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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000774-TA|BGIBMGA000774-PA|IPR002018|Carboxylesterase,
type B
         (566 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.        170   1e-41
BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.        170   1e-41
AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5 prot...   170   1e-41
AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens ...   165   4e-40
BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked ...   162   3e-39
BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked ...   162   3e-39
AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.        162   3e-39
M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase pro...   160   1e-38
M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.                  160   1e-38
M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.                  160   1e-38
BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase p...   160   1e-38
BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked ...   160   1e-38
AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.        160   1e-38
AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.    160   1e-38
Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.      158   6e-38
U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.      158   6e-38
D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precurso...   158   6e-38
BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2 (int...   158   6e-38
AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2 (int...   158   6e-38
AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isof...   158   6e-38
BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.       154   9e-37
M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase prot...   153   2e-36
BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase, i...   153   2e-36
BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Y...   153   2e-36
BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.        153   2e-36
AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (Y...   153   2e-36
AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.             153   2e-36
AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.             153   2e-36
AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.        152   3e-36
AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.               151   5e-36
BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.        151   6e-36
AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase is...   150   1e-35
BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.        149   3e-35
AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.    149   3e-35
BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1 (mon...   149   3e-35
L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.      147   1e-34
X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for ...   146   1e-34
M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase pro...   146   1e-34
M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase prot...   146   1e-34
M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipas...   146   1e-34
AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase (...   146   1e-34
AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lip...   146   1e-34
AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase p...   146   1e-34
S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholester...   146   2e-34
M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.      146   2e-34
D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.      146   2e-34
BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1 (mon...   146   2e-34
BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7 prot...   146   2e-34
BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.         146   2e-34
AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens ...   146   2e-34
AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.              146   2e-34
AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b p...   146   2e-34
AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a p...   146   2e-34
AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b p...   146   2e-34
AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a p...   146   2e-34
AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform pr...   145   4e-34
BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.        144   6e-34
S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipas...   144   7e-34
L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.      144   7e-34
BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.        143   2e-33
BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.        143   2e-33
AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo pr...   143   2e-33
AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester hydro...   142   2e-33
BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.        142   3e-33
AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HN...   142   3e-33
AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.    142   3e-33
BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.    141   5e-33
AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase ...   140   9e-33
BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein pr...   137   8e-32
X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage serin...   136   1e-31
AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related acety...   136   2e-31
AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform pr...   135   3e-31
AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HN...   135   3e-31
AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.    135   3e-31
AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo pr...   135   5e-31
AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase ...   134   6e-31
M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.      134   1e-30
M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.      132   4e-30
AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase ...   131   7e-30
BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.    130   1e-29
AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-relate...   122   4e-27
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.         117   1e-25
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.       117   1e-25
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor...   117   1e-25
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.         115   5e-25
BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for IM...   113   1e-24
BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.         97   2e-19
AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens ...    97   2e-19
AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens ...    93   2e-18
BC032567-1|AAH32567.1|  134|Homo sapiens NLGN4Y protein protein.       49   5e-05
BC009706-1|AAH09706.1|  150|Homo sapiens CES1 protein protein.         39   0.054
L32179-1|AAA35551.1|  399|Homo sapiens arylacetamide deacetylase...    36   0.38 
BC032309-1|AAH32309.1|  399|Homo sapiens arylacetamide deacetyla...    36   0.38 
AL513016-5|CAH74176.2|  350|Homo sapiens arylacetamide deacetyla...    35   0.67 
BC069238-1|AAH69238.1|  403|Homo sapiens zinc finger, CCHC domai...    34   1.5  
AL034548-4|CAB81631.1|  404|Homo sapiens zinc finger, CCHC domai...    34   1.5  
BC065724-1|AAH65724.1|  379|Homo sapiens arylacetamide deacetyla...    33   3.6  
AL513016-2|CAH74173.1|  407|Homo sapiens arylacetamide deacetyla...    32   4.7  
AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.     32   4.7  
AL513016-4|CAH74175.1|  280|Homo sapiens arylacetamide deacetyla...    31   8.2  

>BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  170 bits (414), Expect = 1e-41
 Identities = 144/499 (28%), Positives = 223/499 (44%), Gaps = 46/499 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR------DITYGSITVKRKG 102
           F G+P+A PP+G+ RF              A      C         D     +   + G
Sbjct: 57  FLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFG 116

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +DV
Sbjct: 117 VSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYEDV 168

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESAG
Sbjct: 169 LVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
           A SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S+
Sbjct: 229 AISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--SE 286

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKD 342
            + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K 
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFKA 334

Query: 343 IPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRY 402
           IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   Y
Sbjct: 335 IPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANEY 389

Query: 403 FDGEPTV----DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD-FSITKRA 457
           F  + ++    D  +  + D++F  P +  A++      AP YFYEF +    F  TK A
Sbjct: 390 FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-RDAGAPVYFYEFRHRPQCFEDTKPA 448

Query: 458 NWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTLFSNYVRCNNPTCN 516
               +    H +++ +VF      G  V     T ++++    M   ++ + R  NP  N
Sbjct: 449 ----FVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNP--N 502

Query: 517 KRDDPRWPPINEEELMFQV 535
             D   WP  N  E   Q+
Sbjct: 503 GNDLSLWPAYNLTEQYLQL 521


>BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  170 bits (414), Expect = 1e-41
 Identities = 144/499 (28%), Positives = 223/499 (44%), Gaps = 46/499 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR------DITYGSITVKRKG 102
           F G+P+A PP+G+ RF              A      C         D     +   + G
Sbjct: 57  FLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFG 116

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +DV
Sbjct: 117 VSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYEDV 168

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESAG
Sbjct: 169 LVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
           A SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S+
Sbjct: 229 AISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--SE 286

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKD 342
            + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K 
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFKA 334

Query: 343 IPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRY 402
           IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   Y
Sbjct: 335 IPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANEY 389

Query: 403 FDGEPTV----DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD-FSITKRA 457
           F  + ++    D  +  + D++F  P +  A++      AP YFYEF +    F  TK A
Sbjct: 390 FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-RDAGAPVYFYEFRHRPQCFEDTKPA 448

Query: 458 NWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTLFSNYVRCNNPTCN 516
               +    H +++ +VF      G  V     T ++++    M   ++ + R  NP  N
Sbjct: 449 ----FVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNP--N 502

Query: 517 KRDDPRWPPINEEELMFQV 535
             D   WP  N  E   Q+
Sbjct: 503 GNDLSLWPAYNLTEQYLQL 521


>AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5
           protein.
          Length = 575

 Score =  170 bits (414), Expect = 1e-41
 Identities = 144/499 (28%), Positives = 223/499 (44%), Gaps = 46/499 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR------DITYGSITVKRKG 102
           F G+P+A PP+G+ RF              A      C         D     +   + G
Sbjct: 57  FLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFG 116

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +DV
Sbjct: 117 VSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYEDV 168

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESAG
Sbjct: 169 LVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
           A SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S+
Sbjct: 229 AISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--SE 286

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKD 342
            + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K 
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFKA 334

Query: 343 IPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRY 402
           IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   Y
Sbjct: 335 IPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANEY 389

Query: 403 FDGEPTV----DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD-FSITKRA 457
           F  + ++    D  +  + D++F  P +  A++      AP YFYEF +    F  TK A
Sbjct: 390 FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-RDAGAPVYFYEFRHRPQCFEDTKPA 448

Query: 458 NWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTLFSNYVRCNNPTCN 516
               +    H +++ +VF      G  V     T ++++    M   ++ + R  NP  N
Sbjct: 449 ----FVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNP--N 502

Query: 517 KRDDPRWPPINEEELMFQV 535
             D   WP  N  E   Q+
Sbjct: 503 GNDLSLWPAYNLTEQYLQL 521


>AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 469

 Score =  165 bits (401), Expect = 4e-40
 Identities = 132/440 (30%), Positives = 205/440 (46%), Gaps = 40/440 (9%)

Query: 102 GMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKD 161
           G+SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +D
Sbjct: 10  GVSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYED 61

Query: 162 VIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESA 221
           V+VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESA
Sbjct: 62  VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 121

Query: 222 GAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTS 281
           GA SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S
Sbjct: 122 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--S 179

Query: 282 DEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGK 341
           + + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K
Sbjct: 180 EALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFK 227

Query: 342 DIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKR 401
            IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   
Sbjct: 228 AIPSIIGVNSHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANE 282

Query: 402 YFDGEPTV----DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD-FSITKR 456
           YF  + ++    D  +  + D++F  P +  A++      AP YFYEF +    F  TK 
Sbjct: 283 YFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-RDAGAPVYFYEFRHRPQCFEDTKP 341

Query: 457 ANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTLFSNYVRCNNPTC 515
           A    +    H +++ +VF      G  V     T ++++    M   ++ + R  NP  
Sbjct: 342 A----FVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNP-- 395

Query: 516 NKRDDPRWPPINEEELMFQV 535
           N  D   WP  N  E   Q+
Sbjct: 396 NGNDLSLWPAYNLTEQYLQL 415


>BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  162 bits (394), Expect = 3e-39
 Identities = 141/490 (28%), Positives = 226/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR---------------DITY 93
           + G+PYA PP G RRF              A +    CP                   + 
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 94  GSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
            ++    +  +E+C+Y N++VP       D++ E NS  P++V IHGG +  G+GN  + 
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME-----DDIHEQNSKKPVMVYIHGGSYMEGTGNM-ID 186

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 304

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 305 GCNMLD-TTDMVECLKNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 354

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 355 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 412

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 413 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 471

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 472 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 526

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 527 WTNFAKTGDP 536


>BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  162 bits (394), Expect = 3e-39
 Identities = 141/490 (28%), Positives = 226/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR---------------DITY 93
           + G+PYA PP G RRF              A +    CP                   + 
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 94  GSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
            ++    +  +E+C+Y N++VP       D++ E NS  P++V IHGG +  G+GN  + 
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME-----DDIHEQNSKKPVMVYIHGGSYMEGTGNM-ID 186

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 304

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 305 GCNMLD-TTDMVECLKNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 354

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 355 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 412

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 413 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 471

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 472 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 526

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 527 WTNFAKTGDP 536


>AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.
          Length = 816

 Score =  162 bits (394), Expect = 3e-39
 Identities = 141/490 (28%), Positives = 226/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR---------------DITY 93
           + G+PYA PP G RRF              A +    CP                   + 
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 94  GSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
            ++    +  +E+C+Y N++VP       D++ E NS  P++V IHGG +  G+GN  + 
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME-----DDIHEQNSKKPVMVYIHGGSYMEGTGNM-ID 186

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 304

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 305 GCNMLD-TTDMVECLKNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 354

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 355 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 412

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 413 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 471

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 472 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 526

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 527 WTNFAKTGDP 536


>M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  160 bits (389), Expect = 1e-38
 Identities = 156/571 (27%), Positives = 259/571 (45%), Gaps = 63/571 (11%)

Query: 2   FVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVGA 61
           F+LL +++G     +S T+  D+++   +G V G   +    T   +F GIPYA+PP+G 
Sbjct: 16  FLLLCMLIG-----KSHTED-DIIIATKNGKVRGMNLTVFGGT-VTAFLGIPYAQPPLGR 68

Query: 62  RRFXXXXXXXXXXXXFYAYE-EGPACPSRDITY----GS-ITVKRKGMSENCIYANVFVP 115
            RF            + A +     C + D ++    GS +      +SE+C+Y NV++P
Sbjct: 69  LRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP 128

Query: 116 ASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAIF 174
           A    N+          +L+ I+GGGFQTG+ +  ++ G  L  ++ VIVV+ NYR+   
Sbjct: 129 APKPKNAT---------VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179

Query: 175 GYLSLASH-KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSR 233
           G+L+L  + + PGN GL D    L+WVQ+N   FGG+PK VT+ GESAGAASV L +LS 
Sbjct: 180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSP 239

Query: 234 ASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPL 293
            S  LF +AI+ SG+    +  +S +Y      + L +L   S E  ++ I     + P 
Sbjct: 240 GSHSLFTRAILQSGSFNAPWAVTS-LYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQ 298

Query: 294 DDIMRANDVVQYRAGLT-SFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKD 352
           + ++    VV Y   L+ +F P V+ +       + D P  L+  G  K   +L+G NKD
Sbjct: 299 EILLNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQFKKTQILVGVNKD 352

Query: 353 EGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELP-----PQEASAKGIFVGKRYFDGEP 407
           EG  F     +Y      K N ++I        L        E   + I      +  + 
Sbjct: 353 EGTAF----LVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQ 408

Query: 408 TVDGFVKSVTDIYFQYPMI--------KLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
             + + +++ D+   Y  I        K ++W    N+A  +FY F + S      +  W
Sbjct: 409 RPENYREALGDVVGDYNFICPALEFTKKFSEWG---NNA--FFYYFEHRS-----SKLPW 458

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRD 519
             + G  H  ++ +VF          +   K  +   R  +   ++N+ +  NP   + +
Sbjct: 459 PEWMGVMHGYEIEFVFGLPLERRDNYT---KAEEILSRSIVKR-WANFAKYGNPNETQNN 514

Query: 520 DPRWPPINEEELMFQVIKEPNVYKMSSLPKQ 550
              WP     E  +  +   +   M+ L  Q
Sbjct: 515 STSWPVFKSTEQKYLTLNTESTRIMTKLRAQ 545


>M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  160 bits (389), Expect = 1e-38
 Identities = 156/571 (27%), Positives = 259/571 (45%), Gaps = 63/571 (11%)

Query: 2   FVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVGA 61
           F+LL +++G     +S T+  D+++   +G V G   +    T   +F GIPYA+PP+G 
Sbjct: 16  FLLLCMLIG-----KSHTED-DIIIATKNGKVRGMNLTVFGGT-VTAFLGIPYAQPPLGR 68

Query: 62  RRFXXXXXXXXXXXXFYAYE-EGPACPSRDITY----GS-ITVKRKGMSENCIYANVFVP 115
            RF            + A +     C + D ++    GS +      +SE+C+Y NV++P
Sbjct: 69  LRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP 128

Query: 116 ASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAIF 174
           A    N+          +L+ I+GGGFQTG+ +  ++ G  L  ++ VIVV+ NYR+   
Sbjct: 129 APKPKNAT---------VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179

Query: 175 GYLSLASH-KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSR 233
           G+L+L  + + PGN GL D    L+WVQ+N   FGG+PK VT+ GESAGAASV L +LS 
Sbjct: 180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSP 239

Query: 234 ASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPL 293
            S  LF +AI+ SG+    +  +S +Y      + L +L   S E  ++ I     + P 
Sbjct: 240 GSHSLFTRAILQSGSFNAPWAVTS-LYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQ 298

Query: 294 DDIMRANDVVQYRAGLT-SFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKD 352
           + ++    VV Y   L+ +F P V+ +       + D P  L+  G  K   +L+G NKD
Sbjct: 299 EILLNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQFKKTQILVGVNKD 352

Query: 353 EGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELP-----PQEASAKGIFVGKRYFDGEP 407
           EG  F     +Y      K N ++I        L        E   + I      +  + 
Sbjct: 353 EGTAF----LVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQ 408

Query: 408 TVDGFVKSVTDIYFQYPMI--------KLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
             + + +++ D+   Y  I        K ++W    N+A  +FY F + S      +  W
Sbjct: 409 RPENYREALGDVVGDYNFICPALEFTKKFSEWG---NNA--FFYYFEHRS-----SKLPW 458

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRD 519
             + G  H  ++ +VF          +   K  +   R  +   ++N+ +  NP   + +
Sbjct: 459 PEWMGVMHGYEIEFVFGLPLERRDNYT---KAEEILSRSIVKR-WANFAKYGNPNETQNN 514

Query: 520 DPRWPPINEEELMFQVIKEPNVYKMSSLPKQ 550
              WP     E  +  +   +   M+ L  Q
Sbjct: 515 STSWPVFKSTEQKYLTLNTESTRIMTKLRAQ 545


>M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  160 bits (389), Expect = 1e-38
 Identities = 156/571 (27%), Positives = 259/571 (45%), Gaps = 63/571 (11%)

Query: 2   FVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVGA 61
           F+LL +++G     +S T+  D+++   +G V G   +    T   +F GIPYA+PP+G 
Sbjct: 16  FLLLCMLIG-----KSHTED-DIIIATKNGKVRGMNLTVFGGT-VTAFLGIPYAQPPLGR 68

Query: 62  RRFXXXXXXXXXXXXFYAYE-EGPACPSRDITY----GS-ITVKRKGMSENCIYANVFVP 115
            RF            + A +     C + D ++    GS +      +SE+C+Y NV++P
Sbjct: 69  LRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP 128

Query: 116 ASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAIF 174
           A    N+          +L+ I+GGGFQTG+ +  ++ G  L  ++ VIVV+ NYR+   
Sbjct: 129 APKPKNAT---------VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179

Query: 175 GYLSLASH-KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSR 233
           G+L+L  + + PGN GL D    L+WVQ+N   FGG+PK VT+ GESAGAASV L +LS 
Sbjct: 180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSP 239

Query: 234 ASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPL 293
            S  LF +AI+ SG+    +  +S +Y      + L +L   S E  ++ I     + P 
Sbjct: 240 GSHSLFTRAILQSGSFNAPWAVTS-LYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQ 298

Query: 294 DDIMRANDVVQYRAGLT-SFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKD 352
           + ++    VV Y   L+ +F P V+ +       + D P  L+  G  K   +L+G NKD
Sbjct: 299 EILLNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQFKKTQILVGVNKD 352

Query: 353 EGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELP-----PQEASAKGIFVGKRYFDGEP 407
           EG  F     +Y      K N ++I        L        E   + I      +  + 
Sbjct: 353 EGTAF----LVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQ 408

Query: 408 TVDGFVKSVTDIYFQYPMI--------KLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
             + + +++ D+   Y  I        K ++W    N+A  +FY F + S      +  W
Sbjct: 409 RPENYREALGDVVGDYNFICPALEFTKKFSEWG---NNA--FFYYFEHRS-----SKLPW 458

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRD 519
             + G  H  ++ +VF          +   K  +   R  +   ++N+ +  NP   + +
Sbjct: 459 PEWMGVMHGYEIEFVFGLPLERRDNYT---KAEEILSRSIVKR-WANFAKYGNPNETQNN 514

Query: 520 DPRWPPINEEELMFQVIKEPNVYKMSSLPKQ 550
              WP     E  +  +   +   M+ L  Q
Sbjct: 515 STSWPVFKSTEQKYLTLNTESTRIMTKLRAQ 545


>BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  160 bits (389), Expect = 1e-38
 Identities = 156/571 (27%), Positives = 259/571 (45%), Gaps = 63/571 (11%)

Query: 2   FVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVGA 61
           F+LL +++G     +S T+  D+++   +G V G   +    T   +F GIPYA+PP+G 
Sbjct: 16  FLLLCMLIG-----KSHTED-DIIIATKNGKVRGMNLTVFGGT-VTAFLGIPYAQPPLGR 68

Query: 62  RRFXXXXXXXXXXXXFYAYE-EGPACPSRDITY----GS-ITVKRKGMSENCIYANVFVP 115
            RF            + A +     C + D ++    GS +      +SE+C+Y NV++P
Sbjct: 69  LRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP 128

Query: 116 ASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAIF 174
           A    N+          +L+ I+GGGFQTG+ +  ++ G  L  ++ VIVV+ NYR+   
Sbjct: 129 APKPKNAT---------VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179

Query: 175 GYLSLASH-KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSR 233
           G+L+L  + + PGN GL D    L+WVQ+N   FGG+PK VT+ GESAGAASV L +LS 
Sbjct: 180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSP 239

Query: 234 ASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPL 293
            S  LF +AI+ SG+    +  +S +Y      + L +L   S E  ++ I     + P 
Sbjct: 240 GSHSLFTRAILQSGSFNAPWAVTS-LYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQ 298

Query: 294 DDIMRANDVVQYRAGLT-SFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKD 352
           + ++    VV Y   L+ +F P V+ +       + D P  L+  G  K   +L+G NKD
Sbjct: 299 EILLNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQFKKTQILVGVNKD 352

Query: 353 EGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELP-----PQEASAKGIFVGKRYFDGEP 407
           EG  F     +Y      K N ++I        L        E   + I      +  + 
Sbjct: 353 EGTAF----LVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQ 408

Query: 408 TVDGFVKSVTDIYFQYPMI--------KLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
             + + +++ D+   Y  I        K ++W    N+A  +FY F + S      +  W
Sbjct: 409 RPENYREALGDVVGDYNFICPALEFTKKFSEWG---NNA--FFYYFEHRS-----SKLPW 458

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRD 519
             + G  H  ++ +VF          +   K  +   R  +   ++N+ +  NP   + +
Sbjct: 459 PEWMGVMHGYEIEFVFGLPLERRDNYT---KAEEILSRSIVKR-WANFAKYGNPNETQNN 514

Query: 520 DPRWPPINEEELMFQVIKEPNVYKMSSLPKQ 550
              WP     E  +  +   +   M+ L  Q
Sbjct: 515 STSWPVFKSTEQKYLTLNTESTRIMTKLRAQ 545


>BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked
           protein.
          Length = 816

 Score =  160 bits (388), Expect = 1e-38
 Identities = 140/490 (28%), Positives = 227/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPS----RDITYGSITV------ 98
           + G+PYA PP G RRF                +    CP     R + +  + +      
Sbjct: 73  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 132

Query: 99  -----KRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
                  +  +E+C+Y N++VP       D++ + NS  P++V IHGG +  G+GN  + 
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPTE-----DDIHDQNSKKPVMVYIHGGSYMEGTGNM-ID 186

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 304

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 305 GCNMLD-TTDMVECLRNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 354

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 355 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 412

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 413 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 471

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 472 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 526

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 527 WTNFAKTGDP 536


>AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.
          Length = 816

 Score =  160 bits (388), Expect = 1e-38
 Identities = 140/490 (28%), Positives = 227/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPS----RDITYGSITV------ 98
           + G+PYA PP G RRF                +    CP     R + +  + +      
Sbjct: 73  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 132

Query: 99  -----KRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
                  +  +E+C+Y N++VP       D++ + NS  P++V IHGG +  G+GN  + 
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPTE-----DDIHDQNSKKPVMVYIHGGSYMEGTGNM-ID 186

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 304

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 305 GCNMLD-TTDMVECLRNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 354

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 355 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 412

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 413 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 471

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 472 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 526

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 527 WTNFAKTGDP 536


>AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.
          Length = 817

 Score =  160 bits (388), Expect = 1e-38
 Identities = 140/490 (28%), Positives = 227/490 (46%), Gaps = 51/490 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPS----RDITYGSITV------ 98
           + G+PYA PP G RRF                +    CP     R + +  + +      
Sbjct: 74  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 133

Query: 99  -----KRKGMSENCIYANVFVPASATLNSDELCEDNSL-PILVNIHGGGFQTGSGNRDLH 152
                  +  +E+C+Y N++VP       D++ + NS  P++V IHGG +  G+GN  + 
Sbjct: 134 DTLMTYVQDQNEDCLYLNIYVPTE-----DDIHDQNSKKPVMVYIHGGSYMEGTGNM-ID 187

Query: 153 GPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPK 212
           G  L    +VIV+  NYRL I G+LS       GN GL D +  L+W++ N   FGGDPK
Sbjct: 188 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 247

Query: 213 RVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGEL 272
           RVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +   AKY + +   ++
Sbjct: 248 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVNYQPAKY-TRILADKV 305

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
           G N  + T+D +     +   + I +      Y     +F PV++ +      +I DDP 
Sbjct: 306 GCNMLD-TTDMVECLRNKNYKELIQQTITPATYH---IAFGPVIDGD------VIPDDPQ 355

Query: 333 TLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNP---AVILSPRLAYELPPQ 389
            L+ QG   +  +++G N+ EG   K++  I +  D    N    +V       Y  P  
Sbjct: 356 ILMEQGEFLNYDIMLGVNQGEG--LKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEG 413

Query: 390 EASAKGI--FVGKRYFDGE-PTV--DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + + +    F+   + D E P       V   TD  +  P +  A       S PTYFY 
Sbjct: 414 KDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS-PTYFYA 472

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRD-WMSTL 503
           F +     +  + +W     +AH +++ YVF       +++     +++D M    + T 
Sbjct: 473 FYHHCQSEM--KPSWAD---SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTY 527

Query: 504 FSNYVRCNNP 513
           ++N+ +  +P
Sbjct: 528 WTNFAKTGDP 537


>Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.
          Length = 559

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 57  TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 116

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 117 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 168

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 169 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 228

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 229 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 283

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 284 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 331

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 332 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 388

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 389 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 443

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 444 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 497

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 498 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 526


>U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.
          Length = 550

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 48  TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 107

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 108 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 159

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 160 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 219

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 220 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 274

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 275 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 322

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 323 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 379

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 380 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 434

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 435 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 488

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 489 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 517


>D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precursor
           protein.
          Length = 559

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 57  TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 116

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 117 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 168

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 169 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 228

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 229 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 283

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 284 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 331

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 332 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 388

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 389 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 443

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 444 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 497

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 498 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 526


>BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 181 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 232

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 233 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 292

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 293 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 347

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 348 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 395

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 396 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 452

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 453 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 507

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 508 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 561

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 562 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 590


>AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 181 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 232

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 233 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 292

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 293 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 347

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 348 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 395

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 396 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 452

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 453 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 507

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 508 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 561

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 562 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 590


>AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isoform
           1 variant protein.
          Length = 582

 Score =  158 bits (383), Expect = 6e-38
 Identities = 144/511 (28%), Positives = 235/511 (45%), Gaps = 58/511 (11%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 80  TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 139

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 140 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 191

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 192 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 251

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 252 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 306

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 307 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPKELLASAD 354

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 355 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 411

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 412 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQPS 466

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           +    R     +    H ++L +VF   +F G    +     ++Q+   M   ++N+ R 
Sbjct: 467 WLKNIRP---PHMKADHGDELPFVFR--SFFGGNY-IKFTEEEEQLSRKMMKYWANFARN 520

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 521 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 549


>BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.
          Length = 518

 Score =  154 bits (373), Expect = 9e-37
 Identities = 129/449 (28%), Positives = 208/449 (46%), Gaps = 48/449 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDIT--------------YG 94
           + G+PYA PP+G +RF              A    P CP    T                
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 95  SITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGP 154
            +    +  +E+C+Y NV+VP       D++ +  + P++V IHGG +  G+GN  + G 
Sbjct: 129 IVATYIQEPNEDCLYLNVYVPTE-----DDIRDSGAKPVMVYIHGGSYMEGTGNM-IDGS 182

Query: 155 ELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRV 214
            L    +VIV+  NYR+ + G+LS       GN GL D +  L+WV  N   FGGDP+R+
Sbjct: 183 ILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRI 242

Query: 215 TILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNF-YSSSPI-YAKYISDMFLGEL 272
           T+ G   GA+ V LL LS  S+GLF +AII SG+A+ ++  +  P+ Y   ++D  +G  
Sbjct: 243 TVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADK-VGCN 301

Query: 273 GLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPI 332
            L++ ++      ++  EL   DI  A    +Y     +F PV++ +      +I DDP 
Sbjct: 302 VLDTVDMVDCLRQKSAKELVEQDIQPA----RYH---VAFGPVIDGD------VIPDDPE 348

Query: 333 TLINQGVGKDIPLLMGFNKDEG-EYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEA 391
            L+ QG   +  +++G N+ EG ++ + ++   + V     + +V       Y  P  + 
Sbjct: 349 ILMEQGEFLNYDVMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKD 408

Query: 392 SAKGI--FVGKRYFD---GEPTVDGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFS 446
           + +    F+   + D    E      V   TD  +  P +  A       S PTYFY F 
Sbjct: 409 TLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGS-PTYFYAF- 466

Query: 447 YESDFSITKRANWLSYKGTAHVEDLTYVF 475
           Y    S+ K A    +   AH +++ YVF
Sbjct: 467 YHHCQSLMKPA----WSDAAHGDEVPYVF 491


>M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase
           protein.
          Length = 614

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase,
           isoform E4-E5 precursor protein.
          Length = 617

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Yt
           blood group) protein.
          Length = 617

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.
          Length = 546

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (YT
           blood group) protein.
          Length = 617

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.
          Length = 617

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.
          Length = 614

 Score =  153 bits (371), Expect = 2e-36
 Identities = 153/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.
          Length = 835

 Score =  152 bits (369), Expect = 3e-36
 Identities = 113/336 (33%), Positives = 166/336 (49%), Gaps = 41/336 (12%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR---------------DITY 93
           F G+PYA PP+GARRF              A    PACP                 D   
Sbjct: 69  FLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLE 128

Query: 94  GSITVKRKGMSENCIYANVFVPAS----------ATLN--SDELCEDNSLPILVNIHGGG 141
            + T  +   SE+C+Y N++VP            ATLN    ++ +    P+++ +HGG 
Sbjct: 129 AAATYVQN-QSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGS 187

Query: 142 FQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQ 201
           +  G+GN    G  L    +VIV   NYRL + G+LS       GN GL D +  L+W+ 
Sbjct: 188 YMEGTGNM-FDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLS 246

Query: 202 RNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYA 261
            N   FGGDP+R+TI G  AGA+ V+LL+LS  S+GLF KAI  SGTAI + +S +    
Sbjct: 247 ENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISS-WSVNYQPL 305

Query: 262 KYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGH 321
           KY + +   ++G +  +  S E  + L   P  +++   DV   R  + +F PVV+ +  
Sbjct: 306 KY-TRLLAAKVGCDRED--SAEAVECLRRKPSRELV-DQDVQPARYHI-AFGPVVDGD-- 358

Query: 322 DYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYF 357
               ++ DDP  L+ QG   +  +L+G N+ EG  F
Sbjct: 359 ----VVPDDPEILMQQGEFLNYDMLIGVNQGEGLKF 390


>AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.
          Length = 816

 Score =  151 bits (367), Expect = 5e-36
 Identities = 109/340 (32%), Positives = 167/340 (49%), Gaps = 44/340 (12%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPS----RDITYGSITV------ 98
           + G+PYA PP G RRF                +    CP     R + +  + +      
Sbjct: 54  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 113

Query: 99  -----KRKGMSENCIYANVFVP----ASATLNSDELC-----EDNSL-------PILVNI 137
                  +  +E+C+Y N++VP    A+   N+D++      ED  +       P++V I
Sbjct: 114 DTLMTYVQDQNEDCLYLNIYVPTEDGANTKKNADDITSNDRGEDEDIHDQNSKKPVMVYI 173

Query: 138 HGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLL 197
           HGG +  G+GN  + G  L    +VIV+  NYRL I G+LS       GN GL D +  L
Sbjct: 174 HGGSYMEGTGNM-IDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQAL 232

Query: 198 KWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSS 257
           +W++ N   FGGDPKRVTI G  AGA+ V LL LS  S+GLF KAII SGTA+ + ++ +
Sbjct: 233 RWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS-WAVN 291

Query: 258 PIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVE 317
              AKY + +   ++G N  + T+D +     +   + I +      Y     +F PV++
Sbjct: 292 YQPAKY-TRILADKVGCNMLD-TTDMVECLRNKNYKELIQQTITPATYH---IAFGPVID 346

Query: 318 KEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYF 357
            +      +I DDP  L+ QG   +  +++G N+ EG  F
Sbjct: 347 GD------VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF 380


>BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.
          Length = 640

 Score =  151 bits (366), Expect = 6e-36
 Identities = 151/549 (27%), Positives = 241/549 (43%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LL+ +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLVWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P++V I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVIVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYFDG 405
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y D 
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDW 416

Query: 406 EPTVD--GFVKSVTDIYFQY----PMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     ++++D+   +    P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase
           isoform E4-E6 precursor variant protein.
          Length = 614

 Score =  150 bits (364), Expect = 1e-35
 Identities = 153/549 (27%), Positives = 236/549 (42%), Gaps = 56/549 (10%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGL--NSTELTSDEIHQTLTE 290
             S+GLF++A++ SG     + +     A+  +      +G     T     E+   L  
Sbjct: 247 PPSRGLFHRAVLQSGAPNGPWATVGMGEARRRTTQLAHLVGCPPGGTGGNDTELVACLRT 306

Query: 291 LPLDDIMRA--NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMG 348
            P   ++    + + Q      SFVPVV+ +       + D P  LIN G    + +L+G
Sbjct: 307 RPAQVLVNHEWHVLPQESVFRFSFVPVVDGD------FLSDTPEALINAGDFHGLQVLVG 360

Query: 349 FNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYEL---PPQEASAKGIFVGKRYF-- 403
             KDEG YF     +Y      K N ++I        +    PQ +      V   Y   
Sbjct: 361 VVKDEGSYF----LVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTGW 416

Query: 404 ----DGEPTVDGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANW 459
               D     +     V D     P+ +LA  R+    A  Y Y F + +        +W
Sbjct: 417 LHPEDPARLREALSDVVGDHNVVCPVAQLA-GRLAAQGARVYAYVFEHRA-----STLSW 470

Query: 460 LSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQ-MRDWMSTLFSNYVRCNNPTCNKR 518
             + G  H  ++ ++F          +   K    + MR W     +N+ R  +P    R
Sbjct: 471 PLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYW-----ANFARTGDPN-EPR 524

Query: 519 DD--PRWPP 525
           D   P+WPP
Sbjct: 525 DPKAPQWPP 533


>BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.
          Length = 823

 Score =  149 bits (361), Expect = 3e-35
 Identities = 115/373 (30%), Positives = 175/373 (46%), Gaps = 50/373 (13%)

Query: 23  DVLVKLDSGPVCGREESANKNT--KYFSFQGIPYAKPPVGARRFXXXXXXXXXXXXFYAY 80
           D LV  + G + G ++  N         F G+PYA PP G RRF              A 
Sbjct: 52  DPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNAT 111

Query: 81  EEGPACPSRDI---------------TYGSITVKRKGMSENCIYANVFVPASATLNSDEL 125
           +  P CP   I                   ++   +  SE+C+Y N++VP    +     
Sbjct: 112 QFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDS-- 169

Query: 126 CEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIP 185
                 P++V IHGG +  G+GN    G  L    +VIV+  NYRL + G+LS       
Sbjct: 170 --GGPKPVMVYIHGGSYMEGTGNL-YDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAK 226

Query: 186 GNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLML---------SRASK 236
           GN GL D++  L+W   N   FGGDP R+T+ G  AG + V+LL L         S ++K
Sbjct: 227 GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTK 286

Query: 237 GLFNKAIIMSGTAIPNF-YSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDD 295
           GLF +AI  SGTA+ ++  S  P  AKY + M   ++G N ++    E+ + L + P  +
Sbjct: 287 GLFQRAIAQSGTALSSWAVSFQP--AKY-ARMLATKVGCNVSDTV--ELVECLQKKPYKE 341

Query: 296 IMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGE 355
           ++   D+   R  + +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG 
Sbjct: 342 LV-DQDIQPARYHI-AFGPVIDGD------VIPDDPQILMEQGEFLNYDIMLGVNQGEGL 393

Query: 356 YFKWIITIYNIVD 368
            F     + NIVD
Sbjct: 394 KF-----VENIVD 401


>AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.
          Length = 826

 Score =  149 bits (361), Expect = 3e-35
 Identities = 115/373 (30%), Positives = 175/373 (46%), Gaps = 50/373 (13%)

Query: 23  DVLVKLDSGPVCGREESANKNT--KYFSFQGIPYAKPPVGARRFXXXXXXXXXXXXFYAY 80
           D LV  + G + G ++  N         F G+PYA PP G RRF              A 
Sbjct: 55  DPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNAT 114

Query: 81  EEGPACPSRDI---------------TYGSITVKRKGMSENCIYANVFVPASATLNSDEL 125
           +  P CP   I                   ++   +  SE+C+Y N++VP    +     
Sbjct: 115 QFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDS-- 172

Query: 126 CEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIP 185
                 P++V IHGG +  G+GN    G  L    +VIV+  NYRL + G+LS       
Sbjct: 173 --GGPKPVMVYIHGGSYMEGTGNL-YDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAK 229

Query: 186 GNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLML---------SRASK 236
           GN GL D++  L+W   N   FGGDP R+T+ G  AG + V+LL L         S ++K
Sbjct: 230 GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTK 289

Query: 237 GLFNKAIIMSGTAIPNF-YSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDD 295
           GLF +AI  SGTA+ ++  S  P  AKY + M   ++G N ++    E+ + L + P  +
Sbjct: 290 GLFQRAIAQSGTALSSWAVSFQP--AKY-ARMLATKVGCNVSDTV--ELVECLQKKPYKE 344

Query: 296 IMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGE 355
           ++   D+   R  + +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG 
Sbjct: 345 LV-DQDIQPARYHI-AFGPVIDGD------VIPDDPQILMEQGEFLNYDIMLGVNQGEGL 396

Query: 356 YFKWIITIYNIVD 368
            F     + NIVD
Sbjct: 397 KF-----VENIVD 404


>BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 566

 Score =  149 bits (360), Expect = 3e-35
 Identities = 142/507 (28%), Positives = 221/507 (43%), Gaps = 48/507 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAK 394
             +     +P ++G NK E   F W+I +       +       +  L ++  P    AK
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAK 392

Query: 395 GIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYE 448
            +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF Y 
Sbjct: 393 ELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEFQYR 451

Query: 449 SDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYV 508
             FS   +   +      H ++L  VF    FL    S      + ++   +   ++N+ 
Sbjct: 452 PSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWANFA 503

Query: 509 RCNNPTCNKRDDPRWPPINEEELMFQV 535
           R  NP  N    P WP  N++E   Q+
Sbjct: 504 RNGNP--NGEGLPHWPEYNQKEGYLQI 528


>L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.
          Length = 566

 Score =  147 bits (356), Expect = 1e-34
 Identities = 141/507 (27%), Positives = 220/507 (43%), Gaps = 48/507 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+ KPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAK 394
             +     +P ++G NK E   F W+I +       +       +  L ++  P    AK
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAK 392

Query: 395 GIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYE 448
            +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF Y 
Sbjct: 393 ELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEFQYR 451

Query: 449 SDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYV 508
             FS   +   +      H ++L  VF    FL    S      + ++   +   ++N+ 
Sbjct: 452 PSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWANFA 503

Query: 509 RCNNPTCNKRDDPRWPPINEEELMFQV 535
           R  NP  N    P WP  N++E   Q+
Sbjct: 504 RNGNP--NGEGLPHWPEYNQKEGYLQI 528


>X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for
           bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
          Length = 745

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 374

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 375 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 434

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 435 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 483

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 484 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 517


>M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 374

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 375 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 434

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 435 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 483

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 484 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 517


>M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase
           protein.
          Length = 747

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 374

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 375 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 434

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 435 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 483

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 484 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 517


>M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipase
           protein.
          Length = 742

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 98  EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 151

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 152 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 211

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 212 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 271

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 272 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 319

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 320 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 371

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 372 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 431

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 432 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 480

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 481 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 514


>AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase
           (bile salt-stimulated lipase) protein.
          Length = 756

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 374

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 375 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 434

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 435 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 483

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 484 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 517


>AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lipase
           oncofetal isoform protein.
          Length = 612

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 78  EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 131

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 132 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 191

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 192 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 251

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 252 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 299

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 300 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 351

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 352 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 411

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 412 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 460

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 461 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 494


>AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  146 bits (355), Expect = 1e-34
 Identities = 142/454 (31%), Positives = 210/454 (46%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 374

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 375 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 434

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 435 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 483

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 484 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 517


>S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholesterol
           acyltransferase protein.
          Length = 568

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 51  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 110

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 111 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 162

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 163 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 222

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 223 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 279

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 280 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 336

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 337 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 391

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 392 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 450

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 451 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 502

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 503 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 530


>M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7
           protein.
          Length = 525

 Score =  146 bits (353), Expect = 2e-34
 Identities = 116/393 (29%), Positives = 181/393 (46%), Gaps = 37/393 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR------DITYGSITVKRKG 102
           F G+P+A PP+G+ RF              A      C         D     +   + G
Sbjct: 57  FLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFG 116

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +DV
Sbjct: 117 VSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYEDV 168

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESAG
Sbjct: 169 LVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
           A SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S+
Sbjct: 229 AISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--SE 286

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKD 342
            + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K 
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFKA 334

Query: 343 IPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRY 402
           IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   Y
Sbjct: 335 IPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANEY 389

Query: 403 FDGEPTV----DGFVKSVTDIYFQYPMIKLAQW 431
           F  + ++    D  +  + D++F  P +  A++
Sbjct: 390 FHDKHSLTEIRDSLLDLLGDVFFVVPALITARY 422


>BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.
          Length = 722

 Score =  146 bits (353), Expect = 2e-34
 Identities = 142/454 (31%), Positives = 209/454 (46%), Gaps = 67/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 101 EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMF---LGEL 272
           GESAG ASV L  LS  +KGL  +AI  SG A+ P     +P++ AK +++     +G+ 
Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274

Query: 273 GLNSTEL-TSDEIHQTLT-ELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
              +  L  +D    TL  ++PL  +     ++ Y      FVPV++ +       I  D
Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGL--EYPMLHY----VGFVPVIDGD------FIPAD 322

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V       Y+L  + 
Sbjct: 323 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKVTED---FYKLVSEF 373

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K+V    TD+ F  P  I LAQ R    SA
Sbjct: 374 TITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSA 433

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 434 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 482

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 483 SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 516


>AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 525

 Score =  146 bits (353), Expect = 2e-34
 Identities = 116/393 (29%), Positives = 181/393 (46%), Gaps = 37/393 (9%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSR------DITYGSITVKRKG 102
           F G+P+A PP+G+ RF              A      C         D     +   + G
Sbjct: 57  FLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFG 116

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA A   S        LP+LV   GG F+TGS +    G  L   +DV
Sbjct: 117 VSEDCLYLNIYAPAHADTGS-------KLPVLVWFPGGAFKTGSASI-FDGSALAAYEDV 168

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL IFG+ +      PGN   +D V  L WVQ+N + FGGDP  VTI GESAG
Sbjct: 169 LVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
           A SV  L+LS  +KGLF+KAI+ SG AI  +  +          +     G N+++  S+
Sbjct: 229 AISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASD--SE 286

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKD 342
            + + L   P  +++  +   +      SF  VV+           ++P+ L++Q   K 
Sbjct: 287 ALLRCLRTKPSKELLTLSQKTK------SFTRVVD------GAFFPNEPLDLLSQKAFKA 334

Query: 343 IPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRY 402
           IP ++G N  E  +   +     I+     + A+ L   + + +PPQ        V   Y
Sbjct: 335 IPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLH----LVANEY 389

Query: 403 FDGEPTV----DGFVKSVTDIYFQYPMIKLAQW 431
           F  + ++    D  +  + D++F  P +  A++
Sbjct: 390 FHDKHSLTEIRDSLLDLLGDVFFVVPALITARY 422


>AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  146 bits (353), Expect = 2e-34
 Identities = 143/510 (28%), Positives = 225/510 (44%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 278

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 279 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 335

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 336 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 390

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 391 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 449

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 450 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 501

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 502 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 828

 Score =  145 bits (351), Expect = 4e-34
 Identities = 132/464 (28%), Positives = 211/464 (45%), Gaps = 58/464 (12%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDIT--------------YG 94
           + G+PYA PP+G +RF              A    P CP    T                
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 95  SITVKRKGMSENCIYANVFVP----ASATLNSDELC-----EDNSL------PILVNIHG 139
            +    +  +E+C+Y NV+VP    + A    ++L      ED  +      P++V IHG
Sbjct: 129 IVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHG 188

Query: 140 GGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKW 199
           G +  G+GN  + G  L    +VIV+  NYR+ + G+LS       GN GL D +  L+W
Sbjct: 189 GSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247

Query: 200 VQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNF-YSSSP 258
           V  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +AII SG+A+ ++  +  P
Sbjct: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP 307

Query: 259 I-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVE 317
           + Y   ++D  +G   L++ ++      ++  EL   DI  A    +Y     +F PV++
Sbjct: 308 VKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA----RYH---VAFGPVID 359

Query: 318 KEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKWIITIYNIVDRYKSNPAV 376
            +      +I DDP  L+ QG   +  +++G N+ EG ++ + ++   + V     + +V
Sbjct: 360 GD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSV 413

Query: 377 ILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVKSVTDIYFQYPMIKLAQW 431
                  Y  P  + + +    F+   + D    E      V   TD  +  P +  A  
Sbjct: 414 SNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 432 RILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVF 475
                S PTYFY F Y    S+ K A    +   AH +++ YVF
Sbjct: 474 HARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYVF 511


>BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.
          Length = 828

 Score =  144 bits (350), Expect = 6e-34
 Identities = 132/464 (28%), Positives = 211/464 (45%), Gaps = 58/464 (12%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDIT--------------YG 94
           + G+PYA PP+G +RF              A    P CP    T                
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPYWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 95  SITVKRKGMSENCIYANVFVP----ASATLNSDELC-----EDNSL------PILVNIHG 139
            +    +  +E+C+Y NV+VP    + A    ++L      ED  +      P++V IHG
Sbjct: 129 IVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHG 188

Query: 140 GGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKW 199
           G +  G+GN  + G  L    +VIV+  NYR+ + G+LS       GN GL D +  L+W
Sbjct: 189 GSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247

Query: 200 VQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNF-YSSSP 258
           V  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +AII SG+A+ ++  +  P
Sbjct: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP 307

Query: 259 I-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVE 317
           + Y   ++D  +G   L++ ++      ++  EL   DI  A    +Y     +F PV++
Sbjct: 308 VKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA----RYH---VAFGPVID 359

Query: 318 KEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKWIITIYNIVDRYKSNPAV 376
            +      +I DDP  L+ QG   +  +++G N+ EG ++ + ++   + V     + +V
Sbjct: 360 GD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSV 413

Query: 377 ILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVKSVTDIYFQYPMIKLAQW 431
                  Y  P  + + +    F+   + D    E      V   TD  +  P +  A  
Sbjct: 414 SNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 432 RILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVF 475
                S PTYFY F Y    S+ K A    +   AH +++ YVF
Sbjct: 474 HARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYVF 511


>S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipase
           protein.
          Length = 742

 Score =  144 bits (349), Expect = 7e-34
 Identities = 139/454 (30%), Positives = 205/454 (45%), Gaps = 66/454 (14%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSG------NRDLH-GPELL 157
           E+C+Y N++VP      S +L      P+++ I+GG F  GSG      N  L+ G E+ 
Sbjct: 98  EDCLYLNIWVPQGRKQVSRDL------PVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 151

Query: 158 MLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTIL 217
              +VIVV FNYR+   G+LS     +PGN GLRD    + WV+RN   FGGDP  +T+ 
Sbjct: 152 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 211

Query: 218 GESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYSSSPIY-AKYISDMFLGELG-- 273
           GESAG ASV L  LS  +KGL   AI  SG A+ P     +P++ AK +++     +G  
Sbjct: 212 GESAGGASVSLQTLSPYNKGLIRAAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 271

Query: 274 ---LNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
                  ++T         ++PL  +     ++ Y      FVPV++++       I  D
Sbjct: 272 ARMAQCLKVTDPAAVTVAYKVPLAGL--EYPMLHY----VGFVPVIDED------FIPAD 319

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQE 390
           PI L       DI  + G N  +G  F  I    ++    K N  V  +    Y+L  + 
Sbjct: 320 PINLYANAA--DIDYIAGTNNMDGHIFASI----DMPAINKGNKKV--TEEDFYKLVSEF 371

Query: 391 ASAKGIFVGKRYFD-------GEPTVDGFVKSV----TDIYFQYPM-IKLAQWRILLNSA 438
              KG+   K  FD        +P+ +   K V    TD+ F  P  I LAQ R    SA
Sbjct: 372 TITKGLRGAKTTFDVYTESWAQDPSQENKKKIVVDFETDVLFLVPTEIALAQHRANAKSA 431

Query: 439 PTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPP--KTRDDQM 496
            TY Y FS+ S   +  +  W+   G  H +D+ YVF      G   + P   + +D  +
Sbjct: 432 KTYAYLFSHPSRMPVYPK--WV---GADHADDIQYVF------GKPFATPTGYRPQDRTV 480

Query: 497 RDWMSTLFSNYVRCNNPTCNKRDDP-RWPPINEE 529
              M   ++N+ +  +P       P  W P   E
Sbjct: 481 FKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTE 514


>L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.
          Length = 568

 Score =  144 bits (349), Expect = 7e-34
 Identities = 142/510 (27%), Positives = 224/510 (43%), Gaps = 53/510 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+ KPP+G  RF              A    P C   P        +   RK    
Sbjct: 51  FLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 110

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 111 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 162

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 163 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 222

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELT 280
           AG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  T
Sbjct: 223 AGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--T 279

Query: 281 SDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITL 334
           S  +   L +   ++++     +++   L+  +    +E       + D       P  L
Sbjct: 280 SAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEEL 336

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEA 391
             +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P   
Sbjct: 337 QAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVC 391

Query: 392 SAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEF 445
            AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF
Sbjct: 392 IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEF 450

Query: 446 SYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFS 505
            Y   FS   +   +      H ++L  VF    FL    S      + ++   +   ++
Sbjct: 451 QYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWA 502

Query: 506 NYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           N+ R  NP  N    P WP  N++E   Q+
Sbjct: 503 NFARNGNP--NGEGLPHWPEYNQKEGYLQI 530


>BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.
          Length = 587

 Score =  143 bits (346), Expect = 2e-33
 Identities = 142/511 (27%), Positives = 230/511 (45%), Gaps = 74/511 (14%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 101 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 160

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 161 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 212

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 213 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 272

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 273 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 327

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 328 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 375

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 376 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 432

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 433 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQ-- 485

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
                  +WL      H++   +V  T               ++Q+   M   ++N+ R 
Sbjct: 486 ------PSWLKNIRPPHMK-ADHVKFT-------------EEEEQLSRKMMKYWANFARN 525

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 526 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 554


>BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.
          Length = 586

 Score =  143 bits (346), Expect = 2e-33
 Identities = 142/511 (27%), Positives = 230/511 (45%), Gaps = 74/511 (14%)

Query: 48  SFQGIPYAKPPVGARRFXX-------XXXXXXXXXXFYAYEEGPACPSRDITYGSITVKR 100
           +F GIP+AKPP+G  RF                       ++  A  S  ++  ++T   
Sbjct: 100 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 159

Query: 101 KGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             MSE+C+Y +++ PA +        E ++LP++V IHGG    G  +    G  L  L+
Sbjct: 160 DSMSEDCLYLSIYTPAHSH-------EGSNLPVMVWIHGGALVFGMASL-YDGSMLAALE 211

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL + G+ S       GN G  D V  L+WVQ+N   FGG+P RVTI GES
Sbjct: 212 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 271

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTA-IPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           AG  SV  L++S  S+GLF+ AI+ SG A +P   +SS   A  IS + +  L     ++
Sbjct: 272 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASS---ADVISTV-VANLSA-CDQV 326

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGV 339
            S+ +   L     ++I+  N   +   G+   V             +   P  L+    
Sbjct: 327 DSEALVGCLRGKSKEEILAINKPFKMIPGVVDGV------------FLPRHPQELLASAD 374

Query: 340 GKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYK-----SNPAVILSPRLAYELPPQEAS- 392
            + +P ++G N +E   F W+I  +  I D  K     ++ A +        LPP     
Sbjct: 375 FQPVPSIVGVNNNE---FGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDL 431

Query: 393 AKGIFVGKRYFDGEP-TVDG-FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
            +  ++G    +G+P T+   F + + D  F  P +++A ++   + AP YFYEF ++  
Sbjct: 432 LREEYIGD---NGDPQTLQAQFQEMMADSMFVIPALQVAHFQ--CSRAPVYFYEFQHQ-- 484

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
                  +WL      H++   +V  T               ++Q+   M   ++N+ R 
Sbjct: 485 ------PSWLKNIRPPHMK-ADHVKFT-------------EEEEQLSRKMMKYWANFARN 524

Query: 511 NNPTCNKRDDPRWPPINEEELMFQVIKEPNV 541
            NP  N    P WP  ++EE   Q+  +P V
Sbjct: 525 GNP--NGEGLPHWPLFDQEEQYLQLNLQPAV 553


>AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 571

 Score =  143 bits (346), Expect = 2e-33
 Identities = 135/528 (25%), Positives = 234/528 (44%), Gaps = 54/528 (10%)

Query: 31  GPVCGREESANKNTKYFS-FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC--- 86
           G V GR+       +  + F GIP+A+PP+G  RF              A    P C   
Sbjct: 41  GRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQD 100

Query: 87  -PSRDITYGSITVKRK--GMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQ 143
             S + +   +  K++   +SE+C+  NV+ PA     S         P++V +HGG   
Sbjct: 101 VESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGR-------PVMVWVHGGALI 153

Query: 144 TGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRN 203
           TG+      G  L    DV+VV   YRL + G+ S      PGN G  D+V  L+WVQ N
Sbjct: 154 TGAAT-SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQEN 212

Query: 204 AKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGT-AIPNFYSSSPIYAK 262
              FGGD   VT+ G SAG + +  L+LS  + GLF++AI  SG    P    S P    
Sbjct: 213 IAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHP---W 269

Query: 263 YISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHD 322
            ++      L  +S+  +  E+ Q L +   ++++ +         L + +  +  +G  
Sbjct: 270 PLAQKIANTLACSSS--SPAEMVQCLQQKEGEELVLSKK-------LKNTIYPLTVDG-- 318

Query: 323 YTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYFKWIITI-YNIVDRY----KSNPAVI 377
              +    P  L+ +     +P LMG N  E   F W+I   + ++D      + +   I
Sbjct: 319 --TVFPKSPKELLKEKPFHSVPFLMGVNNHE---FSWLIPRGWGLLDTMEQMSREDMLAI 373

Query: 378 LSPRL-AYELPPQ-EASAKGIFVGKRYFDGEPTVDGFVKSVTDIYFQYPMIKLAQWRILL 435
            +P L + ++PP+   +    ++G    D +     F + + D++   P +  +++ +  
Sbjct: 374 STPVLTSLDVPPEMMPTVIDEYLGSN-SDAQAKCQAFQEFMGDVFINVPTVSFSRY-LRD 431

Query: 436 NSAPTYFYEFSYE-SDFSITKRANWLSYKGTAHVEDLTYVFHTTTFL--GSQVSVPPKTR 492
           + +P +FYEF +  S F+  K A W+      H  +  +VF     +   S+++ P  T 
Sbjct: 432 SGSPVFFYEFQHRPSSFAKIKPA-WVK---ADHGAEGAFVFGGPFLMDESSRLAFPEATE 487

Query: 493 DD-QMRDWMSTLFSNYVRCNNPTCNKRDDPRWPPINEEELMFQVIKEP 539
           ++ Q+   M   ++++ R  +P  N +  P WP  N+ E   ++   P
Sbjct: 488 EEKQLSLTMMAQWTHFARTGDP--NSKALPPWPQFNQAEQYLEINPVP 533


>AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester
           hydrolase protein.
          Length = 567

 Score =  142 bits (345), Expect = 2e-33
 Identities = 144/511 (28%), Positives = 227/511 (44%), Gaps = 55/511 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDITYGSIT----VKRKG-- 102
           F GIP+AKPP+G  R               A    P C +RD   G +       RK   
Sbjct: 50  FLGIPFAKPPLGPLRSTPPQPAEPWSFVKNATSYPPMC-TRDPKAGQLLSELFTNRKENI 108

Query: 103 ---MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLML 159
              +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   
Sbjct: 109 PLKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAH 160

Query: 160 KDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGE 219
           ++V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GE
Sbjct: 161 ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGE 220

Query: 220 SAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           SAG  SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  
Sbjct: 221 SAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT-- 277

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPIT 333
           TS  +   L +   ++++     +++   L+  +    +E       + D       P  
Sbjct: 278 TSAVMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEE 334

Query: 334 LINQGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQE 390
           L  +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P  
Sbjct: 335 LQAERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLV 389

Query: 391 ASAKGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
             AK +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YE
Sbjct: 390 CIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYE 448

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLF 504
           F Y   FS   +   +      H ++L  VF    FL    S      + ++   +   +
Sbjct: 449 FQYRPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFW 500

Query: 505 SNYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           +N+ R  NP  N    P WP  N++E   Q+
Sbjct: 501 ANFARNGNP--NGEGLPHWPEYNQKEGYLQI 529


>BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.
          Length = 568

 Score =  142 bits (344), Expect = 3e-33
 Identities = 132/525 (25%), Positives = 228/525 (43%), Gaps = 51/525 (9%)

Query: 31  GPVCGREESANKNTKYFS-FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC--- 86
           G V GR+       +  + F GIP+A+PP+G  RF              A    P C   
Sbjct: 41  GRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQD 100

Query: 87  -PSRDITYGSITVKRK--GMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQ 143
             S + +   +  K++   +SE+C+  NV+ PA     S         P++V +HGG   
Sbjct: 101 VESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGR-------PVMVWVHGGALI 153

Query: 144 TGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRN 203
           TG+      G  L    DV+VV   YRL + G+ S      PGN G  D+V  L+WVQ N
Sbjct: 154 TGAAT-SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQEN 212

Query: 204 AKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGT-AIPNFYSSSPIYAK 262
              FGGD   VT+ G SAG + +  L+LS  + GLF++AI  SG    P    S P    
Sbjct: 213 IAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHP---W 269

Query: 263 YISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHD 322
            ++      L  +S+  +  E+ Q L +   ++++ +         L + +  +  +G  
Sbjct: 270 PLAQKIANTLACSSS--SPAEMVQCLQQKEGEELVLSKK-------LKNTIYPLTVDG-- 318

Query: 323 YTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYFKWIITI-YNIVDRY----KSNPAVI 377
              +    P  L+ +     +P LMG N  E   F W+I   + ++D      + +   I
Sbjct: 319 --TVFPKSPKELLKEKPFHSVPFLMGVNNHE---FSWLIPRGWGLLDTMEQMSREDMLAI 373

Query: 378 LSPRL-AYELPPQ-EASAKGIFVGKRYFDGEPTVDGFVKSVTDIYFQYPMIKLAQWRILL 435
            +P L + ++PP+   +    ++G    D +     F + + D++   P +  +++ +  
Sbjct: 374 STPVLTSLDVPPEMMPTVIDEYLGSN-SDAQAKCQAFQEFMGDVFINVPTVSFSRY-LRD 431

Query: 436 NSAPTYFYEFSYE-SDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDD 494
           + +P +FYEF +  S F+  K A W+      H  +  +VF     +     +     + 
Sbjct: 432 SGSPVFFYEFQHRPSSFAKIKPA-WVK---ADHGAEGAFVFGGPFLMDESSRLEATEEEK 487

Query: 495 QMRDWMSTLFSNYVRCNNPTCNKRDDPRWPPINEEELMFQVIKEP 539
           Q+   M   ++++ R  +P  N +  P WP  N+ E   ++   P
Sbjct: 488 QLSLTMMAQWTHFARTGDP--NSKALPPWPQFNQAEQYLEINPVP 530


>AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HNL3
           protein.
          Length = 828

 Score =  142 bits (344), Expect = 3e-33
 Identities = 131/464 (28%), Positives = 210/464 (45%), Gaps = 58/464 (12%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDIT--------------YG 94
           + G+PYA PP+G +RF              A    P CP    T                
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 95  SITVKRKGMSENCIYANVFVP----ASATLNSDELC-----EDNSL------PILVNIHG 139
            +    +  +E+C+Y NV+VP    + A    ++L      ED  +      P++V IHG
Sbjct: 129 IVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHG 188

Query: 140 GGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKW 199
           G +  G+GN  + G       +VIV+  NYR+ + G+LS       GN GL D +  L+W
Sbjct: 189 GSYMEGTGNM-IDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247

Query: 200 VQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNF-YSSSP 258
           V  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +AII SG+A+ ++  +  P
Sbjct: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP 307

Query: 259 I-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVE 317
           + Y   ++D  +G   L++ ++      ++  EL   DI  A    +Y     +F PV++
Sbjct: 308 VKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA----RYH---VAFGPVID 359

Query: 318 KEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKWIITIYNIVDRYKSNPAV 376
            +      +I DDP  L+ QG   +  +++G N+ EG ++ + ++   + V     + +V
Sbjct: 360 GD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSV 413

Query: 377 ILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVKSVTDIYFQYPMIKLAQW 431
                  Y  P  + + +    F+   + D    E      V   TD  +  P +  A  
Sbjct: 414 SNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 432 RILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVF 475
                S PTYFY F Y    S+ K A    +   AH +++ YVF
Sbjct: 474 HARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYVF 511


>AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.
          Length = 679

 Score =  142 bits (344), Expect = 3e-33
 Identities = 121/400 (30%), Positives = 194/400 (48%), Gaps = 31/400 (7%)

Query: 124 ELCEDNSL-PILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASH 182
           ++ E NS  P++V IHGG +  G+GN  + G  L    +VIV+  NYRL I G+LS    
Sbjct: 21  DIHEQNSKKPVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITINYRLGILGFLSTGDQ 79

Query: 183 KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKA 242
              GN GL D +  L+W++ N   FGGDPKRVTI G  AGA+ V LL LS  S+GLF KA
Sbjct: 80  AAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKA 139

Query: 243 IIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDV 302
           II SGTA+ + ++ +   AKY + +   ++G N  + T+D +     +   + I +    
Sbjct: 140 IIQSGTALSS-WAVNYQPAKY-TRILADKVGCNMLD-TTDMVECLKNKNYKELIQQTITP 196

Query: 303 VQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYFKWIIT 362
             Y     +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG   K++  
Sbjct: 197 ATYH---IAFGPVIDGD------VIPDDPQILMEQGEFLNYDIMLGVNQGEG--LKFVDG 245

Query: 363 IYNIVDRYKSNP---AVILSPRLAYELPPQEASAKGI--FVGKRYFDGE-PTV--DGFVK 414
           I +  D    N    +V       Y  P  + + +    F+   + D E P       V 
Sbjct: 246 IVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVA 305

Query: 415 SVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYV 474
             TD  +  P +  A       S PTYFY F +     +  + +W     +AH +++ YV
Sbjct: 306 LFTDHQWVAPAVATADLHAQYGS-PTYFYAFYHHCQSEM--KPSWAD---SAHGDEVPYV 359

Query: 475 FHTTTFLGSQVSVPPKTRDDQMRD-WMSTLFSNYVRCNNP 513
           F       +++     +++D M    + T ++N+ +  +P
Sbjct: 360 FGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDP 399


>BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.
          Length = 454

 Score =  141 bits (342), Expect = 5e-33
 Identities = 109/332 (32%), Positives = 164/332 (49%), Gaps = 34/332 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRD-----ITYGSITVKRKGM 103
           F G+P+++PP+G  RF              A    P C           Y S   + K +
Sbjct: 14  FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWL 73

Query: 104 --SENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKD 161
             SE+C+Y NV+ PA A         D  LP++V   GG F  G+ +    G +L   + 
Sbjct: 74  RFSEDCLYLNVYAPARAP-------GDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREK 125

Query: 162 VIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESA 221
           V++V   +RL IFG+LS       GN GL D +  L+WVQ N   FGGDP  VT+ G+SA
Sbjct: 126 VVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSA 185

Query: 222 GAASVHLLMLSRASKGLFNKAIIMSGTAIPN-FYSSSPI-YAKYISDMFLGELGLNSTEL 279
           GA S+  LM+S  + GLF++AI  SGTA+   F +S+P+  AK ++   L     NST++
Sbjct: 186 GAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVA--HLAGCNHNSTQI 243

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIID-----DDPITL 334
               +   L  L    +MR ++ +++     +F    E+     + ++D     DDP+ L
Sbjct: 244 ----LVNCLRALSGTKVMRVSNKMRFLQ--LNFQRDPEEIIWSMSPVVDGVVIPDDPLVL 297

Query: 335 INQGVGKDIPLLMGFNKDEGEYFKWIITIYNI 366
           + QG    +P L+G N  E   F W++  YNI
Sbjct: 298 LTQGKVSSVPYLLGVNNLE---FNWLLP-YNI 325


>AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase
           hBr2 protein.
          Length = 565

 Score =  140 bits (340), Expect = 9e-33
 Identities = 142/512 (27%), Positives = 223/512 (43%), Gaps = 59/512 (11%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDITYGSIT----VKRKG-- 102
           F G+P+AKPP+G  RF                   P C S+D   G +       RK   
Sbjct: 50  FLGVPFAKPPLGPLRFAPPQAAEPWNFVKNTTSYPPMC-SQDAVGGQVLSELFTNRKDNI 108

Query: 103 ---MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLML 159
               SE+C+Y N++ PA  T NS        LP++V IHGGG   G G     G  L   
Sbjct: 109 PLKFSEDCLYLNIYTPADLTKNS-------RLPVMVWIHGGGLVVG-GASTYDGLALSAH 160

Query: 160 KDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGE 219
           ++V+VV   YRL I+G+ S       GN G  D +  L+WVQ N   FGG+P  VTI GE
Sbjct: 161 ENVVVVTIQYRLGIWGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGE 220

Query: 220 SAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTEL 279
           SAG  SV +L+LS  +K LF++AI  SG A+        +  K  +       G  ST  
Sbjct: 221 SAGGESVSVLVLSPLAKNLFHRAISESGVALTAALVKKDM--KDTAQQIAVFAGCKST-- 276

Query: 280 TSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD------PIT 333
           TS  +   L +   D+++  +  +++    T  +    +E + +   + D       P  
Sbjct: 277 TSAVLVHCLRQKTEDELLEVSLKLKF---FTLDLLGDPRESYPFLPTVVDGVLLPKMPQE 333

Query: 334 LINQGVGKDIPLLMGFNKDEGEYFKWIITI---YNI-VDRYKSNPAVILSPRLAYELP-- 387
           ++ +     +P ++G NK E   F W++ +   Y +  D+     A  L  + +Y +   
Sbjct: 334 ILAEKKFNSVPYIIGINKQE---FGWLLPMMMGYPLSEDKLDQKTASSLLWK-SYPIANI 389

Query: 388 PQEASAKGIFVGKRYFDG--EPTVDG--FVKSVTDIYFQYPMIKLAQWRILLNSAPTYFY 443
           P+E +       ++Y  G  +P      F+  + D+ F  P + +A+       APTY Y
Sbjct: 390 PEELTP---LASEKYLGGTDDPVKKKALFLDMLGDVVFGVPSVTVARHH-RDAGAPTYMY 445

Query: 444 EFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTL 503
           EF Y   FS   +    +  G  H ++L  VF      G          + ++   M  L
Sbjct: 446 EFQYHPSFSSDMKPQ--TVVGD-HGDELFSVFGAPFLKGG-----ASEEEIRLSKMMMKL 497

Query: 504 FSNYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           ++N+ R  NP    +    WP  +++E   Q+
Sbjct: 498 WANFARSGNPM--GKGCSSWPAYDQKEGYLQI 527


>BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein
           protein.
          Length = 351

 Score =  137 bits (332), Expect = 8e-32
 Identities = 91/271 (33%), Positives = 144/271 (53%), Gaps = 32/271 (11%)

Query: 104 SENCIYANVFVP----ASATLNSDELC-----EDNSL------PILVNIHGGGFQTGSGN 148
           +E+C+Y NV+VP    + A    ++L      ED  +      P++V IHGG +  G+GN
Sbjct: 21  NEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGN 80

Query: 149 RDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFG 208
             + G  L    +VIV+  NYR+ + G+LS       GN GL D +  L+WV  N   FG
Sbjct: 81  M-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 139

Query: 209 GDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNF-YSSSPI-YAKYISD 266
           GDP+R+T+ G   GA+ V LL LS  S+GLF +AII SG+A+ ++  +  P+ Y   ++D
Sbjct: 140 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVEYTSLLAD 199

Query: 267 MFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRI 326
             +G   L++ ++      ++  EL   DI  A    +Y     +F PV++ +      +
Sbjct: 200 K-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA----RYH---VAFGPVIDGD------V 245

Query: 327 IDDDPITLINQGVGKDIPLLMGFNKDEGEYF 357
           I DDP  L+ QG   +  +++G N+ EG  F
Sbjct: 246 IPDDPEILMEQGEFLNYDIMLGVNQGEGLKF 276


>X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage
           serine-esterase 1 protein.
          Length = 503

 Score =  136 bits (330), Expect = 1e-31
 Identities = 125/445 (28%), Positives = 201/445 (45%), Gaps = 40/445 (8%)

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   ++V
Sbjct: 49  LSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHENV 100

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GESAG
Sbjct: 101 VVVTIQYRLGIWGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAG 160

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
             SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  TS 
Sbjct: 161 GESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--TSA 217

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITLIN 336
            +   L +   ++++     +++   L+  +    +E       + D       P  L  
Sbjct: 218 VMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQA 274

Query: 337 QGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGI 396
           +     +P ++G NK E   F W+I +       +       +  L ++  P    AK +
Sbjct: 275 ERNFHTVPYMVGINKQE---FGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL 331

Query: 397 F--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESD 450
                ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF Y   
Sbjct: 332 IPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEFQYRPS 390

Query: 451 FSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRC 510
           FS   +   +      H ++L  VF    FL    S      + ++   +   ++N+ R 
Sbjct: 391 FSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWANFARN 442

Query: 511 NNPTCNKRDDPRWPPINEEELMFQV 535
            NP  N    P WP  N++E   Q+
Sbjct: 443 GNP--NGEGLPHWPEYNQKEGYLQI 465


>AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related
           acetylcholinesterase protein.
          Length = 526

 Score =  136 bits (329), Expect = 2e-31
 Identities = 90/255 (35%), Positives = 134/255 (52%), Gaps = 18/255 (7%)

Query: 1   MFVLLLLILGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVG 60
           + +LLL +LG  + AE   +  ++LV +  G + G            +F GIP+A+PP+G
Sbjct: 17  LLLLLLWLLGGGVGAEG-REDAELLVTVRGGRLRGIRLKT-PGGPVSAFLGIPFAEPPMG 74

Query: 61  ARRFXXXXXXXXXXXXFYAYEEGPACPSR-DITYGSITVKR-----KGMSENCIYANVFV 114
            RRF              A      C    D  Y            + +SE+C+Y NV+ 
Sbjct: 75  PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWT 134

Query: 115 PASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLH-GPELLMLKDVIVVNFNYRLAI 173
           P     +          P+LV I+GGGF +G+ + D++ G  L+  +  ++V+ NYR+  
Sbjct: 135 PYPRPTSPT--------PVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGA 186

Query: 174 FGYLSL-ASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLS 232
           FG+L+L  S + PGN GL D    L+WVQ N   FGGDP  VT+ GESAGAASV + +LS
Sbjct: 187 FGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 246

Query: 233 RASKGLFNKAIIMSG 247
             S+GLF++A++ SG
Sbjct: 247 PPSRGLFHRAVLQSG 261


>AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 848

 Score =  135 bits (327), Expect = 3e-31
 Identities = 107/361 (29%), Positives = 177/361 (49%), Gaps = 29/361 (8%)

Query: 123 DELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASH 182
           +++ +  + P++V IHGG +  G+GN  + G  L    +VIV+  NYR+ + G+LS    
Sbjct: 192 EDIRDSGAKPVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQ 250

Query: 183 KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKA 242
              GN GL D +  L+WV  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +A
Sbjct: 251 AAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRA 310

Query: 243 IIMSGTAIPNF-YSSSPI-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRAN 300
           II SG+A+ ++  +  P+ Y   ++D  +G   L++ ++      ++  EL   DI  A 
Sbjct: 311 IIQSGSALSSWAVNYQPVKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA- 368

Query: 301 DVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKW 359
              +Y     +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG ++ + 
Sbjct: 369 ---RYH---VAFGPVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEG 416

Query: 360 IITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVK 414
           ++   + V     + +V       Y  P  + + +    F+   + D    E      V 
Sbjct: 417 VVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVA 476

Query: 415 SVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYV 474
             TD  +  P +  A       S PTYFY F Y    S+ K A    +   AH +++ YV
Sbjct: 477 LFTDHQWVEPSVVTADLHARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYV 530

Query: 475 F 475
           F
Sbjct: 531 F 531


>AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HNL3s
           protein.
          Length = 558

 Score =  135 bits (327), Expect = 3e-31
 Identities = 107/361 (29%), Positives = 177/361 (49%), Gaps = 29/361 (8%)

Query: 123 DELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASH 182
           +++ +  + P++V IHGG +  G+GN  + G  L    +VIV+  NYR+ + G+LS    
Sbjct: 192 EDIRDSGAKPVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQ 250

Query: 183 KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKA 242
              GN GL D +  L+WV  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +A
Sbjct: 251 AAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRA 310

Query: 243 IIMSGTAIPNF-YSSSPI-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRAN 300
           II SG+A+ ++  +  P+ Y   ++D  +G   L++ ++      ++  EL   DI  A 
Sbjct: 311 IIQSGSALSSWAVNYQPVKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA- 368

Query: 301 DVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKW 359
              +Y     +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG ++ + 
Sbjct: 369 ---RYH---VAFGPVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEG 416

Query: 360 IITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVK 414
           ++   + V     + +V       Y  P  + + +    F+   + D    E      V 
Sbjct: 417 VVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVA 476

Query: 415 SVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYV 474
             TD  +  P +  A       S PTYFY F Y    S+ K A    +   AH +++ YV
Sbjct: 477 LFTDHQWVEPSVVTADLHARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYV 530

Query: 475 F 475
           F
Sbjct: 531 F 531


>AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.
          Length = 682

 Score =  135 bits (327), Expect = 3e-31
 Identities = 107/361 (29%), Positives = 177/361 (49%), Gaps = 29/361 (8%)

Query: 123 DELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASH 182
           +++ +  + P++V IHGG +  G+GN  + G  L    +VIV+  NYR+ + G+LS    
Sbjct: 26  EDIRDSGAKPVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQ 84

Query: 183 KIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKA 242
              GN GL D +  L+WV  N   FGGDP+R+T+ G   GA+ V LL LS  S+GLF +A
Sbjct: 85  AAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRA 144

Query: 243 IIMSGTAIPNF-YSSSPI-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRAN 300
           II SG+A+ ++  +  P+ Y   ++D  +G   L++ ++      ++  EL   DI  A 
Sbjct: 145 IIQSGSALSSWAVNYQPVKYTSLLADK-VGCNVLDTVDMVDCLRQKSAKELVEQDIQPA- 202

Query: 301 DVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEG-EYFKW 359
              +Y     +F PV++ +      +I DDP  L+ QG   +  +++G N+ EG ++ + 
Sbjct: 203 ---RYH---VAFGPVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEG 250

Query: 360 IITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGI--FVGKRYFD---GEPTVDGFVK 414
           ++   + V     + +V       Y  P  + + +    F+   + D    E      V 
Sbjct: 251 VVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVA 310

Query: 415 SVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYV 474
             TD  +  P +  A       S PTYFY F Y    S+ K A    +   AH +++ YV
Sbjct: 311 LFTDHQWVEPSVVTADLHARYGS-PTYFYAF-YHHCQSLMKPA----WSDAAHGDEVPYV 364

Query: 475 F 475
           F
Sbjct: 365 F 365


>AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 545

 Score =  135 bits (326), Expect = 5e-31
 Identities = 95/270 (35%), Positives = 143/270 (52%), Gaps = 27/270 (10%)

Query: 104 SENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVI 163
           SE+C+Y NV+ PA A         D  LP++V   GG F  G+ +    G +L   + V+
Sbjct: 217 SEDCLYLNVYAPARAP-------GDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREKVV 268

Query: 164 VVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGA 223
           +V   +RL IFG+LS       GN GL D +  L+WVQ N   FGGDP  VT+ G+SAGA
Sbjct: 269 LVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGA 328

Query: 224 ASVHLLMLSRASKGLFNKAIIMSGTAIPN-FYSSSPI-YAKYISDMFLGELGLNSTELTS 281
            S+  LM+S  + GLF++AI  SGTA+   F +S+P+  AK ++   L     NST++  
Sbjct: 329 MSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVA--HLAGCNHNSTQI-- 384

Query: 282 DEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIID-----DDPITLIN 336
             +   L  L    +MR ++ +++     +F    E+     + ++D     DDP+ L+ 
Sbjct: 385 --LVNCLRALSGTKVMRVSNKMRFLQ--LNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLT 440

Query: 337 QGVGKDIPLLMGFNKDEGEYFKWIITIYNI 366
           QG    +P L+G N  E   F W++  YNI
Sbjct: 441 QGKVSSVPYLLGVNNLE---FNWLLP-YNI 466


>AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase
           hBr3 protein.
          Length = 567

 Score =  134 bits (325), Expect = 6e-31
 Identities = 140/500 (28%), Positives = 217/500 (43%), Gaps = 56/500 (11%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACPSRDITY---GSITVKRK---- 101
           F G+P+AKPP+G+ RF                   P C    + +     +   RK    
Sbjct: 50  FLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGWQVLSELFTNRKENIP 109

Query: 102 -GMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
              SE+C+Y N++ PA  T NS        LP++V IHGGG   G G     G  L   +
Sbjct: 110 LQFSEDCLYLNIYTPADLTKNS-------RLPVMVWIHGGGLVVG-GASTYDGLALSAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNST--- 277
           AG  SV +L+LS  +K LF++AI  SG ++     ++ +  K I+ +     G  +T   
Sbjct: 222 AGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDV--KPIAGLVATLSGCKTTTSA 279

Query: 278 -------ELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDD 330
                  + T DE+ +T  +L L  +    D++        F+P V  +G     ++   
Sbjct: 280 VMVHCLRQKTEDELLETSLKLNLFKL----DLLGNPKESYPFLPTV-IDG----VVLPKA 330

Query: 331 PITLINQGVGKDIPLLMGFNKDEGEYFKWII-TIYNIVDRYKSNPAVILSPRLAYELPPQ 389
           P  ++ +     +P ++G NK E   F WII T+               +  L    P  
Sbjct: 331 PEEILAEKSFSTVPYIVGINKQE---FGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTL 387

Query: 390 EASAKGI-FVGKRYFDGEPTV----DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYE 444
           + S   I  V ++Y  G   +    D F   + D+ F  P + +++       A TY YE
Sbjct: 388 KISENMIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVPSVIVSRSH-RDAGASTYMYE 446

Query: 445 FSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLF 504
           F Y   F +++  +  +  G  H +++  VF  + FL    S      +  +   +   +
Sbjct: 447 FEYRPSF-VSRHEDPKAVIGD-HGDEIFSVF-GSPFLKDGAS----EEETNLSKMVMKFW 499

Query: 505 SNYVRCNNPTCNKRDDPRWP 524
           +N+ R  NP  N    P WP
Sbjct: 500 ANFARNGNP--NGGGLPHWP 517


>M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.
          Length = 507

 Score =  134 bits (323), Expect = 1e-30
 Identities = 126/448 (28%), Positives = 205/448 (45%), Gaps = 45/448 (10%)

Query: 103 MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDV 162
           +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   ++V
Sbjct: 52  LSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHENV 103

Query: 163 IVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAG 222
           +VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GESAG
Sbjct: 104 VVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAG 163

Query: 223 AASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSD 282
             SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  TS 
Sbjct: 164 GESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--TSA 220

Query: 283 EIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDD------DPITLIN 336
            +   L +   ++++     +++   L+  +    +E       + D       P  L  
Sbjct: 221 VMVHCLRQKTEEELLETTLKMKF---LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQA 277

Query: 337 QGVGKDIPLLMGFNKDEGEYFKWIITIYNI---VDRYKSNPAVILSPRLAYELPPQEASA 393
           +     +P ++G NK E   F W+I +  +   +   + +    +S  L ++  P    A
Sbjct: 278 ERNFHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMS--LLWKSYPLVCIA 332

Query: 394 KGIF--VGKRYFDG-EPTV---DGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSY 447
           K +     ++Y  G + TV   D F+  + D+ F  P + +A+       APTY YEF Y
Sbjct: 333 KELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEFQY 391

Query: 448 ESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNY 507
              FS   +   +      H ++L  VF    FL    S      + ++   +   ++N+
Sbjct: 392 RPSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWANF 443

Query: 508 VRCNNPTCNKRDDPRWPPINEEELMFQV 535
            R  NP  N    P WP  N++E   Q+
Sbjct: 444 ARNGNP--NGEGLPHWPEYNQKEGYLQI 469


>M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.
          Length = 454

 Score =  132 bits (318), Expect = 4e-30
 Identities = 129/447 (28%), Positives = 207/447 (46%), Gaps = 47/447 (10%)

Query: 105 ENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIV 164
           E+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   ++V+V
Sbjct: 1   EHCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHENVVV 52

Query: 165 VNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAA 224
           V   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GESAG  
Sbjct: 53  VTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGE 112

Query: 225 SVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEI 284
           SV +L+LS  +K LF++AI  SG A+ +         K +++      G  +T  TS  +
Sbjct: 113 SVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTT--TSAAM 169

Query: 285 HQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIID-----DDPITLINQGV 339
              L +   ++++     +   + L ++    ++E      +ID       P  L  +  
Sbjct: 170 VHCLRQKTEEELLETTLKIG-NSYLWTY-RETQRESTLLGTVIDGMLLLKTPEELQRERN 227

Query: 340 GKDIPLLMGFNKDEGEYFKWIITI----YNIVD---RYKSNPAVILSP----RLAYELPP 388
              +P ++G NK E   F W+I +    Y + +     K+  +++ SP     +A EL P
Sbjct: 228 FHTVPYMVGINKQE---FGWLIPMQLMSYPLSEGQLDQKTAMSLLGSPIPLFAIAKELIP 284

Query: 389 QEASAKGIFVGKRYFDGEPTVDGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYE 448
            EA+ K  ++G    D     D  +  + D+ F  P + +A+       APTY YEF Y 
Sbjct: 285 -EATEK--YLGGT-DDTVKKKDLILDLIADVMFGVPSVIVAR-NHRDAGAPTYMYEFQYR 339

Query: 449 SDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYV 508
             FS   +   +      H ++L  VF    FL    S      + ++   +   ++N+ 
Sbjct: 340 PSFSSDMKPKTVI---GDHGDELFSVF-GAPFLKEGAS----EEEIRLSKMVMKFWANFA 391

Query: 509 RCNNPTCNKRDDPRWPPINEEELMFQV 535
           R  NP  N +  P WP  N++E   Q+
Sbjct: 392 RNGNP--NGKGLPHWPEYNQKEGYLQI 416


>AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase
           hBr1 protein.
          Length = 429

 Score =  131 bits (316), Expect = 7e-30
 Identities = 81/210 (38%), Positives = 108/210 (51%), Gaps = 16/210 (7%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRKG--- 102
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 50  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 109

Query: 103 --MSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLK 160
             +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   +
Sbjct: 110 LKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAHE 161

Query: 161 DVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGES 220
           +V+VV   YRL I+G+ S       GN G  D V  L+WVQ N   FGG+P  VTI GES
Sbjct: 162 NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGES 221

Query: 221 AGAASVHLLMLSRASKGLFNKAIIMSGTAI 250
           AG  SV +L+LS  +K LF++AI  SG A+
Sbjct: 222 AGGESVSVLVLSPLAKNLFHRAISESGVAL 251


>BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.
          Length = 442

 Score =  130 bits (315), Expect = 1e-29
 Identities = 120/440 (27%), Positives = 196/440 (44%), Gaps = 46/440 (10%)

Query: 111 NVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYR 170
           NV+ PA A         D  LP++V   GG F  G+ +    G +L   + V++V   +R
Sbjct: 1   NVYAPARAP-------GDPQLPVMVWFPGGAFIVGAAS-SYEGSDLAAREKVVLVFLQHR 52

Query: 171 LAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLM 230
           L IFG+LS       GN GL D +  L+WVQ N   FGGDP  VT+ G+SAGA S+  LM
Sbjct: 53  LGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLM 112

Query: 231 LSRASKGLFNKAIIMSGTAIPN-FYSSSPI-YAKYISDMFLGELGLNSTELTSDEIHQTL 288
           +S  + GLF++AI  SGTA+   F + +P+  AK ++   L     NST++    +   L
Sbjct: 113 MSPLASGLFHRAISQSGTALFRLFITRNPLKVAKKVA--HLAGCNHNSTQI----LVNCL 166

Query: 289 TELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIID-----DDPITLINQGVGKDI 343
             L    +MR ++ +++     +F    E+     + ++D     DDP+ L+ QG    +
Sbjct: 167 RALSGTKVMRVSNKMRFLQ--LNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSV 224

Query: 344 PLLMGFNKDEGEYFKWII------TIYNIVDRYKSNPAVILSPRLAYELPPQEAS--AKG 395
           P L+G N  E   F W++       +     R ++   ++ S R    +  ++     + 
Sbjct: 225 PYLLGVNNLE---FNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEE 281

Query: 396 IFVGKRYFDGEPTVDGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITK 455
                   D +   +  +  V D  F Y  ++ A +       P Y YEF + +   I K
Sbjct: 282 YLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYH-RDAGLPVYLYEFEHHARGIIVK 340

Query: 456 RANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTC 515
                   G  H +++ ++F      G  +          M+ W     +N+ R  NP  
Sbjct: 341 PRT----DGADHGDEMYFLFGGPFATGLSMGKEKALSLQMMKYW-----ANFARTGNP-- 389

Query: 516 NKRDDPRWPPINEEELMFQV 535
           N  + P WP  N++E   Q+
Sbjct: 390 NDGNLPCWPRYNKDEKYLQL 409


>AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-related
           protein protein.
          Length = 288

 Score =  122 bits (293), Expect = 4e-27
 Identities = 78/211 (36%), Positives = 108/211 (51%), Gaps = 17/211 (8%)

Query: 49  FQGIPYAKPPVGARRFX----XXXXXXXXXXXFYA--YEEGPACPSRDITYGSITVKRK- 101
           F GIP+AKPP+G  RF                 Y   + + P    + I+      K   
Sbjct: 51  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATLYPPMFTQDPRRGGQLISELFTNRKENI 110

Query: 102 --GMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLML 159
              +SE+C+Y N++ PA       +L + N LP++V IHGGG   G+ +    G  L   
Sbjct: 111 PLKLSEDCLYLNIYTPA-------DLTKKNRLPVMVWIHGGGLMVGAAST-YDGLALAAH 162

Query: 160 KDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGE 219
           ++V+VV   YRL I+G+ S      PGN G  D +  L WVQ N   FGG+P  VTI G 
Sbjct: 163 ENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGG 222

Query: 220 SAGAASVHLLMLSRASKGLFNKAIIMSGTAI 250
           SAG  SV +L+LS  +K LF++AI  SG A+
Sbjct: 223 SAGGESVSVLVLSPLAKNLFHRAISESGVAL 253


>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
          Length = 2768

 Score =  117 bits (282), Expect = 1e-25
 Identities = 93/331 (28%), Positives = 159/331 (48%), Gaps = 29/331 (8%)

Query: 31   GPVCGREESANKNTKYFS---FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACP 87
            G + GR ++    T +     F G+PYA PP+  RRF            + A +   +C 
Sbjct: 2207 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGS-WDASKPRASCW 2265

Query: 88   SRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGG-GFQTGS 146
                  G+ T    G+SE+C+Y NVF+P +   N+          +LV  H     +   
Sbjct: 2266 QP----GTRTSTSPGVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESE 2312

Query: 147  GNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKV 206
            G   + G  L  + ++IVV  +YR+ +FG+LS  S ++ GN GL D V  L WVQ + + 
Sbjct: 2313 GWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRG 2372

Query: 207  FGGDPKRVTILGESAGA--ASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYI 264
            FGGDP+RV++  +  GA  AS+HLL     +  LF +A++M G+A+      S   A+  
Sbjct: 2373 FGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQ 2432

Query: 265  SDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAG-LTSFVPVVEKEGHDY 323
            +     E+    +  +S E+   L + P + +  A   +   +G    + PV+  +GH  
Sbjct: 2433 AIALAKEVSCPMS--SSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVI--DGH-- 2486

Query: 324  TRIIDDDPITLINQGVGKDIPLLMGFNKDEG 354
               + + P   + + +  ++ LL+G ++D+G
Sbjct: 2487 --FLREPPARALKRSLXVEVDLLIGSSQDDG 2515


>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
          Length = 1124

 Score =  117 bits (281), Expect = 1e-25
 Identities = 93/331 (28%), Positives = 159/331 (48%), Gaps = 29/331 (8%)

Query: 31  GPVCGREESANKNTKYFS---FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACP 87
           G + GR ++    T +     F G+PYA PP+  RRF            + A +   +C 
Sbjct: 563 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGS-WDASKPRASCW 621

Query: 88  SRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGG-GFQTGS 146
                 G+ T    G+SE+C+Y NVF+P +   N+          +LV  H     +   
Sbjct: 622 QP----GTRTSTSPGVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESE 668

Query: 147 GNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKV 206
           G   + G  L  + ++IVV  +YR+ +FG+LS  S ++ GN GL D V  L WVQ + + 
Sbjct: 669 GWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRG 728

Query: 207 FGGDPKRVTILGESAGA--ASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYI 264
           FGGDP+RV++  +  GA  AS+HLL     +  LF +A++M G+A+      S   A+  
Sbjct: 729 FGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQ 788

Query: 265 SDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAG-LTSFVPVVEKEGHDY 323
           +     E+    +  +S E+   L + P + +  A   +   +G    + PV+  +GH  
Sbjct: 789 AIALAKEVSCPMS--SSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVI--DGH-- 842

Query: 324 TRIIDDDPITLINQGVGKDIPLLMGFNKDEG 354
              + + P   + + +  ++ LL+G ++D+G
Sbjct: 843 --FLREPPARALKRSLWVEVDLLIGSSQDDG 871


>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
            variant protein.
          Length = 1574

 Score =  117 bits (281), Expect = 1e-25
 Identities = 93/331 (28%), Positives = 159/331 (48%), Gaps = 29/331 (8%)

Query: 31   GPVCGREESANKNTKYFS---FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACP 87
            G + GR ++    T +     F G+PYA PP+  RRF            + A +   +C 
Sbjct: 1013 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGS-WDASKPRASCW 1071

Query: 88   SRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGG-GFQTGS 146
                  G+ T    G+SE+C+Y NVF+P +   N+          +LV  H     +   
Sbjct: 1072 QP----GTRTSTSPGVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESE 1118

Query: 147  GNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKV 206
            G   + G  L  + ++IVV  +YR+ +FG+LS  S ++ GN GL D V  L WVQ + + 
Sbjct: 1119 GWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRG 1178

Query: 207  FGGDPKRVTILGESAGA--ASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYI 264
            FGGDP+RV++  +  GA  AS+HLL     +  LF +A++M G+A+      S   A+  
Sbjct: 1179 FGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQ 1238

Query: 265  SDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAG-LTSFVPVVEKEGHDY 323
            +     E+    +  +S E+   L + P + +  A   +   +G    + PV+  +GH  
Sbjct: 1239 AIALAKEVSCPMS--SSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVI--DGH-- 1292

Query: 324  TRIIDDDPITLINQGVGKDIPLLMGFNKDEG 354
               + + P   + + +  ++ LL+G ++D+G
Sbjct: 1293 --FLREPPARALKRSLWVEVDLLIGSSQDDG 1321


>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
          Length = 2767

 Score =  115 bits (276), Expect = 5e-25
 Identities = 92/331 (27%), Positives = 158/331 (47%), Gaps = 29/331 (8%)

Query: 31   GPVCGREESANKNTKYFS---FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACP 87
            G + GR ++    T +     F G+PYA PP+  R F            + A +   +C 
Sbjct: 2206 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERHFQAPEPLNWTGS-WDASKPRASCW 2264

Query: 88   SRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGG-GFQTGS 146
                  G+ T    G+SE+C+Y NVF+P +   N+          +LV  H     +   
Sbjct: 2265 QP----GTRTSTSPGVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESE 2311

Query: 147  GNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKV 206
            G   + G  L  + ++IVV  +YR+ +FG+LS  S ++ GN GL D V  L WVQ + + 
Sbjct: 2312 GWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRG 2371

Query: 207  FGGDPKRVTILGESAGA--ASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYI 264
            FGGDP+RV++  +  GA  AS+HLL     +  LF +A++M G+A+      S   A+  
Sbjct: 2372 FGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQ 2431

Query: 265  SDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAG-LTSFVPVVEKEGHDY 323
            +     E+    +  +S E+   L + P + +  A   +   +G    + PV+  +GH  
Sbjct: 2432 AIALAKEVSCPMS--SSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVI--DGH-- 2485

Query: 324  TRIIDDDPITLINQGVGKDIPLLMGFNKDEG 354
               + + P   + + +  ++ LL+G ++D+G
Sbjct: 2486 --FLREPPARALKRSLWVEVDLLIGSSQDDG 2514


>BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for
           IMAGE:40133565) protein.
          Length = 422

 Score =  113 bits (273), Expect = 1e-24
 Identities = 74/226 (32%), Positives = 115/226 (50%), Gaps = 20/226 (8%)

Query: 31  GPVCGREESANKNTKYFS---FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPACP 87
           G + GR ++    T +     F G+PYA PP+  RRF            + A +   +C 
Sbjct: 169 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGS-WDASKPRASCW 227

Query: 88  SRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGG-GFQTGS 146
                 G+ T    G+SE+C+Y NVF+P +   N+          +LV  H     +   
Sbjct: 228 QP----GTRTSTSPGVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESE 274

Query: 147 GNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKV 206
           G   + G  L  + ++IVV  +YR+ +FG+LS  S ++ GN GL D V  L WVQ + + 
Sbjct: 275 GWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRG 334

Query: 207 FGGDPKRVTILGESAGA--ASVHLLMLSRASKGLFNKAIIMSGTAI 250
           FGGDP+RV++  +  GA  AS+HLL     +  LF +A++M G+A+
Sbjct: 335 FGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 380


>BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.
          Length = 151

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 52/117 (44%), Positives = 68/117 (58%), Gaps = 1/117 (0%)

Query: 134 LVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDM 193
           +V IHGGG   G+ +    G  L   ++V+VV   YRL I+G+ S      PGN G  D 
Sbjct: 1   MVWIHGGGLMVGAAST-YDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQ 59

Query: 194 VTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAI 250
           +  L WVQ N   FGG+P  VTI G SAG  SV +L+LS  +K LF++AI  SG A+
Sbjct: 60  LAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVAL 116


>AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40219 fis, clone TESTI2021637, moderately
           similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
           3.1.1.1). ).
          Length = 207

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 51/126 (40%), Positives = 66/126 (52%), Gaps = 2/126 (1%)

Query: 134 LVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDM 193
           +V +HGG   TG+      G  L    DV+VV   YRL + G+ S      PGN G  D+
Sbjct: 1   MVWVHGGALITGAAT-SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDV 59

Query: 194 VTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGT-AIPN 252
           V  L+WVQ N   FGGD   VT+ G SAG + +  L+LS  + GLF++AI  SG    P 
Sbjct: 60  VAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPG 119

Query: 253 FYSSSP 258
              S P
Sbjct: 120 IIDSHP 125


>AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
           LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
          Length = 367

 Score = 93.5 bits (222), Expect = 2e-18
 Identities = 92/354 (25%), Positives = 156/354 (44%), Gaps = 38/354 (10%)

Query: 197 LKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAI-PNFYS 255
           L+WVQ N   FGGDP  VT+ G+SAGA S+  LM+S  + GLF++AI  SGTA+   F +
Sbjct: 4   LRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRPFIT 63

Query: 256 SSPI-YAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVP 314
           S+P+  AK ++   L     NST++    +   L  L    +MR ++ +++     +F  
Sbjct: 64  SNPLKVAKKVA--HLAGCNHNSTQI----LVNCLRALSGTKVMRVSNKMRFLQ--LNFQR 115

Query: 315 VVEKEGHDYTRIID-----DDPITLINQGVGKDIPLLMGFNKDEGEYFKWII------TI 363
             E+     + ++D     DDP+ L+ QG    +P L+G N  E   F W++       +
Sbjct: 116 DPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLE---FNWLLPYIMKFPL 172

Query: 364 YNIVDRYKSNPAVILSPRLAYELPPQEAS--AKGIFVGKRYFDGEPTVDGFVKSVTDIYF 421
                R ++   ++ S R    +  ++     +         D +   +  +  V D  F
Sbjct: 173 NRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATF 232

Query: 422 QYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFL 481
            Y  ++ A +       P Y YEF + +   I K        G  H +++ ++F      
Sbjct: 233 VYATLQTAHYH-RDAGLPVYLYEFEHHARGIIVKPRT----DGADHGDEMYFLFGGPFAT 287

Query: 482 GSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRDDPRWPPINEEELMFQV 535
           G  +          M+ W     +N+ R  NP  N  + P WP  N++E   Q+
Sbjct: 288 GLSMGKEKALSLQMMKYW-----ANFARTGNP--NDGNLPCWPRYNKDEKYLQL 334


>BC032567-1|AAH32567.1|  134|Homo sapiens NLGN4Y protein protein.
          Length = 134

 Score = 48.8 bits (111), Expect = 5e-05
 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 17/88 (19%)

Query: 104 SENCIYANVFVP----ASATLNSDELC-----------EDNSL-PILVNIHGGGFQTGSG 147
           +E+C+Y N++VP     +   N+D++            E NS  P++V IHGG +  G+G
Sbjct: 21  NEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIHEQNSKKPVMVYIHGGSYMEGTG 80

Query: 148 NRDLHGPELLMLKDVIVVNFNYRLAIFG 175
           N  + G  L    +VIV+  NYRL I G
Sbjct: 81  NM-IDGSILASYGNVIVITINYRLGILG 107


>BC009706-1|AAH09706.1|  150|Homo sapiens CES1 protein protein.
          Length = 150

 Score = 38.7 bits (86), Expect = 0.054
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 8/79 (10%)

Query: 49  FQGIPYAKPPVGARRFXXXXXXXXXXXXFYAYEEGPAC---PSRDITYGSITVKRK---- 101
           F GIP+AKPP+G  RF              A    P C   P        +   RK    
Sbjct: 51  FLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIP 110

Query: 102 -GMSENCIYANVFVPASAT 119
             +SE+C+Y N++ PA  T
Sbjct: 111 LKLSEDCLYLNIYTPADLT 129


>L32179-1|AAA35551.1|  399|Homo sapiens arylacetamide deacetylase
           protein.
          Length = 399

 Score = 35.9 bits (79), Expect = 0.38
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 18/96 (18%)

Query: 134 LVNIHGGGFQTGSGNRDLHGPELLML-----KDVIVVNFNYRLAIFGYLSLASHKIPGNN 188
           L  IHGGG+  GS    L G +LL        D +VV+ NYRLA         +  P   
Sbjct: 107 LFYIHGGGWCVGSAA--LSGYDLLSRWTADRLDAVVVSTNYRLA-------PKYHFPIQ- 156

Query: 189 GLRDMVTLLKWVQRNAKV--FGGDPKRVTILGESAG 222
              D+   L+W  R   +  +G +P+R+ I G+SAG
Sbjct: 157 -FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAG 191


>BC032309-1|AAH32309.1|  399|Homo sapiens arylacetamide deacetylase
           (esterase) protein.
          Length = 399

 Score = 35.9 bits (79), Expect = 0.38
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 18/96 (18%)

Query: 134 LVNIHGGGFQTGSGNRDLHGPELLML-----KDVIVVNFNYRLAIFGYLSLASHKIPGNN 188
           L  IHGGG+  GS    L G +LL        D +VV+ NYRLA         +  P   
Sbjct: 107 LFYIHGGGWCVGSAA--LSGYDLLSRWTADRLDAVVVSTNYRLA-------PKYHFPIQ- 156

Query: 189 GLRDMVTLLKWVQRNAKV--FGGDPKRVTILGESAG 222
              D+   L+W  R   +  +G +P+R+ I G+SAG
Sbjct: 157 -FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAG 191


>AL513016-5|CAH74176.2|  350|Homo sapiens arylacetamide
           deacetylase-like 3 protein.
          Length = 350

 Score = 35.1 bits (77), Expect = 0.67
 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 8/93 (8%)

Query: 132 PILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLR 191
           P +V  HGGG   GS  +  HG    + K+    + +  LA+ GY  L  HK P    +R
Sbjct: 56  PGIVYYHGGGGVMGS-LKTHHGICSRLCKE----SDSVVLAV-GYRKLPKHKFPVP--VR 107

Query: 192 DMVTLLKWVQRNAKVFGGDPKRVTILGESAGAA 224
           D +       ++   +G DP RV + G+S G A
Sbjct: 108 DCLVATIHFLKSLDAYGVDPARVVVCGDSFGGA 140


>BC069238-1|AAH69238.1|  403|Homo sapiens zinc finger, CCHC domain
           containing 3 protein.
          Length = 403

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 81  EEGPACPSRDITYGSITVKRKGMSENCIYANVFVPAS 117
           +EG ACP+RD   G++ ++  GM  + IYA + +P S
Sbjct: 174 DEG-ACPTRDFVVGALILRSIGMDPSDIYAVIQIPGS 209


>AL034548-4|CAB81631.1|  404|Homo sapiens zinc finger, CCHC domain
           containing 3 protein.
          Length = 404

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 81  EEGPACPSRDITYGSITVKRKGMSENCIYANVFVPAS 117
           +EG ACP+RD   G++ ++  GM  + IYA + +P S
Sbjct: 175 DEG-ACPTRDFVVGALILRSIGMDPSDIYAVIQIPGS 210


>BC065724-1|AAH65724.1|  379|Homo sapiens arylacetamide
           deacetylase-like 2 protein.
          Length = 379

 Score = 32.7 bits (71), Expect = 3.6
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 14/94 (14%)

Query: 134 LVNIHGGGFQTGSGNR---DLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGL 190
           ++  HGGGF  GS  +   D          D +VV  +YRLA         H  P     
Sbjct: 85  VIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLA-------PQHHFPAQ--F 135

Query: 191 RDMVTLLKW--VQRNAKVFGGDPKRVTILGESAG 222
            D +  +K+  +++    +G DP R+ I G+S+G
Sbjct: 136 EDGLAAVKFFLLEKILTKYGVDPTRICISGDSSG 169


>AL513016-2|CAH74173.1|  407|Homo sapiens arylacetamide
           deacetylase-like 4 protein.
          Length = 407

 Score = 32.3 bits (70), Expect = 4.7
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 171 LAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASV 226
           L + GY  L  H  P     +D +       +  + +G DP RV + GES G A+V
Sbjct: 146 LLMIGYRKLPDHHSPAL--FQDCMNASIHFLKALETYGVDPSRVVVCGESVGGAAV 199


>AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.
          Length = 550

 Score = 32.3 bits (70), Expect = 4.7
 Identities = 35/118 (29%), Positives = 60/118 (50%), Gaps = 14/118 (11%)

Query: 241 KAIIMSGTAIPNF-YSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRA 299
           KAI  SGTAI ++  +  P+  KY + +   ++G +  +  S E  + L   P  +++  
Sbjct: 1   KAIAQSGTAISSWSVNYQPL--KY-TRLLAAKVGCDRED--SAEAVECLRRKPSRELVD- 54

Query: 300 NDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYF 357
            DV   R  + +F PVV+ +      ++ DDP  L+ QG   +  +L+G N+ EG  F
Sbjct: 55  QDVQPARYHI-AFGPVVDGD------VVPDDPEILMQQGEFLNYDMLIGVNQGEGLKF 105


>AL513016-4|CAH74175.1|  280|Homo sapiens arylacetamide
           deacetylase-like 3 protein.
          Length = 280

 Score = 31.5 bits (68), Expect = 8.2
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 2/50 (4%)

Query: 175 GYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAA 224
           GY  L  HK P    +RD +       ++   +G DP RV + G+S G A
Sbjct: 23  GYRKLPKHKFPVP--VRDCLVATIHFLKSLDAYGVDPARVVVCGDSFGGA 70


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.138    0.415 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,884,053
Number of Sequences: 224733
Number of extensions: 3716818
Number of successful extensions: 7352
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 6907
Number of HSP's gapped (non-prelim): 207
length of query: 566
length of database: 73,234,838
effective HSP length: 94
effective length of query: 472
effective length of database: 52,109,936
effective search space: 24595889792
effective search space used: 24595889792
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)

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