Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000770-TA|BGIBMGA000770-PA|IPR002889|Carbohydrate-
binding WSC, IPR003961|Fibronectin, type III, IPR001245|Tyrosine
protein kinase, IPR011009|Protein kinase-like, IPR008957|Fibronectin,
type III-like fold, IPR000719|Protein kinase, IPR000834|Peptidase M14,
carboxypeptidase A, IPR013994|Carbohydrate-binding WSC, subgroup,
IPR002290|Serine/threonine protein kinase
(728 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 144 1e-33
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 144 1e-33
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 144 1e-33
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 144 1e-33
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 141 7e-33
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 141 7e-33
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 141 7e-33
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 141 7e-33
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 141 7e-33
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 141 7e-33
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 141 7e-33
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 141 7e-33
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 141 7e-33
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 141 7e-33
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 141 7e-33
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 141 7e-33
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 141 7e-33
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 141 7e-33
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 141 7e-33
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 141 7e-33
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 141 7e-33
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 141 7e-33
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 141 7e-33
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 140 1e-32
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 140 2e-32
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 140 2e-32
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 140 2e-32
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 140 2e-32
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 140 2e-32
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 139 4e-32
DQ836395-1|ABI53804.1| 556|Homo sapiens N2idVEGFR-1 protein. 139 4e-32
DQ836394-1|ABI53803.1| 556|Homo sapiens idVEGFR-1 protein. 139 4e-32
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 138 5e-32
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 138 5e-32
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 138 5e-32
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 138 5e-32
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 138 5e-32
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 138 9e-32
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 138 9e-32
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 138 9e-32
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 138 9e-32
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 138 9e-32
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 137 1e-31
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 137 1e-31
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 137 1e-31
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 137 1e-31
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 137 1e-31
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 137 1e-31
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 137 1e-31
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 137 1e-31
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 137 1e-31
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 137 1e-31
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 137 1e-31
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 137 1e-31
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 137 1e-31
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 137 1e-31
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 137 1e-31
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 137 1e-31
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 137 1e-31
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 136 2e-31
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 135 6e-31
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 135 6e-31
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 135 6e-31
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 135 6e-31
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 135 6e-31
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 135 6e-31
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 135 6e-31
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 135 6e-31
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 135 6e-31
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 134 8e-31
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 134 8e-31
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 134 8e-31
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 134 8e-31
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 134 8e-31
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 134 8e-31
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 134 8e-31
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 134 8e-31
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 134 8e-31
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 134 1e-30
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 134 1e-30
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 134 1e-30
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 134 1e-30
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 134 1e-30
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 134 1e-30
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 134 1e-30
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 134 1e-30
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 132 3e-30
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 132 3e-30
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 132 3e-30
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 132 3e-30
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 130 1e-29
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 130 1e-29
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 130 1e-29
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 130 1e-29
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 130 1e-29
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 130 2e-29
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 130 2e-29
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 130 2e-29
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 130 2e-29
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 130 2e-29
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 130 2e-29
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 130 2e-29
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 130 2e-29
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 130 2e-29
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 130 2e-29
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 129 3e-29
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 129 3e-29
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 129 3e-29
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 129 3e-29
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 129 3e-29
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 129 4e-29
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 129 4e-29
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 129 4e-29
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 129 4e-29
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 129 4e-29
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 129 4e-29
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 129 4e-29
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 129 4e-29
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 128 5e-29
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 128 5e-29
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 128 5e-29
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 128 5e-29
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 128 7e-29
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 128 9e-29
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 127 1e-28
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 127 1e-28
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 127 1e-28
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 127 1e-28
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 127 1e-28
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 127 1e-28
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 127 1e-28
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 127 1e-28
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 127 2e-28
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 127 2e-28
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 127 2e-28
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 127 2e-28
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 127 2e-28
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 127 2e-28
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 127 2e-28
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 127 2e-28
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 127 2e-28
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 127 2e-28
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 127 2e-28
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 127 2e-28
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 127 2e-28
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 126 2e-28
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 126 2e-28
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 126 2e-28
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 126 2e-28
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 126 2e-28
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 126 2e-28
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 126 2e-28
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 125 5e-28
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 125 6e-28
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 124 1e-27
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 124 1e-27
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 124 1e-27
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 124 1e-27
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 124 1e-27
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 124 1e-27
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 123 2e-27
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 123 3e-27
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 123 3e-27
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 123 3e-27
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 122 3e-27
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 122 3e-27
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 122 3e-27
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 122 5e-27
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 122 5e-27
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 122 5e-27
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 121 1e-26
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 121 1e-26
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 121 1e-26
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 120 2e-26
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 120 2e-26
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 120 2e-26
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 120 2e-26
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 120 2e-26
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 120 2e-26
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 120 2e-26
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 120 2e-26
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 120 2e-26
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 120 2e-26
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 120 2e-26
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 120 2e-26
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 120 2e-26
X69878-1|CAA49505.1| 1298|Homo sapiens protein ( H.sapiens Flt4 ... 119 3e-26
X68203-1|CAA48290.1| 1304|Homo sapiens FTL4 protein. 119 3e-26
U43143-1|AAA85215.1| 1298|Homo sapiens Flt4 protein. 119 3e-26
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 119 3e-26
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 119 3e-26
AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein. 119 3e-26
AY233382-1|AAO89504.1| 1298|Homo sapiens VEGFR3 short form protein. 119 3e-26
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 119 4e-26
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 119 4e-26
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 119 4e-26
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 119 4e-26
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 119 4e-26
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 119 4e-26
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 119 4e-26
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 119 4e-26
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 119 4e-26
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 119 4e-26
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 119 4e-26
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 119 4e-26
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 119 4e-26
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 119 4e-26
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 119 4e-26
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 119 4e-26
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 119 4e-26
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 119 4e-26
AB209405-1|BAD92642.1| 232|Homo sapiens RYK receptor-like tyros... 118 6e-26
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 118 7e-26
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 118 7e-26
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 118 7e-26
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 118 7e-26
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 118 7e-26
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 118 7e-26
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 118 7e-26
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 118 7e-26
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 118 7e-26
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 118 7e-26
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 118 7e-26
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 118 7e-26
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 118 7e-26
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 118 7e-26
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 118 1e-25
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 118 1e-25
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 118 1e-25
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 118 1e-25
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 118 1e-25
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 118 1e-25
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 118 1e-25
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 118 1e-25
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 118 1e-25
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 118 1e-25
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 118 1e-25
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 117 1e-25
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 117 1e-25
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 117 1e-25
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 117 1e-25
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 117 1e-25
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 116 2e-25
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 116 2e-25
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 116 3e-25
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 116 3e-25
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 116 3e-25
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 116 4e-25
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 116 4e-25
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 116 4e-25
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 116 4e-25
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 115 5e-25
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 115 5e-25
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 115 5e-25
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 115 5e-25
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 115 5e-25
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 115 7e-25
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 115 7e-25
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 115 7e-25
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 113 2e-24
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 113 2e-24
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 113 2e-24
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 113 2e-24
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 113 2e-24
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 113 2e-24
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 113 2e-24
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 113 2e-24
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 113 3e-24
M21616-1|AAA36427.1| 1106|Homo sapiens platelet-derived growth f... 113 3e-24
J03278-1|AAA60049.1| 1106|Homo sapiens platelet-derived growth f... 113 3e-24
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 113 3e-24
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 113 3e-24
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 113 3e-24
BC032224-1|AAH32224.1| 1106|Homo sapiens platelet-derived growth... 113 3e-24
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 113 3e-24
AB209657-1|BAD92894.1| 777|Homo sapiens platelet-derived growth... 113 3e-24
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 112 4e-24
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 112 4e-24
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 112 5e-24
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 112 5e-24
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 110 1e-23
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 110 1e-23
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 110 1e-23
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 110 1e-23
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 110 1e-23
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 110 1e-23
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 110 1e-23
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 110 1e-23
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 110 1e-23
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 110 2e-23
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 110 2e-23
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 110 2e-23
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 109 3e-23
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 109 3e-23
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 109 3e-23
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 109 3e-23
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 109 3e-23
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 109 3e-23
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 109 3e-23
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 109 3e-23
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 109 3e-23
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 109 5e-23
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 109 5e-23
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 108 6e-23
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 108 6e-23
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 108 6e-23
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 108 6e-23
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 108 6e-23
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 108 6e-23
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 108 6e-23
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 108 6e-23
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 108 6e-23
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 108 6e-23
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 108 6e-23
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 108 6e-23
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 108 6e-23
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 108 6e-23
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 108 8e-23
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 108 8e-23
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 108 8e-23
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 108 8e-23
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 108 8e-23
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 107 1e-22
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 107 1e-22
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 107 1e-22
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 107 1e-22
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 107 1e-22
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 107 1e-22
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 107 1e-22
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 107 1e-22
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 107 1e-22
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 107 1e-22
BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein. 106 2e-22
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 106 3e-22
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 106 3e-22
AC073324-1|AAS07524.1| 387|Homo sapiens unknown protein. 106 3e-22
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 106 3e-22
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 105 4e-22
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 105 4e-22
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 105 4e-22
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 105 4e-22
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 105 4e-22
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 105 4e-22
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 105 4e-22
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 105 4e-22
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 105 4e-22
AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinas... 105 4e-22
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 105 4e-22
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 105 4e-22
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 105 6e-22
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 105 6e-22
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 105 6e-22
AY229892-1|AAP69563.1| 849|Homo sapiens FIP1L1/PDGFRA fusion pr... 105 6e-22
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 105 7e-22
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 105 7e-22
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 105 7e-22
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 105 7e-22
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 105 7e-22
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 105 7e-22
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 105 7e-22
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 105 7e-22
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 104 1e-21
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 104 1e-21
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 104 1e-21
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 104 1e-21
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 104 1e-21
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 104 1e-21
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 104 1e-21
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 104 1e-21
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 104 1e-21
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 104 1e-21
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 104 1e-21
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 104 1e-21
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 104 1e-21
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 104 1e-21
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 104 1e-21
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 104 1e-21
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 104 1e-21
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 103 2e-21
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 103 2e-21
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 103 2e-21
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 103 2e-21
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 103 2e-21
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 103 2e-21
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 103 2e-21
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 103 2e-21
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 103 2e-21
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 103 2e-21
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 103 3e-21
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 103 3e-21
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 103 3e-21
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 103 3e-21
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 103 3e-21
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 102 4e-21
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 102 4e-21
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 102 4e-21
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 102 4e-21
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 102 4e-21
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 102 4e-21
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 102 4e-21
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 102 4e-21
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 102 5e-21
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 102 5e-21
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 102 5e-21
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 102 5e-21
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 102 5e-21
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 102 5e-21
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 102 5e-21
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 102 5e-21
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 102 5e-21
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 101 7e-21
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 101 7e-21
AC012069-1|AAY15092.1| 479|Homo sapiens unknown protein. 101 7e-21
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 101 9e-21
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 101 9e-21
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 101 9e-21
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 101 9e-21
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 101 9e-21
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 101 9e-21
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 101 9e-21
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 101 9e-21
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 101 9e-21
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 101 9e-21
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 101 1e-20
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 101 1e-20
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 101 1e-20
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 101 1e-20
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 101 1e-20
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 100 2e-20
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 100 2e-20
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 100 2e-20
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 99 3e-20
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 99 3e-20
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 99 3e-20
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 99 3e-20
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 99 5e-20
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 99 5e-20
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 99 5e-20
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 99 5e-20
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 99 5e-20
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 99 5e-20
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 99 5e-20
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 98 8e-20
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 98 8e-20
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 98 8e-20
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 98 8e-20
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 98 8e-20
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 98 8e-20
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 98 1e-19
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 98 1e-19
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 98 1e-19
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 98 1e-19
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 98 1e-19
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 98 1e-19
AY563054-1|AAT01226.1| 422|Homo sapiens tyrosine kinase protein... 97 1e-19
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 97 1e-19
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 97 1e-19
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 97 1e-19
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 97 2e-19
AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinem... 97 2e-19
BC071593-1|AAH71593.1| 976|Homo sapiens KIT protein protein. 97 3e-19
AF251059-1|AAK34949.1| 422|Homo sapiens kinase domain protein p... 97 3e-19
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 96 3e-19
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 96 3e-19
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 96 3e-19
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 96 3e-19
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 96 3e-19
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 96 3e-19
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 96 3e-19
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 96 3e-19
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 96 3e-19
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 96 3e-19
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 96 3e-19
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 96 3e-19
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 96 3e-19
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 96 3e-19
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 96 5e-19
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 96 5e-19
BC093824-1|AAH93824.1| 422|Homo sapiens serine/threonine/tyrosi... 96 5e-19
BC093822-1|AAH93822.1| 422|Homo sapiens serine/threonine/tyrosi... 96 5e-19
>L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 1124
Score = 144 bits (349), Expect = 1e-33
Identities = 79/252 (31%), Positives = 133/252 (52%), Gaps = 12/252 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRD- 534
K + + EL++L K H N+I+L+G CE L + +E L + L SR +
Sbjct: 863 KDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLET 922
Query: 535 -----IQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
I N+ +++ ++L VARGM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 923 DPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIAD 982
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS + ++ RW + E L + Y +DVWS+GVL+WE+++LG TPY
Sbjct: 983 FGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGM 1042
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTR 705
++ ++ +G R +P DE++ + QCW+ P ERP+F+ +++ L E T
Sbjct: 1043 TCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKT- 1101
Query: 706 NLSFTHYNGFEF 717
++ T Y F +
Sbjct: 1102 YVNTTLYEKFTY 1113
Score = 36.7 bits (81), Expect = 0.29
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 111 VAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYVIRAAVIETYSDYNLKPLEWRVSNE 170
+ P QP N+ + N T ++ + W+ + YS I+S IR V D + ++ ++ N
Sbjct: 637 ILPPQPENIKISNITHSSAVISWTILDGYS-ISSITIRYKVQGKNEDQH---VDVKIKNA 692
Query: 171 T-LNMELLNLHPGSKYNISVAALN 193
T + +L L P + Y + + A N
Sbjct: 693 TIIQYQLKGLEPETAYQVDIFAEN 716
>AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 144 bits (349), Expect = 1e-33
Identities = 79/252 (31%), Positives = 133/252 (52%), Gaps = 12/252 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRD- 534
K + + EL++L K H N+I+L+G CE L + +E L + L SR +
Sbjct: 863 KDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLET 922
Query: 535 -----IQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
I N+ +++ ++L VARGM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 923 DPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIAD 982
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS + ++ RW + E L + Y +DVWS+GVL+WE+++LG TPY
Sbjct: 983 FGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGM 1042
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTR 705
++ ++ +G R +P DE++ + QCW+ P ERP+F+ +++ L E T
Sbjct: 1043 TCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKT- 1101
Query: 706 NLSFTHYNGFEF 717
++ T Y F +
Sbjct: 1102 YVNTTLYEKFTY 1113
Score = 37.1 bits (82), Expect = 0.22
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 111 VAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYVIRAAVIETYSDYNLKPLEWRVSNE 170
+ P QP N+ + N T ++ + W+ + YS I+S IR V D + ++ ++ N
Sbjct: 637 ILPPQPENIKISNITHSSAVISWTILDGYS-ISSITIRYKVQGKNEDQH---VDVKIKNA 692
Query: 171 TLNM-ELLNLHPGSKYNISVAALN 193
T+ +L L P + Y + + A N
Sbjct: 693 TITQYQLKGLEPETAYQVDIFAEN 716
>AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase variant
protein.
Length = 1157
Score = 144 bits (349), Expect = 1e-33
Identities = 79/252 (31%), Positives = 133/252 (52%), Gaps = 12/252 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRD- 534
K + + EL++L K H N+I+L+G CE L + +E L + L SR +
Sbjct: 896 KDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLET 955
Query: 535 -----IQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
I N+ +++ ++L VARGM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 956 DPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIAD 1015
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS + ++ RW + E L + Y +DVWS+GVL+WE+++LG TPY
Sbjct: 1016 FGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGM 1075
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTR 705
++ ++ +G R +P DE++ + QCW+ P ERP+F+ +++ L E T
Sbjct: 1076 TCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKT- 1134
Query: 706 NLSFTHYNGFEF 717
++ T Y F +
Sbjct: 1135 YVNTTLYEKFTY 1146
Score = 37.1 bits (82), Expect = 0.22
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 111 VAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYVIRAAVIETYSDYNLKPLEWRVSNE 170
+ P QP N+ + N T ++ + W+ + YS I+S IR V D + ++ ++ N
Sbjct: 670 ILPPQPENIKISNITHSSAVISWTILDGYS-ISSITIRYKVQGKNEDQH---VDVKIKNA 725
Query: 171 TLNM-ELLNLHPGSKYNISVAALN 193
T+ +L L P + Y + + A N
Sbjct: 726 TITQYQLKGLEPETAYQVDIFAEN 749
>BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 144 bits (348), Expect = 1e-33
Identities = 79/252 (31%), Positives = 133/252 (52%), Gaps = 12/252 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRD- 534
K + + EL++L K H N+I+L+G CE L + +E L + L SR +
Sbjct: 863 KDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLET 922
Query: 535 -----IQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
I N+ +++ + +L VARGM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 923 DPAFAIANSTASTLSSHHLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIAD 982
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS + ++ RW + E L + Y +DVWS+GVL+WE+++LG TPY
Sbjct: 983 FGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGM 1042
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTR 705
++ ++ +G R +P DE++ + QCW+ P ERP+F+ +++ L E T
Sbjct: 1043 TCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKT- 1101
Query: 706 NLSFTHYNGFEF 717
++ T Y F +
Sbjct: 1102 YVNTTLYEKFTY 1113
Score = 37.1 bits (82), Expect = 0.22
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 111 VAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYVIRAAVIETYSDYNLKPLEWRVSNE 170
+ P QP N+ + N T ++ + W+ + YS I+S IR V D + ++ ++ N
Sbjct: 637 ILPPQPENIKISNITHSSAVISWTILDGYS-ISSITIRYKVQGKNEDQH---VDVKIKNA 692
Query: 171 TLNM-ELLNLHPGSKYNISVAALN 193
T+ +L L P + Y + + A N
Sbjct: 693 TITQYQLKGLEPETAYQVDIFAEN 716
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 319 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 378
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 379 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 438
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 439 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 496
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 497 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 554
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 428 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 487
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 488 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 547
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 548 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 605
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 606 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 663
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 430 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 489
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 490 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 549
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 550 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 607
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 608 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 665
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 428 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 487
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 488 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 547
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 548 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 605
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 606 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 663
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 428 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 487
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 488 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 547
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 548 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 605
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 606 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 663
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 430 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 489
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 490 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 549
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 550 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 607
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 608 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 665
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 428 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 487
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 488 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 547
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 548 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 605
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 606 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 663
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 519 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 578
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 579 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 638
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 639 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 696
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 697 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 754
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 141 bits (342), Expect = 7e-33
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 511 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 570
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 571 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 630
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 631 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 688
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 689 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 746
>AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth factor
receptor 1 isoform 2 precursor variant protein.
Length = 820
Score = 140 bits (340), Expect = 1e-32
Identities = 78/238 (32%), Positives = 130/238 (54%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ 532
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 517 DATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQAWRP 576
Query: 533 RDIQ------NNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
++ +N ++ ++ QVARGMEYL ++K +H+ L RN++++E+ +K
Sbjct: 577 PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMK 636
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R +H Y +W + E L Y ++DVWSFGVL+WE+ TL
Sbjct: 637 IADFGLA--RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 694
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +PS +EL+ + CW P +RPTF LV +L
Sbjct: 695 GGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 752
>X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA for
receptor-related tyrosine kinase. ).
Length = 1338
Score = 140 bits (338), Expect = 2e-32
Identities = 70/169 (41%), Positives = 101/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+++SEN VKI FGL+ R +++ P
Sbjct: 994 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA--RDIYKNP 1051
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 1052 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 1111
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 1112 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160
>AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine kinase
1 (vascular endothelial growth factor/vascular perm
protein.
Length = 1338
Score = 140 bits (338), Expect = 2e-32
Identities = 70/169 (41%), Positives = 101/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+++SEN VKI FGL+ R +++ P
Sbjct: 994 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA--RDIYKNP 1051
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 1052 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 1111
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 1112 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160
>AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine kinase
1 (vascular endothelial growth factor/vascular perm
protein.
Length = 1338
Score = 140 bits (338), Expect = 2e-32
Identities = 70/169 (41%), Positives = 101/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+++SEN VKI FGL+ R +++ P
Sbjct: 994 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA--RDIYKNP 1051
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 1052 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 1111
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 1112 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160
>AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial growth
factor receptor protein.
Length = 1338
Score = 140 bits (338), Expect = 2e-32
Identities = 70/169 (41%), Positives = 101/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+++SEN VKI FGL+ R +++ P
Sbjct: 994 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA--RDIYKNP 1051
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 1052 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 1111
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 1112 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160
>AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine
kinase 1 (vascular endothelial growth factor/vascular
perm protein.
Length = 551
Score = 140 bits (338), Expect = 2e-32
Identities = 70/169 (41%), Positives = 101/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+++SEN VKI FGL+ R +++ P
Sbjct: 207 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA--RDIYKNP 264
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 265 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 324
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 325 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 373
>X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein.
Length = 1400
Score = 139 bits (336), Expect = 4e-32
Identities = 96/275 (34%), Positives = 132/275 (48%), Gaps = 17/275 (6%)
Query: 430 IPRNLIETDISCVVGVGTYXXXXXXXXXXXXXXXXXXXXXIADRELEKTEKKQMLQELDL 489
IP + T V+G G + R E + + L+E L
Sbjct: 1075 IPHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLRE-GL 1133
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
L++ H NV++LIGI L VL + LL R Q N T ++
Sbjct: 1134 LMRGLNHPNVLALIGIMLPPEGLPHVLLPY---MCHGDLLQFIRSPQRNP----TVKDLI 1186
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---RSLHETPDY-- 604
+QVARGMEYL +K VH+ L RN ++ E+ TVK+A FGL+ R + +
Sbjct: 1187 SFGLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRH 1246
Query: 605 ----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+W + E L+ R+ K+DVWSFGVL+WE+LT GA PY H D+ + +G R
Sbjct: 1247 ARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRL 1306
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
QP Y D L+QV QCW+ DP RPTF LV E+
Sbjct: 1307 PQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEV 1341
>DQ836395-1|ABI53804.1| 556|Homo sapiens N2idVEGFR-1 protein.
Length = 556
Score = 139 bits (336), Expect = 4e-32
Identities = 70/169 (41%), Positives = 100/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+ +SEN VKI FGL+ R +++ P
Sbjct: 212 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNIFLSENNVVKICDFGLA--RDIYKNP 269
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 270 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 329
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 330 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 378
>DQ836394-1|ABI53803.1| 556|Homo sapiens idVEGFR-1 protein.
Length = 556
Score = 139 bits (336), Expect = 4e-32
Identities = 70/169 (41%), Positives = 100/169 (59%), Gaps = 12/169 (7%)
Query: 543 ITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETP 602
IT ++ QVARGME+L +RK +H+ L RN+ +SEN VKI FGL+ R +++ P
Sbjct: 212 ITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNIFLSENNVVKICDFGLA--RDIYKNP 269
Query: 603 DYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGS 652
DY R W + E + Y+ K+DVWS+GVL+WE+ +LG +PY ++D S
Sbjct: 270 DYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCS 329
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
R+ GMR P Y E++Q+ L CW DP ERP F+ LV +L +A
Sbjct: 330 RLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 378
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 138 bits (335), Expect = 5e-32
Identities = 73/236 (30%), Positives = 125/236 (52%), Gaps = 11/236 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDI 535
+ + + EL++L K H N+I+L+G C+ L + +E L + L SR +
Sbjct: 878 ENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLET 937
Query: 536 ------QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
++ +++ ++L+ A GM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 938 DPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIAD 997
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS ++ RW + E L + Y K+DVWSFGVL+WE+++LG TPY
Sbjct: 998 FGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGM 1057
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
++ ++ +G R QP DE++++ QCW+ P ERP F+ + ++L EA
Sbjct: 1058 TCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEA 1113
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 138 bits (335), Expect = 5e-32
Identities = 73/236 (30%), Positives = 125/236 (52%), Gaps = 11/236 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDI 535
+ + + EL++L K H N+I+L+G C+ L + +E L + L SR +
Sbjct: 878 ENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLET 937
Query: 536 ------QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
++ +++ ++L+ A GM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 938 DPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIAD 997
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS ++ RW + E L + Y K+DVWSFGVL+WE+++LG TPY
Sbjct: 998 FGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGM 1057
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
++ ++ +G R QP DE++++ QCW+ P ERP F+ + ++L EA
Sbjct: 1058 TCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEA 1113
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 138 bits (335), Expect = 5e-32
Identities = 73/236 (30%), Positives = 125/236 (52%), Gaps = 11/236 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDI 535
+ + + EL++L K H N+I+L+G C+ L + +E L + L SR +
Sbjct: 878 ENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLET 937
Query: 536 ------QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
++ +++ ++L+ A GM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 938 DPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIAD 997
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS ++ RW + E L + Y K+DVWSFGVL+WE+++LG TPY
Sbjct: 998 FGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGM 1057
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
++ ++ +G R QP DE++++ QCW+ P ERP F+ + ++L EA
Sbjct: 1058 TCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEA 1113
>AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 541
Score = 138 bits (335), Expect = 5e-32
Identities = 73/236 (30%), Positives = 125/236 (52%), Gaps = 11/236 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDI 535
+ + + EL++L K H N+I+L+G C+ L + +E L + L SR +
Sbjct: 281 ENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLET 340
Query: 536 ------QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
++ +++ ++L+ A GM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 341 DPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIAD 400
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS ++ RW + E L + Y K+DVWSFGVL+WE+++LG TPY
Sbjct: 401 FGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGM 460
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
++ ++ +G R QP DE++++ QCW+ P ERP F+ + ++L EA
Sbjct: 461 TCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEA 516
>AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein.
Length = 421
Score = 138 bits (335), Expect = 5e-32
Identities = 73/236 (30%), Positives = 125/236 (52%), Gaps = 11/236 (4%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDI 535
+ + + EL++L K H N+I+L+G C+ L + +E L + L SR +
Sbjct: 161 ENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLET 220
Query: 536 ------QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
++ +++ ++L+ A GM+YL ++ +H+ L RN+++ EN KIA
Sbjct: 221 DPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIAD 280
Query: 590 FGLSHLRSLHETPDY----TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
FGLS ++ RW + E L + Y K+DVWSFGVL+WE+++LG TPY
Sbjct: 281 FGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGM 340
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
++ ++ +G R QP DE++++ QCW+ P ERP F+ + ++L EA
Sbjct: 341 TCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEA 396
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 138 bits (333), Expect = 9e-32
Identities = 82/230 (35%), Positives = 128/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 253 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 303
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+GM+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 304 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 361
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGVL+WE++T GA PY
Sbjct: 362 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVN 421
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 422 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 471
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 138 bits (333), Expect = 9e-32
Identities = 82/230 (35%), Positives = 128/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 185 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 235
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+GM+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 236 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 293
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGVL+WE++T GA PY
Sbjct: 294 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVN 353
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 354 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 403
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 138 bits (333), Expect = 9e-32
Identities = 80/250 (32%), Positives = 131/250 (52%), Gaps = 20/250 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 432 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 491
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 492 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 551
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 552 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 609
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTP 697
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 610 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 669
Query: 698 FSEAPGTRNL 707
P ++
Sbjct: 670 IPPNPSLMSI 679
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 138 bits (333), Expect = 9e-32
Identities = 82/230 (35%), Positives = 128/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 1120 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 1170
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+GM+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 1171 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 1228
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGVL+WE++T GA PY
Sbjct: 1229 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVN 1288
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 1289 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 1338
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene
precursor variant protein.
Length = 712
Score = 138 bits (333), Expect = 9e-32
Identities = 82/230 (35%), Positives = 128/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 442 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 492
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+GM+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 493 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 550
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGVL+WE++T GA PY
Sbjct: 551 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVN 610
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 611 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 660
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 522 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 581
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 582 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 641
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 642 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 699
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 700 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 757
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 522 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 581
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 582 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 641
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 642 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 699
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 700 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 757
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 406 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 465
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 466 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 525
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 526 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 583
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 584 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 641
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 522 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 581
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 582 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 641
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 642 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 699
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 700 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 757
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 520 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 579
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 580 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 639
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 640 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 697
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 698 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 755
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 405 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 464
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 465 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 524
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 525 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 582
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 583 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 640
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 520 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 579
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 580 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 639
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 640 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 697
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 698 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 755
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 520 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 579
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 580 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 639
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 640 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 697
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 698 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 755
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 520 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 579
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 580 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 639
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 640 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 697
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 698 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 755
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 521 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 580
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 581 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 640
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 641 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 698
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 699 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 756
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 309 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 368
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 369 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 428
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 429 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 486
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 487 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 544
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor
2 IgIIIb isoform protein.
Length = 555
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 310 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 369
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 370 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 429
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 430 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 487
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 488 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 545
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 410 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 469
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+ARGMEYL ++K +H+ L RN++++EN +K
Sbjct: 470 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 529
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 530 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 587
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 588 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 645
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 136 bits (330), Expect = 2e-31
Identities = 81/230 (35%), Positives = 128/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 1120 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 1170
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+GM+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 1171 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 1228
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGV++WE++T GA PY
Sbjct: 1229 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVN 1288
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 1289 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 1338
>M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein.
Length = 731
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 447 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 506
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 507 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 564
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 565 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 624
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 625 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 673
>M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor
receptor protein.
Length = 806
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 522 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 581
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 582 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 639
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 640 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 699
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 700 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 748
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 135 bits (326), Expect = 6e-31
Identities = 71/231 (30%), Positives = 123/231 (53%), Gaps = 19/231 (8%)
Query: 474 ELEKTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQR 533
+L + K + LQE +L K +H N++ LIG+C + +++E + + L R++
Sbjct: 596 DLPQELKIKFLQEAKIL-KQYDHPNIVKLIGVCTQRQPVYIIMELVSGG-DFLTFLRRKK 653
Query: 534 DIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS 593
D + ++++ + A GM YL ++ +H+ L RN ++ EN +KI+ FG+S
Sbjct: 654 D-------ELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMS 706
Query: 594 HLRS--------LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
L + P +WT+ E L RY+ ++DVWSFG+L+WE +LG PY
Sbjct: 707 RQEDGGVYSSSGLKQIP--IKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGM 764
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
N+ ++ RG R S P + +++ ++ ++CW P+ RP FS L ELT
Sbjct: 765 TNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELT 815
>BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 196 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 255
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 256 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 313
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 314 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 373
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 374 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 422
>BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 196 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 255
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 256 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 313
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 314 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 373
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 374 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 422
>AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth factor
receptor 3 (achondroplasia, thanatophoric dwarfism)
protein.
Length = 806
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 522 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 581
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 582 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 639
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 640 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 699
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 700 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 748
>AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 769
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 485 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 544
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 545 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 602
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 603 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 662
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 663 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 711
>AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 771
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 487 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 546
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 547 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 604
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 605 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 664
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 665 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 713
>AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 694
Score = 135 bits (326), Expect = 6e-31
Identities = 76/229 (33%), Positives = 125/229 (54%), Gaps = 18/229 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQRDIQNN-KF 540
++ E++++ +H+N+I+L+G C L V++E K L+E L R + +
Sbjct: 410 LVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDT 469
Query: 541 CSITENKV----LQICV-QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
C E ++ L C QVARGMEYL ++K +H+ L RN++++E+ +KIA FGL+
Sbjct: 470 CKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLA-- 527
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFGVL+WE+ TLG +PY
Sbjct: 528 RDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP 587
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+++ + G R +P+ +L+ + +CW P +RPTF LV +L
Sbjct: 588 VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 636
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 517 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 576
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 577 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 634
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 635 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 694
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 695 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 740
>AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth factor
receptor 4 variant protein.
Length = 592
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 307 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 366
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 367 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 424
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 425 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 484
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 485 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 530
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 477 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 536
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 537 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 594
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 595 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 654
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 655 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 700
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 134 bits (325), Expect = 8e-31
Identities = 73/226 (32%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Query: 483 MLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR------QRDI 535
++ E++++ H+N+I+L+G+C L V++E K L+E L R D
Sbjct: 749 LVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDG 808
Query: 536 QNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL 595
+ ++ ++ QVARGM+YL +RK +H+ L RN++++E+ +KIA FGL+
Sbjct: 809 PRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA-- 866
Query: 596 RSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
R +H Y +W + E L Y ++DVWSFG+L+WE+ TLG +PY
Sbjct: 867 RGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 926
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+++ S + G R +P + EL+ + +CW P +RPTF LV
Sbjct: 927 VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV 972
>M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth factor
receptor protein.
Length = 822
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 134 bits (324), Expect = 1e-30
Identities = 80/230 (34%), Positives = 127/230 (55%), Gaps = 23/230 (10%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIKKTLKEMLLLSRQRDIQN 537
E Q L E +++K H NV+SL+GIC + + LVVL +K R+
Sbjct: 1138 EVSQFLTE-GIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKH--------GDLRNFIR 1188
Query: 538 NKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
N+ + T ++ +QVA+ M+YL ++K VH+ L RN ++ E TVK+A FGL+ R
Sbjct: 1189 NETHNPTVKDLIGFGLQVAKAMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA--RD 1246
Query: 598 LHETPDYT-----------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSG 646
+++ Y+ +W + E L+ ++ K+DVWSFGV++WE++T GA PY
Sbjct: 1247 MYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVN 1306
Query: 647 NKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELT 696
D+ +L+G R QP Y D L++V L+CW + RP+FS LV ++
Sbjct: 1307 TFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRIS 1356
>AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein.
Length = 768
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein.
Length = 817
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein.
Length = 771
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein.
Length = 830
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein.
Length = 819
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein.
Length = 819
Score = 134 bits (324), Expect = 1e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 20/238 (8%)
Query: 476 EKTEK--KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSR- 531
+ TEK ++ E++++ +H+N+I+L+G C + L V++E K L+E L R
Sbjct: 523 DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP 582
Query: 532 -----QRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
DI +T ++ Q+AR MEYL ++K +H+ L RN++++EN +K
Sbjct: 583 PGMEYSYDINRVPEEQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMK 642
Query: 587 IAGFGLSHLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTL 637
IA FGL+ R ++ Y +W + E L Y ++DVWSFGVLMWE+ TL
Sbjct: 643 IADFGLA--RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 700
Query: 638 GATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
G +PY +++ + G R +P+ +EL+ + CW P +RPTF LV +L
Sbjct: 701 GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 758
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 132 bits (320), Expect = 3e-30
Identities = 76/241 (31%), Positives = 130/241 (53%), Gaps = 14/241 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + + H +V+ L+G+ LV++E + + + L S + +++NN
Sbjct: 1043 ERIEFLNEASVMKEFNCH-HVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN 1101
Query: 539 KFCSITE-NKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
+ +K++Q+ ++A GM YL+ K VH+ L RN +++E+ TVKI FG++ R
Sbjct: 1102 PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMT--RD 1159
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW S E L+ + +DVWSFGV++WE+ TL PY N+
Sbjct: 1160 IYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNE 1219
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G +P D LF++ CWQ +P RP+F ++ + E PG R +S
Sbjct: 1220 QVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEME-PGFREVS 1278
Query: 709 F 709
F
Sbjct: 1279 F 1279
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 132 bits (320), Expect = 3e-30
Identities = 76/241 (31%), Positives = 130/241 (53%), Gaps = 14/241 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + + H +V+ L+G+ LV++E + + + L S + +++NN
Sbjct: 1043 ERIEFLNEASVMKEFNCH-HVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN 1101
Query: 539 KFCSITE-NKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
+ +K++Q+ ++A GM YL+ K VH+ L RN +++E+ TVKI FG++ R
Sbjct: 1102 PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMT--RD 1159
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW S E L+ + +DVWSFGV++WE+ TL PY N+
Sbjct: 1160 IYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNE 1219
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G +P D LF++ CWQ +P RP+F ++ + E PG R +S
Sbjct: 1220 QVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEME-PGFREVS 1278
Query: 709 F 709
F
Sbjct: 1279 F 1279
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 132 bits (320), Expect = 3e-30
Identities = 76/241 (31%), Positives = 130/241 (53%), Gaps = 14/241 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + + H +V+ L+G+ LV++E + + + L S + +++NN
Sbjct: 1043 ERIEFLNEASVMKEFNCH-HVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN 1101
Query: 539 KFCSITE-NKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
+ +K++Q+ ++A GM YL+ K VH+ L RN +++E+ TVKI FG++ R
Sbjct: 1102 PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMT--RD 1159
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW S E L+ + +DVWSFGV++WE+ TL PY N+
Sbjct: 1160 IYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNE 1219
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G +P D LF++ CWQ +P RP+F ++ + E PG R +S
Sbjct: 1220 QVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEME-PGFREVS 1278
Query: 709 F 709
F
Sbjct: 1279 F 1279
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 132 bits (320), Expect = 3e-30
Identities = 76/241 (31%), Positives = 130/241 (53%), Gaps = 14/241 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + + H +V+ L+G+ LV++E + + + L S + +++NN
Sbjct: 1043 ERIEFLNEASVMKEFNCH-HVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN 1101
Query: 539 KFCSITE-NKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
+ +K++Q+ ++A GM YL+ K VH+ L RN +++E+ TVKI FG++ R
Sbjct: 1102 PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMT--RD 1159
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW S E L+ + +DVWSFGV++WE+ TL PY N+
Sbjct: 1160 IYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNE 1219
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G +P D LF++ CWQ +P RP+F ++ + E PG R +S
Sbjct: 1220 QVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEME-PGFREVS 1278
Query: 709 F 709
F
Sbjct: 1279 F 1279
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 130 bits (315), Expect = 1e-29
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 15/228 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E ++++K S H ++ L G+C + +V E E LS Q
Sbjct: 400 EEDFIEEAEVMMKLS-HPKLVQLYGVCLEQAPICLVFE-----FMEHGCLSDYLRTQRGL 453
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
F + T +L +C+ V GM YL ++H+ L RN ++ EN +K++ FG++
Sbjct: 454 FAAET---LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD 510
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S T +W S E+ +RY+ K+DVWSFGVLMWEV + G PY + N +V
Sbjct: 511 QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVED 570
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
I G R +P ++Q+ CW+ P++RP FS L+ +L +E+
Sbjct: 571 ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 130 bits (315), Expect = 1e-29
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 15/228 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E ++++K S H ++ L G+C + +V E E LS Q
Sbjct: 400 EEDFIEEAEVMMKLS-HPKLVQLYGVCLEQAPICLVFE-----FMEHGCLSDYLRTQRGL 453
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
F + T +L +C+ V GM YL ++H+ L RN ++ EN +K++ FG++
Sbjct: 454 FAAET---LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD 510
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S T +W S E+ +RY+ K+DVWSFGVLMWEV + G PY + N +V
Sbjct: 511 QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVED 570
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
I G R +P ++Q+ CW+ P++RP FS L+ +L +E+
Sbjct: 571 ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 130 bits (315), Expect = 1e-29
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 15/228 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E ++++K S H ++ L G+C + +V E E LS Q
Sbjct: 400 EEDFIEEAEVMMKLS-HPKLVQLYGVCLEQAPICLVFE-----FMEHGCLSDYLRTQRGL 453
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
F + T +L +C+ V GM YL ++H+ L RN ++ EN +K++ FG++
Sbjct: 454 FAAET---LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD 510
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S T +W S E+ +RY+ K+DVWSFGVLMWEV + G PY + N +V
Sbjct: 511 QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVED 570
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
I G R +P ++Q+ CW+ P++RP FS L+ +L +E+
Sbjct: 571 ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 130 bits (315), Expect = 1e-29
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 15/228 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E ++++K S H ++ L G+C + +V E E LS Q
Sbjct: 400 EEDFIEEAEVMMKLS-HPKLVQLYGVCLEQAPICLVFE-----FMEHGCLSDYLRTQRGL 453
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
F + T +L +C+ V GM YL ++H+ L RN ++ EN +K++ FG++
Sbjct: 454 FAAET---LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD 510
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S T +W S E+ +RY+ K+DVWSFGVLMWEV + G PY + N +V
Sbjct: 511 QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVED 570
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
I G R +P ++Q+ CW+ P++RP FS L+ +L +E+
Sbjct: 571 ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 130 bits (315), Expect = 1e-29
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 15/228 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E ++++K S H ++ L G+C + +V E E LS Q
Sbjct: 400 EEDFIEEAEVMMKLS-HPKLVQLYGVCLEQAPICLVFE-----FMEHGCLSDYLRTQRGL 453
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
F + T +L +C+ V GM YL ++H+ L RN ++ EN +K++ FG++
Sbjct: 454 FAAET---LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD 510
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S T +W S E+ +RY+ K+DVWSFGVLMWEV + G PY + N +V
Sbjct: 511 QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVED 570
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA 701
I G R +P ++Q+ CW+ P++RP FS L+ +L +E+
Sbjct: 571 ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 130 bits (314), Expect = 2e-29
Identities = 72/225 (32%), Positives = 120/225 (53%), Gaps = 20/225 (8%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 601 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 654
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 655 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 711
Query: 598 -------LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDV 650
L + P +WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 712 VYAASGGLRQVP--VKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQT 769
Query: 651 GSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 770 REFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 814
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 130 bits (314), Expect = 2e-29
Identities = 72/225 (32%), Positives = 120/225 (53%), Gaps = 20/225 (8%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 601 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 654
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 655 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 711
Query: 598 -------LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDV 650
L + P +WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 712 VYAASGGLRQVP--VKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQT 769
Query: 651 GSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 770 REFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 814
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 130 bits (313), Expect = 2e-29
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
++K H +I L +C + ++ E ++ S Q +QN+ I + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG-------SLQEYLQNDTGSKIHLTQQV 332
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---------RSLHE 600
+ QVA GM YL +R +H+ L RN+++ E+ K+A FGL+ + S HE
Sbjct: 333 DMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE 392
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+WT+ E +R +++ K+DVWSFG+L++E++T G PYS V + + R
Sbjct: 393 IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRL 452
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
QPS + + + L+CW +P ERPTF +L +L + E
Sbjct: 453 PQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFE 492
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 130 bits (313), Expect = 2e-29
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
++K H +I L +C + ++ E ++ S Q +QN+ I + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG-------SLQEYLQNDTGSKIHLTQQV 332
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---------RSLHE 600
+ QVA GM YL +R +H+ L RN+++ E+ K+A FGL+ + S HE
Sbjct: 333 DMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE 392
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+WT+ E +R +++ K+DVWSFG+L++E++T G PYS V + + R
Sbjct: 393 IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRL 452
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
QPS + + + L+CW +P ERPTF +L +L + E
Sbjct: 453 PQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFE 492
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 130 bits (313), Expect = 2e-29
Identities = 71/231 (30%), Positives = 120/231 (51%), Gaps = 15/231 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E +++K + H ++ L G+C + +V E +++ +L RQR Q +
Sbjct: 407 EEDFIEEAKVMMKLT-HPKLVQLYGVCTQQKPIYIVTEFMERGC--LLNFLRQR--QGH- 460
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
+ + +L +C V GMEYL +H+ L RN ++SE G VK++ FG++
Sbjct: 461 ---FSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYFLDD 517
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S +W E+ +R++ K+DVWSFGVLMWEV T G P+ N +V +
Sbjct: 518 QYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTM 577
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGT 704
+ RG R QP + +++V L+CWQ P+ RP+F L+ + E T
Sbjct: 578 VTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEET 628
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 130 bits (313), Expect = 2e-29
Identities = 71/231 (30%), Positives = 120/231 (51%), Gaps = 15/231 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E +++K + H ++ L G+C + +V E +++ +L RQR Q +
Sbjct: 407 EEDFIEEAKVMMKLT-HPKLVQLYGVCTQQKPIYIVTEFMERGC--LLNFLRQR--QGH- 460
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
+ + +L +C V GMEYL +H+ L RN ++SE G VK++ FG++
Sbjct: 461 ---FSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDD 517
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S +W E+ +R++ K+DVWSFGVLMWEV T G P+ N +V +
Sbjct: 518 QYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTM 577
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGT 704
+ RG R QP + +++V L+CWQ P+ RP+F L+ + E T
Sbjct: 578 VTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEET 628
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 130 bits (313), Expect = 2e-29
Identities = 71/231 (30%), Positives = 120/231 (51%), Gaps = 15/231 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E +++K + H ++ L G+C + +V E +++ +L RQR Q +
Sbjct: 407 EEDFIEEAKVMMKLT-HPKLVQLYGVCTQQKPIYIVTEFMERGC--LLNFLRQR--QGH- 460
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---- 595
+ + +L +C V GMEYL +H+ L RN ++SE G VK++ FG++
Sbjct: 461 ---FSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDD 517
Query: 596 --RSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
S +W E+ +R++ K+DVWSFGVLMWEV T G P+ N +V +
Sbjct: 518 QYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTM 577
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGT 704
+ RG R QP + +++V L+CWQ P+ RP+F L+ + E T
Sbjct: 578 VTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEET 628
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 130 bits (313), Expect = 2e-29
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
++K H +I L +C + ++ E ++ S Q +QN+ I + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG-------SLQEYLQNDTGSKIHLTQQV 332
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---------RSLHE 600
+ QVA GM YL +R +H+ L RN+++ E+ K+A FGL+ + S HE
Sbjct: 333 DMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE 392
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+WT+ E +R +++ K+DVWSFG+L++E++T G PYS V + + R
Sbjct: 393 IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRL 452
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
QPS + + + L+CW +P ERPTF +L +L + E
Sbjct: 453 PQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFE 492
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 130 bits (313), Expect = 2e-29
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
++K H +I L +C + ++ E ++ S Q +QN+ I + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG-------SLQEYLQNDTGSKIHLTQQV 332
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---------RSLHE 600
+ QVA GM YL +R +H+ L RN+++ E+ K+A FGL+ + S HE
Sbjct: 333 DMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE 392
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+WT+ E +R +++ K+DVWSFG+L++E++T G PYS V + + R
Sbjct: 393 IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRL 452
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
QPS + + + L+CW +P ERPTF +L +L + E
Sbjct: 453 PQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFE 492
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 130 bits (313), Expect = 2e-29
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 490 LIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVL 549
++K H +I L +C + ++ E ++ S Q +QN+ I + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG-------SLQEYLQNDTGSKIHLTQQV 332
Query: 550 QICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL---------RSLHE 600
+ QVA GM YL +R +H+ L RN+++ E+ K+A FGL+ + S HE
Sbjct: 333 DMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHE 392
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+WT+ E +R +++ K+DVWSFG+L++E++T G PYS V + + R
Sbjct: 393 IKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRL 452
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
QPS + + + L+CW +P ERPTF +L +L + E
Sbjct: 453 PQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFE 492
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 129 bits (312), Expect = 3e-29
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 444
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 445 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 129 bits (312), Expect = 3e-29
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 444
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 445 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 129 bits (312), Expect = 3e-29
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 444
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 445 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 129 bits (312), Expect = 3e-29
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 444
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 445 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 129 bits (312), Expect = 3e-29
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 444
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 445 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 439 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 490
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 491 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 549
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 550 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 609
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 610 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 646
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 129 bits (311), Expect = 4e-29
Identities = 62/217 (28%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ ++E +++ S HE ++ L G+C + ++ E + LL+ R++++
Sbjct: 441 EFIEEAKVMMNLS-HEKLVQLYGVCTKQRPIFIITE----YMANGCLLNYLREMRHR--- 492
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHET 601
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 493 -FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEY 551
Query: 602 PDYT------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I
Sbjct: 552 TSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIA 611
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+G+R +P ++++ + CW DERPTF L+
Sbjct: 612 QGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILL 648
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 128 bits (310), Expect = 5e-29
Identities = 71/223 (31%), Positives = 120/223 (53%), Gaps = 16/223 (7%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 601 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 654
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 655 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 711
Query: 598 LHETPDYTR-----WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
++ +R WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 712 VYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 771
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 772 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 814
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 128 bits (310), Expect = 5e-29
Identities = 71/223 (31%), Positives = 120/223 (53%), Gaps = 16/223 (7%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 531 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 584
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 585 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 641
Query: 598 LHETPDYTR-----WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
++ +R WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 642 VYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 701
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 702 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 744
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 128 bits (310), Expect = 5e-29
Identities = 71/223 (31%), Positives = 120/223 (53%), Gaps = 16/223 (7%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 543 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 596
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 597 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 653
Query: 598 LHETPDYTR-----WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
++ +R WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 654 VYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 713
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 714 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 756
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 128 bits (310), Expect = 5e-29
Identities = 71/223 (31%), Positives = 120/223 (53%), Gaps = 16/223 (7%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
K + LQE +L K H N++ LIG+C + +V+E ++ + L R +
Sbjct: 473 KAKFLQEARIL-KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR--- 526
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS-- 597
+ +LQ+ A GMEYL ++ +H+ L RN +++E +KI+ FG+S +
Sbjct: 527 ---LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADG 583
Query: 598 LHETPDYTR-----WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
++ +R WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+
Sbjct: 584 VYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 643
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ +G R P D +F++ QCW +P +RP+FS++ EL
Sbjct: 644 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 686
>X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret
proto-oncogene mRNA for tyrosine kinase. ).
Length = 860
Score = 128 bits (309), Expect = 7e-29
Identities = 91/336 (27%), Positives = 161/336 (47%), Gaps = 34/336 (10%)
Query: 387 QRGSQSMPLSLSEPCVEIENSGFILEDEERVDYYGNLKRKLWNIPR-NLIETDISCVVGV 445
+R +Q+ P+S S S +E++ VD + L+ W PR NL+ + +G
Sbjct: 423 RRPAQAFPVSYSSSGAR-RPSLDSMENQVSVDAFKILEDPKWEFPRKNLV---LGKTLGE 478
Query: 446 GTYXXXXXXXXXXXXXXXXXXXXXIA--DRELEKTEKKQMLQELDLLIKTSEHENVISLI 503
G + + +E + +L E ++L K H +VI L
Sbjct: 479 GEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVIKLY 537
Query: 504 GICETNTTLLVVLEDIKK-TLKEMLLLSRQ--------------RDIQNNKFCSITENKV 548
G C + LL+++E K +L+ L SR+ + + ++T +
Sbjct: 538 GACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDL 597
Query: 549 LQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR-- 606
+ Q+++GM+YL K+VH+ L RN++++E +KI+ FGLS R ++E Y +
Sbjct: 598 ISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS--RDVYEEDSYVKRS 655
Query: 607 -------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMR 659
W + E L Y ++DVWSFGVL+WE++TLG PY + + + + G R
Sbjct: 656 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 715
Query: 660 PSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+P +E++++ LQCW+ +PD+RP F+ + +L
Sbjct: 716 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDL 751
>M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA
encoding a tyrosine kinase, partial cds. ).
Length = 805
Score = 128 bits (308), Expect = 9e-29
Identities = 91/336 (27%), Positives = 161/336 (47%), Gaps = 34/336 (10%)
Query: 387 QRGSQSMPLSLSEPCVEIENSGFILEDEERVDYYGNLKRKLWNIPR-NLIETDISCVVGV 445
+R +Q+ P+S S S +E++ VD + L+ W PR NL+ + +G
Sbjct: 410 RRPAQAFPVSYSSSGAR-RPSLDSMENQVSVDAFKILEDPKWEFPRKNLV---LGKTLGE 465
Query: 446 GTYXXXXXXXXXXXXXXXXXXXXXIA--DRELEKTEKKQMLQELDLLIKTSEHENVISLI 503
G + + +E + +L E ++L K H +VI L
Sbjct: 466 GEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVIKLY 524
Query: 504 GICETNTTLLVVLEDIKK-TLKEMLLLSRQ--------------RDIQNNKFCSITENKV 548
G C + LL+++E K +L+ L SR+ + + ++T +
Sbjct: 525 GACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDL 584
Query: 549 LQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR-- 606
+ Q+++GM+YL K+VH+ L RN++++E +KI+ FGLS R ++E Y +
Sbjct: 585 ISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS--RDVYEEDPYVKRS 642
Query: 607 -------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMR 659
W + E L Y ++DVWSFGVL+WE++TLG PY + + + + G R
Sbjct: 643 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 702
Query: 660 PSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+P +E++++ LQCW+ +PD+RP F+ + +L
Sbjct: 703 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDL 738
>X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor
receptor protein.
Length = 1210
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 742 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 796
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 797 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 852
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 853 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 912
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 913 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 972
Query: 700 EAP 702
P
Sbjct: 973 RDP 975
>BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein.
Length = 1091
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 697 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 751
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 752 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 807
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 808 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 867
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 868 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 927
Query: 700 EAP 702
P
Sbjct: 928 RDP 930
>BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene protein.
Length = 1072
Score = 127 bits (307), Expect = 1e-28
Identities = 91/336 (27%), Positives = 160/336 (47%), Gaps = 34/336 (10%)
Query: 387 QRGSQSMPLSLSEPCVEIENSGFILEDEERVDYYGNLKRKLWNIPR-NLIETDISCVVGV 445
+R +Q+ P+S S S +E++ VD + L+ W PR NL+ + +G
Sbjct: 677 RRPAQAFPVSYSSSSAR-RPSLDSMENQVSVDAFKILEDPKWEFPRKNLV---LGKTLGE 732
Query: 446 GTYXXXXXXXXXXXXXXXXXXXXXIA--DRELEKTEKKQMLQELDLLIKTSEHENVISLI 503
G + + +E + +L E ++L K H +VI L
Sbjct: 733 GEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVIKLY 791
Query: 504 GICETNTTLLVVLEDIKK-TLKEMLLLSRQ--------------RDIQNNKFCSITENKV 548
G C + LL+++E K +L+ L SR+ + + ++T +
Sbjct: 792 GACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDL 851
Query: 549 LQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR-- 606
+ Q+++GM+YL K+VH+ L RN++++E +KI+ FGLS R ++E Y +
Sbjct: 852 ISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS--RDVYEEDSYVKRS 909
Query: 607 -------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMR 659
W + E L Y ++DVWSFGVL+WE++TLG PY + + + + G R
Sbjct: 910 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 969
Query: 660 PSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+P +E++ + LQCW+ +PD+RP F+ + +L
Sbjct: 970 MERPDNCSEEMYCLMLQCWKQEPDKRPVFADISKDL 1005
>AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor
receptor (erythroblastic leukemia viral (v-erb-b) oncog
protein.
Length = 1210
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 742 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 796
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 797 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 852
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 853 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 912
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 913 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 972
Query: 700 EAP 702
P
Sbjct: 973 RDP 975
>AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting
protein 40 protein.
Length = 1210
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 742 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 796
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 797 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 852
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 853 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 912
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 913 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 972
Query: 700 EAP 702
P
Sbjct: 973 RDP 975
>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase
receptor protein.
Length = 1091
Score = 127 bits (307), Expect = 1e-28
Identities = 91/337 (27%), Positives = 161/337 (47%), Gaps = 35/337 (10%)
Query: 387 QRGSQSMPLSLSEPCVEIENSGFILEDEERVDYYGNLKRKLWNIPR-NLIETDISCVVGV 445
+R +Q+ P+S S S +E++ VD + L+ W PR NL+ + +G
Sbjct: 653 RRPAQAFPVSYSSSGAR-RPSLDSMENQVSVDAFKILEDPKWEFPRKNLV---LGKTLGE 708
Query: 446 GTYXXXXXXXXXXXXXXXXXXXXXIA--DRELEKTEKKQMLQELDLLIKTSEHENVISLI 503
G + + +E + +L E ++L K H +VI L
Sbjct: 709 GEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVIKLY 767
Query: 504 GICETNTTLLVVLEDIKK-TLKEMLLLSRQ--------------RDIQNNKFCSITENKV 548
G C + LL+++E K +L+ L SR+ + + ++T +
Sbjct: 768 GACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDL 827
Query: 549 LQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR-- 606
+ Q+++GM+YL K+VH+ L RN++++E +KI+ FGLS R ++E Y +
Sbjct: 828 ISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS--RDVYEEDSYVKRS 885
Query: 607 --------WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGM 658
W + E L Y ++DVWSFGVL+WE++TLG PY + + + + G
Sbjct: 886 QVGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGH 945
Query: 659 RPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
R +P +E++++ LQCW+ +PD+RP F+ + +L
Sbjct: 946 RMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDL 982
>AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth
factor receptor protein.
Length = 1210
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 742 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 796
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 797 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 852
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 853 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 912
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 913 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 972
Query: 700 EAP 702
P
Sbjct: 973 RDP 975
>AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor
receptor isoform a variant protein.
Length = 1081
Score = 127 bits (307), Expect = 1e-28
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 19/243 (7%)
Query: 470 IADREL-EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEM 526
+A +EL E T K + LD ++ + ++ +V L+GIC T+T L+ + +
Sbjct: 613 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIT-----QLMPFG 667
Query: 527 LLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVK 586
LL R+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VK
Sbjct: 668 CLLDYVREHKDN----IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK 723
Query: 587 IAGFGLSHLRSLHETPDYT-------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGA 639
I FGL+ L E + +W + E + Y ++DVWS+GV +WE++T G+
Sbjct: 724 ITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 783
Query: 640 TPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
PY ++ S + +G R QP +++ + ++CW +D D RP F L+IE + +
Sbjct: 784 KPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMA 843
Query: 700 EAP 702
P
Sbjct: 844 RDP 846
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 127 bits (306), Expect = 2e-28
Identities = 81/230 (35%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 491 IKTSEHENVISLIGICETNTTL-----LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSIT 544
+K H NVI L+G+C ++ +V+L +K L LL SR + I
Sbjct: 465 MKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH----IP 520
Query: 545 ENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-------HLRS 597
+L+ V +A GMEYL R +H+ L RN ++ ++ TV +A FGLS + R
Sbjct: 521 LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQ 580
Query: 598 LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRG 657
+W + E L Y K+DVW+FGV MWE+ T G TPY N ++ +L G
Sbjct: 581 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 640
Query: 658 MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA-PGTRN 706
R QP DEL+++ CW+ DP +RPTFS L ++L E+ P RN
Sbjct: 641 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRN 690
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 127 bits (306), Expect = 2e-28
Identities = 81/230 (35%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 491 IKTSEHENVISLIGICETNTTL-----LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSIT 544
+K H NVI L+G+C ++ +V+L +K L LL SR + I
Sbjct: 465 MKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH----IP 520
Query: 545 ENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-------HLRS 597
+L+ V +A GMEYL R +H+ L RN ++ ++ TV +A FGLS + R
Sbjct: 521 LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQ 580
Query: 598 LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRG 657
+W + E L Y K+DVW+FGV MWE+ T G TPY N ++ +L G
Sbjct: 581 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 640
Query: 658 MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA-PGTRN 706
R QP DEL+++ CW+ DP +RPTFS L ++L E+ P RN
Sbjct: 641 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRN 690
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein
protein.
Length = 364
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 124 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 182
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 183 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 241
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 242 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 299
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 300 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 355
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 774 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 832
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 833 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 891
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 892 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 949
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 950 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1005
>AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor
precursor PTK7-3 protein.
Length = 940
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 700 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 758
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 759 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 817
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 818 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 875
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 876 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 931
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 790 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 848
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 849 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 907
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 908 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 965
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 966 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1021
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 127 bits (306), Expect = 2e-28
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+FGVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine
kinase protein.
Length = 978
Score = 127 bits (306), Expect = 2e-28
Identities = 81/230 (35%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 491 IKTSEHENVISLIGICETNTTL-----LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSIT 544
+K H NVI L+G+C ++ +V+L +K L LL SR + I
Sbjct: 620 MKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH----IP 675
Query: 545 ENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-------HLRS 597
+L+ V +A GMEYL R +H+ L RN ++ ++ TV +A FGLS + R
Sbjct: 676 LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQ 735
Query: 598 LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRG 657
+W + E L Y K+DVW+FGV MWE+ T G TPY N ++ +L G
Sbjct: 736 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 795
Query: 658 MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA-PGTRN 706
R QP DEL+++ CW+ DP +RPTFS L ++L E+ P RN
Sbjct: 796 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRN 845
>AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein.
Length = 567
Score = 127 bits (306), Expect = 2e-28
Identities = 81/230 (35%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 491 IKTSEHENVISLIGICETNTTL-----LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSIT 544
+K H NVI L+G+C ++ +V+L +K L LL SR + I
Sbjct: 209 MKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH----IP 264
Query: 545 ENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-------HLRS 597
+L+ V +A GMEYL R +H+ L RN ++ ++ TV +A FGLS + R
Sbjct: 265 LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQ 324
Query: 598 LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRG 657
+W + E L Y K+DVW+FGV MWE+ T G TPY N ++ +L G
Sbjct: 325 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 384
Query: 658 MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA-PGTRN 706
R QP DEL+++ CW+ DP +RPTFS L ++L E+ P RN
Sbjct: 385 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRN 434
>X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein.
Length = 1354
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1009 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1066
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1067 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1126
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1127 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1158
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 875 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 918
>U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein.
Length = 999
Score = 126 bits (305), Expect = 2e-28
Identities = 81/230 (35%), Positives = 117/230 (50%), Gaps = 18/230 (7%)
Query: 491 IKTSEHENVISLIGICETNTTL-----LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSIT 544
+K H NVI L+G+C ++ +V+L +K L LL SR + I
Sbjct: 641 MKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH----IP 696
Query: 545 ENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-------HLRS 597
+L+ V +A GMEYL R +H+ L RN ++ ++ TV +A FGLS + R
Sbjct: 697 LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQ 756
Query: 598 LHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRG 657
+W + E L Y K+DVW+FGV MWE+ T G TPY N ++ +L G
Sbjct: 757 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEMYDYLLHG 816
Query: 658 MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEA-PGTRN 706
R QP DEL+++ CW+ DP +RPTFS L ++L E+ P RN
Sbjct: 817 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRN 866
>L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase
protein.
Length = 1354
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1009 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1066
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1067 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1126
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1127 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1158
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 875 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 918
>BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) protein.
Length = 1356
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1011 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1068
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1069 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1128
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1129 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1160
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 877 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 920
>AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial growth
factor receptor 2 protein.
Length = 1356
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1011 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1068
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1069 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1128
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1129 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1160
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 877 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 920
>AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein.
Length = 1356
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1011 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1068
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1069 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1128
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1129 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1160
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 877 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 920
>AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) variant
protein.
Length = 1451
Score = 126 bits (305), Expect = 2e-28
Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 12/152 (7%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVA+GME+L +RK +H+ L RN+++SE VKI FGL+ R +++ PDY R
Sbjct: 1106 QVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA--RDIYKDPDYVRKGDARLP 1163
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY +++ R+ G R P
Sbjct: 1164 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1223
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
Y E++Q L CW +P +RPTFS LV L
Sbjct: 1224 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1255
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 972 SEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCK 1015
>BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine
kinase protein.
Length = 894
Score = 125 bits (302), Expect = 5e-28
Identities = 76/229 (33%), Positives = 121/229 (52%), Gaps = 19/229 (8%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGIC------ETNTTLLVVLEDIKK-TLKEMLLL 529
++E + L E + +K +H NV+ LIG+C E+ +V+L +K L LL
Sbjct: 576 RSELEDFLSEA-VCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 634
Query: 530 SRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
SR D + + +++ +A GMEYL T++ +H+ L RN +++EN +V +A
Sbjct: 635 SRLGD----QPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVAD 690
Query: 590 FGLS-------HLRSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY 642
FGLS + R +W + E L Y K+DVWSFGV MWE+ T G TPY
Sbjct: 691 FGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPY 750
Query: 643 SHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
N ++ + RG R QP+ D L+ + +CW+++P +RP+F+ L
Sbjct: 751 PGVENSEIYDYLRRGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799
Score = 35.9 bits (79), Expect = 0.51
Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 19/174 (10%)
Query: 91 KNETQKCGGNNA----TSVYDTDVVAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYV 146
K + C +NA TS T V P QP NL L + T + + W+ + + ++
Sbjct: 199 KTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHC 258
Query: 147 IRAAVIET--------YSDYNLKPLEWRVSNETLNMELLNLHPGSKYNISVAALNYDEEG 198
AV+ D +PL + S + L +LHP + Y+I VA + +G
Sbjct: 259 TLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTS--SQG 316
Query: 199 PNI---TMVTETVIGTPDPSPPDVEIIQRRGDRMVVHIPKAK-NVNGPVSMYRI 248
P+ + ET G P PP+ R G + VH + + + G + YR+
Sbjct: 317 PSSWTHWLPVETPEGVP-LGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRL 369
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 125 bits (301), Expect = 6e-28
Identities = 76/236 (32%), Positives = 128/236 (54%), Gaps = 17/236 (7%)
Query: 473 RELEKTEKKQML---QELDLLIKTSEHENVISLIGICETNTTLLVVLEDIK-KTLKEMLL 528
+ L+ +++Q L +EL++ K + H NV+ L+G+C +VLE + + LK+ L
Sbjct: 830 KSLQSKDEQQQLDFRRELEMFGKLN-HANVVRLLGLCREAEPHYMVLEYVDLEDLKQFLR 888
Query: 529 LSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIA 588
+S+ +D + T+ KV +C QVA GME+L + VHK L RN ++S VK++
Sbjct: 889 ISKSKDEKLKSQPLSTKQKVA-LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVS 947
Query: 589 GFGLSHLRSLHETPDY--------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGAT 640
GLS + ++ + Y RW S E + + ++ K+DVW+ GVLMWEV T G
Sbjct: 948 ALGLS--KDVYNSEYYHFRQAWVALRWMSPEAILEGDFSTKSDVWASGVLMWEVFTHGEM 1005
Query: 641 PYSHSGNKDVGSRILRG-MRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P+ + +V + + G R QP +L+++ +CW + P +RP+FS + L
Sbjct: 1006 PHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein.
Length = 435
Score = 124 bits (298), Expect = 1e-27
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 27/242 (11%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ---- 532
+E + +L E ++L K H +VI L G C + LL+++E K +L+ L SR+
Sbjct: 130 SELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPG 188
Query: 533 ----------RDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISEN 582
+ + ++T ++ Q+++GM+YL K+VH+ L RN++++E
Sbjct: 189 YLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEG 248
Query: 583 GTVKIAGFGLSHLRSLHETPDYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWE 633
+KI+ FGLS R ++E Y + W + E L Y ++DVWSFGVL+WE
Sbjct: 249 RKMKISDFGLS--RDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE 306
Query: 634 VLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVI 693
++TLG PY + + + + G R +P +E++++ LQCW+ +PD+RP F+ +
Sbjct: 307 IVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISK 366
Query: 694 EL 695
+L
Sbjct: 367 DL 368
>X15786-1|CAA33787.1| 899|Homo sapiens retII protein.
Length = 899
Score = 124 bits (298), Expect = 1e-27
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 27/242 (11%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ---- 532
+E + +L E ++L K H +VI L G C + LL+++E K +L+ L SR+
Sbjct: 552 SELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPG 610
Query: 533 ----------RDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISEN 582
+ + ++T ++ Q+++GM+YL K+VH+ L RN++++E
Sbjct: 611 YLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEG 670
Query: 583 GTVKIAGFGLSHLRSLHETPDYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWE 633
+KI+ FGLS R ++E Y + W + E L Y ++DVWSFGVL+WE
Sbjct: 671 RKMKISDFGLS--RDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE 728
Query: 634 VLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVI 693
++TLG PY + + + + G R +P +E++++ LQCW+ +PD+RP F+ +
Sbjct: 729 IVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISK 788
Query: 694 EL 695
+L
Sbjct: 789 DL 790
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 124 bits (298), Expect = 1e-27
Identities = 68/214 (31%), Positives = 112/214 (52%), Gaps = 11/214 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 232 LDETAVMTKM-QHENLVRLLGVI-LDQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 285
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + V GMEYL ++K+VH+ L RN+++SE K++ FGL+ + L +
Sbjct: 286 ---QLLQFSLHVREGMEYLESKKLVHRDLAARNILVSEELVAKVSDFGLAKAERKGLDSS 342
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ ++ K+DVWSFGVL+WEV + G PY K+V + + R
Sbjct: 343 RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKRYRME 402
Query: 662 QPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P + + CW+ +P RP F L +L
Sbjct: 403 PPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 436
>M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor
protein.
Length = 885
Score = 124 bits (298), Expect = 1e-27
Identities = 75/229 (32%), Positives = 121/229 (52%), Gaps = 19/229 (8%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGIC------ETNTTLLVVLEDIKK-TLKEMLLL 529
++E + L E + +K +H NV+ LIG+C E+ +V+L +K L LL
Sbjct: 567 RSELEDFLSEA-VCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 625
Query: 530 SRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
SR D + + +++ +A GMEYL T++ +H+ L RN +++EN +V +A
Sbjct: 626 SRLGD----QPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVAD 681
Query: 590 FGLS-------HLRSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY 642
FGLS + R +W + E L Y K+DVWSFGV MWE+ T G TPY
Sbjct: 682 FGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPY 741
Query: 643 SHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
N ++ + +G R QP+ D L+ + +CW+++P +RP+F+ L
Sbjct: 742 PGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 790
Score = 35.1 bits (77), Expect = 0.89
Identities = 44/174 (25%), Positives = 73/174 (41%), Gaps = 19/174 (10%)
Query: 91 KNETQKCGGNNA----TSVYDTDVVAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYV 146
K + C +NA TS T V P QP NL L + T + + W+ + + ++
Sbjct: 199 KTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHC 258
Query: 147 IRAAVIET--------YSDYNLKPLEWRVSNETLNMELLNLHPGSKYNISVAALNYDEEG 198
AV+ D +PL + S + L +LHP + Y+I VA + +G
Sbjct: 259 TLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTS--SQG 316
Query: 199 PNI---TMVTETVIGTPDPSPPDVEIIQRRGDRMVVHIPKAK-NVNGPVSMYRI 248
P+ + ET G P P ++ R G + VH + + + G + YR+
Sbjct: 317 PSSWTHWLPVETPEGVPLGPPKNIS-ATRNGSQAFVHWQEPRAPLQGTLLGYRL 369
>M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary
thyroid carcinoma-encoded protein mRNA, complete cds. ).
Length = 503
Score = 124 bits (298), Expect = 1e-27
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 27/242 (11%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ---- 532
+E + +L E ++L K H +VI L G C + LL+++E K +L+ L SR+
Sbjct: 156 SELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPG 214
Query: 533 ----------RDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISEN 582
+ + ++T ++ Q+++GM+YL K+VH+ L RN++++E
Sbjct: 215 YLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEG 274
Query: 583 GTVKIAGFGLSHLRSLHETPDYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWE 633
+KI+ FGLS R ++E Y + W + E L Y ++DVWSFGVL+WE
Sbjct: 275 RKMKISDFGLS--RDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE 332
Query: 634 VLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVI 693
++TLG PY + + + + G R +P +E++++ LQCW+ +PD+RP F+ +
Sbjct: 333 IVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISK 392
Query: 694 EL 695
+L
Sbjct: 393 DL 394
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 124 bits (298), Expect = 1e-27
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 27/242 (11%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ---- 532
+E + +L E ++L K H +VI L G C + LL+++E K +L+ L SR+
Sbjct: 429 SELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPG 487
Query: 533 ----------RDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISEN 582
+ + ++T ++ Q+++GM+YL K+VH+ L RN++++E
Sbjct: 488 YLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEG 547
Query: 583 GTVKIAGFGLSHLRSLHETPDYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWE 633
+KI+ FGLS R ++E Y + W + E L Y ++DVWSFGVL+WE
Sbjct: 548 RKMKISDFGLS--RDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE 605
Query: 634 VLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVI 693
++TLG PY + + + + G R +P +E++++ LQCW+ +PD+RP F+ +
Sbjct: 606 IVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISK 665
Query: 694 EL 695
+L
Sbjct: 666 DL 667
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 123 bits (297), Expect = 2e-27
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 27/242 (11%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKK-TLKEMLLLSRQ---- 532
+E + +L E ++L K H +VI L G C + LL+++E K +L+ L SR+
Sbjct: 291 SELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPG 349
Query: 533 ----------RDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISEN 582
+ + ++T ++ Q+++GM+YL K+VH+ L RN++++E
Sbjct: 350 YLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEG 409
Query: 583 GTVKIAGFGLSHLRSLHETPDYTR---------WTSHEMLRQTRYNPKADVWSFGVLMWE 633
+KI+ FGLS R ++E Y + W + E L Y ++DVWSFGVL+WE
Sbjct: 410 RKMKISDFGLS--RDVYEEDPYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE 467
Query: 634 VLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVI 693
++TLG PY + + + + G R +P +E++++ LQCW+ +PD+RP F+ +
Sbjct: 468 IVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISK 527
Query: 694 EL 695
+L
Sbjct: 528 DL 529
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 123 bits (296), Expect = 3e-27
Identities = 69/237 (29%), Positives = 122/237 (51%), Gaps = 20/237 (8%)
Query: 476 EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQR 533
E T K ++ +D L++ + +H +++ L+G+C + T LV + + LL
Sbjct: 755 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVT-----QLMPHGCLLEYVH 809
Query: 534 DIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS 593
+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VKI FGL+
Sbjct: 810 EHKDN----IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLA 865
Query: 594 HLRSLHETPDYT--------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
L E +Y +W + E + ++ ++DVWS+GV +WE++T G PY
Sbjct: 866 RLLEGDEK-EYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGI 924
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+++ + +G R QP +++ V ++CW +D D RP F L E + + P
Sbjct: 925 PTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDP 981
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 123 bits (296), Expect = 3e-27
Identities = 69/237 (29%), Positives = 122/237 (51%), Gaps = 20/237 (8%)
Query: 476 EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQR 533
E T K ++ +D L++ + +H +++ L+G+C + T LV + + LL
Sbjct: 755 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVT-----QLMPHGCLLEYVH 809
Query: 534 DIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS 593
+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VKI FGL+
Sbjct: 810 EHKDN----IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLA 865
Query: 594 HLRSLHETPDYT--------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
L E +Y +W + E + ++ ++DVWS+GV +WE++T G PY
Sbjct: 866 RLLEGDEK-EYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGI 924
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+++ + +G R QP +++ V ++CW +D D RP F L E + + P
Sbjct: 925 PTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDP 981
>AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 variant protein.
Length = 892
Score = 123 bits (296), Expect = 3e-27
Identities = 69/237 (29%), Positives = 122/237 (51%), Gaps = 20/237 (8%)
Query: 476 EKTEKKQMLQELD--LLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQR 533
E T K ++ +D L++ + +H +++ L+G+C + T LV + + LL
Sbjct: 355 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVT-----QLMPHGCLLEYVH 409
Query: 534 DIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS 593
+ ++N I +L CVQ+A+GM YL R++VH+ L RN+++ VKI FGL+
Sbjct: 410 EHKDN----IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLA 465
Query: 594 HLRSLHETPDYT--------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHS 645
L E +Y +W + E + ++ ++DVWS+GV +WE++T G PY
Sbjct: 466 RLLEGDEK-EYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGI 524
Query: 646 GNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+++ + +G R QP +++ V ++CW +D D RP F L E + + P
Sbjct: 525 PTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDP 581
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 122 bits (295), Expect = 3e-27
Identities = 63/225 (28%), Positives = 112/225 (49%), Gaps = 15/225 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ QE ++K S H ++ G+C + +V E I L S + ++
Sbjct: 456 EFFQEAQTMMKLS-HPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLE----- 509
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLR----- 596
+++L++C V GM +L + + +H+ L RN ++ + VK++ FG++
Sbjct: 510 ---PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQY 566
Query: 597 -SLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
S T +W++ E+ +Y+ K+DVW+FG+LMWEV +LG PY N V ++
Sbjct: 567 VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS 626
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
+G R +P D ++Q+ CW P++RPTF L+ + P E
Sbjct: 627 QGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLRE 671
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 122 bits (295), Expect = 3e-27
Identities = 63/225 (28%), Positives = 112/225 (49%), Gaps = 15/225 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ QE ++K S H ++ G+C + +V E I L S + ++
Sbjct: 456 EFFQEAQTMMKLS-HPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLE----- 509
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLR----- 596
+++L++C V GM +L + + +H+ L RN ++ + VK++ FG++
Sbjct: 510 ---PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQY 566
Query: 597 -SLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
S T +W++ E+ +Y+ K+DVW+FG+LMWEV +LG PY N V ++
Sbjct: 567 VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS 626
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
+G R +P D ++Q+ CW P++RPTF L+ + P E
Sbjct: 627 QGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLRE 671
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 122 bits (295), Expect = 3e-27
Identities = 63/225 (28%), Positives = 112/225 (49%), Gaps = 15/225 (6%)
Query: 482 QMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFC 541
+ QE ++K S H ++ G+C + +V E I L S + ++
Sbjct: 478 EFFQEAQTMMKLS-HPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLE----- 531
Query: 542 SITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLR----- 596
+++L++C V GM +L + + +H+ L RN ++ + VK++ FG++
Sbjct: 532 ---PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQY 588
Query: 597 -SLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
S T +W++ E+ +Y+ K+DVW+FG+LMWEV +LG PY N V ++
Sbjct: 589 VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS 648
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
+G R +P D ++Q+ CW P++RPTF L+ + P E
Sbjct: 649 QGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLRE 693
>X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA for
tyrosine kinase receptor. ).
Length = 894
Score = 122 bits (294), Expect = 5e-27
Identities = 74/229 (32%), Positives = 120/229 (52%), Gaps = 19/229 (8%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGIC------ETNTTLLVVLEDIKK-TLKEMLLL 529
++E + L E + +K +H NV+ LIG+C E+ +V+L +K L LL
Sbjct: 576 RSELEDFLSEA-VCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 634
Query: 530 SRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
SR + + +++ +A GMEYL T++ +H+ L RN +++EN +V +A
Sbjct: 635 SRL----GGQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVAD 690
Query: 590 FGLS-------HLRSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY 642
FGLS + R +W + E L Y K+DVWSFGV MWE+ T G TPY
Sbjct: 691 FGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPY 750
Query: 643 SHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
N ++ + +G R QP+ D L+ + +CW+++P +RP+F+ L
Sbjct: 751 PGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799
Score = 35.1 bits (77), Expect = 0.89
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 19/174 (10%)
Query: 91 KNETQKCGGNNA----TSVYDTDVVAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYV 146
K + C +NA TS T V P QP NL L + T + + W+ + + ++
Sbjct: 199 KTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHC 258
Query: 147 IRAAVIET--------YSDYNLKPLEWRVSNETLNMELLNLHPGSKYNISVAALNYDEEG 198
AV+ D +PL + S + L +LHP Y+I VA + +G
Sbjct: 259 TLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHPPYHIRVACTS--SQG 316
Query: 199 PNI---TMVTETVIGTPDPSPPDVEIIQRRGDRMVVHIPKAK-NVNGPVSMYRI 248
P+ + ET G P PP+ R G + VH + + + G + YR+
Sbjct: 317 PSSWTHWLPVETPEGVP-LGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRL 369
>S65125-1|AAB20305.1| 894|Homo sapiens UFO protein.
Length = 894
Score = 122 bits (294), Expect = 5e-27
Identities = 74/229 (32%), Positives = 120/229 (52%), Gaps = 19/229 (8%)
Query: 477 KTEKKQMLQELDLLIKTSEHENVISLIGIC------ETNTTLLVVLEDIKK-TLKEMLLL 529
++E + L E + +K +H NV+ LIG+C E+ +V+L +K L LL
Sbjct: 576 RSELEDFLSEA-VCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 634
Query: 530 SRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAG 589
SR + + +++ +A GMEYL T++ +H+ L RN +++EN +V +A
Sbjct: 635 SRL----GGQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVAD 690
Query: 590 FGLS-------HLRSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY 642
FGLS + R +W + E L Y K+DVWSFGV MWE+ T G TPY
Sbjct: 691 FGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPY 750
Query: 643 SHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
N ++ + +G R QP+ D L+ + +CW+++P +RP+F+ L
Sbjct: 751 PGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799
Score = 35.1 bits (77), Expect = 0.89
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 19/174 (10%)
Query: 91 KNETQKCGGNNA----TSVYDTDVVAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYV 146
K + C +NA TS T V P QP NL L + T + + W+ + + ++
Sbjct: 199 KTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHC 258
Query: 147 IRAAVIET--------YSDYNLKPLEWRVSNETLNMELLNLHPGSKYNISVAALNYDEEG 198
AV+ D +PL + S + L +LHP Y+I VA + +G
Sbjct: 259 TLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHPPYHIRVACTS--SQG 316
Query: 199 PNI---TMVTETVIGTPDPSPPDVEIIQRRGDRMVVHIPKAK-NVNGPVSMYRI 248
P+ + ET G P PP+ R G + VH + + + G + YR+
Sbjct: 317 PSSWTHWLPVETPEGVP-LGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRL 369
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 122 bits (294), Expect = 5e-27
Identities = 66/198 (33%), Positives = 103/198 (52%), Gaps = 9/198 (4%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDY-TRWTSHEML 613
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E L
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASTQDTGKLPVKWTAPEAL 357
Query: 614 RQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQV 673
R+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++V
Sbjct: 358 REKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEV 417
Query: 674 CLQCWQVDPDERPTFSSL 691
CW +D RP+F L
Sbjct: 418 MKNCWHLDAAMRPSFLQL 435
>X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase
protein.
Length = 577
Score = 121 bits (291), Expect = 1e-26
Identities = 73/217 (33%), Positives = 114/217 (52%), Gaps = 11/217 (5%)
Query: 496 HENVISLIGIC-ETNTTLLVVLEDIK-KTLKEMLLLSRQRDIQNNKFCSITENKVLQICV 553
H N++ + +C E +V+L + LK L L + + ++ N +I++ ++ + +
Sbjct: 360 HRNLLPITHVCIEEGEKPMVILPYMNWGNLK--LFLRQCKLVEANNPQAISQQDLVHMAI 417
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSH------LRSLHETPDY-TR 606
Q+A GM YL R+++HK L RN +I + VKI LS L + + R
Sbjct: 418 QIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVR 477
Query: 607 WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYV 666
W + E L ++ +DVW+FGV +WE++TLG TPY ++ + + G R +QP
Sbjct: 478 WMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINC 537
Query: 667 GDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPG 703
DELF V CW +DP+ERP F LV LT F A G
Sbjct: 538 PDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 574
>BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein.
Length = 395
Score = 121 bits (291), Expect = 1e-26
Identities = 73/217 (33%), Positives = 114/217 (52%), Gaps = 11/217 (5%)
Query: 496 HENVISLIGIC-ETNTTLLVVLEDIK-KTLKEMLLLSRQRDIQNNKFCSITENKVLQICV 553
H N++ + +C E +V+L + LK L L + + ++ N +I++ ++ + +
Sbjct: 178 HRNLLPITHVCIEEGEKPMVILPYMNWGNLK--LFLRQCKLVEANNPQAISQQDLVHMAI 235
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSH------LRSLHETPDY-TR 606
Q+A GM YL R+++HK L RN +I + VKI LS L + + R
Sbjct: 236 QIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVR 295
Query: 607 WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYV 666
W + E L ++ +DVW+FGV +WE++TLG TPY ++ + + G R +QP
Sbjct: 296 WMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINC 355
Query: 667 GDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPG 703
DELF V CW +DP+ERP F LV LT F A G
Sbjct: 356 PDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 392
>AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 6
protein.
Length = 208
Score = 121 bits (291), Expect = 1e-26
Identities = 52/153 (33%), Positives = 88/153 (57%), Gaps = 6/153 (3%)
Query: 546 NKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT 605
+K+L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 45 SKLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSV 104
Query: 606 ------RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMR 659
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 105 GSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLR 164
Query: 660 PSQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 165 LYRPHLASEKVYTIMYSCWHEKADERPTFKILL 197
>X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein.
Length = 272
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 54 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 109
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 110 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 167
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 168 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 227
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 228 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 268
>X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein.
Length = 607
Score = 120 bits (289), Expect = 2e-26
Identities = 73/217 (33%), Positives = 115/217 (52%), Gaps = 11/217 (5%)
Query: 496 HENVISLIGIC-ETNTTLLVVLEDIK-KTLKEMLLLSRQRDIQNNKFCSITENKVLQICV 553
H N++ + +C E +V+L + LK L L + + ++ N +I+++ ++ + +
Sbjct: 390 HRNLLPITHVCIEEGEKPMVILPYMNWGNLK--LFLRQCKLVEANNPQAISQHDLVHMPI 447
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSH------LRSLHETPDY-TR 606
Q+A GM YL R+++HK L RN +I + VKI LS L + + R
Sbjct: 448 QIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVR 507
Query: 607 WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYV 666
W + E L ++ +DVW+FGV +WE++TLG TPY ++ + + G R +QP
Sbjct: 508 WMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINC 567
Query: 667 GDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPG 703
DELF V CW +DP+ERP F LV LT F A G
Sbjct: 568 PDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 604
>U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase
protein.
Length = 882
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 564 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 619
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 620 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 677
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 678 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 737
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 738 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 778
>U05682-1|AAA19236.1| 890|Homo sapiens Rse protein.
Length = 890
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 627
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 628 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 685
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 686 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 745
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 786
>D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase
protein.
Length = 884
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 566 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 621
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 622 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 679
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 680 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 739
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 740 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 780
>D17517-1|BAA04467.1| 890|Homo sapiens Sky protein.
Length = 890
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 627
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 628 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 685
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 686 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 745
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 786
>BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 627
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 628 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 685
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 686 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 745
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 786
>BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 627
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 628 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 685
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 686 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 745
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 786
>BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein.
Length = 518
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 200 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 255
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 256 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 313
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 314 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 373
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 374 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 414
>AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine
kinase variant protein.
Length = 951
Score = 120 bits (289), Expect = 2e-26
Identities = 72/221 (32%), Positives = 119/221 (53%), Gaps = 22/221 (9%)
Query: 491 IKTSEHENVISLIGICETNTTL------LVVLEDIKK-TLKEMLLLSRQRDIQNNKFCSI 543
+K +H +V L+G+ + +V+L +K L LL SR I N F ++
Sbjct: 633 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASR---IGENPF-NL 688
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPD 603
+++ V +A GMEYL +R +H+ L RN +++E+ TV +A FGLS R ++
Sbjct: 689 PLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLS--RKIYSGDY 746
Query: 604 Y---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRI 654
Y +W + E L Y ++DVW+FGV MWE++T G TPY+ N ++ + +
Sbjct: 747 YRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYL 806
Query: 655 LRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
+ G R QP ++++ + QCW DP +RP+F+ L +EL
Sbjct: 807 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMEL 847
>M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene
protein.
Length = 211
Score = 120 bits (288), Expect = 2e-26
Identities = 66/213 (30%), Positives = 112/213 (52%), Gaps = 19/213 (8%)
Query: 492 KTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQI 551
K H N++ LIG+C + +V+E ++ + L R + + +LQ+
Sbjct: 1 KQYSHPNIVRLIGVCTQKQPIYIVMELVQGG--DFLTFLRTEGAR------LRVKTLLQM 52
Query: 552 CVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS---------LHETP 602
A GMEYL ++ +H+ L RN +++E +KI+ FG+S + L + P
Sbjct: 53 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRDEADRVYAASGGLRQVP 112
Query: 603 DYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQ 662
+WT+ E L RY+ ++DV SFG+L+WE +LGA+PY + N+ + +G R
Sbjct: 113 --VKWTAPEALNYGRYSSESDVSSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 170
Query: 663 PSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
P D +F++ QCW +P +RP+FS++ EL
Sbjct: 171 PELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 203
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 120 bits (288), Expect = 2e-26
Identities = 69/227 (30%), Positives = 113/227 (49%), Gaps = 15/227 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E +++K S H ++ L G+C L +V E ++ LL+ R+ NK
Sbjct: 308 EEDFIEEAKVMMKLS-HSKLVQLYGVCIQRKPLYIVTE----FMENGCLLNYLRE---NK 359
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLH 599
+ + +L +C + GMEYL +H+ L RN ++S VKI+ FG++
Sbjct: 360 G-KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDD 418
Query: 600 ETPDY------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
E +W+ E+ +Y+ K+DVWSFGVLMWEV T G P+ + N V
Sbjct: 419 EYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEA 478
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
I G R +P +++V CW P+ RPTF+ L+ +T +E
Sbjct: 479 ISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAE 525
>AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes
variant 2 protein.
Length = 681
Score = 120 bits (288), Expect = 2e-26
Identities = 57/157 (36%), Positives = 91/157 (57%), Gaps = 11/157 (7%)
Query: 548 VLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS---------L 598
+LQ A GMEYL ++ +H+ L RN +++E +KI+ FG+S + L
Sbjct: 519 LLQTVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGL 578
Query: 599 HETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGM 658
+ P +WT+ E L RY+ ++DVWSFG+L+WE +LGA+PY + N+ + +G
Sbjct: 579 RQVP--VKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGG 636
Query: 659 RPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIEL 695
RP P D +F++ QCW +P +RP+FS++ EL
Sbjct: 637 RPPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQEL 673
>X69878-1|CAA49505.1| 1298|Homo sapiens protein ( H.sapiens Flt4 mRNA
for transmembrane tyrosine kinase. ).
Length = 1298
Score = 119 bits (287), Expect = 3e-26
Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 12/149 (8%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVARGME+L +RK +H+ L RN+++SE+ VKI FGL+ R +++ PDY R
Sbjct: 1020 QVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLA--RDIYKDPDYVRKGSARLP 1077
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY N++ R+ G R P
Sbjct: 1078 LKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRVRDGTRMRAP 1137
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+ + L CW DP RP FS LV
Sbjct: 1138 ELATPAIRHIMLNCWSGDPKARPAFSDLV 1166
Score = 33.5 bits (73), Expect = 2.7
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E++ ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 888 SEQRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCK 931
>X68203-1|CAA48290.1| 1304|Homo sapiens FTL4 protein.
Length = 1304
Score = 119 bits (287), Expect = 3e-26
Identities = 61/149 (40%), Positives = 87/149 (58%), Gaps = 12/149 (8%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVARGME+L +RK +H+ L RN+++SE+ VKI FGL+ R +++ PDY R
Sbjct: 1026 QVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLA--RDIYKDPDYVRKGSARLP 1083
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY N++ R+ G R P
Sbjct: 1084 LKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAP 1143
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+ ++ L CW DP RP FS LV
Sbjct: 1144 ELATPAIRRIMLNCWSGDPKARPAFSELV 1172
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 894 SEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCK 937
>U43143-1|AAA85215.1| 1298|Homo sapiens Flt4 protein.
Length = 1298
Score = 119 bits (287), Expect = 3e-26
Identities = 61/149 (40%), Positives = 87/149 (58%), Gaps = 12/149 (8%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVARGME+L +RK +H+ L RN+++SE+ VKI FGL+ R +++ PDY R
Sbjct: 1020 QVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLA--RDIYKDPDYVRKGSARLP 1077
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY N++ R+ G R P
Sbjct: 1078 LKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAP 1137
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+ ++ L CW DP RP FS LV
Sbjct: 1138 ELATPAIRRIMLNCWSGDPKARPAFSELV 1166
Score = 32.7 bits (71), Expect = 4.8
Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E + ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 888 SEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCK 931
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 119 bits (287), Expect = 3e-26
Identities = 69/227 (30%), Positives = 113/227 (49%), Gaps = 15/227 (6%)
Query: 480 KKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNK 539
++ ++E +++K S H ++ L G+C L +V E ++ LL+ R+ NK
Sbjct: 308 EEDFIEEAKVMMKLS-HSKLVQLYGVCIQRKPLYIVTE----FMENGCLLNYLRE---NK 359
Query: 540 FCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLH 599
+ + +L +C + GMEYL +H+ L RN ++S VKI+ FG++
Sbjct: 360 G-KLRKEMLLSVCQXICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDD 418
Query: 600 ETPDY------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSR 653
E +W+ E+ +Y+ K+DVWSFGVLMWEV T G P+ + N V
Sbjct: 419 EYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEA 478
Query: 654 ILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSE 700
I G R +P +++V CW P+ RPTF+ L+ +T +E
Sbjct: 479 ISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAE 525
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 119 bits (287), Expect = 3e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 279 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 334
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 335 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 390
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 391 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYE 450
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 451 LLEKDYRMKRPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein.
Length = 1363
Score = 119 bits (287), Expect = 3e-26
Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 12/149 (8%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVARGME+L +RK +H+ L RN+++SE+ VKI FGL+ R +++ PDY R
Sbjct: 1020 QVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLA--RDIYKDPDYVRKGSARLP 1077
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY N++ R+ G R P
Sbjct: 1078 LKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRVRDGTRMRAP 1137
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+ + L CW DP RP FS LV
Sbjct: 1138 ELATPAIRHIMLNCWSGDPKARPAFSELV 1166
Score = 33.5 bits (73), Expect = 2.7
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E++ ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 888 SEQRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCK 931
>AY233382-1|AAO89504.1| 1298|Homo sapiens VEGFR3 short form protein.
Length = 1298
Score = 119 bits (287), Expect = 3e-26
Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 12/149 (8%)
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTR------- 606
QVARGME+L +RK +H+ L RN+++SE+ VKI FGL+ R +++ PDY R
Sbjct: 1020 QVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLA--RDIYKDPDYVRKGSARLP 1077
Query: 607 --WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPY-SHSGNKDVGSRILRGMRPSQP 663
W + E + Y ++DVWSFGVL+WE+ +LGA+PY N++ R+ G R P
Sbjct: 1078 LKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRVRDGTRMRAP 1137
Query: 664 SYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+ + L CW DP RP FS LV
Sbjct: 1138 ELATPAIRHIMLNCWSGDPKARPAFSELV 1166
Score = 33.5 bits (73), Expect = 2.7
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 478 TEKKQMLQELDLLIKTSEHENVISLIGIC-ETNTTLLVVLEDIK 520
+E++ ++ EL +LI H NV++L+G C + L+V++E K
Sbjct: 888 SEQRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCK 931
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 1984 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 2040
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 2041 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 2100
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 2101 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 2158
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 2159 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2212
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 1990 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 2046
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 2047 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 2106
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 2107 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 2164
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 2165 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 1990 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 2046
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 2047 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 2106
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 2107 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 2164
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 2165 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQNQLQLF 2218
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 137 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 193
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 194 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 253
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 254 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 311
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 312 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 365
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 201 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 257
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 258 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 317
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 318 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 375
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 376 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 429
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 119 bits (286), Expect = 4e-26
Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 496 HENVISLIG-ICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQ 554
H N++ L+G I E L +V E + K L SR R + C +L+ +
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD-C------LLKFSLD 297
Query: 555 VARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS-HLRSLHETPDY-TRWTSHEM 612
V MEYL VH+ L RN+++SE+ K++ FGL+ S +T +WT+ E
Sbjct: 298 VCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEA 357
Query: 613 LRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQ 672
LR+ +++ K+DVWSFG+L+WE+ + G PY KDV R+ +G + P +++
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 673 VCLQCWQVDPDERPTFSSL 691
V CW +D RP+F L
Sbjct: 418 VMKNCWHLDAAMRPSFLQL 436
>AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 1990 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 2046
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 2047 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 2106
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 2107 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 2164
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 2165 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218
>AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 119 bits (286), Expect = 4e-26
Identities = 72/234 (30%), Positives = 119/234 (50%), Gaps = 19/234 (8%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
EK + L+E L+ K + H N++ +G+C N ++LE ++ ++L R+ +
Sbjct: 1984 EKIEFLKEAHLMSKFN-HPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATF 2040
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENG-----TVKIAGFGLS 593
+T ++ +CV +++G YL +H+ L RN ++S VKI FGL+
Sbjct: 2041 YGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLA 2100
Query: 594 HLRSLHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSH 644
R +++ Y RW + E L + ++DVWSFG+L+WE+LTLG PY
Sbjct: 2101 --RDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA 2158
Query: 645 SGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPF 698
N DV + + G R P D+L+ + QCW +PD+RPTF + +L F
Sbjct: 2159 HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2212
>AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 172
Score = 119 bits (286), Expect = 4e-26
Identities = 51/152 (33%), Positives = 87/152 (57%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 10 QLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 69
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 70 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 129
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 130 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 161
>AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 119 bits (286), Expect = 4e-26
Identities = 51/152 (33%), Positives = 88/152 (57%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS------HLRSLHE 600
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS S
Sbjct: 12 QLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSGYVLDDEYTSSVG 71
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+ RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 119 bits (286), Expect = 4e-26
Identities = 51/152 (33%), Positives = 88/152 (57%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLS------HLRSLHE 600
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS S
Sbjct: 12 QLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSGYVLDDEYTSSVG 71
Query: 601 TPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
+ RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>AB209405-1|BAD92642.1| 232|Homo sapiens RYK receptor-like tyrosine
kinase isoform 1 variant protein.
Length = 232
Score = 118 bits (285), Expect = 6e-26
Identities = 72/217 (33%), Positives = 114/217 (52%), Gaps = 11/217 (5%)
Query: 496 HENVISLIGIC-ETNTTLLVVLEDIK-KTLKEMLLLSRQRDIQNNKFCSITENKVLQICV 553
+ N++ + +C E +V+L + LK L L + + ++ N +I++ ++ + +
Sbjct: 15 YRNLLPITHVCIEEGEKPMVILPYMNWGNLK--LFLRQCKLVEANNPQAISQQDLVHMAI 72
Query: 554 QVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSH------LRSLHETPDY-TR 606
Q+A GM YL R+++HK L RN +I + VKI LS L + + R
Sbjct: 73 QIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVR 132
Query: 607 WTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYV 666
W + E L ++ +DVW+FGV +WE++TLG TPY ++ + + G R +QP
Sbjct: 133 WMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINC 192
Query: 667 GDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPG 703
DELF V CW +DP+ERP F LV LT F A G
Sbjct: 193 PDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 229
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 279 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 334
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 335 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 390
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 391 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 451 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 118 bits (284), Expect = 7e-26
Identities = 64/211 (30%), Positives = 110/211 (52%), Gaps = 16/211 (7%)
Query: 499 VISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQVARG 558
V L+GIC T+T LV + + LL R+ + + +L C+Q+A+G
Sbjct: 782 VSRLLGICLTSTVQLVT-----QLMPYGCLLDHVRENRGR----LGSQDLLNWCMQIAKG 832
Query: 559 MEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT-------RWTSHE 611
M YL ++VH+ L RN+++ VKI FGL+ L + ET + +W + E
Sbjct: 833 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 892
Query: 612 MLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELF 671
+ + R+ ++DVWS+GV +WE++T GA PY +++ + +G R QP +++
Sbjct: 893 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 952
Query: 672 QVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+ ++CW +D + RP F LV E + + P
Sbjct: 953 MIMVKCWMIDSECRPRFRELVSEFSRMARDP 983
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 279 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 334
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 335 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 390
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 391 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 451 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 298 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 353
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 354 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 409
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 410 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 470 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein
protein.
Length = 295
Score = 118 bits (284), Expect = 7e-26
Identities = 64/211 (30%), Positives = 110/211 (52%), Gaps = 16/211 (7%)
Query: 499 VISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQVARG 558
V L+GIC T+T LV + + LL R+ + + +L C+Q+A+G
Sbjct: 46 VSRLLGICLTSTVQLVT-----QLMPYGCLLDHVRENRGR----LGSQDLLNWCMQIAKG 96
Query: 559 MEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT-------RWTSHE 611
M YL ++VH+ L RN+++ VKI FGL+ L + ET + +W + E
Sbjct: 97 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 156
Query: 612 MLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELF 671
+ + R+ ++DVWS+GV +WE++T GA PY +++ + +G R QP +++
Sbjct: 157 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 216
Query: 672 QVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+ ++CW +D + RP F LV E + + P
Sbjct: 217 MIMVKCWMIDSECRPRFRELVSEFSRMARDP 247
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 118 bits (284), Expect = 7e-26
Identities = 64/211 (30%), Positives = 110/211 (52%), Gaps = 16/211 (7%)
Query: 499 VISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQVARG 558
V L+GIC T+T LV + + LL R+ + + +L C+Q+A+G
Sbjct: 782 VSRLLGICLTSTVQLVT-----QLMPYGCLLDHVRENRGR----LGSQDLLNWCMQIAKG 832
Query: 559 MEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT-------RWTSHE 611
M YL ++VH+ L RN+++ VKI FGL+ L + ET + +W + E
Sbjct: 833 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 892
Query: 612 MLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELF 671
+ + R+ ++DVWS+GV +WE++T GA PY +++ + +G R QP +++
Sbjct: 893 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 952
Query: 672 QVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+ ++CW +D + RP F LV E + + P
Sbjct: 953 MIMVKCWMIDSECRPRFRELVSEFSRMARDP 983
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 298 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 353
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 354 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 409
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 410 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 470 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 298 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 353
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 354 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 409
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 410 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 470 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 118 bits (284), Expect = 7e-26
Identities = 64/211 (30%), Positives = 110/211 (52%), Gaps = 16/211 (7%)
Query: 499 VISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQVARG 558
V L+GIC T+T LV + + LL R+ + + +L C+Q+A+G
Sbjct: 782 VSRLLGICLTSTVQLVT-----QLMPYGCLLDHVRENRGR----LGSQDLLNWCMQIAKG 832
Query: 559 MEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT-------RWTSHE 611
M YL ++VH+ L RN+++ VKI FGL+ L + ET + +W + E
Sbjct: 833 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 892
Query: 612 MLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELF 671
+ + R+ ++DVWS+GV +WE++T GA PY +++ + +G R QP +++
Sbjct: 893 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 952
Query: 672 QVCLQCWQVDPDERPTFSSLVIELTPFSEAP 702
+ ++CW +D + RP F LV E + + P
Sbjct: 953 MIMVKCWMIDSECRPRFRELVSEFSRMARDP 983
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 298 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 353
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 354 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 409
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 410 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 470 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 298 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 353
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 354 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 409
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 410 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 470 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 279 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 334
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 335 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 390
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 391 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 451 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 98 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 153
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 154 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 209
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 210 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 269
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 270 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 308
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 118 bits (284), Expect = 7e-26
Identities = 63/219 (28%), Positives = 116/219 (52%), Gaps = 14/219 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C ++ E + T +L R+ + Q
Sbjct: 316 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTREPPFYIITEFM--TYGNLLDYLRECNRQE- 371
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 372 ----VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 427
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L +++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 428 DTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 487
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSL 691
+ + R +P ++++++ CWQ +P +RP+F+ +
Sbjct: 488 LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 526
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 325 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 379
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 380 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 436
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 437 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 496
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 497 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 533
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 325 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 379
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 380 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 436
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 437 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 496
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 497 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 533
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 338 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 392
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 393 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 449
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 450 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 509
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 510 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 546
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 310 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 364
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 365 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 421
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 422 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 481
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 482 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 518
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 325 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 379
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 380 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 436
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 437 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 496
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 497 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 533
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 310 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 364
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 365 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 421
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 422 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 481
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 482 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 518
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 325 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 379
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 380 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 436
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 437 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 496
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 497 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 533
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 310 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 364
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 365 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 421
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 422 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 481
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 482 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 518
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 325 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 379
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 380 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 436
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 437 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 496
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 497 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 533
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 118 bits (283), Expect = 1e-25
Identities = 64/217 (29%), Positives = 112/217 (51%), Gaps = 14/217 (6%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E ++ L+E ++ K +H N++ L+G+C +V E + LL R+
Sbjct: 310 EVEEFLKEAAVM-KEIKHPNLVQLLGVCTLEPPFYIVTE----YMPYGNLLDYLRECNRE 364
Query: 539 KFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS- 597
+ ++ +L + Q++ MEYL + +H+ L RN ++ EN VK+A FGLS L +
Sbjct: 365 EVTAVV---LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTG 421
Query: 598 ----LHETPDYT-RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGS 652
H + +WT+ E L ++ K+DVW+FGVL+WE+ T G +PY V
Sbjct: 422 DTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD 481
Query: 653 RILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFS 689
+ +G R QP +++++ CW+ P +RP+F+
Sbjct: 482 LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFA 518
>AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 118 bits (283), Expect = 1e-25
Identities = 51/152 (33%), Positives = 86/152 (56%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 12 QLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 71
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKYDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 117 bits (282), Expect = 1e-25
Identities = 69/224 (30%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Query: 481 KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKF 540
+QMLQ +K H+++++L + + ++ E + K +L L R D K
Sbjct: 229 QQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKG--SLLELLRDSD---EKV 283
Query: 541 CSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSL 598
++E +L I QVA GM YL ++ +H+ L RN+++ EN K+ FGL+ L +
Sbjct: 284 LPVSE--LLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDV 341
Query: 599 HETPDYT---RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
+ + D+ +WT+ E L + Y+ K+DVWSFG+L+ E+ + G PY N + R+
Sbjct: 342 YLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVD 401
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
G R P + ++ L CW DP++RP F +L L+ F+
Sbjct: 402 AGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFT 445
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 117 bits (282), Expect = 1e-25
Identities = 69/224 (30%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Query: 481 KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKF 540
+QMLQ +K H+++++L + + ++ E + K +L L R D K
Sbjct: 229 QQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKG--SLLELLRDSD---EKV 283
Query: 541 CSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSL 598
++E +L I QVA GM YL ++ +H+ L RN+++ EN K+ FGL+ L +
Sbjct: 284 LPVSE--LLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDV 341
Query: 599 HETPDYT---RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
+ + D+ +WT+ E L + Y+ K+DVWSFG+L+ E+ + G PY N + R+
Sbjct: 342 YLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVD 401
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
G R P + ++ L CW DP++RP F +L L+ F+
Sbjct: 402 AGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFT 445
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 117 bits (282), Expect = 1e-25
Identities = 69/224 (30%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Query: 481 KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKF 540
+QMLQ +K H+++++L + + ++ E + K +L L R D K
Sbjct: 229 QQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKG--SLLELLRDSD---EKV 283
Query: 541 CSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSL 598
++E +L I QVA GM YL ++ +H+ L RN+++ EN K+ FGL+ L +
Sbjct: 284 LPVSE--LLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDV 341
Query: 599 HETPDYT---RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
+ + D+ +WT+ E L + Y+ K+DVWSFG+L+ E+ + G PY N + R+
Sbjct: 342 YLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVD 401
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
G R P + ++ L CW DP++RP F +L L+ F+
Sbjct: 402 AGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFT 445
>AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein.
Length = 451
Score = 117 bits (282), Expect = 1e-25
Identities = 69/224 (30%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Query: 481 KQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKF 540
+QMLQ +K H+++++L + + ++ E + K +L L R D K
Sbjct: 229 QQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKG--SLLELLRDSD---EKV 283
Query: 541 CSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSL 598
++E +L I QVA GM YL ++ +H+ L RN+++ EN K+ FGL+ L +
Sbjct: 284 LPVSE--LLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDV 341
Query: 599 HETPDYT---RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRIL 655
+ + D+ +WT+ E L + Y+ K+DVWSFG+L+ E+ + G PY N + R+
Sbjct: 342 YLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVD 401
Query: 656 RGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFS 699
G R P + ++ L CW DP++RP F +L L+ F+
Sbjct: 402 AGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFT 445
>AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 117 bits (282), Expect = 1e-25
Identities = 50/152 (32%), Positives = 87/152 (57%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEYL +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 12 QLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 71
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K+D+W+FGVLMW++ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWKIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 116 bits (280), Expect = 2e-25
Identities = 71/243 (29%), Positives = 123/243 (50%), Gaps = 14/243 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + H +V+ L+G+ LVV+E + + L S + + +NN
Sbjct: 1055 ERIEFLNEASVMKGFTCH-HVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENN 1113
Query: 539 KFCSI-TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
T +++Q+ ++A GM YL+ +K VH+ L RN +++ + TVKI FG++ R
Sbjct: 1114 PGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMT--RD 1171
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW + E L+ + +D+WSFGV++WE+ +L PY N+
Sbjct: 1172 IYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNE 1231
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G QP + + + CWQ +P+ RPTF ++ L P +S
Sbjct: 1232 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLE-IVNLLKDDLHPSFPEVS 1290
Query: 709 FTH 711
F H
Sbjct: 1291 FFH 1293
>AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 116 bits (280), Expect = 2e-25
Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEY +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 12 QLLEMCKDVCEAMEYQESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 71
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 116 bits (279), Expect = 3e-25
Identities = 65/201 (32%), Positives = 108/201 (53%), Gaps = 12/201 (5%)
Query: 484 LQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSI 543
L E ++ K +HEN++ L+G+ + L +V+E + K L +R R + N
Sbjct: 274 LDETAVMTKM-QHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTA---- 327
Query: 544 TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHL--RSLHET 601
++LQ + VA GMEYL ++K+VH+ L RN+++SE+ K++ FGL+ + L +
Sbjct: 328 ---QLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query: 602 PDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPS 661
+WT+ E L+ + K+DVWSFGVL+WEV + G PY K+V + +G R
Sbjct: 385 RLPVKWTAPEALKHG-FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRME 443
Query: 662 QPSYVGDELFQVCLQCWQVDP 682
P + + CW+ +P
Sbjct: 444 PPEGCPGPVHVLMSSCWEAEP 464
>AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 116 bits (279), Expect = 3e-25
Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEY +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 12 QLLEMCKDVCEAMEYPESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 71
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 116 bits (279), Expect = 3e-25
Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 6/152 (3%)
Query: 547 KVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYT- 605
++L++C V MEY +++ +H+ L RN ++++ G VK++ FGLS E
Sbjct: 12 QLLEMCKDVCEAMEYPESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVG 71
Query: 606 -----RWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRP 660
RW+ E+L ++++ K+D+W+FGVLMWE+ +LG PY N + I +G+R
Sbjct: 72 SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL 131
Query: 661 SQPSYVGDELFQVCLQCWQVDPDERPTFSSLV 692
+P ++++ + CW DERPTF L+
Sbjct: 132 YRPHLASEKVYTIMYSCWHEKADERPTFKILL 163
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 116 bits (278), Expect = 4e-25
Identities = 71/243 (29%), Positives = 122/243 (50%), Gaps = 14/243 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + H +V+ L+G+ LVV+E + + L S + + +NN
Sbjct: 1067 ERIEFLNEASVMKGFTCH-HVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENN 1125
Query: 539 KFCSI-TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
T +++Q+ ++A GM YL+ +K VH+ L RN +++ + TVKI FG++ R
Sbjct: 1126 PGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMT--RD 1183
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW + E L+ + +D+WSFGV++WE+ +L PY N+
Sbjct: 1184 IYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNE 1243
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G QP + + + CWQ +P RPTF ++ L P +S
Sbjct: 1244 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLE-IVNLLKDDLHPSFPEVS 1302
Query: 709 FTH 711
F H
Sbjct: 1303 FFH 1305
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 116 bits (278), Expect = 4e-25
Identities = 71/243 (29%), Positives = 122/243 (50%), Gaps = 14/243 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + H +V+ L+G+ LVV+E + + L S + + +NN
Sbjct: 1067 ERIEFLNEASVMKGFTCH-HVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENN 1125
Query: 539 KFCSI-TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
T +++Q+ ++A GM YL+ +K VH+ L RN +++ + TVKI FG++ R
Sbjct: 1126 PGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMT--RD 1183
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW + E L+ + +D+WSFGV++WE+ +L PY N+
Sbjct: 1184 IYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNE 1243
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G QP + + + CWQ +P RPTF ++ L P +S
Sbjct: 1244 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLE-IVNLLKDDLHPSFPEVS 1302
Query: 709 FTH 711
F H
Sbjct: 1303 FFH 1305
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 116 bits (278), Expect = 4e-25
Identities = 71/243 (29%), Positives = 122/243 (50%), Gaps = 14/243 (5%)
Query: 479 EKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNN 538
E+ + L E ++ + H +V+ L+G+ LVV+E + + L S + + +NN
Sbjct: 1055 ERIEFLNEASVMKGFTCH-HVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENN 1113
Query: 539 KFCSI-TENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRS 597
T +++Q+ ++A GM YL+ +K VH+ L RN +++ + TVKI FG++ R
Sbjct: 1114 PGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMT--RD 1171
Query: 598 LHETPDY---------TRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNK 648
++ET Y RW + E L+ + +D+WSFGV++WE+ +L PY N+
Sbjct: 1172 IYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNE 1231
Query: 649 DVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLS 708
V ++ G QP + + + CWQ +P RPTF ++ L P +S
Sbjct: 1232 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLE-IVNLLKDDLHPSFPEVS 1290
Query: 709 FTH 711
F H
Sbjct: 1291 FFH 1293
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,568,769
Number of Sequences: 224733
Number of extensions: 4671658
Number of successful extensions: 16099
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1852
Number of HSP's successfully gapped in prelim test: 955
Number of HSP's that attempted gapping in prelim test: 9712
Number of HSP's gapped (non-prelim): 4306
length of query: 728
length of database: 73,234,838
effective HSP length: 95
effective length of query: 633
effective length of database: 51,885,203
effective search space: 32843333499
effective search space used: 32843333499
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)
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