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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000773-TA|BGIBMGA000773-PA|IPR002018|Carboxylesterase,
type B
         (503 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens ...   146   1e-34
BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.        145   3e-34
BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.        145   3e-34
AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5 prot...   145   3e-34
BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked ...   132   2e-30
AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.        132   2e-30
AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.    132   2e-30
BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked ...   130   1e-29
BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked ...   130   1e-29
AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.        130   1e-29
AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.    127   1e-28
AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.               123   1e-27
BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.    120   2e-26
BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7 prot...   118   5e-26
BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.        118   5e-26
AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens ...   118   5e-26
Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.      117   1e-25
U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.      117   1e-25
M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase pro...   117   1e-25
M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.                  117   1e-25
M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.                  117   1e-25
D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precurso...   117   1e-25
BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2 (int...   117   1e-25
BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase p...   117   1e-25
AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2 (int...   117   1e-25
AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isof...   116   1e-25
AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo pr...   116   3e-25
AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.        114   6e-25
BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.        113   1e-24
AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform pr...   113   1e-24
AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform pr...   113   1e-24
AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.    113   1e-24
AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HN...   113   2e-24
AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase ...   109   2e-23
BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.       109   2e-23
S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipas...   107   7e-23
X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for ...   106   2e-22
M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase pro...   106   2e-22
M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase prot...   106   2e-22
M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipas...   106   2e-22
AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase (...   106   2e-22
AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lip...   106   2e-22
AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase p...   106   2e-22
BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.         104   6e-22
AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase ...   104   6e-22
BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.        104   8e-22
BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.        104   8e-22
X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage serin...   103   1e-21
BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1 (mon...   103   1e-21
S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholester...   103   2e-21
M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.      103   2e-21
M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.      103   2e-21
D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.      103   2e-21
BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1 (mon...   103   2e-21
AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester hydro...   103   2e-21
AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.              103   2e-21
AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b p...   103   2e-21
AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a p...   103   2e-21
AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b p...   103   2e-21
AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a p...   103   2e-21
L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.      102   3e-21
AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HN...   102   3e-21
L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.      101   4e-21
BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.    101   8e-21
BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.        101   8e-21
AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo pr...   101   8e-21
AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.    101   8e-21
M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.      100   1e-20
M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase prot...    96   2e-19
BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase, i...    96   2e-19
BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Y...    96   2e-19
BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.         96   2e-19
AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (Y...    96   2e-19
AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase is...    96   2e-19
AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related acety...    96   2e-19
AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.              96   2e-19
AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.              96   2e-19
BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein pr...    95   4e-19
BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.         95   4e-19
AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-relate...    92   4e-18
AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens ...    91   6e-18
AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase ...    90   1e-17
AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens ...    88   8e-17
BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.         84   1e-15
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.          69   3e-11
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.          69   3e-11
BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for IM...    69   3e-11
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.        69   3e-11
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor...    69   3e-11
AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.     55   5e-07
AK074522-1|BAC11039.1|  509|Homo sapiens protein ( Homo sapiens ...    39   0.047
AY533507-1|AAS45401.1|  796|Homo sapiens ARC/mediator transcript...    35   0.77 

>AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 469

 Score =  146 bits (355), Expect = 1e-34
 Identities = 118/422 (27%), Positives = 194/422 (45%), Gaps = 43/422 (10%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 12  SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 71

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 72  GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 131

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 132 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 191

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG NS E    
Sbjct: 192 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNSHECGFL 243

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 244 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 299

Query: 360 YHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS 419
              DV+F+     +A YH    + VYFY F H  +     +P   K  A H+DE+ ++F 
Sbjct: 300 LLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVK--ADHADEVRFVFG 357

Query: 420 GRNL----------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRL-LDI 468
           G  L           +E+ L+   ++++W  F    NP       W   N     L LD+
Sbjct: 358 GAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDL 417

Query: 469 GV 470
            +
Sbjct: 418 NM 419


>BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  145 bits (352), Expect = 3e-34
 Identities = 117/422 (27%), Positives = 194/422 (45%), Gaps = 43/422 (10%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG N+ E    
Sbjct: 298 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 350 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 405

Query: 360 YHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS 419
              DV+F+     +A YH    + VYFY F H  +     +P   K  A H+DE+ ++F 
Sbjct: 406 LLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVK--ADHADEVRFVFG 463

Query: 420 GRNL----------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRL-LDI 468
           G  L           +E+ L+   ++++W  F    NP       W   N     L LD+
Sbjct: 464 GAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDL 523

Query: 469 GV 470
            +
Sbjct: 524 NM 525


>BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  145 bits (352), Expect = 3e-34
 Identities = 117/422 (27%), Positives = 194/422 (45%), Gaps = 43/422 (10%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG N+ E    
Sbjct: 298 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 350 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 405

Query: 360 YHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS 419
              DV+F+     +A YH    + VYFY F H  +     +P   K  A H+DE+ ++F 
Sbjct: 406 LLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVK--ADHADEVRFVFG 463

Query: 420 GRNL----------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRL-LDI 468
           G  L           +E+ L+   ++++W  F    NP       W   N     L LD+
Sbjct: 464 GAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDL 523

Query: 469 GV 470
            +
Sbjct: 524 NM 525


>AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5
           protein.
          Length = 575

 Score =  145 bits (352), Expect = 3e-34
 Identities = 117/422 (27%), Positives = 194/422 (45%), Gaps = 43/422 (10%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG N+ E    
Sbjct: 298 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 350 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 405

Query: 360 YHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS 419
              DV+F+     +A YH    + VYFY F H  +     +P   K  A H+DE+ ++F 
Sbjct: 406 LLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVK--ADHADEVRFVFG 463

Query: 420 GRNL----------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRL-LDI 468
           G  L           +E+ L+   ++++W  F    NP       W   N     L LD+
Sbjct: 464 GAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDL 523

Query: 469 GV 470
            +
Sbjct: 524 NM 525


>BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked
           protein.
          Length = 816

 Score =  132 bits (320), Expect = 2e-30
 Identities = 118/459 (25%), Positives = 205/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VPT           PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 144 EDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 203

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 204 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 263

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 264 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNY 323

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 384 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 441

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 442 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 494

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 495 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 554

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 555 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593


>AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.
          Length = 816

 Score =  132 bits (320), Expect = 2e-30
 Identities = 118/459 (25%), Positives = 205/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VPT           PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 144 EDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 203

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 204 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 263

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 264 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNY 323

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 384 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 441

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 442 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 494

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 495 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 554

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 555 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593


>AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.
          Length = 817

 Score =  132 bits (320), Expect = 2e-30
 Identities = 118/459 (25%), Positives = 205/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VPT           PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 145 EDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 204

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 205 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 264

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 265 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNY 324

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 325 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 384

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 385 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 442

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 443 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 495

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 496 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 555

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 556 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 594


>BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  130 bits (314), Expect = 1e-29
 Identities = 117/459 (25%), Positives = 204/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VP            PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 144 EDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 203

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 204 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 263

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 264 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 384 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 441

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 442 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 494

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 495 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 554

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 555 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593


>BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  130 bits (314), Expect = 1e-29
 Identities = 117/459 (25%), Positives = 204/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VP            PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 144 EDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 203

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 204 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 263

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 264 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 384 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 441

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 442 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 494

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 495 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 554

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 555 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593


>AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.
          Length = 816

 Score =  130 bits (314), Expect = 1e-29
 Identities = 117/459 (25%), Positives = 204/459 (44%), Gaps = 57/459 (12%)

Query: 79  EECLQLDVNVPTS-----AAPTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRH 126
           E+CL L++ VP            PV+V++ G       G+   G ++     VIV+ + +
Sbjct: 144 EDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINY 203

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GFL   ++   GN G  D I AL W+ +N+ AF G+P RV + G G GA+ V  L
Sbjct: 204 RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL 263

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATM 241
           TL+  +EGLF   I+QSG+ L+ WA NY      +++ +++        D V+   N   
Sbjct: 264 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323

Query: 242 EELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGY 295
           +EL  ++    T + +FG  ++ + + ++ +  +E      YD+ +   + + +  + G 
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383

Query: 296 NSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT 355
             +E  +  +   +F V N +     +    +      + M       E+   RR +T+ 
Sbjct: 384 VDNEDGVTPNDF-DFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLV 441

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   +++    +A  HA   S  YFY F H      Q E     + +AH DE+ 
Sbjct: 442 ALFTDHQ---WVAPAVATADLHAQYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVP 494

Query: 416 YLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHR 450
           Y+F             N  K D ++  +++ +W NF                IH  P   
Sbjct: 495 YVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF 554

Query: 451 QPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
           + + W   N ++   L IG++P++ D+       FW E+
Sbjct: 555 EEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593


>AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.
          Length = 679

 Score =  127 bits (306), Expect = 1e-28
 Identities = 111/436 (25%), Positives = 195/436 (44%), Gaps = 52/436 (11%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +RLG  GFL   ++   GN G  D
Sbjct: 30  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 89

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL W+ +N+ AF G+P RV + G G GA+ V  LTL+  +EGLF   I+QSG+ L+ 
Sbjct: 90  QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 149

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY      +++ +++        D V+   N   +EL  ++    T + +FG  ++ 
Sbjct: 150 WAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDG 209

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++ +  +E      YD+ +   + + +  + G   +E  +  +   +F V N +  
Sbjct: 210 DVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF-DFSVSNFVDN 268

Query: 319 DISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYHA 378
              +    +      + M       E+   RR +T+ AL   H+   +++    +A  HA
Sbjct: 269 LYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLVALFTDHQ---WVAPAVATADLHA 324

Query: 379 AVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKEDG 428
              S  YFY F H      Q E     + +AH DE+ Y+F             N  K D 
Sbjct: 325 QYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDV 380

Query: 429 LVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEPK 473
           ++  +++ +W NF                IH  P   + + W   N ++   L IG++P+
Sbjct: 381 MLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPR 440

Query: 474 MIDYPYEKTSKFWEEI 489
           + D+       FW E+
Sbjct: 441 VRDHYRATKVAFWLEL 456


>AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.
          Length = 816

 Score =  123 bits (297), Expect = 1e-27
 Identities = 112/436 (25%), Positives = 194/436 (44%), Gaps = 53/436 (12%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +RLG  GFL   ++   GN G  D
Sbjct: 168 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 227

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL W+ +N+ AF G+P RV + G G GA+ V  LTL+  +EGLF   I+QSG+ L+ 
Sbjct: 228 QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 287

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY      +++ +++        D V+   N   +EL  ++    T + +FG  ++ 
Sbjct: 288 WAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDG 347

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++ +  +E      YD+ +   + + +  + G   +E  +  +   +F V N +  
Sbjct: 348 DVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDF-DFSVSNFVDN 406

Query: 319 DISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYHA 378
              +    +      + M       E+   RR +T+ AL   H+  +    V  +A  HA
Sbjct: 407 LYGYPEGKDTLRETIKFMYTDWADKENPETRR-KTLVALFTDHQ--WVAPAV--AADLHA 461

Query: 379 AVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKEDG 428
              S  YFY F H      Q E     + +AH DE+ Y+F             N  K D 
Sbjct: 462 QYGSPTYFYAFYH----HCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDV 517

Query: 429 LVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEPK 473
           ++  +++ +W NF                IH  P   + + W   N ++   L IG++P+
Sbjct: 518 MLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPR 577

Query: 474 MIDYPYEKTSKFWEEI 489
           + D+       FW E+
Sbjct: 578 VRDHYRATKVAFWLEL 593


>BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.
          Length = 442

 Score =  120 bits (288), Expect = 2e-26
 Identities = 110/434 (25%), Positives = 186/434 (42%), Gaps = 33/434 (7%)

Query: 94  PTWPVLVW------VTGSDGSYHSGQLV-KKGVIVVIVRHRLGAPGFLCYERD-IPGNAG 145
           P  PV+VW      + G+  SY    L  ++ V++V ++HRLG  GFL  +     GN G
Sbjct: 12  PQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWG 71

Query: 146 AKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSI 205
             D +AAL WV++NI AF G+P  V + GQ  GA  +  L ++P+A GLFH  I QSG+ 
Sbjct: 72  LLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTA 131

Query: 206 LAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNA----TMEELFIKSSESNTPYFSFGLC 261
           L       +    AK +        +   + +N     +  ++   S++      +F   
Sbjct: 132 LFRLFITRNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRD 191

Query: 262 LEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINK- 315
            EE + +     +     + P  L    K  SVP ++G N+ E       + +F +  + 
Sbjct: 192 PEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQA 251

Query: 316 LTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNR-----TMTALLAYHRDVYFLSHV 370
           + K+    + +  + L +    QV   +E+     N          ++   +D  F+   
Sbjct: 252 MRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYAT 311

Query: 371 YRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDK 425
            ++A YH      VY Y F H    G+  +P  +  GA H DE+ +LF     +G ++ K
Sbjct: 312 LQTAHYHRDAGLPVYLYEFEHHAR-GIIVKP--RTDGADHGDEMYFLFGGPFATGLSMGK 368

Query: 426 EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKF 485
           E  L   ++ ++W NF    NP       W P   ++ + L +    ++     EK   F
Sbjct: 369 EKALSLQMM-KYWANFARTGNPNDGNLPCW-PRYNKDEKYLQLDFTTRVGMKLKEKKMAF 426

Query: 486 WEEIYDKYYYSRNR 499
           W  +Y      + R
Sbjct: 427 WMSLYQSQRPEKQR 440


>BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7
           protein.
          Length = 525

 Score =  118 bits (284), Expect = 5e-26
 Identities = 91/318 (28%), Positives = 152/318 (47%), Gaps = 30/318 (9%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG N+ E    
Sbjct: 298 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 350 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 405

Query: 360 YHRDVYFLSHVYRSASYH 377
              DV+F+     +A YH
Sbjct: 406 LLGDVFFVVPALITARYH 423


>BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.
          Length = 568

 Score =  118 bits (284), Expect = 5e-26
 Identities = 124/443 (27%), Positives = 188/443 (42%), Gaps = 45/443 (10%)

Query: 76  SAAEECLQLDVNVPTS--AAPTWPVLVWV------TGSDGSYHSGQLVKKG-VIVVIVRH 126
           S +E+CL L+V  P    A    PV+VWV      TG+  SY    L   G V+VV V++
Sbjct: 119 SVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQY 178

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    +   PGN G  DV+AAL WV++NI  F G+   V V G   G +++  L
Sbjct: 179 RLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERL----DKKRDYVDVFLNATM 241
            L+P+A GLFH  I QSG I  P   +      A+ I   L        + V        
Sbjct: 239 VLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEG 298

Query: 242 EELFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAY 301
           EEL +     NT Y         PL  +   F ++P +L   K   SVP ++G N+ E  
Sbjct: 299 EELVLSKKLKNTIY---------PLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHE-- 347

Query: 302 IFSSLL-KEFKVINKLTK-DISFLLPYELQFLNSREM-NQVSRQIEDIYFRRN----RTM 354
            FS L+ + + +++ + +     +L      L S ++  ++   + D Y   N       
Sbjct: 348 -FSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKC 406

Query: 355 TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDEL 414
            A   +  DV+        + Y     S V+FY F H      + +P   K  A H  E 
Sbjct: 407 QAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK--ADHGAEG 464

Query: 415 AYLFSGRNL---------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRL 465
           A++F G  L          +E+  +   ++  W +F    +P  +    W   N +  + 
Sbjct: 465 AFVFGGPFLMDESSRLEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFN-QAEQY 523

Query: 466 LDIGVEPKMIDYPYEKTSKFWEE 488
           L+I   P+      E   +FW E
Sbjct: 524 LEINPVPRAGQKFREAWMQFWSE 546


>AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 525

 Score =  118 bits (284), Expect = 5e-26
 Identities = 91/318 (28%), Positives = 152/318 (47%), Gaps = 30/318 (9%)

Query: 78  AEECLQLDVNVPTSA--APTWPVLVWV------TGSDGSYHSGQLVK-KGVIVVIVRHRL 128
           +E+CL L++  P  A      PVLVW       TGS   +    L   + V+VV+V++RL
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177

Query: 129 GAPGFLC-YERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF   +++  PGN   KD +AAL WV+ NI  F G+P+ V + G+  GA  V +L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237

Query: 188 TPMAEGLFHGVILQSGSILAPW--AFNYDAKDRAKVIGERLDKKRDYVDVFLNA--TMEE 243
           +PMA+GLFH  I++SG  + P+  A +Y+  +  +V+           +  L    T   
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297

Query: 244 LFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIF 303
             + +    T  F+  +        +  FF   P DL   K  K++P IIG N+ E    
Sbjct: 298 KELLTLSQKTKSFTRVV--------DGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349

Query: 304 SSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMT----ALLA 359
             + +  ++++   K ++  L   +  +  + ++ V+ +    YF    ++T    +LL 
Sbjct: 350 LPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANE----YFHDKHSLTEIRDSLLD 405

Query: 360 YHRDVYFLSHVYRSASYH 377
              DV+F+     +A YH
Sbjct: 406 LLGDVFFVVPALITARYH 423


>Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.
          Length = 559

 Score =  117 bits (281), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 118 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 177

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 178 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 237

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 238 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 293

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 294 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 346

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 347 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 405

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 406 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 462

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 463 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 521

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 522 LQPAVGRALKAHRLQFWKK 540


>U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.
          Length = 550

 Score =  117 bits (281), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 109 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 168

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 169 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 228

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 229 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 284

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 285 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 337

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 338 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 396

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 397 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 453

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 454 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 512

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 513 LQPAVGRALKAHRLQFWKK 531


>M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  117 bits (281), Expect = 1e-25
 Identities = 141/546 (25%), Positives = 220/546 (40%), Gaps = 67/546 (12%)

Query: 6   LVMLFLIPGTEQNVI-SIAQGKIRGR---VRDGYVT-YGGIPYGSLML-KGRFKQAGIAP 59
           L ML     TE ++I +   GK+RG    V  G VT + GIPY    L + RFK+     
Sbjct: 19  LCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLT 78

Query: 60  VWPNIRE------------------FHESRC--STTSAAEECLQLDVNVPTSAAPTWPVL 99
            W +I                    FH S      T  +E+CL L+V +P        VL
Sbjct: 79  KWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVL 138

Query: 100 VWVTGSD-----GSYH--SGQLVKK--GVIVVIVRHRLGAPGFLCY--ERDIPGNAGAKD 148
           +W+ G        S H   G+ + +   VIVV + +R+GA GFL      + PGN G  D
Sbjct: 139 IWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFD 198

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
              AL WV+ NI AF GNP  V + G+  GAA V    L+P +  LF   ILQSGS  AP
Sbjct: 199 QQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAP 258

Query: 209 WAFN--YDAKDR----AKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCL 262
           WA    Y+A++R    AK+ G   + + + +    N   +E+ +  +E+    +   L +
Sbjct: 259 WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILL--NEAFVVPYGTPLSV 316

Query: 263 EEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDE--AYI------FSSLLKEFKVIN 314
                 +  F  + P  L    + K   +++G N DE  A++      FS          
Sbjct: 317 NFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRK 376

Query: 315 KLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSA 374
           +  + +    P   +F     +   +  ++D   R      AL     D  F+       
Sbjct: 377 EFQEGLKIFFPGVSEFGKESILFHYTDWVDD--QRPENYREALGDVVGDYNFICPALEFT 434

Query: 375 SYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS-----GRNLDKEDGL 429
              +   +  +FY F H       K P  +  G  H  E+ ++F        N  K + +
Sbjct: 435 KKFSEWGNNAFFYYFEHRS----SKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEI 490

Query: 430 VQDLLVRFWVNFVIHLNP--THRQPLDWDPMNYENPRLLDIGVE-PKMIDYPYEKTSKFW 486
           +   +V+ W NF  + NP  T      W        + L +  E  +++     +  +FW
Sbjct: 491 LSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFW 550

Query: 487 EEIYDK 492
              + K
Sbjct: 551 TSFFPK 556


>M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  117 bits (281), Expect = 1e-25
 Identities = 141/546 (25%), Positives = 220/546 (40%), Gaps = 67/546 (12%)

Query: 6   LVMLFLIPGTEQNVI-SIAQGKIRGR---VRDGYVT-YGGIPYGSLML-KGRFKQAGIAP 59
           L ML     TE ++I +   GK+RG    V  G VT + GIPY    L + RFK+     
Sbjct: 19  LCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLT 78

Query: 60  VWPNIRE------------------FHESRC--STTSAAEECLQLDVNVPTSAAPTWPVL 99
            W +I                    FH S      T  +E+CL L+V +P        VL
Sbjct: 79  KWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVL 138

Query: 100 VWVTGSD-----GSYH--SGQLVKK--GVIVVIVRHRLGAPGFLCY--ERDIPGNAGAKD 148
           +W+ G        S H   G+ + +   VIVV + +R+GA GFL      + PGN G  D
Sbjct: 139 IWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFD 198

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
              AL WV+ NI AF GNP  V + G+  GAA V    L+P +  LF   ILQSGS  AP
Sbjct: 199 QQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAP 258

Query: 209 WAFN--YDAKDR----AKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCL 262
           WA    Y+A++R    AK+ G   + + + +    N   +E+ +  +E+    +   L +
Sbjct: 259 WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILL--NEAFVVPYGTPLSV 316

Query: 263 EEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDE--AYI------FSSLLKEFKVIN 314
                 +  F  + P  L    + K   +++G N DE  A++      FS          
Sbjct: 317 NFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRK 376

Query: 315 KLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSA 374
           +  + +    P   +F     +   +  ++D   R      AL     D  F+       
Sbjct: 377 EFQEGLKIFFPGVSEFGKESILFHYTDWVDD--QRPENYREALGDVVGDYNFICPALEFT 434

Query: 375 SYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS-----GRNLDKEDGL 429
              +   +  +FY F H       K P  +  G  H  E+ ++F        N  K + +
Sbjct: 435 KKFSEWGNNAFFYYFEHRS----SKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEI 490

Query: 430 VQDLLVRFWVNFVIHLNP--THRQPLDWDPMNYENPRLLDIGVE-PKMIDYPYEKTSKFW 486
           +   +V+ W NF  + NP  T      W        + L +  E  +++     +  +FW
Sbjct: 491 LSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFW 550

Query: 487 EEIYDK 492
              + K
Sbjct: 551 TSFFPK 556


>M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  117 bits (281), Expect = 1e-25
 Identities = 141/546 (25%), Positives = 220/546 (40%), Gaps = 67/546 (12%)

Query: 6   LVMLFLIPGTEQNVI-SIAQGKIRGR---VRDGYVT-YGGIPYGSLML-KGRFKQAGIAP 59
           L ML     TE ++I +   GK+RG    V  G VT + GIPY    L + RFK+     
Sbjct: 19  LCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLT 78

Query: 60  VWPNIRE------------------FHESRC--STTSAAEECLQLDVNVPTSAAPTWPVL 99
            W +I                    FH S      T  +E+CL L+V +P        VL
Sbjct: 79  KWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVL 138

Query: 100 VWVTGSD-----GSYH--SGQLVKK--GVIVVIVRHRLGAPGFLCY--ERDIPGNAGAKD 148
           +W+ G        S H   G+ + +   VIVV + +R+GA GFL      + PGN G  D
Sbjct: 139 IWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFD 198

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
              AL WV+ NI AF GNP  V + G+  GAA V    L+P +  LF   ILQSGS  AP
Sbjct: 199 QQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAP 258

Query: 209 WAFN--YDAKDR----AKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCL 262
           WA    Y+A++R    AK+ G   + + + +    N   +E+ +  +E+    +   L +
Sbjct: 259 WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILL--NEAFVVPYGTPLSV 316

Query: 263 EEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDE--AYI------FSSLLKEFKVIN 314
                 +  F  + P  L    + K   +++G N DE  A++      FS          
Sbjct: 317 NFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRK 376

Query: 315 KLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSA 374
           +  + +    P   +F     +   +  ++D   R      AL     D  F+       
Sbjct: 377 EFQEGLKIFFPGVSEFGKESILFHYTDWVDD--QRPENYREALGDVVGDYNFICPALEFT 434

Query: 375 SYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS-----GRNLDKEDGL 429
              +   +  +FY F H       K P  +  G  H  E+ ++F        N  K + +
Sbjct: 435 KKFSEWGNNAFFYYFEHRS----SKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEI 490

Query: 430 VQDLLVRFWVNFVIHLNP--THRQPLDWDPMNYENPRLLDIGVE-PKMIDYPYEKTSKFW 486
           +   +V+ W NF  + NP  T      W        + L +  E  +++     +  +FW
Sbjct: 491 LSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFW 550

Query: 487 EEIYDK 492
              + K
Sbjct: 551 TSFFPK 556


>D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precursor
           protein.
          Length = 559

 Score =  117 bits (281), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 118 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 177

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 178 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 237

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 238 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 293

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 294 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 346

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 347 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 405

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 406 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 462

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 463 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 521

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 522 LQPAVGRALKAHRLQFWKK 540


>BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  117 bits (281), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 182 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 241

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 242 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 301

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 302 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 357

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 358 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 410

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 411 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 469

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 470 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 526

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 527 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 585

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 586 LQPAVGRALKAHRLQFWKK 604


>BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  117 bits (281), Expect = 1e-25
 Identities = 141/546 (25%), Positives = 220/546 (40%), Gaps = 67/546 (12%)

Query: 6   LVMLFLIPGTEQNVI-SIAQGKIRGR---VRDGYVT-YGGIPYGSLML-KGRFKQAGIAP 59
           L ML     TE ++I +   GK+RG    V  G VT + GIPY    L + RFK+     
Sbjct: 19  LCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLT 78

Query: 60  VWPNIRE------------------FHESRC--STTSAAEECLQLDVNVPTSAAPTWPVL 99
            W +I                    FH S      T  +E+CL L+V +P        VL
Sbjct: 79  KWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVL 138

Query: 100 VWVTGSD-----GSYH--SGQLVKK--GVIVVIVRHRLGAPGFLCY--ERDIPGNAGAKD 148
           +W+ G        S H   G+ + +   VIVV + +R+GA GFL      + PGN G  D
Sbjct: 139 IWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFD 198

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
              AL WV+ NI AF GNP  V + G+  GAA V    L+P +  LF   ILQSGS  AP
Sbjct: 199 QQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAP 258

Query: 209 WAFN--YDAKDR----AKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCL 262
           WA    Y+A++R    AK+ G   + + + +    N   +E+ +  +E+    +   L +
Sbjct: 259 WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILL--NEAFVVPYGTPLSV 316

Query: 263 EEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDE--AYI------FSSLLKEFKVIN 314
                 +  F  + P  L    + K   +++G N DE  A++      FS          
Sbjct: 317 NFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRK 376

Query: 315 KLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSA 374
           +  + +    P   +F     +   +  ++D   R      AL     D  F+       
Sbjct: 377 EFQEGLKIFFPGVSEFGKESILFHYTDWVDD--QRPENYREALGDVVGDYNFICPALEFT 434

Query: 375 SYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS-----GRNLDKEDGL 429
              +   +  +FY F H       K P  +  G  H  E+ ++F        N  K + +
Sbjct: 435 KKFSEWGNNAFFYYFEHRS----SKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEI 490

Query: 430 VQDLLVRFWVNFVIHLNP--THRQPLDWDPMNYENPRLLDIGVE-PKMIDYPYEKTSKFW 486
           +   +V+ W NF  + NP  T      W        + L +  E  +++     +  +FW
Sbjct: 491 LSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFW 550

Query: 487 EEIYDK 492
              + K
Sbjct: 551 TSFFPK 556


>AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  117 bits (281), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 182 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 241

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 242 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 301

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 302 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 357

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 358 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 410

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 411 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 469

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 470 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 526

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 527 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 585

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 586 LQPAVGRALKAHRLQFWKK 604


>AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isoform
           1 variant protein.
          Length = 582

 Score =  116 bits (280), Expect = 1e-25
 Identities = 114/439 (25%), Positives = 193/439 (43%), Gaps = 42/439 (9%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 141 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 200

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 201 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 260

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 261 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 316

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 317 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPKELLASADFQPVPSIVGVNNNEF 369

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 370 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 428

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K  A H DEL 
Sbjct: 429 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK--ADHGDELP 485

Query: 416 YLFS---GRNLDK---EDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           ++F    G N  K   E+  +   ++++W NF  + NP       W P+  +  + L + 
Sbjct: 486 FVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLN 544

Query: 470 VEPKMIDYPYEKTSKFWEE 488
           ++P +         +FW++
Sbjct: 545 LQPAVGRALKAHRLQFWKK 563


>AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 571

 Score =  116 bits (278), Expect = 3e-25
 Identities = 124/446 (27%), Positives = 188/446 (42%), Gaps = 48/446 (10%)

Query: 76  SAAEECLQLDVNVPTS--AAPTWPVLVWV------TGSDGSYHSGQLVKKG-VIVVIVRH 126
           S +E+CL L+V  P    A    PV+VWV      TG+  SY    L   G V+VV V++
Sbjct: 119 SVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQY 178

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    +   PGN G  DV+AAL WV++NI  F G+   V V G   G +++  L
Sbjct: 179 RLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERL----DKKRDYVDVFLNATM 241
            L+P+A GLFH  I QSG I  P   +      A+ I   L        + V        
Sbjct: 239 VLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEG 298

Query: 242 EELFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAY 301
           EEL +     NT Y         PL  +   F ++P +L   K   SVP ++G N+ E  
Sbjct: 299 EELVLSKKLKNTIY---------PLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHE-- 347

Query: 302 IFSSLL-KEFKVINKLTK-DISFLLPYELQFLNSREM-NQVSRQIEDIYFRRN----RTM 354
            FS L+ + + +++ + +     +L      L S ++  ++   + D Y   N       
Sbjct: 348 -FSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKC 406

Query: 355 TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDEL 414
            A   +  DV+        + Y     S V+FY F H      + +P   K  A H  E 
Sbjct: 407 QAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK--ADHGAEG 464

Query: 415 AYLFSGRNL------------DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYEN 462
           A++F G  L             +E+  +   ++  W +F    +P  +    W   N + 
Sbjct: 465 AFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFN-QA 523

Query: 463 PRLLDIGVEPKMIDYPYEKTSKFWEE 488
            + L+I   P+      E   +FW E
Sbjct: 524 EQYLEINPVPRAGQKFREAWMQFWSE 549


>AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.
          Length = 835

 Score =  114 bits (275), Expect = 6e-25
 Identities = 108/427 (25%), Positives = 181/427 (42%), Gaps = 48/427 (11%)

Query: 101 WVTGSDGSYHSGQLVKKG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRD 158
           ++ G+   +    L   G VIV  + +RLG  GFL   ++   GN G  D I AL W+ +
Sbjct: 188 YMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSE 247

Query: 159 NIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDR 218
           NI  F G+P R+ + G G GA+ V  L L+  +EGLF   I QSG+ ++ W+ NY     
Sbjct: 248 NIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKY 307

Query: 219 AKVIGERL----DKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLEEPLKNEERFFL 274
            +++  ++    +   + V+        EL  +  +    + +FG  ++  +  ++    
Sbjct: 308 TRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDD---- 363

Query: 275 ETPYDLFVTKKSKSVPMIIGYNSDEAYIF---SSLLKEFKVINKLTKDISFLLPYELQFL 331
             P  L    +  +  M+IG N  E   F   S+  ++    +     +S  +     + 
Sbjct: 364 --PEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYP 421

Query: 332 NSREM--NQVSRQIEDIYFRRNRTM--TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFY 387
             +++    +     D   R N  M    LLA   D  +++    +A  HA   S VYFY
Sbjct: 422 EGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFY 481

Query: 388 TFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----GR------NLDKEDGLVQDLLVRF 437
           TF H      Q E   + + AAH DEL Y+F     G       N  K D ++  +++ +
Sbjct: 482 TFYH----HCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTY 537

Query: 438 WVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKT 482
           W NF                IH  P   + + W   N +  + L IG++P++ D      
Sbjct: 538 WTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANK 597

Query: 483 SKFWEEI 489
             FW E+
Sbjct: 598 VAFWLEL 604


>BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.
          Length = 828

 Score =  113 bits (272), Expect = 1e-24
 Identities = 112/442 (25%), Positives = 188/442 (42%), Gaps = 54/442 (12%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 301 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 360

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 417

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 418 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 474

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKED 427
           A   S  YFY F H  +  + K      S AAH DE+ Y+F             N  K D
Sbjct: 475 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKND 530

Query: 428 GLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEP 472
            ++  +++ +W NF                IH      + + W   N  +   L IG++P
Sbjct: 531 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP 590

Query: 473 KMIDYPYEKTSKFWEEIYDKYY 494
           ++ D+       FW+ +    Y
Sbjct: 591 RVRDHYRATKVAFWKHLVPHLY 612


>AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 828

 Score =  113 bits (272), Expect = 1e-24
 Identities = 112/442 (25%), Positives = 188/442 (42%), Gaps = 54/442 (12%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 301 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 360

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 417

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 418 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 474

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKED 427
           A   S  YFY F H  +  + K      S AAH DE+ Y+F             N  K D
Sbjct: 475 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKND 530

Query: 428 GLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEP 472
            ++  +++ +W NF                IH      + + W   N  +   L IG++P
Sbjct: 531 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP 590

Query: 473 KMIDYPYEKTSKFWEEIYDKYY 494
           ++ D+       FW+ +    Y
Sbjct: 591 RVRDHYRATKVAFWKHLVPHLY 612


>AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 848

 Score =  113 bits (272), Expect = 1e-24
 Identities = 112/442 (25%), Positives = 188/442 (42%), Gaps = 54/442 (12%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 321 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 380

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 381 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 437

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 438 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 494

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKED 427
           A   S  YFY F H  +  + K      S AAH DE+ Y+F             N  K D
Sbjct: 495 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKND 550

Query: 428 GLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEP 472
            ++  +++ +W NF                IH      + + W   N  +   L IG++P
Sbjct: 551 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP 610

Query: 473 KMIDYPYEKTSKFWEEIYDKYY 494
           ++ D+       FW+ +    Y
Sbjct: 611 RVRDHYRATKVAFWKHLVPHLY 632


>AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.
          Length = 682

 Score =  113 bits (272), Expect = 1e-24
 Identities = 112/442 (25%), Positives = 188/442 (42%), Gaps = 54/442 (12%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 35  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 94

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 95  QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 154

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 155 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 214

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 215 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 271

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 272 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 328

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKED 427
           A   S  YFY F H  +  + K      S AAH DE+ Y+F             N  K D
Sbjct: 329 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKND 384

Query: 428 GLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEP 472
            ++  +++ +W NF                IH      + + W   N  +   L IG++P
Sbjct: 385 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP 444

Query: 473 KMIDYPYEKTSKFWEEIYDKYY 494
           ++ D+       FW+ +    Y
Sbjct: 445 RVRDHYRATKVAFWKHLVPHLY 466


>AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HNL3
           protein.
          Length = 828

 Score =  113 bits (271), Expect = 2e-24
 Identities = 111/442 (25%), Positives = 187/442 (42%), Gaps = 54/442 (12%)

Query: 97  PVLVWVTGSDGSYHSGQLVKKG-------VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G      +G ++          VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 301 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 360

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 417

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 418 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 474

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GRNLDKED 427
           A   S  YFY F H  +  + K      S AAH DE+ Y+F             N  K D
Sbjct: 475 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKND 530

Query: 428 GLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLLDIGVEP 472
            ++  +++ +W NF                IH      + + W   N  +   L IG++P
Sbjct: 531 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP 590

Query: 473 KMIDYPYEKTSKFWEEIYDKYY 494
           ++ D+       FW+ +    Y
Sbjct: 591 RVRDHYRATKVAFWKHLVPHLY 612


>AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase
           hBr2 protein.
          Length = 565

 Score =  109 bits (263), Expect = 2e-23
 Identities = 119/446 (26%), Positives = 179/446 (40%), Gaps = 38/446 (8%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV++NI  F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFIK 247
           +P+A+ LFH  I +SG  L       D KD A+ I      K     V ++   ++   +
Sbjct: 233 SPLAKNLFHRAISESGVALTAALVKKDMKDTAQQIAVFAGCKSTTSAVLVHCLRQKTEDE 292

Query: 248 SSESNTPYFSFGL-CLEEPLKNEERFFLET----------PYDLFVTKKSKSVPMIIGYN 296
             E +     F L  L +P   E   FL T          P ++   KK  SVP IIG N
Sbjct: 293 LLEVSLKLKFFTLDLLGDP--RESYPFLPTVVDGVLLPKMPQEILAEKKFNSVPYIIGIN 350

Query: 297 SDE-AYIFSSLLKEFKVINKL-TKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRN--- 351
             E  ++   ++      +KL  K  S LL       N  E  +++    + Y       
Sbjct: 351 KQEFGWLLPMMMGYPLSEDKLDQKTASSLLWKSYPIANIPE--ELTPLASEKYLGGTDDP 408

Query: 352 -RTMTALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAH 410
            +     L    DV F       A +H    +  Y Y F +        +P  Q     H
Sbjct: 409 VKKKALFLDMLGDVVFGVPSVTVARHHRDAGAPTYMYEFQYHPSFSSDMKP--QTVVGDH 466

Query: 411 SDELAYLFSGRNL----DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLL 466
            DEL  +F    L     +E+  +  ++++ W NF    NP  +    W P   +    L
Sbjct: 467 GDELFSVFGAPFLKGGASEEEIRLSKMMMKLWANFARSGNPMGKGCSSW-PAYDQKEGYL 525

Query: 467 DIGVEPKMIDYPYEKTSKFWEEIYDK 492
            IG+  +       K   FW E+  K
Sbjct: 526 QIGIPTQPAQKLKSKEMAFWTELLAK 551


>BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.
          Length = 518

 Score =  109 bits (262), Expect = 2e-23
 Identities = 102/363 (28%), Positives = 165/363 (45%), Gaps = 33/363 (9%)

Query: 79  EECLQLDVNVPTSA----APTWPVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHR 127
           E+CL L+V VPT      +   PV+V++ G       G+   G ++     VIV+ + +R
Sbjct: 139 EDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYR 198

Query: 128 LGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALT 186
           +G  GFL   ++   GN G  D I AL WV +NI  F G+P R+ V G G GA+ V  LT
Sbjct: 199 VGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT 258

Query: 187 LTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATME 242
           L+  +EGLF   I+QSGS L+ WA NY       ++ +++        D VD     + +
Sbjct: 259 LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAK 318

Query: 243 ELFIKSSESNTPYFSFGLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYN 296
           EL  +  +    + +FG  ++ + + ++    +E      YD+ +   + + +  + G  
Sbjct: 319 ELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDVMLGVNQGEGLKFVEGVV 378

Query: 297 SDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMT 355
             E  + S    ++ V N +  D  +  P     L    +         D    R +T+ 
Sbjct: 379 DPEDGV-SGTDFDYSVSNFV--DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLV 435

Query: 356 ALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
           AL   H+   ++     +A  HA   S  YFY F H  +  + K      S AAH DE+ 
Sbjct: 436 ALFTDHQ---WVEPSVVTADLHARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVP 488

Query: 416 YLF 418
           Y+F
Sbjct: 489 YVF 491


>S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipase
           protein.
          Length = 742

 Score =  107 bits (258), Expect = 7e-23
 Identities = 117/443 (26%), Positives = 196/443 (44%), Gaps = 62/443 (13%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 93  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 152

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 153 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 212

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 213 ESAGGASVSLQTLSPYNKGLIRAAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 267

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +E F    P +L+   
Sbjct: 268 VGDAARMAQCLKVTDPAAVTVAYKVPLAGLEYPMLHYVGFVPVIDEDFIPADPINLYA-- 325

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 326 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 382

Query: 343 IEDIYFR-------RNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHLG 393
             D+Y         +      ++ +  DV FL     + + H   A S+  Y Y FSH  
Sbjct: 383 TFDVYTESWAQDPSQENKKKIVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS 442

Query: 394 EVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNPT 448
            + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P 
Sbjct: 443 RMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVFKAMIAYWTNFAKTGDPN 498

Query: 449 ---HRQPLDWDPMNYENPRLLDI 468
                 P  W+P   EN   L+I
Sbjct: 499 MGDSAVPTHWEPYTTENSGYLEI 521


>X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for
           bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
          Length = 745

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 385

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 386 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 444

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 445 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 500

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 501 NMGDSAVPTHWEPYTTENSGYLEI 524


>M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 385

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 386 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 444

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 445 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 500

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 501 NMGDSAVPTHWEPYTTENSGYLEI 524


>M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase
           protein.
          Length = 747

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 385

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 386 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 444

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 445 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 500

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 501 NMGDSAVPTHWEPYTTENSGYLEI 524


>M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipase
           protein.
          Length = 742

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 93  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 152

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 153 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 212

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 213 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 267

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 268 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 325

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 326 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 382

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 383 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 441

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 442 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 497

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 498 NMGDSAVPTHWEPYTTENSGYLEI 521


>AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase
           (bile salt-stimulated lipase) protein.
          Length = 756

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 385

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 386 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 444

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 445 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 500

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 501 NMGDSAVPTHWEPYTTENSGYLEI 524


>AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lipase
           oncofetal isoform protein.
          Length = 612

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 73  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 132

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 133 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 192

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 193 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 247

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 248 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 305

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 306 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 362

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 363 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 421

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 422 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 477

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 478 NMGDSAVPTHWEPYTTENSGYLEI 501


>AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  106 bits (254), Expect = 2e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 64/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEEDFYKLVSEFTITKGL-RGAKT 385

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 386 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 444

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 445 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 500

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 501 NMGDSAVPTHWEPYTTENSGYLEI 524


>BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.
          Length = 722

 Score =  104 bits (250), Expect = 6e-22
 Identities = 118/444 (26%), Positives = 198/444 (44%), Gaps = 65/444 (14%)

Query: 74  TTSAAEECLQLDVNVPTS---AAPTWPVLVWVTGSD---GSYHSG-----------QLVK 116
           +T   E+CL L++ VP      +   PV++W+ G     GS H             ++  
Sbjct: 96  STYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIAT 155

Query: 117 KG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAG 174
           +G VIVV   +R+G  GFL   + ++PGN G +D   A+ WV+ NI AF G+P  + + G
Sbjct: 156 RGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFG 215

Query: 175 QGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVD 234
           +  G A V   TL+P  +GL    I QSG  L+PW    +    AK + E++        
Sbjct: 216 ESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVG-----CP 270

Query: 235 VFLNATMEE-LFIKSSESNTPYFSFGLC-LEEPLKN--------EERFFLETPYDLFVTK 284
           V   A M + L +    + T  +   L  LE P+ +        +  F    P +L+   
Sbjct: 271 VGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYA-- 328

Query: 285 KSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYEL--QFLNSREMNQVSRQ 342
            +  +  I G N+ + +IF+S+  +   INK  K ++    Y+L  +F  ++ + + ++ 
Sbjct: 329 NAADIDYIAGTNNMDGHIFASI--DMPAINKGNKKVTEDF-YKLVSEFTITKGL-RGAKT 384

Query: 343 IEDIY--------FRRNRTMTALLAYHRDVYFLSHVYRSASYHA--AVSSLVYFYTFSHL 392
             D+Y         + N+  T ++ +  DV FL     + + H   A S+  Y Y FSH 
Sbjct: 385 TFDVYTESWAQDPSQENKKKT-VVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHP 443

Query: 393 GEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGLVQDLLVRFWVNFVIHLNP 447
             + V      +  GA H+D++ Y+F     +      +D  V   ++ +W NF    +P
Sbjct: 444 SRMPVYP----KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDP 499

Query: 448 T---HRQPLDWDPMNYENPRLLDI 468
                  P  W+P   EN   L+I
Sbjct: 500 NMGDSAVPTHWEPYTTENSGYLEI 523


>AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase
           hBr3 protein.
          Length = 567

 Score =  104 bits (250), Expect = 6e-22
 Identities = 109/444 (24%), Positives = 180/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI  F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVL 232

Query: 188 TPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFIK 247
           +P+A+ LFH  I +SG  L       D K  A ++      K     V ++   ++   +
Sbjct: 233 SPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDE 292

Query: 248 SSESNTPYFSFGLCLEEPLKNEERF---------FLETPYDLFVTKKSKSVPMIIGYNSD 298
             E++     F L L    K    F           + P ++   K   +VP I+G N  
Sbjct: 293 LLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQ 352

Query: 299 E-AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTAL 357
           E  +I  +L+       KL +  +  L ++  +   +    +   + + Y      +T  
Sbjct: 353 EFGWIIPTLMGYPLAEGKLDQKTANSLLWK-SYPTLKISENMIPVVAEKYLGGTDDLTKK 411

Query: 358 LAYHRD-----VYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
               +D     V+ +  V  S S+  A +S  Y Y F +     V +    +     H D
Sbjct: 412 KDLFQDLMADVVFGVPSVIVSRSHRDAGAS-TYMYEFEYRPSF-VSRHEDPKAVIGDHGD 469

Query: 413 ELAYLFSGRNL----DKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           E+  +F    L     +E+  +  ++++FW NF  + NP       W     +    L I
Sbjct: 470 EIFSVFGSPFLKDGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPRNMTKKEGYLKI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW E+  K
Sbjct: 530 GASTQAAQRLKDKEVSFWAELRAK 553


>BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.
          Length = 587

 Score =  104 bits (249), Expect = 8e-22
 Identities = 106/433 (24%), Positives = 186/433 (42%), Gaps = 46/433 (10%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 162 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 221

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 222 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 281

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 282 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 337

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 338 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 390

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 391 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 449

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K     +D + 
Sbjct: 450 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK-----ADHVK 503

Query: 416 YLFSGRNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMI 475
           +      L ++       ++++W NF  + NP       W P+  +  + L + ++P + 
Sbjct: 504 FTEEEEQLSRK-------MMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLNLQPAVG 555

Query: 476 DYPYEKTSKFWEE 488
                   +FW++
Sbjct: 556 RALKAHRLQFWKK 568


>BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.
          Length = 586

 Score =  104 bits (249), Expect = 8e-22
 Identities = 106/433 (24%), Positives = 186/433 (42%), Gaps = 46/433 (10%)

Query: 76  SAAEECLQLDVNVPTSA--APTWPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRH 126
           S +E+CL L +  P  +      PV+VW+ G        S + G ++   + V+VVI+++
Sbjct: 161 SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQY 220

Query: 127 RLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEAL 185
           RLG  GF    ++   GN G  D +AAL WV+ NI  F GNP RV + G+  G   V +L
Sbjct: 221 RLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 280

Query: 186 TLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELF 245
            ++P+++GLFHG I++SG  L P      A   + V+        D VD    A +  L 
Sbjct: 281 VVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL--SACDQVD--SEALVGCLR 336

Query: 246 IKSSESNTPYFSFGLCLEEPLKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDE- 299
            KS E         L + +P K      +  F    P +L  +   + VP I+G N++E 
Sbjct: 337 GKSKEEI-------LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEF 389

Query: 300 AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLA 359
            ++   +++ +    ++ ++ S     ++  L           + + Y   N     L A
Sbjct: 390 GWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPT-FGDLLREEYIGDNGDPQTLQA 448

Query: 360 YHR----DVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELA 415
             +    D  F+    + A +  +  + VYFY F H         P   K     +D + 
Sbjct: 449 QFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMK-----ADHVK 502

Query: 416 YLFSGRNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMI 475
           +      L ++       ++++W NF  + NP       W P+  +  + L + ++P + 
Sbjct: 503 FTEEEEQLSRK-------MMKYWANFARNGNPNGEGLPHW-PLFDQEEQYLQLNLQPAVG 554

Query: 476 DYPYEKTSKFWEE 488
                   +FW++
Sbjct: 555 RALKAHRLQFWKK 567


>X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage
           serine-esterase 1 protein.
          Length = 503

 Score =  103 bits (248), Expect = 1e-21
 Identities = 107/443 (24%), Positives = 178/443 (40%), Gaps = 31/443 (6%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 50  SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 109

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 110 GIWGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 169

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 170 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 229

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 230 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 289

Query: 298 DE-AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM-- 354
            E  ++   L+       +L +  +  L ++   L       +    E      + T+  
Sbjct: 290 QEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKK 349

Query: 355 -TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDE 413
               L    DV F       A  H    +  Y Y F +        +P  +     H DE
Sbjct: 350 KDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGDE 407

Query: 414 LAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           L  +F          +E+  +  ++++FW NF  + NP       W   N +    L IG
Sbjct: 408 LFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQIG 466

Query: 470 VEPKMIDYPYEKTSKFWEEIYDK 492
              +      +K   FW  ++ K
Sbjct: 467 ANTQAAQKLKDKEVAFWTNLFAK 489


>BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 566

 Score =  103 bits (248), Expect = 1e-21
 Identities = 107/443 (24%), Positives = 178/443 (40%), Gaps = 31/443 (6%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM-- 354
            E  ++   L+       +L +  +  L ++   L       +    E      + T+  
Sbjct: 353 QEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKK 412

Query: 355 -TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDE 413
               L    DV F       A  H    +  Y Y F +        +P  +     H DE
Sbjct: 413 KDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGDE 470

Query: 414 LAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           L  +F          +E+  +  ++++FW NF  + NP       W   N +    L IG
Sbjct: 471 LFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQIG 529

Query: 470 VEPKMIDYPYEKTSKFWEEIYDK 492
              +      +K   FW  ++ K
Sbjct: 530 ANTQAAQKLKDKEVAFWTNLFAK 552


>S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholesterol
           acyltransferase protein.
          Length = 568

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 114 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 173

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 174 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 233

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 234 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 293

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 294 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 353

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 354 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 413

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 414 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 471

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 472 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 530

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 531 GANTQAAQKLKDKEVAFWTNLFAK 554


>M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.
          Length = 507

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 53  SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 112

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 113 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 172

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 173 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 232

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 233 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 292

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 293 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 352

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 353 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 410

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 411 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 469

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 470 GANTQAAQKLKDKEVAFWTNLFAK 493


>D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester
           hydrolase protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  103 bits (246), Expect = 2e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 353 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 412

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 413 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 470

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 471 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 529

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLFAK 553


>L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.
          Length = 566

 Score =  102 bits (245), Expect = 3e-21
 Identities = 107/443 (24%), Positives = 178/443 (40%), Gaps = 31/443 (6%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE-AYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM-- 354
            E  ++   L+       +L +  +  L ++   L       +    E      + T+  
Sbjct: 353 QEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKK 412

Query: 355 -TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDE 413
               L    DV F       A  H    +  Y Y F +        +P  +     H DE
Sbjct: 413 KDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGDE 470

Query: 414 LAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           L  +F          +E+  +  ++++FW NF  + NP       W   N +    L IG
Sbjct: 471 LFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQIG 529

Query: 470 VEPKMIDYPYEKTSKFWEEIYDK 492
              +      +K   FW  ++ K
Sbjct: 530 ANTQAGQKLKDKEVAFWTNLFAK 552


>AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HNL3s
           protein.
          Length = 558

 Score =  102 bits (244), Expect = 3e-21
 Identities = 94/341 (27%), Positives = 154/341 (45%), Gaps = 29/341 (8%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLE- 263
           WA NY       ++ +++        D VD     + +EL  +  +    + +FG  ++ 
Sbjct: 321 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 380

Query: 264 EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTK 318
           + + ++    +E      YD+ +   + + +  + G    E  + S    ++ V N +  
Sbjct: 381 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGV-SGTDFDYSVSNFV-- 437

Query: 319 DISFLLPYELQFLNSR-EMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYH 377
           D  +  P     L    +         D    R +T+ AL   H+   ++     +A  H
Sbjct: 438 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ---WVEPSVVTADLH 494

Query: 378 AAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLF 418
           A   S  YFY F H  +  + K      S AAH DE+ Y+F
Sbjct: 495 ARYGSPTYFYAFYHHCQ-SLMKPAW---SDAAHGDEVPYVF 531


>L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.
          Length = 568

 Score =  101 bits (243), Expect = 4e-21
 Identities = 107/444 (24%), Positives = 179/444 (40%), Gaps = 32/444 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 114 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 173

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 174 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 233

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 234 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 293

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 294 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 353

Query: 298 DE-AYIFSSLLKEFKVI-NKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTM- 354
            E  ++    L  + +   +L +  +  L ++   L       +    E      + T+ 
Sbjct: 354 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVK 413

Query: 355 --TALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSD 412
                L    DV F       A  H    +  Y Y F +        +P  +     H D
Sbjct: 414 KKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGD 471

Query: 413 ELAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDI 468
           EL  +F          +E+  +  ++++FW NF  + NP       W   N +    L I
Sbjct: 472 ELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN-QKEGYLQI 530

Query: 469 GVEPKMIDYPYEKTSKFWEEIYDK 492
           G   +      +K   FW  ++ K
Sbjct: 531 GANTQAGQKLKDKEVAFWTNLFAK 554


>BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.
          Length = 454

 Score =  101 bits (241), Expect = 8e-21
 Identities = 57/139 (41%), Positives = 80/139 (57%), Gaps = 10/139 (7%)

Query: 78  AEECLQLDVNVPTSAA--PTWPVLVW------VTGSDGSYHSGQLV-KKGVIVVIVRHRL 128
           +E+CL L+V  P  A   P  PV+VW      + G+  SY    L  ++ V++V ++HRL
Sbjct: 76  SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRL 135

Query: 129 GAPGFLCYERD-IPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GFL  +     GN G  D +AAL WV++NI AF G+P  V + GQ  GA  +  L +
Sbjct: 136 GIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMM 195

Query: 188 TPMAEGLFHGVILQSGSIL 206
           +P+A GLFH  I QSG+ L
Sbjct: 196 SPLASGLFHRAISQSGTAL 214


>BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.
          Length = 823

 Score =  101 bits (241), Expect = 8e-21
 Identities = 124/503 (24%), Positives = 213/503 (42%), Gaps = 74/503 (14%)

Query: 47  MLKGRFKQAGIAPVW-PNIREFHESRCSTTSAAEECLQLDVNVPT------SAAPTWPVL 99
           ++ GR  +  + PVW  N  +   S     S  E+CL L++ VPT      S  P  PV+
Sbjct: 121 IIDGRLPEV-MLPVWFTNNLDVVSSYVQDQS--EDCLYLNIYVPTEDDIRDSGGPK-PVM 176

Query: 100 VWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIA 151
           V++ G       G+ + G ++     VIV+ V +RLG  GFL   ++   GN G  D+I 
Sbjct: 177 VYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQ 236

Query: 152 ALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAE---------GLFHGVILQS 202
           AL W  +NI  F G+P R+ V G G G + V  LTL+  +E         GLF   I QS
Sbjct: 237 ALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQS 296

Query: 203 GSILAPWAFNYD----AKDRAKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSF 258
           G+ L+ WA ++     A+  A  +G  +    + V+       +EL  +  +    + +F
Sbjct: 297 GTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAF 356

Query: 259 GLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIG-YNSDEAYIFSSLLKEFK 311
           G  ++ + + ++ +  +E      YD+ +   + + +  +    +SD+    S    +F 
Sbjct: 357 GPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDF--DFA 414

Query: 312 VINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVY 371
           V N +  D  +  P     L    +  +     D +    R  T LLA   D  +++   
Sbjct: 415 VSNFV--DNLYGYPEGKDVLR-ETIKFMYTDWADRHNPETRRKT-LLALFTDHQWVAPAV 470

Query: 372 RSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GR 421
            +A  H+   S  YFY F H      Q +     + AAH DE+ Y+              
Sbjct: 471 ATADLHSNFGSPTYFYAFYH----HCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPC 526

Query: 422 NLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLL 466
           N  K D ++  +++ +W NF                IH  P   + + W   + ++   L
Sbjct: 527 NFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYL 586

Query: 467 DIGVEPKMIDYPYEKTSKFWEEI 489
            IG++P++ ++        W E+
Sbjct: 587 HIGLKPRVKEHYRANKVNLWLEL 609


>AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 545

 Score =  101 bits (241), Expect = 8e-21
 Identities = 57/139 (41%), Positives = 80/139 (57%), Gaps = 10/139 (7%)

Query: 78  AEECLQLDVNVPTSAA--PTWPVLVW------VTGSDGSYHSGQLV-KKGVIVVIVRHRL 128
           +E+CL L+V  P  A   P  PV+VW      + G+  SY    L  ++ V++V ++HRL
Sbjct: 217 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRL 276

Query: 129 GAPGFLCYERD-IPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GFL  +     GN G  D +AAL WV++NI AF G+P  V + GQ  GA  +  L +
Sbjct: 277 GIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMM 336

Query: 188 TPMAEGLFHGVILQSGSIL 206
           +P+A GLFH  I QSG+ L
Sbjct: 337 SPLASGLFHRAISQSGTAL 355


>AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.
          Length = 826

 Score =  101 bits (241), Expect = 8e-21
 Identities = 124/503 (24%), Positives = 213/503 (42%), Gaps = 74/503 (14%)

Query: 47  MLKGRFKQAGIAPVW-PNIREFHESRCSTTSAAEECLQLDVNVPT------SAAPTWPVL 99
           ++ GR  +  + PVW  N  +   S     S  E+CL L++ VPT      S  P  PV+
Sbjct: 124 IIDGRLPEV-MLPVWFTNNLDVVSSYVQDQS--EDCLYLNIYVPTEDDIRDSGGPK-PVM 179

Query: 100 VWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIA 151
           V++ G       G+ + G ++     VIV+ V +RLG  GFL   ++   GN G  D+I 
Sbjct: 180 VYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQ 239

Query: 152 ALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAE---------GLFHGVILQS 202
           AL W  +NI  F G+P R+ V G G G + V  LTL+  +E         GLF   I QS
Sbjct: 240 ALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQS 299

Query: 203 GSILAPWAFNYD----AKDRAKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSF 258
           G+ L+ WA ++     A+  A  +G  +    + V+       +EL  +  +    + +F
Sbjct: 300 GTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAF 359

Query: 259 GLCLE-EPLKNEERFFLE----TPYDLFV-TKKSKSVPMIIG-YNSDEAYIFSSLLKEFK 311
           G  ++ + + ++ +  +E      YD+ +   + + +  +    +SD+    S    +F 
Sbjct: 360 GPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDF--DFA 417

Query: 312 VINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVY 371
           V N +  D  +  P     L    +  +     D +    R  T LLA   D  +++   
Sbjct: 418 VSNFV--DNLYGYPEGKDVLR-ETIKFMYTDWADRHNPETRRKT-LLALFTDHQWVAPAV 473

Query: 372 RSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFS----------GR 421
            +A  H+   S  YFY F H      Q +     + AAH DE+ Y+              
Sbjct: 474 ATADLHSNFGSPTYFYAFYH----HCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPC 529

Query: 422 NLDKEDGLVQDLLVRFWVNFV---------------IHLNPTHRQPLDWDPMNYENPRLL 466
           N  K D ++  +++ +W NF                IH  P   + + W   + ++   L
Sbjct: 530 NFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYL 589

Query: 467 DIGVEPKMIDYPYEKTSKFWEEI 489
            IG++P++ ++        W E+
Sbjct: 590 HIGLKPRVKEHYRANKVNLWLEL 612


>M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.
          Length = 454

 Score =  100 bits (239), Expect = 1e-20
 Identities = 107/443 (24%), Positives = 178/443 (40%), Gaps = 32/443 (7%)

Query: 79  EECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRLG 129
           E CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RLG
Sbjct: 1   EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 60

Query: 130 APGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLT 188
             GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L+
Sbjct: 61  IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 120

Query: 189 PMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVI----GERLDKKRDYVDVFLNATMEE 243
           P+A+ LFH  I +SG ++ +      D K  A+ I    G +       V      T EE
Sbjct: 121 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAAMVHCLRQKTEEE 180

Query: 244 LFIKSSESNTPY-FSFGLCLEEP----LKNEERFFLETPYDLFVTKKSKSVPMIIGYNSD 298
           L   + +    Y +++     E        +    L+TP +L   +   +VP ++G N  
Sbjct: 181 LLETTLKIGNSYLWTYRETQRESTLLGTVIDGMLLLKTPEELQRERNFHTVPYMVGINKQ 240

Query: 299 E-AYIFSSLLKEFKVI-NKLTKDISFLL---PYELQFLNSREMNQVSRQIEDIYFRRNRT 353
           E  ++    L  + +   +L +  +  L   P  L  +    + + + +         + 
Sbjct: 241 EFGWLIPMQLMSYPLSEGQLDQKTAMSLLGSPIPLFAIAKELIPEATEKYLGGTDDTVKK 300

Query: 354 MTALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDE 413
              +L    DV F       A  H    +  Y Y F +        +P  +     H DE
Sbjct: 301 KDLILDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKP--KTVIGDHGDE 358

Query: 414 LAYLFSG----RNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIG 469
           L  +F          +E+  +  ++++FW NF  + NP  +    W   N +    L IG
Sbjct: 359 LFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGKGLPHWPEYN-QKEGYLQIG 417

Query: 470 VEPKMIDYPYEKTSKFWEEIYDK 492
              +      +K   FW  ++ K
Sbjct: 418 ANTQAAQKLKDKEVAFWTNLFAK 440


>M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase
           protein.
          Length = 614

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase,
           isoform E4-E5 precursor protein.
          Length = 617

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Yt
           blood group) protein.
          Length = 617

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.
          Length = 546

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (YT
           blood group) protein.
          Length = 617

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase
           isoform E4-E6 precursor variant protein.
          Length = 614

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related
           acetylcholinesterase protein.
          Length = 526

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.
          Length = 617

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.
          Length = 614

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 60/148 (40%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PVLVW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVLVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein
           protein.
          Length = 351

 Score = 95.5 bits (227), Expect = 4e-19
 Identities = 59/175 (33%), Positives = 91/175 (52%), Gaps = 12/175 (6%)

Query: 97  PVLVWVTGSD-----GSYHSGQLVKK--GVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKD 148
           PV+V++ G       G+   G ++     VIV+ + +R+G  GFL   ++   GN G  D
Sbjct: 64  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 123

Query: 149 VIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
            I AL WV +NI  F G+P R+ V G G GA+ V  LTL+  +EGLF   I+QSGS L+ 
Sbjct: 124 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 183

Query: 209 WAFNYDAKDRAKVIGERLD----KKRDYVDVFLNATMEELFIKSSESNTPYFSFG 259
           WA NY   +   ++ +++        D VD     + +EL  +  +    + +FG
Sbjct: 184 WAVNYQPVEYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFG 238


>BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.
          Length = 640

 Score = 95.5 bits (227), Expect = 4e-19
 Identities = 59/148 (39%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 78  AEECLQLDV--NVPTSAAPTWPVLVWVTGSDGSYHSGQ----------LVK-KGVIVVIV 124
           +E+CL L+V    P   +PT PV+VW+ G  G ++SG           LV+ +  ++V +
Sbjct: 124 SEDCLYLNVWTPYPRPTSPT-PVIVWIYG--GGFYSGASSLDVYDGRFLVQAERTVLVSM 180

Query: 125 RHRLGAPGFLCY--ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMV 182
            +R+GA GFL     R+ PGN G  D   AL WV++N+ AF G+P  V + G+  GAA V
Sbjct: 181 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240

Query: 183 EALTLTPMAEGLFHGVILQSGSILAPWA 210
               L+P + GLFH  +LQSG+   PWA
Sbjct: 241 GMHLLSPPSRGLFHRAVLQSGAPNGPWA 268


>AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-related
           protein protein.
          Length = 288

 Score = 92.3 bits (219), Expect = 4e-18
 Identities = 53/139 (38%), Positives = 75/139 (53%), Gaps = 10/139 (7%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 115 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 174

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +   PGN G  D +AALHWV+DNI +F GNP  V + G   G   V  L L
Sbjct: 175 GIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVL 234

Query: 188 TPMAEGLFHGVILQSGSIL 206
           +P+A+ LFH  I +SG  L
Sbjct: 235 SPLAKNLFHRAISESGVAL 253


>AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
           LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
          Length = 367

 Score = 91.5 bits (217), Expect = 6e-18
 Identities = 91/370 (24%), Positives = 158/370 (42%), Gaps = 25/370 (6%)

Query: 150 IAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSIL-AP 208
           +AAL WV++NI AF G+P  V + GQ  GA  +  L ++P+A GLFH  I QSG+ L  P
Sbjct: 1   MAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRP 60

Query: 209 WAFNYD---AKDRAKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLEEP 265
           +  +     AK  A + G   +  +  V+     +  ++   S++      +F    EE 
Sbjct: 61  FITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEI 120

Query: 266 LKN-----EERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINK-LTKD 319
           + +     +     + P  L    K  SVP ++G N+ E       + +F +  + + K+
Sbjct: 121 IWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKE 180

Query: 320 ISFLLPYELQFLNSREMNQVSRQIEDIYFRRNR-----TMTALLAYHRDVYFLSHVYRSA 374
               + +  + L +    QV   +E+     N          ++   +D  F+    ++A
Sbjct: 181 TITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTA 240

Query: 375 SYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLF-----SGRNLDKEDGL 429
            YH      VY Y F H    G+  +P  +  GA H DE+ +LF     +G ++ KE  L
Sbjct: 241 HYHRDAGLPVYLYEFEHHAR-GIIVKP--RTDGADHGDEMYFLFGGPFATGLSMGKEKAL 297

Query: 430 VQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
              ++ ++W NF    NP       W P   ++ + L +    ++     EK   FW  +
Sbjct: 298 SLQMM-KYWANFARTGNPNDGNLPCW-PRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSL 355

Query: 490 YDKYYYSRNR 499
           Y      + R
Sbjct: 356 YQSQRPEKQR 365


>AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase
           hBr1 protein.
          Length = 429

 Score = 90.2 bits (214), Expect = 1e-17
 Identities = 70/242 (28%), Positives = 112/242 (46%), Gaps = 20/242 (8%)

Query: 78  AEECLQLDVNVPTSAAPT--WPVLVWVTGSD-----GSYHSGQLVK--KGVIVVIVRHRL 128
           +E+CL L++  P         PV+VW+ G        S + G  +   + V+VV +++RL
Sbjct: 113 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 172

Query: 129 GAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTL 187
           G  GF    +    GN G  D +AAL WV+DNI +F GNP  V + G+  G   V  L L
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 232

Query: 188 TPMAEGLFHGVILQSG-SILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFI 246
           +P+A+ LFH  I +SG ++ +      D K  A+ I      K     V ++   ++   
Sbjct: 233 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 292

Query: 247 KSSESNTPYFSFGLCLE------EPLKN---EERFFLETPYDLFVTKKSKSVPMIIGYNS 297
           +  E+        L L+      +PL     +    L+TP +L   +   +VP ++G N 
Sbjct: 293 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 352

Query: 298 DE 299
            E
Sbjct: 353 QE 354


>AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40219 fis, clone TESTI2021637, moderately
           similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
           3.1.1.1). ).
          Length = 207

 Score = 87.8 bits (208), Expect = 8e-17
 Identities = 48/109 (44%), Positives = 63/109 (57%), Gaps = 2/109 (1%)

Query: 102 VTGSDGSYHSGQLVKKG-VIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDN 159
           +TG+  SY    L   G V+VV V++RLG  GF    +   PGN G  DV+AAL WV++N
Sbjct: 10  ITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQEN 69

Query: 160 IIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAP 208
           I  F G+   V V G   G +++  L L+P+A GLFH  I QSG I  P
Sbjct: 70  IAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTP 118


>BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.
          Length = 151

 Score = 83.8 bits (198), Expect = 1e-15
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 117 KGVIVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQ 175
           + V+VV +++RLG  GF    +   PGN G  D +AALHWV+DNI +F GNP  V + G 
Sbjct: 26  ENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAALHWVQDNIASFGGNPGSVTIFGG 85

Query: 176 GFGAAMVEALTLTPMAEGLFHGVILQSGSIL 206
             G   V  L L+P+A+ LFH  I +SG  L
Sbjct: 86  SAGGESVSVLVLSPLAKNLFHRAISESGVAL 116


>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
          Length = 2767

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 70   SRCSTT-SAAEECLQLDVNVPTSAAPTWPVLVWVTG------SDG--SYHSGQLVKKG-V 119
            +R ST+   +E+CL L+V +P + AP   VLV+         S+G  +     L   G +
Sbjct: 2268 TRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNL 2327

Query: 120  IVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFG 178
            IVV   +R+G  GFL     ++ GN G  D +AAL WV+ +I  F G+P RV +A    G
Sbjct: 2328 IVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGG 2387

Query: 179  A--AMVEALTLTPMAEGLFHGVILQSGSILAPWA 210
            A  A +  LT       LF   +L  GS L+P A
Sbjct: 2388 ADVASIHLLTARATNSQLFRRAVLMGGSALSPAA 2421


>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
          Length = 2768

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 70   SRCSTT-SAAEECLQLDVNVPTSAAPTWPVLVWVTG------SDG--SYHSGQLVKKG-V 119
            +R ST+   +E+CL L+V +P + AP   VLV+         S+G  +     L   G +
Sbjct: 2269 TRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNL 2328

Query: 120  IVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFG 178
            IVV   +R+G  GFL     ++ GN G  D +AAL WV+ +I  F G+P RV +A    G
Sbjct: 2329 IVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGG 2388

Query: 179  A--AMVEALTLTPMAEGLFHGVILQSGSILAPWA 210
            A  A +  LT       LF   +L  GS L+P A
Sbjct: 2389 ADVASIHLLTARATNSQLFRRAVLMGGSALSPAA 2422


>BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for
           IMAGE:40133565) protein.
          Length = 422

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 70  SRCSTT-SAAEECLQLDVNVPTSAAPTWPVLVWVTG------SDG--SYHSGQLVKKG-V 119
           +R ST+   +E+CL L+V +P + AP   VLV+         S+G  +     L   G +
Sbjct: 231 TRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNL 290

Query: 120 IVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFG 178
           IVV   +R+G  GFL     ++ GN G  D +AAL WV+ +I  F G+P RV +A    G
Sbjct: 291 IVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGG 350

Query: 179 A--AMVEALTLTPMAEGLFHGVILQSGSILAPWA 210
           A  A +  LT       LF   +L  GS L+P A
Sbjct: 351 ADVASIHLLTARATNSQLFRRAVLMGGSALSPAA 384


>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
          Length = 1124

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 70  SRCSTT-SAAEECLQLDVNVPTSAAPTWPVLVWVTG------SDG--SYHSGQLVKKG-V 119
           +R ST+   +E+CL L+V +P + AP   VLV+         S+G  +     L   G +
Sbjct: 625 TRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNL 684

Query: 120 IVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFG 178
           IVV   +R+G  GFL     ++ GN G  D +AAL WV+ +I  F G+P RV +A    G
Sbjct: 685 IVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGG 744

Query: 179 A--AMVEALTLTPMAEGLFHGVILQSGSILAPWA 210
           A  A +  LT       LF   +L  GS L+P A
Sbjct: 745 ADVASIHLLTARATNSQLFRRAVLMGGSALSPAA 778


>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
            variant protein.
          Length = 1574

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 13/154 (8%)

Query: 70   SRCSTT-SAAEECLQLDVNVPTSAAPTWPVLVWVTG------SDG--SYHSGQLVKKG-V 119
            +R ST+   +E+CL L+V +P + AP   VLV+         S+G  +     L   G +
Sbjct: 1075 TRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNL 1134

Query: 120  IVVIVRHRLGAPGFLCY-ERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFG 178
            IVV   +R+G  GFL     ++ GN G  D +AAL WV+ +I  F G+P RV +A    G
Sbjct: 1135 IVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGG 1194

Query: 179  A--AMVEALTLTPMAEGLFHGVILQSGSILAPWA 210
            A  A +  LT       LF   +L  GS L+P A
Sbjct: 1195 ADVASIHLLTARATNSQLFRRAVLMGGSALSPAA 1228


>AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.
          Length = 550

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 32/165 (19%)

Query: 350 RNRTMTALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAA 409
           R +T+ AL   H+   +++    +A  HA   S VYFYTF H      Q E   + + AA
Sbjct: 162 RRKTLLALFTDHQ---WVAPAVATAKLHADYQSPVYFYTFYH----HCQAEGRPEWADAA 214

Query: 410 HSDELAYLFS----GR------NLDKEDGLVQDLLVRFWVNFV---------------IH 444
           H DEL Y+F     G       N  K D ++  +++ +W NF                IH
Sbjct: 215 HGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIH 274

Query: 445 LNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
             P   + + W   N +  + L IG++P++ D        FW E+
Sbjct: 275 TKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLEL 319


>AK074522-1|BAC11039.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90041 fis, clone HEMBA1002167, highly similar to
           Rattus norvegicus neuroligin I mRNA. ).
          Length = 509

 Score = 38.7 bits (86), Expect = 0.047
 Identities = 36/165 (21%), Positives = 66/165 (40%), Gaps = 32/165 (19%)

Query: 350 RNRTMTALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAA 409
           R +T+ AL   H+   +++    +A  H+   S  YFY F H      Q +     + AA
Sbjct: 138 RRKTLLALFTDHQ---WVAPAVATADLHSNFGSPTYFYAFYH----HCQTDQVPAWADAA 190

Query: 410 HSDELAYLFS----------GRNLDKEDGLVQDLLVRFWVNFV---------------IH 444
           H DE+ Y+              N  K D ++  +++ +W NF                IH
Sbjct: 191 HGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIH 250

Query: 445 LNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEI 489
             P   + + W   + ++   L IG++P++ ++        W E+
Sbjct: 251 TKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 295


>AY533507-1|AAS45401.1|  796|Homo sapiens ARC/mediator
           transcriptional coactivator subunit protein.
          Length = 796

 Score = 34.7 bits (76), Expect = 0.77
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 72  CSTTSAAEECLQLDVNVPTSAAPTWPVLVWVTGSDGSYHSGQLVKKGVIVVIVRHRLGAP 131
           C+  SAA       V  PT A+ T PVL   T   GS  SG+  K+      V  ++GA 
Sbjct: 707 CAAASAAPGPGAAPVGAPTPASTTCPVLARTTSPSGSTASGK-TKERRRGPCVSRKMGAS 765

Query: 132 GFLC 135
            FLC
Sbjct: 766 LFLC 769


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.322    0.139    0.421 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,807,659
Number of Sequences: 224733
Number of extensions: 3215705
Number of successful extensions: 5299
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4981
Number of HSP's gapped (non-prelim): 204
length of query: 503
length of database: 73,234,838
effective HSP length: 93
effective length of query: 410
effective length of database: 52,334,669
effective search space: 21457214290
effective search space used: 21457214290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)

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