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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000761-TA|BGIBMGA000761-PA|undefined
         (281 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D50741-1|BAA23528.1|  126|Homo sapiens Thyroid transcriptional f...    43   0.001
D50740-1|BAA23529.1|  371|Homo sapiens thyroid transcriptional f...    42   0.003
AL158013-1|CAH71494.1|  354|Homo sapiens NK2 transcription facto...    40   0.013
X82850-1|CAA58053.1|  371|Homo sapiens thyroid transcription fac...    39   0.017
U43203-1|AAA89066.1|  401|Homo sapiens thyroid transcription fac...    39   0.017
U33749-1|AAB52381.1|  371|Homo sapiens thyroid transcription fac...    39   0.017
U19816-1|AAC50125.1|  371|Homo sapiens thyroid transcription fac...    39   0.017
U19756-1|AAA86099.1|  371|Homo sapiens thyroid transcription fac...    39   0.017
BT009773-1|AAP88775.1|  401|Homo sapiens thyroid transcription f...    39   0.017
BC006221-1|AAH06221.2|  371|Homo sapiens TITF1 protein protein.        39   0.017
AF202037-1|AAG35617.1|  289|Homo sapiens homeobox transcription ...    39   0.023
D50739-1|BAA23527.1|  358|Homo sapiens thyroid transcription fac...    36   0.21 
U33627-1|AAA83233.1|   71|Homo sapiens thyroid transcription fac...    35   0.28 
AF167628-1|AAF15459.1|   89|Homo sapiens immunoglobulin heavy ch...    31   6.0  

>D50741-1|BAA23528.1|  126|Homo sapiens Thyroid transcriptional
           factor-1 truncated form protein.
          Length = 126

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 47/136 (34%), Positives = 62/136 (45%), Gaps = 28/136 (20%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R       T     +A         
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPHTAAMQQHA--------- 57

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                  P    A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 58  ----VGHPGAVTAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRFANNK 169
            GWY A+ DPRF  +K
Sbjct: 111 PGWYGANPDPRFPASK 126


>D50740-1|BAA23529.1|  371|Homo sapiens thyroid transcriptional
           factor-1 protein.
          Length = 371

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R       T     +A         
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPHTAAMQQHA--------- 57

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                  P    A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 58  ----VGHPGAVTAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>AL158013-1|CAH71494.1|  354|Homo sapiens NK2 transcription factor
           related, locus 4 (Drosophila) protein.
          Length = 354

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 45/142 (31%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 46  HSTPFSVTDILSPIEE-YRKLELANN--PP---SPYRAHRTAYDVK---ATDDFIDYAQL 96
           H+TPFSV+DILSPIEE Y+K   A +  PP   +P  A   AY       +      A +
Sbjct: 7   HTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGA-AAAYRAPPPGPSSQAATVAGM 65

Query: 97  SVDRXXXXXXXXXXPLGPAASCGMTANPYAVPLYGGAP--VQGYGC-----APTDLPHYG 149
                             AA+    A  +  P     P    G  C        +LP Y 
Sbjct: 66  QPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGELPAYT 125

Query: 150 D-MRG---AGWYPASNDPRFAN 167
           D MRG    GWY A+ DPR+++
Sbjct: 126 DGMRGGAATGWYGANPDPRYSS 147


>X82850-1|CAA58053.1|  371|Homo sapiens thyroid transcription factor
           1 protein.
          Length = 371

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 63

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 64  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>U43203-1|AAA89066.1|  401|Homo sapiens thyroid transcription factor
           1 protein.
          Length = 401

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 37  HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 93

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 94  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 140

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 141 PGWYGANPDPRF 152


>U33749-1|AAB52381.1|  371|Homo sapiens thyroid transcription
           factor-1 protein.
          Length = 371

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 63

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 64  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>U19816-1|AAC50125.1|  371|Homo sapiens thyroid transcription
           factor-1 protein.
          Length = 371

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 63

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 64  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>U19756-1|AAA86099.1|  371|Homo sapiens thyroid transcription factor
           1 protein.
          Length = 371

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 63

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 64  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>BT009773-1|AAP88775.1|  401|Homo sapiens thyroid transcription
           factor 1 protein.
          Length = 401

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 37  HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 93

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 94  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 140

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 141 PGWYGANPDPRF 152


>BC006221-1|AAH06221.2|  371|Homo sapiens TITF1 protein protein.
          Length = 371

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 46/132 (34%), Positives = 61/132 (46%), Gaps = 28/132 (21%)

Query: 46  HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHRTAYDVKATDDFIDYAQLSVDRXXX 103
           H+TPFSV+DILSP+EE Y+K+ +      +P  A+R     +A        Q +V     
Sbjct: 7   HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG---QAAPPTAAMQQHAVGHHGA 63

Query: 104 XXXXXXXPLGPAASCGMTANPYAVPLYGGAPVQGYGC-----APTDLPHYGD-MR----G 153
                       A+  MTA    VP    + V GY C       ++LP Y D MR    G
Sbjct: 64  V----------TAAYHMTA--AGVPQLSHSAVGGY-CNGNLGNMSELPPYQDTMRNSASG 110

Query: 154 AGWYPASNDPRF 165
            GWY A+ DPRF
Sbjct: 111 PGWYGANPDPRF 122


>AF202037-1|AAG35617.1|  289|Homo sapiens homeobox transcription
           factor protein.
          Length = 289

 Score = 38.7 bits (86), Expect = 0.023
 Identities = 46/142 (32%), Positives = 62/142 (43%), Gaps = 21/142 (14%)

Query: 46  HSTPFSVTDILSPIEE-YRKLELANN--PP---SPYRAHRTAYDVKATDDFIDYAQLS-- 97
           H+TPFSV+DILSPIEE Y+K   A +  PP   +P  A   AY           A ++  
Sbjct: 7   HTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGA-AAAYRAPPPGPSSQAATVAGM 65

Query: 98  VDRXXXXXXXXXXPLGPAASCGMTANPYAVPL------YG--GAPVQGYGCAPTDLPHYG 149
                            AA+    A  Y +P       +G  G+   G      +LP Y 
Sbjct: 66  QPSHAMAGHNAAAAAAAAAAAAAAAATYHMPAGVSQFPHGAMGSYCNGGLGNMGELPAYT 125

Query: 150 D-MRG---AGWYPASNDPRFAN 167
           D MRG    GWY A+ DPR+++
Sbjct: 126 DGMRGGAATGWYGANPDPRYSS 147


>D50739-1|BAA23527.1|  358|Homo sapiens thyroid transcription
          factor-1 protein.
          Length = 358

 Score = 35.5 bits (78), Expect = 0.21
 Identities = 18/36 (50%), Positives = 26/36 (72%), Gaps = 2/36 (5%)

Query: 46 HSTPFSVTDILSPIEE-YRKLEL-ANNPPSPYRAHR 79
          H+TPFSV+DILSP+EE Y+K+ +      +P  A+R
Sbjct: 7  HTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYR 42


>U33627-1|AAA83233.1|   71|Homo sapiens thyroid transcription
          factor-1 protein.
          Length = 71

 Score = 35.1 bits (77), Expect = 0.28
 Identities = 15/21 (71%), Positives = 20/21 (95%), Gaps = 1/21 (4%)

Query: 46 HSTPFSVTDILSPIEE-YRKL 65
          H+TPFSV+DILSP+EE Y+K+
Sbjct: 37 HTTPFSVSDILSPLEESYKKV 57


>AF167628-1|AAF15459.1|   89|Homo sapiens immunoglobulin heavy chain
           variable region protein.
          Length = 89

 Score = 30.7 bits (66), Expect = 6.0
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 198 TVRVVNYCTTESLQLSRLTAIEARRFPINCARYIRYNVFTGHPRGDAQYLY 248
           T+   N   T  LQ++ L A +   +   CAR I Y+ ++G+P+G A Y Y
Sbjct: 34  TISRDNSKNTLYLQMNSLRAEDTAVY--YCARSIYYDFWSGYPQGRAYYYY 82


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.321    0.138    0.440 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 38,981,930
Number of Sequences: 224733
Number of extensions: 1538791
Number of successful extensions: 2303
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2279
Number of HSP's gapped (non-prelim): 25
length of query: 281
length of database: 73,234,838
effective HSP length: 89
effective length of query: 192
effective length of database: 53,233,601
effective search space: 10220851392
effective search space used: 10220851392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 65 (30.3 bits)

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