146
Score = 77.0 bits (181), Expect = 3e-13
Identities = 37/110 (33%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCH 538
C P PC NGG CV ++ C+C G+ G C + + C+ PC N C + Y C
Sbjct: 6 CLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCE 65
Query: 539 CAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
CAPG+ G +C + + E C CA G TCV E +R
Sbjct: 66 CAPGFAGPDCR-----------ININE---CQSSPCAFGATCVDEINGYR 101
Score = 74.1 bits (174), Expect = 2e-12
Identities = 49/184 (26%), Positives = 71/184 (38%), Gaps = 37/184 (20%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GGTC+ + + C C+EG G +C + + C PC N G CV G W+ CEC G+
Sbjct: 14 GGTCVVNG--ESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA 71
Query: 679 GETCAVRVSXXXXXXXXXXXXXXXXXXXXXXXSSTRCLCPAPPQRAARRCLETVAGLEAE 738
G C + ++ + RC+C PP + +C E
Sbjct: 72 GPDCRININ------ECQSSPCAFGATCVDEINGYRCVC--PPGHSGAKCQE-------- 115
Query: 739 GDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWW-WGCNACWCSGGVPTCTRLWCGL 797
V RP +G + +G W CN C C G C+++WCG
Sbjct: 116 -------------VSGRPCITMGS-----VIPDGAKWDDDCNTCQCLNGRIACSKVWCGP 157
Query: 798 PDCL 801
CL
Sbjct: 158 RPCL 161
Score = 68.5 bits (160), Expect = 1e-10
Identities = 40/114 (35%), Positives = 54/114 (47%), Gaps = 13/114 (11%)
Query: 216 CHPTHGRCDRPGD---CDCRPGWRGELCSQ----CQPYPGCKHGYC-NGSSW-DCTCDTN 266
CH G C G+ C C+ GW G +C+Q C P+P G C +G +W C C
Sbjct: 11 CH-NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 69
Query: 267 WGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVD-NPC 319
+ G C ++N C + PC G TC + + Y C C G SG C+ V PC
Sbjct: 70 FAGPDCRININECQS-SPCAFGATCVDEI-NGYRCVCPPGHSGAKCQEVSGRPC 121
Score = 39.9 bits (89), Expect = 0.044
Identities = 15/33 (45%), Positives = 17/33 (51%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
C +PC NGG CV + C C GW G CA
Sbjct: 6 CLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 38
>AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA
sequence from clone RP11-307F22 on chromosome 6. ).
Length = 186
Score = 111 bits (267), Expect = 1e-23
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 11/158 (6%)
Query: 372 HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+L+GF TG C ++DEC ++E PC++ C + Y+C C +G+
Sbjct: 24 YLNGFMFCLVCSNTGINCEINLDEC----LSE----PCLHDGVCIDGINHYTCDCKSGFF 75
Query: 432 GRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G CETN +DC + CLHG C +L++++ C+C A C + ++DC PC N G C
Sbjct: 76 GTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFC 134
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC 528
+ + CICP G++G CE D+CA P N C
Sbjct: 135 QKSAHGFTCICPRGYTGAYCEKSIDNCA-EPELNSVIC 171
Score = 106 bits (254), Expect = 4e-22
Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 11/166 (6%)
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
G+ + TG +CE N+D+C + CLH CID ++ + C C +G+ G C + +DC
Sbjct: 27 GFMFCLVCSNTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC 86
Query: 480 APRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHC 539
PC +G C +L+N Y C C + T C+ + C PC N C + + C C
Sbjct: 87 LSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCIC 145
Query: 540 APGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
G+TG C + C+ E E +C NGG CV G
Sbjct: 146 PRGYTGAYC----EKSIDNCA----EPE-LNSVICLNGGICVDGPG 182
Score = 97.1 bits (231), Expect = 3e-19
Identities = 52/168 (30%), Positives = 71/168 (42%), Gaps = 9/168 (5%)
Query: 253 YCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
Y NG + C GI C+ +L+ C EPC H G C + + Y C C GF G C
Sbjct: 24 YLNGFMFCLVCSNT--GINCEINLDEC-LSEPCLHDGVCIDGI-NHYTCDCKSGFFGTHC 79
Query: 313 ERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH 372
E N C PC HG C+ + C+CD S PC++ C+
Sbjct: 80 ETNANDCLSNPCLHGRCT--ELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKS 137
Query: 373 LDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
GFTC C G+TG C + +D C+ + C+N C + G
Sbjct: 138 AHGFTCICPRGYTGAYCEKSIDNCAEPELNSVI---CLNGGICVDGPG 182
Score = 91.5 bits (217), Expect = 1e-17
Identities = 45/139 (32%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLH C D ++ +TC+C G+ G C + ++C PC++ C
Sbjct: 50 SEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS--------NPCLH-GRCTELI 100
Query: 420 GGYSCACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDD 478
Y C+C A T C+ ++DCT C++ C F C C GY G C +D+
Sbjct: 101 NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDN 160
Query: 479 CAPRP-----CTNGGECVD 492
CA C NGG CVD
Sbjct: 161 CAEPELNSVICLNGGICVD 179
Score = 47.2 bits (107), Expect = 3e-04
Identities = 18/43 (41%), Positives = 26/43 (60%)
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
TG CE++LD C S PC + G C+ G + C+C +G+ G C
Sbjct: 37 TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 79
Score = 43.2 bits (97), Expect = 0.005
Identities = 17/52 (32%), Positives = 25/52 (48%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
+ C C T C++ ++ C S PC N G C + + C C G+TG C
Sbjct: 103 YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYC 154
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/59 (30%), Positives = 25/59 (42%)
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
LN + +G NCE + D C PC + C + Y C C G+ G +C A
Sbjct: 25 LNGFMFCLVCSNTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNA 83
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 7/53 (13%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLC-----GSSPCRNGGRCVGGSG 667
G C SA G+ C C G TGA CE S+D C S C NGG CV G G
Sbjct: 132 GFCQKSA--HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPG 182
Score = 41.9 bits (94), Expect = 0.011
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
+ C C+ G G CE + + C S+PC + GRC + C C A T C ++++
Sbjct: 66 YTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKIN 121
>AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens
cDNA FLJ44823 fis, clone BRACE3046466, weakly similar
to Crumbs protein homolog 1 precursor. ).
Length = 952
Score = 109 bits (261), Expect = 6e-23
Identities = 55/157 (35%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 359 ASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
A PCLH +CRD D F C C GW GP C VD C PC +
Sbjct: 729 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS--------APCARGRCHTHP 780
Query: 419 AGGYSCACLAGWTGRDCETNVD--DCTGQ--CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
G + C C G+ G C V +C+ CL G+ C +C+C G AG+ C +
Sbjct: 781 DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAANCSCLEGLAGQRCQV 840
Query: 475 DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
C PC NGG C CIC FSG CE
Sbjct: 841 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 877
Score = 91.1 bits (216), Expect = 2e-17
Identities = 47/148 (31%), Positives = 64/148 (43%), Gaps = 4/148 (2%)
Query: 405 ALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCAC 463
A PC++ AC + ++CAC GW G CE +VD C + C G F C C
Sbjct: 729 APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRC 788
Query: 464 AAGYAGRTCSLDVD--DCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
G+ G C L V +C+ C +G C A C C G +G C+ C +
Sbjct: 789 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAANCSCLEGLAGQRCQVPTLPCEAN 848
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNC 548
PC NG C A C C ++G+ C
Sbjct: 849 PCLNGGTCRAAGGVSECICNARFSGQFC 876
Score = 87.8 bits (208), Expect = 2e-16
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Query: 319 CAPQPCAH-GTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDG-F 376
CAP PC H G C F C C GW G S PC G C H DG F
Sbjct: 728 CAPSPCLHDGACR--DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRF 784
Query: 377 TCECADGWTGPACAEDVD--ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
C C G+ GP C V ECS ++T C++ + C + +C+CL G G+
Sbjct: 785 ECRCPPGFGGPRCRLPVPSKECS-LNVT------CLDGSPCEGRSPAANCSCLEGLAGQR 837
Query: 435 CETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSL 474
C+ C CL+G TC C C A ++G+ C +
Sbjct: 838 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 878
Score = 84.6 bits (200), Expect = 2e-15
Identities = 47/156 (30%), Positives = 59/156 (37%), Gaps = 13/156 (8%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCD 343
PC H G C + D + C C G+ G CE +PC PCA G C R F C C
Sbjct: 732 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR-FECRCP 789
Query: 344 RGWGG---XXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRS 400
G+GG + CL G+ C C C +G G C C
Sbjct: 790 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAANCSCLEGLAGQRCQVPTLPCEA-- 847
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC+N C G C C A ++G+ CE
Sbjct: 848 ------NPCLNGGTCRAAGGVSECICNARFSGQFCE 877
Score = 73.3 bits (172), Expect = 4e-12
Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAA 527
AG TC DVD+C PC +GG C D + Y C CP + G +C C G C A
Sbjct: 19 AGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAAT 78
Query: 528 CY----TAQSDYYCHCAPGWTGKNCTQ 550
C + Y CHC PG G C Q
Sbjct: 79 CIPIFESGVHSYVCHCPPGAHGPFCGQ 105
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGF 505
CLH C DL D F CAC G+ G C VD C PC G + C CP GF
Sbjct: 733 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 792
Query: 506 SGTNCE---DDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVL 562
G C ++ C +G+ C C C G G+ C
Sbjct: 793 GGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAANCSCLEGLAGQRCQVPTLP-------- 844
Query: 563 VEESERCAEGMCANGGTC 580
C C NGGTC
Sbjct: 845 ------CEANPCLNGGTC 856
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/86 (39%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT-AQSDYYC 537
CAP PC + G C DL +A+ C C G+ G CE D C +PC G C+T + C
Sbjct: 728 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 786
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLV 563
C PG+ G C R K CS+ V
Sbjct: 787 RCPPGFGGPRC--RLPVPSKECSLNV 810
Score = 69.3 bits (162), Expect = 6e-11
Identities = 47/152 (30%), Positives = 59/152 (38%), Gaps = 17/152 (11%)
Query: 210 PVCKEGCHPTHGRCDRPGD---CDCRPGWRGELC----SQCQPYPGCKHGYCN---GSSW 259
PVC G C D C C PGW G C C P C G C+ +
Sbjct: 726 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 784
Query: 260 DCTCDTNWGGILCDQDL--NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDN 317
+C C +GG C + C + C G CE +P C C EG +G C+
Sbjct: 785 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAAN-CSCLEGLAGQRCQVPTL 843
Query: 318 PCAPQPCAH-GTCSLAGTTRGFTCTCDRGWGG 348
PC PC + GTC AG C C+ + G
Sbjct: 844 PCEANPCLNGGTCRAAGGVS--ECICNARFSG 873
Score = 68.5 bits (160), Expect = 1e-10
Identities = 35/92 (38%), Positives = 42/92 (45%), Gaps = 13/92 (14%)
Query: 386 GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQ 445
GP C EDVDEC PC++ C++T GY C C W GRDC + C G
Sbjct: 20 GPTCEEDVDECLS--------DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 71
Query: 446 -CLHGATCIDL----VDDFHCACAAGYAGRTC 472
C ATCI + V + C C G G C
Sbjct: 72 TCPLAATCIPIFESGVHSYVCHCPPGAHGPFC 103
Score = 67.7 bits (158), Expect = 2e-10
Identities = 34/97 (35%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 432 GRDCETNVDDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
G CE +VD+C CLHG TC D V + C C + GR CS+ + C C C
Sbjct: 20 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 79
Query: 491 VDL----LNAYRCICPVGFSGTNCEDDRDH--CAGSP 521
+ + +++Y C CP G G C + AGSP
Sbjct: 80 IPIFESGVHSYVCHCPPGAHGPFCGQNTTFSVMAGSP 116
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/142 (33%), Positives = 56/142 (39%), Gaps = 20/142 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHP---THGRC----DRPGDCDCRPGWRGELC------SQCQ 244
C PGW+G CE V + CH GRC D +C C PG+ G C +C
Sbjct: 750 CGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 807
Query: 245 PYPGCKHGY-CNGSS--WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFC 301
C G C G S +C+C G C C + PC +GGTC A C
Sbjct: 808 LNVTCLDGSPCEGRSPAANCSCLEGLAGQRCQVPTLPCEAN-PCLNGGTC-RAAGGVSEC 865
Query: 302 RCAEGFSGVDCERVDNPCAPQP 323
C FSG CE P P
Sbjct: 866 ICNARFSGQFCEVAKGLPLPLP 887
Score = 56.4 bits (130), Expect = 5e-07
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYY 536
D C+P PC NGG C+ N + C CP F+G C C G PC A C +
Sbjct: 477 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 535
Query: 537 C 537
C
Sbjct: 536 C 536
Score = 55.2 bits (127), Expect = 1e-06
Identities = 43/168 (25%), Positives = 55/168 (32%), Gaps = 17/168 (10%)
Query: 517 CAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCAN 576
CA SPC + AC + C C PGW G C V+ C CA
Sbjct: 728 CAPSPCLHDGACRDLFDAFACACGPGWEGPR-----------CEAHVDP---CHSAPCAR 773
Query: 577 GGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCR 636
G +G + G C P C C
Sbjct: 774 GRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD-GSPC--EGRSPAANCSCL 830
Query: 637 EGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAV 684
EG G C++ C ++PC NGG C G C C A ++G+ C V
Sbjct: 831 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 878
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 269 GILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPC-AHG 327
G C++D++ C +PC HGGTC +T Y CRC E + G DC C C
Sbjct: 20 GPTCEEDVDEC-LSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLTGCQGHTCPLAA 77
Query: 328 TC--SLAGTTRGFTCTCDRGWGG 348
TC + C C G G
Sbjct: 78 TCIPIFESGVHSYVCHCPPGAHG 100
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 308 SGVDCERVDNPCAPQPCAHG-TCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHG 366
+G CE + C PC HG TCS T G+ C C WGG C
Sbjct: 19 AGPTCEEDVDECLSDPCLHGGTCS--DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLA 76
Query: 367 ASC----RDHLDGFTCECADGWTGPACAED 392
A+C + + C C G GP C ++
Sbjct: 77 ATCIPIFESGVHSYVCHCPPGAHGPFCGQN 106
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 384 WTGP--ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD-CETNVD 440
W GP C +D+ G + L P N++ + G S AG D C +
Sbjct: 427 WGGPFRGCLQDL-RLDGCHLPFFPL-PLDNSSQPSELGGRQSWNLTAGCVSEDMCSPD-- 482
Query: 441 DCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
C +G TC+ +DFHC C A + G TC+ + C +PC C ++ + + C+
Sbjct: 483 ----PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 537
Query: 501 C--------PVGFSGTNCEDDR 514
P FSG N R
Sbjct: 538 AEATFREGPPAAFSGHNASSGR 559
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 360 SGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
S PCLHG +C D + G+ C C + W G C+ + C G + A C+ +
Sbjct: 32 SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAA--TCI--PIFESGV 87
Query: 420 GGYSCACLAGWTGRDCETN 438
Y C C G G C N
Sbjct: 88 HSYVCHCPPGAHGPFCGQN 106
Score = 44.8 bits (101), Expect = 0.002
Identities = 17/47 (36%), Positives = 25/47 (53%)
Query: 641 GALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVS 687
G CE +D C S PC +GG C ++C C W G C+V+++
Sbjct: 20 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLT 66
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 477 DDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+ C P PC +GG CVDL +RC C G C D+
Sbjct: 275 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 311
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/56 (35%), Positives = 26/56 (46%)
Query: 631 WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
+AC C G G CE +D C S+PC G G + C C G+ G C + V
Sbjct: 746 FACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPV 801
Score = 42.3 bits (95), Expect = 0.008
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 515 DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
D C+ PC NG C +D++C C +TG C Q+
Sbjct: 477 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 513
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G +C + F C C +TGP CA+ + C G+ PC+ A C G
Sbjct: 483 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--------PCLPPATCEEVPDG 533
Query: 422 YSCACLA 428
+ C A
Sbjct: 534 FVCVAEA 540
Score = 41.9 bits (94), Expect = 0.011
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDV 393
PC+HG SC D F C+CA GP CA+++
Sbjct: 281 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 312
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/38 (44%), Positives = 22/38 (57%)
Query: 646 LSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCA 683
+S D+C PC NGG C+ + C C A +TG TCA
Sbjct: 474 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 511
Score = 38.7 bits (86), Expect = 0.10
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
C+HG +C+DL F C CA + G TC+ ++
Sbjct: 282 CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 312
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 243 CQPYPGCKHGYC--NGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYF 300
C P P G C + + CTC N+ G C Q L +C +PC TCE PD +
Sbjct: 479 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WC-PGQPCLPPATCEE-VPDGFV 535
Query: 301 C 301
C
Sbjct: 536 C 536
Score = 36.7 bits (81), Expect = 0.41
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 619 GGTCLPSALP-PGWACGCRE------GRTGALCEL-SLDLCGSSPCRNGGRCVGGSGWWM 670
GG LP A P PG A G RE G + +C SPC + G C +
Sbjct: 688 GGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA 747
Query: 671 CECVAGWTGETCAVRV 686
C C GW G C V
Sbjct: 748 CACGPGWEGPRCEAHV 763
Score = 35.9 bits (79), Expect = 0.72
Identities = 22/76 (28%), Positives = 27/76 (35%), Gaps = 6/76 (7%)
Query: 242 QCQPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTC---ENTAP 296
+C P G C+ + + C C WGG C L C H C TC +
Sbjct: 29 ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH-TCPLAATCIPIFESGV 87
Query: 297 DQYFCRCAEGFSGVDC 312
Y C C G G C
Sbjct: 88 HSYVCHCPPGAHGPFC 103
Score = 33.5 bits (73), Expect = 3.8
Identities = 21/68 (30%), Positives = 26/68 (38%), Gaps = 6/68 (8%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCV----GGSGWWMCECV 674
GGTC S G+ C C E G C + L C C C+ G ++C C
Sbjct: 38 GGTC--SDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCP 95
Query: 675 AGWTGETC 682
G G C
Sbjct: 96 PGAHGPFC 103
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 108 bits (259), Expect = 1e-22
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 51/331 (15%)
Query: 249 CKHGYCNGSSWDCTCDTNWGGILCDQ-----DLNYCGTHEPCQHG-GTCENTAPDQYFCR 302
C HG C D +C N G Q D+N C EPC G G C NT Y C
Sbjct: 664 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA-EPCGPGRGICMNTG-GSYNCH 721
Query: 303 CAEGF------SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW---GGXXXXX 353
C G+ G C ++ P C G + + C C G+
Sbjct: 722 CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGYRLKASRPPVC 780
Query: 354 XXXXXASGP--CLHGASCRDHLDGFTC-ECADGWT---GPACAEDVDECSGRSMTEGALG 407
P C G C + F C C G+ G AC DV+EC+ EG+
Sbjct: 781 EDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGAC-RDVNECA-----EGS-- 831
Query: 408 PCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDC-TGQCLHGATCIDLVDDFHCA 462
PC + C N G + C C G+ GR C +VD+C G C + F C
Sbjct: 832 PC-SPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQCQ 889
Query: 463 CAAGY---AGRTCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVG---FSGTNCEDDRD 515
C +GY R+ D+D+C P C GG+C++ +YRC+CP G G C+ D D
Sbjct: 890 CLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DID 947
Query: 516 HCAGSP--CGNGAACYTAQSDYYCHCAPGWT 544
C+ P C AC Q Y C C G+T
Sbjct: 948 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 978
Score = 97.9 bits (233), Expect = 2e-19
Identities = 115/445 (25%), Positives = 168/445 (37%), Gaps = 62/445 (13%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKE--GCH-PTH---GRCD-RPGD--C-DCRPGW 235
GHY C +C PG++ PVC++ C P+ G+C+ +PG C C+PG+
Sbjct: 760 GHYKC------NCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 813
Query: 236 R---GELC---SQCQPYPGCKHGYCNG--SSWDCTCDTNWG----GILCDQDLNYCGTHE 283
R G C ++C C G+C S+ CTC + G C D++ C +
Sbjct: 814 RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGD 872
Query: 284 PCQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFT 339
C + G C NT P + C+C G+ CE +D P C G C T +
Sbjct: 873 VCDN-GICSNT-PGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC--INTNGSYR 928
Query: 340 CTCDRGWG--GXXXXXXXXXXASGP--CLHGASCRDHLDGFTCECADGWT---GPACAED 392
C C +G G + P CL +C++ + C C +G+T E+
Sbjct: 929 CLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEE 988
Query: 393 VDECSGRS---MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHG 449
V++ + + C + A N T C+ AGW G CE
Sbjct: 989 VEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEIYPCPVYSSAEFH 1047
Query: 450 ATCIDLVDDFHCACAAGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGF-- 505
+ C D Y G D+D+C G+CV+ Y C C GF
Sbjct: 1048 SLCPDGKGYTQDNNIVNY-GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYY 1106
Query: 506 SGTNCE-DDRDHCAG-SPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLV 563
G E D D C S C NG C + Y C C P + + R+ S
Sbjct: 1107 DGNLLECVDVDECLDESNCRNG-VCENTRGGYRCACTPP------AEYSPAQRQCLSPEE 1159
Query: 564 EESERCAEGMCANGGTCVREEGSWR 588
+ + C + G CV GS+R
Sbjct: 1160 MDVDECQDPAACRPGRCVNLPGSYR 1184
Score = 86.6 bits (205), Expect = 4e-16
Identities = 90/343 (26%), Positives = 130/343 (37%), Gaps = 55/343 (16%)
Query: 363 CLHGASCRDHLDGFTCECADGWTGPA----CAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C HG C ++C C G+ C DV+EC GP C NT
Sbjct: 664 CGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCV-DVNECEAEPC-----GP--GRGICMNT 714
Query: 419 AGGYSCACLAGWT------GRDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGY--- 467
G Y+C C G+ GR C ++++C C G CI+ + C C GY
Sbjct: 715 GGSYNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLK 773
Query: 468 AGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCI-CPVGF---SGTNCEDDRDHCAGS 520
A R C D+D+C P C +G +C + +++CI C G+ G C D + GS
Sbjct: 774 ASRPPVCE-DIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 831
Query: 521 PCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTC 580
PC G C + C CA G+ A D ++C + + C G + G C
Sbjct: 832 PCSPGW-CENLPGSFRCTCAQGYA-------PAPDGRSCL----DVDECEAGDVCDNGIC 879
Query: 581 VREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT 640
GS++ D GG C+ + + C C +G
Sbjct: 880 SNTPGSFQCQCLSGYHLSR-DRSHCEDIDECDFPAACIGGDCINTN--GSYRCLCPQGHR 936
Query: 641 ---GALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
G C+ +D C P C G C G ++C C G+T
Sbjct: 937 LVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 978
Score = 77.8 bits (183), Expect = 2e-13
Identities = 112/438 (25%), Positives = 161/438 (36%), Gaps = 78/438 (17%)
Query: 198 CLPGW--QGDNCEKPV--CKEGCHPTHGRCDR-PGD--CDCRPGWR----GELC---SQC 243
C PG+ QG + V C EG + G C+ PG C C G+ G C +C
Sbjct: 809 CQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC 868
Query: 244 QPYPGCKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQH-----GGTCENTAP 296
+ C +G C+ + S+ C C G +D ++C + C GG C NT
Sbjct: 869 EAGDVCDNGICSNTPGSFQCQC---LSGYHLSRDRSHCEDIDECDFPAACIGGDCINTN- 924
Query: 297 DQYFCRCAEGF---SGVDCERVDNPCAPQP--CA-HGTC-SLAGTTRGFTCTCDRGWGGX 349
Y C C +G G C+ +D C+ P C HG C +L G+ + C CD G+
Sbjct: 925 GSYRCLCPQGHRLVGGRKCQDIDE-CSQDPSLCLPHGACKNLQGS---YVCVCDEGFTPT 980
Query: 350 XXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS-GRSMTEGA-LG 407
H C + D T C D + CS G + +
Sbjct: 981 QDQHGCEEVEQPH--HKKECYLNFDD-TVFC-DSVLATNVTQQECCCSLGAGWGDHCEIY 1036
Query: 408 PC-VNAAA-----CNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVDD 458
PC V ++A C + G + + G ++D+C + C++
Sbjct: 1037 PCPVYSSAEFHSLCPDGKGYTQDNNIVNY-GIPAHRDIDECMLFGSEICKEGKCVNTQPG 1095
Query: 459 FHCACAAG--YAGRTCS-LDVDDCAPRPCTNGGECVDLLNAYRCIC--PVGFSGTN--C- 510
+ C C G Y G +DVD+C G C + YRC C P +S C
Sbjct: 1096 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCL 1155
Query: 511 ---EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGW----TGKNC------TQRAARDRK 557
E D D C C Y C C P W +G++C +RA R
Sbjct: 1156 SPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRD 1215
Query: 558 TCSVLVEESERCAEGMCA 575
C S+R +GMCA
Sbjct: 1216 VC-----WSQRGEDGMCA 1228
Score = 77.0 bits (181), Expect = 3e-13
Identities = 106/370 (28%), Positives = 140/370 (37%), Gaps = 67/370 (18%)
Query: 188 YSCTPDGDKHCLPGWQGDNCEK-PVCKEG-CHPTHGRCDRPGDCDCRPGWR-------GE 238
Y+ PDG + CL D CE VC G C T G C C G+ E
Sbjct: 853 YAPAPDG-RSCL---DVDECEAGDVCDNGICSNTPGSFQ----CQCLSGYHLSRDRSHCE 904
Query: 239 LCSQCQPYPGCKHGYC--NGSSWDCTCDTNW---GGILCDQDLNYCGTHEP--CQHGGTC 291
+C C G C S+ C C GG C QD++ C + +P C G C
Sbjct: 905 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKC-QDIDEC-SQDPSLCLPHGAC 962
Query: 292 ENTAPDQYFCRCAEGFSGVD----CERVDNPCAPQPC---------AHGTCSLAGTTRGF 338
+N Y C C EGF+ CE V+ P + C + T +
Sbjct: 963 KNLQ-GSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQEC 1021
Query: 339 TCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSG 398
C+ GWG +S H C D G+T + G D+DEC
Sbjct: 1022 CCSLGAGWGDHCEIYPCPVYSSAE-FHSL-CPDG-KGYTQDNNIVNYGIPAHRDIDEC-- 1076
Query: 399 RSMTEGALGPCVNAAACNNTAGGYSCACLAG--WTGRDCE-TNVDDCTGQ--CLHGATCI 453
M G+ C NT GY C C G + G E +VD+C + C +G C
Sbjct: 1077 --MLFGS--EICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGV-CE 1131
Query: 454 DLVDDFHCACA--AGY--AGRTC----SLDVDDCAPRPCTNGGECVDLLNAYRCIC---- 501
+ + CAC A Y A R C +DVD+C G CV+L +YRC C
Sbjct: 1132 NTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPW 1191
Query: 502 PVGFSGTNCE 511
G SG +C+
Sbjct: 1192 VPGPSGRDCQ 1201
Score = 74.5 bits (175), Expect = 2e-12
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 34/259 (13%)
Query: 437 TNVDDCT---GQCLHGATCIDLVDDFHCACAAGYAG----RTCSLDVDDCAPRPCTNG-G 488
T D+C C HG C+ D+ C C GY R C +DV++C PC G G
Sbjct: 652 TETDECRLNQNICGHGE-CVPGPPDYSCHCNPGYRSHPQHRYC-VDVNECEAEPCGPGRG 709
Query: 489 ECVDLLNAYRCICP------VGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG 542
C++ +Y C C VG G +C D + CG+G C Y C+C PG
Sbjct: 710 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 769
Query: 543 WTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDS 602
+ K D C + C +G C N + GS++
Sbjct: 770 YRLKASRPPVCEDIDEC----RDPSSCPDGKCEN------KPGSFKCIACQPGYRSQGGG 819
Query: 603 XXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRT----GALCELSLDLCGSSPCRN 658
+ G C LP + C C +G G C L +D C + +
Sbjct: 820 ACRDVNECAEGSPC-SPGWC--ENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCD 875
Query: 659 GGRCVGGSGWWMCECVAGW 677
G C G + C+C++G+
Sbjct: 876 NGICSNTPGSFQCQCLSGY 894
Score = 48.4 bits (110), Expect = 1e-04
Identities = 74/293 (25%), Positives = 105/293 (35%), Gaps = 43/293 (14%)
Query: 249 CKHGYCNGSS--WDCTCDTNW---GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRC 303
CK G C + ++C C + G +L D++ C C++G CENT Y C C
Sbjct: 1084 CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG-VCENTRGG-YRCAC 1141
Query: 304 AEGFSGVDCER---------VDNPCAPQPCAHGTC-SLAGTTRGFTCTCDRGWGGXXXXX 353
+R VD P C G C +L G+ R C C W
Sbjct: 1142 TPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYR---CECRPPWVPGPSGR 1198
Query: 354 XXXXXASGPCLHGASCRD---HLDGFTCECADGWTGPACAEDVDECSGRSMTEGA-LGPC 409
S P RD G CA GPA D D C + GA PC
Sbjct: 1199 DCQLPES-PAERAPERRDVCWSQRGEDGMCAGPLAGPALTFD-DCCCRQGRGWGAQCRPC 1256
Query: 410 VNAAACNNTAGGYS--------CACLAGWTGRDCETNVDDCTG-QCLHGATCIDLVDDFH 460
A ++ S L G RD +++ +D +C+ G C+
Sbjct: 1257 PPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGR-CVPRPGGAV 1315
Query: 461 CACAAGY---AGRTCSLDVDDCAPRP----CTNGGECVDLLNAYRCICPVGFS 506
C C G+ A R +D+D+C CV+ ++RC+C GF+
Sbjct: 1316 CECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFA 1368
Score = 38.3 bits (85), Expect = 0.13
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 15/125 (12%)
Query: 463 CAAGYA--GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS 520
C GY T D+++CA G+C++ +YRC+CP G S R C
Sbjct: 420 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHS---LGPSRTQCIAD 476
Query: 521 PCGNGAACYTAQS-DYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGT 579
+ C+ S ++ C T R R CSV RC C GT
Sbjct: 477 KPEEKSLCFRLVSPEHQCQ-------HPLTTRLTRQLCCCSVGKAWGARCQR--CPTDGT 527
Query: 580 CVREE 584
+E
Sbjct: 528 AAFKE 532
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNG 525
P PC NGG+C + +C+CP F+G C+ G G+G
Sbjct: 193 PLPCMNGGQCS---SRNQCLCPPDFTGRFCQVPAGGAGGGTGGSG 234
>AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein.
Length = 2144
Score = 107 bits (257), Expect = 2e-22
Identities = 77/255 (30%), Positives = 105/255 (41%), Gaps = 36/255 (14%)
Query: 186 GHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCS---- 241
GH SC DG+ C G++G++CE+ C + +HG C G+C C PGW G C
Sbjct: 17 GHGSCI-DGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVN-GECLCSPGWGGLNCELARV 74
Query: 242 QCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNY--CGTHEPCQHGGTCENTAPDQY 299
QC P HG + C+CD NW G C ++ CGTH C G
Sbjct: 75 QC-PDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGA---------- 123
Query: 300 FCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXA 359
CRC EG++G C++ C P+ HGTC + C C GW G
Sbjct: 124 -CRCEEGWTGAACDQ--RVCHPRCIEHGTC------KDGKCECREGWNGEHCTIGRQTAG 174
Query: 360 SGP------CLHGASCRDHLDGFTCECADGWTGPACAEDVD-ECSGRSMTEG-ALGPCVN 411
+ C C + + C C GW GP C ++ C+ EG L C++
Sbjct: 175 TETDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLD 234
Query: 412 AAACNNTAGGYSCAC 426
C +A S C
Sbjct: 235 PDCCLQSACQNSLLC 249
Score = 97.5 bits (232), Expect = 2e-19
Identities = 73/246 (29%), Positives = 94/246 (38%), Gaps = 45/246 (18%)
Query: 272 CDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSL 331
CD +N C C G+C + C C+ G+ G CE VD C TCS
Sbjct: 3 CDVPMNQC-IDPSCGGHGSCIDGN-----CVCSAGYKGEHCEEVD-------CLDPTCSS 49
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE 391
G C C GWGG HG D G C C W GP C+
Sbjct: 50 HGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPD--TGL-CSCDPNWMGPDCSV 106
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGAT 451
+V CS + G G C+ A C C GWTG C+ V C +C+ T
Sbjct: 107 EV--CS---VDCGTHGVCIGGA----------CRCEEGWTGAACDQRV--CHPRCIEHGT 149
Query: 452 CIDLVDDFHCACAAGYAGRTCSL-------DVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
C D C C G+ G C++ + D C P C G C N+++C+C G
Sbjct: 150 C----KDGKCECREGWNGEHCTIGRQTAGTETDGC-PDLCNGNGRCTLGQNSWQCVCQTG 204
Query: 505 FSGTNC 510
+ G C
Sbjct: 205 WRGPGC 210
Score = 71.7 bits (168), Expect = 1e-11
Identities = 52/222 (23%), Positives = 71/222 (31%), Gaps = 21/222 (9%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA 531
C + ++ C C G C+D C+C G+ G +CE+ C C + C
Sbjct: 3 CDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCEEV--DCLDPTCSSHGVCVNG 56
Query: 532 QSDYYCHCAPGWTGKNCTQRAARDRKTCS---VLVEESERCAEGMCANGGTCVREEGSWR 588
+ C C+PGW G NC + CS + ++ C+ G C E S
Sbjct: 57 E----CLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVD 112
Query: 589 XXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALCELSL 648
C+ C CREG G C +
Sbjct: 113 CGTHGVCIGGACRCEEGWTGAACDQRVCHP--RCIEHGTCKDGKCECREGWNGEHCTIGR 170
Query: 649 DLCGSSP------CRNGGRCVGGSGWWMCECVAGWTGETCAV 684
G+ C GRC G W C C GW G C V
Sbjct: 171 QTAGTETDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNV 212
Score = 70.9 bits (166), Expect = 2e-11
Identities = 73/284 (25%), Positives = 99/284 (34%), Gaps = 50/284 (17%)
Query: 311 DCERVDNPCAPQPCA-HGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASC 369
+C+ N C C HG+C + G C C G+ G + C C
Sbjct: 2 ECDVPMNQCIDPSCGGHGSC-IDGN-----CVCSAGYKGEHCEEVDCLDPT--CSSHGVC 53
Query: 370 RDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAG 429
++G C C+ GW G C +C + G P C+C
Sbjct: 54 ---VNG-ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGL-----------CSCDPN 98
Query: 430 WTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGE 489
W G DC V C+ C CI C C G+ G C V C PR C G
Sbjct: 99 WMGPDCSVEV--CSVDCGTHGVCIGGA----CRCEEGWTGAACDQRV--CHPR-CIEHGT 149
Query: 490 CVDLLNAYRCICPVGFSGTNCEDDRDHCA----GSP--CGNGAACYTAQSDYYCHCAPGW 543
C D +C C G++G +C R G P C C Q+ + C C GW
Sbjct: 150 CKD----GKCECREGWNGEHCTIGRQTAGTETDGCPDLCNGNGRCTLGQNSWQCVCQTGW 205
Query: 544 TGKNCT---QRAARDRK--TCSVLVE--ESERCAEGMCANGGTC 580
G C + + D K LV+ + + C + C N C
Sbjct: 206 RGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 249
Score = 45.6 bits (103), Expect = 9e-04
Identities = 48/177 (27%), Positives = 64/177 (36%), Gaps = 40/177 (22%)
Query: 510 CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERC 569
C+ + C CG +C D C C+ G+ G++C + D TCS
Sbjct: 3 CDVPMNQCIDPSCGGHGSCI----DGNCVCSAGYKGEHCEEVDCLD-PTCS--------- 48
Query: 570 AEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPP 629
+ G+C NG C+ G W D GT LP
Sbjct: 49 SHGVCVNG-ECLCSPG-WGGLNCELARVQCPDQCSGH-------------GTYLPDT--- 90
Query: 630 GWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
C C G C S+++C S C G C+GG+ C C GWTG C RV
Sbjct: 91 -GLCSCDPNWMGPDC--SVEVC-SVDCGTHGVCIGGA----CRCEEGWTGAACDQRV 139
Score = 32.3 bits (70), Expect = 8.8
Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 4/41 (9%)
Query: 642 ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
A C++ ++ C C G C+ G+ C C AG+ GE C
Sbjct: 1 AECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHC 37
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 106 bits (255), Expect = 3e-22
Identities = 95/347 (27%), Positives = 144/347 (41%), Gaps = 62/347 (17%)
Query: 241 SQCQPYPG-CKHGYCNGS--SWDCTCDTNWGGILCDQDLNYCGTHEPCQHG------GTC 291
++C+ P C HG C + S+ C CD+ G D + C + C+ G C
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDS---GFALDSEERNCTDIDECRISPDLCGRGQC 1086
Query: 292 ENTAPDQYFCRCAEGF-SGV----DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDR 344
NT P + C+C EG+ SG +C +D C P C G C T + C C
Sbjct: 1087 VNT-PGDFECKCDEGYESGFMMMKNCMDIDE-CQRDPLLCRGGVCH--NTEGSYRCECPP 1142
Query: 345 GWG-----GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA----CAEDVDE 395
G ++ C +G C + + + C C G+ C D+DE
Sbjct: 1143 GHQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQCACNPGYHSTPDRLFCV-DIDE 1200
Query: 396 CSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQ--CLHG 449
CS + G C C N+ G Y C+C G+ R C T++D+C G
Sbjct: 1201 CSIMN------GGC--ETFCTNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDG 1251
Query: 450 ATCIDLVDDFHCACAAGYAG----RTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPV 503
C ++ ++ C C G+ +TC +DV++C P C +G C + ++ C C +
Sbjct: 1252 GQCTNIPGEYRCLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDM 1309
Query: 504 GFSG----TNCEDDRDHCAGSP-CGNGAACYTAQSDYYCHCAPGWTG 545
G+SG T C D + G+ CG A C + C C+PGW G
Sbjct: 1310 GYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356
Score = 102 bits (245), Expect = 6e-21
Identities = 108/421 (25%), Positives = 160/421 (38%), Gaps = 61/421 (14%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQC--QPYPGCKHGYCN 255
C ++ + C P+ G H C C W E C +C + P +
Sbjct: 958 CFLRYEDEECTLPIA--GRHRMDACC-----CSVGAAWGTEECEECPMRNTPEYEELCPR 1010
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GV 310
G + TN G +D+N C C HG C NT + CRC GF+
Sbjct: 1011 GPGFATKEITN--GKPFFKDINECKMIPSLCTHG-KCRNTI-GSFKCRCDSGFALDSEER 1066
Query: 311 DCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----GPCL- 364
+C +D +P C G C T F C CD G+ P L
Sbjct: 1067 NCTDIDECRISPDLCGRGQC--VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 1124
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C + + CEC G + ++ C + E + C N C N G Y C
Sbjct: 1125 RGGVCHNTEGSYRCECPPGHQ---LSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC 1180
Query: 425 ACLAGWTGRDCE---TNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSL 474
AC G+ ++D+C+ G C C + + C+C G+A R+C+
Sbjct: 1181 ACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCT- 1237
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN----CEDDRDHCAGSP--CGNGAA 527
D+D+C P +GG+C ++ YRC+C GF + C D + C +P C +G
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE-CDLNPNICLSGT- 1295
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
C + + CHC G++GK KT + E E A C C GS+
Sbjct: 1296 CENTKGSFICHCDMGYSGKK--------GKTGCTDINECEIGAHN-CGKHAVCTNTAGSF 1346
Query: 588 R 588
+
Sbjct: 1347 K 1347
Score = 97.1 bits (231), Expect = 3e-19
Identities = 135/525 (25%), Positives = 188/525 (35%), Gaps = 84/525 (16%)
Query: 205 DNCE--KPVCKEG-CHPTHGRCDRPGDCDCRPGW----RGEL--CSQCQPYPGCKHGYC- 254
D C+ + +C+ G C PT G C C+C G+ RGE +C+ P C G C
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCR----CECNKGFQLDLRGECIDVDECEKNP-CAGGECI 505
Query: 255 -NGSSWDCTCDTNWGGILCD---QDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGF--- 307
N S+ C C + L +D++ C + + G C NT + C C GF
Sbjct: 506 NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT-DGSFHCVCNAGFHVT 564
Query: 308 -SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGP 362
G +CE +D C +G C F C C G+ G G
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMC--INEDGSFKCICKPGFQLASDGRYCKDINECETPGI 622
Query: 363 CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGAL--GPCVNAAACNNTAG 420
C++G C + + CEC G + RS G G C+ T
Sbjct: 623 CMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKS 681
Query: 421 GYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
CA G C+ C Q + A ++ C++G + D+++CA
Sbjct: 682 ECCCASTEYAFGEPCQ----PCPAQ--NSA-------EYQALCSSGPGMTSAGSDINECA 728
Query: 481 --PRPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCAGS-PCGNGAACYTAQS 533
P C N G C +L Y+CIC G+ +G NC D + S C NG C
Sbjct: 729 LDPDICPN-GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG-QCRNTPG 786
Query: 534 DYYCHCAPGWTGKNCTQRAARDRKTCSVLVE-ESERCAEGMCANG-GTCVREEGSWRXXX 591
+ C C G+ K D KTC + E ES C G+C N G+ + E S
Sbjct: 787 SFVCTCPKGFIYK-------PDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
Query: 592 XXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLP----SALPPGWA-----------CGCR 636
G L S+L W CG
Sbjct: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
Query: 637 EGR-TGALCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWT 678
R G CE +D C P C+N G CV G + C+C +G T
Sbjct: 900 YSRIKGTQCE-DIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMT 942
Score = 87.8 bits (208), Expect = 2e-16
Identities = 98/344 (28%), Positives = 128/344 (37%), Gaps = 68/344 (19%)
Query: 190 CTPDGDKHCLPGWQ----GDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQP 245
C + +C PGW+ G+ C P+C+ C G C RP C C G C +
Sbjct: 59 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGD--GFCSRPNMCTCPSGQIAPSCGS-RS 115
Query: 246 YPGCKHGYCNGSSWD---CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCR 302
C NG S C C + G C Q + G C +GG C AP++ C
Sbjct: 116 IQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG----CLNGGRC--VAPNR--CA 167
Query: 303 CAEGFSGVDCER--VDNPC----APQPCAHGTCSLAGTTRGFTC-TCDRGWGGXXXXXXX 355
C GF+G CER PC + Q C G S T+ C T R WG
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSGIVCTKTLCCATVGRAWG-------- 218
Query: 356 XXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
PC + A GF G AC +DVDEC + G C
Sbjct: 219 -----HPCEMCPAQPHPCRRGFIPNIRTG----AC-QDVDEC------QAIPGLC-QGGN 261
Query: 415 CNNTAGGYSCACLAGW----TGRDCETNVDDCT---GQCLHGATCIDLVDDFHCACAAGY 467
C NT G + C C AG + CE ++D+C+ G C G C + V + C C G+
Sbjct: 262 CINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGIC-EGGECTNTVSSYFCKCPPGF 319
Query: 468 AGRTCSLDVDDCAPRPC----TNG---GECVDLLNAYRCICPVG 504
D P C TNG + + +C C G
Sbjct: 320 YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 82.2 bits (194), Expect = 8e-15
Identities = 99/365 (27%), Positives = 135/365 (36%), Gaps = 74/365 (20%)
Query: 231 CRPGWR----GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNYCGTHEPC 285
C PGW+ G C C G+C+ + CTC + C + + +C C
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNM-CTCPSGQIAPSCGSRSIQHCNIR--C 123
Query: 286 QHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
+GG+C + C C +G+ G C + P C +G +A C C G
Sbjct: 124 MNGGSCSDD-----HCLCQKGYIGTHCGQ---PVCESGCLNGGRCVAPNR----CACTYG 171
Query: 346 WGGXXXXXXXXXXASGPC---LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR--S 400
+ G +GPC + C+ L G C T C V G
Sbjct: 172 FTGPQCERDYR---TGPCFTVISNQMCQGQLSGIVC------TKTLCCATVGRAWGHPCE 222
Query: 401 MTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCT---GQCLHGATCIDLVD 457
M PC N G AC +VD+C G C G CI+ V
Sbjct: 223 MCPAQPHPCRRGFIPNIRTG----AC----------QDVDECQAIPGLC-QGGNCINTVG 267
Query: 458 DFHCACAAGY----AGRTCSLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGF----SGT 508
F C C AG+ + C D+D+C+ P GGEC + +++Y C CP GF GT
Sbjct: 268 SFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGT 326
Query: 509 NCEDDR-DHC----AGSPCGNGAACYTAQSDYYC---HC-APGWT--GKNCTQRAARD-R 556
C D R +C C N + C C +PG T + C RA D
Sbjct: 327 RCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFN 386
Query: 557 KTCSV 561
K CSV
Sbjct: 387 KLCSV 391
Score = 77.4 bits (182), Expect = 2e-13
Identities = 111/474 (23%), Positives = 165/474 (34%), Gaps = 73/474 (15%)
Query: 237 GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
G C+ CQ P C GY C +D++ C G C NT
Sbjct: 884 GSPCTLCQVDPICGKGYSRIKGTQC------------EDIDECEVFPGVCKNGLCVNTR- 930
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPC------AHGTCSLAGTTRGFTCTCDRGWGGXX 350
+ C+C G + R+ + C T +AG R C C G
Sbjct: 931 GSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGT 990
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
+ P R GF + + G +D++EC +
Sbjct: 991 EECEECPMRNTPEYEELCPRG--PGFATK--EITNGKPFFKDINECK-------MIPSLC 1039
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT---GQCLHGATCIDLVDDFHCAC 463
C NT G + C C +G+ R+C T++D+C C G C++ DF C C
Sbjct: 1040 THGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRGQ-CVNTPGDFECKC 1097
Query: 464 AAGYAG-----RTCSLDVDDCAPRPCT-NGGECVDLLNAYRCICPVGFS---GTNCEDDR 514
GY + C +D+D+C P GG C + +YRC CP G + D
Sbjct: 1098 DEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1156
Query: 515 DHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
+ C S C NG C Y C C PG+ + DR C V ++E G
Sbjct: 1157 NECELSAHLCPNGR-CVNLIGKYQCACNPGY-------HSTPDRLFC-VDIDECS-IMNG 1206
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA 632
C C EGS+ GG C + +P +
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1262
Query: 633 CGCREGRTGA----LCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTGE 680
C C +G + C + ++ C +P C +G C G ++C C G++G+
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSGK 1314
Score = 61.3 bits (142), Expect = 2e-08
Identities = 64/252 (25%), Positives = 94/252 (37%), Gaps = 34/252 (13%)
Query: 205 DNCEKP--VCKEG-CHPTHG--RCDRPGDCDCRPGWRGEL-CSQCQPYPG-CKHGYCNG- 256
D C++ +C+ G CH T G RC+ P P + ++C+ C +G C
Sbjct: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
Query: 257 -SSWDCTCDTNWGGILCDQDLNYCGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGV- 310
+ C C+ G D +C + C G CE + Y C C GF+ +
Sbjct: 1175 IGKYQCACNP---GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 311 ---DCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GP 362
C +D C P C G C+ + C C G+ P
Sbjct: 1232 DQRSCTDIDE-CEDNPNICDGGQCT--NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNP 1288
Query: 363 --CLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
CL G +C + F C C G++G + C+ + E C A C NTAG
Sbjct: 1289 NICLSG-TCENTKGSFICHCDMGYSGK---KGKTGCTDINECEIGAHNCGKHAVCTNTAG 1344
Query: 421 GYSCACLAGWTG 432
+ C+C GW G
Sbjct: 1345 SFKCSCSPGWIG 1356
Score = 43.6 bits (98), Expect = 0.004
Identities = 50/187 (26%), Positives = 66/187 (35%), Gaps = 19/187 (10%)
Query: 499 CICPVGFSGTNCEDDR-DHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRK 557
C CP G +C HC C NG +C SD +C C G+ G +C Q
Sbjct: 100 CTCPSGQIAPSCGSRSIQHC-NIRCMNGGSC----SDDHCLCQKGYIGTHCGQPVCESGC 154
Query: 558 TCSVLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXD-SXXXXXXXXXXXXXX 616
RCA G C R+ + S
Sbjct: 155 LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG 214
Query: 617 QAGGTCLPSALPPGWACGCREG-----RTGALCELSLDLCGSSP--CRNGGRCVGGSGWW 669
+A G P + P CR G RTGA C+ +D C + P C+ GG C+ G +
Sbjct: 215 RAWGH--PCEMCPAQPHPCRRGFIPNIRTGA-CQ-DVDECQAIPGLCQ-GGNCINTVGSF 269
Query: 670 MCECVAG 676
C+C AG
Sbjct: 270 ECKCPAG 276
Score = 43.2 bits (97), Expect = 0.005
Identities = 53/201 (26%), Positives = 69/201 (34%), Gaps = 43/201 (21%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHG 221
C P Y++T FC D+ + C + C C C+ G P
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECSIMNGGC----ETFCTNSEGSYECS---CQPGFALMPDQR 1234
Query: 222 RCDRPGDCDCRPGWRGELC--SQCQPYPG-----CKHGYCNGSSWDCTCDTNWGGILCDQ 274
C +C+ P +C QC PG C G+ D N CD
Sbjct: 1235 SCTDIDECEDNP----NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDL 1286
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG----VDCERVDNPC--APQPCA-HG 327
+ N C GTCENT + C C G+SG C + N C C H
Sbjct: 1287 NPNIC-------LSGTCENT-KGSFICHCDMGYSGKKGKTGCTDI-NECEIGAHNCGKHA 1337
Query: 328 TCSLAGTTRGFTCTCDRGWGG 348
C+ T F C+C GW G
Sbjct: 1338 VCT--NTAGSFKCSCSPGWIG 1356
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C++G G C +C S C NGGRCV + C C G+TG C
Sbjct: 134 CLCQKGYIGTHC--GQPVCESG-CLNGGRCVAPN---RCACTYGFTGPQC 177
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 106 bits (254), Expect = 4e-22
Identities = 101/364 (27%), Positives = 147/364 (40%), Gaps = 61/364 (16%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGS----------SWDCTCDTNWGGILCDQDLNY 278
C C+PG++GE QC+ C++ Y NG ++ CTC + G + D +
Sbjct: 59 CLCKPGYKGE-GKQCEDIDECENDYYNGGCVHECINIPGNYRCTC---FDGFMLAHDGHN 114
Query: 279 CGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGVDCER--VDNPCAPQPCA---HGTC 329
C + CQ + G C+ A Y C+C GF D + + C HG
Sbjct: 115 CLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCA 174
Query: 330 SLAGTTR--GFTCTCDRGWG---GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
+ T G C C G+ +G C H SC D G TC C +
Sbjct: 175 HICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH--SCEDTDTGPTCGCHQKY 232
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVD 440
A D C G C C +TA G C+C G+T G+ C+ +++
Sbjct: 233 ---ALHSDGRTCIETCAVNN--GGCDRT--CKDTATGVRCSCPVGFTLQPDGKTCK-DIN 284
Query: 441 DC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA-PRPCTNGGECVD 492
+C G C H C + V F C C GY RTC D+D+C+ R C + C++
Sbjct: 285 ECLVNNGGCDH--FCRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDH--ICIN 339
Query: 493 LLNAYRCICPVGFS--GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG----WTGK 546
+++C+C G+ GT D D C+ S C + Y C C PG W GK
Sbjct: 340 SPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGK 399
Query: 547 NCTQ 550
+C +
Sbjct: 400 DCVE 403
Score = 84.6 bits (200), Expect = 2e-15
Identities = 93/351 (26%), Positives = 135/351 (38%), Gaps = 64/351 (18%)
Query: 198 CLPGWQG--------DNCEKPVCKEGCHPTHGRCDRPGD--CDCRPGWR----GELC--- 240
C PG++G D CE GC H + PG+ C C G+ G C
Sbjct: 61 CKPGYKGEGKQCEDIDECENDYYNGGC--VHECINIPGNYRCTCFDGFMLAHDGHNCLDV 118
Query: 241 SQCQPYPG-CKHGYCNG-SSWDCTCDTNW----GGILC----DQDLNYCGTHEPCQHGGT 290
+CQ G C+ N S++C C + + C ++ +N C H
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--I 176
Query: 291 CENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT--C--SLAGTTRGFTCTCDRGW 346
C T C C GF D + C C +G C S T G TC C + +
Sbjct: 177 CRETPKGGVACDCRPGF---DLAQNQKDCT-LTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 347 GGXXXXXXXXXXAS---GPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGR 399
+ G C +C+D G C C G+T G C +D++EC
Sbjct: 233 ALHSDGRTCIETCAVNNGGC--DRTCKDTATGVRCSCPVGFTLQPDGKTC-KDINECLVN 289
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQCLHGATCIDL 455
+ G C + C NT G + C C G+ R C+ ++D+C+ + CI+
Sbjct: 290 N------GGCDHF--CRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDHICINS 340
Query: 456 VDDFHCACAAGYA--GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
F C C GY G T DVD+C+ + CV+ +Y C+CP G
Sbjct: 341 PGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 83.0 bits (196), Expect = 5e-15
Identities = 97/337 (28%), Positives = 133/337 (39%), Gaps = 65/337 (19%)
Query: 275 DLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGV--DCERVD---NPCAPQPCAHG 327
D++ C GT + C C+NT P Y C C G+ G CE +D N C H
Sbjct: 33 DVDECSEGTDD-CHIDAICQNT-PKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHE 90
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
++ G R CTC G+ G +G C C + + + C+C
Sbjct: 91 CINIPGNYR---CTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYECQCHS 145
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVN-----AAACNNTA-GGYSCACLAGWTGRDCE 436
G+ +++ C RS EG C+N A C T GG +C C G+ D
Sbjct: 146 GFF---LSDNQHTCIHRS-NEGM--NCMNKDHGCAHICRETPKGGVACDCRPGF---DLA 196
Query: 437 TNVDDCTGQCLHGA-----TCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNG 487
N DCT C +G +C D C C YA GRTC ++ CA NG
Sbjct: 197 QNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC---IETCA---VNNG 250
Query: 488 G---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
G C D RC CPVGF+ G C+D + C + G C + C C
Sbjct: 251 GCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE-CLVNNGGCDHFCRNTVGSFECGCR 309
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEES-ERCAEGMCAN 576
G+ + D +TC + E S ER + +C N
Sbjct: 310 KGY-------KLLTDERTCQDIDECSFERTCDHICIN 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 63/211 (29%), Positives = 90/211 (42%), Gaps = 39/211 (18%)
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW--TGRDCETNVD 440
G +G + DVDECS EG C A C NT Y C C G+ G+ CE ++D
Sbjct: 24 GGSGLPGSVDVDECS-----EGT-DDCHIDAICQNTPKSYKCLCKPGYKGEGKQCE-DID 76
Query: 441 DC-----TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGG--- 488
+C G C+H CI++ ++ C C G+ G C LDVD+C NGG
Sbjct: 77 ECENDYYNGGCVH--ECINIPGNYRCTCFDGFMLAHDGHNC-LDVDECQD---NNGGCQQ 130
Query: 489 ECVDLLNAYRCICPVGF----SGTNC---EDDRDHCAGSPCGNGAAC-YTAQSDYYCHCA 540
CV+ + +Y C C GF + C ++ +C G C T + C C
Sbjct: 131 ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCR 190
Query: 541 PGW----TGKNCTQRAARDRKTCSVLVEESE 567
PG+ K+CT C E+++
Sbjct: 191 PGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 465 AGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHCAGSP 521
AG +G S+DVD+C+ C C + +Y+C+C G+ G + +D D C
Sbjct: 23 AGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDY 82
Query: 522 CGNGAA--CYTAQSDYYCHCAPGW----TGKNC 548
G C +Y C C G+ G NC
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 106 bits (254), Expect = 4e-22
Identities = 101/364 (27%), Positives = 147/364 (40%), Gaps = 61/364 (16%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGS----------SWDCTCDTNWGGILCDQDLNY 278
C C+PG++GE QC+ C++ Y NG ++ CTC + G + D +
Sbjct: 59 CLCKPGYKGE-GKQCEDIDECENDYYNGGCVHECINIPGNYRCTC---FDGFMLAHDGHN 114
Query: 279 CGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGVDCER--VDNPCAPQPCA---HGTC 329
C + CQ + G C+ A Y C+C GF D + + C HG
Sbjct: 115 CLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCA 174
Query: 330 SLAGTTR--GFTCTCDRGWG---GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
+ T G C C G+ +G C H SC D G TC C +
Sbjct: 175 HICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH--SCEDTDTGPTCGCHQKY 232
Query: 385 TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVD 440
A D C G C C +TA G C+C G+T G+ C+ +++
Sbjct: 233 ---ALHSDGRTCIETCAVNN--GGCDRT--CKDTATGVRCSCPVGFTLQPDGKTCK-DIN 284
Query: 441 DC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA-PRPCTNGGECVD 492
+C G C H C + V F C C GY RTC D+D+C+ R C + C++
Sbjct: 285 ECLVNNGGCDH--FCRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDH--ICIN 339
Query: 493 LLNAYRCICPVGFS--GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG----WTGK 546
+++C+C G+ GT D D C+ S C + Y C C PG W GK
Sbjct: 340 SPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGK 399
Query: 547 NCTQ 550
+C +
Sbjct: 400 DCVE 403
Score = 84.6 bits (200), Expect = 2e-15
Identities = 93/351 (26%), Positives = 135/351 (38%), Gaps = 64/351 (18%)
Query: 198 CLPGWQG--------DNCEKPVCKEGCHPTHGRCDRPGD--CDCRPGWR----GELC--- 240
C PG++G D CE GC H + PG+ C C G+ G C
Sbjct: 61 CKPGYKGEGKQCEDIDECENDYYNGGC--VHECINIPGNYRCTCFDGFMLAHDGHNCLDV 118
Query: 241 SQCQPYPG-CKHGYCNG-SSWDCTCDTNW----GGILC----DQDLNYCGTHEPCQHGGT 290
+CQ G C+ N S++C C + + C ++ +N C H
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--I 176
Query: 291 CENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT--C--SLAGTTRGFTCTCDRGW 346
C T C C GF D + C C +G C S T G TC C + +
Sbjct: 177 CRETPKGGVACDCRPGF---DLAQNQKDCT-LTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 347 GGXXXXXXXXXXAS---GPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGR 399
+ G C +C+D G C C G+T G C +D++EC
Sbjct: 233 ALHSDGRTCIETCAVNNGGC--DRTCKDTATGVRCSCPVGFTLQPDGKTC-KDINECLVN 289
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQCLHGATCIDL 455
+ G C + C NT G + C C G+ R C+ ++D+C+ + CI+
Sbjct: 290 N------GGCDHF--CRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDHICINS 340
Query: 456 VDDFHCACAAGYA--GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
F C C GY G T DVD+C+ + CV+ +Y C+CP G
Sbjct: 341 PGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 83.0 bits (196), Expect = 5e-15
Identities = 97/337 (28%), Positives = 133/337 (39%), Gaps = 65/337 (19%)
Query: 275 DLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGV--DCERVD---NPCAPQPCAHG 327
D++ C GT + C C+NT P Y C C G+ G CE +D N C H
Sbjct: 33 DVDECSEGTDD-CHIDAICQNT-PKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHE 90
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
++ G R CTC G+ G +G C C + + + C+C
Sbjct: 91 CINIPGNYR---CTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYECQCHS 145
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVN-----AAACNNTA-GGYSCACLAGWTGRDCE 436
G+ +++ C RS EG C+N A C T GG +C C G+ D
Sbjct: 146 GFF---LSDNQHTCIHRS-NEGM--NCMNKDHGCAHICRETPKGGVACDCRPGF---DLA 196
Query: 437 TNVDDCTGQCLHGA-----TCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNG 487
N DCT C +G +C D C C YA GRTC ++ CA NG
Sbjct: 197 QNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC---IETCA---VNNG 250
Query: 488 G---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
G C D RC CPVGF+ G C+D + C + G C + C C
Sbjct: 251 GCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE-CLVNNGGCDHFCRNTVGSFECGCR 309
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEES-ERCAEGMCAN 576
G+ + D +TC + E S ER + +C N
Sbjct: 310 KGY-------KLLTDERTCQDIDECSFERTCDHICIN 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 63/211 (29%), Positives = 90/211 (42%), Gaps = 39/211 (18%)
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW--TGRDCETNVD 440
G +G + DVDECS EG C A C NT Y C C G+ G+ CE ++D
Sbjct: 24 GGSGLPGSVDVDECS-----EGT-DDCHIDAICQNTPKSYKCLCKPGYKGEGKQCE-DID 76
Query: 441 DC-----TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGG--- 488
+C G C+H CI++ ++ C C G+ G C LDVD+C NGG
Sbjct: 77 ECENDYYNGGCVH--ECINIPGNYRCTCFDGFMLAHDGHNC-LDVDECQD---NNGGCQQ 130
Query: 489 ECVDLLNAYRCICPVGF----SGTNC---EDDRDHCAGSPCGNGAAC-YTAQSDYYCHCA 540
CV+ + +Y C C GF + C ++ +C G C T + C C
Sbjct: 131 ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCR 190
Query: 541 PGW----TGKNCTQRAARDRKTCSVLVEESE 567
PG+ K+CT C E+++
Sbjct: 191 PGFDLAQNQKDCTLTCNYGNGGCQHSCEDTD 221
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 465 AGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHCAGSP 521
AG +G S+DVD+C+ C C + +Y+C+C G+ G + +D D C
Sbjct: 23 AGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDY 82
Query: 522 CGNGAA--CYTAQSDYYCHCAPGW----TGKNC 548
G C +Y C C G+ G NC
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
>D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein.
Length = 830
Score = 105 bits (252), Expect = 8e-22
Identities = 123/443 (27%), Positives = 158/443 (35%), Gaps = 86/443 (19%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+C G+ G C + C + P GE + + C G+ G CED
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341
Query: 514 -RDHCAGSPCGN------GAACYTAQSDYYCHCAPGWTGKNCTQR--AARDRKTCSVLVE 564
G CG+ +C T D C C+ G+ G +C A CSV E
Sbjct: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCE 399
Query: 565 ESERCAEGMC-ANGGTCVREEGS 586
C EG+C G+C GS
Sbjct: 400 ----CPEGLCHPVSGSCQPGSGS 418
Score = 85.4 bits (202), Expect = 9e-16
Identities = 76/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNP------CAPQ--PCAHGTC 329
C H G C E +PD C C G++G C++ P C Q C HG
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--------PCLHGASCRDHLDGFTCECA 381
T G CD GW G G C+ G SC D + G C C+
Sbjct: 319 CEPDT--GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG-SC-DTVTG-DCVCS 373
Query: 382 DGWTGPAC 389
G+ GP+C
Sbjct: 374 AGYWGPSC 381
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
>D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein.
Length = 830
Score = 105 bits (252), Expect = 8e-22
Identities = 123/443 (27%), Positives = 158/443 (35%), Gaps = 86/443 (19%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+C G+ G C + C + P GE + + C G+ G CED
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341
Query: 514 -RDHCAGSPCGN------GAACYTAQSDYYCHCAPGWTGKNCTQR--AARDRKTCSVLVE 564
G CG+ +C T D C C+ G+ G +C A CSV E
Sbjct: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCE 399
Query: 565 ESERCAEGMC-ANGGTCVREEGS 586
C EG+C G+C GS
Sbjct: 400 ----CPEGLCHPVSGSCQPGSGS 418
Score = 85.4 bits (202), Expect = 9e-16
Identities = 76/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNP------CAPQ--PCAHGTC 329
C H G C E +PD C C G++G C++ P C Q C HG
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--------PCLHGASCRDHLDGFTCECA 381
T G CD GW G G C+ G SC D + G C C+
Sbjct: 319 CEPDT--GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG-SC-DTVTG-DCVCS 373
Query: 382 DGWTGPAC 389
G+ GP+C
Sbjct: 374 AGYWGPSC 381
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
>BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor class
F, member 1 protein.
Length = 830
Score = 105 bits (252), Expect = 8e-22
Identities = 123/443 (27%), Positives = 158/443 (35%), Gaps = 86/443 (19%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+C G+ G C + C + P GE + + C G+ G CED
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341
Query: 514 -RDHCAGSPCGN------GAACYTAQSDYYCHCAPGWTGKNCTQR--AARDRKTCSVLVE 564
G CG+ +C T D C C+ G+ G +C A CSV E
Sbjct: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCE 399
Query: 565 ESERCAEGMC-ANGGTCVREEGS 586
C EG+C G+C GS
Sbjct: 400 ----CPEGLCHPVSGSCQPGSGS 418
Score = 85.4 bits (202), Expect = 9e-16
Identities = 76/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNP------CAPQ--PCAHGTC 329
C H G C E +PD C C G++G C++ P C Q C HG
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--------PCLHGASCRDHLDGFTCECA 381
T G CD GW G G C+ G SC D + G C C+
Sbjct: 319 CEPDT--GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG-SC-DTVTG-DCVCS 373
Query: 382 DGWTGPAC 389
G+ GP+C
Sbjct: 374 AGYWGPSC 381
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
>AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein.
Length = 569
Score = 105 bits (252), Expect = 8e-22
Identities = 123/443 (27%), Positives = 158/443 (35%), Gaps = 86/443 (19%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+C G+ G C + C + P GE + + C G+ G CED
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341
Query: 514 -RDHCAGSPCGN------GAACYTAQSDYYCHCAPGWTGKNCTQR--AARDRKTCSVLVE 564
G CG+ +C T D C C+ G+ G +C A CSV E
Sbjct: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCE 399
Query: 565 ESERCAEGMC-ANGGTCVREEGS 586
C EG+C G+C GS
Sbjct: 400 ----CPEGLCHPVSGSCQPGSGS 418
Score = 85.4 bits (202), Expect = 9e-16
Identities = 76/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNP------CAPQ--PCAHGTC 329
C H G C E +PD C C G++G C++ P C Q C HG
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--------PCLHGASCRDHLDGFTCECA 381
T G CD GW G G C+ G SC D + G C C+
Sbjct: 319 CEPDT--GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG-SC-DTVTG-DCVCS 373
Query: 382 DGWTGPAC 389
G+ GP+C
Sbjct: 374 AGYWGPSC 381
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
>AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein.
Length = 830
Score = 105 bits (252), Expect = 8e-22
Identities = 123/443 (27%), Positives = 158/443 (35%), Gaps = 86/443 (19%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDV------DDCAPR-PCTNGGECVDLLNAYRCICPVGFSGTNCEDD 513
+C G+ G C + C + P GE + + C G+ G CED
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341
Query: 514 -RDHCAGSPCGN------GAACYTAQSDYYCHCAPGWTGKNCTQR--AARDRKTCSVLVE 564
G CG+ +C T D C C+ G+ G +C A CSV E
Sbjct: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCE 399
Query: 565 ESERCAEGMC-ANGGTCVREEGS 586
C EG+C G+C GS
Sbjct: 400 ----CPEGLCHPVSGSCQPGSGS 418
Score = 85.4 bits (202), Expect = 9e-16
Identities = 76/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNP------CAPQ--PCAHGTC 329
C H G C E +PD C C G++G C++ P C Q C HG
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 330 SLAGTTRGFTCTCDRGWGGXXXXXXXXXXASG--------PCLHGASCRDHLDGFTCECA 381
T G CD GW G G C+ G SC D + G C C+
Sbjct: 319 CEPDT--GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG-SC-DTVTG-DCVCS 373
Query: 382 DGWTGPAC 389
G+ GP+C
Sbjct: 374 AGYWGPSC 381
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 104 bits (249), Expect = 2e-21
Identities = 40/87 (45%), Positives = 51/87 (58%)
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA 518
F C C GYAG C +D+D+C P PC +GG C +L+ + C CP GF+G CE D + C
Sbjct: 2144 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECL 2203
Query: 519 GSPCGNGAACYTAQSDYYCHCAPGWTG 545
SPC NGA C + C C G+TG
Sbjct: 2204 QSPCKNGAICQNFPGSFNCVCKTGYTG 2230
Score = 90.6 bits (215), Expect = 2e-17
Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 422 YSCACLAGWTGRDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCA 480
+ C CL G+ G CE ++D+C C G TC +LV F C+C G+ GR C D+++C
Sbjct: 2144 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECL 2203
Query: 481 PRPCTNGGECVDLLNAYRCICPVGFSG 507
PC NG C + ++ C+C G++G
Sbjct: 2204 QSPCKNGAICQNFPGSFNCVCKTGYTG 2230
Score = 85.8 bits (203), Expect = 7e-16
Identities = 53/163 (32%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 308 SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGA 367
SGV E VD+ C HG C G+ C R S P + A
Sbjct: 2092 SGVKVESVDH----DSCVHGPCQNGGS-------CLRR---LAVSSVLKSRESLPVIIVA 2137
Query: 368 SCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACL 427
+ + L F C+C G+ G C D+DEC PC + C+N GG+SC+C
Sbjct: 2138 N--EPLQPFLCKCLPGYAGSWCEIDIDECLP--------SPCHSGGTCHNLVGGFSCSCP 2187
Query: 428 AGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAG 469
G+TGR CE ++++C C +GA C + F+C C GY G
Sbjct: 2188 DGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTG 2230
Score = 79.4 bits (187), Expect = 6e-14
Identities = 37/104 (35%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 338 FTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECS 397
F C C G+ G PC G +C + + GF+C C DG+TG AC D++EC
Sbjct: 2144 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINEC- 2202
Query: 398 GRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT---GRDCETN 438
PC N A C N G ++C C G+T G+ CE N
Sbjct: 2203 -------LQSPCKNGAICQNFPGSFNCVCKTGYTGVFGKHCELN 2239
Score = 66.9 bits (156), Expect = 3e-10
Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 299 YFCRCAEGFSGVDCERVDNPCAPQPC-AHGTC-SLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C+C G++G CE + C P PC + GTC +L G GF+C+C G+ G
Sbjct: 2144 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVG---GFSCSCPDGFTGRACERDIN 2200
Query: 357 XXASGPCLHGASCRDHLDGFTCECADGWTG 386
PC +GA C++ F C C G+TG
Sbjct: 2201 ECLQSPCKNGAICQNFPGSFNCVCKTGYTG 2230
Score = 65.7 bits (153), Expect = 8e-10
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
Query: 261 CTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA 320
C C + G C+ D++ C PC GGTC N + C C +GF+G CER N C
Sbjct: 2146 CKCLPGYAGSWCEIDIDEC-LPSPCHSGGTCHNLVGG-FSCSCPDGFTGRACERDINECL 2203
Query: 321 PQPCAHGTCSLAGTTRGFTCTCDRGWGG 348
PC +G F C C G+ G
Sbjct: 2204 QSPCKNGAI-CQNFPGSFNCVCKTGYTG 2230
Score = 62.9 bits (146), Expect = 5e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 225 RPGDCDCRPGWRGELCS----QCQPYPGCKHGYCNG--SSWDCTCDTNWGGILCDQDLNY 278
+P C C PG+ G C +C P P G C+ + C+C + G C++D+N
Sbjct: 2142 QPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINE 2201
Query: 279 CGTHEPCQHGGTCENTAPDQYFCRCAEGFSGV 310
C PC++G C+N P + C C G++GV
Sbjct: 2202 C-LQSPCKNGAICQN-FPGSFNCVCKTGYTGV 2231
Score = 60.5 bits (140), Expect = 3e-08
Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 36/137 (26%)
Query: 473 SLDVDDCAPRPCTNGGECV----------------------DLLNAYRCICPVGFSGTNC 510
S+D D C PC NGG C+ + L + C C G++G+ C
Sbjct: 2098 SVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWC 2157
Query: 511 EDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCA 570
E D D C SPC +G C+ + C C G+TG+ C + + C
Sbjct: 2158 EIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACER--------------DINECL 2203
Query: 571 EGMCANGGTCVREEGSW 587
+ C NG C GS+
Sbjct: 2204 QSPCKNGAICQNFPGSF 2220
Score = 58.4 bits (135), Expect = 1e-07
Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 618 AGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGW 677
+GGTC L G++C C +G TG CE ++ C SPC+NG C G + C C G+
Sbjct: 2171 SGGTC--HNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGY 2228
Query: 678 TG 679
TG
Sbjct: 2229 TG 2230
Score = 54.0 bits (124), Expect = 3e-06
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C C G G+ CE+ +D C SPC +GG C G + C C G+TG C
Sbjct: 2146 CKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRAC 2195
Score = 53.2 bits (122), Expect = 4e-06
Identities = 37/115 (32%), Positives = 50/115 (43%), Gaps = 12/115 (10%)
Query: 239 LCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILC-DQDLNY-------CGTHEPCQHGGT 290
L S + P K G C G + C + WG +LC +Q Y C +H PCQ+GG+
Sbjct: 2625 LASISKTDPSVKIG-CRGPNI-CASNPCWGDLLCINQWYAYRCVPPGDCASH-PCQNGGS 2681
Query: 291 CENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
CE + C C + +G CE V C C G AG+ G C +G
Sbjct: 2682 CEPGLHSGFTCSCPDSHTGRTCEMV-VACLGVLCPQGKVCKAGSPAGHVCVLSQG 2735
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/108 (30%), Positives = 42/108 (38%), Gaps = 18/108 (16%)
Query: 479 CAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTA-QSDYYC 537
CA PC C++ AYRC+ P CA PC NG +C S + C
Sbjct: 2645 CASNPCWGDLLCINQWYAYRCVPP------------GDCASHPCQNGGSCEPGLHSGFTC 2692
Query: 538 HCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEG 585
C TG+ C A VL + + C G A G CV +G
Sbjct: 2693 SCPDSHTGRTCEMVVA----CLGVLCPQGKVCKAGSPA-GHVCVLSQG 2735
Score = 43.2 bits (97), Expect = 0.005
Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 478 DCAPRPCTNGGEC-VDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAAC 528
DCA PC NGG C L + + C CP +G CE C G C G C
Sbjct: 2670 DCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCE-MVVACLGVLCPQGKVC 2720
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 359 ASGPCLHGASCRDHL-DGFTCECADGWTGPACAEDVDECSGRSMTEG 404
AS PC +G SC L GFTC C D TG C E V C G +G
Sbjct: 2672 ASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTC-EMVVACLGVLCPQG 2717
Score = 39.1 bits (87), Expect = 0.077
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 16/100 (16%)
Query: 198 CLPGWQGDNCEKPV--C-KEGCHPTHGRCDR---PGDCDCRPGWRGELC----SQCQPYP 247
CLPG+ G CE + C CH + G C C C G+ G C ++C P
Sbjct: 2148 CLPGYAGSWCEIDIDECLPSPCH-SGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSP 2206
Query: 248 GCKHG-YCNG--SSWDCTCDTNWGGILCDQ-DLNYCGTHE 283
CK+G C S++C C T + G+ +LN G E
Sbjct: 2207 -CKNGAICQNFPGSFNCVCKTGYTGVFGKHCELNSYGFEE 2245
Score = 37.5 bits (83), Expect = 0.24
Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 6/92 (6%)
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID-LVDD 458
S+ G GP N A N G C+ W C D + C +G +C L
Sbjct: 2634 SVKIGCRGP--NICASNPCWG--DLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGLHSG 2689
Query: 459 FHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
F C+C + GRTC + V C C G C
Sbjct: 2690 FTCSCPDSHTGRTCEM-VVACLGVLCPQGKVC 2720
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 651 CGSSPCRNGGRCVGG-SGWWMCECVAGWTGETCAVRVS 687
C S PC+NGG C G + C C TG TC + V+
Sbjct: 2671 CASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVA 2708
Score = 36.7 bits (81), Expect = 0.41
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 617 QAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGS 666
Q GG+C P L G+ C C + TG CE+ + C C G C GS
Sbjct: 2677 QNGGSCEPG-LHSGFTCSCPDSHTGRTCEMVV-ACLGVLCPQGKVCKAGS 2724
Score = 34.3 bits (75), Expect = 2.2
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 18/109 (16%)
Query: 222 RCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT 281
RC PGDC P CQ C+ G +G + C+C + G C+ + G
Sbjct: 2664 RCVPPGDCASHP---------CQNGGSCEPGLHSG--FTCSCPDSHTGRTCEMVVACLGV 2712
Query: 282 HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCS 330
C G C+ +P + C ++G E + P P G+C+
Sbjct: 2713 --LCPQGKVCKAGSPAGHVCVLSQG-----PEEISLPLWAVPAIVGSCA 2754
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 103 bits (247), Expect = 3e-21
Identities = 76/241 (31%), Positives = 101/241 (41%), Gaps = 37/241 (15%)
Query: 363 CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C+ + CR+ D C C DG+ A ED+DEC+ EG C C NT
Sbjct: 406 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-----EGR-HYCRENTMCVNT 459
Query: 419 AGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGYAGR-- 470
G + C C G+ D C T D+C T Q C A C + V +C C GY G
Sbjct: 460 PGSFMCICKTGYIRIDDYSC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 518
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNGAAC 528
TC D C NGG C+ A C CP GF+G +CE D D C+ C + A C
Sbjct: 519 TCKAFCKD----GCRNGGACIA---ANVCACPQGFTGPSCETDIDECSDGFVQCDSRANC 571
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG--MCANGGTCVREEGS 586
Y+C C G+ + ++C E+ + C G CAN C +G
Sbjct: 572 INLPGWYHCECRDGYHDNGMFSPSG---ESC----EDIDECGTGRHSCANDTICFNLDGG 624
Query: 587 W 587
+
Sbjct: 625 Y 625
Score = 101 bits (241), Expect = 2e-20
Identities = 71/233 (30%), Positives = 93/233 (39%), Gaps = 33/233 (14%)
Query: 363 CLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C C + F C C G+ +C E DEC C A C NT
Sbjct: 450 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEH-DECITNQHN------CDENALCFNTV 502
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
GG++C C G+TG C C +G CI CAC G+ G +C D+D+C
Sbjct: 503 GGHNCVCKPGYTGNGTTCKAF-CKDGCRNGGACIAANV---CACPQGFTGPSCETDIDEC 558
Query: 480 APR--PCTNGGECVDLLNAYRCICPVGF--------SGTNCEDDRDHCAGS--PCGNGAA 527
+ C + C++L Y C C G+ SG +CED D C C N
Sbjct: 559 SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI-DECGTGRHSCANDTI 617
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRK---TCSVLVEESERCAEGMCANG 577
C+ Y C C GKNCT D K + V E++RC+ C NG
Sbjct: 618 CFNLDGGYDCRCP---HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNG 667
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/209 (28%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 274 QDLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCAHGT 328
+D++ C G H C+ C NT P + C C G+ +D C D Q
Sbjct: 438 EDIDECAEGRHY-CRENTMCVNT-PGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDEN 495
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
T G C C G+ G C +G +C + C C G+TGP+
Sbjct: 496 ALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDGCRNGGAC---IAANVCACPQGFTGPS 550
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW--------TGRDCETNVD 440
C D+DECS +G + C + A C N G Y C C G+ +G CE ++D
Sbjct: 551 CETDIDECS-----DGFV-QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCE-DID 603
Query: 441 DC-TGQ--CLHGATCIDLVDDFHCACAAG 466
+C TG+ C + C +L + C C G
Sbjct: 604 ECGTGRHSCANDTICFNLDGGYDCRCPHG 632
Score = 55.6 bits (128), Expect = 8e-07
Identities = 89/372 (23%), Positives = 131/372 (35%), Gaps = 55/372 (14%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRG 237
C+ + YSCT + C+ NC++ C T G +C C+PG+ G
Sbjct: 467 CKTGYIRIDDYSCTEHDE--CITNQH--NCDENAL---CFNTVGG----HNCVCKPGYTG 515
Query: 238 ELCSQCQPY--PGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQHGGTCENT 294
+ C+ + GC++G ++ C C + G C+ D++ C C C N
Sbjct: 516 N-GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCIN- 573
Query: 295 APDQYFCRCAEGF--------SGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
P Y C C +G+ SG CE +D CA+ T G+ C C G
Sbjct: 574 LPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICF-NLDGGYDCRCPHG 632
Query: 346 WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
+G C+H + + + E D + +C C R M
Sbjct: 633 -----------KNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMC--RRMVCDC 678
Query: 406 LGPCVNAAACNNTAGGYSCACL--AGWT-GRDCETNVDDCTG-QCLHG-ATCIDL-VDDF 459
P V+ C S CL G T +T V +C +CL G C L D
Sbjct: 679 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 738
Query: 460 HCACAAGYAGRTCSLDV-DDCAPRPCTNG--GECVDLLNAYRCICPVGFSGTNCEDDRDH 516
C + C V D C N C+D +N R F+G++
Sbjct: 739 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVR------FTGSSWIKHGTE 792
Query: 517 CAGSPCGNGAAC 528
C C NG C
Sbjct: 793 CTLCQCKNGHIC 804
Score = 46.4 bits (105), Expect = 5e-04
Identities = 51/215 (23%), Positives = 72/215 (33%), Gaps = 40/215 (18%)
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN-----CEDDRDHCAGSP--CGNGAAC 528
D C+ R C C +L + C C GF CED D CA C C
Sbjct: 398 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDI-DECAEGRHYCRENTMC 456
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCAN---GGTCVREE 584
+ C C G+ + + C + C E +C N G CV +
Sbjct: 457 VNTPGSFMCICKTGYI--RIDDYSCTEHDEC---ITNQHNCDENALCFNTVGGHNCVCKP 511
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
G + + GG C+ + + C C +G TG C
Sbjct: 512 GY---------------TGNGTTCKAFCKDGCRNGGACIAANV-----CACPQGFTGPSC 551
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
E +D C G C + C+ GW+ CEC G+
Sbjct: 552 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 586
Score = 40.3 bits (90), Expect = 0.033
Identities = 40/165 (24%), Positives = 55/165 (33%), Gaps = 23/165 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGT 579
C + C C C G+ RA R+ + E+ + CAEG C
Sbjct: 406 CMENSICRNLNDRAVCSCRDGF-------RALRED---NAYCEDIDECAEGRHYCRENTM 455
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV GS+ S C + G C C+ G
Sbjct: 456 CVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTV--GGHNCVCKPGY 513
Query: 640 TG--ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
TG C+ C CRNGG C+ + +C C G+TG +C
Sbjct: 514 TGNGTTCKA---FCKDG-CRNGGACIAAN---VCACPQGFTGPSC 551
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 103 bits (247), Expect = 3e-21
Identities = 76/241 (31%), Positives = 101/241 (41%), Gaps = 37/241 (15%)
Query: 363 CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C+ + CR+ D C C DG+ A ED+DEC+ EG C C NT
Sbjct: 407 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-----EGR-HYCRENTMCVNT 460
Query: 419 AGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGYAGR-- 470
G + C C G+ D C T D+C T Q C A C + V +C C GY G
Sbjct: 461 PGSFMCICKTGYIRIDDYSC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 519
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNGAAC 528
TC D C NGG C+ A C CP GF+G +CE D D C+ C + A C
Sbjct: 520 TCKAFCKD----GCRNGGACIA---ANVCACPQGFTGPSCETDIDECSDGFVQCDSRANC 572
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG--MCANGGTCVREEGS 586
Y+C C G+ + ++C E+ + C G CAN C +G
Sbjct: 573 INLPGWYHCECRDGYHDNGMFSPSG---ESC----EDIDECGTGRHSCANDTICFNLDGG 625
Query: 587 W 587
+
Sbjct: 626 Y 626
Score = 101 bits (241), Expect = 2e-20
Identities = 71/233 (30%), Positives = 93/233 (39%), Gaps = 33/233 (14%)
Query: 363 CLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C C + F C C G+ +C E DEC C A C NT
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEH-DECITNQHN------CDENALCFNTV 503
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
GG++C C G+TG C C +G CI CAC G+ G +C D+D+C
Sbjct: 504 GGHNCVCKPGYTGNGTTCKAF-CKDGCRNGGACIAANV---CACPQGFTGPSCETDIDEC 559
Query: 480 APR--PCTNGGECVDLLNAYRCICPVGF--------SGTNCEDDRDHCAGS--PCGNGAA 527
+ C + C++L Y C C G+ SG +CED D C C N
Sbjct: 560 SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI-DECGTGRHSCANDTI 618
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRK---TCSVLVEESERCAEGMCANG 577
C+ Y C C GKNCT D K + V E++RC+ C NG
Sbjct: 619 CFNLDGGYDCRCP---HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNG 668
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/209 (28%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 274 QDLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCAHGT 328
+D++ C G H C+ C NT P + C C G+ +D C D Q
Sbjct: 439 EDIDECAEGRHY-CRENTMCVNT-PGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDEN 496
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
T G C C G+ G C +G +C + C C G+TGP+
Sbjct: 497 ALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDGCRNGGAC---IAANVCACPQGFTGPS 551
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW--------TGRDCETNVD 440
C D+DECS +G + C + A C N G Y C C G+ +G CE ++D
Sbjct: 552 CETDIDECS-----DGFV-QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCE-DID 604
Query: 441 DC-TGQ--CLHGATCIDLVDDFHCACAAG 466
+C TG+ C + C +L + C C G
Sbjct: 605 ECGTGRHSCANDTICFNLDGGYDCRCPHG 633
Score = 55.6 bits (128), Expect = 8e-07
Identities = 89/372 (23%), Positives = 131/372 (35%), Gaps = 55/372 (14%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRG 237
C+ + YSCT + C+ NC++ C T G +C C+PG+ G
Sbjct: 468 CKTGYIRIDDYSCTEHDE--CITNQH--NCDENAL---CFNTVGG----HNCVCKPGYTG 516
Query: 238 ELCSQCQPY--PGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQHGGTCENT 294
+ C+ + GC++G ++ C C + G C+ D++ C C C N
Sbjct: 517 N-GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCIN- 574
Query: 295 APDQYFCRCAEGF--------SGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
P Y C C +G+ SG CE +D CA+ T G+ C C G
Sbjct: 575 LPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICF-NLDGGYDCRCPHG 633
Query: 346 WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
+G C+H + + + E D + +C C R M
Sbjct: 634 -----------KNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMC--RRMVCDC 679
Query: 406 LGPCVNAAACNNTAGGYSCACL--AGWT-GRDCETNVDDCTG-QCLHG-ATCIDL-VDDF 459
P V+ C S CL G T +T V +C +CL G C L D
Sbjct: 680 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 739
Query: 460 HCACAAGYAGRTCSLDV-DDCAPRPCTNG--GECVDLLNAYRCICPVGFSGTNCEDDRDH 516
C + C V D C N C+D +N R F+G++
Sbjct: 740 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVR------FTGSSWIKHGTE 793
Query: 517 CAGSPCGNGAAC 528
C C NG C
Sbjct: 794 CTLCQCKNGHIC 805
Score = 46.4 bits (105), Expect = 5e-04
Identities = 51/215 (23%), Positives = 72/215 (33%), Gaps = 40/215 (18%)
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN-----CEDDRDHCAGSP--CGNGAAC 528
D C+ R C C +L + C C GF CED D CA C C
Sbjct: 399 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDI-DECAEGRHYCRENTMC 457
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCAN---GGTCVREE 584
+ C C G+ + + C + C E +C N G CV +
Sbjct: 458 VNTPGSFMCICKTGYI--RIDDYSCTEHDEC---ITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
G + + GG C+ + + C C +G TG C
Sbjct: 513 GY---------------TGNGTTCKAFCKDGCRNGGACIAANV-----CACPQGFTGPSC 552
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
E +D C G C + C+ GW+ CEC G+
Sbjct: 553 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 40.3 bits (90), Expect = 0.033
Identities = 40/165 (24%), Positives = 55/165 (33%), Gaps = 23/165 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGT 579
C + C C C G+ RA R+ + E+ + CAEG C
Sbjct: 407 CMENSICRNLNDRAVCSCRDGF-------RALRED---NAYCEDIDECAEGRHYCRENTM 456
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV GS+ S C + G C C+ G
Sbjct: 457 CVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTV--GGHNCVCKPGY 514
Query: 640 TG--ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
TG C+ C CRNGG C+ + +C C G+TG +C
Sbjct: 515 TGNGTTCKA---FCKDG-CRNGGACIAAN---VCACPQGFTGPSC 552
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 103 bits (247), Expect = 3e-21
Identities = 76/241 (31%), Positives = 101/241 (41%), Gaps = 37/241 (15%)
Query: 363 CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAAACNNT 418
C+ + CR+ D C C DG+ A ED+DEC+ EG C C NT
Sbjct: 407 CMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-----EGR-HYCRENTMCVNT 460
Query: 419 AGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGYAGR-- 470
G + C C G+ D C T D+C T Q C A C + V +C C GY G
Sbjct: 461 PGSFMCICKTGYIRIDDYSC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGT 519
Query: 471 TCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNGAAC 528
TC D C NGG C+ A C CP GF+G +CE D D C+ C + A C
Sbjct: 520 TCKAFCKD----GCRNGGACIA---ANVCACPQGFTGPSCETDIDECSDGFVQCDSRANC 572
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG--MCANGGTCVREEGS 586
Y+C C G+ + ++C E+ + C G CAN C +G
Sbjct: 573 INLPGWYHCECRDGYHDNGMFSPSG---ESC----EDIDECGTGRHSCANDTICFNLDGG 625
Query: 587 W 587
+
Sbjct: 626 Y 626
Score = 101 bits (241), Expect = 2e-20
Identities = 71/233 (30%), Positives = 93/233 (39%), Gaps = 33/233 (14%)
Query: 363 CLHGASCRDHLDGFTCECADGWT---GPACAEDVDECSGRSMTEGALGPCVNAAACNNTA 419
C C + F C C G+ +C E DEC C A C NT
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEH-DECITNQHN------CDENALCFNTV 503
Query: 420 GGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDC 479
GG++C C G+TG C C +G CI CAC G+ G +C D+D+C
Sbjct: 504 GGHNCVCKPGYTGNGTTCKAF-CKDGCRNGGACIAANV---CACPQGFTGPSCETDIDEC 559
Query: 480 APR--PCTNGGECVDLLNAYRCICPVGF--------SGTNCEDDRDHCAGS--PCGNGAA 527
+ C + C++L Y C C G+ SG +CED D C C N
Sbjct: 560 SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDI-DECGTGRHSCANDTI 618
Query: 528 CYTAQSDYYCHCAPGWTGKNCTQRAARDRK---TCSVLVEESERCAEGMCANG 577
C+ Y C C GKNCT D K + V E++RC+ C NG
Sbjct: 619 CFNLDGGYDCRCP---HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNG 668
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/209 (28%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 274 QDLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD---CERVDNPCAPQPCAHGT 328
+D++ C G H C+ C NT P + C C G+ +D C D Q
Sbjct: 439 EDIDECAEGRHY-CRENTMCVNT-PGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDEN 496
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
T G C C G+ G C +G +C + C C G+TGP+
Sbjct: 497 ALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDGCRNGGAC---IAANVCACPQGFTGPS 551
Query: 389 CAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW--------TGRDCETNVD 440
C D+DECS +G + C + A C N G Y C C G+ +G CE ++D
Sbjct: 552 CETDIDECS-----DGFV-QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCE-DID 604
Query: 441 DC-TGQ--CLHGATCIDLVDDFHCACAAG 466
+C TG+ C + C +L + C C G
Sbjct: 605 ECGTGRHSCANDTICFNLDGGYDCRCPHG 633
Score = 55.6 bits (128), Expect = 8e-07
Identities = 89/372 (23%), Positives = 131/372 (35%), Gaps = 55/372 (14%)
Query: 178 CRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRG 237
C+ + YSCT + C+ NC++ C T G +C C+PG+ G
Sbjct: 468 CKTGYIRIDDYSCTEHDE--CITNQH--NCDENAL---CFNTVGG----HNCVCKPGYTG 516
Query: 238 ELCSQCQPY--PGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGT-HEPCQHGGTCENT 294
+ C+ + GC++G ++ C C + G C+ D++ C C C N
Sbjct: 517 N-GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCIN- 574
Query: 295 APDQYFCRCAEGF--------SGVDCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRG 345
P Y C C +G+ SG CE +D CA+ T G+ C C G
Sbjct: 575 LPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICF-NLDGGYDCRCPHG 633
Query: 346 WGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGA 405
+G C+H + + + E D + +C C R M
Sbjct: 634 -----------KNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMC--RRMVCDC 679
Query: 406 LGPCVNAAACNNTAGGYSCACL--AGWT-GRDCETNVDDCTG-QCLHG-ATCIDL-VDDF 459
P V+ C S CL G T +T V +C +CL G C L D
Sbjct: 680 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 739
Query: 460 HCACAAGYAGRTCSLDV-DDCAPRPCTNG--GECVDLLNAYRCICPVGFSGTNCEDDRDH 516
C + C V D C N C+D +N R F+G++
Sbjct: 740 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVR------FTGSSWIKHGTE 793
Query: 517 CAGSPCGNGAAC 528
C C NG C
Sbjct: 794 CTLCQCKNGHIC 805
Score = 46.4 bits (105), Expect = 5e-04
Identities = 51/215 (23%), Positives = 72/215 (33%), Gaps = 40/215 (18%)
Query: 477 DDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN-----CEDDRDHCAGSP--CGNGAAC 528
D C+ R C C +L + C C GF CED D CA C C
Sbjct: 399 DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDI-DECAEGRHYCRENTMC 457
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG-MCAN---GGTCVREE 584
+ C C G+ + + C + C E +C N G CV +
Sbjct: 458 VNTPGSFMCICKTGYI--RIDDYSCTEHDEC---ITNQHNCDENALCFNTVGGHNCVCKP 512
Query: 585 GSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGRTGALC 644
G + + GG C+ + + C C +G TG C
Sbjct: 513 GY---------------TGNGTTCKAFCKDGCRNGGACIAANV-----CACPQGFTGPSC 552
Query: 645 ELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAGW 677
E +D C G C + C+ GW+ CEC G+
Sbjct: 553 ETDIDECSDGFVQCDSRANCINLPGWYHCECRDGY 587
Score = 40.3 bits (90), Expect = 0.033
Identities = 40/165 (24%), Positives = 55/165 (33%), Gaps = 23/165 (13%)
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGM--CANGGT 579
C + C C C G+ RA R+ + E+ + CAEG C
Sbjct: 407 CMENSICRNLNDRAVCSCRDGF-------RALRED---NAYCEDIDECAEGRHYCRENTM 456
Query: 580 CVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWACGCREGR 639
CV GS+ S C + G C C+ G
Sbjct: 457 CVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTV--GGHNCVCKPGY 514
Query: 640 TG--ALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
TG C+ C CRNGG C+ + +C C G+TG +C
Sbjct: 515 TGNGTTCKA---FCKDG-CRNGGACIAAN---VCACPQGFTGPSC 552
>AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.
Length = 1097
Score = 103 bits (247), Expect = 3e-21
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 435 CETNVDDCT-GQCLHGATCIDLVDD-FHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVD 492
C D C C HG +C L + C C + + GR C ++ C P PC NGG C
Sbjct: 526 CVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDP 585
Query: 493 LLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQR 551
+ N + C C G +G CE+D + C C NG +C + C+C PG+ G+ C R
Sbjct: 586 IGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLR 644
Score = 81.0 bits (191), Expect = 2e-14
Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Query: 362 PCLHGASCRD-HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAG 420
PC HG SC G+ C C +TG C ++ C PC N +C+
Sbjct: 537 PCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPN--------PCRNGGSCDPIGN 588
Query: 421 GYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSL 474
+ C C AG TG CE ++++C +C +G +C+++ F C C GY G+ C L
Sbjct: 589 TFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGL 643
Score = 78.2 bits (184), Expect = 1e-13
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 3/107 (2%)
Query: 284 PCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GTCSLAGTTRGFTCTC 342
PCQHGG+C Y C C F+G +CE C P PC + G+C G T F C C
Sbjct: 537 PCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNT--FICNC 594
Query: 343 DRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC 389
G G C +G SC + F C C G+ G C
Sbjct: 595 KAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYC 641
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/117 (34%), Positives = 53/117 (45%), Gaps = 15/117 (12%)
Query: 472 CSLDVDDCAPRPCTNGGECVDLLNA-YRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYT 530
C L D C PC +GG C L + Y+C C F+G NCE + C +PC NG +C
Sbjct: 526 CVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDP 585
Query: 531 AQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+ + C+C G TG C E+ C C NGG+CV GS+
Sbjct: 586 IGNTFICNCKAGLTGVTCE--------------EDINECEREECENGGSCVNVFGSF 628
Score = 74.9 bits (176), Expect = 1e-12
Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 8/124 (6%)
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRD 371
C + C PC HG + G+ CTC + G PC +G SC
Sbjct: 526 CVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDP 585
Query: 372 HLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ F C C G TG C ED++EC C N +C N G + C C G+
Sbjct: 586 IGNTFICNCKAGLTGVTCEEDINECEREE--------CENGGSCVNVFGSFLCNCTPGYV 637
Query: 432 GRDC 435
G+ C
Sbjct: 638 GQYC 641
Score = 61.7 bits (143), Expect = 1e-08
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG+C P + + C C+ G TG CE ++ C C NGG CV G ++C C G+
Sbjct: 580 GGSCDP--IGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYV 637
Query: 679 GETCAVR 685
G+ C +R
Sbjct: 638 GQYCGLR 644
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 9/114 (7%)
Query: 205 DNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQ----CQPYPGCKHGYCN--GSS 258
D C++ C+ G T G C C + G C C P P G C+ G++
Sbjct: 531 DACKRSPCQHGGSCT-GLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNT 589
Query: 259 WDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDC 312
+ C C G+ C++D+N C E C++GG+C N + C C G+ G C
Sbjct: 590 FICNCKAGLTGVTCEEDINEC-EREECENGGSCVNVF-GSFLCNCTPGYVGQYC 641
Score = 59.7 bits (138), Expect = 5e-08
Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 617 QAGGTCLPSALPPG-WACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVA 675
Q GG+C + LP G + C C TG CE + C +PCRNGG C ++C C A
Sbjct: 539 QHGGSC--TGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICNCKA 596
Query: 676 GWTGETC 682
G TG TC
Sbjct: 597 GLTGVTC 603
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 644 CELSLDLCGSSPCRNGGRCVG-GSGWWMCECVAGWTGETCAVRVS 687
C L D C SPC++GG C G SG + C C++ +TG C ++
Sbjct: 526 CVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEIT 570
>BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein.
Length = 600
Score = 103 bits (246), Expect = 4e-21
Identities = 46/128 (35%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Query: 440 DDCTGQ-CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYR 498
D+C C +G +C +L + C C AG+ G C +VD C PC +GG C AY
Sbjct: 28 DECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 87
Query: 499 CICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
C+CP F G +CE D C SPCG C + + C C G+TG++C +
Sbjct: 88 CVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTAL 147
Query: 559 CSVLVEES 566
VEES
Sbjct: 148 KMERVEES 155
Score = 88.6 bits (210), Expect = 1e-16
Identities = 38/104 (36%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAG 466
PC N +C N G Y C C AG+ G CET VD C + C HG C + C C
Sbjct: 34 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 93
Query: 467 YAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
+ G C D C PC G C+ ++ C C VG++G +C
Sbjct: 94 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 137
Score = 79.0 bits (186), Expect = 8e-14
Identities = 42/125 (33%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 270 ILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAH-GT 328
+LC + + C H PC++GG+C N P Y CRC GF GV CE + C PC H G
Sbjct: 22 LLC-AERDECRAH-PCRNGGSCRNL-PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGR 78
Query: 329 CSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPA 388
C G + C C + G S PC C +C C G+TG
Sbjct: 79 CESGG--GAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGED 136
Query: 389 CAEDV 393
CA+++
Sbjct: 137 CAKEL 141
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 9/116 (7%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGG 421
PC +G SCR+ + C C G+ G C +VD C PC + C + G
Sbjct: 34 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDS--------SPCQHGGRCESGGGA 85
Query: 422 YSCACLAGWTGRDCETNVDDC-TGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDV 476
Y C C + G CET D C + C C+ C C GY G C+ ++
Sbjct: 86 YLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 141
Score = 64.1 bits (149), Expect = 2e-09
Identities = 27/64 (42%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWT 678
GG+C LP + C C G G CE +D C SSPC++GGRC G G ++C C +
Sbjct: 38 GGSC--RNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFF 95
Query: 679 GETC 682
G C
Sbjct: 96 GYHC 99
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTC 378
C PC +G S + C C G+ G S PC HG C + C
Sbjct: 30 CRAHPCRNGG-SCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLC 88
Query: 379 ECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDC 435
C + + G C D C PC C + G +SC C G+TG DC
Sbjct: 89 VCPESFFGYHCETVSDPCFS--------SPCGGRGYCLASNGSHSCTCKVGYTGEDC 137
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 6/123 (4%)
Query: 561 VLVEESERCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGG 620
+L E + C C NGG+C G++ ++ Q GG
Sbjct: 22 LLCAERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPC----QHGG 77
Query: 621 TCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGE 680
C + C C E G CE D C SSPC G C+ +G C C G+TGE
Sbjct: 78 RCESGG--GAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE 135
Query: 681 TCA 683
CA
Sbjct: 136 DCA 138
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 513 DRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC-TQRAARDRKTCSVLVEESERCAE 571
+RD C PC NG +C Y C C G+ G +C T+ A D C + RC
Sbjct: 26 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPC----QHGGRCES 81
Query: 572 G 572
G
Sbjct: 82 G 82
Score = 43.6 bits (98), Expect = 0.004
Identities = 15/52 (28%), Positives = 26/52 (50%)
Query: 516 HCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESE 567
+C+ +PC NG C + C C PG+ G+ C + + C+ L E++
Sbjct: 512 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETK 563
Score = 43.2 bits (97), Expect = 0.005
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 640 TGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRV 686
T LC D C + PCRNGG C G ++C C AG+ G C V
Sbjct: 20 TPLLCA-ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV 65
Score = 43.2 bits (97), Expect = 0.005
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 478 DCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE 511
+C+ PC NGG CV +A+ C C GF G CE
Sbjct: 512 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 545
Score = 40.7 bits (91), Expect = 0.025
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 651 CGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
C +PC+NGG CV G+ C+C G+ G C
Sbjct: 513 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 544
Score = 39.5 bits (88), Expect = 0.058
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 281 THEPCQHGGTCENTAPDQYFCRCAEGFSGVDCE----RVDNPC 319
+ PCQ+GGTC A D + C C GF G CE +V PC
Sbjct: 514 SENPCQNGGTCVPGA-DAHSCDCGPGFKGRRCELACIKVSRPC 555
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 446 CLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCT 485
C +G TC+ D C C G+ GR C L + RPCT
Sbjct: 518 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPCT 556
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 408 PCVNAAACNNTAGGYSCACLAGWTGRDCE 436
PC N C A +SC C G+ GR CE
Sbjct: 517 PCQNGGTCVPGADAHSCDCGPGFKGRRCE 545
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 103 bits (246), Expect = 4e-21
Identities = 122/429 (28%), Positives = 160/429 (37%), Gaps = 71/429 (16%)
Query: 301 CRCAEGFSGVDCERVD-NPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWG----GXXXXX 353
C G D R D N CA P C +G C T F C C G+ G
Sbjct: 175 CVSRRAVPGPDDSREDVNECAENPGVCTNGVC--VNTDGSFRCECPFGYSLDFTGINCVD 232
Query: 354 XXXXXASGPCLHGASCRDHLDGFTCECADGWTGPAC--AEDVDECSGRSMTEGALGPCVN 411
PC G +C + + GF C CADG+ ED+DECS L P +
Sbjct: 233 TDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMTCEDIDECS--------LNPLLC 283
Query: 412 AAACNNTAGGYSCACLAGWTGRD----CETNVDDCT-GQ--C-LHGATCIDLVDDFHCAC 463
A C+NT G Y C C AG+T R+ C +VD+C GQ C G C +L+ F C C
Sbjct: 284 AFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVC 342
Query: 464 AAGY-----AGRTCSLDVDDCAPRP--CTNGGECVDLLNAYRCICPVGFSG----TNCED 512
G +G C+ D ++C +P C NG CV+ ++RC C GF T C D
Sbjct: 343 PPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTAGSFRCDCDEGFQPSPTLTECHD 400
Query: 513 DRD-----HCAGSPCGNGAACYTAQSDYYCHC--APGWTGKNC----TQRAARDRKTC-- 559
R + C + ++ A + C C GW G C + RK C
Sbjct: 401 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 459
Query: 560 -SVLVEESE-----RCAEGMCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXX 613
S E R +CA+ G C+ GS+R D+
Sbjct: 460 GSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFR---CHCQAGYTPDATATTCLDMDEC 515
Query: 614 XXXQAGGTCLPSALPPGWACGCREG----RTGALCELSLDLCGSSPCRNGGRCVGGSGWW 669
T L + C C G G C+ LD C S CV G +
Sbjct: 516 SQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAF 574
Query: 670 MCECVAGWT 678
C C G+T
Sbjct: 575 TCRCPPGFT 583
Score = 88.6 bits (210), Expect = 1e-16
Identities = 79/256 (30%), Positives = 102/256 (39%), Gaps = 38/256 (14%)
Query: 312 CERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS---GPCLHGAS 368
C ++ P P A AG T C R G + G C +G
Sbjct: 148 CPKLSTPPRPAAAAVRGLGRAGETPA-NCVSRRAVPGPDDSREDVNECAENPGVCTNGV- 205
Query: 369 CRDHLDGFTCECADGW----TGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
C + F CEC G+ TG C D DECS PC C N GG+ C
Sbjct: 206 CVNTDGSFRCECPFGYSLDFTGINCV-DTDECSVGH-------PC-GQGTCTNVIGGFEC 256
Query: 425 ACLAGWTG---RDCETNVDDCT-GQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDV 476
AC G+ CE ++D+C+ L C + + C C AGY G C DV
Sbjct: 257 ACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DV 314
Query: 477 DDCAP--RPC-TNGGECVDLLNAYRCICPVGF-----SGTNCEDDRD-HCAGSPCGNGAA 527
D+CA + C G EC +L+ + C+CP G SG C DD + H C NG
Sbjct: 315 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 374
Query: 528 CYTAQSDYYCHCAPGW 543
TA S + C C G+
Sbjct: 375 VNTAGS-FRCDCDEGF 389
Score = 84.6 bits (200), Expect = 2e-15
Identities = 68/242 (28%), Positives = 99/242 (40%), Gaps = 40/242 (16%)
Query: 324 CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX-----XXASGPCLHGASCRDHLDGFTC 378
CAHG C + F C C G+ PC C++ F C
Sbjct: 480 CAHGEC--INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF--LCKNTKGSFLC 535
Query: 379 ECADGWT----GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRD 434
C G+ G C +D+DEC+ R L C NT G ++C C G+T
Sbjct: 536 SCPRGYLLEEDGRTC-KDLDECTSRQHNCQFL--------CVNTVGAFTCRCPPGFTQHH 586
Query: 435 CET-NVDDCTG--QCLHGATCIDLVDDFHCACAAGYAGRTC---SLDVDDCAPRPCTNGG 488
+V++C G +C HG C + + + C+C G+ + +D ++CA P T G
Sbjct: 587 QACFDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS 644
Query: 489 -ECVDLLNAYRCICPVGFSGT----NCEDDRDHCAG--SPCGNGAACYTAQSDYYCHCAP 541
C + L +RC+CP GF C+ D D CAG PC +C + C C
Sbjct: 645 ASCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPC--SYSCANTPGGFLCGCPQ 701
Query: 542 GW 543
G+
Sbjct: 702 GY 703
Score = 83.4 bits (197), Expect = 4e-15
Identities = 117/450 (26%), Positives = 161/450 (35%), Gaps = 83/450 (18%)
Query: 204 GDNC-EKPVCKEGCHPT-HGRCDRP---GDCDCRPGWRGELCSQCQPYPGCKHG------ 252
G NC + C G HP G C +C C G+ L C+ C
Sbjct: 227 GINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 285
Query: 253 YCNGS--SWDCTCDTNW----GGILCDQDLNYCGTHEPCQH--GGTCENTAPDQYFCRCA 304
C+ + S+ CTC + G +C +D++ C + H G C+N + C C
Sbjct: 286 RCHNTEGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLI-GTFACVCP 343
Query: 305 EGF-----SGVDCERVDNPCAPQP--CAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
G SG C DN C QP C +G C T F C CD G+
Sbjct: 344 PGMRPLPGSGEGCTD-DNECHAQPDLCVNGRC--VNTAGSFRCDCDEGFQPSPTLTECHD 400
Query: 358 XASGP---------CLHGASCRDHLDGFTCECADG--WTGPACA---------------- 390
GP C +S + + C C G W GP C
Sbjct: 401 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPH 459
Query: 391 EDVDECSGRSMTE-GALGPCVNAAACNNTAGGYSCACLAGWTGRDCET---NVDDCTGQC 446
GR + E L C N+ G + C C AG+T T ++D+C+ Q
Sbjct: 460 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECS-QV 518
Query: 447 LHGAT--CIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCI 500
T C + F C+C GY GRTC D+D+C R CV+ + A+ C
Sbjct: 519 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCR 577
Query: 501 CPVGFSGTN--CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKT 558
CP GF+ + C D + C +G C Y C C G+T ++ D
Sbjct: 578 CPPGFTQHHQACFDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFT-QHSQWAQCVDENE 634
Query: 559 CSVLVEESERCAEGMCAN---GGTCVREEG 585
C++ C C N G CV G
Sbjct: 635 CAL---SPPTCGSASCRNTLGGFRCVCPSG 661
Score = 81.0 bits (191), Expect = 2e-14
Identities = 71/241 (29%), Positives = 101/241 (41%), Gaps = 39/241 (16%)
Query: 249 CKHGYCNGS--SWDCTCDTNWG----GILCDQDLNYCG-THEPCQHGGTCENTAPDQYFC 301
C HG C S S+ C C + C D++ C +PC C+NT + C
Sbjct: 480 CAHGECINSLGSFRCHCQAGYTPDATATTC-LDMDECSQVPKPCTF--LCKNTK-GSFLC 535
Query: 302 RCAEGF----SGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXX 357
C G+ G C+ +D + Q C T FTC C G+
Sbjct: 536 SCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC--VNTVGAFTCRCPPGFTQHHQACFDVN 593
Query: 358 XASGP--CLHGASCRDHLDGFTCECADGWTGPA-CAEDVDECSGRSMTEGALG-PCVNAA 413
GP C HG C++ L G+ C C G+T + A+ VDE E AL P +A
Sbjct: 594 ECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE------NECALSPPTCGSA 645
Query: 414 ACNNTAGGYSCACLAGWTGRD----CETNVDDCTGQ---CLHGATCIDLVDDFHCACAAG 466
+C NT GG+ C C +G+ C+ +VD+C G+ C + +C + F C C G
Sbjct: 646 SCRNTLGGFRCVCPSGFDFDQALGGCQ-DVDECAGRRGPCSY--SCANTPGGFLCGCPQG 702
Query: 467 Y 467
Y
Sbjct: 703 Y 703
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 100 bits (240), Expect = 2e-20
Identities = 98/365 (26%), Positives = 148/365 (40%), Gaps = 63/365 (17%)
Query: 229 CDCRPGWRGELCSQCQPYPGCKHGYCNGS----------SWDCTCDTNWGGILCDQDLNY 278
C C+PG++GE QC C++ Y NG ++ CTC + G + D +
Sbjct: 59 CLCKPGYKGE-GKQCGDIDECENDYYNGGCVHECINIPGNYRCTC---FDGFMLAHDGHN 114
Query: 279 CGTHEPCQ-HGGTCEN---TAPDQYFCRCAEGFSGVDCER--VDNPCAPQPCA---HGTC 329
C + CQ + G C+ A Y C+C GF D + + C HG
Sbjct: 115 CLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCA 174
Query: 330 SLAGTTR--GFTCTCDRGWG---GXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGW 384
+ T G C C G+ +G C H SC D G TC C +
Sbjct: 175 HICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH--SCEDTDTGPTCGCHQKY 232
Query: 385 TGPACAED-VDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNV 439
+ ++ C+ + G C C +TA G C+C G+T G+ C+ ++
Sbjct: 233 APHSDGRTCIETCAVNN------GGCDRT--CKDTATGVRCSCPVGFTLQPDGKTCK-DI 283
Query: 440 DDC---TGQCLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCA-PRPCTNGGECV 491
++C G C H C + V F C C GY RTC D+D+C+ R C + C+
Sbjct: 284 NECLVNNGGCDH--FCRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDH--ICI 338
Query: 492 DLLNAYRCICPVGFS--GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPG----WTG 545
+ +++C+C G+ GT D D C+ S C + Y C C PG W
Sbjct: 339 NSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNR 398
Query: 546 KNCTQ 550
K+C +
Sbjct: 399 KDCVE 403
Score = 85.4 bits (202), Expect = 9e-16
Identities = 93/351 (26%), Positives = 135/351 (38%), Gaps = 64/351 (18%)
Query: 198 CLPGWQG--------DNCEKPVCKEGCHPTHGRCDRPGD--CDCRPGWR----GELC--- 240
C PG++G D CE GC H + PG+ C C G+ G C
Sbjct: 61 CKPGYKGEGKQCGDIDECENDYYNGGC--VHECINIPGNYRCTCFDGFMLAHDGHNCLDV 118
Query: 241 SQCQPYPG-CKHGYCNG-SSWDCTCDTNW----GGILC----DQDLNYCGTHEPCQHGGT 290
+CQ G C+ N S++C C + + C ++ +N C H
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--I 176
Query: 291 CENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGT--C--SLAGTTRGFTCTCDRGW 346
C T C C GF D + C C +G C S T G TC C + +
Sbjct: 177 CRETPKGGVACDCRPGF---DLAQNQKDCT-LTCNYGNGGCQHSCEDTDTGPTCGCHQKY 232
Query: 347 GGXXXXXXXXXXAS---GPCLHGASCRDHLDGFTCECADGWT----GPACAEDVDECSGR 399
+ G C +C+D G C C G+T G C +D++EC
Sbjct: 233 APHSDGRTCIETCAVNNGGC--DRTCKDTATGVRCSCPVGFTLQPDGKTC-KDINECLVN 289
Query: 400 SMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQCLHGATCIDL 455
+ G C + C NT G + C C G+ R C+ ++D+C+ + CI+
Sbjct: 290 N------GGCDHF--CRNTVGSFECGCRKGYKLLTDERTCQ-DIDECSFERTCDHICINS 340
Query: 456 VDDFHCACAAGYA--GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVG 504
F C C GY G T DVD+C+ + CV+ +Y C+CP G
Sbjct: 341 PGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 81.0 bits (191), Expect = 2e-14
Identities = 95/337 (28%), Positives = 132/337 (39%), Gaps = 65/337 (19%)
Query: 275 DLNYC--GTHEPCQHGGTCENTAPDQYFCRCAEGFSGV-----DCERVDNPCAPQPCAHG 327
D++ C GT + C C+N AP Y C C G+ G D + +N C H
Sbjct: 33 DVDECSEGTDD-CHIDAICQN-APKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHE 90
Query: 328 TCSLAGTTRGFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECAD 382
++ G R CTC G+ G +G C C + + + C+C
Sbjct: 91 CINIPGNYR---CTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYECQCHS 145
Query: 383 GWTGPACAEDVDECSGRSMTEGALGPCVN-----AAACNNTA-GGYSCACLAGWTGRDCE 436
G+ +++ C RS EG C+N A C T GG +C C G+ D
Sbjct: 146 GFF---LSDNQHTCIHRS-NEGM--NCMNKDHGCAHICRETPKGGVACDCRPGF---DLA 196
Query: 437 TNVDDCTGQCLHGA-----TCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNG 487
N DCT C +G +C D C C YA GRTC ++ CA NG
Sbjct: 197 QNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTC---IETCA---VNNG 250
Query: 488 G---ECVDLLNAYRCICPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCA 540
G C D RC CPVGF+ G C+D + C + G C + C C
Sbjct: 251 GCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE-CLVNNGGCDHFCRNTVGSFECGCR 309
Query: 541 PGWTGKNCTQRAARDRKTCSVLVEES-ERCAEGMCAN 576
G+ + D +TC + E S ER + +C N
Sbjct: 310 KGY-------KLLTDERTCQDIDECSFERTCDHICIN 339
Score = 42.3 bits (95), Expect = 0.008
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 9/93 (9%)
Query: 465 AGYAGRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGTNCE-DDRDHCAGSP 521
AG +G S+DVD+C+ C C + +Y+C+C G+ G + D D C
Sbjct: 23 AGGSGLPGSVDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDY 82
Query: 522 CGNGAA--CYTAQSDYYCHCAPGW----TGKNC 548
G C +Y C C G+ G NC
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 100 bits (239), Expect = 3e-20
Identities = 98/378 (25%), Positives = 147/378 (38%), Gaps = 52/378 (13%)
Query: 198 CLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQC--QPYPGCKHGYCN 255
C ++ + C P+ G H C C W E C +C + P +
Sbjct: 162 CFLRYEDEECTLPIA--GRHRMDACC-----CSVGAAWGTEECEECPMRNTPEYEELCPR 214
Query: 256 GSSWDCTCDTNWGGILCDQDLNYCGTHEP-CQHGGTCENTAPDQYFCRCAEGFS----GV 310
G + TN G +D+N C C HG C NT + CRC GF+
Sbjct: 215 GPGFATKEITN--GKPFFKDINECKMIPSLCTHG-KCRNTI-GSFKCRCDSGFALDSEER 270
Query: 311 DCERVDN-PCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXXXXAS----GPCL- 364
+C +D +P C G C T F C CD G+ P L
Sbjct: 271 NCTDIDECRISPDLCGRGQC--VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 328
Query: 365 HGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSC 424
G C + + CEC G + ++ C + E + C N C N G Y C
Sbjct: 329 RGGVCHNTEGSYRCECPPGHQ---LSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC 384
Query: 425 ACLAGWTGRDCE---TNVDDCT---GQCLHGATCIDLVDDFHCACAAGYA----GRTCSL 474
AC G+ ++D+C+ G C C + + C+C G+A R+C+
Sbjct: 385 ACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCT- 441
Query: 475 DVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGT----NCEDDRDHCAGSP--CGNGAA 527
D+D+C P +GG+C ++ YRC+C GF + C D + C +P C +G
Sbjct: 442 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE-CDLNPNICLSG-T 499
Query: 528 CYTAQSDYYCHCAPGWTG 545
C + + CHC G++G
Sbjct: 500 CENTKGSFICHCDMGYSG 517
Score = 77.0 bits (181), Expect = 3e-13
Identities = 111/473 (23%), Positives = 164/473 (34%), Gaps = 73/473 (15%)
Query: 237 GELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAP 296
G C+ CQ P C GY C +D++ C G C NT
Sbjct: 88 GSPCTLCQVDPICGKGYSRIKGTQC------------EDIDECEVFPGVCKNGLCVNTR- 134
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPC------AHGTCSLAGTTRGFTCTCDRGWGGXX 350
+ C+C G + R+ + C T +AG R C C G
Sbjct: 135 GSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGT 194
Query: 351 XXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCV 410
+ P R GF + + G +D++EC +
Sbjct: 195 EECEECPMRNTPEYEELCPRG--PGFATK--EITNGKPFFKDINECK-------MIPSLC 243
Query: 411 NAAACNNTAGGYSCACLAGWT----GRDCETNVDDCT---GQCLHGATCIDLVDDFHCAC 463
C NT G + C C +G+ R+C T++D+C C G C++ DF C C
Sbjct: 244 THGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRGQ-CVNTPGDFECKC 301
Query: 464 AAGYAG-----RTCSLDVDDCAPRPCT-NGGECVDLLNAYRCICPVGFS---GTNCEDDR 514
GY + C +D+D+C P GG C + +YRC CP G + D
Sbjct: 302 DEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 360
Query: 515 DHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEG 572
+ C S C NG C Y C C PG+ + DR C V ++E G
Sbjct: 361 NECELSAHLCPNGR-CVNLIGKYQCACNPGY-------HSTPDRLFC-VDIDECS-IMNG 410
Query: 573 MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXXXXQAGGTCLPSALPPGWA 632
C C EGS+ GG C + +P +
Sbjct: 411 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 466
Query: 633 CGCREGRTGA----LCELSLDLCGSSP--CRNGGRCVGGSGWWMCECVAGWTG 679
C C +G + C + ++ C +P C +G C G ++C C G++G
Sbjct: 467 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSG 517
Score = 33.1 bits (72), Expect = 5.1
Identities = 40/155 (25%), Positives = 53/155 (34%), Gaps = 33/155 (21%)
Query: 165 CQPNYYNTTCTTFCRPRDD-KFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTHG 221
C P Y++T FC D+ + C + C C C+ G P
Sbjct: 386 CNPGYHSTPDRLFCVDIDECSIMNGGC----ETFCTNSEGSYECS---CQPGFALMPDQR 438
Query: 222 RCDRPGDCDCRPGWRGELC--SQCQPYPG-----CKHGYCNGSSWDCTCDTNWGGILCDQ 274
C +C+ P +C QC PG C G+ D N CD
Sbjct: 439 SCTDIDECEDNP----NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDL 490
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSG 309
+ N C GTCENT + C C G+SG
Sbjct: 491 NPNIC-------LSGTCENT-KGSFICHCDMGYSG 517
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 97.9 bits (233), Expect = 2e-19
Identities = 107/392 (27%), Positives = 158/392 (40%), Gaps = 70/392 (17%)
Query: 243 CQPYPGCKHGYCN--GSSWDCTCDTNWG----GILCDQDLNYCGTH-EPCQHGGTCENTA 295
C+ CK C+ G S C+C + G+ C+ D+N C T C G C NT
Sbjct: 683 CKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCE-DINECVTDLHTCSRGEHCVNTL 740
Query: 296 PDQYFC----RCAEGFSGVD--CERVDNPCA--PQPCAHGTCSLAGTTRG-FTCT----C 342
+ C C G++ D CE VD CA C G L T+G F C C
Sbjct: 741 -GSFHCYKALTCEPGYALKDGECEDVDE-CAMGTHTCQPGF--LCQNTKGSFYCQARQRC 796
Query: 343 DRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE-----CADGWTGPACAEDV 393
G+ G S PC G SC + + +TC+ CA G+ ++D
Sbjct: 797 MDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA---SDDG 853
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQ---- 445
+C + E + C C+N G Y C C AG+ GR C +V++C
Sbjct: 854 AKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNECWASPGRL 912
Query: 446 CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C H TC + + + C+CA+G+ G+ C DV++C + C+ EC ++ +Y+C C
Sbjct: 913 CQH--TCENTLGSYRCSCASGFLLAADGKRCE-DVNECEAQRCSQ--ECANIYGSYQCYC 967
Query: 502 PVGF----SGTNCEDDRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
G+ G C D D CA G+ C Y C C R+ +D
Sbjct: 968 RQGYQLAEDGHTC-TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1026
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
C++ C+ TC +GS+R
Sbjct: 1027 DECALGTHN--------CSEAETCHNIQGSFR 1050
Score = 54.8 bits (126), Expect = 1e-06
Identities = 81/297 (27%), Positives = 117/297 (39%), Gaps = 57/297 (19%)
Query: 165 CQPNYY--NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTH 220
CQP + NT + +C+ R + P+G+ C+ + + +P C+ G C T
Sbjct: 775 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINECTSLSEP-CRPGFSCINTV 831
Query: 221 GR--CDRPGDCDCRPGWR----GELC---SQCQP-YPGCKHGY-CNG--SSWDCTCDTNW 267
G C R C G+ G C ++C+ C G C+ S+ C C +
Sbjct: 832 GSYTCQR-NPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
Query: 268 GGILCDQ---DLNYCGTHEP--CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNP 318
+ D+N C CQH TCENT Y C CA GF G CE V N
Sbjct: 891 QRDAFGRGCIDVNECWASPGRLCQH--TCENTL-GSYRCSCASGFLLAADGKRCEDV-NE 946
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLD 374
C Q C+ ++ G+ + C C +G+ G L C +
Sbjct: 947 CEAQRCSQECANIYGS---YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPG 1003
Query: 375 GFTCECAD-GWT----GPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSC 424
+ C C + G+T G +C +DVDEC ALG C A C+N G + C
Sbjct: 1004 SYQCACPEQGYTMTANGRSC-KDVDEC--------ALGTHNCSEAETCHNIQGSFRC 1051
Score = 33.1 bits (72), Expect = 5.1
Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 21/126 (16%)
Query: 446 CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C H CI+ V +HCAC G++ GRTC + P +
Sbjct: 616 CQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 502 PVGFSGTN-CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT----GKNC--TQRAAR 554
P+ N C+D+ PC C T C C PG+ G +C
Sbjct: 674 PLPLPQPNTCKDN------GPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECVT 725
Query: 555 DRKTCS 560
D TCS
Sbjct: 726 DLHTCS 731
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 97.9 bits (233), Expect = 2e-19
Identities = 107/392 (27%), Positives = 158/392 (40%), Gaps = 70/392 (17%)
Query: 243 CQPYPGCKHGYCN--GSSWDCTCDTNWG----GILCDQDLNYCGTH-EPCQHGGTCENTA 295
C+ CK C+ G S C+C + G+ C+ D+N C T C G C NT
Sbjct: 683 CKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCE-DINECVTDLHTCSRGEHCVNTL 740
Query: 296 PDQYFC----RCAEGFSGVD--CERVDNPCA--PQPCAHGTCSLAGTTRG-FTCT----C 342
+ C C G++ D CE VD CA C G L T+G F C C
Sbjct: 741 -GSFHCYKALTCEPGYALKDGECEDVDE-CAMGTHTCQPGF--LCQNTKGSFYCQARQRC 796
Query: 343 DRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGFTCE-----CADGWTGPACAEDV 393
G+ G S PC G SC + + +TC+ CA G+ ++D
Sbjct: 797 MDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA---SDDG 853
Query: 394 DECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT----GRDCETNVDDCTGQ---- 445
+C + E + C C+N G Y C C AG+ GR C +V++C
Sbjct: 854 AKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNECWASPGRL 912
Query: 446 CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C H TC + + + C+CA+G+ G+ C DV++C + C+ EC ++ +Y+C C
Sbjct: 913 CQH--TCENTLGSYRCSCASGFLLAADGKRCE-DVNECEAQRCSQ--ECANIYGSYQCYC 967
Query: 502 PVGF----SGTNCEDDRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
G+ G C D D CA G+ C Y C C R+ +D
Sbjct: 968 RQGYQLAEDGHTC-TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1026
Query: 557 KTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
C++ C+ TC +GS+R
Sbjct: 1027 DECALGTHN--------CSEAETCHNIQGSFR 1050
Score = 55.2 bits (127), Expect = 1e-06
Identities = 87/330 (26%), Positives = 127/330 (38%), Gaps = 63/330 (19%)
Query: 165 CQPNYY--NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTH 220
CQP + NT + +C+ R + P+G+ C+ + + +P C+ G C T
Sbjct: 775 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINECTSLSEP-CRPGFSCINTV 831
Query: 221 GR--CDRPGDCDCRPGWR----GELC---SQCQP-YPGCKHGY-CNG--SSWDCTCDTNW 267
G C R C G+ G C ++C+ C G C+ S+ C C +
Sbjct: 832 GSYTCQR-NPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
Query: 268 GGILCDQ---DLNYCGTHEP--CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNP 318
+ D+N C CQH TCENT Y C CA GF G CE V N
Sbjct: 891 QRDAFGRGCIDVNECWASPGRLCQH--TCENTL-GSYRCSCASGFLLAADGKRCEDV-NE 946
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLD 374
C Q C+ ++ G+ + C C +G+ G L C +
Sbjct: 947 CEAQRCSQECANIYGS---YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPG 1003
Query: 375 GFTCECAD-GWT----GPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSCACL 427
+ C C + G+T G +C +DVDEC ALG C A C+N G + C L
Sbjct: 1004 SYQCACPEQGYTMTANGRSC-KDVDEC--------ALGTHNCSEAETCHNIQGSFRCLRL 1054
Query: 428 AGWTGRDCETNVDDCTGQCLHGATCIDLVD 457
+C N + TC D ++
Sbjct: 1055 ------ECPPNYVQVSKTKCERTTCHDFLE 1078
Score = 33.1 bits (72), Expect = 5.1
Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 21/126 (16%)
Query: 446 CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDCAPRPCTNGGECVDLLNAYRCIC 501
C H CI+ V +HCAC G++ GRTC + P +
Sbjct: 616 CQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 502 PVGFSGTN-CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWT----GKNC--TQRAAR 554
P+ N C+D+ PC C T C C PG+ G +C
Sbjct: 674 PLPLPQPNTCKDN------GPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECVT 725
Query: 555 DRKTCS 560
D TCS
Sbjct: 726 DLHTCS 731
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 97.9 bits (233), Expect = 2e-19
Identities = 79/294 (26%), Positives = 110/294 (37%), Gaps = 42/294 (14%)
Query: 275 DLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFS----GVDCERVDNPCAPQPCAHGTCS 330
D + C PC H +C N A Y+C C +G + G C+ +D + H
Sbjct: 330 DEDECAAGNPCSH--SCHN-AMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQD 386
Query: 331 LAGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDH----LDGFTCECADGWT- 385
T + C G G C + C + F C C G+
Sbjct: 387 CDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQL 446
Query: 386 -GPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCA--CLAGWTGRDCET--NVD 440
G C DV+EC C C NT GGY C C G T + T ++D
Sbjct: 447 KGRKCM-DVNECRQNV--------CRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDID 497
Query: 441 DC---TGQCLHGATCIDLVDDFHCACAAGY----AGRTCSLDVDDCAPRPCTNGGECVDL 493
+C T QC + C + + C C GY GR C +D+D+C EC +
Sbjct: 498 ECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPC-MDIDECENTDACQH-ECKNT 555
Query: 494 LNAYRCICPVGF----SGTNCEDDRDHC--AGSPCGNGAACYTAQSDYYCHCAP 541
+Y+CICP G+ +G C+ D D C CG C+ + Y C P
Sbjct: 556 FGSYQCICPPGYQLTHNGKTCQ-DIDECLEQNVHCGPNRMCFNMRGSYQCIDTP 608
Score = 67.3 bits (157), Expect = 3e-10
Identities = 56/192 (29%), Positives = 84/192 (43%), Gaps = 36/192 (18%)
Query: 420 GGYSCACLAGWT----GRDCETNVDDCTG--QCLHGATCIDLVDDFHCACAAGYA----G 469
G S C +G+T G C + D+C C H +C + + ++C+C G G
Sbjct: 309 GDRSNQCPSGFTLDSVGPFC-ADEDECAAGNPCSH--SCHNAMGTYYCSCPKGLTIAADG 365
Query: 470 RTCSLDVDDCA--PRPCTNGGECVDLLNAYRCI--CPVGF----SGTNCEDDRDHCAGSP 521
RTC D+D+CA C G +C + + +YRC+ C GF G +C+D + SP
Sbjct: 366 RTCQ-DIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 424
Query: 522 CGNGAACYTAQSDYYCHCAPGWTGK--------NCTQRAARDRKTCSVL---VEESERCA 570
C C+ A ++C C PG+ K C Q R + C + + C
Sbjct: 425 CHQ--RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCP 482
Query: 571 EGMC-ANGGTCV 581
GM A GTC+
Sbjct: 483 NGMTKAENGTCI 494
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/179 (25%), Positives = 64/179 (35%), Gaps = 24/179 (13%)
Query: 501 CPVGFS----GTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDR 556
CP GF+ G C D+ + AG+PC + +C+ A YYC C G T A D
Sbjct: 315 CPSGFTLDSVGPFCADEDECAAGNPCSH--SCHNAMGTYYCSCPKGLT-------IAADG 365
Query: 557 KTCSVLVEESERCAEG--MCANGGTCVREEGSWRXXXXXXXXXXXXDSXXXXXXXXXXXX 614
+TC ++ + CA G C G C GS+R
Sbjct: 366 RTC----QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE 421
Query: 615 XXQAGGTCLPSALPPGWACGCREG--RTGALCELSLDLCGSSPCRNGGRCVGGSGWWMC 671
C + + CGC G G C + ++ C + CR C G + C
Sbjct: 422 SSPCHQRCFNAI--GSFHCGCEPGYQLKGRKC-MDVNECRQNVCRPDQHCKNTRGGYKC 477
>AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein.
Length = 866
Score = 96.7 bits (230), Expect = 4e-19
Identities = 102/360 (28%), Positives = 130/360 (36%), Gaps = 75/360 (20%)
Query: 190 CTPDGDKHCLPGWQGDNCEK--------PVCKE--GCHPTHGRC-DRPGDCDCRPGWRGE 238
C G+ C G+ G NC+ P CKE CHP HG+C D G C C G
Sbjct: 92 CVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP-HGQCEDVTGQCTCHARRWGA 150
Query: 239 LCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGI------------LCDQDLNYCGTH--- 282
C CQ C+HG C+ S C C++ W G CD C H
Sbjct: 151 RCEHACQ----CQHGTCHPRSGACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGW 206
Query: 283 --EPCQHGGTCENTAPDQYF--CRCAEGFSGVDCERVDNPCAPQPC--AHGTCSLAGTTR 336
C + C ++ +Q C+C E G C+R C C GTC+ R
Sbjct: 207 WGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQ-CFRGRCHPVDGTCACEPGYR 265
Query: 337 GFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C C G+ G G C C +G C GW G C +
Sbjct: 266 GKYCREPCPAGFYG-----LGCRRRCGQCKGQQPC-TVAEGRCLTCEPGWNGTKCDQ--- 316
Query: 395 ECSGRSMTEGA---LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGAT 451
C+ EG PC + ACN+ G + C AGW G CET + T +G
Sbjct: 317 PCATGFYGEGCSHRCPPCRDGHACNHVTGKCT-RCNAGWIGDRCETKCSNGT----YGED 371
Query: 452 CIDLVDDFHCA-CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
C F CA C +G+ C C P +G C CP G G +C
Sbjct: 372 CA-----FVCADCGSGH----CDFQSGRCLCSPGVHGPHC-------NVTCPPGLHGADC 415
Score = 75.4 bits (177), Expect = 1e-12
Identities = 96/342 (28%), Positives = 111/342 (32%), Gaps = 66/342 (19%)
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
TC W + + C + C C P + CRC G+ G +C D C
Sbjct: 63 TCCAGWRQQGDECGIAVCEGNSTCSENEVC--VRPGE--CRCRHGYFGANC---DTKCPR 115
Query: 322 Q---PCAHGTCSLA--GTTRGFT--CTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
Q P CS G T CTC R WG C HG +C H
Sbjct: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------CQHG-TC--HP 165
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
C C GW G CA CS S + G C+ A + CAC
Sbjct: 166 RSGACRCESGWWGAQCASAC-YCSATSRCDPQTGACLCHAGWWGRSCNNQCAC----NSS 220
Query: 434 DCETNVDDCTGQCLH---GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
CE C QC GA C D +C C + GR +D CA P G C
Sbjct: 221 PCEQQSGRC--QCRERTFGARC-----DRYCQC---FRGRCHPVD-GTCACEPGYRGKYC 269
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
R CP GF G C C G PC T C PGW G C
Sbjct: 270 -------REPCPAGFYGLGCRRRCGQCKGQQPC-------TVAEGRCLTCEPGWNGTKCD 315
Query: 550 QRAARD--RKTCSVLVEESERCAEGMCAN--GGTCVREEGSW 587
Q A + CS C +G N G C R W
Sbjct: 316 QPCATGFYGEGCS---HRCPPCRDGHACNHVTGKCTRCNAGW 354
Score = 33.9 bits (74), Expect = 2.9
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 2/44 (4%)
Query: 633 CGCREGRTGALCELSLDLCGSSPCR-NGGRCVGGSGWWMCECVA 675
C C R GA CE + C C G C SGWW +C +
Sbjct: 141 CTCHARRWGARCEHACQ-CQHGTCHPRSGACRCESGWWGAQCAS 183
Score = 32.3 bits (70), Expect = 8.8
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 12/63 (19%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTG 679
GTC P + AC C G GA C + C RC +G C C AGW G
Sbjct: 161 GTCHPRS----GACRCESGWWGAQC------ASACYCSATSRCDPQTG--ACLCHAGWWG 208
Query: 680 ETC 682
+C
Sbjct: 209 RSC 211
>BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 96.3 bits (229), Expect = 5e-19
Identities = 69/232 (29%), Positives = 95/232 (40%), Gaps = 25/232 (10%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA--GSPCGNG 525
G C GG CV +C+CP GF+G++CE D D CA C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECALRTHTCWND 563
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
+AC + C C G + + V + +RC+ C +G
Sbjct: 564 SACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDG 615
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/142 (28%), Positives = 55/142 (38%), Gaps = 18/142 (12%)
Query: 216 CHPTHGRCDRPG--DCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
CH + PG CDC PG+ C + C G N + C G C
Sbjct: 445 CHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE-NAICTNTVQGHSCT 503
Query: 274 QDLNYCGT--------HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQP 323
Y G E C++GGTC AP++ C C GF+G CE+ + CA
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTC--VAPNK--CVCPSGFTGSHCEKDIDECALRTHT 559
Query: 324 CAHGTCSLAGTTRGFTCTCDRG 345
C + + + GF C C G
Sbjct: 560 CWNDSACI-NLAGGFDCLCPSG 580
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 7/60 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C + C N C+ +G + C C +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
>BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 96.3 bits (229), Expect = 5e-19
Identities = 69/232 (29%), Positives = 95/232 (40%), Gaps = 25/232 (10%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCA--GSPCGNG 525
G C GG CV +C+CP GF+G++CE D D CA C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECALRTHTCWND 563
Query: 526 AACYTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANG 577
+AC + C C G + + V + +RC+ C +G
Sbjct: 564 SACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDG 615
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/142 (28%), Positives = 55/142 (38%), Gaps = 18/142 (12%)
Query: 216 CHPTHGRCDRPG--DCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCD 273
CH + PG CDC PG+ C + C G N + C G C
Sbjct: 445 CHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE-NAICTNTVQGHSCT 503
Query: 274 QDLNYCGT--------HEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCA--PQP 323
Y G E C++GGTC AP++ C C GF+G CE+ + CA
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTC--VAPNK--CVCPSGFTGSHCEKDIDECALRTHT 559
Query: 324 CAHGTCSLAGTTRGFTCTCDRG 345
C + + + GF C C G
Sbjct: 560 CWNDSACI-NLAGGFDCLCPSG 580
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 7/60 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLCG--SSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C + C N C+ +G + C C +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
>AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type F
protein.
Length = 870
Score = 95.9 bits (228), Expect = 6e-19
Identities = 102/360 (28%), Positives = 129/360 (35%), Gaps = 75/360 (20%)
Query: 190 CTPDGDKHCLPGWQGDNCEK--------PVCKE--GCHPTHGRC-DRPGDCDCRPGWRGE 238
C G+ C G+ G NC+ P CKE CHP HG+C D G C C G
Sbjct: 92 CVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP-HGQCEDVTGQCTCHARRWGA 150
Query: 239 LCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGI------------LCDQDLNYCGTH--- 282
C CQ C+HG C+ S C C+ W G CD C H
Sbjct: 151 RCEHACQ----CQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGW 206
Query: 283 --EPCQHGGTCENTAPDQYF--CRCAEGFSGVDCERVDNPCAPQPC--AHGTCSLAGTTR 336
C + C ++ +Q C+C E G C+R C C GTC+ R
Sbjct: 207 WGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQ-CFRGRCHPVDGTCACEPGYR 265
Query: 337 GFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C C G+ G G C C +G C GW G C +
Sbjct: 266 GKYCREPCPAGFYG-----LGCRRRCGQCKGQQPC-TVAEGRCLTCEPGWNGTKCDQ--- 316
Query: 395 ECSGRSMTEGA---LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGAT 451
C+ EG PC + ACN+ G + C AGW G CET + T +G
Sbjct: 317 PCATGFYGEGCSHRCPPCRDGHACNHVTGKCT-RCNAGWIGDRCETKCSNGT----YGED 371
Query: 452 CIDLVDDFHCA-CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
C F CA C +G+ C C P +G C CP G G +C
Sbjct: 372 CA-----FVCADCGSGH----CDFQSGRCLCSPGVHGPHC-------NVTCPPGLHGADC 415
Score = 74.9 bits (176), Expect = 1e-12
Identities = 96/342 (28%), Positives = 111/342 (32%), Gaps = 66/342 (19%)
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
TC W + + C + C C P + CRC G+ G +C D C
Sbjct: 63 TCCAGWRQQGDECGIAVCEGNSTCSENEVC--VRPGE--CRCRHGYFGANC---DTKCPR 115
Query: 322 Q---PCAHGTCSLA--GTTRGFT--CTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
Q P CS G T CTC R WG C HG +C H
Sbjct: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------CQHG-TC--HP 165
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
C C GW G CA CS S + G C+ A + CAC
Sbjct: 166 RSGACRCEPGWWGAQCASAC-YCSATSRCDPQTGACLCHAGWWGRSCNNQCAC----NSS 220
Query: 434 DCETNVDDCTGQCLH---GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
CE C QC GA C D +C C + GR +D CA P G C
Sbjct: 221 PCEQQSGRC--QCRERTFGARC-----DRYCQC---FRGRCHPVD-GTCACEPGYRGKYC 269
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
R CP GF G C C G PC T C PGW G C
Sbjct: 270 -------REPCPAGFYGLGCRRRCGQCKGQQPC-------TVAEGRCLTCEPGWNGTKCD 315
Query: 550 QRAARD--RKTCSVLVEESERCAEGMCAN--GGTCVREEGSW 587
Q A + CS C +G N G C R W
Sbjct: 316 QPCATGFYGEGCS---HRCPPCRDGHACNHVTGKCTRCNAGW 354
Score = 33.5 bits (73), Expect = 3.8
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWWMCEC 673
GTC P + AC C G GA C + +S C G C+ +GWW C
Sbjct: 161 GTCHPRS----GACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSC 211
>AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein.
Length = 866
Score = 95.9 bits (228), Expect = 6e-19
Identities = 102/360 (28%), Positives = 129/360 (35%), Gaps = 75/360 (20%)
Query: 190 CTPDGDKHCLPGWQGDNCEK--------PVCKE--GCHPTHGRC-DRPGDCDCRPGWRGE 238
C G+ C G+ G NC+ P CKE CHP HG+C D G C C G
Sbjct: 92 CVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP-HGQCEDVTGQCTCHARRWGA 150
Query: 239 LCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGI------------LCDQDLNYCGTH--- 282
C CQ C+HG C+ S C C+ W G CD C H
Sbjct: 151 RCEHACQ----CQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGW 206
Query: 283 --EPCQHGGTCENTAPDQYF--CRCAEGFSGVDCERVDNPCAPQPC--AHGTCSLAGTTR 336
C + C ++ +Q C+C E G C+R C C GTC+ R
Sbjct: 207 WGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQ-CFRGRCHPVDGTCACEPGYR 265
Query: 337 GFTC--TCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
G C C G+ G G C C +G C GW G C +
Sbjct: 266 GKYCREPCPAGFYG-----LGCRRRCGQCKGQQPC-TVAEGRCLTCEPGWNGTKCDQ--- 316
Query: 395 ECSGRSMTEGA---LGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGAT 451
C+ EG PC + ACN+ G + C AGW G CET + T +G
Sbjct: 317 PCATGFYGEGCSHRCPPCRDGHACNHVTGKCT-RCNAGWIGDRCETKCSNGT----YGED 371
Query: 452 CIDLVDDFHCA-CAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNC 510
C F CA C +G+ C C P +G C CP G G +C
Sbjct: 372 CA-----FVCADCGSGH----CDFQSGRCLCSPGVHGPHC-------NVTCPPGLHGADC 415
Score = 74.9 bits (176), Expect = 1e-12
Identities = 96/342 (28%), Positives = 111/342 (32%), Gaps = 66/342 (19%)
Query: 262 TCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAP 321
TC W + + C + C C P + CRC G+ G +C D C
Sbjct: 63 TCCAGWRQQGDECGIAVCEGNSTCSENEVC--VRPGE--CRCRHGYFGANC---DTKCPR 115
Query: 322 Q---PCAHGTCSLA--GTTRGFT--CTCD-RGWGGXXXXXXXXXXASGPCLHGASCRDHL 373
Q P CS G T CTC R WG C HG +C H
Sbjct: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------CQHG-TC--HP 165
Query: 374 DGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGR 433
C C GW G CA CS S + G C+ A + CAC
Sbjct: 166 RSGACRCEPGWWGAQCASAC-YCSATSRCDPQTGACLCHAGWWGRSCNNQCAC----NSS 220
Query: 434 DCETNVDDCTGQCLH---GATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGEC 490
CE C QC GA C D +C C + GR +D CA P G C
Sbjct: 221 PCEQQSGRC--QCRERTFGARC-----DRYCQC---FRGRCHPVD-GTCACEPGYRGKYC 269
Query: 491 VDLLNAYRCICPVGFSGTNCEDDRDHCAGS-PCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
R CP GF G C C G PC T C PGW G C
Sbjct: 270 -------REPCPAGFYGLGCRRRCGQCKGQQPC-------TVAEGRCLTCEPGWNGTKCD 315
Query: 550 QRAARD--RKTCSVLVEESERCAEGMCAN--GGTCVREEGSW 587
Q A + CS C +G N G C R W
Sbjct: 316 QPCATGFYGEGCS---HRCPPCRDGHACNHVTGKCTRCNAGW 354
Score = 33.5 bits (73), Expect = 3.8
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 620 GTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWWMCEC 673
GTC P + AC C G GA C + +S C G C+ +GWW C
Sbjct: 161 GTCHPRS----GACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSC 211
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 95.1 bits (226), Expect = 1e-18
Identities = 78/277 (28%), Positives = 109/277 (39%), Gaps = 57/277 (20%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----------SGVDCERVDNPC-APQPC 324
N C C TC NT D Y+C C +GF GV C+ +D +PQPC
Sbjct: 33 NNCRDSTLCPAYATCTNTV-DSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
Query: 325 A-HGTC-SLAGTTR-----GFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDH 372
+ +C +L+G + GF+ W G S C + C +
Sbjct: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
Query: 373 LDGFTCECADGWTGP-ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ ++C C G+ + EDVDEC+ C A CNNT G YSC C G+
Sbjct: 152 MGSYSCSCQVGFISRNSTCEDVDECADPRA-------CPEHATCNNTVGNYSCFCNPGFE 204
Query: 432 G-----------RDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL------ 474
CE ++D+CT C +TC + + C C G+A L
Sbjct: 205 SSSGHLSFQGLKASCE-DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQG 263
Query: 475 ----DVDDCAPRPCTNGGE--CVDLLNAYRCICPVGF 505
D+D+C P T G C + L +Y C C GF
Sbjct: 264 VECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 87.8 bits (208), Expect = 2e-16
Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 49/224 (21%)
Query: 363 CLHGASCRDHLDGFTCECADGWT-----------GPACAEDVDECSGRSMTEGALGPCVN 411
C A+C + +D + C C G+ G C +D+DECS PC
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC-KDIDECSQSPQ------PCGP 93
Query: 412 AAACNNTAGGYSCACLAGW---TGRDCE---------TNVDDC--TGQCLHGATCIDLVD 457
++C N +G Y C+CL G+ TG D T++++C + C + C++ +
Sbjct: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMG 153
Query: 458 DFHCACAAGYAGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGFSGTN----- 509
+ C+C G+ R TC DVD+CA PR C C + + Y C C GF ++
Sbjct: 154 SYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 212
Query: 510 ------CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
CED D C C + C Y+C C PG+ N
Sbjct: 213 QGLKASCEDI-DECT-EMCPINSTCTNTPGSYFCTCHPGFAPSN 254
Score = 80.6 bits (190), Expect = 3e-14
Identities = 60/215 (27%), Positives = 92/215 (42%), Gaps = 37/215 (17%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR-SMTEGALGPCVNAAACN---- 416
PC +SC++ + C C DG++ P + V G S T+ + C+ ++ C
Sbjct: 90 PCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTD--INECLTSSVCPEHSD 147
Query: 417 --NTAGGYSCACLAGWTGRD--CETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGR 470
N+ G YSC+C G+ R+ CE +VD+C C ATC + V ++ C C G+
Sbjct: 148 CVNSMGSYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
Query: 471 TCSL----------DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE--------- 511
+ L D+D+C C C + +Y C C GF+ +N +
Sbjct: 207 SGHLSFQGLKASCEDIDECTEM-CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 512 -DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGW 543
D D C P CG + C A Y C C G+
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 75.4 bits (177), Expect = 1e-12
Identities = 60/239 (25%), Positives = 91/239 (38%), Gaps = 37/239 (15%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C W G G + + L P A C NT Y CAC G+ + +
Sbjct: 12 CCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAY--ATCTNTVDSYYCACKQGFLSSNGQN 69
Query: 438 N----------VDDCTGQ---CLHGATCIDLVDDFHCACAAGYA------------GRTC 472
+ +D+C+ C ++C +L + C+C G++ G
Sbjct: 70 HFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFS 129
Query: 473 SLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGS-PCGNGAAC 528
D+++C C +CV+ + +Y C C VGF N CED D CA C A C
Sbjct: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDV-DECADPRACPEHATC 188
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+Y C C PG+ + + +C E+ + C E MC TC GS+
Sbjct: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASC----EDIDECTE-MCPINSTCTNTPGSY 242
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/161 (26%), Positives = 63/161 (39%), Gaps = 34/161 (21%)
Query: 422 YSCACLAGWTG-----RDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA------ 468
+ C + W G R T ++C C ATC + VD ++CAC G+
Sbjct: 10 WGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQN 69
Query: 469 -----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT------------- 508
G C D+D+C+ P+PC C +L Y+C C GFS
Sbjct: 70 HFKDPGVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNF 128
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+C D + S C + C + Y C C G+ +N T
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST 169
Score = 41.9 bits (94), Expect = 0.011
Identities = 53/219 (24%), Positives = 72/219 (32%), Gaps = 55/219 (25%)
Query: 225 RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNW--GGILCDQDLNYCGTH 282
+PG+ C S C + C + S+ C+C + C+ D++ C
Sbjct: 124 KPGNFSCTDINECLTSSVCPEHSDCVNSM---GSYSCSCQVGFISRNSTCE-DVDECADP 179
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGF---SG--------VDCERVDNPCAPQPCAHGTCSL 331
C TC NT Y C C GF SG CE +D C + TC+
Sbjct: 180 RACPEHATCNNTV-GNYSCFCNPGFESSSGHLSFQGLKASCEDIDE-CTEMCPINSTCT- 236
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE 391
T + CTC G+ G CRD
Sbjct: 237 -NTPGSYFCTCHPGFAPSNGQLNFTD-------QGVECRD-------------------- 268
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DEC T C + C N G YSC C+AG+
Sbjct: 269 -IDECRQDPST------CGPNSICTNALGSYSCGCIAGF 300
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 95.1 bits (226), Expect = 1e-18
Identities = 78/277 (28%), Positives = 109/277 (39%), Gaps = 57/277 (20%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----------SGVDCERVDNPC-APQPC 324
N C C TC NT D Y+C C +GF GV C+ +D +PQPC
Sbjct: 33 NNCRDSTLCPAYATCTNTV-DSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
Query: 325 A-HGTC-SLAGTTR-----GFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDH 372
+ +C +L+G + GF+ W G S C + C +
Sbjct: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
Query: 373 LDGFTCECADGWTGP-ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ ++C C G+ + EDVDEC+ C A CNNT G YSC C G+
Sbjct: 152 MGSYSCSCQVGFISRNSTCEDVDECADPRA-------CPEHATCNNTVGNYSCFCNPGFE 204
Query: 432 G-----------RDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL------ 474
CE ++D+CT C +TC + + C C G+A L
Sbjct: 205 SSSGHLSFQGLKASCE-DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQG 263
Query: 475 ----DVDDCAPRPCTNGGE--CVDLLNAYRCICPVGF 505
D+D+C P T G C + L +Y C C GF
Sbjct: 264 VECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 87.8 bits (208), Expect = 2e-16
Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 49/224 (21%)
Query: 363 CLHGASCRDHLDGFTCECADGWT-----------GPACAEDVDECSGRSMTEGALGPCVN 411
C A+C + +D + C C G+ G C +D+DECS PC
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC-KDIDECSQSPQ------PCGP 93
Query: 412 AAACNNTAGGYSCACLAGW---TGRDCE---------TNVDDC--TGQCLHGATCIDLVD 457
++C N +G Y C+CL G+ TG D T++++C + C + C++ +
Sbjct: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMG 153
Query: 458 DFHCACAAGYAGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGFSGTN----- 509
+ C+C G+ R TC DVD+CA PR C C + + Y C C GF ++
Sbjct: 154 SYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 212
Query: 510 ------CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
CED D C C + C Y+C C PG+ N
Sbjct: 213 QGLKASCEDI-DECT-EMCPINSTCTNTPGSYFCTCHPGFAPSN 254
Score = 80.6 bits (190), Expect = 3e-14
Identities = 60/215 (27%), Positives = 92/215 (42%), Gaps = 37/215 (17%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR-SMTEGALGPCVNAAACN---- 416
PC +SC++ + C C DG++ P + V G S T+ + C+ ++ C
Sbjct: 90 PCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTD--INECLTSSVCPEHSD 147
Query: 417 --NTAGGYSCACLAGWTGRD--CETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGR 470
N+ G YSC+C G+ R+ CE +VD+C C ATC + V ++ C C G+
Sbjct: 148 CVNSMGSYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
Query: 471 TCSL----------DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE--------- 511
+ L D+D+C C C + +Y C C GF+ +N +
Sbjct: 207 SGHLSFQGLKASCEDIDECTEM-CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 512 -DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGW 543
D D C P CG + C A Y C C G+
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Score = 75.4 bits (177), Expect = 1e-12
Identities = 60/239 (25%), Positives = 91/239 (38%), Gaps = 37/239 (15%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C W G G + + L P A C NT Y CAC G+ + +
Sbjct: 12 CCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAY--ATCTNTVDSYYCACKQGFLSSNGQN 69
Query: 438 N----------VDDCTGQ---CLHGATCIDLVDDFHCACAAGYA------------GRTC 472
+ +D+C+ C ++C +L + C+C G++ G
Sbjct: 70 HFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFS 129
Query: 473 SLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGS-PCGNGAAC 528
D+++C C +CV+ + +Y C C VGF N CED D CA C A C
Sbjct: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDV-DECADPRACPEHATC 188
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+Y C C PG+ + + +C E+ + C E MC TC GS+
Sbjct: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASC----EDIDECTE-MCPINSTCTNTPGSY 242
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/161 (26%), Positives = 63/161 (39%), Gaps = 34/161 (21%)
Query: 422 YSCACLAGWTG-----RDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA------ 468
+ C + W G R T ++C C ATC + VD ++CAC G+
Sbjct: 10 WGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQN 69
Query: 469 -----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT------------- 508
G C D+D+C+ P+PC C +L Y+C C GFS
Sbjct: 70 HFKDPGVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNF 128
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+C D + S C + C + Y C C G+ +N T
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST 169
Score = 41.9 bits (94), Expect = 0.011
Identities = 53/219 (24%), Positives = 72/219 (32%), Gaps = 55/219 (25%)
Query: 225 RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNW--GGILCDQDLNYCGTH 282
+PG+ C S C + C + S+ C+C + C+ D++ C
Sbjct: 124 KPGNFSCTDINECLTSSVCPEHSDCVNSM---GSYSCSCQVGFISRNSTCE-DVDECADP 179
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGF---SG--------VDCERVDNPCAPQPCAHGTCSL 331
C TC NT Y C C GF SG CE +D C + TC+
Sbjct: 180 RACPEHATCNNTV-GNYSCFCNPGFESSSGHLSFQGLKASCEDIDE-CTEMCPINSTCT- 236
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE 391
T + CTC G+ G CRD
Sbjct: 237 -NTPGSYFCTCHPGFAPSNGQLNFTD-------QGVECRD-------------------- 268
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DEC T C + C N G YSC C+AG+
Sbjct: 269 -IDECRQDPST------CGPNSICTNALGSYSCGCIAGF 300
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 95.1 bits (226), Expect = 1e-18
Identities = 78/277 (28%), Positives = 109/277 (39%), Gaps = 57/277 (20%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----------SGVDCERVDNPC-APQPC 324
N C C TC NT D Y+C C +GF GV C+ +D +PQPC
Sbjct: 51 NNCRDSTLCPAYATCTNTV-DSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 109
Query: 325 A-HGTC-SLAGTTR-----GFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDH 372
+ +C +L+G + GF+ W G S C + C +
Sbjct: 110 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 169
Query: 373 LDGFTCECADGWTGP-ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ ++C C G+ + EDVDEC+ C A CNNT G YSC C G+
Sbjct: 170 MGSYSCSCQVGFISRNSTCEDVDECADPRA-------CPEHATCNNTVGNYSCFCNPGFE 222
Query: 432 G-----------RDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL------ 474
CE ++D+CT C +TC + + C C G+A L
Sbjct: 223 SSSGHLSFQGLKASCE-DIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQG 281
Query: 475 ----DVDDCAPRPCTNGGE--CVDLLNAYRCICPVGF 505
D+D+C P T G C + L +Y C C GF
Sbjct: 282 VECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 318
Score = 87.8 bits (208), Expect = 2e-16
Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 49/224 (21%)
Query: 363 CLHGASCRDHLDGFTCECADGWT-----------GPACAEDVDECSGRSMTEGALGPCVN 411
C A+C + +D + C C G+ G C +D+DECS PC
Sbjct: 59 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC-KDIDECSQSPQ------PCGP 111
Query: 412 AAACNNTAGGYSCACLAGW---TGRDCE---------TNVDDC--TGQCLHGATCIDLVD 457
++C N +G Y C+CL G+ TG D T++++C + C + C++ +
Sbjct: 112 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMG 171
Query: 458 DFHCACAAGYAGR--TCSLDVDDCA-PRPCTNGGECVDLLNAYRCICPVGFSGTN----- 509
+ C+C G+ R TC DVD+CA PR C C + + Y C C GF ++
Sbjct: 172 SYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSF 230
Query: 510 ------CEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKN 547
CED D C C + C Y+C C PG+ N
Sbjct: 231 QGLKASCEDI-DECT-EMCPINSTCTNTPGSYFCTCHPGFAPSN 272
Score = 80.6 bits (190), Expect = 3e-14
Identities = 60/215 (27%), Positives = 92/215 (42%), Gaps = 37/215 (17%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR-SMTEGALGPCVNAAACN---- 416
PC +SC++ + C C DG++ P + V G S T+ + C+ ++ C
Sbjct: 108 PCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTD--INECLTSSVCPEHSD 165
Query: 417 --NTAGGYSCACLAGWTGRD--CETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGR 470
N+ G YSC+C G+ R+ CE +VD+C C ATC + V ++ C C G+
Sbjct: 166 CVNSMGSYSCSCQVGFISRNSTCE-DVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 224
Query: 471 TCSL----------DVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCE--------- 511
+ L D+D+C C C + +Y C C GF+ +N +
Sbjct: 225 SGHLSFQGLKASCEDIDECTEM-CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 283
Query: 512 -DDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGW 543
D D C P CG + C A Y C C G+
Sbjct: 284 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 318
Score = 75.4 bits (177), Expect = 1e-12
Identities = 60/239 (25%), Positives = 91/239 (38%), Gaps = 37/239 (15%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C W G G + + L P A C NT Y CAC G+ + +
Sbjct: 30 CCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAY--ATCTNTVDSYYCACKQGFLSSNGQN 87
Query: 438 N----------VDDCTGQ---CLHGATCIDLVDDFHCACAAGYA------------GRTC 472
+ +D+C+ C ++C +L + C+C G++ G
Sbjct: 88 HFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFS 147
Query: 473 SLDVDDCAPRP-CTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGS-PCGNGAAC 528
D+++C C +CV+ + +Y C C VGF N CED D CA C A C
Sbjct: 148 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDV-DECADPRACPEHATC 206
Query: 529 YTAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+Y C C PG+ + + +C E+ + C E MC TC GS+
Sbjct: 207 NNTVGNYSCFCNPGFESSSGHLSFQGLKASC----EDIDECTE-MCPINSTCTNTPGSY 260
Score = 61.7 bits (143), Expect = 1e-08
Identities = 45/164 (27%), Positives = 64/164 (39%), Gaps = 34/164 (20%)
Query: 419 AGGYSCACLAGWTG-----RDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA--- 468
AG C + W G R T ++C C ATC + VD ++CAC G+
Sbjct: 25 AGRGGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSN 84
Query: 469 --------GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT---------- 508
G C D+D+C+ P+PC C +L Y+C C GFS
Sbjct: 85 GQNHFKDPGVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKP 143
Query: 509 ---NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+C D + S C + C + Y C C G+ +N T
Sbjct: 144 GNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST 187
Score = 41.9 bits (94), Expect = 0.011
Identities = 53/219 (24%), Positives = 72/219 (32%), Gaps = 55/219 (25%)
Query: 225 RPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNW--GGILCDQDLNYCGTH 282
+PG+ C S C + C + S+ C+C + C+ D++ C
Sbjct: 142 KPGNFSCTDINECLTSSVCPEHSDCVNSM---GSYSCSCQVGFISRNSTCE-DVDECADP 197
Query: 283 EPCQHGGTCENTAPDQYFCRCAEGF---SG--------VDCERVDNPCAPQPCAHGTCSL 331
C TC NT Y C C GF SG CE +D C + TC+
Sbjct: 198 RACPEHATCNNTV-GNYSCFCNPGFESSSGHLSFQGLKASCEDIDE-CTEMCPINSTCT- 254
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAE 391
T + CTC G+ G CRD
Sbjct: 255 -NTPGSYFCTCHPGFAPSNGQLNFTD-------QGVECRD-------------------- 286
Query: 392 DVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGW 430
+DEC T C + C N G YSC C+AG+
Sbjct: 287 -IDECRQDPST------CGPNSICTNALGSYSCGCIAGF 318
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/198 (31%), Positives = 85/198 (42%), Gaps = 25/198 (12%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNG 525
G C GG CV +C+CP GF+G++CE D D C+ C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECSEGIIECHNH 563
Query: 526 AACYTAQSDYYCHCAPGW 543
+ C Y+C C G+
Sbjct: 564 SRCVNLPGWYHCECRSGF 581
Score = 91.9 bits (218), Expect = 1e-17
Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 44/290 (15%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD-----CERVDNPCAPQPCAHGTCSL 331
N+C C C+N + C C G+ V CE +D A H
Sbjct: 393 NFCAEGPKCGENSECKNWNT-KATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVC 451
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGP----CLHGASCRDHLDGFTCECADGWTGP 387
+ C C G+ G C A C + + G +C C G+ G
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN 511
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG--- 444
C R+ E C C C C +G+TG CE ++D+C+
Sbjct: 512 GTI-----C--RAFCEEG---CRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGII 558
Query: 445 QCLHGATCIDLVDDFHCACAAGY--------AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
+C + + C++L +HC C +G+ +G +C +D+D+CA R C N C++L
Sbjct: 559 ECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC-IDIDECALRTHTCWNDSACINLA 617
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPG 542
+ C+CP SG +C D H G NG +T + D C C G
Sbjct: 618 GGFDCLCP---SGPSCSGDCPH-EGGLKHNGQV-WTLKEDRCSVCSCKDG 662
Score = 54.4 bits (125), Expect = 2e-06
Identities = 64/263 (24%), Positives = 103/263 (39%), Gaps = 45/263 (17%)
Query: 195 DKHCLPGWQGDN--CEKPVCKEGCHPTHGRCDRPGDCDCRPGW---RGELCSQCQPYPGC 249
+ C +G N E P C E + + C+C+ G+ +G+ + C+ C
Sbjct: 382 ENQCCRVCRGHNFCAEGPKCGENSECKNW--NTKATCECKSGYISVQGD-SAYCEDIDEC 438
Query: 250 --KHGYCNGSSWDCT------CDTNWGGILCDQ----DLNYCGTHEP-CQHGGTCENTAP 296
K YC+ ++ CD G I D + + CG+ + C C NT
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G + + C +G +A C C G+ G
Sbjct: 499 G-HSCTCKPGYVGNGT--ICRAFCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID 551
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGW--------TGPACAEDVDECSGRSMTEGAL 406
+ G C + + C + + CEC G+ +G +C D+DEC+ R+ T
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCI-DIDECALRTHT---- 606
Query: 407 GPCVNAAACNNTAGGYSCACLAG 429
C N +AC N AGG+ C C +G
Sbjct: 607 --CWNDSACINLAGGFDCLCPSG 627
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 27/169 (15%)
Query: 396 CSGRSMTEGALGP-CVNAAACNNTAGGYSCACLAGWTGRD-----CETNVDDCTGQ---C 446
C G + A GP C + C N +C C +G+ CE ++D+C + C
Sbjct: 389 CRGHNFC--AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYC 445
Query: 447 LHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCAP--RPCTNGGECVDLLNAYRCIC 501
C++L + C C GY +C+ + D+C C C + + + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCT-EHDECGSGQHNCDENAICTNTVQGHSCTC 504
Query: 502 PVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
G+ +GT C R C C G C C C G+TG +C
Sbjct: 505 KPGYVGNGTIC---RAFCEEG-CRYGGTCVAPNK---CVCPSGFTGSHC 546
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C G C N RCV GW+ CEC +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 677 W 677
+
Sbjct: 581 F 581
Score = 48.8 bits (111), Expect = 1e-04
Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 30/149 (20%)
Query: 445 QCLHGATCIDLVDDFHCACAAGYAG-----RTCSLDVDDCAPRP--CTNGGECVDLLNAY 497
+C + C + C C +GY C D+D+CA + C CV+L Y
Sbjct: 400 KCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLY 458
Query: 498 RCICPVGF---SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
RC C G+ +C + D C C A C + C C PG+ G RA
Sbjct: 459 RCDCVPGYIRVDDFSCTE-HDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRA 517
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCV 581
C EG C GGTCV
Sbjct: 518 F---------------CEEG-CRYGGTCV 530
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/198 (31%), Positives = 85/198 (42%), Gaps = 25/198 (12%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNG 525
G C GG CV +C+CP GF+G++CE D D C+ C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECSEGIIECHNH 563
Query: 526 AACYTAQSDYYCHCAPGW 543
+ C Y+C C G+
Sbjct: 564 SRCVNLPGWYHCECRSGF 581
Score = 91.9 bits (218), Expect = 1e-17
Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 44/290 (15%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD-----CERVDNPCAPQPCAHGTCSL 331
N+C C C+N + C C G+ V CE +D A H
Sbjct: 393 NFCAEGPKCGENSECKNWNT-KATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVC 451
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGP----CLHGASCRDHLDGFTCECADGWTGP 387
+ C C G+ G C A C + + G +C C G+ G
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN 511
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG--- 444
C R+ E C C C C +G+TG CE ++D+C+
Sbjct: 512 GTI-----C--RAFCEEG---CRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGII 558
Query: 445 QCLHGATCIDLVDDFHCACAAGY--------AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
+C + + C++L +HC C +G+ +G +C +D+D+CA R C N C++L
Sbjct: 559 ECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC-IDIDECALRTHTCWNDSACINLA 617
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPG 542
+ C+CP SG +C D H G NG +T + D C C G
Sbjct: 618 GGFDCLCP---SGPSCSGDCPH-EGGLKHNGQV-WTLKEDRCSVCSCKDG 662
Score = 54.4 bits (125), Expect = 2e-06
Identities = 64/263 (24%), Positives = 103/263 (39%), Gaps = 45/263 (17%)
Query: 195 DKHCLPGWQGDN--CEKPVCKEGCHPTHGRCDRPGDCDCRPGW---RGELCSQCQPYPGC 249
+ C +G N E P C E + + C+C+ G+ +G+ + C+ C
Sbjct: 382 ENQCCRVCRGHNFCAEGPKCGENSECKNW--NTKATCECKSGYISVQGD-SAYCEDIDEC 438
Query: 250 --KHGYCNGSSWDCT------CDTNWGGILCDQ----DLNYCGTHEP-CQHGGTCENTAP 296
K YC+ ++ CD G I D + + CG+ + C C NT
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G + + C +G +A C C G+ G
Sbjct: 499 G-HSCTCKPGYVGNGT--ICRAFCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID 551
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGW--------TGPACAEDVDECSGRSMTEGAL 406
+ G C + + C + + CEC G+ +G +C D+DEC+ R+ T
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCI-DIDECALRTHT---- 606
Query: 407 GPCVNAAACNNTAGGYSCACLAG 429
C N +AC N AGG+ C C +G
Sbjct: 607 --CWNDSACINLAGGFDCLCPSG 627
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 27/169 (15%)
Query: 396 CSGRSMTEGALGP-CVNAAACNNTAGGYSCACLAGWTGRD-----CETNVDDCTGQ---C 446
C G + A GP C + C N +C C +G+ CE ++D+C + C
Sbjct: 389 CRGHNFC--AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYC 445
Query: 447 LHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCAP--RPCTNGGECVDLLNAYRCIC 501
C++L + C C GY +C+ + D+C C C + + + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCT-EHDECGSGQHNCDENAICTNTVQGHSCTC 504
Query: 502 PVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
G+ +GT C R C C G C C C G+TG +C
Sbjct: 505 KPGYVGNGTIC---RAFCEEG-CRYGGTCVAPNK---CVCPSGFTGSHC 546
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C G C N RCV GW+ CEC +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 677 W 677
+
Sbjct: 581 F 581
Score = 48.8 bits (111), Expect = 1e-04
Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 30/149 (20%)
Query: 445 QCLHGATCIDLVDDFHCACAAGYAG-----RTCSLDVDDCAPRP--CTNGGECVDLLNAY 497
+C + C + C C +GY C D+D+CA + C CV+L Y
Sbjct: 400 KCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLY 458
Query: 498 RCICPVGF---SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
RC C G+ +C + D C C A C + C C PG+ G RA
Sbjct: 459 RCDCVPGYIRVDDFSCTE-HDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRA 517
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCV 581
C EG C GGTCV
Sbjct: 518 F---------------CEEG-CRYGGTCV 530
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/198 (31%), Positives = 85/198 (42%), Gaps = 25/198 (12%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNG 525
G C GG CV +C+CP GF+G++CE D D C+ C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECSEGIIECHNH 563
Query: 526 AACYTAQSDYYCHCAPGW 543
+ C Y+C C G+
Sbjct: 564 SRCVNLPGWYHCECRSGF 581
Score = 91.9 bits (218), Expect = 1e-17
Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 44/290 (15%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD-----CERVDNPCAPQPCAHGTCSL 331
N+C C C+N + C C G+ V CE +D A H
Sbjct: 393 NFCAEGPKCGENSECKNWNT-KATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVC 451
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGP----CLHGASCRDHLDGFTCECADGWTGP 387
+ C C G+ G C A C + + G +C C G+ G
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN 511
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG--- 444
C R+ E C C C C +G+TG CE ++D+C+
Sbjct: 512 GTI-----C--RAFCEEG---CRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGII 558
Query: 445 QCLHGATCIDLVDDFHCACAAGY--------AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
+C + + C++L +HC C +G+ +G +C +D+D+CA R C N C++L
Sbjct: 559 ECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC-IDIDECALRTHTCWNDSACINLA 617
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPG 542
+ C+CP SG +C D H G NG +T + D C C G
Sbjct: 618 GGFDCLCP---SGPSCSGDCPH-EGGLKHNGQV-WTLKEDRCSVCSCKDG 662
Score = 54.4 bits (125), Expect = 2e-06
Identities = 64/263 (24%), Positives = 103/263 (39%), Gaps = 45/263 (17%)
Query: 195 DKHCLPGWQGDN--CEKPVCKEGCHPTHGRCDRPGDCDCRPGW---RGELCSQCQPYPGC 249
+ C +G N E P C E + + C+C+ G+ +G+ + C+ C
Sbjct: 382 ENQCCRVCRGHNFCAEGPKCGENSECKNW--NTKATCECKSGYISVQGD-SAYCEDIDEC 438
Query: 250 --KHGYCNGSSWDCT------CDTNWGGILCDQ----DLNYCGTHEP-CQHGGTCENTAP 296
K YC+ ++ CD G I D + + CG+ + C C NT
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G + + C +G +A C C G+ G
Sbjct: 499 G-HSCTCKPGYVGNGT--ICRAFCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID 551
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGW--------TGPACAEDVDECSGRSMTEGAL 406
+ G C + + C + + CEC G+ +G +C D+DEC+ R+ T
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCI-DIDECALRTHT---- 606
Query: 407 GPCVNAAACNNTAGGYSCACLAG 429
C N +AC N AGG+ C C +G
Sbjct: 607 --CWNDSACINLAGGFDCLCPSG 627
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 27/169 (15%)
Query: 396 CSGRSMTEGALGP-CVNAAACNNTAGGYSCACLAGWTGRD-----CETNVDDCTGQ---C 446
C G + A GP C + C N +C C +G+ CE ++D+C + C
Sbjct: 389 CRGHNFC--AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYC 445
Query: 447 LHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCAP--RPCTNGGECVDLLNAYRCIC 501
C++L + C C GY +C+ + D+C C C + + + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCT-EHDECGSGQHNCDENAICTNTVQGHSCTC 504
Query: 502 PVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
G+ +GT C R C C G C C C G+TG +C
Sbjct: 505 KPGYVGNGTIC---RAFCEEG-CRYGGTCVAPNK---CVCPSGFTGSHC 546
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C G C N RCV GW+ CEC +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 677 W 677
+
Sbjct: 581 F 581
Score = 48.8 bits (111), Expect = 1e-04
Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 30/149 (20%)
Query: 445 QCLHGATCIDLVDDFHCACAAGYAG-----RTCSLDVDDCAPRP--CTNGGECVDLLNAY 497
+C + C + C C +GY C D+D+CA + C CV+L Y
Sbjct: 400 KCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLY 458
Query: 498 RCICPVGF---SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
RC C G+ +C + D C C A C + C C PG+ G RA
Sbjct: 459 RCDCVPGYIRVDDFSCTE-HDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRA 517
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCV 581
C EG C GGTCV
Sbjct: 518 F---------------CEEG-CRYGGTCV 530
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/198 (31%), Positives = 85/198 (42%), Gaps = 25/198 (12%)
Query: 359 ASGP-CLHGASCRDHLDGFTCECADGWTG----PACAEDVDECSGRSMTEGALGPCVNAA 413
A GP C + C++ TCEC G+ A ED+DEC+ + + C
Sbjct: 396 AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK------MHYCHANT 449
Query: 414 ACNNTAGGYSCACLAGWTGRD---CETNVDDC-TGQ--CLHGATCIDLVDDFHCACAAGY 467
C N G Y C C+ G+ D C T D+C +GQ C A C + V C C GY
Sbjct: 450 VCVNLPGLYRCDCVPGYIRVDDFSC-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
Query: 468 AGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGS--PCGNG 525
G C GG CV +C+CP GF+G++CE D D C+ C N
Sbjct: 509 VGNGTICRA--FCEEGCRYGGTCVA---PNKCVCPSGFTGSHCEKDIDECSEGIIECHNH 563
Query: 526 AACYTAQSDYYCHCAPGW 543
+ C Y+C C G+
Sbjct: 564 SRCVNLPGWYHCECRSGF 581
Score = 91.9 bits (218), Expect = 1e-17
Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 44/290 (15%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVD-----CERVDNPCAPQPCAHGTCSL 331
N+C C C+N + C C G+ V CE +D A H
Sbjct: 393 NFCAEGPKCGENSECKNWNT-KATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVC 451
Query: 332 AGTTRGFTCTCDRGWGGXXXXXXXXXXASGP----CLHGASCRDHLDGFTCECADGWTGP 387
+ C C G+ G C A C + + G +C C G+ G
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN 511
Query: 388 ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTG--- 444
C R+ E C C C C +G+TG CE ++D+C+
Sbjct: 512 GTI-----C--RAFCEEG---CRYGGTC---VAPNKCVCPSGFTGSHCEKDIDECSEGII 558
Query: 445 QCLHGATCIDLVDDFHCACAAGY--------AGRTCSLDVDDCAPRP--CTNGGECVDLL 494
+C + + C++L +HC C +G+ +G +C +D+D+CA R C N C++L
Sbjct: 559 ECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC-IDIDECALRTHTCWNDSACINLA 617
Query: 495 NAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSD--YYCHCAPG 542
+ C+CP SG +C D H G NG +T + D C C G
Sbjct: 618 GGFDCLCP---SGPSCSGDCPH-EGGLKHNGQV-WTLKEDRCSVCSCKDG 662
Score = 54.4 bits (125), Expect = 2e-06
Identities = 64/263 (24%), Positives = 103/263 (39%), Gaps = 45/263 (17%)
Query: 195 DKHCLPGWQGDN--CEKPVCKEGCHPTHGRCDRPGDCDCRPGW---RGELCSQCQPYPGC 249
+ C +G N E P C E + + C+C+ G+ +G+ + C+ C
Sbjct: 382 ENQCCRVCRGHNFCAEGPKCGENSECKNW--NTKATCECKSGYISVQGD-SAYCEDIDEC 438
Query: 250 --KHGYCNGSSWDCT------CDTNWGGILCDQ----DLNYCGTHEP-CQHGGTCENTAP 296
K YC+ ++ CD G I D + + CG+ + C C NT
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 297 DQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXXXX 356
+ C C G+ G + + C +G +A C C G+ G
Sbjct: 499 G-HSCTCKPGYVGNGT--ICRAFCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID 551
Query: 357 XXASG--PCLHGASCRDHLDGFTCECADGW--------TGPACAEDVDECSGRSMTEGAL 406
+ G C + + C + + CEC G+ +G +C D+DEC+ R+ T
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCI-DIDECALRTHT---- 606
Query: 407 GPCVNAAACNNTAGGYSCACLAG 429
C N +AC N AGG+ C C +G
Sbjct: 607 --CWNDSACINLAGGFDCLCPSG 627
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 27/169 (15%)
Query: 396 CSGRSMTEGALGP-CVNAAACNNTAGGYSCACLAGWTGRD-----CETNVDDCTGQ---C 446
C G + A GP C + C N +C C +G+ CE ++D+C + C
Sbjct: 389 CRGHNFC--AEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYC 445
Query: 447 LHGATCIDLVDDFHCACAAGYA---GRTCSLDVDDCAP--RPCTNGGECVDLLNAYRCIC 501
C++L + C C GY +C+ + D+C C C + + + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCT-EHDECGSGQHNCDENAICTNTVQGHSCTC 504
Query: 502 PVGF--SGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNC 548
G+ +GT C R C C G C C C G+TG +C
Sbjct: 505 KPGYVGNGTIC---RAFCEEG-CRYGGTCVAPNK---CVCPSGFTGSHC 546
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 619 GGTCLPSALPPGWACGCREGRTGALCELSLDLC--GSSPCRNGGRCVGGSGWWMCECVAG 676
GGTC+ P C C G TG+ CE +D C G C N RCV GW+ CEC +G
Sbjct: 526 GGTCVA----PN-KCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Query: 677 W 677
+
Sbjct: 581 F 581
Score = 48.8 bits (111), Expect = 1e-04
Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 30/149 (20%)
Query: 445 QCLHGATCIDLVDDFHCACAAGYAG-----RTCSLDVDDCAPRP--CTNGGECVDLLNAY 497
+C + C + C C +GY C D+D+CA + C CV+L Y
Sbjct: 400 KCGENSECKNWNTKATCECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLY 458
Query: 498 RCICPVGF---SGTNCEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGWTGKNCTQRA 552
RC C G+ +C + D C C A C + C C PG+ G RA
Sbjct: 459 RCDCVPGYIRVDDFSCTE-HDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRA 517
Query: 553 ARDRKTCSVLVEESERCAEGMCANGGTCV 581
C EG C GGTCV
Sbjct: 518 F---------------CEEG-CRYGGTCV 530
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 94.3 bits (224), Expect = 2e-18
Identities = 77/276 (27%), Positives = 111/276 (40%), Gaps = 55/276 (19%)
Query: 277 NYCGTHEPCQHGGTCENTAPDQYFCRCAEGF-----------SGVDCERVDNPC-APQPC 324
N C C TC NT D Y+C C +GF GV C+ +D +PQPC
Sbjct: 33 NNCRDSTLCPAYATCTNTV-DSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
Query: 325 A-HGTC-SLAGTTR-----GFTCTCDRGW-----GGXXXXXXXXXXASGPCLHGASCRDH 372
+ +C +L+G + GF+ W G S C + C +
Sbjct: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNS 151
Query: 373 LDGFTCECADGWTGP-ACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
+ ++C C G+ + EDV+EC+ C A CNNT G YSC C G+
Sbjct: 152 MGSYSCSCQVGFISRNSTCEDVNECADPRA-------CPEHATCNNTVGNYSCFCNPGFE 204
Query: 432 GR----DCE------TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSL------- 474
C+ ++D+CT C +TC + + C C G+A + L
Sbjct: 205 SSSGHLSCQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGV 264
Query: 475 ---DVDDCAPRPCTNGGE--CVDLLNAYRCICPVGF 505
D+D+C P T G C + L +Y C C VGF
Sbjct: 265 ECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGF 300
Score = 77.4 bits (182), Expect = 2e-13
Identities = 60/216 (27%), Positives = 90/216 (41%), Gaps = 39/216 (18%)
Query: 362 PCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGR-SMTEGALGPCVNAAACN---- 416
PC +SC++ + C C DG++ P + V G S T+ + C+ + C
Sbjct: 90 PCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTD--INECLTSRVCPEHSD 147
Query: 417 --NTAGGYSCACLAGWTGRD--CETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYAGR 470
N+ G YSC+C G+ R+ CE +V++C C ATC + V ++ C C G+
Sbjct: 148 CVNSMGSYSCSCQVGFISRNSTCE-DVNECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
Query: 471 TCSL----------DVDDCAPRPCTNGGECVDLLNAYRCICPVGFS-----------GTN 509
+ L D+D+C C C + +Y C C GF+ G
Sbjct: 207 SGHLSCQGLKASCEDIDECTEM-CPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVE 265
Query: 510 CEDDRDHCAGSP--CGNGAACYTAQSDYYCHCAPGW 543
C D D C P CG + C A Y C C G+
Sbjct: 266 CRDI-DECRQDPSTCGPNSICTNALGSYSCGCIVGF 300
Score = 76.6 bits (180), Expect = 4e-13
Identities = 57/238 (23%), Positives = 89/238 (37%), Gaps = 35/238 (14%)
Query: 378 CECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCET 437
C W G G + + L P A C NT Y C C G+ + +
Sbjct: 12 CCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAY--ATCTNTVDSYYCTCKQGFLSSNGQN 69
Query: 438 N----------VDDCTGQ---CLHGATCIDLVDDFHCACAAGYA------------GRTC 472
+ +D+C+ C ++C +L + C+C G++ G
Sbjct: 70 HFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFS 129
Query: 473 SLDVDDC-APRPCTNGGECVDLLNAYRCICPVGFSGTN--CEDDRDHCAGSPCGNGAACY 529
D+++C R C +CV+ + +Y C C VGF N CED + C A C
Sbjct: 130 CTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVNECADPRACPEHATCN 189
Query: 530 TAQSDYYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSW 587
+Y C C PG+ + + +C E+ + C E MC TC GS+
Sbjct: 190 NTVGNYSCFCNPGFESSSGHLSCQGLKASC----EDIDECTE-MCPINSTCTNTPGSY 242
Score = 56.8 bits (131), Expect = 4e-07
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 34/161 (21%)
Query: 422 YSCACLAGWTG-----RDCETNVDDCTGQ--CLHGATCIDLVDDFHCACAAGYA------ 468
+ C + W G R T ++C C ATC + VD ++C C G+
Sbjct: 10 WGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQN 69
Query: 469 -----GRTCSLDVDDCA--PRPCTNGGECVDLLNAYRCICPVGFSGT------------- 508
G C D+D+C+ P+PC C +L Y+C C GFS
Sbjct: 70 HFKDPGVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNF 128
Query: 509 NCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCT 549
+C D + C + C + Y C C G+ +N T
Sbjct: 129 SCTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGFISRNST 169
Score = 41.5 bits (93), Expect = 0.014
Identities = 50/196 (25%), Positives = 65/196 (33%), Gaps = 54/196 (27%)
Query: 250 KHGYCNGS--SWDCTCDTNW--GGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAE 305
+H C S S+ C+C + C+ D+N C C TC NT Y C C
Sbjct: 144 EHSDCVNSMGSYSCSCQVGFISRNSTCE-DVNECADPRACPEHATCNNTV-GNYSCFCNP 201
Query: 306 GF---SG--------VDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGXXXXXX 354
GF SG CE +D C + TC+ T + CTC G+
Sbjct: 202 GFESSSGHLSCQGLKASCEDIDE-CTEMCPINSTCT--NTPGSYFCTCHPGFAPSSGQLN 258
Query: 355 XXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAA 414
G CR D+DEC T C +
Sbjct: 259 FTD-------QGVECR---------------------DIDECRQDPST------CGPNSI 284
Query: 415 CNNTAGGYSCACLAGW 430
C N G YSC C+ G+
Sbjct: 285 CTNALGSYSCGCIVGF 300
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 93.1 bits (221), Expect = 4e-18
Identities = 97/354 (27%), Positives = 142/354 (40%), Gaps = 62/354 (17%)
Query: 275 DLNYCGTH-EPCQHGGTCENTAPDQYFC----RCAEGFSGVD--CERVDNPCA--PQPCA 325
D+N C T C G C NT + C C G++ D CE VD CA C
Sbjct: 766 DINECVTDLHTCSRGEHCVNTL-GSFHCYKALTCEPGYALKDGECEDVDE-CAMGTHTCQ 823
Query: 326 HGTCSLAGTTRG-FTCT----CDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLDGF 376
G L T+G F C C G+ G S PC G SC + + +
Sbjct: 824 PGF--LCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSY 881
Query: 377 TCE-----CADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWT 431
TC+ CA G+ ++D +C + E + C C+N G Y C C AG+
Sbjct: 882 TCQRNPLICARGYHA---SDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ 938
Query: 432 ----GRDCETNVDDCTGQ----CLHGATCIDLVDDFHCACAAGYA----GRTCSLDVDDC 479
GR C +V++C C H TC + + + C+CA+G+ G+ C DV++C
Sbjct: 939 RDAFGRGC-IDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCE-DVNEC 994
Query: 480 APRPCTNGGECVDLLNAYRCICPVGF----SGTNCEDDRDHCA-GSPCGNGAACYTAQSD 534
+ C+ EC ++ +Y+C C G+ G C D D CA G+ C
Sbjct: 995 EAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTC-TDIDECAQGAGILCTFRCLNVPGS 1051
Query: 535 YYCHCAPGWTGKNCTQRAARDRKTCSVLVEESERCAEGMCANGGTCVREEGSWR 588
Y C C R+ +D C++ C+ TC +GS+R
Sbjct: 1052 YQCACPEQGYTMTANGRSCKDVDECALGTHN--------CSEAETCHNIQGSFR 1097
Score = 54.8 bits (126), Expect = 1e-06
Identities = 81/297 (27%), Positives = 117/297 (39%), Gaps = 57/297 (19%)
Query: 165 CQPNYY--NTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEG--CHPTH 220
CQP + NT + +C+ R + P+G+ C+ + + +P C+ G C T
Sbjct: 822 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINECTSLSEP-CRPGFSCINTV 878
Query: 221 GR--CDRPGDCDCRPGWR----GELC---SQCQP-YPGCKHGY-CNG--SSWDCTCDTNW 267
G C R C G+ G C ++C+ C G C+ S+ C C +
Sbjct: 879 GSYTCQR-NPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 937
Query: 268 GGILCDQ---DLNYCGTHEP--CQHGGTCENTAPDQYFCRCAEGF----SGVDCERVDNP 318
+ D+N C CQH TCENT Y C CA GF G CE V N
Sbjct: 938 QRDAFGRGCIDVNECWASPGRLCQH--TCENTL-GSYRCSCASGFLLAADGKRCEDV-NE 993
Query: 319 CAPQPCAHGTCSLAGTTRGFTCTCDRGW----GGXXXXXXXXXXASGPCLHGASCRDHLD 374
C Q C+ ++ G+ + C C +G+ G L C +
Sbjct: 994 CEAQRCSQECANIYGS---YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPG 1050
Query: 375 GFTCECAD-GWT----GPACAEDVDECSGRSMTEGALGP--CVNAAACNNTAGGYSC 424
+ C C + G+T G +C +DVDEC ALG C A C+N G + C
Sbjct: 1051 SYQCACPEQGYTMTANGRSC-KDVDEC--------ALGTHNCSEAETCHNIQGSFRC 1098
>AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein.
Length = 744
Score = 93.1 bits (221), Expect = 4e-18
Identities = 102/357 (28%), Positives = 125/357 (35%), Gaps = 75/357 (21%)
Query: 183 DKFGHYSC---TPDGDKHCLPGWQ--GDNCEKPVCK--EGCHPTHGRCDRPGDCDCRPGW 235
D G + C +P + C GW+ C P+C+ + C C +PG C C+PG+
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEV-CVKPGLCRCKPGF 81
Query: 236 RGELCSQCQP--Y--PGCK-------HGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEP 284
G CS P Y P C+ HG C ++ C C + G C+ CG H
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-ACGPH-- 138
Query: 285 CQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDR 344
G C+ P C C G+ C R PC T + C C
Sbjct: 139 ----GRCD---PATGVCHCEPGWWSSTCRR--------PCQCNTAAARCEQATGACVCKP 183
Query: 345 GWGGXXXXXXXXXXASGPC-LHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTE 403
GW G S C HG+ C D C C GW GP C + EC R
Sbjct: 184 GWWG--------RRCSFRCNCHGSPCEQ--DSGRCACRPGWWGPECQQQC-ECV-RGRCS 231
Query: 404 GALGPCVNAAACNNTAGGYSC--ACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHC 461
A G C C G C C AG G C C G+C H C D C
Sbjct: 232 AASGEC----TCPPGFRGARCELPCPAGSHGVQC---AHSC-GRCKHNEPCSP--DTGSC 281
Query: 462 -ACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHC 517
+C G+ G C C P T G C CP G CE D HC
Sbjct: 282 ESCEPGWNGTQCQ---QPCLPG--TFGESCEQQ-------CPHCRHGEACEPDTGHC 326
Score = 77.4 bits (182), Expect = 2e-13
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 21/164 (12%)
Query: 165 CQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCD 224
C+P ++++TC C+ T G C PGW G C + CH + D
Sbjct: 150 CEPGWWSSTCRRPCQCNTAAARCEQAT--GACVCKPGWWGRRCS---FRCNCHGSPCEQD 204
Query: 225 RPGDCDCRPGWRGELCSQ-CQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTH- 282
G C CRPGW G C Q C+ C G C+ +S +CTC + G C+ G+H
Sbjct: 205 S-GRCACRPGWWGPECQQQCE----CVRGRCSAASGECTCPPGFRGARCELPCP-AGSHG 258
Query: 283 EPCQHG-GTC---ENTAPDQYFCR-CAEGFSGVDCERVDNPCAP 321
C H G C E +PD C C G++G C++ PC P
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ---PCLP 299
Score = 71.3 bits (167), Expect = 2e-11
Identities = 84/281 (29%), Positives = 95/281 (33%), Gaps = 57/281 (20%)
Query: 279 CGTHEPCQHGGTCENTAPDQY--FC--RCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGT 334
C E C G C P + C RC + G DC R PC P HG C A
Sbjct: 63 CQKDEVCVKPGLCR-CKPGFFGAHCSSRCPGQYWGPDC-RESCPCHP----HGQCEPA-- 114
Query: 335 TRGFTCTCDRGWGGXXXXXXXXXXASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVD 394
T C DR WG A GP HG C D G C C GW C
Sbjct: 115 TGACQCQADR-WGARCEFPC----ACGP--HGR-C-DPATG-VCHCEPGWWSSTCRRPC- 163
Query: 395 ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCID 454
+C+ AA C G +C C GW GR C + C HG+ C
Sbjct: 164 QCN------------TAAARCEQATG--ACVCKPGWWGRRCSFRCN-----C-HGSPCEQ 203
Query: 455 LVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECV--DLLNAYRCI--CPVGFSGTNC 510
D CAC G+ G C + R GEC RC CP G G C
Sbjct: 204 --DSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQC 261
Query: 511 EDDRDHCA-GSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQ 550
C PC + +S C PGW G C Q
Sbjct: 262 AHSCGRCKHNEPCSPDTG--SCES-----CEPGWNGTQCQQ 295
Score = 53.2 bits (122), Expect = 4e-06
Identities = 59/207 (28%), Positives = 68/207 (32%), Gaps = 37/207 (17%)
Query: 378 CECADGWTGPACAEDVD-ECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCE 436
C C G+ G C+ + G E PC C G +C C A G CE
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESC--PCHPHGQCEPATG--ACQCQADRWGARCE 130
Query: 437 TNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPC---TNGGECVDL 493
C C C C C G+ TC RPC T C
Sbjct: 131 F---PCA--CGPHGRCDPATGV--CHCEPGWWSSTCR--------RPCQCNTAAARCEQA 175
Query: 494 LNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAA 553
A C+C G+ G C R +C GSPC Q C C PGW G C Q+
Sbjct: 176 TGA--CVCKPGWWGRRCSF-RCNCHGSPC--------EQDSGRCACRPGWWGPECQQQCE 224
Query: 554 RDRKTCSVLVEESERCAEGMCANGGTC 580
R CS E C G G C
Sbjct: 225 CVRGRCSAASGEC-TCPPGF--RGARC 248
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 632 ACGCREGRTGALCELSLDLCGSSPC-RNGGRCVGGSGWW------MCECVAG 676
AC C+ G G C + C SPC ++ GRC GWW CECV G
Sbjct: 178 ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 8/55 (14%)
Query: 628 PPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETC 682
P AC C+ R GA CE C P GRC +G +C C GW TC
Sbjct: 113 PATGACQCQADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTC 159
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.138 0.500
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 151,296,406
Number of Sequences: 224733
Number of extensions: 7216545
Number of successful extensions: 56416
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 674
Number of HSP's successfully gapped in prelim test: 718
Number of HSP's that attempted gapping in prelim test: 13798
Number of HSP's gapped (non-prelim): 16859
length of query: 996
length of database: 73,234,838
effective HSP length: 97
effective length of query: 899
effective length of database: 51,435,737
effective search space: 46240727563
effective search space used: 46240727563
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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