Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000769-TA|BGIBMGA000769-PA|IPR011701|Major facilitator
superfamily MFS_1, IPR007114|Major facilitator superfamily,
IPR005829|Sugar transporter superfamily
(479 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q5SR56 Cluster: Hippocampus abundant transcript-like pr... 578 e-163
UniRef50_UPI0000E4722E Cluster: PREDICTED: hypothetical protein;... 547 e-154
UniRef50_UPI00002053B2 Cluster: PREDICTED: hippocampus abundant ... 544 e-153
UniRef50_Q965I9 Cluster: Putative uncharacterized protein T25D3.... 486 e-136
UniRef50_Q9VPE0 Cluster: CG18281-PA; n=2; Drosophila melanogaste... 189 2e-46
UniRef50_Q5VZR4 Cluster: Hippocampus abundant transcript-like pr... 157 8e-37
UniRef50_Q0C4X1 Cluster: Tetracycline-efflux transporter; n=1; H... 150 9e-35
UniRef50_Q89MY8 Cluster: Tetracycline resistance protein; n=7; B... 146 1e-33
UniRef50_Q28RT4 Cluster: Major facilitator superfamily MFS_1; n=... 143 1e-32
UniRef50_Q4RG87 Cluster: Chromosome 12 SCAF15104, whole genome s... 142 2e-32
UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1; P... 133 8e-30
UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1; B... 131 5e-29
UniRef50_Q9A8S0 Cluster: Tetracycline resistance protein; n=3; A... 130 1e-28
UniRef50_A7NRD2 Cluster: Major facilitator superfamily MFS_1; n=... 128 3e-28
UniRef50_A6U8Y2 Cluster: Major facilitator superfamily MFS_1; n=... 128 4e-28
UniRef50_A3WCL4 Cluster: Permease; n=1; Erythrobacter sp. NAP1|R... 127 7e-28
UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=... 126 2e-27
UniRef50_A2SG94 Cluster: Tetracycline-efflux transporter; n=2; P... 125 3e-27
UniRef50_UPI000038DC0A Cluster: COG0477: Permeases of the major ... 124 4e-27
UniRef50_Q3BM88 Cluster: Drug:H+ antiporter-1 family protein; n=... 122 2e-26
UniRef50_A3UGP9 Cluster: Probable transporter; n=1; Oceanicaulis... 122 2e-26
UniRef50_Q9RX43 Cluster: Tetracycline-efflux transporter; n=2; D... 122 3e-26
UniRef50_A0GXY1 Cluster: Major facilitator superfamily MFS_1; n=... 121 4e-26
UniRef50_Q2G331 Cluster: Major facilitator superfamily MFS_1; n=... 120 6e-26
UniRef50_Q2MDB3 Cluster: Tetracycline efllux protein; n=6; Prote... 120 6e-26
UniRef50_Q8F6D6 Cluster: Tetracycline resistance protein, class ... 120 8e-26
UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3; Proteoba... 120 1e-25
UniRef50_A3VN57 Cluster: Permease; n=1; Parvularcula bermudensis... 118 4e-25
UniRef50_Q62C01 Cluster: Multidrug resistance protein; n=16; Pro... 117 8e-25
UniRef50_Q4ZVR8 Cluster: General substrate transporter:Major fac... 117 8e-25
UniRef50_A3U1K1 Cluster: Putative transport transmembrane protei... 114 4e-24
UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS) per... 113 7e-24
UniRef50_P02981 Cluster: Tetracycline resistance protein, class ... 112 2e-23
UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -... 112 2e-23
UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=... 111 5e-23
UniRef50_Q97L04 Cluster: Permease, probably tetracycline resista... 109 2e-22
UniRef50_Q5N0B7 Cluster: Multidrug-efflux transporter quinolene ... 109 2e-22
UniRef50_A0LD21 Cluster: Major facilitator superfamily MFS_1; n=... 109 2e-22
UniRef50_A3VAE1 Cluster: Tetracycline resistance protein; n=3; R... 107 5e-22
UniRef50_Q07282 Cluster: Tetracycline resistance protein, class ... 106 1e-21
UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=... 106 1e-21
UniRef50_Q65F99 Cluster: Blt; n=2; Bacillus|Rep: Blt - Bacillus ... 102 2e-20
UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA - Ac... 102 2e-20
UniRef50_Q8DMH7 Cluster: Multidrug-efflux transporter; n=2; Cyan... 101 3e-20
UniRef50_Q0LMR4 Cluster: Major facilitator superfamily MFS_1 pre... 101 4e-20
UniRef50_A5FYH1 Cluster: Major facilitator superfamily MFS_1 pre... 101 4e-20
UniRef50_Q6MQK5 Cluster: Multidrug resistance protein; n=1; Bdel... 100 7e-20
UniRef50_Q1IVW2 Cluster: Major facilitator superfamily MFS_1; n=... 100 7e-20
UniRef50_Q8VVJ1 Cluster: TetA protein; n=5; Actinomycetales|Rep:... 99 2e-19
UniRef50_Q75TC8 Cluster: Multidrug-efflux transporter; n=3; Geob... 99 3e-19
UniRef50_A7H6K9 Cluster: Major facilitator superfamily MFS_1; n=... 98 5e-19
UniRef50_Q9KDN7 Cluster: Multidrug-efflux transporter; n=1; Baci... 95 5e-18
UniRef50_Q5WGK5 Cluster: Major facilitator (MFS) superfamily mul... 95 5e-18
UniRef50_Q9A9E1 Cluster: Multidrug resistance protein, putative;... 93 1e-17
UniRef50_A7CRQ2 Cluster: Major facilitator superfamily MFS_1 pre... 93 1e-17
UniRef50_Q0W1K3 Cluster: Putative permease; n=1; uncultured meth... 93 1e-17
UniRef50_Q6V4U1 Cluster: Putative multidrug efflux protein; n=1;... 92 3e-17
UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS famil... 92 3e-17
UniRef50_Q0AX92 Cluster: Multidrug-efflux transporter; n=1; Synt... 91 8e-17
UniRef50_Q9KBZ9 Cluster: Multidrug-efflux transporter; n=2; Baci... 89 2e-16
UniRef50_A1B6I1 Cluster: Major facilitator superfamily MFS_1; n=... 89 3e-16
UniRef50_Q9I4K4 Cluster: Probable major facilitator superfamily ... 86 2e-15
UniRef50_Q2SGJ5 Cluster: Permease of the major facilitator super... 86 2e-15
UniRef50_Q88YJ0 Cluster: Multidrug transport protein; n=5; Lacto... 85 4e-15
UniRef50_A3IH26 Cluster: Multidrug resistance protein, putative;... 85 4e-15
UniRef50_A7NVP3 Cluster: Chromosome chr18 scaffold_1, whole geno... 85 5e-15
UniRef50_A4ING5 Cluster: Multidrug-efflux transporter; n=1; Geob... 83 1e-14
UniRef50_Q0W0M4 Cluster: Putative permease; n=1; uncultured meth... 83 1e-14
UniRef50_A6G4P6 Cluster: Multidrug resistance protein, putative;... 82 3e-14
UniRef50_P39843 Cluster: Multidrug resistance protein 2; n=18; F... 82 3e-14
UniRef50_Q192M5 Cluster: Major facilitator superfamily MFS_1; n=... 81 5e-14
UniRef50_Q0W242 Cluster: Putative permease; n=1; uncultured meth... 79 3e-13
UniRef50_Q1D6T2 Cluster: Putative multidrug resistance protein; ... 79 3e-13
UniRef50_Q21E97 Cluster: Major facilitator superfamily MFS_1; n=... 77 8e-13
UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera arane... 77 8e-13
UniRef50_A5GP24 Cluster: Permease of the major facilitator super... 77 1e-12
UniRef50_Q8GR72 Cluster: Multidrug efflux pump; n=7; Lactobacill... 77 1e-12
UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA... 75 4e-12
UniRef50_UPI00005842F8 Cluster: PREDICTED: hypothetical protein ... 74 7e-12
UniRef50_Q8F4V6 Cluster: Tetracycline resistance protein; n=4; L... 74 1e-11
UniRef50_A6BZ30 Cluster: Major facilitator superfamily MFS_1 tra... 73 1e-11
UniRef50_A4AC28 Cluster: Tetracycline-efflux transporter; n=1; C... 73 1e-11
UniRef50_A3I4T4 Cluster: Blt; n=1; Bacillus sp. B14905|Rep: Blt ... 73 1e-11
UniRef50_Q8KDQ3 Cluster: Drug resistance protein, putative; n=10... 73 2e-11
UniRef50_Q846S5 Cluster: Adventurous gliding motility protein P;... 71 9e-11
UniRef50_P39637 Cluster: Uncharacterized protein ywfA; n=2; Baci... 70 1e-10
UniRef50_A5B1K4 Cluster: Putative uncharacterized protein; n=1; ... 70 2e-10
UniRef50_Q550B7 Cluster: Putative uncharacterized protein; n=2; ... 70 2e-10
UniRef50_Q67MU6 Cluster: Putative multidrug efflux protein; n=1;... 69 2e-10
UniRef50_UPI00015B5592 Cluster: PREDICTED: similar to GA19110-PA... 69 3e-10
UniRef50_A7HKI1 Cluster: Major facilitator superfamily MFS_1; n=... 69 3e-10
UniRef50_A3I0S1 Cluster: Multidrug transporter, putative; n=1; A... 69 3e-10
UniRef50_Q89NI8 Cluster: Bll3850 protein; n=1; Bradyrhizobium ja... 69 4e-10
UniRef50_Q54N46 Cluster: Putative uncharacterized protein; n=1; ... 69 4e-10
UniRef50_Q63BE3 Cluster: Multidrug resistance protein; n=3; Baci... 68 6e-10
UniRef50_Q9K9Q3 Cluster: BH2592 protein; n=2; Bacillus|Rep: BH25... 67 8e-10
UniRef50_A7HUQ1 Cluster: Major facilitator superfamily MFS_1; n=... 67 1e-09
UniRef50_A7RGX9 Cluster: Predicted protein; n=1; Nematostella ve... 67 1e-09
UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1; P... 67 1e-09
UniRef50_A3CSK5 Cluster: Major facilitator superfamily MFS_1 pre... 67 1e-09
UniRef50_A0B6G9 Cluster: Major facilitator superfamily MFS_1; n=... 66 1e-09
UniRef50_UPI0000E4A5F1 Cluster: PREDICTED: similar to MGC84630 p... 66 3e-09
UniRef50_A4SRL1 Cluster: Major facilitator superfamily permease;... 66 3e-09
UniRef50_Q398I1 Cluster: Major facilitator superfamily (MFS_1) t... 65 3e-09
UniRef50_Q4WJ43 Cluster: Tetracycline transporter, putative; n=1... 65 4e-09
UniRef50_A1I922 Cluster: Major facilitator superfamily MFS_1 pre... 64 6e-09
UniRef50_Q0W0C7 Cluster: Putative permease; n=1; uncultured meth... 64 6e-09
UniRef50_A1ZHT1 Cluster: Major facilitator family transporter, p... 64 1e-08
UniRef50_Q83X84 Cluster: Putative efflux transporter protein; n=... 63 1e-08
UniRef50_A4BEE3 Cluster: Major facilitator superfamily MFS_1; n=... 63 1e-08
UniRef50_Q54IT2 Cluster: Putative uncharacterized protein; n=1; ... 63 1e-08
UniRef50_Q8TUA4 Cluster: Class H tetracycline resistance efflux ... 63 1e-08
UniRef50_A6Q5H8 Cluster: Multidrug-efflux transporter, MFS famil... 63 2e-08
UniRef50_Q54JQ8 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08
UniRef50_Q8TZJ0 Cluster: Sucrose transport protein; n=3; Thermoc... 62 2e-08
UniRef50_Q9RN46 Cluster: 12-TMS multidrug efflux protein homolog... 62 3e-08
UniRef50_Q6ET95 Cluster: Tetracycline transporter protein-like; ... 62 3e-08
UniRef50_Q3DYD2 Cluster: Tetracycline resistance protein; n=1; C... 62 4e-08
UniRef50_Q14J11 Cluster: Multidrug transporter; n=11; Francisell... 62 4e-08
UniRef50_A3I8X0 Cluster: Putative uncharacterized protein; n=2; ... 62 4e-08
UniRef50_A0Z2L4 Cluster: Multidrug-efflux transporter; n=1; mari... 62 4e-08
UniRef50_Q64DZ9 Cluster: Permeases of the major facilitator supe... 61 5e-08
UniRef50_Q7NNZ0 Cluster: Glr0268 protein; n=1; Gloeobacter viola... 60 1e-07
UniRef50_A3ZND9 Cluster: Multidrug resistance protein; n=1; Blas... 60 1e-07
UniRef50_Q14728 Cluster: Tetracycline transporter-like protein; ... 60 1e-07
UniRef50_Q58955 Cluster: Uncharacterized MFS-type transporter MJ... 60 1e-07
UniRef50_Q86B08 Cluster: Similar to Leptospira interrogans serov... 60 1e-07
UniRef50_A1S0L4 Cluster: Major facilitator superfamily MFS_1; n=... 60 1e-07
UniRef50_Q649G3 Cluster: Multidrug efflux transporter; n=1; uncu... 60 2e-07
UniRef50_A3XY06 Cluster: Putative mfs transporter; n=1; Vibrio s... 59 2e-07
UniRef50_A7RPG8 Cluster: Predicted protein; n=1; Nematostella ve... 59 2e-07
UniRef50_A7D0E0 Cluster: Major facilitator superfamily MFS_1; n=... 59 2e-07
UniRef50_Q2YHS5 Cluster: Putative uncharacterized protein; n=1; ... 59 3e-07
UniRef50_A0NRK3 Cluster: Multidrug transporter, putative; n=1; S... 58 5e-07
UniRef50_A7STS4 Cluster: Predicted protein; n=1; Nematostella ve... 58 5e-07
UniRef50_Q12ZN0 Cluster: Major facilitator superfamily (MFS) tra... 58 5e-07
UniRef50_Q67KL5 Cluster: Putative sugar transport protein; n=1; ... 58 7e-07
UniRef50_P0A0J7 Cluster: Quinolone resistance protein norA; n=23... 58 7e-07
UniRef50_Q8NBP5 Cluster: Major facilitator superfamily domain-co... 58 7e-07
UniRef50_Q9RSF5 Cluster: Drug transport protein; n=4; Deinococci... 57 9e-07
UniRef50_Q8D344 Cluster: YajR protein; n=1; Wigglesworthia gloss... 57 9e-07
UniRef50_Q890A4 Cluster: Transport protein; n=6; Lactobacillacea... 57 9e-07
UniRef50_Q2ARG1 Cluster: General substrate transporter:Major fac... 57 9e-07
UniRef50_A5EUI4 Cluster: Putative Permease of the major facilita... 57 9e-07
UniRef50_Q2RM84 Cluster: Major facilitator superfamily MFS_1 pre... 57 1e-06
UniRef50_Q1AYP7 Cluster: Major facilitator superfamily MFS_1; n=... 56 2e-06
UniRef50_A5ALX6 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_Q0VSH1 Cluster: Major facilitator family transporter; n... 56 2e-06
UniRef50_A7S0P7 Cluster: Predicted protein; n=3; Nematostella ve... 56 3e-06
UniRef50_A7EBM9 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-06
UniRef50_Q8CX74 Cluster: Multidrug resistance protein; n=1; Ocea... 55 4e-06
UniRef50_Q9V395 Cluster: CG5760-PA; n=5; Endopterygota|Rep: CG57... 55 4e-06
UniRef50_Q7UXH6 Cluster: Probable MFS transporter; n=1; Pirellul... 55 5e-06
UniRef50_Q21M22 Cluster: Major facilitator superfamily MFS_1; n=... 55 5e-06
UniRef50_Q15ZK9 Cluster: Major facilitator superfamily MFS_1 pre... 55 5e-06
UniRef50_Q0FEF9 Cluster: Drug resistance transporter, Bcr/CflA s... 55 5e-06
UniRef50_A4WGP8 Cluster: Major facilitator superfamily MFS_1 pre... 55 5e-06
UniRef50_Q31IV1 Cluster: Major facilitator superfamily (MFS) tra... 54 6e-06
UniRef50_Q122U2 Cluster: Major facilitator superfamily MFS_1 pre... 54 6e-06
UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE466... 54 6e-06
UniRef50_Q0W1D9 Cluster: Permease; n=1; uncultured methanogenic ... 54 6e-06
UniRef50_Q5L371 Cluster: Drug-efflux transporter; n=2; Geobacill... 54 8e-06
UniRef50_Q1V9Z1 Cluster: Putative sugar transport protein; n=1; ... 54 8e-06
UniRef50_Q869U5 Cluster: Similar to Xanthomonas campestris (Pv. ... 54 8e-06
UniRef50_A7SUG3 Cluster: Predicted protein; n=1; Nematostella ve... 54 8e-06
UniRef50_A7I7E2 Cluster: Major facilitator superfamily MFS_1; n=... 54 8e-06
UniRef50_A3H8V2 Cluster: Major facilitator superfamily MFS_1; n=... 54 8e-06
UniRef50_Q8ZQ25 Cluster: Multidrug resistance protein mdtG; n=36... 54 8e-06
UniRef50_UPI0000499030 Cluster: major facilitator superfamily pr... 54 1e-05
UniRef50_Q30UI0 Cluster: Major facilitator superfamily MFS_1; n=... 54 1e-05
UniRef50_Q0S8F1 Cluster: Multidrug transporter, MFS superfamily ... 54 1e-05
UniRef50_Q17KH4 Cluster: Adenylate cyclase, putative; n=1; Aedes... 54 1e-05
UniRef50_Q2FLU6 Cluster: Major facilitator superfamily MFS_1 pre... 54 1e-05
UniRef50_Q12IY6 Cluster: Major facilitator superfamily MFS_1; n=... 53 1e-05
UniRef50_Q0RV66 Cluster: Multidrug resistance transporter, MFS s... 53 1e-05
UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC... 53 2e-05
UniRef50_UPI0000499E89 Cluster: major facilitator superfamily pr... 53 2e-05
UniRef50_Q3E4I1 Cluster: Drug resistance transporter EmrB/QacA s... 53 2e-05
UniRef50_A7ICD9 Cluster: Major facilitator superfamily MFS_1; n=... 53 2e-05
UniRef50_A0UZW0 Cluster: Drug resistance transporter, EmrB/QacA ... 53 2e-05
UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1; ... 53 2e-05
UniRef50_Q8YRR2 Cluster: Alr3381 protein; n=2; Nostocaceae|Rep: ... 52 3e-05
UniRef50_Q1AYE3 Cluster: Drug resistance transporter EmrB/QacA s... 52 3e-05
UniRef50_A4JV49 Cluster: Major facilitator superfamily MFS_1; n=... 52 3e-05
UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella ve... 52 3e-05
UniRef50_Q5KJI9 Cluster: Putative uncharacterized protein; n=1; ... 52 3e-05
UniRef50_UPI0000E48DE8 Cluster: PREDICTED: similar to MGC80576 p... 52 3e-05
UniRef50_Q9RXQ1 Cluster: Multidrug-efflux transporter, putative;... 52 4e-05
UniRef50_Q2B8D0 Cluster: Major facilitator family transporter; n... 52 4e-05
UniRef50_Q0S4G7 Cluster: Multidrug transporter, MFS superfamily ... 51 6e-05
UniRef50_Q5AX13 Cluster: Putative uncharacterized protein; n=1; ... 51 6e-05
UniRef50_Q0U5D5 Cluster: Putative uncharacterized protein; n=1; ... 51 6e-05
UniRef50_Q4S0N3 Cluster: Chromosome 2 SCAF14781, whole genome sh... 51 8e-05
UniRef50_Q62FE5 Cluster: Major facilitator family transporter; n... 51 8e-05
UniRef50_Q3ZXW4 Cluster: Major facilitator family transporter; n... 51 8e-05
UniRef50_Q2S940 Cluster: Permease of the major facilitator super... 51 8e-05
UniRef50_Q2BPI0 Cluster: Probable NreB protein; n=1; Neptuniibac... 51 8e-05
UniRef50_Q83CB9 Cluster: Multidrug transporter, putative; n=5; C... 50 1e-04
UniRef50_Q7M899 Cluster: MULTIDRUG-EFFLUX TRANSPORTER; n=2; Heli... 50 1e-04
UniRef50_Q121X9 Cluster: Major facilitator superfamily MFS_1 pre... 50 1e-04
UniRef50_A1W636 Cluster: Major facilitator superfamily MFS_1; n=... 50 1e-04
UniRef50_Q7XA81 Cluster: At2g16980; n=7; Arabidopsis thaliana|Re... 50 1e-04
UniRef50_Q0CD81 Cluster: Predicted protein; n=6; Trichocomaceae|... 50 1e-04
UniRef50_Q8DGS3 Cluster: Tlr2241 protein; n=1; Synechococcus elo... 50 1e-04
UniRef50_Q81S21 Cluster: Major facilitator family transporter; n... 50 1e-04
UniRef50_Q3A1Q0 Cluster: Putative transport protein; n=1; Peloba... 50 1e-04
UniRef50_A0ILD1 Cluster: Drug resistance transporter, EmrB/QacA ... 50 1e-04
UniRef50_Q16VM5 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R... 50 1e-04
UniRef50_Q0E8E1 Cluster: CG32158-PC, isoform C; n=5; Endopterygo... 50 1e-04
UniRef50_Q97WR9 Cluster: Multidrug resistance protein; n=6; Sulf... 50 1e-04
UniRef50_O28265 Cluster: Sugar transporter, putative; n=1; Archa... 50 1e-04
UniRef50_A4G090 Cluster: Major facilitator superfamily MFS_1; n=... 50 1e-04
UniRef50_Q9ZBJ1 Cluster: Putative efflux protein; n=3; Streptomy... 50 2e-04
UniRef50_Q8NTC7 Cluster: Permeases of the major facilitator supe... 50 2e-04
UniRef50_Q81KN5 Cluster: Drug resistance transporter, EmrB/QacA ... 50 2e-04
UniRef50_Q9ZF64 Cluster: Multidrug-efflux transporter; n=17; Cam... 50 2e-04
UniRef50_Q1AS00 Cluster: Major facilitator superfamily MFS_1; n=... 50 2e-04
UniRef50_Q04DH7 Cluster: Permease of the major facilitator super... 50 2e-04
UniRef50_A0W4A2 Cluster: Major facilitator superfamily MFS_1 pre... 50 2e-04
UniRef50_Q5WG02 Cluster: Multidrug-efflux transporter; n=1; Baci... 49 2e-04
UniRef50_A0H326 Cluster: Major facilitator superfamily MFS_1; n=... 49 2e-04
UniRef50_Q19296 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04
UniRef50_Q9UYY0 Cluster: Multidrug resistance protein; n=4; Ther... 49 2e-04
UniRef50_Q4J724 Cluster: Drug transporter; n=1; Sulfolobus acido... 49 2e-04
UniRef50_Q3SA88 Cluster: Permease of the major facilitator super... 49 2e-04
UniRef50_A1RZ13 Cluster: Major facilitator superfamily MFS_1; n=... 49 2e-04
UniRef50_O25793 Cluster: Multidrug-efflux transporter; n=4; Heli... 49 3e-04
UniRef50_Q2BLG1 Cluster: Major facilitator family transporter; n... 49 3e-04
UniRef50_A6CVR9 Cluster: Putative nucleoside transporter YegT; n... 49 3e-04
UniRef50_A5WGZ2 Cluster: Major facilitator superfamily MFS_1; n=... 49 3e-04
UniRef50_A0YM33 Cluster: General substrate transporter; n=4; Cya... 49 3e-04
UniRef50_A0JU53 Cluster: Drug resistance transporter, EmrB/QacA ... 49 3e-04
UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R... 49 3e-04
UniRef50_Q4ZU97 Cluster: Major facilitator superfamily; n=11; Ba... 48 4e-04
UniRef50_Q41AH9 Cluster: Major facilitator superfamily MFS_1; n=... 48 4e-04
UniRef50_O66181 Cluster: Transporter; n=1; Arthrobacter sp.|Rep:... 48 4e-04
UniRef50_A6CHD2 Cluster: Major facilitator family transporter; n... 48 4e-04
UniRef50_A4T052 Cluster: Major facilitator superfamily MFS_1 pre... 48 4e-04
UniRef50_A3TZ27 Cluster: Drug resistance transporter, EmrB/QacA ... 48 4e-04
UniRef50_P32369 Cluster: Bile acid transporter; n=2; Clostridium... 48 4e-04
UniRef50_Q9JYR7 Cluster: Drug resistance translocase family prot... 48 5e-04
UniRef50_Q81MN1 Cluster: Drug resistance transporter, EmrB/QacA ... 48 5e-04
UniRef50_Q2W6Q6 Cluster: Permease of the major facilitator super... 48 5e-04
UniRef50_Q41DG4 Cluster: General substrate transporter:Major fac... 48 5e-04
UniRef50_Q1MQW7 Cluster: Permeases of the major facilitator supe... 48 5e-04
UniRef50_A5FB16 Cluster: Major facilitator superfamily MFS_1 pre... 48 5e-04
UniRef50_A3XKG1 Cluster: Multidrug-efflux transporter; n=2; Flav... 48 5e-04
UniRef50_A3VM32 Cluster: Putative multidrug-efflux transporter; ... 48 5e-04
UniRef50_Q8ZT99 Cluster: Antibiotic resistance (Efflux) protein,... 48 5e-04
UniRef50_Q0W2N8 Cluster: Putative permease; n=1; uncultured meth... 48 5e-04
UniRef50_A3CTZ3 Cluster: Drug resistance transporter, EmrB/QacA ... 48 5e-04
UniRef50_Q89AA9 Cluster: Uncharacterized transporter bbp_411; n=... 48 5e-04
UniRef50_UPI000023D3EA Cluster: hypothetical protein FG09806.1; ... 48 7e-04
UniRef50_UPI000023D2E5 Cluster: hypothetical protein FG07134.1; ... 48 7e-04
UniRef50_Q89RK7 Cluster: Blr2756 protein; n=11; Rhizobiales|Rep:... 48 7e-04
UniRef50_Q5QWC0 Cluster: Permease of the major facilitator super... 48 7e-04
UniRef50_Q4UMZ5 Cluster: Bicyclomycin resistance protein; n=9; R... 48 7e-04
UniRef50_Q0EXF3 Cluster: Drug resistance transporter Bcr/CflA su... 48 7e-04
UniRef50_A6PBP7 Cluster: Drug resistance transporter, Bcr/CflA s... 48 7e-04
UniRef50_Q86M88 Cluster: ComD; n=2; Dictyostelium discoideum|Rep... 48 7e-04
UniRef50_Q97TH0 Cluster: Permease, MDR related; n=5; Clostridial... 47 0.001
UniRef50_Q926U1 Cluster: Lin2949 protein; n=12; Listeria|Rep: Li... 47 0.001
UniRef50_Q7MZM7 Cluster: Similar to bicyclomycin resistance prot... 47 0.001
UniRef50_Q2T8K3 Cluster: Drug resistance transporter, EmrB/QacA ... 47 0.001
UniRef50_A6UIH2 Cluster: Major facilitator superfamily MFS_1 pre... 47 0.001
UniRef50_A5US69 Cluster: Major facilitator superfamily MFS_1 pre... 47 0.001
UniRef50_A4L2N9 Cluster: Permease; n=10; Lactobacillus|Rep: Perm... 47 0.001
UniRef50_A3QCW6 Cluster: Major facilitator superfamily MFS_1; n=... 47 0.001
UniRef50_A1AWF8 Cluster: Major facilitator superfamily MFS_1 pre... 47 0.001
UniRef50_A7S9D8 Cluster: Predicted protein; n=1; Nematostella ve... 47 0.001
UniRef50_A1CI39 Cluster: MFS transporter, putative; n=5; Trichoc... 47 0.001
UniRef50_Q8U4E5 Cluster: Quinolone resistance protein norA homol... 47 0.001
UniRef50_P0A4K4 Cluster: Multi-drug resistance efflux pump pmrA;... 47 0.001
UniRef50_UPI0000F51781 Cluster: hypothetical protein Faci_030003... 47 0.001
UniRef50_UPI0000D573B2 Cluster: PREDICTED: similar to tumor supp... 47 0.001
UniRef50_UPI000023D093 Cluster: hypothetical protein FG02457.1; ... 47 0.001
UniRef50_Q9PEN5 Cluster: Drug:proton antiporter; n=14; Bacteria|... 47 0.001
UniRef50_Q62KW2 Cluster: Fosmidomycin resistance protein; n=19; ... 47 0.001
UniRef50_Q2JF41 Cluster: Drug resistance transporter EmrB/QacA s... 47 0.001
UniRef50_Q0K358 Cluster: Arabinose efflux permease; n=1; Ralston... 47 0.001
UniRef50_A3I9G6 Cluster: Multidrug-efflux transporter; n=1; Baci... 47 0.001
UniRef50_A3EQV7 Cluster: Permease of the major facilitator super... 47 0.001
UniRef50_A7SHN9 Cluster: Predicted protein; n=2; Nematostella ve... 47 0.001
UniRef50_A4VCK6 Cluster: IP12904p; n=5; Diptera|Rep: IP12904p - ... 47 0.001
UniRef50_Q2UQA7 Cluster: Predicted transporter; n=1; Aspergillus... 47 0.001
UniRef50_Q2GPY7 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001
UniRef50_Q3K7N8 Cluster: Drug resistance transporter EmrB/QacA s... 46 0.002
UniRef50_Q4IWN9 Cluster: General substrate transporter; n=10; Pr... 46 0.002
UniRef50_Q21DL0 Cluster: Major facilitator superfamily MFS_1; n=... 46 0.002
UniRef50_Q1R0S4 Cluster: Major facilitator superfamily MFS_1; n=... 46 0.002
UniRef50_Q0A500 Cluster: Major facilitator superfamily MFS_1; n=... 46 0.002
UniRef50_A3IGE2 Cluster: Chloramphenicol resistance protein; n=1... 46 0.002
UniRef50_Q6C8F0 Cluster: Similar to tr|Q96TW4 Hansenula anomala ... 46 0.002
UniRef50_A6QZZ8 Cluster: Predicted protein; n=2; Onygenales|Rep:... 46 0.002
UniRef50_P42432 Cluster: Nitrate transporter; n=2; Bacillus|Rep:... 46 0.002
UniRef50_UPI00015B420B Cluster: PREDICTED: similar to adenylate ... 46 0.002
UniRef50_Q32LS0 Cluster: Zgc:123168; n=9; Euteleostomi|Rep: Zgc:... 46 0.002
UniRef50_Q9KG75 Cluster: Multidrug-efflux transporter; n=1; Baci... 46 0.002
UniRef50_Q81VG2 Cluster: Major facilitator family transporter; n... 46 0.002
UniRef50_Q2S1S4 Cluster: Transporter, major facilitator family; ... 46 0.002
UniRef50_A1ETT9 Cluster: Transporter, putative, degenerate; n=2;... 46 0.002
UniRef50_A0Y7U4 Cluster: Multidrug-efflux transporter; n=1; mari... 46 0.002
UniRef50_Q4DHV3 Cluster: Putative uncharacterized protein; n=2; ... 46 0.002
UniRef50_A7SCJ0 Cluster: Predicted protein; n=2; Nematostella ve... 46 0.002
UniRef50_A4RIR5 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_Q8DTP7 Cluster: Putative permease; multidrug efflux pro... 46 0.003
UniRef50_Q6CYR8 Cluster: MFS efflux transporter; n=4; Gammaprote... 46 0.003
UniRef50_Q5KW08 Cluster: Multidrug resistance protein; n=2; Geob... 46 0.003
UniRef50_Q2B5E8 Cluster: YxiO; n=4; Bacillus|Rep: YxiO - Bacillu... 46 0.003
UniRef50_Q1QFP1 Cluster: Major facilitator superfamily MFS_1; n=... 46 0.003
UniRef50_Q03I48 Cluster: Permease of the major facilitator super... 46 0.003
UniRef50_A5UW78 Cluster: Drug resistance transporter, EmrB/QacA ... 46 0.003
UniRef50_A3UH39 Cluster: Multidrug resistance protein, putative;... 46 0.003
UniRef50_A2U870 Cluster: Drug resistance transporter, EmrB/QacA ... 46 0.003
UniRef50_A0LEE5 Cluster: Major facilitator superfamily MFS_1; n=... 46 0.003
UniRef50_Q17KH3 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R... 46 0.003
UniRef50_Q5AT20 Cluster: Putative uncharacterized protein; n=2; ... 46 0.003
UniRef50_A6R1F2 Cluster: Predicted protein; n=1; Ajellomyces cap... 46 0.003
UniRef50_P77726 Cluster: Inner membrane transport protein yajR; ... 46 0.003
UniRef50_P59845 Cluster: Probable vesicular acetylcholine transp... 46 0.003
UniRef50_UPI0000D56A3C Cluster: PREDICTED: similar to CG15890-PA... 45 0.004
UniRef50_Q7NUB4 Cluster: Probable MFS metabolite transporter; n=... 45 0.004
UniRef50_Q2JNV3 Cluster: Transporter, drug:H+ antiporter-1 (12 s... 45 0.004
UniRef50_P73784 Cluster: Quinolene resistance protein; NorA; n=1... 45 0.004
UniRef50_Q3VZ12 Cluster: Major facilitator superfamily; n=1; Fra... 45 0.004
UniRef50_Q28R19 Cluster: Major facilitator superfamily MFS_1; n=... 45 0.004
UniRef50_A4FBP3 Cluster: Putative multidrug resistance protein; ... 45 0.004
UniRef50_A0DCT4 Cluster: Chromosome undetermined scaffold_46, wh... 45 0.004
UniRef50_A4R590 Cluster: Putative uncharacterized protein; n=2; ... 45 0.004
UniRef50_Q00538 Cluster: Methylenomycin A resistance protein; n=... 45 0.004
UniRef50_Q8E8V1 Cluster: Drug resistance transporter, Bcr/CflA f... 45 0.005
UniRef50_Q31HA1 Cluster: Major facilitator superfamily (MFS) tra... 45 0.005
UniRef50_Q1YRM8 Cluster: Major facilitator family transporter; n... 45 0.005
UniRef50_Q03U74 Cluster: Permease of the major facilitator super... 45 0.005
UniRef50_A7BTL7 Cluster: Major facilitator family transporter; n... 45 0.005
UniRef50_A0LKW6 Cluster: Major facilitator superfamily MFS_1; n=... 45 0.005
UniRef50_A6SQG5 Cluster: Putative uncharacterized protein; n=2; ... 45 0.005
UniRef50_A5DS84 Cluster: Putative uncharacterized protein; n=2; ... 45 0.005
UniRef50_Q97BD9 Cluster: Multidrug-efflux transporter; n=4; Ther... 45 0.005
UniRef50_O28731 Cluster: Putative uncharacterized protein; n=1; ... 45 0.005
UniRef50_P54559 Cluster: Uncharacterized transporter yqjV; n=1; ... 45 0.005
UniRef50_UPI0000E87E47 Cluster: MFS family transporter; n=1; Met... 44 0.007
UniRef50_Q8JKI7 Cluster: Tetracyclin-resistance protein; n=1; He... 44 0.007
UniRef50_Q81QS2 Cluster: Major facilitator family transporter; n... 44 0.007
UniRef50_Q390I3 Cluster: Major facilitator superfamily (MFS_1) t... 44 0.007
UniRef50_Q2JMV2 Cluster: Transporter, major facilitator family; ... 44 0.007
UniRef50_Q2JC44 Cluster: Major facilitator superfamily MFS_1; n=... 44 0.007
UniRef50_A7GXA3 Cluster: Permease, MDR related, probably tetracy... 44 0.007
UniRef50_A1T011 Cluster: Transporter major facilitator superfami... 44 0.007
UniRef50_A1A1V2 Cluster: Multidrug transport protein; n=2; Bifid... 44 0.007
UniRef50_Q7XJT5 Cluster: Putative tetracycline transporter prote... 44 0.007
UniRef50_Q86K72 Cluster: Putative uncharacterized protein; n=1; ... 44 0.007
UniRef50_Q17KH2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ... 44 0.007
UniRef50_Q1DVP8 Cluster: Putative uncharacterized protein; n=1; ... 44 0.007
UniRef50_A2QB97 Cluster: Remark: alternate name for S. cerevisia... 44 0.007
UniRef50_UPI00015BCE0A Cluster: UPI00015BCE0A related cluster; n... 44 0.009
UniRef50_Q83EP3 Cluster: Major facilitator family transporter; n... 44 0.009
UniRef50_Q1DG35 Cluster: Drug resistance transporter, EmrB/QacA ... 44 0.009
UniRef50_Q0M6R4 Cluster: General substrate transporter:Major fac... 44 0.009
UniRef50_A5IHN8 Cluster: Major facilitator family transporter; n... 44 0.009
UniRef50_A4A657 Cluster: Major facilitator family transporter; n... 44 0.009
UniRef50_Q9UAZ6 Cluster: Putative uncharacterized protein Y4C6B.... 44 0.009
UniRef50_Q38DC2 Cluster: Transporter, putative; n=1; Trypanosoma... 44 0.009
UniRef50_Q7SET5 Cluster: Putative uncharacterized protein NCU007... 44 0.009
UniRef50_Q9YAM9 Cluster: Putative MFS transporter; n=1; Aeropyru... 44 0.009
UniRef50_Q477L0 Cluster: Drug resistance transporter EmrB/QacA s... 44 0.012
UniRef50_O67276 Cluster: Transporter; n=1; Aquifex aeolicus|Rep:... 44 0.012
UniRef50_Q41CM9 Cluster: Major facilitator superfamily MFS_1 pre... 44 0.012
UniRef50_Q13FE7 Cluster: Major facilitator superfamily (MFS) mul... 44 0.012
UniRef50_Q0TPZ9 Cluster: Transporter, major facilitator family; ... 44 0.012
UniRef50_A2U881 Cluster: Major facilitator superfamily MFS_1 pre... 44 0.012
UniRef50_A1SIP2 Cluster: Drug resistance transporter, EmrB/QacA ... 44 0.012
UniRef50_A1HML8 Cluster: Major facilitator superfamily MFS_1 pre... 44 0.012
UniRef50_A5K9J4 Cluster: Transporter, putative; n=6; Plasmodium|... 44 0.012
UniRef50_Q7SA93 Cluster: Putative uncharacterized protein NCU082... 44 0.012
UniRef50_UPI0000D557DF Cluster: PREDICTED: similar to CG31106-PA... 43 0.015
UniRef50_Q8KCI0 Cluster: PucC protein; n=9; Chlorobiaceae|Rep: P... 43 0.015
UniRef50_Q7NYU3 Cluster: Probable multidrug resistance protein; ... 43 0.015
UniRef50_Q5WJG0 Cluster: Major facilitator (MFS) superfamily pro... 43 0.015
UniRef50_Q0LKG1 Cluster: Drug resistance transporter EmrB/QacA s... 43 0.015
UniRef50_A5W8J8 Cluster: Drug resistance transporter, EmrB/QacA ... 43 0.015
UniRef50_A4XC85 Cluster: Major facilitator superfamily MFS_1; n=... 43 0.015
UniRef50_Q0UV31 Cluster: Putative uncharacterized protein; n=2; ... 43 0.015
UniRef50_Q8U2Y1 Cluster: Multidrug resistance protein; n=1; Pyro... 43 0.015
UniRef50_Q0W6V9 Cluster: Putative permease; n=1; uncultured meth... 43 0.015
UniRef50_Q8K999 Cluster: Uncharacterized transporter BUsg_450; n... 43 0.015
UniRef50_UPI0000F20440 Cluster: PREDICTED: hypothetical protein;... 43 0.020
UniRef50_Q98M07 Cluster: Probable membrane transport protein; n=... 43 0.020
UniRef50_Q987Z4 Cluster: Mlr6842 protein; n=1; Mesorhizobium lot... 43 0.020
UniRef50_Q74F57 Cluster: Transporter, putative; n=7; Bacteria|Re... 43 0.020
UniRef50_Q73TH9 Cluster: Putative uncharacterized protein; n=1; ... 43 0.020
UniRef50_Q65FX6 Cluster: YttB; n=2; Bacillus|Rep: YttB - Bacillu... 43 0.020
UniRef50_Q2K7G2 Cluster: Putative multidrug resistance transport... 43 0.020
UniRef50_Q12EW1 Cluster: Major facilitator superfamily MFS_1; n=... 43 0.020
UniRef50_Q0HZC0 Cluster: Major facilitator superfamily MFS_1; n=... 43 0.020
UniRef50_Q03V51 Cluster: Permease of the major facilitator super... 43 0.020
UniRef50_A3Y6W0 Cluster: General substrate transporter:Major fac... 43 0.020
UniRef50_A7SFX7 Cluster: Predicted protein; n=2; Nematostella ve... 43 0.020
UniRef50_A4HMU7 Cluster: Putative uncharacterized protein; n=4; ... 43 0.020
UniRef50_Q4P8K9 Cluster: Putative uncharacterized protein; n=1; ... 43 0.020
UniRef50_Q83LI8 Cluster: Multidrug resistance protein mdtH; n=51... 43 0.020
UniRef50_Q9HYU1 Cluster: Probable major facilitator superfamily ... 42 0.027
UniRef50_Q67KW6 Cluster: Multidrug efflux protein; n=1; Symbioba... 42 0.027
UniRef50_Q5WLF5 Cluster: Major facilitator (MFS) superfamily mac... 42 0.027
UniRef50_Q393A2 Cluster: Major facilitator superfamily (MFS_1) t... 42 0.027
UniRef50_Q21S94 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.027
UniRef50_Q14FR6 Cluster: Multidrug resistance protein, membrane ... 42 0.027
UniRef50_Q129Q3 Cluster: Major facilitator superfamily MFS_1 pre... 42 0.027
UniRef50_Q03Z75 Cluster: Permease of the major facilitator super... 42 0.027
UniRef50_A5G198 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.027
UniRef50_A4KPJ5 Cluster: Major facilitator superfamily (MFS) tra... 42 0.027
UniRef50_A3UQ96 Cluster: Putative multidrug resistance protein; ... 42 0.027
UniRef50_Q16HW1 Cluster: Synaptic vesicle protein; n=3; Culicida... 42 0.027
UniRef50_A7SJM3 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.027
UniRef50_A0D579 Cluster: Chromosome undetermined scaffold_38, wh... 42 0.027
UniRef50_Q0D153 Cluster: Predicted protein; n=1; Aspergillus ter... 42 0.027
UniRef50_A6S2I2 Cluster: Putative uncharacterized protein; n=2; ... 42 0.027
UniRef50_Q97Y15 Cluster: Multidrug resistance transporter relate... 42 0.027
UniRef50_A2SQ54 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.027
UniRef50_UPI00015973D7 Cluster: YfiU; n=1; Bacillus amyloliquefa... 42 0.036
UniRef50_UPI0000DB7E26 Cluster: PREDICTED: similar to CG30345-PA... 42 0.036
UniRef50_Q6HGQ1 Cluster: Permease; n=2; Bacillaceae|Rep: Permeas... 42 0.036
UniRef50_Q6AM35 Cluster: Related to efflux pump antibiotic resis... 42 0.036
UniRef50_Q5L1F8 Cluster: Multidrug resistance protein; n=18; Bac... 42 0.036
UniRef50_Q39MF3 Cluster: Major facilitator superfamily (MFS_1) t... 42 0.036
UniRef50_A6W0F9 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.036
UniRef50_A6FZG2 Cluster: Major facilitator superfamily protein; ... 42 0.036
UniRef50_A5LCD7 Cluster: Dephospho-CoA kinase; n=2; Streptococcu... 42 0.036
UniRef50_A3JJB0 Cluster: Transport protein; n=2; Marinobacter|Re... 42 0.036
UniRef50_A1FT48 Cluster: Major facilitator superfamily MFS_1 pre... 42 0.036
UniRef50_A5DS14 Cluster: Putative uncharacterized protein; n=1; ... 42 0.036
UniRef50_A2Q8E9 Cluster: Function: mdr of B. subtilis is a multi... 42 0.036
UniRef50_Q6L2Q5 Cluster: Permease; n=2; Thermoplasmatales|Rep: P... 42 0.036
UniRef50_O28944 Cluster: Multidrug resistance protein; n=1; Arch... 42 0.036
UniRef50_Q8ZS83 Cluster: Nickel resistance protein; n=2; Cyanoba... 42 0.047
UniRef50_Q89NG1 Cluster: Major facilitator superfamily transport... 42 0.047
UniRef50_Q88T41 Cluster: Transport protein; n=1; Lactobacillus p... 42 0.047
UniRef50_Q7VRH7 Cluster: MFS family transporter; n=2; Candidatus... 42 0.047
UniRef50_Q64SV1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.047
UniRef50_Q2J981 Cluster: General substrate transporter; n=2; Act... 42 0.047
UniRef50_Q56175 Cluster: ORF4; putative; n=2; Streptomyces viola... 42 0.047
UniRef50_Q1IP19 Cluster: Major facilitator superfamily (MFS) tra... 42 0.047
UniRef50_Q0LNF5 Cluster: Major facilitator superfamily MFS_1 pre... 42 0.047
UniRef50_Q0FFS7 Cluster: Drug resistance transporter, Bcr/CflA f... 42 0.047
UniRef50_A6CVH7 Cluster: Drug resistance transporter, Bcr/CflA f... 42 0.047
UniRef50_A3YHL5 Cluster: Drug resistance transporter, Bcr/CflA f... 42 0.047
UniRef50_A1ZFX4 Cluster: Major facilitator family transporter; n... 42 0.047
UniRef50_A1HQS7 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.047
UniRef50_A0W9Y1 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.047
UniRef50_A0QGI1 Cluster: Drug transporter; n=7; Actinomycetales|... 42 0.047
UniRef50_A0LFP9 Cluster: Major facilitator superfamily MFS_1; n=... 42 0.047
UniRef50_Q7PUS2 Cluster: ENSANGP00000018326; n=1; Anopheles gamb... 42 0.047
UniRef50_Q7S9Y0 Cluster: Putative uncharacterized protein NCU079... 42 0.047
UniRef50_Q5KLU8 Cluster: AE016780 membrane protein, putative, pu... 42 0.047
UniRef50_Q2UFI2 Cluster: Predicted transporter; n=1; Aspergillus... 42 0.047
UniRef50_A2QKN9 Cluster: Contig An05c0040, complete genome; n=11... 42 0.047
UniRef50_Q8TK34 Cluster: Multidrug resistance efflux pump; n=1; ... 42 0.047
UniRef50_Q9RZ93 Cluster: Drug transport protein, putative; n=2; ... 41 0.062
UniRef50_Q98B83 Cluster: Mll5688 protein; n=1; Mesorhizobium lot... 41 0.062
UniRef50_Q8YUW6 Cluster: Alr2215 protein; n=5; Cyanobacteria|Rep... 41 0.062
UniRef50_Q7VH58 Cluster: Putative uncharacterized protein; n=1; ... 41 0.062
UniRef50_Q2SDT3 Cluster: Permease of the major facilitator super... 41 0.062
UniRef50_Q2AEQ4 Cluster: Major facilitator superfamily MFS_1; n=... 41 0.062
UniRef50_Q18S15 Cluster: Major facilitator superfamily MFS_1 pre... 41 0.062
UniRef50_A6VVD4 Cluster: Major facilitator superfamily MFS_1; n=... 41 0.062
UniRef50_A4G8F6 Cluster: Bicyclomycin resistance protein; n=3; B... 41 0.062
UniRef50_Q9VYV0 Cluster: CG15221-PA; n=3; Sophophora|Rep: CG1522... 41 0.062
UniRef50_Q961H2 Cluster: GH23453p; n=5; Sophophora|Rep: GH23453p... 41 0.062
UniRef50_Q7KV86 Cluster: CG33234-PA; n=2; Drosophila melanogaste... 41 0.062
UniRef50_A1Z7R6 Cluster: CG8046-PA, isoform A; n=5; Sophophora|R... 41 0.062
UniRef50_Q6CDF9 Cluster: Similar to DEHA0A10670g Debaryomyces ha... 41 0.062
UniRef50_Q6BY36 Cluster: Debaryomyces hansenii chromosome A of s... 41 0.062
UniRef50_Q0W4M4 Cluster: Multidrug resistance transport system, ... 41 0.062
UniRef50_A4YDI7 Cluster: Major facilitator superfamily MFS_1; n=... 41 0.062
UniRef50_Q9CJ52 Cluster: Transporter; n=2; Lactococcus lactis|Re... 41 0.083
UniRef50_Q8Y8C7 Cluster: Lmo0981 protein; n=10; Listeria|Rep: Lm... 41 0.083
UniRef50_Q7VGQ3 Cluster: Putative uncharacterized protein; n=1; ... 41 0.083
UniRef50_Q5LQP3 Cluster: Drug resistance transporter, Bcr/CflA s... 41 0.083
UniRef50_Q5GSS7 Cluster: Permease of the major facilitator super... 41 0.083
UniRef50_Q4JSH4 Cluster: Putative permease of the major facilita... 41 0.083
UniRef50_Q3ZW08 Cluster: Major facilitator family transporter; n... 41 0.083
UniRef50_Q0H2V8 Cluster: Putative transmembrane efflux protein; ... 41 0.083
UniRef50_Q03CN7 Cluster: Permease of the major facilitator super... 41 0.083
UniRef50_Q03BY7 Cluster: Permease of the major facilitator super... 41 0.083
UniRef50_A6LYN3 Cluster: Drug resistance transporter, EmrB/QacA ... 41 0.083
UniRef50_A5KS25 Cluster: Major facilitator superfamily MFS_1 pre... 41 0.083
UniRef50_A4X1R9 Cluster: Major facilitator superfamily MFS_1; n=... 41 0.083
UniRef50_A4TNN5 Cluster: Putative uncharacterized protein precur... 41 0.083
UniRef50_A3IGH0 Cluster: Antibiotic resistance protein; n=1; Bac... 41 0.083
UniRef50_A3I6W0 Cluster: Blt; n=1; Bacillus sp. B14905|Rep: Blt ... 41 0.083
UniRef50_A3ET83 Cluster: Permease of the major facilitator super... 41 0.083
UniRef50_A0K253 Cluster: Drug resistance transporter, EmrB/QacA ... 41 0.083
UniRef50_Q16WK6 Cluster: Putative uncharacterized protein; n=3; ... 41 0.083
UniRef50_Q5A6P6 Cluster: Potential quinidine/multidrug transport... 41 0.083
UniRef50_Q0UAH6 Cluster: Putative uncharacterized protein; n=1; ... 41 0.083
UniRef50_Q0C9A2 Cluster: Predicted protein; n=1; Aspergillus ter... 41 0.083
UniRef50_Q97BG6 Cluster: Multidrug resistance protein; n=4; Ther... 41 0.083
UniRef50_Q9RTL7 Cluster: Fosmidomycin resistance protein, putati... 40 0.11
UniRef50_Q6ACE4 Cluster: Albicidin efflux pump; n=1; Leifsonia x... 40 0.11
UniRef50_Q47P50 Cluster: Drug resistance transporter Bcr/CflA su... 40 0.11
>UniRef50_Q5SR56 Cluster: Hippocampus abundant transcript-like
protein 1; n=66; Eumetazoa|Rep: Hippocampus abundant
transcript-like protein 1 - Homo sapiens (Human)
Length = 485
Score = 578 bits (1426), Expect = e-163
Identities = 269/419 (64%), Positives = 329/419 (78%), Gaps = 1/419 (0%)
Query: 25 GIMTMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGIL 84
G + G G PSV+HA +VIFLEFFAWGLLT P+++VL+ TF HTFLMNGLI G+KG+L
Sbjct: 12 GSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLL 71
Query: 85 SFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVF 144
SFLSAPLIGALSDVWGRK FLL TVFFTC PIPLM I+ WW+FAMIS+SGVF+VTFS++F
Sbjct: 72 SFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIF 131
Query: 145 AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFF 204
AYVADVT E ERS AYG VSATFAASLV SPA+GAYL YG+SL F
Sbjct: 132 AYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICF 191
Query: 205 IMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQY 264
I+VAVPESLPEK+RP WG ISW+QADPFA+L+KVG + TVL++C+ VFLSYLPEAGQY
Sbjct: 192 ILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQY 251
Query: 265 SCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQ 323
S F+YL+ V+GFG V++A FIA+VG+LSI Q L LM+SLG K+T+++GL F+MLQ
Sbjct: 252 SSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQ 311
Query: 324 LMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGL 383
L WYGFGS+ WMMWAAG +AA+ SIT+PAISA VS N+ +D+QGV QG++TG+RGLCNGL
Sbjct: 312 LAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGL 371
Query: 384 GPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLVTAFLPE 442
GPA++G IFY+FHV+L E K ++PGPPF+ GA +V+ + LV F+PE
Sbjct: 372 GPALYGFIFYMFHVELTELGPKLNSNNVPLQGAVIPGPPFLFGACIVLMSFLVALFIPE 430
>UniRef50_UPI0000E4722E Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 530
Score = 547 bits (1350), Expect = e-154
Identities = 253/388 (65%), Positives = 312/388 (80%), Gaps = 3/388 (0%)
Query: 14 VIRNRKTVMKDGIMTMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLM 73
+IR KDG T GIGEPS++HAL++IFLEFF+WGLLT P+++VL+ TFP+HTFLM
Sbjct: 10 LIRTSSKQRKDGGRT--GIGEPSLYHALIIIFLEFFSWGLLTTPMLTVLHETFPEHTFLM 67
Query: 74 NGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISIS 133
NGL+ G+KG L+FLSAP++GALSDVWGRK FLL+TVFFTC PIPLM I+ WWFFAM+S+S
Sbjct: 68 NGLVQGVKGFLAFLSAPMLGALSDVWGRKSFLLLTVFFTCMPIPLMKISAWWFFAMLSVS 127
Query: 134 GVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXX 193
GV +VTFS++FAYVAD+T ++ERS+AYGLVSATFAASL+ SPALGAYL +YG+
Sbjct: 128 GVMSVTFSLIFAYVADITPDSERSQAYGLVSATFAASLITSPALGAYLASIYGDGFVVFL 187
Query: 194 XXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAV 253
FI+VAVPESLPEKVR WG I+WEQADPF +LRK G + TVL+LC+AV
Sbjct: 188 ATAIALCDVLFILVAVPESLPEKVRRASWGASITWEQADPFTSLRKAGQDYTVLLLCIAV 247
Query: 254 FLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHT 312
FLSYLPEAGQYSC+F+YL+ V F +V +IA+VGVLS+ Q ++LGFL+K LG KHT
Sbjct: 248 FLSYLPEAGQYSCMFLYLRTVGKFSPPEVPAYIALVGVLSVFTQTILLGFLIKHLGHKHT 307
Query: 313 IMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGM 372
IMVGL EML+LMWYGF S+ WMMWAAGV+A++ SI +PAISA +S + D+QGVVQGM
Sbjct: 308 IMVGLTCEMLELMWYGFASQQWMMWAAGVIASVCSINFPAISAMISHCADQDKQGVVQGM 367
Query: 373 VTGVRGLCNGLGPAMFGVIFYLFHVDLN 400
VTG+R LC GLGPA+FGVIFY F V+L+
Sbjct: 368 VTGIRSLCTGLGPALFGVIFYFFDVNLD 395
Score = 40.3 bits (90), Expect = 0.11
Identities = 17/25 (68%), Positives = 21/25 (84%)
Query: 417 LVPGPPFVLGALLVICALLVTAFLP 441
++PGPPFV G+LLVI +LLV FLP
Sbjct: 456 IMPGPPFVFGSLLVIISLLVAYFLP 480
>UniRef50_UPI00002053B2 Cluster: PREDICTED: hippocampus abundant
transcript 1 isoform 1; n=3; Eutheria|Rep: PREDICTED:
hippocampus abundant transcript 1 isoform 1 - Pan
troglodytes
Length = 466
Score = 544 bits (1343), Expect = e-153
Identities = 271/459 (59%), Positives = 336/459 (73%), Gaps = 34/459 (7%)
Query: 1 MTPTKTTKTEVEM-VIRNRKTVMKDGIMTMSGIGEPSVFHALVVIFLEFFAWGLLTMPII 59
MT K K ++ +K ++KDG T GIG PSV+HA++VIFLEFFAWGLLT P +
Sbjct: 1 MTQGKKKKRAANRSIMLAKKIIIKDG-GTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTL 59
Query: 60 SVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLM 119
VL+ TFP HTFLMNGLI G+KG+LSFLSAPLIGALSDVWGRK FLL+TVFFTCAPIPLM
Sbjct: 60 VVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLM 119
Query: 120 TINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGA 179
I+ WW+FA+IS+SGVFAVTFS+VFAYVAD+T E ERS AYGLVSATFAASLV SPA+GA
Sbjct: 120 KISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGA 179
Query: 180 YLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRK 239
YL +YG+SL FI+VAVPESLPEK+RP WG ISWEQADPFA+L+K
Sbjct: 180 YLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKK 239
Query: 240 VGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVI 299
VG + VL++C+ VFLSYLPEAGQYS F+YL+ ++
Sbjct: 240 VGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQT-----------------------IV 276
Query: 300 LGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSV 359
L LM+S+G K+TI++GL F++LQL WYGFGS WMMWAAG +AA+ SIT+PA+SA VS
Sbjct: 277 LSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSR 336
Query: 360 NSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLNE--------GHNKTGRIPE 411
+ AD+QGVVQGM+TG+RGLCNGLGPA++G IFY+FHV+L E G N + +
Sbjct: 337 TADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGTDLGTNTSPQHHF 396
Query: 412 ERHALLVPGPPFVLGALLVICALLVTAFLPEEDSNGRRA 450
E+++ ++PGPPF+ GA V+ ALLV F+PE + R+
Sbjct: 397 EQNS-IIPGPPFLFGACSVLLALLVALFIPEHTNLSLRS 434
>UniRef50_Q965I9 Cluster: Putative uncharacterized protein T25D3.4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T25D3.4 - Caenorhabditis elegans
Length = 550
Score = 486 bits (1198), Expect = e-136
Identities = 241/444 (54%), Positives = 316/444 (71%), Gaps = 37/444 (8%)
Query: 34 EPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIG 93
E SV HALVVIFLE+FAWGLLT+P+I+VL TFP + FLMNGL++G+KG+LSFLSAPL+G
Sbjct: 72 EASVSHALVVIFLEYFAWGLLTVPVINVLAETFPTNKFLMNGLVLGVKGLLSFLSAPLVG 131
Query: 94 ALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTE 153
ALSDVWGRK FL++TV TC PIP + I+ WW+F++ S+SG+F+VTFS++ AYVAD+T +
Sbjct: 132 ALSDVWGRKAFLILTVLCTCMPIPCLKISPWWYFSLFSLSGLFSVTFSVILAYVADITDK 191
Query: 154 AERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL 213
+ERS AYGLVSATFAASLV SPALGAY+ ++YG+SL FI++ VPESL
Sbjct: 192 SERSSAYGLVSATFAASLVTSPALGAYISEVYGDSLVVLLATIVSVADVIFIVLFVPESL 251
Query: 214 PEKVRPTGW------GPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCI 267
P + R TG V +W+ ADPF +LR V ++ VL L VFLSYLPE+GQ+SC
Sbjct: 252 PSR-RNTGSVSQITPNEVFNWQSADPFGSLRIVWEDKLVLQLATIVFLSYLPESGQFSCF 310
Query: 268 FVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
FVYLKLV+GF VA++I +VG+LS+ Q L L G KHTI +GL+F+++QL W
Sbjct: 311 FVYLKLVVGFSPEAVAMYIGLVGILSVVAQTGFLHCLTSRFGTKHTITLGLIFQLIQLTW 370
Query: 327 YGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPA 386
YG G++ WMMW+AGVLAA+ SITYP+ISA+VS+ S D+QG VQG++TG+RGLC G GPA
Sbjct: 371 YGLGTQYWMMWSAGVLAAMSSITYPSISAFVSILSDKDKQGTVQGVITGIRGLCTGFGPA 430
Query: 387 MFGVIFYLFHVDLNEGHNKTG--------RIPE-----------------ERHAL----L 417
+FG +FYLF VDL + + G +IPE +R A
Sbjct: 431 LFGTVFYLFDVDLEDEKSTGGALSLVAPRKIPEKILAPTRNESSWIQQQVDRAAAFDWQF 490
Query: 418 VPGPPFVLGALLVICALLVTAFLP 441
+PGPPF++GA++V+ ALL+ + LP
Sbjct: 491 IPGPPFLIGAMMVLFALLINSTLP 514
>UniRef50_Q9VPE0 Cluster: CG18281-PA; n=2; Drosophila
melanogaster|Rep: CG18281-PA - Drosophila melanogaster
(Fruit fly)
Length = 542
Score = 189 bits (460), Expect = 2e-46
Identities = 84/188 (44%), Positives = 125/188 (66%)
Query: 26 IMTMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILS 85
++ SGIG+ SV+HA++V F+ +F+WGLLT+P I L+ +F + L++GL+ G++GIL
Sbjct: 14 LVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILG 73
Query: 86 FLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFA 145
F++ P++GA+SD GRK +L+ V T APIP M + +WWFFA++++S + T+S A
Sbjct: 74 FVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLA 133
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFI 205
YVAD TT RS+ YG+V+A+F A + SP+LG YLM YG + FI
Sbjct: 134 YVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFI 193
Query: 206 MVAVPESL 213
+ AVPESL
Sbjct: 194 IFAVPESL 201
Score = 140 bits (338), Expect = 1e-31
Identities = 76/217 (35%), Positives = 126/217 (58%), Gaps = 12/217 (5%)
Query: 227 SWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFI 286
S +D + LRK ++ +L++ + FLS P AG S VYLK MGF +V++ +
Sbjct: 283 SLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMML 342
Query: 287 AIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG 346
++ VL+I ++LG+++ +GAK +I +GLL +LQL ++GFG+ WM W + +LAAL
Sbjct: 343 GLLSVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALA 402
Query: 347 SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLNEGHNKT 406
+I A +A S+ + D +G V G+++G+ L G+GPA FGV+F++F D N
Sbjct: 403 TIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKNKVNSP 462
Query: 407 GRIPEERHALLVPGPPFVLGALLVICALLVTAFLPEE 443
+ PFV+ A+ V A+++T F+ +E
Sbjct: 463 ISM------------PFVISAIGVFVAIVLTGFIKKE 487
>UniRef50_Q5VZR4 Cluster: Hippocampus abundant transcript-like
protein 2; n=13; Tetrapoda|Rep: Hippocampus abundant
transcript-like protein 2 - Homo sapiens (Human)
Length = 134
Score = 157 bits (380), Expect = 8e-37
Identities = 72/98 (73%), Positives = 82/98 (83%)
Query: 25 GIMTMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGIL 84
G + G G PSV+HA +VIFLEFFAWGLLT P+++VL+ TF HTFLMNGLI G+KG+L
Sbjct: 33 GSTWLQGFGPPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLL 92
Query: 85 SFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTIN 122
SFLSAPLIGALSDVWGRK FLL TVFFTC PIPLM I+
Sbjct: 93 SFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRIS 130
>UniRef50_Q0C4X1 Cluster: Tetracycline-efflux transporter; n=1;
Hyphomonas neptunium ATCC 15444|Rep: Tetracycline-efflux
transporter - Hyphomonas neptunium (strain ATCC 15444)
Length = 417
Score = 150 bits (363), Expect = 9e-35
Identities = 104/369 (28%), Positives = 180/369 (48%), Gaps = 17/369 (4%)
Query: 33 GEPSVFHALVVIFLEFFAWGLLTMPIISVL-----NATFPDHTFLMNGLIMGIKGILSFL 87
G+ + F LV +F++ A+GL+ +P++ L N T + GL +++FL
Sbjct: 11 GKNAFFFVLVTVFIDHLAFGLI-IPVLPTLIQDLANVPASGATLWIGGLA-ATYAVMTFL 68
Query: 88 SAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFA 145
PLIGALSD +GR+ LLV++ LM + N W F +++G+ T+S A
Sbjct: 69 FGPLIGALSDKFGRRPVLLVSMAMLGLDFLLMALAPNIWILFLGRALAGISGATYSTANA 128
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFI 205
Y+AD TT ER RA+G + A+F + P +G L +L G + +
Sbjct: 129 YIADTTTPEERGRAFGFIGASFGLGFIFGPVIGGLLGEL-GPRIPFFAAVGLAFLNFLYG 187
Query: 206 MVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYS 265
+ +PESLP+ R ++ ++A+P A R V +A + +L +
Sbjct: 188 VFVLPESLPKARRRN-----LNLKRANPLGAARHFSKLPKVSWFLIASGIFFLAHTVFPA 242
Query: 266 CIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQL 324
V+ ++ + +Q+ + + +VGV + VQ ++GF++K LG+ TIM G ++ +
Sbjct: 243 TWSVHGEIRYDWSPMQIGLSLGLVGVGAATVQAGLMGFILKRLGSVRTIMFGYCVTIIAM 302
Query: 325 MWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLG 384
+ F + + +ALG +T PA +A +S + D QG +QG + + L +G
Sbjct: 303 TGFAFAGQPLFAYLIIPFSALGGVTMPAANALMSSLTPPDAQGELQGAASSLNALGMIIG 362
Query: 385 P-AMFGVIF 392
P M G +F
Sbjct: 363 PLIMSGALF 371
>UniRef50_Q89MY8 Cluster: Tetracycline resistance protein; n=7;
Bradyrhizobiaceae|Rep: Tetracycline resistance protein -
Bradyrhizobium japonicum
Length = 462
Score = 146 bits (353), Expect = 1e-33
Identities = 111/409 (27%), Positives = 199/409 (48%), Gaps = 31/409 (7%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKG----ILSFLSAPL 91
+V V I L+ A G++ MPI+ L +F D+ I G+ G ++ F+ +P+
Sbjct: 58 AVAFIFVTILLDMLALGVI-MPILPKLIESFVDNDTAHAARIFGLFGTAWALMQFVFSPV 116
Query: 92 IGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVAD 149
+GALSD +GR+ +L++ F A LM + + W F ISG+ + + S FAY+AD
Sbjct: 117 LGALSDRFGRRPVVLLSNFGLAADYVLMALAPSLVWLFIGRVISGITSASISTAFAYIAD 176
Query: 150 VTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAV 209
+T R+ +G + A F A ++ PALG L D+ L + ++ +
Sbjct: 177 ITPPERRAAIFGRIGAAFGAGFILGPALGGLLGDV-DPRLPFWASAALSFANALYGLLVL 235
Query: 210 PESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
PESL P+K P W A+P ALR + + + L V F++ + S
Sbjct: 236 PESLAPDKRAP------FRWTSANPVGALRLLRSNAMLAALSVVNFIAQVAHVVLPSTFV 289
Query: 269 VYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWY 327
+Y G+ V + +A+VG+ ++ VQ + +G ++++LG ++T+++GL + + +
Sbjct: 290 LYATYRYGWDSKTVGLTLAMVGICAMVVQGLAIGPIVRALGERNTLLLGLCCGAIGFVIF 349
Query: 328 GFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAM 387
G + W + +L I+ A+ + ++ D+QG +QG V+ + +GP +
Sbjct: 350 GAAPTGPLFWIGIPVMSLWGISGAAMQSLMTRLVAPDQQGQLQGATASVQSVSQLVGPFL 409
Query: 388 FGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVL-GALLVICALL 435
F + F F G + ++ PG PF+L GAL+V+C +
Sbjct: 410 FTLTFSYF-----IGTSAPWQL---------PGAPFLLAGALMVVCVAI 444
>UniRef50_Q28RT4 Cluster: Major facilitator superfamily MFS_1; n=16;
Bacteria|Rep: Major facilitator superfamily MFS_1 -
Jannaschia sp. (strain CCS1)
Length = 406
Score = 143 bits (346), Expect = 1e-32
Identities = 106/412 (25%), Positives = 198/412 (48%), Gaps = 31/412 (7%)
Query: 35 PSVFHALVVIFLEFFAWGLL--TMP-IISVLNATFPDHTFLMNGLIMGIKGILSFLSAPL 91
P++F L+ + ++ GL+ MP +I+ + + L GL+ ++ FL +P
Sbjct: 4 PTLF-ILITVTIDAMGIGLILPVMPDLITEVRGAGLANAALWGGLLSTTYAVMQFLCSPT 62
Query: 92 IGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVAD 149
+G LSD +GR+ LL+++ A +M++ W A ++G+ A T + AY+AD
Sbjct: 63 LGNLSDRFGRRPILLISLAVLAADYVVMSLAHTIWILIAGRIVAGIAAGTHATALAYMAD 122
Query: 150 VTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAV 209
++ +R++ +GL+SA F V+ P + A+L + + F + +
Sbjct: 123 ISPPEKRAQNFGLISAGFGIGFVLGPLVAAFLGEFDPRAPFVAAACLAAANFAFGYFI-L 181
Query: 210 PESLP-EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
PESLP ++ RP W +A+P L ++GA V +L + V L+Y Y I+
Sbjct: 182 PESLPKDRRRP------FQWRRANPAGGLLQIGALPGVRLLLM-VMLAYQIANFVYPAIW 234
Query: 269 VYL-KLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
Y + G+ + + + + G+ VQ ++ ++ LG T+ GL+ + L+
Sbjct: 235 AYYGQAAFGWTSRMIGLSLTVYGISMAVVQGGLIRLVLPRLGETRTVYWGLILNVCCLIC 294
Query: 327 YGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPA 386
YG + WM+WA ++A+G++ PA+ +S + AD+QG +QG++ + L L P
Sbjct: 295 YGLATEAWMIWALIPVSAMGAVVAPAMQGVMSRAAGADQQGELQGVLASISSLSMILSPI 354
Query: 387 MFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLVTA 438
+ F+ F + L +PG PF++ A+L+ A + A
Sbjct: 355 VMTQAFFWF--------------TRDEAILRLPGAPFLVAAVLMAGAFAIFA 392
>UniRef50_Q4RG87 Cluster: Chromosome 12 SCAF15104, whole genome
shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF15104, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 576
Score = 142 bits (343), Expect = 2e-32
Identities = 65/109 (59%), Positives = 85/109 (77%), Gaps = 1/109 (0%)
Query: 335 MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
MMWAAG +AA+ SIT+PA+SA VS + D+QGV QGM+TG+RGLCNGLGPA++G IFYL
Sbjct: 469 MMWAAGAVAAMSSITFPAVSALVSHCASPDQQGVAQGMITGIRGLCNGLGPALYGFIFYL 528
Query: 395 FHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLVTAFLPEE 443
F+V+LN+ + GR+ ++ LVPGPPF+ GA VI AL V AF+PE+
Sbjct: 529 FNVELNDLQPEAGRVQRDQ-KWLVPGPPFLFGACAVIFALFVAAFIPEQ 576
Score = 48.4 bits (110), Expect = 4e-04
Identities = 21/31 (67%), Positives = 25/31 (80%)
Query: 31 GIGEPSVFHALVVIFLEFFAWGLLTMPIISV 61
G G V HA+VVIFLEFFAWGLLT P+++V
Sbjct: 8 GRGRAKVAHAVVVIFLEFFAWGLLTTPMLTV 38
>UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1;
Pirellula sp.|Rep: Tetracycline-efflux transporter -
Rhodopirellula baltica
Length = 500
Score = 133 bits (322), Expect = 8e-30
Identities = 110/407 (27%), Positives = 188/407 (46%), Gaps = 31/407 (7%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKG----ILSFLSAPLIGALS 96
L+ + ++ A G++ +P++ L F +G+ G ++ F AP++GALS
Sbjct: 68 LLTLLIDILAIGII-IPVLPELIKEFVGGDTSRASWYVGVIGATYSLMQFFFAPVLGALS 126
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEA 154
D +GR+ +L ++F + + W F ++GV +FS AY+ADV+T+
Sbjct: 127 DRFGRRPVILASLFGLGVDFIVTGLAPTVGWLFVGRIVAGVMGASFSTANAYIADVSTQE 186
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP 214
R+R +GLV F +I PALG L ++ L + +PESLP
Sbjct: 187 TRARNFGLVGMMFGLGFIIGPALGGVLGGIH-IRLPFFVAAGLSLVNWLYGFFVLPESLP 245
Query: 215 EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLV 274
+ R + IS +P + ++ + L VA S L + G + + +
Sbjct: 246 PEKRGS-----ISLAAMNPLGTIARLRNYPMIAGLAVAFMFSSLAQRGLENVWVLSMGYR 300
Query: 275 MGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRT 333
G+ V + +A+VG+++ VQ ++ +K LG + T ++G L + YG S+
Sbjct: 301 FGWNEVTNGLTLALVGLMAAIVQGGMVRPTIKRLGERRTAVLGTCVSCLAFLGYGLASQG 360
Query: 334 WMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF--GVI 391
WM+ V +L + PAI + V+ + QG VQG +T + L N P +F G++
Sbjct: 361 WMIPCIVVFGSLAGLAGPAIQSLVAGRVSPEEQGKVQGALTSLISLTNIPAPLLFTSGLL 420
Query: 392 FYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLVTA 438
G+ + R P E PG PFV G+LL+ A++V A
Sbjct: 421 ----------GYFTSDRAPFE-----FPGAPFVFGSLLLAIAVIVLA 452
>UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1;
Bdellovibrio bacteriovorus|Rep: Tetracycline-efflux
transporter - Bdellovibrio bacteriovorus
Length = 367
Score = 131 bits (316), Expect = 5e-29
Identities = 97/358 (27%), Positives = 166/358 (46%), Gaps = 22/358 (6%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWW--FFAMISI 132
G + I ++ FL++PL+GALSD +GR+ LL+++ LM FA I
Sbjct: 16 GYFISIYALMQFLASPLLGALSDRFGRRSVLLISLLVAGFDYILMAYAPTLEILFAGRII 75
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
+G+ ++ AY+ADV+ + RS +G+V A F +I PA+G L L G
Sbjct: 76 AGLTGANITVAMAYIADVSNDENRSANFGMVGAAFGLGFIIGPAIGGLLGHL-GPEYPFL 134
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
FF + +PESLP+ +R I + +P +L V + +L L +
Sbjct: 135 VAAALNLLNFFFGLFILPESLPKNLRRK-----IDLRRTNPLYSLLGVLRSKHLLALLLV 189
Query: 253 VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKH 311
F L S +Y + G+ QV + +A+VG+LS Q + ++ G
Sbjct: 190 YFFFQLAGQTHPSIWTLYTETRYGWTTAQVGLSLAVVGLLSALAQGWLTRLVIPKFGEHR 249
Query: 312 TIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQG 371
T+++G + ++YG + WMM+A +L+A+ + PA+ + +S + QG +QG
Sbjct: 250 TVVIGAFGYAVSFIFYGMATEGWMMYAILILSAVFWTSPPALQSLISHKTPPQEQGELQG 309
Query: 372 MVTGVRGLCNGLGPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALL 429
+ + L + P + +F F + G+ T L +PG P+ GAL+
Sbjct: 310 SLVSLSSLAAIITPLVTTKLFAHF----SSGNPGT---------LYLPGAPYYFGALI 354
>UniRef50_Q9A8S0 Cluster: Tetracycline resistance protein; n=3;
Alphaproteobacteria|Rep: Tetracycline resistance protein
- Caulobacter crescentus (Caulobacter vibrioides)
Length = 586
Score = 130 bits (313), Expect = 1e-28
Identities = 98/361 (27%), Positives = 170/361 (47%), Gaps = 28/361 (7%)
Query: 82 GILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVT 139
G++ F+ +P++G LSD +GR+ +L ++F M N WW F +G+ A +
Sbjct: 232 GVMQFICSPILGLLSDRFGRRPVILTSIFGLGIDFLFMAFAPNLWWLFIGRIFNGMTAAS 291
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXX 197
FS AYVADVTT R++ +GL+ A F PALG +L D L
Sbjct: 292 FSTASAYVADVTTPENRAKGFGLMGAAFGIGFTFGPALGGWLWEFDHRAPFLVCAALALT 351
Query: 198 XXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSY 257
FF++ PESLP + R P W++A+P +L+ + ++ L FL
Sbjct: 352 NWLYGFFVL---PESLPPERRQ----PRFDWKKANPIGSLQLLRHHPGLMGLAGVGFLFQ 404
Query: 258 LPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVG 316
L S +Y+ G+ + + + G+ SI +Q ++G +K LG + +++G
Sbjct: 405 LAHNVLPSVFVLYMGFRYGWSPQTIGLTLMASGIASILIQAFVVGPAVKRLGERGVLLIG 464
Query: 317 LLFEMLQLMWYGFGSRTWMMWAAGV-LAALGSITYPAISAYVSVNSRADRQGVVQGMVTG 375
L L Y + T +++ AG+ + A + P + ++ + QG +QG
Sbjct: 465 LFAGFLGFSIYAL-APTSLLYLAGLPIFAFSGLIQPGLQGLMTRRVGPNEQGQLQGANAA 523
Query: 376 VRGLCNGLGPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALL 435
+ G+ + +GP +F +I + F V H+ T L +PG P ++ A+L++ A L
Sbjct: 524 MMGIASIIGPPLF-LIPFAFAV----RHDAT---------LHLPGLPILIAAVLMLAATL 569
Query: 436 V 436
+
Sbjct: 570 L 570
Score = 38.3 bits (85), Expect = 0.44
Identities = 22/113 (19%), Positives = 47/113 (41%)
Query: 284 IFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLA 343
+F GV+ ILG L G + I+ + + ++ F W ++ +
Sbjct: 226 LFATTWGVMQFICSPILGLLSDRFGRRPVILTSIFGLGIDFLFMAFAPNLWWLFIGRIFN 285
Query: 344 ALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFH 396
+ + ++ SAYV+ + + + G++ G+ GPA+ G ++ H
Sbjct: 286 GMTAASFSTASAYVADVTTPENRAKGFGLMGAAFGIGFTFGPALGGWLWEFDH 338
>UniRef50_A7NRD2 Cluster: Major facilitator superfamily MFS_1; n=2;
Chloroflexaceae|Rep: Major facilitator superfamily MFS_1
- Roseiflexus castenholzii DSM 13941
Length = 416
Score = 128 bits (309), Expect = 3e-28
Identities = 97/367 (26%), Positives = 173/367 (47%), Gaps = 24/367 (6%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+ +F++ +G++ + + P T + G++ G + FL P++G+LSD +GR
Sbjct: 22 LAVFVDLVGYGMIVPLLPFYVQRVAPGATLV--GILSGFYAMAQFLVGPMLGSLSDRFGR 79
Query: 102 KFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRA 159
+ L+ + T L+ I +++ I GV SI A +AD TT R+R
Sbjct: 80 RPVLIACLSGTSLAYLLLAIADSLPLLVLALFIDGVTGGNLSIAQASIADSTTPDRRARG 139
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP----- 214
GL+ A F L++ P +G ++ L S F + A+PESLP
Sbjct: 140 LGLIGAAFGLGLMVGPVIGG-VLSLTNLSAPALVASMLAFANTLFALAALPESLPPERRR 198
Query: 215 ----EKVRPTGWGPVISWEQADPFA---ALRKVGAERTVLMLCVAVFLSYLPEAGQYSCI 267
+ +P+ W V+ A+P A L ++ R VLM+ V + L++ +G YS
Sbjct: 199 LIPLDSAKPSHWSMVL--RVANPLANLIVLLRIVTIRRVLMVVVLLNLAF---SGLYSNF 253
Query: 268 FVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
++ G+G+ + A+F A VG+ ++ Q ++LG + + LG VG++ + L+
Sbjct: 254 PLFTAARFGWGMFENALFFAFVGICAVTTQGLLLGRMQRWLGDARLARVGMIVMVCALLA 313
Query: 327 YGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGP 385
G S WM++ + L A GS + PA+++ +S+ QG + G + L GP
Sbjct: 314 TGLASAAWMLYPSVGLIAFGSGLAIPALTSLLSLQVSPADQGRLMGGTAALLNLTMIAGP 373
Query: 386 AMFGVIF 392
+ G+ F
Sbjct: 374 VVAGISF 380
>UniRef50_A6U8Y2 Cluster: Major facilitator superfamily MFS_1; n=8;
Rhizobiales|Rep: Major facilitator superfamily MFS_1 -
Sinorhizobium medicae WSM419
Length = 421
Score = 128 bits (308), Expect = 4e-28
Identities = 98/366 (26%), Positives = 171/366 (46%), Gaps = 14/366 (3%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNA-TFPD--HTFLMNGLIMGIKGILSFLSAPLIG 93
+F +++FL+ ++ + S L T D + G ++ + + F APLIG
Sbjct: 11 LFLVFMILFLDIMGIAIIVPVLPSYLEELTGADVGEAAIDGGWLLLVYSAMQFFFAPLIG 70
Query: 94 ALSDVWGRKFFLLVTV--FFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVT 151
LSD +GR+ LL +V F I + + W F S++G+ +F AY+ADV+
Sbjct: 71 NLSDRFGRRPILLASVLTFAIDNLICALATSYWMLFIGRSLAGISGASFGTASAYIADVS 130
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
+ R++ +GL+ F + P +G L +L G + F+M A
Sbjct: 131 NDENRAKNFGLIGIAFGTGFALGPVIGGVLGEL-GPRVPFYGAAALSFLN--FVMGAF-- 185
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
LPE + P W +A+PF AL+++ + + + FL +L A Y ++ ++
Sbjct: 186 LLPETLDPANRRR-FEWRRANPFGALKQMRHYPGIGWVGLVFFLYWLAHA-VYPAVWSFV 243
Query: 272 KLVM-GFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
G+ Q+ + + I GV +I + ++L ++ +LG + T +GL F L + Y
Sbjct: 244 ASYRYGWSEGQIGLSLGIFGVGGAIVMALVLPRVVPALGERRTAALGLTFTALGMAGYAA 303
Query: 330 GSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
WM++A V AL S+ P + + SV+ QG +QG +T + + +GP MF
Sbjct: 304 AWEGWMVYAVIVATALESLADPPLRSIASVHVPPSAQGELQGALTSISSMTTIIGPLMFT 363
Query: 390 VIFYLF 395
IF F
Sbjct: 364 QIFAYF 369
>UniRef50_A3WCL4 Cluster: Permease; n=1; Erythrobacter sp. NAP1|Rep:
Permease - Erythrobacter sp. NAP1
Length = 416
Score = 127 bits (306), Expect = 7e-28
Identities = 96/412 (23%), Positives = 183/412 (44%), Gaps = 31/412 (7%)
Query: 36 SVFHALVVIFLEFFAWGLLT--MP-IISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLI 92
++F +++F++ GL+ +P ++ + D T + G ++ ++ F AP+I
Sbjct: 14 TLFFVALIVFIDMVGIGLIVPVLPGLLEEVTGETLDQTAQIGGWLLFAYAVMQFTFAPII 73
Query: 93 GALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADV 150
G LSD +GR+ LL T+F +M +W F +SG+ +++ + +ADV
Sbjct: 74 GGLSDRFGRRPVLLFTLFMLGVDYAIMAWAPTLFWLFVGRILSGIMGASWAAANSAIADV 133
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVA 208
ER + +G++ A AA VI P +G L +D+ + ++++
Sbjct: 134 AEPEERGKFFGIMGAAGAAGFVIGPGIGGLLGSIDVRLPFIAASLLAIGGAIAGYWLL-- 191
Query: 209 VPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
E+LP R G+ S +A+P L ++ V +F + S
Sbjct: 192 -KETLPSG-RRRGF----SITRANPLGTLIQMARHPVVFGFLTVIFFMQMAAQSHQSVWA 245
Query: 269 VYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWY 327
+ +LV G+ +Q+ + +A+ GV+ Q + G ++ +GA T+++G + + + +
Sbjct: 246 YHTELVFGWSTLQIGLSVALYGVMVAVTQGGLTGMIIARIGAARTVLIGFIISLPANLMF 305
Query: 328 GFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAM 387
F + M V+ +LG++ +PAI +S D QG +QG V + + +GP +
Sbjct: 306 AFAPAGYFMIIGIVIGSLGAMAFPAIQQMMSERIADDAQGELQGAVASTMSITSIIGPLI 365
Query: 388 FGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLVTAF 439
F F + L PG P++L AL AL + A+
Sbjct: 366 MTRAFGTF---------------ADSEGLYFPGAPYLLAALFGATALGIAAW 402
>UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=1;
Acidiphilium cryptum JF-5|Rep: Major facilitator
superfamily MFS_1 - Acidiphilium cryptum (strain JF-5)
Length = 405
Score = 126 bits (303), Expect = 2e-27
Identities = 115/413 (27%), Positives = 182/413 (44%), Gaps = 33/413 (7%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F LV+ + F + ++ L+AT H L G++ F +AP++G LS
Sbjct: 4 IFAVLVIDSIGFGLIAPILPDLVEKLSATPASHAALWVGVLSMTFAATQFFAAPVLGQLS 63
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEA 154
D +GR+ +LV++ + A L+ N W F I+G A S AY+AD+T
Sbjct: 64 DRFGRRRLILVSLAGSAANYLLLAFAPNLLWLFVGRLIAGATAGNVSAASAYIADITPPE 123
Query: 155 ERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
R++ +GL+ A F P +G +L +DL L F++ PES
Sbjct: 124 RRAQRFGLIGAAFGLGFTTGPVIGGFLGAIDLRLPFLVSAGLVAVNVVYGIFVL---PES 180
Query: 213 LP-EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV-Y 270
LP E+ RP +A P A+R + + L A + + G +FV Y
Sbjct: 181 LPPERRRP------FRLREATPLGAMRLLTTVPRLWRLAAAWSVRWFG-LGAIQAVFVLY 233
Query: 271 LKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
L G+G + IF A G+ S VQ ++ + LG + VG M +G
Sbjct: 234 ASLRFGWGPRENGIFFACTGIASTLVQFGLVRRAVTLLGERGAAFVGFACNAAAYMIFGV 293
Query: 330 GSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
++A L ALGSI PAI + +S + AD+QG + G ++ + GL + P
Sbjct: 294 APTASWLFAGVGLMALGSIANPAIRSMLSRAAPADQQGRMNGALSSIEGLTAIVAPLTGA 353
Query: 390 VIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVI-CALLVTAFLP 441
V+F F +G +P PG PFV+ A+++ A+LV + P
Sbjct: 354 VVFEAF----------SGVLPWR-----FPGAPFVMVAVMLAGAAMLVWSVKP 391
>UniRef50_A2SG94 Cluster: Tetracycline-efflux transporter; n=2;
Proteobacteria|Rep: Tetracycline-efflux transporter -
Methylibium petroleiphilum (strain PM1)
Length = 418
Score = 125 bits (301), Expect = 3e-27
Identities = 92/355 (25%), Positives = 165/355 (46%), Gaps = 17/355 (4%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATF---PDHTFLMNGLIMGIKGILSFLSAPLIGALSD 97
L+ + ++ + GL+ +P++ +L +F P T G++ I +F +P++GALSD
Sbjct: 16 LITVLIDMVSIGLI-IPVLPLLVGSFTGSPSDTAFWFGVVTFAFAIANFFGSPILGALSD 74
Query: 98 VWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVTTEAE 155
+GR+ LL+ ++T W A+ + G ++ AYVAD+T +
Sbjct: 75 RYGRRPVLLIGFCGLALNFFFTALSTALWMLVAVRLVGGAMQANAAVANAYVADITPPEQ 134
Query: 156 RSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVAVPESL 213
R+R +GL+ A F ++ P LG L +DL+ L + + +PESL
Sbjct: 135 RARRFGLLGAMFGLGFILGPVLGGLLGAIDLH---LPFYVAGSLALVNCLYGWLVLPESL 191
Query: 214 PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKL 273
P + R I W++A+PF+ALR + + V L + LS L + + +Y
Sbjct: 192 PAERR-----RAIDWKRANPFSALRDLAGLKGVGSLVAVLALSGLVQFTLHITWVLYTTY 246
Query: 274 VMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSR 332
G+G ++ + VG++S VQ ++LG L++ A+ + GL+ L + +G +
Sbjct: 247 KFGWGPLENGWSLFAVGLMSALVQGMLLGRLLRRFSAQRLAVTGLVSSSLAYVCWGLATE 306
Query: 333 TWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAM 387
WMM+ LG + + VS + QG G V+ + L + P +
Sbjct: 307 GWMMYVVIACNVLGFGVTACLQSIVSNAADPRTQGQTMGAVSSLNSLMAVVAPVI 361
>UniRef50_UPI000038DC0A Cluster: COG0477: Permeases of the major
facilitator superfamily; n=1; Nostoc punctiforme PCC
73102|Rep: COG0477: Permeases of the major facilitator
superfamily - Nostoc punctiforme PCC 73102
Length = 406
Score = 124 bits (300), Expect = 4e-27
Identities = 91/361 (25%), Positives = 164/361 (45%), Gaps = 6/361 (1%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+ +F++ +G++ +PI+ + F L++ I ++ FL APL G SD +GR
Sbjct: 15 LTVFIDLLGFGII-LPILPLYAEQFGAKPNEAT-LLVAIYSLMQFLFAPLWGRFSDRYGR 72
Query: 102 KFFLLVTVFFTC-APIPLMTINT-WWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRA 159
+ LL+T+F + A L N+ W F S++G+ A S AY+AD+TT A R+R
Sbjct: 73 RPILLLTLFGSVIAYAGLGFANSLWMLFLARSLAGIMAGNISTAQAYIADITTPANRARG 132
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRP 219
G++ A F ++ PA+G +L+ ++ F ++ LPE +
Sbjct: 133 MGIIGAAFGLGFILGPAIGGFLIGSDPDNANFHLPSLFSGGLSLFALLCALTLLPESLNS 192
Query: 220 TGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGV 279
+ + L ++ +L F A S + ++ K + +G
Sbjct: 193 ETKAKMQANRHRRRRLNLLQLSQRPQFCVLVGIYFFVTFAVAAMDSTLALWSKQQLNWGP 252
Query: 280 VQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWA 338
Q + A +G++S VQ ++GFL K G + +G+L L L+ GF ++
Sbjct: 253 QQTSYLFAFMGIVSTIVQGGLIGFLKKHFGEIKLLTLGILGLGLGLLLIGFSQSLILLLV 312
Query: 339 AGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHV 397
A L A G S++ P +++ +S + + QG + G+ + L +GP G+ F F
Sbjct: 313 ATTLVAWGISVSQPILNSLISQMTAPEEQGQILGIASSCSALARIVGPTWAGISFMKFGS 372
Query: 398 D 398
D
Sbjct: 373 D 373
>UniRef50_Q3BM88 Cluster: Drug:H+ antiporter-1 family protein; n=5;
Xanthomonas|Rep: Drug:H+ antiporter-1 family protein -
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length = 449
Score = 122 bits (295), Expect = 2e-26
Identities = 99/361 (27%), Positives = 169/361 (46%), Gaps = 13/361 (3%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGIL----SFLSAPLIGALSD 97
+ + ++ ++G++ +P++ L F +++ +G G L F+ +PL GALSD
Sbjct: 51 ITVLIDVLSFGVI-IPVLPDLVRHFTGGDYVVAAGWIGWFGFLFAAIQFVCSPLQGALSD 109
Query: 98 VWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAE 155
+GR+ +L++ LM I +++ ISGV + +FS AY+ADVT +
Sbjct: 110 RFGRRPVILLSCLGLGLDFILMAIAHSLPMLLLARVISGVCSASFSTANAYIADVTPPDK 169
Query: 156 RSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE 215
R+ A+G++ A F V P +G +L + G + +PESLP
Sbjct: 170 RAGAFGMLGAAFGIGFVAGPLIGGWLGSI-GLRWPFWFAAGLALLNVLYGWFVLPESLPA 228
Query: 216 KVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVM 275
+ R + W A+P AL+ + V L VFL+ L S ++
Sbjct: 229 ERRTAR----LDWSHANPLGALKLLRRYPQVFGLASVVFLANLAHYVYPSIFVLFAGYQY 284
Query: 276 GFGVVQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW 334
+G +V+ +A VGV SI V +L G L++ LG + +++GL ++ + YG
Sbjct: 285 HWGPREVSWVLAGVGVCSIIVNALLVGRLVRRLGERRALLLGLGCGVIGFIIYGLADSGT 344
Query: 335 MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
++AL +I P+ A ++ AD QG VQG +TG+ L GP +F +F
Sbjct: 345 AFLIGVPISALWAIAAPSAQALITREVGADAQGRVQGALTGLVSLAGIAGPLLFANVFAW 404
Query: 395 F 395
F
Sbjct: 405 F 405
>UniRef50_A3UGP9 Cluster: Probable transporter; n=1; Oceanicaulis
alexandrii HTCC2633|Rep: Probable transporter -
Oceanicaulis alexandrii HTCC2633
Length = 415
Score = 122 bits (294), Expect = 2e-26
Identities = 103/366 (28%), Positives = 173/366 (47%), Gaps = 29/366 (7%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWW--FFAMISI 132
G+ + ++ F+ +P+IG LSD +G + LL+++ LM + FF +
Sbjct: 61 GIATFVFALMQFVFSPIIGGLSDRFGCRPVLLLSLTALMVDFLLMGLAHALVVFFIARLL 120
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
SGVFA T S AY+AD++T ER+R +GL+ A A V+ PALG L +L +
Sbjct: 121 SGVFAATHSTANAYIADISTPEERARRFGLLGAAMGAGFVLGPALGGLLGELTPRAPFFA 180
Query: 193 XXXXXXXXXXFFIMVAVPESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCV 251
+ V VPESL PE RP SW++++ A L ++ + +L
Sbjct: 181 AAALAGVNALYGWFV-VPESLKPEHRRP------FSWKRSNSIATLLRLRRAEGLGVLVW 233
Query: 252 AVFLSYLPEAG-QYSCIFVYLKLV-MGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLG 308
FLS L AG Y ++ Y+ + G+ ++ I +A GVL + Q V+ FLM +G
Sbjct: 234 VYFLSQL--AGFVYPAVWSYIAIAKFGWTEGEIGISLAAYGVLFVICQAVVTPFLMPRIG 291
Query: 309 AKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGV 368
+ I + E + L+ T +++ + A + PA+ ++ + D QG
Sbjct: 292 ERRVIWIAFALEAVALIGLATAPTTLVLYLWLLPALFTGMEGPALQKVMTERTPPDAQGE 351
Query: 369 VQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGAL 428
+QG ++G+ + L P ++ +F+ F N G ++ PG PFV+ A+
Sbjct: 352 LQGGLSGLGAIVLILSPLIYTQLFFAF-------QNGVG-------GVVFPGAPFVMAAV 397
Query: 429 LVICAL 434
+ AL
Sbjct: 398 FNVIAL 403
>UniRef50_Q9RX43 Cluster: Tetracycline-efflux transporter; n=2;
Deinococcus|Rep: Tetracycline-efflux transporter -
Deinococcus radiodurans
Length = 407
Score = 122 bits (293), Expect = 3e-26
Identities = 86/323 (26%), Positives = 151/323 (46%), Gaps = 13/323 (4%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISI 132
G++ + F+ AP++G LSD +GR+ LL+++ L+ N WW I
Sbjct: 51 GVLTAAYAAMQFIFAPILGTLSDRFGRRPVLLLSLAGMVLDYLLLFFSPNLWWLLVGRLI 110
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
+GV + ++ AY+ADVT +R++ +G + AT+ ++ P LG +L + +G
Sbjct: 111 AGVTGASLTVANAYIADVTAPEDRAKNFGRLGATWGVGFILGPMLGGWLGE-HGLRAPFL 169
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
+ ++ +PESLP + R G + +PF LR + E +L
Sbjct: 170 FAAGLTALNFLYGLLVLPESLPPEKRGAAGGGTL-----NPFTPLRAL-TEYPLLRGLTL 223
Query: 253 VFLSYLPEAGQ--YSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGA 309
F+ L AGQ S +Y + V+ + +Q I A+ G+L+ GVQ ++ + G
Sbjct: 224 TFV-LLGLAGQVIVSTWVLYTEGVLRWSPLQNGIAFAVYGLLTAGVQAGLISPFIARFGE 282
Query: 310 KHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVV 369
+ TIM GL+ L+ + +++ + V+ ALG + PA+ +S QG V
Sbjct: 283 RRTIMTGLVASTLEFVVLSVARSAPVLYLSLVVGALGGLAQPAMQGLISRQVGEQEQGRV 342
Query: 370 QGMVTGVRGLCNGLGPAMFGVIF 392
G +T + L GP + +F
Sbjct: 343 MGAITSLNSLVGVFGPLLATSVF 365
>UniRef50_A0GXY1 Cluster: Major facilitator superfamily MFS_1; n=1;
Chloroflexus aggregans DSM 9485|Rep: Major facilitator
superfamily MFS_1 - Chloroflexus aggregans DSM 9485
Length = 402
Score = 121 bits (292), Expect = 4e-26
Identities = 96/356 (26%), Positives = 165/356 (46%), Gaps = 12/356 (3%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
+ ++ +GL+ MP++ + + + ++ GL+ + ++ L+APL+GALSD GR+
Sbjct: 14 VLVDMLGYGLI-MPLLPFMVQKWGGNATII-GLLGSLYALMQLLAAPLLGALSDRVGRRP 71
Query: 104 FLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYG 161
+L +F + + + + A I++ GV + + AY+ADVT+ ER+ +G
Sbjct: 72 VILGCLFGSALAYSWLALADSLPLLAAAIALGGVAGSSMPVAQAYIADVTSPTERTHGFG 131
Query: 162 LVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTG 221
L+ A F L+ A+G +L +G +L + + +PESLP R
Sbjct: 132 LLGAAFGLGLIGGAAIGGFLSQ-FGLALPPLVAATIALSNAIYASIVLPESLPPMRRHAS 190
Query: 222 WGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQ 281
P + F + +V L +AV L + AG S I +Y G+G Q
Sbjct: 191 SLPF-----RNLFGSALIALQASSVRPLLIAVMLLNITFAGLQSNIALYTLTRFGWGPDQ 245
Query: 282 VAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAG 340
AI VG+ + Q V++G L LG GL L + W+++
Sbjct: 246 NAILFVFVGLCAALTQGVLIGKLQSRLGDAWLASGGLGLMALAFAFVSGVYTDWLLFPLA 305
Query: 341 VLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
L A+G + PAI++ VS + +RQG+V G + + + +GPA FG +F F
Sbjct: 306 ALLAIGMGLAVPAITSLVSRQAGENRQGIVLGGMQALISVALLIGPASFGFLFDRF 361
>UniRef50_Q2G331 Cluster: Major facilitator superfamily MFS_1; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep: Major
facilitator superfamily MFS_1 - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 405
Score = 120 bits (290), Expect = 6e-26
Identities = 89/311 (28%), Positives = 140/311 (45%), Gaps = 14/311 (4%)
Query: 84 LSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL--MTINTWWFFAMISISGVFAVTFS 141
+ F+ AP+IG LSD +GR+ LL + L M + WW ++GV +FS
Sbjct: 57 MQFVFAPVIGNLSDRFGRRPVLLAAILMLGLDYLLQAMAPHFWWLIIGRLLAGVTGASFS 116
Query: 142 IVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXX 201
+AY+ADVT +R+ +G++ F V+ PA+G L+ L
Sbjct: 117 AAYAYIADVTPPEKRAANFGMMGLAFGFGFVVGPAMGG-LLGAISPRLPFYAASALALTN 175
Query: 202 XFFIMVAVPESL-PEKVRPTGWGPVISWEQADPFAALRKV-GAERTVLMLCVAVFLSYLP 259
F M + ESL PE RP W +A+ ++LR + G RTVL A+ L
Sbjct: 176 FVFGMFFLRESLAPENRRP------FDWRRANALSSLRALRGRSRTVLWFVAALGAWQLA 229
Query: 260 EAGQYSCIFVYLKL-VMGFGVVQVAIFIAIVGVLSIGVQVI-LGFLMKSLGAKHTIMVGL 317
Y ++ Y + GF V + +A+VG S VQ L F + LG + +++G+
Sbjct: 230 HV-VYPAVWPYFAIAAYGFSTRDVGLALAMVGFSSALVQGFGLRFALPRLGERRAVVLGV 288
Query: 318 LFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVR 377
+ Y TW ++ A + AL P I+A+ S A QG +QG V +
Sbjct: 289 AGLCASAVLYNLAQHTWQVYLAIAVGALQGFVQPPIAAFNSRAVDARSQGELQGAVQSIG 348
Query: 378 GLCNGLGPAMF 388
+ +GP ++
Sbjct: 349 SIAAIVGPPLY 359
>UniRef50_Q2MDB3 Cluster: Tetracycline efllux protein; n=6;
Proteobacteria|Rep: Tetracycline efllux protein -
Acinetobacter baumannii
Length = 363
Score = 120 bits (290), Expect = 6e-26
Identities = 80/330 (24%), Positives = 151/330 (45%), Gaps = 10/330 (3%)
Query: 67 PDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWF 126
P+ ++ G++ + + F+ +PL+GALSD WGR+ LL+++ + +T +
Sbjct: 5 PNSRYIYMGILASLYAAMQFIFSPLLGALSDRWGRRPVLLISLAGSAINYLFLTFSHSLI 64
Query: 127 FAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDL 184
++ I+G+ + ++ Y+ DV+ E R++ +GL++ATF A +I P LG +L +
Sbjct: 65 LLLVGRIIAGITSANMAVASTYIVDVSQENNRAKYFGLINATFGAGFIIGPVLGGFLSE- 123
Query: 185 YGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAER 244
YG L F +PES KV T +S +PF + + R
Sbjct: 124 YGLRLPFFAAAILTGLNLLFAYFVLPES--RKV--TLENKQLS--TLNPFKIFAGISSIR 177
Query: 245 TVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVIL-GFL 303
VL L F+ C ++ + V + + G+ + VQ+ +
Sbjct: 178 GVLPLVTTFFIFSAIGEVYGVCWALWGHDTFQWSGFWVGLSLGAFGLCQMLVQIFIPSHA 237
Query: 304 MKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRA 363
+ LG ++ ++ G+ L L F WM++A + ALGS+ P++ A S A
Sbjct: 238 SRLLGNRNAVLAGIACSCLALAVMAFAQNGWMIFAIMPIFALGSMGTPSLQALASQKVSA 297
Query: 364 DRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
++QG QG++ + + + P F +++
Sbjct: 298 EQQGQFQGVIASTVSMASMIAPMFFSTLYF 327
>UniRef50_Q8F6D6 Cluster: Tetracycline resistance protein, class A;
n=4; Bacteria|Rep: Tetracycline resistance protein,
class A - Leptospira interrogans
Length = 409
Score = 120 bits (289), Expect = 8e-26
Identities = 88/362 (24%), Positives = 162/362 (44%), Gaps = 16/362 (4%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLM----NGLIMGIKGILSFLSAPLIGALSD 97
V I ++ +G++ +P++ L T GL+M + F+ AP +G LSD
Sbjct: 18 VTILIDVIGFGII-IPVLPKLIQELTHGTLSQAAWYGGLLMFAYSFVQFVCAPFVGGLSD 76
Query: 98 VWGRKFFLLVTVF-FTCAPIPL-MTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAE 155
+GR+ LL ++F FT + L + +W F ++G+ +F+ +AY+AD++ +
Sbjct: 77 RYGRRPVLLASLFGFTLDYLFLAFAPSIFWLFVGRVLAGIMGASFTTGYAYIADISPPEK 136
Query: 156 RSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL-P 214
R++ +G++ A F +I P +G ++ YG F +PESL P
Sbjct: 137 RAQNFGILGAAFGFGFIIGPVIGG-ILGQYGSRAPFLAAAALTLINWLFGFFILPESLTP 195
Query: 215 EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLV 274
E R W++A+P +L + ++ L VA FL + Y
Sbjct: 196 ENRRK------FEWQKANPIGSLINLKRYPMIIGLVVAFFLMNVAAHSVQGTWNYYTMEK 249
Query: 275 MGFGVVQVAIFIAIVG-VLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRT 333
+ V + +VG V +I ++ ++ +LG +I +GL L + +++
Sbjct: 250 FQWNEAMVGYSLGVVGLVYAITQGGLIRIILPALGQNKSIYLGLALSGLGYALFALATQS 309
Query: 334 WMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
WMM+ + LG I P + +S ++ QG +QG +T + + LGP + +F
Sbjct: 310 WMMFVFLIPYCLGGIAMPPLQGIMSSQVPSNEQGELQGALTSLMSVTAILGPILMTGLFS 369
Query: 394 LF 395
F
Sbjct: 370 YF 371
>UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3;
Proteobacteria|Rep: Drug efflux protein TetA -
Agrobacterium tumefaciens
Length = 394
Score = 120 bits (288), Expect = 1e-25
Identities = 79/322 (24%), Positives = 156/322 (48%), Gaps = 10/322 (3%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISI 132
G+++G+ ++ F+ +P++GALSD +GR+ LL+++ T +M + W ++
Sbjct: 44 GVMLGVFAVMQFVFSPILGALSDRFGRRPVLLLSLAGTLLDYLVMAFSPLGWVLVVGRAM 103
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
+G+ + ++ AY+ D+T +R++ +G V A + +I P +G ++ +
Sbjct: 104 AGITSANMAVASAYITDITPAEQRAQRFGTVGAVMSLGFIIGPVIGG-VIGAWWLRAPFL 162
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
F + +PES R G G ++++ +P A L + + +L L
Sbjct: 163 VAALFNGLNLFVALFVLPES-----RKAGPGK-FAFKELNPLAPLVWLWNFKPLLPLVTV 216
Query: 253 VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKH 311
+ L A + +Y G+ V + + +++ GV Q L G L + G
Sbjct: 217 SVVFGLVAAIPGTIWVLYGAERFGWDSVHMGLSLSVFGVSGALAQAFLVGPLSRRFGDLG 276
Query: 312 TIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQG 371
T+M+G+ F+ML M F +++WM +A L ALG + PA+ + V+ D+QG +QG
Sbjct: 277 TLMIGVGFDMLAYMLMAFANQSWMGYAVAPLFALGGVAMPALQSLVTSRVSDDQQGQLQG 336
Query: 372 MVTGVRGLCNGLGPAMFGVIFY 393
++ + L +GP + +F+
Sbjct: 337 VLASLMSLAGIIGPVLTTAVFF 358
>UniRef50_A3VN57 Cluster: Permease; n=1; Parvularcula bermudensis
HTCC2503|Rep: Permease - Parvularcula bermudensis
HTCC2503
Length = 441
Score = 118 bits (283), Expect = 4e-25
Identities = 109/407 (26%), Positives = 176/407 (43%), Gaps = 43/407 (10%)
Query: 35 PSVFHALVVIF----LEFFAWGLL--TMP-IISVLNATFPDHTFLMNGLIMGIKGILSFL 87
P+ ALV IF L G++ MP +++ L + + G +M + FL
Sbjct: 4 PAPRRALVFIFITVLLSMIGVGIILPVMPALLTDLTGFAEGESARLYGYLMFAYAAMQFL 63
Query: 88 SAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMT-INTW-WFFAMISISGVFAVTFSIVFA 145
+P+IGALSD +GR+ +LV++FF LM + T+ W +SG A TFS A
Sbjct: 64 FSPVIGALSDQYGRRPVILVSLFFYGIDFLLMAFVPTFGWLVLGRLLSGATAATFSTAGA 123
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXF-- 203
++ADV+ +R++ +G++ A F +I P LG L YG SL
Sbjct: 124 FIADVSPPEKRAQNFGIIGAAFGLGFIIGPVLGG-LAAAYGPSLAILFPSDSGVASALTA 182
Query: 204 -------------------FIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAER 244
F + A PESLP + R W +A+P L V R
Sbjct: 183 FGPRYPFLLASVVIFANFIFGLTAFPESLPVERRRA-----FDWRRANPIGGLISVSRNR 237
Query: 245 TVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGF-L 303
TVL++ A FL + + Y G+ + +++ ++ VG+ + VQ L
Sbjct: 238 TVLVIMGAYFLMQVAHHSFPAVWAFYTTAKFGWSALSISLSLSYVGITAAVVQGYLTRKA 297
Query: 304 MKSLGAKHTIMVGLLFEMLQLMWYGFGSRT--WM-MWAAGVLAALGSITYPAISAYVSVN 360
+ +LG +++G + L + Y F + W+ +W + ALG P + A ++
Sbjct: 298 IPALGETRAVVIGSVAMALSTLGYAFFTPAGPWVYVWIT--VGALGGFMMPGMQAKMTKA 355
Query: 361 SRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLNEGHNKTG 407
+ D QG +QG + + + P M IF F D EG + G
Sbjct: 356 TAEDAQGELQGAIASLSSITMAFSPLMMTQIFAAF-TDRTEGQDFPG 401
>UniRef50_Q62C01 Cluster: Multidrug resistance protein; n=16;
Proteobacteria|Rep: Multidrug resistance protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 429
Score = 117 bits (281), Expect = 8e-25
Identities = 96/364 (26%), Positives = 168/364 (46%), Gaps = 11/364 (3%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATF--PDHTFLMNGLIMGIKGILSFLSAPLIGA 94
V+ L+ + ++ G+ T + +L A P H +M G ++ + F+ P++GA
Sbjct: 29 VWIILLTLAVDAVGLGVATPVLPDLLRAVGERPAHVPVMLGSLITCFYFMQFVFGPIVGA 88
Query: 95 LSDVWGRKFFLLVTVFFTCAPIPL-MTINTWW-FFAMISISGVFAVTFSIVFAYVADVTT 152
LSD WGR+ LL+ + + T ++ A ++G+ A + ++ AY+ADVT
Sbjct: 89 LSDAWGRRPILLIALGGGALSYAIGATARSYGGLLAAHMLAGIAASSAAVATAYLADVTP 148
Query: 153 EAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
A R+R + L S+ L+ PA G L L G + + ES
Sbjct: 149 PALRARRFALASSVLGLGLIAGPAFGGVLGAL-GPRVPFVAAGAIAALNFVSAACFLRES 207
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
LP + R +SW +A+ F +LR V +R L AV L L SC +
Sbjct: 208 LPARRRVP-----VSWARANLFGSLRLVREDRVFRDLLAAVCLGMLAYGIYLSCFVLANA 262
Query: 273 LVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGS 331
+G+G + + +A +G+ +++ ++L L+ LG T +VG +L Y
Sbjct: 263 ARLGWGPRENGLALAGLGLGITLTQTLLLPRLVARLGEHRTALVGFGAFVLAYGLYSRAD 322
Query: 332 RTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
++ AA + AL I+ P++ + +SV++ RQG QG + + GL + + P + G +
Sbjct: 323 SVALVAAALAVHALSLISDPSVRSLISVHAGPQRQGEYQGALVCLTGLASSIAPLVGGNL 382
Query: 392 FYLF 395
F F
Sbjct: 383 FAFF 386
>UniRef50_Q4ZVR8 Cluster: General substrate transporter:Major
facilitator superfamily; n=2; Pseudomonas syringae|Rep:
General substrate transporter:Major facilitator
superfamily - Pseudomonas syringae pv. syringae (strain
B728a)
Length = 411
Score = 117 bits (281), Expect = 8e-25
Identities = 97/411 (23%), Positives = 184/411 (44%), Gaps = 28/411 (6%)
Query: 31 GIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATF----PDHTFLMNGLIMGIKGILSF 86
G P + L+++ L+ GL +P++ L AT +H L G+ + + + F
Sbjct: 8 GDTRPPMRFILLILGLDVLGIGL-AIPVMPTLIATIWPSSTEHVSLALGVALTLYSAMQF 66
Query: 87 LSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMI--SISGVFAVTFSIVF 144
L APL+GALSD GR+ LL+ + C + +I +I+G+ A +
Sbjct: 67 LCAPLLGALSDCHGRRPILLLALAGMCLGNLMAGFAGSLTVLLIGRAIAGITAANIATAM 126
Query: 145 AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFF 204
AY+AD++ +R+ YG + A +LV P +G L YG L +
Sbjct: 127 AYIADISEGEQRTHFYGAAGSVIAIALVFGPVIGGGLAS-YGPHLPFLVAGGLAAINLLY 185
Query: 205 IMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQY 264
+ +PESL + R W + +PF +LR + + + + +A S+
Sbjct: 186 GYMRLPESLAAEHRRA-----FEWRRTNPFGSLRGLWSTQGLRPYLLAATCSWFAYGIFQ 240
Query: 265 SCIFVYLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQ 323
SC + ++ G+ +++V+ +A + + ++ +V++ L + + I+ G +L
Sbjct: 241 SCFVLANQMRYGWSMLEVSYALAALALGMAFAQRVLVRKLTPIMSNQRIIVTGYACCLLG 300
Query: 324 LMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGL 383
+Y + W+ A+G I PA+ + +S ++ A QG +QG +T + L G+
Sbjct: 301 YGFYTAAASVWLTVVGMCFHAVGLIAEPALRSELSRHASAGHQGELQGGLTSLLSLVGGV 360
Query: 384 GPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICAL 434
P + +IF G + +H L + G PF++ L+ + A+
Sbjct: 361 APVIGALIF-------------AGNVGSGQHVLWL-GAPFLVSLLMYVLAI 397
>UniRef50_A3U1K1 Cluster: Putative transport transmembrane protein;
n=1; Oceanicola batsensis HTCC2597|Rep: Putative
transport transmembrane protein - Oceanicola batsensis
HTCC2597
Length = 428
Score = 114 bits (275), Expect = 4e-24
Identities = 108/408 (26%), Positives = 184/408 (45%), Gaps = 31/408 (7%)
Query: 51 WGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF 110
W ++ + V +A D + ++ G + + FL PLIG+LSD +GR+ LL+ +
Sbjct: 32 WPVIPALLRDVGHAELADAS-VIGGWMFAAYALAQFLFGPLIGSLSDAYGRRSLLLLAIG 90
Query: 111 FTCAPIPLMTIN-TWWFFAMISI-SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFA 168
+ T+W + I +G+ + I AY+ D+T R+RA+G++ A F
Sbjct: 91 GLAVDYVFSALAPTFWLLILGRIIAGICGASHIIATAYLTDITPPEGRARAFGMIGAAFG 150
Query: 169 ASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE-KVRPTGWGPVIS 227
VI PALG L+ +G + F +PESLP K RP +S
Sbjct: 151 LGFVIGPALGG-LLGEFGPRVPFWAAAALAAANFAFGYAVLPESLPPGKRRP------LS 203
Query: 228 WEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQ-YSCIFVYLKL-VMGFGVVQVAIF 285
+A+PF LR +VL L + + L + AGQ Y ++ + + G+ +
Sbjct: 204 LRRANPFGVLRVFRGYPSVLPLTMVLMLYFF--AGQVYPTLWTFWGIAAFGWTEATIGAT 261
Query: 286 IAIVGVLSIGVQVIL-GFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAA 344
+A+ G++S + +L G L++ +G I+ GL+ L + +G ++ V A
Sbjct: 262 LALFGIMSALTEGLLSGPLVRRMGESRVIVAGLIVAALGAVGFGLAGSLAVVLILLVFVA 321
Query: 345 LGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLNEGHN 404
+ +P + + ++ + D QG +QG G+ L N + VIFY + +
Sbjct: 322 FEGLVHPCLVSLMTRDVPDDAQGELQG---GLASLTN--IATLAAVIFY------TQVFS 370
Query: 405 KTGRIPEERHALLVPGPPFVL-GALLVICALLVTAFLPEEDSNGRRAP 451
R PE A +PG PF++ G LL + L+ A P +G P
Sbjct: 371 WFVR-PEA--ASPMPGAPFLITGGLLALTLLIYLAVRPRGRGHGGLTP 415
>UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS)
permease; n=1; Flavobacterium psychrophilum
JIP02/86|Rep: Major facilitator superfamily (MFS)
permease - Flavobacterium psychrophilum (strain JIP02/86
/ ATCC 49511)
Length = 411
Score = 113 bits (273), Expect = 7e-24
Identities = 97/408 (23%), Positives = 184/408 (45%), Gaps = 28/408 (6%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIIS--VLNATFPDHTFLMN--GLIMGIKGILSFLSAPL 91
++ L+V+ ++ +GL+ P++ ++N D + G + I+ F+ AP+
Sbjct: 8 TLIFVLIVVVIDTAGFGLI-FPVLPQLLINLLHSDISTAAKYGGWLSFAYAIMQFVFAPV 66
Query: 92 IGALSDVWGRKFFLLVTVF-FTCAPIPL-MTINTWWFFAMISISGVFAVTFSIVFAYVAD 149
+G LSD +GR+ LL ++F F+ I L + W F +I+G+ ++S+ A VAD
Sbjct: 67 LGNLSDQYGRRPVLLSSLFGFSIDCIFLAFAPSILWLFVGRTIAGITGASYSVASACVAD 126
Query: 150 VTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAV 209
++T+ R++ +GL++A F +I P +G L +G F
Sbjct: 127 ISTDDNRTKNFGLINAGFGLGFIIGPIIGGTL-GQFGTHTPFIVAAILSFINFIFGYYFF 185
Query: 210 PESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV 269
PESL R W++A+PF +L+ + + L + + + S
Sbjct: 186 PESLKANNRRK-----FDWKRANPFGSLKHLQKFPLIKTLVLPMIFVSIANHSMESVWAF 240
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ + V +A +G+LSI VQ+ ++ L K L K ++G + M +
Sbjct: 241 FTIEKFKWSTSLVGYSLAFIGILSIIVQLWLVSILAKKLSDKRMAVLGFVLMMTGFFLFA 300
Query: 329 FGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
F W+++ A +L +G I A+ + +S + QG +QG + + GL + P +
Sbjct: 301 FTPWQWLLFTALLLFIVGGIQGTAVQSIMSSAMPDNEQGELQGALGSLMGLTTLIAPPLM 360
Query: 389 GVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLV 436
F F TG+ E + PG PF++ ++L + +L++
Sbjct: 361 TSSFSYF----------TGKQSE----IYFPGIPFLIASILTLISLIL 394
>UniRef50_P02981 Cluster: Tetracycline resistance protein, class C
(TetA(C)); n=117; root|Rep: Tetracycline resistance
protein, class C (TetA(C)) - Escherichia coli
Length = 396
Score = 112 bits (270), Expect = 2e-23
Identities = 93/364 (25%), Positives = 163/364 (44%), Gaps = 19/364 (5%)
Query: 39 HALVVIF--LEFFAWGL-LTMPIISVL--NATFPDHTFLMNGLIMGIKGILSFLSAPLIG 93
+AL+VI + A G+ L MP++ L + D G+++ + ++ FL AP++G
Sbjct: 5 NALIVILGTVTLDAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLG 64
Query: 94 ALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVT 151
ALSD +GR+ LL ++ +M W +A ++G+ T ++ AY+AD+T
Sbjct: 65 ALSDRFGRRPVLLASLLGATIDYAIMATTPVLWILYAGRIVAGITGATGAVAGAYIADIT 124
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVAV 209
+R+R +GL+SA F +V P G L + L+ L F+M
Sbjct: 125 DGEDRARHFGLMSACFGVGMVAGPVAGGLLGAISLHAPFLAAAVLNGLNLLLGCFLM--- 181
Query: 210 PESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV 269
ES + RP P+ ++ +P ++ R V L F+ L + +
Sbjct: 182 QESHKGERRPM---PLRAF---NPVSSFRWARGMTIVAALMTVFFIMQLVGQVPAALWVI 235
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ + + + + +A+ G+L Q + G K G K I+ G+ + L +
Sbjct: 236 FGEDRFRWSATMIGLSLAVFGILHALAQAFVTGPATKRFGEKQAIIAGMAADALGYVLLA 295
Query: 329 FGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
F +R WM + +L A G I PA+ A +S D QG +QG + + L + GP +
Sbjct: 296 FATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQGSLAALTSLTSITGPLIV 355
Query: 389 GVIF 392
I+
Sbjct: 356 TAIY 359
>UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -
Leptospira borgpetersenii serovar Hardjo-bovis (strain
JB197)
Length = 408
Score = 112 bits (269), Expect = 2e-23
Identities = 77/324 (23%), Positives = 143/324 (44%), Gaps = 9/324 (2%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-FTCAPIPL-MTINTWWFFAMISI 132
GL+M + F+SAP +G LSD +GR+ LL ++F FT + L + +W F +
Sbjct: 54 GLLMFAYSFVQFISAPFVGGLSDRYGRRPILLASLFGFTLDYLFLAFAPSIFWLFVGRVV 113
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
SG+ +F+ +AY+AD++ +R++ +G++ A F +I P +G L +G
Sbjct: 114 SGIMGASFTTGYAYIADISPPEKRAQNFGILGAAFGLGFIIGPVIGGSL-GQFGSRAPFL 172
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
F +PESL ++ R W++A+P +L + ++ L +A
Sbjct: 173 AAAALTLVNWLFGFFVLPESLTDENRRK-----FEWKKANPIDSLINLKRYPMIVGLIIA 227
Query: 253 VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVG-VLSIGVQVILGFLMKSLGAKH 311
FL Y + + + +VG V ++ ++ ++ LG
Sbjct: 228 FFLINTAAHAVQGTWNYYTMEKFQWNEAMIGYSLGVVGLVYAVTQGGLIRIILPVLGQNR 287
Query: 312 TIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQG 371
+I +GL L + +++WMM+ + LG I P + +S QG +QG
Sbjct: 288 SIYLGLALSALGYALFAIATQSWMMFVFLIPYCLGGIAMPPLQGIMSSQVPPREQGELQG 347
Query: 372 MVTGVRGLCNGLGPAMFGVIFYLF 395
+T + + + P + +F F
Sbjct: 348 ALTSLMSVTAIVEPILMTGLFSYF 371
>UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=2;
Sphingomonadaceae|Rep: Major facilitator superfamily
MFS_1 - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 412
Score = 111 bits (266), Expect = 5e-23
Identities = 95/374 (25%), Positives = 166/374 (44%), Gaps = 22/374 (5%)
Query: 41 LVVIFLEFFAWGLLTMPIIS--VLNATFPD--HTFLMNGLIMGIKGILSFLSAPLIGALS 96
+V IF++ +G++ MP++ V+ D H + I + + +FL++P++G LS
Sbjct: 11 VVTIFIDAVGFGII-MPVLPQLVMEVGQIDLPHAIEVGAWIGLVMAVATFLASPVLGNLS 69
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEA 154
D +GR+ LL+ + L+T+ W F ++SG+F +++ A +AD+T
Sbjct: 70 DRFGRRRILLLALGGLAVDYALLTVVETLPWLFVARALSGIFGGSYAAAQAAIADITPPE 129
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP 214
ER+R +G V A F V PA+G +L ++ + + + PE+LP
Sbjct: 130 ERARNFGFVGAAFGVGFVAGPAIGGFLGEMSPRAPFVAAAILATANMLYGYFI-FPETLP 188
Query: 215 -EKVRPTGW---GPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVY 270
E+ R W P+ +W+ AL + VL+L L Y P + CI
Sbjct: 189 KERRRAFDWRRANPLGAWKM---MRALPGMDGVAGVLVLWQIASLVY-PMTWSFYCI--- 241
Query: 271 LKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
+G+ + +A VGV +++G ++G + G + GLL + + Y F
Sbjct: 242 --AQLGWSPGMIGASLAAVGVMIALGQMFVVGPAVARFGERDAATFGLLVAVAVYIGYAF 299
Query: 330 GSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
+ T + + AL + P++ A +S + AD QG VQG+ GL P +
Sbjct: 300 TTSTLGAFLLLIPIALQAPVQPSLMAMMSRRATADTQGEVQGVSAMAMGLGQLAAPMLLT 359
Query: 390 VIFYLFHVDLNEGH 403
F D H
Sbjct: 360 GTMAYFTADAAPVH 373
>UniRef50_Q97L04 Cluster: Permease, probably tetracycline resistance
protein; n=30; Firmicutes|Rep: Permease, probably
tetracycline resistance protein - Clostridium
acetobutylicum
Length = 411
Score = 109 bits (262), Expect = 2e-22
Identities = 93/376 (24%), Positives = 176/376 (46%), Gaps = 18/376 (4%)
Query: 28 TMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATF---PDHTFLMNGLIMGIKGIL 84
T I + ++ L+ +FL + +++ P+I L + P + ++ L+ + I
Sbjct: 12 TKQTINKHALIFGLISVFLSGIGFTIIS-PVIPFLVQPYINNPGNQAIIVTLLTSVYAIC 70
Query: 85 SFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTIN--TWWFFAMISISGVFAVTFSI 142
F SAP +GALSD +GR+ LLV + + + I W FA I G+ T S
Sbjct: 71 MFFSAPGLGALSDKYGRRPVLLVCLLGSSIGYLIFGIGGALWVLFAGRIIDGITGGTIST 130
Query: 143 VFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXX 202
+FAY AD+ E ER++ +G VSA +I P LG L+ +G S+
Sbjct: 131 IFAYFADIIPENERTKYFGWVSAVVGVGTIIGPTLGG-LLAKFGYSVPLYFGAIITLLNV 189
Query: 203 FFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAG 262
+ +PESL + +R I++ + +PF L + + +++ L ++ FL ++P G
Sbjct: 190 VYGFFFMPESLDKNIRL----KEITFVRLNPFTQLANLLSIKSLKRLLISAFLLWIPN-G 244
Query: 263 QYSCIFVYLKL-VMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFE 320
+F + + + + +I+G I Q +I+ L+ L K+ ++G++ E
Sbjct: 245 SLQAVFSQFTIDTFSWKPAIIGLMFSIMGFQDIISQSLIMPKLLVKLSDKYIAILGMISE 304
Query: 321 MLQLMWYGFGSRTWM--MWAAGV-LAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGV 376
++ + + ++ AG+ + G SI P+ + +S + + QG +QG +
Sbjct: 305 VIGYSLIAASALFYFYPLFIAGMFIFGFGDSIFGPSFNGMLSKSVDSSEQGRIQGGSQSI 364
Query: 377 RGLCNGLGPAMFGVIF 392
+ L +GP + G I+
Sbjct: 365 QALARMIGPIIGGQIY 380
>UniRef50_Q5N0B7 Cluster: Multidrug-efflux transporter quinolene
resistance protein NorA; n=2; Synechococcus
elongatus|Rep: Multidrug-efflux transporter quinolene
resistance protein NorA - Synechococcus sp. (strain ATCC
27144 / PCC 6301 / SAUG 1402/1)(Anacystis nidulans)
Length = 403
Score = 109 bits (262), Expect = 2e-22
Identities = 95/364 (26%), Positives = 162/364 (44%), Gaps = 17/364 (4%)
Query: 38 FHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSD 97
F + +F++ LL +PI+ L F + FL+ G + + F+S P++G+LSD
Sbjct: 16 FSVALNVFMDALGVTLL-LPILPELLRPFGSNAFLL-GAFASVYTLAQFISTPVLGSLSD 73
Query: 98 VWGRKFFLLVTVFFTCAPIPLMTI-----NTWWFFAMISISGVFAVTFSIVFAYVADVTT 152
+GR+ L++T+ FT L+ + N FA ++G+ F+I AY+AD +
Sbjct: 74 RFGRRPPLILTLVFTGLAYVLLAVGSLVENLPLLFAARILAGLAGGVFAIAQAYIADRES 133
Query: 153 EA-ERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
+ +RS +G + A F + PALG L + L + V E
Sbjct: 134 DPLKRSTQFGWIGAAFGLGFLFGPALGGLLSGI-NLRLPIWFAAILAFINAALTVFTVVE 192
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
SLP + R ++ W+ +P L V + + F+ AG S +++
Sbjct: 193 SLPPERRR-----IVPWQDLNPLKQLWAVSRNPKLRRSLASAFIYNFAFAGFTSLFVLFV 247
Query: 272 KLVMGFGVVQVAIFIAIVGVLS-IGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYG-F 329
+ G+ +QVA + G S +G +I G L+ K ++GL + +W
Sbjct: 248 QNRFGWTPLQVAGVLIAGGFTSALGQGLIFGRLLPYFQEKGLALIGLGGMAVGYLWLAQV 307
Query: 330 GSRTWMMWAAGVLAAL-GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
+ ++ A +L AL G PA+S S A+ QG V G V G + L +GP +
Sbjct: 308 PTPGSQLYPAQILTALFGGFVIPALSGLFSRRVTAEEQGQVLGSVQGWQSLAQVIGPLIL 367
Query: 389 GVIF 392
GV++
Sbjct: 368 GVVY 371
>UniRef50_A0LD21 Cluster: Major facilitator superfamily MFS_1; n=1;
Magnetococcus sp. MC-1|Rep: Major facilitator
superfamily MFS_1 - Magnetococcus sp. (strain MC-1)
Length = 412
Score = 109 bits (261), Expect = 2e-22
Identities = 94/364 (25%), Positives = 169/364 (46%), Gaps = 23/364 (6%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMN-GLIMGIKGILSFLSAPLIGALSDVWGRK 102
+FL+ +GL+ +P++ + H M G++MGI ++ FL APL G LSD GR+
Sbjct: 14 VFLDLLGFGLV-LPLLPNYASDPMFHASTMEIGVLMGIYSLMQFLFAPLWGRLSDHIGRR 72
Query: 103 FFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRAY 160
L++ +F + + + ++S ++G + A +AD+T +R++A
Sbjct: 73 PVLIIGLFGSALSYLIYGLAESLMVLILSRALAGFMGANIAAAQAAMADLTPPEKRAQAM 132
Query: 161 GLVSATFAASLVISPALGAYLMDLYGES---LXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
G++ A F+ V+ PA+G YL YG S L F++ + E+
Sbjct: 133 GIIGAAFSLGFVLGPAMGGYLASTYGISAAPLAAALITGLNAVAALFLLSETRDLSTEQQ 192
Query: 218 RPTGWGPVISWEQADPFA--ALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVM 275
+P ++A P + ++ LM+C+ + L A + ++ +++M
Sbjct: 193 QPLS-------KRAHPLSLHPWKQARNYPGALMVCLFMGLFITLFAAFEMALPLWTQIIM 245
Query: 276 GFG-----VVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
G+ + + A VGV+ VQ I+ L+ +G T GL+ L LM G
Sbjct: 246 GWDSGSQTMAENGHLFAFVGVVMAIVQGGIVRRLVPKIGEVRTAYSGLICIALGLMLLGQ 305
Query: 330 GSR-TWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
S T ++ A G+ A + +PA S+ VS+N+ D+QG++ G+ + L LGP
Sbjct: 306 ASNYTTLLIALGLAATGAGLVHPAFSSLVSLNTDKDKQGLMMGLFQSMGALGRVLGPLWA 365
Query: 389 GVIF 392
G+ F
Sbjct: 366 GIAF 369
>UniRef50_A3VAE1 Cluster: Tetracycline resistance protein; n=3;
Rhodobacterales|Rep: Tetracycline resistance protein -
Rhodobacterales bacterium HTCC2654
Length = 406
Score = 107 bits (258), Expect = 5e-22
Identities = 87/364 (23%), Positives = 158/364 (43%), Gaps = 14/364 (3%)
Query: 36 SVFHALVVIFLEFFAWGLL--TMP-IISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLI 92
+++ L I ++ GL+ MP ++ + A + ++ G++M FL AP +
Sbjct: 6 ALWFILATILIDAIGVGLIFPLMPDLMDRVGAGGASNGAVLGGILMAAYAATQFLCAPAV 65
Query: 93 GALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADV 150
G LSD GRK LLV + +M + T W A ++GV T+ AY+AD+
Sbjct: 66 GGLSDAVGRKPVLLVALATLAVDYVIMALATSFWLLLAGRLLAGVAGATYITATAYLADI 125
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVP 210
+T +R+ +GL+ ATF V+ PALG L + + F + V +P
Sbjct: 126 STPEKRAANFGLIGATFGIGFVLGPALGGLLAGIDVTAPFWVAAALSAANVAFGLAV-LP 184
Query: 211 ESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV 269
ESL P K R +PF A+R + + +F+ +
Sbjct: 185 ESLAPAKRR------AFRASDLNPFGAIRDAFRMPALALPLACMFVFEFANMVYPTLWAF 238
Query: 270 YLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ + G+ + +A GV +++ ++L L+K + + LL + +G
Sbjct: 239 WGREAFGWSATMIGGTLAAYGVGVALTQGLVLPALLKRMSEHGVLTFALLTGTVAAFAFG 298
Query: 329 FGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
F + W++ +A L + P ++A ++ + DRQGV+QG++ + L P +
Sbjct: 299 FTTAPWLVAVILPIACLSDMAPPTLTAIMANATDEDRQGVLQGVIASLGSLAAIFAPLLM 358
Query: 389 GVIF 392
+F
Sbjct: 359 TPLF 362
>UniRef50_Q07282 Cluster: Tetracycline resistance protein, class E
(TetA(E)); n=85; root|Rep: Tetracycline resistance
protein, class E (TetA(E)) - Escherichia coli
Length = 405
Score = 106 bits (255), Expect = 1e-21
Identities = 84/362 (23%), Positives = 165/362 (45%), Gaps = 12/362 (3%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMN--GLIMGIKGILSFLSAPLIG 93
+V ALV+IFL+ G++ MP++ L F + G+++ + ++ + APL+G
Sbjct: 4 TVMMALVIIFLDAMGIGII-MPVLPALLREFVGKANVAENYGVLLALYAMMQVIFAPLLG 62
Query: 94 ALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVT 151
SD GR+ LL+++ LM + W + I+G+ T ++ + +ADVT
Sbjct: 63 RWSDRIGRRPVLLLSLLGATLDYALMATASVVWVLYLGRLIAGITGATGAVAASTIADVT 122
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
E R+ +G++ A F ++ P +G + L ++ + +
Sbjct: 123 PEESRTHWFGMMGACFGGGMIAGPVIGGFAGQLSVQAPFMFAAAINGLAFLVSLFILHET 182
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
+V I+ + +++R++ + + L+ V F+ L + ++
Sbjct: 183 HNANQVSDELKNETIN----ETTSSIREMISPLSGLL--VVFFIIQLIGQIPATLWVLFG 236
Query: 272 KLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFG 330
+ + V V + +A+ G+ Q + GF+ K LG + I VG+L + L
Sbjct: 237 EERFAWDGVMVGVSLAVFGLTHALFQGLAAGFIAKHLGERKAIAVGILADGCGLFLLAVI 296
Query: 331 SRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
+++WM+W +L A G IT PA+ +SV QG +QG++T + L +GP +F
Sbjct: 297 TQSWMVWPVLLLLACGGITLPALQGIISVRVGQVAQGQLQGVLTSLTHLTAVIGPLVFAF 356
Query: 391 IF 392
++
Sbjct: 357 LY 358
>UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=4;
Chloroflexaceae|Rep: Major facilitator superfamily MFS_1
- Roseiflexus sp. RS-1
Length = 428
Score = 106 bits (254), Expect = 1e-21
Identities = 84/336 (25%), Positives = 145/336 (43%), Gaps = 19/336 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTV---------FFTCAPIPLMTINTWW 125
G +M ++ FL P++GALSD +GR+ LL++V F + + + T
Sbjct: 52 GALMASFALMQFLFTPVLGALSDRYGRRPILLISVLGSGLSYVLFGFAEYLSFLGVETVL 111
Query: 126 FFAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
I +SG+ + S AY+AD TT ER++ G++ A F ++ PALG L
Sbjct: 112 AILFIGRMLSGITGASISTAQAYIADTTTPEERTKGMGMIGAAFGLGFMLGPALGGLLST 171
Query: 184 LYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAE 243
+ E+ F +PESLP + R V +P + L +
Sbjct: 172 ISLEA-PAFVAAGLAFANVIFGYFKLPESLPPERR-----MVTPMRGMNPVSRLSALLRR 225
Query: 244 RTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGF 302
++ L + +FL + +G S V+ + GFG + A+ +VG+L++ +Q ++
Sbjct: 226 SSIRPLLIGIFLLNMAFSGLQSNFAVFSDVRFGFGPLDNALIFTLVGLLAVVMQGFLIRR 285
Query: 303 LMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW-AAGVLAALGSITYPAISAYVSVNS 361
L+ + G + G+ + WM++ A G +A + PA++ +S
Sbjct: 286 LVLAFGETRLAIAGMTMMAGAFIAVALAPEAWMLFPAVGAIAIGDGMATPALTGLISRRV 345
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHV 397
A QG G G+ L P + G F L +V
Sbjct: 346 DAHEQGATLGGTQGLISLTRIAAPILAGTTFDLINV 381
>UniRef50_Q65F99 Cluster: Blt; n=2; Bacillus|Rep: Blt - Bacillus
licheniformis (strain DSM 13 / ATCC 14580)
Length = 398
Score = 102 bits (245), Expect = 2e-20
Identities = 79/323 (24%), Positives = 137/323 (42%), Gaps = 10/323 (3%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTV-FFTCAPIPLMTINTWWFFAMISIS 133
GL++ GI L +P+ G ++D +GR+ +++ + F + + + W + +
Sbjct: 43 GLLIAASGITQLLFSPVAGEMTDKYGRRKMIILGIGAFAVSQLLFALASQMWLLFVSRLL 102
Query: 134 GVFAVTFSI--VFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXX 191
G F + +FAY+AD+T+E +RS+ GL+SA + VI P G YL +G +
Sbjct: 103 GGAGAAFLVPAMFAYIADITSEKDRSKGMGLISAAMSLGFVIGPGAGGYLA-AFGLTFPF 161
Query: 192 XXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCV 251
++ +PE+L ++ V ++ +P A L +
Sbjct: 162 YVSAGLAGLATVLSLLVLPETLSQEKMLEKRRSV---QKREPLAKQMARALRSPYAFLFI 218
Query: 252 AVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAK 310
VF+ + +Y+ GF +A I ++ + VQ V LG L G K
Sbjct: 219 LVFILNFGIMNFEAVFSLYVDHKHGFTPGDIAFVITAASLIGVFVQAVALGMLTNRFGEK 278
Query: 311 HTIMVGLLFEMLQLMWYGFGSRTWMMWAAG-VLAALGSITYPAISAYVSVNSRADRQGVV 369
+ + L+ L W+++ A V L SI PAI+ +S D QG
Sbjct: 279 KLMNMTLIGSAGALAVCSIAGSYWLVFGATIVFFMLTSILRPAINTLIS-KMAGDEQGFA 337
Query: 370 QGMVTGVRGLCNGLGPAMFGVIF 392
GM L N +GP + G++F
Sbjct: 338 AGMNNAFMSLANIVGPTVAGLLF 360
>UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA -
Acinetobacter sp. LUH5605
Length = 395
Score = 102 bits (245), Expect = 2e-20
Identities = 83/360 (23%), Positives = 163/360 (45%), Gaps = 15/360 (4%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFP--DHTFLMNGLIMGIKGILSFLSAPLIGALSDV 98
L+ IFL+ GL+ MPI+ L + + + G ++ + ++ F+ AP++GALSD
Sbjct: 9 LITIFLDAVGIGLI-MPILPELLRSLAGAEAGGVHYGALLAVYALMQFIFAPILGALSDR 67
Query: 99 WGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAER 156
+GR+ L++++ A LM + W + +G+ ++ AYV+D+T ER
Sbjct: 68 FGRRPVLIISIAGATADYLLMAAAPSLLWLYIGRIFAGITGANMAVATAYVSDITPAHER 127
Query: 157 SRAYGLVSATFAASLVISPALGAYLMDLYGE-SLXXXXXXXXXXXXXFFIMVAVPESLPE 215
++ +GL+ A F + P +G L GE +L IM AV L E
Sbjct: 128 AKRFGLLGAVFGIGFIAGPVIGGVL----GEWNLHAPFFAAAFMNGINLIMTAV--LLKE 181
Query: 216 KVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVM 275
+ EQ+ + +L + + ++ + + + +Y +
Sbjct: 182 SKHSNKMTEKVQ-EQSILKKLSYLITQPNMAPLLGIFLIITLVSQVPATLWV-IYGQDRY 239
Query: 276 GFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW 334
G+ + + +A G+ SI + ++K G K+T++ G+ + + L+ W
Sbjct: 240 GWSIFIAGVSLASYGICHSIAQAFAIAPMVKRFGEKNTLLCGIACDAIGLLLLSIAVEEW 299
Query: 335 MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
+ +A L ALG + PA+ A +S +RQG +QG+++ L +GP + ++++
Sbjct: 300 VPFALLPLFALGGVAVPALQAMMSRGISDERQGELQGLLSSFNSLGAIIGPVLVTSLYFM 359
>UniRef50_Q8DMH7 Cluster: Multidrug-efflux transporter; n=2;
Cyanobacteria|Rep: Multidrug-efflux transporter -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 403
Score = 101 bits (243), Expect = 3e-20
Identities = 98/367 (26%), Positives = 157/367 (42%), Gaps = 21/367 (5%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F L+ I ++ L+ PI+ F F + L+ ++APL+GALS
Sbjct: 9 LFIVLLTIVIDRLGESLI-FPILPFFVERFNFDAFSLT-LLFSAFAAAQLIAAPLLGALS 66
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVTTEA 154
D WGR+ LL+ + T L + T W F I G+ S AY+AD + A
Sbjct: 67 DHWGRRPVLLICIAGTAVSYILFAVATAPWLLFVSRIIDGLTGGVVSTAQAYIADTSAPA 126
Query: 155 ERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
R++ +GL A F + PA+G L +DL +FI+ PES
Sbjct: 127 NRAKNFGLTGAAFGIGFIFGPAIGGSLAAIDLKLPIWFAAVLALVNVVLAYFIL---PES 183
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
LP R + S+ + AL +RT+ L +A F+ AG S ++LK
Sbjct: 184 LPAGQRSP--LTLKSFASQQQWLALFN---QRTLQALLMAFFIFNFAFAGFTSIFVLFLK 238
Query: 273 LVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYG--- 328
+ +G + I ++GV+S VQ ++ L+ G + + GLL L L+
Sbjct: 239 RQLSWGPAEAGIIFVMIGVVSTIVQAGLIRSLIPRFGEQCLSLGGLLLVALALLGIAAVP 298
Query: 329 -FGSRTW-MMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGP 385
GS + +++A + A G I P++ +S R QG + G ++ + GP
Sbjct: 299 TVGSLSVPLLYACVIGLAFGVGIMLPSLRGVISNRVRDQDQGKILGASQSLQSVAGIAGP 358
Query: 386 AMFGVIF 392
A G F
Sbjct: 359 AWAGWAF 365
>UniRef50_Q0LMR4 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: Major facilitator superfamily MFS_1 precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 391
Score = 101 bits (242), Expect = 4e-20
Identities = 86/318 (27%), Positives = 147/318 (46%), Gaps = 19/318 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISI 132
G+I+G ++ F+ AP++G LSD +GR+ L++++ T + L + W F
Sbjct: 42 GMIVGSYALMQFIFAPILGQLSDRYGRRPLLILSLIGTVCSLLLFGFANSLIWLFVGRMF 101
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
G SI AYV+D+TT+ +R+R G+V A + PA+GA L L
Sbjct: 102 DGATGGNISIAQAYVSDITTDKDRARGMGMVGAALGLGFIAGPAIGALLSKDGNYQLPIF 161
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
+V +PE PE+ P ++ AA+RK R +L + +
Sbjct: 162 VAAGIAVLSLILTIVVLPE--PERHAPQQGR---TFNPMKLLAAVRKPNVGR-LLSITLL 215
Query: 253 VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKH- 311
+ L+++ ++ +F +L FG Q +A VG++ V ++ G L++ L A+
Sbjct: 216 INLAFVAFETTFA-LFAARRL--EFGSHQTGYTLAGVGIV---VAIVQGGLIRRLAARFG 269
Query: 312 --TIMV-GLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQG 367
T++V G L L L GF W + A ++ A+G + P++S+ VS NS A +G
Sbjct: 270 EATLIVSGSLLLALSLAGLGFIQNVWHLVAICIVLAVGEGLLTPSLSSLVSRNSPASERG 329
Query: 368 VVQGMVTGVRGLCNGLGP 385
G+ + L P
Sbjct: 330 ENMGLYQSMSSLARIFAP 347
>UniRef50_A5FYH1 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Acidiphilium cryptum JF-5|Rep: Major
facilitator superfamily MFS_1 precursor - Acidiphilium
cryptum (strain JF-5)
Length = 413
Score = 101 bits (242), Expect = 4e-20
Identities = 87/342 (25%), Positives = 156/342 (45%), Gaps = 19/342 (5%)
Query: 84 LSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFS 141
+ F+++P++GALSD +GR+ +L++ +M + + W A +SG + +
Sbjct: 63 MQFIASPMLGALSDRFGRRPVILLSCLGQAVDFTVMALAPSVGWLLAGRILSGASSANIA 122
Query: 142 IVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXX 201
AY++DVT R+ A+G+ A V+ PALG L+ L
Sbjct: 123 AANAYISDVTPPERRAAAFGVSGVAAAIGFVLGPALGG-LLGAVSLRLPFWFAAGLSLAN 181
Query: 202 XFFIMVAVPESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
+ +VA+PESL P + R GW + + A F V A T+ L L +P
Sbjct: 182 FLYGLVALPESLAPRRRRRIGWRGLNPLD-ALRFYRRPGVAAPATIYALGTLA-LQAVP- 238
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLF 319
S + +Y++ G+ + +A GV ++ V++G +++ LG T+++GL+
Sbjct: 239 ----SVMVLYVQERFGWRPQLIGATLAAAGVGFAVVGGVVVGPMVRRLGEPRTLILGLIG 294
Query: 320 EMLQLMWYGFGSRTWMMW-AAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRG 378
+ +G + + W VL+A G + PA+ ++ QG +QG++ + G
Sbjct: 295 GAAGFVLFGLAPDSRIFWIGVPVLSAWG-LAMPAVQGIMAHRIGGREQGRLQGLLASLNG 353
Query: 379 LCNGLGPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPG 420
L +GP +F I+ G + T +P AL+V G
Sbjct: 354 LTALVGPLLFTTIY-----AATLGPDGTADVPRSGTALVVAG 390
>UniRef50_Q6MQK5 Cluster: Multidrug resistance protein; n=1;
Bdellovibrio bacteriovorus|Rep: Multidrug resistance
protein - Bdellovibrio bacteriovorus
Length = 405
Score = 100 bits (240), Expect = 7e-20
Identities = 91/358 (25%), Positives = 161/358 (44%), Gaps = 15/358 (4%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
+FL +G++ +PI+ +L+ F T L GL++ + ++ FL AP G LSD GR+
Sbjct: 17 VFLYLVGFGVV-IPILPILSRNF-GATALETGLLLSVYSLMQFLFAPFWGRLSDRMGRRP 74
Query: 104 FLLVT-VFFTCAPIPLMTINTW-WFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYG 161
LL V T + I + W F ++G F + S AY++D+T + ERS+
Sbjct: 75 ILLFCLVGETLSYIMFAWARSLEWLFVARILAGFFGASLSTASAYISDITPKHERSKGMA 134
Query: 162 LVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL--PEKVRP 219
L+ A F V+ PALG L ++G+ + + + L + ++
Sbjct: 135 LIGAAFGLGFVVGPALGGGLA-VWGQHINPAPHFDTSFASYWVAALCFANFLFGVKFLKE 193
Query: 220 TGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGV 279
+ S + F+ + + ++TV L LS L + + + +++ + V
Sbjct: 194 SLSEKSESAAKRKRFSIMWQYLNKKTVGPLMTVFLLSSLAMSSMEATLILFMGEKYQWDV 253
Query: 280 VQVAIFIAIVGVLSIGVQVILGFLMKSL----GAKHTIMVGLLFEMLQLMWYGFGSRTWM 335
QV+ A +GV+ I Q GFL++ L G + + +G+L L L
Sbjct: 254 KQVSFGFAYIGVIIIFTQ---GFLVRRLLPKWGERKVLRLGVLLLALGLTGIAIADSITG 310
Query: 336 MWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
M L +LG+ + P+ +S+ S A+ QG G+ + L LGPA+ G ++
Sbjct: 311 MAITMTLLSLGNGLANPSTLGSISLLSDANEQGAAMGVTQSMASLGRILGPALGGALY 368
>UniRef50_Q1IVW2 Cluster: Major facilitator superfamily MFS_1; n=1;
Deinococcus geothermalis DSM 11300|Rep: Major
facilitator superfamily MFS_1 - Deinococcus geothermalis
(strain DSM 11300)
Length = 411
Score = 100 bits (240), Expect = 7e-20
Identities = 99/379 (26%), Positives = 163/379 (43%), Gaps = 18/379 (4%)
Query: 27 MTMSGIGEPSVFHALVVIFLEFFAWGL---LTMPIISVLNATF-PD--HTFLMNGLIMGI 80
MT + EP L+ + + F + L L P++ + + P+ + G +
Sbjct: 1 MTTASSSEPPPRAPLLFLLVTAFLFSLGLSLVFPVLPYIVMQYVPEAGRQAAVLGWLGAS 60
Query: 81 KGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAV 138
+LSF +AP++GALSD +GR+ L++++ + + I + F SI G+ A
Sbjct: 61 YALLSFFAAPVLGALSDAYGRRPVLMLSLLGSAVGYVIFGIGGSLVMLFLGRSIDGLTAG 120
Query: 139 TFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXX 198
S +F Y+AD T E +R R +G V AT A +I PA+G L L S
Sbjct: 121 GMSALFGYLADTTPEEDRGRVFGQVGATVGAGFIIGPAVGGALSHL-SLSAPMFAAAAVC 179
Query: 199 XXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYL 258
+ +PESLP R + +P L A V L L L
Sbjct: 180 LLNLLWGAFVLPESLPVSRRSRHFDTA----HLNPLRQLSGALAFPAVRRLVTVSVLFIL 235
Query: 259 PEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGL 317
P + + + + + +G Q + +VGV I Q ++L +L+K+L + ++GL
Sbjct: 236 PFSIMQVAMALLARDTLSWGPAQTSTAFTLVGVCDIVAQGLLLPWLLKALRERGVALLGL 295
Query: 318 ---LFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMV 373
+ M+ L +++A+ + A G I A+ A VSV + D QG VQG
Sbjct: 296 GLGMLGMVGLALLPVLPSAALLYASVITFASGEGIFNAALGALVSVAAPPDAQGRVQGGT 355
Query: 374 TGVRGLCNGLGPAMFGVIF 392
+ L GP G ++
Sbjct: 356 QALSSLAQAAGPLAGGQLY 374
Score = 37.1 bits (82), Expect = 1.0
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Query: 253 VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHT 312
+ + Y+PEAG+ + + +L A +LS +LG L + G +
Sbjct: 39 IVMQYVPEAGRQAAVLGWLG--------------ASYALLSFFAAPVLGALSDAYGRRPV 84
Query: 313 IMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGM 372
+M+ LL + + +G G M++ + L + A+ Y++ + + +G V G
Sbjct: 85 LMLSLLGSAVGYVIFGIGGSLVMLFLGRSIDGLTAGGMSALFGYLADTTPEEDRGRVFGQ 144
Query: 373 VTGVRGLCNGLGPAMFGVIFYL 394
V G +GPA+ G + +L
Sbjct: 145 VGATVGAGFIIGPAVGGALSHL 166
>UniRef50_Q8VVJ1 Cluster: TetA protein; n=5; Actinomycetales|Rep:
TetA protein - Corynebacterium glutamicum
(Brevibacterium flavum)
Length = 407
Score = 99.1 bits (236), Expect = 2e-19
Identities = 85/368 (23%), Positives = 175/368 (47%), Gaps = 20/368 (5%)
Query: 40 ALVVIFLEFFAWGL-LTMPIISVL---NATFPDHTFLMNGLIMGIKGILSFLSAPLIGAL 95
A V+I A G+ L MPI+ L D L G+++ + ++ F+ AP++G L
Sbjct: 12 ATVLITASLDAAGMGLVMPILPALLHEAGVTADAVPLNVGVLIALYAVMQFIFAPVLGTL 71
Query: 96 SDVWGRKFFLLVTVF-FTCAPIPLMTINTWW-FFAMISISGVFAVTFSIVFAYVADVTTE 153
SD +GR+ LLV++ T + L T + F+ +++G+ T ++ +AD+T
Sbjct: 72 SDRFGRRRVLLVSLAGATVDYLVLATTSALSVFYIARAVAGITGATNAVTATVIADITPP 131
Query: 154 AERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL 213
+R++ +GL+SA + ++ PA+G L L + + E+
Sbjct: 132 HQRAKRFGLLSACYGGGMIAGPAMGG-LFGAISPHLPFLLAALLSASNLALTFILLRETR 190
Query: 214 PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKL 273
P+ P + +A+ + T L++ + + ++ +A + + ++ +
Sbjct: 191 PDS--PARSASLAQHRGRPGLSAVPGI----TFLLIAFGL-VQFIGQAPGATWV-LFTEH 242
Query: 274 VMGFGVVQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSR 332
+ + V+V I +++ G++ + VQ +L G +++ +G T+++G + + L L+ +
Sbjct: 243 RLDWSPVEVGISLSVFGIVQVLVQALLTGRIVEWIGEAKTVIIGCITDALGLVGLAIVTD 302
Query: 333 TWMMWAAGVLAAL--GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
+ M A +LAAL G I PA+ +S QG +QG++ + + + GP F
Sbjct: 303 AFSM--APILAALGIGGIGLPALQTLLSQRVDEQHQGRLQGVLASINSVTSIFGPVAFTT 360
Query: 391 IFYLFHVD 398
IF L +++
Sbjct: 361 IFALTYIN 368
>UniRef50_Q75TC8 Cluster: Multidrug-efflux transporter; n=3;
Geobacillus|Rep: Multidrug-efflux transporter -
Geobacillus kaustophilus
Length = 394
Score = 98.7 bits (235), Expect = 3e-19
Identities = 96/358 (26%), Positives = 150/358 (41%), Gaps = 19/358 (5%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+V+FL +G++ +P++ T T G +M + ++ FL AP+ G LSD +GR
Sbjct: 17 LVMFLVMAGFGII-IPVLPFYAETI-GATPTQLGWLMAVYSLMQFLFAPMWGNLSDRYGR 74
Query: 102 KFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVF-AVTFSIVFAYVADVTTEAERSR 158
K LLV +F L+ + T W FA I G A T AYVADVTTE +R +
Sbjct: 75 KPMLLVGIFGLALSFFLLAVATKLWMLFAARIIGGCLSAATMPAAMAYVADVTTEEDRGK 134
Query: 159 AYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
G++ A + P +G + + F+ V + ESLP + R
Sbjct: 135 GMGMIGAAVGLGFIFGPGIGG-VFSKASLTAPFWMAGSLALLTALFVFVFLHESLPREKR 193
Query: 219 PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFG 278
I ++ AAL+ A +L L L AG + + G
Sbjct: 194 MN-----IRTKRPSLAAALQGPVARLYLLQLITTFSL-----AGLEATFAYFAAERAGLS 243
Query: 279 VVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW 337
++ I+G+ VQ +LG L++S G I VGL + F W
Sbjct: 244 STELGYIFMIMGLAGAIVQGGLLGKLIRSFGEGAVIRVGLFLSAVGFFLILFVHSFWTAA 303
Query: 338 AAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
+ +G+ + P +SA ++ AD QG G+++ L GPA+ G +F L
Sbjct: 304 LYLTIFGIGNGVIRPCVSALLT-KYTADGQGSATGVLSSFDSLGRIGGPAIAGWLFTL 360
>UniRef50_A7H6K9 Cluster: Major facilitator superfamily MFS_1; n=2;
Anaeromyxobacter|Rep: Major facilitator superfamily
MFS_1 - Anaeromyxobacter sp. Fw109-5
Length = 386
Score = 97.9 bits (233), Expect = 5e-19
Identities = 95/350 (27%), Positives = 153/350 (43%), Gaps = 21/350 (6%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
V++F++ +G++ +P++ L A + GL+ + F+ AP+ G LSD GR
Sbjct: 12 VIVFIDLLGFGMV-IPVMP-LYAERLGASEAWTGLLSAGYSAMQFVFAPIWGRLSDRVGR 69
Query: 102 KFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFA----VTFSIVFAYVADVTTEAERS 157
+ LLV++ T L + FAM+ +S +FA +I A+VADVT R+
Sbjct: 70 RPVLLVSIAMTAVAFALYGLAGT--FAMLLVSRLFAGAATANIAIARAFVADVTPPEGRA 127
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
R G++ A F V+ PALG L Y SL +PE PE
Sbjct: 128 RGMGIIGAAFGLGFVLGPALGGVLSQ-YSLSLPGFAAAGLAAANGIAAWAILPE--PEH- 183
Query: 218 RPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF 277
S ++ FAA+R+ + + F++ L + + K G
Sbjct: 184 -------RYSVDRRRRFAAMREELGRPGIRRIIGIYFVTILAFSAMEATYAFLAKQRYGL 236
Query: 278 GVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF-GSRTWM 335
V+ A +GVL + VQ ++G L + G K ++ GL+ + L L F G+ +
Sbjct: 237 AESAVSYVFAYIGVLLVLVQGGLIGRLSRRFGEKRLLVTGLVLQALALAALPFAGTVPGL 296
Query: 336 MWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGP 385
+ A LA +T P +SA +S +RA+ QG G+ LGP
Sbjct: 297 LVATAPLAVGAGLTQPTLSALLSRFARAEDQGGTLGIGESAAAFGRILGP 346
>UniRef50_Q9KDN7 Cluster: Multidrug-efflux transporter; n=1;
Bacillus halodurans|Rep: Multidrug-efflux transporter -
Bacillus halodurans
Length = 399
Score = 94.7 bits (225), Expect = 5e-18
Identities = 90/359 (25%), Positives = 161/359 (44%), Gaps = 20/359 (5%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
+V +F+ GL+ +PI+ F + + GL++ I + FL AP G LSD G
Sbjct: 13 MVNMFVVMMGIGLV-IPILPYYIEAFGASSVEL-GLLIAIFSFMQFLLAPFWGRLSDKVG 70
Query: 101 RKFFLLVTVF-FTCAP-IPLMTINTWWFFAMISISGVF-AVTFSIVFAYVADVTTEAERS 157
RK + V +F F A I W F ++G F + AYV+D T+E +R
Sbjct: 71 RKPLIAVGMFGFAVAEFIFAFATQFWMLFVSRILAGAFGSAVMPAAMAYVSDRTSEEKRG 130
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
GL+ A+ A +V+ P +G +L + + + F ++ +PESLP +
Sbjct: 131 HGMGLLGASMALGIVVGPGIGGWLAE-FSLATPFLFAGFAASFAAIFSLLWLPESLPLEK 189
Query: 218 RPTGWGPVISWEQADPFAALRK-VGAERTVLMLCVAVFLSYLPEAGQYSCIF-VYLKLVM 275
R T PV + Q + A+R +G +L + LS+ + IF ++
Sbjct: 190 RKTEVEPVNQFVQM--WQAVRSPIG-----FLLFLVFGLSF--GLANFQTIFGIFALHRF 240
Query: 276 GFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW 334
+ +V + + G++ +I ++G L + G + ++ L + + W
Sbjct: 241 HYNPSEVGFIMVLTGIVGAIAQGSLVGRLTERYGEEKVVLGSLSLSGIGFLIMMLAFNYW 300
Query: 335 MMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ A L LG SI PA+ +++S D+QG++ G+ + L N +G + G++F
Sbjct: 301 TVIATTCLFFLGNSILRPAVQSFLS-KMAGDQQGMIMGLNNSILSLGNVVGALLAGLLF 358
Score = 54.0 bits (124), Expect = 8e-06
Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 2/147 (1%)
Query: 244 RTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFL 303
+ +LML V +F+ + G I Y G V++ + IAI + + G L
Sbjct: 7 KPLLMLMVNMFVVMMG-IGLVIPILPYYIEAFGASSVELGLLIAIFSFMQFLLAPFWGRL 65
Query: 304 MKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLA-ALGSITYPAISAYVSVNSR 362
+G K I VG+ + + F ++ WM++ + +LA A GS PA AYVS +
Sbjct: 66 SDKVGRKPLIAVGMFGFAVAEFIFAFATQFWMLFVSRILAGAFGSAVMPAAMAYVSDRTS 125
Query: 363 ADRQGVVQGMVTGVRGLCNGLGPAMFG 389
+++G G++ L +GP + G
Sbjct: 126 EEKRGHGMGLLGASMALGIVVGPGIGG 152
>UniRef50_Q5WGK5 Cluster: Major facilitator (MFS) superfamily
multidrug resistance protein; n=1; Bacillus clausii
KSM-K16|Rep: Major facilitator (MFS) superfamily
multidrug resistance protein - Bacillus clausii (strain
KSM-K16)
Length = 403
Score = 94.7 bits (225), Expect = 5e-18
Identities = 91/356 (25%), Positives = 156/356 (43%), Gaps = 16/356 (4%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
IF+ F GL+ + + +N T + GL++ + + FL AP G+ SD +GRK+
Sbjct: 19 IFIGFVGVGLVIPIMPTYMNVLGISGTIV--GLLVAVFSLTQFLVAPYAGSWSDRYGRKW 76
Query: 104 FLLVTVFFTCAPIPLMTINTWWFFAMIS-ISGVFAVTFSI--VFAYVADVTTEAERSRAY 160
++ + L + T IS + G +V F + V AYV D+TTE +R
Sbjct: 77 IIVAGLLLFAVSELLFGLATNAVLLFISRLLGGVSVAFIMPAVMAYVVDITTEEDRGMGM 136
Query: 161 GLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPT 220
G ++A + +I PA+G +L++ YG + M +PESL + P
Sbjct: 137 GWINAAISTGFIIGPAIGGFLVE-YGMRVPFFAAAGAAALSAVVSMSILPESLDKNKLP- 194
Query: 221 GWGPVISWEQAD-PFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF-VYLKLVMGFG 278
P ++ + A L K + RT + + L Q+ + +++ +
Sbjct: 195 --APEARMDRKESQLAQLAK--SYRTPYFTGLLIILITSLGLSQFETVLGLFVDHKYSYT 250
Query: 279 VVQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW 337
++A I I ++ +Q+ L G L+ +G K + LL + ++ F ++ WMM
Sbjct: 251 PNEIAWLIMIGAIVGAVMQLTLFGRLINWIGEKKLTVYCLLVMAVFMVATIFSAQYWMMV 310
Query: 338 AAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ L L PAIS Y S + QG+V G+ L N GP + G +F
Sbjct: 311 VSVTLVFLAVDFVRPAISTYFS-RIAGNEQGLVAGLNASYTSLGNIGGPILAGALF 365
>UniRef50_Q9A9E1 Cluster: Multidrug resistance protein, putative;
n=2; Caulobacter|Rep: Multidrug resistance protein,
putative - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 396
Score = 93.5 bits (222), Expect = 1e-17
Identities = 93/358 (25%), Positives = 146/358 (40%), Gaps = 11/358 (3%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
L+V+F+ +G++ +P++ A D + + F P G LSD G
Sbjct: 15 LLVVFINLVGFGVI-IPLLPFY-ARSMDAAPRQVTTMFAAYSLGQFFGEPFWGRLSDRIG 72
Query: 101 RKFFLLVTVFF-TCAPIPLMTINTWWFFAMISISGVFAV-TFSIVFAYVADVTTEAERSR 158
R+ L+VT+ T A + L W +I + G F S + Y+ADVT +R+
Sbjct: 73 RRPVLIVTIIANTLAYLALAFAPNIWVAMLIRLFGGFGSGNISTIQGYMADVTPPEKRAG 132
Query: 159 AYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
GL+ A F A VI P L +M +L + V + E
Sbjct: 133 RMGLLGAAFGAGFVIGPGL-VMVMQPGAGALGYQLPLFLAAAMAGTAALGVILFVKESRA 191
Query: 219 PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFG 278
P+ G QA AL + A + + + +S AG + +Y G+
Sbjct: 192 PSAPGA----PQAHRLEALSQAAAHPVLSRVLLVTLISTAAFAGMEAVFGLYADTRFGWT 247
Query: 279 VVQVAIFIAIVGVL-SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW 337
QVA A++GV+ SIG V+ G L + G + GL L+ F S+ +
Sbjct: 248 ASQVAACFALIGVIASIGQGVLTGRLARRFGEARVLTAGLSIIATSLLITPFISKPALAV 307
Query: 338 AAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
A A G S+ +P + A +S + DRQG + G+ L GP + G +F L
Sbjct: 308 VAVAFTAFGQSLVFPCVGALISRATPPDRQGQMLGLNMAAGSLARIGGPLLAGPLFGL 365
>UniRef50_A7CRQ2 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Opitutaceae bacterium TAV2|Rep: Major
facilitator superfamily MFS_1 precursor - Opitutaceae
bacterium TAV2
Length = 462
Score = 93.5 bits (222), Expect = 1e-17
Identities = 89/338 (26%), Positives = 147/338 (43%), Gaps = 19/338 (5%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTIN-TWWFFAMI 130
L G++ + +L F+ AP G LSD GR+ LL TV T L ++ ++W F +
Sbjct: 96 LFGGVVSSLFSLLQFVFAPFWGGLSDRRGRRGVLLFTVTGTAGSYLLWALSGSFWVFLVA 155
Query: 131 SI-SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGA----YLMDLY 185
+ G F S+ A VADVTT ER++A G+V A F LV P +GA + +
Sbjct: 156 RLLGGAFGGNLSVATAAVADVTTRKERAKAMGIVGAAFGLGLVTGPLVGAGAAQFNLLAR 215
Query: 186 GESLXXXXXXXXXXXXXFFIMVAVPESL------PEKVRPTGWGPVISWEQADPFAALRK 239
SL + ++V L E + P + +P A+
Sbjct: 216 HPSLAEWGVNPFTMPALIALGLSVVNLLWIGARFHETLTPDARDHSVEPRTRNPIRAILG 275
Query: 240 VG--AERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ 297
+ A R V ++ L+++ A + S +F+ + G+ Q + + +G+ SI Q
Sbjct: 276 LANPAVRGVNLVAFIYALAFV--AMETSLVFLGSER-FGYTARQNGMVMGFLGLCSIVTQ 332
Query: 298 -VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISA 355
I+ L+ + + GL+ L L+ GF ++ L A GS + P+ +
Sbjct: 333 GYIVRKLLNRVSETRILSGGLILTTLGLLCTGFAPYPVFLYLGAALLATGSGLVNPSTTG 392
Query: 356 YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
+S+ S D QG V G+ + L + P GVI+Y
Sbjct: 393 LISLYSSVDEQGRVLGIYRALGALARAITPLFAGVIYY 430
>UniRef50_Q0W1K3 Cluster: Putative permease; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative permease -
Uncultured methanogenic archaeon RC-I
Length = 410
Score = 93.1 bits (221), Expect = 1e-17
Identities = 85/367 (23%), Positives = 161/367 (43%), Gaps = 19/367 (5%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
LV +F+ +G++ +P+ L + L GL+M ++ FL AP G LSD G
Sbjct: 12 LVSMFIFTLGFGIV-VPVFGYLTKDM-GASALDLGLLMATMSLMQFLCAPTWGKLSDRIG 69
Query: 101 RKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVF-AVTFSIVFAYVADVTTEAERS 157
RK +L+ +F L +T W FA + G+ A + V AYV D+++ +R
Sbjct: 70 RKPVMLIGLFGFALSFILTGFSTQLWMLFAAQILGGLLSAGIWPAVLAYVTDISSPEDRG 129
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
+ G + A +++ PA+ + L +G ++ V +PESL +K
Sbjct: 130 KLMGFMGAASGLGIIVGPAISSILAG-WGLTVPFFAAAAIALATMLMGAVLLPESL-QKG 187
Query: 218 RPTGWGPVISWEQA--DPFAALRKVGAERTVLMLCVAVFLSY-------LPEAGQYSCIF 268
+ GP ++ P + + + C+ +Y L EA +
Sbjct: 188 KHISKGPKVALLDTLKTPLGMIFFIMLMVSFAGACLDGTATYFIMDKFSLTEAASSMPVL 247
Query: 269 VYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ + G V + I I+G++S+ Q+ +G L++ G K+T++ GL+ + +M
Sbjct: 248 NFTMTLTGPNV--MGIIFTIMGIMSVISQLAVGPLIQKYGEKNTMVFGLILVAVGMMCMP 305
Query: 329 FG-SRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAM 387
F ++ V+ ++ PA++ VS + DR G + G++ + LGP++
Sbjct: 306 FSMGLATLVITVSVMGVGMNLVNPAVNTLVSKQAPPDRIGAMMGLLGSFNSIGRVLGPSV 365
Query: 388 FGVIFYL 394
G + +
Sbjct: 366 GGAAYMI 372
Score = 61.3 bits (142), Expect = 5e-08
Identities = 40/147 (27%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
Query: 246 VLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMK 305
+++L V++F+ L G +F YL MG + + + +A + ++ G L
Sbjct: 8 LIVLLVSMFIFTLG-FGIVVPVFGYLTKDMGASALDLGLLMATMSLMQFLCAPTWGKLSD 66
Query: 306 SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSI-TYPAISAYVSVNSRAD 364
+G K +++GL L + GF ++ WM++AA +L L S +PA+ AYV+ S +
Sbjct: 67 RIGRKPVMLIGLFGFALSFILTGFSTQLWMLFAAQILGGLLSAGIWPAVLAYVTDISSPE 126
Query: 365 RQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+G + G + GL +GPA+ ++
Sbjct: 127 DRGKLMGFMGAASGLGIIVGPAISSIL 153
>UniRef50_Q6V4U1 Cluster: Putative multidrug efflux protein; n=1;
Enterococcus faecium|Rep: Putative multidrug efflux
protein - Enterococcus faecium (Streptococcus faecium)
Length = 395
Score = 92.3 bits (219), Expect = 3e-17
Identities = 88/364 (24%), Positives = 167/364 (45%), Gaps = 17/364 (4%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGAL 95
++F +V +F+ A+GL+ +PI+ F + +M GL++ GI+ +P+ G
Sbjct: 10 TLFLLMVCVFIATAAFGLI-IPILPDFMGKFNTNGQMM-GLLVATYGIIQLFLSPIAGRF 67
Query: 96 SDVWGRKFFLLV-TVFFTCAPIPL-MTINTWWFFAMISISGVFAVTFSI--VFAYVADVT 151
+D +GRK + + + T + + +++ W F ++G+ AV+ I A + D+T
Sbjct: 68 ADRYGRKRIIEIGLICLTLSQLVFAFSVHFWLLFLGRFLTGI-AVSLLIPGAMACIIDIT 126
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
TE ER++ ++A+ + VI P +G +L YG + +PE
Sbjct: 127 TEEERAKGLSFLNASISFGFVIGPGIGGFL-TTYGLYVPFYFATVLSFVSFLLSFFLLPE 185
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF-VY 270
+L +K T V LR + V +L VFL Y + IF ++
Sbjct: 186 TLEKKTEMTKADTVSPQPMVQQI--LRSIRVPYVVPLL--LVFL-YSVSLYIFEAIFGLF 240
Query: 271 LKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVG-LLFEMLQLMWYGF 329
+ G+ +A+ I I +S+ VQ++L + SL + +M G ++ + ++ F
Sbjct: 241 VAKQFGYTAKDIAMVITIAAFVSVMVQLLLTNKLVSLFGESKVMNGTMIAGGVSFLFLLF 300
Query: 330 GSRTW-MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
+R W ++ +L SI P I+ +S + + QG + GM L + +GP +
Sbjct: 301 TTRIWSILLLTCLLYTATSILRPVINTVLSKLAN-NEQGFIAGMNNAYVSLGSVVGPILG 359
Query: 389 GVIF 392
G++F
Sbjct: 360 GILF 363
>UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS family;
n=17; Cyanobacteria|Rep: Multidrug efflux transporter,
MFS family - Synechococcus sp. (strain WH8102)
Length = 432
Score = 91.9 bits (218), Expect = 3e-17
Identities = 96/357 (26%), Positives = 154/357 (43%), Gaps = 29/357 (8%)
Query: 56 MPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAP 115
+P++ L A F + GL+ G + F APLIGALSD +GRK + + V +
Sbjct: 43 LPLLPFLLADFSSSGSTV-GLLSGTYALSQFAVAPLIGALSDRFGRKPVISICVGGSVVG 101
Query: 116 IPLMTINT---W---W------------FFAMISISGVFAVTFSIVFAYVADVTTEAERS 157
+ L I W W F I G+ T + A +ADVTT R+
Sbjct: 102 MGLFAITLTVPWQQIWPGAAAAGVPLALLFTARIIDGISGGTAATATAVLADVTTPENRA 161
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
+A+GL+ F + P LG L ++ L + + +PE+ P +
Sbjct: 162 KAFGLIGVAFGLGFALGPGLGGVLGEM-NRILPAWGATGFAVVNLVMVSLLLPETHPLEA 220
Query: 218 RPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF 277
R P+ +P + L++V A V L +A F ++ G + + +YL+ +
Sbjct: 221 RK----PLPRKRALNPVSLLQRVFARPDVRRLALAFFGFFMAFNGFTTVLVLYLRNAFNW 276
Query: 278 GVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGL-LFEMLQLMWYGFGSRTWM 335
A+VGV+++ VQ ++G L+K G + GL L + LM T M
Sbjct: 277 TEGMAGAAFALVGVIAMVVQGGLIGPLVKRFGELRLTLAGLGLLSVGCLMVPLATEETSM 336
Query: 336 --MWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
+++A L ALG+ + P + A VS D QG G + G++ L LG + G
Sbjct: 337 PVIYSAVALLALGTGLVTPCLRALVSKRLTRDGQGAALGGLQGLQSLGTFLGASAAG 393
>UniRef50_Q0AX92 Cluster: Multidrug-efflux transporter; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Multidrug-efflux transporter - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 370
Score = 90.6 bits (215), Expect = 8e-17
Identities = 88/350 (25%), Positives = 153/350 (43%), Gaps = 19/350 (5%)
Query: 56 MPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-FTCA 114
MPI+ + F + GL+M + + F+ AP G+ SD GRK LLV +F FT
Sbjct: 1 MPILPYYAESMGASAFQL-GLLMTVYALCQFIFAPFWGSYSDRVGRKPVLLVGMFGFTLT 59
Query: 115 PIPLMTINTWW--FFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLV 172
N+ W F A I+ + T A + D ++ +R + G+V A+ ++
Sbjct: 60 FFIFALANSLWVLFVARIAGGALSCATVPTAMAVMGDTSSPEKRGASMGMVGASMGMGMI 119
Query: 173 ISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQAD 232
PA+G+ L + + F I+ V ESLP + R +S Q
Sbjct: 120 FGPAIGSGLAHI-SLAAPFVMAGSLSVVICFCILFLVKESLPVEDR-------VSEAQKI 171
Query: 233 PFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVL 292
A L K G + + L A+FL+ + EA ++ + +GFG + + + G+
Sbjct: 172 DRAPLLK-GLKSPLAFLFTAMFLASMAEATNMGTFALFAEGKLGFGPTSMGLIFSCAGLA 230
Query: 293 SIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQL-MWYGFGSRTWMMWAAGVLAALGSITY 350
S+ VQ ++G + G + T G++ ++ S ++ G+ +A +
Sbjct: 231 SVLVQGFVVGRAINKWGEEKTSGAGIILMASSFALFLQAKSLLELIIYMGIFSAGTGLIR 290
Query: 351 PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDLN 400
P+ISA S + QG G++ G L +GP++ G YL ++L+
Sbjct: 291 PSISAATSKRTTGS-QGTAMGVLQGYDSLGRVIGPSLGG---YLLDMNLS 336
>UniRef50_Q9KBZ9 Cluster: Multidrug-efflux transporter; n=2;
Bacillaceae|Rep: Multidrug-efflux transporter - Bacillus
halodurans
Length = 409
Score = 89.0 bits (211), Expect = 2e-16
Identities = 75/325 (23%), Positives = 146/325 (44%), Gaps = 15/325 (4%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-FTCAPIPLMTINT-WWFFAMISI 132
GL++ I + +P+ G +D +GR++ +++ + T + ++ WW +A +
Sbjct: 45 GLMIAIFAGAQLVMSPVAGKWTDQYGRRYMIILGLGGLTLSMFVFYFFDSIWWLYASRVV 104
Query: 133 SGV-FAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXX 191
GV A+ +FAYVAD+TT ER++ LVSA + V+ P +G +L D +G +
Sbjct: 105 GGVGAALLIPAIFAYVADITTIDERAKGNSLVSAAMSLGFVVGPGIGGFLAD-FGLKMPI 163
Query: 192 XXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKV--GAERTVLML 249
F ++ + ES E+ + ++ EQ ++++ ++ +
Sbjct: 164 LLSAILSLVAVLFSIMLLKESQTEEAKE------LTAEQVSESPLVKQLIQSVKKPYFIP 217
Query: 250 CVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLG 308
V + S + +++ G Q+AI + +G +S+ VQ+ ++ L++ LG
Sbjct: 218 LVITLVMSFGLMAYESILGLFVDNQFGATPGQIAILLTSIGTISVIVQLFVVERLVRWLG 277
Query: 309 AKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQG 367
+ + + L + F M +A + L SI P ++ +S + QG
Sbjct: 278 ERTVLSLFLGVASFGFLLSLFAPSYGMFFAVTMFIFLATSILRPVLTTLIS-KLAGNEQG 336
Query: 368 VVQGMVTGVRGLCNGLGPAMFGVIF 392
GM + N LGPA+ GV+F
Sbjct: 337 FAMGMNNAYMSIGNVLGPALAGVLF 361
Score = 42.3 bits (95), Expect = 0.027
Identities = 32/147 (21%), Positives = 67/147 (45%), Gaps = 2/147 (1%)
Query: 246 VLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMK 305
+++L + +F++ + YL+ + G G + IAI + + + G
Sbjct: 9 MILLMINMFIAIASFGIIIPILPAYLESI-GEGGTAAGLMIAIFAGAQLVMSPVAGKWTD 67
Query: 306 SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRAD 364
G ++ I++GL L + + F W ++A+ V+ +G ++ PAI AYV+ + D
Sbjct: 68 QYGRRYMIILGLGGLTLSMFVFYFFDSIWWLYASRVVGGVGAALLIPAIFAYVADITTID 127
Query: 365 RQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ +V+ L +GP + G +
Sbjct: 128 ERAKGNSLVSAAMSLGFVVGPGIGGFL 154
>UniRef50_A1B6I1 Cluster: Major facilitator superfamily MFS_1; n=1;
Paracoccus denitrificans PD1222|Rep: Major facilitator
superfamily MFS_1 - Paracoccus denitrificans (strain Pd
1222)
Length = 405
Score = 88.6 bits (210), Expect = 3e-16
Identities = 86/357 (24%), Positives = 152/357 (42%), Gaps = 14/357 (3%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
L V+ +E G++ +P++ + F T L GL++ + L+AP++G SD++G
Sbjct: 18 LAVVAVESAGLGMI-LPLLPFYASEF-GATPLTIGLLLASFSLCELLAAPILGKASDLFG 75
Query: 101 RKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSR 158
RK L+ + TCA L+ + N FA + G+ A SI AYV+D T +R +
Sbjct: 76 RKRLLVASQIGTCASFLLLALAPNLAVVFAARILGGLSAGNISIATAYVSDRTAPHKRRQ 135
Query: 159 AYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
A G VSA ++ PAL L + G ++ + +P + +
Sbjct: 136 AIGFVSAAMGVGTMVGPALAGVLAPM-GLAVPFGVAAVVSLASILATCLLLPAEGQQPIH 194
Query: 219 PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMG-- 276
P ++ Q AL +V + +L +F+++ Q++ + G
Sbjct: 195 KPAPAPFLA--QIGGLLALPQV---KHLLAALALLFMAFSLFGSQFALVLHARFQWQGRP 249
Query: 277 FGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWM 335
F ++ G ++I VQ V++ L K+L + M + M G
Sbjct: 250 FDPTEIGFVFVAAGAINILVQVVVMPLLGKALRERTLAMASFSLLAIGFMIIGLVGTVPA 309
Query: 336 MWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ A V+AA G ++ P + A +S+ A QG GM + L N + P G++
Sbjct: 310 LAAGIVMAATGIALARPTLVAALSLIVPATSQGAAMGMAQSMAALINIVAPIAGGLL 366
>UniRef50_Q9I4K4 Cluster: Probable major facilitator superfamily
(MFS) transporter; n=5; Pseudomonas aeruginosa|Rep:
Probable major facilitator superfamily (MFS) transporter
- Pseudomonas aeruginosa
Length = 422
Score = 85.8 bits (203), Expect = 2e-15
Identities = 83/357 (23%), Positives = 157/357 (43%), Gaps = 23/357 (6%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTF 140
+L +P++G+LSD +GR+ L++ + L+ + + W F +++G+ +
Sbjct: 71 LLQLFFSPVLGSLSDRFGRRPVLVLAMLGFALSYLLLALADSLWMLFLGRALAGLTGASV 130
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
+ A AD+ T +R+R +G + A A +++ PALG L+ ++G +L
Sbjct: 131 ATAMACAADLGTHGQRTRHFGWLYAGLALGMILGPALGG-LLAVHGTTLPLLLAAGLCLL 189
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
+ + E+LP R P R+ G R + +L + VFL L
Sbjct: 190 NALLAGLFLEETLPP-TRRRRLDPRRMNALRSISGLARQPGVGRLLAVLAL-VFLG-LQA 246
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVI-LGFLMKSLGAKHTIMVGLLF 319
FV K + + +A+ GVL++ Q + + + L + +GL
Sbjct: 247 VMVVWPFFVIEKF--HWSSAWIGYSLALYGVLAVLAQTLGVNLCKRRLDDARLLRLGLAL 304
Query: 320 EMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGL 379
+ L+ + ++ + A + ALGS+ PA+ +S DRQG +QG+++ + L
Sbjct: 305 QGCGLLLFALVDSSFWLVCALLPFALGSLATPAMQGLLSARVPVDRQGELQGVLSSLMSL 364
Query: 380 CNGLGPAMFGVIFYLFHVDLNEGHNKTGRIPEERHALLVPGPPFVLGALLVICALLV 436
+GP + +F+ G +P + G PF+ GALLV+ L++
Sbjct: 365 AAIVGPPLMSGLFHW-------GSGPLAPLP-------LAGAPFLAGALLVLAGLVL 407
>UniRef50_Q2SGJ5 Cluster: Permease of the major facilitator
superfamily; n=1; Hahella chejuensis KCTC 2396|Rep:
Permease of the major facilitator superfamily - Hahella
chejuensis (strain KCTC 2396)
Length = 414
Score = 85.8 bits (203), Expect = 2e-15
Identities = 83/328 (25%), Positives = 142/328 (43%), Gaps = 17/328 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-----TVFFTCAPIPLMTINTWWFFAM 129
G+ +G I F APL+GALSD GRK LL+ + + + L + W F A
Sbjct: 55 GVALGAFSIAMFFGAPLLGALSDGLGRKKTLLLCLSGLAMSYVFLALALAFKSLWLFMAG 114
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD--LYGE 187
I G F+ + + A + DVT E +R++ G + + V+ P +G YL D L
Sbjct: 115 RLIGGFFSGSLPVAQASIIDVTEEKQRAKYIGYIMFFVSLGYVVGPLIGGYLSDPALVPW 174
Query: 188 SLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVL 247
+++ + +K + A+ A+R + RT
Sbjct: 175 FNLQTPFIFVAALSVVNLLILLLVFQDQKRDAESRAMTLPNPIANLLDAVR-IKDIRTYA 233
Query: 248 MLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGFLMKS 306
+L + + + + + I +YL +GFG +V+ F++ VG L+ ++G MK
Sbjct: 234 LLLLLMLVGW---NTFFQFIGLYLTGGLGFGQQEVSSFVSWVGFGLAAAFLFLVGAAMKM 290
Query: 307 LGAKHTIMVGLLFEMLQLMWYG--FGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRA 363
L K MVGL ++ L G + + ++ VL A+G ++Y + A +S++ A
Sbjct: 291 L--KPLGMVGLALTLMALCIGGTLLSTHPYALYLLAVLGAVGFGLSYSGLMAQLSISVDA 348
Query: 364 DRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
RQG + GM + G FG +
Sbjct: 349 SRQGSMMGMAAAIAAFSAGFSGFAFGFV 376
>UniRef50_Q88YJ0 Cluster: Multidrug transport protein; n=5;
Lactobacillaceae|Rep: Multidrug transport protein -
Lactobacillus plantarum
Length = 398
Score = 85.0 bits (201), Expect = 4e-15
Identities = 80/360 (22%), Positives = 158/360 (43%), Gaps = 18/360 (5%)
Query: 41 LVVIFLEFFAW-GL-LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDV 98
L+++F EF G+ L +P++ + T G++ + + F+++P+IG +SD
Sbjct: 10 LILVFSEFLVCLGISLVIPVMPFIKNEL-HLTATDMGIMNALFALAQFVASPIIGRVSDK 68
Query: 99 WGRKFFLLV-TVFFTCAPIPLMTINTWWFFAMISISGVF--AVTFSIVFAYVADVTTEAE 155
GRK L V V + + + N W F + I G A+ A +D+TT+ +
Sbjct: 69 VGRKPVLTVGLVLYMVSEVLFALTNQLWVFNISRIVGGLSAAMVVPTAMALASDITTKRQ 128
Query: 156 RSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXXXXFFIMVAVPESL- 213
R++ G +SA F+ L++ P +G L + Y I++ +
Sbjct: 129 RAKVIGWLSAAFSGGLILGPGIGGVLAGISYKTPFWVAGALGLLSAIVLVILLPADRQID 188
Query: 214 PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKL 273
P++ T + F + +++L + +S G S +Y+
Sbjct: 189 PDREAITATTTTTNHPMTRAFWTV-------PIIILFTMILVSSFGLQGFESIYSIYVNE 241
Query: 274 VMGFGVVQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKHTIMVGLLFEMLQLMWYGFG-S 331
V F + +A+ + + G++S+ +QV L ++ G + I V L +W S
Sbjct: 242 VFHFSLSNIALVLTLNGLISLFLQVALFDTFVQRWGERRVIRVCFAAAALCTIWITQAHS 301
Query: 332 RTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ +M A V+ + + PAI+ ++ S A+ QG++ G+ + + N +GP M G++
Sbjct: 302 KVAVMVATLVIFSAFDLLRPAITTLLTKASEAN-QGLINGLNMSLTSVGNIVGPIMSGML 360
>UniRef50_A3IH26 Cluster: Multidrug resistance protein, putative;
n=1; Cyanothece sp. CCY 0110|Rep: Multidrug resistance
protein, putative - Cyanothece sp. CCY 0110
Length = 423
Score = 85.0 bits (201), Expect = 4e-15
Identities = 83/324 (25%), Positives = 138/324 (42%), Gaps = 24/324 (7%)
Query: 86 FLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIV 143
FL P++G+LSD GRK L+V++ T + + T W +A + G+ S+
Sbjct: 62 FLGTPILGSLSDRLGRKSILIVSLAGTVVANMVASFATVAWLLYAARVLDGLTGGNTSVA 121
Query: 144 FAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDL---YGES---LXXXXXXXX 197
A ++D+T ++R++A+G+ SATF V+ P L L G S +
Sbjct: 122 RAVISDITDASQRTKAFGIFSATFRLGFVVGPFLSYLAQQLPTFAGISSLGMSFVVSAAI 181
Query: 198 XXXXXFFIMVAVPESLPEKVRPTGWGPV---ISWEQADPFAALRKVGAERTVLMLCVAVF 254
+V +PE + +G +SW AL K+ T+ L
Sbjct: 182 ASIALLLTIVFLPEKRSRRDPHSGTQKEKFRLSWHD----FALGKIAKSATIPKLGQLFI 237
Query: 255 LSYLPEAGQYSCIFV-----YLKLVMGFGVVQVAIFIAIVGVLSIGVQVI-LGFLMKSLG 308
L++L +G IF + V+ ++AI AIVG+L QV L L K
Sbjct: 238 LTFL--SGSTFTIFTFAFQPFFLNVLNQNTKRLAIMFAIVGMLGFISQVFALEPLSKRFN 295
Query: 309 AKHTIMVGLLFEMLQ-LMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQG 367
+ I V L L ++ F + T + + A + S P I +S+N+ +QG
Sbjct: 296 LINIIAVTLAIRGLTFILMPAFPTFTAFVIILSIFALVNSFPMPLIDTVLSLNTSPQKQG 355
Query: 368 VVQGMVTGVRGLCNGLGPAMFGVI 391
V G+ + N +GP + G++
Sbjct: 356 EVLGINAAYLSIANAIGPMISGLL 379
>UniRef50_A7NVP3 Cluster: Chromosome chr18 scaffold_1, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr18 scaffold_1, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 456
Score = 84.6 bits (200), Expect = 5e-15
Identities = 88/389 (22%), Positives = 154/389 (39%), Gaps = 31/389 (7%)
Query: 39 HALVVIFLEFFAWGLLTMPIISVLNATF-PDH-----TFLMNGLIMGIKGILSFLSAPLI 92
H + +FL FA ++ I V A P + G I G+ + + PL+
Sbjct: 23 HLFMTVFLFNFATFMVIPAITDVTMAALCPGRDECSIAIYLTGFQQVIIGLGTLVMMPLV 82
Query: 93 GALSDVWGRKFFLLVTVFFTCAPIPLMTINTW--WFFAMISISGVFAVTFS-----IVFA 145
G LSD++GRK L + + T P+ ++ + +F+A + + ++ + A
Sbjct: 83 GNLSDMYGRKALLTIPMCLTIIPLAILAWSRSRNFFYAYFVLKTLTSMVCEGSVHCLTLA 142
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFI 205
YVAD E R+ A+G++S +++ V +L + F+
Sbjct: 143 YVADNIPEIRRASAFGVLSGVGSSAFVCGTLSARFLKTSSTFQVAASVAAVAAVYMKLFL 202
Query: 206 MV----------AVPESLPEKVRPTGWG----PVI-SWEQADPFAALRKVGAERTVLMLC 250
A+ E P + G PV S D +L + + T
Sbjct: 203 PDSVIKDGVLDRAILEQKPCVIHLDGESAQDSPVFKSMPSLDDMLSLLQTSS--TFTKAA 260
Query: 251 VAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGA 309
+ F S L + G ++ + YLK F Q A + I G+ +I V++ L ++G
Sbjct: 261 IVAFFSNLGDVGLHTSLMYYLKARFHFNKHQFADLMMISGIAGTISQLVLMPILAPTIGE 320
Query: 310 KHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVV 369
+ + +GLLF + Y W+ +AA + + L P I + S QG V
Sbjct: 321 EKLLAIGLLFSCSHMFLYSIAWSFWVPYAAAMFSILIVFAPPCIRSIASKQVGPSEQGKV 380
Query: 370 QGMVTGVRGLCNGLGPAMFGVIFYLFHVD 398
QG ++G+ + + P F + LF D
Sbjct: 381 QGCISGISSFAHLVSPLAFTPLTALFLSD 409
>UniRef50_A4ING5 Cluster: Multidrug-efflux transporter; n=1;
Geobacillus thermodenitrificans NG80-2|Rep:
Multidrug-efflux transporter - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 404
Score = 83.4 bits (197), Expect = 1e-14
Identities = 81/325 (24%), Positives = 142/325 (43%), Gaps = 17/325 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWW--FFAMIS 131
GL++ + + FL +P+ G ++D GRK ++ + F + + + FF+ +
Sbjct: 47 GLLVAVFSLTQFLFSPVAGRMADAVGRKKLIVSGMLLFAFSEWQFGYADHVFEMFFSRV- 105
Query: 132 ISGVFA-VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLX 190
I G+ A +T V AY AD+TT ER+ G ++A +I P +G Y+ + +G +
Sbjct: 106 IGGISAALTMPAVMAYAADITTNEERAAGIGYINAAITMGFMIGPGIGGYMAE-WGIRVP 164
Query: 191 XXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLC 250
+ +PES TG + + F L +V + L
Sbjct: 165 FNCAAAVGVMAAVITALFLPES--HSSASTG---TVQKDHVPFFVQLAQVHRQPYFFSLL 219
Query: 251 VAVFLSYLPEAGQYSCIF-VYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLG 308
+ LS+ + IF +++ GF ++A+ I I + VQ+ G+L+ G
Sbjct: 220 IIFALSF--GLANFETIFSLFVDHRFGFSPKEIALIITIGSIGGPLVQLTTFGWLLGHFG 277
Query: 309 AKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQG 367
+ + LL L ++ S M+ A VL L I PA+S +S +QG
Sbjct: 278 EQRVVSACLLLSALFIVLTLLASTWTMLLVATVLVFLAIDILRPAVSTQMSKIDET-QQG 336
Query: 368 VVQGMVTGVRGLCNGLGPAMFGVIF 392
+ G+ + L N +GPA+ GV+F
Sbjct: 337 YIAGLNSAFTSLGNIIGPAVAGVLF 361
Score = 34.7 bits (76), Expect = 5.4
Identities = 21/116 (18%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
Query: 275 MGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW 334
+G V + +A+ + + G + ++G K I+ G+L +G+ +
Sbjct: 39 LGISGGTVGLLVAVFSLTQFLFSPVAGRMADAVGRKKLIVSGMLLFAFSEWQFGYADHVF 98
Query: 335 MMWAAGVLAAL-GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
M+ + V+ + ++T PA+ AY + + + + G + + +GP + G
Sbjct: 99 EMFFSRVIGGISAALTMPAVMAYAADITTNEERAAGIGYINAAITMGFMIGPGIGG 154
>UniRef50_Q0W0M4 Cluster: Putative permease; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative permease -
Uncultured methanogenic archaeon RC-I
Length = 434
Score = 83.4 bits (197), Expect = 1e-14
Identities = 87/376 (23%), Positives = 165/376 (43%), Gaps = 28/376 (7%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
+F+ F +G++ +PII + F + GL++ L F P+ G +SD GRK
Sbjct: 15 VFIFTFGFGII-IPIIPYYTRSVNATAFDL-GLLLATFSFLQFFCGPIWGKISDHIGRKP 72
Query: 104 FLLVTVF-FTCAPIPL-MTINTWWFFAMISISGVFAV-TFSIVFAYVADVTTEAERSRAY 160
++ ++ FT A + ++ W F +SI G F+ F V A+VAD+T +ER++
Sbjct: 73 VIIFSLLGFTLAFAMVGLSSQLWMIFIAVSIGGFFSAGIFPAVLAFVADITQPSERAKLM 132
Query: 161 GLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP------ 214
GL+ A L++ P + L+ +YG S MV +PES+
Sbjct: 133 GLMGAVSGLGLILGP-FASSLLAVYGLSAPFFAAALISFITMIGCMVLIPESITYTQIVK 191
Query: 215 --EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA--------VFLSYLPEAGQY 264
+ V+P +I F AL+ + ML ++ F +L +
Sbjct: 192 IRDAVKPLSMLNMIIETFRHMFTALKTGLGVFLMAMLVISFAISGFEGTFTYFLMDKIGL 251
Query: 265 SCIFVYLKL----VMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLF 319
S + ++K+ + G + I A++G +S+ Q +I+ ++ G + I+ GLL
Sbjct: 252 SSVTSFVKVFDSGIHLTGPEAMGIVFAMMGAVSVICQGLIVAKAIEMFGEEKVIIFGLLI 311
Query: 320 EMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRG 378
+ ++ + + ++GS + +P ++ VS + QGV G+++
Sbjct: 312 ASVGMILLLTSTDLGTALIYICIISVGSGLVFPCLNTVVSRRTDERNQGVAMGILSSYGS 371
Query: 379 LCNGLGPAMFGVIFYL 394
LGP + G ++ +
Sbjct: 372 FGRVLGPIVGGYVYVI 387
Score = 39.5 bits (88), Expect = 0.19
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 2/141 (1%)
Query: 246 VLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMK 305
+L+L AVF+ + G I Y + + + +A L I G +
Sbjct: 8 LLVLTSAVFI-FTFGFGIIIPIIPYYTRSVNATAFDLGLLLATFSFLQFFCGPIWGKISD 66
Query: 306 SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSI-TYPAISAYVSVNSRAD 364
+G K I+ LL L G S+ WM++ A + S +PA+ A+V+ ++
Sbjct: 67 HIGRKPVIIFSLLGFTLAFAMVGLSSQLWMIFIAVSIGGFFSAGIFPAVLAFVADITQPS 126
Query: 365 RQGVVQGMVTGVRGLCNGLGP 385
+ + G++ V GL LGP
Sbjct: 127 ERAKLMGLMGAVSGLGLILGP 147
>UniRef50_A6G4P6 Cluster: Multidrug resistance protein, putative;
n=1; Plesiocystis pacifica SIR-1|Rep: Multidrug
resistance protein, putative - Plesiocystis pacifica
SIR-1
Length = 445
Score = 82.2 bits (194), Expect = 3e-14
Identities = 91/389 (23%), Positives = 160/389 (41%), Gaps = 39/389 (10%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
+FL+ +G++ +PI+ A D + M L+ F+ +P++G +SD +GR+
Sbjct: 30 LFLDLAGFGII-LPILPYY-AESMDASATMVALLSTTFSAAQFVMSPVLGRISDRYGRRP 87
Query: 104 FLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYG 161
+LV++ + ++ T W F ++G S AYVAD+ + +R++ G
Sbjct: 88 IMLVSIAGSALAALVLGFATALWLVFVARLVAGSSKANVSTAHAYVADLVPQEQRAKYMG 147
Query: 162 LVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES-LPEKVRPT 220
++ A V P +G ++ L+ + +PE+ P+ R T
Sbjct: 148 MMGAAMGLGFVFGPGIGG-MLALHSPHMPFFVSAGLSAVNFLMAAKWLPETHFPQAKRDT 206
Query: 221 GWGPVIS-------WEQADPFAALRKVGAERTVLM--LCVAVFLSYLPEAGQYSCIFVYL 271
G P S + P VG R M L F Y+ AG S + ++
Sbjct: 207 GHAPAASQISLRTRHKLLSPEGMREVVGKLRGTHMAWLIAIAFGFYISFAGMESTMALFT 266
Query: 272 KLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQL------ 324
+ + +G + +F+ +GV + Q +++G + +G T+ +GLL + L
Sbjct: 267 EHLFDWGAPETGVFMTFIGVNMVIFQGLLVGRAVDRMGEAKTLALGLLCLAIGLPLLGGV 326
Query: 325 ----MWYGFGSRT----------WMMWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVV 369
W G T M GVL + G+ ++ +SA VS S + QG
Sbjct: 327 DHISHWLGLDPTTAEGAASTSSLVFMALGGVLLSGGNGLSNATLSALVSRVSSPEEQGWN 386
Query: 370 QGMVTGVRGLCNGLGPAMFGVIFYLFHVD 398
G+ L GPA+ G +F HVD
Sbjct: 387 MGLKESASSLARVCGPALAGPLFQ--HVD 413
Score = 39.5 bits (88), Expect = 0.19
Identities = 33/168 (19%), Positives = 63/168 (37%), Gaps = 2/168 (1%)
Query: 224 PVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVA 283
P + A P + + R ++ + +FL L G I Y M VA
Sbjct: 2 PTLEEPSAAP-PPMSEADKRRALMTVAFTLFLD-LAGFGIILPILPYYAESMDASATMVA 59
Query: 284 IFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLA 343
+ + +LG + G + ++V + L + GF + W+++ A ++A
Sbjct: 60 LLSTTFSAAQFVMSPVLGRISDRYGRRPIMLVSIAGSALAALVLGFATALWLVFVARLVA 119
Query: 344 ALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
AYV+ +++ GM+ GL GP + G++
Sbjct: 120 GSSKANVSTAHAYVADLVPQEQRAKYMGMMGAAMGLGFVFGPGIGGML 167
>UniRef50_P39843 Cluster: Multidrug resistance protein 2; n=18;
Firmicutes|Rep: Multidrug resistance protein 2 -
Bacillus subtilis
Length = 400
Score = 82.2 bits (194), Expect = 3e-14
Identities = 89/360 (24%), Positives = 157/360 (43%), Gaps = 21/360 (5%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK- 102
IF+ F GL+ + S + + + G ++ I +++P G D +GRK
Sbjct: 19 IFVAFLGIGLIIPVMPSFMKIMHLSGSTM--GYLVAAFAISQLITSPFAGRWVDRFGRKK 76
Query: 103 FFLLVTVFFTCAPI--PLMTINTWWFFAMISISGVFAV-TFSIVFAYVADVTTEAERSRA 159
+L + F+ + + L T + ++F+ I + GV A V AYVAD+TT ERS+A
Sbjct: 77 MIILGLLIFSLSELIFGLGTHVSIFYFSRI-LGGVSAAFIMPAVTAYVADITTLKERSKA 135
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRP 219
G VSA + +I P G ++ +G + + + ESL + R
Sbjct: 136 MGYVSAAISTGFIIGPGAGGFIAG-FGIRMPFFFASAIALIAAVTSVFILKESLSIEER- 193
Query: 220 TGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGV 279
+ S + F K + + VF+ + + ++ GF
Sbjct: 194 ---HQLSSHTKESNFIKDLKRSIHPVYFIAFIIVFVMAFGLSAYETVFSLFSDHKFGFTP 250
Query: 280 VQVAIFIAIVGVLSIGVQVIL-GFLMKSLGAKHTI----MVGLLFEMLQLMWYGFGSRTW 334
+A I I ++++ +QV+L G L+ LG K I + G + + + GF T
Sbjct: 251 KDIAAIITISSIVAVVIQVLLFGKLVNKLGEKRMIQLCLITGAILAFVSTVMSGF--LTV 308
Query: 335 MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
++ + A + PA++A++S N ++QG V GM + L N GPA+ G++F L
Sbjct: 309 LLVTCFIFLAF-DLLRPALTAHLS-NMAGNQQGFVAGMNSTYTSLGNIFGPALGGILFDL 366
Score = 35.9 bits (79), Expect = 2.3
Identities = 28/156 (17%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Query: 238 RKVGAERTVLMLCVA-VFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGV 296
+ + ++T+ ++ ++ +F+++L G + +M + +A + +
Sbjct: 3 KSINEQKTIFIILLSNIFVAFLG-IGLIIPVMPSFMKIMHLSGSTMGYLVAAFAISQLIT 61
Query: 297 QVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAAL-GSITYPAISA 355
G + G K I++GLL L + +G G+ + + + +L + + PA++A
Sbjct: 62 SPFAGRWVDRFGRKKMIILGLLIFSLSELIFGLGTHVSIFYFSRILGGVSAAFIMPAVTA 121
Query: 356 YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
YV+ + + G V+ +GP G I
Sbjct: 122 YVADITTLKERSKAMGYVSAAISTGFIIGPGAGGFI 157
>UniRef50_Q192M5 Cluster: Major facilitator superfamily MFS_1; n=2;
Desulfitobacterium hafniense|Rep: Major facilitator
superfamily MFS_1 - Desulfitobacterium hafniense (strain
DCB-2)
Length = 392
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/359 (25%), Positives = 150/359 (41%), Gaps = 20/359 (5%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
+++ FL +G++ +PI+ L F + GL M I+ F AP G LSD G
Sbjct: 13 VIIQFLVMVGFGIV-IPILPFLIEELGGGAFSL-GLFMSAYSIMQFFFAPFWGRLSDRIG 70
Query: 101 RKFFLLVTVFFTCAPIPL--MTINTWWFFAMISISGVFA-VTFSIVFAYVADVTTEAERS 157
R+ LL+ + L M N A ++SGV + T AY+AD+T A+RS
Sbjct: 71 RRPVLLIGLSGYGITFFLYGMAGNLPLLIAFRALSGVVSSATLPTAMAYMADITEGADRS 130
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
++ G++ A +V PALG +L Y +L F +PE+L E
Sbjct: 131 KSMGMLGAAMGLGMVFGPALGGFL-GHYSFTLPFYFAGTLALLVLPFAWKLLPETLKE-- 187
Query: 218 RPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF 277
P + ++ P + L + F+ A S ++ +GF
Sbjct: 188 ------PNL---ESKPKVRFHPGVIRDPLFPLFIFNFVLSFTMAMFESTFTLFAAERVGF 238
Query: 278 GVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMM 336
G ++ I I+G+ + VQ +++G +++ G VG L + +W + ++
Sbjct: 239 GPQEMGIVFMIIGITGVIVQGMLIGKVVRRFGDAKPAKVGALLCAVAFLWLLWAPNAILL 298
Query: 337 WAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
V+ +G S P S+ VS NS QG G+ L GP + G I+ L
Sbjct: 299 VLGTVVFMIGNSFMVPTGSSLVSKNSHTG-QGASLGVFQSFGSLGRIAGPLVGGGIYGL 356
Score = 39.5 bits (88), Expect = 0.19
Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 4/150 (2%)
Query: 244 RTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFL 303
R +++L + FL + G I +L +G G + +F++ ++ G L
Sbjct: 7 RPMVILVIIQFL-VMVGFGIVIPILPFLIEELGGGAFSLGLFMSAYSIMQFFFAPFWGRL 65
Query: 304 MKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLA-ALGSITYPAISAYVS-VNS 361
+G + +++GL + YG ++ A L+ + S T P AY++ +
Sbjct: 66 SDRIGRRPVLLIGLSGYGITFFLYGMAGNLPLLIAFRALSGVVSSATLPTAMAYMADITE 125
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
ADR + GM+ GL GPA+ G +
Sbjct: 126 GADRSKSM-GMLGAAMGLGMVFGPALGGFL 154
>UniRef50_Q0W242 Cluster: Putative permease; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative permease -
Uncultured methanogenic archaeon RC-I
Length = 409
Score = 79.0 bits (186), Expect = 3e-13
Identities = 84/368 (22%), Positives = 157/368 (42%), Gaps = 20/368 (5%)
Query: 40 ALVVIFLEFFAWGL-LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDV 98
A+++ + F + G + MP++ + + F + GL+M ++ + P +G LSD
Sbjct: 12 AILIAGMFFLSLGFSVIMPVLPYYSQSMGASAFDL-GLLMASYSVMQLIFTPFLGELSDR 70
Query: 99 WGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAV-TFSIVFAYVADVTTEAE 155
GRK L+ +F + T W FA I G+ + + AY+AD+T+ E
Sbjct: 71 VGRKPVFLIGLFGYGVSFLIYGFATQLWMLFAARMIGGILSGGIYPASLAYIADITSHKE 130
Query: 156 RSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE 215
R R G++ A+ ++ PAL L ++G ++ + + ES
Sbjct: 131 RGRIMGMLGASSGLGMIFGPALSGGL-SIWGLTVPFFTIAAASFGFVVLGYLLLEESRSV 189
Query: 216 KVRPTGWGPV-ISWEQADPFAALRKVGAERTVLML-CVAVFLSYLPEAGQY------SCI 267
V G V I L + T+LM +VF YL G++ S +
Sbjct: 190 DVHRIRPGKVSILAPLRSRLWILFLLALLVTLLMSGFQSVFAYYL--MGRFGVMDTPSAM 247
Query: 268 FVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQ--L 324
V +M G +AI ++G+ + Q ++LG ++ +G +HT++ G+ L
Sbjct: 248 PVLGTTMMVTGPTIMAIMFTVMGITGVICQGILLGMTIEMIGERHTVITGMFIAAASFFL 307
Query: 325 MWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLG 384
+ + MM++ + G +T P +++ VS + + QG G++ + G
Sbjct: 308 ILAATELVSLMMFSCTLALGTGLVT-PCLNSLVSKRTDEEHQGAAMGVIGSYNSVGRIAG 366
Query: 385 PAMFGVIF 392
P + G+ F
Sbjct: 367 PPLGGLSF 374
>UniRef50_Q1D6T2 Cluster: Putative multidrug resistance protein;
n=1; Myxococcus xanthus DK 1622|Rep: Putative multidrug
resistance protein - Myxococcus xanthus (strain DK 1622)
Length = 400
Score = 78.6 bits (185), Expect = 3e-13
Identities = 80/358 (22%), Positives = 152/358 (42%), Gaps = 17/358 (4%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
V +FL+ +GL+ +P++ + T G+++ + +++P++G LSD GR
Sbjct: 11 VTVFLDLVGFGLI-IPLLPFYVESMGG-TATTAGVLLALFSFAQLVASPVLGRLSDRVGR 68
Query: 102 KFFLLVTVFFTCAPIPLMTINT---W--WFFAMISISGVFAVTFSIVFAYVADVTTEAER 156
+ +L+++ + L +T W W FA ++G A + A VADVT E+ R
Sbjct: 69 RPVILLSLLGNAISMALFAYSTHVQWLPWLFASRLLAGATAGNLAACQAAVADVTDESGR 128
Query: 157 SRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEK 216
+ GLV A +V+ P +G+ L+ ++G M+ V PE
Sbjct: 129 AAGMGLVGAGIGLGMVLGPVIGS-LLHVHGAWAPPLAGAVMAAAA----MLGVLFFFPET 183
Query: 217 VRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMG 276
RP E P L V A + + FL ++ + + + G
Sbjct: 184 HRPQA---ERHQEPGRPRVRLSDVLARPGLGAVLALTFLVFIGMTNLQVSLGLLAQARFG 240
Query: 277 FGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWM 335
+G ++ A++G+++ +Q ++G+L + ++VG L M
Sbjct: 241 WGEQEIGRLFALMGLVTFVLQAFVIGWLTSRVRDTTLVLVGAACMGAGLTCIAAAGHGAM 300
Query: 336 MWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ A VL G+ + P +++ S + + +G V G+V GL +GP G ++
Sbjct: 301 LVLAMVLVGSGTGLLQPLMASLASGFAGRELRGGVLGVVQSAGGLARVVGPVWSGFLY 358
>UniRef50_Q21E97 Cluster: Major facilitator superfamily MFS_1; n=1;
Saccharophagus degradans 2-40|Rep: Major facilitator
superfamily MFS_1 - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 413
Score = 77.4 bits (182), Expect = 8e-13
Identities = 73/359 (20%), Positives = 148/359 (41%), Gaps = 13/359 (3%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
++ L+ LL P+ + + + + ++ ++ + F +AP +G L D +GR+
Sbjct: 14 ILLLDIMGVSLL-WPVAAFIVQQYSNDAIMLT-VLTALYSAAQFFAAPFMGRLGDSYGRR 71
Query: 103 FFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRAY 160
L++++ +C + + + +IS + G A S+ AY+ADV+T R++ +
Sbjct: 72 PVLIISLLGSCIGYIMFGVGGALWVLLISRLLDGFTAGNQSVAGAYIADVSTPETRAKNF 131
Query: 161 GLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
L + +LV PALGA + L + +F + PESL + R
Sbjct: 132 TLFGMAWGVALVAGPALGAVFGEISLAAPAFLAATLCLLAALLSYFYL---PESLARENR 188
Query: 219 PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFG 278
+ I +PF + K+ ++ + + V + L G S +YL
Sbjct: 189 NS---TPIKLADINPFTTIIKLLSKPVLGSIFVVLILFNFVFNGFSSTESLYLVEKFSAT 245
Query: 279 VVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWA 338
+Q+ + G+ + +Q IL L+K G + +V L+ + +++
Sbjct: 246 PLQLGGLLTFAGLSLVAIQKILPPLIKRFGHQRVAVVSLIALAIMATITSITPAFNLLFG 305
Query: 339 AGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFH 396
L + + +P + A +S QG + G+ T + GP G+++ H
Sbjct: 306 VVSLRTMAAGFLFPILGALMSSMVTPKEQGALMGVNTALHSATYVFGPIWAGLVYDHLH 364
>UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera araneosa
HTCC2155|Rep: Ferrochelatase - Lentisphaera araneosa
HTCC2155
Length = 807
Score = 77.4 bits (182), Expect = 8e-13
Identities = 84/345 (24%), Positives = 144/345 (41%), Gaps = 26/345 (7%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS 131
L G ++ I L FL AP+ G +SD GR+ LL ++F + + +F +IS
Sbjct: 437 LFGGSLIFIYSFLQFLMAPVFGTISDRIGRRPILLFSIFGIALSYLIWFFSGSFFLLLIS 496
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALG---AYLMDL-- 184
ISG+ + A VAD T+E RSR ++ F ++ PA+G A+ +DL
Sbjct: 497 RLISGLMGSNITTATAAVADTTSEKTRSRGMAIIGIAFGLGFILGPAIGGLSAWAIDLST 556
Query: 185 ------YGE---SLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFA 235
YG S FF+ PE+LPE+ R G G + +P
Sbjct: 557 VSNWKDYGVNPFSAPAAIAFVLSMINFFFVYKKFPETLPEEKR--GKGEI--HRTINPI- 611
Query: 236 ALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVG-VLSI 294
L KV + V + F+ + + + +G+G + + +G VLS+
Sbjct: 612 KLFKVESYPGVSAVIFTNFIFLVAFGAAENMLTFLTDERLGYGPGKNGLLFVFIGFVLSM 671
Query: 295 GVQVILGFLMKSLGAKHTIMVGLLF---EMLQLMWYGFGSRTWMMWAAGVLAALGS-ITY 350
+ S+G GL+ + + G ++++ A+GS +
Sbjct: 672 VQGGYVRRKAASVGEGVVTKKGLIILIPGLTLVALAGLWQSAFVLYLGLFFMAVGSAMVI 731
Query: 351 PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
P ++A VS+ + A QG V G+ +GP + G++++ F
Sbjct: 732 PCLTALVSLYAPASDQGRVLGVYRSAGAFARTVGPILGGILYWKF 776
>UniRef50_A5GP24 Cluster: Permease of the major facilitator
superfamily; n=1; Synechococcus sp. WH 7803|Rep:
Permease of the major facilitator superfamily -
Synechococcus sp. (strain WH7803)
Length = 397
Score = 77.0 bits (181), Expect = 1e-12
Identities = 87/359 (24%), Positives = 160/359 (44%), Gaps = 21/359 (5%)
Query: 42 VVIFLEFFAWGLLTMPIIS--VLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
+V+ ++ ++GLL +P++ V T + + + G L FL APLIG LSD W
Sbjct: 11 LVVAVDAASFGLL-LPVVPFFVNELTGSFNAIAVTSVTATYSG-LQFLGAPLIGRLSDRW 68
Query: 100 GRKFFLLVTVFFTCAPIPLMTINTWWFFAMI--SISGVFAVTFSIVFAYVADVTTEA-ER 156
GR+ L VTV + + ++T ++ +++G + F+I A VAD + +R
Sbjct: 69 GRRSVLTVTVAISAIALIGQALSTSLLILLLFSALNGASSGVFAISQALVADTVEDRNQR 128
Query: 157 SRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEK 216
+ +G + A +I P +G L ++ +V + LP+
Sbjct: 129 TVGFGAIGAALGLGFIIGPGIGGAL-----GAIDPRFPFVVASAFCLLNVVLIRLYLPKT 183
Query: 217 VRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL-KLVM 275
R P S E+ L G R ++ + FL YL + +S IFV K
Sbjct: 184 TRSNQ--PEASTEKTKN--PLLTQGNHRLKKLISI-YFLFYLGFSA-FSGIFVLAAKERF 237
Query: 276 GFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW 334
+G ++ + VGV+++ VQ +L L+K++ ++GL + ++ S
Sbjct: 238 NWGPQPTSLVLVYVGVVAVVVQGALLPRLLKAIRPDKLSIIGLSLVAVAMLGVSVISEGR 297
Query: 335 MMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
++ L A G ++ P + + +S+ +QGV+ GM V L + +GP + G ++
Sbjct: 298 ELYVTQFLFAGGVGLSTPGLRSAMSLCVNESQQGVLGGMTQSVVSLTSLIGPLLAGQMY 356
>UniRef50_Q8GR72 Cluster: Multidrug efflux pump; n=7;
Lactobacillales|Rep: Multidrug efflux pump -
Enterococcus faecalis (Streptococcus faecalis)
Length = 393
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/366 (21%), Positives = 155/366 (42%), Gaps = 12/366 (3%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
++ A+ +FL F GL+ +P+I L M G+++ I I +++P+ G LS
Sbjct: 8 MYLAISNLFLVFLGVGLV-IPVIPQLKEEMHFSGTTM-GMMISIFAIAQLITSPIAGVLS 65
Query: 97 DVWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFA-VTFSIVFAYVADVTTE 153
D GRK + + VF + + F+ + G+ A + V A+VAD+TT
Sbjct: 66 DKIGRKKMIATGMLVFSISELLFGLAQAKSGFYISRGLGGIAAALLMPSVTAFVADMTTI 125
Query: 154 AERSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXXXXFFIMVAVPES 212
+ER +A GLVSA + +I P +G +++ G + F + +
Sbjct: 126 SERPKAMGLVSAAISGGFIIGPGVGGFIIGPGVGGFIAYLGIRAPFFAAAFLAFIGFILT 185
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
L P +++ +A + + L V + +S S +
Sbjct: 186 LTVLKEPE--KRILAAVEAKK-GSFMDILRNPMFTSLFVIILISSFGLQAFESIYSIMAT 242
Query: 273 LVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGS 331
+ GF ++AI I + G+L++ Q+ +++ +G I + + + F
Sbjct: 243 INFGFTTSEIAIVITVSGILALICQLFFFDAIVQKIGEMGLIQLTFFASAIFIAVIAFTK 302
Query: 332 RTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
++ + + L + PA++ Y+S ++ D+QG + G+ + N LGP G
Sbjct: 303 NNLVVVFSTFIVFLAFDLFRPAVTTYLSKHA-GDQQGTINGLNSTFTSFGNILGPMAAGA 361
Query: 391 IFYLFH 396
+F + H
Sbjct: 362 LFDINH 367
>UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG30345-PA - Tribolium castaneum
Length = 477
Score = 74.9 bits (176), Expect = 4e-12
Identities = 78/341 (22%), Positives = 137/341 (40%), Gaps = 23/341 (6%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTW------W 125
L+N + + + G +S ++ +IG SD +GRK L++ VF L+ + W
Sbjct: 76 LVNMVGLLVDGCISAVTCLVIGPWSDRFGRKPILIIPVFGFIVTYLLLALFAVLENLSPW 135
Query: 126 FFAMISI----SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL 181
+ + SI +G + +++ Y+ DVT E R G+ A + + + +Y+
Sbjct: 136 YILLCSIPILVTGGVSSYLTVLLCYITDVTNENNRGMRMGVFEALLSLGIFLGNVSSSYI 195
Query: 182 MDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKV- 240
S F M +PES+ P G + Q D L K
Sbjct: 196 FAATNYSTVFLLSSACCLLNLLFTMFFIPESITS---PESEGRLKGLFQFDNVTDLVKTT 252
Query: 241 -----GAERTVLMLCVAVF-LSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSI 294
+R V++ CV + L L G + +F++L+ + + Q +F A V +
Sbjct: 253 FKKRRNYDRCVVLSCVLMLTLFILVINGDGALVFLFLREKFHWSLEQYTLFSAAHNVTWV 312
Query: 295 -GVQVILGFLMKSLGAKHTIMV--GLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYP 351
G V + L K L T+M+ G + + + G +W ++AA ALG + P
Sbjct: 313 LGTAVGIYLLHKLLKIPETVMIVIGFISMFIGALVMGLAIYSWQVYAAAFSRALGGVLSP 372
Query: 352 AISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ + VS D G V ++ L G +F I+
Sbjct: 373 MVRSLVSKIVPNDEIGKVFALIVATESLIGMGGSPIFTAIY 413
>UniRef50_UPI00005842F8 Cluster: PREDICTED: hypothetical protein
isoform 1; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein isoform 1 -
Strongylocentrotus purpuratus
Length = 408
Score = 74.1 bits (174), Expect = 7e-12
Identities = 46/143 (32%), Positives = 80/143 (55%), Gaps = 6/143 (4%)
Query: 45 FLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFF 104
FL+ FA L+ +P+ S AT + GL+ I GIL +SAPL+G SD+ GR+
Sbjct: 16 FLDLFAVALI-IPVAS-RQATNLGASPASVGLVGTIYGILQLISAPLVGRWSDIGGRRST 73
Query: 105 LLVTVFFTCAPIPLMTINT---WWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYG 161
LL+ +FFT M ++T + A + + G+F + SI AY+A++T + +R++ +G
Sbjct: 74 LLLCLFFTSIGYIFMGLSTSIVHYLLARVPL-GIFKHSISITRAYLAEITPKDQRAKVFG 132
Query: 162 LVSATFAASLVISPALGAYLMDL 184
+ + +I P +G +L ++
Sbjct: 133 YFNGISSIGFIIGPLIGGHLAEM 155
>UniRef50_Q8F4V6 Cluster: Tetracycline resistance protein; n=4;
Leptospira|Rep: Tetracycline resistance protein -
Leptospira interrogans
Length = 445
Score = 73.7 bits (173), Expect = 1e-11
Identities = 66/333 (19%), Positives = 138/333 (41%), Gaps = 12/333 (3%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS 131
L G++ + IL F+ AP+ G +SD GRK L++T F + + + + F ++S
Sbjct: 78 LFGGIVASLYSILQFIFAPIWGRISDHVGRKPVLVLTSFGSFLGYVIWLFSGSFSFFVLS 137
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
I+G S+ A +AD+T E +R++ G++ A + P G + + L
Sbjct: 138 RVITGTMGGNISVASAAMADITNEKDRAKGMGMIGAGVGLGFIAGPPTGGLFAKINLDFL 197
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGW-------GPVISWEQADPFAALRKVGA 242
+ A +L + W ++ ++ P +
Sbjct: 198 KLVFPDLTFTVFPASALAATIIALINLLMILFWFRETFDQKDLLEKKKIHPILGV-FTSK 256
Query: 243 ERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILG 301
+ V++ + F+ +G I YL + + +++ +G++ + +Q +
Sbjct: 257 NKEVVLYSIFYFVFVFAFSGFEFSINFYLSQFLNYKPIEIGFTFVYIGMIIVLIQGGVFR 316
Query: 302 FLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVN 360
L + I +G ++ F S ++ ++ + A GS + +P++S VS+
Sbjct: 317 RLSGKVDETKLIRIGTFSLLVGFFILYFVSNSYQLFISLTFLASGSALLHPSLSTLVSLV 376
Query: 361 SRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
S + QG GM + L G+ P +F +I++
Sbjct: 377 SGKEEQGTNLGMFRSLASLGRGMAPFVFCLIYF 409
>UniRef50_A6BZ30 Cluster: Major facilitator superfamily MFS_1
transporter; n=1; Planctomyces maris DSM 8797|Rep: Major
facilitator superfamily MFS_1 transporter - Planctomyces
maris DSM 8797
Length = 432
Score = 73.3 bits (172), Expect = 1e-11
Identities = 87/389 (22%), Positives = 164/389 (42%), Gaps = 33/389 (8%)
Query: 29 MSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLS 88
MS + +F V +F++ +G++ +P++ F + GL+M + FL
Sbjct: 1 MSEGRKAGLFLIFVTVFIDLLGFGIV-LPLLPRYGEHFEAGGTTL-GLLMASFSAMQFLF 58
Query: 89 APLIGALSDVWGRKFFLLV-----TVFFTCAPIPLMTINTWWFFAMISIS---------G 134
AP+ G +SD GR+ L++ T F+ T F + ++S G
Sbjct: 59 APVWGRISDRVGRRPILILGLLGSTFFYGMFGFATSLGKTGMFLGIDALSWLFITRIGAG 118
Query: 135 VFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALG-AYLMDLYGESLXXXX 193
+ T AY+AD+T ER + L+ A F P +G A++ G +
Sbjct: 119 IAGATIPTAQAYIADITGPKERGKGMALIGAAFGIGFTFGPLIGAAFVSAETGATPSAAP 178
Query: 194 XXXXXXXXXFFIMVAV---PESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLC 250
++++ PESL +K + W F R + + ++
Sbjct: 179 GYVACVLSGMAALLSIFILPESLTKKTTDS-LARRHHWFDITSF---RHALTQPRIGLIL 234
Query: 251 VAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVG-VLSIGVQVILGFLMKSLGA 309
+A+FL+ A Q+ L +GF A +G +L++ ++ L+ LG
Sbjct: 235 LAIFLTTFAFA-QFESTLSLLTQELGFAARSNFFIFAYIGFILTLSQGFLVRRLIPRLGE 293
Query: 310 KHTIMVGLLFEMLQLMWYGF----GSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRAD 364
+ G++ ++ L+ G GS T M++A ++ +G S T P++ + +S+N+
Sbjct: 294 YRMGLFGIVLMVIGLLLIGVAGNSGSYT-MLYAVLPISVIGFSATTPSLQSLLSLNTSDA 352
Query: 365 RQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
QG + G+ + L LGP + G+I +
Sbjct: 353 EQGGILGVGQSISALARILGP-LAGIILF 380
>UniRef50_A4AC28 Cluster: Tetracycline-efflux transporter; n=1;
Congregibacter litoralis KT71|Rep: Tetracycline-efflux
transporter - Congregibacter litoralis KT71
Length = 389
Score = 73.3 bits (172), Expect = 1e-11
Identities = 80/354 (22%), Positives = 151/354 (42%), Gaps = 13/354 (3%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+V+ LE G++ +PI+ L+ F + +I+ + + ++ P G LSD GR
Sbjct: 3 IVLVLESSTLGIV-IPILPFLSPRLGASDFDI-AMIIASYAVCAGVAGPWWGKLSDHIGR 60
Query: 102 KFFLLV-TVFFTCAPIPLMTINTW-WFFAMISISGVFAVTFSIVFAYVADVTTEAERSRA 159
K L++ T A + L + + F + +G+ A F + A +AD+T A+R+R
Sbjct: 61 KPVLMICTTGAALAYVLLASAQSLTMIFVARAFAGLMAGNFGVASAMMADITPPADRARG 120
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRP 219
G++ A+F LV+ P LG L G ++A LPE
Sbjct: 121 MGMIGASFGLGLVLGPVLGGLLS---GPEGSFVVPCLTAAVMSVLAVIAAWFFLPESHHR 177
Query: 220 TGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGV 279
P + + LRK + +LML + + A ++VY ++ +
Sbjct: 178 DKSQPQTQERKLSLWTVLRK--TQSRLLMLQYIWHTASVSAATYLFPLWVY--ALLNWSA 233
Query: 280 VQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWA 338
+V I + G L Q +++G L+K LG + V + + L++ F M
Sbjct: 234 REVGIVFGVQGALMALTQGLLMGPLVKLLGELRLLRVCVSGFFVGLLFAVFAQGAVSMVG 293
Query: 339 AGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ ++A G ++ P ++++ S + + +G + G + LGP + G +
Sbjct: 294 SVLVALTGATLCMPVLNSFASQRAVPELRGRMMGATSAAAAWGRVLGPLLAGAL 347
>UniRef50_A3I4T4 Cluster: Blt; n=1; Bacillus sp. B14905|Rep: Blt -
Bacillus sp. B14905
Length = 384
Score = 73.3 bits (172), Expect = 1e-11
Identities = 70/325 (21%), Positives = 137/325 (42%), Gaps = 19/325 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFT-CAPIPL-MTINTWWFFAMISI 132
G+++ + F+ +P+ G LSD++GRK ++ + T A I ++ + W F +
Sbjct: 33 GMLIATFALAQFVFSPIAGNLSDLYGRKNLIIFGLILTGLAQIGFGLSTDVWMLFLARFL 92
Query: 133 SGV-FAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGESL 189
G+ A + A+VADVTT ER + ++ A + +I P +G +L + L+
Sbjct: 93 GGLGSAFVAPPIMAFVADVTTYEERGKGMSMLGAAMSFGFMIGPGIGGFLAKVSLHFPFF 152
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLML 249
+F++ P + P + + + A R V V+++
Sbjct: 153 MAGAAAILASILSYFLL---PSTKPNTAQNRQKQDNLVKQMA------RSVHMPYFVMLI 203
Query: 250 CVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLG 308
+ VF + +FV K + +A + + G + VQ+ I+ L K G
Sbjct: 204 IMMVFSFGIANFQTTLSLFVTEK--FNYSPGDIATILVVGGAFGVIVQMFIITPLFKRFG 261
Query: 309 AKHTIMVGLLFEMLQLMWYGFGSR-TWMMWAAGVLAALGSITYPAISAYVSVNSRADRQG 367
++V L + + F S ++ A + + ++ PA++ +S + + QG
Sbjct: 262 EMKVVLVNLFIASIAIFLILFVSGFALILVVATIFSTATTLIRPAVNTLISKLAETE-QG 320
Query: 368 VVQGMVTGVRGLCNGLGPAMFGVIF 392
G+ L N +GPA+ G +F
Sbjct: 321 FAAGLNNAYMSLGNMIGPALAGFLF 345
Score = 43.6 bits (98), Expect = 0.012
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
YL++ G V + + IA + I G L G K+ I+ GL+ L + +G
Sbjct: 21 YLRIFGAAGQV-LGMLIATFALAQFVFSPIAGNLSDLYGRKNLIIFGLILTGLAQIGFGL 79
Query: 330 GSRTWMMWAAGVLAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
+ WM++ A L LGS P I A+V+ + + +G M+ +GP +
Sbjct: 80 STDVWMLFLARFLGGLGSAFVAPPIMAFVADVTTYEERGKGMSMLGAAMSFGFMIGPGIG 139
Query: 389 GVI 391
G +
Sbjct: 140 GFL 142
>UniRef50_Q8KDQ3 Cluster: Drug resistance protein, putative; n=10;
Chlorobiaceae|Rep: Drug resistance protein, putative -
Chlorobium tepidum
Length = 422
Score = 72.9 bits (171), Expect = 2e-11
Identities = 86/378 (22%), Positives = 158/378 (41%), Gaps = 26/378 (6%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+ + L+ +G++ +P++ F++ GLI I + F+ +P+ G LSD GR
Sbjct: 11 LTVLLDLIGFGIV-LPLLPTYAKELGASPFMI-GLIASIYSTMQFIFSPIWGKLSDKIGR 68
Query: 102 KFFLLVTVFFTCAPIPLMT--INTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRA 159
+ +L ++F T + + S+SG+ + + A + DVT RS A
Sbjct: 69 RPVMLSSIFLTLVSYVFFSKAVTIPLLILARSLSGIGSANIAAAQAAITDVTDSKSRSGA 128
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGES---LXXXXXXXXXXXXXFFIM---------- 206
G++ A F +I P +G LM +G S L F++
Sbjct: 129 MGMLGAAFGIGFIIGPLVGGVLMTNFGISMVGLFAAGLNFINFTLALFLLNETNPHTEGF 188
Query: 207 VAVPESLPEKVRPTGWGPVISW-EQADPFA-ALRKVGAERTVLMLCVAVFLSYLPEAG-Q 263
+++ PE V T S ++ +A + +V + R V +L + F+ L Q
Sbjct: 189 LSLFRKNPESVVHTNNSLFASLAHKSSAYADKIHEVFSSRPVALLMIINFIYTLAIVNMQ 248
Query: 264 YSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEML 322
S I ++ V QV A VG ++ VQ V+L + ++ G +++G + +
Sbjct: 249 VSAILLWSD-VYHATEQQVGYLFAYVGFFTVIVQGVMLPKMTRNYGEHKLMVLGHITSFI 307
Query: 323 QLMWYGFGSRTWMM---WAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRG 378
+ + F T + A + A+G S+ P + +S+ S +QG + G V
Sbjct: 308 GVFFIPFIPVTSLFTVGLAILLFFAIGTSLVNPLNISMISLYSYKQKQGQIMGFAQSVNA 367
Query: 379 LCNGLGPAMFGVIFYLFH 396
L LGP +++ H
Sbjct: 368 LARILGPFSGSILYGYDH 385
>UniRef50_Q846S5 Cluster: Adventurous gliding motility protein P;
n=3; Cystobacterineae|Rep: Adventurous gliding motility
protein P - Myxococcus xanthus
Length = 371
Score = 70.5 bits (165), Expect = 9e-11
Identities = 43/141 (30%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
++ L+ +G+L +P + V F F + GL++ + ++ +SAP++G LSD +GR+
Sbjct: 13 IVALDLIGFGIL-IPQLGVYGVRFGASPFTV-GLLISVFSLMQLVSAPILGRLSDRYGRR 70
Query: 103 FFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAY 160
LLV+ + L + F I G+ S A VAD+TT +R+R
Sbjct: 71 PVLLVSQVGSLLAYLLFAFAQSLPLLFLARVIDGISGGNISTAQAVVADITTPKDRARGM 130
Query: 161 GLVSATFAASLVISPALGAYL 181
G++ A F V+ PALG +L
Sbjct: 131 GVIGAAFGLGFVLGPALGGFL 151
>UniRef50_P39637 Cluster: Uncharacterized protein ywfA; n=2;
Bacillus|Rep: Uncharacterized protein ywfA - Bacillus
subtilis
Length = 412
Score = 70.1 bits (164), Expect = 1e-10
Identities = 76/348 (21%), Positives = 147/348 (42%), Gaps = 15/348 (4%)
Query: 53 LLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLL--VTVF 110
L+ P++ L F ++ L + I G++ F+ APL+ L D + R+ LL + +F
Sbjct: 35 LVISPLLPDLAKAFSSDVSVL-ALSISIYGVMIFIGAPLLVPLGDKYSRELSLLAGLMIF 93
Query: 111 FTCAPIPLMTINTWWFFAMISISGVFAVTF-SIVFAYVADVTTEAERSRAYGLVSATFAA 169
I + N ++FF ++SG+ A F +A V D R + GL+ ++++
Sbjct: 94 IIGTVICALAQNIFFFFLGRALSGLAAGAFVPTAYAVVGDRVPYTYRGKVMGLIVSSWSL 153
Query: 170 SLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWE 229
+L+ LG+++ G L +++ + + + G E
Sbjct: 154 ALIFGVPLGSFI----GGVLHWRWTFWIFALMGVLVVLLILLEMRRHAQHKNSGKEEIEE 209
Query: 230 QADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIV 289
A F KV R + + + F + + G YS + YL+ V G +FI I
Sbjct: 210 PAGTFRDALKV--PRVPVYITIT-FCNMIGFYGMYSFLGTYLQDVFTGGNTAAGLFIMIY 266
Query: 290 GVLSIGVQVILGFLMKSLGAKHTIMV--GLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS 347
G+ + VI G + +G ++++ G++ +L + Y S ++ + + + S
Sbjct: 267 GI-GFSMSVITGKIADRIGKMRSLLIALGVISVLLACLPYAPASMFLLIASLFIWGLMQS 325
Query: 348 ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
+T +S +S S R G V + L LG A+ G ++ +
Sbjct: 326 LTVTLLSTILSDCSERHR-GKVMVFYSLASNLAVTLGSALMGPVYVAY 372
>UniRef50_A5B1K4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 467
Score = 69.7 bits (163), Expect = 2e-10
Identities = 61/256 (23%), Positives = 115/256 (44%), Gaps = 17/256 (6%)
Query: 73 MNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTW-------- 124
+NGL + GI + P++G L+D +GRK L+V F A +P+ + W
Sbjct: 48 INGLQQTVVGIFKMVVLPVLGQLADEYGRKPLLMVPYVFI-AHVPVSAVLAWNKSKGFVY 106
Query: 125 WFFAMISISGVFAV--TFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLM 182
++ + ++S + + F I AYVADV +++R+ A+ ++ F+AS V+ L +L
Sbjct: 107 AYYVLRTVSYILSQGSIFCISVAYVADVVEDSKRAAAFSWITGIFSASHVLGNVLARFLP 166
Query: 183 DLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFA---ALRK 239
+ Y + F++ V + + TG + Q + A
Sbjct: 167 EKYIFEVSIALLIFGPVYMQLFLVETVRRAPRQDQHSTGCTKIFKVLQERCLSMKHAATL 226
Query: 240 VGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVI 299
V + T+ + + F L +G + YLK GF Q++ + +VG+ SI Q
Sbjct: 227 VLSSPTLKGISIISFFYELGMSGISGVLLYYLKAAFGFNKNQLSEILMMVGIGSIFSQ-- 284
Query: 300 LGFLMKSLGAKHTIMV 315
G +M+ + K ++++
Sbjct: 285 -GKIMRYIXIKPSLVI 299
>UniRef50_Q550B7 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 463
Score = 69.7 bits (163), Expect = 2e-10
Identities = 67/323 (20%), Positives = 132/323 (40%), Gaps = 11/323 (3%)
Query: 79 GIKGILSFLSAPLIGALSDVWGRKFFL-----LVTVFFTCAPIPLMTINTWWFFAMISIS 133
G+ + FL PL G LSD +GRK L L+ + I + T N ++F+ SI+
Sbjct: 92 GLPYLSMFLLGPLFGVLSDRFGRKPILFGSVALLIIDMISCYITVRTNNLYYFYFFHSIA 151
Query: 134 GVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXX 193
GV ++++D++ E+ Y L+ A+ ++ P+ Y+
Sbjct: 152 GVCNSVAGAAHSFISDLSDESHIPILYSLLGASLGCGILFGPS--TYVFTSKSSIPYLTL 209
Query: 194 XXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAER-TVLMLCVA 252
I++ + E + V ++PF ++ + + T L L +
Sbjct: 210 YISIAIVASTLILIPFLKESLETAKQENKITVDIKNTSNPFKLIKNLFTKSGTYLSLVLL 269
Query: 253 VFLSY-LPEAGQYSCIFVYLKLVMGFGVVQVAIFI-AIVGVLSIGVQVILGFLMKSLGAK 310
+++S S F YL+LV G+ +F A+ G++ I ++ FL+K +
Sbjct: 270 LYISISYTSQDLLSTYFYYLELVYGWNASDCGLFFGALGGIIMIWGVFLIPFLLKFYSER 329
Query: 311 HTIMVGLLFEMLQLMWYGF-GSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVV 369
I +G ++ ++ G ++ GV A + A +S ++ ++ QG V
Sbjct: 330 KIISLGFSISIVAHTFFVLSGKSQYIYIVGGVFVAFVPNNISLLQAVISRSTSSELQGTV 389
Query: 370 QGMVTGVRGLCNGLGPAMFGVIF 392
V + + + +G + IF
Sbjct: 390 LTGVVAIGSIASFVGAIVSNDIF 412
>UniRef50_Q67MU6 Cluster: Putative multidrug efflux protein; n=1;
Symbiobacterium thermophilum|Rep: Putative multidrug
efflux protein - Symbiobacterium thermophilum
Length = 410
Score = 69.3 bits (162), Expect = 2e-10
Identities = 78/361 (21%), Positives = 147/361 (40%), Gaps = 25/361 (6%)
Query: 42 VVIFLEFFAWGLLT--MPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
+ +F+ AW ++ MP+ + + GL+ + S L+AP+ GAL D W
Sbjct: 22 IAVFIAASAWTMVMPFMPVFLSEDLGVGAGVTVWAGLLGAVNSGFSALTAPIWGALGDRW 81
Query: 100 GRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERS 157
GRK ++ F + LM N + + + G A VA T E
Sbjct: 82 GRKAMMVRAGIFLGSAYVLMAFVRNPYELLGVRVMIGALTGFIPTATALVATTTPERHMG 141
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV 217
+A LV+ A ++ P LG +L DL G ++ AV E
Sbjct: 142 QALSLVATGNQAGSILGPMLGGFLADLIGIRNTMALSGVAVFAATLLVVFAVREQFQRPA 201
Query: 218 RPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF 277
R + A + +R+V ++++ L + ++ + +++ ++G
Sbjct: 202 R----------QPAHFLSDMRQVLQGGPLIVVLAMSLLLQMSQSAMEPVLIPHIRQLLGS 251
Query: 278 GVV--QVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGL----LFEMLQ-LMWYGFG 330
G + ++ G+ + L + G T+ +GL LF + Q L+ G G
Sbjct: 252 GSPNWMAGVIYSVPGIAFVLAAPSWARLGERWGYTTTVTIGLAGGALFTLPQALVQSGLG 311
Query: 331 SRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
++ + +AG+ AL ++T P ISA ++ + +++G G+ + LGP + GV
Sbjct: 312 MGSFRL-SAGL--ALAAVT-PGISALIAASVPREQRGKAFGLNQSAFNVGAMLGPLLGGV 367
Query: 391 I 391
+
Sbjct: 368 L 368
>UniRef50_UPI00015B5592 Cluster: PREDICTED: similar to GA19110-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19110-PA - Nasonia vitripennis
Length = 451
Score = 68.9 bits (161), Expect = 3e-10
Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Query: 60 SVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK--FFLLVTVFFTCAPIP 117
S+LNA +T L G + + L FL +P+IGALSDV+GRK L +T +
Sbjct: 73 SLLNAPDNVNTVLFGGFLGSLYSFLQFLGSPIIGALSDVYGRKPLMILCLTGIALSYLLW 132
Query: 118 LMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPAL 177
++ N F + G+ ++ A ++DVT+ A R RA LV F+ V+ P +
Sbjct: 133 ALSSNFGLFILARVLGGISKGNVNLSMAIISDVTSPASRGRAMALVGIAFSVGFVLGPMI 192
Query: 178 GA 179
GA
Sbjct: 193 GA 194
>UniRef50_A7HKI1 Cluster: Major facilitator superfamily MFS_1; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Major facilitator
superfamily MFS_1 - Fervidobacterium nodosum Rt17-B1
Length = 407
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/379 (21%), Positives = 162/379 (42%), Gaps = 25/379 (6%)
Query: 22 MKDGIMTMSGIGEPS-VFHALV-VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMG 79
M++ + +++GI + V L ++F + +GL+ +P++ F ++ L M
Sbjct: 1 MEEKLSSINGIDKTKKVLTTLFFIVFADMLGFGLI-IPLLPYYAKEFGAKDIVIGFLSM- 58
Query: 80 IKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFA 137
I + ++PLIG +SD +GRK LL++V T + L+ IS + G+
Sbjct: 59 IYPLGQIFASPLIGRMSDKFGRKIALLLSVGGTFLSLLLLGFAKSLTLIFISRLLDGLTG 118
Query: 138 VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXX 197
++ +Y++D T + R+++ GL+ A F ++ PA+G +L +G +
Sbjct: 119 GNITVAQSYISDFTDKKSRAKSLGLIGAAFGLGFILGPAIGGFL-SRWGFHVPAFFAAGL 177
Query: 198 XXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSY 257
I+ +P+S P V P F ++K + V L + F
Sbjct: 178 SFVNLLNIIFLLPDSKP--VEDAKRVPF-------TFEEMKKTISRPVVFYLLLTKFFYS 228
Query: 258 LPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKH---TIM 314
S ++ + + Q + +A VG+L Q GFL+ + K+ I+
Sbjct: 229 FGFTTFESTFALFALRRLNLPLSQTSFVLAYVGILIAFTQ---GFLVGKITKKYKEDDII 285
Query: 315 VGLLFEMLQ-LMWYGFGSR-TWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGM 372
L+F ++ L+ Y F + ++ L+ + + ++++ + DR G G+
Sbjct: 286 KSLIFVVVPFLILYSFSANLITLILLLTPLSVISGLIGVSVNSIATKTVERDRLGGTLGI 345
Query: 373 VTGVRGLCNGLGPAMFGVI 391
V L + P +FG +
Sbjct: 346 FNSVDSLTRIISP-LFGAL 363
>UniRef50_A3I0S1 Cluster: Multidrug transporter, putative; n=1;
Algoriphagus sp. PR1|Rep: Multidrug transporter,
putative - Algoriphagus sp. PR1
Length = 408
Score = 68.9 bits (161), Expect = 3e-10
Identities = 42/157 (26%), Positives = 79/157 (50%), Gaps = 14/157 (8%)
Query: 41 LVVIFLEFFAWGLL--TMPII------SVLNATFPD-HTFLMNGLIMGIKGILSFLSAPL 91
L+ +FL+ G++ MP + S+L + + +M GL++G ++ F AP+
Sbjct: 16 LLTVFLDMLGVGIIIPVMPALFFQPDSSILPVMASEAYRSIMFGLLVGCYPLMQFFGAPI 75
Query: 92 IGALSDVWGRKFFLLVTVF-----FTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAY 146
+GALSD +GRK L++++ + ++ N W F + G SI +
Sbjct: 76 LGALSDRFGRKKMLILSIIGVLIGYLLFAWAIIIKNLWLLFFSRLLPGFAGGNVSIAMSA 135
Query: 147 VADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
++D++ E E+++ +GL F ++ PALG +L D
Sbjct: 136 ISDISEEKEKTKNFGLAGMAFGIGFILGPALGGFLGD 172
>UniRef50_Q89NI8 Cluster: Bll3850 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll3850 protein - Bradyrhizobium
japonicum
Length = 408
Score = 68.5 bits (160), Expect = 4e-10
Identities = 79/361 (21%), Positives = 155/361 (42%), Gaps = 23/361 (6%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
VV+ ++ G++ +P++ + F + LI + + ++ P++G LSD +GR
Sbjct: 26 VVVAVDATGMGII-LPLLPFYSQRLGATPFQLGALI-SVYAVCQLVAGPVVGMLSDRYGR 83
Query: 102 KFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRA 159
+ LLV+ T L+ + N F I G+ + S+ AY A+ + A R +A
Sbjct: 84 RKVLLVSQIGTFIGFVLLAVAGNLTMVFLARIIDGLTSGNISVAHAYAAEHSAPATRKQA 143
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRP 219
G+ S L++ PAL ++L+ YG++ F + +P P
Sbjct: 144 LGMTSGAIGTGLLLGPALSSFLVH-YGQTAPVWAAAALSLISIFATIALLPPDHPAS--- 199
Query: 220 TGWGPVISWEQADPFAALRKVG---AERTVLMLCVAVFLS--YLPEAGQY-SCIFVYLKL 273
P+ +P +G A R + +L V F++ +L + G + S F +
Sbjct: 200 ---EPLYQHRVPEPTLTRSLLGMRYAWRLLGLLIVFFFVNSMFLSQIGLFLSARFSWDG- 255
Query: 274 VMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF--GS 331
FG ++ A G +++ VQ +L +L A +V F + L + G G+
Sbjct: 256 -HPFGARELGWMFAYAGFINMMVQGLL-IARANLIASDRAIVMAAFACMGLGFAGLAAGN 313
Query: 332 RTWMMWAAGVLAALGSI-TYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
++ L +G++ ++A +S ++ +RQG++ G+ + N P + G
Sbjct: 314 NVSLLAIYLTLIIVGTMFARSTLTAELSRSTAVNRQGMIMGLNQSLMSGANISAPLLSGA 373
Query: 391 I 391
+
Sbjct: 374 L 374
>UniRef50_Q54N46 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 560
Score = 68.5 bits (160), Expect = 4e-10
Identities = 72/317 (22%), Positives = 134/317 (42%), Gaps = 31/317 (9%)
Query: 83 ILSFLSAPLIGALSDVWGRKFF-----LLVTVFFTCAPIPLMTINTWWFFAMISISGVFA 137
I F L G LSD +GRK ++V + + + T N ++++ + SI+G +
Sbjct: 171 ISMFCFGALGGVLSDKFGRKLMFYYGTIMVILDMVSCYVTIRTNNLYYYYVVHSIAGTYN 230
Query: 138 VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAY-------LMDLYGESLX 190
V + V++Y+AD++ E Y L+ + +V+ P + L S+
Sbjct: 231 VALAAVYSYIADISEEHAVPYLYSLIGVSLGLGVVLGPVISVASTFHETPQQQLDHLSMS 290
Query: 191 XXXXXXXXXXXXFFIMVAVPESLP-----EKVRPTGWGPVISWEQADPFAALRKVGAERT 245
FI+ + ESL K+R T ++PF ++ + +
Sbjct: 291 SLYIGCGLVACSLFIIPFLKESLTIAKENHKIRQTK-------SSSNPFKLIKLIFSANG 343
Query: 246 VLMLCVAVFLSY-LPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVIL-GFL 303
+ + ++ S E ++ + + +LV + + ++ VG+L I +IL L
Sbjct: 344 YVAFVIILYTSISYTEQDVFTTYYYHNELVYNWDGTYNSFYMGGVGILMIIWSLILIPIL 403
Query: 304 MKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAA-LGSITYPAISAYVSVNSR 362
+K + I VG L L + YGF W+ +G++AA + +I Y SV SR
Sbjct: 404 LKRYSERKLISVGFLVGALTHVSYGFAYNQWIWIGSGIVAAFVPNILY----LLQSVISR 459
Query: 363 ADRQGVVQGMVTGVRGL 379
A + ++TG R +
Sbjct: 460 ATPPEIKGSILTGSRAI 476
>UniRef50_Q63BE3 Cluster: Multidrug resistance protein; n=3;
Bacillus cereus group|Rep: Multidrug resistance protein
- Bacillus cereus (strain ZK / E33L)
Length = 400
Score = 67.7 bits (158), Expect = 6e-10
Identities = 71/287 (24%), Positives = 121/287 (42%), Gaps = 21/287 (7%)
Query: 53 LLTMPIISVLNATF--PDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF-----FL 105
LL P++ V+ T PD + GL++ I + ++AP+ G +SD GRK F+
Sbjct: 24 LLVAPLLPVITETISIPDGS---GGLLITIYALCYGITAPVFGMMSDRVGRKRMIIIGFI 80
Query: 106 LVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSA 165
+ ++ C + F + +SG A+ +FA V D T R +A G +
Sbjct: 81 IFSISTFCTGLAKNFEILLLFRGLTGLSG--AMIMPSIFALVGDKVTYESRGKAMGTIMG 138
Query: 166 TFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL-PEKVRPTGWGP 224
S VI +GA+L ++ F+ + + L EK R
Sbjct: 139 AMIGSTVIGVPIGAFLSEIGN----WQWTFYSIGLLTLFLTLLINHILRNEKERDD--VH 192
Query: 225 VISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAI 284
V E D A L+ +VL +A FL + G +S I VY + G V ++ I
Sbjct: 193 VSLTETVD--APLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENNFGISVGKIGI 250
Query: 285 FIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGS 331
I + GV S+ ++ G L +G K+ I++ + + +M + +
Sbjct: 251 VIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLST 297
>UniRef50_Q9K9Q3 Cluster: BH2592 protein; n=2; Bacillus|Rep: BH2592
protein - Bacillus halodurans
Length = 409
Score = 67.3 bits (157), Expect = 8e-10
Identities = 79/362 (21%), Positives = 142/362 (39%), Gaps = 22/362 (6%)
Query: 42 VVIFLEFFAWGLLTMPI------ISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGAL 95
+++ +F +TM I + L T P L G+I + +FL +PL L
Sbjct: 10 ILVVCQFLVVSAMTMIIPFLPLYLQELGVTDPSEVSLWAGIIFAANFLTAFLFSPLWSRL 69
Query: 96 SDVWGRKFFLLVTVFFTCAPIPL--MTINTWWFFAMISISGVFAVTFSIVFAYVADVTTE 153
+D +GRK +L + F I L + ++GV + VA T +
Sbjct: 70 ADRYGRKMMILRSGFGMALIIGLTGFAQGPLSLLCLRLLNGVISGFIPASIGLVATNTPK 129
Query: 154 AERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL 213
+ A G + A + + P +G + +G + +++ V E
Sbjct: 130 EKAGYALGFLQAGAVSGGICGPLIGGIMAQAFGYRMIFFLTGLCIFIAALVVLLFVNEQ- 188
Query: 214 PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL-K 272
+ P E+ + + +K+ A R + L V VFL G I +++ +
Sbjct: 189 --------FTPNPKEEKTNTWGEFKKITAIRPIFSLYVVVFLIQFAVMGVNPLISLFVEE 240
Query: 273 LVMGFGVVQVA-IFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGS 331
LV G V A + I+ G ++ + LG L GA H + LL ++ ++ F
Sbjct: 241 LVSGVNVALFAGLAISATGFANMLSSMQLGKLSDKAGAHHVLFFCLLGTVIFMIPQAFVQ 300
Query: 332 RTWMMWAAG--VLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
+ W + V +LG + PA +A V +++ + G T L N +GP + G
Sbjct: 301 QLWQLIVLRFFVGLSLGGL-LPAANALVRMHAPKGMESRTYGFSTSALYLGNMVGPTVGG 359
Query: 390 VI 391
+
Sbjct: 360 AV 361
>UniRef50_A7HUQ1 Cluster: Major facilitator superfamily MFS_1; n=1;
Parvibaculum lavamentivorans DS-1|Rep: Major facilitator
superfamily MFS_1 - Parvibaculum lavamentivorans DS-1
Length = 449
Score = 66.9 bits (156), Expect = 1e-09
Identities = 84/341 (24%), Positives = 147/341 (43%), Gaps = 32/341 (9%)
Query: 76 LIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF---FTCAPIPLMTINTW--WF---- 126
+I + L L++ G SDV GRK +L+ VF F+ + + + + + W
Sbjct: 76 MIFSLSAALWVLTSTFWGRRSDVMGRKPVILIGVFGFAFSTSLVGFVLLAGYQHWISMVL 135
Query: 127 -FAMI----SISGVFAV-TFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAY 180
F ++ +I G+F + AYVAD TT AER+ + + A F V+ P + A
Sbjct: 136 MFPLVMGARAIFGIFGSGSMPASQAYVADRTTRAERAGSIAQIGAAFGLGTVVGPGIAAA 195
Query: 181 LMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKV 240
+++ F +A+ LPE+ RP ++S E+ + AAL K
Sbjct: 196 FAEIH-----ILAPFFAVGALAFVSGIAIWILLPERTRPK---KMLS-EKQEKQAAL-KW 245
Query: 241 GAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVI- 299
A + L + V LS L ++ YL +G + ++ VG++++ + +
Sbjct: 246 SAPNVMPWLVIGVILS-LSQSIMMQLFAFYLMAELGMQGSEATQLVS-VGMMAMAMATLV 303
Query: 300 --LGFLMK-SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISA 355
LG + + L + + G + +L FG ++ +A LA LG +SA
Sbjct: 304 AQLGLIQRFDLSVQFLLRWGAVTMILSFAMLVFGGSYGVLVSALALAGLGFGFLRSGLSA 363
Query: 356 YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFH 396
S++ QG V G++ + L PA+ +FYL H
Sbjct: 364 GASLSVSLKDQGAVAGLIGSTAATGHILNPAIGIPLFYLLH 404
>UniRef50_A7RGX9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 470
Score = 66.9 bits (156), Expect = 1e-09
Identities = 77/344 (22%), Positives = 148/344 (43%), Gaps = 26/344 (7%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS 131
L G++ + +L F+ PLIGA SD++GR+ LL+++ + ++ + +I+
Sbjct: 109 LFGGVVGSLFSLLQFICCPLIGAASDLFGRRITLLLSMIGVLFSYVIWAVSKNFTIFVIA 168
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGA-YLMDLYGES 188
I G+ +I A V DVT+ RS+ LV ++ ++ P +GA + G S
Sbjct: 169 RVIGGLCKGNVTICTAAVTDVTSSKTRSKGMALVGVAYSIGFIVGPMIGAVFASKSSGSS 228
Query: 189 -----LXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGP-------VISWEQADPFAA 236
L + + E+LP + R I+ F+A
Sbjct: 229 EPFYQLPALFAIVLSAVDIVIVFLFFKETLPTEKRAKSLIHECQKSLLYINPVSLFKFSA 288
Query: 237 LR-KVGAE-RTVLMLCVAVFLSYLPEAG-QYSCIFVYLKLVMGFGVVQVAIFIAIVGVLS 293
L AE +TV + FL +G +++ F+ K + Q +F + V++
Sbjct: 289 LEGSSDAELQTVRAIGRVYFLFLFFFSGLEFTLTFLTHKNFQYTSMNQGMMFFYVGSVMA 348
Query: 294 IGVQVILGFLMKSLGA---KHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-IT 349
+ G ++ L A K T + G+ + ++ G T++++A L + GS +
Sbjct: 349 ----TVQGGYVRRLPAGAEKKTAVQGIAVIIPGMILVGLAKTTFILYAGLTLFSYGSAVV 404
Query: 350 YPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
P ++A +S D++G V G+ + L G+ P +F +++
Sbjct: 405 VPCLTALISRYGSEDQKGRVMGIFRSLGALARGIAPFVFCTVYW 448
>UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1;
Picrophilus torridus|Rep: Tetracycline resistance
protein - Picrophilus torridus
Length = 384
Score = 66.9 bits (156), Expect = 1e-09
Identities = 74/365 (20%), Positives = 159/365 (43%), Gaps = 28/365 (7%)
Query: 34 EPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIG 93
+ + V ++F +G++ +PI F + L++ + + F+++P +G
Sbjct: 2 DKGILPLFVTAMIDFIGFGII-IPIAPFYTRDLGATPFEFSILLV-VYSLAQFIASPYLG 59
Query: 94 ALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMI--SISGVFAVTFSIVFAYVADVT 151
LSD GRK L++ + A + ++ I +I+G + +++++V+D T
Sbjct: 60 RLSDRIGRKNVLVLGLSGEIAGYLIFGLSPVLSLLYIGRAITGATSGNLPVIYSFVSDKT 119
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
+ R+RA G++ A VI P +G L ++G + FI + +
Sbjct: 120 SSDNRTRAIGMIGAAIGIGFVIGPFIGGSL-SIFGYRVPILFAAVLS-----FINMVLVL 173
Query: 212 SLPEKVRPTGW--GPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV 269
+ E+ + T + G ++ + P+ + T + L + + L GQ
Sbjct: 174 RIKEERKKTNYKKGSILKAFEIAPY-----IFISITFIALGFVMLQTTLAYYGQ------ 222
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGF-LMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ +G + V I + IVG+ Q++L F L + +G+ T+M+G++ + +
Sbjct: 223 ---ALYSWGSLAVGIILGIVGMEQALFQLLLVFRLTRRIGSIRTVMLGIISFTMAFLILS 279
Query: 329 FGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAM 387
F ++ + L +LG S+ + + +S + + +G G+ + L N +GP +
Sbjct: 280 FRVNEYIAIFSLTLFSLGYSLFQTPVISIISDIAPVEIRGSTLGITQSAQSLSNIIGPLI 339
Query: 388 FGVIF 392
G F
Sbjct: 340 AGYTF 344
>UniRef50_A3CSK5 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Methanoculleus marisnigri JR1|Rep: Major
facilitator superfamily MFS_1 precursor - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 397
Score = 66.9 bits (156), Expect = 1e-09
Identities = 84/363 (23%), Positives = 150/363 (41%), Gaps = 19/363 (5%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDH---TFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
V+F+ FA +L + I+S L + ++ T + G+I + + P+IG +SD
Sbjct: 10 VLFISVFAT-MLGLGIVSPLLPIYAENLGATGIWLGIIFSAFALSRSVFMPVIGRISDRR 68
Query: 100 GRKFFLLVTVF-FTCAPIPLMTINTWWFFAMISISG--VFAVTFSIVFAYVADVTTEAER 156
GRK+ +L+ +F + + + +++ + + + A+ I AYVAD++ +
Sbjct: 69 GRKWIILIGMFAYAVLSLAYIIVDSVYSLTAVRFAHGLASAMVVPIAMAYVADLSEKGRE 128
Query: 157 SRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEK 216
G S + + + P LG +L D +G L I+V + SLPE
Sbjct: 129 GSHMGNFSISMFLGMGMGPLLGGFLNDAFG--LDSVFYVMAGLSAFATILVGI--SLPEA 184
Query: 217 VRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMG 276
R T + ++ +P +RK+ + + V F+S L G I V+ L+
Sbjct: 185 KRGT-----FTVQEGNP-VPMRKILTLPVMRGVMVFAFISALGRGGMMVFIPVFGPLI-A 237
Query: 277 FGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGF-GSRTWM 335
+V I ++ L +QV +G + + I+ G L + F GS +
Sbjct: 238 ISPTEVGIVLSANTFLMALLQVPMGRITDTGNKVVLIVAGSAITALAIGAIPFSGSFGPL 297
Query: 336 MWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
+ ++ G+I PAI A R G G V G+ + P M GV
Sbjct: 298 LAITSLVGIGGAIQQPAIMALTVDAGRTIGMGTSMGAYNTVFGIGMIIAPLMGGVFMDYI 357
Query: 396 HVD 398
+D
Sbjct: 358 GID 360
>UniRef50_A0B6G9 Cluster: Major facilitator superfamily MFS_1; n=1;
Methanosaeta thermophila PT|Rep: Major facilitator
superfamily MFS_1 - Methanosaeta thermophila (strain DSM
6194 / PT) (Methanothrixthermophila (strain DSM 6194 /
PT))
Length = 387
Score = 66.5 bits (155), Expect = 1e-09
Identities = 86/362 (23%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGAL 95
S+F + +F+ + ++ PI L T LM G+I+ I G + L+ G L
Sbjct: 7 SIFPLYLSVFVSVLGFAVVA-PIFP-LYVLDMGATHLMLGMIISIYGAVQLLTQMPAGRL 64
Query: 96 SDVWGRKFFLLVTVF-FTCAPIPLMTINTWWFFAMISISGVF--AVTFSIVFAYVADVTT 152
SD GRK LL+ + FT P+ + + + +I I G ++ + + A + D
Sbjct: 65 SDQRGRKPVLLIGLLTFTIMPLLYIYASNAYQLLLIRIFGGIGASMVWPVTMALIVDCVD 124
Query: 153 EAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
+ R A G +A+F +++ + P +G+ L +G + + V E
Sbjct: 125 PSHRGLAMGWYNASFYSAVAVGPVIGSLLYGSFGINAPFIFWSLFAVASLIMVTFVVRE- 183
Query: 213 LPEKVRPTGWGPVISWE-QADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
P G V+S P A L G+ T ++ C V + + G + L
Sbjct: 184 ------PPVRGEVLSTNTPRTPKARLIVDGSMITFIICCSVVMVPGI-IGGFNMTLLPEL 236
Query: 272 KLVMGFGVVQVAI-FIAIVGVLSIGVQVILGFLMKSLGAKHTIMV-GLLFEMLQLMWYGF 329
L +G GV Q+ I ++A G ++ + G + LG + ++ G L +L + G
Sbjct: 237 ALSVGVGVSQLGILYMAYAGSNAL-ANIYFG-RVADLGHRRLLISGGSLGCVLGFLVLGH 294
Query: 330 GSRTW-MMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
G + A +L I PA + VS + +R+G + G+ R L +GP +
Sbjct: 295 GQGILPQLIALTILGLSSGICTPAATVVVSYITSPERRGEIFGIFNTSRMLGVVIGPIIA 354
Query: 389 GV 390
G+
Sbjct: 355 GL 356
>UniRef50_UPI0000E4A5F1 Cluster: PREDICTED: similar to MGC84630
protein, partial; n=4; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to MGC84630 protein,
partial - Strongylocentrotus purpuratus
Length = 396
Score = 65.7 bits (153), Expect = 3e-09
Identities = 44/188 (23%), Positives = 81/188 (43%), Gaps = 11/188 (5%)
Query: 69 HTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL--MTINTWWF 126
++ L G++ + +L F+++P+IGA SDV+GR+ +LVT+ L M+ N F
Sbjct: 94 NSVLFGGVLGSLFSLLQFVTSPVIGAASDVYGRRSVMLVTMVGIALSYVLWAMSYNFGIF 153
Query: 127 FAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLM---D 183
+ G+F S+ V D++T R + ++ F+ ++ P +GAY
Sbjct: 154 VLARIVGGIFKGNVSLSTTIVTDISTTKNRGKGMAMIGLAFSVGFIVGPMIGAYFATKGG 213
Query: 184 LYGESLXXXX----XXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQ--ADPFAAL 237
L+ + F+ + E+LP++ R G Q +PF+
Sbjct: 214 LFADGAWAVTPALLALTLSIADLLFVFAFLKETLPQEKRAPSMGNSFQERQNLINPFSLF 273
Query: 238 RKVGAERT 245
R + T
Sbjct: 274 RFSAVKNT 281
>UniRef50_A4SRL1 Cluster: Major facilitator superfamily permease;
n=2; Aeromonas|Rep: Major facilitator superfamily
permease - Aeromonas salmonicida (strain A449)
Length = 412
Score = 65.7 bits (153), Expect = 3e-09
Identities = 77/315 (24%), Positives = 139/315 (44%), Gaps = 30/315 (9%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWF---FAMIS 131
G+IMG+ + + +P +G LSD GRK L V + LM + W ++S
Sbjct: 57 GVIMGLYPLFQLVGSPWLGRLSDRHGRKPILTVCLVGVLVGYALMALGIAWRSLPLLLLS 116
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGE-S 188
+ G F +IV A AD++T ++R++ ++ V+ P +G Y + G+ S
Sbjct: 117 RVVEGFFNGDIAIVQAMAADMSTTKTKARSFAWINIGMNLGWVLGPMIGGYAAVVSGDYS 176
Query: 189 LXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLM 248
L ++ +P P V P+ Q P + R++ + +L
Sbjct: 177 LAAWLAVAMTLVNLLLVLWLLPNKAP--VAPS---------QQAPSLSSRQLLLQPALLP 225
Query: 249 LCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQV---AIFIAIVGVLS--IGVQVILGFL 303
V LSY ++ V+L + + VQ+ A+ +++ +L +G ++ +
Sbjct: 226 YFVLTLLSYGAVQLYFTYFNVWLVERLAWDPVQLAQAAVLVSVPMMLGSWLGSRLARHWR 285
Query: 304 MKSLG-AKHTIM-VGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNS 361
SLG H +M G+L +L W+G + T++ G+ +LG + A S VS S
Sbjct: 286 GSSLGVVGHLVMAAGMLMFVLPDHWWGL-ALTFI--PVGIGMSLGEL---ATSVAVSNRS 339
Query: 362 RADRQGVVQGMVTGV 376
A++QG G+ G+
Sbjct: 340 HAEQQGQAMGIYRGL 354
>UniRef50_Q398I1 Cluster: Major facilitator superfamily (MFS_1)
transporter; n=8; Burkholderia cepacia complex|Rep:
Major facilitator superfamily (MFS_1) transporter -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 416
Score = 65.3 bits (152), Expect = 3e-09
Identities = 69/313 (22%), Positives = 120/313 (38%), Gaps = 17/313 (5%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTW-----WFFAM 129
GL GI + F + L+G LSD +GR+ LL+ V A +M W A
Sbjct: 56 GLGYGIYPLCMFFGSSLMGDLSDRYGRRRILLLCVLGLAAGYAMMAAGAWHASVALLLAG 115
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
++G+ A I A + D++T ++ ++S F+A +++ P LG D L
Sbjct: 116 RGLTGLMAGCQGIAQAAITDLSTPENKAYNMSIMSLAFSAGVIVGPVLGGVTSDRTISPL 175
Query: 190 XXXXXXXXXXXXXFFIMVA-VPESLPEKVRPTGWGPVISWEQADPFAALRKVG---AERT 245
+ S + P G + DP LR +G +R
Sbjct: 176 FDYGTPFVLVAALSLVCAFWTWASYRDSAAPRG------DTRIDPLLPLRIIGEAARQRN 229
Query: 246 VLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSI-GVQVILGFLM 304
V L V FL + I + L+ G+ ++ +F ++G+ + G+ ++ ++
Sbjct: 230 VAFLSVVFFLMQVGYGLYLQTIMLLLQAKFGYTSARLGLFSGVIGLCFVFGLLFVVRLML 289
Query: 305 KSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWA-AGVLAALGSITYPAISAYVSVNSRA 363
+ GLL + + ++WA A V+ + Y + S
Sbjct: 290 RVWRVVDIAKAGLLVAGIGQVLSALFPHEPVLWALAMVVGCFDMVAYTTMYTAFSDAVSE 349
Query: 364 DRQGVVQGMVTGV 376
DRQG V G+ V
Sbjct: 350 DRQGWVLGVAGSV 362
>UniRef50_Q4WJ43 Cluster: Tetracycline transporter, putative; n=16;
Pezizomycotina|Rep: Tetracycline transporter, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 460
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/342 (21%), Positives = 143/342 (41%), Gaps = 20/342 (5%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWW--FFAM 129
L+ G + + +L ++AP IG LSD +GR+ LL ++ + L T + F A
Sbjct: 77 LLGGALGSLFSLLQAIAAPFIGRLSDRYGRRTALLCSMVGNTLSVALWVAATDFRTFLAS 136
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
+ G+ + A D++ E++R LV A F+ + PALGA L ++ +
Sbjct: 137 RIVGGLSEGNVQLAHAIATDISDESKRGSTMALVGACFSIAFTCGPALGAALSNITTVAA 196
Query: 190 XXXXXXXXXX-----XXXFFIMVAVPE--------SL-PEKVRPTGWGPVISWEQADPFA 235
++ +PE SL P + T + +QAD
Sbjct: 197 NPFATAAGVSLVLIVTETLYLYRCLPETHPRLTKLSLGPHRAEDTASPTQKNGKQADASN 256
Query: 236 ALRKVGAERT--VLMLCVAVFLSYLPEAG-QYSCIFVYLKLVMGFGVVQVAIFIAIVGVL 292
+ +RT +L + FL LP +G ++S F+ G A+ ++ ++
Sbjct: 257 PDSTMPRKRTNNPALLNLLHFLFLLPFSGLEFSLPFLTATFYAGSTASPSALNGRLLSLM 316
Query: 293 SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSIT-YP 351
+ ++ G +++ L T+ G++ + S +++AG L A+ S T
Sbjct: 317 GLIASLLQGTVVRRLPPLMTLRAGVVACTISFFLLARVSSLVGLYSAGALLAVTSATVVT 376
Query: 352 AISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
+++ S+ +R +G+V G + + GP +F +F+
Sbjct: 377 GLNSLGSLEAREGERGLVLGRLRSWGQVGRAAGPLLFCSLFW 418
>UniRef50_A1I922 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Major facilitator superfamily MFS_1 precursor
- Candidatus Desulfococcus oleovorans Hxd3
Length = 410
Score = 64.5 bits (150), Expect = 6e-09
Identities = 83/370 (22%), Positives = 142/370 (38%), Gaps = 21/370 (5%)
Query: 33 GEPSVFHALVV-IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPL 91
G+ +F A+ V IF G++ +P++ V F + GLI + PL
Sbjct: 7 GDKKIFAAIFVSIFGAVMGVGIV-VPLLPVYAQNLGASGFYI-GLIFAAFSLSRTFLLPL 64
Query: 92 IGALSDVWGRKFFLLVTVF-FTCAPIPLMTINTWWFFAMIS-ISGVF-AVTFSIVFAYVA 148
G+LSD GRK ++ + +F + + + +T + + G+ A+ + AY+
Sbjct: 65 FGSLSDRTGRKPYITIGLFGYALVSVAFIYSDTVGGLIWLRFLQGIASAMIMPVAQAYIG 124
Query: 149 DVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVA 208
D+T + GL + + SL I P LG + DL G +
Sbjct: 125 DITPKNREGFTMGLFNLSMFTSLSIGPLLGGVINDLAGLDAAFAGMGVLSLAACLASLFL 184
Query: 209 VPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
+P E V G P W L + R V + C+ +LP
Sbjct: 185 LPPVREEHVMTRGSVPA-KWSLLLTDRFLYGLFCLRFVYVFCIGTIWCFLP--------- 234
Query: 269 VYLKLVMGFGVVQVAIFIAIVGVLSIG-VQVILGFLMKSLGAKHTIMVGLLFEMLQLMWY 327
V+ + G ++ + I ++GV G +Q+ +G L K + G L ++ Y
Sbjct: 235 VFASSI-GLSSSRIGVLI-MLGVFVSGLLQMPMGMLADRTDQKRMAICGGLMTAGAMVVY 292
Query: 328 GFGSRTWMMWAAGVLAAL-GSITYPAISAYVSVNSRADR-QGVVQGMVTGVRGLCNGLGP 385
+ W ++AA V + G + P + A V R G V ++T + G
Sbjct: 293 TWAVDFWGLFAASVAFGIGGGVAMPPLMAMAVVKGGETRAMGSVMSLLTVAHSMGMLFGA 352
Query: 386 AMFGVIFYLF 395
A+ GV F
Sbjct: 353 AIGGVAMDFF 362
>UniRef50_Q0W0C7 Cluster: Putative permease; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative permease -
Uncultured methanogenic archaeon RC-I
Length = 435
Score = 64.5 bits (150), Expect = 6e-09
Identities = 86/364 (23%), Positives = 151/364 (41%), Gaps = 40/364 (10%)
Query: 70 TFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV--TVF---FTC-------APIP 117
T L GL+M + F+ AP+ GA+SD GRK +++ T F FT A +
Sbjct: 41 TALDLGLLMATFSAMQFVCAPVWGAISDRIGRKPVMMIGLTGFGLAFTVTGLSSEPAALA 100
Query: 118 LMTINTWW-----FFAMISISGVFAVTFS-----IVFAYVADVTTEAERSRAYGLVSATF 167
+ + W ++ IS V T S A++AD+T ER G + A
Sbjct: 101 ISEVIGHWTGLSPHIGVLFISEVIGGTLSSGIWPATLAFIADITKPEERGNLMGQMGAAS 160
Query: 168 AASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESL-----PEKVRPTGW 222
++I PA+ +L + +L + +PES PE V+
Sbjct: 161 GLGVIIGPAISGFLTS-WSLTLPFFATAGIGFLTAVLAYLLLPESRVPGQQPEVVKKVSM 219
Query: 223 GPVISWEQADPFAALRKVGAERTVLMLCVAVFL----SYLPEAGQYSCIFVYLKLVMGFG 278
I F + ++ FL + G +F +++ G G
Sbjct: 220 LSAIKTSLGFIFILTMLISFAGAMIDGTFGYFLMGKFGLSDQPGPVPLLFWTVQMT-GPG 278
Query: 279 VVQVAI-FIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLM--WYGFGSRTWM 335
V+ V F+ I GV+ G+ ++G + +LG + TI+ GL+ ++ ++ G T
Sbjct: 279 VMGVVFAFMGITGVVCQGL--LVGKAISTLGEQKTIIAGLIIYSAGIIAIYFSVGIVTLA 336
Query: 336 MWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
++ + G I +P+++ VS + DRQG + G++ L +GP G++F +
Sbjct: 337 LFTCLIEVGFGLI-FPSLNTLVSKRTDPDRQGEMLGVMGSFNSLGRVIGPPAGGLMFAV- 394
Query: 396 HVDL 399
H+ L
Sbjct: 395 HIGL 398
>UniRef50_A1ZHT1 Cluster: Major facilitator family transporter,
putative; n=3; Sphingobacteriales|Rep: Major facilitator
family transporter, putative - Microscilla marina ATCC
23134
Length = 419
Score = 63.7 bits (148), Expect = 1e-08
Identities = 71/302 (23%), Positives = 122/302 (40%), Gaps = 26/302 (8%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRK---FFLLVTVFFTCAPIPLM-TINTWWFFAMI 130
GLI+ + + + LS P G L+D GR F V F T PL+ T+ + F +
Sbjct: 75 GLIIALFTLAAGLSRPFSGKLTDTVGRIPIIVFGAVVCFLTGFLYPLLLTVGGFLFIRFV 134
Query: 131 -SISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
+S F T + AYVADV +R A G+ T I PA G+Y+ L+
Sbjct: 135 HGLSTGFTPTGTA--AYVADVVPIRKRGEAMGIFGLTNNIGTAIGPAFGSYIA-LHYPIQ 191
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVR-PTGWGPVISWEQADPFAALRKVGAERTVLM 248
I++ + E+LP+K R P W ++ D LR V T+L+
Sbjct: 192 YMFYCSSGFAILSILILIKLKETLPQKQRQPFRWS-LLKINPRD-IIELRVVAPSVTLLL 249
Query: 249 --LCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKS 306
+ L+ +P+ + G+ +F + + S+G++ + G +
Sbjct: 250 SVFSFGIILTIIPDFSDH------------LGIKNKGLFFTVFTLSSLGIRFVAGKISDR 297
Query: 307 LGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADR 365
G I VG + +++ ++ G + M+ V + I P A+ S +
Sbjct: 298 FGRVSVIKVGAIIQLISMVIIGMATTPLMLMMGAVFFGIAVGIMSPTAFAWTIDLSHDNA 357
Query: 366 QG 367
+G
Sbjct: 358 RG 359
>UniRef50_Q83X84 Cluster: Putative efflux transporter protein; n=1;
Streptomyces rochei|Rep: Putative efflux transporter
protein - Streptomyces rochei (Streptomyces parvullus)
Length = 426
Score = 63.3 bits (147), Expect = 1e-08
Identities = 76/330 (23%), Positives = 126/330 (38%), Gaps = 15/330 (4%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-----FTCAPIPLMTINTWWF 126
L GL +G + FL APL+G+LSD + RK L + + + L+ + F
Sbjct: 52 LFYGLAIGSYSLAMFLGAPLLGSLSDHFRRKKTLTLCLLGLALGYALTITALVRRDVTLF 111
Query: 127 FAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD--- 183
+ G+F+ + + A + DVT + R GL+ + V+ P +G YL D
Sbjct: 112 VVGRVVGGLFSGSLPVAQAAILDVTPKERRVNVIGLIMFCVSTGYVVGPLIGGYLSDSSL 171
Query: 184 LYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAE 243
+ SL +++ + RP G +P L +
Sbjct: 172 VSWFSLRTPFVFVAGVTVLNLLILLLTYREEPAPRPAG-----RMAFPNPVKHLMESFTF 226
Query: 244 RTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILGF 302
V +LC A+ L L + I +YL GF V I++VGV L+ ++
Sbjct: 227 PGVRVLCGALLLMSLGWTAFFQFIGLYLTANQGFDQRAVTNLISVVGVGLAAAFLSLVPL 286
Query: 303 LMKSLGAKHTIMVGLLFEMLQLMWYGF-GSRTWMMWAAGVLAALGSITYPAISAYVSVNS 361
MK L + + L + + GS+ + V AA I+Y + +S
Sbjct: 287 SMKYLKPRIAVAGALAVMTVCIAGTALTGSKAVLYVLCLVGAATYGISYSGLVGMMSGAV 346
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
QG V G + + G +FG +
Sbjct: 347 DDSHQGSVMGTAGAIAAISAGASGVVFGAV 376
>UniRef50_A4BEE3 Cluster: Major facilitator superfamily MFS_1; n=1;
Reinekea sp. MED297|Rep: Major facilitator superfamily
MFS_1 - Reinekea sp. MED297
Length = 404
Score = 63.3 bits (147), Expect = 1e-08
Identities = 80/349 (22%), Positives = 147/349 (42%), Gaps = 28/349 (8%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGIL-SFLSAPLIGALSDVWGRKFFLLV--TVF 110
+ +PI+++ D + GL +GI G+ +FL P GA SD +GRK +++ +F
Sbjct: 27 MVLPILTLYGQDLQDASPASLGLALGIYGLTQAFLQIPF-GAASDRYGRKPLIVIGLLLF 85
Query: 111 FTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAAS 170
+ + M + ++ G A++ S+V A +AD T E +RS++ ++ A AS
Sbjct: 86 MVGSIVAAMADSVTSLIIGRALQGGGAIS-SVVLALLADYTREDQRSKSMAVIGAVIGAS 144
Query: 171 LVISPALGAYLMDLYGES--LXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISW 228
V++ LG ++ G S F + AVP K R + P W
Sbjct: 145 FVVAVMLGPWIAGFGGLSGLFWFTSALALAGLVITFWLPAVPSLQVHKERQ--FRPADLW 202
Query: 229 EQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAI 288
+ V +R V +L + +FL ++ + + V L + GF + A
Sbjct: 203 D----------VLTDRNVTILSLGIFLLHMTMTALFVALPVVL-VARGFASDGLGQIYAP 251
Query: 289 VGVLS-IGVQVILGFLMKSLGAKH--TIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAAL 345
V +LS IG+ ++ + L + G++ L L+W W A +L
Sbjct: 252 VMILSFIGMAPLMMISERRLAQVQFLRLAAGIVIGALLLLWQ---VPQWAASAVALLIFF 308
Query: 346 GSITY--PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ + + +S +RA +G G+ + + G A+ G++F
Sbjct: 309 VGFNFMEATLPSLLSRKARAQVRGTSMGVFSTAQFTGAAAGGAVGGLLF 357
>UniRef50_Q54IT2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 464
Score = 63.3 bits (147), Expect = 1e-08
Identities = 64/327 (19%), Positives = 141/327 (43%), Gaps = 21/327 (6%)
Query: 86 FLSAPLIGALSDVWGRKFFLLVTVFFTCAPIP--LMTINT---WWFFAMISISGVFAVTF 140
FL PL+G LSD +GRK + + + + + ++T+ T ++F+ + +G+
Sbjct: 99 FLFGPLLGNLSDKYGRKPIMYIGIGSSILDVVACIITVKTNCLYFFYVSHTFAGISNAAA 158
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
+ +F+++ D++ E + Y L+ A+ ++ P + L L S
Sbjct: 159 AAIFSFLKDLSEEDQLPLLYSLLGASIGIGVITGPLIFIGLSSLSLSSSSSSYIILLVAG 218
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQA-----DPFAALRKVGAERTVL--MLCVAV 253
+ +++ L E I+ + +PF ++ + + + ++ + V
Sbjct: 219 GLMILCISIIPFLKESTENAKLEKKINTNNSNNQTLNPFKLIKNLFSNSPFISFVILIYV 278
Query: 254 FLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSI--GVQVILGFLMKSLGAKH 311
+S+ E S F Y +L+ +G + +++ GV I GV +I+ L+K +
Sbjct: 279 LMSFSSEDVNTSYYF-YSELMYNWGSKENGLYLGSQGVFIIIWGV-LIIPILLKYFSPRK 336
Query: 312 TIMVGL---LFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGV 368
T+ +G+ + + L++ G+ W++ +A L A G+ I + VS + + QG
Sbjct: 337 TVSIGINVGIIAHISLVFSGYSKYLWILGSA--LNANGTNNLSLIQSIVSNSIPYNLQGT 394
Query: 369 VQGMVTGVRGLCNGLGPAMFGVIFYLF 395
+ + + L +F I+ F
Sbjct: 395 IITGTQAIGSMATFLASLIFENIYSYF 421
>UniRef50_Q8TUA4 Cluster: Class H tetracycline resistance efflux
protein; n=7; cellular organisms|Rep: Class H
tetracycline resistance efflux protein - Methanosarcina
acetivorans
Length = 450
Score = 63.3 bits (147), Expect = 1e-08
Identities = 87/396 (21%), Positives = 158/396 (39%), Gaps = 39/396 (9%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGAL 95
S+ L V F+ + ++ +P + L + F+ GL + + AP++G
Sbjct: 25 SLLPLLTVNFIGTLGFSIV-LPFLVFLVNRLGGNAFIY-GLASSMYPAFQLIGAPILGRW 82
Query: 96 SDVWGRKFFLLVT---------VFFTCAPIPLMTI--------NTWWF-------FAMIS 131
SD++GRK LL + +F +P++T+ T+ F F +
Sbjct: 83 SDIYGRKKILLFSQVGTLLSWIIFLGALFLPVVTLFQVDSEVLGTFAFTLPLAALFFARA 142
Query: 132 ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL-MDLYGESLX 190
G+ S+ AY+AD+T E +R+R +G +S + ++ PAL L + YGE+
Sbjct: 143 FDGLTGGNVSVANAYLADITEEKDRNRNFGKMSISSNLGFIVGPALAGLLSITAYGEAAP 202
Query: 191 XXXXXXXXXXXXFFIMVAVPE----SLPEKVRPTGWGPVISWE-------QADPFAALRK 239
I+ +PE SL V V +E + + R+
Sbjct: 203 VIGAVVISLIGTLLIIFYIPENKECSLEGPVEAKNIRKVFGYEIKECRTVRETGKPSFRE 262
Query: 240 VGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-V 298
V + + FL +L Y+ ++ + +G+ ++ ++ I+ L I VQ
Sbjct: 263 VFKLPNIPYMLGLYFLIFLGFNIFYTAFPLHAIAALDWGIAEMGVYFTILSGLLIIVQGS 322
Query: 299 ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVS 358
IL L K I+ G L + G+ A G A + +P+ + +S
Sbjct: 323 ILPRLSKRYSDASLIIFGSLMLGTNFLLLIPGNLFLTYLATGFFAMGDGLMWPSFLSLLS 382
Query: 359 VNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
+ + QG VQG GL + G + G+++ L
Sbjct: 383 KIAGKNYQGTVQGFAGSFGGLASITGLILGGLLYEL 418
>UniRef50_A6Q5H8 Cluster: Multidrug-efflux transporter, MFS family;
n=2; unclassified Epsilonproteobacteria|Rep:
Multidrug-efflux transporter, MFS family - Nitratiruptor
sp. (strain SB155-2)
Length = 444
Score = 62.9 bits (146), Expect = 2e-08
Identities = 80/365 (21%), Positives = 148/365 (40%), Gaps = 29/365 (7%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+++ L FF + + ++S T + G+ +G L G LSD GR
Sbjct: 13 LIVALRFFGL-FIVLAVLSQYALQLKGGTAFLAGVAVGGYAFTQALLQVPFGVLSDKIGR 71
Query: 102 KFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAERSRA 159
K +L+ + A + + + ++ + G A+ S+V A +AD E ER+ A
Sbjct: 72 KKTILIGLLLFAAGSVICAVADNIYVLLLGRFLQGSGAIG-SVVTAMIADYVREDERAHA 130
Query: 160 ---YGLVSA-TFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE 215
G+V A +FAA+++I P +G LY + AVPE
Sbjct: 131 MAVMGMVIAMSFAAAMIIGPIIGG----LYSVKALFWLTAILAILALGILFTAVPEP--- 183
Query: 216 KVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVM 275
P I ++ A +++V ++ ++ + + A + I + +K
Sbjct: 184 --------PKIVHHYSEEEAKIKEVFKDKDLVRMYITFLFHSSTMAIAFFIIPILMKQKF 235
Query: 276 GFG---VVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSR 332
G G +V + I G+LS+G + G K K +V +LF + GF S
Sbjct: 236 GLGPEHYWKVYLPAVIFGILSMGPAAVFG--EKYHKGKEVFIVSILFIAVSFALMGFSSS 293
Query: 333 TWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ V +G ++ P + ++VS +R ++G G+ + LG A+ G++
Sbjct: 294 FLLFTIGAVFFFIGFNMFEPLLQSFVSKFARVHQKGAALGVANTFAYIGIFLGGAIGGLL 353
Query: 392 FYLFH 396
+ H
Sbjct: 354 YQYGH 358
>UniRef50_Q54JQ8 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 640
Score = 62.5 bits (145), Expect = 2e-08
Identities = 31/115 (26%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Query: 73 MNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMI 130
++G+++G+ F S +G SD +GRK FL++++F T L + N W+ +
Sbjct: 216 VSGILVGVYSFARFGSGFYLGHFSDKYGRKPFLVMSLFVTGIGTVLFALMPNVWFALGLR 275
Query: 131 SISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLY 185
I G+F+ T ++ A +AD+ + R+ + + T+A S IS ++G +++ ++
Sbjct: 276 MIEGLFSNTTALCQATLADMVDKKNRAAVFAYLGGTYALSRCISSSMGGFIVKIF 330
Score = 35.5 bits (78), Expect = 3.1
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 15/122 (12%)
Query: 277 FGVV-QVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWM 335
FG + Q+ +F + G + Q +G ++ S+G LF + + W G +
Sbjct: 475 FGFLWQILLFKKVSGRFGLKRQYTVGMILLSIGMA-------LFPLSYVAWNIQGYP--L 525
Query: 336 MWAA-GVLAALGSITY----PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
+W G++ + S+ + P + V+ S + QG+ QG + + GPA+ G
Sbjct: 526 VWVTIGIVVPIISVGFMSGLPIVQGMVANCSNPEIQGLTQGSTQSINSMLRSFGPAISGA 585
Query: 391 IF 392
IF
Sbjct: 586 IF 587
>UniRef50_Q8TZJ0 Cluster: Sucrose transport protein; n=3;
Thermococcaceae|Rep: Sucrose transport protein -
Pyrococcus furiosus
Length = 442
Score = 62.5 bits (145), Expect = 2e-08
Identities = 73/309 (23%), Positives = 128/309 (41%), Gaps = 28/309 (9%)
Query: 43 VIFLEFFAWGLLTMPII-SVLNATFP---DHTFLMN----GLIMGIKGILSFLSAPLIGA 94
+IFL +G + II S+ NA P TF MN G IM I + + + P +GA
Sbjct: 9 MIFL--LGFGFFGISIIWSLYNAYIPIFLQETFKMNRTITGFIMTIDNLFAVILLPFLGA 66
Query: 95 LSD-----VWGRKFFLLV-----TVFFTCAPIPLMTINTWWFFAMISISGVFAVTF-SIV 143
LSD + RK ++L+ + F P+ N F I F F S V
Sbjct: 67 LSDMTRTRIGRRKPYILLGAPSAAIMFALIPVARKYENLALFMGTIIFMNFFMALFRSPV 126
Query: 144 FAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXXXX 202
A++ D+T +RS+A G+++ +++ G +L D+ Y
Sbjct: 127 IAFMPDITPSEKRSQANGIINFMGGLGALLAYFGGKFLYDINYALPFYVGAIVMLLANLL 186
Query: 203 FFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRK------VGAERTVLMLCVAVFLS 256
I+V PE K + ++S F L++ + E+++L + +A+F
Sbjct: 187 VVILVPEPEEYCIKGQKLEIRKILSETAHKSFGELKENLKDVFLSKEKSLLAILLAIFFW 246
Query: 257 YLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVG 316
++ + Y K +G A + +V + + + GFL +G + TI G
Sbjct: 247 FIAFNSLETFFTSYAKYHLGISESTGAFIMGVVSLSFMIFAIPAGFLGGKIGRRKTITAG 306
Query: 317 LLFEMLQLM 325
L+ ++ L+
Sbjct: 307 LVLIVIVLI 315
>UniRef50_Q9RN46 Cluster: 12-TMS multidrug efflux protein homolog;
n=4; Proteobacteria|Rep: 12-TMS multidrug efflux protein
homolog - Salmonella typhi
Length = 413
Score = 62.1 bits (144), Expect = 3e-08
Identities = 70/328 (21%), Positives = 141/328 (42%), Gaps = 18/328 (5%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMI- 130
L+ G+I+ + F +APLIG LSD GRK L+VT+ + L+ F ++
Sbjct: 55 LIIGIIIATEAFSQFCAAPLIGHLSDRVGRKRILIVTLAIAAISLLLLANAQCILFILLA 114
Query: 131 -SISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
++ G+ A S AY+AD T R +A G+++ ++ + +L + SL
Sbjct: 115 RTLFGISAGNLSAAAAYIADCTHVRNRRQAIGILTGCIGLGGIVGAGVSGWLSRI---SL 171
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLML 249
++ P T + S+ A+ K+ R ++++
Sbjct: 172 GAPIYAAFILVLGAALVAIWGLKDPSTTSRT-TDKIASFSA----RAILKMPVLRVLIIV 226
Query: 250 CVAVFLSYLPEAGQYSCIF--VYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKS 306
+ F +Y + Q ++ + FG ++ + GV++I VQ+ +LG++ +
Sbjct: 227 MLCHFFAYGMYSSQLPVFLSDTFIWNGLPFGPKALSYLLMADGVINIFVQLFLLGWVSQY 286
Query: 307 LGAKHTIMVGLLFEMLQLMWYGFGSRTW---MMWAAGVLAALGSITYPAISAYVSVNSRA 363
+ I+ L+F +L + G T +++A ++ ++ P A +SV+
Sbjct: 287 FSERKLII--LIFALLCTGFLTAGIATTIPVLIFAIVCISIADALAKPTYLAALSVHVSP 344
Query: 364 DRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
RQG+V G + + + + P + G +
Sbjct: 345 ARQGIVIGTAQALIAIADFISPVLGGFV 372
Score = 37.1 bits (82), Expect = 1.0
Identities = 44/184 (23%), Positives = 77/184 (41%), Gaps = 21/184 (11%)
Query: 19 KTVMKDGIMTMSGIGEPSVFHALVVIFL-EFFAWGLLTMPIISVLNATFPDHTFLMNGLI 77
+T K + I + V L+++ L FFA+G+ + + F TF+ NGL
Sbjct: 201 RTTDKIASFSARAILKMPVLRVLIIVMLCHFFAYGMYSSQL-----PVFLSDTFIWNGLP 255
Query: 78 MGIK---------GILS-FLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTW--- 124
G K G+++ F+ L+G +S + + +++ C I T
Sbjct: 256 FGPKALSYLLMADGVINIFVQLFLLGWVSQYFSERKLIILIFALLCTGFLTAGIATTIPV 315
Query: 125 WFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD- 183
FA++ IS A+ A ++ + A + G A A + ISP LG +++
Sbjct: 316 LIFAIVCISIADALAKPTYLAALSVHVSPARQGIVIGTAQALIAIADFISPVLGGFVLGY 375
Query: 184 -LYG 186
LYG
Sbjct: 376 ALYG 379
>UniRef50_Q6ET95 Cluster: Tetracycline transporter protein-like;
n=4; Magnoliophyta|Rep: Tetracycline transporter
protein-like - Oryza sativa subsp. japonica (Rice)
Length = 211
Score = 62.1 bits (144), Expect = 3e-08
Identities = 34/139 (24%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Query: 251 VAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGA 309
+ F L E G + + YLK G+ + A + I G + Q+ ++ L + +G
Sbjct: 16 IVTFFYSLGEHGLQTALLYYLKAQFGYSKDEFANLLLIAGAAGMLSQLTVMPVLARFVGE 75
Query: 310 KHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVV 369
+++GLL + YG W+ + + V L + +P+I VS + ++ QG+
Sbjct: 76 DILLIIGLLGGCTHVFLYGIAWSYWVPYLSAVFIILSAFVHPSIRTNVSKSVGSNEQGIA 135
Query: 370 QGMVTGVRGLCNGLGPAMF 388
QG ++G+ + L P +F
Sbjct: 136 QGCISGISSFASILAPLIF 154
>UniRef50_Q3DYD2 Cluster: Tetracycline resistance protein; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Tetracycline
resistance protein - Chloroflexus aurantiacus J-10-fl
Length = 256
Score = 61.7 bits (143), Expect = 4e-08
Identities = 54/215 (25%), Positives = 92/215 (42%), Gaps = 8/215 (3%)
Query: 181 LMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKV 240
++ YG +L + +A+PE+LP R PV +PFAA V
Sbjct: 1 MLSQYGLALPPAVAATIAFLNALWATIALPETLPPNRRRIQ--PV---RLTNPFAAAVTV 55
Query: 241 GAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VI 299
+ L AV + + AG + + + G+G Q A+ VG+ ++ Q V+
Sbjct: 56 LTLPQIRPLLGAVVILNIAFAGLQNNVAYFTMTRFGWGPEQNAVLFVFVGLCAVVTQGVL 115
Query: 300 LGFLMKSLGAKHTIMVGLLFEMLQLMWYGF-GSRTWMMWAAGVLAALG-SITYPAISAYV 357
L L LG +H GL L G + +W ++ + A G + PA+++ +
Sbjct: 116 LRILQPLLGERHLAGGGLGLMALGFALVGLVHNESWRLFPIAAMFATGMGLAVPALTSLI 175
Query: 358 SVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
S+ + RQG + G + + + +GP FG IF
Sbjct: 176 SLRAGDRRQGAILGGMQTLISIALVIGPLSFGFIF 210
>UniRef50_Q14J11 Cluster: Multidrug transporter; n=11; Francisella
tularensis|Rep: Multidrug transporter - Francisella
tularensis subsp. tularensis (strain FSC 198)
Length = 412
Score = 61.7 bits (143), Expect = 4e-08
Identities = 70/315 (22%), Positives = 129/315 (40%), Gaps = 23/315 (7%)
Query: 87 LSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTW-----WFFAMISISGVFAVTFS 141
+ P+IG LSD +GRK L+V + TC L + F A + G+ F
Sbjct: 72 IGCPIIGELSDKYGRKIILIVALSTTCVSYILSAYAIYSHHYLLFVASRFVCGLAGGAFE 131
Query: 142 IVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXX 200
I A V D++TE ++S+ G ++ + V+ P + +++ + +L
Sbjct: 132 IAQAAVIDISTEEDKSKNLGYITMAASLGFVVGPIVTSFVSVMNISHTLPFIFAAVLSLL 191
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
FI++ + + LP+ P + + A + + + +++ V ++ V L
Sbjct: 192 NIIFIVIIMTKDLPK-------NPGLVIQLATIYKTISFLLSDKRVRLIGVVYLLVQCAW 244
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVG----VLSIGVQ-VILGFLMKSLG-AKHTIM 314
I ++L L + V Q F A++G + SI +Q VI L + + ++
Sbjct: 245 GFYGQGIALFLNLTYSYTVSQTGAFYALMGLSTALASIIIQPVIFARLSNQVAFVRAAVV 304
Query: 315 VGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVT 374
G+ F + ++ W++ VL++ I Y A+ A +S QG G
Sbjct: 305 CGIGFIFVAILTNQIAQ--WLLTI--VLSSSQLICYTALLAMISGAVTDKEQGKAMGAAG 360
Query: 375 GVRGLCNGLGPAMFG 389
GL L M G
Sbjct: 361 AGFGLAWFLNDIMMG 375
>UniRef50_A3I8X0 Cluster: Putative uncharacterized protein; n=2;
Bacillus|Rep: Putative uncharacterized protein -
Bacillus sp. B14905
Length = 389
Score = 61.7 bits (143), Expect = 4e-08
Identities = 63/330 (19%), Positives = 138/330 (41%), Gaps = 16/330 (4%)
Query: 36 SVFHALVVIFLEFFAW----GLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPL 91
++FH LV I L + + MP +++ + + L GL +GI ++S +
Sbjct: 5 NLFHPLVWIILGGTVFTRIASFMAMPFLAIYLHNEIEASPLQIGLTIGIAPLISTVGGFF 64
Query: 92 IGALSDVWGRKFFLLVTVF-FTCAPIPLMTINTWWFFAMI-SISGVFAVTFS-IVFAYVA 148
G L+D +GRK +L+T+ ++ T++T W F + +++G+ F A +
Sbjct: 65 GGYLTDRFGRKSVILLTIIVWSLVFFGFATVHTVWLFILFNALNGLCRSFFEPSTQALMI 124
Query: 149 DVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVA 208
D T +R R + L + VI P +G Y+ L S+ F+
Sbjct: 125 DFTPSDKRKRLFSLRYTAINIAAVIGPIIGVYISQLASPSIPFMLTGIMYIIYAIFLFFV 184
Query: 209 VPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
+ ++ + V+ + F L R +L L + + S +
Sbjct: 185 LNRYQMQQQK-----AVMQTKILHTFTILL---TNRVLLSFIFGAILINIGYSQFDSTLP 236
Query: 269 VYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+++L + G ++ I++ + + +Q+ + + + + T+++G+LF + L +G
Sbjct: 237 QFIELTVENGTKLYSLLISLNAAVVLLLQLPISIVSERFSSSATLLIGILFFAIGLFMFG 296
Query: 329 FGSRTWMMWAAGVLAALGSI-TYPAISAYV 357
+ A ++ +G I +P ++ +
Sbjct: 297 LSDNYTLYIIAMIIFTIGEIFAFPTMNVMI 326
>UniRef50_A0Z2L4 Cluster: Multidrug-efflux transporter; n=1; marine
gamma proteobacterium HTCC2080|Rep: Multidrug-efflux
transporter - marine gamma proteobacterium HTCC2080
Length = 405
Score = 61.7 bits (143), Expect = 4e-08
Identities = 37/141 (26%), Positives = 70/141 (49%), Gaps = 4/141 (2%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
VI ++ +G+L +PI+ ++ + ++ I + + ++ P G LSD GRK
Sbjct: 17 VIVVDLIGFGIL-IPILPFMSPALGGDEMDV-AFVIAIYSLCAGIAGPFWGGLSDRIGRK 74
Query: 103 FFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAY 160
L+V +F ++ + + W +A ++ GV A + + A +ADV+ R++A
Sbjct: 75 QVLMVCLFGGALSYGMIGVASELWMLYAARAVGGVMAGSLPVASALMADVSAPHRRAKAM 134
Query: 161 GLVSATFAASLVISPALGAYL 181
GLV F L++ P +G L
Sbjct: 135 GLVGTAFGLGLILGPVIGGVL 155
Score = 47.6 bits (108), Expect = 7e-04
Identities = 35/125 (28%), Positives = 55/125 (44%)
Query: 267 IFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
I ++ +G + VA IAI + + G L +G K +MV L L
Sbjct: 31 ILPFMSPALGGDEMDVAFVIAIYSLCAGIAGPFWGGLSDRIGRKQVLMVCLFGGALSYGM 90
Query: 327 YGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPA 386
G S WM++AA + + + + P SA ++ S R+ G+V GL LGP
Sbjct: 91 IGVASELWMLYAARAVGGVMAGSLPVASALMADVSAPHRRAKAMGLVGTAFGLGLILGPV 150
Query: 387 MFGVI 391
+ GV+
Sbjct: 151 IGGVL 155
>UniRef50_Q64DZ9 Cluster: Permeases of the major facilitator
superfamily; n=3; environmental samples|Rep: Permeases
of the major facilitator superfamily - uncultured
archaeon GZfos17A3
Length = 418
Score = 61.3 bits (142), Expect = 5e-08
Identities = 84/367 (22%), Positives = 152/367 (41%), Gaps = 22/367 (5%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F ++++F F + P+ F +H L+ GLI I + IG LS
Sbjct: 18 LFSIVILLFCSFIGAVITVHPLYL---EQFVEHPALV-GLIAAISSFAGLTFSLPIGTLS 73
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTINTWWF-FAMISIS-GVFAVTFSIV-FAYVADVTTE 153
D GRK L+V+ F + INT + ++ I+ GVF +V A++ D+ +
Sbjct: 74 DREGRKPMLIVSFGFVSVVLLAFFINTRLYPLILLQITFGVFMAPIWVVGEAFIKDI-SP 132
Query: 154 AERSRAYGLVSATFA-ASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
ER + TFA A L+I +G +L + +G I++ VP
Sbjct: 133 TERRGEFRSFFGTFANAGLLIGALIGGFLAEAFG---------IRSPYLFAAILLVVPLI 183
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
L ++ + D L++ +R + +L + Y A ++ IF L
Sbjct: 184 LVFGMKDGHSNTNKNQAVMDFLPVLKEFLQQRELKLLALCTVSLYFWYAARW--IFGPLF 241
Query: 273 L-VMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGS 331
L +G+ + +++A+ + + Q+ +G L +G + +G L + L+ GF S
Sbjct: 242 LHDLGYSPYIIGVWLAVSVLPFLLFQIPIGKLSDKIGKSRIMYLGFLISAVSLIPLGFMS 301
Query: 332 RTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGV 390
+ A + ++G + P I A V+ +R G G+ + L LGP +
Sbjct: 302 SISSLLATIFIVSIGTAFVEPLIEARVTDIVPKERYGAYSGIFEFTKTLGLMLGPVGSAI 361
Query: 391 IFYLFHV 397
Y F +
Sbjct: 362 FVYSFGI 368
>UniRef50_Q7NNZ0 Cluster: Glr0268 protein; n=1; Gloeobacter
violaceus|Rep: Glr0268 protein - Gloeobacter violaceus
Length = 567
Score = 60.5 bits (140), Expect = 1e-07
Identities = 59/226 (26%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLV--TVF----FTCAPIPLMTINTWWFFAMISISGVF 136
++S S P++G LSD++GRK LL+ +F F C P M + F I G
Sbjct: 88 LVSTTSLPILGKLSDLYGRKNILLIGIAIFLLGSFLCGLAPSMLMLV--VFRGIQGLGAG 145
Query: 137 AVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXX 196
A+T S+ AD+ AER++ G+++A FA S ++ P LG L D G
Sbjct: 146 AIT-SVALTIPADLYVPAERAQLQGIIAAVFALSSIVGPLLGGVLTDTLGWHWIFFINLP 204
Query: 197 XXXXXXFFIMVAVPESLPEKVRPTG-WGPVISWEQADPFAALRKVGAERTVLMLCVAVFL 255
FI+ +P R WG V+ P L + E+ + L
Sbjct: 205 FGLLALAFIVAFMPRLNSGLTRSIDYWGAVLLMLTVVPL--LVALSLEKEKYAWDSPLVL 262
Query: 256 SYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILG 301
L A +FV+ +L ++ +++F + L + V++G
Sbjct: 263 GLLAAAAVSFGLFVFAELRAKEPILPLSLFRIPIFSLICAMSVMVG 308
Score = 34.3 bits (75), Expect = 7.2
Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 5/153 (3%)
Query: 243 ERTVLMLCVAVFLS-YLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-IL 300
ERT ++ AV ++ +L Q + K+V G + + + + +L + IL
Sbjct: 38 ERTKRLVMGAVLIALFLTSLDQTVVVAALPKIVADLGDLDLLAWTSASYLLVSTTSLPIL 97
Query: 301 GFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS--ITYPAISAYVS 358
G L G K+ +++G+ +L G M+ + LG+ IT A++
Sbjct: 98 GKLSDLYGRKNILLIGIAIFLLGSFLCGLAPSMLMLVVFRGIQGLGAGAITSVALTIPAD 157
Query: 359 VNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ A+R +QG++ V L + +GP + GV+
Sbjct: 158 LYVPAER-AQLQGIIAAVFALSSIVGPLLGGVL 189
>UniRef50_A3ZND9 Cluster: Multidrug resistance protein; n=1;
Blastopirellula marina DSM 3645|Rep: Multidrug
resistance protein - Blastopirellula marina DSM 3645
Length = 433
Score = 60.5 bits (140), Expect = 1e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFP-DHTFLMNGLIMGIKGILSFLSAPLIGALSDVWG 100
+ +F++ +G++ +P++ + A F D + GL+M + FL APL G LSD G
Sbjct: 22 LTVFIDLLGFGIV-LPLLPIYAAQFGVDEHGIELGLLMASFSAMQFLFAPLWGLLSDRIG 80
Query: 101 RKFFLLV-----TVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAE 155
R+ +++ +F+ I W F +G+ T S AY+AD T+
Sbjct: 81 RRPVIMIGLSGSVIFYAIFGIATEWQCIWLLFVARIGAGIAGATISTAQAYIADTTSLEN 140
Query: 156 RSRAYGLVSATFAASLVISPALG 178
RS+ L+ F P LG
Sbjct: 141 RSKGMALIGMAFGLGFTFGPLLG 163
>UniRef50_Q14728 Cluster: Tetracycline transporter-like protein;
n=23; Euteleostomi|Rep: Tetracycline transporter-like
protein - Homo sapiens (Human)
Length = 455
Score = 60.5 bits (140), Expect = 1e-07
Identities = 77/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 69 HTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWW--F 126
++ L GLI +L FL APL GA SD GR+ +L+ + + + + F
Sbjct: 84 NSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAF 143
Query: 127 FAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
A I G+ S+ A VAD+ + RS+ ++ F+ + P LGA L
Sbjct: 144 LASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASL----P 199
Query: 187 ESLXXXXXXXXXXXXXFFIMVAVPESLP-EKVRPT-GWGPVISWEQADPFAALRKVGAER 244
+ FI +PE+LP EK P+ G + + P A LR R
Sbjct: 200 LEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFSAVAR 259
Query: 245 -----------TVLMLCVAVFLSYLPEAG-QYSCIFVYLKLVMGFGVVQVAIFIAIVGVL 292
++ L + FL +G +Y+ F+ + F +Q ++G+
Sbjct: 260 GQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQ-FSSLQQGKMFFLIGLT 318
Query: 293 SIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVL--AALGSITY 350
+Q + G + LL + + G+G R+ + G+L + ++
Sbjct: 319 MATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWG-RSLPVLGLGLLLYSFAAAVVV 377
Query: 351 PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
P +S+ V+ ++G V G + + L GP + +++L
Sbjct: 378 PCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYWL 421
>UniRef50_Q58955 Cluster: Uncharacterized MFS-type transporter
MJ1560; n=2; Methanococcales|Rep: Uncharacterized
MFS-type transporter MJ1560 - Methanococcus jannaschii
Length = 386
Score = 60.5 bits (140), Expect = 1e-07
Identities = 75/362 (20%), Positives = 146/362 (40%), Gaps = 14/362 (3%)
Query: 34 EPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIG 93
E +VF + F G + PI+++ T T L GLI G + ++ +G
Sbjct: 5 EKNVFVIWITTFTTMLGVGFIA-PIMAIYAQTL-GATNLEIGLIFGSFALARTVAQIPVG 62
Query: 94 ALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWWFFAMISI-SGVF-AVTFSIVFAYVADV 150
LSD++G+KFF++ T F+ + + ++T F ++ I +G+F A + +Y+A +
Sbjct: 63 VLSDIYGKKFFIVCGTFFYGVSTLMYNFVSTVLGFLIVRIFTGIFSAFVTPVAGSYIAAI 122
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVP 210
+ G+ ++ I P +G L D+YG + + +
Sbjct: 123 APKTRLGEYMGIFNSAITLGFGIGPFIGGILADMYGIKMPFYFCGFLGILAAIISYMKLE 182
Query: 211 ESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVY 270
+ + K + IS + F R + + + V + AG Y+ + +Y
Sbjct: 183 DIVFNKNKEKIDVKKISTLFSFEFLKNRNFSSSFIINVSNVMI------NAGIYAYLALY 236
Query: 271 LKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFG 330
+ + QV IA+ +L +Q G L LG I++G+ +
Sbjct: 237 -AINYNITISQVGFMIALTNILMALLQRSFGKLYDKLG-NIMIIIGIFIISFGMYLLSTS 294
Query: 331 SRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFG 389
+ + A+ + A+G SI+ A ++ + R+G G+ T + +G FG
Sbjct: 295 TTFLTILASLTIIAVGSSISSTATTSLAVKDIPTHRKGEAMGLFTTSINIGMFIGAVSFG 354
Query: 390 VI 391
+
Sbjct: 355 FL 356
Score = 37.1 bits (82), Expect = 1.0
Identities = 29/158 (18%), Positives = 61/158 (38%), Gaps = 2/158 (1%)
Query: 243 ERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGF 302
E+ V ++ + F + L G + I +G +++ + + Q+ +G
Sbjct: 5 EKNVFVIWITTFTTMLG-VGFIAPIMAIYAQTLGATNLEIGLIFGSFALARTVAQIPVGV 63
Query: 303 LMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVNS 361
L G K I+ G F + + Y F S + + S P +Y++ +
Sbjct: 64 LSDIYGKKFFIVCGTFFYGVSTLMYNFVSTVLGFLIVRIFTGIFSAFVTPVAGSYIAAIA 123
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDL 399
R G G+ L G+GP + G++ ++ + +
Sbjct: 124 PKTRLGEYMGIFNSAITLGFGIGPFIGGILADMYGIKM 161
>UniRef50_Q86B08 Cluster: Similar to Leptospira interrogans serovar
lai str. 56601. Tetracycline resistance protein, class
A; n=2; Dictyostelium discoideum|Rep: Similar to
Leptospira interrogans serovar lai str. 56601.
Tetracycline resistance protein, class A - Dictyostelium
discoideum (Slime mold)
Length = 471
Score = 60.1 bits (139), Expect = 1e-07
Identities = 64/310 (20%), Positives = 129/310 (41%), Gaps = 12/310 (3%)
Query: 79 GIKGILSFLSAPLIGALSDVWGRK--FFL-LVTVFFTCAP--IPLMTINTWWFFAMISIS 133
G ++ FL PL+G +SD +GRK F+L ++TV F + + T N + F+ +I
Sbjct: 98 GFPFLVMFLFGPLVGYISDRYGRKSNFYLSVLTVMFVIMSCFVSMETNNIYCFYVFHTIG 157
Query: 134 GVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL-MDLYGESLXXX 192
G++ V+ S+VF+++ D++ E + + L + I + A++ D +
Sbjct: 158 GLYNVSNSVVFSFIYDISDEKDIPVLFTLCGLSMGLGTTIGSLIYAFVPTDKVPYMMLYI 217
Query: 193 XXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVA 252
+ + + S+E +PF+ ++ + + +
Sbjct: 218 SSGFALVSLILVPFLIETIHISRENNKNKTFVKKSFENPNPFSTIKSLFTNNGFISWTIL 277
Query: 253 VFLSYLPEAGQ--YSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV-ILGFLMKSLGA 309
+F S + GQ +S + Y L+ + + +F VG +I V I+ +K L
Sbjct: 278 LFFS-IQYTGQDIWSTFYYYSYLMYNWNQKTIGLFTLGVGGATILYSVLIVPLFLKVLSE 336
Query: 310 KHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVV 369
K I +G + + ++ G A + SI + SV S++ Q V
Sbjct: 337 KKVITIGFFITFCAHVMLSSSKFSQYLFIFG--AIVSSIVPCVSNLLCSVISKSTPQEVQ 394
Query: 370 QGMVTGVRGL 379
++TG++ +
Sbjct: 395 GSVLTGLQSV 404
>UniRef50_A1S0L4 Cluster: Major facilitator superfamily MFS_1; n=2;
cellular organisms|Rep: Major facilitator superfamily
MFS_1 - Thermofilum pendens (strain Hrk 5)
Length = 421
Score = 60.1 bits (139), Expect = 1e-07
Identities = 71/305 (23%), Positives = 135/305 (44%), Gaps = 24/305 (7%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWG-----RKFFLLV---TVFFTCAPIPLMTINTWWF 126
G IM I I + + P IG LSDV RK ++++ T A IPL+ + +
Sbjct: 45 GFIMTIDNIFAVVLLPYIGVLSDVTRTRIGRRKPYIILGAPPAALTFALIPLLRGDFYAM 104
Query: 127 FAMISISGVFAVTF-SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLY 185
A+I + F S V A++ D+T +RS+A G+++ +++ +GA L ++
Sbjct: 105 LAVIVVMNFSMALFRSPVIAFMPDITPSEKRSQANGIINFMGGVGSLLAFFVGAKLYEM- 163
Query: 186 GESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPF--------AAL 237
S +++ V E PE+ + G + + F A L
Sbjct: 164 NPSYPFVAAAVTMLLASLLVVLLVDE--PEEFKARGGSVRLGELLRESFRKSFSELSANL 221
Query: 238 RK--VGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIG 295
R+ +G ++++L + ++FL ++ + Y K +G G ++ + V + +
Sbjct: 222 REAFLGEDKSLLFMLASIFLWFIGYNAIETFFTSYAKWYLGIGEAAGSLILGFVALGFLV 281
Query: 296 VQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISA 355
+ GF+ LG + T+ +GL ++ L+ F + T + A V+ LG+I + A
Sbjct: 282 FSLPAGFIGARLGRRKTMTLGLAL-LVVLLGLAFYASTAVKTGA-VIYVLGAIFFFGGFA 339
Query: 356 YVSVN 360
+ VN
Sbjct: 340 WALVN 344
>UniRef50_Q649G3 Cluster: Multidrug efflux transporter; n=1;
uncultured archaeon GZfos35A2|Rep: Multidrug efflux
transporter - uncultured archaeon GZfos35A2
Length = 243
Score = 59.7 bits (138), Expect = 2e-07
Identities = 57/231 (24%), Positives = 100/231 (43%), Gaps = 21/231 (9%)
Query: 41 LVVIFLEFFAWGLLTMPIISVLNATFPDH---TFLMNGLIMGIKGILSFLSAPLIGALSD 97
L ++ FA +L + IIS L T + T + G+I I + P++G LSD
Sbjct: 10 LFSLYFSIFA-AILGLSIISPLLPTIAEDLRVTGVWMGMIFSGYAISRAIIMPVMGGLSD 68
Query: 98 VWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFA-VTFSIVFAYVADVTTEA 154
+GRK F+ + + + + L+ N + A+ ++G+ A + + AY +V E
Sbjct: 69 KYGRKIFIASGLLLLAVISLLYLLAHNVYTLTAVRLLNGLAAGMIIPVAMAYAGEVAQEG 128
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP 214
+ RA G+++ F + + P +G ++ S F ++ V LP
Sbjct: 129 KEGRAMGIITMIFYLGIAVGPFIGG----IFWHSFGATSVFYVMSGISAFALLLVLHFLP 184
Query: 215 EKVRPTGWGPVISWEQADPFAALRKVGAERTVLML------CVAVFLSYLP 259
E +P E+ +PF L K A + VL++ V LS+LP
Sbjct: 185 EIKKP----KASKTEEHEPFKNLIKRDAVKIVLIIGFISAFRTGVLLSFLP 231
Score = 33.9 bits (74), Expect = 9.5
Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 296 VQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAIS 354
+ ++G L G K I GLL + + Y + + A +L L + + P
Sbjct: 59 IMPVMGGLSDKYGRKIFIASGLLLLAVISLLYLLAHNVYTLTAVRLLNGLAAGMIIPVAM 118
Query: 355 AYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
AY ++ ++G G++T + L +GP + G+ ++ F
Sbjct: 119 AYAGEVAQEGKEGRAMGIITMIFYLGIAVGPFIGGIFWHSF 159
>UniRef50_A3XY06 Cluster: Putative mfs transporter; n=1; Vibrio sp.
MED222|Rep: Putative mfs transporter - Vibrio sp. MED222
Length = 400
Score = 59.3 bits (137), Expect = 2e-07
Identities = 85/342 (24%), Positives = 139/342 (40%), Gaps = 33/342 (9%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTI------NTWWFF 127
GL++ + GI LSA G SD GRK LLV T+ + C+ I LMTI T +
Sbjct: 40 GLVVAMSGIAWLLSAKKWGETSDKKGRKPVLLVATLGYACSFI-LMTIWLDLSLKTTFHS 98
Query: 128 AMISISGVFAVTFSIVF---------AYVADVTTEAERSRAYGLVSATFAASLVISPALG 178
+I I + A TF +F A VAD+T+ ER A + A A LV PALG
Sbjct: 99 LIILIGMIVARTFVGLFLAAITPISTALVADITSPKERQSAMASIGAASAIGLVAGPALG 158
Query: 179 AYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALR 238
++ Y +L I + +PE+ + + ++Q F AL
Sbjct: 159 G-MLSQYSLTLPLYVLSVFPFIAWVTIKIRLPET--TIIHEPSENTLSFFDQRLRFPALA 215
Query: 239 KVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQV 298
V+ + + L S L G+V + I G+ ++G+
Sbjct: 216 MFACMFAVITAQIIIGFLILDRIRDTSEQAAQLS-----GIV-----LTITGI-TLGITQ 264
Query: 299 ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYV 357
MK+ + M+G + L ++ + A+G + +PAI A
Sbjct: 265 AFLAKMKNNVLLKSFMMGPIMACAGLGIVSVAHSATLLITGYIFMAIGLGLLFPAIQAIT 324
Query: 358 SVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVDL 399
+ + + QG G ++ ++GL + +GP + I Y ++ L
Sbjct: 325 ANSVDMNEQGAASGTISAIQGLSSIVGP-ITATILYQYNQSL 365
>UniRef50_A7RPG8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 420
Score = 59.3 bits (137), Expect = 2e-07
Identities = 38/109 (34%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTIN-TWWFFAMISIS 133
GLI + G + F S PL+G SDV GRK LLV++ T A L ++ + A+ I
Sbjct: 51 GLIGSVYGAIQFFSNPLVGKFSDVAGRKKVLLVSLLGTGAAYLLHGLSVSLIMLALTRIP 110
Query: 134 -GVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL 181
G+F + S+ A +AD+T A+R +G +A + V+ P +G +L
Sbjct: 111 IGLFKQSQSLCKACLADITAPAQRISVFGKFNAFSSLGFVVGPLIGGHL 159
>UniRef50_A7D0E0 Cluster: Major facilitator superfamily MFS_1; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Major
facilitator superfamily MFS_1 - Halorubrum lacusprofundi
ATCC 49239
Length = 453
Score = 59.3 bits (137), Expect = 2e-07
Identities = 87/394 (22%), Positives = 152/394 (38%), Gaps = 46/394 (11%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
V+F++ +G++ +PI+ +F + GL+ + FL+AP +G LSD GR+
Sbjct: 35 VVFIDLVGFGIV-IPILPFYVRSFGVSDAFI-GLLAASYSLAQFLAAPTLGRLSDRIGRR 92
Query: 103 FFLLVT--------VFFTCAPIPLMTINTW----WFFAMISISGVFAVTFSIVFAYVADV 150
LL + V F A T FA +++G + AYVAD+
Sbjct: 93 PVLLASLATAGVAWVTFGYAGESGARFGTAAALATLFASRTLAGAMGGNIAAAQAYVADI 152
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYL----MDLYGESL-------XXXXXXXXXX 199
T R+ A GLV A+FA V PA+G L + ++L
Sbjct: 153 TPRDRRAGALGLVGASFALGFVFGPAIGGLLAADAVVARADALLPAFVPATAYSLPSFAA 212
Query: 200 XXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLP 259
F+ V V E+ + T + R + T+ L VA F+ +
Sbjct: 213 AGMSFLAVGVGFVFLEEPKRTRPTEEVEGRHTTAIGQFRNALSSVTLRPLTVAYFVVAVA 272
Query: 260 EAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGAKHTIMVG-- 316
AG Y+ G+ A + VGVL ++ V++G L + + ++ + G
Sbjct: 273 FAGVQVMFIPYVADAFGYDATAAAFLLTYVGVLGAVNQGVLVGRLSRVVPSRTLVAAGSV 332
Query: 317 -LLFEMLQLMWYG----------FGSRTW-------MMWAAGVLAALGSITYPAISAYVS 358
L ++ + G G W ++ A L+ ++ +++ VS
Sbjct: 333 ILAGALVAIPATGLVDRAAGDVALGGPAWLTLPLVALLIALAALSLGNALVNVSLATLVS 392
Query: 359 VNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
++ QG G+ G L +GP + V++
Sbjct: 393 ASAGDAEQGAAFGVTQGASSLGRTVGPPLMAVLY 426
>UniRef50_Q2YHS5 Cluster: Putative uncharacterized protein; n=1;
Kluyvera ascorbata|Rep: Putative uncharacterized protein
- Kluyvera ascorbata
Length = 418
Score = 58.8 bits (136), Expect = 3e-07
Identities = 86/366 (23%), Positives = 154/366 (42%), Gaps = 25/366 (6%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F LV+ F F AW P I+V+ + + GL M ++S + G +S
Sbjct: 30 LFFTLVIRFSYFMAW-----PFIAVIMTQNYHMSPIAIGLAMTSSALISVVLGMYGGQIS 84
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTINTWW--FFAMISISGV-FAVTFSIVFAYVADVTTE 153
D GR+ LL+ F+ ++ T F + I GV FA V A ++D+ +
Sbjct: 85 DRLGRRVILLLGCGFSAVGYIILAQATGMALFICGLMIIGVCFAWVDPPVRALMSDLLGD 144
Query: 154 AERSRAYGLVSATFAASL--VISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
R RA L + ++ V P +G + L + ++++ VP
Sbjct: 145 -RRRRALALQMRYYLINVAAVFGPLVG-IVFGLTSQKGTFLITGLSYLPFFVYVLLFVPA 202
Query: 212 -SLPEKVRPTGWGPVISWEQADPFAALRKVG-AERTVLMLCVAVFLSYLPEAGQYSCIFV 269
L ++ + TG GP I + Q A K+ A +LC VF+ Y Q
Sbjct: 203 GKLLDEGQQTGSGPAIKFHQVIGVIARDKIYIAALLCSILCSVVFIHYEAVLPQ------ 256
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGV--QVILGFLMKSLGAKHTIMVGLLFEMLQLMWY 327
YL + G +++ I + ++ V I+ F+ + + +M G +F + QL ++
Sbjct: 257 YLLSLDGNAAIKLITLILVTNACTVLVFQTFIVRFMAQMTLPRRILMGGAVFFLAQLSFF 316
Query: 328 GFGSRTWMMW-AAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGP 385
S +W +A L ++G +I P ++ + + A+ +G G T + L +GP
Sbjct: 317 SIRSTDMGLWLSATCLFSMGEAILMPNLNILLDQLAPAEHRGAYLGAST-LSTLGIAVGP 375
Query: 386 AMFGVI 391
+ GV+
Sbjct: 376 LIGGVL 381
>UniRef50_A0NRK3 Cluster: Multidrug transporter, putative; n=1;
Stappia aggregata IAM 12614|Rep: Multidrug transporter,
putative - Stappia aggregata IAM 12614
Length = 420
Score = 58.0 bits (134), Expect = 5e-07
Identities = 91/381 (23%), Positives = 150/381 (39%), Gaps = 26/381 (6%)
Query: 41 LVVIFLEFFAWGLLTMPIISVL-----NATFPDHT-----FLMNGLIMGIKGILSFLSAP 90
L V+F++ GL+ PII+ L + P T GLI+G+ + F AP
Sbjct: 10 LFVVFVDLLGQGLV-FPIINSLVMEPSTSMLPQSTSDAMRHFDYGLIIGVFFLCWFFGAP 68
Query: 91 LIGALSDVWGRKFFLLVTVFFT----CAPIPLMTINTWWFFAM-ISISGVFAVTFSIVFA 145
I LSDV GRK +L+ +F I +T+N++ + +I+G+ A I A
Sbjct: 69 YISKLSDVIGRKNAILICLFGALGGYALTIAALTLNSFGLLILGRAITGLTAGNQPIAQA 128
Query: 146 YVADVTTEAE-RSRAYGLVSATFAASLVISPALGAYLMD--LYGESLXXXXXXXXXXXXX 202
+ D + + E R+R G + + LV P LG L D L G+
Sbjct: 129 AMIDGSRDDEDRNRNMGYIITGVSFGLVGGPLLGGLLSDPVLLGDLASIKLPFYACFLLV 188
Query: 203 FFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAG 262
++ V S + + +D F L ++ TV+ L V F ++
Sbjct: 189 LIAILLVVFSFKDARDAEAERQKFVFRPSDIFELLWRIRKYPTVMRLTVVFFFFHVANLS 248
Query: 263 QYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEML 322
Y + YL G+G + ++ + +G+ L + +K ++ G+ F +
Sbjct: 249 FYIFVDNYLTSRFGYGTLGGSMVMLTIGIALAFSSTFLVVPAQKRFSKEALL-GMTFTVW 307
Query: 323 QLMWYGF-GSRTWMMWAAGVLA---ALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRG 378
L F S ++ V A G I YP S QG V G+ V
Sbjct: 308 ALSAAAFIASPNALLTYVPVFCFYFAFG-IAYPTFLGLYSAAVNDKEQGWVMGVTIAVFT 366
Query: 379 LCNGLGPAMFGVIFYLFHVDL 399
L G+ + G + L ++DL
Sbjct: 367 LVAGVISLLGGELIGL-NLDL 386
>UniRef50_A7STS4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 432
Score = 58.0 bits (134), Expect = 5e-07
Identities = 70/338 (20%), Positives = 137/338 (40%), Gaps = 16/338 (4%)
Query: 70 TFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWW---- 125
+++ GL++ + S L A L+GA SD GR+ + + +F + ++ + ++
Sbjct: 74 SYMQMGLVLSVS-TPSLLVALLLGAWSDRAGRRRAMAMPIFGSAVESAIILVIMYFELPV 132
Query: 126 -FFAMISI----SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAY 180
F + G F VF+Y+AD+T E++R+ G++ A S ++S +
Sbjct: 133 TFLLLAEFINGSCGFFPTMVLSVFSYIADITEESQRAFRLGILEAIAFISGMLSHLTSGW 192
Query: 181 LMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAAL-RK 239
++ G ++ +PES + V V+S + + K
Sbjct: 193 WINNLGFRAPYWLLLILNTFALLYVTFILPESRAKHVMEKSKVRVLSLDHIRAIVMIFTK 252
Query: 240 VGAERTVLMLCVAVFLSYLPEAGQYSCIFVY-LKLVMGFGVVQVAIFIAI-VGVLSIGVQ 297
+ + + V L + G S +Y L + + + ++ + V ++G
Sbjct: 253 SRDPQRMTIFMVISGLMIVSSIGFGSVFVLYALDRPLCCNAILIGYYLGLSFFVQAVGAV 312
Query: 298 VILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVL---AALGSITYPAIS 354
+ L +L L + VG++ + L+ F + ++ L A LG + P I
Sbjct: 313 LGLKYLRLCLSETALMQVGMVSIISSLVVMAFVTSKKTLFVGKSLPFVACLGGVPTPTIR 372
Query: 355 AYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
A +S AD QG + V + LC LG +F I+
Sbjct: 373 AMMSKMVDADGQGALFAAVASLETLCTLLGALVFNSIY 410
>UniRef50_Q12ZN0 Cluster: Major facilitator superfamily (MFS)
transporter; n=1; Methanococcoides burtonii DSM
6242|Rep: Major facilitator superfamily (MFS)
transporter - Methanococcoides burtonii (strain DSM
6242)
Length = 343
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/306 (22%), Positives = 130/306 (42%), Gaps = 40/306 (13%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F L++ F++ +G++ +P + L F + ++ G I + + AP++G S
Sbjct: 13 LFPLLLISFIDALGFGIV-IPFLVFLVDQFGGNA-IVYGFIGAMYPAFQLIGAPILGRWS 70
Query: 97 DVWGRKFFLLVT-----------VFFTCAPIP-------------LMTINTWWFFAMISI 132
D+ GRK L +T +F P+ ++TI F S
Sbjct: 71 DIHGRKKILFITQAGTLLSWIIFLFAVFTPLKTLIEVDSAVLGTFIITIPLLILFIARSF 130
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL-MDLYGESLXX 191
G+ ++ AY+AD+T E +R++ +G +S + +I P L L + +Y E +
Sbjct: 131 DGLTGGNIAVANAYLADITEEKDRNKNFGKMSISTNLGFIIGPGLAGLLSITIYKELIPV 190
Query: 192 XXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCV 251
I++ +PES K+R T IS+ + +G + ML +
Sbjct: 191 LAAALISLVGTIVILLYLPESRQCKIRTT---KKISFREV--------IGIKNIPYML-L 238
Query: 252 AVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAK 310
FL + Y+ ++ + + V ++ I+ +++G+L I VQ IL +K
Sbjct: 239 LYFLIFFGFNIFYTAFPLHAIRSLQWTVAEMGIYFSVLGILMIIVQGPILSRAVKKYSDV 298
Query: 311 HTIMVG 316
H + G
Sbjct: 299 HLAIAG 304
>UniRef50_Q67KL5 Cluster: Putative sugar transport protein; n=1;
Symbiobacterium thermophilum|Rep: Putative sugar
transport protein - Symbiobacterium thermophilum
Length = 402
Score = 57.6 bits (133), Expect = 7e-07
Identities = 76/337 (22%), Positives = 129/337 (38%), Gaps = 36/337 (10%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIP---LMTINTWWFFAMIS 131
G +M I L+ PL+G LSD +F + AP+ LM I W ++
Sbjct: 44 GYLMTIDNWLALTLTPLVGFLSDRTRTRFGRRIPYLLVFAPLSALFLMLIPVGWETSLWL 103
Query: 132 ISGV-------FAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDL 184
+ G A S + A + DVT RS+A G+++ + +++ GA L +
Sbjct: 104 LLGAAVLMNLSMACWRSPIVALMPDVTPPPLRSKANGIINFMGGLAYIVAMFGGAILYRM 163
Query: 185 Y-GESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAE 243
Y G F+ + PE EK + FA +R +
Sbjct: 164 YPGLPFVASALLLLGITAIFYFFIREPEHSTEK------------SERFQFALIR----D 207
Query: 244 RTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFL 303
R+ + + +A+F ++ + + Y + +G VA + G + + GFL
Sbjct: 208 RSAIFMLLAIFCWFVAYNSLETWVTTYGREHLGMHEADVAGLLTFSGGAFLLFAIPSGFL 267
Query: 304 ------MKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYV 357
K LG K TI+ GLL +L + W L + ++ +I++Y
Sbjct: 268 ADGIGRFKGLGRKRTILGGLLLMILAFFLLDLQANLKSAWYLFALVGF-AWSWVSINSYP 326
Query: 358 SVNSRA--DRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ A + G GM + N GP +FG +F
Sbjct: 327 MITQMAGPGQIGAYTGMYYLFSSMANIAGPPLFGWVF 363
>UniRef50_P0A0J7 Cluster: Quinolone resistance protein norA; n=23;
Staphylococcus|Rep: Quinolone resistance protein norA -
Staphylococcus aureus
Length = 388
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/354 (20%), Positives = 149/354 (42%), Gaps = 19/354 (5%)
Query: 44 IFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKF 103
IFL F GL+ +P++ V T GL++ + + +P G L+D G+K
Sbjct: 12 IFLIFLGIGLV-IPVLPVYLKDL-GLTGSDLGLLVAAFALSQMIISPFGGTLADKLGKKL 69
Query: 104 FLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFA-VTFSIVFAYVADVTTEAERSRAY 160
+ + + + + + M+S I G+ A + V +AD++ ++++ +
Sbjct: 70 IICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIADISPSHQKAKNF 129
Query: 161 GLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPT 220
G +SA + ++ P +G ++ ++ S FIM V P+K +
Sbjct: 130 GYMSAIINSGFILGPGIGGFMAEV---SHRMPFYFAGALGILAFIMSIVLIHDPKKSTTS 186
Query: 221 GWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVV 280
G+ ++ +P L K+ + + + + + LS+ A + + +Y + +
Sbjct: 187 GF------QKLEP-QLLTKINWKVFITPVILTLVLSFGLSAFE-TLYSLYTADKVNYSPK 238
Query: 281 QVAIFIAIVGVLSIGVQV-ILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAA 339
++I I G+ Q+ MK I LL+ ++ L+ F + W +
Sbjct: 239 DISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLVFANGYWSIMLI 298
Query: 340 GVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+ +G + PAI+ Y S N +RQG G+ + + N +GP + G +F
Sbjct: 299 SFVVFIGFDMIRPAITNYFS-NIAGERQGFAGGLNSTFTSMGNFIGPLIAGALF 351
>UniRef50_Q8NBP5 Cluster: Major facilitator superfamily
domain-containing protein 9; n=15; Amniota|Rep: Major
facilitator superfamily domain-containing protein 9 -
Homo sapiens (Human)
Length = 474
Score = 57.6 bits (133), Expect = 7e-07
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+V FL+ F ++ +P++S L+ + + G++ GIL S+ L+G SDV GR
Sbjct: 51 LVGFLDLFGVSMV-VPLLS-LHVKSLGASPTVAGIVGSSYGILQLFSSTLVGCWSDVVGR 108
Query: 102 KFFLLVTVFFTCAPIPLMTINTWWF-FAMISI-SGVFAVTFSIVFAYVADVTTEAERSRA 159
+ LL + + L+ T F F + + +G+F T SI A ++DV E ER
Sbjct: 109 RSSLLACILLSALGYLLLGAATNVFLFVLARVPAGIFKHTLSISRALLSDVVPEKERPLV 168
Query: 160 YGLVSATFAASLVISPALGAYLMDL 184
G + ++ P +G YL +L
Sbjct: 169 IGHFNTASGVGFILGPVVGGYLTEL 193
>UniRef50_Q9RSF5 Cluster: Drug transport protein; n=4;
Deinococci|Rep: Drug transport protein - Deinococcus
radiodurans
Length = 441
Score = 57.2 bits (132), Expect = 9e-07
Identities = 70/266 (26%), Positives = 112/266 (42%), Gaps = 26/266 (9%)
Query: 132 ISGVFA-VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGES 188
I G+F+ T A +AD+++E +R+ + GL+ A F +V PA+G L + L
Sbjct: 150 IGGIFSSATLPTAQAMMADISSEDDRAASMGLIGAAFGLGVVFGPAIGGLLSGISLVAPV 209
Query: 189 LXXXXXXXXXXXXXFFIMVAVPESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVL 247
+F+ VPE+ P + R D + L + G +
Sbjct: 210 YFSAGLGLFTAALAYFM---VPETRHPGQTRTA---------TVDRRSLLSRGG----IP 253
Query: 248 MLCVAVFLSYLPEAGQYSCIFVYLKLVM----GFGVVQVAIFIAIVGVLSIGVQV-ILGF 302
+ A L+ L G I Y++ VM G V +AI G+L+ VQ +
Sbjct: 254 LFLAASALTTLASVGMEQTISFYVQDVMKLDPGETAKTVGKMLAIFGILAALVQGGAIRP 313
Query: 303 LMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVNS 361
L K L I+VGL+ + + W + AA L +GS I P +SA +S++
Sbjct: 314 LSKKLPPTPLILVGLVIMAAGMFLLPQMATYWPITAALALIGVGSAILSPTLSAALSLSV 373
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAM 387
D QG V G+ + L +GP +
Sbjct: 374 GKDGQGAVAGLNSSALALGRMVGPLL 399
>UniRef50_Q8D344 Cluster: YajR protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
YajR protein - Wigglesworthia glossinidia brevipalpis
Length = 388
Score = 57.2 bits (132), Expect = 9e-07
Identities = 44/186 (23%), Positives = 81/186 (43%), Gaps = 13/186 (6%)
Query: 34 EPSVFHALVVIFLEFFAWGL-LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLI 92
E + L +IF F +G+ + +P++S +F + G+ +GI G+ +
Sbjct: 5 EKKFLYVLSIIF-SFRMFGVFMILPVLSNYGMSFNGANSFLIGISIGIYGVTQSIFQIPF 63
Query: 93 GALSDVWGRK------FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAY 146
G LSD +GRK F L++ F C + N W +I G+ A++ S++ A
Sbjct: 64 GLLSDKYGRKNIIIIGFLLIIIGSFICG----IFNNIWIIILGRAIQGMGAIS-SVIMAL 118
Query: 147 VADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIM 206
+ D+T+E R ++ + ++F + +S G L +G F I+
Sbjct: 119 ITDLTSEKNRIKSMAFIGSSFGITFALSIIFGPILAINFGIKSIFWITLFLSILSIFLIL 178
Query: 207 VAVPES 212
+P S
Sbjct: 179 FIIPSS 184
Score = 34.3 bits (75), Expect = 7.2
Identities = 19/84 (22%), Positives = 37/84 (44%)
Query: 282 VAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGV 341
+ I I I GV Q+ G L G K+ I++G L ++ G + W++
Sbjct: 45 IGISIGIYGVTQSIFQIPFGLLSDKYGRKNIIIIGFLLIIIGSFICGIFNNIWIIILGRA 104
Query: 342 LAALGSITYPAISAYVSVNSRADR 365
+ +G+I+ ++ + S +R
Sbjct: 105 IQGMGAISSVIMALITDLTSEKNR 128
>UniRef50_Q890A4 Cluster: Transport protein; n=6;
Lactobacillaceae|Rep: Transport protein - Lactobacillus
plantarum
Length = 410
Score = 57.2 bits (132), Expect = 9e-07
Identities = 83/367 (22%), Positives = 146/367 (39%), Gaps = 27/367 (7%)
Query: 41 LVVIFLEFFAWGLL---TMPIISVLNATFPDHT----FLMNGLIMGIKGILSFLSAPLIG 93
L+V++ F G+ MP +S+ + D T +GL +S +SAPL G
Sbjct: 15 LIVLWFCTFVAGMAFSEIMPFLSLFVSQLGDFTKAQITFYSGLAFAADYAISAISAPLWG 74
Query: 94 ALSDVWGRKFFLLVTVFFTCAPIPLM--TINTWWFFAMISISGVFAVTFSIVFAYVADVT 151
++D GRK LL + LM N W A+ ++ GVFA S A VA T
Sbjct: 75 IIADKKGRKIMLLRASLGMAVAMGLMGFVTNVWQLVALRALQGVFAGFISNAQALVASQT 134
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPE 211
RA + + + P +G L L+ S+ F++
Sbjct: 135 PRKYSGRALSTLITGAVSGQLFGPVIGGLLAQLF--SIRNTFFITAGLLMVAFLLSLF-- 190
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
+ E +P + +P AA + ++MLC + + A I +Y+
Sbjct: 191 FVQEHFKPVAHHRE-PGDSRNPLAAFQ--NPRLIIVMLCSTAIVQF-GNASIAPIISLYV 246
Query: 272 KLVMGF-GVVQV--AIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYG 328
+ +M + G + V I A+ G+ +I LG G+ ++ G +F + +M++
Sbjct: 247 RELMHYRGPITVVAGIIAALPGISNIFSAPRLGRYGDQHGSGKVLLFGYIFAV--IMYFP 304
Query: 329 FGSRTWMMWAAGVLA-ALG---SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLG 384
G T ++ A G+L A+G YP I ++ N+ + + + N G
Sbjct: 305 QGIVTSVV-ALGILRFAIGISDGALYPEIQTVLTKNTPVHLTSTIFSYNQSFQAIGNMFG 363
Query: 385 PAMFGVI 391
+ G++
Sbjct: 364 ALLGGLV 370
>UniRef50_Q2ARG1 Cluster: General substrate transporter:Major
facilitator superfamily MFS_1; n=4; Bacillus|Rep:
General substrate transporter:Major facilitator
superfamily MFS_1 - Bacillus weihenstephanensis KBAB4
Length = 399
Score = 57.2 bits (132), Expect = 9e-07
Identities = 56/299 (18%), Positives = 119/299 (39%), Gaps = 14/299 (4%)
Query: 91 LIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFS-IVFAYV 147
L GA+SD +GRK + + + + I + +W + + G+ A TFS + AYV
Sbjct: 70 LFGAISDKYGRKKVIFIGLLALSIVSFFLGIVDSLFWLVILRGLQGIAAATFSPVALAYV 129
Query: 148 ADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMV 207
++ ++ G VS F + + + + +G + +I
Sbjct: 130 VEMFPVEKKVTTIGFVSTGFLVAGIAGQVISTAVSQHFGWHMVFFLLSIVYIITAVWIHY 189
Query: 208 AVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCI 267
++P+ + GP+ + KV +++++ + F+ + Y+ +
Sbjct: 190 SLPKGEMSQSNTDILGPI---------KQMGKVFTHKSLVLSYMIAFVLLMAFVNMYTVL 240
Query: 268 FVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWY 327
YL + + ++ + G+ + + + G L K G + + GLL + L
Sbjct: 241 GNYLSSPTYNLIPEQILYFRLAGLFGMLLSPLAGRLTKRFGVRQVLQGGLLVAIFSLSSM 300
Query: 328 GFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGP 385
GF S ++ + +G +I+ P++ + V R G+ + T V L +GP
Sbjct: 301 GFISNLPLLVMMSICFVIGIAISVPSLVSLVGQLGGKSR-GIAVSIYTFVLFLGTSIGP 358
>UniRef50_A5EUI4 Cluster: Putative Permease of the major facilitator
superfamily; putative Multidrug-efflux transporter; n=1;
Bradyrhizobium sp. BTAi1|Rep: Putative Permease of the
major facilitator superfamily; putative Multidrug-efflux
transporter - Bradyrhizobium sp. (strain BTAi1 / ATCC
BAA-1182)
Length = 426
Score = 57.2 bits (132), Expect = 9e-07
Identities = 83/375 (22%), Positives = 153/375 (40%), Gaps = 37/375 (9%)
Query: 38 FHALVVIFLEFFAWGLLT--MPIISVLNATFPDHTFLMN--GLIMGIKGILSFLSAPLIG 93
F L+ IF +G++ +P + A D T L G + G+ + FL AP G
Sbjct: 16 FALLLGIFAVAVGYGIVMPILPFVIERLAMTADATTLSRHTGFLAGVYALAIFLFAPAWG 75
Query: 94 ALSDVWGRK---------FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFS-IV 143
+SD GR+ F + + +F +PL+ + + ++G+FA +
Sbjct: 76 RVSDQRGRRPVIVTGLVGFAITLGIFVLADSLPLLYVGRF-------LAGLFAAAVAPAA 128
Query: 144 FAYVADVTTEAE-RSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXXX 201
+A V D E R+ + L++ AA P +G ++ + E++
Sbjct: 129 YALVCDHAPSDEWRAHRFALINVAGAAGSFAGPTVGGMILQARFAEAIAGRFTSP----- 183
Query: 202 XFFIMVAVPESLPEKVRPTGWGPVISWEQADPFA-ALRKVGAERTVLMLCVAVFLSYLPE 260
++ AV +L + G P + + A A G VL LC +F++
Sbjct: 184 ---VVAAVSVALAAALAIQGLVPATAQRKDSEMAFAASAPGDRELVLRLCGLMFVTTAAV 240
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLF 319
+ + + K V+ Q+ A G++ + VQ ++ L+K + + GL+
Sbjct: 241 SAFDVGLLLRGKQVLRMDAWQLGAMFAECGLVMLFVQAIVFSPLIKPQTTRWFLTPGLIA 300
Query: 320 EMLQLMWYGFGSRTWMMWAAG--VLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVR 377
L+ S ++++ + G V+AA + YP ++ +V + S R G G VT
Sbjct: 301 LTAGLIAIPLAS-SYVLTSVGIAVVAAGAGLVYPIVTYWVPLGSNGTR-GADLGRVTAAA 358
Query: 378 GLCNGLGPAMFGVIF 392
L LG G++F
Sbjct: 359 SLGQALGSTAGGLLF 373
>UniRef50_Q2RM84 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
Major facilitator superfamily MFS_1 precursor - Moorella
thermoacetica (strain ATCC 39073)
Length = 406
Score = 56.8 bits (131), Expect = 1e-06
Identities = 74/354 (20%), Positives = 149/354 (42%), Gaps = 23/354 (6%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTC 113
+ +P++ ++ ++ + T + L + + + + P G LSD +GRK + +
Sbjct: 25 MLVPLLPLMRSSL-NVTLVQVSLFITAFSLPAGIVIPFAGFLSDCYGRKTIMAPALIIYG 83
Query: 114 APIPLMTINTWW----FFAMIS---ISGVFAV-TFSIVFAYVADVTTEAERSRAYGLVSA 165
A L + W ++ ++ + G+ A T+ + A +D+ ER++A GL+ A
Sbjct: 84 AGGILAGLAAWLVASPYYLILGSRILQGIGAGGTYQLAMALASDIFQSNERTKALGLLEA 143
Query: 166 TFAASLVISPALGAYL-MDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGP 224
V+SP GA L + L+ + +V PE T +
Sbjct: 144 ANGLGKVVSPIAGAALGLLLWFAPFFVYGILAIPIGLAVWFLVREPEQ--GNKNKTDFHS 201
Query: 225 VISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAI 284
+ + + ++L + +F+ + G S + L+ G +++ +
Sbjct: 202 Y--FHNLGQVLQEKGLSLMASILAGMIVLFILF----GVLSYVSDLLEGRYGVTGIRIGL 255
Query: 285 FIAI-VGVLSIGVQVILGFLMKSLG--AKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGV 341
IAI VG +++ + +L K+ G K I+ GL+ E L+ GF + ++ + A +
Sbjct: 256 LIAIPVGTMALTSYLSGSYLQKTAGNFLKIVIIAGLVLEAAALVIMGFFANIYIFFLAMI 315
Query: 342 LAALGS-ITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
L G+ I PA++ ++ S +R G+ + R LGP FG+ L
Sbjct: 316 LMGFGTGIVLPAVNTLITSASARERGGIT-CLYGSARFFGVALGPPAFGLAMTL 368
>UniRef50_Q1AYP7 Cluster: Major facilitator superfamily MFS_1; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Major facilitator
superfamily MFS_1 - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 450
Score = 56.4 bits (130), Expect = 2e-06
Identities = 81/350 (23%), Positives = 128/350 (36%), Gaps = 24/350 (6%)
Query: 56 MPI-ISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCA 114
MP+ + L P GL+ L+APL G L+D +G K LL F A
Sbjct: 72 MPLYVQQLGVEDPGRAAAWAGLLNTATAATMALAAPLWGRLADRFGPKPMLLRATFAGAA 131
Query: 115 PIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLV 172
+ +M + + W + + G T + VA + G + A+
Sbjct: 132 VVGVMGLAASPWHLLGLRLLQGTLTGTVAAATLLVAATAPAGRAGQRLGTLQTVIFAAAA 191
Query: 173 ISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES-LPEKVRP---TGWGPVISW 228
P LG DL G I++ V + P + P G G + W
Sbjct: 192 AGPFLGGVFADLVGIRASFGVTSGLLALSAVLILLGVDGARAPAEGAPRAQEGAGGGVPW 251
Query: 229 EQADP-FAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIA 287
P AAL V A T + + F++ L E + S + ++G G + A+ A
Sbjct: 252 LGLVPVLAALFVVQASNTGVAPALPGFVAGLME--EPSGVASLAGQILGAGALAAALGSA 309
Query: 288 IVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAA--L 345
G L+ + LGA+ I L+ L + S +W V A+ +
Sbjct: 310 AGGRLA-----------ERLGARTVIFCSLVLGGLAFLPQAAVSSVAALWVLRVAASFFI 358
Query: 346 GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
G++ P + V DRQG G+ V + G+GP G++ F
Sbjct: 359 GAVV-PVANLAVRQAVPPDRQGRAFGVAASVTSVAFGVGPLGGGLLASAF 407
>UniRef50_A5ALX6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 408
Score = 56.4 bits (130), Expect = 2e-06
Identities = 68/310 (21%), Positives = 123/310 (39%), Gaps = 31/310 (10%)
Query: 39 HALVVIFLEFFAWGLLTMPIISVLNATF-PDH-----TFLMNGLIMGIKGILSFLSAPLI 92
H + +FL FA ++ I V A P + G I G+ + + PL+
Sbjct: 9 HLFMTVFLFNFATFMVIPAITDVTMAALCPGRDECSIAIYLTGFQQVIIGLGTLVMMPLV 68
Query: 93 GALSDVWGRKFFLLVTVFFTCAPIPLMTINT-----WWFFAMISISGVF--AVTFSIVFA 145
G LSD++GRK L + + T P+ ++ + + +F + +++ + + A
Sbjct: 69 GNLSDMYGRKALLTIPMCLTIIPLAILAWSRSRNFFYAYFVLKTLTSMVCEGSVHCLTLA 128
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFI 205
YVAD E R+ A+G++S +++ V +L + F+
Sbjct: 129 YVADNIPEIRRASAFGVLSGVGSSAFVCGTLSARFLKTSSTFQVAASVAAVAAVYMKLFL 188
Query: 206 M----------VAVPESLPEKVRPTGW----GPVI-SWEQADPFAALRKVGAERTVLMLC 250
A+ E P + G PV S D +L + + T
Sbjct: 189 PDSVIKDGVLDRAILEQKPCVIHLDGESAQDSPVFKSMPSLDDMLSLLQTSS--TFTKAA 246
Query: 251 VAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVL-SIGVQVILGFLMKSLGA 309
+ F S L + G ++ + YLK F Q A + I G+ +I V++ L ++G
Sbjct: 247 IVAFFSNLGDVGLHTSLMYYLKARFHFNKHQFADLMMISGIAGTISQLVLMPILAPTIGE 306
Query: 310 KHTIMVGLLF 319
+ + +GLLF
Sbjct: 307 EKLLAIGLLF 316
>UniRef50_Q0VSH1 Cluster: Major facilitator family transporter; n=1;
Alcanivorax borkumensis SK2|Rep: Major facilitator
family transporter - Alcanivorax borkumensis (strain SK2
/ ATCC 700651 / DSM 11573)
Length = 455
Score = 56.0 bits (129), Expect = 2e-06
Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV--TVFF 111
+ +PI +V + L+ G +G G++ L G LSD +GR+ LL+ +F
Sbjct: 33 MILPIFAVYGQALEGASPLLIGTAIGAYGLMQALLQIPFGMLSDRFGRRPLLLIGLLLFI 92
Query: 112 TCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASL 171
+ M+ + + A ++ G A+ S++ A + DV TE R+RA L+ + S
Sbjct: 93 AGGAVAAMSDHIYGVIAGRALQGAGAIA-SVIMALIGDVVTEKHRTRAMALIGMSVGGSF 151
Query: 172 VISPALGAYLMDLYGES 188
V++ LG L G S
Sbjct: 152 VLALILGPLLAGWLGLS 168
>UniRef50_A7S0P7 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 438
Score = 55.6 bits (128), Expect = 3e-06
Identities = 75/355 (21%), Positives = 141/355 (39%), Gaps = 22/355 (6%)
Query: 59 ISVLNATFPDHTFLMNGLIMGIK-GILSFLSAP------LIGALSDVWGRKFFLLVTVFF 111
I++LNAT + L + GI+ F + P LIG+ +D GR+ L +
Sbjct: 57 ITILNATMQHIEQEVQSLASYVHLGIVMFAALPSVVMSLLIGSWTDSRGRRPALFLPALG 116
Query: 112 TCAP--IPLMTINTWW----FFAMISISGVFAVTFSIVF---AYVADVTTEAERSRAYGL 162
+ + ++ + W F SI+G+ +I+ AY+AD T E +RS +
Sbjct: 117 STLESIVVILVMYFEWPIYVLFVGASINGLCGSFTTIIMGTMAYIADTTHEDQRSLRLAI 176
Query: 163 VSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKV--RPT 220
+ ++S ++ Y + ++ VPES P V T
Sbjct: 177 LEFMVFFGAMVSQLTSGLWIEKYSFIIPYWFILSCLSLSCILVIAIVPESRPPDVIQNKT 236
Query: 221 GWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVY-LKLVMGFGV 279
+ S + + G R + +L ++ ++ L G I ++ L + F
Sbjct: 237 AFCSCRSLQNVYKVYMTPREGGRRNLFLLTLSSGVTNLILQGVAGVIVLFVLHTPLCFSP 296
Query: 280 VQVAIFIAIVGVLSIGVQVILGF--LMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW 337
V +++ + LSIGV +LG L + L + VG+L M + +GF ++ ++++
Sbjct: 297 KLVG-YLSALRYLSIGVGAVLGIKVLGRWLSVINISRVGMLSTMASYILFGFSTKIFIVF 355
Query: 338 AAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
P + +S D QG + V + LC+ G +F ++
Sbjct: 356 LVPFAGLFMGCVVPILRGIMSRIVSQDEQGALFSAVASLEMLCHLCGTFLFNSLY 410
>UniRef50_A7EBM9 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 595
Score = 55.6 bits (128), Expect = 3e-06
Identities = 47/150 (31%), Positives = 68/150 (45%), Gaps = 14/150 (9%)
Query: 80 IKGILSFLSAPLIGALSDVWGRKFFLLVTVF--FTCAPIPLM------TINTWWFFA--- 128
I GI S + +PL+GA SD GRK L ++ F I ++ T++ W A
Sbjct: 160 ITGIFSAVMSPLLGAWSDRNGRKKILAISSLGGFLTEIITILAGKYPDTVSYQWLLAGAV 219
Query: 129 MISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGES 188
+ G F ++ AY AD T ++R+ A+ A A + I P L A L L +S
Sbjct: 220 FDGLCGSFTAGMALTHAYAADCTAPSKRAVAFAYFHACLFAGVAIGPLLAAALFHL-TQS 278
Query: 189 LXXXXXXXXXXXXXF--FIMVAVPESLPEK 216
L F FI++ VPESL +K
Sbjct: 279 LLTVFYVALGIHTFFILFIVLVVPESLTQK 308
>UniRef50_Q8CX74 Cluster: Multidrug resistance protein; n=1;
Oceanobacillus iheyensis|Rep: Multidrug resistance
protein - Oceanobacillus iheyensis
Length = 399
Score = 55.2 bits (127), Expect = 4e-06
Identities = 87/363 (23%), Positives = 141/363 (38%), Gaps = 32/363 (8%)
Query: 48 FFAWGLLTM--PIISVLNATFPD----HTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
FF G +TM P IS+ + D + +GL + I +F+ +P+ G + D +GR
Sbjct: 6 FFISGSMTMVVPFISLYIESMGDFSEGYVQTWSGLTFAVTFITAFIFSPIWGRIGDRYGR 65
Query: 102 KFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRA 159
K ++ + F + LM W F + G+ + A++A T + +
Sbjct: 66 KKIMIASAFGIGFSVFLMGFADTVWQLFLLRLFMGIVTGFIPMSQAFIATQTPKEVAGKV 125
Query: 160 YGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRP 219
G + ++ P LG L D +G + ++ V E L K
Sbjct: 126 LGTLQTGTITGSLMGPLLGGALADAFGYTSTFKWVAITIFISGLLVLFGVKE-LKMK--- 181
Query: 220 TGWGPVISWEQADPFAALRKVGAERTVL--MLCVAVFLSYLPEAGQYSCIFVYLKLVMG- 276
S + D RK + + +L V + LS L + +S I L L +
Sbjct: 182 ------FSNNENDTKKYSRKEVLQHILQKPVLFVVMLLSALVQIAHFS-IQPILSLFVAE 234
Query: 277 -FGVVQVAIFIAIV-GVLSIGVQVILGFLMKSLGAKH---TIMVGLLFEMLQLMWYG-FG 330
G V +A F I +G +++ +G H I++ LLF + G F
Sbjct: 235 IHGPVNLAFFAGIAFSAAGLG-NLLMARRWGIIGDNHGYVKILIILLFAAGFVYLPGIFV 293
Query: 331 SRTWMMWAAGVLAAL--GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
+ W + L L G I P AY+ + QG V G T +R L N +GPA+
Sbjct: 294 TNIWQLVILRFLLGLSIGGIV-PLRIAYIRQEAPLSMQGEVLGYNTSLRFLGNIIGPALG 352
Query: 389 GVI 391
G I
Sbjct: 353 GTI 355
>UniRef50_Q9V395 Cluster: CG5760-PA; n=5; Endopterygota|Rep:
CG5760-PA - Drosophila melanogaster (Fruit fly)
Length = 477
Score = 55.2 bits (127), Expect = 4e-06
Identities = 68/340 (20%), Positives = 134/340 (39%), Gaps = 18/340 (5%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS 131
L G + + L F+++P++G LSD +GRK LL + ++ + +++
Sbjct: 111 LFGGFLGSMFSFLQFVASPIVGGLSDYYGRKPVLLACASGIALSYLIWACSSNFALFVLA 170
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALG---AYLMDLYG 186
+ G+ S+ + + DV++ R R LV F+ ++ P +G A D G
Sbjct: 171 RFVGGISKGNISLCMSVITDVSSVKTRGRGMALVGVAFSLGFIVGPMIGALFAIFSDKSG 230
Query: 187 ES---LXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWE-QADPFAALRKVGA 242
+ L + + E+LP++ R +S+ Q F+A+ + A
Sbjct: 231 STWFVLPSLLAFGLAVGDLVVLACCLRETLPKEKRVKEISSALSYGLQLLNFSAIFRFAA 290
Query: 243 ERTVLMLCVA----VFLSYLPEAGQYSCIFVYLKLVM----GFGVVQVAIFIAIVGVLSI 294
+ V +A + L Y YS + + +M G+ + A GV+
Sbjct: 291 IKNVPKKDIAALRSIGLVYFLYLFLYSGLEFTVTFLMYHKFGYTSMDQAKMFLTTGVIMT 350
Query: 295 GVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAI 353
+Q + + K + L + + G + M++A L A+ + +
Sbjct: 351 LLQGSVVRRLPEAKIKGYAIFSLYLIVPAFVVVGLAEGSRMLYAGMTLFAISTAFAVTCL 410
Query: 354 SAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
+ VS D++G V G+ + L LGP + + F+
Sbjct: 411 TTLVSKYGNDDQKGSVLGIFRSLGALARALGPVVGCIAFW 450
>UniRef50_Q7UXH6 Cluster: Probable MFS transporter; n=1; Pirellula
sp.|Rep: Probable MFS transporter - Rhodopirellula
baltica
Length = 429
Score = 54.8 bits (126), Expect = 5e-06
Identities = 67/294 (22%), Positives = 124/294 (42%), Gaps = 20/294 (6%)
Query: 86 FLSAPLIGALSDVWGRKFFLLVT---VFFTCAPIPLMT----INTWWFFAMISISGVFAV 138
FL+ P G L+D ++ L+ T + F A + + T I W AM I G+ V
Sbjct: 88 FLAIPA-GVLADRIDKRHLLIGTQSILLFVTAMLAVSTATGVITAWGLLAMTFIIGLGMV 146
Query: 139 TFSIVF-AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXX 197
+ + + ++ + SRA GL S +F + + PA+G L+ L G
Sbjct: 147 VHVPTWQSAIPELVPRWQISRAVGLGSISFNLARAVGPAIGGVLIALLG-IWSTFAINAI 205
Query: 198 XXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSY 257
+++ E R G S Q +R V +RT+ + + V L
Sbjct: 206 SFAGVLTVLIRWQRDTTETSR--GRSFFSSMRQ-----GIRYVALKRTMRHVMLGVVLFV 258
Query: 258 LPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGL 317
LP + +S + +Y K +G+G I +A++GV ++ +L + LG+ TI +
Sbjct: 259 LPGSALWSLMPLYAKTALGWGAQGFGILVAMIGVGAVVGASMLPRVRSRLGSDRTIAAAM 318
Query: 318 LFEMLQLMWYGFGSRTWMMWAAGVLAALG---SITYPAISAYVSVNSRADRQGV 368
+ ++ ++ AA +L G ++T +A +++ SR +G+
Sbjct: 319 TLYAIGMLTLSSEPAWPILLAATLLMGCGWMATLTTLNATAQITLPSRLRARGM 372
>UniRef50_Q21M22 Cluster: Major facilitator superfamily MFS_1; n=1;
Saccharophagus degradans 2-40|Rep: Major facilitator
superfamily MFS_1 - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 471
Score = 54.8 bits (126), Expect = 5e-06
Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTC 113
+ +PI+ + +P T GL +GI G+ + +G LSD GRK ++ + C
Sbjct: 47 MVLPILVLYAGDYPGATPFTLGLALGIYGLTQAVFQIPLGLLSDFIGRKPVIIAGLLVFC 106
Query: 114 APIPL--MTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSA----TF 167
A L + W ++ G A+ S + A VAD+T+E R++A + A +F
Sbjct: 107 AGSVLAGTAESVEWLIIGRALQGSGAIA-STIMAMVADLTSEQNRTKAMAAIGASIGLSF 165
Query: 168 AASLVISPALGAY 180
+ ++++ P +GA+
Sbjct: 166 SLAMILGPTVGAF 178
>UniRef50_Q15ZK9 Cluster: Major facilitator superfamily MFS_1
precursor; n=3; Proteobacteria|Rep: Major facilitator
superfamily MFS_1 precursor - Pseudoalteromonas
atlantica (strain T6c / BAA-1087)
Length = 447
Score = 54.8 bits (126), Expect = 5e-06
Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 3/149 (2%)
Query: 40 ALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
AL +++ + MP++++L +PD++ LM GL +G G+ + +G LSD
Sbjct: 11 ALAAVYVLRMLGLFMVMPVLAILAVHYPDYSALMLGLAIGGYGLTQAILQIPMGVLSDKI 70
Query: 100 GRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERS 157
GRK ++ + +F + + + W + G A+ +I+ A DV+ E +R
Sbjct: 71 GRKPVIVGGLLMFAIGSGVAATADSMLWIVIGRFLQGAGAIAGAIM-ALAGDVSREQQRP 129
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYG 186
+ ++ S I+ +G + D YG
Sbjct: 130 KVMAIIGIAIGFSFYIALLIGPVIADNYG 158
>UniRef50_Q0FEF9 Cluster: Drug resistance transporter, Bcr/CflA
subfamily protein; n=1; alpha proteobacterium
HTCC2255|Rep: Drug resistance transporter, Bcr/CflA
subfamily protein - alpha proteobacterium HTCC2255
Length = 401
Score = 54.8 bits (126), Expect = 5e-06
Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Query: 56 MPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAP 115
+P ++ + + F +MN + G + + L +IG LSD +GR+ LL +V C
Sbjct: 30 LPSLANMASEFNVSYRVMNISVAGYLAVTAILQI-IIGPLSDRYGRRIVLLSSVIIFCLS 88
Query: 116 IP--LMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVI 173
+ + N WWF + G ++ A V D+ E + +++ A ++
Sbjct: 89 TIGCIFSSNIWWFLFFRILQGAMISGTALSRAIVRDMMDSKEAVKVLSIIAMAMAIVPML 148
Query: 174 SPALGAYLMDLYG 186
+P +G +L +LYG
Sbjct: 149 APMIGGFLDELYG 161
>UniRef50_A4WGP8 Cluster: Major facilitator superfamily MFS_1
precursor; n=4; Proteobacteria|Rep: Major facilitator
superfamily MFS_1 precursor - Enterobacter sp. 638
Length = 416
Score = 54.8 bits (126), Expect = 5e-06
Identities = 76/319 (23%), Positives = 129/319 (40%), Gaps = 34/319 (10%)
Query: 87 LSAPLIGALSDVWGRK------FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTF 140
LSA + G+L D +G K L CA +P + + A+ + F +T
Sbjct: 65 LSAVIAGSLGDRFGLKRVLVMGLMLFAVACLLCAVMPDLRLLVG-ARALQGVGAAFLMTL 123
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
S+ A + V A+ RA G++ A + P+LG L+ L G
Sbjct: 124 SM--ALMRQVAGSADIGRAMGILGTVSALGTALGPSLGGLLLPLTGWRGVFWIQVPLAVL 181
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
+ A+P+ K +P G G P + RK+ + V ML AV ++ L
Sbjct: 182 TIILAVTALPDEAI-KCKPAGSG------LKTPLS--RKIISSLFVNMLVAAVMMTTLV- 231
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFE 320
G + +L +G V V + + I V+SI + G L+ LG++ + G+
Sbjct: 232 VGPF-----FLSSGLGMNSVHVGLVMTIGPVISIFSGIPSGRLVDRLGSRLIVAAGI--S 284
Query: 321 MLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRA-------DRQGVVQGMV 373
+L + +M G + +L +T P + + N+ A DR+G V GM+
Sbjct: 285 LLAAGTFLMAGLPQIMGVPGYIISLAVLT-PGYQLFQAANNTAVLSDVRDDRRGTVSGML 343
Query: 374 TGVRGLCNGLGPAMFGVIF 392
+ R + G + G +F
Sbjct: 344 SFSRNVGLIAGASAMGAVF 362
>UniRef50_Q31IV1 Cluster: Major facilitator superfamily (MFS)
transporter; n=1; Thiomicrospira crunogena XCL-2|Rep:
Major facilitator superfamily (MFS) transporter -
Thiomicrospira crunogena (strain XCL-2)
Length = 462
Score = 54.4 bits (125), Expect = 6e-06
Identities = 79/352 (22%), Positives = 139/352 (39%), Gaps = 18/352 (5%)
Query: 54 LTMPIISVL-NATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV--TVF 110
+ P+ ++ + F T G+ MGI G+ + G LSD +GRK ++V VF
Sbjct: 32 MIFPVFALFAHEEFQGVTATQIGIAMGIYGLTQAVLQIPYGMLSDRFGRKPLIIVGMLVF 91
Query: 111 FTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAAS 170
+ + M + +I G+ AV +++ A VAD+ TE R RA +V T S
Sbjct: 92 MLGSIVCAMADSIEMMIVGRAIQGMGAVA-AVLMATVADLVTEQFRLRAMSIVGMTIGLS 150
Query: 171 LVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQ 230
+S +G L +L+G ++ AVP+ + + +
Sbjct: 151 FTLSLVVGPMLGELFGVRGIFWVIAGLGVLGIVLVLFAVPKIENQTFQREA--------E 202
Query: 231 ADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVG 290
ADP + + V +L L + VF+ + + I ++ G + V
Sbjct: 203 ADP-SQFKDVIKNPQLLRLDIGVFVLHAILTAMFIAIPFMIRDNAGLDSLHHWELYLPVM 261
Query: 291 VLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITY 350
+LS + V +S G I VG + + LM GF W VL + +
Sbjct: 262 LLSFVLMVPFIIQAESKGRMKPIFVGAIL-TIALMQLGFLFEANGFWTMFVLLLIFFTAF 320
Query: 351 PAISA----YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHVD 398
+ A V S AD++G G+ + + L G + G + ++ ++
Sbjct: 321 NLLEASLPSLVVKLSPADKKGTASGVYSSSQFLGAASGGFIGGWFYEMYGLE 372
>UniRef50_Q122U2 Cluster: Major facilitator superfamily MFS_1
precursor; n=12; Burkholderiales|Rep: Major facilitator
superfamily MFS_1 precursor - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 424
Score = 54.4 bits (125), Expect = 6e-06
Identities = 51/175 (29%), Positives = 78/175 (44%), Gaps = 11/175 (6%)
Query: 54 LTMPIISVLNATFPDHTFLMN-GLIMGIKGILSFLSAPLIGALSDVWGRKFFLL--VTVF 110
L +P+ ++ A +P GL MGI G+ + G SD WGRK ++ + +F
Sbjct: 25 LVLPVFALEAAKYPGGDDPARVGLAMGIYGLTQGVLQIPFGIASDWWGRKRVIIAGLLLF 84
Query: 111 FTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSAT---- 166
+ + + W A S+ G A++ + V A +AD T + R++A LV A+
Sbjct: 85 ALGSFVATWAPDLDWLIAGRSLQGAGAIS-AAVTALLADSTRDEVRTKAMALVGASIALM 143
Query: 167 FAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTG 221
FA SLVI+P L Y+ L+G L + PE L RP G
Sbjct: 144 FALSLVIAPLLAGYI-GLHG--LFALTGALALGGIAVVLWWVPPEPLDHVNRPRG 195
>UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE46682p
- Drosophila melanogaster (Fruit fly)
Length = 599
Score = 54.4 bits (125), Expect = 6e-06
Identities = 69/316 (21%), Positives = 125/316 (39%), Gaps = 26/316 (8%)
Query: 90 PLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVAD 149
P++G V G L++ V+F AP+ + F S+SG + VF+Y+AD
Sbjct: 171 PVVGEFLGVVG----LMLCVYFEQAPMEAAALTEAIF---PSLSGGWFTMLMGVFSYIAD 223
Query: 150 VTTEAERSRAYGLVSATFAASLVISPALGAYLM---DLYGESLXXXXXXXXXXXXXFFIM 206
+TTE +R+ G+++ F+ + I A L+ YG FF +
Sbjct: 224 ITTEEDRTLRIGILNVCFSVGVPIGMAFSGVLLKQIGFYGVFSISAAFYVIAFVYGFFFL 283
Query: 207 VAVPESLPEK--VRPTGWGPVISWEQ-ADPFAALRKVG---AERTVLMLCVAVFLSYLPE 260
P+S PEK + + E F K G + V++L + V + P
Sbjct: 284 -EEPQSRPEKSAEQKSLLADFFDKEHVVQTFRVAFKKGENQRRKRVILLMIVVMVIIGPL 342
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLS-IGVQVILGFLMKSLGAKHTIMVGLL- 318
G+ + +++ + + V+ + F IGV +G L L +VG+L
Sbjct: 343 HGEMAVTYLFTRFRFNWSEVEFSFFSTYAMFTGLIGVIFCVGILSHKLNIDDA-LVGVLS 401
Query: 319 --FEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGV 376
++L Y F + M+ G++ + A+ + + D G V +
Sbjct: 402 STSKILSSFVYAFATLPRHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLF--- 458
Query: 377 RGLCNGLGPAMFGVIF 392
G+ L P +F ++
Sbjct: 459 -GVAEALMPMVFAPMY 473
>UniRef50_Q0W1D9 Cluster: Permease; n=1; uncultured methanogenic
archaeon RC-I|Rep: Permease - Uncultured methanogenic
archaeon RC-I
Length = 410
Score = 54.4 bits (125), Expect = 6e-06
Identities = 75/324 (23%), Positives = 135/324 (41%), Gaps = 29/324 (8%)
Query: 40 ALVVIFLEFFAWGLLTMPIISVLN--ATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSD 97
AL+V+F+ F L+ I+ +L A+ + M GL+ I L+AP++G LSD
Sbjct: 18 ALLVVFIAIFTDMLIYCMIVPILPEYASGLGASQQMIGLLFASYAITFLLAAPVVGVLSD 77
Query: 98 VWGRKFFLLVTV--FFTCAPIPLMTINTWWFFAMISISGVFA-VTFSIVFAYVADVTTEA 154
GRK +LV + F + + + F ++ GV A T++ A ++D+
Sbjct: 78 RVGRKLPMLVGLLGLFGSTLLFAFSSDLTMLFVARALQGVSAGATWTAGLALLSDLFPPK 137
Query: 155 ERSRAYGL-VSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXF--FIMVAVPE 211
R +A G+ +S +FA +L + P G L + G +L +++ P
Sbjct: 138 MRQQAIGIGISGSFAGTL-LGPLFGGALYEYGGYALPFLAAAGLVLIDGIARLLLLKDPP 196
Query: 212 SLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYL 271
LP A+ +L+ + RT+L++ + L A + +YL
Sbjct: 197 RLP----------------AEQQVSLKSMLKNRTILLMAGVIVLVSAATALLEPVLPLYL 240
Query: 272 KLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQL----MWY 327
V+ + + A+ V S+ + + + G K I+ GL+ L L +
Sbjct: 241 SDVLKVSPTMIGLLFAVTVVASLIASPLSYKVAERFGRKRVIIAGLICSALILPTLALSG 300
Query: 328 GFGSRTWMMWAAGVLAALGSITYP 351
F +M A G + A+G + P
Sbjct: 301 SFILEVVLMAALGGVLAIGLASVP 324
>UniRef50_Q5L371 Cluster: Drug-efflux transporter; n=2;
Geobacillus|Rep: Drug-efflux transporter - Geobacillus
kaustophilus
Length = 410
Score = 54.0 bits (124), Expect = 8e-06
Identities = 70/334 (20%), Positives = 136/334 (40%), Gaps = 22/334 (6%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAM 129
+ GL+ + + + + AP+ G +D +G++ L+ M + A+
Sbjct: 45 IWTGLVFSVTFLSAAVMAPIWGVFADKYGQRANLIRAGIGMGLITGCMAFAASPMTLLAL 104
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
+ G F+ ++ F+Y+A V A G + A +I P +G L DL+G
Sbjct: 105 RFLVGFFSGFITVSFSYLARVVPRDHSGEALGTLQTGSIAGNIIGPLIGGALSDLFG--- 161
Query: 190 XXXXXXXXXXXXXFFIMVAVPESL-PEKVRPTGWGPVISWEQADPFAALRKVGAERTVLM 248
++ +P EK PV+ + + A+ ++V R +++
Sbjct: 162 ---FRPVFLVTGLCILLTLLPVIFWLEK------DPVVPQTKENK-ASFKEVFRHRPLIV 211
Query: 249 LCVAVFLSYLPEAGQYSCIFVYLKLVMGFG---VVQVAIFIAIVGVLSIGVQVILGFLMK 305
L +A FL + G S + ++++ ++G + +I G+ +I LG L
Sbjct: 212 LFIATFLVQIAVLGVNSMMTIFVQSLIGHSSNLAFLSGLASSITGIATIIGAPYLGKLGD 271
Query: 306 SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAAL--GSITYPAISAYVSVNSRA 363
+G + T+ + L+ L + + + ++ L L G + +P+I A ++ S
Sbjct: 272 RIGQEKTLPILLVLSGLFALPQVWTDNIYELYVWRFLQGLVVGGV-WPSIQALINAQSPR 330
Query: 364 DRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLFHV 397
QG V G+ R L N GP G I F +
Sbjct: 331 RIQGRVFGVTASSRFLGNLTGPTAAGAIAGFFSI 364
>UniRef50_Q1V9Z1 Cluster: Putative sugar transport protein; n=1;
Vibrio alginolyticus 12G01|Rep: Putative sugar transport
protein - Vibrio alginolyticus 12G01
Length = 389
Score = 54.0 bits (124), Expect = 8e-06
Identities = 70/320 (21%), Positives = 125/320 (39%), Gaps = 25/320 (7%)
Query: 40 ALVVIFLEFFAWGLLT--MPIISVLNATFPDHTFLMN--GLIMGIKGILSFLSAPLIGAL 95
+L + L +G++T + II +L D + GL++ + ++ +S P I L
Sbjct: 5 SLFIFALSLAVFGVITTELGIIGLLPQVMKDFNIDVQEAGLLVSVYAVVVAVSGPFITLL 64
Query: 96 SDVWGRKFFL--LVTVFFTCAPIPLMTIN-TWWFFAMISISGVFAVTFSIVFAYVADVTT 152
W RK+ L ++++F + +T + T I + + AV FS+ +
Sbjct: 65 MSGWNRKYVLIGILSLFVLSNLVYAITQDYTTMMIFRILPALMHAVFFSVALVAATSMVP 124
Query: 153 EAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
E+S A V A LV + A+L + Y + +M + ES
Sbjct: 125 AEEQSNAAAKVFGGVAVGLVFGIPISAFLAEQYSLAYAFYFGLTACAIALVSVMFLM-ES 183
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
P K + + V + +L TV+ + A+F S YS I YL
Sbjct: 184 APVKEKMSFGSQVTILRSKSMWLSL------STVIFVFAAMFSS-------YSFITQYLS 230
Query: 273 LVMGFGVVQVAIFIAIVGVLSIGVQVILGFL----MKSLGAKHTIMVGLLFEMLQLMWYG 328
V ++ + + GV I I G L MK + +++GL+F + M +
Sbjct: 231 TVTNMNGTWISAMLMVFGVFGIFGNFIFGKLLGKNMKKTVMLYPVILGLIFVTVYFMGFS 290
Query: 329 FGSRTWMMWAAGVLAALGSI 348
F M+ G + + G +
Sbjct: 291 FSFMVAMVAFWGAVHSAGLV 310
>UniRef50_Q869U5 Cluster: Similar to Xanthomonas campestris (Pv.
campestris). Tetracycline- efflux transporter; n=2;
Dictyostelium discoideum|Rep: Similar to Xanthomonas
campestris (Pv. campestris). Tetracycline- efflux
transporter - Dictyostelium discoideum (Slime mold)
Length = 473
Score = 54.0 bits (124), Expect = 8e-06
Identities = 66/313 (21%), Positives = 122/313 (38%), Gaps = 20/313 (6%)
Query: 80 IKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVT 139
+ + F+ PL+G LSD + + F I + T N +++ ++ G+ V
Sbjct: 101 LPNLTMFIFGPLVGVLSD---SSIMDMASCF-----ISMYTHNLAYYYVFHTLGGINVVM 152
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXX 199
VF+Y+AD+ E Y A+ +VI P + ++ L G
Sbjct: 153 QPAVFSYIADIFDEDHVPILYSFAGASLGIGVVIGPLIFVFISSL-GSQFIPLYVTGGLM 211
Query: 200 XXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLP 259
F + +PESL IS +PF + + + V VF S +
Sbjct: 212 SLCFIGIPFLPESLEIAKENNRIQETIS--TFNPFKLIYNLLKSSGYIFWVVLVFAS-IN 268
Query: 260 EAGQ--YSCIFVYLKLVMGFGVVQVAIFIAIVG-VLSIGVQVILGFLMKSLGAKHTIMVG 316
GQ + +++ L+ +G Q ++A +G + I ++ L+K L + I +G
Sbjct: 269 YTGQDLINDYYLFASLLYDWGPTQNGYYLAALGTTIVIWGAFVIPLLLKYLSQRRVITIG 328
Query: 317 LLFEMLQLMWYGFG----SRTWMMWAAG-VLAALGSITYPAISAYVSVNSRADRQGVVQG 371
+L + + F ++++ G + I A +S + A+ QG V
Sbjct: 329 YCCSLLAHVMFVFAGIKVKYNFVIFLVGSIFVGFVPNNMNIIQAVISGCTPANLQGSVLT 388
Query: 372 MVTGVRGLCNGLG 384
+ GL N +G
Sbjct: 389 GANAIAGLANFVG 401
>UniRef50_A7SUG3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 259
Score = 54.0 bits (124), Expect = 8e-06
Identities = 45/193 (23%), Positives = 85/193 (44%), Gaps = 3/193 (1%)
Query: 203 FFIMVAVPESLPEKVR-PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEA 261
F+++V +PES P+ R P S++ A + G R++ +L + L L
Sbjct: 49 FYVVVLLPESTPKTKREPCRLLSCDSFKVIWSVYADPRNGYRRSLFLLLIGDGLVSLATM 108
Query: 262 GQYSCIFVY-LKLVMGFGVVQVAIFIAIVGVLS-IGVQVILGFLMKSLGAKHTIMVGLLF 319
G I ++ L+ + + F+A + IG V +G + L + VGL+
Sbjct: 109 GLSGVISLFVLRSPLCWSPTYFGGFMAFRFLTQGIGGIVGIGIFKRFLSDSNIARVGLIS 168
Query: 320 EMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGL 379
+ L+ + F S+TW+++ ++ L P + ++ +R D +G V +
Sbjct: 169 LIASLVVFAFASKTWVVFLVPIVGLLTGTISPIMKGMITQLTRPDERGAAFSAVAAISTF 228
Query: 380 CNGLGPAMFGVIF 392
CN LG +F I+
Sbjct: 229 CNFLGAFVFNPIY 241
>UniRef50_A7I7E2 Cluster: Major facilitator superfamily MFS_1; n=1;
Candidatus Methanoregula boonei 6A8|Rep: Major
facilitator superfamily MFS_1 - Methanoregula boonei
(strain 6A8)
Length = 407
Score = 54.0 bits (124), Expect = 8e-06
Identities = 75/372 (20%), Positives = 148/372 (39%), Gaps = 21/372 (5%)
Query: 33 GEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLI 92
G +++ ++ F F+ + P++ + + L+ G+I + + L + +
Sbjct: 14 GRVLMYYLCLIGFFAIFSTTISKSPVLPLFVQSLGAGPALL-GVIAAVSPLAGVLFSFPV 72
Query: 93 GALSDVWGRKFFLLVTVF-FTCAPIPLMTI-NTWWFFAMISISGVF-AVTFSIVFAYVAD 149
G LSD GR+ L+++ F F API + I + W + G A+ +V A +A+
Sbjct: 73 GVLSDHLGRRRLLVISAFVFLIAPILYLFITDPVWLVPVRFFHGTATAILGPVVSAIIAE 132
Query: 150 VTTEAERSRAYGLVSATFAASLVISPALGAYLMD--LYGESLXXXXX----XXXXXXXXF 203
++ + SAT ++P G ++ L+ L F
Sbjct: 133 RFPDSRGEKLGTYASATLVGR-TLAPLAGGIIITAFLFAPGLLAYRMVYICAALSALPVF 191
Query: 204 FIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQ 263
+++ E+ + G G + E F R++ R M +A + +Y G
Sbjct: 192 VLILRYREAEAGSLVLPGIG--VYKESLATFVTNRRL---RATAMADMASYFAY----GV 242
Query: 264 YSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQ 323
+ + F Q I A+ ++ G + + G L + + I+ GLL +
Sbjct: 243 FETFLPLYLASLSFAAYQTGIIFAVQVLIIAGTKPVFGRLSDRIDRRIQIVTGLLVTGIA 302
Query: 324 LMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNG 382
+ S AA L LG +++ A SAYV+ ++ ++ G G ++ + +
Sbjct: 303 IAAVPVASTFPGFLAASALFGLGIAVSTVATSAYVADVAKQEQIGSSMGALSSIMDIGQS 362
Query: 383 LGPAMFGVIFYL 394
GP + GV+ L
Sbjct: 363 SGPLITGVVITL 374
>UniRef50_A3H8V2 Cluster: Major facilitator superfamily MFS_1; n=1;
Caldivirga maquilingensis IC-167|Rep: Major facilitator
superfamily MFS_1 - Caldivirga maquilingensis IC-167
Length = 491
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
Query: 90 PLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYV 147
P++G L D++G+K L V + L +++ + A I G+ F++ F+ +
Sbjct: 68 PIVGRLGDIYGKKRVLSAVVIIYAVAVTLTSVSPSFTYLIAFRGIQGIGVTMFALAFSLI 127
Query: 148 ADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMV 207
+ RA GLVSA F I+ LGAY+ +G + I+
Sbjct: 128 REEFPRELIPRAQGLVSAAFGIGAAIALPLGAYISQYFGWRTTYHTAIPFVLLVAYLIVT 187
Query: 208 AVPES 212
+ ES
Sbjct: 188 RIKES 192
>UniRef50_Q8ZQ25 Cluster: Multidrug resistance protein mdtG; n=36;
Enterobacteriaceae|Rep: Multidrug resistance protein
mdtG - Salmonella typhimurium
Length = 404
Score = 54.0 bits (124), Expect = 8e-06
Identities = 71/326 (21%), Positives = 125/326 (38%), Gaps = 15/326 (4%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAM 129
+ +GL+ I + S +++P G L+D GRK LL + + LM + N W F +
Sbjct: 52 MWSGLVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMAIVMLLMGMAQNIWQFLIL 111
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
++ G+ A +A + A G +S + ++ P G L D YG L
Sbjct: 112 RALLGLLGGFIPNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAGGLLADHYG--L 169
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLML 249
F++ + E P ++ + A+L+ R VL L
Sbjct: 170 RPVFFITASVLFICFLLTFF--FIRENFLPVSKKEMLHVREV--VASLKN---PRLVLSL 222
Query: 250 CVAVFLSYLPEAGQYSCIFVYLKLVMG--FGVVQVAIFIAIV-GVLSIGVQVILGFLMKS 306
V + + + +Y++ + G + ++ IA V GV ++ LG L
Sbjct: 223 FVTTLIIQVATGSIAPILTLYVRELAGDVSNIAFISGMIASVPGVAALLSAPRLGKLGDR 282
Query: 307 LGAKHTIMVGLLFEMLQLMWYGFGSRTWMM-WAAGVLAALGSITYPAISAYVSVNSRADR 365
+G + ++V L+ +L L+ F W + +L A PA+ + NS
Sbjct: 283 IGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLLVYNSTNQI 342
Query: 366 QGVVQGMVTGVRGLCNGLGPAMFGVI 391
G + R + N GP M I
Sbjct: 343 AGRIFSYNQSFRDIGNVTGPLMGAAI 368
>UniRef50_UPI0000499030 Cluster: major facilitator superfamily
protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: major
facilitator superfamily protein - Entamoeba histolytica
HM-1:IMSS
Length = 531
Score = 53.6 bits (123), Expect = 1e-05
Identities = 42/159 (26%), Positives = 76/159 (47%), Gaps = 6/159 (3%)
Query: 31 GIGEPSVFHALVVIFLEFFAWGLLTMP----IISVLNATFPDHTFLMNGLIMGIKGILSF 86
GI + +F L+++ +E + +L I+ + + + +G ++ I F
Sbjct: 23 GIPKKKLFPLLLMLLIEGISQNILNAYVGYLIVDMGTVSSLNEVGNYSGWLISSFSIAQF 82
Query: 87 LSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL--MTINTWWFFAMISISGVFAVTFSIVF 144
S+ +IGALSD GR+ L+V F L + N ++ AM ++G+ T IV
Sbjct: 83 TSSFIIGALSDNLGRRPMLMVGTFGIAISNILFGFSFNYYFVVAMRLLNGMLNGTVGIVK 142
Query: 145 AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
AY+ ++T ++ R +A+ T++ VI LG L D
Sbjct: 143 AYMGEITDDSNRVQAFSFNGLTWSIGSVIGSFLGGVLYD 181
>UniRef50_Q30UI0 Cluster: Major facilitator superfamily MFS_1; n=1;
Thiomicrospira denitrificans ATCC 33889|Rep: Major
facilitator superfamily MFS_1 - Thiomicrospira
denitrificans (strain ATCC 33889 / DSM 1351)
Length = 438
Score = 53.6 bits (123), Expect = 1e-05
Identities = 45/186 (24%), Positives = 77/186 (41%), Gaps = 6/186 (3%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
VF ++ L F L +P+IS+ T + G+++G + + G++S
Sbjct: 5 VFPLSAILSLRFLGL-FLVLPVISIYALELKGSTPFLVGIVVGGYALTQAIFQVPFGSMS 63
Query: 97 DVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEA 154
D GRK LLV + L +T + MI + G A+ S++ A ++D+ E
Sbjct: 64 DKIGRKPTLLVGLLIFLVGSVLCAYSTDIYTLMIGRFLQGAGAIG-SVITAMISDLVQEE 122
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLP 214
R +A ++ A+ A S ++ LG L YG + VP P
Sbjct: 123 IRGKAMAIMGASIALSFALAMGLGPVLGAKYGVEFLFILTALFAVLAIILLFTKVP--TP 180
Query: 215 EKVRPT 220
K++ T
Sbjct: 181 PKIKHT 186
Score = 34.7 bits (76), Expect = 5.4
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 6/132 (4%)
Query: 267 IFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
I +Y + G V I + + QV G + +G K T++VGLL ++ +
Sbjct: 26 ISIYALELKGSTPFLVGIVVGGYALTQAIFQVPFGSMSDKIGRKPTLLVGLLIFLVGSVL 85
Query: 327 YGFGSRTWMMWAAGVL---AALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGL 383
+ + + + L A+GS+ IS V R ++ + L GL
Sbjct: 86 CAYSTDIYTLMIGRFLQGAGAIGSVITAMISDLVQEEIRGKAMAIMGASIALSFALAMGL 145
Query: 384 GP---AMFGVIF 392
GP A +GV F
Sbjct: 146 GPVLGAKYGVEF 157
>UniRef50_Q0S8F1 Cluster: Multidrug transporter, MFS superfamily
protein; n=5; Actinomycetales|Rep: Multidrug
transporter, MFS superfamily protein - Rhodococcus sp.
(strain RHA1)
Length = 552
Score = 53.6 bits (123), Expect = 1e-05
Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 83 ILSFLSAPLIGALSDVWGRK--FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAV-T 139
+ + L+ PL G LSD++GRK F +TVF + + + + + A ++ G+ A
Sbjct: 63 VTATLATPLYGKLSDIYGRKPFFMFAITVFVIGSVMCTFSTSMYMLAAFRAVQGLGAGGL 122
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALG 178
FS+ + D+ + ER++ G A F S V+ P LG
Sbjct: 123 FSLALTIIGDIVSPRERAKYQGYFLAVFGTSSVLGPVLG 161
>UniRef50_Q17KH4 Cluster: Adenylate cyclase, putative; n=1; Aedes
aegypti|Rep: Adenylate cyclase, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 412
Score = 53.6 bits (123), Expect = 1e-05
Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 13/140 (9%)
Query: 57 PIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVT---VFFTC 113
P++ + A +N +I+ IK ++ A L+GA SD +GRK +++T +F T
Sbjct: 151 PVVQEIEAQVKPVAASVNTVIVAIKSVIPVFGALLLGAWSDRYGRKPVVVITGCGLFVTY 210
Query: 114 API-------PLMTINTWWF---FAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLV 163
+ + +N W++ F SI+G A+ + ++A+++D++ + R+ G +
Sbjct: 211 VALTGLNYLSSFVQVNLWFYAIAFIPFSITGGIAILVATIYAFISDISNDQIRTIKMGFM 270
Query: 164 SATFAASLVISPALGAYLMD 183
SA A + Y+++
Sbjct: 271 SAVMVAGAALGSFSCRYILE 290
>UniRef50_Q2FLU6 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Methanospirillum hungatei JF-1|Rep:
Major facilitator superfamily MFS_1 precursor -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 461
Score = 53.6 bits (123), Expect = 1e-05
Identities = 35/100 (35%), Positives = 54/100 (54%), Gaps = 9/100 (9%)
Query: 93 GALSDVWGRK-FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVF-----AVTFSIVFAY 146
G L+D++GRK F++ T+ F + L I+ W ++I I+ + A+ FS A
Sbjct: 65 GKLADIYGRKRVFIIGTILFAIGSL-LAAIS--WSGSVIIIARMIQGLGGAMVFSTSMAI 121
Query: 147 VADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
V V ER RA G+++AT A L + P LG +L +YG
Sbjct: 122 VTVVFPPGERGRAIGIITATVYAGLSLGPVLGGFLTQMYG 161
>UniRef50_Q12IY6 Cluster: Major facilitator superfamily MFS_1; n=11;
Alteromonadales|Rep: Major facilitator superfamily MFS_1
- Shewanella denitrificans (strain OS217 / ATCC BAA-1090
/ DSM 15013)
Length = 455
Score = 53.2 bits (122), Expect = 1e-05
Identities = 74/330 (22%), Positives = 136/330 (41%), Gaps = 25/330 (7%)
Query: 27 MTMSGIG--EPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGIL 84
MT G+ E V +L +F + MPI ++ + L G+ +G G+
Sbjct: 1 MTNHGLSSLEKKVAFSLAGVFGLRMMGLFMIMPIFALYGQHLEGFSPLWVGIAIGAYGLT 60
Query: 85 SFLSAPLIGALSDVWGRKFFLLV--TVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSI 142
L +G LSD +GRK +L+ +F + I M+ + +W ++ G+ A+ +
Sbjct: 61 QALLQIPMGILSDKYGRKPIILIGLVLFAVGSIIAAMSDHIYWVVFGRAVQGMGAIA-AA 119
Query: 143 VFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXX 202
V A AD+T + +R++ ++ S +S G + G S
Sbjct: 120 VLALAADLTRDEQRTKVMAIIGMCIGLSFALSLLAGPLVAQYLGLSGIFWLTAVLAVLGM 179
Query: 203 FFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAG 262
+ VP + + + G + A P A LR++ + + L +F+ +L
Sbjct: 180 AIVHFLVPNPISQAPK----GDTL----AAP-AKLRRMLLDPQLFRLDAGIFILHL---- 226
Query: 263 QYSCIFVYLKL-VMGFGVVQ----VAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGL 317
+ +FV L ++ G+V+ + F A V + V +I+ +K K + L
Sbjct: 227 VLTAVFVALPFNLVDAGLVKEQHWLLYFPAFVAAFVLMVPMII-IGVKRNNTKTMFQLSL 285
Query: 318 LFEMLQLMWYG-FGSRTWMMWAAGVLAALG 346
+ ML L+ G + W++ AA VL G
Sbjct: 286 VIMMLSLLLMGLYAQNLWLLSAAVVLFFTG 315
>UniRef50_Q0RV66 Cluster: Multidrug resistance transporter, MFS
superfamily; n=2; Rhodococcus sp. RHA1|Rep: Multidrug
resistance transporter, MFS superfamily - Rhodococcus
sp. (strain RHA1)
Length = 408
Score = 53.2 bits (122), Expect = 1e-05
Identities = 56/230 (24%), Positives = 92/230 (40%), Gaps = 10/230 (4%)
Query: 91 LIGALSDVWGRKFFLL-VTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVF--AYV 147
L GALSD WGR+ LL +V FT A T + + F+ +V A +
Sbjct: 62 LAGALSDSWGRRRLLLGGSVAFTVASAVCALAPTIGVLTVARLIAGFSGGIGVVLARAVI 121
Query: 148 ADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMV 207
+D E +R + ++ + VI+P LG L+ G F +
Sbjct: 122 SDRARGIEAARLFSVMMIIGGVAPVIAPVLGGMLLGPIGWRGTFWVLTAIGGIMTFGVAT 181
Query: 208 AVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCI 267
A+PE+LP + R TG V+ R VG + + A+F SY+ +
Sbjct: 182 AIPETLPPETRHTGGLLVLGQNFRQVVGDRRFVGYAAAMAIGAGAMF-SYIAASP----- 235
Query: 268 FVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGL 317
FV K + GF Q ++ A + + I L+ + + ++ G+
Sbjct: 236 FVVQK-IFGFTPTQFSLVFAFNALSLVTAMTINSRLVSRISVRRLLIFGV 284
>UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC,
isoform C; n=2; Endopterygota|Rep: PREDICTED: similar to
CG32158-PC, isoform C - Tribolium castaneum
Length = 478
Score = 52.8 bits (121), Expect = 2e-05
Identities = 57/301 (18%), Positives = 125/301 (41%), Gaps = 25/301 (8%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLV----TVFFTCAPIPLMTINTWWFFAMI-------S 131
++ + A +GA SD GRK LL+ ++++ + T +TW ++ +
Sbjct: 91 VVPIILALFMGAWSDKRGRKLPLLIGLTGKLYYSVMVVVNATQDTWPVEYIVYTATLPMA 150
Query: 132 ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLY---GES 188
+G F+ F Y+ D++T+ R+ L+ + A++ ALG L + +
Sbjct: 151 FTGADVAIFAAAFTYLVDISTQESRTMRVTLLEVCYLATMPTGIALGKVLFNQVVNKSYA 210
Query: 189 LXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWE------QADPFAALRKV-- 240
+ + + + + +P P + + D L K
Sbjct: 211 VMFGINVALLFLAIVYSFLRLDWRTNSRQQPLSEAPNLFTDFFDYNHVVDTGKTLFKSRR 270
Query: 241 GAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLS-IGVQVI 299
+R L++ +A+ Y + + + ++Y++L+ + + + F + + + +
Sbjct: 271 NNQRCYLLILIAMMAFYTFQRDEKAMSYLYVQLIFKWTFDEFSNFRTVQSAIQDVFLLCA 330
Query: 300 LGFLMKSLGAKHTI--MVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYV 357
+ + + LG + TI M+G L + +++ +WM + GV AA+G I P I + V
Sbjct: 331 IPLMSRVLGWRDTIIIMIGALAHSVGRIFFATADESWMFYLGGVFAAIGPIVAPVIRSMV 390
Query: 358 S 358
S
Sbjct: 391 S 391
>UniRef50_UPI0000499E89 Cluster: major facilitator superfamily
protein; n=2; Entamoeba histolytica HM-1:IMSS|Rep: major
facilitator superfamily protein - Entamoeba histolytica
HM-1:IMSS
Length = 528
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
Query: 67 PDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLM--TINTW 124
P +G++ FLS+ +G LSD GR+ LL+ + L + N W
Sbjct: 59 PSQAGYYSGILNACYFFSQFLSSFFLGVLSDNIGRRPILLIGSLGSLISTLLFGFSFNYW 118
Query: 125 WFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL 181
W SI+G+ ++ ++ + +T+ R++ +GL+ T ++I ++G YL
Sbjct: 119 WAVISRSINGLVNGNIGVIKTFMGEFSTKENRAQVFGLIGLTNGLGMIIGASVGGYL 175
>UniRef50_Q3E4I1 Cluster: Drug resistance transporter EmrB/QacA
subfamily; n=2; Chloroflexus|Rep: Drug resistance
transporter EmrB/QacA subfamily - Chloroflexus
aurantiacus J-10-fl
Length = 625
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFAVTF 140
+ S P+ G LSD++GRK+ LL + VF + + + + + G A
Sbjct: 77 LASTAMVPIYGKLSDIYGRKYVLLFGIVVFLLGSLLCGLAADMTQLVVFRGLQGFGAAAL 136
Query: 141 -SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
S FA AD+ AER+R GL A F S V+ P +G L D
Sbjct: 137 TSTAFAIPADLFAPAERARYMGLFGAVFGLSSVVGPFIGGLLTD 180
>UniRef50_A7ICD9 Cluster: Major facilitator superfamily MFS_1; n=1;
Xanthobacter autotrophicus Py2|Rep: Major facilitator
superfamily MFS_1 - Xanthobacter sp. (strain Py2)
Length = 403
Score = 52.8 bits (121), Expect = 2e-05
Identities = 70/346 (20%), Positives = 136/346 (39%), Gaps = 23/346 (6%)
Query: 58 IISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLL-----VTVFFT 112
++ + +A+ P F+ +GL++ +L AP++G LSD WGR+ LL V +
Sbjct: 32 LVFLPDASLPLRNFV-SGLLVATYVLLMLYMAPVLGRLSDQWGRRPVLLLCGAGVLLGNL 90
Query: 113 CAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLV 172
A + + F I G A A + D + R +Y ++ ++ V
Sbjct: 91 LAGLAIDLHLLPLLFLGRFIGGATAAAQPTAQAALVDTGSNKARLLSYSMLFSSLG--FV 148
Query: 173 ISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQAD 232
+ P + + L +L +V + E+ +P G + W
Sbjct: 149 LGPVVASGL-----STLSFSAPLHLCTALTLVALVLLWTGYREEEKP---GRKVDWSTIS 200
Query: 233 PFAALR---KVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF--GVVQVAIFIA 287
F +R + ++ V + L + + + VYL G + QV F++
Sbjct: 201 IFEGVRCFREAAGDKAVRGILGGFLLMQVAWGSFFVFVSVYLMAAPGLRLSLHQVGAFMS 260
Query: 288 IVGV-LSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG 346
I+G+ I ++ L + G + + GL ++ + +AA ++A +
Sbjct: 261 IMGIGFCISNALVQPALSERFGMRSLAVAGLALNATTMVACLLLGSAYQAYAAALIAGIT 320
Query: 347 -SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+I YP+I +S +RQG + GMV + G+ + G +
Sbjct: 321 VNIAYPSIVTMLSDRVAPERQGWILGMVGSAAAMGWGISSVVSGAL 366
>UniRef50_A0UZW0 Cluster: Drug resistance transporter, EmrB/QacA
subfamily precursor; n=1; Clostridium cellulolyticum
H10|Rep: Drug resistance transporter, EmrB/QacA
subfamily precursor - Clostridium cellulolyticum H10
Length = 531
Score = 52.8 bits (121), Expect = 2e-05
Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFA-VT 139
+ S +S + G LSD++GRK FLL + +F + + ++ N + A I G+ +
Sbjct: 56 LTSTISTVIFGKLSDIYGRKIFLLSGIIIFLIGSFLTGLSANIFQMIAFRGIQGIGGGIL 115
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
SI V D+ ER++ G++ + F S ++ P LG ++D
Sbjct: 116 MSISLTAVGDLYPPQERAKWTGVMMSIFGISSILGPVLGGVMVD 159
>UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 606
Score = 52.8 bits (121), Expect = 2e-05
Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 17/161 (10%)
Query: 70 TFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVT---------VFFTCAPIPLMT 120
TF+M + I G+LS + P IG+LSD +GRK L+V V P T
Sbjct: 141 TFMMTMNL--ITGLLSAFTVPKIGSLSDRYGRKRLLVVASAGGIIGELVVILAVKFP-ET 197
Query: 121 INTWWFF---AMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPAL 177
++ W A+ + G F + +YV+D T +R A G + + A L P L
Sbjct: 198 VHLNWLLVAAALDGLGGSFTAASVVGHSYVSDCTPPRKRGVAIGYLHSALYAGLAFGPVL 257
Query: 178 GAYLMDLYGESLXXXXXXXXXXXXXFFIMV--AVPESLPEK 216
Y+++ L F +++ VPES+ +K
Sbjct: 258 AGYMVEKLTHELVSVFYVTLGCHLCFVVLILSIVPESVSQK 298
>UniRef50_Q8YRR2 Cluster: Alr3381 protein; n=2; Nostocaceae|Rep:
Alr3381 protein - Anabaena sp. (strain PCC 7120)
Length = 369
Score = 52.4 bits (120), Expect = 3e-05
Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWWFFAMISI- 132
G++MG I + P++G L+D GRK LL+ T+ T AP + + ++ +
Sbjct: 9 GIVMGGFAIGLLVFRPMLGRLADQNGRKLLLLIGTIVATTAPFGYLAFKSIPLLMLVRVF 68
Query: 133 SGVFAVTFSIVF-AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
GV F+ + A +AD+ A R +S T L I PALG YL G
Sbjct: 69 HGVSIAAFTTGYSALIADLAPMAIRGEIISYMSLTAPLGLAIGPALGGYLQASIG 123
>UniRef50_Q1AYE3 Cluster: Drug resistance transporter EmrB/QacA
subfamily precursor; n=1; Rubrobacter xylanophilus DSM
9941|Rep: Drug resistance transporter EmrB/QacA
subfamily precursor - Rubrobacter xylanophilus (strain
DSM 9941 / NBRC 16129)
Length = 607
Score = 52.4 bits (120), Expect = 3e-05
Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGV-FAVT 139
+ S ++ P++G LSD++GR+ F + + VF + + WW A ++ G+
Sbjct: 54 LASAVTVPVVGKLSDMYGRRGFFIWGLVVFMAGSALSGAAQGFWWLVAARAVQGLGMGTI 113
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
+ + D+ + ER R G + A F + + P +G ++ D
Sbjct: 114 MPLAQTIIGDIISPRERGRYVGYLGAVFGVASITGPLVGGWITD 157
>UniRef50_A4JV49 Cluster: Major facilitator superfamily MFS_1; n=2;
Proteobacteria|Rep: Major facilitator superfamily MFS_1
- Burkholderia vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 441
Score = 52.4 bits (120), Expect = 3e-05
Identities = 69/326 (21%), Positives = 125/326 (38%), Gaps = 14/326 (4%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISI 132
GL+ G + FL APL G +D GR+ +L+ + A + L + + + ++
Sbjct: 57 GLLTGTYALALFLFAPLWGRFADRRGRRPAILLGLVGFAATLALFALVSSLPLLYLERAL 116
Query: 133 SGVFAVTFS-IVFAYVADVTTEAE-RSRAYGLVSATFAASLVISPALGAYLMDLYGESLX 190
G+FA + + V+A V D E R+ + L++ A ++ P LG+ M + L
Sbjct: 117 GGLFASSIAPAVYALVGDHAPSKEWRAHRFALLNIAGATGFLVGPMLGSLTMHVARNFL- 175
Query: 191 XXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWG--PVISWEQADPFAALRKVGAERTVLM 248
++ V L V W P + DP + T+L
Sbjct: 176 ----PRAGETGTYWPPFLVTSGLAFAVALAVWAFVPSANGRAGDPHVSGGSPDGHATLLR 231
Query: 249 LCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSL 307
L V F++ + + V+G ++ + ++ + VQ ++ L+K
Sbjct: 232 LLVISFVTAAAVGTFEVGLSLRGTQVLGMNTAEIGLMFTECSLVMLTVQSLVFSPLVKPE 291
Query: 308 GAKHTIMVGLLFEMLQLMWYGF-GSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQ 366
+ + L L F S M A ++A I P + ++S+ + +RQ
Sbjct: 292 ATRWLLTPALAMLAASLAVVPFAASGLAMAIAVALVAGSAGIISPIATYWISLRA-GERQ 350
Query: 367 GVVQGMVTGVRGLCNGLGPAMFGVIF 392
G G T L +G GV+F
Sbjct: 351 GAALGWQTAAASLGQSVGSVSGGVLF 376
>UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 509
Score = 52.4 bits (120), Expect = 3e-05
Identities = 78/326 (23%), Positives = 131/326 (40%), Gaps = 27/326 (8%)
Query: 87 LSAPLIGALSDVWGRKFFLLVTVF--FTCAPIPLMTINTWW-FFAMI------SISGVFA 137
L+A L+G SD GRK +L+ F A + L T+ T + +I + G +
Sbjct: 98 LTACLLGTWSDKNGRKPLMLIVAFGAIVDASVALFTVYTDGPLYPLIIGGGINGVMGFYP 157
Query: 138 VTFSIVFAYVADVTTEAERSRAYGLVSA-TFAASLVISPALGAYLMDLYGESLXXXXXXX 196
+ AY+AD T R+ ++ A F + + + G Y+ L G
Sbjct: 158 TMVLALLAYIADTTPSKRRAIKLAVLEALAFLSGTLGHFSSGIYIHHL-GYKATFWGILS 216
Query: 197 XXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADP-FAALRKVGAERTVLMLCVAVFL 255
+++ +PES+P K R G ++ EQ + K R +L CV L
Sbjct: 217 LHLINFIYLLFFLPESMP-KQRIEQSGKCLTLEQVKSVYMVYLKKRDGRWIL--CVLSLL 273
Query: 256 SYLPEAGQYSCIFVYLKLVMG------FGVVQVAIFIA-IVGVLSIG--VQVILGFLMKS 306
S QY I L ++ G + V F+ ++ V + G + + LG LMK
Sbjct: 274 SVFFLFAQY--IVTTLGVLYGKRYPLCWSAELVGYFLGTLLCVKAFGAVLGIWLGSLMK- 330
Query: 307 LGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQ 366
L +G LF + L GF T++M+ + V + P I A +S + Q
Sbjct: 331 LTNYTAAQIGTLFLIAGLTMIGFSQTTFLMFMSCVANLFSGVPQPCIRAQMSQMVGKEEQ 390
Query: 367 GVVQGMVTGVRGLCNGLGPAMFGVIF 392
G + ++ + L N +F ++
Sbjct: 391 GALFAILASLESLTNFTSQLIFNPLY 416
>UniRef50_Q5KJI9 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 474
Score = 52.4 bits (120), Expect = 3e-05
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Query: 72 LMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS 131
L+ G++ + + +P +G L+D +GRK L+ T+ + +T + ++S
Sbjct: 86 LLGGMMGSLFSFCQCIISPWLGRLADKYGRKKVLIATMVGNVVSASIWIKSTSFESYLLS 145
Query: 132 --ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAY 180
+ G+ + A ++DVTT A RS++ LV F+ P+LGAY
Sbjct: 146 RLVGGLSEGNVQLSTAIISDVTTSATRSKSLALVGIAFSICFTFGPSLGAY 196
>UniRef50_UPI0000E48DE8 Cluster: PREDICTED: similar to MGC80576
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC80576 protein -
Strongylocentrotus purpuratus
Length = 462
Score = 52.0 bits (119), Expect = 3e-05
Identities = 73/354 (20%), Positives = 143/354 (40%), Gaps = 22/354 (6%)
Query: 56 MPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVT-----VF 110
M I S + L + + + + L+GA SD GRK L+V V+
Sbjct: 89 MTINSTMEMDIEQQVSLFSLYLSATTSVPALFCTTLLGAHSDQAGRKVALIVPSIGFCVY 148
Query: 111 FTCAPIPLM-TINTWWFFA---MISISGVFAVTFSIVFAYVADVTTEAERS-RAYGLVSA 165
C I M +N W+ ++ + G F++ + F+Y+AD+TT+ ER+ R L
Sbjct: 149 AACYLIVTMHELNIWYLVIGHFVLGLCGDFSLLLAGCFSYMADITTKKERALRIILLDCL 208
Query: 166 TFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPV 225
+F A+ + +G Y + G +++ VP++ P+ P V
Sbjct: 209 SFMAAGIAQVGVG-YWIHAQGFEAPYIFILACVSLTTVYVIFLVPDTHPQ-AHP---AMV 263
Query: 226 ISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMG----FGVVQ 281
+ L + + L L +A + L +S + L MG + +
Sbjct: 264 NVRDAIRKILNLVQSNTHKRRLPLLIATIVMLLRVLVFFSLPGLTLLYGMGDPFCWDSIV 323
Query: 282 VAIFIAIVGVLSIGVQVILG--FLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAA 339
+ IF A+ LS + +I+G L + L + VGL+ ++ ++ G ++A
Sbjct: 324 IGIFSAL-QYLSGALGMIIGGKLLSRYLRDATLVQVGLISSIMCVVLTGVAPSNPYIFAV 382
Query: 340 GVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
+ +++ P + +S QGV+ + ++ + + P +F ++Y
Sbjct: 383 PAVGLFRALSLPMLRTIMSKLVYPSEQGVMFACIGCLQSIAMVISPLIFNTLYY 436
>UniRef50_Q9RXQ1 Cluster: Multidrug-efflux transporter, putative;
n=2; Deinococcus|Rep: Multidrug-efflux transporter,
putative - Deinococcus radiodurans
Length = 544
Score = 51.6 bits (118), Expect = 4e-05
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Query: 87 LSAPLIGALSDVWGRK-FFLLVTVFFTCAPIPLMTINTW-WFFAMISISGVFAVT-FSIV 143
++ P++G LSD +GR+ LL V F + L + + A+ +I G+ T ++
Sbjct: 71 VTIPIVGTLSDRYGRRPLILLGIVVFALGSMGLGFVQSMEQLIALRAIQGIGGGTLMAMS 130
Query: 144 FAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
F +AD+ T ER R G A + S V+ P +G +L D +G
Sbjct: 131 FTAIADLFTPIERGRYQGYTGAVWGISSVVGPLVGGFLTDHFG 173
>UniRef50_Q2B8D0 Cluster: Major facilitator family transporter; n=1;
Bacillus sp. NRRL B-14911|Rep: Major facilitator family
transporter - Bacillus sp. NRRL B-14911
Length = 532
Score = 51.6 bits (118), Expect = 4e-05
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWWFFAMISISGV----FA 137
+ S ++ L+G LSD++GRK F+L+ + F+ T + F +I+ G+
Sbjct: 56 LTSAITTILVGKLSDIYGRKPFILIGIIIFSIGAFLSGTSSD--IFDLITYRGIQGFGAG 113
Query: 138 VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
+ S F V D+ ER + G +SA F S V P LG Y++D
Sbjct: 114 MIMSTAFTAVGDLFAPRERGKWQGAMSAVFGISSVFGPTLGGYIVD 159
>UniRef50_Q0S4G7 Cluster: Multidrug transporter, MFS superfamily
protein; n=1; Rhodococcus sp. RHA1|Rep: Multidrug
transporter, MFS superfamily protein - Rhodococcus sp.
(strain RHA1)
Length = 513
Score = 51.2 bits (117), Expect = 6e-05
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 2/140 (1%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVT--VFFTCAPIPLMTINTWWFFAMISI 132
G ++ I ++ S PL+G L D++G+K +LV+ VF + + + N F +
Sbjct: 82 GWVITIVTLMLAASTPLVGKLGDIYGKKRMMLVSAAVFGVGSLLGALAPNFELFLVGRGL 141
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXX 192
G + + + D+ + A G V+ AS ++ P +G YL+D +G +
Sbjct: 142 QGAGMAILVLAYGLIRDILPPSIIPVAVGFVATGMGASTILGPIIGGYLIDHFGYTGVFW 201
Query: 193 XXXXXXXXXXFFIMVAVPES 212
+ + VPE+
Sbjct: 202 AQLLHVAVVGIAVAIFVPET 221
>UniRef50_Q5AX13 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 521
Score = 51.2 bits (117), Expect = 6e-05
Identities = 41/180 (22%), Positives = 82/180 (45%), Gaps = 15/180 (8%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTV-FFT 112
+ +P++ +L A + T MN L++ + ++ ++ L+ +LSD+ GR+ + T+ +T
Sbjct: 66 IVLPVLPILQAEYGVTTTQMN-LLVTVFSLVQGITPALMSSLSDLQGRRIAWMFTLALYT 124
Query: 113 CAPIPLMTINTWWFFAMI----SISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFA 168
A I L +++ ++ S+ A+ F FA AD+++ AER R G + +
Sbjct: 125 VANIGLAAQDSYIALIVLRCLQSLGSSCAIPFG--FAVAADISSPAERGRYIGPLQGSVM 182
Query: 169 ASLVISPALGAYLMDLYG-ESLXXXXXXXXXXXXXFFIMVAVPESLPE-----KVRPTGW 222
+ P +G L +G S+ +I + +PE+ + P GW
Sbjct: 183 GAFAFGPVIGGLLAPSFGWRSIFWFLAIGSGAALLAYIFI-IPETARSIVGNGSIEPAGW 241
>UniRef50_Q0U5D5 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 594
Score = 51.2 bits (117), Expect = 6e-05
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 13/123 (10%)
Query: 71 FLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV----TVF-----FTCAPIPLMTI 121
FL+ G + GILS +++P +GALSD GRK FL+ T+F A P +
Sbjct: 166 FLLYGSLCS--GILSAITSPKLGALSDRHGRKKFLIFNTIGTLFAEVLTILAAKYPDIFH 223
Query: 122 NTWWF--FAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGA 179
W + + ++G F V +I +Y +D T+ +R+ A+ A + I PAL
Sbjct: 224 VNWILVGYCIEGVTGSFIVGMAIAHSYASDCTSPQKRTVAFSYFHACLFGGIAIGPALSG 283
Query: 180 YLM 182
Y++
Sbjct: 284 YVI 286
Score = 34.7 bits (76), Expect = 5.4
Identities = 18/80 (22%), Positives = 38/80 (47%)
Query: 313 IMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGM 372
I + F+M+ + + + + +G LAA+G I P + A ++ + D+ G + G
Sbjct: 465 IRAAIFFDMMGYLGFILARKGEIFALSGALAAMGGIGNPTLGAALTKHVPPDKVGQLLGA 524
Query: 373 VTGVRGLCNGLGPAMFGVIF 392
+ + +GP +F I+
Sbjct: 525 TGLLHAVARVIGPTIFNGIY 544
>UniRef50_Q4S0N3 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 437
Score = 50.8 bits (116), Expect = 8e-05
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT---WWFFAMIS 131
G++ GIL S+ ++G+ SDV GR++ LL + + L+ ++T + A I
Sbjct: 32 GIVGSTYGILQLFSSTVVGSWSDVVGRRYSLLTCLLSSALGYILLGMSTSIALFVLARIP 91
Query: 132 IS------GVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLY 185
+ G+F + SI A ++D+ E+ER G +A + ++ P +G YL +
Sbjct: 92 VGRFWTPGGLFKHSLSICRALLSDLVAESERPLVMGHFNAASSVGFILGPVVGGYLTEQE 151
Query: 186 G 186
G
Sbjct: 152 G 152
>UniRef50_Q62FE5 Cluster: Major facilitator family transporter;
n=39; Betaproteobacteria|Rep: Major facilitator family
transporter - Burkholderia mallei (Pseudomonas mallei)
Length = 385
Score = 50.8 bits (116), Expect = 8e-05
Identities = 75/291 (25%), Positives = 122/291 (41%), Gaps = 22/291 (7%)
Query: 40 ALVVIFLEFFAWGLLTMPIISVLNATFPD-HTFLMNGLIMGIKGILSFLSAPLIGALSDV 98
+L IF + MP+ SV T P ++ G+ +G G+ L G SD
Sbjct: 11 SLAAIFALRMLGLFMIMPVFSVYAKTIPGGENVVLVGIALGAYGVTQSLLYIFYGWASDK 70
Query: 99 WGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAER 156
+GRK + + +F + + + W I G+ AV+ S V A++AD+T+E R
Sbjct: 71 FGRKPVIAAGLLIFALGSFVAAFAHDITWIIVGRVIQGMGAVS-SAVLAFIADLTSEHNR 129
Query: 157 SRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEK 216
++A +V + S ++ + G S ++ VP++ P
Sbjct: 130 TKAMAMVGGSIGMSFAVAIVGAPIVFHWVGMSGLFAIVGALSVAAIGVVLWVVPDA-PRP 188
Query: 217 VR-PTGWGPVI-SWEQADPFAALRKVGAERTVLMLCVAVFL--SYLPEAGQYSCIFVYLK 272
V P + V+ + E + + A +T L L V L LP A + VYL
Sbjct: 189 VHVPAPFAEVLHNVELLRLNFGVLVLHATQTALFLVVPRLLVDGGLPVASHWQ---VYLP 245
Query: 273 LVMGFGVVQV--AIFIA-----IVGVLSIGVQVIL-GFLMKSLGAKHTIMV 315
VMG V + AI +A + VL G+ IL G L+ + A HTI++
Sbjct: 246 -VMGLAFVMMVPAIIVAEKQGRMKPVLLGGIAAILIGQLLLGV-ATHTILI 294
>UniRef50_Q3ZXW4 Cluster: Major facilitator family transporter; n=2;
Dehalococcoides|Rep: Major facilitator family
transporter - Dehalococcoides sp. (strain CBDB1)
Length = 423
Score = 50.8 bits (116), Expect = 8e-05
Identities = 68/346 (19%), Positives = 136/346 (39%), Gaps = 20/346 (5%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTC 113
L++P IS+ + GL++ + G +S + + GAL+D +GRK +L+T +
Sbjct: 43 LSLPFISLYLYQERGLSMTQVGLVILLSGFVSAIVQMVAGALADTYGRKPVMLLTTVGSA 102
Query: 114 APIPLMTINTWWFF-AMISISGVFAVTFSIVF------AYVADVTTEAERSRAYGLVSAT 166
M + + M+ I + ++V A +AD+T + + YG+V
Sbjct: 103 VIYGAMAVLIGFNMPVMLIILSYVLLRCTLVATRPASQAMIADLTPKDRLTETYGMVRIG 162
Query: 167 FAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVI 226
I P LG +L+ + + + ESL V W +
Sbjct: 163 NNLGWAIGPMLGGFLLIGLPYAYLFGVGAVVCLITLYITAKYINESLSNSVE---W---V 216
Query: 227 SWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFI 286
S + F+A G +R L + L ++ S + V+ + F + +
Sbjct: 217 SLTKI--FSA----GKDRAFLWFTILSILLFIVVGQFISTLSVFTVDRLHFSEADYGMLL 270
Query: 287 AIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG 346
+ G++ +Q + ++ ++ H +++G L + + + + + M + A + +G
Sbjct: 271 TLNGLMVFALQYPVTRILHNVSKSHMVVMGSLIYAVGYLMFAWTTNLGMAFLAMSVITMG 330
Query: 347 SITY-PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
I + P A V S ++G G L LGP + G +
Sbjct: 331 EIVFAPTTLAVVGDLSPPQQRGRYMGFYGFSEMLGFSLGPMVGGAL 376
>UniRef50_Q2S940 Cluster: Permease of the major facilitator
superfamily; n=2; Proteobacteria|Rep: Permease of the
major facilitator superfamily - Hahella chejuensis
(strain KCTC 2396)
Length = 460
Score = 50.8 bits (116), Expect = 8e-05
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK--FFLLVTVFF 111
+ +P+ VL T + GL +G+ G+ + GALSD +GRK F+ + VF
Sbjct: 31 MVLPVFMVLGRELEGATPALLGLAIGVYGLSQAVMQVPFGALSDRFGRKKLIFIGLGVFC 90
Query: 112 TCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASL 171
+ + ++ N + + G A+ S++ A ++D+T E R++A V T S
Sbjct: 91 LGSVVAALSDNIYGVIFGRLLQGAGAIA-SVLMALLSDLTQEENRTKAMASVGMTIGLSF 149
Query: 172 VISPALGAYLMDLYG 186
++ LG + G
Sbjct: 150 ALALVLGPLISGFAG 164
>UniRef50_Q2BPI0 Cluster: Probable NreB protein; n=1; Neptuniibacter
caesariensis|Rep: Probable NreB protein - Neptuniibacter
caesariensis
Length = 459
Score = 50.8 bits (116), Expect = 8e-05
Identities = 63/280 (22%), Positives = 116/280 (41%), Gaps = 15/280 (5%)
Query: 52 GLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFF 111
GL T+ + + P + G+ + IK + AP++G + RK +L
Sbjct: 27 GLTTVALALLAFDLNPGDAGWVLGIALAIKMVAYLCVAPVVGGYASQLPRKRWLAGLNIG 86
Query: 112 TCAPIPLMTIN--TWWFFAMISISGVFAVTFSIVF-AYVADVTT-EAERSRAYGLVSATF 167
+ LM + W F ++ + A ++ V+ A + DV E E +RA L
Sbjct: 87 RALLVALMPFSQDAWQLFLLMFLLNAMAAGYTPVYQALLPDVLPDEKEYTRALSLSRLAM 146
Query: 168 AASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVIS 227
++SPAL A+L+ G ++ F+++AV + R G +S
Sbjct: 147 EMESLLSPALAAFLLLFTGYAVLFELNALGFVIAALFLLLAVVPANSVSDRSGGVWKKVS 206
Query: 228 WEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCI--FVYLKLVMGFGVVQVAIF 285
+ + K + VL+L +A L AG + VY++ V+G QV +
Sbjct: 207 F----GIKSYLKTPRLKAVLLLNLA-----LSAAGAMIIVNSVVYVRAVLGLSEEQVPLL 257
Query: 286 IAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLM 325
+ GV S+ +L L++S+ + + +G +L L+
Sbjct: 258 MLSAGVGSMLAAFVLPKLLESVQDRPVMFLGAGLLVLALL 297
>UniRef50_Q83CB9 Cluster: Multidrug transporter, putative; n=5;
Coxiella burnetii|Rep: Multidrug transporter, putative -
Coxiella burnetii
Length = 412
Score = 50.4 bits (115), Expect = 1e-04
Identities = 75/362 (20%), Positives = 143/362 (39%), Gaps = 21/362 (5%)
Query: 36 SVFHALVVIFLEFFAWGLLTMPIIS---------VLNATF-PDHTFLMNGLIMGIKGILS 85
++F ++V+FL+ G++ PI+S VL AT P+ L G+++G+ +
Sbjct: 9 TLFSLMMVLFLDGMGQGIV-FPILSQALIDPQQHVLIATATPEMRNLWYGILIGVFFLCW 67
Query: 86 FLSAPLIGALSDVWGRKFFLLVTVFFT-----CAPIPLMTINTWWFFAMISISGVFAVTF 140
F+ A L+ LSD GRK L++ + + A + + W + G +
Sbjct: 68 FIGAALLSDLSDKSGRKKALIICLIGSLLGNFVAALAFTLHSLWLLLVGRMLVGFTNGSQ 127
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
I A V D++ + + SR G V + L+ P +G +L D
Sbjct: 128 PIAQAAVVDISPKNKLSRYLGYVIMAVSIGLIAGPLIGGFLSDHDYVRWFSYSTPLYFAA 187
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
F+ + + ++ T + +A +V L + L +
Sbjct: 188 LLAFVNILLLIIYFKETGITKEKTQLKLTRA--LEIFVSAFRHPSVRFLSICYLLLQIGW 245
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGV-LSIGVQVILG-FLMKSLGAKHTIMVGLL 318
+ Y I ++ + V+I A VGV L+ G+ V+ G F ++ KH + G
Sbjct: 246 SIYYIYISAFIVQKFNLSLRGVSILFAFVGVGLTFGLAVLPGIFEKQNFNRKHVTIFGYS 305
Query: 319 FEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVR 377
L L++ F ++ W G ++ Y + + S ++QG + G+ + +
Sbjct: 306 ILFLGLIFTVFPNKAIWPWIMIFPLTCGLALAYSFLISLYSNEVGPEKQGWIMGITSAIV 365
Query: 378 GL 379
L
Sbjct: 366 AL 367
>UniRef50_Q7M899 Cluster: MULTIDRUG-EFFLUX TRANSPORTER; n=2;
Helicobacteraceae|Rep: MULTIDRUG-EFFLUX TRANSPORTER -
Wolinella succinogenes
Length = 437
Score = 50.4 bits (115), Expect = 1e-04
Identities = 78/364 (21%), Positives = 148/364 (40%), Gaps = 28/364 (7%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
++ L FF + MP++S+ T ++ G+ +G + L G +SD GRK
Sbjct: 11 ILALRFFGL-FIVMPVLSLYALEMEGATPILMGIAIGGYALTQVLLQIPFGLVSDRIGRK 69
Query: 103 --FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAY 160
F + VF + + M + + G A+ +V A +AD+ E R++A
Sbjct: 70 KTIFFGLLVFVLGSVVCAMAESIEMLIVGRFLQGAGAIG-GVVSAMIADLVKEERRTKAM 128
Query: 161 GLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPT 220
++ AT + S + LG + +G + + VPE+
Sbjct: 129 AVMGATISMSFTAAMILGPIIGSSFGVDKLFWLTALLASLAILVLFINVPEA-------- 180
Query: 221 GWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF--- 277
P++S+ + ++V ++ + ++ + FL + + + L LV G
Sbjct: 181 ---PLVSYSFEAEESRWQEVLHDKNLQLMNLTNFLQ--KAFMTLAFLIIPLALVKGMHFE 235
Query: 278 --GVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSR-TW 334
+ +V I AI+GVLS+ IL K K ++ G++ M L + SR W
Sbjct: 236 HQDLWKVYIPAAILGVLSMAPAAILA--EKKGYFKGVLLFGIV--MFALSYTCMVSREPW 291
Query: 335 MMWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFY 393
+ +L +G S P + + S ++A ++G G+ T L + G + G +
Sbjct: 292 LFILGVMLFFIGFSAHEPIMQSLASKYAKAHQKGAALGVFTSFGYLGSFFGGLLGGHFYQ 351
Query: 394 LFHV 397
F +
Sbjct: 352 WFGI 355
>UniRef50_Q121X9 Cluster: Major facilitator superfamily MFS_1
precursor; n=3; Betaproteobacteria|Rep: Major
facilitator superfamily MFS_1 precursor - Polaromonas
sp. (strain JS666 / ATCC BAA-500)
Length = 393
Score = 50.4 bits (115), Expect = 1e-04
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Query: 26 IMTMSGIGEPSVFHALVVIFLEFFAWGLLTMP--IISVLNATFPDHTFLMNGLIMGIKGI 83
+MT S + V + F+ FA L MP +L + + + G +
Sbjct: 1 MMTPSPVPRAIVLAVMAGHFVAAFA--ALGMPPFFALILEQSLHNEARYLAGWFYVVPTA 58
Query: 84 LSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL--MTINTWWFFAMISISGVFAVTFS 141
+ LS+P G L+D +G+K L+ A L NTW FFA +++ GV TF+
Sbjct: 59 FAALSSPWWGRLADRYGKKRLLIRAQLGLAASFLLAGFATNTWVFFAALALQGVLGGTFA 118
Query: 142 IVFAYVADVTTEAERSRAYGLVSATFAASLVISP-ALGAYL 181
AY+A + + +R + + A+LV +P ALG L
Sbjct: 119 ASNAYLATIASGPALARGLTAMQWSARAALVAAPLALGLAL 159
>UniRef50_A1W636 Cluster: Major facilitator superfamily MFS_1; n=3;
Comamonadaceae|Rep: Major facilitator superfamily MFS_1
- Acidovorax sp. (strain JS42)
Length = 441
Score = 50.4 bits (115), Expect = 1e-04
Identities = 76/334 (22%), Positives = 129/334 (38%), Gaps = 21/334 (6%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWW----FFAM 129
GL+ G + APL G +SD GR+ LL+ V + + +PL+ W +A+
Sbjct: 65 GLLSGAYAAGVLVGAPLWGVVSDRVGRRRILLIGLVGYVLSLLPLLWPE-WTGLAGIYAL 123
Query: 130 ISISGVF-AVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGES 188
+G F A +V A VA+ T E +R+R + + A + P L A L +
Sbjct: 124 RVATGFFVAAVVPVVPALVAEYTPEDQRARRFAWLGAMSLLGFLFGPGLNAVAGRL-SSA 182
Query: 189 LXXXXXXXXXXXXXFFIMVAVPESLP----EKVRPTGWGPVISWEQADPFAALRKVGAER 244
L ++ A+ L P+G P + EQA ++
Sbjct: 183 LTDAGTGSYAATDLVILLAALLGGLMMLGLAASLPSGLAPTLDVEQAGGETDDKR---RA 239
Query: 245 TVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGF-- 302
L L V + L AG I + + ++++ A ++ + + +L F
Sbjct: 240 ITLWLLNGVIMFVL--AGFELGIVLQGQQHPTLSSREISLMFAECSLVMLIINAMLFFTG 297
Query: 303 LMKSLGAKHTIMVGLLFEMLQL-MWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNS 361
L++ + + GL + L M S TWM + AA + P IS +++ +
Sbjct: 298 LLERAAGRGVLAAGLALAIAGLAMLAQHRSDTWMYVGVSLTAAGTGLVLPTIS-FLAAGA 356
Query: 362 RADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
R G G + G +G A G +F F
Sbjct: 357 SRHRLGATMGGLASAAGFGQTIGSAAAGWLFGAF 390
>UniRef50_Q7XA81 Cluster: At2g16980; n=7; Arabidopsis thaliana|Rep:
At2g16980 - Arabidopsis thaliana (Mouse-ear cress)
Length = 461
Score = 50.4 bits (115), Expect = 1e-04
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 5/153 (3%)
Query: 246 VLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQ---VAIFIAIVGVLSIGVQVILGF 302
++ V F + E+G+ S + +YL F V Q +F+ + + SI IL
Sbjct: 259 LIQALVVTFFATFSESGRGSAL-MYLS-ESSFWVQQNDFAELFLLVTIIGSISQLFILPT 316
Query: 303 LMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISAYVSVNSR 362
L ++G + + GLL E W+ +A +L P++ S
Sbjct: 317 LSSTIGERKVLSTGLLMEFFNATCLSVAWSPWVPYAMTMLVPGAMFVMPSVCGIASRQVG 376
Query: 363 ADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
+ QG VQG ++GVR + P ++ + LF
Sbjct: 377 SSEQGKVQGCISGVRAFAQVVAPFVYSPLTALF 409
>UniRef50_Q0CD81 Cluster: Predicted protein; n=6;
Trichocomaceae|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 604
Score = 50.4 bits (115), Expect = 1e-04
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 12/149 (8%)
Query: 80 IKGILSFLSAPLIGALSDVWGRKFFLLVTVF---FTCAPIPL-------MTINTWWFFAM 129
+ GILS L +P +G +SD +GR + ++V F A + L M++N A+
Sbjct: 164 VAGILSALVSPRLGRISDRYGRTRIIALSVLGTLFAEANVLLVAANQEEMSVNMLLLSAI 223
Query: 130 IS-ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGES 188
I + G F ++ +Y +D T+ +RS A+G + + P L A+L+ G
Sbjct: 224 IDGLGGSFTTVLALTTSYASDCTSFKKRSVAFGYLHGCVFIGMAAGPLLVAFLIKSTGTI 283
Query: 189 LXXXXXXXXXXXXXFF-IMVAVPESLPEK 216
L F +++ +PESL ++
Sbjct: 284 LSVFYAAVALNAVFFLALLLVIPESLSKE 312
>UniRef50_Q8DGS3 Cluster: Tlr2241 protein; n=1; Synechococcus
elongatus|Rep: Tlr2241 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 408
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMT-----INTWWFFAM 129
GL + I SF+ L GA SD WGR F+ ++ + L+ ++ W +
Sbjct: 250 GLFYSVAAIASFIGRVLTGAASDRWGRGIFISASLAAYVVSMVLLAQAQTPLDVLWAAIL 309
Query: 130 ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
++G V +V A +AD +T ER R L F + ++ L L++ +G +
Sbjct: 310 EGLAG--GVLIPMVAALMADRSTPQERGRVLSLSLGGFDLGMALAGPLLGGLVEHWGYRV 367
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
F + A +SLP+ +R
Sbjct: 368 IFRMGAVFSLLGLAFFLTASSKSLPDSLR 396
Score = 43.6 bits (98), Expect = 0.012
Identities = 76/355 (21%), Positives = 133/355 (37%), Gaps = 23/355 (6%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHT-FLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
++F A L T+P+ + P F+M +G+ G S+L G L+D GR
Sbjct: 23 LLFWSSIAAMLPTLPLYIAQKGSTPHQVGFVMGAFAVGLLGSRSWL-----GPLADRRGR 77
Query: 102 KFFLLVTVFFTC-API-PLMTINTWWFFAMISISGVFAVTFSIVF-AYVADVTTEAERSR 158
K LL+ + AP+ +++ N A+ + GV F+ + A V D+ R
Sbjct: 78 KITLLIGLAVAAIAPLFYILSHNLPLLIAVRLLHGVSIAGFTTGYMALVTDIAPPQHRGE 137
Query: 159 AYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVR 218
G S + + P+LG++L YG M A + +
Sbjct: 138 IIGYTSLVHPIGVALGPSLGSWLQMHYGHDWVFIVASTLAALG---CMAAAGVRAVNRAQ 194
Query: 219 PTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFG 278
+G P A+ R + +ER L + V LS G + G
Sbjct: 195 ESGELP------AETTLFWRLLLSER--LRIPSLVMLSVGLTFGTIATFIPLFMAAEQLG 246
Query: 279 VVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTW-MMW 337
V +F ++ + S +V+ G G I L ++ ++ ++W
Sbjct: 247 -VSPGLFYSVAAIASFIGRVLTGAASDRWGRGIFISASLAAYVVSMVLLAQAQTPLDVLW 305
Query: 338 AAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGL-GPAMFGVI 391
AA + G + P ++A ++ S +G V + G L L GP + G++
Sbjct: 306 AAILEGLAGGVLIPMVAALMADRSTPQERGRVLSLSLGGFDLGMALAGPLLGGLV 360
>UniRef50_Q81S21 Cluster: Major facilitator family transporter;
n=12; Bacillus cereus group|Rep: Major facilitator
family transporter - Bacillus anthracis
Length = 404
Score = 50.0 bits (114), Expect = 1e-04
Identities = 74/363 (20%), Positives = 132/363 (36%), Gaps = 34/363 (9%)
Query: 40 ALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
+LV+ FL F+ I L T +GL G+ ++ + +P+ G L D+
Sbjct: 23 SLVIPFLSFY---------IEELGVTGTSSIAQWSGLAFGVTFLMGAIVSPIWGKLGDIH 73
Query: 100 GRKFFLLVTVFFTCAPIPLM--TINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERS 157
GRK L+ + LM + + A+ + G + S ++A T +
Sbjct: 74 GRKLMLIRASLGMAIIMTLMGFVTDVYQLVALRFLMGAVSGFLSTAMTFIAAETPKEHSG 133
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGES---LXXXXXXXXXXXXXFFIMVAVPESLP 214
A +S + ++ P LG YL +L G L FF + S
Sbjct: 134 WAISTISTGGVSGSLLGPLLGGYLSELIGMRHVFLVTGAFLFLSFLIVFFFLHEENHSAQ 193
Query: 215 EKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLV 274
K T W V A+ ++ L V F+ L + +Y+K +
Sbjct: 194 AKKVQT----KKVWTM---------VPAKHLIISLFVTTFIIQLANMSVQPIVTLYVKNL 240
Query: 275 MGFGVVQVAIFIAIVGVLSIGVQVI-----LGFLMKSLGAKHTIMVGLLFEMLQLMWYGF 329
+G + V + + G+ VI LG L +G + T++V L + + F
Sbjct: 241 VGPQTAHIETIAGAV-MSATGLAVILAAPRLGRLSDHIGPQKTLVVALFAAGIIFIPQAF 299
Query: 330 GSRTWMMWAAGVLAALGSI-TYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMF 388
+ W + L + P++ + ++ G + G + L N +GP +
Sbjct: 300 VTSAWQLLILRFLLGIAQAGLLPSVQTLLKQHTPTHVTGRIFGYNQSFQFLGNMIGPILG 359
Query: 389 GVI 391
G I
Sbjct: 360 GQI 362
>UniRef50_Q3A1Q0 Cluster: Putative transport protein; n=1;
Pelobacter carbinolicus DSM 2380|Rep: Putative transport
protein - Pelobacter carbinolicus (strain DSM 2380 / Gra
Bd 1)
Length = 390
Score = 50.0 bits (114), Expect = 1e-04
Identities = 68/326 (20%), Positives = 122/326 (37%), Gaps = 25/326 (7%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRK-FFLLVTVFFTCAPIPLMTIN--TWWFFAMIS 131
G+IMG+ G+ + L P + L D GR+ F + ++ P+ M ++ F+ +
Sbjct: 48 GIIMGVFGLAATLCRPWVSGLVDRIGRRRSFTVGSLMMVGLPVGYMLLSGPLAGFYPGLM 107
Query: 132 I----SGV-FAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
+ GV A+ F+ F +VAD+ + G+ + + + PAL + + YG
Sbjct: 108 LLRILHGVGMALCFTAAFTFVADIVPPERLNEGIGIFGISGLVGMAVGPALAEFALHRYG 167
Query: 187 ESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTV 246
V + LP PVI + D + V +
Sbjct: 168 -------FFAMFVVASLLAGVGLVAHLPLS------EPVIERQARDVDTSFLDVLKRPKI 214
Query: 247 LMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKS 306
+ + L L GQ S L VV V++F V + V++ G L
Sbjct: 215 TTVALLAILFGL---GQASTGNFVAPLAAARQVVHVSLFFVAYSVAAALVRIGGGRLADR 271
Query: 307 LGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALG-SITYPAISAYVSVNSRADR 365
+G I L+ L+ + W + AG + G + +P++++ +
Sbjct: 272 VGELRVIPYALVITGGGLLALSVAYQAWSLTLAGAVTGCGHGLLFPSLNSLAVRDEPGGI 331
Query: 366 QGVVQGMVTGVRGLCNGLGPAMFGVI 391
+G + G+ TG N G + G I
Sbjct: 332 RGKITGIYTGALDGGNFCGSILLGYI 357
>UniRef50_A0ILD1 Cluster: Drug resistance transporter, EmrB/QacA
subfamily precursor; n=2; Enterobacteriaceae|Rep: Drug
resistance transporter, EmrB/QacA subfamily precursor -
Serratia proteamaculans 568
Length = 495
Score = 50.0 bits (114), Expect = 1e-04
Identities = 27/115 (23%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 71 FLMNGLIMGIKGILSFLSAPLIGALSDVWGRK--FFLLVTVFFTCAPIPLMTINTWWFFA 128
F + G + + + ++ P+ G L+D+ GRK FF ++F + + + N +W
Sbjct: 48 FSLLGWVFAVYLLAQAITIPIYGRLADLLGRKRVFFFGASLFLLGSVLCGFSPNMYWLIG 107
Query: 129 MISISGVFA-VTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLM 182
+ G+ A + D+ + ER + G +S+ + S +I P LGA+++
Sbjct: 108 FRLLQGLGAGAIMPTATTIIGDIYSPTERPKVMGYISSVWGVSAIIGPLLGAFIV 162
>UniRef50_Q16VM5 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 451
Score = 50.0 bits (114), Expect = 1e-04
Identities = 62/337 (18%), Positives = 135/337 (40%), Gaps = 26/337 (7%)
Query: 80 IKGILSFLSAPLIGALSDVWGRKFFLLVT----------VFFTCAPIPLMTINTWWFFAM 129
+ ++ + A +G SD +GRK + + V + C ++ WW+
Sbjct: 76 LTSVVPAMVALFLGPWSDKFGRKPVIAIASTGYMLTEMLVAWVCYMSNYYALSPWWYVVA 135
Query: 130 ---ISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
+SISG ++V + +F+Y++DVT E R+ G++ ++I +Y++D
Sbjct: 136 NIPVSISGGYSVFNAGLFSYMSDVTNERNRTLRMGVLQGCTMLGVLIGLLASSYMIDSVS 195
Query: 187 ESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPV-------ISWEQADPFAALRK 239
++ ++ + E++ + +G + + E F R
Sbjct: 196 ATVMFLISTAGMFLGIVYLALVTKETIINENIRSGVDKIKAIFNISLLLEMVHTFTKPR- 254
Query: 240 VGAERTVLMLCVAVF-LSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFI-AIVGVLSIGVQ 297
ER + L ++V L AG+ F+Y + G+ V ++ A +G++ +G
Sbjct: 255 WNYERAITWLLISVSGLVEFAIAGR-QLFFLYTRRQFGWDAVTYGFWLSAELGLIMMGNL 313
Query: 298 VILGFLMK--SLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISA 355
+G L K ++ + + + ++ + GF W ++ ++ L + AI +
Sbjct: 314 FGIGLLKKLFNISDLSLLAISTMNQLGDYLIKGFAQEGWQLYLTTLMTPLKGVDGAAIRS 373
Query: 356 YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF 392
+S D G M V+ + + +F I+
Sbjct: 374 MLSSILPKDDIGKSYSMDLSVKAITPLISVFLFTSIY 410
>UniRef50_Q0E8E1 Cluster: CG32158-PC, isoform C; n=5;
Endopterygota|Rep: CG32158-PC, isoform C - Drosophila
melanogaster (Fruit fly)
Length = 533
Score = 50.0 bits (114), Expect = 1e-04
Identities = 71/349 (20%), Positives = 148/349 (42%), Gaps = 32/349 (9%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTV---FFTCAPIPLMTINTWW------FFAMI--S 131
+ + A +G+ SD GRK LL+ + FF I + T W + A + +
Sbjct: 129 VFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIYSATLPSA 188
Query: 132 ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLM-DLYGESLX 190
++G F+ FAY++D+++ +R+ ++ + +++ + ALG++L +++ +S
Sbjct: 189 LTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFNQSYA 248
Query: 191 --XXXXXXXXXXXXFFIMVAVP-ESLPEK--VRPTG----WGPVISWEQA-DPFAALRK- 239
+ + A+ ++ P + +R G WG + D A L K
Sbjct: 249 DMFTVNASLLALAIIYTLCALKWQTTPRQRSLRELGCCGFWGDFFDKQHVKDSLAVLVKP 308
Query: 240 -VGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAI-VGVLSIGVQ 297
G R+ L++ + Y + + +++Y + V + F I +
Sbjct: 309 RKGHRRSFLIILLVSMALYTFQRDEGQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAML 368
Query: 298 VILGFLMKSLGAKHT--IMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISA 355
+ + + K LG + T I +G + +++ F + T +++A V+ +LG I P I A
Sbjct: 369 LAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRA 428
Query: 356 YVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIF-YLFHVDLNEGH 403
S +G V +++ +C+ P + GV + L+ N H
Sbjct: 429 MTSKIVPTSERGKVFALLS----VCDNAVPFISGVCYSQLYRRTQNTNH 473
>UniRef50_Q97WR9 Cluster: Multidrug resistance protein; n=6;
Sulfolobaceae|Rep: Multidrug resistance protein -
Sulfolobus solfataricus
Length = 472
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTF 140
I+ +++PL G L D +G+K L+++ F + L +T +F + + I G+ TF
Sbjct: 54 IVGAIASPLFGKLGDRYGKKKVYLLSIGFYSLAVLLAGFSTNIYFLIFARAIQGLGYATF 113
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
+ A + D+ + + A G++SAT AA + +G+Y++ G
Sbjct: 114 PLAIAIITDLFPKERVAWAQGILSATLAAGPALGLLVGSYIVQDLG 159
>UniRef50_O28265 Cluster: Sugar transporter, putative; n=1;
Archaeoglobus fulgidus|Rep: Sugar transporter, putative
- Archaeoglobus fulgidus
Length = 401
Score = 50.0 bits (114), Expect = 1e-04
Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 8/162 (4%)
Query: 32 IGEPSVFHALVVIFLEFFAW-----GLLTMPIISV-LNATFPDHTFLMNGLIMGIKGILS 85
+GE S F L+V+ W GL + ++ + F T L G I + I
Sbjct: 1 MGEFSKFEKLIVLLAAAIGWSHDAVGLTLLNFLAEPIMREFNVGT-LEIGFIFSAQYIFC 59
Query: 86 FLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTIN-TWWFFAMISISGVFAVTFSIVF 144
A L G + D +GRK L++++ + L +W A++ + VT+ + F
Sbjct: 60 IFGAMLFGEMGDRFGRKNALILSILWVAVFSVLSAFAPNFWTLAILRLISGMGVTWGLAF 119
Query: 145 AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
Y+++ + R GL+ ATF ++S + + +YG
Sbjct: 120 TYMSEFYSPKRRGLFGGLIHATFVFGFILSALSVSLIYPIYG 161
>UniRef50_A4G090 Cluster: Major facilitator superfamily MFS_1; n=4;
Methanococcus|Rep: Major facilitator superfamily MFS_1 -
Methanococcus maripaludis
Length = 383
Score = 50.0 bits (114), Expect = 1e-04
Identities = 68/355 (19%), Positives = 143/355 (40%), Gaps = 19/355 (5%)
Query: 42 VVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGR 101
+ IF+ GL++ P++++ ++ F + GLI G + + G LSD +G+
Sbjct: 13 ITIFVTMLGIGLIS-PLLAIFAKSYGLSNFQI-GLIFGSFALARTIFQLPAGTLSDNYGK 70
Query: 102 KFFLLVTVFFTCAPIPLMTINTWWFFAMI--SISGVFAVTFS-IVFAYVADVTTEAERSR 158
K FL+ F + + + ++ + +GVF+ + I +Y+A ++ +++
Sbjct: 71 KVFLVGGTFLYGVTTLFYGLVSGFASILLVRTFTGVFSAFVNPIAGSYIAQISPKSKLGE 130
Query: 159 AYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES-LPEKV 217
G+ ++ A + P LG L D+YG + + E P +
Sbjct: 131 YMGVFNSAIALGFGVGPLLGGLLADMYGFLVPFYVGGFLGIIASIIAYFKLDEGPKPLEK 190
Query: 218 RPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGF 277
+ W + S E F +R A ++ +A+ +S Y I+ Y G
Sbjct: 191 QKLAWKNLFSLE----FLKMRNFSA---AFIINIALTIS-RGAILAYLAIYAY---DYGI 239
Query: 278 GVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMW 337
++ +A + + Q G + G I+ G+ L + + M+
Sbjct: 240 SAFKIGAMLAAMNFVLAVTQKKFGKIFDEKG-NSIILHGIFIGNLGMFVLAMSTSFTAMF 298
Query: 338 AAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
+ ++A++G S++ P I++ + +R+G G+ T + G + G I
Sbjct: 299 ISLIIASIGASMSTPGINSIAIRDIPHERKGEAMGLYTASINVGIFSGAVLLGYI 353
>UniRef50_Q9ZBJ1 Cluster: Putative efflux protein; n=3;
Streptomyces|Rep: Putative efflux protein - Streptomyces
coelicolor
Length = 815
Score = 49.6 bits (113), Expect = 2e-04
Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRK--FFLLVTVFFTCAPIPLMTINTWWFFAMISISGVFAVTF 140
+ S + P+ G L D++GRK F + VF + + A ++ GV A
Sbjct: 94 LTSTVGLPIYGKLGDLFGRKGVFQFAILVFVVGSALAGRAQTMDQLIAFRAVQGVGAGGL 153
Query: 141 SI-VFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
I V A +AD+ ER+R GL+ A+F + V P LG Y D
Sbjct: 154 MIGVQAIIADIVPPRERARYMGLIGASFGLASVAGPLLGGYFTD 197
>UniRef50_Q8NTC7 Cluster: Permeases of the major facilitator
superfamily; n=9; cellular organisms|Rep: Permeases of
the major facilitator superfamily - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 549
Score = 49.6 bits (113), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Query: 87 LSAPLIGALSDVWGRKFFLL--VTVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVF 144
+S P+ G L D +GRK+ + + +F + I + N ++ G+ I+
Sbjct: 98 ISLPIFGKLGDQFGRKYLFMFAIALFVVGSIIGALAQNMTTLIVARALQGIAGGGLMILS 157
Query: 145 -AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
A ADVTT ER++ G++ + F S ++ P LG + D
Sbjct: 158 QAITADVTTARERAKYMGIMGSVFGLSSILGPLLGGWFTD 197
>UniRef50_Q81KN5 Cluster: Drug resistance transporter, EmrB/QacA
family; n=11; Bacillus cereus group|Rep: Drug resistance
transporter, EmrB/QacA family - Bacillus anthracis
Length = 478
Score = 49.6 bits (113), Expect = 2e-04
Identities = 34/112 (30%), Positives = 61/112 (54%), Gaps = 6/112 (5%)
Query: 77 IMGIKGILSFLSAPLIGALSDVWGRKFFLLV--TVFFTCAPI--PLMTINTWWFFAMISI 132
+ I + + +S P+ G L+D++GRK LL+ T+F + + + ++ FF +
Sbjct: 43 VYAIYMLATAVSTPIYGKLADLFGRKKVLLIGATIFLVGSALCGVVTSMEQLIFFRALQG 102
Query: 133 SGVFAVTFSIVFAYVADVTTEA-ERSRAYGLVSATFAASLVISPALGAYLMD 183
G AV I + D+ +EA +R++A G +SA + S VI P +G +L+D
Sbjct: 103 IGAGAV-MPITMTIIGDLYSEAKDRAKAQGWMSAVWGVSGVIGPLVGGFLVD 153
>UniRef50_Q9ZF64 Cluster: Multidrug-efflux transporter; n=17;
Campylobacter|Rep: Multidrug-efflux transporter -
Campylobacter jejuni
Length = 431
Score = 49.6 bits (113), Expect = 2e-04
Identities = 70/365 (19%), Positives = 147/365 (40%), Gaps = 27/365 (7%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK 102
++ FF + +P++S+ + GL++G+ + + G LSD GRK
Sbjct: 11 IVGTRFFGL-FIVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFGILSDKIGRK 69
Query: 103 FFLLV--TVFFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAY 160
+L+ +F + I N + + G A+ ++ A ++D TE R +A
Sbjct: 70 KTMLIGLIIFIIGSLICSFAENIYTMLLGRMLQGAGAIG-AVATAMISDFITEENRGKAM 128
Query: 161 GL----VSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEK 216
+ + +FAAS+VISP + A +G S + VP+
Sbjct: 129 AVMGSFIGLSFAASMVISPLMSA----KWGLSSLFDLSAALSLLCIILLYTVVPKE---- 180
Query: 217 VRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMG 276
+ + PF L K ++ + ++ + F+ + + + I + L +G
Sbjct: 181 ------NKITHENEKTPFFHLIK---QKNLALMNLTNFMQKMLMSIAFLSIPIILVKHLG 231
Query: 277 FGVVQVAIFIAIVGVLSIGVQVILGFLMKSLG-AKHTIMVGLLFEMLQLMWYGFGSRTWM 335
F ++ I + V G L + G AK +++G++F +L +++ F +
Sbjct: 232 FASDKLWIVYSASMVAGFIAMGFAGSLGEKRGLAKQILLLGIVFFILSYLFFAFSNSIDF 291
Query: 336 MWAAGVLAALG-SITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
A V+ +G ++ P + + S + +G G+ + +G + G+ +L
Sbjct: 292 FIIAVVIFFIGFNLHEPIMQSCASKFCKVHEKGAALGLFNAFGYGGSFIGGIIGGIFLHL 351
Query: 395 FHVDL 399
++L
Sbjct: 352 DTLNL 356
>UniRef50_Q1AS00 Cluster: Major facilitator superfamily MFS_1; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Major facilitator
superfamily MFS_1 - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 411
Score = 49.6 bits (113), Expect = 2e-04
Identities = 81/358 (22%), Positives = 134/358 (37%), Gaps = 13/358 (3%)
Query: 41 LVVIFLEF-FAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
LV L F F GL P ++ F + G +G+ S LS G L+D +
Sbjct: 25 LVGAMLVFRFGQGLF-YPFSTIYFHNFVGIPLSLIGAGLGLLAAASVLSGLASGPLADRY 83
Query: 100 GRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVF--AYVADVTTEAE 155
GRK +L + + A L + A ++G+ + A VADVT
Sbjct: 84 GRKPVMLAALSGSAASFALFAAAGGLPGYLAACLVAGLAGSSMFDASRNAMVADVTPAGL 143
Query: 156 RSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE 215
R+RAYGLV + PA + G S ++ L
Sbjct: 144 RARAYGLVRVGGNVGWALGPAAAGLVAASAGSSAGTYRLMFAGTAALTLLVALSLALLVA 203
Query: 216 KVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVM 275
+ RP + + P ALR+ ++ L A FL Y A + + VY + +
Sbjct: 204 ESRPA----LAAGGSPSP-GALREALSDGRFAALLGAAFLLYYVFAQDWQALPVYARNFL 258
Query: 276 GFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMV-GLLFEMLQLMWYGFGSRTW 334
G ++ +F+A G++ I +Q+ + L+ + ++V LLF S
Sbjct: 259 GMEEGRIGLFLAGNGLVVILLQMPVARLLDARSKMGALLVCSLLFAASAATLLITESFLG 318
Query: 335 MMWA-AGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVI 391
++ A AG I A +A + + R+G + G G+ P + G +
Sbjct: 319 ILVAFAGFFTLAEMILEVAGAALAAGMAPPGRRGTYLALFGVCFGAAQGISPVVAGAL 376
>UniRef50_Q04DH7 Cluster: Permease of the major facilitator
superfamily; n=1; Oenococcus oeni PSU-1|Rep: Permease of
the major facilitator superfamily - Oenococcus oeni
(strain BAA-331 / PSU-1)
Length = 409
Score = 49.6 bits (113), Expect = 2e-04
Identities = 70/347 (20%), Positives = 129/347 (37%), Gaps = 11/347 (3%)
Query: 56 MPIISVLNATFPDHTFLMNGLIMGIKGILSFLS----APLIGALSDVWGRKFFLLVTVFF 111
+P +S+ T + T L GI +FL +P+ G L+D GRK L+
Sbjct: 33 LPFLSLFTETLGNFTKAEVNLYSGIAFSSTFLMTAIVSPIWGKLADRVGRKPMLIRAALG 92
Query: 112 TCAPIPLMTINT--WWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAA 169
L +T W + + G F S A VA T + A G+V + +
Sbjct: 93 MAVVYTLTGFSTSVWVLIGLRFLMGFFNGYVSNANALVAKDTPKIYSGHALGIVVTGYTS 152
Query: 170 SLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWE 229
+I P LG +L +++G + F ++ V E V G S
Sbjct: 153 GALIGPLLGGFLANIFGYRMPFFITGSILFLLTFLTLIGVHEDKSTLVTKKTTGKQPSAL 212
Query: 230 QADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIV 289
++ + + V M+ V S P QY + L+ + + A
Sbjct: 213 KSAKYPMM--VFGLFITSMIVNLVTNSINPILSQY--VRQLLEPNESHLSMIAGLIAAAP 268
Query: 290 GVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSIT 349
G+ +I G L +G++ ++ G L ++ ++ F S W+++ + L +
Sbjct: 269 GMTAIIFAPRFGRLGDRIGSEKLVIGGFLIGIVSMIPMAFVSNVWVLFVLRLFIGLTTAA 328
Query: 350 Y-PAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYLF 395
PAI A ++ + + + + N GP + ++ +F
Sbjct: 329 MNPAIQAILAHETPQEFTSRIFSYNQSFLAMGNVFGPLLGSLVANIF 375
>UniRef50_A0W4A2 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Geobacter lovleyi SZ|Rep: Major
facilitator superfamily MFS_1 precursor - Geobacter
lovleyi SZ
Length = 395
Score = 49.6 bits (113), Expect = 2e-04
Identities = 84/373 (22%), Positives = 136/373 (36%), Gaps = 23/373 (6%)
Query: 27 MTMSGIGEPSVFHALVVIFLEFFAWGLLTMPIISVLNATF---PDHTFLMNGLIMGIKGI 83
MT + G S F L +I F L +P++ + AT P L+NG M GI
Sbjct: 1 MTHTKHGRAS-FVLLCLIGSATFFSSYLRIPVLPLFAATLGAGPAQVGLINGAFMVTAGI 59
Query: 84 LSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMT--INTWWFFAMISISGVFAVTFS 141
LS + G L D GR ++ + T A L+T + A+ + G F+
Sbjct: 60 LSIPA----GLLVDRLGRTKPVIGGIVATAASSLLVTQCSSPLQLVAVYLLFGAGLAAFA 115
Query: 142 -IVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
+ + VAD+ RAYG + ++ I PA G YL G
Sbjct: 116 PAMLSLVADIVPSERLGRAYGWYTTAIYVAMTIGPATGGYLAKTVGLRNVFLVSGTMLAT 175
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
++ +P + S LR T + +FL++LP
Sbjct: 176 MALLALLVLPRTAARHKTELHAALAASLTLLHN-RPLRACLLATTGSCIGFGLFLTFLP- 233
Query: 261 AGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFE 320
+F G QV + A + ++ +V +G + L + + GL
Sbjct: 234 ------LFA---ASHGLDPGQVGLVFAAQAITNVVGRVPIGMIADRLERRLLVSAGLFCL 284
Query: 321 MLQLMWYGFGSR-TWMMWAAGVLAALGSITYPAISAYVSVNSRADRQGVVQGMVTGVRGL 379
L L G ++ +WM+ A + + T+ AISA + ++G+ GM L
Sbjct: 285 ALALPALGQTTQLSWMVLCAVGMGIGMAFTFTAISALIVEQVPTVQRGLAMGMYNSCIYL 344
Query: 380 CNGLGPAMFGVIF 392
G G+ F
Sbjct: 345 GMMTGSTAMGIAF 357
>UniRef50_Q5WG02 Cluster: Multidrug-efflux transporter; n=1;
Bacillus clausii KSM-K16|Rep: Multidrug-efflux
transporter - Bacillus clausii (strain KSM-K16)
Length = 407
Score = 49.2 bits (112), Expect = 2e-04
Identities = 76/379 (20%), Positives = 142/379 (37%), Gaps = 28/379 (7%)
Query: 29 MSGIGEPSVFHALVVIFLEFFAWGLLTM--PIISVLNATFP----DHTFLMNGLIMGIKG 82
M GI +P + L++ F FF +TM P +S+ +F D G + +
Sbjct: 1 MIGI-QPEKRNLLIMWFANFFVSASMTMVIPFLSLYIESFGHYNVDEVQRWAGYVFAVSF 59
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLM--TINTWWFFAMISISGVFAVTF 140
++FL APL G + D +GRK LL T + M + F + + G+
Sbjct: 60 FVAFLVAPLWGKIGDRFGRKKVLLGTGLGIALSVFFMGYVHSAEQLFVLRAFMGLATGFI 119
Query: 141 SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXX 200
A +A +++ G + + ++ P G + D G L
Sbjct: 120 PASMALIAAQSSKKTAGEMLGTLQTGTVSGGLLGPLFGGLIADTVGMELTFLLTSSILLI 179
Query: 201 XXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPE 260
+++ V E + E+ E+ + + +G +L + +F++ + +
Sbjct: 180 ATVLVLIGVKEVVYEE----------KGERKRKYRSKEVLGRIVKSPLLLMVMFVALIVQ 229
Query: 261 AGQYS---CIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVIL---GFLMKSLGAKHTIM 314
+S + +Y+ + + A V +G ++ G +G + +M
Sbjct: 230 MALFSVQPLLALYVNQITHNTENMAFLAGAAFSVTGLGNLILTRTWGQFGDRIGHEKVMM 289
Query: 315 VGLLFEMLQLMWYGFGSRTWMMWAAGVL--AALGSITYPAISAYVSVNSRADRQGVVQGM 372
+ LL L + F W + L A+G + P +A++ QG V G
Sbjct: 290 ILLLLSGLLFIPQAFVGSLWQLIVLRFLFGMAVGGL-LPCTTAFIRQACPVAMQGEVLGY 348
Query: 373 VTGVRGLCNGLGPAMFGVI 391
R L N LGP + G+I
Sbjct: 349 NQSFRFLGNVLGPVLGGMI 367
>UniRef50_A0H326 Cluster: Major facilitator superfamily MFS_1; n=2;
Chloroflexus|Rep: Major facilitator superfamily MFS_1 -
Chloroflexus aggregans DSM 9485
Length = 468
Score = 49.2 bits (112), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 10/172 (5%)
Query: 19 KTVMKDGIMTMSGIGEPSVFHALV-VIFLEFFAWGL---LTMPIISVLNATFP-DHTFLM 73
++ + G+M + E A++ V+F+ F L + PI+ L A F D+T ++
Sbjct: 11 RSTNEGGLMASVAVPETDTRRAIMTVLFVGVFMSALDSAIIGPIVPALRAAFAIDNTQVV 70
Query: 74 NGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMI--S 131
L+ I + S S L+ +LSD +GR+ L+ VF ++ ++ +I +
Sbjct: 71 --LVSIIFTLCSLSSTTLMASLSDRYGRRHVYLLNVFGFAIGSLVIALSHDLMTVLIGRA 128
Query: 132 ISGVFAVTFS-IVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLM 182
+ G+ A + A + DV ER++A GL+ AT + +I P L + ++
Sbjct: 129 LQGICAGGITPTASAVIGDVLPPVERAKALGLIGATSGMAFLIGPVLASLIL 180
>UniRef50_Q19296 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 445
Score = 49.2 bits (112), Expect = 2e-04
Identities = 25/108 (23%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFT-CAPIPLMTINTWWFFAMISI- 132
G + + L F+S+P +G+LSD++GR+ + + T + + + + + +F + I
Sbjct: 80 GFLGSLFSALQFISSPTLGSLSDIYGRRAVISLCCIMTFISYVNWLKADIFAYFVLSRIL 139
Query: 133 SGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAY 180
G+ ++ A V+DV + + + L+ +++ +I P +GAY
Sbjct: 140 GGLSKGNINVATAIVSDVYSPEDHPKGMALIGISYSLGFLIGPMIGAY 187
>UniRef50_Q9UYY0 Cluster: Multidrug resistance protein; n=4;
Thermococcaceae|Rep: Multidrug resistance protein -
Pyrococcus abyssi
Length = 410
Score = 49.2 bits (112), Expect = 2e-04
Identities = 37/115 (32%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRK-FFLLVTVFFTCAPIPLMTINTWWFFAMISI- 132
G + GI + + LSA +IG L D +G K FF L V + + N+ A+ISI
Sbjct: 274 GYLFGIDSLSAALSALIIGRLIDKYGEKLFFRLSLVGYIITFMGYALANSVIIMALISIL 333
Query: 133 SGV-FAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
SG+ + + + YVA +ER + GL++ VI P +G L D +G
Sbjct: 334 SGLKWTMLTNSSSTYVARRVPTSERGQGMGLLNTMMTLGWVIGPLIGGILADNFG 388
>UniRef50_Q4J724 Cluster: Drug transporter; n=1; Sulfolobus
acidocaldarius|Rep: Drug transporter - Sulfolobus
acidocaldarius
Length = 396
Score = 49.2 bits (112), Expect = 2e-04
Identities = 59/319 (18%), Positives = 132/319 (41%), Gaps = 26/319 (8%)
Query: 33 GEPSVFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLI 92
G+ ++ + FL+ +G++ +PI+ + T + L+ I + +P I
Sbjct: 11 GKITLITLALTAFLDSVGFGII-IPILPYYSLQL-GATPIEYSLLTVTYSIAQLVFSPYI 68
Query: 93 GALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADV 150
LSD+ GRK L + + ++ ++ +++ +++ I+G ++ +Y ++
Sbjct: 69 SRLSDIRGRKNILTLGIGSEVVGYLIIGLSPYFYLLLLARFITGALTSNLPVILSYATEL 128
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYLMDL-YGESLXXXXXXXXXXXXXFFIMVAV 209
+ SR G++S TF V P +G L L Y + +++V+
Sbjct: 129 GKD--NSRNIGIISGTFGVGFVAGPVIGGVLSPLGYRNTFLIVAGLAFLNLILVYLLVSN 186
Query: 210 PESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFV 269
I+ QA + ++ + L L +A+ + L Q + F
Sbjct: 187 DNK------------KIAMRQAS-LKEIFRMSSSFFTLTLIIALSFAVL----QGTLAF- 228
Query: 270 YLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGF-LMKSLGAKHTIMVGLLFEMLQLMWYG 328
Y + +G Q+ + + +VG++ Q +L + ++ G + +GL + +
Sbjct: 229 YGRYFYNWGPSQIGLVLGLVGIVQAVAQFLLVYRIIGKAGERIATTIGLSITFIAYILLS 288
Query: 329 FGSRTWMMWAAGVLAALGS 347
F S + + + VL A+G+
Sbjct: 289 FPSNQILAYVSLVLLAMGN 307
>UniRef50_Q3SA88 Cluster: Permease of the major facilitator
superfamily; n=2; Euryarchaeota|Rep: Permease of the
major facilitator superfamily - uncultured euryarchaeote
Alv-FOS4
Length = 484
Score = 49.2 bits (112), Expect = 2e-04
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Query: 77 IMGIKGILSFLSAPLIGALSDVWG-RKFFLLVTVFFTCAPIPLMTINTW-WFFAMISISG 134
I+ + ++ +S ++G L D++G R+ FL+ F+T T+ W + G
Sbjct: 53 ILSMYLLVGTVSVAVMGKLGDMFGKRRMFLIALTFYTAGVTMNGFAPTYQWLLFSRGLQG 112
Query: 135 VFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
V F + F+ V + GL+SA FA +VI+ LGAY+ YG
Sbjct: 113 VGMSIFPLGFSLVREEFPPEMVPEVQGLISAMFAVGMVIALPLGAYISQNYG 164
>UniRef50_A1RZ13 Cluster: Major facilitator superfamily MFS_1; n=1;
Thermofilum pendens Hrk 5|Rep: Major facilitator
superfamily MFS_1 - Thermofilum pendens (strain Hrk 5)
Length = 440
Score = 49.2 bits (112), Expect = 2e-04
Identities = 61/254 (24%), Positives = 104/254 (40%), Gaps = 8/254 (3%)
Query: 76 LIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT-WWFFAMISISG 134
L+ + + LS + G LSD +GRK L V F LM++ T W +A+ S+
Sbjct: 78 LVQSATQVANALSRIVGGFLSDRYGRKRVLWVGTFLVALAYLLMSVATDWRSYAIASVLN 137
Query: 135 VFAVTFSIVFAYV-ADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXX 193
FA+ + + AD R R L+ + +SP GA L++ YG
Sbjct: 138 GFALFYQPALEGIQADSVPLHLRGRMNALLHLVPGLASSLSPLGGAALVNAYGLVGGVRV 197
Query: 194 XXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAV 253
I VA + E + P G G + D ALR V R V L
Sbjct: 198 IFFLSFVTGVAIAVARLLWIEETLEPRGSGVNMLESYVD---ALRHV--SRDVYTLITLD 252
Query: 254 FLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTI 313
L L A + + Y+ +G ++A+ ++ ++++G+ + G + + G +I
Sbjct: 253 TLFNLVGAMSFLSNY-YMYYYLGVDKSELAMLASLGSLVNLGLLIPAGRAVDTRGRNFSI 311
Query: 314 MVGLLFEMLQLMWY 327
+G L L +++
Sbjct: 312 TLGFLMGTLSQLFF 325
>UniRef50_O25793 Cluster: Multidrug-efflux transporter; n=4;
Helicobacter|Rep: Multidrug-efflux transporter -
Helicobacter pylori (Campylobacter pylori)
Length = 443
Score = 48.8 bits (111), Expect = 3e-04
Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+F +V L F + +P+IS+ +F + L+ GL +G + + +G LS
Sbjct: 5 IFPLALVSSLRFLGL-FIVLPVISLYADSFHSSSPLLVGLAVGGAYLTQIVFQTPMGILS 63
Query: 97 DVWGRKFFLLVTV--FFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEA 154
D GRK ++V + F + + + + W I G+ A+ ++ A VAD E
Sbjct: 64 DKIGRKVVVMVCLLLFLAGSLVCFIANDIVWLVIGRFIQGMGALG-GVISAMVADEVKEE 122
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
ER++A ++ A S IS A+G ++ G
Sbjct: 123 ERTKAMAIMGAFIFISFTISMAIGPGVVAFLG 154
>UniRef50_Q2BLG1 Cluster: Major facilitator family transporter; n=1;
Neptuniibacter caesariensis|Rep: Major facilitator
family transporter - Neptuniibacter caesariensis
Length = 407
Score = 48.8 bits (111), Expect = 3e-04
Identities = 43/155 (27%), Positives = 76/155 (49%), Gaps = 8/155 (5%)
Query: 37 VFHALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALS 96
+ H + F+ F + + T I++ L + T G + + GI+S S L G +S
Sbjct: 227 ISHVGAIYFMFGFTYVIYTTFIVTSLVEEY-HFTEAKAGNLWMLIGIISVFSGALFGWVS 285
Query: 97 DVWGRKFFLL-VTVFFTCAPIPLMTINTWWFFAMISISGVFAVT-FS---IVFAYVADVT 151
D +GRK L+ V + TC+ + L NT +S+ +FA+T FS I+ A V+D+
Sbjct: 286 DKFGRKNGLISVYLMQTCSYL-LAASNTGEISLYLSML-LFALTAFSIPAIIAATVSDML 343
Query: 152 TEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
AE + +G V+ F + P + ++ ++ G
Sbjct: 344 PPAEAGKVFGYVTIFFGIGQIFGPTIAGFIAEVTG 378
>UniRef50_A6CVR9 Cluster: Putative nucleoside transporter YegT; n=1;
Vibrio shilonii AK1|Rep: Putative nucleoside transporter
YegT - Vibrio shilonii AK1
Length = 428
Score = 48.8 bits (111), Expect = 3e-04
Identities = 82/366 (22%), Positives = 155/366 (42%), Gaps = 32/366 (8%)
Query: 43 VIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSD-VWGR 101
++F+E+F WG +P+ +L+ T + I + LS L+G+++D +
Sbjct: 11 MMFIEWFIWGAWFVPLWQILSTNGFTPTEI--AWSYACTAIAAILSPILVGSITDRFFPA 68
Query: 102 KFFLLVTVFFTCAPIPLMTINTWW--FFAMI-----SISGVFAVTFSIVFAYVADVTTEA 154
+ L V + + L T + FF ++ + A+T SI F+ V DV +
Sbjct: 69 QKVLSVMLLAGAVLMYLAAQQTEFATFFPLLLGYSLTYMPTIALTNSIAFSNVEDVERDF 128
Query: 155 ERSRAYGLVSATFAASLVISPALGAYLM--DLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
R R G + + AS V L ++L D+ ++ F + +P +
Sbjct: 129 PRIRVMGTIG--WIASGVAIGFLPSWLGYGDISSSNIPLIITAASSALLGIFALT-LPNT 185
Query: 213 LPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIFVYLK 272
P+ TG + D L+ +R L V F+ +P A Y +L
Sbjct: 186 PPKS---TGKLDLKVMLGLDAMVLLK----DRNFLAFFVCSFMFSMPLAFYYIFANGFLT 238
Query: 273 LVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSR 332
V G+ ++ + I + L F K G K +++GL ++ ++ +GS
Sbjct: 239 EV---GMSNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLLLGLATAAIRYGFFVYGSA 295
Query: 333 -TWMMWA---AGVLAALGSITYPAISAYVSVNSR--ADRQGVVQGMVT-GVRGLCNGLGP 385
TW +++ G+L S + ++AY+ V+ + A + QG++T G +G+ + LG
Sbjct: 296 DTWYLYSLLFLGILLHGVSYDFYFVTAYIYVDKKAPAHMRTAAQGLITLGCQGIGSLLGY 355
Query: 386 AMFGVI 391
+ GV+
Sbjct: 356 RLGGVL 361
>UniRef50_A5WGZ2 Cluster: Major facilitator superfamily MFS_1; n=5;
Moraxellaceae|Rep: Major facilitator superfamily MFS_1 -
Psychrobacter sp. PRwf-1
Length = 454
Score = 48.8 bits (111), Expect = 3e-04
Identities = 37/137 (27%), Positives = 69/137 (50%), Gaps = 3/137 (2%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK--FFLLVTVFF 111
+ +P+ SV + T L+ GL +GI G+ L + +D + RK FL + +F
Sbjct: 25 MIVPVFSVYGNNYAHATPLLIGLAVGIYGLGQALFQIPMSMAADKFPRKPMIFLGLLLFA 84
Query: 112 TCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASL 171
+ + + +++G AV+ +I+ A +ADVT E +R++A + T A S+
Sbjct: 85 IGGVVAATATDIYQVIIGRALAGSGAVS-AILMALLADVTREQQRTKAMATMGLTIATSI 143
Query: 172 VISPALGAYLMDLYGES 188
++S A+G ++ G S
Sbjct: 144 MLSFAIGPMMVASLGIS 160
>UniRef50_A0YM33 Cluster: General substrate transporter; n=4;
Cyanobacteria|Rep: General substrate transporter -
Lyngbya sp. PCC 8106
Length = 421
Score = 48.8 bits (111), Expect = 3e-04
Identities = 70/323 (21%), Positives = 121/323 (37%), Gaps = 13/323 (4%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFTCAPIPLMTINTWWFFAMI-SI 132
GL+MG I S +G L+D GRK LL+ T T AP+ + + + A+I +
Sbjct: 51 GLVMGAFAIGLLPSRFGLGPLADSKGRKLVLLIGTTVVTLAPLGYLWVTSIPSMAVIRAF 110
Query: 133 SGVFAVTFSIVF-AYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXX 191
GV F+I + A VAD+ R G +S + I PA G ++ G +
Sbjct: 111 HGVSLAAFTIGYSALVADIAPIDRRGEVIGYMSLVTPIGMAIGPAFGGFVQAGLGYNFLF 170
Query: 192 XXXXXXXXXXXFFIMVAVPESLP----EKVRPTGWGPVISWEQADPFAALRKVGAERTVL 247
I + P + + P I ++ + L A RT
Sbjct: 171 LSSATFGLLAGLGISQVWEPTRPKPTLDNIDLISVTPKIRLQKLFRYFKLIGSPALRTPA 230
Query: 248 MLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSL 307
+ V L + G F+ L L + +F + + S ++ +G
Sbjct: 231 FVMAIVGLIF----GSL-VTFLPLYLAESNLELNAGLFYSTAAIASFSSRLFVGRASDRY 285
Query: 308 GAKHTIMVGLLFEMLQLMWYGFGS-RTWMMWAAGVLAALGSITYPAISAYVSVNSRADRQ 366
G I + L+ ++ ++ G + + ++ AA + A I P + V+ AD +
Sbjct: 286 GRGMFITIALILYLISMLLLGTANHHSEILLAAALEGAGAGILIPTVITLVTDRCSADER 345
Query: 367 GVVQGMVTGVRGLCNGLGPAMFG 389
G + G + L +FG
Sbjct: 346 GQFFSLCIGGFDIGIALAGPVFG 368
>UniRef50_A0JU53 Cluster: Drug resistance transporter, EmrB/QacA
subfamily; n=5; Actinomycetales|Rep: Drug resistance
transporter, EmrB/QacA subfamily - Arthrobacter sp.
(strain FB24)
Length = 538
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 90 PLIGALSDVWGRK-FFLLVTVFFTCAPIPLMTINTWWFFAMI-SISGVFAVTFSIVF-AY 146
P+ G DV GR+ FL+ FT A + +W F + +I G+ I+ A
Sbjct: 75 PIYGKFGDVLGRRNLFLVAIALFTLASVGCAFATDFWGFVVFRAIQGLGGGGLMILSQAI 134
Query: 147 VADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
+AD+ +R + G + A F S V P LG Y +D
Sbjct: 135 IADIVPAKDRGKYMGPLGAIFGLSAVAGPLLGGYFVD 171
>UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 492
Score = 48.8 bits (111), Expect = 3e-04
Identities = 60/314 (19%), Positives = 130/314 (41%), Gaps = 28/314 (8%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINT---WW------FFAMIS-- 131
++ + A +GA SD GRK L++ + ++ +NT W + A I
Sbjct: 90 VVPIVLALFLGAWSDRRGRKLPLILGLIGKFVYSVMIVVNTRMETWPVEYIIYTATIPSV 149
Query: 132 ISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGES--L 189
++G F+ FAY++DVTT A+R+ ++ AT+ +++ I A+G+ + + S +
Sbjct: 150 LTGADIAIFASCFAYISDVTTVADRTFRITILDATYLSTMPIGVAIGSLIYNRTARSFTI 209
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEK---VRPTGW--GPVISWEQADPFAALRKVGAER 244
+ ++ + ++ + W P +++ +L+ +R
Sbjct: 210 MFAINASLLLLSIIYSIIRLKSRTTDRQVSITELRWYRMPGDFFDKQHVVTSLKTFFKKR 269
Query: 245 TV-----LMLCVAVFLSYLPEAGQYSCIFVYLKLVMGFGVVQVAIFIAIVGVLSIGVQVI 299
T+ L + + Y + + +++Y +L + + F + V +
Sbjct: 270 TMNRRIYLYILMVAMSFYTFQRDEKPKMYLYTQLKFNWNADLYSYFKTYQSAAYV-VMMF 328
Query: 300 LG--FLMKSLGAKHT--IMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGSITYPAISA 355
LG F K L K T IM+G + Y F W+++ +++LG + P + +
Sbjct: 329 LGVPFFTKILQMKDTFIIMIGATAHAMARFVYIFAEVDWLLYVGASISSLGPVVAPVLRS 388
Query: 356 YVSVNSRADRQGVV 369
+S +G++
Sbjct: 389 MISKMVPTTERGII 402
>UniRef50_Q4ZU97 Cluster: Major facilitator superfamily; n=11;
Bacteria|Rep: Major facilitator superfamily -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 432
Score = 48.4 bits (110), Expect = 4e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 4/130 (3%)
Query: 88 SAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTI--NTWWFFAMISISGVFAVTFSIVF- 144
+A L+G +DVWGRK LL F L T + +W A+ + G+ A F +F
Sbjct: 286 AALLVGMKADVWGRKPLLLAGFLFLPIRGVLYTFSDDPYWLVAVQMLDGIGAGLFGALFP 345
Query: 145 AYVADVTTEAER-SRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXF 203
V D+T + R + + G +S F +S +L +++ G S
Sbjct: 346 LMVKDLTQGSGRFNVSLGALSTLFGLGAALSNSLAGFVVHAAGYSAAFLTLAGVAAVAFC 405
Query: 204 FIMVAVPESL 213
+ +AVPE+L
Sbjct: 406 LLWLAVPETL 415
>UniRef50_Q41AH9 Cluster: Major facilitator superfamily MFS_1; n=1;
Exiguobacterium sibiricum 255-15|Rep: Major facilitator
superfamily MFS_1 - Exiguobacterium sibiricum 255-15
Length = 408
Score = 48.4 bits (110), Expect = 4e-04
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-FT 112
+TMP ++ + + + G I+ I I S + + + G LSD +GR+ +L F F
Sbjct: 27 ITMPFFAIYLSVVLKFSPVDVGWILSISAIASLVMSFVGGTLSDRYGRRTMMLSGTFGFV 86
Query: 113 CAPIPLMTINTWW-FFAMISISGVFAVTFS-IVFAYVADVTTEAERSRAYGLVSATFAAS 170
I L + T+W FF + +++G+F F A ++D T E R + + +
Sbjct: 87 LVFIGLAQVETFWAFFILSALNGIFRSIFEPSARALISDTTEEENRLFVFNIRYTCINIA 146
Query: 171 LVISPALGAYL 181
I P + L
Sbjct: 147 AAIGPGIALLL 157
>UniRef50_O66181 Cluster: Transporter; n=1; Arthrobacter sp.|Rep:
Transporter - Arthrobacter sp
Length = 405
Score = 48.4 bits (110), Expect = 4e-04
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL-MTINTWWFFAMIS-I 132
G +M + I+S S PL GA+SD GRK LLVT+ + + + T+ F + +
Sbjct: 250 GQLMSLGSIMSIFSGPLWGAVSDKIGRKMSLLVTLLLGAVSVIIPIGFPTYLGFVICQFL 309
Query: 133 SGVFAV-TFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
G+ V S++ A + ++ A G + FA + P LG +++D +G
Sbjct: 310 WGINVVGMLSLIQALSTEQVHQSYAPVALGYTTVYFAVGQLAGPGLGGWMIDHFG 364
>UniRef50_A6CHD2 Cluster: Major facilitator family transporter; n=1;
Bacillus sp. SG-1|Rep: Major facilitator family
transporter - Bacillus sp. SG-1
Length = 539
Score = 48.4 bits (110), Expect = 4e-04
Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTV-FFTCAP-IPLMTINTWWFFAMISISGVFA-VT 139
+ S ++A L+G LSD++GRK F+L+ + FT + ++ + A I G A +
Sbjct: 56 LTSSVTAILVGKLSDMYGRKPFILIGIGVFTLGSFLNGLSGSIIELIAYRGIQGFGAGMI 115
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMD 183
S F V D+ ER R GL+S F + V P LG +++D
Sbjct: 116 MSTSFTAVGDLFAPRERGRWQGLMSGIFGLASVFGPTLGGWIVD 159
>UniRef50_A4T052 Cluster: Major facilitator superfamily MFS_1
precursor; n=2; Burkholderiaceae|Rep: Major facilitator
superfamily MFS_1 precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 394
Score = 48.4 bits (110), Expect = 4e-04
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 6/166 (3%)
Query: 54 LTMPIISVLNATFP--DHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLL--VTV 109
L +PI S+ P +H L GL +GI I+ +G LSD GRK +L +++
Sbjct: 25 LLLPIFSIHAHGLPGGEHA-LWVGLTLGIFNIVQACFYIPLGRLSDRIGRKPVVLWGLSL 83
Query: 110 FFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAA 169
F A I + W + G AV+ +I A+VAD+T E R+RA LV + A
Sbjct: 84 FIAGALICAAKDDLLWIAIGRGVMGAGAVSAAIS-AWVADLTREQVRTRAMALVGGSIAL 142
Query: 170 SLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPESLPE 215
S +S + A + S F +P S PE
Sbjct: 143 SFALSLVIAAPIYRAISLSGIFVVLAVLGVIAMFVTYYVLPTSKPE 188
>UniRef50_A3TZ27 Cluster: Drug resistance transporter, EmrB/QacA
family protein; n=3; Rhodobacteraceae|Rep: Drug
resistance transporter, EmrB/QacA family protein -
Oceanicola batsensis HTCC2597
Length = 514
Score = 48.4 bits (110), Expect = 4e-04
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVT--VFFTCAPIPLMTINTWWFFAMISISGVFAVTF 140
+ S + AP+ G L D++GRK L V VF I + + A + G+
Sbjct: 70 LASTVGAPIAGKLGDMYGRKIVLQVAIGVFLLGGLICGVARSMEVLIAGRFVQGLGGGAL 129
Query: 141 SIV-FAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
+V A VADV ER R G +S+ F S V+ P +G +L+ G
Sbjct: 130 IVVSMAVVADVLPPRERGRVQGALSSVFGFSTVVGPLIGGFLVQTVG 176
>UniRef50_P32369 Cluster: Bile acid transporter; n=2;
Clostridium|Rep: Bile acid transporter - Eubacterium sp.
(strain VPI 12708)
Length = 477
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 89 APLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFS-IVFA 145
AP++G L DV GR+ LL+ + A L + T F + + I G+ S IV A
Sbjct: 63 APILGKLGDVLGRRTTLLLGIVIFAAGNVLTAVATSLIFMLAARFIVGIGTAAISPIVMA 122
Query: 146 YVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
Y+ + E +A+GL + ++V+ P G +M+ G
Sbjct: 123 YIVTEYPQEETGKAFGLYMLISSGAVVVGPTCGGLIMNAAG 163
>UniRef50_Q9JYR7 Cluster: Drug resistance translocase family
protein; n=4; Neisseria|Rep: Drug resistance translocase
family protein - Neisseria meningitidis serogroup B
Length = 461
Score = 48.0 bits (109), Expect = 5e-04
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 54 LTMPIISVLNATFP--DHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRK--FFLLVTV 109
L +P+++V A+ P + + GL MGI G+ L +G SD +GRK + + V
Sbjct: 34 LVLPVLAVYAASLPGAEGNKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYAGLVV 93
Query: 110 FFTCAPIPLMTINTWWFFAMISISGVFAVTFSIVFAYVADVTTEAERSRAYGL----VSA 165
F + + A +I G AV+ + V A +AD+T + R+RA + +
Sbjct: 94 FAAGSFLAAAADTLPMLVAARAIQGAGAVS-AAVTALLADLTRDGVRTRAMAMIGLSIGL 152
Query: 166 TFAASLVISPAL 177
TF+ SLV++P +
Sbjct: 153 TFSVSLVVAPVI 164
>UniRef50_Q81MN1 Cluster: Drug resistance transporter, EmrB/QacA
family; n=33; Bacillaceae|Rep: Drug resistance
transporter, EmrB/QacA family - Bacillus anthracis
Length = 513
Score = 48.0 bits (109), Expect = 5e-04
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 5/149 (3%)
Query: 83 ILSFLSAPLIGALSDVWGRKFF----LLVTVFFTCAPIPLMTINTWWFFAMISISGVFAV 138
+ + P+ G LSD++GRK F L++ +F + +I + I G A+
Sbjct: 60 VATMAGMPIFGKLSDMYGRKRFYIGGLILFLFGSALCGTASSIEQLSIYRAIQGIGGGAL 119
Query: 139 TFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXX 198
I F + D+ +R + GL A F S V P LGAY+ D
Sbjct: 120 -MPIAFTIMYDIFPPEKRGKMTGLFGAVFGTSSVFGPLLGAYITDYISWHWVFYINIPLG 178
Query: 199 XXXXFFIMVAVPESLPEKVRPTGWGPVIS 227
FFI ESL + + W I+
Sbjct: 179 LISFFFITKYYSESLEFRKQKIDWAGAIT 207
>UniRef50_Q2W6Q6 Cluster: Permease of the major facilitator
superfamily; n=2; Magnetospirillum|Rep: Permease of the
major facilitator superfamily - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 424
Score = 48.0 bits (109), Expect = 5e-04
Identities = 36/125 (28%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 66 FPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPL--MTINT 123
FP+ T G+ G LS S P+ G+LSD GR+ L++ A L + +
Sbjct: 275 FPESTA---GMFWSWIGFLSLASGPVFGSLSDRIGRRAGLMIVFSCQAAAYVLVALPLPE 331
Query: 124 WWFFAMISISG--VFAVTFSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYL 181
+ +A I++ G V+AV SI+ A V D + + ++G ++ FA + PA+ ++
Sbjct: 332 PFLYASIALFGLVVWAVP-SIMAAAVGDYLGPEQAASSFGTITLIFALGQICGPAVAGWM 390
Query: 182 MDLYG 186
D +G
Sbjct: 391 ADAWG 395
>UniRef50_Q41DG4 Cluster: General substrate transporter:Major
facilitator superfamily MFS_1; n=1; Exiguobacterium
sibiricum 255-15|Rep: General substrate
transporter:Major facilitator superfamily MFS_1 -
Exiguobacterium sibiricum 255-15
Length = 415
Score = 48.0 bits (109), Expect = 5e-04
Identities = 46/190 (24%), Positives = 82/190 (43%), Gaps = 11/190 (5%)
Query: 70 TFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVF-FTCAPIPLMTINTWW-FF 127
++ + GLIM I S + L G L+D++GRK +++++ A I +++W
Sbjct: 43 SYFLVGLIMATGPITSLFGSFLGGYLADLYGRKPLMVISIVGDVIALIGFSFADSFWPLL 102
Query: 128 AMISISGVFAVTF-SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYG 186
M ++ G+ F A VADVT + ++GL+ P +G+ ++
Sbjct: 103 LMNALLGLTNSLFHPAASAMVADVTPPERLNESFGLLRMGHNVGAAFGPLIGSAVL-FID 161
Query: 187 ESLXXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTV 246
SL ++V + E+ PE++ T P +S F LRK V
Sbjct: 162 RSLIFYAAAAVFFLYALVLLVFIQETKPEQIEHTHDEPKLS-----AFTVLRK--DHVFV 214
Query: 247 LMLCVAVFLS 256
+ + VF+S
Sbjct: 215 IFIAAGVFIS 224
Score = 33.9 bits (74), Expect = 9.5
Identities = 22/114 (19%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Query: 282 VAIFIAIVGVLSIGVQVILGFLMKSLGAKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGV 341
V + +A + S+ + G+L G K +++ ++ +++ L+ + F W +
Sbjct: 47 VGLIMATGPITSLFGSFLGGYLADLYGRKPLMVISIVGDVIALIGFSFADSFWPLLLMNA 106
Query: 342 LAAL-GSITYPAISAYVSVNSRADRQGVVQGMVTGVRGLCNGLGPAMFGVIFYL 394
L L S+ +PA SA V+ + +R G++ + GP + + ++
Sbjct: 107 LLGLTNSLFHPAASAMVADVTPPERLNESFGLLRMGHNVGAAFGPLIGSAVLFI 160
>UniRef50_Q1MQW7 Cluster: Permeases of the major facilitator
superfamily; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Permeases of the major facilitator
superfamily - Lawsonia intracellularis (strain
PHE/MN1-00)
Length = 395
Score = 48.0 bits (109), Expect = 5e-04
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 6/136 (4%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV-TVFFT 112
+ +P++ +L F + T GLI+ + S L P+ G ++D++GRK LL+ F
Sbjct: 23 IILPVLPLLAHIF-ELTPTEVGLIITCFSLPSALFTPVAGIIADLYGRKKILLLGLALFA 81
Query: 113 CAPI--PLMTINTWWFFAMISISGVFAVTFSIVFA-YVADVTTEAERSRAYGLVSATFAA 169
+ L T F +I G+ A I+++ + D+ E ER + G+ AT +
Sbjct: 82 LGGVGCALSTSFKGLLFCR-AIQGLGAAPLGILYSTIIGDLYNEEERPKMMGIAGATISI 140
Query: 170 SLVISPALGAYLMDLY 185
I PALG ++ +++
Sbjct: 141 GTAIYPALGGFVGEIH 156
>UniRef50_A5FB16 Cluster: Major facilitator superfamily MFS_1
precursor; n=1; Flavobacterium johnsoniae UW101|Rep:
Major facilitator superfamily MFS_1 precursor -
Flavobacterium johnsoniae UW101
Length = 395
Score = 48.0 bits (109), Expect = 5e-04
Identities = 72/326 (22%), Positives = 125/326 (38%), Gaps = 25/326 (7%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLV--TVFFTCAPI-PLMTINTWWFFAMIS 131
G I+ + + + +S P G L+D WGR + V V C + P+++ + + F +
Sbjct: 48 GFIISLFTLTAAISRPFSGKLTDKWGRVPVMAVGSVVCLICGFLYPILSSVSGFLFLRL- 106
Query: 132 ISGVFAVTF--SIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLYGESL 189
+ G F+ F + AYVAD+ + A G+ F+ + PALG +++ YG +
Sbjct: 107 VHG-FSTGFKPTATSAYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNAYGIDV 165
Query: 190 XXXXXXXXXXXXXFFIMVAVPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLML 249
+M + E+L K + F RK + L
Sbjct: 166 MFYSSSFLAFLSIVIVM-NMKETLAAKEK----------LHKSMFYIGRKDIIDIGALPA 214
Query: 250 CVAVFLSYLPEAGQYSCIFVYL-KLVMGFGVVQVAIFIAIVGVLSIGVQVILGFLMKSLG 308
V F SY Y I + G +F + S+ V+ G + G
Sbjct: 215 GVITFFSYT----AYGLILTLIPDWSEHLGAENKGVFFTAFTIASVLVRFGAGKVSDRHG 270
Query: 309 AKHTIMVGLLFEMLQLMWYGFGSRTWMMWAAGVLAALGS-ITYPAISAYVSVNSRADRQG 367
+ I+ GL+ + L G+ ++ + +G+ I PAI+A+ S +G
Sbjct: 271 RTNVILAGLIVTSIALFVISTGNSITVLLTGAAIYGMGTGILSPAINAWTIDLSNPQHRG 330
Query: 368 VVQGMVTGVRGLCNGLGPAMFGVIFY 393
+ L GLG A+ G +Y
Sbjct: 331 KAIATMYISMELGIGLG-ALLGGSYY 355
>UniRef50_A3XKG1 Cluster: Multidrug-efflux transporter; n=2;
Flavobacteriaceae|Rep: Multidrug-efflux transporter -
Leeuwenhoekiella blandensis MED217
Length = 405
Score = 48.0 bits (109), Expect = 5e-04
Identities = 75/339 (22%), Positives = 144/339 (42%), Gaps = 19/339 (5%)
Query: 41 LVVIFLEFFAWGLL--TMPIISVLNATFPD-HTFLMN---GLIMGIKGILSFLSAPLIGA 94
L+ +F+ +G+L T+P + A + T L+N GL+ I + + + G
Sbjct: 14 LLSLFVVMLGYGILLPTLPYYTERLALKDNLDTDLINFHIGLLTSIYPLFQLIFVIVWGK 73
Query: 95 LSDVWGRKFFLLVTVF-FTCAPI--PLMTINTWWFFAMISISGVFAVT-FSIVFAYVADV 150
LSD +GRK +++ + F + L T T + A I GVF + + AY++D+
Sbjct: 74 LSDRYGRKPVIIIGLIGFVIMQLLTGLATSLTMLYIARI-FGGVFTSSVIPVSNAYLSDI 132
Query: 151 TTEAERSRAYGLVSATFAASLVISPALGAYL--MDLYGESLXXXXXXXXXXXXXFFIMVA 208
T+E R++ ++ ++ P +G +L DL+ E F +
Sbjct: 133 TSEKRRTKIMAWSGVAISSGVIFGPVIGGFLSQSDLHFEYAIGQLHLGRFSTPFLFAALL 192
Query: 209 VPESLPEKVRPTGWGPVISWEQADPFAALRKVGAERTVLMLCVAVFLSYLPEAGQYSCIF 268
L V+ I F R ++ +++L ++ + ++ + +F
Sbjct: 193 GSIVLVIVVKWLKNSVRIHKFTTQKF-TFRFSFSQYFLVLLALSFVIQFV--VTLFETVF 249
Query: 269 -VYLKLVMGFGVVQVAIFIAIVGVLSIGVQ-VILGFLMKSLGAKHTIMVGLLFEMLQLMW 326
+Y K +GF QV I + G + +Q V + K L K I GL + L+
Sbjct: 250 SIYGKDELGFNSNQVGIGFMLCGTIMAVLQPVFASYGEKILSTKKQIGFGLFISGISLIA 309
Query: 327 YGFGSRTWMMWA-AGVLAALGSITYPAISAYVSVNSRAD 364
+ F ++++ V AA G++ P + + VS+ S+ +
Sbjct: 310 FPFFKNEFVVYGLIVVFAAGGAMVTPNLLSAVSLLSKTN 348
>UniRef50_A3VM32 Cluster: Putative multidrug-efflux transporter;
n=1; Rhodobacterales bacterium HTCC2654|Rep: Putative
multidrug-efflux transporter - Rhodobacterales bacterium
HTCC2654
Length = 497
Score = 48.0 bits (109), Expect = 5e-04
Identities = 26/106 (24%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 83 ILSFLSAPLIGALSDVWGRKFFLLVTV--FFTCAPIPLMTINTWWFFAMISISGVFAV-T 139
+ S ++APL G L D++GR+ + V+V F + + + W ++ G+
Sbjct: 55 LASTIAAPLYGKLGDLYGRRNIVFVSVGLFLLGSALAGAAQSMVWLIGSRAVQGLGGGGL 114
Query: 140 FSIVFAYVADVTTEAERSRAYGLVSATFAASLVISPALGAYLMDLY 185
F + + + DV +R + G+ +ATF+ + VI P +G + ++ +
Sbjct: 115 FVLALSVIGDVIPPKDRGKTQGVFAATFSIASVIGPLIGGWFVEQF 160
>UniRef50_Q8ZT99 Cluster: Antibiotic resistance (Efflux) protein,
conjectural; n=3; Pyrobaculum|Rep: Antibiotic resistance
(Efflux) protein, conjectural - Pyrobaculum aerophilum
Length = 474
Score = 48.0 bits (109), Expect = 5e-04
Identities = 43/175 (24%), Positives = 75/175 (42%), Gaps = 8/175 (4%)
Query: 40 ALVVIFLEFFAWGLLTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVW 99
AL+V++ E + MP + + A F + T I+ I I +SA + G L D++
Sbjct: 20 ALLVMYTE-----AMLMPSLPKIQAEF-NVTPADASWILTIYLISGTISAAIFGNLGDIY 73
Query: 100 GRKFFLLVTVFFTCAPIPLMTINTWWFFAMIS--ISGVFAVTFSIVFAYVADVTTEAERS 157
G+K L + + + L + ++S I G+ F + F+ + +
Sbjct: 74 GKKRVLSLVMLAYAIAVTLTGYAPNFETLLLSRAIQGLGMAMFPLAFSLIREEFPPHMVP 133
Query: 158 RAYGLVSATFAASLVISPALGAYLMDLYGESLXXXXXXXXXXXXXFFIMVAVPES 212
A G+VSA F ++I+ +GAY+ YG F IM+ + ES
Sbjct: 134 TAQGVVSAMFGVGIIIALPVGAYIAQNYGWRATYHTATPIAVLLTFLIMIYIRES 188
>UniRef50_Q0W2N8 Cluster: Putative permease; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative permease -
Uncultured methanogenic archaeon RC-I
Length = 395
Score = 48.0 bits (109), Expect = 5e-04
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Query: 54 LTMPIISVLNATFPDHTFLMNGLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTC 113
L +PI+ T +M G+I G I L + GALSD GR+ L+ +F
Sbjct: 26 LVIPILPAYATTLGADE-MMIGVIFGAFSIALLLFSIPFGALSDRVGRRPLLVAGMFLLA 84
Query: 114 APIPLMTINTWWFFAMIS--ISGVF-AVTFSIVFAYVADVTTEAERSRAYGLVSATFAAS 170
+ I+ + +++ I G+ A T+S A +AD +ER G+ A +A
Sbjct: 85 LTNLVFVISDNLYLLIVARVIQGISGAATWSAGLALIADTFDASERGSKLGMAMAIMSAG 144
Query: 171 LVISPALGAYLMDLYG 186
+ P +G + DL G
Sbjct: 145 TLSGPVVGGIVYDLLG 160
Score = 33.9 bits (74), Expect = 9.5
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 75 GLIMGIKGILSFLSAPLIGALSDVWGRKFFLLVTVFFTCAPIPLMTINTWWFFAMISISG 134
GL G +L+ ++AP++G L D +G + L + + I L + +++ +
Sbjct: 243 GLAFGAMSLLNMVAAPVVGNLYDRFGGRGLLASGLVLSGLIIALTMLMPSMELTILAFA- 301
Query: 135 VFAVTFSIVFAYVADVTTE-------AERSRAYGLVSATFAASLVISPALGAYLM 182
+ VT S+ + + T+ + + YG+ + F+ L I P LG L+
Sbjct: 302 IVGVTMSMALTPMLPLLTDLFGGPEGSSQGFLYGIYNTLFSIGLTIGPFLGGALV 356
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.328 0.141 0.434
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 498,515,838
Number of Sequences: 1657284
Number of extensions: 20471259
Number of successful extensions: 70984
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 926
Number of HSP's that attempted gapping in prelim test: 69355
Number of HSP's gapped (non-prelim): 2039
length of query: 479
length of database: 575,637,011
effective HSP length: 104
effective length of query: 375
effective length of database: 403,279,475
effective search space: 151229803125
effective search space used: 151229803125
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 74 (33.9 bits)
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