SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000772-TA|BGIBMGA000772-PA|IPR002018|Carboxylesterase,
type B
         (567 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.        151   5e-36
BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.        151   5e-36
AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5 prot...   151   5e-36
BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7 prot...   132   2e-30
AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens ...   132   2e-30
AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase ...   132   4e-30
AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo pr...   127   9e-29
BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.        126   2e-28
AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase ...   126   3e-28
Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.      122   3e-27
U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.      122   3e-27
D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precurso...   122   3e-27
BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2 (int...   122   3e-27
AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2 (int...   122   3e-27
AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isof...   122   3e-27
BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1 (mon...   120   2e-26
S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholester...   118   4e-26
M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.      118   4e-26
D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.      118   4e-26
BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1 (mon...   118   4e-26
AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.              118   4e-26
AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b p...   118   4e-26
AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a p...   118   4e-26
AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b p...   118   4e-26
AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a p...   118   4e-26
L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.      118   6e-26
M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase pro...   118   7e-26
M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.                  118   7e-26
M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.                  118   7e-26
BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase p...   118   7e-26
L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.      117   1e-25
BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.        115   4e-25
AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.    115   4e-25
M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase prot...   115   5e-25
BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase, i...   115   5e-25
BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Y...   115   5e-25
BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.        115   5e-25
AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (Y...   115   5e-25
AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase is...   115   5e-25
AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related acety...   115   5e-25
AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.             115   5e-25
AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.             115   5e-25
BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.        114   9e-25
BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.    114   9e-25
AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester hydro...   113   1e-24
BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked ...   111   5e-24
BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked ...   111   5e-24
AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.        111   5e-24
AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens ...   111   6e-24
AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase ...   111   8e-24
BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked ...   110   1e-23
AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.        110   1e-23
AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.    110   1e-23
BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.        109   3e-23
BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.        109   3e-23
BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.       108   6e-23
BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.         105   3e-22
AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-relate...   105   3e-22
AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.        103   2e-21
AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform pr...   103   2e-21
BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.        102   4e-21
AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HN...   102   4e-21
BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.    101   7e-21
M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.      101   9e-21
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.          99   2e-20
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.       100   3e-20
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor...   100   3e-20
X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for ...    99   4e-20
M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase pro...    99   4e-20
M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase prot...    99   4e-20
M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipas...    99   4e-20
AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase (...    99   4e-20
AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lip...    99   4e-20
AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase p...    99   4e-20
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.          97   1e-19
AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.                97   1e-19
X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage serin...    97   2e-19
S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipas...    97   2e-19
BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for IM...    97   2e-19
AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo pr...    86   3e-16
AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.     86   3e-16
AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform pr...    86   4e-16
AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.     86   4e-16
AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HN...    82   6e-15
M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.       77   2e-13
BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein pr...    73   3e-12
AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens ...    69   3e-11
BC009706-1|AAH09706.1|  150|Homo sapiens CES1 protein protein.         64   2e-09
BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.         63   2e-09
AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens ...    63   2e-09
BC025347-1|AAH25347.1|  441|Homo sapiens KIAA0692 protein protein.     37   0.17 
BC001530-1|AAH01530.2|  441|Homo sapiens KIAA0692 protein protein.     37   0.17 
AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.     37   0.17 
AB014592-1|BAA31667.1|  783|Homo sapiens KIAA0692 protein protein.     37   0.17 
BC043157-1|AAH43157.2|  938|Homo sapiens KIAA0692 protein protein.     36   0.38 
AK074522-1|BAC11039.1|  509|Homo sapiens protein ( Homo sapiens ...    36   0.51 

>BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  151 bits (367), Expect = 5e-36
 Identities = 136/505 (26%), Positives = 219/505 (43%), Gaps = 46/505 (9%)

Query: 34  TESGWVCGRSRRAEASTLYAS-FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           T  GW+ G+      S +  + F GVP+A  P+G LRF   QPA PW +  +AT    +C
Sbjct: 35  TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94

Query: 93  YQTD---VLYGSLMKPH----GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXX 145
            Q     +L   ++K H    G++E C+Y NI+ P +A     +T +K  LP+LV+    
Sbjct: 95  LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGG 147

Query: 146 XXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWV 205
                       G       +V+V+   YRL  FGFF+      PGN   +D V  L WV
Sbjct: 148 AFKTGSASI-FDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWV 206

Query: 206 KRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXX 265
           ++N   FGG+P +V                     +GL  +AI+ SG             
Sbjct: 207 QKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYE 266

Query: 266 XXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG 325
                +++    G N+++ + +   L   P ++L     + + Q    +F  VV+     
Sbjct: 267 KSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD----- 315

Query: 326 ITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL 385
                  +P  L+ Q   K IP IIG  N EC       E  +I+S  N++ A+ +  N+
Sbjct: 316 -GAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNI 374

Query: 386 LYSSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFL 445
           L+   P+ + LV+N+      + +   +  +++  D ++  PAL  A     AG APV+ 
Sbjct: 375 LH-IPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAG-APVYF 432

Query: 446 YQFSYDGYSVFKQAFHLHFNGAGHADDLTYV-----LK--VNSASGTSSSQK--ADDEMK 496
           Y+F +     F+      F  A HAD++ +V     LK  +    G +  +K  +   MK
Sbjct: 433 YEFRHRP-QCFEDT-KPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMK 490

Query: 497 YWMTTFVTNFMRCSAPMCDETTAWP 521
           YW T     F R   P  ++ + WP
Sbjct: 491 YWAT-----FARTGNPNGNDLSLWP 510


>BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  151 bits (367), Expect = 5e-36
 Identities = 136/505 (26%), Positives = 219/505 (43%), Gaps = 46/505 (9%)

Query: 34  TESGWVCGRSRRAEASTLYAS-FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           T  GW+ G+      S +  + F GVP+A  P+G LRF   QPA PW +  +AT    +C
Sbjct: 35  TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94

Query: 93  YQTD---VLYGSLMKPH----GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXX 145
            Q     +L   ++K H    G++E C+Y NI+ P +A     +T +K  LP+LV+    
Sbjct: 95  LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGG 147

Query: 146 XXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWV 205
                       G       +V+V+   YRL  FGFF+      PGN   +D V  L WV
Sbjct: 148 AFKTGSASI-FDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWV 206

Query: 206 KRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXX 265
           ++N   FGG+P +V                     +GL  +AI+ SG             
Sbjct: 207 QKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYE 266

Query: 266 XXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG 325
                +++    G N+++ + +   L   P ++L     + + Q    +F  VV+     
Sbjct: 267 KSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD----- 315

Query: 326 ITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL 385
                  +P  L+ Q   K IP IIG  N EC       E  +I+S  N++ A+ +  N+
Sbjct: 316 -GAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNI 374

Query: 386 LYSSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFL 445
           L+   P+ + LV+N+      + +   +  +++  D ++  PAL  A     AG APV+ 
Sbjct: 375 LH-IPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAG-APVYF 432

Query: 446 YQFSYDGYSVFKQAFHLHFNGAGHADDLTYV-----LK--VNSASGTSSSQK--ADDEMK 496
           Y+F +     F+      F  A HAD++ +V     LK  +    G +  +K  +   MK
Sbjct: 433 YEFRHRP-QCFEDT-KPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMK 490

Query: 497 YWMTTFVTNFMRCSAPMCDETTAWP 521
           YW T     F R   P  ++ + WP
Sbjct: 491 YWAT-----FARTGNPNGNDLSLWP 510


>AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5
           protein.
          Length = 575

 Score =  151 bits (367), Expect = 5e-36
 Identities = 136/505 (26%), Positives = 219/505 (43%), Gaps = 46/505 (9%)

Query: 34  TESGWVCGRSRRAEASTLYAS-FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           T  GW+ G+      S +  + F GVP+A  P+G LRF   QPA PW +  +AT    +C
Sbjct: 35  TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94

Query: 93  YQTD---VLYGSLMKPH----GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXX 145
            Q     +L   ++K H    G++E C+Y NI+ P +A     +T +K  LP+LV+    
Sbjct: 95  LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGG 147

Query: 146 XXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWV 205
                       G       +V+V+   YRL  FGFF+      PGN   +D V  L WV
Sbjct: 148 AFKTGSASI-FDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWV 206

Query: 206 KRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXX 265
           ++N   FGG+P +V                     +GL  +AI+ SG             
Sbjct: 207 QKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYE 266

Query: 266 XXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG 325
                +++    G N+++ + +   L   P ++L     + + Q    +F  VV+     
Sbjct: 267 KSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD----- 315

Query: 326 ITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL 385
                  +P  L+ Q   K IP IIG  N EC       E  +I+S  N++ A+ +  N+
Sbjct: 316 -GAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNI 374

Query: 386 LYSSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFL 445
           L+   P+ + LV+N+      + +   +  +++  D ++  PAL  A     AG APV+ 
Sbjct: 375 LH-IPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAG-APVYF 432

Query: 446 YQFSYDGYSVFKQAFHLHFNGAGHADDLTYV-----LK--VNSASGTSSSQK--ADDEMK 496
           Y+F +     F+      F  A HAD++ +V     LK  +    G +  +K  +   MK
Sbjct: 433 YEFRHRP-QCFEDT-KPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMK 490

Query: 497 YWMTTFVTNFMRCSAPMCDETTAWP 521
           YW T     F R   P  ++ + WP
Sbjct: 491 YWAT-----FARTGNPNGNDLSLWP 510


>BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7
           protein.
          Length = 525

 Score =  132 bits (320), Expect = 2e-30
 Identities = 107/404 (26%), Positives = 176/404 (43%), Gaps = 29/404 (7%)

Query: 34  TESGWVCGRSRRAEASTLYAS-FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           T  GW+ G+      S +  + F GVP+A  P+G LRF   QPA PW +  +AT    +C
Sbjct: 35  TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94

Query: 93  YQTD---VLYGSLMKPH----GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXX 145
            Q     +L   ++K H    G++E C+Y NI+ P +A     +T +K  LP+LV+    
Sbjct: 95  LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGG 147

Query: 146 XXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWV 205
                       G       +V+V+   YRL  FGFF+      PGN   +D V  L WV
Sbjct: 148 AFKTGSASI-FDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWV 206

Query: 206 KRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXX 265
           ++N   FGG+P +V                     +GL  +AI+ SG             
Sbjct: 207 QKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYE 266

Query: 266 XXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG 325
                +++    G N+++ + +   L   P ++L     + + Q    +F  VV+     
Sbjct: 267 KSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD----- 315

Query: 326 ITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL 385
                  +P  L+ Q   K IP IIG  N EC       E  +I+S  N++ A+ +  N+
Sbjct: 316 -GAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNI 374

Query: 386 LYSSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPAL 429
           L+   P+ + LV+N+      + +   +  +++  D ++  PAL
Sbjct: 375 LH-IPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPAL 417


>AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 525

 Score =  132 bits (320), Expect = 2e-30
 Identities = 107/404 (26%), Positives = 176/404 (43%), Gaps = 29/404 (7%)

Query: 34  TESGWVCGRSRRAEASTLYAS-FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           T  GW+ G+      S +  + F GVP+A  P+G LRF   QPA PW +  +AT    +C
Sbjct: 35  TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94

Query: 93  YQTD---VLYGSLMKPH----GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXX 145
            Q     +L   ++K H    G++E C+Y NI+ P +A     +T +K  LP+LV+    
Sbjct: 95  LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGG 147

Query: 146 XXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWV 205
                       G       +V+V+   YRL  FGFF+      PGN   +D V  L WV
Sbjct: 148 AFKTGSASI-FDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWV 206

Query: 206 KRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXX 265
           ++N   FGG+P +V                     +GL  +AI+ SG             
Sbjct: 207 QKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYE 266

Query: 266 XXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG 325
                +++    G N+++ + +   L   P ++L     + + Q    +F  VV+     
Sbjct: 267 KSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD----- 315

Query: 326 ITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL 385
                  +P  L+ Q   K IP IIG  N EC       E  +I+S  N++ A+ +  N+
Sbjct: 316 -GAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNI 374

Query: 386 LYSSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPAL 429
           L+   P+ + LV+N+      + +   +  +++  D ++  PAL
Sbjct: 375 LH-IPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPAL 417


>AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase
           hBr2 protein.
          Length = 565

 Score =  132 bits (318), Expect = 4e-30
 Identities = 142/542 (26%), Positives = 213/542 (39%), Gaps = 50/542 (9%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F GVP+AK P+G LRF   Q AEPW    + T   
Sbjct: 25  VVDTVQGKVLGKYVSLEGFAQPVAVFLGVPFAKPPLGPLRFAPPQAAEPWNFVKNTTSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D + G ++           P   +E C+Y NI+ P        +      LP++
Sbjct: 85  PMCSQ-DAVGGQVLSELFTNRKDNIPLKFSEDCLYLNIYTP-------ADLTKNSRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D +
Sbjct: 137 VWIHGGGLVVGGASTY-DGLALSAHENVVVVTIQYRLGIWGFFSTGDEHGRGNWGHLDQL 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N   FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQENIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTAAL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRIL----IDQIG-LTT 314
                        +F+  G  ST    +   L     ++L E +  L    +D +G    
Sbjct: 256 VKKDMKDTAQQIAVFA--GCKSTTSAVLVHCLRQKTEDELLEVSLKLKFFTLDLLGDPRE 313

Query: 315 FFPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDI-VSKI 373
            +P + T   G+  +L + P  ++ + +   +P IIG    E            +   K+
Sbjct: 314 SYPFLPTVVDGV--LLPKMPQEILAEKKFNSVPYIIGINKQEFGWLLPMMMGYPLSEDKL 371

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI----SQRYFNGSVD----LEGFINMCTDSYYK 425
           ++  A    S+LL+ S P  IA +  ++    S++Y  G+ D       F++M  D  + 
Sbjct: 372 DQKTA----SSLLWKSYP--IANIPEELTPLASEKYLGGTDDPVKKKALFLDMLGDVVFG 425

Query: 426 YPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGT 485
            P++ +A     AG AP ++Y+F Y  +  F            H D+L  V       G 
Sbjct: 426 VPSVTVARHHRDAG-APTYMYEFQY--HPSFSSDMKPQTVVGDHGDELFSVFGAPFLKGG 482

Query: 486 SSSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLT 545
           +S ++    +   M     NF R   PM    ++WP    +E  Y  I  P    Q   +
Sbjct: 483 ASEEEI--RLSKMMMKLWANFARSGNPMGKGCSSWPAYDQKE-GYLQIGIPTQPAQKLKS 539

Query: 546 KE 547
           KE
Sbjct: 540 KE 541


>AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 571

 Score =  127 bits (307), Expect = 9e-29
 Identities = 120/522 (22%), Positives = 209/522 (40%), Gaps = 42/522 (8%)

Query: 31  VAQTESGWVCGRSRRAEAST-----LYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDA 85
           VAQ E     GR R  +        L   F G+P+A+ P+G  RF    PA+PW    DA
Sbjct: 31  VAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDA 90

Query: 86  TEEGPVCYQ-TDVLYGSLMKPHG------MNEACIYANIHVPLYALPAAGETPTKPGLPI 138
           +   P+C Q  + +  S    +G      ++E C+  N++ P        E P   G P+
Sbjct: 91  STAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSP-------AEVPAGSGRPV 143

Query: 139 LVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDM 198
           +V++H              G       +VVV+T  YRL   GFFS      PGN G  D+
Sbjct: 144 MVWVHGGALITGAATSY-DGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDV 202

Query: 199 VTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXX 258
           V  LRWV+ N   FGG+ + V                      GL  RAI  SG      
Sbjct: 203 VAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGV--ITT 260

Query: 259 XXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPV 318
                     + + + + L  +S++P E+ + L      +  E   +++ +    T +P+
Sbjct: 261 PGIIDSHPWPLAQKIANTLACSSSSPAEMVQCL------QQKEGEELVLSKKLKNTIYPL 314

Query: 319 VETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE-CHMFQRRFEQIDIVSKINENP 377
                    T+  + P  L+++     +P ++G  N E   +  R +  +D + +++   
Sbjct: 315 TVD-----GTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSRED 369

Query: 378 AILVPSNLLYS--STPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKR 435
            + + + +L S    PE +  V ++      +     + F     D +   P ++ +   
Sbjct: 370 MLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYL 429

Query: 436 STAGDAPVFLYQFSY--DGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
             +G +PVF Y+F +    ++  K A+    +GA  A        ++ +S  +  +  ++
Sbjct: 430 RDSG-SPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEE 488

Query: 494 EMKYWMTTFV--TNFMRCSAPMCDETTAWPPVTPRELQYQDI 533
           E +  +T     T+F R   P       WP     E QY +I
Sbjct: 489 EKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAE-QYLEI 529


>BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.
          Length = 568

 Score =  126 bits (305), Expect = 2e-28
 Identities = 123/521 (23%), Positives = 205/521 (39%), Gaps = 43/521 (8%)

Query: 31  VAQTESGWVCGRSRRAEAST-----LYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDA 85
           VAQ E     GR R  +        L   F G+P+A+ P+G  RF    PA+PW    DA
Sbjct: 31  VAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDA 90

Query: 86  TEEGPVCYQ-TDVLYGSLMKPHG------MNEACIYANIHVPLYALPAAGETPTKPGLPI 138
           +   P+C Q  + +  S    +G      ++E C+  N++ P        E P   G P+
Sbjct: 91  STAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSP-------AEVPAGSGRPV 143

Query: 139 LVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDM 198
           +V++H              G       +VVV+T  YRL   GFFS      PGN G  D+
Sbjct: 144 MVWVHGGALITGAATSY-DGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDV 202

Query: 199 VTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXX 258
           V  LRWV+ N   FGG+ + V                      GL  RAI  SG      
Sbjct: 203 VAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGV--ITT 260

Query: 259 XXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPV 318
                     + + + + L  +S++P E+ + L      +  E   +++ +    T +P+
Sbjct: 261 PGIIDSHPWPLAQKIANTLACSSSSPAEMVQCL------QQKEGEELVLSKKLKNTIYPL 314

Query: 319 VETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE-CHMFQRRFEQIDIVSKINENP 377
                    T+  + P  L+++     +P ++G  N E   +  R +  +D + +++   
Sbjct: 315 TVD-----GTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSRED 369

Query: 378 AILVPSNLLYS--STPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKR 435
            + + + +L S    PE +  V ++      +     + F     D +   P ++ +   
Sbjct: 370 MLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYL 429

Query: 436 STAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADDEM 495
             +G +PVF Y+F +   S  K      +  A H  +  +V         SS  +A +E 
Sbjct: 430 RDSG-SPVFFYEFQHRPSSFAK--IKPAWVKADHGAEGAFVFGGPFLMDESSRLEATEEE 486

Query: 496 KYWMTTFV---TNFMRCSAPMCDETTAWPPVTPRELQYQDI 533
           K    T +   T+F R   P       WP     E QY +I
Sbjct: 487 KQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAE-QYLEI 526


>AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase
           hBr3 protein.
          Length = 567

 Score =  126 bits (303), Expect = 3e-28
 Identities = 132/514 (25%), Positives = 204/514 (39%), Gaps = 44/514 (8%)

Query: 31  VAQTESGWVCGRSRRAEASTL-YASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  T   A F GVP+AK P+G LRF   QPAEPW+   + T   
Sbjct: 25  VVNTVKGKVLGKYVNLEGFTQPVAFFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYP 84

Query: 90  PVCYQTDVLYGSLMK---------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILV 140
           P+C Q  V +  L +         P   +E C+Y NI+ P        +      LP++V
Sbjct: 85  PMCSQDAVGWQVLSELFTNRKENIPLQFSEDCLYLNIYTP-------ADLTKNSRLPVMV 137

Query: 141 FIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           +IH              G       NVVV+T  YRL  +GFFS       GN G  D V 
Sbjct: 138 WIHGGGLVVGGASTY-DGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV+ N   FGGNP +V                     + L  RAI  S +G      
Sbjct: 197 ALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAI--SESGVSLTAA 254

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEA----NRILIDQIG-LTTF 315
                   I  L+ ++ G  +T    +   L     ++L E     N   +D +G     
Sbjct: 255 LITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKES 314

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIV-SKIN 374
           +P + T   G+  +L + P  ++ +     +P I+G    E            +   K++
Sbjct: 315 YPFLPTVIDGV--VLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPLAEGKLD 372

Query: 375 ENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKYP 427
           +  A    ++LL+ S P T+ +  N I   +++Y  G+ DL    + F ++  D  +  P
Sbjct: 373 QKTA----NSLLWKSYP-TLKISENMIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVP 427

Query: 428 ALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSS 487
           ++ ++     AG A  ++Y+F Y    V +        G  H D++  V    S      
Sbjct: 428 SVIVSRSHRDAG-ASTYMYEFEYRPSFVSRHEDPKAVIG-DHGDEIFSVF--GSPFLKDG 483

Query: 488 SQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWP 521
           + + +  +   +  F  NF R   P       WP
Sbjct: 484 ASEEETNLSKMVMKFWANFARNGNPNGGGLPHWP 517


>Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.
          Length = 559

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 33  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 92

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 93  AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 145

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 146 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 203

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 204 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 263

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 264 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 310

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 311 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 368

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 369 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 425

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 426 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 481

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 482 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 517


>U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.
          Length = 550

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 24  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 83

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 84  AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 136

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 137 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 194

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 195 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 254

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 255 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 301

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 302 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 359

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 360 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 416

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 417 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 472

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 473 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 508


>D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precursor
           protein.
          Length = 559

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 33  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 92

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 93  AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 145

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 146 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 203

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 204 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 263

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 264 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 310

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 311 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 368

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 369 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 425

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 426 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 481

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 482 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 517


>BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 97  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 157 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 209

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 210 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 328 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 374

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 375 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 432

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 433 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 489

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 490 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 545

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 546 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 581


>AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 97  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 157 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 209

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 210 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 328 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 374

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 375 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 432

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 433 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 489

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 490 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 545

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 546 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 581


>AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isoform
           1 variant protein.
          Length = 582

 Score =  122 bits (294), Expect = 3e-27
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 49/517 (9%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 56  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 115

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 116 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 168

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 169 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 226

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 227 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 286

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 287 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 333

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 334 PGVVDGV--FLPRHPKELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 391

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 392 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 448

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADD 493
            + +   APV+ Y+F +   S  K     H   A H D+L +V +           + ++
Sbjct: 449 FQCSR--APVYFYEFQHQP-SWLKNIRPPHMK-ADHGDELPFVFRSFFGGNYIKFTEEEE 504

Query: 494 EMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQY 530
           ++   M  +  NF R   P  +    W P+  +E QY
Sbjct: 505 QLSRKMMKYWANFARNGNPNGEGLPHW-PLFDQEEQY 540


>BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 566

 Score =  120 bits (288), Expect = 2e-26
 Identities = 136/550 (24%), Positives = 212/550 (38%), Gaps = 45/550 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDI-VSKIN 374
            P++ T   G+  +L + P  L  +     +P ++G    E            +   +++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLD 373

Query: 375 ENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKYP 427
           +  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  P
Sbjct: 374 QKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 428

Query: 428 ALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSS 487
           ++ +A     AG AP ++Y+F Y     F            H D+L  V         +S
Sbjct: 429 SVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGAS 485

Query: 488 SQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTKE 547
            ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    KE
Sbjct: 486 EEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDKE 542

Query: 548 QLEMKNFFDK 557
                N F K
Sbjct: 543 VAFWTNLFAK 552


>S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholesterol
           acyltransferase protein.
          Length = 568

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 26  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 85

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 86  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 137

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 138 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 196

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 197 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 256

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 257 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 316

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 317 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 374

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 375 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 429

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 430 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 486

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 487 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 543

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 544 EVAFWTNLFAK 554


>M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  118 bits (285), Expect = 4e-26
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.
          Length = 566

 Score =  118 bits (284), Expect = 6e-26
 Identities = 135/550 (24%), Positives = 211/550 (38%), Gaps = 45/550 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+ K P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDI-VSKIN 374
            P++ T   G+  +L + P  L  +     +P ++G    E            +   +++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLD 373

Query: 375 ENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKYP 427
           +  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  P
Sbjct: 374 QKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 428

Query: 428 ALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSS 487
           ++ +A     AG AP ++Y+F Y     F            H D+L  V         +S
Sbjct: 429 SVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGAS 485

Query: 488 SQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTKE 547
            ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    KE
Sbjct: 486 EEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAGQKLKDKE 542

Query: 548 QLEMKNFFDK 557
                N F K
Sbjct: 543 VAFWTNLFAK 552


>M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  118 bits (283), Expect = 7e-26
 Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 27/339 (7%)

Query: 29  NVVAQTESGWVCGRSRRAEASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEE 88
           +++  T++G V G +      T+ A F G+PYA+ P+G LRFK+ Q    W+D  +AT+ 
Sbjct: 31  DIIIATKNGKVRGMNLTVFGGTVTA-FLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89

Query: 89  GPVCYQT-----DVLYGSLM-KPH-GMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
              C Q         +GS M  P+  ++E C+Y N+ +P          P      +L++
Sbjct: 90  ANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP---------APKPKNATVLIW 140

Query: 142 IHXXXXXXXXXXXXLYGPEYLV-TRNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMV 199
           I+            +Y  ++L     V+V++ NYR+   GF +L   P+ PGN GL D  
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             L+WV++N  AFGGNP +V                    +  L +RAIL SG+      
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK--LNEANRILIDQIGLTTFFP 317
                        L  + G +  N  EI + L     ++  LNEA  +         F P
Sbjct: 261 VTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGP 320

Query: 318 VVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE 356
            V+         L + P+IL++ G+ K   +++G    E
Sbjct: 321 TVD------GDFLTDMPDILLELGQFKKTQILVGVNKDE 353


>M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  118 bits (283), Expect = 7e-26
 Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 27/339 (7%)

Query: 29  NVVAQTESGWVCGRSRRAEASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEE 88
           +++  T++G V G +      T+ A F G+PYA+ P+G LRFK+ Q    W+D  +AT+ 
Sbjct: 31  DIIIATKNGKVRGMNLTVFGGTVTA-FLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89

Query: 89  GPVCYQT-----DVLYGSLM-KPH-GMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
              C Q         +GS M  P+  ++E C+Y N+ +P          P      +L++
Sbjct: 90  ANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP---------APKPKNATVLIW 140

Query: 142 IHXXXXXXXXXXXXLYGPEYLV-TRNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMV 199
           I+            +Y  ++L     V+V++ NYR+   GF +L   P+ PGN GL D  
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             L+WV++N  AFGGNP +V                    +  L +RAIL SG+      
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK--LNEANRILIDQIGLTTFFP 317
                        L  + G +  N  EI + L     ++  LNEA  +         F P
Sbjct: 261 VTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGP 320

Query: 318 VVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE 356
            V+         L + P+IL++ G+ K   +++G    E
Sbjct: 321 TVD------GDFLTDMPDILLELGQFKKTQILVGVNKDE 353


>M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  118 bits (283), Expect = 7e-26
 Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 27/339 (7%)

Query: 29  NVVAQTESGWVCGRSRRAEASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEE 88
           +++  T++G V G +      T+ A F G+PYA+ P+G LRFK+ Q    W+D  +AT+ 
Sbjct: 31  DIIIATKNGKVRGMNLTVFGGTVTA-FLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89

Query: 89  GPVCYQT-----DVLYGSLM-KPH-GMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
              C Q         +GS M  P+  ++E C+Y N+ +P          P      +L++
Sbjct: 90  ANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP---------APKPKNATVLIW 140

Query: 142 IHXXXXXXXXXXXXLYGPEYLV-TRNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMV 199
           I+            +Y  ++L     V+V++ NYR+   GF +L   P+ PGN GL D  
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             L+WV++N  AFGGNP +V                    +  L +RAIL SG+      
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK--LNEANRILIDQIGLTTFFP 317
                        L  + G +  N  EI + L     ++  LNEA  +         F P
Sbjct: 261 VTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGP 320

Query: 318 VVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE 356
            V+         L + P+IL++ G+ K   +++G    E
Sbjct: 321 TVD------GDFLTDMPDILLELGQFKKTQILVGVNKDE 353


>BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  118 bits (283), Expect = 7e-26
 Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 27/339 (7%)

Query: 29  NVVAQTESGWVCGRSRRAEASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEE 88
           +++  T++G V G +      T+ A F G+PYA+ P+G LRFK+ Q    W+D  +AT+ 
Sbjct: 31  DIIIATKNGKVRGMNLTVFGGTVTA-FLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89

Query: 89  GPVCYQT-----DVLYGSLM-KPH-GMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
              C Q         +GS M  P+  ++E C+Y N+ +P          P      +L++
Sbjct: 90  ANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP---------APKPKNATVLIW 140

Query: 142 IHXXXXXXXXXXXXLYGPEYLV-TRNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMV 199
           I+            +Y  ++L     V+V++ NYR+   GF +L   P+ PGN GL D  
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             L+WV++N  AFGGNP +V                    +  L +RAIL SG+      
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK--LNEANRILIDQIGLTTFFP 317
                        L  + G +  N  EI + L     ++  LNEA  +         F P
Sbjct: 261 VTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGP 320

Query: 318 VVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE 356
            V+         L + P+IL++ G+ K   +++G    E
Sbjct: 321 TVD------GDFLTDMPDILLELGQFKKTQILVGVNKDE 353


>L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.
          Length = 568

 Score =  117 bits (281), Expect = 1e-25
 Identities = 135/551 (24%), Positives = 213/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+ K P+G LRF   QPAEPW+   +AT   
Sbjct: 26  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYP 85

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 86  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 137

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 138 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 196

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 197 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 256

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 257 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 316

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 317 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 374

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 375 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 429

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 430 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 486

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 487 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAGQKLKDK 543

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 544 EVAFWTNLFAK 554


>BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.
          Length = 823

 Score =  115 bits (277), Expect = 4e-25
 Identities = 128/495 (25%), Positives = 201/495 (40%), Gaps = 59/495 (11%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--DVLYGSLMKP------- 105
           F GVPYA  P GE RF+  +P  PW+D  +AT+  PVC Q   D     +M P       
Sbjct: 80  FLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNL 139

Query: 106 -------HGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
                     +E C+Y NI+VP          P     P++V+IH            LY 
Sbjct: 140 DVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPK----PVMVYIHGGSYMEGTGN--LYD 193

Query: 159 PEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPD 217
              L +  NV+VIT NYRL   GF S       GN GL D++  LRW   N   FGG+P 
Sbjct: 194 GSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPL 253

Query: 218 NVXXXXX---------XXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXX 268
            +                            +T+GL  RAI  SG                
Sbjct: 254 RITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYA 313

Query: 269 INKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITT 328
             ++L + +G N ++  E+ E L   P ++L + + I   +  +  F PV++        
Sbjct: 314 --RMLATKVGCNVSDTVELVECLQKKPYKELVDQD-IQPARYHI-AFGPVID------GD 363

Query: 329 ILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAILVPSNLLY 387
           ++ +DP IL++QG   +  +++G    E   F +   +  D +S  + + A+    + LY
Sbjct: 364 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLY 423

Query: 388 SSTP------ETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDA 441
                     ETI  +    + R+ N     +  + + TD  +  PA+  A+  S  G +
Sbjct: 424 GYPEGKDVLRETIKFMYTDWADRH-NPETRRKTLLALFTDHQWVAPAVATADLHSNFG-S 481

Query: 442 PVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKY 497
           P + Y F +   +    A    +  A H D++ YVL +     T     +  K D  +  
Sbjct: 482 PTYFYAFYHHCQTDQVPA----WADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSA 537

Query: 498 WMTTFVTNFMRCSAP 512
            + T+ TNF +   P
Sbjct: 538 VVMTYWTNFAKTGDP 552


>AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.
          Length = 826

 Score =  115 bits (277), Expect = 4e-25
 Identities = 128/495 (25%), Positives = 201/495 (40%), Gaps = 59/495 (11%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--DVLYGSLMKP------- 105
           F GVPYA  P GE RF+  +P  PW+D  +AT+  PVC Q   D     +M P       
Sbjct: 83  FLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNL 142

Query: 106 -------HGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
                     +E C+Y NI+VP          P     P++V+IH            LY 
Sbjct: 143 DVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPK----PVMVYIHGGSYMEGTGN--LYD 196

Query: 159 PEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPD 217
              L +  NV+VIT NYRL   GF S       GN GL D++  LRW   N   FGG+P 
Sbjct: 197 GSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPL 256

Query: 218 NVXXXXX---------XXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXX 268
            +                            +T+GL  RAI  SG                
Sbjct: 257 RITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYA 316

Query: 269 INKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITT 328
             ++L + +G N ++  E+ E L   P ++L + + I   +  +  F PV++        
Sbjct: 317 --RMLATKVGCNVSDTVELVECLQKKPYKELVDQD-IQPARYHI-AFGPVID------GD 366

Query: 329 ILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAILVPSNLLY 387
           ++ +DP IL++QG   +  +++G    E   F +   +  D +S  + + A+    + LY
Sbjct: 367 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLY 426

Query: 388 SSTP------ETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDA 441
                     ETI  +    + R+ N     +  + + TD  +  PA+  A+  S  G +
Sbjct: 427 GYPEGKDVLRETIKFMYTDWADRH-NPETRRKTLLALFTDHQWVAPAVATADLHSNFG-S 484

Query: 442 PVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKY 497
           P + Y F +   +    A    +  A H D++ YVL +     T     +  K D  +  
Sbjct: 485 PTYFYAFYHHCQTDQVPA----WADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSA 540

Query: 498 WMTTFVTNFMRCSAP 512
            + T+ TNF +   P
Sbjct: 541 VVMTYWTNFAKTGDP 555


>M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase
           protein.
          Length = 614

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase,
           isoform E4-E5 precursor protein.
          Length = 617

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Yt
           blood group) protein.
          Length = 617

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.
          Length = 546

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (YT
           blood group) protein.
          Length = 617

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase
           isoform E4-E6 precursor variant protein.
          Length = 614

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related
           acetylcholinesterase protein.
          Length = 526

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.
          Length = 617

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.
          Length = 614

 Score =  115 bits (276), Expect = 5e-25
 Identities = 71/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P+LV+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.
          Length = 640

 Score =  114 bits (274), Expect = 9e-25
 Identities = 70/210 (33%), Positives = 105/210 (50%), Gaps = 17/210 (8%)

Query: 53  ASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQ-TDVLY----GSLM-KPH 106
           ++F G+P+A+ P+G  RF   +P +PW+  +DAT    VCYQ  D LY    G+ M  P+
Sbjct: 61  SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 120

Query: 107 G-MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLV-T 164
             ++E C+Y N+  P          PT P  P++V+I+            +Y   +LV  
Sbjct: 121 RELSEDCLYLNVWTPY-------PRPTSP-TPVIVWIYGGGFYSGASSLDVYDGRFLVQA 172

Query: 165 RNVVVITFNYRLNFFGFFSLD-TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXX 223
              V+++ NYR+  FGF +L  + + PGN GL D    L+WV+ N  AFGG+P +V    
Sbjct: 173 ERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFG 232

Query: 224 XXXXXXXXXXXXXXKATEGLVSRAILMSGA 253
                           + GL  RA+L SGA
Sbjct: 233 ESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262


>BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.
          Length = 454

 Score =  114 bits (274), Expect = 9e-25
 Identities = 84/313 (26%), Positives = 131/313 (41%), Gaps = 21/313 (6%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQTD-----VLYGSLMKPHG-- 107
           F GVP+++ P+G LRF   +P EPW    DAT   P C Q        +Y S  + +   
Sbjct: 14  FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWL 73

Query: 108 -MNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRN 166
             +E C+Y N++ P  A       P  P LP++V+                G +      
Sbjct: 74  RFSEDCLYLNVYAPARA-------PGDPQLPVMVWFPGGAFIVGAASSY-EGSDLAAREK 125

Query: 167 VVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXX 226
           VV++   +RL  FGF S D     GN GL D +  LRWV+ N  AFGG+P NV       
Sbjct: 126 VVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSA 185

Query: 227 XXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDE 286
                          GL  RAI  S +G              + K +  + G N  +   
Sbjct: 186 GAMSISGLMMSPLASGLFHRAI--SQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQI 243

Query: 287 IHEKLVAMPVEK-LNEANRILIDQIGLTTF-FPVVETPHPGIT-TILDEDPNILVQQGRG 343
           +   L A+   K +  +N++   Q+        ++ +  P +   ++ +DP +L+ QG+ 
Sbjct: 244 LVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKV 303

Query: 344 KDIPLIIGFTNSE 356
             +P ++G  N E
Sbjct: 304 SSVPYLLGVNNLE 316


>AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester
           hydrolase protein.
          Length = 567

 Score =  113 bits (273), Expect = 1e-24
 Identities = 134/551 (24%), Positives = 213/551 (38%), Gaps = 46/551 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LR    QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRSTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C + D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTR-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXX 259
             LRWV+ N  +FGGNP +V                     + L  RAI  SG       
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 255

Query: 260 XXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPVEKLNEANRILIDQIG-LTTF 315
                      ++  +     +T+   +H   +K     +E   +   + +D  G     
Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315

Query: 316 FPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKI 373
            P++ T   G+  +L + P  L  +     +P ++G    E   +   +     +   ++
Sbjct: 316 QPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 374 NENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVDL----EGFINMCTDSYYKY 426
           ++  A+    +LL+ S P  + +    I   +++Y  G+ D     + F+++  D  +  
Sbjct: 374 DQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV 428

Query: 427 PALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS 486
           P++ +A     AG AP ++Y+F Y     F            H D+L  V         +
Sbjct: 429 PSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGA 485

Query: 487 SSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRELQYQDIITPNLCHQTSLTK 546
           S ++    +   +  F  NF R   P  +    WP    +E  Y  I       Q    K
Sbjct: 486 SEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE-GYLQIGANTQAAQKLKDK 542

Query: 547 EQLEMKNFFDK 557
           E     N F K
Sbjct: 543 EVAFWTNLFAK 553


>BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  111 bits (268), Expect = 5e-24
 Identities = 121/487 (24%), Positives = 192/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +    WT   +AT+   VC Q         D+L        
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP+       E  +K   P++V+IH            + G
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME--DDIHEQNSKK--PVMVYIHGGSYMEGTGNM-IDG 187

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 248 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 305

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 306 CNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 357

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 358 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 415

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 416 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 473

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 474 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 529

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 530 FAKTGDP 536


>BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  111 bits (268), Expect = 5e-24
 Identities = 121/487 (24%), Positives = 192/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +    WT   +AT+   VC Q         D+L        
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP+       E  +K   P++V+IH            + G
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME--DDIHEQNSKK--PVMVYIHGGSYMEGTGNM-IDG 187

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 248 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 305

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 306 CNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 357

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 358 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 415

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 416 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 473

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 474 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 529

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 530 FAKTGDP 536


>AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.
          Length = 816

 Score =  111 bits (268), Expect = 5e-24
 Identities = 121/487 (24%), Positives = 192/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +    WT   +AT+   VC Q         D+L        
Sbjct: 73  YLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSL 132

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP+       E  +K   P++V+IH            + G
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPME--DDIHEQNSKK--PVMVYIHGGSYMEGTGNM-IDG 187

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 248 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 305

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 306 CNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 357

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 358 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 415

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 416 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 473

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 474 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 529

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 530 FAKTGDP 536


>AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 469

 Score =  111 bits (267), Expect = 6e-24
 Identities = 108/424 (25%), Positives = 180/424 (42%), Gaps = 38/424 (8%)

Query: 107 GMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRN 166
           G++E C+Y NI+ P +A     +T +K  LP+LV+                G       +
Sbjct: 10  GVSEDCLYLNIYAPAHA-----DTGSK--LPVLVWFPGGAFKTGSASI-FDGSALAAYED 61

Query: 167 VVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXX 226
           V+V+   YRL  FGFF+      PGN   +D V  L WV++N   FGG+P +V       
Sbjct: 62  VLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESA 121

Query: 227 XXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDE 286
                         +GL  +AI+ SG                  +++    G N+++ + 
Sbjct: 122 GAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEA 181

Query: 287 IHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILVQQGRGKDI 346
           +   L   P ++L     + + Q    +F  VV+            +P  L+ Q   K I
Sbjct: 182 LLRCLRTKPSKEL-----LTLSQ-KTKSFTRVVD------GAFFPNEPLDLLSQKAFKAI 229

Query: 347 PLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNLLYSSTPETIALVSNQISQRYF 406
           P IIG  + EC       E  +I+S  N++ A+ +  N+L+   P+ + LV+N+      
Sbjct: 230 PSIIGVNSHECGFLLPMKEAPEILSGSNKSLALHLIQNILH-IPPQYLHLVANEYFHDKH 288

Query: 407 NGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNG 466
           + +   +  +++  D ++  PAL  A     AG APV+ Y+F +     F+      F  
Sbjct: 289 SLTEIRDSLLDLLGDVFFVVPALITARYHRDAG-APVYFYEFRHRP-QCFEDT-KPAFVK 345

Query: 467 AGHADDLTYV-----LK--VNSASGTSSSQK--ADDEMKYWMTTFVTNFMRCSAPMCDET 517
           A HAD++ +V     LK  +    G +  +K  +   MKYW T     F R   P  ++ 
Sbjct: 346 ADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWAT-----FARTGNPNGNDL 400

Query: 518 TAWP 521
           + WP
Sbjct: 401 SLWP 404


>AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase
           hBr1 protein.
          Length = 429

 Score =  111 bits (266), Expect = 8e-24
 Identities = 79/233 (33%), Positives = 102/233 (43%), Gaps = 20/233 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 25  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+C Q D   G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 85  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 136

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS       GN G  D V
Sbjct: 137 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQV 195

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
             LRWV+ N  +FGGNP +V                     + L  RAI  SG
Sbjct: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESG 248


>BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked
           protein.
          Length = 816

 Score =  110 bits (265), Expect = 1e-23
 Identities = 120/487 (24%), Positives = 190/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +P   WT   + T+   VC Q         D+L        
Sbjct: 73  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 132

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP        +   KP   ++V+IH            + G
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPTED-DIHDQNSKKP---VMVYIHGGSYMEGTGNM-IDG 187

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 248 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 305

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 306 CNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 357

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 358 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 415

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 416 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 473

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 474 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 529

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 530 FAKTGDP 536


>AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.
          Length = 816

 Score =  110 bits (265), Expect = 1e-23
 Identities = 120/487 (24%), Positives = 190/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +P   WT   + T+   VC Q         D+L        
Sbjct: 73  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 132

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP        +   KP   ++V+IH            + G
Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPTED-DIHDQNSKKP---VMVYIHGGSYMEGTGNM-IDG 187

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 248 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 305

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 306 CNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 357

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 358 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 415

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 416 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 473

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 474 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 529

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 530 FAKTGDP 536


>AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.
          Length = 817

 Score =  110 bits (265), Expect = 1e-23
 Identities = 120/487 (24%), Positives = 190/487 (39%), Gaps = 52/487 (10%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +P   WT   + T+   VC Q         D+L        
Sbjct: 74  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 133

Query: 100 GSLMK-PHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYG 158
            +LM      NE C+Y NI+VP        +   KP   ++V+IH            + G
Sbjct: 134 DTLMTYVQDQNEDCLYLNIYVPTED-DIHDQNSKKP---VMVYIHGGSYMEGTGNM-IDG 188

Query: 159 PEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDN 218
                  NV+VIT NYRL   GF S       GN GL D +  LRW++ N  AFGG+P  
Sbjct: 189 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 248

Query: 219 VXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILG 278
           V                    +EGL  +AI+ S  G                ++L   +G
Sbjct: 249 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAVNYQPAKYTRILADKVG 306

Query: 279 VNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILV 338
            N  +  ++ E L     ++L    + +        F PV++        ++ +DP IL+
Sbjct: 307 CNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFGPVID------GDVIPDDPQILM 358

Query: 339 QQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNL---LY------SS 389
           +QG   +  +++G    E   F      +D    +  N      SN    LY       +
Sbjct: 359 EQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDT 416

Query: 390 TPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFS 449
             ETI  +    + +  N     +  + + TD  +  PA+  A+  +  G +P + Y F 
Sbjct: 417 LRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAVATADLHAQYG-SPTYFYAFY 474

Query: 450 YDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKYWMTTFVTN 505
           +   S  K +    +  + H D++ YV  +     T     +  K D  +   + T+ TN
Sbjct: 475 HHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTN 530

Query: 506 FMRCSAP 512
           F +   P
Sbjct: 531 FAKTGDP 537


>BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.
          Length = 587

 Score =  109 bits (261), Expect = 3e-23
 Identities = 110/437 (25%), Positives = 172/437 (39%), Gaps = 46/437 (10%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 77  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 136

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 137 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 189

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 190 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 247

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 248 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 307

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 308 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 354

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 355 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 412

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 413 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 469

Query: 434 KRSTAGDAPVFLYQFSY 450
            + +   APV+ Y+F +
Sbjct: 470 FQCSR--APVYFYEFQH 484


>BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.
          Length = 586

 Score =  109 bits (261), Expect = 3e-23
 Identities = 110/437 (25%), Positives = 172/437 (39%), Gaps = 46/437 (10%)

Query: 31  VAQTESGWVCGRSRRAE-ASTLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           +  T +G V G     + A+    +F G+P+AK P+G LRF   +P E W+   D T   
Sbjct: 76  IRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 135

Query: 90  PVCYQ------TDVL--YGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVF 141
            +C Q      ++ L  +        M+E C+Y +I+ P ++   +        LP++V+
Sbjct: 136 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSN-------LPVMVW 188

Query: 142 IHXXXXXXXXXXXXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVT 200
           IH            LY    L    NVVV+   YRL   GFFS       GN G  D V 
Sbjct: 189 IHGGALVFGMAS--LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 246

Query: 201 LLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXX 260
            LRWV++N   FGGNPD V                    ++GL   AI+ SG        
Sbjct: 247 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 306

Query: 261 XXXXXXXXINKLLFSILGVNSTNPDEI-HEKLVAMPVEKLNEANRILIDQIGLTTFFPVV 319
                       + S +  N +  D++  E LV     K  E      + + +   F ++
Sbjct: 307 ASSAD-------VISTVVANLSACDQVDSEALVGCLRGKSKE------EILAINKPFKMI 353

Query: 320 ETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA- 378
                G+   L   P  L+     + +P I+G  N+E      +  +I    K  +  A 
Sbjct: 354 PGVVDGV--FLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREAS 411

Query: 379 -ILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLE----GFINMCTDSYYKYPALNLAE 433
              +   L     P T     + + + Y   + D +     F  M  DS +  PAL +A 
Sbjct: 412 QAALQKMLTLLMLPPTF---GDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 468

Query: 434 KRSTAGDAPVFLYQFSY 450
            + +   APV+ Y+F +
Sbjct: 469 FQCSR--APVYFYEFQH 483


>BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.
          Length = 518

 Score =  108 bits (259), Expect = 6e-23
 Identities = 111/447 (24%), Positives = 179/447 (40%), Gaps = 44/447 (9%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT-DVLYGSLMKP-------- 105
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q        +M P        
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 106 ------HGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGP 159
                    NE C+Y N++V     P   +       P++V+IH            + G 
Sbjct: 129 IVATYIQEPNEDCLYLNVYV-----PTEDDIRDSGAKPVMVYIH-GGSYMEGTGNMIDGS 182

Query: 160 EYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNV 219
                 NV+VIT NYR+   GF S       GN GL D +  LRWV  N   FGG+P  +
Sbjct: 183 ILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRI 242

Query: 220 XXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGV 279
                               +EGL  RAI+ SG+                  LL   +G 
Sbjct: 243 TVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS--ALSSWAVNYQPVKYTSLLADKVGC 300

Query: 280 NSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILVQ 339
           N  +  ++ + L     ++L E +  +        F PV++        ++ +DP IL++
Sbjct: 301 NVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFGPVID------GDVIPDDPEILME 352

Query: 340 QGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAILVPSNLLY------SSTPE 392
           QG   +  +++G    E   F +   +  D VS  + + ++    + LY       +  E
Sbjct: 353 QGEFLNYDVMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRE 412

Query: 393 TIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDG 452
           TI  +    + R  N     +  + + TD  +  P++  A+  +  G +P + Y F +  
Sbjct: 413 TIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSVVTADLHARYG-SPTYFYAFYHHC 470

Query: 453 YSVFKQAFHLHFNGAGHADDLTYVLKV 479
            S+ K A    ++ A H D++ YV  V
Sbjct: 471 QSLMKPA----WSDAAHGDEVPYVFGV 493


>BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.
          Length = 722

 Score =  105 bits (253), Expect = 3e-22
 Identities = 128/517 (24%), Positives = 202/517 (39%), Gaps = 41/517 (7%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINK 271
           FGG+P+N+                     +GL+ RA  +S +G                K
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRA--ISQSGVALSPWVIQKNPLFWAK 261

Query: 272 LLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTILD 331
            +   +G    +   + + L       L  A ++ +   GL   +P++   + G   ++D
Sbjct: 262 KVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPL--AGLE--YPMLH--YVGFVPVID 315

Query: 332 ED---PNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVPSNLLYS 388
            D    + +       DI  I G  N + H+F      ID+ +    N  +      L S
Sbjct: 316 GDFIPADPINLYANAADIDYIAGTNNMDGHIFA----SIDMPAINKGNKKVTEDFYKLVS 371

Query: 389 STPETIALVSNQISQRYFNGSVDLEG--------FINMCTDSYYKYPA-LNLAEKRSTAG 439
               T  L   + +   +  S   +          ++  TD  +  P  + LA+ R+ A 
Sbjct: 372 EFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAK 431

Query: 440 DAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADDEMKYWM 499
            A  + Y FS+      +   +  + GA HADD+ YV     A+ T   +  D  +   M
Sbjct: 432 SAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFGKPFATPT-GYRPQDRTVSKAM 486

Query: 500 TTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
             + TNF +   P   ++   T W P T     Y +I
Sbjct: 487 IAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 523


>AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-related
           protein protein.
          Length = 288

 Score =  105 bits (253), Expect = 3e-22
 Identities = 76/233 (32%), Positives = 100/233 (42%), Gaps = 19/233 (8%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 26  VVDTVHGKVLGKFISLEGFAQPVAVFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATLYP 85

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYALPAAGETPTKPGLPIL 139
           P+  Q     G L+           P  ++E C+Y NI+ P        +   K  LP++
Sbjct: 86  PMFTQDPRRGGQLISELFTNRKENIPLKLSEDCLYLNIYTP-------ADLTKKNRLPVM 138

Query: 140 VFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMV 199
           V+IH              G       NVVV+T  YRL  +GFFS      PGN G  D +
Sbjct: 139 VWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQL 197

Query: 200 TLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
             L WV+ N  +FGGNP +V                     + L  RAI  SG
Sbjct: 198 AALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESG 250


>AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.
          Length = 835

 Score =  103 bits (247), Expect = 2e-21
 Identities = 132/522 (25%), Positives = 196/522 (37%), Gaps = 57/522 (10%)

Query: 31  VAQTESGWVCGRSRRAEASTL--YASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEE 88
           V  T  G V G  R      L     F GVPYA  P+G  RF+  +    W    +AT  
Sbjct: 43  VVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTL 102

Query: 89  GPVCYQ---------------TDVLYGSLMKPHGMNEACIYANIHVPLYALPAAG----- 128
            P C Q               TD L  +       +E C+Y N++VP    P        
Sbjct: 103 PPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEA 162

Query: 129 -----ETPTK-PGL-PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGF 181
                +T  + PG  P+++F+H              G       NV+V T NYRL   GF
Sbjct: 163 TLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM-FDGSVLAAYGNVIVATLNYRLGVLGF 221

Query: 182 FSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATE 241
            S       GN GL D +  LRW+  N   FGG+P+ +                    +E
Sbjct: 222 LSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSE 281

Query: 242 GLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNE 301
           GL  +AI  S  G                +LL + +G +  +  E  E L   P  +L +
Sbjct: 282 GLFQKAIAQS--GTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVD 339

Query: 302 ANRILIDQIGLTTFFPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF- 360
            + +   +  +  F PVV+        ++ +DP IL+QQG   +  ++IG    E   F 
Sbjct: 340 QD-VQPARYHI-AFGPVVD------GDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFV 391

Query: 361 QRRFEQIDIVSKINENPAILVPSNLLYSSTP------ETIALVSNQISQRYFNGSVDLEG 414
           +   E  D VS    +  +    + LY          ETI  +    + R  NG +  + 
Sbjct: 392 EDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADR-DNGEMRRKT 450

Query: 415 FINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLT 474
            + + TD  +  PA+  A K      +PV+ Y F    Y   +      +  A H D+L 
Sbjct: 451 LLALFTDHQWVAPAVATA-KLHADYQSPVYFYTF----YHHCQAEGRPEWADAAHGDELP 505

Query: 475 YVLKVNSASGTS----SSQKADDEMKYWMTTFVTNFMRCSAP 512
           YV  V     T     +  K D  +   + T+ TNF +   P
Sbjct: 506 YVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 547


>AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 828

 Score =  103 bits (246), Expect = 2e-21
 Identities = 122/502 (24%), Positives = 197/502 (39%), Gaps = 64/502 (12%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT------------------D 96
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q                   D
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 97  VLYGSLMKPHGMNEACIYANIHVPLYALPAA---GETPT------------KPGLPILVF 141
           ++   + +P   NE C+Y N++VP      A   GE                   P++V+
Sbjct: 129 IVATYIQEP---NEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVY 185

Query: 142 IHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTL 201
           IH            + G       NV+VIT NYR+   GF S       GN GL D +  
Sbjct: 186 IHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQA 244

Query: 202 LRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXX 261
           LRWV  N   FGG+P  +                    +EGL  RAI+ SG+        
Sbjct: 245 LRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVN 304

Query: 262 XXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVET 321
                     LL   +G N  +  ++ + L     ++L E +  +        F PV++ 
Sbjct: 305 YQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFGPVIDG 360

Query: 322 PHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAIL 380
                  ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + + ++ 
Sbjct: 361 D------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVS 414

Query: 381 VPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEK 434
              + LY       +  ETI  +    + R  N     +  + + TD  +  P++  A+ 
Sbjct: 415 NFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 435 RSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQK 490
            +  G +P + Y F +   S+ K A    ++ A H D++ YV  V     T     +  K
Sbjct: 474 HARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGVPMVGPTDLFPCNFSK 528

Query: 491 ADDEMKYWMTTFVTNFMRCSAP 512
            D  +   + T+ TNF +   P
Sbjct: 529 NDVMLSAVVMTYWTNFAKTGDP 550


>BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.
          Length = 828

 Score =  102 bits (244), Expect = 4e-21
 Identities = 122/502 (24%), Positives = 197/502 (39%), Gaps = 64/502 (12%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT------------------D 96
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q                   D
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPYWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 97  VLYGSLMKPHGMNEACIYANIHVPLYALPAA---GETPT------------KPGLPILVF 141
           ++   + +P   NE C+Y N++VP      A   GE                   P++V+
Sbjct: 129 IVATYIQEP---NEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVY 185

Query: 142 IHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTL 201
           IH            + G       NV+VIT NYR+   GF S       GN GL D +  
Sbjct: 186 IHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQA 244

Query: 202 LRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXX 261
           LRWV  N   FGG+P  +                    +EGL  RAI+ SG+        
Sbjct: 245 LRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVN 304

Query: 262 XXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVET 321
                     LL   +G N  +  ++ + L     ++L E +  +        F PV++ 
Sbjct: 305 YQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFGPVIDG 360

Query: 322 PHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAIL 380
                  ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + + ++ 
Sbjct: 361 D------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVS 414

Query: 381 VPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEK 434
              + LY       +  ETI  +    + R  N     +  + + TD  +  P++  A+ 
Sbjct: 415 NFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 435 RSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQK 490
            +  G +P + Y F +   S+ K A    ++ A H D++ YV  V     T     +  K
Sbjct: 474 HARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGVPMVGPTDLFPCNFSK 528

Query: 491 ADDEMKYWMTTFVTNFMRCSAP 512
            D  +   + T+ TNF +   P
Sbjct: 529 NDVMLSAVVMTYWTNFAKTGDP 550


>AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HNL3
           protein.
          Length = 828

 Score =  102 bits (244), Expect = 4e-21
 Identities = 122/502 (24%), Positives = 197/502 (39%), Gaps = 64/502 (12%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT------------------D 96
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q                   D
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 97  VLYGSLMKPHGMNEACIYANIHVPLYALPAA---GETPT------------KPGLPILVF 141
           ++   + +P   NE C+Y N++VP      A   GE                   P++V+
Sbjct: 129 IVATYIQEP---NEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVY 185

Query: 142 IHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTL 201
           IH            + G       NV+VIT NYR+   GF S       GN GL D +  
Sbjct: 186 IHGGSYMEGTGNM-IDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQA 244

Query: 202 LRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXX 261
           LRWV  N   FGG+P  +                    +EGL  RAI+ SG+        
Sbjct: 245 LRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVN 304

Query: 262 XXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVET 321
                     LL   +G N  +  ++ + L     ++L E +  +        F PV++ 
Sbjct: 305 YQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFGPVIDG 360

Query: 322 PHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAIL 380
                  ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + + ++ 
Sbjct: 361 D------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVS 414

Query: 381 VPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEK 434
              + LY       +  ETI  +    + R  N     +  + + TD  +  P++  A+ 
Sbjct: 415 NFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSVVTADL 473

Query: 435 RSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQK 490
            +  G +P + Y F +   S+ K A    ++ A H D++ YV  V     T     +  K
Sbjct: 474 HARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGVPMVGPTDLFPCNFSK 528

Query: 491 ADDEMKYWMTTFVTNFMRCSAP 512
            D  +   + T+ TNF +   P
Sbjct: 529 NDVMLSAVVMTYWTNFAKTGDP 550


>BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.
          Length = 442

 Score =  101 bits (242), Expect = 7e-21
 Identities = 93/407 (22%), Positives = 158/407 (38%), Gaps = 23/407 (5%)

Query: 126 AAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLD 185
           A    P  P LP++V+                G +      VV++   +RL  FGF S D
Sbjct: 4   APARAPGDPQLPVMVWFPGGAFIVGAASSY-EGSDLAAREKVVLVFLQHRLGIFGFLSTD 62

Query: 186 TPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVS 245
                GN GL D +  LRWV+ N  AFGG+P NV                      GL  
Sbjct: 63  DSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFH 122

Query: 246 RAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK-LNEANR 304
           RAI  S +G              + K +  + G N  +   +   L A+   K +  +N+
Sbjct: 123 RAI--SQSGTALFRLFITRNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNK 180

Query: 305 ILIDQIGLTTF-FPVVETPHPGIT-TILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQR 362
           +   Q+        ++ +  P +   ++ +DP +L+ QG+   +P ++G  N E +    
Sbjct: 181 MRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP 240

Query: 363 RFEQIDIVSKINENPAI---LVPSNLLYSSTPETIALVSNQI--SQRYFNGSVDLEGFIN 417
              +  +  +      I   L  +  L + T E + LV  +   +    +  +     ++
Sbjct: 241 YIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMD 300

Query: 418 MCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVL 477
           +  D+ + Y  L  A     AG  PV+LY+F +    +  +      +GA H D++ ++ 
Sbjct: 301 IVQDATFVYATLQTAHYHRDAG-LPVYLYEFEHHARGIIVKP---RTDGADHGDEMYFLF 356

Query: 478 KVNSASGTSSSQK---ADDEMKYWMTTFVTNFMRCSAPMCDETTAWP 521
               A+G S  ++   +   MKYW      NF R   P       WP
Sbjct: 357 GGPFATGLSMGKEKALSLQMMKYW-----ANFARTGNPNDGNLPCWP 398


>M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.
          Length = 507

 Score =  101 bits (241), Expect = 9e-21
 Identities = 123/515 (23%), Positives = 196/515 (38%), Gaps = 45/515 (8%)

Query: 66  GELRFKELQPAEPWTDYLDATEEGPVCYQTDVLYGSLMK----------PHGMNEACIYA 115
           G LRF   QPAEPW+   +AT   P+C Q D   G L+           P  ++E C+Y 
Sbjct: 1   GPLRFTPPQPAEPWSFVKNATSYPPMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYL 59

Query: 116 NIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYR 175
           NI+ P        +   K  LP++V+IH              G       NVVV+T  YR
Sbjct: 60  NIYTP-------ADLTKKNRLPVMVWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYR 111

Query: 176 LNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXX 235
           L  +GFFS       GN G  D V  LRWV+ N  +FGGNP +V                
Sbjct: 112 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 171

Query: 236 XXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLV 292
                + L  RAI  SG                  ++  +     +T+   +H   +K  
Sbjct: 172 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTE 231

Query: 293 AMPVEKLNEANRILIDQIG-LTTFFPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIG 351
              +E   +   + +D  G      P++ T   G+  +L + P  L  +     +P ++G
Sbjct: 232 EELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVG 289

Query: 352 FTNSEC-HMFQRRFEQIDI-VSKINENPAILVPSNLLYSSTPETIALVSNQI---SQRYF 406
               E   +   +     +   ++++  A+    +LL+ S P  + +    I   +++Y 
Sbjct: 290 INKQEFGWLIPMQLMSYPLSEGQLDQKTAM----SLLWKSYP-LVCIAKELIPEATEKYL 344

Query: 407 NGSVDL----EGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHL 462
            G+ D     + F+++  D  +  P++ +A     AG AP ++Y+F Y     F      
Sbjct: 345 GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKP 401

Query: 463 HFNGAGHADDLTYVLKVNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPP 522
                 H D+L  V         +S ++    +   +  F  NF R   P  +    WP 
Sbjct: 402 KTVIGDHGDELFSVFGAPFLKEGASEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPE 459

Query: 523 VTPRELQYQDIITPNLCHQTSLTKEQLEMKNFFDK 557
              +E  Y  I       Q    KE     N F K
Sbjct: 460 YNQKE-GYLQIGANTQAAQKLKDKEVAFWTNLFAK 493


>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
          Length = 2768

 Score =   99 bits (238), Expect = 2e-20
 Identities = 86/326 (26%), Positives = 133/326 (40%), Gaps = 24/326 (7%)

Query: 37   GWVCGRSRRAEASTLYAS---FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCY 93
            G + GRS+  +  T +     F GVPYA  P+ E RF+  +P   WT   DA++    C+
Sbjct: 2207 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCW 2265

Query: 94   QTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXX 153
            Q      +   P G++E C+Y N+ +P    P A          +LVF H          
Sbjct: 2266 QPGTRTST--SP-GVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESEG 2313

Query: 154  XXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAF 212
                   +L    N++V+T +YR+  FGF S  + +V GN GL D V  L WV+ + R F
Sbjct: 2314 WPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGF 2373

Query: 213  GGNPDNVX-XXXXXXXXXXXXXXXXXKATEG-LVSRAILMSGAGXXXXXXXXXXXXXXIN 270
            GG+P  V                   +AT   L  RA+LM G+                 
Sbjct: 2374 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQA 2433

Query: 271  KLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTIL 330
              L   +    ++  E+   L   P   LN+A   L+   G   ++  V   H      L
Sbjct: 2434 IALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGH-----FL 2488

Query: 331  DEDPNILVQQGRGKDIPLIIGFTNSE 356
             E P   +++    ++ L+IG +  +
Sbjct: 2489 REPPARALKRSLXVEVDLLIGSSQDD 2514


>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
          Length = 1124

 Score = 99.5 bits (237), Expect = 3e-20
 Identities = 86/326 (26%), Positives = 133/326 (40%), Gaps = 24/326 (7%)

Query: 37  GWVCGRSRRAEASTLYAS---FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCY 93
           G + GRS+  +  T +     F GVPYA  P+ E RF+  +P   WT   DA++    C+
Sbjct: 563 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCW 621

Query: 94  QTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXX 153
           Q      +   P G++E C+Y N+ +P    P A          +LVF H          
Sbjct: 622 QPGTRTST--SP-GVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESEG 669

Query: 154 XXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAF 212
                  +L    N++V+T +YR+  FGF S  + +V GN GL D V  L WV+ + R F
Sbjct: 670 WPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGF 729

Query: 213 GGNPDNVX-XXXXXXXXXXXXXXXXXKATEG-LVSRAILMSGAGXXXXXXXXXXXXXXIN 270
           GG+P  V                   +AT   L  RA+LM G+                 
Sbjct: 730 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQA 789

Query: 271 KLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTIL 330
             L   +    ++  E+   L   P   LN+A   L+   G   ++  V   H      L
Sbjct: 790 IALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGH-----FL 844

Query: 331 DEDPNILVQQGRGKDIPLIIGFTNSE 356
            E P   +++    ++ L+IG +  +
Sbjct: 845 REPPARALKRSLWVEVDLLIGSSQDD 870


>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
            variant protein.
          Length = 1574

 Score = 99.5 bits (237), Expect = 3e-20
 Identities = 86/326 (26%), Positives = 133/326 (40%), Gaps = 24/326 (7%)

Query: 37   GWVCGRSRRAEASTLYAS---FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCY 93
            G + GRS+  +  T +     F GVPYA  P+ E RF+  +P   WT   DA++    C+
Sbjct: 1013 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCW 1071

Query: 94   QTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXX 153
            Q      +   P G++E C+Y N+ +P    P A          +LVF H          
Sbjct: 1072 QPGTRTST--SP-GVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESEG 1119

Query: 154  XXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAF 212
                   +L    N++V+T +YR+  FGF S  + +V GN GL D V  L WV+ + R F
Sbjct: 1120 WPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGF 1179

Query: 213  GGNPDNVX-XXXXXXXXXXXXXXXXXKATEG-LVSRAILMSGAGXXXXXXXXXXXXXXIN 270
            GG+P  V                   +AT   L  RA+LM G+                 
Sbjct: 1180 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQA 1239

Query: 271  KLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTIL 330
              L   +    ++  E+   L   P   LN+A   L+   G   ++  V   H      L
Sbjct: 1240 IALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGH-----FL 1294

Query: 331  DEDPNILVQQGRGKDIPLIIGFTNSE 356
             E P   +++    ++ L+IG +  +
Sbjct: 1295 REPPARALKRSLWVEVDLLIGSSQDD 1320


>X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for
           bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
          Length = 745

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 244



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 412 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 467

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 468 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 524


>M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 244



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 412 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 467

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 468 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 524


>M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase
           protein.
          Length = 747

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 244



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 412 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 467

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 468 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 524


>M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipase
           protein.
          Length = 742

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 28  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 84

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 85  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 140

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 141 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 200

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 201 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 241



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 409 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 464

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 465 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 521


>AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase
           (bile salt-stimulated lipase) protein.
          Length = 756

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 244



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 412 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 467

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 468 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 524


>AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lipase
           oncofetal isoform protein.
          Length = 612

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 8   TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 64

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 65  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 120

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 121 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 180

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 181 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 221



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 389 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 444

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 445 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 501


>AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score = 99.1 bits (236), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 97/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 31  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 87

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 88  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 143

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 144 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 203

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+ RAI  SG
Sbjct: 204 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSG 244



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 412 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 467

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 468 KPFATPT-GYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 524


>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
          Length = 2767

 Score = 97.5 bits (232), Expect = 1e-19
 Identities = 85/326 (26%), Positives = 132/326 (40%), Gaps = 24/326 (7%)

Query: 37   GWVCGRSRRAEASTLYAS---FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCY 93
            G + GRS+  +  T +     F GVPYA  P+ E  F+  +P   WT   DA++    C+
Sbjct: 2206 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERHFQAPEPLN-WTGSWDASKPRASCW 2264

Query: 94   QTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXX 153
            Q      +   P G++E C+Y N+ +P    P A          +LVF H          
Sbjct: 2265 QPGTRTST--SP-GVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESEG 2312

Query: 154  XXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAF 212
                   +L    N++V+T +YR+  FGF S  + +V GN GL D V  L WV+ + R F
Sbjct: 2313 WPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGF 2372

Query: 213  GGNPDNVX-XXXXXXXXXXXXXXXXXKATEG-LVSRAILMSGAGXXXXXXXXXXXXXXIN 270
            GG+P  V                   +AT   L  RA+LM G+                 
Sbjct: 2373 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQA 2432

Query: 271  KLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPGITTIL 330
              L   +    ++  E+   L   P   LN+A   L+   G   ++  V   H      L
Sbjct: 2433 IALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGH-----FL 2487

Query: 331  DEDPNILVQQGRGKDIPLIIGFTNSE 356
             E P   +++    ++ L+IG +  +
Sbjct: 2488 REPPARALKRSLWVEVDLLIGSSQDD 2513


>AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.
          Length = 816

 Score = 97.5 bits (232), Expect = 1e-19
 Identities = 122/503 (24%), Positives = 191/503 (37%), Gaps = 65/503 (12%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT--------DVL-------Y 99
           + GVPYA  P GE RF+  +P   WT   + T+   VC Q         D+L        
Sbjct: 54  YLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANL 113

Query: 100 GSLMK-PHGMNEACIYANIHVPLY-----ALPAAGETPTKPG-----------LPILVFI 142
            +LM      NE C+Y NI+VP          A   T    G            P++V+I
Sbjct: 114 DTLMTYVQDQNEDCLYLNIYVPTEDGANTKKNADDITSNDRGEDEDIHDQNSKKPVMVYI 173

Query: 143 HXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLL 202
           H            + G       NV+VIT NYRL   GF S       GN GL D +  L
Sbjct: 174 HGGSYMEGTGNM-IDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQAL 232

Query: 203 RWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXX 262
           RW++ N  AFGG+P  V                    +EGL  +AI+ S  G        
Sbjct: 233 RWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTALSSWAV 290

Query: 263 XXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFFPVVETP 322
                   ++L   +G N  +  ++ E L     ++L    + +        F PV++  
Sbjct: 291 NYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFGPVID-- 346

Query: 323 HPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPAILVP 382
                 ++ +DP IL++QG   +  +++G    E   F      +D    +  N      
Sbjct: 347 ----GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPNDFDFSV 400

Query: 383 SNL---LY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAE 433
           SN    LY       +  ETI  +    + +  N     +  + + TD  +  PA+  A+
Sbjct: 401 SNFVDNLYGYPEGKDTLRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAPAV-AAD 458

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQ 489
             +  G +P + Y F +   S  K +    +  + H D++ YV  +     T     +  
Sbjct: 459 LHAQYG-SPTYFYAFYHHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTELFSCNFS 513

Query: 490 KADDEMKYWMTTFVTNFMRCSAP 512
           K D  +   + T+ TNF +   P
Sbjct: 514 KNDVMLSAVVMTYWTNFAKTGDP 536


>X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage
           serine-esterase 1 protein.
          Length = 503

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 120/510 (23%), Positives = 191/510 (37%), Gaps = 44/510 (8%)

Query: 70  FKELQPAEPWTDYLDATEEGPVCYQTDVLYGSLMK----------PHGMNEACIYANIHV 119
           F   QPAEPW+   +AT   P+C Q D   G L+           P  ++E C+Y NI+ 
Sbjct: 2   FTPPQPAEPWSFVKNATSYPPMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 60

Query: 120 PLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFF 179
           P        +   K  LP++V+IH              G       NVVV+T  YRL  +
Sbjct: 61  P-------ADLTKKNRLPVMVWIHGGGLMVGAASTY-DGLALAAHENVVVVTIQYRLGIW 112

Query: 180 GFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKA 239
           GFFS       GN G  D V  LRWV+ N  +FGGNP +V                    
Sbjct: 113 GFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPL 172

Query: 240 TEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIH---EKLVAMPV 296
            + L  RAI  SG                  ++  +     +T+   +H   +K     +
Sbjct: 173 AKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELL 232

Query: 297 EKLNEANRILIDQIG-LTTFFPVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNS 355
           E   +   + +D  G      P++ T   G+  +L + P  L  +     +P ++G    
Sbjct: 233 ETTLKMKFLSLDLQGDPRESQPLLGTVIDGM--LLLKTPEELQAERNFHTVPYMVGINKQ 290

Query: 356 ECHMFQRRFEQIDI-VSKINENPAILVPSNLLYSSTPETIALVSNQI---SQRYFNGSVD 411
           E            +   ++++  A+    +LL+ S P  + +    I   +++Y  G+ D
Sbjct: 291 EFGWLIPMLMSYPLSEGQLDQKTAM----SLLWKSYP-LVCIAKELIPEATEKYLGGTDD 345

Query: 412 L----EGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGA 467
                + F+++  D  +  P++ +A     AG AP ++Y+F Y     F           
Sbjct: 346 TVKKKDLFLDLIADVMFGVPSVIVARNHRDAG-APTYMYEFQY--RPSFSSDMKPKTVIG 402

Query: 468 GHADDLTYVLKVNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDETTAWPPVTPRE 527
            H D+L  V         +S ++    +   +  F  NF R   P  +    WP    +E
Sbjct: 403 DHGDELFSVFGAPFLKEGASEEEI--RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKE 460

Query: 528 LQYQDIITPNLCHQTSLTKEQLEMKNFFDK 557
             Y  I       Q    KE     N F K
Sbjct: 461 -GYLQIGANTQAAQKLKDKEVAFWTNLFAK 489


>S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipase
           protein.
          Length = 742

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 69/221 (31%), Positives = 96/221 (43%), Gaps = 9/221 (4%)

Query: 34  TESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVC 92
           TE G+V G +++          F+G+P+A  P   L  +  QP   W   L A      C
Sbjct: 28  TEGGFVEGVNKKLGLLGDSVDIFKGIPFAA-PTKAL--ENPQPHPGWQGTLKAKNFKKRC 84

Query: 93  YQTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXX 152
            Q  +   S    +G +E C+Y NI VP      + + P    +    F+          
Sbjct: 85  LQATITQDST---YG-DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFL 140

Query: 153 XXXLYGPEYLVTR-NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARA 211
              LY  E + TR NV+V+TFNYR+   GF S     +PGN GLRD    + WVKRN  A
Sbjct: 141 NNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAA 200

Query: 212 FGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSG 252
           FGG+P+N+                     +GL+  AI  SG
Sbjct: 201 FGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRAAISQSG 241



 Score = 39.5 bits (88), Expect = 0.031
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 420 TDSYYKYPA-LNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLK 478
           TD  +  P  + LA+ R+ A  A  + Y FS+      +   +  + GA HADD+ YV  
Sbjct: 409 TDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPS----RMPVYPKWVGADHADDIQYVFG 464

Query: 479 VNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMCDET---TAWPPVTPRELQYQDI 533
              A+ T   +  D  +   M  + TNF +   P   ++   T W P T     Y +I
Sbjct: 465 KPFATPT-GYRPQDRTVFKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEI 521


>BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for
           IMAGE:40133565) protein.
          Length = 422

 Score = 96.7 bits (230), Expect = 2e-19
 Identities = 69/223 (30%), Positives = 100/223 (44%), Gaps = 19/223 (8%)

Query: 37  GWVCGRSRRAEASTLYAS---FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCY 93
           G + GRS+  +  T +     F GVPYA  P+ E RF+  +P   WT   DA++    C+
Sbjct: 169 GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCW 227

Query: 94  QTDVLYGSLMKPHGMNEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXX 153
           Q      +   P G++E C+Y N+ +P    P A          +LVF H          
Sbjct: 228 QPGTRTST--SP-GVSEDCLYLNVFIPQNVAPNAS---------VLVFFHNTMDREESEG 275

Query: 154 XXLYGPEYLVT-RNVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAF 212
                  +L    N++V+T +YR+  FGF S  + +V GN GL D V  L WV+ + R F
Sbjct: 276 WPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGF 335

Query: 213 GGNPDNVX-XXXXXXXXXXXXXXXXXKATEG-LVSRAILMSGA 253
           GG+P  V                   +AT   L  RA+LM G+
Sbjct: 336 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGS 378


>AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 545

 Score = 86.2 bits (204), Expect = 3e-16
 Identities = 63/251 (25%), Positives = 102/251 (40%), Gaps = 13/251 (5%)

Query: 109 NEACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRNVV 168
           +E C+Y N++ P  A       P  P LP++V+                G +      VV
Sbjct: 217 SEDCLYLNVYAPARA-------PGDPQLPVMVWFPGGAFIVGAASSY-EGSDLAAREKVV 268

Query: 169 VITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXX 228
           ++   +RL  FGF S D     GN GL D +  LRWV+ N  AFGG+P NV         
Sbjct: 269 LVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGA 328

Query: 229 XXXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIH 288
                        GL  RAI  S +G              + K +  + G N  +   + 
Sbjct: 329 MSISGLMMSPLASGLFHRAI--SQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILV 386

Query: 289 EKLVAMPVEK-LNEANRILIDQIGLTTF-FPVVETPHPGIT-TILDEDPNILVQQGRGKD 345
             L A+   K +  +N++   Q+        ++ +  P +   ++ +DP +L+ QG+   
Sbjct: 387 NCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSS 446

Query: 346 IPLIIGFTNSE 356
           +P ++G  N E
Sbjct: 447 VPYLLGVNNLE 457



 Score = 40.3 bits (90), Expect = 0.018
 Identities = 17/36 (47%), Positives = 22/36 (61%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGP 90
           F GVP+++ P+G LRF   +P EPW    DAT   P
Sbjct: 115 FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPP 150


>AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.
          Length = 679

 Score = 86.2 bits (204), Expect = 3e-16
 Identities = 90/389 (23%), Positives = 150/389 (38%), Gaps = 32/389 (8%)

Query: 137 PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLR 196
           P++V+IH            + G       NV+VIT NYRL   GF S       GN GL 
Sbjct: 30  PVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 88

Query: 197 DMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXX 256
           D +  LRW++ N  AFGG+P  V                    +EGL  +AI+ S  G  
Sbjct: 89  DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS--GTA 146

Query: 257 XXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFF 316
                         ++L   +G N  +  ++ E L     ++L    + +        F 
Sbjct: 147 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFG 204

Query: 317 PVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINEN 376
           PV++        ++ +DP IL++QG   +  +++G    E   F      +D    +  N
Sbjct: 205 PVID------GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI--VDNEDGVTPN 256

Query: 377 PAILVPSNL---LY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYP 427
                 SN    LY       +  ETI  +    + +  N     +  + + TD  +  P
Sbjct: 257 DFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKE-NPETRRKTLVALFTDHQWVAP 315

Query: 428 ALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS- 486
           A+  A+  +  G +P + Y F +   S  K +    +  + H D++ YV  +     T  
Sbjct: 316 AVATADLHAQYG-SPTYFYAFYHHCQSEMKPS----WADSAHGDEVPYVFGIPMIGPTEL 370

Query: 487 ---SSQKADDEMKYWMTTFVTNFMRCSAP 512
              +  K D  +   + T+ TNF +   P
Sbjct: 371 FSCNFSKNDVMLSAVVMTYWTNFAKTGDP 399


>AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 848

 Score = 85.8 bits (203), Expect = 4e-16
 Identities = 92/387 (23%), Positives = 155/387 (40%), Gaps = 28/387 (7%)

Query: 137 PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLR 196
           P++V+IH            + G       NV+VIT NYR+   GF S       GN GL 
Sbjct: 201 PVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 259

Query: 197 DMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXX 256
           D +  LRWV  N   FGG+P  +                    +EGL  RAI+ SG+   
Sbjct: 260 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 319

Query: 257 XXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFF 316
                          LL   +G N  +  ++ + L     ++L E +  +        F 
Sbjct: 320 SWAVNYQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFG 375

Query: 317 PVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINE 375
           PV++        ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + 
Sbjct: 376 PVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDF 429

Query: 376 NPAILVPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPAL 429
           + ++    + LY       +  ETI  +    + R  N     +  + + TD  +  P++
Sbjct: 430 DYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSV 488

Query: 430 NLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS--- 486
             A+  +  G +P + Y F +   S+ K A    ++ A H D++ YV  V     T    
Sbjct: 489 VTADLHARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGVPMVGPTDLFP 543

Query: 487 -SSQKADDEMKYWMTTFVTNFMRCSAP 512
            +  K D  +   + T+ TNF +   P
Sbjct: 544 CNFSKNDVMLSAVVMTYWTNFAKTGDP 570



 Score = 41.9 bits (94), Expect = 0.006
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 15/81 (18%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT-DVLYGSLMKP-------- 105
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q        +M P        
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 106 ------HGMNEACIYANIHVP 120
                    NE C+Y N++VP
Sbjct: 129 IVATYIQEPNEDCLYLNVYVP 149


>AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.
          Length = 682

 Score = 85.8 bits (203), Expect = 4e-16
 Identities = 92/387 (23%), Positives = 155/387 (40%), Gaps = 28/387 (7%)

Query: 137 PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLR 196
           P++V+IH            + G       NV+VIT NYR+   GF S       GN GL 
Sbjct: 35  PVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 93

Query: 197 DMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXX 256
           D +  LRWV  N   FGG+P  +                    +EGL  RAI+ SG+   
Sbjct: 94  DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 153

Query: 257 XXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFF 316
                          LL   +G N  +  ++ + L     ++L E +  +        F 
Sbjct: 154 SWAVNYQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFG 209

Query: 317 PVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINE 375
           PV++        ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + 
Sbjct: 210 PVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDF 263

Query: 376 NPAILVPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPAL 429
           + ++    + LY       +  ETI  +    + R  N     +  + + TD  +  P++
Sbjct: 264 DYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSV 322

Query: 430 NLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS--- 486
             A+  +  G +P + Y F +   S+ K A    ++ A H D++ YV  V     T    
Sbjct: 323 VTADLHARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGVPMVGPTDLFP 377

Query: 487 -SSQKADDEMKYWMTTFVTNFMRCSAP 512
            +  K D  +   + T+ TNF +   P
Sbjct: 378 CNFSKNDVMLSAVVMTYWTNFAKTGDP 404


>AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HNL3s
           protein.
          Length = 558

 Score = 81.8 bits (193), Expect = 6e-15
 Identities = 84/350 (24%), Positives = 142/350 (40%), Gaps = 24/350 (6%)

Query: 137 PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLR 196
           P++V+IH            + G       NV+VIT NYR+   GF S       GN GL 
Sbjct: 201 PVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 259

Query: 197 DMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXX 256
           D +  LRWV  N   FGG+P  +                    +EGL  RAI+ SG+   
Sbjct: 260 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 319

Query: 257 XXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFF 316
                          LL   +G N  +  ++ + L     ++L E +  +        F 
Sbjct: 320 SWAVNYQPVKYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFG 375

Query: 317 PVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINE 375
           PV++        ++ +DP IL++QG   +  +++G    E   F +   +  D VS  + 
Sbjct: 376 PVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDF 429

Query: 376 NPAILVPSNLLY------SSTPETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPAL 429
           + ++    + LY       +  ETI  +    + R  N     +  + + TD  +  P++
Sbjct: 430 DYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR-DNPETRRKTLVALFTDHQWVEPSV 488

Query: 430 NLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKV 479
             A+  +  G +P + Y F +   S+ K A    ++ A H D++ YV  V
Sbjct: 489 VTADLHARYG-SPTYFYAFYHHCQSLMKPA----WSDAAHGDEVPYVFGV 533



 Score = 41.9 bits (94), Expect = 0.006
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 15/81 (18%)

Query: 55  FRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEGPVCYQT-DVLYGSLMKP-------- 105
           + GVPYA  P+GE RF   +P   W+   +AT   PVC Q        +M P        
Sbjct: 69  YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128

Query: 106 ------HGMNEACIYANIHVP 120
                    NE C+Y N++VP
Sbjct: 129 IVATYIQEPNEDCLYLNVYVP 149


>M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.
          Length = 454

 Score = 77.0 bits (181), Expect = 2e-13
 Identities = 105/463 (22%), Positives = 170/463 (36%), Gaps = 38/463 (8%)

Query: 110 EACIYANIHVPLYALPAAGETPTKPGLPILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVV 169
           E C+Y NI+ P        +   K  LP++V+IH              G       NVVV
Sbjct: 1   EHCLYLNIYTP-------ADLTKKNRLPVMVWIHGGGLMVGAASTY-DGLALAAHENVVV 52

Query: 170 ITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXX 229
           +T  YRL  +GFFS       GN G  D V  LRWV+ N  +FGGNP +V          
Sbjct: 53  VTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGE 112

Query: 230 XXXXXXXXKATEGLVSRAILMSGAGXXXXXXXXXXXXXXINKLLFSILGVNSTNPDEIHE 289
                      + L  RAI  SG                  ++  +  G  +T    +  
Sbjct: 113 SVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAIT-AGCKTTTSAAMVH 171

Query: 290 KLVAMPVEKLNEANRILIDQIGLTTFFPVVETPHPG--ITTILD-----EDPNILVQQGR 342
            L     E+L E       +IG +  +   ET      + T++D     + P  L ++  
Sbjct: 172 CLRQKTEEELLETTL----KIGNSYLWTYRETQRESTLLGTVIDGMLLLKTPEELQRERN 227

Query: 343 GKDIPLIIGFTNSEC-HMFQRRFEQIDI-VSKINENPAI-LVPSNL-LYSSTPETIALVS 398
              +P ++G    E   +   +     +   ++++  A+ L+ S + L++   E I    
Sbjct: 228 FHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLGSPIPLFAIAKELIP--- 284

Query: 399 NQISQRYFNGSVDL----EGFINMCTDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYS 454
            + +++Y  G+ D     +  +++  D  +  P++ +A     AG AP ++Y+F Y    
Sbjct: 285 -EATEKYLGGTDDTVKKKDLILDLIADVMFGVPSVIVARNHRDAG-APTYMYEFQY--RP 340

Query: 455 VFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQKADDEMKYWMTTFVTNFMRCSAPMC 514
            F            H D+L  V         +S ++    +   +  F  NF R   P  
Sbjct: 341 SFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEI--RLSKMVMKFWANFARNGNPNG 398

Query: 515 DETTAWPPVTPRELQYQDIITPNLCHQTSLTKEQLEMKNFFDK 557
                WP    +E  Y  I       Q    KE     N F K
Sbjct: 399 KGLPHWPEYNQKE-GYLQIGANTQAAQKLKDKEVAFWTNLFAK 440


>BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein
           protein.
          Length = 351

 Score = 72.9 bits (171), Expect = 3e-12
 Identities = 56/220 (25%), Positives = 88/220 (40%), Gaps = 11/220 (5%)

Query: 137 PILVFIHXXXXXXXXXXXXLYGPEYLVTRNVVVITFNYRLNFFGFFSLDTPKVPGNNGLR 196
           P++V+IH            + G       NV+VIT NYR+   GF S       GN GL 
Sbjct: 64  PVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 122

Query: 197 DMVTLLRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXX 256
           D +  LRWV  N   FGG+P  +                    +EGL  RAI+ SG+   
Sbjct: 123 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 182

Query: 257 XXXXXXXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEKLNEANRILIDQIGLTTFF 316
                          LL   +G N  +  ++ + L     ++L E +  +        F 
Sbjct: 183 SWAVNYQPVEYT--SLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARYHVAFG 238

Query: 317 PVVETPHPGITTILDEDPNILVQQGRGKDIPLIIGFTNSE 356
           PV++        ++ +DP IL++QG   +  +++G    E
Sbjct: 239 PVIDGD------VIPDDPEILMEQGEFLNYDIMLGVNQGE 272


>AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
           LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
          Length = 367

 Score = 69.3 bits (162), Expect = 3e-11
 Identities = 72/331 (21%), Positives = 129/331 (38%), Gaps = 22/331 (6%)

Query: 202 LRWVKRNARAFGGNPDNVXXXXXXXXXXXXXXXXXXKATEGLVSRAILMSGAGXXXXXXX 261
           LRWV+ N  AFGG+P NV                      GL  RAI  S +G       
Sbjct: 4   LRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAI--SQSGTALFRPF 61

Query: 262 XXXXXXXINKLLFSILGVNSTNPDEIHEKLVAMPVEK-LNEANRILIDQIGLTTF-FPVV 319
                  + K +  + G N  +   +   L A+   K +  +N++   Q+        ++
Sbjct: 62  ITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEII 121

Query: 320 ETPHPGIT-TILDEDPNILVQQGRGKDIPLIIGFTNSECHMFQRRFEQIDIVSKINENPA 378
            +  P +   ++ +DP +L+ QG+   +P ++G  N E +       +  +  +      
Sbjct: 122 WSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKET 181

Query: 379 I---LVPSNLLYSSTPETIALVSNQI--SQRYFNGSVDLEGFINMCTDSYYKYPALNLAE 433
           I   L  +  L + T E + LV  +   +    +  +     +++  D+ + Y  L  A 
Sbjct: 182 ITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAH 241

Query: 434 KRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTSSSQK--- 490
               AG  PV+LY+F +    +  +      +GA H D++ ++     A+G S  ++   
Sbjct: 242 YHRDAG-LPVYLYEFEHHARGIIVKP---RTDGADHGDEMYFLFGGPFATGLSMGKEKAL 297

Query: 491 ADDEMKYWMTTFVTNFMRCSAPMCDETTAWP 521
           +   MKYW      NF R   P       WP
Sbjct: 298 SLQMMKYW-----ANFARTGNPNDGNLPCWP 323


>BC009706-1|AAH09706.1|  150|Homo sapiens CES1 protein protein.
          Length = 150

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 15/120 (12%)

Query: 31  VAQTESGWVCGRSRRAEA-STLYASFRGVPYAKQPVGELRFKELQPAEPWTDYLDATEEG 89
           V  T  G V G+    E  +   A F G+P+AK P+G LRF   QPAEPW+   +AT   
Sbjct: 26  VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 85

Query: 90  PVCYQTDVLYGSLMK----------PHGMNEACIYANIHVPLYA---LPAAGETPTKPGL 136
           P+C Q D   G L+           P  ++E C+Y NI+ P      LP AG   T P L
Sbjct: 86  PMCTQ-DPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTRWLPCAGSRTTLPAL 144


>BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.
          Length = 151

 Score = 63.3 bits (147), Expect = 2e-09
 Identities = 33/87 (37%), Positives = 40/87 (45%)

Query: 166 NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXX 225
           NVVV+T  YRL  +GFFS      PGN G  D +  L WV+ N  +FGGNP +V      
Sbjct: 27  NVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAALHWVQDNIASFGGNPGSVTIFGGS 86

Query: 226 XXXXXXXXXXXXKATEGLVSRAILMSG 252
                          + L  RAI  SG
Sbjct: 87  AGGESVSVLVLSPLAKNLFHRAISESG 113


>AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40219 fis, clone TESTI2021637, moderately
           similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
           3.1.1.1). ).
          Length = 207

 Score = 63.3 bits (147), Expect = 2e-09
 Identities = 33/87 (37%), Positives = 39/87 (44%)

Query: 166 NVVVITFNYRLNFFGFFSLDTPKVPGNNGLRDMVTLLRWVKRNARAFGGNPDNVXXXXXX 225
           +VVV+T  YRL   GFFS      PGN G  D+V  LRWV+ N   FGG+ + V      
Sbjct: 27  DVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGS 86

Query: 226 XXXXXXXXXXXXKATEGLVSRAILMSG 252
                           GL  RAI  SG
Sbjct: 87  AGGSIISGLVLSPVAAGLFHRAITQSG 113


>BC025347-1|AAH25347.1|  441|Homo sapiens KIAA0692 protein protein.
          Length = 441

 Score = 37.1 bits (82), Expect = 0.17
 Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 17/141 (12%)

Query: 360 FQRRFEQIDIVSKINENPAILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLEGFINMC 419
           F  +F   D+V+ ++ +  I+  S   Y  TPE +      I +R  N SV+L+  I   
Sbjct: 211 FACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDV------ICERSKNKSVELKERIREY 264

Query: 420 TDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKV 479
              +Y  P L  AE+ S    +PV    +S D  +   +A H+   G    D    VL +
Sbjct: 265 LKGHYYVPLLR-AEETS----SPVIGELWSPDQTA---EASHVSRYGGSPRDP---VLTL 313

Query: 480 NSASGTSSSQKADDEMKYWMT 500
            + +G  S  KA+D  K W T
Sbjct: 314 RAFAGPLSPAKAEDFRKLWKT 334


>BC001530-1|AAH01530.2|  441|Homo sapiens KIAA0692 protein protein.
          Length = 441

 Score = 37.1 bits (82), Expect = 0.17
 Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 17/141 (12%)

Query: 360 FQRRFEQIDIVSKINENPAILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLEGFINMC 419
           F  +F   D+V+ ++ +  I+  S   Y  TPE +      I +R  N SV+L+  I   
Sbjct: 211 FACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDV------ICERSKNKSVELKERIREY 264

Query: 420 TDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKV 479
              +Y  P L  AE+ S    +PV    +S D  +   +A H+   G    D    VL +
Sbjct: 265 LKGHYYVPLLR-AEETS----SPVIGELWSPDQTA---EASHVSRYGGSPRDP---VLTL 313

Query: 480 NSASGTSSSQKADDEMKYWMT 500
            + +G  S  KA+D  K W T
Sbjct: 314 RAFAGPLSPAKAEDFRKLWKT 334


>AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.
          Length = 550

 Score = 37.1 bits (82), Expect = 0.17
 Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 17/195 (8%)

Query: 329 ILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAILVPSNLLY 387
           ++ +DP IL+QQG   +  ++IG    E   F +   E  D VS    +  +    + LY
Sbjct: 74  VVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLY 133

Query: 388 SSTP------ETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDA 441
                     ETI  +    + R  NG +  +  + + TD  +  PA+  A K      +
Sbjct: 134 GYPEGKDVLRETIKFMYTDWADR-DNGEMRRKTLLALFTDHQWVAPAVATA-KLHADYQS 191

Query: 442 PVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKY 497
           PV+ Y F    Y   +      +  A H D+L YV  V     T     +  K D  +  
Sbjct: 192 PVYFYTF----YHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSA 247

Query: 498 WMTTFVTNFMRCSAP 512
            + T+ TNF +   P
Sbjct: 248 VVMTYWTNFAKTGDP 262


>AB014592-1|BAA31667.1|  783|Homo sapiens KIAA0692 protein protein.
          Length = 783

 Score = 37.1 bits (82), Expect = 0.17
 Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 17/141 (12%)

Query: 360 FQRRFEQIDIVSKINENPAILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLEGFINMC 419
           F  +F   D+V+ ++ +  I+  S   Y  TPE +      I +R  N SV+L+  I   
Sbjct: 263 FACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDV------ICERSKNKSVELKERIREY 316

Query: 420 TDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKV 479
              +Y  P L  AE+ S    +PV    +S D  +   +A H+   G    D    VL +
Sbjct: 317 LKGHYYVPLLR-AEETS----SPVIGELWSPDQTA---EASHVSRYGGSPRDP---VLTL 365

Query: 480 NSASGTSSSQKADDEMKYWMT 500
            + +G  S  KA+D  K W T
Sbjct: 366 RAFAGPLSPAKAEDFRKLWKT 386


>BC043157-1|AAH43157.2|  938|Homo sapiens KIAA0692 protein protein.
          Length = 938

 Score = 35.9 bits (79), Expect = 0.38
 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 17/141 (12%)

Query: 360 FQRRFEQIDIVSKINENPAILVPSNLLYSSTPETIALVSNQISQRYFNGSVDLEGFINMC 419
           F  +F   D+V+ ++ +  I+  S   Y  TPE +      I +R  N SV+L+  I   
Sbjct: 418 FACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDV------ICERSKNKSVELKERIREY 471

Query: 420 TDSYYKYPALNLAEKRSTAGDAPVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKV 479
              +Y  P +  AE+ S    +PV    +S D  +   +A H+   G    D    VL +
Sbjct: 472 LKGHYYVPLVR-AEETS----SPVIGELWSPDQTA---EASHVSRYGGSPRDP---VLTL 520

Query: 480 NSASGTSSSQKADDEMKYWMT 500
            + +G  S  KA+D  K W T
Sbjct: 521 RAFAGPLSPAKAEDFRKLWKT 541


>AK074522-1|BAC11039.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90041 fis, clone HEMBA1002167, highly similar to
           Rattus norvegicus neuroligin I mRNA. ).
          Length = 509

 Score = 35.5 bits (78), Expect = 0.51
 Identities = 44/195 (22%), Positives = 82/195 (42%), Gaps = 17/195 (8%)

Query: 329 ILDEDPNILVQQGRGKDIPLIIGFTNSECHMF-QRRFEQIDIVSKINENPAILVPSNLLY 387
           ++ +DP IL++QG   +  +++G    E   F +   +  D +S  + + A+    + LY
Sbjct: 50  VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLY 109

Query: 388 SSTP------ETIALVSNQISQRYFNGSVDLEGFINMCTDSYYKYPALNLAEKRSTAGDA 441
                     ETI  +    + R+ N     +  + + TD  +  PA+  A+  S  G +
Sbjct: 110 GYPEGKDVLRETIKFMYTDWADRH-NPETRRKTLLALFTDHQWVAPAVATADLHSNFG-S 167

Query: 442 PVFLYQFSYDGYSVFKQAFHLHFNGAGHADDLTYVLKVNSASGTS----SSQKADDEMKY 497
           P + Y F +   +    A    +  A H D++ YVL +     T     +  K D  +  
Sbjct: 168 PTYFYAFYHHCQTDQVPA----WADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSA 223

Query: 498 WMTTFVTNFMRCSAP 512
            + T+ TNF +   P
Sbjct: 224 VVMTYWTNFAKTGDP 238


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.137    0.417 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,826,793
Number of Sequences: 224733
Number of extensions: 3295810
Number of successful extensions: 5898
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 5612
Number of HSP's gapped (non-prelim): 151
length of query: 567
length of database: 73,234,838
effective HSP length: 94
effective length of query: 473
effective length of database: 52,109,936
effective search space: 24647999728
effective search space used: 24647999728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)

- SilkBase 1999-2023 -