Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000777-TA|BGIBMGA000777-PA|IPR002018|Carboxylesterase,
type B
(1064 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for ... 149 5e-35
M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase pro... 149 5e-35
M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase prot... 149 5e-35
M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipas... 149 5e-35
AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase (... 149 5e-35
AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lip... 149 5e-35
AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase p... 149 5e-35
BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein. 149 7e-35
S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipas... 148 1e-34
BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked ... 138 1e-31
BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked ... 138 1e-31
AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein. 138 1e-31
BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked ... 135 7e-31
AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein. 135 7e-31
AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein. 135 7e-31
BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein. 132 8e-30
AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein. 130 3e-29
M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase pro... 128 8e-29
M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein. 128 8e-29
M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein. 128 8e-29
BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase p... 128 8e-29
AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein. 125 1e-27
BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein. 123 4e-27
BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7 prot... 123 4e-27
BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein. 123 4e-27
AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5 prot... 123 4e-27
AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens ... 123 4e-27
AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens ... 123 4e-27
BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein. 120 2e-26
AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein. 120 2e-26
AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein. 120 3e-26
BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein pr... 120 4e-26
BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein. 120 4e-26
BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein. 120 4e-26
AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo pr... 120 4e-26
AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform pr... 120 4e-26
AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform pr... 120 4e-26
AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HN... 120 4e-26
AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein. 120 4e-26
BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein. 119 6e-26
AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo pr... 119 6e-26
AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HN... 118 8e-26
Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein. 118 1e-25
U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein. 118 1e-25
D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precurso... 118 1e-25
BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein. 118 1e-25
BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein. 118 1e-25
BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2 (int... 118 1e-25
AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2 (int... 118 1e-25
AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isof... 118 1e-25
AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-relate... 112 7e-24
BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein. 111 2e-23
AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase ... 110 2e-23
X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage serin... 109 7e-23
S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholester... 109 7e-23
M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein. 109 7e-23
M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein. 109 7e-23
M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein. 109 7e-23
L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein. 109 7e-23
L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein. 109 7e-23
D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein. 109 7e-23
BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1 (mon... 109 7e-23
BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1 (mon... 109 7e-23
AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester hydro... 109 7e-23
AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein. 109 7e-23
AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b p... 109 7e-23
AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a p... 109 7e-23
AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b p... 109 7e-23
AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a p... 109 7e-23
AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase ... 109 7e-23
M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase prot... 107 2e-22
BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase, i... 107 2e-22
BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Y... 107 2e-22
BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein. 107 2e-22
AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (Y... 107 2e-22
AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase is... 107 2e-22
AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related acety... 107 2e-22
AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein. 107 2e-22
AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein. 107 2e-22
BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein. 107 3e-22
AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase ... 106 5e-22
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein. 103 3e-21
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein. 103 4e-21
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor... 103 4e-21
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein. 101 2e-20
BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for IM... 99 1e-19
BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein. 94 3e-18
AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens ... 93 5e-18
AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens ... 81 2e-14
BC032567-1|AAH32567.1| 134|Homo sapiens NLGN4Y protein protein. 44 0.002
D38441-1|BAA07476.1| 732|Homo sapiens acylamino acid-releasing ... 42 0.009
BC001826-1|AAH01826.1| 732|Homo sapiens N-acylaminoacyl-peptide... 42 0.009
BC001499-1|AAH01499.1| 732|Homo sapiens N-acylaminoacyl-peptide... 42 0.009
BC000362-1|AAH00362.1| 732|Homo sapiens N-acylaminoacyl-peptide... 42 0.009
AF141383-1|AAF37321.1| 732|Homo sapiens oxidized protein hydrol... 42 0.009
AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein. 36 0.77
L32179-1|AAA35551.1| 399|Homo sapiens arylacetamide deacetylase... 36 1.0
J03068-1|AAA35769.1| 606|Homo sapiens protein ( Human DNF1552 (... 36 1.0
BC032309-1|AAH32309.1| 399|Homo sapiens arylacetamide deacetyla... 36 1.0
BC075022-1|AAH75022.1| 543|Homo sapiens potassium channel, subf... 34 3.1
BC075021-1|AAH75021.1| 543|Homo sapiens potassium channel, subf... 34 3.1
AF385400-1|AAL95706.1| 543|Homo sapiens potassium channel TREK2... 34 3.1
AF385399-1|AAL95705.1| 543|Homo sapiens potassium channel TREK2... 34 3.1
AF279890-1|AAG15191.1| 538|Homo sapiens 2P domain potassium cha... 34 3.1
AK074522-1|BAC11039.1| 509|Homo sapiens protein ( Homo sapiens ... 33 5.4
>X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for
bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
Length = 745
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 345
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 346 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 402
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 458
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 459 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 518
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 519 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 572
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 366
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 423
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 483
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 513
>M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 345
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 346 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 402
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 458
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 459 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 518
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 519 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 572
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 366
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 423
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 483
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 513
>M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase
protein.
Length = 747
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 345
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 346 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 402
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 458
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 459 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 518
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 519 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 572
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 366
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 423
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 483
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 513
>M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipase
protein.
Length = 742
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 44 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 103
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 104 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 163
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 164 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 223
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 224 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 283
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 284 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 342
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 343 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 399
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 400 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 455
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 456 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 515
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 516 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 569
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 65 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 124
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 125 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 184
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 185 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 244
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 245 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 303
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 304 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 363
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 364 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 420
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 421 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 480
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 481 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 510
>AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase
(bile salt-stimulated lipase) protein.
Length = 756
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 345
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 346 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 402
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 458
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 459 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 518
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 519 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 572
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 366
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 423
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 483
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 513
>AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lipase
oncofetal isoform protein.
Length = 612
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 24 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 83
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 84 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 143
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 144 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 203
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 204 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 263
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 264 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 322
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 323 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 379
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 380 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 435
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 436 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 495
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 496 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 549
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 45 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 104
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 105 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 164
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 165 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 224
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 225 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 283
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 284 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 343
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 344 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 400
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 401 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 460
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 461 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 490
>AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 149 bits (361), Expect = 5e-35
Identities = 146/536 (27%), Positives = 232/536 (43%), Gaps = 49/536 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ +AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
LT+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY-ANAADIDYIAGTNNMDGH 345
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ + E+
Sbjct: 346 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDP--SQEN 402
Query: 458 HIEGLSLCFTDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVR 515
+ + TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADH 458
Query: 516 GDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTV 570
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 459 ADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTEN 518
Query: 571 PAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 519 SGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 572
Score = 140 bits (338), Expect = 3e-32
Identities = 128/451 (28%), Positives = 211/451 (46%), Gaps = 56/451 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVPED 875
V I DP+ L + ID I + + + + N K ED
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEED 366
Query: 876 FVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VK 929
F L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 FYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA 423
Query: 930 YAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAI 982
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV 483
Query: 983 QK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 SKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 513
>BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein.
Length = 722
Score = 149 bits (360), Expect = 7e-35
Identities = 149/531 (28%), Positives = 224/531 (42%), Gaps = 40/531 (7%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 47 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 106
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 107 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 166
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 167 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 226
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-TKIDNSLNLETADILTIL 354
LS ++ +AI++SG LS W + +NP +K+ E + + ++ + +T
Sbjct: 227 TLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 286
Query: 355 RAAQNIHFRPC--IEKGNNPFMTQTP---WGMIREQEVNITFMIGSANY-AGLNEALDQN 408
RA + P +E ++ P I +N+ +Y AG N
Sbjct: 287 RALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHI 346
Query: 409 EASIEQ--LNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCF 466
ASI+ +N + D S+ +R ++ + + + + E
Sbjct: 347 FASIDMPAINKGNKKVTEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTV 406
Query: 467 ----TDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRN 520
TD FL P I A+ ANA AK Y Y FS S + V GA D
Sbjct: 407 VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GADHADDIQ 462
Query: 521 YVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVTVPAQEE 575
YVF + T +R V M+ W F + G+P A T W T E
Sbjct: 463 YVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLE 522
Query: 576 WMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
+ +K+ L + L WT Y A PP D EAT
Sbjct: 523 ITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 571
Score = 142 bits (344), Expect = 6e-33
Identities = 128/450 (28%), Positives = 213/450 (47%), Gaps = 55/450 (12%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 127
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 128 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 187
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G + I +SG L
Sbjct: 188 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVAL 247
Query: 772 SPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PCVE 826
SP + NP+ A + E++G ++ ++ + L+ L A+K+ L P +
Sbjct: 248 SPWVIQKNPLFWAKKVAEKVGC-PVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLH 306
Query: 827 SVNNAE----SLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKLRHNSEKLKTVPEDF 876
V I DP+ L + ID I + + + + ++ K V EDF
Sbjct: 307 YVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEDF 366
Query: 877 VDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT-VKY 930
L+ EFT G+R K + + + +D + + ++ DVL + PT +
Sbjct: 367 YKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIAL 423
Query: 931 AVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNEAIQ 983
A A Y F++ + V + + + ++FG+ Y + +
Sbjct: 424 AQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVS 483
Query: 984 K-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
K + ++NF K GDP+ + A+P W+P
Sbjct: 484 KAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 512
>S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipase
protein.
Length = 742
Score = 148 bits (358), Expect = 1e-34
Identities = 145/537 (27%), Positives = 233/537 (43%), Gaps = 51/537 (9%)
Query: 130 GDIIS-YIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQ--LQGESVVGSQDCLTL 186
GD + + IP+A TK E P+ W+ T + + K RC Q + +S G +DCL L
Sbjct: 44 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYL 103
Query: 187 SIFAPTNAENVS----VLFHIHESNFVQGSADPA------LYGPEYLVSKGLILVLP-NY 235
+I+ P + VS V+ I+ F+ GS A LY E + ++G ++V+ NY
Sbjct: 104 NIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNY 163
Query: 236 RLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFL 295
R+GPLGFL + PGN L+D MA+ W+K NIA FGG+P+ I + GE GA +
Sbjct: 164 RVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQ 223
Query: 296 ALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEAL-------TKIDNSLNLETA 348
LS ++ AI++SG LS W + +NP +K+ E + ++ L +
Sbjct: 224 TLSPYNKGLIRAAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDP 283
Query: 349 DILTILRAA-------QNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAG- 400
+T+ +H+ + + F+ P + +I ++ G+ N G
Sbjct: 284 AAVTVAYKVPLAGLEYPMLHYVGFVPVIDEDFIPADPINLY-ANAADIDYIAGTNNMDGH 342
Query: 401 LNEALDQ---NEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLED 457
+ ++D N+ + + +DF L+ + + +V ++ + ++ ++
Sbjct: 343 IFASIDMPAINKGNKKVTEEDFYKLV-SEFTITKGLRGAKTTFDVYTESWAQDPS---QE 398
Query: 458 HIEGLSLCF-TDSCFLGPA-IRTARSLANA-GAKVYFYEFSFTELISESHTVDRPVEGAV 514
+ + + + F TD FL P I A+ ANA AK Y Y FS S + V GA
Sbjct: 399 NKKKIVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP---SRMPVYPKWV-GAD 454
Query: 515 RGDIRNYVFTQDGRILT-EGTAEREVVDIMVDTWFTFIENGNP----VANETDWNRLTVT 569
D YVF + T +R V M+ W F + G+P A T W T
Sbjct: 455 HADDIQYVFGKPFATPTGYRPQDRTVFKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 514
Query: 570 VPAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEAT 626
E + +K+ L + L WT Y A PP D EAT
Sbjct: 515 NSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS--EAT 569
Score = 140 bits (340), Expect = 2e-32
Identities = 133/453 (29%), Positives = 211/453 (46%), Gaps = 60/453 (13%)
Query: 613 PKPPPRWDGVFEATH-RVKCPQLDI------GDENCLVINIFTPE----VSNNLPVLVHV 661
P+P P W G +A + + +C Q I GDE+CL +NI+ P+ VS +LPV++ +
Sbjct: 65 PQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWI 124
Query: 662 HGGDYQNGWGFHQPPIN--------LINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGL 712
+GG + G G +N + +G +I+VTFNYR+G LGFL G PGN GL
Sbjct: 125 YGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGL 184
Query: 713 KDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSIL 771
+DQ A+ W+++NI FGGDPN++TL+G AG S+ L + G I +SG L
Sbjct: 185 RDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRAAISQSGVAL 244
Query: 772 SPTALTYNPIADAFAIGEQLG--YNDTNNSHKLLKYLRKLSVTVLLDAHKISL-----PC 824
SP + NP+ A + E++G D + LK +VTV A+K+ L P
Sbjct: 245 SPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPAAVTV---AYKVPLAGLEYPM 301
Query: 825 VESVNNA----ESLIDKDPLQLLKD-GPIDNIPMLVS-----YTRLKL-RHNSEKLKTVP 873
+ V E I DP+ L + ID I + + + + N K
Sbjct: 302 LHYVGFVPVIDEDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTE 361
Query: 874 EDFVDLLPSNLEFT-NDGIR-YKISELIKDFYFFKDIDTSSSYE---NYLNDVLMVYPT- 927
EDF L+ EFT G+R K + + + +D + + ++ DVL + PT
Sbjct: 362 EDFYKLVS---EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKIVVDFETDVLFLVPTE 418
Query: 928 VKYAVLYATKNYFNVYLMNFNYEADADV----LSEQNKKLVDFIFGE---NDLNYNKNNE 980
+ A A Y F++ + V + + + ++FG+ Y +
Sbjct: 419 IALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDR 478
Query: 981 AIQK-LTNLFSNFIKLGDPSPLITEAIPVIWQP 1012
+ K + ++NF K GDP+ + A+P W+P
Sbjct: 479 TVFKAMIAYWTNFAKTGDPN-MGDSAVPTHWEP 510
>BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 138 bits (333), Expect = 1e-31
Identities = 119/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P E ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 202
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 203 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 262
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + LK
Sbjct: 263 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKN 322
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 323 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 377
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 378 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 436
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 437 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 496
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 497 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Score = 127 bits (306), Expect = 2e-28
Identities = 111/437 (25%), Positives = 188/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G ++G +I+ Y+ +PYA + F+ P+S ++W
Sbjct: 41 SQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGI 100
Query: 160 HEVREHKSRCPQLQGESVV----------------------GSQDCLTLSIFAPTNAE-- 195
+ + CPQ E + ++DCL L+I+ P +
Sbjct: 101 RNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIH 160
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 161 EQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 218
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 219 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 278
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 279 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHI 338
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 339 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 395
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 396 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 455
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 456 TADLHAQYGSPTYFYAF 472
>BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 138 bits (333), Expect = 1e-31
Identities = 119/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P E ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 202
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 203 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 262
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + LK
Sbjct: 263 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKN 322
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 323 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 377
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 378 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 436
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 437 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 496
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 497 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Score = 127 bits (306), Expect = 2e-28
Identities = 111/437 (25%), Positives = 188/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G ++G +I+ Y+ +PYA + F+ P+S ++W
Sbjct: 41 SQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGI 100
Query: 160 HEVREHKSRCPQLQGESVV----------------------GSQDCLTLSIFAPTNAE-- 195
+ + CPQ E + ++DCL L+I+ P +
Sbjct: 101 RNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIH 160
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 161 EQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 218
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 219 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 278
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 279 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHI 338
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 339 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 395
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 396 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 455
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 456 TADLHAQYGSPTYFYAF 472
>AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein.
Length = 816
Score = 138 bits (333), Expect = 1e-31
Identities = 119/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P E ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 202
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 203 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 262
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + LK
Sbjct: 263 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKN 322
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 323 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 377
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 378 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 436
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 437 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 496
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 497 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Score = 127 bits (306), Expect = 2e-28
Identities = 111/437 (25%), Positives = 188/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G ++G +I+ Y+ +PYA + F+ P+S ++W
Sbjct: 41 SQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGI 100
Query: 160 HEVREHKSRCPQLQGESVV----------------------GSQDCLTLSIFAPTNAE-- 195
+ + CPQ E + ++DCL L+I+ P +
Sbjct: 101 RNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIH 160
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 161 EQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 218
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 219 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 278
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 279 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHI 338
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 339 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 395
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 396 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 455
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 456 TADLHAQYGSPTYFYAF 472
>BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked
protein.
Length = 816
Score = 135 bits (327), Expect = 7e-31
Identities = 117/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P + ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 143 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 202
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 203 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 262
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + L+
Sbjct: 263 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN 322
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 323 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 377
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 378 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 436
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 437 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 496
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 497 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Score = 129 bits (311), Expect = 6e-29
Identities = 113/437 (25%), Positives = 190/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G +RG +I+ Y+ +PYA + F+ P+ ++W
Sbjct: 41 SQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGI 100
Query: 160 HEVREHKSRCPQ-LQGESVVG---------------------SQDCLTLSIFAPTNAE-- 195
+ + CPQ L S++ ++DCL L+I+ PT +
Sbjct: 101 RNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIH 160
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 161 DQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 218
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 219 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 278
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 279 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHI 338
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 339 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 395
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 396 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 455
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 456 TADLHAQYGSPTYFYAF 472
>AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein.
Length = 816
Score = 135 bits (327), Expect = 7e-31
Identities = 117/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P + ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 143 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 202
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 203 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 262
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + L+
Sbjct: 263 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN 322
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 323 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 377
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 378 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 436
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 437 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 496
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 497 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Score = 129 bits (311), Expect = 6e-29
Identities = 113/437 (25%), Positives = 190/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G +RG +I+ Y+ +PYA + F+ P+ ++W
Sbjct: 41 SQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGI 100
Query: 160 HEVREHKSRCPQ-LQGESVVG---------------------SQDCLTLSIFAPTNAE-- 195
+ + CPQ L S++ ++DCL L+I+ PT +
Sbjct: 101 RNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIH 160
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 161 DQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 218
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 219 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 278
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 279 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHI 338
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 339 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 395
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 396 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 455
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 456 TADLHAQYGSPTYFYAF 472
>AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein.
Length = 817
Score = 135 bits (327), Expect = 7e-31
Identities = 117/401 (29%), Positives = 189/401 (47%), Gaps = 45/401 (11%)
Query: 638 DENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFN 690
+E+CL +NI+ P + ++ PV+V++HGG Y G G L + G +I++T N
Sbjct: 144 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITIN 203
Query: 691 YRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQL 750
YR+G+LGFL G AA GN GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + L
Sbjct: 204 YRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 263
Query: 751 LLQARLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK--- 804
L + G F K I++SG+ LS A+ Y P + +++G N DT + + L+
Sbjct: 264 LTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN 323
Query: 805 YLRKLSVTVLLDAHKISL-PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---L 860
Y + T+ + I+ P ++ +I DP L++ G N +++ + L
Sbjct: 324 YKELIQQTITPATYHIAFGPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 378
Query: 861 KLRHN--SEKLKTVPEDF---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSY 914
K + P DF V NL +G + + E IK Y + D + +
Sbjct: 379 KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETR 437
Query: 915 ENYL----NDVLMVYPTVKYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFI 967
L D V P V A L Y + YF + + E + V ++
Sbjct: 438 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYV 497
Query: 968 F-----GENDL---NYNKNNEAIQKLT-NLFSNFIKLGDPS 999
F G +L N++KN+ + + ++NF K GDP+
Sbjct: 498 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 538
Score = 129 bits (311), Expect = 6e-29
Identities = 113/437 (25%), Positives = 190/437 (43%), Gaps = 54/437 (12%)
Query: 107 SMEQNNLIETTHGLVRGFEWHTTGDIIS----YIDIPYAKYT---KYFEEPKSSNAWETT 159
S Q ++ T +G +RG +I+ Y+ +PYA + F+ P+ ++W
Sbjct: 42 SQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGI 101
Query: 160 HEVREHKSRCPQ-LQGESVVG---------------------SQDCLTLSIFAPTNAE-- 195
+ + CPQ L S++ ++DCL L+I+ PT +
Sbjct: 102 RNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIH 161
Query: 196 ----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMA 250
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A
Sbjct: 162 DQNSKKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAA 219
Query: 251 PGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAIT 310
GN L D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI
Sbjct: 220 KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAII 279
Query: 311 ESGSVLSYWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNI 360
+SG+ LS WA++ PA G + + ++ N +++ TI A +I
Sbjct: 280 QSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHI 339
Query: 361 HFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLND 417
F P I+ + P ++ + E +N M+G GL + + NE + +
Sbjct: 340 AFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 396
Query: 418 DFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIR 477
DF+ D +G + + ++ Y E + L FTD ++ PA+
Sbjct: 397 DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVA 456
Query: 478 TARSLANAGAKVYFYEF 494
TA A G+ YFY F
Sbjct: 457 TADLHAQYGSPTYFYAF 473
>BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein.
Length = 518
Score = 132 bits (318), Expect = 8e-30
Identities = 82/221 (37%), Positives = 116/221 (52%), Gaps = 33/221 (14%)
Query: 607 EMRNNAPKPPPRWDGVFEATHRVK-CPQ------------------LDI-------GDEN 640
E R P+PPP W G+ ATH CPQ LDI +E+
Sbjct: 81 EKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNED 140
Query: 641 CLVINIFTPEV-----SNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIG 694
CL +N++ P S PV+V++HGG Y G G L + G +I++T NYR+G
Sbjct: 141 CLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVG 200
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
VLGFL G AA GN GL DQ+ AL W+ +NI FGGDP +T++G+ G+ + LL +
Sbjct: 201 VLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS 260
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYN 794
G F + I++SGS LS A+ Y P+ + +++G N
Sbjct: 261 HHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCN 301
Score = 115 bits (276), Expect = 1e-24
Identities = 95/334 (28%), Positives = 156/334 (46%), Gaps = 24/334 (7%)
Query: 180 SQDCLTLSIFAPTNAE-----NVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP- 233
++DCL L+++ PT + V+ +IH ++++G+ + + L S G ++V+
Sbjct: 138 NEDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITL 195
Query: 234 NYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIG 293
NYR+G LGFL + A GN L D AL+W+ NIA FGG+P I V G G + +
Sbjct: 196 NYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVS 255
Query: 294 FLALSSSSRNYFDKAITESGSVLSYWALDRNP----ALTGEKL-TEALTKID--NSLNLE 346
L LS S F +AI +SGS LS WA++ P +L +K+ L +D + L +
Sbjct: 256 LLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQK 315
Query: 347 TADILT---ILRAAQNIHFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN 402
+A L I A ++ F P I+ + P ++ + E +N M+G GL
Sbjct: 316 SAKELVEQDIQPARYHVAFGPVID---GDVIPDDPEILMEQGEFLNYDVMLGVNQGEGLK 372
Query: 403 --EALDQNEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIE 460
E + E + + D++ D +G + + ++ Y E +
Sbjct: 373 FVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRK 432
Query: 461 GLSLCFTDSCFLGPAIRTARSLANAGAKVYFYEF 494
L FTD ++ P++ TA A G+ YFY F
Sbjct: 433 TLVALFTDHQWVEPSVVTADLHARYGSPTYFYAF 466
>AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein.
Length = 679
Score = 130 bits (313), Expect = 3e-29
Identities = 113/383 (29%), Positives = 179/383 (46%), Gaps = 39/383 (10%)
Query: 650 EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPG 708
E ++ PV+V++HGG Y G G L + G +I++T NYR+G+LGFL G AA G
Sbjct: 24 EQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKG 83
Query: 709 NVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILES 767
N GL DQ+ AL WI++N+ FGGDP VT++G+ AG+ + LL + G F K I++S
Sbjct: 84 NYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS 143
Query: 768 GSILSPTALTYNPIADAFAIGEQLGYN--DTNNSHKLLK---YLRKLSVTVLLDAHKISL 822
G+ LS A+ Y P + +++G N DT + + LK Y + T+ + I+
Sbjct: 144 GTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAF 203
Query: 823 -PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---LKLRHN--SEKLKTVPEDF 876
P ++ +I DP L++ G N +++ + LK + P DF
Sbjct: 204 GPVIDG-----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF 258
Query: 877 ---VDLLPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSYENYL----NDVLMVYPTV 928
V NL +G + + E IK Y + D + + L D V P V
Sbjct: 259 DFSVSNFVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAV 317
Query: 929 KYAVL---YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFIF-----GENDL---NYNK 977
A L Y + YF + + E + V ++F G +L N++K
Sbjct: 318 ATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSK 377
Query: 978 NNEAIQKLT-NLFSNFIKLGDPS 999
N+ + + ++NF K GDP+
Sbjct: 378 NDVMLSAVVMTYWTNFAKTGDPN 400
Score = 116 bits (279), Expect = 4e-25
Identities = 87/310 (28%), Positives = 142/310 (45%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A GN L
Sbjct: 31 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 88
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI +SG+ LS
Sbjct: 89 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 148
Query: 318 YWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNIHFRPCIE 367
WA++ PA G + + ++ N +++ TI A +I F P I+
Sbjct: 149 SWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVID 208
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL + + NE + + DF+
Sbjct: 209 ---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNF 265
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ PA+ TA A
Sbjct: 266 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQ 325
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 326 YGSPTYFYAF 335
>M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 128 bits (310), Expect = 8e-29
Identities = 141/564 (25%), Positives = 240/564 (42%), Gaps = 66/564 (11%)
Query: 109 EQNNLIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYTK---YFEEPKSSNAWETTHEVRE 164
E + +I T +G VRG G ++ ++ IPYA+ F++P+S W +
Sbjct: 29 EDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATK 88
Query: 165 HKSRCPQLQGESVVG-------------SQDCLTLSIFAPT-NAENVSVLFHIHESNFVQ 210
+ + C Q +S G S+DCL L+++ P +N +VL I+ F
Sbjct: 89 YANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQT 148
Query: 211 GSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLR-NTMAPGNAALKDLSMALQWIKN 268
G++ +Y ++L + +I+V NYR+G LGFL L N APGN L D +ALQW++
Sbjct: 149 GTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQK 208
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALD-----R 323
NIA FGGNP ++ + GE A + LS S + F +AI +SGS + WA+ R
Sbjct: 209 NIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR 268
Query: 324 NPALTGEKLT----EALTKIDNSL-NLETADIL------TILRAAQNIHFRPCIEKGNNP 372
N L KLT E T+I L N + +IL +++F P ++
Sbjct: 269 NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVD---GD 325
Query: 373 FMTQTPWGMIREQEVNITFMIGSAN---------YAGLNEALDQNE-ASIEQLNDDFATL 422
F+T P ++ + T ++ N Y + D N + ++ +
Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385
Query: 423 LPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSL 482
P FG +++++ + + + + +P E++ E L D F+ PA+ +
Sbjct: 386 FPGVSEFG----KESILFHY-TDWVDDQRP---ENYREALGDVVGDYNFICPALEFTKKF 437
Query: 483 ANAGAKVYFYEFSFTELISESHTVDRPV-EGAVRGDIRNYVFTQDGRILTEGTAEREVVD 541
+ G +FY F S + P G + G +VF T E++
Sbjct: 438 SEWGNNAFFYYFE-----HRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILS 492
Query: 542 -IMVDTWFTFIENGNPVANETDWNRLTVTVPAQEEWMQLGPE-IGLKQGLHLSRLNLWTN 599
+V W F + GNP + + V +++++ L E + L + WT+
Sbjct: 493 RSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTS 552
Query: 600 IYNNYFIEMRNNAPKPPPRWDGVF 623
+ +EM N + W F
Sbjct: 553 FFPK-VLEMTGNIDEAEWEWKAGF 575
Score = 114 bits (274), Expect = 2e-24
Identities = 65/152 (42%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Query: 632 PQLDIGDENCLVINIFTPEVS-NNLPVLVHVHGGDYQNGWG-FHQPPINLINK--GIIIV 687
P D+ E+CL +N++ P N VL+ ++GG +Q G H + + +I+V
Sbjct: 112 PNTDLS-EDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVV 170
Query: 688 TFNYRIGVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSI 746
+ NYR+G LGFL L G P APGN+GL DQ AL W+Q+NI FGG+P VTL+G AG+
Sbjct: 171 SMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAA 230
Query: 747 SIQL-LLQARLMMGFHKVILESGSILSPTALT 777
S+ L LL F + IL+SGS +P A+T
Sbjct: 231 SVSLHLLSPGSHSLFTRAILQSGSFNAPWAVT 262
>M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 128 bits (310), Expect = 8e-29
Identities = 141/564 (25%), Positives = 240/564 (42%), Gaps = 66/564 (11%)
Query: 109 EQNNLIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYTK---YFEEPKSSNAWETTHEVRE 164
E + +I T +G VRG G ++ ++ IPYA+ F++P+S W +
Sbjct: 29 EDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATK 88
Query: 165 HKSRCPQLQGESVVG-------------SQDCLTLSIFAPT-NAENVSVLFHIHESNFVQ 210
+ + C Q +S G S+DCL L+++ P +N +VL I+ F
Sbjct: 89 YANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQT 148
Query: 211 GSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLR-NTMAPGNAALKDLSMALQWIKN 268
G++ +Y ++L + +I+V NYR+G LGFL L N APGN L D +ALQW++
Sbjct: 149 GTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQK 208
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALD-----R 323
NIA FGGNP ++ + GE A + LS S + F +AI +SGS + WA+ R
Sbjct: 209 NIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR 268
Query: 324 NPALTGEKLT----EALTKIDNSL-NLETADIL------TILRAAQNIHFRPCIEKGNNP 372
N L KLT E T+I L N + +IL +++F P ++
Sbjct: 269 NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVD---GD 325
Query: 373 FMTQTPWGMIREQEVNITFMIGSAN---------YAGLNEALDQNE-ASIEQLNDDFATL 422
F+T P ++ + T ++ N Y + D N + ++ +
Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385
Query: 423 LPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSL 482
P FG +++++ + + + + +P E++ E L D F+ PA+ +
Sbjct: 386 FPGVSEFG----KESILFHY-TDWVDDQRP---ENYREALGDVVGDYNFICPALEFTKKF 437
Query: 483 ANAGAKVYFYEFSFTELISESHTVDRPV-EGAVRGDIRNYVFTQDGRILTEGTAEREVVD 541
+ G +FY F S + P G + G +VF T E++
Sbjct: 438 SEWGNNAFFYYFE-----HRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILS 492
Query: 542 -IMVDTWFTFIENGNPVANETDWNRLTVTVPAQEEWMQLGPE-IGLKQGLHLSRLNLWTN 599
+V W F + GNP + + V +++++ L E + L + WT+
Sbjct: 493 RSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTS 552
Query: 600 IYNNYFIEMRNNAPKPPPRWDGVF 623
+ +EM N + W F
Sbjct: 553 FFPK-VLEMTGNIDEAEWEWKAGF 575
Score = 114 bits (274), Expect = 2e-24
Identities = 65/152 (42%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Query: 632 PQLDIGDENCLVINIFTPEVS-NNLPVLVHVHGGDYQNGWG-FHQPPINLINK--GIIIV 687
P D+ E+CL +N++ P N VL+ ++GG +Q G H + + +I+V
Sbjct: 112 PNTDLS-EDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVV 170
Query: 688 TFNYRIGVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSI 746
+ NYR+G LGFL L G P APGN+GL DQ AL W+Q+NI FGG+P VTL+G AG+
Sbjct: 171 SMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAA 230
Query: 747 SIQL-LLQARLMMGFHKVILESGSILSPTALT 777
S+ L LL F + IL+SGS +P A+T
Sbjct: 231 SVSLHLLSPGSHSLFTRAILQSGSFNAPWAVT 262
>M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 128 bits (310), Expect = 8e-29
Identities = 141/564 (25%), Positives = 240/564 (42%), Gaps = 66/564 (11%)
Query: 109 EQNNLIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYTK---YFEEPKSSNAWETTHEVRE 164
E + +I T +G VRG G ++ ++ IPYA+ F++P+S W +
Sbjct: 29 EDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATK 88
Query: 165 HKSRCPQLQGESVVG-------------SQDCLTLSIFAPT-NAENVSVLFHIHESNFVQ 210
+ + C Q +S G S+DCL L+++ P +N +VL I+ F
Sbjct: 89 YANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQT 148
Query: 211 GSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLR-NTMAPGNAALKDLSMALQWIKN 268
G++ +Y ++L + +I+V NYR+G LGFL L N APGN L D +ALQW++
Sbjct: 149 GTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQK 208
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALD-----R 323
NIA FGGNP ++ + GE A + LS S + F +AI +SGS + WA+ R
Sbjct: 209 NIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR 268
Query: 324 NPALTGEKLT----EALTKIDNSL-NLETADIL------TILRAAQNIHFRPCIEKGNNP 372
N L KLT E T+I L N + +IL +++F P ++
Sbjct: 269 NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVD---GD 325
Query: 373 FMTQTPWGMIREQEVNITFMIGSAN---------YAGLNEALDQNE-ASIEQLNDDFATL 422
F+T P ++ + T ++ N Y + D N + ++ +
Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385
Query: 423 LPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSL 482
P FG +++++ + + + + +P E++ E L D F+ PA+ +
Sbjct: 386 FPGVSEFG----KESILFHY-TDWVDDQRP---ENYREALGDVVGDYNFICPALEFTKKF 437
Query: 483 ANAGAKVYFYEFSFTELISESHTVDRPV-EGAVRGDIRNYVFTQDGRILTEGTAEREVVD 541
+ G +FY F S + P G + G +VF T E++
Sbjct: 438 SEWGNNAFFYYFE-----HRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILS 492
Query: 542 -IMVDTWFTFIENGNPVANETDWNRLTVTVPAQEEWMQLGPE-IGLKQGLHLSRLNLWTN 599
+V W F + GNP + + V +++++ L E + L + WT+
Sbjct: 493 RSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTS 552
Query: 600 IYNNYFIEMRNNAPKPPPRWDGVF 623
+ +EM N + W F
Sbjct: 553 FFPK-VLEMTGNIDEAEWEWKAGF 575
Score = 114 bits (274), Expect = 2e-24
Identities = 65/152 (42%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Query: 632 PQLDIGDENCLVINIFTPEVS-NNLPVLVHVHGGDYQNGWG-FHQPPINLINK--GIIIV 687
P D+ E+CL +N++ P N VL+ ++GG +Q G H + + +I+V
Sbjct: 112 PNTDLS-EDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVV 170
Query: 688 TFNYRIGVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSI 746
+ NYR+G LGFL L G P APGN+GL DQ AL W+Q+NI FGG+P VTL+G AG+
Sbjct: 171 SMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAA 230
Query: 747 SIQL-LLQARLMMGFHKVILESGSILSPTALT 777
S+ L LL F + IL+SGS +P A+T
Sbjct: 231 SVSLHLLSPGSHSLFTRAILQSGSFNAPWAVT 262
>BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 128 bits (310), Expect = 8e-29
Identities = 141/564 (25%), Positives = 240/564 (42%), Gaps = 66/564 (11%)
Query: 109 EQNNLIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYTK---YFEEPKSSNAWETTHEVRE 164
E + +I T +G VRG G ++ ++ IPYA+ F++P+S W +
Sbjct: 29 EDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATK 88
Query: 165 HKSRCPQLQGESVVG-------------SQDCLTLSIFAPT-NAENVSVLFHIHESNFVQ 210
+ + C Q +S G S+DCL L+++ P +N +VL I+ F
Sbjct: 89 YANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQT 148
Query: 211 GSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLR-NTMAPGNAALKDLSMALQWIKN 268
G++ +Y ++L + +I+V NYR+G LGFL L N APGN L D +ALQW++
Sbjct: 149 GTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQK 208
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALD-----R 323
NIA FGGNP ++ + GE A + LS S + F +AI +SGS + WA+ R
Sbjct: 209 NIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR 268
Query: 324 NPALTGEKLT----EALTKIDNSL-NLETADIL------TILRAAQNIHFRPCIEKGNNP 372
N L KLT E T+I L N + +IL +++F P ++
Sbjct: 269 NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVD---GD 325
Query: 373 FMTQTPWGMIREQEVNITFMIGSAN---------YAGLNEALDQNE-ASIEQLNDDFATL 422
F+T P ++ + T ++ N Y + D N + ++ +
Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385
Query: 423 LPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSL 482
P FG +++++ + + + + +P E++ E L D F+ PA+ +
Sbjct: 386 FPGVSEFG----KESILFHY-TDWVDDQRP---ENYREALGDVVGDYNFICPALEFTKKF 437
Query: 483 ANAGAKVYFYEFSFTELISESHTVDRPV-EGAVRGDIRNYVFTQDGRILTEGTAEREVVD 541
+ G +FY F S + P G + G +VF T E++
Sbjct: 438 SEWGNNAFFYYFE-----HRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILS 492
Query: 542 -IMVDTWFTFIENGNPVANETDWNRLTVTVPAQEEWMQLGPE-IGLKQGLHLSRLNLWTN 599
+V W F + GNP + + V +++++ L E + L + WT+
Sbjct: 493 RSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTS 552
Query: 600 IYNNYFIEMRNNAPKPPPRWDGVF 623
+ +EM N + W F
Sbjct: 553 FFPK-VLEMTGNIDEAEWEWKAGF 575
Score = 114 bits (274), Expect = 2e-24
Identities = 65/152 (42%), Positives = 91/152 (59%), Gaps = 7/152 (4%)
Query: 632 PQLDIGDENCLVINIFTPEVS-NNLPVLVHVHGGDYQNGWG-FHQPPINLINK--GIIIV 687
P D+ E+CL +N++ P N VL+ ++GG +Q G H + + +I+V
Sbjct: 112 PNTDLS-EDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVV 170
Query: 688 TFNYRIGVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSI 746
+ NYR+G LGFL L G P APGN+GL DQ AL W+Q+NI FGG+P VTL+G AG+
Sbjct: 171 SMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAA 230
Query: 747 SIQL-LLQARLMMGFHKVILESGSILSPTALT 777
S+ L LL F + IL+SGS +P A+T
Sbjct: 231 SVSLHLLSPGSHSLFTRAILQSGSFNAPWAVT 262
>AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein.
Length = 816
Score = 125 bits (301), Expect = 1e-27
Identities = 109/376 (28%), Positives = 174/376 (46%), Gaps = 38/376 (10%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+G+LGFL G AA GN GL D
Sbjct: 168 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 227
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL WI++N+ FGGDP VT++G+ AG+ + LL + G F K I++SG+ LS
Sbjct: 228 QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 287
Query: 774 TALTYNPIADAFAIGEQLGYN--DTNNSHKLLK---YLRKLSVTVLLDAHKISL-PCVES 827
A+ Y P + +++G N DT + + L+ Y + T+ + I+ P ++
Sbjct: 288 WAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDG 347
Query: 828 VNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---LKLRHN--SEKLKTVPEDF---VDL 879
+I DP L++ G N +++ + LK + P DF V
Sbjct: 348 -----DVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSN 402
Query: 880 LPSNLEFTNDGIRYKISELIKDFYF-FKDIDTSSSYENYL----NDVLMVYPTV--KYAV 932
NL +G + + E IK Y + D + + L D V P V
Sbjct: 403 FVDNLYGYPEG-KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAADLHA 461
Query: 933 LYATKNYFNVYLMNFNYEADADVLSEQNKKLVDFIF-----GENDL---NYNKNNEAIQK 984
Y + YF + + E + V ++F G +L N++KN+ +
Sbjct: 462 QYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSA 521
Query: 985 LT-NLFSNFIKLGDPS 999
+ ++NF K GDP+
Sbjct: 522 VVMTYWTNFAKTGDPN 537
Score = 110 bits (264), Expect = 3e-23
Identities = 86/310 (27%), Positives = 141/310 (45%), Gaps = 20/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYRLG LGFL + A GN L
Sbjct: 169 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 226
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+WI+ N+ FGG+P + + G G + + L LS S F KAI +SG+ LS
Sbjct: 227 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 286
Query: 318 YWALDRNPA--------LTGEKLTEALTKIDNSLNLETADIL--TILRAAQNIHFRPCIE 367
WA++ PA G + + ++ N +++ TI A +I F P I+
Sbjct: 287 SWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVID 346
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL + + NE + + DF+
Sbjct: 347 ---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNF 403
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ PA+ A A
Sbjct: 404 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAV-AADLHAQ 462
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 463 YGSPTYFYAF 472
>BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 109 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 167
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 168 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 227
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 228 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 286
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 339
Score = 121 bits (292), Expect = 1e-26
Identities = 123/440 (27%), Positives = 194/440 (44%), Gaps = 36/440 (8%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 176
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 177 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 236
Query: 297 LSSSSRNYFDKAITESG-SVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILTILR 355
LS ++ F KAI ESG +++ Y L+ + E L N+ + ++ +L LR
Sbjct: 237 LSPMAKGLFHKAIMESGVAIIPY--LEAHDYEKSEDLQVVAHFCGNNAS-DSEALLRCLR 293
Query: 356 AAQNIHFRPCIEKG-------NNPFMTQTPWGMIREQEVN-ITFMIGSANY-AGLNEALD 406
+ +K + F P ++ ++ I +IG N+ G +
Sbjct: 294 TKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMK 353
Query: 407 QNEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPIT-LEDHIEGLSLC 465
+ + N A L ++ I Q + V ++YF + +T + D + L
Sbjct: 354 EAPEILSGSNKSLALHLIQNIL---HIPPQ-YLHLVANEYFHDKHSLTEIRDSLLDL--- 406
Query: 466 FTDSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIR---NYV 522
D F+ PA+ TAR +AGA VYFYEF E T V+ ++R
Sbjct: 407 LGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFED-TKPAFVKADHADEVRFVFGGA 465
Query: 523 FTQDGRILTEGTAERE--VVDIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQL 579
F + ++ EG E E + M+ W TF GNP N+ W +T E+++QL
Sbjct: 466 FLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQL 521
Query: 580 GPEIGLKQGLHLSRLNLWTN 599
+ L Q L R++ WT+
Sbjct: 522 DLNMSLGQRLKEPRVDFWTS 541
>BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7
protein.
Length = 525
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 109 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 167
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 168 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 227
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 228 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 286
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 339
Score = 90.2 bits (214), Expect = 3e-17
Identities = 53/143 (37%), Positives = 76/143 (53%), Gaps = 5/143 (3%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 176
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 177 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 236
Query: 297 LSSSSRNYFDKAITESG-SVLSY 318
LS ++ F KAI ESG +++ Y
Sbjct: 237 LSPMAKGLFHKAIMESGVAIIPY 259
Score = 35.1 bits (77), Expect = 1.3
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
Query: 532 EGTAEREVV--DIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQLGPEIGLKQG 588
EG E E + M+ W TF GNP N+ W +T E+++QL + L Q
Sbjct: 425 EGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQLDLNMSLGQR 480
Query: 589 LHLSRLNLWTN 599
L R++ WT+
Sbjct: 481 LKEPRVDFWTS 491
>BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 109 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 167
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 168 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 227
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 228 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 286
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 339
Score = 121 bits (292), Expect = 1e-26
Identities = 123/440 (27%), Positives = 194/440 (44%), Gaps = 36/440 (8%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 176
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 177 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 236
Query: 297 LSSSSRNYFDKAITESG-SVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILTILR 355
LS ++ F KAI ESG +++ Y L+ + E L N+ + ++ +L LR
Sbjct: 237 LSPMAKGLFHKAIMESGVAIIPY--LEAHDYEKSEDLQVVAHFCGNNAS-DSEALLRCLR 293
Query: 356 AAQNIHFRPCIEKG-------NNPFMTQTPWGMIREQEVN-ITFMIGSANY-AGLNEALD 406
+ +K + F P ++ ++ I +IG N+ G +
Sbjct: 294 TKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMK 353
Query: 407 QNEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPIT-LEDHIEGLSLC 465
+ + N A L ++ I Q + V ++YF + +T + D + L
Sbjct: 354 EAPEILSGSNKSLALHLIQNIL---HIPPQ-YLHLVANEYFHDKHSLTEIRDSLLDL--- 406
Query: 466 FTDSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIR---NYV 522
D F+ PA+ TAR +AGA VYFYEF E T V+ ++R
Sbjct: 407 LGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFED-TKPAFVKADHADEVRFVFGGA 465
Query: 523 FTQDGRILTEGTAERE--VVDIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQL 579
F + ++ EG E E + M+ W TF GNP N+ W +T E+++QL
Sbjct: 466 FLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQL 521
Query: 580 GPEIGLKQGLHLSRLNLWTN 599
+ L Q L R++ WT+
Sbjct: 522 DLNMSLGQRLKEPRVDFWTS 541
>AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5
protein.
Length = 575
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 109 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 167
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 168 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 227
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 228 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 286
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 339
Score = 121 bits (292), Expect = 1e-26
Identities = 123/440 (27%), Positives = 194/440 (44%), Gaps = 36/440 (8%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 176
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 177 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 236
Query: 297 LSSSSRNYFDKAITESG-SVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILTILR 355
LS ++ F KAI ESG +++ Y L+ + E L N+ + ++ +L LR
Sbjct: 237 LSPMAKGLFHKAIMESGVAIIPY--LEAHDYEKSEDLQVVAHFCGNNAS-DSEALLRCLR 293
Query: 356 AAQNIHFRPCIEKG-------NNPFMTQTPWGMIREQEVN-ITFMIGSANY-AGLNEALD 406
+ +K + F P ++ ++ I +IG N+ G +
Sbjct: 294 TKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMK 353
Query: 407 QNEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPIT-LEDHIEGLSLC 465
+ + N A L ++ I Q + V ++YF + +T + D + L
Sbjct: 354 EAPEILSGSNKSLALHLIQNIL---HIPPQ-YLHLVANEYFHDKHSLTEIRDSLLDL--- 406
Query: 466 FTDSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIR---NYV 522
D F+ PA+ TAR +AGA VYFYEF E T V+ ++R
Sbjct: 407 LGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFED-TKPAFVKADHADEVRFVFGGA 465
Query: 523 FTQDGRILTEGTAERE--VVDIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQL 579
F + ++ EG E E + M+ W TF GNP N+ W +T E+++QL
Sbjct: 466 FLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQL 521
Query: 580 GPEIGLKQGLHLSRLNLWTN 599
+ L Q L R++ WT+
Sbjct: 522 DLNMSLGQRLKEPRVDFWTS 541
>AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 469
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 3 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 61
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 62 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 121
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 122 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 180
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 181 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 233
Score = 120 bits (288), Expect = 4e-26
Identities = 123/438 (28%), Positives = 189/438 (43%), Gaps = 32/438 (7%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 12 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 70
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 71 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 130
Query: 297 LSSSSRNYFDKAITESG-SVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILTILR 355
LS ++ F KAI ESG +++ Y L+ + E L N+ + ++ +L LR
Sbjct: 131 LSPMAKGLFHKAIMESGVAIIPY--LEAHDYEKSEDLQVVAHFCGNNAS-DSEALLRCLR 187
Query: 356 AAQNIHFRPCIEKG-------NNPFMTQTPWGMIREQEVNITFMIGSANYAGLNEALDQN 408
+ +K + F P ++ ++ I N L
Sbjct: 188 TKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNSHECGFLLPMK 247
Query: 409 EASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPIT-LEDHIEGLSLCFT 467
EA E L+ +L + I Q + V ++YF + +T + D + L
Sbjct: 248 EAP-EILSGSNKSLALHLIQNILHIPPQ-YLHLVANEYFHDKHSLTEIRDSLLDL---LG 302
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIR---NYVFT 524
D F+ PA+ TAR +AGA VYFYEF E T V+ ++R F
Sbjct: 303 DVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFED-TKPAFVKADHADEVRFVFGGAFL 361
Query: 525 QDGRILTEGTAERE--VVDIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQLGP 581
+ ++ EG E E + M+ W TF GNP N+ W +T E+++QL
Sbjct: 362 KGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQLDL 417
Query: 582 EIGLKQGLHLSRLNLWTN 599
+ L Q L R+ WT+
Sbjct: 418 NMSLGQRLKEPRVEFWTS 435
>AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 525
Score = 123 bits (296), Expect = 4e-27
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 11/235 (4%)
Query: 628 RVKCPQLDIGDENCLVINIFTP---EVSNNLPVLVHVHGGDYQNGWG-FHQPPINLINKG 683
+V P+ + E+CL +NI+ P + + LPVLV GG ++ G +
Sbjct: 109 KVHYPKFGVS-EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYED 167
Query: 684 IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEA 743
+++V YR+G+ GF APGN KDQVAAL W+Q+NI+ FGGDP+ VT++G A
Sbjct: 168 VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 227
Query: 744 GSISIQLLLQARLMMG-FHKVILESGSILSP--TALTYNPIADAFAIGEQLGYNDTNNSH 800
G+IS+ L+ + + G FHK I+ESG + P A Y D + G N+ ++S
Sbjct: 228 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCG-NNASDSE 286
Query: 801 KLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
LL+ LR LL + + V+ A +PL LL IP ++
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTKSFTRVVDGA--FFPNEPLDLLSQKAFKAIPSII 339
Score = 90.2 bits (214), Expect = 3e-17
Identities = 53/143 (37%), Positives = 76/143 (53%), Gaps = 5/143 (3%)
Query: 180 SQDCLTLSIFAPTNAENVS---VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+AP +A+ S VL F GSA G + +++V+ YR
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS-IFDGSALAAYEDVLVVVVQYR 176
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + APGN A KD AL W++ NI FGG+P ++ + GE + L
Sbjct: 177 LGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLI 236
Query: 297 LSSSSRNYFDKAITESG-SVLSY 318
LS ++ F KAI ESG +++ Y
Sbjct: 237 LSPMAKGLFHKAIMESGVAIIPY 259
Score = 35.1 bits (77), Expect = 1.3
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
Query: 532 EGTAEREVV--DIMVDTWFTFIENGNPVANETD-WNRLTVTVPAQEEWMQLGPEIGLKQG 588
EG E E + M+ W TF GNP N+ W +T E+++QL + L Q
Sbjct: 425 EGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT----EQYLQLDLNMSLGQR 480
Query: 589 LHLSRLNLWTN 599
L R++ WT+
Sbjct: 481 LKEPRVDFWTS 491
>BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein.
Length = 823
Score = 120 bits (290), Expect = 2e-26
Identities = 125/442 (28%), Positives = 194/442 (43%), Gaps = 67/442 (15%)
Query: 113 LIETTHGLVRGFEWHTT----GDIISYIDIPYAKYT---KYFEEPKSSNAWETTHEVREH 165
L+ T G +RG + G +I ++ +PYA + F+ P+ + W +
Sbjct: 54 LVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQF 113
Query: 166 KSRCPQ--LQGE--------------SVVGS------QDCLTLSIFAPTNAE------NV 197
CPQ + G VV S +DCL L+I+ PT +
Sbjct: 114 APVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPK 173
Query: 198 SVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAAL 256
V+ +IH ++++G+ + LY L S G ++V+ NYRLG LGFL + A GN L
Sbjct: 174 PVMVYIHGGSYMEGTGN--LYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGL 231
Query: 257 KDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLAL---------SSSSRNYFDK 307
DL AL+W NI FGG+P I V G G G+ + L L S+S++ F +
Sbjct: 232 LDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQR 291
Query: 308 AITESGSVLSYWALDRNPALTGEKL-TEALTKIDNSLNL----------ETADILTILRA 356
AI +SG+ LS WA+ PA L T+ + +++ L E D I A
Sbjct: 292 AIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVD-QDIQPA 350
Query: 357 AQNIHFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIE 413
+I F P I+ + P ++ + E +N M+G GL E + ++ I
Sbjct: 351 RYHIAFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGIS 407
Query: 414 QLNDDFATLLPDDLAFGSDIERQNVVR-NVRSQYFIENKPITLEDHIEGLSLCFTDSCFL 472
+ DFA D +G E ++V+R ++ Y E + L FTD ++
Sbjct: 408 ASDFDFAVSNFVDNLYGYP-EGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWV 466
Query: 473 GPAIRTARSLANAGAKVYFYEF 494
PA+ TA +N G+ YFY F
Sbjct: 467 APAVATADLHSNFGSPTYFYAF 488
Score = 112 bits (270), Expect = 6e-24
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 18/195 (9%)
Query: 639 ENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNY 691
E+CL +NI+ P + PV+V++HGG Y G G L + G +I++T NY
Sbjct: 151 EDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNY 210
Query: 692 RIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLL 751
R+GVLGFL G AA GN GL D + AL W +NI FGGDP +T++G+ AG + LL
Sbjct: 211 RLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLL 270
Query: 752 LQARLMMG----------FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHK 801
+ G F + I +SG+ LS A+++ P A + ++G N +++ +
Sbjct: 271 TLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCN-VSDTVE 329
Query: 802 LLKYLRKLSVTVLLD 816
L++ L+K L+D
Sbjct: 330 LVECLQKKPYKELVD 344
>AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein.
Length = 826
Score = 120 bits (290), Expect = 2e-26
Identities = 125/442 (28%), Positives = 194/442 (43%), Gaps = 67/442 (15%)
Query: 113 LIETTHGLVRGFEWHTT----GDIISYIDIPYAKYT---KYFEEPKSSNAWETTHEVREH 165
L+ T G +RG + G +I ++ +PYA + F+ P+ + W +
Sbjct: 57 LVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQF 116
Query: 166 KSRCPQ--LQGE--------------SVVGS------QDCLTLSIFAPTNAE------NV 197
CPQ + G VV S +DCL L+I+ PT +
Sbjct: 117 APVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPK 176
Query: 198 SVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAAL 256
V+ +IH ++++G+ + LY L S G ++V+ NYRLG LGFL + A GN L
Sbjct: 177 PVMVYIHGGSYMEGTGN--LYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGL 234
Query: 257 KDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLAL---------SSSSRNYFDK 307
DL AL+W NI FGG+P I V G G G+ + L L S+S++ F +
Sbjct: 235 LDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQR 294
Query: 308 AITESGSVLSYWALDRNPALTGEKL-TEALTKIDNSLNL----------ETADILTILRA 356
AI +SG+ LS WA+ PA L T+ + +++ L E D I A
Sbjct: 295 AIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVD-QDIQPA 353
Query: 357 AQNIHFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIE 413
+I F P I+ + P ++ + E +N M+G GL E + ++ I
Sbjct: 354 RYHIAFGPVID---GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGIS 410
Query: 414 QLNDDFATLLPDDLAFGSDIERQNVVR-NVRSQYFIENKPITLEDHIEGLSLCFTDSCFL 472
+ DFA D +G E ++V+R ++ Y E + L FTD ++
Sbjct: 411 ASDFDFAVSNFVDNLYGYP-EGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWV 469
Query: 473 GPAIRTARSLANAGAKVYFYEF 494
PA+ TA +N G+ YFY F
Sbjct: 470 APAVATADLHSNFGSPTYFYAF 491
Score = 112 bits (270), Expect = 6e-24
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 18/195 (9%)
Query: 639 ENCLVINIFTP------EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNY 691
E+CL +NI+ P + PV+V++HGG Y G G L + G +I++T NY
Sbjct: 154 EDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNY 213
Query: 692 RIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLL 751
R+GVLGFL G AA GN GL D + AL W +NI FGGDP +T++G+ AG + LL
Sbjct: 214 RLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLL 273
Query: 752 LQARLMMG----------FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHK 801
+ G F + I +SG+ LS A+++ P A + ++G N +++ +
Sbjct: 274 TLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCN-VSDTVE 332
Query: 802 LLKYLRKLSVTVLLD 816
L++ L+K L+D
Sbjct: 333 LVECLQKKPYKELVD 347
>AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein.
Length = 835
Score = 120 bits (289), Expect = 3e-26
Identities = 108/377 (28%), Positives = 170/377 (45%), Gaps = 39/377 (10%)
Query: 656 PVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV++ +HGG Y G G + +I+ T NYR+GVLGFL G AA GN GL D
Sbjct: 178 PVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLD 237
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ AG+ + LL+ + G F K I +SG+ +S
Sbjct: 238 QIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISS 297
Query: 774 TALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDA-------HKISLPCVE 826
++ Y P+ + ++G D +S + ++ LR+ L+D H P V+
Sbjct: 298 WSVNYQPLKYTRLLAAKVGC-DREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVD 356
Query: 827 SVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTR---LK-LRHNSEKLKTVPEDFVDLLPS 882
++ DP L++ G N ML+ + LK + ++E V D S
Sbjct: 357 G-----DVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVS 411
Query: 883 NLEFTNDGI---RYKISELIKDFYF-FKDIDTSSSYENYL----NDVLMVYPTVKYAVL- 933
N G + + E IK Y + D D L D V P V A L
Sbjct: 412 NFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLH 471
Query: 934 --YATKNYFNVYLMNFNYEADADVLSEQNKKLVDFIF-----GENDL---NYNKNNEAIQ 983
Y + YF + + E + + + ++F G DL N++KN+ +
Sbjct: 472 ADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLS 531
Query: 984 KLT-NLFSNFIKLGDPS 999
+ ++NF K GDP+
Sbjct: 532 AVVMTYWTNFAKTGDPN 548
Score = 106 bits (255), Expect = 4e-22
Identities = 88/312 (28%), Positives = 145/312 (46%), Gaps = 23/312 (7%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +H ++++G+ + ++ L + G ++V NYRLG LGFL + A GN L
Sbjct: 179 VMLFLHGGSYMEGTGN--MFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLL 236
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P+ I + G G + + L LS S F KAI +SG+ +S
Sbjct: 237 DQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAIS 296
Query: 318 YWALDRNPALTGEKLTEALTKIDNSLNLETADIL-----------TILRAAQNIHFRPCI 366
W+++ P L +L A D + E + L + A +I F P +
Sbjct: 297 SWSVNYQP-LKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVV 355
Query: 367 EKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLNEALD--QNEASIEQLNDDFATLL 423
+ + P ++++ E +N +IG GL D ++E + DF
Sbjct: 356 D---GDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSN 412
Query: 424 PDDLAFGSDIERQNVVR-NVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSL 482
D +G E ++V+R ++ Y E + L FTD ++ PA+ TA+
Sbjct: 413 FVDNLYGYP-EGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLH 471
Query: 483 ANAGAKVYFYEF 494
A+ + VYFY F
Sbjct: 472 ADYQSPVYFYTF 483
>BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein
protein.
Length = 351
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 64 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 123
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 124 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 183
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 184 WAVNYQPVEYTSLLADKVGCN 204
Score = 97.1 bits (231), Expect = 3e-19
Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 7/158 (4%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 65 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 122
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 123 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 182
Query: 318 YWALDRNPALTGEKLTEALTKIDNSLNLETADILTILR 355
WA++ P + T L L+T D++ LR
Sbjct: 183 SWAVNYQPV----EYTSLLADKVGCNVLDTVDMVDCLR 216
>BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein.
Length = 454
Score = 120 bits (288), Expect = 4e-26
Identities = 87/264 (32%), Positives = 138/264 (52%), Gaps = 25/264 (9%)
Query: 639 ENCLVINIFTPEVSNN---LPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +N++ P + LPV+V GG + G +L + +++V +R+G
Sbjct: 77 EDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLG 136
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GFL A GN GL DQ+AAL W+Q+NI FGGDP +VTL+G AG++SI L+ +
Sbjct: 137 IFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMS 196
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVT- 812
L G FH+ I +SG+ L +T NP+ A + G N N++ L+ LR LS T
Sbjct: 197 PLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNH-NSTQILVNCLRALSGTK 255
Query: 813 VLLDAHKISLPCVESVNNAESL------------IDKDPLQLLKDGPIDNIPMLVSYTRL 860
V+ ++K+ + + E + I DPL LL G + ++P L+ L
Sbjct: 256 VMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNL 315
Query: 861 K----LRHN--SEKLKTVPEDFVD 878
+ L +N E++ V E+++D
Sbjct: 316 EFNWLLPYNITKEQVPLVVEEYLD 339
Score = 86.6 bits (205), Expect = 4e-16
Identities = 49/156 (31%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Query: 180 SQDCLTLSIFAPTNAEN---VSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+++AP A + V+ F+ G+A + G + + ++LV +R
Sbjct: 76 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREKVVLVFLQHR 134
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GFL ++ A GN L D AL+W++ NIA FGG+P + + G+ I L
Sbjct: 135 LGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLM 194
Query: 297 LSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKL 332
+S + F +AI++SG+ L + NP +K+
Sbjct: 195 MSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKV 230
>BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein.
Length = 828
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 301 WAVNYQPVKYTSLLADKVGCN 321
Score = 107 bits (258), Expect = 2e-22
Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 182 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 239
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 240 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 299
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 300 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 359
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 360 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 416
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 417 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 476
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 477 YGSPTYFYAF 486
>AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo
protein.
Length = 545
Score = 120 bits (288), Expect = 4e-26
Identities = 87/264 (32%), Positives = 138/264 (52%), Gaps = 25/264 (9%)
Query: 639 ENCLVINIFTPEVSNN---LPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +N++ P + LPV+V GG + G +L + +++V +R+G
Sbjct: 218 EDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLG 277
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GFL A GN GL DQ+AAL W+Q+NI FGGDP +VTL+G AG++SI L+ +
Sbjct: 278 IFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMS 337
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVT- 812
L G FH+ I +SG+ L +T NP+ A + G N N++ L+ LR LS T
Sbjct: 338 PLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNH-NSTQILVNCLRALSGTK 396
Query: 813 VLLDAHKISLPCVESVNNAESL------------IDKDPLQLLKDGPIDNIPMLVSYTRL 860
V+ ++K+ + + E + I DPL LL G + ++P L+ L
Sbjct: 397 VMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNL 456
Query: 861 K----LRHN--SEKLKTVPEDFVD 878
+ L +N E++ V E+++D
Sbjct: 457 EFNWLLPYNITKEQVPLVVEEYLD 480
Score = 86.6 bits (205), Expect = 4e-16
Identities = 49/156 (31%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Query: 180 SQDCLTLSIFAPTNAEN---VSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+++AP A + V+ F+ G+A + G + + ++LV +R
Sbjct: 217 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREKVVLVFLQHR 275
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GFL ++ A GN L D AL+W++ NIA FGG+P + + G+ I L
Sbjct: 276 LGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLM 335
Query: 297 LSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKL 332
+S + F +AI++SG+ L + NP +K+
Sbjct: 336 MSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKV 371
>AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform
protein.
Length = 828
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 301 WAVNYQPVKYTSLLADKVGCN 321
Score = 107 bits (258), Expect = 2e-22
Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 182 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 239
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 240 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 299
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 300 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 359
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 360 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 416
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 417 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 476
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 477 YGSPTYFYAF 486
>AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform
protein.
Length = 848
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 321 WAVNYQPVKYTSLLADKVGCN 341
Score = 107 bits (258), Expect = 2e-22
Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 202 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 259
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 260 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 319
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 320 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 379
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 380 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 436
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 437 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 496
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 497 YGSPTYFYAF 506
>AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HNL3s
protein.
Length = 558
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 321 WAVNYQPVKYTSLLADKVGCN 341
Score = 107 bits (258), Expect = 2e-22
Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 202 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 259
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 260 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 319
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 320 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 379
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 380 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 436
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 437 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 496
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 497 YGSPTYFYAF 506
>AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein.
Length = 682
Score = 120 bits (288), Expect = 4e-26
Identities = 59/141 (41%), Positives = 86/141 (60%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G L + G +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 35 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 94
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 95 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 154
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 155 WAVNYQPVKYTSLLADKVGCN 175
Score = 107 bits (258), Expect = 2e-22
Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + L S G ++V+ NYR+G LGFL + A GN L
Sbjct: 36 VMVYIHGGSYMEGTGN--MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 93
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 94 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 153
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 154 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 213
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 214 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 270
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 271 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 330
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 331 YGSPTYFYAF 340
>BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein.
Length = 568
Score = 119 bits (286), Expect = 6e-26
Identities = 77/222 (34%), Positives = 122/222 (54%), Gaps = 7/222 (3%)
Query: 639 ENCLVINIFTP-EV--SNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIG 694
E+CLV+N+++P EV + PV+V VHGG G L G +++VT YR+G
Sbjct: 122 EDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLG 181
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
VLGF G APGN G D VAAL W+Q+NI FGGD N VT++G AG I L+ +
Sbjct: 182 VLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLS 241
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTV 813
+ G FH+ I +SG I +P + +P A I L + ++ + ++++ L++
Sbjct: 242 PVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPA-EMVQCLQQKEGEE 300
Query: 814 LLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
L+ + K+ + + ++ K P +LLK+ P ++P L+
Sbjct: 301 LVLSKKLK-NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLM 341
Score = 105 bits (252), Expect = 8e-22
Identities = 114/483 (23%), Positives = 207/483 (42%), Gaps = 52/483 (10%)
Query: 114 IETTHGLVRGFEWHTTGD---IISYIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKS 167
++TT G VRG + G + ++ IP+A+ F P + WE +
Sbjct: 36 VDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPP 95
Query: 168 RCPQ-----------LQGESVVGS--QDCLTLSIFAPTNAENVS---VLFHIHESNFVQG 211
C Q L G+ + S +DCL L++++P S V+ +H + G
Sbjct: 96 MCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITG 155
Query: 212 SADPALYGPEYLVSKG-LILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNI 270
+A Y L + G +++V YRLG LGF + APGN D+ AL+W++ NI
Sbjct: 156 AATS--YDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENI 213
Query: 271 AKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALDRNPALTGE 330
A FGG+ + + V G G++I L LS + F +AIT+SG + + +D +P +
Sbjct: 214 APFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQ 273
Query: 331 KLTEALTKIDNS-------LNLETADILTILRAAQNIHFRPCIEKGNNPFMTQTPWGMIR 383
K+ L +S L + + L + + +N + P G ++P +++
Sbjct: 274 KIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIY-PLTVDGT--VFPKSPKELLK 330
Query: 384 EQEV-NITFMIGSANYAGLNEALDQNEA---SIEQLNDDFATLLPDDLAFGSDIERQNVV 439
E+ ++ F++G N+ + + + ++EQ++ + + + D+ + ++
Sbjct: 331 EKPFHSVPFLMGVNNHE-FSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPE-MM 388
Query: 440 RNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLANAGAKVYFYEF----- 494
V +Y N + + D P + +R L ++G+ V+FYEF
Sbjct: 389 PTVIDEYLGSNS--DAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPS 446
Query: 495 SFTELISESHTVDRPVEGAVRGDIRNYVFTQDGRILTEGTAEREVVDI-MVDTWFTFIEN 553
SF ++ D EGA + F D E T E + + + M+ W F
Sbjct: 447 SFAKIKPAWVKADHGAEGAF---VFGGPFLMDESSRLEATEEEKQLSLTMMAQWTHFART 503
Query: 554 GNP 556
G+P
Sbjct: 504 GDP 506
>AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo
protein.
Length = 571
Score = 119 bits (286), Expect = 6e-26
Identities = 77/222 (34%), Positives = 122/222 (54%), Gaps = 7/222 (3%)
Query: 639 ENCLVINIFTP-EV--SNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIG 694
E+CLV+N+++P EV + PV+V VHGG G L G +++VT YR+G
Sbjct: 122 EDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLG 181
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
VLGF G APGN G D VAAL W+Q+NI FGGD N VT++G AG I L+ +
Sbjct: 182 VLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLS 241
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTV 813
+ G FH+ I +SG I +P + +P A I L + ++ + ++++ L++
Sbjct: 242 PVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPA-EMVQCLQQKEGEE 300
Query: 814 LLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
L+ + K+ + + ++ K P +LLK+ P ++P L+
Sbjct: 301 LVLSKKLK-NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLM 341
Score = 104 bits (250), Expect = 1e-21
Identities = 115/485 (23%), Positives = 211/485 (43%), Gaps = 53/485 (10%)
Query: 114 IETTHGLVRGFEWHTTGD---IISYIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKS 167
++TT G VRG + G + ++ IP+A+ F P + WE +
Sbjct: 36 VDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPP 95
Query: 168 RCPQ-----------LQGESVVGS--QDCLTLSIFAPTNAENVS---VLFHIHESNFVQG 211
C Q L G+ + S +DCL L++++P S V+ +H + G
Sbjct: 96 MCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITG 155
Query: 212 SADPALYGPEYLVSKG-LILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNI 270
+A Y L + G +++V YRLG LGF + APGN D+ AL+W++ NI
Sbjct: 156 AATS--YDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENI 213
Query: 271 AKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALDRNPALTGE 330
A FGG+ + + V G G++I L LS + F +AIT+SG + + +D +P +
Sbjct: 214 APFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQ 273
Query: 331 KLTEALTKIDNS-------LNLETADILTILRAAQNIHFRPCIEKGNNPFMTQTPWGMIR 383
K+ L +S L + + L + + +N + P G ++P +++
Sbjct: 274 KIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIY-PLTVDGT--VFPKSPKELLK 330
Query: 384 EQEV-NITFMIGSANYAGLNEALDQNEA---SIEQLNDDFATLLPDDLAFGSDIERQNVV 439
E+ ++ F++G N+ + + + ++EQ++ + + + D+ + ++
Sbjct: 331 EKPFHSVPFLMGVNNHE-FSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPE-MM 388
Query: 440 RNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLANAGAKVYFYEF----- 494
V +Y N + + D P + +R L ++G+ V+FYEF
Sbjct: 389 PTVIDEYLGSNS--DAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPS 446
Query: 495 SFTELISESHTVDRPVEGA-VRGDIRNYVFTQDGRI-LTEGTAEREVVDI-MVDTWFTFI 551
SF ++ D EGA V G ++ + R+ E T E + + + M+ W F
Sbjct: 447 SFAKIKPAWVKADHGAEGAFVFGG--PFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFA 504
Query: 552 ENGNP 556
G+P
Sbjct: 505 RTGDP 509
>AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HNL3
protein.
Length = 828
Score = 118 bits (285), Expect = 8e-26
Identities = 58/141 (41%), Positives = 84/141 (59%), Gaps = 2/141 (1%)
Query: 656 PVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
PV+V++HGG Y G G I +I++T NYR+GVLGFL G AA GN GL D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSP 773
Q+ AL W+ +NI FGGDP +T++G+ G+ + LL + G F + I++SGS LS
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300
Query: 774 TALTYNPIADAFAIGEQLGYN 794
A+ Y P+ + +++G N
Sbjct: 301 WAVNYQPVKYTSLLADKVGCN 321
Score = 105 bits (251), Expect = 1e-21
Identities = 88/310 (28%), Positives = 143/310 (46%), Gaps = 19/310 (6%)
Query: 199 VLFHIHESNFVQGSADPALYGPEYLVSKGLILVLP-NYRLGPLGFLCLRNTMAPGNAALK 257
V+ +IH ++++G+ + + S G ++V+ NYR+G LGFL + A GN L
Sbjct: 182 VMVYIHGGSYMEGTGN--MIDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 239
Query: 258 DLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
D AL+W+ NIA FGG+P I V G G + + L LS S F +AI +SGS LS
Sbjct: 240 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 299
Query: 318 YWALDRNP----ALTGEKL-TEALTKID--NSLNLETADILT---ILRAAQNIHFRPCIE 367
WA++ P +L +K+ L +D + L ++A L I A ++ F P I+
Sbjct: 300 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVID 359
Query: 368 KGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASIEQLNDDFATLLP 424
+ P ++ + E +N M+G GL E + E + + D++
Sbjct: 360 ---GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNF 416
Query: 425 DDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLAN 484
D +G + + ++ Y E + L FTD ++ P++ TA A
Sbjct: 417 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR 476
Query: 485 AGAKVYFYEF 494
G+ YFY F
Sbjct: 477 YGSPTYFYAF 486
>Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein.
Length = 559
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 71 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 130
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 131 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 190
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 191 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 250
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 251 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 307
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 308 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 339
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 33 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 92
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 93 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 152
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 153 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 210
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 211 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 258
>U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein.
Length = 550
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 62 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 121
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 122 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 181
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 182 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 241
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 242 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 298
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 299 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 330
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 24 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 83
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 84 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 143
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 144 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 201
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 202 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 249
>D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precursor
protein.
Length = 559
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 71 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 130
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 131 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 190
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 191 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 250
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 251 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 307
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 308 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 339
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 33 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 92
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 93 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 152
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 153 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 210
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 211 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 258
>BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein.
Length = 587
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 115 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 174
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 175 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 234
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 235 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 294
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 295 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 351
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 352 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 383
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 77 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 136
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 137 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 196
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 197 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 254
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 255 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 302
>BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein.
Length = 586
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 114 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 173
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 174 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 233
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 234 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 293
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 294 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 350
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 351 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 382
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 76 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 135
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 136 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 195
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 196 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 253
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 254 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 301
>BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 135 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 194
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 195 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 254
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 255 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 314
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 315 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 371
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 372 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 403
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 97 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 157 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 216
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 217 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 274
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 275 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 322
>AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 135 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 194
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 195 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 254
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 255 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 314
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 315 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 371
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 372 KMIPGVVDG-VFLPRHPQELLASADFQPVPSIV 403
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 97 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 157 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 216
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 217 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 274
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 275 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 322
>AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isoform
1 variant protein.
Length = 582
Score = 118 bits (284), Expect = 1e-25
Identities = 89/273 (32%), Positives = 131/273 (47%), Gaps = 29/273 (10%)
Query: 608 MRNNAPKPPPRWDGVFEAT-HRVKCPQ------------------LDIGDENCLVINIFT 648
+R P+PP W GV + T H C Q D E+CL ++I+T
Sbjct: 94 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 153
Query: 649 PEVSN---NLPVLVHVHGGDYQNGWG-FHQPPINLINKGIIIVTFNYRIGVLGFLCLGIP 704
P S+ NLPV+V +HGG G + + + +++V YR+GVLGF G
Sbjct: 154 PAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDK 213
Query: 705 AAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKV 763
A GN G DQVAAL W+QQNI FGG+P+ VT++G AG S+ L+ + + G FH
Sbjct: 214 HATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGA 273
Query: 764 ILESGSILSPTALTYNPIADAFA-IGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISL 822
I+ESG L P + + AD + + L D +S L+ LR S +L +K
Sbjct: 274 IMESGVALLPGLIASS--ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK-PF 330
Query: 823 PCVESVNNAESLIDKDPLQLLKDGPIDNIPMLV 855
+ V + + + P +LL +P +V
Sbjct: 331 KMIPGVVDG-VFLPRHPKELLASADFQPVPSIV 362
Score = 99.5 bits (237), Expect = 6e-20
Identities = 76/228 (33%), Positives = 109/228 (47%), Gaps = 27/228 (11%)
Query: 114 IETTH-GLVRGFEWHTTG---DIISYIDIPYAKYTK---YFEEPKSSNAWETTHEVREHK 166
I TTH G V G H G + +++ IP+AK F P+ +W + H
Sbjct: 56 IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 115
Query: 167 SRCPQ----LQGE----------SVVGSQDCLTLSIFAPTNAE---NVSVLFHIHESNFV 209
+ C Q ++ E S S+DCL LSI+ P ++ N+ V+ IH V
Sbjct: 116 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALV 175
Query: 210 QGSADPALYGPEYLVS-KGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKN 268
G A +LY L + + +++V+ YRLG LGF + A GN D AL+W++
Sbjct: 176 FGMA--SLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQ 233
Query: 269 NIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVL 316
NIA FGGNPD + + GE G + L +S S+ F AI ESG L
Sbjct: 234 NIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 281
>AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-related
protein protein.
Length = 288
Score = 112 bits (269), Expect = 7e-24
Identities = 59/158 (37%), Positives = 89/158 (56%), Gaps = 5/158 (3%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 116 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 175
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G +PGN G DQ+AAL+W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 176 IWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLS 235
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQL 791
L FH+ I ESG L+ + + +G +L
Sbjct: 236 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEVGLRL 273
Score = 89.8 bits (213), Expect = 4e-17
Identities = 49/141 (34%), Positives = 74/141 (52%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 115 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 173
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + +PGN D AL W+++NIA FGGNP ++ + G G + L
Sbjct: 174 LGIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLV 233
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 234 LSPLAKNLFHRAISESGVALT 254
>BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein.
Length = 442
Score = 111 bits (266), Expect = 2e-23
Identities = 103/379 (27%), Positives = 169/379 (44%), Gaps = 36/379 (9%)
Query: 655 LPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLK 713
LPV+V GG + G +L + +++V +R+G+ GFL A GN GL
Sbjct: 14 LPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLL 73
Query: 714 DQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILS 772
DQ+AAL W+Q+NI FGGDP +VTL+G AG++SI L+ + L G FH+ I +SG+ L
Sbjct: 74 DQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALF 133
Query: 773 PTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVT-VLLDAHKISLPCVESVNNA 831
+T NP+ A + G N N++ L+ LR LS T V+ ++K+ + +
Sbjct: 134 RLFITRNPLKVAKKVAHLAGCNH-NSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDP 192
Query: 832 ESL------------IDKDPLQLLKDGPIDNIPMLVSYTRLKLRHNSEKLKTVP------ 873
E + I DPL LL G + ++P L+ L+ + P
Sbjct: 193 EEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAM 252
Query: 874 --EDFVDLLPSN---LEFTNDGIRYKISELIKDFYFFKDIDTSSSYENYLNDVLMVYPTV 928
E +L S L T + + + E + + + + + D VY T+
Sbjct: 253 RKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATL 312
Query: 929 KYAVLYATKNYFNVYLMNFNYEADADVLSEQNKKL-----VDFIFG---ENDLNYNKNNE 980
+ A Y VYL F + A ++ + + F+FG L+ K
Sbjct: 313 QTA-HYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKA 371
Query: 981 AIQKLTNLFSNFIKLGDPS 999
++ ++NF + G+P+
Sbjct: 372 LSLQMMKYWANFARTGNPN 390
Score = 78.2 bits (184), Expect = 1e-13
Identities = 45/149 (30%), Positives = 76/149 (51%), Gaps = 4/149 (2%)
Query: 187 SIFAPTNAEN---VSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYRLGPLGFL 243
+++AP A + V+ F+ G+A + G + + ++LV +RLG GFL
Sbjct: 1 NVYAPARAPGDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREKVVLVFLQHRLGIFGFL 59
Query: 244 CLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRN 303
++ A GN L D AL+W++ NIA FGG+P + + G+ I L +S +
Sbjct: 60 STDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASG 119
Query: 304 YFDKAITESGSVLSYWALDRNPALTGEKL 332
F +AI++SG+ L + RNP +K+
Sbjct: 120 LFHRAISQSGTALFRLFITRNPLKVAKKV 148
Score = 36.7 bits (81), Expect = 0.44
Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 8/137 (5%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D+ F+ ++TA +AG VY YEF E + V +GA GD ++F
Sbjct: 304 DATFVYATLQTAHYHRDAGLPVYLYEF---EHHARGIIVKPRTDGADHGDEMYFLFGGPF 360
Query: 528 RILTEGTAEREVVDIMVDTWFTFIENGNP-VANETDWNRLTVTVPAQEEWMQLGPEIGLK 586
E+ + M+ W F GNP N W R E+++QL +
Sbjct: 361 ATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYN----KDEKYLQLDFTTRVG 416
Query: 587 QGLHLSRLNLWTNIYNN 603
L ++ W ++Y +
Sbjct: 417 MKLKEKKMAFWMSLYQS 433
>AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase
hBr3 protein.
Length = 567
Score = 110 bits (265), Expect = 2e-23
Identities = 72/200 (36%), Positives = 110/200 (55%), Gaps = 11/200 (5%)
Query: 639 ENCLVINIFTP-EVSNN--LPVLVHVHGGDYQNGWGFHQPPINL-INKGIIIVTFNYRIG 694
E+CL +NI+TP +++ N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTALT--YNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSV 811
L FH+ I ESG L+ +T PIA A L T S ++ LR+ +
Sbjct: 234 PLAKNLFHRAISESGVSLTAALITTDVKPIAGLVA---TLSGCKTTTSAVMVHCLRQKTE 290
Query: 812 TVLLDAH-KISLPCVESVNN 830
LL+ K++L ++ + N
Sbjct: 291 DELLETSLKLNLFKLDLLGN 310
Score = 88.2 bits (209), Expect = 1e-16
Identities = 50/141 (35%), Positives = 74/141 (52%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH V G A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGAS-TYDGLALSAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVSLT 252
Score = 46.0 bits (104), Expect = 7e-04
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ +RS +AGA Y YEF + H + AV GD + +F+ G
Sbjct: 421 DVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSRHEDPK----AVIGDHGDEIFSVFG 476
Query: 528 R-ILTEGTAERE--VVDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L +G +E E + +++ W F NGNP W R + +E ++++G
Sbjct: 477 SPFLKDGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPR---NMTKKEGYLKIGAST 533
Query: 584 GLKQGLHLSRLNLWTNI 600
Q L ++ W +
Sbjct: 534 QAAQRLKDKEVSFWAEL 550
>X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage
serine-esterase 1 protein.
Length = 503
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 51 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 110
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 111 IWGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 170
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 171 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 207
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 50 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 108
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 109 LGIWGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 168
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 169 LSPLAKNLFHRAISESGVALT 189
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 359 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 413
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 414 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 469
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 470 QAAQKLKDKEVAFWTNLFAKKAVE 493
>S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholesterol
acyltransferase protein.
Length = 568
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 115 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 174
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 175 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 234
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 235 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 271
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 114 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 172
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 173 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 232
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 233 LSPLAKNLFHRAISESGVALT 253
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 424 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 478
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 479 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 534
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 535 QAAQKLKDKEVAFWTNLFAKKAVE 558
>M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein.
Length = 454
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 1 EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 60
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 61 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 120
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 121 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 157
Score = 85.0 bits (201), Expect = 1e-15
Identities = 47/140 (33%), Positives = 73/140 (52%), Gaps = 4/140 (2%)
Query: 181 QDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYRL 237
+ CL L+I+ P T + V+ IH + G+A G + +++V YRL
Sbjct: 1 EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYRL 59
Query: 238 GPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLAL 297
G GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L L
Sbjct: 60 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 119
Query: 298 SSSSRNYFDKAITESGSVLS 317
S ++N F +AI+ESG L+
Sbjct: 120 SPLAKNLFHRAISESGVALT 139
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 310 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 364
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 365 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGKGLPHWPEYN----QKEGYLQIGANT 420
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 421 QAAQKLKDKEVAFWTNLFAKKAVE 444
>M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein.
Length = 507
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 54 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 113
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 114 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 173
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 174 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 210
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 53 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 111
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 112 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 171
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 172 LSPLAKNLFHRAISESGVALT 192
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 363 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 417
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 418 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 473
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 474 QAAQKLKDKEVAFWTNLFAKKAVE 497
>L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein.
Length = 566
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 46.8 bits (106), Expect = 4e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 422 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 476
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 477 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 532
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 533 QAGQKLKDKEVAFWTNLFAKKAVE 556
>L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein.
Length = 568
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 115 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 174
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 175 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 234
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 235 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 271
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 114 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 172
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 173 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 232
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 233 LSPLAKNLFHRAISESGVALT 253
Score = 46.8 bits (106), Expect = 4e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 424 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 478
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 479 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 534
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 535 QAGQKLKDKEVAFWTNLFAKKAVE 558
>D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 566
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 422 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 476
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 477 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 532
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 533 QAAQKLKDKEVAFWTNLFAKKAVE 556
>AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester
hydrolase protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR+ +AGA Y YEF + S +P V GD + +F+ G
Sbjct: 423 DVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDM---KP--KTVIGDHGDELFSVFG 477
Query: 528 R-ILTEGTAEREV--VDIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
L EG +E E+ +++ W F NGNP W +E ++Q+G
Sbjct: 478 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN----QKEGYLQIGANT 533
Query: 584 GLKQGLHLSRLNLWTNIYNNYFIE 607
Q L + WTN++ +E
Sbjct: 534 QAAQKLKDKEVAFWTNLFAKKAVE 557
>AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase
hBr1 protein.
Length = 429
Score = 109 bits (261), Expect = 7e-23
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 8/157 (5%)
Query: 639 ENCLVINIFTPE---VSNNLPVLVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIG 694
E+CL +NI+TP N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G + GN G DQVAAL W+Q NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTAL---TYNPIADAFAI 787
L FH+ I ESG L+ + P+A+ AI
Sbjct: 234 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 270
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/141 (34%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH + G+A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + + GN D AL+W+++NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
>M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase
protein.
Length = 614
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase,
isoform E4-E5 precursor protein.
Length = 617
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Yt
blood group) protein.
Length = 617
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein.
Length = 546
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (YT
blood group) protein.
Length = 617
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase
isoform E4-E6 precursor variant protein.
Length = 614
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related
acetylcholinesterase protein.
Length = 526
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein.
Length = 617
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein.
Length = 614
Score = 107 bits (258), Expect = 2e-22
Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PVLV ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 106 bits (254), Expect = 5e-22
Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P VL I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein.
Length = 640
Score = 107 bits (256), Expect = 3e-22
Identities = 57/144 (39%), Positives = 87/144 (60%), Gaps = 7/144 (4%)
Query: 639 ENCLVINIFTP--EVSNNLPVLVHVHGGDYQNGWG---FHQPPINLINKGIIIVTFNYRI 693
E+CL +N++TP ++ PV+V ++GG + +G + + + ++V+ NYR+
Sbjct: 125 EDCLYLNVWTPYPRPTSPTPVIVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRV 184
Query: 694 GVLGFLCL-GIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLL 752
G GFL L G APGNVGL DQ AL W+Q+N+ FGGDP VTL+G AG+ S+ + L
Sbjct: 185 GAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHL 244
Query: 753 QARLMMG-FHKVILESGSILSPTA 775
+ G FH+ +L+SG+ P A
Sbjct: 245 LSPPSRGLFHRAVLQSGAPNGPWA 268
Score = 105 bits (252), Expect = 8e-22
Identities = 70/229 (30%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 113 LIETTHGLVRGFEWHTTGDIIS-YIDIPYAKYT---KYFEEPKSSNAWETTHEVREHKSR 168
L+ G +RG T G +S ++ IP+A+ + F P+ W + +S
Sbjct: 40 LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSV 99
Query: 169 C--------PQLQGESVVG-----SQDCLTLSIFAP--TNAENVSVLFHIHESNFVQGSA 213
C P +G + S+DCL L+++ P V+ I+ F G++
Sbjct: 100 CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVIVWIYGGGFYSGAS 159
Query: 214 DPALYGPEYLV-SKGLILVLPNYRLGPLGFLCLRNTM-APGNAALKDLSMALQWIKNNIA 271
+Y +LV ++ +LV NYR+G GFL L + APGN L D +ALQW++ N+A
Sbjct: 160 SLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVA 219
Query: 272 KFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWA 320
FGG+P ++ + GE A +G LS SR F +A+ +SG+ WA
Sbjct: 220 AFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
>AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase
hBr2 protein.
Length = 565
Score = 106 bits (254), Expect = 5e-22
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 6/183 (3%)
Query: 639 ENCLVINIFTP-EVSNN--LPVLVHVHGGDYQNGWGFHQPPINL-INKGIIIVTFNYRIG 694
E+CL +NI+TP +++ N LPV+V +HGG G + L ++ +++VT YR+G
Sbjct: 114 EDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLG 173
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQA 754
+ GF G GN G DQ+AAL W+Q+NI FGG+P VT++G AG S+ +L+ +
Sbjct: 174 IWGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGESAGGESVSVLVLS 233
Query: 755 RLMMG-FHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTV 813
L FH+ I ESG L+ + + A I G T S L+ LR+ +
Sbjct: 234 PLAKNLFHRAISESGVALTAALVKKDMKDTAQQIAVFAGCKST-TSAVLVHCLRQKTEDE 292
Query: 814 LLD 816
LL+
Sbjct: 293 LLE 295
Score = 88.6 bits (210), Expect = 1e-16
Identities = 50/141 (35%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 180 SQDCLTLSIFAP---TNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYR 236
S+DCL L+I+ P T + V+ IH V G A G + +++V YR
Sbjct: 113 SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGAS-TYDGLALSAHENVVVVTIQYR 171
Query: 237 LGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLA 296
LG GF + GN D AL+W++ NIA FGGNP ++ + GE G + L
Sbjct: 172 LGIWGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGESAGGESVSVLV 231
Query: 297 LSSSSRNYFDKAITESGSVLS 317
LS ++N F +AI+ESG L+
Sbjct: 232 LSPLAKNLFHRAISESGVALT 252
Score = 41.9 bits (94), Expect = 0.012
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 13/137 (9%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D F P++ AR +AGA Y YEF + S + D + V GD + +F+ G
Sbjct: 421 DVVFGVPSVTVARHHRDAGAPTYMYEFQY----HPSFSSDMKPQTVV-GDHGDELFSVFG 475
Query: 528 RILTEGTAEREVV---DIMVDTWFTFIENGNPVANE-TDWNRLTVTVPAQEEWMQLGPEI 583
+G A E + +M+ W F +GNP+ + W +E ++Q+G
Sbjct: 476 APFLKGGASEEEIRLSKMMMKLWANFARSGNPMGKGCSSW----PAYDQKEGYLQIGIPT 531
Query: 584 GLKQGLHLSRLNLWTNI 600
Q L + WT +
Sbjct: 532 QPAQKLKSKEMAFWTEL 548
>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
Length = 2768
Score = 103 bits (248), Expect = 3e-21
Identities = 116/435 (26%), Positives = 193/435 (44%), Gaps = 47/435 (10%)
Query: 607 EMRNNAPKPPPRWDGVFEATH-RVKCPQLDIG-------DENCLVINIFTPE-VSNNLPV 657
E R AP+P W G ++A+ R C Q E+CL +N+F P+ V+ N V
Sbjct: 2240 ERRFQAPEPL-NWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASV 2298
Query: 658 LVHVHGG---DYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
LV H + GW +I+VT +YR+GV GFL G GN GL D
Sbjct: 2299 LVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLD 2358
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGS--ISIQLL-LQARLMMGFHKVILESGSIL 771
QVAAL W+Q +I+ FGGDP V+L G+ SI LL +A F + +L GS L
Sbjct: 2359 QVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 2418
Query: 772 SPTALTYNPIA--DAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVN 829
SP A+ + A A A+ +++ ++S +++ LR+ VL DA L +
Sbjct: 2419 SPAAVISHERAQQQAIALAKEVSC-PMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH 2477
Query: 830 NAESLID-----KDPLQLLKDGPIDNIPMLVSYTR----------LKLRHNSEKLKTVPE 874
+ID + P + LK + +L+ ++ +K S+ +
Sbjct: 2478 YWGPVIDGHFLREPPARALKRSLXVEVDLLIGSSQDDGLINRAKAVKQFEESQGRTSSKT 2537
Query: 875 DFVDLLPSNLEFTNDGIRYKISELIKDFYFFKDIDT------SSSYENYLNDVLMVYPTV 928
F L ++L + R E +Y+ + T S + EN D ++ P +
Sbjct: 2538 AFYQALQNSLGGEDSDARV---EAAATWYYSLEHSTDDYASFSRALENATRDYFIICPII 2594
Query: 929 KYAVLYATKNYFNVYLMNF--NY-EADADVLSEQNKKLVDFIFGENDLNYNKNNEAIQ-K 984
A +A + NV++ + NY ++L++ L + + ++ +++ K
Sbjct: 2595 DMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLK 2654
Query: 985 LTNLFSNFIKLGDPS 999
+ FS+FI+ G+P+
Sbjct: 2655 IMQYFSHFIRSGNPN 2669
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 106 PSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAK---YTKYFEEPKSSNAWETTHEV 162
P L+ + + G W + ++ +PYA + F+ P+ N W + +
Sbjct: 2202 PISTHGRLLGRSQAIQVGTSWK---QVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDA 2257
Query: 163 REHKSRC--PQLQGESVVG-SQDCLTLSIFAPTN-AENVSVLFHIHESNFVQGSAD-PAL 217
+ ++ C P + + G S+DCL L++F P N A N SVL H + + S PA+
Sbjct: 2258 SKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAI 2317
Query: 218 YGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNP 277
G LI+V +YR+G GFL + GN L D AL W++ +I FGG+P
Sbjct: 2318 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
Query: 278 DTIVVSGE--GTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
+ ++ + G A I L +++ F +A+ GS LS
Sbjct: 2378 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALS 2419
>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
Length = 1124
Score = 103 bits (246), Expect = 4e-21
Identities = 80/228 (35%), Positives = 114/228 (50%), Gaps = 19/228 (8%)
Query: 607 EMRNNAPKPPPRWDGVFEATH-RVKCPQLDIG-------DENCLVINIFTPE-VSNNLPV 657
E R AP+P W G ++A+ R C Q E+CL +N+F P+ V+ N V
Sbjct: 596 ERRFQAPEPL-NWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASV 654
Query: 658 LVHVHGG---DYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
LV H + GW +I+VT +YR+GV GFL G GN GL D
Sbjct: 655 LVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLD 714
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGS--ISIQLL-LQARLMMGFHKVILESGSIL 771
QVAAL W+Q +I+ FGGDP V+L G+ SI LL +A F + +L GS L
Sbjct: 715 QVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 774
Query: 772 SPTALTYNPIA--DAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDA 817
SP A+ + A A A+ +++ ++S +++ LR+ VL DA
Sbjct: 775 SPAAVISHERAQQQAIALAKEVSC-PMSSSQEVVSCLRQKPANVLNDA 821
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 106 PSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAK---YTKYFEEPKSSNAWETTHEV 162
P L+ + + G W + ++ +PYA + F+ P+ N W + +
Sbjct: 558 PISTHGRLLGRSQAIQVGTSWK---QVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDA 613
Query: 163 REHKSRC--PQLQGESVVG-SQDCLTLSIFAPTN-AENVSVLFHIHESNFVQGSAD-PAL 217
+ ++ C P + + G S+DCL L++F P N A N SVL H + + S PA+
Sbjct: 614 SKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAI 673
Query: 218 YGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNP 277
G LI+V +YR+G GFL + GN L D AL W++ +I FGG+P
Sbjct: 674 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 733
Query: 278 DTIVVSGE--GTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
+ ++ + G A I L +++ F +A+ GS LS
Sbjct: 734 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALS 775
>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
variant protein.
Length = 1574
Score = 103 bits (246), Expect = 4e-21
Identities = 80/228 (35%), Positives = 114/228 (50%), Gaps = 19/228 (8%)
Query: 607 EMRNNAPKPPPRWDGVFEATH-RVKCPQLDIG-------DENCLVINIFTPE-VSNNLPV 657
E R AP+P W G ++A+ R C Q E+CL +N+F P+ V+ N V
Sbjct: 1046 ERRFQAPEPL-NWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASV 1104
Query: 658 LVHVHGG---DYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
LV H + GW +I+VT +YR+GV GFL G GN GL D
Sbjct: 1105 LVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLD 1164
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGS--ISIQLL-LQARLMMGFHKVILESGSIL 771
QVAAL W+Q +I+ FGGDP V+L G+ SI LL +A F + +L GS L
Sbjct: 1165 QVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 1224
Query: 772 SPTALTYNPIA--DAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDA 817
SP A+ + A A A+ +++ ++S +++ LR+ VL DA
Sbjct: 1225 SPAAVISHERAQQQAIALAKEVSC-PMSSSQEVVSCLRQKPANVLNDA 1271
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 106 PSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAK---YTKYFEEPKSSNAWETTHEV 162
P L+ + + G W + ++ +PYA + F+ P+ N W + +
Sbjct: 1008 PISTHGRLLGRSQAIQVGTSWK---QVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDA 1063
Query: 163 REHKSRC--PQLQGESVVG-SQDCLTLSIFAPTN-AENVSVLFHIHESNFVQGSAD-PAL 217
+ ++ C P + + G S+DCL L++F P N A N SVL H + + S PA+
Sbjct: 1064 SKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAI 1123
Query: 218 YGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNP 277
G LI+V +YR+G GFL + GN L D AL W++ +I FGG+P
Sbjct: 1124 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 1183
Query: 278 DTIVVSGE--GTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
+ ++ + G A I L +++ F +A+ GS LS
Sbjct: 1184 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALS 1225
>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
Length = 2767
Score = 101 bits (241), Expect = 2e-20
Identities = 79/228 (34%), Positives = 113/228 (49%), Gaps = 19/228 (8%)
Query: 607 EMRNNAPKPPPRWDGVFEATH-RVKCPQLDIG-------DENCLVINIFTPE-VSNNLPV 657
E AP+P W G ++A+ R C Q E+CL +N+F P+ V+ N V
Sbjct: 2239 ERHFQAPEPL-NWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASV 2297
Query: 658 LVHVHGG---DYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
LV H + GW +I+VT +YR+GV GFL G GN GL D
Sbjct: 2298 LVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLD 2357
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGS--ISIQLL-LQARLMMGFHKVILESGSIL 771
QVAAL W+Q +I+ FGGDP V+L G+ SI LL +A F + +L GS L
Sbjct: 2358 QVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 2417
Query: 772 SPTALTYNPIA--DAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDA 817
SP A+ + A A A+ +++ ++S +++ LR+ VL DA
Sbjct: 2418 SPAAVISHERAQQQAIALAKEVSC-PMSSSQEVVSCLRQKPANVLNDA 2464
Score = 84.2 bits (199), Expect = 2e-15
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 106 PSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAK---YTKYFEEPKSSNAWETTHEV 162
P L+ + + G W + ++ +PYA ++F+ P+ N W + +
Sbjct: 2201 PISTHGRLLGRSQAIQVGTSWK---QVDQFLGVPYAAPPLAERHFQAPEPLN-WTGSWDA 2256
Query: 163 REHKSRC--PQLQGESVVG-SQDCLTLSIFAPTN-AENVSVLFHIHESNFVQGSAD-PAL 217
+ ++ C P + + G S+DCL L++F P N A N SVL H + + S PA+
Sbjct: 2257 SKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAI 2316
Query: 218 YGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNP 277
G LI+V +YR+G GFL + GN L D AL W++ +I FGG+P
Sbjct: 2317 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2376
Query: 278 DTIVVSGE--GTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
+ ++ + G A I L +++ F +A+ GS LS
Sbjct: 2377 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALS 2418
>BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for
IMAGE:40133565) protein.
Length = 422
Score = 98.7 bits (235), Expect = 1e-19
Identities = 73/196 (37%), Positives = 97/196 (49%), Gaps = 16/196 (8%)
Query: 607 EMRNNAPKPPPRWDGVFEATH-RVKCPQLDIG-------DENCLVINIFTPE-VSNNLPV 657
E R AP+P W G ++A+ R C Q E+CL +N+F P+ V+ N V
Sbjct: 202 ERRFQAPEPL-NWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASV 260
Query: 658 LVHVHGG---DYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKD 714
LV H + GW +I+VT +YR+GV GFL G GN GL D
Sbjct: 261 LVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLD 320
Query: 715 QVAALYWIQQNIKRFGGDPNDVTLYGTEAGS--ISIQLL-LQARLMMGFHKVILESGSIL 771
QVAAL W+Q +I+ FGGDP V+L G+ SI LL +A F + +L GS L
Sbjct: 321 QVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 380
Query: 772 SPTALTYNPIADAFAI 787
SP A+ + A AI
Sbjct: 381 SPAAVISHERAQQQAI 396
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 106 PSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAK---YTKYFEEPKSSNAWETTHEV 162
P L+ + + G W + ++ +PYA + F+ P+ N W + +
Sbjct: 164 PISTHGRLLGRSQAIQVGTSWK---QVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDA 219
Query: 163 REHKSRC--PQLQGESVVG-SQDCLTLSIFAPTN-AENVSVLFHIHESNFVQGSAD-PAL 217
+ ++ C P + + G S+DCL L++F P N A N SVL H + + S PA+
Sbjct: 220 SKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAI 279
Query: 218 YGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNP 277
G LI+V +YR+G GFL + GN L D AL W++ +I FGG+P
Sbjct: 280 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 339
Query: 278 DTIVVSGE--GTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
+ ++ + G A I L +++ F +A+ GS LS
Sbjct: 340 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALS 381
>BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein.
Length = 151
Score = 93.9 bits (223), Expect = 3e-18
Identities = 48/136 (35%), Positives = 75/136 (55%), Gaps = 2/136 (1%)
Query: 658 LVHVHGGDYQNGWGFHQPPINLI-NKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQV 716
+V +HGG G + L ++ +++VT YR+G+ GF G +PGN G DQ+
Sbjct: 1 MVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQL 60
Query: 717 AALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSPTA 775
AAL+W+Q NI FGG+P VT++G AG S+ +L+ + L FH+ I ESG L+
Sbjct: 61 AALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 120
Query: 776 LTYNPIADAFAIGEQL 791
+ + +G +L
Sbjct: 121 VKKGDVKPLAEVGLRL 136
Score = 77.4 bits (182), Expect = 3e-13
Identities = 40/115 (34%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Query: 203 IHESNFVQGSADPALYGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMA 262
IH + G+A G + +++V YRLG GF + +PGN D A
Sbjct: 4 IHGGGLMVGAAS-TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAA 62
Query: 263 LQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLS 317
L W+++NIA FGGNP ++ + G G + L LS ++N F +AI+ESG L+
Sbjct: 63 LHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVALT 117
>AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens
cDNA FLJ40219 fis, clone TESTI2021637, moderately
similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
3.1.1.1). ).
Length = 207
Score = 93.1 bits (221), Expect = 5e-18
Identities = 53/125 (42%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Query: 658 LVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQV 716
+V VHGG G L G +++VT YR+GVLGF G APGN G D V
Sbjct: 1 MVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVV 60
Query: 717 AALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSPTA 775
AAL W+Q+NI FGGD N VT++G AG I L+ + + G FH+ I +SG I +P
Sbjct: 61 AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGI 120
Query: 776 LTYNP 780
+ +P
Sbjct: 121 IDSHP 125
Score = 81.8 bits (193), Expect = 1e-14
Identities = 45/135 (33%), Positives = 71/135 (52%), Gaps = 3/135 (2%)
Query: 203 IHESNFVQGSADPALYGPEYLVSKG-LILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSM 261
+H + G+A Y L + G +++V YRLG LGF + APGN D+
Sbjct: 4 VHGGALITGAATS--YDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVA 61
Query: 262 ALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWAL 321
AL+W++ NIA FGG+ + + V G G++I L LS + F +AIT+SG + + +
Sbjct: 62 ALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGII 121
Query: 322 DRNPALTGEKLTEAL 336
D +P +K+ L
Sbjct: 122 DSHPWPLAQKIANTL 136
>AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens
cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
Length = 367
Score = 81.4 bits (192), Expect = 2e-14
Identities = 82/317 (25%), Positives = 138/317 (43%), Gaps = 35/317 (11%)
Query: 716 VAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMG-FHKVILESGSILSPT 774
+AAL W+Q+NI FGGDP +VTL+G AG++SI L+ + L G FH+ I +SG+ L
Sbjct: 1 MAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRP 60
Query: 775 ALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVT-VLLDAHKISLPCVESVNNAES 833
+T NP+ A + G N N++ L+ LR LS T V+ ++K+ + + E
Sbjct: 61 FITSNPLKVAKKVAHLAGCNH-NSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEE 119
Query: 834 L------------IDKDPLQLLKDGPIDNIPMLVSYTRLKLRHNSEKLKTVP-------- 873
+ I DPL LL G + ++P L+ L+ + P
Sbjct: 120 IIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRK 179
Query: 874 EDFVDLLPSN---LEFTNDGIRYKISELIKDFYFFKDIDTSSSYENYLNDVLMVYPTVKY 930
E +L S L T + + + E + + + + + D VY T++
Sbjct: 180 ETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQT 239
Query: 931 AVLYATKNYFNVYLMNFNYEADADVLSEQNKKL-----VDFIFG---ENDLNYNKNNEAI 982
A Y VYL F + A ++ + + F+FG L+ K
Sbjct: 240 A-HYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALS 298
Query: 983 QKLTNLFSNFIKLGDPS 999
++ ++NF + G+P+
Sbjct: 299 LQMMKYWANFARTGNPN 315
Score = 50.4 bits (115), Expect = 3e-05
Identities = 23/71 (32%), Positives = 39/71 (54%)
Query: 262 ALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWAL 321
AL+W++ NIA FGG+P + + G+ I L +S + F +AI++SG+ L +
Sbjct: 3 ALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRPFI 62
Query: 322 DRNPALTGEKL 332
NP +K+
Sbjct: 63 TSNPLKVAKKV 73
Score = 36.7 bits (81), Expect = 0.44
Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 8/137 (5%)
Query: 468 DSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDG 527
D+ F+ ++TA +AG VY YEF E + V +GA GD ++F
Sbjct: 229 DATFVYATLQTAHYHRDAGLPVYLYEF---EHHARGIIVKPRTDGADHGDEMYFLFGGPF 285
Query: 528 RILTEGTAEREVVDIMVDTWFTFIENGNP-VANETDWNRLTVTVPAQEEWMQLGPEIGLK 586
E+ + M+ W F GNP N W R E+++QL +
Sbjct: 286 ATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYN----KDEKYLQLDFTTRVG 341
Query: 587 QGLHLSRLNLWTNIYNN 603
L ++ W ++Y +
Sbjct: 342 MKLKEKKMAFWMSLYQS 358
>BC032567-1|AAH32567.1| 134|Homo sapiens NLGN4Y protein protein.
Length = 134
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 650 EVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKG-IIIVTFNYRIGVLG 697
E ++ PV+V++HGG Y G G L + G +I++T NYR+G+LG
Sbjct: 59 EQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILG 107
>D38441-1|BAA07476.1| 732|Homo sapiens acylamino acid-releasing
enzyme protein.
Length = 732
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%)
Query: 638 DENCLVINIFTPEVSNNLPVLVHVHGGDYQN---GWGFHQPPINLINKGIIIVTFNYRIG 694
D +++ +P +P++V HGG + + W P L G ++ NYR G
Sbjct: 483 DFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLF--PAMLCKMGFAVLLVNYR-G 539
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLY-GTEAGSISIQLLLQ 753
GF I + PGNVG +D + ++Q ++ D + V L G+ G IS L+ Q
Sbjct: 540 STGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQ 599
>BC001826-1|AAH01826.1| 732|Homo sapiens N-acylaminoacyl-peptide
hydrolase protein.
Length = 732
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%)
Query: 638 DENCLVINIFTPEVSNNLPVLVHVHGGDYQN---GWGFHQPPINLINKGIIIVTFNYRIG 694
D +++ +P +P++V HGG + + W P L G ++ NYR G
Sbjct: 483 DFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLF--PAMLCKMGFAVLLVNYR-G 539
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLY-GTEAGSISIQLLLQ 753
GF I + PGNVG +D + ++Q ++ D + V L G+ G IS L+ Q
Sbjct: 540 STGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQ 599
>BC001499-1|AAH01499.1| 732|Homo sapiens N-acylaminoacyl-peptide
hydrolase protein.
Length = 732
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%)
Query: 638 DENCLVINIFTPEVSNNLPVLVHVHGGDYQN---GWGFHQPPINLINKGIIIVTFNYRIG 694
D +++ +P +P++V HGG + + W P L G ++ NYR G
Sbjct: 483 DFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLF--PAMLCKMGFAVLLVNYR-G 539
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLY-GTEAGSISIQLLLQ 753
GF I + PGNVG +D + ++Q ++ D + V L G+ G IS L+ Q
Sbjct: 540 STGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQ 599
>BC000362-1|AAH00362.1| 732|Homo sapiens N-acylaminoacyl-peptide
hydrolase protein.
Length = 732
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%)
Query: 638 DENCLVINIFTPEVSNNLPVLVHVHGGDYQN---GWGFHQPPINLINKGIIIVTFNYRIG 694
D +++ +P +P++V HGG + + W P L G ++ NYR G
Sbjct: 483 DFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLF--PAMLCKMGFAVLLVNYR-G 539
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLY-GTEAGSISIQLLLQ 753
GF I + PGNVG +D + ++Q ++ D + V L G+ G IS L+ Q
Sbjct: 540 STGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQ 599
>AF141383-1|AAF37321.1| 732|Homo sapiens oxidized protein hydrolase
protein.
Length = 732
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%)
Query: 638 DENCLVINIFTPEVSNNLPVLVHVHGGDYQN---GWGFHQPPINLINKGIIIVTFNYRIG 694
D +++ +P +P++V HGG + + W P L G ++ NYR G
Sbjct: 483 DFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLF--PAMLCKMGFAVLLVNYR-G 539
Query: 695 VLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLY-GTEAGSISIQLLLQ 753
GF I + PGNVG +D + ++Q ++ D + V L G+ G IS L+ Q
Sbjct: 540 STGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQ 599
>AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein.
Length = 550
Score = 35.9 bits (79), Expect = 0.77
Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 20/203 (9%)
Query: 307 KAITESGSVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILT-----------ILR 355
KAI +SG+ +S W+++ P L +L A D + E + L +
Sbjct: 1 KAIAQSGTAISSWSVNYQP-LKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQP 59
Query: 356 AAQNIHFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLNEALD--QNEASI 412
A +I F P ++ P P ++++ E +N +IG GL D ++E +
Sbjct: 60 ARYHIAFGPVVDGDVVP---DDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGV 116
Query: 413 EQLNDDFATLLPDDLAFGSDIERQNVVRN-VRSQYFIENKPITLEDHIEGLSLCFTDSCF 471
DF D +G E ++V+R ++ Y E + L FTD +
Sbjct: 117 SASAFDFTVSNFVDNLYGYP-EGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQW 175
Query: 472 LGPAIRTARSLANAGAKVYFYEF 494
+ PA+ TA+ A+ + VYFY F
Sbjct: 176 VAPAVATAKLHADYQSPVYFYTF 198
>L32179-1|AAA35551.1| 399|Homo sapiens arylacetamide deacetylase
protein.
Length = 399
Score = 35.5 bits (78), Expect = 1.0
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 18/99 (18%)
Query: 200 LFHIHESNFVQGSADPALYGPEYLVS-----KGLILVLPNYRLGPLGFLCLRNTMAPGNA 254
LF+IH + GSA AL G + L ++V NYRL P ++
Sbjct: 107 LFYIHGGGWCVGSA--ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQ-------- 156
Query: 255 ALKDLSMALQWI--KNNIAKFGGNPDTIVVSGEGTSGAL 291
+D+ AL+W K +AK+G NP+ I +SG+ G L
Sbjct: 157 -FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNL 194
>J03068-1|AAA35769.1| 606|Homo sapiens protein ( Human DNF1552
(lung) mRNA, complete cds. ).
Length = 606
Score = 35.5 bits (78), Expect = 1.0
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 676 PINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPND 735
P L G ++ NYR G GF I + PGNVG +D + ++Q ++ D +
Sbjct: 418 PAMLCKMGFAVLLVNYR-GSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASH 476
Query: 736 VTLY-GTEAGSISIQLLLQ 753
V L G+ G IS L+ Q
Sbjct: 477 VXLMGGSHGGFISCHLIGQ 495
>BC032309-1|AAH32309.1| 399|Homo sapiens arylacetamide deacetylase
(esterase) protein.
Length = 399
Score = 35.5 bits (78), Expect = 1.0
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 18/99 (18%)
Query: 200 LFHIHESNFVQGSADPALYGPEYLVS-----KGLILVLPNYRLGPLGFLCLRNTMAPGNA 254
LF+IH + GSA AL G + L ++V NYRL P ++
Sbjct: 107 LFYIHGGGWCVGSA--ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQ-------- 156
Query: 255 ALKDLSMALQWI--KNNIAKFGGNPDTIVVSGEGTSGAL 291
+D+ AL+W K +AK+G NP+ I +SG+ G L
Sbjct: 157 -FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNL 194
>BC075022-1|AAH75022.1| 543|Homo sapiens potassium channel,
subfamily K, member 10, isoform 3 protein.
Length = 543
Score = 33.9 bits (74), Expect = 3.1
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 790 QLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNA-ESLIDKDPLQLLKDGP- 847
+LG + +S +L K SV LD + ES+NN +L K P QL K G
Sbjct: 384 RLGLDQRAHSLDMLSP-EKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQG 442
Query: 848 --IDNI-PMLVSYTRLKLRHNSEKLKTVPED 875
DNI S +RL R N + KT+PED
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPED 473
>BC075021-1|AAH75021.1| 543|Homo sapiens potassium channel,
subfamily K, member 10, isoform 3 protein.
Length = 543
Score = 33.9 bits (74), Expect = 3.1
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 790 QLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNA-ESLIDKDPLQLLKDGP- 847
+LG + +S +L K SV LD + ES+NN +L K P QL K G
Sbjct: 384 RLGLDQRAHSLDMLSP-EKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQG 442
Query: 848 --IDNI-PMLVSYTRLKLRHNSEKLKTVPED 875
DNI S +RL R N + KT+PED
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPED 473
>AF385400-1|AAL95706.1| 543|Homo sapiens potassium channel TREK2
splice variant c protein.
Length = 543
Score = 33.9 bits (74), Expect = 3.1
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 790 QLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNA-ESLIDKDPLQLLKDGP- 847
+LG + +S +L K SV LD + ES+NN +L K P QL K G
Sbjct: 384 RLGLDQRAHSLDMLSP-EKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQG 442
Query: 848 --IDNI-PMLVSYTRLKLRHNSEKLKTVPED 875
DNI S +RL R N + KT+PED
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPED 473
>AF385399-1|AAL95705.1| 543|Homo sapiens potassium channel TREK2
splice variant b protein.
Length = 543
Score = 33.9 bits (74), Expect = 3.1
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 790 QLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNA-ESLIDKDPLQLLKDGP- 847
+LG + +S +L K SV LD + ES+NN +L K P QL K G
Sbjct: 384 RLGLDQRAHSLDMLSP-EKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQG 442
Query: 848 --IDNI-PMLVSYTRLKLRHNSEKLKTVPED 875
DNI S +RL R N + KT+PED
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPED 473
>AF279890-1|AAG15191.1| 538|Homo sapiens 2P domain potassium
channel TREK2 protein.
Length = 538
Score = 33.9 bits (74), Expect = 3.1
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 790 QLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNA-ESLIDKDPLQLLKDGP- 847
+LG + +S +L K SV LD + ES+NN +L K P QL K G
Sbjct: 379 RLGLDQRAHSLDMLSP-EKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQG 437
Query: 848 --IDNI-PMLVSYTRLKLRHNSEKLKTVPED 875
DNI S +RL R N + KT+PED
Sbjct: 438 ASEDNIINKFGSTSRLTKRKNKDLKKTLPED 468
>AK074522-1|BAC11039.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ90041 fis, clone HEMBA1002167, highly similar to
Rattus norvegicus neuroligin I mRNA. ).
Length = 509
Score = 33.1 bits (72), Expect = 5.4
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 8/143 (5%)
Query: 356 AAQNIHFRPCIEKGNNPFMTQTPWGMIREQE-VNITFMIGSANYAGLN--EALDQNEASI 412
A +I F P I+ P P ++ + E +N M+G GL E + ++ I
Sbjct: 36 ARYHIAFGPVIDGDVIP---DDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGI 92
Query: 413 EQLNDDFATLLPDDLAFGSDIERQNVVRN-VRSQYFIENKPITLEDHIEGLSLCFTDSCF 471
+ DFA D +G E ++V+R ++ Y E + L FTD +
Sbjct: 93 SASDFDFAVSNFVDNLYGYP-EGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQW 151
Query: 472 LGPAIRTARSLANAGAKVYFYEF 494
+ PA+ TA +N G+ YFY F
Sbjct: 152 VAPAVATADLHSNFGSPTYFYAF 174
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 157,211,705
Number of Sequences: 224733
Number of extensions: 6899277
Number of successful extensions: 14776
Number of sequences better than 10.0: 105
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 14169
Number of HSP's gapped (non-prelim): 310
length of query: 1064
length of database: 73,234,838
effective HSP length: 98
effective length of query: 966
effective length of database: 51,211,004
effective search space: 49469829864
effective search space used: 49469829864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 70 (32.3 bits)
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