Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000779-TA|BGIBMGA000779-PA|IPR002219|Protein kinase C,
phorbol ester/diacylglycerol binding, IPR000719|Protein kinase,
IPR000961|Protein kinase, C-terminal, IPR011009|Protein kinase-like,
IPR008271|Serine/threonine protein kinase, active site,
IPR002290|Serine/threonine protein kinase
(660 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 663 0.0
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 663 0.0
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 663 0.0
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 510 e-144
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 510 e-144
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 510 e-144
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 510 e-144
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 510 e-144
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 509 e-143
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 450 e-126
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 447 e-125
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 426 e-118
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 425 e-118
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 425 e-118
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 425 e-118
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 421 e-117
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 421 e-117
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 421 e-117
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 421 e-117
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 413 e-115
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 413 e-115
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 409 e-113
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 394 e-109
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 394 e-109
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 394 e-109
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 386 e-106
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 377 e-104
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 377 e-104
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 363 1e-99
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 363 1e-99
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 363 1e-99
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 359 2e-98
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 352 2e-96
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 352 3e-96
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 352 3e-96
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 343 2e-93
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 343 2e-93
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 341 4e-93
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 323 1e-87
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 323 1e-87
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 323 1e-87
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 322 2e-87
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 311 5e-84
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 311 5e-84
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 311 5e-84
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 311 6e-84
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 311 6e-84
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 311 6e-84
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 311 6e-84
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 311 6e-84
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 311 6e-84
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 311 6e-84
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 308 3e-83
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 305 2e-82
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 304 7e-82
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 304 7e-82
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 304 7e-82
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 303 9e-82
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 301 4e-81
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 301 4e-81
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 301 4e-81
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 301 4e-81
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 299 1e-80
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 297 1e-79
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 297 1e-79
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 297 1e-79
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 297 1e-79
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 297 1e-79
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 297 1e-79
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 297 1e-79
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 297 1e-79
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 297 1e-79
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 297 1e-79
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 295 4e-79
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 292 2e-78
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 291 4e-78
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 291 4e-78
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 289 2e-77
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 288 5e-77
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 288 5e-77
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 288 5e-77
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 288 5e-77
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 288 5e-77
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 288 5e-77
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 285 3e-76
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 285 5e-76
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 284 6e-76
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 284 6e-76
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 284 6e-76
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 284 6e-76
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 284 6e-76
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 261 5e-69
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 261 5e-69
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 261 5e-69
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 254 7e-67
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 254 7e-67
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 254 7e-67
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 254 7e-67
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 254 7e-67
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 252 3e-66
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 247 1e-64
AC017078-1|AAY14773.1| 238|Homo sapiens unknown protein. 245 3e-64
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 243 1e-63
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 243 1e-63
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 243 1e-63
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 243 1e-63
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 243 1e-63
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 243 1e-63
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 240 1e-62
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 237 7e-62
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 237 7e-62
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 237 7e-62
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 237 7e-62
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 236 2e-61
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 236 2e-61
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 235 3e-61
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 235 3e-61
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 235 4e-61
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 235 4e-61
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 235 4e-61
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 235 4e-61
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 235 4e-61
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 235 4e-61
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 235 4e-61
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 235 4e-61
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 235 4e-61
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 235 4e-61
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 235 4e-61
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 235 4e-61
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 235 4e-61
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 235 5e-61
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 235 5e-61
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 235 5e-61
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 235 5e-61
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 235 5e-61
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 234 6e-61
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 234 8e-61
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 234 8e-61
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 234 8e-61
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 233 1e-60
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 233 1e-60
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 233 1e-60
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 233 1e-60
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 229 2e-59
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 229 2e-59
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 227 7e-59
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 220 1e-56
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 219 2e-56
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 219 2e-56
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 219 2e-56
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 219 2e-56
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 217 1e-55
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 217 1e-55
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 208 4e-53
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 207 8e-53
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 207 8e-53
AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein. 207 8e-53
AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein. 207 8e-53
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 207 1e-52
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 207 1e-52
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 207 1e-52
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 207 1e-52
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 207 1e-52
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 207 1e-52
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 207 1e-52
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 207 1e-52
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 206 1e-52
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 206 1e-52
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 203 2e-51
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 203 2e-51
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 203 2e-51
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 203 2e-51
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 203 2e-51
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 197 9e-50
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 196 2e-49
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 196 2e-49
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 196 2e-49
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 196 2e-49
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 196 2e-49
U33168-4|AAC50412.1| 500|Homo sapiens G protein-coupled recepto... 196 2e-49
U33168-3|AAC50409.1| 546|Homo sapiens G protein-coupled recepto... 196 2e-49
U33168-2|AAC50411.1| 532|Homo sapiens G protein-coupled recepto... 196 2e-49
U33168-1|AAC50410.1| 578|Homo sapiens G protein-coupled recepto... 196 2e-49
X98118-1|CAA66802.1| 532|Homo sapiens G protein-coupled recepto... 196 3e-49
X97881-1|CAA66470.1| 578|Homo sapiens G-protein coupled recepto... 196 3e-49
X97880-1|CAA66469.1| 546|Homo sapiens G-protein coupled recepto... 196 3e-49
X97879-1|CAA66468.1| 500|Homo sapiens G-protein coupled recepto... 196 3e-49
U33056-1|AAC50408.1| 532|Homo sapiens G protein-coupled recepto... 196 3e-49
U33055-1|AAC50407.1| 546|Homo sapiens G protein-coupled recepto... 196 3e-49
U33054-1|AAC50406.1| 578|Homo sapiens G protein-coupled recepto... 196 3e-49
L03718-1|AAB04045.1| 500|Homo sapiens G protein-coupled recepto... 196 3e-49
BC117320-1|AAI17321.1| 578|Homo sapiens G protein-coupled recep... 196 3e-49
AK223581-1|BAD97301.1| 500|Homo sapiens G protein-coupled recep... 196 3e-49
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 192 3e-48
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 192 3e-48
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 192 3e-48
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 192 3e-48
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 192 3e-48
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 192 3e-48
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 192 3e-48
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 192 3e-48
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 192 3e-48
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 192 3e-48
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 192 3e-48
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 192 3e-48
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 192 3e-48
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 192 4e-48
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 192 4e-48
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 192 4e-48
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 192 4e-48
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein k... 192 4e-48
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 192 4e-48
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 192 4e-48
S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase p... 191 8e-48
M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein. 191 8e-48
L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein. 191 8e-48
L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase... 191 8e-48
L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase... 191 8e-48
L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase... 191 8e-48
L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase... 191 8e-48
L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase, ... 191 8e-48
L00727-3|AAA75239.1| 634|Homo sapiens myotonin-protein kinase, ... 191 8e-48
L00727-2|AAA75238.1| 609|Homo sapiens myotonin-protein kinase, ... 191 8e-48
L00727-1|AAA75236.1| 639|Homo sapiens myotonin-protein kinase, ... 191 8e-48
BC062553-1|AAH62553.1| 629|Homo sapiens DMPK protein protein. 191 8e-48
BC026328-1|AAH26328.1| 655|Homo sapiens DMPK protein protein. 191 8e-48
AB209363-1|BAD92600.1| 672|Homo sapiens myotonic dystrophy prot... 191 8e-48
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 188 4e-47
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 188 4e-47
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 188 4e-47
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 188 4e-47
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 188 4e-47
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 188 4e-47
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 188 4e-47
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 187 1e-46
L15388-1|AAA58620.1| 590|Homo sapiens G protein-coupled recepto... 187 1e-46
BC064506-1|AAH64506.1| 590|Homo sapiens G protein-coupled recep... 187 1e-46
AL583824-2|CAI16759.1| 590|Homo sapiens G protein-coupled recep... 187 1e-46
AL355861-4|CAI15804.1| 590|Homo sapiens G protein-coupled recep... 187 1e-46
AL355273-2|CAI16487.1| 590|Homo sapiens G protein-coupled recep... 187 1e-46
S74620-1|AAB32724.1| 102|Homo sapiens protein kinase C eta b pr... 186 2e-46
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 186 2e-46
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 186 2e-46
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 186 2e-46
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 185 4e-46
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 185 4e-46
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 185 4e-46
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 184 1e-45
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 184 1e-45
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 184 1e-45
U00686-1|AAA03565.1| 544|Homo sapiens putative novel receptor k... 181 6e-45
L16862-1|AAA60175.1| 576|Homo sapiens G protein-coupled recepto... 181 6e-45
BC009277-1|AAH09277.1| 576|Homo sapiens G protein-coupled recep... 181 6e-45
AF040752-1|AAC09274.1| 560|Homo sapiens G protein-coupled recep... 181 6e-45
AF040751-1|AAC09273.1| 589|Homo sapiens G protein-coupled recep... 181 6e-45
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 181 8e-45
BC017272-1|AAH17272.1| 589|Homo sapiens G protein-coupled recep... 180 2e-44
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 179 3e-44
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 179 3e-44
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 179 3e-44
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 179 3e-44
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 179 3e-44
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 179 3e-44
Z22521-1|CAA80249.1| 365|Homo sapiens protein kinase C delta pr... 178 4e-44
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 177 1e-43
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 177 1e-43
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 175 3e-43
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 174 7e-43
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 174 7e-43
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 174 9e-43
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 173 1e-42
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 173 2e-42
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 173 2e-42
AF439409-1|AAL48216.1| 553|Homo sapiens G-protein-coupled recep... 172 4e-42
AF282269-1|AAL33880.1| 553|Homo sapiens G protein-coupled recep... 172 4e-42
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 171 5e-42
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 171 5e-42
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 171 5e-42
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 171 5e-42
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 171 5e-42
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 171 5e-42
L00727-6|AAA75240.1| 540|Homo sapiens myotonin-protein kinase, ... 170 2e-41
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 169 3e-41
M13977-1|AAA60102.1| 317|Homo sapiens protein kinase C-gamma pr... 168 5e-41
AB209671-1|BAD92908.1| 239|Homo sapiens protein kinase C, gamma... 168 5e-41
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 168 6e-41
BC001737-1|AAH01737.1| 201|Homo sapiens Unknown (protein for IM... 167 1e-40
BC053321-1|AAH53321.1| 380|Homo sapiens PRKCA protein protein. 164 8e-40
M22199-1|AAA60098.1| 431|Homo sapiens PRKACA protein. 160 1e-38
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 159 2e-38
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 159 2e-38
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 159 2e-38
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 159 2e-38
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 159 2e-38
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 159 2e-38
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 159 2e-38
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 159 2e-38
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 159 3e-38
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 159 3e-38
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 159 4e-38
Y12337-1|CAA73006.1| 289|Homo sapiens myotonic dystrophy protei... 157 2e-37
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 156 3e-37
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 155 4e-37
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 155 4e-37
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 155 4e-37
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 155 4e-37
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 155 4e-37
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 155 4e-37
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 154 8e-37
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 154 8e-37
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 154 8e-37
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 154 8e-37
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 154 8e-37
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 154 8e-37
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 154 8e-37
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 154 8e-37
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 154 1e-36
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 154 1e-36
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 154 1e-36
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 154 1e-36
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 154 1e-36
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 154 1e-36
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 154 1e-36
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 154 1e-36
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 154 1e-36
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 154 1e-36
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 154 1e-36
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 154 1e-36
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 154 1e-36
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 153 1e-36
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 153 1e-36
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 153 2e-36
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 153 3e-36
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 152 4e-36
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 152 4e-36
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 152 4e-36
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 151 8e-36
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 151 1e-35
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 151 1e-35
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 151 1e-35
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 149 2e-35
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 149 2e-35
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 149 4e-35
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 149 4e-35
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 149 4e-35
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 149 4e-35
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 149 4e-35
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 149 4e-35
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 149 4e-35
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 149 4e-35
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 149 4e-35
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 148 7e-35
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 148 7e-35
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 148 7e-35
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 148 7e-35
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 148 7e-35
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 147 9e-35
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 147 9e-35
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 147 1e-34
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 147 1e-34
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 146 2e-34
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 146 3e-34
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 144 7e-34
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 144 7e-34
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 144 7e-34
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 144 7e-34
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 144 1e-33
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 144 1e-33
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 144 1e-33
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 144 1e-33
AY358353-1|AAQ88719.1| 364|Homo sapiens HSA250839 protein. 144 1e-33
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 144 1e-33
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 143 2e-33
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 143 2e-33
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 143 2e-33
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 143 2e-33
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 143 2e-33
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 143 2e-33
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 143 2e-33
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 142 5e-33
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 142 5e-33
AL512622-5|CAI12187.1| 369|Homo sapiens protein kinase (PKE) pr... 141 6e-33
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 141 8e-33
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 140 1e-32
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 140 1e-32
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 140 1e-32
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 140 1e-32
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 140 2e-32
BC120995-1|AAI20996.1| 438|Homo sapiens AKT2 protein protein. 140 2e-32
BC045760-1|AAH45760.1| 369|Homo sapiens STK32C protein protein. 139 2e-32
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 139 3e-32
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 139 3e-32
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 138 4e-32
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 138 6e-32
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 138 6e-32
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 138 6e-32
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 138 6e-32
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 138 6e-32
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 138 6e-32
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 138 6e-32
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 138 8e-32
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 138 8e-32
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 137 1e-31
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 134 7e-31
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 134 7e-31
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 134 7e-31
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 133 2e-30
BC036797-1|AAH36797.1| 387|Homo sapiens ADRBK2 protein protein. 133 2e-30
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 133 2e-30
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 133 2e-30
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 133 2e-30
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 133 2e-30
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 131 7e-30
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 130 1e-29
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 130 2e-29
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 130 2e-29
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 130 2e-29
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 130 2e-29
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 130 2e-29
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 130 2e-29
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 130 2e-29
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 129 3e-29
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 129 4e-29
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 129 4e-29
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 129 4e-29
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 129 4e-29
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 128 6e-29
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 128 6e-29
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 128 6e-29
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 128 6e-29
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 127 1e-28
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 127 1e-28
AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant ... 127 1e-28
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 127 1e-28
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 126 2e-28
AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase pr... 126 2e-28
AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor ... 126 2e-28
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 126 2e-28
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 126 3e-28
BC009107-1|AAH09107.1| 879|Homo sapiens microtubule associated ... 126 3e-28
AL160291-7|CAI16908.1| 878|Homo sapiens novel protein kinase do... 126 3e-28
AL160291-6|CAI16909.1| 879|Homo sapiens novel protein kinase do... 126 3e-28
AL160291-5|CAI16910.1| 840|Homo sapiens novel protein kinase do... 126 3e-28
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 126 3e-28
AK074804-1|BAC11218.1| 840|Homo sapiens protein ( Homo sapiens ... 126 3e-28
AK027719-1|BAB55321.1| 878|Homo sapiens protein ( Homo sapiens ... 126 3e-28
AL356285-1|CAI15861.1| 1088|Homo sapiens LATS, large tumor suppr... 125 4e-28
AL161613-1|CAH71526.1| 1088|Homo sapiens LATS, large tumor suppr... 125 4e-28
AB209897-1|BAD93134.1| 924|Homo sapiens LATS, large tumor suppr... 125 4e-28
AB028019-1|BAA92381.1| 1046|Homo sapiens large tumor suppressor ... 125 4e-28
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 125 6e-28
AF207547-1|AAF80561.1| 1088|Homo sapiens serine/threonine kinase... 125 6e-28
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 124 1e-27
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 124 1e-27
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 123 2e-27
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 123 2e-27
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 123 2e-27
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 123 2e-27
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 123 2e-27
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 123 2e-27
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 123 2e-27
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 123 2e-27
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 123 2e-27
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 122 4e-27
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 122 4e-27
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 122 5e-27
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 121 7e-27
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 121 7e-27
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 663 bits (1637), Expect = 0.0
Identities = 340/658 (51%), Positives = 418/658 (63%), Gaps = 61/658 (9%)
Query: 23 VDLEPQGKLHLKIDLKWHSQXXXXXXXXXXXXXXXXXXXXXAPREFKEXXXXXXXXXXXX 82
+DLEP+G++++ IDL S R F+E
Sbjct: 117 IDLEPEGRVYVIIDLSGSS---------------GEAPKDNEERVFRERMRPRKRQGAVR 161
Query: 83 XXVHQVNGHKFMATFLRQPTFCSLCREFIWG-IGKQGYQCQVCTCVLHKRCHSLIVTKCP 141
VHQVNGHKFMAT+LRQPT+CS CR+FIWG IGKQGYQCQVCTCV+HKRCH LI+TKC
Sbjct: 162 RRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 221
Query: 142 GMKEEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVH 200
G+K++ VG Q FSVN+PH+F +H+YK TFCDHCGSLL+GL++QGLQC+ C MNVH
Sbjct: 222 GLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVH 281
Query: 201 KRCQKNVANNCGTNTKAMAALLNEMGISPDK-----NPRPKTFKVTSSPQLPSPPTHCVT 255
+RC+ NVA NCG + + +A +L ++G++PDK R K SPQ S +
Sbjct: 282 RRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEE 341
Query: 256 RLSHPQYLNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLKKPSLEDFT---FIK 312
S +P + G L P K
Sbjct: 342 DRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAK 401
Query: 313 VLGKGSFGKVMLAERRGTEEVFAVKVLKKDAI-----------LQDDDAECTXXXXXXXX 361
LG F + + + +V ++ KD + LQDDD +CT
Sbjct: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HP+LT L+C FQT+DRLFFVMEYV+GGDLMFQIQR+RKFDEPR+RFYAAEVT AL
Sbjct: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALM 521
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
FLH+HGVIYRDLKLDNILLD+EGHCKLADFGMCKEGI++GVTTTTFCGTPDYIAPEILQE
Sbjct: 522 FLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
EYG SVDWWALGVL+YEM+AGQPPFEADNEDDLFESILHDDVLYPVWLS++AVSILK F
Sbjct: 582 LEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAF 641
Query: 542 MTKAPSRRLGVC---GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
MTK P +RLG G IK H FF+++DW L Q+K++PPF+P++
Sbjct: 642 MTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRI------------ 689
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
K+KR+ NFD +FT+EEPVLT V +++ INQEEF+GFS+ +D P
Sbjct: 690 ----------KTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP 737
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 663 bits (1637), Expect = 0.0
Identities = 340/658 (51%), Positives = 418/658 (63%), Gaps = 61/658 (9%)
Query: 23 VDLEPQGKLHLKIDLKWHSQXXXXXXXXXXXXXXXXXXXXXAPREFKEXXXXXXXXXXXX 82
+DLEP+G++++ IDL S R F+E
Sbjct: 117 IDLEPEGRVYVIIDLSGSS---------------GEAPKDNEERVFRERMRPRKRQGAVR 161
Query: 83 XXVHQVNGHKFMATFLRQPTFCSLCREFIWG-IGKQGYQCQVCTCVLHKRCHSLIVTKCP 141
VHQVNGHKFMAT+LRQPT+CS CR+FIWG IGKQGYQCQVCTCV+HKRCH LI+TKC
Sbjct: 162 RRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 221
Query: 142 GMKEEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVH 200
G+K++ VG Q FSVN+PH+F +H+YK TFCDHCGSLL+GL++QGLQC+ C MNVH
Sbjct: 222 GLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVH 281
Query: 201 KRCQKNVANNCGTNTKAMAALLNEMGISPDK-----NPRPKTFKVTSSPQLPSPPTHCVT 255
+RC+ NVA NCG + + +A +L ++G++PDK R K SPQ S +
Sbjct: 282 RRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEE 341
Query: 256 RLSHPQYLNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLKKPSLEDFT---FIK 312
S +P + G L P K
Sbjct: 342 DRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAK 401
Query: 313 VLGKGSFGKVMLAERRGTEEVFAVKVLKKDAI-----------LQDDDAECTXXXXXXXX 361
LG F + + + +V ++ KD + LQDDD +CT
Sbjct: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HP+LT L+C FQT+DRLFFVMEYV+GGDLMFQIQR+RKFDEPR+RFYAAEVT AL
Sbjct: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALM 521
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
FLH+HGVIYRDLKLDNILLD+EGHCKLADFGMCKEGI++GVTTTTFCGTPDYIAPEILQE
Sbjct: 522 FLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
EYG SVDWWALGVL+YEM+AGQPPFEADNEDDLFESILHDDVLYPVWLS++AVSILK F
Sbjct: 582 LEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAF 641
Query: 542 MTKAPSRRLGVC---GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
MTK P +RLG G IK H FF+++DW L Q+K++PPF+P++
Sbjct: 642 MTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRI------------ 689
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
K+KR+ NFD +FT+EEPVLT V +++ INQEEF+GFS+ +D P
Sbjct: 690 ----------KTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP 737
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 663 bits (1637), Expect = 0.0
Identities = 340/658 (51%), Positives = 418/658 (63%), Gaps = 61/658 (9%)
Query: 23 VDLEPQGKLHLKIDLKWHSQXXXXXXXXXXXXXXXXXXXXXAPREFKEXXXXXXXXXXXX 82
+DLEP+G++++ IDL S R F+E
Sbjct: 117 IDLEPEGRVYVIIDLSGSS---------------GEAPKDNEERVFRERMRPRKRQGAVR 161
Query: 83 XXVHQVNGHKFMATFLRQPTFCSLCREFIWG-IGKQGYQCQVCTCVLHKRCHSLIVTKCP 141
VHQVNGHKFMAT+LRQPT+CS CR+FIWG IGKQGYQCQVCTCV+HKRCH LI+TKC
Sbjct: 162 RRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 221
Query: 142 GMKEEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVH 200
G+K++ VG Q FSVN+PH+F +H+YK TFCDHCGSLL+GL++QGLQC+ C MNVH
Sbjct: 222 GLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVH 281
Query: 201 KRCQKNVANNCGTNTKAMAALLNEMGISPDK-----NPRPKTFKVTSSPQLPSPPTHCVT 255
+RC+ NVA NCG + + +A +L ++G++PDK R K SPQ S +
Sbjct: 282 RRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEE 341
Query: 256 RLSHPQYLNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLKKPSLEDFT---FIK 312
S +P + G L P K
Sbjct: 342 DRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAK 401
Query: 313 VLGKGSFGKVMLAERRGTEEVFAVKVLKKDAI-----------LQDDDAECTXXXXXXXX 361
LG F + + + +V ++ KD + LQDDD +CT
Sbjct: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HP+LT L+C FQT+DRLFFVMEYV+GGDLMFQIQR+RKFDEPR+RFYAAEVT AL
Sbjct: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALM 521
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
FLH+HGVIYRDLKLDNILLD+EGHCKLADFGMCKEGI++GVTTTTFCGTPDYIAPEILQE
Sbjct: 522 FLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
EYG SVDWWALGVL+YEM+AGQPPFEADNEDDLFESILHDDVLYPVWLS++AVSILK F
Sbjct: 582 LEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAF 641
Query: 542 MTKAPSRRLGVC---GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
MTK P +RLG G IK H FF+++DW L Q+K++PPF+P++
Sbjct: 642 MTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRI------------ 689
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
K+KR+ NFD +FT+EEPVLT V +++ INQEEF+GFS+ +D P
Sbjct: 690 ----------KTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP 737
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 510 bits (1257), Expect = e-144
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 510 bits (1257), Expect = e-144
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 510 bits (1257), Expect = e-144
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 510 bits (1257), Expect = e-144
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 510 bits (1257), Expect = e-144
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 509 bits (1256), Expect = e-143
Identities = 256/570 (44%), Positives = 332/570 (58%), Gaps = 28/570 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARLPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW+ GVLLYEML
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEML 573
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVCGGAAGIKA 561
GQ PF +E++LF SI D+ YP WL ++A +L + P +RLGV G I+
Sbjct: 574 IGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG---DIRQ 630
Query: 562 HAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEF 621
H FR+++W+ L ++++ PPFRPKV KS + NFD EF
Sbjct: 631 HPLFREINWEELERKEIDPPFRPKV----------------------KSPFDCSNFDKEF 668
Query: 622 TKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
E+P L+ ++ +++Q FR FSF+N
Sbjct: 669 LNEKPRLSFADRALINSMDQNMFRNFSFMN 698
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 450 bits (1108), Expect = e-126
Identities = 215/354 (60%), Positives = 256/354 (72%), Gaps = 24/354 (6%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
+++F FI+VLGKGSFGKVMLA + T +++AVKVLKKD ILQDDD ECT
Sbjct: 352 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPFLT L C FQT DRLFFVME+V+GGDLMF IQ++R+FDE RARFYAAE+ AL FLH
Sbjct: 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 471
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+ G+IYRDLKLDN+LLD EGHCKLADFGMCKEGI +GVTT TFCGTPDYIAPEILQE Y
Sbjct: 472 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 531
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
G +VDWWA+GVLLYEML G PFEA+NEDDLFE+IL+D+V+YP WL DA ILK FMTK
Sbjct: 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 591
Query: 545 APSRRLG--VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQ 602
P+ RLG GG I H FF+++DW L R++ PPFRP++
Sbjct: 592 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRI---------------- 635
Query: 603 LCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
KS+ + NFD +F KEEPVLTP+ L INQ+EFR FS+V+ + P
Sbjct: 636 ------KSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP 683
Score = 218 bits (532), Expect = 6e-56
Identities = 93/148 (62%), Positives = 112/148 (75%), Gaps = 3/148 (2%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGI-GKQGYQCQVCTCVLHKRCHSLIVTKCPGM 143
VHQ+NGHKFMAT+LRQPT+CS CREFIWG+ GKQGYQCQVCTCV+HKRCH LIVT C
Sbjct: 166 VHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQ 225
Query: 144 KE--EAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHK 201
+ + Q F +N+PH+F +H+YK TFCDHCGSLL+G+++QGLQC+ C MNVH
Sbjct: 226 NNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHI 285
Query: 202 RCQKNVANNCGTNTKAMAALLNEMGISP 229
RCQ NVA NCG N +A L MG+ P
Sbjct: 286 RCQANVAPNCGVNAVELAKTLAGMGLQP 313
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 447 bits (1101), Expect = e-125
Identities = 214/354 (60%), Positives = 255/354 (72%), Gaps = 24/354 (6%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
+++F FI+VLGKGSFGKVMLA + T +++AVKVLKKD IL DDD ECT
Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR 410
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPFLT L C FQT DRLFFVME+V+GGDLMF IQ++R+FDE RARFYAAE+ AL FLH
Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 470
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+ G+IYRDLKLDN+LLD EGHCKLADFGMCKEGI +GVTT TFCGTPDYIAPEILQE Y
Sbjct: 471 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 530
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
G +VDWWA+GVLLYEML G PFEA+NEDDLFE+IL+D+V+YP WL DA ILK FMTK
Sbjct: 531 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 590
Query: 545 APSRRLG--VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQ 602
P+ RLG GG I H FF+++DW L R++ PPFRP++
Sbjct: 591 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRI---------------- 634
Query: 603 LCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
KS+ + NFD +F KEEPVLTP+ L INQ+EFR FS+V+ + P
Sbjct: 635 ------KSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP 682
Score = 218 bits (532), Expect = 6e-56
Identities = 93/148 (62%), Positives = 112/148 (75%), Gaps = 3/148 (2%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGI-GKQGYQCQVCTCVLHKRCHSLIVTKCPGM 143
VHQ+NGHKFMAT+LRQPT+CS CREFIWG+ GKQGYQCQVCTCV+HKRCH LIVT C
Sbjct: 165 VHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQ 224
Query: 144 KE--EAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHK 201
+ + Q F +N+PH+F +H+YK TFCDHCGSLL+G+++QGLQC+ C MNVH
Sbjct: 225 NNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHI 284
Query: 202 RCQKNVANNCGTNTKAMAALLNEMGISP 229
RCQ NVA NCG N +A L MG+ P
Sbjct: 285 RCQANVAPNCGVNAVELAKTLAGMGLQP 312
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 426 bits (1049), Expect = e-118
Identities = 205/357 (57%), Positives = 259/357 (72%), Gaps = 26/357 (7%)
Query: 300 LKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXX 359
L + L DF F+ VLGKGSFGKVMLA+R+GTEE++A+K+LKKD ++QDDD ECT
Sbjct: 331 LDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 390
Query: 360 XXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ KF EP+A FYAAE+++
Sbjct: 391 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIG 450
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH+ G+IYRDLKLDN++LDSEGH K+ADFGMCKE ++DGVTT TFCGTPDYIAPEI+
Sbjct: 451 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWWA GVLLYEMLAGQPPF+ ++ED+LF+SI+ +V YP LS++AVS+ K
Sbjct: 511 AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCK 570
Query: 540 GFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
G MTK P++RLG CG G ++ HAFFR +DW+ L R+++PPF+PKVR G+G
Sbjct: 571 GLMTKHPAKRLG-CGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVR---GKG---- 622
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
A NFD FT+ +PVLTP V+ I+Q ++ GFS+VN F
Sbjct: 623 ----------------AENFDKFFTRGQPVLTPPDQLVIANIDQSDYEGFSYVNPQF 663
Score = 167 bits (406), Expect = 1e-40
Identities = 70/128 (54%), Positives = 86/128 (67%), Gaps = 6/128 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V GHKF+A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKGHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGAD 90
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
+ H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHK+C
Sbjct: 91 KGPDTD------DPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCV 144
Query: 205 KNVANNCG 212
NV + CG
Sbjct: 145 INVPSLCG 152
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 425 bits (1048), Expect = e-118
Identities = 206/357 (57%), Positives = 258/357 (72%), Gaps = 26/357 (7%)
Query: 300 LKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXX 359
L + L DF F+ VLGKGSFGKVMLA+R+GTEE++A+K+LKKD ++QDDD ECT
Sbjct: 331 LDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 390
Query: 360 XXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ KF EP+A FYAAE+++
Sbjct: 391 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIG 450
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH+ G+IYRDLKLDN++LDSEGH K+ADFGMCKE ++DGVTT TFCGTPDYIAPEI+
Sbjct: 451 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWWA GVLLYEMLAGQPPF+ ++ED+LF+SI+ +V YP LS++AVSI K
Sbjct: 511 AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICK 570
Query: 540 GFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
G MTK P++RLG CG G ++ HAFFR +DW+ L R+++PPF+PK V G+G
Sbjct: 571 GLMTKHPAKRLG-CGPEGERDVREHAFFRRIDWEKLENREIQPPFKPK---VCGKG---- 622
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
A NFD FT+ +PVLTP V+ I+Q +F GFS+VN F
Sbjct: 623 ----------------AENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQF 663
Score = 164 bits (399), Expect = 8e-40
Identities = 69/128 (53%), Positives = 85/128 (66%), Gaps = 6/128 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF+A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGAD 90
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
+ H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHK+C
Sbjct: 91 KGPDTD------DPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCV 144
Query: 205 KNVANNCG 212
NV + CG
Sbjct: 145 INVPSLCG 152
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 425 bits (1048), Expect = e-118
Identities = 206/357 (57%), Positives = 258/357 (72%), Gaps = 26/357 (7%)
Query: 300 LKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXX 359
L + L DF F+ VLGKGSFGKVMLA+R+GTEE++A+K+LKKD ++QDDD ECT
Sbjct: 331 LDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 390
Query: 360 XXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ KF EP+A FYAAE+++
Sbjct: 391 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIG 450
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH+ G+IYRDLKLDN++LDSEGH K+ADFGMCKE ++DGVTT TFCGTPDYIAPEI+
Sbjct: 451 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWWA GVLLYEMLAGQPPF+ ++ED+LF+SI+ +V YP LS++AVSI K
Sbjct: 511 AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICK 570
Query: 540 GFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
G MTK P++RLG CG G ++ HAFFR +DW+ L R+++PPF+PK V G+G
Sbjct: 571 GLMTKHPAKRLG-CGPEGERDVREHAFFRRIDWEKLENREIQPPFKPK---VCGKG---- 622
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
A NFD FT+ +PVLTP V+ I+Q +F GFS+VN F
Sbjct: 623 ----------------AENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQF 663
Score = 164 bits (399), Expect = 8e-40
Identities = 69/128 (53%), Positives = 85/128 (66%), Gaps = 6/128 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF+A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGAD 90
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
+ H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHK+C
Sbjct: 91 KGPDTD------DPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCV 144
Query: 205 KNVANNCG 212
NV + CG
Sbjct: 145 INVPSLCG 152
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 425 bits (1048), Expect = e-118
Identities = 206/357 (57%), Positives = 258/357 (72%), Gaps = 26/357 (7%)
Query: 300 LKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXX 359
L + L DF F+ VLGKGSFGKVMLA+R+GTEE++A+K+LKKD ++QDDD ECT
Sbjct: 331 LDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 390
Query: 360 XXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ KF EP+A FYAAE+++
Sbjct: 391 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIG 450
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH+ G+IYRDLKLDN++LDSEGH K+ADFGMCKE ++DGVTT TFCGTPDYIAPEI+
Sbjct: 451 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWWA GVLLYEMLAGQPPF+ ++ED+LF+SI+ +V YP LS++AVSI K
Sbjct: 511 AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICK 570
Query: 540 GFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
G MTK P++RLG CG G ++ HAFFR +DW+ L R+++PPF+PK V G+G
Sbjct: 571 GLMTKHPAKRLG-CGPEGERDVREHAFFRRIDWEKLENREIQPPFKPK---VCGKG---- 622
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
A NFD FT+ +PVLTP V+ I+Q +F GFS+VN F
Sbjct: 623 ----------------AENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQF 663
Score = 164 bits (399), Expect = 8e-40
Identities = 69/128 (53%), Positives = 85/128 (66%), Gaps = 6/128 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF+A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGAD 90
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
+ H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHK+C
Sbjct: 91 KGPDTD------DPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCV 144
Query: 205 KNVANNCG 212
NV + CG
Sbjct: 145 INVPSLCG 152
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 421 bits (1037), Expect = e-117
Identities = 205/359 (57%), Positives = 252/359 (70%), Gaps = 26/359 (7%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 332 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 391
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 392 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 451
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 452 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 511
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 512 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 571
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK
Sbjct: 572 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA--------- 621
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
C R A NFD FT+ PVLTP +V+R I+Q EF GFSFVN +F
Sbjct: 622 -----C---------GRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEF 666
Score = 171 bits (415), Expect = 9e-42
Identities = 73/130 (56%), Positives = 87/130 (66%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPG-- 88
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
A G H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHKRC
Sbjct: 89 --ADKGPASD--DPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
Query: 205 KNVANNCGTN 214
NV + CGT+
Sbjct: 145 MNVPSLCGTD 154
Score = 59.7 bits (138), Expect = 3e-08
Identities = 24/59 (40%), Positives = 33/59 (55%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAA 220
H+F +K+ TFC HC ++G KQG QC+ C VHKRC + V +C K A+
Sbjct: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPAS 95
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 421 bits (1037), Expect = e-117
Identities = 205/359 (57%), Positives = 252/359 (70%), Gaps = 26/359 (7%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 332 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 391
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 392 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 451
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 452 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 511
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 512 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 571
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK
Sbjct: 572 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA--------- 621
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
C R A NFD FT+ PVLTP +V+R I+Q EF GFSFVN +F
Sbjct: 622 -----C---------GRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEF 666
Score = 171 bits (415), Expect = 9e-42
Identities = 73/130 (56%), Positives = 87/130 (66%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPG-- 88
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
A G H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHKRC
Sbjct: 89 --ADKGPASD--DPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
Query: 205 KNVANNCGTN 214
NV + CGT+
Sbjct: 145 MNVPSLCGTD 154
Score = 59.7 bits (138), Expect = 3e-08
Identities = 24/59 (40%), Positives = 33/59 (55%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAA 220
H+F +K+ TFC HC ++G KQG QC+ C VHKRC + V +C K A+
Sbjct: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPAS 95
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 421 bits (1037), Expect = e-117
Identities = 205/359 (57%), Positives = 252/359 (70%), Gaps = 26/359 (7%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 332 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 391
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 392 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 451
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 452 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 511
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 512 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 571
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK
Sbjct: 572 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA--------- 621
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
C R A NFD FT+ PVLTP +V+R I+Q EF GFSFVN +F
Sbjct: 622 -----C---------GRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEF 666
Score = 171 bits (415), Expect = 9e-42
Identities = 73/130 (56%), Positives = 87/130 (66%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPG-- 88
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
A G H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHKRC
Sbjct: 89 --ADKGPASD--DPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
Query: 205 KNVANNCGTN 214
NV + CGT+
Sbjct: 145 MNVPSLCGTD 154
Score = 59.7 bits (138), Expect = 3e-08
Identities = 24/59 (40%), Positives = 33/59 (55%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAA 220
H+F +K+ TFC HC ++G KQG QC+ C VHKRC + V +C K A+
Sbjct: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPAS 95
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 421 bits (1037), Expect = e-117
Identities = 205/359 (57%), Positives = 252/359 (70%), Gaps = 26/359 (7%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 155 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 214
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 215 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 274
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 275 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 334
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 335 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 394
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK
Sbjct: 395 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA--------- 444
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
C R A NFD FT+ PVLTP +V+R I+Q EF GFSFVN +F
Sbjct: 445 -----C---------GRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEF 489
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 413 bits (1018), Expect = e-115
Identities = 199/359 (55%), Positives = 249/359 (69%), Gaps = 25/359 (6%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 332 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 391
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 392 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 451
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 452 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 511
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 512 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 571
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK R
Sbjct: 572 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKAR-------- 622
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
KR+ NFD EFT++ LTP + ++Q EF GFS+ N +F
Sbjct: 623 --------------DKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEF 667
Score = 171 bits (415), Expect = 9e-42
Identities = 73/130 (56%), Positives = 87/130 (66%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWG GKQG+QCQVC V+HKRCH + CPG
Sbjct: 31 VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPG-- 88
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
A G H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHKRC
Sbjct: 89 --ADKGPASD--DPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
Query: 205 KNVANNCGTN 214
NV + CGT+
Sbjct: 145 MNVPSLCGTD 154
Score = 59.7 bits (138), Expect = 3e-08
Identities = 24/59 (40%), Positives = 33/59 (55%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAA 220
H+F +K+ TFC HC ++G KQG QC+ C VHKRC + V +C K A+
Sbjct: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPAS 95
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 413 bits (1018), Expect = e-115
Identities = 199/359 (55%), Positives = 249/359 (69%), Gaps = 25/359 (6%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXX 357
G + L DF F+ VLGKGSFGKVML+ER+GT+E++AVK+LKKD ++QDDD ECT
Sbjct: 155 GNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEK 214
Query: 358 XXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVT 417
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ +F EP A FYAAE+
Sbjct: 215 RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIA 274
Query: 418 LALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPE 477
+ L FL G+IYRDLKLDN++LDSEGH K+ADFGMCKE I DGVTT TFCGTPDYIAPE
Sbjct: 275 IGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE 334
Query: 478 ILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSI 537
I+ Q YG SVDWWA GVLLYEMLAGQ PFE ++ED+LF+SI+ +V YP +S++AV+I
Sbjct: 335 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 394
Query: 538 LKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
KG MTK P +RLG CG G IK HAFFR +DW+ L +++++PP++PK R
Sbjct: 395 CKGLMTKHPGKRLG-CGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKAR-------- 445
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
KR+ NFD EFT++ LTP + ++Q EF GFS+ N +F
Sbjct: 446 --------------DKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEF 490
>AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein.
Length = 258
Score = 409 bits (1006), Expect = e-113
Identities = 194/280 (69%), Positives = 225/280 (80%), Gaps = 25/280 (8%)
Query: 380 DRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNIL 439
DRLFFVMEYV+GGDLMFQIQR+RKFDEPR+RFYAAEVT AL FLH+HGVIYRDLKLDNIL
Sbjct: 1 DRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNIL 60
Query: 440 LDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYE 499
LD+EGHCKLADFGMCKEGI++GVTTTTFCGTPDYIAPEILQE EYG SVDWWALGVL+YE
Sbjct: 61 LDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYE 120
Query: 500 MLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLGVC---GGA 556
M+AGQPPFEADNEDDLFESILHDDVLYPVWLS++AVSILK FMTK P +RLG G
Sbjct: 121 MMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGE 180
Query: 557 AGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSKREAVN 616
IK H FF+++DW L Q+K++PPF+P++ K+KR+ N
Sbjct: 181 DAIKQHPFFKEIDWVLLEQKKIKPPFKPRI----------------------KTKRDVNN 218
Query: 617 FDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNP 656
FD +FT+EEPVLT V +++ INQEEF+GFS+ +D P
Sbjct: 219 FDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP 258
>Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma
protein.
Length = 536
Score = 394 bits (970), Expect = e-109
Identities = 193/356 (54%), Positives = 244/356 (68%), Gaps = 29/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
+ DF+F+ VLGKGSFGKVMLAERRG++E++A+K+LKKD I+QDDD +CT
Sbjct: 187 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 246
Query: 365 XHP-----FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
P FLT LH FQT DRL+FVMEYV GGDLM+ IQ+ KF EP A FYAAE+ +
Sbjct: 247 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 306
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH G+IYRDLKLDN++LD+EGH K+ DFGMCKE + G TT TFCGTPDYIAPEI+
Sbjct: 307 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 366
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWW+ GVLLYEMLAGQPPF+ ++E++LF++I+ V YP LSR+AV+I K
Sbjct: 367 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 426
Query: 540 GFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
GF+TK P +RLG G I+AH FFR +DW+ L + ++ PPFRP+ +GE
Sbjct: 427 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE------ 480
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
NFD FT+ P LTP VL +I+Q +F+GF++VN DF
Sbjct: 481 -----------------NFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDF 519
>BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma
protein.
Length = 697
Score = 394 bits (970), Expect = e-109
Identities = 193/356 (54%), Positives = 244/356 (68%), Gaps = 29/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
+ DF+F+ VLGKGSFGKVMLAERRG++E++A+K+LKKD I+QDDD +CT
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 407
Query: 365 XHP-----FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
P FLT LH FQT DRL+FVMEYV GGDLM+ IQ+ KF EP A FYAAE+ +
Sbjct: 408 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH G+IYRDLKLDN++LD+EGH K+ DFGMCKE + G TT TFCGTPDYIAPEI+
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWW+ GVLLYEMLAGQPPF+ ++E++LF++I+ V YP LSR+AV+I K
Sbjct: 528 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 587
Query: 540 GFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
GF+TK P +RLG G I+AH FFR +DW+ L + ++ PPFRP+ +GE
Sbjct: 588 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE------ 641
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
NFD FT+ P LTP VL +I+Q +F+GF++VN DF
Sbjct: 642 -----------------NFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDF 680
Score = 168 bits (409), Expect = 5e-41
Identities = 72/130 (55%), Positives = 90/130 (69%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWGIGKQG QCQVC+ V+H+RCH + +CPG
Sbjct: 30 VHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPG-- 87
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
AG G Q H+F +HSY TFCDHCGSLLYGL+ QG++C C MNVH+RC
Sbjct: 88 --AGKGP--QTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCV 143
Query: 205 KNVANNCGTN 214
++V + CG +
Sbjct: 144 RSVPSLCGVD 153
>AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma
protein.
Length = 697
Score = 394 bits (970), Expect = e-109
Identities = 193/356 (54%), Positives = 244/356 (68%), Gaps = 29/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
+ DF+F+ VLGKGSFGKVMLAERRG++E++A+K+LKKD I+QDDD +CT
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 407
Query: 365 XHP-----FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
P FLT LH FQT DRL+FVMEYV GGDLM+ IQ+ KF EP A FYAAE+ +
Sbjct: 408 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH G+IYRDLKLDN++LD+EGH K+ DFGMCKE + G TT TFCGTPDYIAPEI+
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILK 539
Q YG SVDWW+ GVLLYEMLAGQPPF+ ++E++LF++I+ V YP LSR+AV+I K
Sbjct: 528 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 587
Query: 540 GFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
GF+TK P +RLG G I+AH FFR +DW+ L + ++ PPFRP+ +GE
Sbjct: 588 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE------ 641
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDF 654
NFD FT+ P LTP VL +I+Q +F+GF++VN DF
Sbjct: 642 -----------------NFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDF 680
Score = 168 bits (409), Expect = 5e-41
Identities = 72/130 (55%), Positives = 90/130 (69%), Gaps = 6/130 (4%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH+V HKF A F +QPTFCS C +FIWGIGKQG QCQVC+ V+H+RCH + +CPG
Sbjct: 30 VHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPG-- 87
Query: 145 EEAGAGAVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQ 204
AG G Q H+F +HSY TFCDHCGSLLYGL+ QG++C C MNVH+RC
Sbjct: 88 --AGKGP--QTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCV 143
Query: 205 KNVANNCGTN 214
++V + CG +
Sbjct: 144 RSVPSLCGVD 153
>AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta
protein.
Length = 643
Score = 386 bits (951), Expect = e-106
Identities = 187/397 (47%), Positives = 235/397 (59%), Gaps = 3/397 (0%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
VH V H+F ATF QPTFCS+C EF+WG+ KQGYQC+ C +HK+C ++ KC G
Sbjct: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F +++PHRF V++YK TFC+HCG+LL+GL +QGL+C+AC MNVH RC
Sbjct: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273
Query: 204 QKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTHCVTRLSHPQY 262
Q VAN CG N K MA L + + T ++ P P P
Sbjct: 274 QTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARLPCL 333
Query: 263 LNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFIKVLGKGSFGK 321
P E L+ K +EDF K+LGKGSFGK
Sbjct: 334 PTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGK 393
Query: 322 VMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALHCAFQTRDR 381
V LAE + T + FA+K LKKD +L DDD ECT HPFLT + C FQT++
Sbjct: 394 VFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKEN 453
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YRDLKLDNILLD
Sbjct: 454 LFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD 513
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
+GH K+ADFGMCKE ++ T TFCGTPDYIAPE+
Sbjct: 514 KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEL 550
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 25/108 (23%)
Query: 544 KAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
+ P +RLGV G I+ H FR+++W+ L ++++ PPFRPKV
Sbjct: 553 REPEKRLGVRGD---IRQHPLFREINWEELERKEIDPPFRPKV----------------- 592
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
KS + NFD EF E+P L+ ++ +++Q FR FSF+N
Sbjct: 593 -----KSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMN 635
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 377 bits (928), Expect = e-104
Identities = 202/460 (43%), Positives = 256/460 (55%), Gaps = 27/460 (5%)
Query: 194 ACSMNVHKRCQKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTH 252
AC MNVH RCQ VAN CG N K MA L + + T ++ P P
Sbjct: 36 ACGMNVHHRCQTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCS 95
Query: 253 CVTRLSHPQYLNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFI 311
P P E L+ K +EDF
Sbjct: 96 IKNEARPPCLPTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILH 155
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K+LGKGSFGKV LAE + T + FA+K LKKD +L DDD ECT HPFLT
Sbjct: 156 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 215
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
+ C FQT++ LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YR
Sbjct: 216 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 275
Query: 432 DLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWW 491
DLKLDNILLD +GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW
Sbjct: 276 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWW 335
Query: 492 ALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLG 551
+ GVLLYEML GQ PF +E++LF SI D+ YP WL ++A +L + P +RLG
Sbjct: 336 SFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG 395
Query: 552 VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSK 611
V G I+ H FR+++W+ L ++++ PPFRPKV KS
Sbjct: 396 VRG---DIRQHPLFREINWEELERKEIDPPFRPKV----------------------KSP 430
Query: 612 REAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
+ NFD EF E+P L+ ++ +++Q FR FSF+N
Sbjct: 431 FDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMN 470
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 377 bits (928), Expect = e-104
Identities = 202/460 (43%), Positives = 256/460 (55%), Gaps = 27/460 (5%)
Query: 194 ACSMNVHKRCQKNVANNCGTNTKAMAALLNEMGISPDKNPRPKTFKV-TSSPQLPSPPTH 252
AC MNVH RCQ VAN CG N K MA L + + T ++ P P
Sbjct: 36 ACGMNVHHRCQTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCS 95
Query: 253 CVTRLSHPQYLNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTECGGLK-KPSLEDFTFI 311
P P E L+ K +EDF
Sbjct: 96 IKNEARPPCLPTPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILH 155
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K+LGKGSFGKV LAE + T + FA+K LKKD +L DDD ECT HPFLT
Sbjct: 156 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 215
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
+ C FQT++ LFFVMEY++GGDLM+ IQ KFD RA FYAAE+ L L+FLH G++YR
Sbjct: 216 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 275
Query: 432 DLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWW 491
DLKLDNILLD +GH K+ADFGMCKE ++ T TFCGTPDYIAPEIL Q+Y SVDWW
Sbjct: 276 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWW 335
Query: 492 ALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLG 551
+ GVLLYEML GQ PF +E++LF SI D+ YP WL ++A +L + P +RLG
Sbjct: 336 SFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG 395
Query: 552 VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLCFRLQKSK 611
V G I+ H FR+++W+ L ++++ PPFRPKV KS
Sbjct: 396 VRG---DIRQHPLFREINWEELERKEIDPPFRPKV----------------------KSP 430
Query: 612 REAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
+ NFD EF E+P L+ ++ +++Q FR FSF+N
Sbjct: 431 FDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMN 470
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 363 bits (893), Expect = 1e-99
Identities = 182/359 (50%), Positives = 231/359 (64%), Gaps = 25/359 (6%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXX 358
G K ++ +F F KVLGKGSFGKV+L E +G E FA+K LKKD +L DDD ECT
Sbjct: 340 GSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKR 399
Query: 359 XXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
+PFLT L C FQT+D LFFVME+++GGDLM+ IQ +F+ RA FYAAE+
Sbjct: 400 VLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMC 459
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLH G+IYRDLKLDN+LLD +GH K+ADFGMCKE I +TFCGTPDYIAPEI
Sbjct: 460 GLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEI 519
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
LQ +Y SVDWW+ GVLLYEML GQ PF D+ED+LFESI D YP W+++++ IL
Sbjct: 520 LQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIL 579
Query: 539 KGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
+ + P++RLGV G IK H FF+ ++W L +R+L PPFRPKV
Sbjct: 580 EKLFEREPTKRLGVTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKV------------ 624
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNPL 657
KS R+ NFD EF E+ L+ +++ +++Q F GFSFVN F L
Sbjct: 625 ----------KSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHL 673
Score = 178 bits (434), Expect = 4e-44
Identities = 70/142 (49%), Positives = 101/142 (71%), Gaps = 1/142 (0%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
+H + H+F+ATF QPTFCS+C++F+WG+ KQGY+C+ C +HK+C I+ +C G
Sbjct: 153 IHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTA 212
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F++++PHRF VH+Y TFCDHCGSLL+GL+KQGL+CE C MNVH +C
Sbjct: 213 ANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKC 272
Query: 204 QKNVANNCGTNTKAMAALLNEM 225
++ VAN CG N K +A LN++
Sbjct: 273 REKVANLCGINQKLLAEALNQV 294
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 363 bits (893), Expect = 1e-99
Identities = 182/359 (50%), Positives = 231/359 (64%), Gaps = 25/359 (6%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXX 358
G K ++ +F F KVLGKGSFGKV+L E +G E FA+K LKKD +L DDD ECT
Sbjct: 290 GSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKR 349
Query: 359 XXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
+PFLT L C FQT+D LFFVME+++GGDLM+ IQ +F+ RA FYAAE+
Sbjct: 350 VLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMC 409
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLH G+IYRDLKLDN+LLD +GH K+ADFGMCKE I +TFCGTPDYIAPEI
Sbjct: 410 GLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEI 469
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
LQ +Y SVDWW+ GVLLYEML GQ PF D+ED+LFESI D YP W+++++ IL
Sbjct: 470 LQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIL 529
Query: 539 KGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
+ + P++RLGV G IK H FF+ ++W L +R+L PPFRPKV
Sbjct: 530 EKLFEREPTKRLGVTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKV------------ 574
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNPL 657
KS R+ NFD EF E+ L+ +++ +++Q F GFSFVN F L
Sbjct: 575 ----------KSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHL 623
Score = 178 bits (434), Expect = 4e-44
Identities = 70/142 (49%), Positives = 101/142 (71%), Gaps = 1/142 (0%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
+H + H+F+ATF QPTFCS+C++F+WG+ KQGY+C+ C +HK+C I+ +C G
Sbjct: 103 IHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTA 162
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F++++PHRF VH+Y TFCDHCGSLL+GL+KQGL+CE C MNVH +C
Sbjct: 163 ANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKC 222
Query: 204 QKNVANNCGTNTKAMAALLNEM 225
++ VAN CG N K +A LN++
Sbjct: 223 REKVANLCGINQKLLAEALNQV 244
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 363 bits (893), Expect = 1e-99
Identities = 182/359 (50%), Positives = 231/359 (64%), Gaps = 25/359 (6%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXX 358
G K ++ +F F KVLGKGSFGKV+L E +G E FA+K LKKD +L DDD ECT
Sbjct: 340 GSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKR 399
Query: 359 XXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
+PFLT L C FQT+D LFFVME+++GGDLM+ IQ +F+ RA FYAAE+
Sbjct: 400 VLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMC 459
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLH G+IYRDLKLDN+LLD +GH K+ADFGMCKE I +TFCGTPDYIAPEI
Sbjct: 460 GLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEI 519
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
LQ +Y SVDWW+ GVLLYEML GQ PF D+ED+LFESI D YP W+++++ IL
Sbjct: 520 LQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIL 579
Query: 539 KGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
+ + P++RLGV G IK H FF+ ++W L +R+L PPFRPKV
Sbjct: 580 EKLFEREPTKRLGVTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKV------------ 624
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNPL 657
KS R+ NFD EF E+ L+ +++ +++Q F GFSFVN F L
Sbjct: 625 ----------KSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHL 673
Score = 178 bits (434), Expect = 4e-44
Identities = 70/142 (49%), Positives = 101/142 (71%), Gaps = 1/142 (0%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
+H + H+F+ATF QPTFCS+C++F+WG+ KQGY+C+ C +HK+C I+ +C G
Sbjct: 153 IHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTA 212
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F++++PHRF VH+Y TFCDHCGSLL+GL+KQGL+CE C MNVH +C
Sbjct: 213 ANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKC 272
Query: 204 QKNVANNCGTNTKAMAALLNEM 225
++ VAN CG N K +A LN++
Sbjct: 273 REKVANLCGINQKLLAEALNQV 294
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 359 bits (882), Expect = 2e-98
Identities = 180/359 (50%), Positives = 230/359 (64%), Gaps = 25/359 (6%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXX 358
G K ++ +F F KVLGKGSFGKV+L E +G E A+K LKKD +L DDD ECT
Sbjct: 340 GSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKR 399
Query: 359 XXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
+PFLT L C FQT+D LFFVME+++GGDLM+ IQ +F+ RA FYAAE+
Sbjct: 400 VLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMC 459
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLH G+IYRDLKLDN+LLD +GH K+ADFGMCKE I +TFCGTPDYIAPEI
Sbjct: 460 GLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEI 519
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
LQ +Y SVDWW+ GVLLYEML GQ PF D+ED+LFESI D YP W+++++ IL
Sbjct: 520 LQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIL 579
Query: 539 KGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEG 598
+ + P++RLG+ G IK H FF+ ++W L +R+L PPFRPKV
Sbjct: 580 EKLFEREPTKRLGMTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKV------------ 624
Query: 599 ALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVNKDFNPL 657
KS R+ NFD EF E+ L+ +++ +++Q F GFSFVN F L
Sbjct: 625 ----------KSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHL 673
Score = 178 bits (434), Expect = 4e-44
Identities = 70/142 (49%), Positives = 101/142 (71%), Gaps = 1/142 (0%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMK 144
+H + H+F+ATF QPTFCS+C++F+WG+ KQGY+C+ C +HK+C I+ +C G
Sbjct: 153 IHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTA 212
Query: 145 EEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
+ + F++++PHRF VH+Y TFCDHCGSLL+GL+KQGL+CE C MNVH +C
Sbjct: 213 ANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKC 272
Query: 204 QKNVANNCGTNTKAMAALLNEM 225
++ VAN CG N K +A LN++
Sbjct: 273 REKVANLCGINQKLLAEALNQV 294
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 352 bits (866), Expect = 2e-96
Identities = 176/358 (49%), Positives = 236/358 (65%), Gaps = 33/358 (9%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF ++V+G+GS+ KV+L + T+ ++A+KV+KK+ + D+D +
Sbjct: 242 LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQAS 301
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPFL LH FQT RLFFV+EYV+GGDLMF +QR RK E ARFY+AE++LAL +LH
Sbjct: 302 NHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLH 361
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLDSEGH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ ++Y
Sbjct: 362 ERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDY 421
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE----ADN-----EDDLFESILHDDVLYPVWLSRDAV 535
G SVDWWALGVL++EM+AG+ PF+ +DN ED LF+ IL + P +S A
Sbjct: 422 GFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSMSVKAA 481
Query: 536 SILKGFMTKAPSRRLGVC--GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEG 593
S+LK F+ K P RLG G A I+ H FFR+VDWD + Q+++ PPF+P ++GE
Sbjct: 482 SVLKSFLNKDPKERLGCLPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP---NISGE- 537
Query: 594 SVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
F L NFD++FT E LTP D++R I+Q EF GF ++N
Sbjct: 538 -----------FGLD-------NFDSQFTNERVQLTPDDDDIVRKIDQSEFEGFEYIN 577
Score = 65.3 bits (152), Expect = 7e-10
Identities = 22/52 (42%), Positives = 34/52 (65%)
Query: 89 NGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
NGH F A + C++C + IWG+G+QGY+C C ++HK+CH L+ +C
Sbjct: 130 NGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIEC 181
Score = 46.0 bits (104), Expect = 4e-04
Identities = 19/54 (35%), Positives = 28/54 (51%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNT 215
H F + R C C ++GL +QG +C C + VHK+C K V CG ++
Sbjct: 132 HTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHS 185
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 352 bits (865), Expect = 3e-96
Identities = 177/358 (49%), Positives = 236/358 (65%), Gaps = 33/358 (9%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF ++V+G+GS+ KV+L + T+ ++A+KV+KK+ + D+D +
Sbjct: 242 LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQAS 301
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPFL LH FQT RLFFV+EYV+GGDLMF +QR RK E ARFY+AE++LAL +LH
Sbjct: 302 NHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLH 361
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLDSEGH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ ++Y
Sbjct: 362 ERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDY 421
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE----ADN-----EDDLFESILHDDVLYPVWLSRDAV 535
G SVDWWALGVL++EM+AG+ PF+ +DN ED LF+ IL + P LS A
Sbjct: 422 GFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAA 481
Query: 536 SILKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEG 593
S+LK F+ K P RLG G A I+ H FFR+VDWD + Q+++ PPF+P ++GE
Sbjct: 482 SVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP---NISGE- 537
Query: 594 SVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
F L NFD++FT E LTP D++R I+Q EF GF ++N
Sbjct: 538 -----------FGLD-------NFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYIN 577
Score = 65.3 bits (152), Expect = 7e-10
Identities = 22/52 (42%), Positives = 34/52 (65%)
Query: 89 NGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
NGH F A + C++C + IWG+G+QGY+C C ++HK+CH L+ +C
Sbjct: 130 NGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIEC 181
Score = 46.0 bits (104), Expect = 4e-04
Identities = 19/54 (35%), Positives = 28/54 (51%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNT 215
H F + R C C ++GL +QG +C C + VHK+C K V CG ++
Sbjct: 132 HTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHS 185
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 352 bits (865), Expect = 3e-96
Identities = 177/358 (49%), Positives = 236/358 (65%), Gaps = 33/358 (9%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF ++V+G+GS+ KV+L + T+ ++A+KV+KK+ + D+D +
Sbjct: 242 LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQAS 301
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPFL LH FQT RLFFV+EYV+GGDLMF +QR RK E ARFY+AE++LAL +LH
Sbjct: 302 NHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLH 361
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLDSEGH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ ++Y
Sbjct: 362 ERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDY 421
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE----ADN-----EDDLFESILHDDVLYPVWLSRDAV 535
G SVDWWALGVL++EM+AG+ PF+ +DN ED LF+ IL + P LS A
Sbjct: 422 GFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAA 481
Query: 536 SILKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEG 593
S+LK F+ K P RLG G A I+ H FFR+VDWD + Q+++ PPF+P ++GE
Sbjct: 482 SVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP---NISGE- 537
Query: 594 SVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
F L NFD++FT E LTP D++R I+Q EF GF ++N
Sbjct: 538 -----------FGLD-------NFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYIN 577
Score = 65.3 bits (152), Expect = 7e-10
Identities = 22/52 (42%), Positives = 34/52 (65%)
Query: 89 NGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
NGH F A + C++C + IWG+G+QGY+C C ++HK+CH L+ +C
Sbjct: 130 NGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIEC 181
Score = 46.0 bits (104), Expect = 4e-04
Identities = 19/54 (35%), Positives = 28/54 (51%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNT 215
H F + R C C ++GL +QG +C C + VHK+C K V CG ++
Sbjct: 132 HTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHS 185
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 241 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 300
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 301 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 360
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 361 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 420
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 421 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 480
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 481 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 536
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 537 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 574
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 117 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 172
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 123 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 172
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 343 bits (842), Expect = 2e-93
Identities = 171/356 (48%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+GS+ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 341 bits (839), Expect = 4e-93
Identities = 170/356 (47%), Positives = 229/356 (64%), Gaps = 31/356 (8%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+DF I+V+G+G++ KV+L + ++++A+KV+KK+ + D+D +
Sbjct: 249 LQDFDLIRVIGRGTYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
+PFL LH FQT RLF V+EYV+GGDLMF +QR RK E ARFYAAE+ +AL FLH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
E G+IYRDLKLDN+LLD++GH KL D+GMCKEG+ G TT+TFCGTP+YIAPEIL+ +EY
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 485 GCSVDWWALGVLLYEMLAGQPPFE--ADN-----EDDLFESILHDDVLYPVWLSRDAVSI 537
G SVDWWALGVL++EM+AG+ PF+ DN ED LF+ IL + P +LS A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 538 LKGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSV 595
LKGF+ K P RLG G + IK+HAFFR +DWD L +++ PPF+P++ G
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYG---- 544
Query: 596 AEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFVN 651
NFD +FT E LTP D ++ I+Q EF GF ++N
Sbjct: 545 ------------------LDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
Score = 64.5 bits (150), Expect = 1e-09
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 85 VHQVNGHKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKC 140
+++ NGH F A + +C C E IWG+ +QGY+C C ++HKRCH L+ C
Sbjct: 125 LYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
Score = 46.0 bits (104), Expect = 4e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H F + R +C C ++GL +QG +C C + VHKRC V C
Sbjct: 131 HLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC 180
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 323 bits (793), Expect = 1e-87
Identities = 164/351 (46%), Positives = 222/351 (63%), Gaps = 27/351 (7%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKK-DAILQDD-DAECTXXXXXXXX 361
+L+DF VLG+G FGKV+LAE + T E+FA+K LKK D + +D+ D+
Sbjct: 653 NLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 712
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL L FQT++ + FVMEY GGDLM I F EPRA FYAA V L L+
Sbjct: 713 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLGLQ 771
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LHEH ++YRDLKLDN+LLD+EG K+ADFG+CKEG+ G T+TFCGTP+++APE+L E
Sbjct: 772 YLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Y +VDWW LGVL+YEML G+ PF D+E+++F+SI++D+V YP +LS +A+SI++
Sbjct: 832 TSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRL 891
Query: 542 MTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGAL 600
+ + P RRLG A +K H FFR +DW AL +K++PPF P +R
Sbjct: 892 LRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR------------- 938
Query: 601 CQLCFRLQKSKREAVNFDAEFTKEEPVLTPV-APDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P+LTP P +L QE FR F ++
Sbjct: 939 ---------GREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI 980
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 323 bits (793), Expect = 1e-87
Identities = 164/351 (46%), Positives = 222/351 (63%), Gaps = 27/351 (7%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKK-DAILQDD-DAECTXXXXXXXX 361
+L+DF VLG+G FGKV+LAE + T E+FA+K LKK D + +D+ D+
Sbjct: 653 NLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 712
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL L FQT++ + FVMEY GGDLM I F EPRA FYAA V L L+
Sbjct: 713 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLGLQ 771
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LHEH ++YRDLKLDN+LLD+EG K+ADFG+CKEG+ G T+TFCGTP+++APE+L E
Sbjct: 772 YLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Y +VDWW LGVL+YEML G+ PF D+E+++F+SI++D+V YP +LS +A+SI++
Sbjct: 832 TSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRL 891
Query: 542 MTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGAL 600
+ + P RRLG A +K H FFR +DW AL +K++PPF P +R
Sbjct: 892 LRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR------------- 938
Query: 601 CQLCFRLQKSKREAVNFDAEFTKEEPVLTPV-APDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P+LTP P +L QE FR F ++
Sbjct: 939 ---------GREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI 980
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 323 bits (793), Expect = 1e-87
Identities = 164/351 (46%), Positives = 222/351 (63%), Gaps = 27/351 (7%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKK-DAILQDD-DAECTXXXXXXXX 361
+L+DF VLG+G FGKV+LAE + T E+FA+K LKK D + +D+ D+
Sbjct: 653 NLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 712
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL L FQT++ + FVMEY GGDLM I F EPRA FYAA V L L+
Sbjct: 713 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLGLQ 771
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LHEH ++YRDLKLDN+LLD+EG K+ADFG+CKEG+ G T+TFCGTP+++APE+L E
Sbjct: 772 YLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Y +VDWW LGVL+YEML G+ PF D+E+++F+SI++D+V YP +LS +A+SI++
Sbjct: 832 TSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRL 891
Query: 542 MTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGAL 600
+ + P RRLG A +K H FFR +DW AL +K++PPF P +R
Sbjct: 892 LRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR------------- 938
Query: 601 CQLCFRLQKSKREAVNFDAEFTKEEPVLTPV-APDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P+LTP P +L QE FR F ++
Sbjct: 939 ---------GREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI 980
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 322 bits (791), Expect = 2e-87
Identities = 164/351 (46%), Positives = 222/351 (63%), Gaps = 27/351 (7%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKK-DAILQDD-DAECTXXXXXXXX 361
+L+DF VLG+G FGKV+LAE + T E+FA+K LKK D + +D+ D+
Sbjct: 605 NLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 664
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL L FQT++ + FVMEY GGDLM I F EPRA FYAA V L L+
Sbjct: 665 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLGLQ 723
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LHEH ++YRDLKLDN+LLD+EG K+ADFG+CKEG+ G T+TFCGTP+++APE+L E
Sbjct: 724 YLHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 783
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Y +VDWW LGVL+YEML G+ PF D+E+++F+SI++D+V YP +LS +A+SI++
Sbjct: 784 TSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRL 843
Query: 542 MTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGAL 600
+ + P RRLG A +K H FFR +DW AL +K++PPF P +R
Sbjct: 844 LRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR------------- 890
Query: 601 CQLCFRLQKSKREAVNFDAEFTKEEPVLTPV-APDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P+LTP P +L QE FR F ++
Sbjct: 891 ---------GREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI 932
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 311 bits (764), Expect = 5e-84
Identities = 141/288 (48%), Positives = 197/288 (68%), Gaps = 6/288 (2%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
K ++ DF ++K+LGKG+FGKV+L + T +A+K+L+K+ I+ D+ T
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFLTAL AFQT DRL FVMEY +GG+L F + R R F E RARFY AE+ ALE
Sbjct: 206 NTR-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALE 264
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH V+YRD+KL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 YLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED 324
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P LS +A S+L G
Sbjct: 325 NDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGL 384
Query: 542 MTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P +RLG GG A + H FF ++W + Q+KL PPF+P+V
Sbjct: 385 LKKDPKQRLG--GGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQV 430
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 311 bits (764), Expect = 5e-84
Identities = 141/288 (48%), Positives = 197/288 (68%), Gaps = 6/288 (2%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
K ++ DF ++K+LGKG+FGKV+L + T +A+K+L+K+ I+ D+ T
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFLTAL AFQT DRL FVMEY +GG+L F + R R F E RARFY AE+ ALE
Sbjct: 206 NTR-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALE 264
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH V+YRD+KL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 YLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED 324
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P LS +A S+L G
Sbjct: 325 NDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGL 384
Query: 542 MTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P +RLG GG A + H FF ++W + Q+KL PPF+P+V
Sbjct: 385 LKKDPKQRLG--GGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQV 430
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 311 bits (764), Expect = 5e-84
Identities = 141/288 (48%), Positives = 197/288 (68%), Gaps = 6/288 (2%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
K ++ DF ++K+LGKG+FGKV+L + T +A+K+L+K+ I+ D+ T
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFLTAL AFQT DRL FVMEY +GG+L F + R R F E RARFY AE+ ALE
Sbjct: 206 NTR-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALE 264
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH V+YRD+KL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 YLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED 324
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P LS +A S+L G
Sbjct: 325 NDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGL 384
Query: 542 MTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P +RLG GG A + H FF ++W + Q+KL PPF+P+V
Sbjct: 385 LKKDPKQRLG--GGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQV 430
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 311 bits (763), Expect = 6e-84
Identities = 140/289 (48%), Positives = 200/289 (69%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++LD +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 308 bits (757), Expect = 3e-83
Identities = 139/289 (48%), Positives = 199/289 (68%), Gaps = 6/289 (2%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K+ ++ DF ++K+LGKG+FGKV+L + + + +A+K+LKK+ I+ D+ T
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPFLT+L +FQT+DRL FVMEYV+GG+L F + R R F E R RFY AE+ AL
Sbjct: 201 KNTR-HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQ 480
++LH ++YRDLKL+N++ D +GH K+ DFG+CKEGI D T TFCGTP+Y+APE+L+
Sbjct: 260 DYLHSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLE 319
Query: 481 EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKG 540
+ +YG +VDWW LGV++YEM+ G+ PF + + LFE IL +D+ +P LS DA S+L G
Sbjct: 320 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379
Query: 541 FMTKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K P++RLG GG A I H+FF V+W + +KL PPF+P+V
Sbjct: 380 LLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV 426
>AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha
variant protein.
Length = 461
Score = 305 bits (750), Expect = 2e-82
Identities = 138/208 (66%), Positives = 164/208 (78%)
Query: 300 LKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXX 359
L + L DF F+ VLGKGSFGKVMLA+R+GTEE++A+K+LKKD ++QDDD ECT
Sbjct: 242 LDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 301
Query: 360 XXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLA 419
PFLT LH FQT DRL+FVMEYV+GGDLM+ IQ+ KF EP+A FY AE+++
Sbjct: 302 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYVAEISIG 361
Query: 420 LEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEIL 479
L FLH+ G+IYRDLKLDN++LDSEGH K+ADFGMCKE ++DGVTT TFCGTPDYIAPEI+
Sbjct: 362 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 421
Query: 480 QEQEYGCSVDWWALGVLLYEMLAGQPPF 507
Q YG SVDWWA GVLLYEMLAGQ F
Sbjct: 422 AYQPYGKSVDWWAYGVLLYEMLAGQVMF 449
Score = 83.0 bits (196), Expect = 3e-15
Identities = 32/51 (62%), Positives = 40/51 (78%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCG 212
H+F +H+Y TFCDHCGSLLYGLI QG++C+ C MNVHK+C NV + CG
Sbjct: 13 HKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCG 63
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEEAGAG 150
HKF PTFC C ++G+ QG +C C +HK+C + + C GM G
Sbjct: 13 HKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLC-GMDHTEKRG 71
Query: 151 AV 152
+
Sbjct: 72 RI 73
>U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein.
Length = 942
Score = 304 bits (746), Expect = 7e-82
Identities = 163/360 (45%), Positives = 218/360 (60%), Gaps = 29/360 (8%)
Query: 297 CGGLKKP--SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTX 354
C L+K +LEDF F+ VLG+G FGKV+L+E R + E+FA+K LKK I+ D+ E
Sbjct: 602 CSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLM 661
Query: 355 --XXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFY 412
HPFL L FQT + + FVMEY GGDLM I + F EPRA FY
Sbjct: 662 CEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFY 720
Query: 413 AAEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPD 472
+A V L L+FLHEH ++YRDLKLDN+LLD+EG+ K+ADFG+CKEG+ G T+TFCGTP+
Sbjct: 721 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 780
Query: 473 YIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSR 532
++APE+L + Y +VDWW LGVLLYEML G+ PF D+E+++F+SI++D+V YP +LS
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 533 DAVSILKGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAG 591
+A+ I++ + + P RRLG A +K FFR + W+AL R+L PPF P +
Sbjct: 841 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL----- 895
Query: 592 EGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVA-PDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P L+P L Q F F FV
Sbjct: 896 -----------------SGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFV 938
>S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein.
Length = 942
Score = 304 bits (746), Expect = 7e-82
Identities = 163/360 (45%), Positives = 218/360 (60%), Gaps = 29/360 (8%)
Query: 297 CGGLKKP--SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTX 354
C L+K +LEDF F+ VLG+G FGKV+L+E R + E+FA+K LKK I+ D+ E
Sbjct: 602 CSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLM 661
Query: 355 --XXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFY 412
HPFL L FQT + + FVMEY GGDLM I + F EPRA FY
Sbjct: 662 CEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFY 720
Query: 413 AAEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPD 472
+A V L L+FLHEH ++YRDLKLDN+LLD+EG+ K+ADFG+CKEG+ G T+TFCGTP+
Sbjct: 721 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 780
Query: 473 YIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSR 532
++APE+L + Y +VDWW LGVLLYEML G+ PF D+E+++F+SI++D+V YP +LS
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 533 DAVSILKGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAG 591
+A+ I++ + + P RRLG A +K FFR + W+AL R+L PPF P +
Sbjct: 841 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL----- 895
Query: 592 EGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVA-PDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P L+P L Q F F FV
Sbjct: 896 -----------------SGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFV 938
>D26181-1|BAA05169.1| 942|Homo sapiens PKN protein.
Length = 942
Score = 304 bits (746), Expect = 7e-82
Identities = 163/360 (45%), Positives = 218/360 (60%), Gaps = 29/360 (8%)
Query: 297 CGGLKKP--SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTX 354
C L+K +LEDF F+ VLG+G FGKV+L+E R + E+FA+K LKK I+ D+ E
Sbjct: 602 CSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLM 661
Query: 355 --XXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFY 412
HPFL L FQT + + FVMEY GGDLM I + F EPRA FY
Sbjct: 662 CEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFY 720
Query: 413 AAEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPD 472
+A V L L+FLHEH ++YRDLKLDN+LLD+EG+ K+ADFG+CKEG+ G T+TFCGTP+
Sbjct: 721 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 780
Query: 473 YIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSR 532
++APE+L + Y +VDWW LGVLLYEML G+ PF D+E+++F+SI++D+V YP +LS
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 533 DAVSILKGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAG 591
+A+ I++ + + P RRLG A +K FFR + W+AL R+L PPF P +
Sbjct: 841 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL----- 895
Query: 592 EGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVA-PDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P L+P L Q F F FV
Sbjct: 896 -----------------SGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFV 938
>BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein.
Length = 942
Score = 303 bits (745), Expect = 9e-82
Identities = 163/360 (45%), Positives = 218/360 (60%), Gaps = 29/360 (8%)
Query: 297 CGGLKKP--SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTX 354
C L+K +LEDF F+ VLG+G FGKV+L+E R + E+FA+K LKK I+ D+ E
Sbjct: 602 CSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLM 661
Query: 355 --XXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFY 412
HPFL L FQT + + FVMEY GGDLM I + F EPRA FY
Sbjct: 662 CEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFY 720
Query: 413 AAEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPD 472
+A V L L+FLHEH ++YRDLKLDN+LLD+EG+ K+ADFG+CKEG+ G T+TFCGTP+
Sbjct: 721 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 780
Query: 473 YIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSR 532
++APE+L + Y +VDWW LGVLLYEML G+ PF D+E+++F+SI++D+V YP +LS
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 533 DAVSILKGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAG 591
+A+ I++ + + P RRLG A +K FFR + W+AL R+L PPF P +
Sbjct: 841 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL----- 895
Query: 592 EGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVA-PDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P L+P L Q F F FV
Sbjct: 896 -----------------SGRTDISNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFV 938
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 301 bits (740), Expect = 4e-81
Identities = 139/287 (48%), Positives = 196/287 (68%), Gaps = 7/287 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
++ +F ++K+LGKG+FGKV+L + + T +A+K+LKK+ I+ D+ T
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFLTAL +FQT DRL FVMEY +GG+L F + R R F E RARFY AE+ AL++L
Sbjct: 206 R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYL 264
Query: 424 H-EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQ 482
H E V+YRDLKL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDN 324
Query: 483 EYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFM 542
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P L +A S+L G +
Sbjct: 325 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 384
Query: 543 TKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P +RLG GG A I H FF + W + ++KL PPF+P+V
Sbjct: 385 KKDPKQRLG--GGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV 429
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 301 bits (740), Expect = 4e-81
Identities = 139/287 (48%), Positives = 196/287 (68%), Gaps = 7/287 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
++ +F ++K+LGKG+FGKV+L + + T +A+K+LKK+ I+ D+ T
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFLTAL +FQT DRL FVMEY +GG+L F + R R F E RARFY AE+ AL++L
Sbjct: 206 R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYL 264
Query: 424 H-EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQ 482
H E V+YRDLKL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDN 324
Query: 483 EYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFM 542
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P L +A S+L G +
Sbjct: 325 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 384
Query: 543 TKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P +RLG GG A I H FF + W + ++KL PPF+P+V
Sbjct: 385 KKDPKQRLG--GGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV 429
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 301 bits (740), Expect = 4e-81
Identities = 139/287 (48%), Positives = 196/287 (68%), Gaps = 7/287 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
++ +F ++K+LGKG+FGKV+L + + T +A+K+LKK+ I+ D+ T
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFLTAL +FQT DRL FVMEY +GG+L F + R R F E RARFY AE+ AL++L
Sbjct: 206 R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYL 264
Query: 424 H-EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQ 482
H E V+YRDLKL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDN 324
Query: 483 EYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFM 542
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P L +A S+L G +
Sbjct: 325 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 384
Query: 543 TKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P +RLG GG A I H FF + W + ++KL PPF+P+V
Sbjct: 385 KKDPKQRLG--GGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV 429
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 301 bits (740), Expect = 4e-81
Identities = 139/287 (48%), Positives = 196/287 (68%), Gaps = 7/287 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
++ +F ++K+LGKG+FGKV+L + + T +A+K+LKK+ I+ D+ T
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFLTAL +FQT DRL FVMEY +GG+L F + R R F E RARFY AE+ AL++L
Sbjct: 206 R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYL 264
Query: 424 H-EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQ 482
H E V+YRDLKL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDN 324
Query: 483 EYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFM 542
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P L +A S+L G +
Sbjct: 325 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 384
Query: 543 TKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P +RLG GG A I H FF + W + ++KL PPF+P+V
Sbjct: 385 KKDPKQRLG--GGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV 429
>X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein
kinase protein.
Length = 479
Score = 299 bits (735), Expect = 1e-80
Identities = 161/360 (44%), Positives = 217/360 (60%), Gaps = 29/360 (8%)
Query: 297 CGGLKKP--SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTX 354
C L+K +LEDF F+ VLG+G FGKV+L+E R + E+FA+K LKK I+ D+ E
Sbjct: 139 CSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLM 198
Query: 355 --XXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFY 412
HPFL L FQT + + FVMEY GGDL+ I + F EPRA FY
Sbjct: 199 CEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLILHIH-SDVFSEPRAIFY 257
Query: 413 AAEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPD 472
+A V L L+FLHEH ++YRDLKLDN+LLD+EG+ K+ADFG+CKEG+ G T+TFCGTP+
Sbjct: 258 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 317
Query: 473 YIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSR 532
++APE+L + Y +VDWW LGVLLYEML G+ P D+E+++F+SI++D+V YP +LS
Sbjct: 318 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPLPGDDEEEVFDSIVNDEVRYPRFLSA 377
Query: 533 DAVSILKGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAG 591
+A+ I++ + + P RRLG A +K FFR + W+AL R+L PPF P +
Sbjct: 378 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL----- 432
Query: 592 EGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVA-PDVLRTINQEEFRGFSFV 650
+ + NFD EFT E P L+P L Q F F FV
Sbjct: 433 -----------------SGRTDISNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFV 475
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 189 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 246
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 366
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 367 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 426
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 427 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 471
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 94 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 151
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 271
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 272 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 331
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 332 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 376
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 94 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 151
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 271
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 272 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 331
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 332 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 376
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 189 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 246
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 366
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 367 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 426
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 427 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 471
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 189 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 246
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 366
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 367 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 426
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 427 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 471
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 108 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 165
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 166 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 225
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 226 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 285
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 286 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 345
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 346 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 390
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 94 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 151
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 271
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 272 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 331
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 332 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 376
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 84 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 141
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 142 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 201
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 202 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 261
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 262 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 321
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 322 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 366
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 94 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 151
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 271
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 272 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 331
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 332 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 376
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 297 bits (728), Expect = 1e-79
Identities = 138/285 (48%), Positives = 191/285 (67%), Gaps = 2/285 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
KPS DF F+KV+GKGSFGKV+LA + E +AVKVL+K AIL+ + +
Sbjct: 94 KPS--DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLL 151
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFL LH +FQT D+L+FV++Y++GG+L + +QR R F EPRARFYAAE+ AL
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH ++YRDLK +NILLDS+GH L DFG+CKE I TT+TFCGTP+Y+APE+L +
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHK 271
Query: 482 QEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGF 541
Q Y +VDWW LG +LYEML G PPF + N +++++IL+ + ++ A +L+G
Sbjct: 272 QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGL 331
Query: 542 MTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ K ++RLG IK+H FF ++WD L +K+ PPF P V
Sbjct: 332 LQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV 376
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 295 bits (723), Expect = 4e-79
Identities = 138/287 (48%), Positives = 195/287 (67%), Gaps = 8/287 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
++ +F ++K+LGKG+FGKV+L + + T +A+K+LKK+ I+ D+ T
Sbjct: 84 TMNEFEYLKLLGKGTFGKVILVKEKATA-YYAMKILKKEVIVAKDEVAHTLTENRVQQNS 142
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFLT L +FQT DRL FVMEY +GG+L F + R R F E RARFY AE+ AL++L
Sbjct: 143 R-HPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEIVSALDYL 201
Query: 424 H-EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQ 482
H E V+YRDLKL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 202 HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDN 261
Query: 483 EYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFM 542
+YG +VDWW LGV++YEM+ G+ PF + + LFE IL +++ +P L +A S+L G +
Sbjct: 262 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 321
Query: 543 TKAPSRRLGVCGG---AAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P +RLG GG A I H FF + W + ++KL PPF+P+V
Sbjct: 322 KKDPKQRLG--GGSEDAKEIMQHRFFTGIVWQHVYEKKLSPPFKPQV 366
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 292 bits (717), Expect = 2e-78
Identities = 160/358 (44%), Positives = 210/358 (58%), Gaps = 27/358 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K P L+DF + VLG+G FGKV+L + +GT + +A+K LKK +L D+ E
Sbjct: 552 KPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRIL 611
Query: 361 XXX--XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
HPFL +L FQT FV E+V GGDLM QI F EP+ARFY A V L
Sbjct: 612 EAVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHED-VFPEPQARFYVACVVL 670
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLHE +IYRDLKLDN+LLD++G K+ADFG+CKEGI G T+TFCGTP+++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L ++ Y +VDWWALGVLLYEML G+ PF D E+++F+ I++ D YP +LS + +
Sbjct: 731 LTQEAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFI 790
Query: 539 KGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
+ + K P +RLG A IK FFR +W AL R ++PPF P
Sbjct: 791 QKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVP------------- 837
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQE-EFRGFSFVNKDF 654
LC + F+ EFT P LTP AP L T Q+ FR F FV++ F
Sbjct: 838 -TLC--------GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERF 886
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 291 bits (715), Expect = 4e-78
Identities = 159/358 (44%), Positives = 209/358 (58%), Gaps = 27/358 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K P L+DF + VLG+G FGKV+L + +GT + +A+K LKK +L D+ E
Sbjct: 552 KPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRIL 611
Query: 361 XXX--XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
HPFL +L FQT FV E+V GGDLM QI F EP+ARFY A V L
Sbjct: 612 EAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHED-VFPEPQARFYVACVVL 670
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLHE +IYRDLKLDN+LLD++G K+ADFG+CKEGI G T+TFCGTP+++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L ++ Y +VDWW LGVLLYEML G+ PF D E+++F+ I++ D YP +LS + +
Sbjct: 731 LTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFI 790
Query: 539 KGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
+ + K P +RLG A IK FFR +W AL R ++PPF P
Sbjct: 791 QKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVP------------- 837
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQE-EFRGFSFVNKDF 654
LC + F+ EFT P LTP AP L T Q+ FR F FV++ F
Sbjct: 838 -TLC--------GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERF 886
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 291 bits (715), Expect = 4e-78
Identities = 159/358 (44%), Positives = 209/358 (58%), Gaps = 27/358 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K P L+DF + VLG+G FGKV+L + +GT + +A+K LKK +L D+ E
Sbjct: 552 KPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRIL 611
Query: 361 XXX--XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTL 418
HPFL +L FQT FV E+V GGDLM QI F EP+ARFY A V L
Sbjct: 612 EAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHED-VFPEPQARFYVACVVL 670
Query: 419 ALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEI 478
L+FLHE +IYRDLKLDN+LLD++G K+ADFG+CKEGI G T+TFCGTP+++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L ++ Y +VDWW LGVLLYEML G+ PF D E+++F+ I++ D YP +LS + +
Sbjct: 731 LTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFI 790
Query: 539 KGFMTKAPSRRLGVC-GGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAE 597
+ + K P +RLG A IK FFR +W AL R ++PPF P
Sbjct: 791 QKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVP------------- 837
Query: 598 GALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQE-EFRGFSFVNKDF 654
LC + F+ EFT P LTP AP L T Q+ FR F FV++ F
Sbjct: 838 -TLC--------GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERF 886
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 289 bits (710), Expect = 2e-77
Identities = 132/280 (47%), Positives = 186/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+++LH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIDYLHSL 153
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 274 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 313
>Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 274 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 313
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 334 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 373
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 274 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 313
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 274 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 313
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 334 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 373
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 288 bits (706), Expect = 5e-77
Identities = 132/280 (47%), Positives = 185/280 (66%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 274 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 313
>Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 285 bits (700), Expect = 3e-76
Identities = 132/280 (47%), Positives = 186/280 (66%), Gaps = 1/280 (0%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ ++ H
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKESHIMAERSVLLKNVR-H 92
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT ++L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 93 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 152
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 153 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 212
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 213 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 272
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+RLG IK H FF ++WD L ++L PPF P V
Sbjct: 273 RQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 312
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 285 bits (698), Expect = 5e-76
Identities = 134/280 (47%), Positives = 184/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKGSFGKV+LA+R+ +V+AVKVL+K +L + + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL LH +FQT ++L+FV+++V+GG+L F +QR R F E RARFYAAE+ AL +LH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
++YRDLK +NIL+DS GH L DFG+CKEGI TTTTFCGTP+Y+APE++++Q Y
Sbjct: 281 KIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + +++++ILH + +S A SIL+ + K
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAWSILEELLEKDR 400
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
RLG I+ H FF + W L Q+K+ PPF P V
Sbjct: 401 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNV 440
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 284 bits (697), Expect = 6e-76
Identities = 134/280 (47%), Positives = 183/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKGSFGKV+LA+R+ + +AVKVL+K +L + + H
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL LH +FQT ++L+FV+++V+GG+L F +QR R F E RARFYAAE+ AL +LH
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
++YRDLK +NILLDS GH L DFG+CKEGI TTTTFCGTP+Y+APE++++Q Y
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + +++++ILH + +S A SIL+ + K
Sbjct: 274 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 333
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
RLG I+ H FF + W L Q+K+ PPF P V
Sbjct: 334 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNV 373
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 284 bits (697), Expect = 6e-76
Identities = 134/280 (47%), Positives = 183/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKGSFGKV+LA+R+ + +AVKVL+K +L + + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL LH +FQT ++L+FV+++V+GG+L F +QR R F E RARFYAAE+ AL +LH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
++YRDLK +NILLDS GH L DFG+CKEGI TTTTFCGTP+Y+APE++++Q Y
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + +++++ILH + +S A SIL+ + K
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
RLG I+ H FF + W L Q+K+ PPF P V
Sbjct: 401 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNV 440
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 284 bits (697), Expect = 6e-76
Identities = 131/280 (46%), Positives = 183/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKG++GKV+LA+R+ +AVKVL+K +IL+ + H
Sbjct: 60 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 119
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL L +FQT + L+FV++YV+GG+L F +QR R+F EPRARFYAAEV A+ +LH
Sbjct: 120 PFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 179
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
+IYRDLK +NILLD +GH L DFG+CKEG+ TT+TFCGTP+Y+APE+L+++ Y
Sbjct: 180 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 239
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + + ++E+ILH + P + A +L+ + K
Sbjct: 240 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 299
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+R G IK H FF ++WD L ++L PPF P V
Sbjct: 300 RQRPGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV 339
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 284 bits (697), Expect = 6e-76
Identities = 134/280 (47%), Positives = 183/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKGSFGKV+LA+R+ + +AVKVL+K +L + + H
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL LH +FQT ++L+FV+++V+GG+L F +QR R F E RARFYAAE+ AL +LH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
++YRDLK +NILLDS GH L DFG+CKEGI TTTTFCGTP+Y+APE++++Q Y
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + +++++ILH + +S A SIL+ + K
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
RLG I+ H FF + W L Q+K+ PPF P V
Sbjct: 401 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNV 440
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 284 bits (697), Expect = 6e-76
Identities = 134/280 (47%), Positives = 183/280 (65%)
Query: 307 DFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXH 366
DF F+KV+GKGSFGKV+LA+R+ + +AVKVL+K +L + + H
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 367 PFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH 426
PFL LH +FQT ++L+FV+++V+GG+L F +QR R F E RARFYAAE+ AL +LH
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 427 GVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGC 486
++YRDLK +NILLDS GH L DFG+CKEGI TTTTFCGTP+Y+APE++++Q Y
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 487 SVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAP 546
+VDWW LG +LYEML G PPF + +++++ILH + +S A SIL+ + K
Sbjct: 274 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 333
Query: 547 SRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
RLG I+ H FF + W L Q+K+ PPF P V
Sbjct: 334 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNV 373
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 261 bits (640), Expect = 5e-69
Identities = 139/356 (39%), Positives = 206/356 (57%), Gaps = 27/356 (7%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K E F ++VLGKG +GKV + T ++FA+KVLKK I+++
Sbjct: 59 GPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK 118
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ L AFQT +L+ ++EY+ GG+L Q++R F E A FY AE
Sbjct: 119 AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAE 178
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+++AL LH+ G+IYRDLK +NI+L+ +GH KL DFG+CKE I DG T TFCGT +Y+A
Sbjct: 179 ISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMA 238
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PEIL + +VDWW+LG L+Y+ML G PPF +N + IL + P +L+++A
Sbjct: 239 PEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEAR 298
Query: 536 SILKGFMTKAPSRRLGVCGGAAG-IKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
+LK + + + RLG G AG ++AH FFR ++W+ L RK+ PPF+P
Sbjct: 299 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKP---------- 348
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
L +S+ + FD++FT++ PV +P + + NQ F GF++V
Sbjct: 349 ------------LLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQ-VFLGFTYV 391
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 261 bits (640), Expect = 5e-69
Identities = 139/356 (39%), Positives = 206/356 (57%), Gaps = 27/356 (7%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K E F ++VLGKG +GKV + T ++FA+KVLKK I+++
Sbjct: 82 GPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK 141
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ L AFQT +L+ ++EY+ GG+L Q++R F E A FY AE
Sbjct: 142 AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAE 201
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+++AL LH+ G+IYRDLK +NI+L+ +GH KL DFG+CKE I DG T TFCGT +Y+A
Sbjct: 202 ISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMA 261
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PEIL + +VDWW+LG L+Y+ML G PPF +N + IL + P +L+++A
Sbjct: 262 PEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEAR 321
Query: 536 SILKGFMTKAPSRRLGVCGGAAG-IKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
+LK + + + RLG G AG ++AH FFR ++W+ L RK+ PPF+P
Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKP---------- 371
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
L +S+ + FD++FT++ PV +P + + NQ F GF++V
Sbjct: 372 ------------LLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQ-VFLGFTYV 414
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 261 bits (640), Expect = 5e-69
Identities = 139/356 (39%), Positives = 206/356 (57%), Gaps = 27/356 (7%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K E F ++VLGKG +GKV + T ++FA+KVLKK I+++
Sbjct: 82 GPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK 141
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ L AFQT +L+ ++EY+ GG+L Q++R F E A FY AE
Sbjct: 142 AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAE 201
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+++AL LH+ G+IYRDLK +NI+L+ +GH KL DFG+CKE I DG T TFCGT +Y+A
Sbjct: 202 ISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMA 261
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PEIL + +VDWW+LG L+Y+ML G PPF +N + IL + P +L+++A
Sbjct: 262 PEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEAR 321
Query: 536 SILKGFMTKAPSRRLGVCGGAAG-IKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
+LK + + + RLG G AG ++AH FFR ++W+ L RK+ PPF+P
Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKP---------- 371
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
L +S+ + FD++FT++ PV +P + + NQ F GF++V
Sbjct: 372 ------------LLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQ-VFLGFTYV 414
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 254 bits (622), Expect = 7e-67
Identities = 136/347 (39%), Positives = 200/347 (57%), Gaps = 27/347 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
F ++VLGKG +GKV + +GT +++A+KVL+K I+++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 545 APSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP------------------- 347
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
C +S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 348 CL---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 390
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 254 bits (622), Expect = 7e-67
Identities = 136/347 (39%), Positives = 200/347 (57%), Gaps = 27/347 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
F ++VLGKG +GKV + +GT +++A+KVL+K I+++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 545 APSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP------------------- 347
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
C +S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 348 CL---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 390
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 254 bits (622), Expect = 7e-67
Identities = 136/347 (39%), Positives = 200/347 (57%), Gaps = 27/347 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
F ++VLGKG +GKV + +GT +++A+KVL+K I+++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 545 APSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP------------------- 347
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
C +S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 348 CL---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 390
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 254 bits (622), Expect = 7e-67
Identities = 136/347 (39%), Positives = 200/347 (57%), Gaps = 27/347 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
F ++VLGKG +GKV + +GT +++A+KVL+K I+++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 545 APSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP------------------- 347
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
C +S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 348 CL---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 390
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 254 bits (622), Expect = 7e-67
Identities = 136/347 (39%), Positives = 200/347 (57%), Gaps = 27/347 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
F ++VLGKG +GKV + +GT +++A+KVL+K I+++
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 199
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 200 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 259
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 260 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 319
Query: 545 APSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQL 603
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP
Sbjct: 320 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP------------------- 360
Query: 604 CFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
C +S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 361 CL---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 403
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 252 bits (617), Expect = 3e-66
Identities = 135/346 (39%), Positives = 199/346 (57%), Gaps = 26/346 (7%)
Query: 308 FTFIKVLGKGSFGKVMLAER-RGT-EEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
F ++VLGKG +GKV + +G +++A+KVL+K I+++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK 126
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHE 425
HPF+ L AFQT +L+ ++E + GG+L ++R F E A FY AE+TLAL LH
Sbjct: 127 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHS 186
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
G+IYRDLK +NI+L S+GH KL DFG+CKE I +G T TFCGT +Y+APEIL +
Sbjct: 187 QGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 246
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKA 545
+VDWW+LG L+Y+ML G PPF A+N + I+ + P +L+ DA ++K F+ +
Sbjct: 247 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 306
Query: 546 PSRRL-GVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVAEGALCQLC 604
PS+R+ G G AA ++ H FFR ++WD L ++ PPFRP C
Sbjct: 307 PSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP-------------------C 347
Query: 605 FRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+S+ + FD FT++ PV +P + + NQ F GF++V
Sbjct: 348 L---QSEEDVSQFDTRFTRQTPVDSPDDTALSESANQ-AFLGFTYV 389
>BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for
IMAGE:5496641) protein.
Length = 344
Score = 247 bits (604), Expect = 1e-64
Identities = 106/200 (53%), Positives = 144/200 (72%), Gaps = 1/200 (0%)
Query: 302 KPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXX 361
K ++ DF ++K+LGKG+FGKV+L + T +A+K+L+K+ I+ D+ T
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 362 XXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALE 421
HPFLTAL AFQT DRL FVMEY +GG+L F + R R F E RARFY AE+ ALE
Sbjct: 206 NTR-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALE 264
Query: 422 FLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQE 481
+LH V+YRD+KL+N++LD +GH K+ DFG+CKEGI DG T TFCGTP+Y+APE+L++
Sbjct: 265 YLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED 324
Query: 482 QEYGCSVDWWALGVLLYEML 501
+YG +VDWW LGV++YEM+
Sbjct: 325 NDYGRAVDWWGLGVVMYEMM 344
>AC017078-1|AAY14773.1| 238|Homo sapiens unknown protein.
Length = 238
Score = 245 bits (600), Expect = 3e-64
Identities = 116/231 (50%), Positives = 153/231 (66%), Gaps = 19/231 (8%)
Query: 23 VDLEPQGKLHLKIDLKWHSQXXXXXXXXXXXXXXXXXXXXXAPREFKEXXXXXXXXXXXX 82
+DLEP+G++++ IDL S R F+E
Sbjct: 1 IDLEPEGRVYVIIDLSGSS---------------GEAPKDNEERVFRERMRPRKRQGAVR 45
Query: 83 XXVHQVNGHKFMATFLRQPTFCSLCREFIWG-IGKQGYQCQVCTCVLHKRCHSLIVTKCP 141
VHQVNGHKFMAT+LRQPT+CS CR+FIWG IGKQGYQCQVCTCV+HKRCH LI+TKC
Sbjct: 46 RRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 105
Query: 142 GMKEEAGAGAVG-QGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVH 200
G+K++ VG Q FSVN+PH+F +H+YK TFCDHCGSLL+GL++QGLQC+ C MNVH
Sbjct: 106 GLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVH 165
Query: 201 KRCQKNVANNCGTNTKAMAALLNEMGISPDK--NPRPKTFKVTSSPQLPSP 249
+RC+ NVA NCG + + +A +L ++G++PDK N + K+ + + P P
Sbjct: 166 RRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQP 216
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 277 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 320
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 88 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 147
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 148 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 206
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 207 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 263
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 264 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 323
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 324 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 367
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 88 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 147
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 148 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 206
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 207 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 263
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 264 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 323
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 324 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 367
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 277 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 320
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 277 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 320
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 243 bits (595), Expect = 1e-63
Identities = 121/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 67 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 126
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 127 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 185
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 186 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 242
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 243 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 302
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 303 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 346
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 240 bits (588), Expect = 1e-62
Identities = 120/284 (42%), Positives = 170/284 (59%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+L+
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLN 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDIIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSNFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G + IK H +F DW A+ QRK+ PF PK R
Sbjct: 277 DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR 320
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 237 bits (581), Expect = 7e-62
Identities = 131/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 50 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 107
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 108 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 167
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 168 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 227
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 228 PEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ 287
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P V R
Sbjct: 288 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGR------ 341
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 342 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 379
Score = 112 bits (270), Expect = 3e-24
Identities = 69/211 (32%), Positives = 104/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ-------HPNIITLK 473
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 474 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 533
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ T C T +++APE+L+ Q Y + D
Sbjct: 534 KPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACD 593
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LG+LLY MLAG PF A+ DD E IL
Sbjct: 594 IWSLGILLYTMLAGFTPF-ANGPDDTPEEIL 623
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 237 bits (581), Expect = 7e-62
Identities = 131/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 50 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 107
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 108 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 167
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 168 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 227
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 228 PEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ 287
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P V R
Sbjct: 288 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGR------ 341
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 342 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 379
Score = 112 bits (270), Expect = 3e-24
Identities = 69/211 (32%), Positives = 104/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ-------HPNIITLK 473
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 474 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 533
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ T C T +++APE+L+ Q Y + D
Sbjct: 534 KPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACD 593
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LG+LLY MLAG PF A+ DD E IL
Sbjct: 594 IWSLGILLYTMLAGFTPF-ANGPDDTPEEIL 623
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 237 bits (581), Expect = 7e-62
Identities = 131/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 50 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 107
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 108 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 167
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 168 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 227
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 228 PEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ 287
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P V R
Sbjct: 288 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGR------ 341
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 342 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 379
Score = 112 bits (270), Expect = 3e-24
Identities = 69/211 (32%), Positives = 104/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ-------HPNIITLK 473
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 474 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 533
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ T C T +++APE+L+ Q Y + D
Sbjct: 534 KPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACD 593
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LG+LLY MLAG PF A+ DD E IL
Sbjct: 594 IWSLGILLYTMLAGFTPF-ANGPDDTPEEIL 623
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 237 bits (581), Expect = 7e-62
Identities = 131/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 123 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 180
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 181 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 240
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 241 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 300
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 301 PEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ 360
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P V R
Sbjct: 361 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGR------ 414
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 415 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 452
Score = 112 bits (270), Expect = 3e-24
Identities = 69/211 (32%), Positives = 104/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 494 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ-------HPNIITLK 546
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 547 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 606
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ T C T +++APE+L+ Q Y + D
Sbjct: 607 KPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACD 666
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LG+LLY MLAG PF A+ DD E IL
Sbjct: 667 IWSLGILLYTMLAGFTPF-ANGPDDTPEEIL 696
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 236 bits (578), Expect = 2e-61
Identities = 130/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 50 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 107
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 108 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 167
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 168 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 227
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 228 PEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ 287
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P + R
Sbjct: 288 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGR------ 341
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 342 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 379
Score = 112 bits (270), Expect = 3e-24
Identities = 69/211 (32%), Positives = 104/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ-------HPNIITLK 473
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 474 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 533
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ T C T +++APE+L+ Q Y + D
Sbjct: 534 KPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACD 593
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LG+LLY MLAG PF A+ DD E IL
Sbjct: 594 IWSLGILLYTMLAGFTPF-ANGPDDTPEEIL 623
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 236 bits (578), Expect = 2e-61
Identities = 130/356 (36%), Positives = 192/356 (53%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GS+GKV L + +G++ +++A+KVLKK + D
Sbjct: 51 GFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR--SK 108
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 109 MERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 168
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH K+ DFG+ KE I +FCGT +Y+A
Sbjct: 169 LALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMA 228
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 229 PEVVNRRGHTQSADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKAKLGMPQFLSGEAQ 288
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P RLG G IK H FF +DW+ L +++++PPF+P + R
Sbjct: 289 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGR------ 342
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ +FD EFT P +P P FRGFSFV
Sbjct: 343 ----------------PEDTFHFDPEFTARTPTDSPGVPPSANA--HHLFRGFSFV 380
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T+ +AVK++ K ++ E HP + L
Sbjct: 422 IGVGSYSVCKRCVHKATDTEYAVKIIGKSKRDPSEEIEILLRYGQ-------HPNIITLK 474
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ VME + GG+L+ +I R R F E A +T +++LH GV++RDL
Sbjct: 475 DVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDL 534
Query: 434 KLDNIL 439
K NIL
Sbjct: 535 KPSNIL 540
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 235 bits (576), Expect = 3e-61
Identities = 121/292 (41%), Positives = 173/292 (59%), Gaps = 6/292 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAE---RRGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L R + ++A+KVLKK A L+ D T
Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKK-ATLKVRDRVRTKM 111
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 112 ERDILADVN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 170
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ L L+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 171 LALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMA 230
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ Q + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 231 PEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQ 290
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
S+L+ + P+ RLG GA IK H F+ +DW+ L +R+++PPF+P V
Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAV 342
Score = 111 bits (267), Expect = 8e-24
Identities = 70/213 (32%), Positives = 107/213 (50%), Gaps = 12/213 (5%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
+ +G GS+ + + T +AVKV+ K ++ E HP +
Sbjct: 422 ETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ-------HPNIIT 474
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
L + ++ V E + GG+L+ +I R + F E A F + +E+LH GV++R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 432 DLKLDNIL-LDSEGH--C-KLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCS 487
DLK NIL +D G+ C ++ DFG K+ + T C T +++APE+L+ Q Y
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 488 VDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
D W+LG+LLY MLAG PF A+ D E IL
Sbjct: 595 CDIWSLGILLYTMLAGYTPF-ANGPSDTPEEIL 626
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 235 bits (576), Expect = 3e-61
Identities = 121/292 (41%), Positives = 173/292 (59%), Gaps = 6/292 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAE---RRGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L R + ++A+KVLKK A L+ D T
Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKK-ATLKVRDRVRTKM 111
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 112 ERDILADVN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 170
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ L L+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 171 LALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMA 230
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ Q + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 231 PEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQ 290
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
S+L+ + P+ RLG GA IK H F+ +DW+ L +R+++PPF+P V
Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAV 342
Score = 111 bits (267), Expect = 8e-24
Identities = 70/213 (32%), Positives = 107/213 (50%), Gaps = 12/213 (5%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
+ +G GS+ + + T +AVKV+ K ++ E HP +
Sbjct: 422 ETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ-------HPNIIT 474
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
L + ++ V E + GG+L+ +I R + F E A F + +E+LH GV++R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 432 DLKLDNIL-LDSEGH--C-KLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCS 487
DLK NIL +D G+ C ++ DFG K+ + T C T +++APE+L+ Q Y
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 488 VDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
D W+LG+LLY MLAG PF A+ D E IL
Sbjct: 595 CDIWSLGILLYTMLAGYTPF-ANGPSDTPEEIL 626
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 58 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 116
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 117 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 175
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 176 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 235
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 236 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 295
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 296 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 349
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 350 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 387
Score = 58.8 bits (136), Expect = 6e-08
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 12/147 (8%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L+
Sbjct: 427 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLN 479
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ + +V+ + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 480 DVYDD-GKYVYVVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 538
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKE 456
K NIL +D G+ ++ DFG K+
Sbjct: 539 KPSNILYVDESGNPESIRICDFGFAKQ 565
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein.
Length = 524
Score = 235 bits (575), Expect = 4e-61
Identities = 126/311 (40%), Positives = 187/311 (60%), Gaps = 11/311 (3%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEE---VFAVKVLKKDAILQDDDA-ECT 353
G +K S+E+F +KVLG G++GKV L + G + ++A+KVL+K A++Q E T
Sbjct: 23 GHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHT 82
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++YV GG++ + + + F E R Y
Sbjct: 83 RTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYG 142
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRDLKL+N+LLDSEGH L DFG+ KE + + T +FCGT +
Sbjct: 143 GEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIE 202
Query: 473 YIAPEILQEQE-YGCSVDWWALGVLLYEMLAGQPPF----EADNEDDLFESILHDDVLYP 527
Y+APEI++ + +G +VDWW+LG+LL+E+L G PF E + + ++ IL +P
Sbjct: 203 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 262
Query: 528 VWLSRDAVSILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ A +L+ + K P +RLG GA ++ H FF+ +DW ALA RK+ PFRP++
Sbjct: 263 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 322
Query: 587 RRVAGEGSVAE 597
R G+ AE
Sbjct: 323 RSELDVGNFAE 333
>BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for
IMAGE:5216639) protein.
Length = 556
Score = 235 bits (575), Expect = 4e-61
Identities = 126/311 (40%), Positives = 187/311 (60%), Gaps = 11/311 (3%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEE---VFAVKVLKKDAILQDDDA-ECT 353
G +K S+E+F +KVLG G++GKV L + G + ++A+KVL+K A++Q E T
Sbjct: 23 GHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHT 82
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++YV GG++ + + + F E R Y
Sbjct: 83 RTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYG 142
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRDLKL+N+LLDSEGH L DFG+ KE + + T +FCGT +
Sbjct: 143 GEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIE 202
Query: 473 YIAPEILQEQE-YGCSVDWWALGVLLYEMLAGQPPF----EADNEDDLFESILHDDVLYP 527
Y+APEI++ + +G +VDWW+LG+LL+E+L G PF E + + ++ IL +P
Sbjct: 203 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 262
Query: 528 VWLSRDAVSILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ A +L+ + K P +RLG GA ++ H FF+ +DW ALA RK+ PFRP++
Sbjct: 263 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 322
Query: 587 RRVAGEGSVAE 597
R G+ AE
Sbjct: 323 RSELDVGNFAE 333
Score = 64.9 bits (151), Expect = 9e-10
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
LG+GSF +R + + FAVK+L + +A T HP + LH
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRL-----EAN-TQREVAALRLCQSHPNVVNLH 470
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH-GVIYRD 432
+ + V+E + GG+L+ I++ R F E A + A+ F+HE GV++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 433 LKLDNILL--DSEG-HCKLADFGMCK 455
LK +NIL D+ G K+ DFG +
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFAR 556
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 235 bits (575), Expect = 4e-61
Identities = 126/311 (40%), Positives = 187/311 (60%), Gaps = 11/311 (3%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEE---VFAVKVLKKDAILQDDDA-ECT 353
G +K S+E+F +KVLG G++GKV L + G + ++A+KVL+K A++Q E T
Sbjct: 23 GHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHT 82
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++YV GG++ + + + F E R Y
Sbjct: 83 RTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYG 142
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRDLKL+N+LLDSEGH L DFG+ KE + + T +FCGT +
Sbjct: 143 GEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIE 202
Query: 473 YIAPEILQEQE-YGCSVDWWALGVLLYEMLAGQPPF----EADNEDDLFESILHDDVLYP 527
Y+APEI++ + +G +VDWW+LG+LL+E+L G PF E + + ++ IL +P
Sbjct: 203 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 262
Query: 528 VWLSRDAVSILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ A +L+ + K P +RLG GA ++ H FF+ +DW ALA RK+ PFRP++
Sbjct: 263 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 322
Query: 587 RRVAGEGSVAE 597
R G+ AE
Sbjct: 323 RSELDVGNFAE 333
Score = 109 bits (263), Expect = 2e-23
Identities = 72/200 (36%), Positives = 103/200 (51%), Gaps = 11/200 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
LG+GSF +R + + FAVK+L + +A T HP + LH
Sbjct: 410 LGQGSFSVCRRCRQRQSGQEFAVKILSRRL-----EAN-TQREVAALRLCQSHPNVVNLH 463
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH-GVIYRD 432
+ + V+E + GG+L+ I++ R F E A + A+ F+HE GV++RD
Sbjct: 464 EVHHDQPHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 523
Query: 433 LKLDNILL--DSEGH-CKLADFGMCK-EGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
LK +NIL D+ G K+ DFG + GV T C T Y APE+L +Q Y S
Sbjct: 524 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 583
Query: 489 DWWALGVLLYEMLAGQPPFE 508
D W+LGV+LY ML+GQ PF+
Sbjct: 584 DLWSLGVILYMMLSGQVPFQ 603
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 235 bits (575), Expect = 4e-61
Identities = 126/311 (40%), Positives = 187/311 (60%), Gaps = 11/311 (3%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEE---VFAVKVLKKDAILQDDDA-ECT 353
G +K S+E+F +KVLG G++GKV L + G + ++A+KVL+K A++Q E T
Sbjct: 23 GHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHT 82
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++YV GG++ + + + F E R Y
Sbjct: 83 RTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYG 142
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRDLKL+N+LLDSEGH L DFG+ KE + + T +FCGT +
Sbjct: 143 GEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIE 202
Query: 473 YIAPEILQEQE-YGCSVDWWALGVLLYEMLAGQPPF----EADNEDDLFESILHDDVLYP 527
Y+APEI++ + +G +VDWW+LG+LL+E+L G PF E + + ++ IL +P
Sbjct: 203 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 262
Query: 528 VWLSRDAVSILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ A +L+ + K P +RLG GA ++ H FF+ +DW ALA RK+ PFRP++
Sbjct: 263 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 322
Query: 587 RRVAGEGSVAE 597
R G+ AE
Sbjct: 323 RSELDVGNFAE 333
Score = 108 bits (260), Expect = 5e-23
Identities = 72/200 (36%), Positives = 103/200 (51%), Gaps = 11/200 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
LG+GSF +R + + FAVK+L + +A T HP + LH
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRL-----EAN-TQREVAALRLCQSHPNVVNLH 470
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH-GVIYRD 432
+ + V+E + GG+L+ I++ R F E A + A+ F+HE GV++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 433 LKLDNILL--DSEGH-CKLADFGMCK-EGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
LK +NIL D+ G K+ DFG + GV T C T Y APE+L +Q Y S
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 590
Query: 489 DWWALGVLLYEMLAGQPPFE 508
D W+LGV+LY ML+GQ PF+
Sbjct: 591 DLWSLGVILYMMLSGQVPFQ 610
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 235 bits (575), Expect = 4e-61
Identities = 126/311 (40%), Positives = 187/311 (60%), Gaps = 11/311 (3%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAERRGTEE---VFAVKVLKKDAILQDDDA-ECT 353
G +K S+E+F +KVLG G++GKV L + G + ++A+KVL+K A++Q E T
Sbjct: 7 GHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHT 66
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++YV GG++ + + + F E R Y
Sbjct: 67 RTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYG 126
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRDLKL+N+LLDSEGH L DFG+ KE + + T +FCGT +
Sbjct: 127 GEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIE 186
Query: 473 YIAPEILQEQE-YGCSVDWWALGVLLYEMLAGQPPF----EADNEDDLFESILHDDVLYP 527
Y+APEI++ + +G +VDWW+LG+LL+E+L G PF E + + ++ IL +P
Sbjct: 187 YMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFP 246
Query: 528 VWLSRDAVSILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
+ A +L+ + K P +RLG GA ++ H FF+ +DW ALA RK+ PFRP++
Sbjct: 247 PRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQI 306
Query: 587 RRVAGEGSVAE 597
R G+ AE
Sbjct: 307 RSELDVGNFAE 317
Score = 108 bits (260), Expect = 5e-23
Identities = 72/200 (36%), Positives = 103/200 (51%), Gaps = 11/200 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
LG+GSF +R + + FAVK+L + +A T HP + LH
Sbjct: 395 LGQGSFSVCRRCRQRQSGQEFAVKILSRRL-----EAN-TQREVAALRLCQSHPNVVNLH 448
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEH-GVIYRD 432
+ + V+E + GG+L+ I++ R F E A + A+ F+HE GV++RD
Sbjct: 449 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 508
Query: 433 LKLDNILL--DSEGH-CKLADFGMCK-EGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
LK +NIL D+ G K+ DFG + GV T C T Y APE+L +Q Y S
Sbjct: 509 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 568
Query: 489 DWWALGVLLYEMLAGQPPFE 508
D W+LGV+LY ML+GQ PF+
Sbjct: 569 DLWSLGVILYMMLSGQVPFQ 588
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 126 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 184
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 185 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 243
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 244 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 303
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 304 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 363
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 364 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 417
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 418 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 455
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 494 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 546
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 547 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 606
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 607 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 666
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 667 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 696
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 235 bits (575), Expect = 4e-61
Identities = 136/356 (38%), Positives = 196/356 (55%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER-RGTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G++ +++A+KVLKK A L+ D T
Sbjct: 45 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKM 103
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 104 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 162
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 163 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 222
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 223 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 282
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 283 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 336
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 337 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 374
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 414 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 466
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 467 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 526
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 527 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 586
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 587 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 616
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 235 bits (574), Expect = 5e-61
Identities = 135/356 (37%), Positives = 193/356 (54%), Gaps = 30/356 (8%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ +++A+KVLKK A L+ D T
Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKK-ATLKVRDRVRTKM 117
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 118 ERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGS 594
S+L+ + P+ RLG G IK H+FF +DW+ L +R++ PPF+P R
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR------ 350
Query: 595 VAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEFRGFSFV 650
+ FD EFT + P +P P + FRGFSFV
Sbjct: 351 ----------------PEDTFYFDPEFTAKTPKDSPGIPPSANA--HQLFRGFSFV 388
Score = 111 bits (266), Expect = 1e-23
Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ + T FAVK++ K ++ E HP + L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQ-------HPNIITLK 480
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
+ ++ V E + GG+L+ +I R + F E A +T +E+LH GV++RDL
Sbjct: 481 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 540
Query: 434 KLDNIL-LDSEGH---CKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL +D G+ ++ DFG K+ + T C T +++APE+L+ Q Y + D
Sbjct: 541 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVLLY ML G PF A+ DD E IL
Sbjct: 601 IWSLGVLLYTMLTGYTPF-ANGPDDTPEEIL 630
>BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 5 protein.
Length = 549
Score = 235 bits (574), Expect = 5e-61
Identities = 137/366 (37%), Positives = 204/366 (55%), Gaps = 39/366 (10%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQD-DDAECT 353
G +K +E+F +KVLG G++GKV L + T +++A+KVLKK I+Q E T
Sbjct: 39 GHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHT 98
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++Y++GG+L + + +F E + Y
Sbjct: 99 RTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYV 158
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRD+KL+NILLDS GH L DFG+ KE + D +FCGT +
Sbjct: 159 GEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIE 218
Query: 473 YIAPEILQEQEYG--CSVDWWALGVLLYEMLAGQPPFEADNED----DLFESILHDDVLY 526
Y+AP+I++ + G +VDWW+LGVL+YE+L G PF D E ++ IL + Y
Sbjct: 219 YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPY 278
Query: 527 PVWLSRDAVSILKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
P +S A +++ + K P +RLG CG A IK H FF+ ++WD LA +K+ PF+P
Sbjct: 279 PQEMSALAKDLIQRLLMKDPKKRLG-CGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP 337
Query: 585 KVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEF 644
+R + + NF EFT+ +P +P A L +++ F
Sbjct: 338 VIR----------------------DELDVSNFAEEFTEMDPTYSPAA---LPQSSEKLF 372
Query: 645 RGFSFV 650
+G+SFV
Sbjct: 373 QGYSFV 378
Score = 63.3 bits (147), Expect = 3e-09
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 6/123 (4%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K LG+GSF + + + FAVK++ K +A T HP +
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRM-----EAN-TQKEITALKLCEGHPNIVK 483
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
LH F + F VME ++GG+L +I++ + F E A + ++ A+ +H+ GV++R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543
Query: 432 DLK 434
DLK
Sbjct: 544 DLK 546
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 235 bits (574), Expect = 5e-61
Identities = 137/366 (37%), Positives = 204/366 (55%), Gaps = 39/366 (10%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQD-DDAECT 353
G +K +E+F +KVLG G++GKV L + T +++A+KVLKK I+Q E T
Sbjct: 39 GHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHT 98
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++Y++GG+L + + +F E + Y
Sbjct: 99 RTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYV 158
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRD+KL+NILLDS GH L DFG+ KE + D +FCGT +
Sbjct: 159 GEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIE 218
Query: 473 YIAPEILQEQEYG--CSVDWWALGVLLYEMLAGQPPFEADNED----DLFESILHDDVLY 526
Y+AP+I++ + G +VDWW+LGVL+YE+L G PF D E ++ IL + Y
Sbjct: 219 YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPY 278
Query: 527 PVWLSRDAVSILKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
P +S A +++ + K P +RLG CG A IK H FF+ ++WD LA +K+ PF+P
Sbjct: 279 PQEMSALAKDLIQRLLMKDPKKRLG-CGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP 337
Query: 585 KVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEF 644
+R + + NF EFT+ +P +P A L +++ F
Sbjct: 338 VIR----------------------DELDVSNFAEEFTEMDPTYSPAA---LPQSSEKLF 372
Query: 645 RGFSFV 650
+G+SFV
Sbjct: 373 QGYSFV 378
Score = 113 bits (273), Expect = 1e-24
Identities = 75/257 (29%), Positives = 124/257 (48%), Gaps = 20/257 (7%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K LG+GSF + + + VK++ K +A T HP +
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQALQVKIISKRM-----EAN-TQKEITALKLCEGHPNIVK 483
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
LH F + F VME ++GG+L +++ + F E A + ++ AL +H+ GV++R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 432 DLKLDNILLDSEG---HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
DLK +N+L E K+ DFG + D T C T PE+L + Y S
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESC 603
Query: 489 DWWALGVLLYEMLAGQPPFEADNED-------DLFESILHDDVLY--PVW--LSRDAVSI 537
D W+LGV+LY ML+GQ PF++ + ++ + I D + W +S++A +
Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663
Query: 538 LKGFMTKAPSRRLGVCG 554
++G +T P++RL + G
Sbjct: 664 IQGLLTVDPNKRLKMSG 680
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 235 bits (574), Expect = 5e-61
Identities = 137/366 (37%), Positives = 204/366 (55%), Gaps = 39/366 (10%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQD-DDAECT 353
G +K +E+F +KVLG G++GKV L + T +++A+KVLKK I+Q E T
Sbjct: 39 GHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHT 98
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++Y++GG+L + + +F E + Y
Sbjct: 99 RTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYV 158
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRD+KL+NILLDS GH L DFG+ KE + D +FCGT +
Sbjct: 159 GEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIE 218
Query: 473 YIAPEILQEQEYG--CSVDWWALGVLLYEMLAGQPPFEADNED----DLFESILHDDVLY 526
Y+AP+I++ + G +VDWW+LGVL+YE+L G PF D E ++ IL + Y
Sbjct: 219 YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPY 278
Query: 527 PVWLSRDAVSILKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
P +S A +++ + K P +RLG CG A IK H FF+ ++WD LA +K+ PF+P
Sbjct: 279 PQEMSALAKDLIQRLLMKDPKKRLG-CGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP 337
Query: 585 KVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEF 644
+R + + NF EFT+ +P +P A L +++ F
Sbjct: 338 VIR----------------------DELDVSNFAEEFTEMDPTYSPAA---LPQSSEKLF 372
Query: 645 RGFSFV 650
+G+SFV
Sbjct: 373 QGYSFV 378
Score = 124 bits (299), Expect = 1e-27
Identities = 79/257 (30%), Positives = 129/257 (50%), Gaps = 20/257 (7%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K LG+GSF + + + FAVK++ K +A T HP +
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRM-----EAN-TQKEITALKLCEGHPNIVK 483
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
LH F + F VME ++GG+L +I++ + F E A + ++ A+ +H+ GV++R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543
Query: 432 DLKLDNILLDSEG---HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
DLK +N+L E K+ DFG + D T C T Y APE+L + Y S
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESC 603
Query: 489 DWWALGVLLYEMLAGQPPFEADNED-------DLFESILHDDVLY--PVW--LSRDAVSI 537
D W+LGV+LY ML+GQ PF++ + ++ + I D + W +S++A +
Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663
Query: 538 LKGFMTKAPSRRLGVCG 554
++G +T P++RL + G
Sbjct: 664 IQGLLTVDPNKRLKMSG 680
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 235 bits (574), Expect = 5e-61
Identities = 137/366 (37%), Positives = 204/366 (55%), Gaps = 39/366 (10%)
Query: 298 GGLKKPSLEDFTFIKVLGKGSFGKVMLAER---RGTEEVFAVKVLKKDAILQD-DDAECT 353
G +K +E+F +KVLG G++GKV L + T +++A+KVLKK I+Q E T
Sbjct: 39 GHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHT 98
Query: 354 XXXXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYA 413
PFL LH AFQT +L +++Y++GG+L + + +F E + Y
Sbjct: 99 RTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYV 158
Query: 414 AEVTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT-TFCGTPD 472
E+ LALE LH+ G+IYRD+KL+NILLDS GH L DFG+ KE + D +FCGT +
Sbjct: 159 GEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIE 218
Query: 473 YIAPEILQEQEYG--CSVDWWALGVLLYEMLAGQPPFEADNED----DLFESILHDDVLY 526
Y+AP+I++ + G +VDWW+LGVL+YE+L G PF D E ++ IL + Y
Sbjct: 219 YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPY 278
Query: 527 PVWLSRDAVSILKGFMTKAPSRRLGVCG--GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
P +S A +++ + K P +RLG CG A IK H FF+ ++WD LA +K+ PF+P
Sbjct: 279 PQEMSALAKDLIQRLLMKDPKKRLG-CGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP 337
Query: 585 KVRRVAGEGSVAEGALCQLCFRLQKSKREAVNFDAEFTKEEPVLTPVAPDVLRTINQEEF 644
+R + + NF EFT+ +P +P A L +++ F
Sbjct: 338 VIR----------------------DELDVSNFAEEFTEMDPTYSPAA---LPQSSEKLF 372
Query: 645 RGFSFV 650
+G+SFV
Sbjct: 373 QGYSFV 378
Score = 124 bits (299), Expect = 1e-27
Identities = 79/257 (30%), Positives = 129/257 (50%), Gaps = 20/257 (7%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
K LG+GSF + + + FAVK++ K +A T HP +
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRM-----EAN-TQKEITALKLCEGHPNIVK 483
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
LH F + F VME ++GG+L +I++ + F E A + ++ A+ +H+ GV++R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543
Query: 432 DLKLDNILLDSEG---HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSV 488
DLK +N+L E K+ DFG + D T C T Y APE+L + Y S
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESC 603
Query: 489 DWWALGVLLYEMLAGQPPFEADNED-------DLFESILHDDVLY--PVW--LSRDAVSI 537
D W+LGV+LY ML+GQ PF++ + ++ + I D + W +S++A +
Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663
Query: 538 LKGFMTKAPSRRLGVCG 554
++G +T P++RL + G
Sbjct: 664 IQGLLTVDPNKRLKMSG 680
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 234 bits (573), Expect = 6e-61
Identities = 121/292 (41%), Positives = 172/292 (58%), Gaps = 6/292 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAE---RRGTEEVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L R + ++A+KVLKK A L+ D T
Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKK-ATLKVRDRVRTKM 111
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGDL ++ + F E +FY AE
Sbjct: 112 ERDILADVN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 170
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ L L+ LH G+IYRDLK +NILLD EGH KL DFG+ KE I +FCGT +Y+A
Sbjct: 171 LALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMA 230
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ Q + S DWW+ GVL++EML G PF+ + + IL + P +LS +A
Sbjct: 231 PEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQ 290
Query: 536 SILKGFMTKAPSRRLGV-CGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
S+L+ + P+ RLG GA IK H F+ +DW+ L +R++ PPF+P V
Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREITPPFKPAV 342
Score = 111 bits (267), Expect = 8e-24
Identities = 70/213 (32%), Positives = 107/213 (50%), Gaps = 12/213 (5%)
Query: 312 KVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTA 371
+ +G GS+ + + T +AVKV+ K ++ E HP +
Sbjct: 422 ETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ-------HPNIIT 474
Query: 372 LHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYR 431
L + ++ V E + GG+L+ +I R + F E A F + +E+LH GV++R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 432 DLKLDNIL-LDSEGH--C-KLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCS 487
DLK NIL +D G+ C ++ DFG K+ + T C T +++APE+L+ Q Y
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 488 VDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
D W+LG+LLY MLAG PF A+ D E IL
Sbjct: 595 CDIWSLGILLYTMLAGYTPF-ANGPSDTPEEIL 626
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 234 bits (572), Expect = 8e-61
Identities = 114/289 (39%), Positives = 175/289 (60%), Gaps = 6/289 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERR-GTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G + +++A+KVLKK ++ D
Sbjct: 64 GYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR--TK 121
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGD+ ++ + F E +FY AE
Sbjct: 122 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAE 181
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH+ G++YRDLK +NILLD GH KL DFG+ KE + +FCGT +Y+A
Sbjct: 182 LALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMA 241
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + ++ IL + P +LS +A
Sbjct: 242 PEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQ 301
Query: 536 SILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
S+L+ + P+ RLG G IK H FF ++DWD L +R+++PPF+P
Sbjct: 302 SLLRMLFKRNPANRLG-SEGVEEIKRHLFFANIDWDKLYKREVQPPFKP 349
Score = 98.7 bits (235), Expect = 6e-20
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ T FAVK++ K ++ E HP + L
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQ-------HPNIITLK 484
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
F ++ V + + GG+L+ +I + + F E A ++ +++LH GV++RDL
Sbjct: 485 DVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDL 544
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ + T C T +++APE+L +Q Y + D
Sbjct: 545 KPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACD 604
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVL Y MLAG PF A+ +D E IL
Sbjct: 605 IWSLGVLFYTMLAGYTPF-ANGPNDTPEEIL 634
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 234 bits (572), Expect = 8e-61
Identities = 114/289 (39%), Positives = 175/289 (60%), Gaps = 6/289 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERR-GTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G + +++A+KVLKK ++ D
Sbjct: 64 GYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR--TK 121
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGD+ ++ + F E +FY AE
Sbjct: 122 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAE 181
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH+ G++YRDLK +NILLD GH KL DFG+ KE + +FCGT +Y+A
Sbjct: 182 LALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMA 241
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + ++ IL + P +LS +A
Sbjct: 242 PEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQ 301
Query: 536 SILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
S+L+ + P+ RLG G IK H FF ++DWD L +R+++PPF+P
Sbjct: 302 SLLRMLFKRNPANRLG-SEGVEEIKRHLFFANIDWDKLYKREVQPPFKP 349
Score = 98.7 bits (235), Expect = 6e-20
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ T FAVK++ K ++ E HP + L
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQ-------HPNIITLK 484
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
F ++ V + + GG+L+ +I + + F E A ++ +++LH GV++RDL
Sbjct: 485 DVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDL 544
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ + T C T +++APE+L +Q Y + D
Sbjct: 545 KPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACD 604
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVL Y MLAG PF A+ +D E IL
Sbjct: 605 IWSLGVLFYTMLAGYTPF-ANGPNDTPEEIL 634
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 234 bits (572), Expect = 8e-61
Identities = 114/289 (39%), Positives = 175/289 (60%), Gaps = 6/289 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERR-GTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G + +++A+KVLKK ++ D
Sbjct: 64 GYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR--TK 121
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGD+ ++ + F E +FY AE
Sbjct: 122 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAE 181
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH+ G++YRDLK +NILLD GH KL DFG+ KE + +FCGT +Y+A
Sbjct: 182 LALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMA 241
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + ++ IL + P +LS +A
Sbjct: 242 PEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQ 301
Query: 536 SILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
S+L+ + P+ RLG G IK H FF ++DWD L +R+++PPF+P
Sbjct: 302 SLLRMLFKRNPANRLG-SEGVEEIKRHLFFANIDWDKLYKREVQPPFKP 349
Score = 98.7 bits (235), Expect = 6e-20
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ T FAVK++ K ++ E HP + L
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQ-------HPNIITLK 484
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
F ++ V + + GG+L+ +I + + F E A ++ +++LH GV++RDL
Sbjct: 485 DVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDL 544
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ + T C T +++APE+L +Q Y + D
Sbjct: 545 KPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACD 604
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVL Y MLAG PF A+ +D E IL
Sbjct: 605 IWSLGVLFYTMLAGYTPF-ANGPNDTPEEIL 634
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 233 bits (570), Expect = 1e-60
Identities = 117/284 (41%), Positives = 167/284 (58%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+ F IK LG GSFG+VML + + T +A+K+L K +++ E T
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L +F+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G IK H +F DW A+ QRK+ PF PK +
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK 320
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 233 bits (570), Expect = 1e-60
Identities = 117/284 (41%), Positives = 167/284 (58%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+ F IK LG GSFG+VML + + T +A+K+L K +++ E T
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L +F+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G IK H +F DW A+ QRK+ PF PK +
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK 320
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 233 bits (570), Expect = 1e-60
Identities = 117/284 (41%), Positives = 167/284 (58%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+ F IK LG GSFG+VML + + T +A+K+L K +++ E T
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L +F+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G IK H +F DW A+ QRK+ PF PK +
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK 320
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 233 bits (570), Expect = 1e-60
Identities = 117/284 (41%), Positives = 167/284 (58%), Gaps = 5/284 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
L+ F IK LG GSFG+VML + + T +A+K+L K +++ E T
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L +F+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTK 544
+VDWWALGVL+YEM AG PPF AD ++E I+ V +P S D +L+ +
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 545 APSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
++R G + G IK H +F DW A+ QRK+ PF PK +
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK 320
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 229 bits (561), Expect = 2e-59
Identities = 115/294 (39%), Positives = 175/294 (59%), Gaps = 8/294 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
SL+DF + +G G+FG+V L + + + FA+KV+ +++ E
Sbjct: 45 SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQ-EQHVHNEKSVLKE 103
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFL L + L+ +MEYV GG+L ++ +F FY+AE+ A+E+L
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H ++YRDLK +NILLD +GH KL DFG K+ ++D T T CGTP+Y+APE++Q +
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKK-LVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
+G +VDWWALG+L++EML+G PPF DN +++ IL + +P L ++K +
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLV 280
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVA 596
+RRLG + GA +K H +FR VDW+A+ QRKL+PP PK +AG+G +
Sbjct: 281 VDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPK---IAGDGDTS 331
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 229 bits (561), Expect = 2e-59
Identities = 115/294 (39%), Positives = 175/294 (59%), Gaps = 8/294 (2%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
SL+DF + +G G+FG+V L + + + FA+KV+ +++ E
Sbjct: 45 SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQ-EQHVHNEKSVLKE 103
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
HPFL L + L+ +MEYV GG+L ++ +F FY+AE+ A+E+L
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H ++YRDLK +NILLD +GH KL DFG K+ ++D T T CGTP+Y+APE++Q +
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKK-LVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
+G +VDWWALG+L++EML+G PPF DN +++ IL + +P L ++K +
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLV 280
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVRRVAGEGSVA 596
+RRLG + GA +K H +FR VDW+A+ QRKL+PP PK +AG+G +
Sbjct: 281 VDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPK---IAGDGDTS 331
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 227 bits (556), Expect = 7e-59
Identities = 112/289 (38%), Positives = 172/289 (59%), Gaps = 6/289 (2%)
Query: 299 GLKKPSLEDFTFIKVLGKGSFGKVMLAERR-GTE--EVFAVKVLKKDAILQDDDAECTXX 355
G +K F +KVLG+GSFGKV L ++ G + +++A+KVLKK ++
Sbjct: 64 GYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVR--GRVRTK 121
Query: 356 XXXXXXXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAE 415
HPF+ LH AFQT +L+ +++++ GGD+ ++ + F E +FY AE
Sbjct: 122 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAE 181
Query: 416 VTLALEFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIA 475
+ LAL+ LH+ G++YRDLK +NILLD GH KL DFG+ KE + +FCGT +Y+A
Sbjct: 182 LALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMA 241
Query: 476 PEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAV 535
PE++ + + S DWW+ GVL++EML G PF+ + ++ IL + P LS +A
Sbjct: 242 PEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQLLSAEAQ 301
Query: 536 SILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
S+L+ + P+ RLG G IK H FF ++DWD L + +++PPF+P
Sbjct: 302 SLLRMLFKRNPANRLG-SEGVEEIKRHLFFANIDWDKLYKGEVQPPFKP 349
Score = 98.7 bits (235), Expect = 6e-20
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 314 LGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHPFLTALH 373
+G GS+ T FAVK++ K ++ E HP + L
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQ-------HPNIITLK 484
Query: 374 CAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDL 433
F ++ V + + GG+L+ +I + + F E A ++ +++LH GV++RDL
Sbjct: 485 DVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDL 544
Query: 434 KLDNILLDSEG----HCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVD 489
K NIL E ++ DFG K+ + T C T +++APE+L +Q Y + D
Sbjct: 545 KPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACD 604
Query: 490 WWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
W+LGVL Y MLAG PF A+ +D E IL
Sbjct: 605 IWSLGVLFYTMLAGYTPF-ANGPNDTPEEIL 634
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 220 bits (537), Expect = 1e-56
Identities = 111/283 (39%), Positives = 165/283 (58%), Gaps = 5/283 (1%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
S + F ++ LG GSFG+VML + T +A+K+L K +++ E
Sbjct: 49 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVE-HILNEKRILQA 107
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
PFL L +F+ L+ VMEYV GG++ ++QR +F EP A FYAA+V LA+++L
Sbjct: 108 IDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYL 167
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H +I+RDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ +
Sbjct: 168 HSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKG 224
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
Y +VDWWALGVL+YEM G PPF AD ++E I+ V +P LS D +L+ +
Sbjct: 225 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKDLLRSLLQ 284
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPK 585
++R G + G IK H +F W A+ ++K+ PF PK
Sbjct: 285 VDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK 327
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 219 bits (536), Expect = 2e-56
Identities = 111/283 (39%), Positives = 165/283 (58%), Gaps = 5/283 (1%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
S + F ++ LG GSFG+VML + T +A+K+L K +++ E
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVE-HILNEKRILQA 98
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
PFL L +F+ L+ VMEYV GG++ ++QR +F EP A FYAA+V LA+++L
Sbjct: 99 IDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYL 158
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H +I+RDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ +
Sbjct: 159 HSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKG 215
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
Y +VDWWALGVL+YEM G PPF AD ++E I+ V +P LS D +L+ +
Sbjct: 216 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQ 275
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPK 585
++R G + G IK H +F W A+ ++K+ PF PK
Sbjct: 276 VDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK 318
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 219 bits (536), Expect = 2e-56
Identities = 111/283 (39%), Positives = 165/283 (58%), Gaps = 5/283 (1%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
S + F ++ LG GSFG+VML + T +A+K+L K +++ E
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVE-HILNEKRILQA 98
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
PFL L +F+ L+ VMEYV GG++ ++QR +F EP A FYAA+V LA+++L
Sbjct: 99 IDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYL 158
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H +I+RDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ +
Sbjct: 159 HSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKG 215
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
Y +VDWWALGVL+YEM G PPF AD ++E I+ V +P LS D +L+ +
Sbjct: 216 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQ 275
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPK 585
++R G + G IK H +F W A+ ++K+ PF PK
Sbjct: 276 VDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK 318
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 219 bits (536), Expect = 2e-56
Identities = 111/283 (39%), Positives = 165/283 (58%), Gaps = 5/283 (1%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
S + F ++ LG GSFG+VML + T +A+K+L K +++ E
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVE-HILNEKRILQA 98
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
PFL L +F+ L+ VMEYV GG++ ++QR +F EP A FYAA+V LA+++L
Sbjct: 99 IDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYL 158
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H +I+RDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ +
Sbjct: 159 HSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKG 215
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
Y +VDWWALGVL+YEM G PPF AD ++E I+ V +P LS D +L+ +
Sbjct: 216 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQ 275
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPK 585
++R G + G IK H +F W A+ ++K+ PF PK
Sbjct: 276 VDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK 318
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 219 bits (536), Expect = 2e-56
Identities = 111/283 (39%), Positives = 165/283 (58%), Gaps = 5/283 (1%)
Query: 304 SLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
S + F ++ LG GSFG+VML + T +A+K+L K +++ E
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVE-HILNEKRILQA 98
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
PFL L +F+ L+ VMEYV GG++ ++QR +F EP A FYAA+V LA+++L
Sbjct: 99 IDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYL 158
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H +I+RDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ +
Sbjct: 159 HSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKG 215
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMT 543
Y +VDWWALGVL+YEM G PPF AD ++E I+ V +P LS D +L+ +
Sbjct: 216 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQ 275
Query: 544 KAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPK 585
++R G + G IK H +F W A+ ++K+ PF PK
Sbjct: 276 VDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK 318
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 217 bits (530), Expect = 1e-55
Identities = 113/296 (38%), Positives = 165/296 (55%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K P DF IK++ G++G V L R T + FA+K + K ++ + +
Sbjct: 8 KPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 66
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ + C+F+TR L VMEYV+GGD ++ AR Y AE LAL
Sbjct: 67 LTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLAL 126
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 127 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 185
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ DD+
Sbjct: 186 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDI 245
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
L+P L +A ++ + P RLG GGA +K H+FFRD+DW L ++K
Sbjct: 246 LWPEGDEALPTEAQLLISSLLQTNPLVRLG-AGGAFEVKQHSFFRDLDWTGLLRQK 300
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 217 bits (530), Expect = 1e-55
Identities = 113/296 (38%), Positives = 165/296 (55%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K P DF IK++ G++G V L R T + FA+K + K ++ + +
Sbjct: 380 KPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 438
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ + C+F+TR L VMEYV+GGD ++ AR Y AE LAL
Sbjct: 439 LTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLAL 498
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 499 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 557
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ DD+
Sbjct: 558 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDI 617
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
L+P L +A ++ + P RLG GGA +K H+FFRD+DW L ++K
Sbjct: 618 LWPEGDEALPTEAQLLISSLLQTNPLVRLG-AGGAFEVKQHSFFRDLDWTGLLRQK 672
>AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein.
Length = 1308
Score = 208 bits (509), Expect = 4e-53
Identities = 109/295 (36%), Positives = 161/295 (54%), Gaps = 20/295 (6%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+KP DF IK++ G++G V L R T + FA+K + K ++ + +
Sbjct: 359 RKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQ-QVFVERDI 417
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F+TR L VMEYV+GGD ++ AR Y AE LAL
Sbjct: 418 LTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLAL 477
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTT--------------- 465
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ T
Sbjct: 478 EYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDK 537
Query: 466 TFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVL 525
CGTP+YIAPE++ Q YG VDWWA+GV+LYE L G PF D ++LF ++ D+++
Sbjct: 538 QVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIM 597
Query: 526 YPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
+P L DA ++ + ++P RLG GG +K H FF +DW L + K
Sbjct: 598 WPEGDEALPADAQDLITRLLRQSPLDRLGT-GGTHEVKQHPFFLALDWAGLLRHK 651
>BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 207 bits (506), Expect = 8e-53
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 143 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 201
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 202 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 261
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 262 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 320
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 321 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 380
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 381 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 435
>BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 207 bits (506), Expect = 8e-53
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 143 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 201
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 202 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 261
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 262 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 320
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 321 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 380
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 381 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 435
>AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein.
Length = 1734
Score = 207 bits (506), Expect = 8e-53
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein.
Length = 1329
Score = 207 bits (506), Expect = 8e-53
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 36 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 94
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 95 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 154
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 155 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM-SLTTNLYEGHIEKDAREFLD 213
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 214 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 273
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 274 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 328
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 390 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 448
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 449 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 508
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 509 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 567
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 682
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 390 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 448
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 449 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 508
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 509 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 567
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 682
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 390 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 448
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 449 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 508
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 509 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 567
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 682
>AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 207 bits (505), Expect = 1e-52
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
K PS EDF IK++ G++G V L + T + FA+K + K ++ + +
Sbjct: 505 KTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ-QAFVERDI 563
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ ++ C+F T+ L VMEYV+GGD ++ R Y AE LAL
Sbjct: 564 LTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLAL 623
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 624 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLM-SLTTNLYEGHIEKDAREFLD 682
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 525 LYPVW---LSRDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
++P L DA + + + P RLG G A +K H FF +DW L ++K
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK 797
>AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protein
kinase protein.
Length = 2434
Score = 206 bits (504), Expect = 1e-52
Identities = 107/296 (36%), Positives = 166/296 (56%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+KP DF IK++ G++G V + + + FA+K + K ++ + +
Sbjct: 374 RKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQ-QAFVERDI 432
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ +++C+F+TR L VMEYV+GGD ++ AR Y AE LAL
Sbjct: 433 LTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLAL 492
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 493 EYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLM-SMTTNLYEGHIEKDAREFLD 551
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 552 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 611
Query: 525 LYPVWLSR---DAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
+P DA ++ + + P RLG GGA +K H FFR +DW++L ++K
Sbjct: 612 NWPEKDEAPPPDAQDLITLLLRQNPLERLGT-GGAYEVKQHRFFRSLDWNSLLRQK 666
>AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein.
Length = 2137
Score = 206 bits (504), Expect = 1e-52
Identities = 107/296 (36%), Positives = 166/296 (56%), Gaps = 22/296 (7%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+KP DF IK++ G++G V + + + FA+K + K ++ + +
Sbjct: 77 RKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQ-QAFVERDI 135
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
+PF+ +++C+F+TR L VMEYV+GGD ++ AR Y AE LAL
Sbjct: 136 LTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLAL 195
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTF------------- 467
E+LH +G+++RDLK DN+L+ S GH KL DFG+ K G++ +TT +
Sbjct: 196 EYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLM-SMTTNLYEGHIEKDAREFLD 254
Query: 468 ---CGTPDYIAPEILQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDV 524
CGTP+YIAPE++ Q YG VDWWA+G++LYE L G PF D ++LF ++ D++
Sbjct: 255 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 314
Query: 525 LYPVWLSR---DAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRK 577
+P DA ++ + + P RLG GGA +K H FFR +DW++L ++K
Sbjct: 315 NWPEKDEAPPPDAQDLITLLLRQNPLERLGT-GGAYEVKQHRFFRSLDWNSLLRQK 369
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 203 bits (495), Expect = 2e-51
Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 4/216 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
+VDWWALGVL+YEM AG PPF AD ++E I+
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 203 bits (495), Expect = 2e-51
Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 4/216 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 47 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 106
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 107 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 165
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 166 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 222
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
+VDWWALGVL+YEM AG PPF AD ++E I+
Sbjct: 223 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 258
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 203 bits (495), Expect = 2e-51
Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 4/216 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 29 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 88
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 89 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 147
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 148 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 204
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
+VDWWALGVL+YEM AG PPF AD ++E I+
Sbjct: 205 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 240
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 203 bits (495), Expect = 2e-51
Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 4/216 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
+VDWWALGVL+YEM AG PPF AD ++E I+
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 203 bits (495), Expect = 2e-51
Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 4/216 (1%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXX 364
LEDF K LG GSFG+VML + + TE+ +A+K+L K +++ E T
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 365 XHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLH 424
PFL L AF+ L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH
Sbjct: 101 F-PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEY 484
+IYRDLK +N+L+D +G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y
Sbjct: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216
Query: 485 GCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL 520
+VDWWALGVL+YEM AG PPF AD ++E I+
Sbjct: 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252
>AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 321
Score = 197 bits (481), Expect = 9e-50
Identities = 93/207 (44%), Positives = 131/207 (63%), Gaps = 4/207 (1%)
Query: 382 LFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFLHEHGVIYRDLKLDNILLD 441
L+ VMEYV GG++ ++R +F EP ARFYAA++ L E+LH +IYRDLK +N+L+D
Sbjct: 87 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 146
Query: 442 SEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYGCSVDWWALGVLLYEML 501
+G+ ++ DFG K + G T T CGTP+Y+APEI+ + Y +VDWWALGVL+YEM
Sbjct: 147 HQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 203
Query: 502 AGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSILKGFMTKAPSRRLG-VCGGAAGIK 560
AG PPF AD ++E I+ V +P S D +L+ + ++R G + G + IK
Sbjct: 204 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIK 263
Query: 561 AHAFFRDVDWDALAQRKLRPPFRPKVR 587
H +F DW A+ QRK+ PF PK R
Sbjct: 264 THKWFATTDWIAIYQRKVEAPFIPKFR 290
Score = 45.6 bits (103), Expect = 6e-04
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKK 341
LEDF K LG GSFG+VML + + TE+ +A+K+L K
Sbjct: 44 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 80
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 196 bits (479), Expect = 2e-49
Identities = 112/293 (38%), Positives = 171/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF IKV+G+G+FG+V + + + TE ++A+K+L K +L+ + C
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
++TALH AFQ + L+ VM+Y GGDL+ + + K E ARFY E+ LA++ +H
Sbjct: 134 Q-WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 192
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DN+LLD GH +LADFG C + DG V ++ GTPDYI+PEILQ E
Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAME 252
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDD-VLYP---VWLSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I+ H++ +P +S +
Sbjct: 253 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 312
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RRLG G K HAFF ++W+ + R L P+ P V
Sbjct: 313 AKDLIQRLIC-SRERRLGQ-NGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV 361
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H+F + S+ T C HC SL+ GLI+QG CE CS H C+ C
Sbjct: 1026 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVC 1075
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/57 (33%), Positives = 27/57 (47%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEEA 147
H+F PT CS C + G+ +QGY C+VC+ H C CP E++
Sbjct: 1026 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQS 1082
>BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein.
Length = 492
Score = 196 bits (479), Expect = 2e-49
Identities = 112/293 (38%), Positives = 171/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF IKV+G+G+FG+V + + + TE ++A+K+L K +L+ + C
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
++TALH AFQ + L+ VM+Y GGDL+ + + K E ARFY E+ LA++ +H
Sbjct: 134 Q-WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 192
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DN+LLD GH +LADFG C + DG V ++ GTPDYI+PEILQ E
Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAME 252
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDD-VLYP---VWLSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I+ H++ +P +S +
Sbjct: 253 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 312
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RRLG G K HAFF ++W+ + R L P+ P V
Sbjct: 313 AKDLIQRLIC-SRERRLGQ-NGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV 361
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 196 bits (479), Expect = 2e-49
Identities = 112/293 (38%), Positives = 171/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF IKV+G+G+FG+V + + + TE ++A+K+L K +L+ + C
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
++TALH AFQ + L+ VM+Y GGDL+ + + K E ARFY E+ LA++ +H
Sbjct: 134 Q-WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 192
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DN+LLD GH +LADFG C + DG V ++ GTPDYI+PEILQ E
Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAME 252
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDD-VLYP---VWLSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I+ H++ +P +S +
Sbjct: 253 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 312
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RRLG G K HAFF ++W+ + R L P+ P V
Sbjct: 313 AKDLIQRLIC-SRERRLGQ-NGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV 361
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 196 bits (479), Expect = 2e-49
Identities = 112/293 (38%), Positives = 171/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF IKV+G+G+FG+V + + + TE ++A+K+L K +L+ + C
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
++TALH AFQ + L+ VM+Y GGDL+ + + K E ARFY E+ LA++ +H
Sbjct: 134 Q-WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 192
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DN+LLD GH +LADFG C + DG V ++ GTPDYI+PEILQ E
Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAME 252
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDD-VLYP---VWLSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I+ H++ +P +S +
Sbjct: 253 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 312
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RRLG G K HAFF ++W+ + R L P+ P V
Sbjct: 313 AKDLIQRLIC-SRERRLGQ-NGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV 361
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H+F + S+ T C HC SL+ GLI+QG CE CS H C+ C
Sbjct: 1026 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVC 1075
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/57 (33%), Positives = 27/57 (47%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEEA 147
H+F PT CS C + G+ +QGY C+VC+ H C CP E++
Sbjct: 1026 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQS 1082
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 196 bits (479), Expect = 2e-49
Identities = 112/293 (38%), Positives = 171/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF IKV+G+G+FG+V + + + TE ++A+K+L K +L+ + C
Sbjct: 123 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 182
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
++TALH AFQ + L+ VM+Y GGDL+ + + K E ARFY E+ LA++ +H
Sbjct: 183 Q-WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 241
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DN+LLD GH +LADFG C + DG V ++ GTPDYI+PEILQ E
Sbjct: 242 QLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAME 301
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDD-VLYP---VWLSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I+ H++ +P +S +
Sbjct: 302 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 361
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RRLG G K HAFF ++W+ + R L P+ P V
Sbjct: 362 AKDLIQRLIC-SRERRLGQ-NGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV 410
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNC 211
H+F + S+ T C HC SL+ GLI+QG CE CS H C+ C
Sbjct: 1075 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVC 1124
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/57 (33%), Positives = 27/57 (47%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEEA 147
H+F PT CS C + G+ +QGY C+VC+ H C CP E++
Sbjct: 1075 HQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQS 1131
>U33168-4|AAC50412.1| 500|Homo sapiens G protein-coupled receptor
kinase GRK4-delta protein.
Length = 500
Score = 196 bits (478), Expect = 2e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FIVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>U33168-3|AAC50409.1| 546|Homo sapiens G protein-coupled receptor
kinase GRK4-beta protein.
Length = 546
Score = 196 bits (478), Expect = 2e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FIVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>U33168-2|AAC50411.1| 532|Homo sapiens G protein-coupled receptor
kinase GRK4-gamma protein.
Length = 532
Score = 196 bits (478), Expect = 2e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FIVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>U33168-1|AAC50410.1| 578|Homo sapiens G protein-coupled receptor
kinase GRK4-alpha protein.
Length = 578
Score = 196 bits (478), Expect = 2e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FIVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>X98118-1|CAA66802.1| 532|Homo sapiens G protein-coupled receptor
kinase protein.
Length = 532
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>X97881-1|CAA66470.1| 578|Homo sapiens G-protein coupled receptor
kinase protein.
Length = 578
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>X97880-1|CAA66469.1| 546|Homo sapiens G-protein coupled receptor
kinase protein.
Length = 546
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>X97879-1|CAA66468.1| 500|Homo sapiens G-protein coupled receptor
kinase protein.
Length = 500
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>U33056-1|AAC50408.1| 532|Homo sapiens G protein-coupled receptor
kinase GRK4, gamma splice variant protein.
Length = 532
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>U33055-1|AAC50407.1| 546|Homo sapiens G protein-coupled receptor
kinase GRK4, beta splice variant protein.
Length = 546
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>U33054-1|AAC50406.1| 578|Homo sapiens G protein-coupled receptor
kinase GRK4, alpha splice variant protein.
Length = 578
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>L03718-1|AAB04045.1| 500|Homo sapiens G protein-coupled receptor
protein.
Length = 500
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>BC117320-1|AAI17321.1| 578|Homo sapiens G protein-coupled receptor
kinase 4 protein.
Length = 578
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 187 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 245
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 246 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 305
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 306 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 364
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 365 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 424
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 425 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 468
>AK223581-1|BAD97301.1| 500|Homo sapiens G protein-coupled receptor
kinase 2-like isoform 2 variant protein.
Length = 500
Score = 196 bits (477), Expect = 3e-49
Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Query: 308 FTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXXHP 367
F +VLGKG FG+V + R T +++A K L+K I + E
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI-KKRKGEAMALNEKRILEKVQSR 213
Query: 368 FLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARK--FDEPRARFYAAEVTLALEFLHE 425
F+ +L A++T+D L V+ ++GGDL F I FDE RA FYAAE+ LE L
Sbjct: 214 FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQR 273
Query: 426 HGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQEYG 485
++YRDLK +NILLD GH +++D G+ E I +G GT Y+APE++ ++Y
Sbjct: 274 ERIVYRDLKPENILLDDRGHIRISDLGLATE-IPEGQRVRGRVGTVGYMAPEVVNNEKYT 332
Query: 486 CSVDWWALGVLLYEMLAGQPPFEADNE----DDLFESILHDDVLYPVWLSRDAVSILKGF 541
S DWW LG L+YEM+ G PF+ E +++ + I +D Y S DA SI +
Sbjct: 333 FSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRML 392
Query: 542 MTKAPSRRLGVCG-GAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+TK PS+RLG G GAAG+K H F+D+++ L L PPF P
Sbjct: 393 LTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK428
protein.
Length = 496
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1070
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1071 -GPLGIDPQK 1079
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1068
>AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 976
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 977 -GPLGIDPQK 985
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 974
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1057
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1058 -GPLGIDPQK 1066
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1055
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1070
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1071 -GPLGIDPQK 1079
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1068
>AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 976
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 977 -GPLGIDPQK 985
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 974
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1057
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1058 -GPLGIDPQK 1066
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1055
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1070
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1071 -GPLGIDPQK 1079
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1013 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1068
>AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 976
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 977 -GPLGIDPQK 985
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 974
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1057
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1058 -GPLGIDPQK 1066
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1055
>AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 976
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 977 -GPLGIDPQK 985
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 974
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 313
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 314 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1057
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1058 -GPLGIDPQK 1066
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 1000 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1055
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 192 bits (468), Expect = 3e-48
Identities = 107/293 (36%), Positives = 170/293 (58%), Gaps = 17/293 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 86 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 144
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 145 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 204
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 205 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 264
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVW---LSRD 533
YG DWW+LGV +YEML G+ PF A++ + + I++ + +P +S +
Sbjct: 265 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSEN 324
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
A +++ + + RLG G K H FF +DWD + R P+ P+V
Sbjct: 325 AKDLIRRLIC-SREHRLGQ-NGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 373
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 983 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 1040
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 1041 -GPLGIDPQK 1049
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 983 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 1038
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 417 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 534
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 535 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 594
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 595 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 640
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 417 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 534
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 535 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 594
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 595 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 640
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1638
Score = 192 bits (467), Expect = 4e-48
Identities = 112/296 (37%), Positives = 169/296 (57%), Gaps = 23/296 (7%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
EDF +KV+G+G+FG+V + + + ++VFA+K+L K +L+ + C
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC-FREERDVLVNGD 133
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRAR-KFDEPRARFYAAEVTLALEFLH 424
+ ++T LH AFQ + L+ VM+Y GGDL+ + + + E ARFY AE+ +A++ +H
Sbjct: 134 NKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVH 193
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ ++RD+K DNIL+D GH +LADFG C + + DG V ++ GTPDYI+PEILQ E
Sbjct: 194 QLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAME 253
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
YG DWW+LGV +YEML G+ PF A++ + + I++ + VS
Sbjct: 254 DGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVS-- 311
Query: 539 KGFMTKAPSRRLGVCG-----GAAGI---KAHAFFRDVDWDALAQRKLRPPFRPKV 586
K P RRL +CG G +GI K H FF +DWD + R P+ P+V
Sbjct: 312 --ENAKDPIRRL-ICGREHRLGQSGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV 362
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANNCGTNTKAMAAL 221
H+F V S+ T C C SL+ GLI+QG CE C + H C C +
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK-- 976
Query: 222 LNEMGISPDK 231
+GI P K
Sbjct: 977 -GPLGIDPQK 985
Score = 40.3 bits (90), Expect = 0.021
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 91 HKFMATFLRQPTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCPGMKEE 146
H+F PT C C + G+ +QG C+VC H C + T CP E+
Sbjct: 919 HQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQ 974
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 405 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 463
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 464 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 522
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 523 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 582
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 583 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 628
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 405 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 463
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 464 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 522
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 523 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 582
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 583 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 628
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 405 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 463
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 464 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 522
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 523 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 582
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 583 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 628
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 432 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 549
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 609
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 610 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 655
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 192 bits (467), Expect = 4e-48
Identities = 104/286 (36%), Positives = 155/286 (54%), Gaps = 6/286 (2%)
Query: 305 LEDFTFIKVLGKGSFGKVMLAERRGTE-EVFAVKVLKKDAILQDDDAECTXXXXXXXXXX 363
L DF I LG G FG+V L + + E + FA+K+LKK I+ E
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 364 XXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLALEFL 423
F+ L+ F+ L+ +ME GG+L ++ F++ RFY A V A +L
Sbjct: 405 HSD-FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 463
Query: 424 HEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDGVTTTTFCGTPDYIAPEILQEQE 483
H G+IYRDLK +N++LD G+ KL DFG K+ I G T TFCGTP+Y+APEI+ +
Sbjct: 464 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK-IGFGKKTWTFCGTPEYVAPEIILNKG 522
Query: 484 YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPVWLSRDAVSILKGF 541
+ S D+W+LG+L+YE+L G PPF + + IL D + +P ++++A +++K
Sbjct: 523 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKL 582
Query: 542 MTKAPSRRLG-VCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKV 586
PS RLG + G I+ H +F +W+ L + L PP P V
Sbjct: 583 CRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSV 628
>S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase
protein.
Length = 625
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein.
Length = 582
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 28 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 87
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 88 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 146
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 147 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 206
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 207 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 266
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 267 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 315
>L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein.
Length = 624
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase
protein.
Length = 530
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase
protein.
Length = 535
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase
protein.
Length = 624
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase
protein.
Length = 629
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase,
Form VIII protein.
Length = 545
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 79 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 138
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 139 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 197
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 198 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 257
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 258 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 317
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 318 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 366
>L00727-3|AAA75239.1| 634|Homo sapiens myotonin-protein kinase,
Form VI protein.
Length = 634
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 79 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 138
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 139 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 197
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 198 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 257
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 258 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 317
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 318 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 366
>L00727-2|AAA75238.1| 609|Homo sapiens myotonin-protein kinase,
Form VII protein.
Length = 609
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 79 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 138
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 139 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 197
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 198 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 257
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 258 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 317
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 318 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 366
>L00727-1|AAA75236.1| 639|Homo sapiens myotonin-protein kinase,
Form I protein.
Length = 639
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 79 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 138
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 139 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 197
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 198 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 257
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 258 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 317
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 318 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 366
>BC062553-1|AAH62553.1| 629|Homo sapiens DMPK protein protein.
Length = 629
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 129 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 247
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 248 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 307
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 308 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 356
>BC026328-1|AAH26328.1| 655|Homo sapiens DMPK protein protein.
Length = 655
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 95 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDQ 154
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 155 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 213
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 214 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 273
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 274 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 333
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 334 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 382
>AB209363-1|BAD92600.1| 672|Homo sapiens myotonic dystrophy protein
kinase variant protein.
Length = 672
Score = 191 bits (465), Expect = 8e-48
Identities = 110/293 (37%), Positives = 162/293 (55%), Gaps = 19/293 (6%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+F +V + + + T +V+A+K++ K +L+ + C
Sbjct: 116 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 175
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQR-ARKFDEPRARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VMEY GGDL+ + + + ARFY AE+ +A++ +H
Sbjct: 176 R-WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 234
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQ--- 480
G ++RD+K DNILLD GH +LADFG C + DG V + GTPDY++PEILQ
Sbjct: 235 RLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVG 294
Query: 481 ----EQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILH--DDVLYPV---WLS 531
YG DWWALGV YEM GQ PF AD+ + + I+H + + P+ +
Sbjct: 295 GGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVP 354
Query: 532 RDAVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRP 584
+A ++ + P RLG GGA + H FF +DWD L R PPF P
Sbjct: 355 EEARDFIQRLLC-PPETRLG-RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTP 403
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 188 bits (459), Expect = 4e-47
Identities = 100/280 (35%), Positives = 155/280 (55%), Gaps = 5/280 (1%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+K EDF F K+LG+GSF V+LA T +A+K+L+K I++++
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPF L+ FQ ++L+F + Y G+L+ I++ FDE RFY AE+ AL
Sbjct: 135 SRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAL 193
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG--VTTTTFCGTPDYIAPEI 478
E+LH G+I+RDLK +NILL+ + H ++ DFG K + +F GT Y++PE+
Sbjct: 194 EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPEL 253
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L E+ S D WALG ++Y+++AG PPF A NE +F+ I+ + +P A ++
Sbjct: 254 LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLV 313
Query: 539 KGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQR 576
+ + ++RLG G +KAH FF V W+ L Q+
Sbjct: 314 EKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 188 bits (459), Expect = 4e-47
Identities = 100/280 (35%), Positives = 155/280 (55%), Gaps = 5/280 (1%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+K EDF F K+LG+GSF V+LA T +A+K+L+K I++++
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPF L+ FQ ++L+F + Y G+L+ I++ FDE RFY AE+ AL
Sbjct: 135 SRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAL 193
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG--VTTTTFCGTPDYIAPEI 478
E+LH G+I+RDLK +NILL+ + H ++ DFG K + +F GT Y++PE+
Sbjct: 194 EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPEL 253
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L E+ S D WALG ++Y+++AG PPF A NE +F+ I+ + +P A ++
Sbjct: 254 LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLV 313
Query: 539 KGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQR 576
+ + ++RLG G +KAH FF V W+ L Q+
Sbjct: 314 EKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 188 bits (459), Expect = 4e-47
Identities = 100/280 (35%), Positives = 155/280 (55%), Gaps = 5/280 (1%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+K EDF F K+LG+GSF V+LA T +A+K+L+K I++++
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPF L+ FQ ++L+F + Y G+L+ I++ FDE RFY AE+ AL
Sbjct: 135 SRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAL 193
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG--VTTTTFCGTPDYIAPEI 478
E+LH G+I+RDLK +NILL+ + H ++ DFG K + +F GT Y++PE+
Sbjct: 194 EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPEL 253
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L E+ S D WALG ++Y+++AG PPF A NE +F+ I+ + +P A ++
Sbjct: 254 LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLV 313
Query: 539 KGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQR 576
+ + ++RLG G +KAH FF V W+ L Q+
Sbjct: 314 EKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy
kinase-related CDC42-binding kinase gamma protein.
Length = 1551
Score = 188 bits (459), Expect = 4e-47
Identities = 111/294 (37%), Positives = 167/294 (56%), Gaps = 17/294 (5%)
Query: 306 EDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXXXXXXX 365
+DF +KV+G+G+FG+V + +R T ++FA+K+L K +L+ + C
Sbjct: 69 DDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREERDVLVKGDS 128
Query: 366 HPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPR-ARFYAAEVTLALEFLH 424
++T LH AFQ + L+ VM+Y GGDL+ + R P A+FY AE+ LA+ LH
Sbjct: 129 R-WVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLH 187
Query: 425 EHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG-VTTTTFCGTPDYIAPEILQEQE 483
+ G ++RD+K DN+LLD GH +LADFG C +G V ++ GTPDYI+PEILQ E
Sbjct: 188 QLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISPEILQAME 247
Query: 484 -----YGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESIL-HDDVL-YP---VWLSRD 533
YG DWW+LGV YE+L G+ PF A++ + + I+ H+D L +P +
Sbjct: 248 EGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPAS 307
Query: 534 AVSILKGFMTKAPSRRLGVCGGAAGIKAHAFFRDVDWDALAQRKLRPPFRPKVR 587
A +++ + + RLG GG + H FF VDW+ LA P+ P++R
Sbjct: 308 AQDLIRQLLCR-QEERLG-RGGLDDFRNHPFFEGVDWERLASS--TAPYIPELR 357
Score = 36.7 bits (81), Expect = 0.26
Identities = 17/42 (40%), Positives = 21/42 (50%)
Query: 162 HRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRC 203
H S+ T C C SL+ GL +QGL C+AC H C
Sbjct: 879 HTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTC 920
Score = 36.7 bits (81), Expect = 0.26
Identities = 43/167 (25%), Positives = 62/167 (37%), Gaps = 19/167 (11%)
Query: 101 PTFCSLCREFIWGIGKQGYQCQVCTCVLHKRCHSLIVTKCP----------GMKEEAGAG 150
PT C C + G+G+QG C C H C + CP G+ E G G
Sbjct: 889 PTKCLRCTSLMLGLGRQGLGCDACGYFCHTTC-APQAPPCPVPPDLLRTALGVHPETGTG 947
Query: 151 AVGQGFSVNVPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCEACSMNVHKRCQKNVANN 210
+GF ++VP V + F S L L+ ++ V +
Sbjct: 948 TAYEGF-LSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLR-----LSPPSGALLQVLDL 1001
Query: 211 CGTNTKAMAALLNEMGISPDKNPRPKTFKVTSSPQLPSPPTHCVTRL 257
A L +++ I P+ F+VT+S QL PPT C L
Sbjct: 1002 RDPQFSATPVLASDV-IHAQSRDLPRIFRVTTS-QLAVPPTTCTVLL 1046
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 188 bits (459), Expect = 4e-47
Identities = 100/280 (35%), Positives = 155/280 (55%), Gaps = 5/280 (1%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+K EDF F K+LG+GSF V+LA T +A+K+L+K I++++
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPF L+ FQ ++L+F + Y G+L+ I++ FDE RFY AE+ AL
Sbjct: 135 SRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAL 193
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG--VTTTTFCGTPDYIAPEI 478
E+LH G+I+RDLK +NILL+ + H ++ DFG K + +F GT Y++PE+
Sbjct: 194 EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPEL 253
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L E+ S D WALG ++Y+++AG PPF A NE +F+ I+ + +P A ++
Sbjct: 254 LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLV 313
Query: 539 KGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQR 576
+ + ++RLG G +KAH FF V W+ L Q+
Sbjct: 314 EKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 188 bits (459), Expect = 4e-47
Identities = 100/280 (35%), Positives = 155/280 (55%), Gaps = 5/280 (1%)
Query: 301 KKPSLEDFTFIKVLGKGSFGKVMLAERRGTEEVFAVKVLKKDAILQDDDAECTXXXXXXX 360
+K EDF F K+LG+GSF V+LA T +A+K+L+K I++++
Sbjct: 67 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 126
Query: 361 XXXXXHPFLTALHCAFQTRDRLFFVMEYVDGGDLMFQIQRARKFDEPRARFYAAEVTLAL 420
HPF L+ FQ ++L+F + Y G+L+ I++ FDE RFY AE+ AL
Sbjct: 127 SRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSAL 185
Query: 421 EFLHEHGVIYRDLKLDNILLDSEGHCKLADFGMCKEGIIDG--VTTTTFCGTPDYIAPEI 478
E+LH G+I+RDLK +NILL+ + H ++ DFG K + +F GT Y++PE+
Sbjct: 186 EYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPEL 245
Query: 479 LQEQEYGCSVDWWALGVLLYEMLAGQPPFEADNEDDLFESILHDDVLYPVWLSRDAVSIL 538
L E+ S D WALG ++Y+++AG PPF A NE +F+ I+ + +P A ++
Sbjct: 246 LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLV 305
Query: 539 KGFMTKAPSRRLGV--CGGAAGIKAHAFFRDVDWDALAQR 576
+ + ++RLG G +KAH FF V W+ L Q+
Sbjct: 306 EKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 345
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.139 0.439
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,844,158
Number of Sequences: 224733
Number of extensions: 3831877
Number of successful extensions: 16478
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2574
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 8026
Number of HSP's gapped (non-prelim): 4230
length of query: 660
length of database: 73,234,838
effective HSP length: 95
effective length of query: 565
effective length of database: 51,885,203
effective search space: 29315139695
effective search space used: 29315139695
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 68 (31.5 bits)
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