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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000760-TA|BGIBMGA000760-PA|IPR002345|Lipocalin,
IPR006592|RNA polymerase I subunit A, N-terminal, IPR007080|RNA
polymerase Rpb1, domain 1, IPR000722|RNA polymerase, alpha subunit,
IPR007066|RNA polymerase Rpb1, domain 3, IPR007083|RNA polymerase
Rpb1, domain 4, IPR007081|RNA polymerase Rpb1, domain 5
         (1191 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC041089-1|AAH41089.1| 1390|Homo sapiens polymerase (RNA) III (D...  1439   0.0  
AL512628-1|CAI16466.1| 1390|Homo sapiens polymerase (RNA) III (D...  1439   0.0  
AF021351-1|AAB86536.1| 1391|Homo sapiens RNA polymerase III larg...  1434   0.0  
X74874-1|CAA52862.1| 1970|Homo sapiens RNA polymerase II largest...   588   e-167
X63564-1|CAA45125.1| 1970|Homo sapiens RNA polymerase II largest...   588   e-167
AY091460-1|AAM12030.1|  387|Homo sapiens RNA polymerase III subu...   555   e-157
AY091461-1|AAM12031.1|  435|Homo sapiens RNA polymerase III subu...   472   e-132
AY091459-1|AAM12029.1|  374|Homo sapiens RNA polymerase III subu...   468   e-131
BC126303-1|AAI26304.1| 1720|Homo sapiens polymerase (RNA) I poly...   359   4e-98
BC117173-1|AAI17174.1| 1720|Homo sapiens polymerase (RNA) I poly...   359   4e-98
BC073968-1|AAH73968.1| 1032|Homo sapiens POLR1A protein protein.      359   4e-98
U33460-1|AAC99959.1| 1717|Homo sapiens DNA-directed RNA polymera...   355   5e-97
BC067295-1|AAH67295.1|  566|Homo sapiens POLR2A protein protein.      343   2e-93
AC012511-1|AAY24277.1|  922|Homo sapiens unknown protein.             157   2e-37
U33823-1|AAD09356.1|  441|Homo sapiens DNA-directed RNA polymera...   123   3e-27
BC017115-1|AAH17115.2|  574|Homo sapiens POLR1A protein protein.       93   7e-18
AY091462-1|AAM12032.1|  299|Homo sapiens RNA polymerase III subu...    58   2e-07
M21610-1|AAA60135.1|  113|Homo sapiens POLR2 protein.                  57   4e-07
AK025568-1|BAB15171.1|  495|Homo sapiens protein ( Homo sapiens ...    52   9e-06
BC014399-1|AAH14399.1|  162|Homo sapiens POLR3A protein protein.       38   0.16 
AF187991-1|AAF04107.1|  706|Homo sapiens zinc finger protein ZNF...    35   1.5  
BC108912-1|AAI08913.1|  706|Homo sapiens zinc finger protein 225...    34   2.7  
AK223477-1|BAD97197.1|  706|Homo sapiens zinc finger protein 225...    34   2.7  
AC074331-1|AAF88105.1|  628|Homo sapiens ZNF225 [amino acids 79-...    34   2.7  
AC021092-2|AAF24967.1|  706|Homo sapiens ZNF225 protein.               34   2.7  

>BC041089-1|AAH41089.1| 1390|Homo sapiens polymerase (RNA) III (DNA
            directed) polypeptide A, 155kDa protein.
          Length = 1390

 Score = 1439 bits (3567), Expect = 0.0
 Identities = 700/1124 (62%), Positives = 852/1124 (75%), Gaps = 27/1124 (2%)

Query: 1    MPKEQYRETYVGRKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRM 60
            M KEQ+RET V +KISH+ F + SP  ++Q AHI+V++KNL+ QD Q  P  +GVLD RM
Sbjct: 1    MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM 60

Query: 61   GTNQKDANCETCGLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPES 120
            GT++KD  CETCG  LA+C+GH+GYI L LP FHVGYFRA+I ILQ ICK C  +ML + 
Sbjct: 61   GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE 120

Query: 121  LKKSYRRKFINPEMSYLLKKNLKAVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVHEK 180
             KK +      P ++YL K+ LK  +  K +  + C  C A NG VKK   G+LKI+HEK
Sbjct: 121  EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKC--GLLKIIHEK 178

Query: 181  YRA-KKPTDPIVKKVLMDFHEAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPL 239
            Y+  KK  DPIV   L  F  A E NKEV  ++     + ++PL VLNLF+RIP ED+PL
Sbjct: 179  YKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQ-ENLNPLVVLNLFKRIPAEDVPL 237

Query: 240  LGMNVKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHL 299
            L MN +  +P DLILTRL VPPLCIRPSVVSD+K+GTNEDDLTMK +EI+ +NDVI +H 
Sbjct: 238  LLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHR 297

Query: 300  ASAGKCELIQEDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLS 359
             S  K ++I EDWD+LQL  ALYINSE+SGIPL M PKK  RG VQRLKGKQGRFRGNLS
Sbjct: 298  ISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLS 357

Query: 360  GKRVDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPG 419
            GKRVDFS RTVISPDPNL+I EV VPVHVAKILT+PE+V  AN+ +LR+LV NGP+VHPG
Sbjct: 358  GKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPG 417

Query: 420  ANYVQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHR 479
            AN++QQR  + K++LKYGNREK+AQELK GD+VERHL+DGDVVLFNRQPSLHKLSIM H 
Sbjct: 418  ANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHL 477

Query: 480  AKVQPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVS 539
            A+V+P RTFRFNECVCTPYNADFDGDEMN+HLPQTEEA+AEAL+LMG+            
Sbjct: 478  ARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGT------------ 525

Query: 540  LEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRI 599
                K+NLVTPRNGE LIAA QDF+TG YL+T +DTFF +++A Q+ A +L G D  +++
Sbjct: 526  ----KANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKV 581

Query: 600  DMPPPAIIKPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGN-KDLCVQDSYVIIR 658
             +PPP I+KP  LWTGKQIFS+I+RP+    V+ANL TKGK Y G  +DLC  DSYV I+
Sbjct: 582  RLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQ 641

Query: 659  NSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGII 718
            NSEL+ GSMDK TLGSG+K++IFYILLRDWG+  A   M RLAR+A  Y+ NRGFS GI 
Sbjct: 642  NSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIG 701

Query: 719  DVTPGKKLIEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAVMLSELSSIRE 778
            DVTPG+ L++AK +LL +GY KCD YI  +  G LQ QPGCT EETLEA++L ELS IR+
Sbjct: 702  DVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRD 761

Query: 779  LAAKACFRELHPTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHF 838
             A  AC REL  +N+PL MA  GSKGS INISQMIACVGQQA++G RVP+GFE+RSLPHF
Sbjct: 762  HAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHF 821

Query: 839  ERHSKIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLED 898
            E+HSK+PAA+GFV NSFY+GLTPTEFFFHTM GREGLVDTAVKTAETGY+QRRLVKSLED
Sbjct: 822  EKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLED 881

Query: 899  LVLQYDMTVRNATGEVVQFRYGSDGLDPTYMEGKDRPVDLARVLADVRAKCQDKNAEPLD 958
            L  QYD+TVR++TG+++QF YG DGLDP  MEGKD P++  RVL +++A     +   L 
Sbjct: 882  LCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALS 941

Query: 959  GDGIVLAAEETLALDDFKTSTDEFKNELLSFLKATAGRVRALRARYA----GC--GRAAL 1012
             + ++L  E  +   +F    D F  E+  F+K  + +++  R +Y     G    R   
Sbjct: 942  KNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLY 1001

Query: 1013 QLERLTLTQLVRFLRVCHHKYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASM 1072
            QL+R+T TQ+ +FL  C  KY R  +EPG+AVGAL AQSIGEPGTQMTLKTFHFAGVASM
Sbjct: 1002 QLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASM 1061

Query: 1073 NITQGVPRVKEIINASRNISTPIITAELMQPYDQEFARRVKGRI 1116
            NIT GVPR+KEIINAS+ ISTPIITA+L +  D ++AR VKGRI
Sbjct: 1062 NITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRI 1105



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/77 (48%), Positives = 46/77 (59%), Gaps = 3/77 (3%)

Query: 1109 ARRVKGRICTSKLKVKPAEVTAVSAWAIKVTG-EPSKSCGWLNMSLQQLGRQLPAVVVKG 1167
            A  V+  ICTSKL+VKP +V       + VT  E SKS   +   LQ L   LP VVV+G
Sbjct: 1146 AETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSS--MYYVLQFLKEDLPKVVVQG 1203

Query: 1168 LPQVSRAVIACDDSSEK 1184
            +P+VSRAVI  D+ S K
Sbjct: 1204 IPEVSRAVIHIDEQSGK 1220


>AL512628-1|CAI16466.1| 1390|Homo sapiens polymerase (RNA) III (DNA
            directed) (155kD) (RPC155) protein.
          Length = 1390

 Score = 1439 bits (3567), Expect = 0.0
 Identities = 700/1124 (62%), Positives = 852/1124 (75%), Gaps = 27/1124 (2%)

Query: 1    MPKEQYRETYVGRKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRM 60
            M KEQ+RET V +KISH+ F + SP  ++Q AHI+V++KNL+ QD Q  P  +GVLD RM
Sbjct: 1    MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM 60

Query: 61   GTNQKDANCETCGLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPES 120
            GT++KD  CETCG  LA+C+GH+GYI L LP FHVGYFRA+I ILQ ICK C  +ML + 
Sbjct: 61   GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE 120

Query: 121  LKKSYRRKFINPEMSYLLKKNLKAVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVHEK 180
             KK +      P ++YL K+ LK  +  K +  + C  C A NG VKK   G+LKI+HEK
Sbjct: 121  EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKC--GLLKIIHEK 178

Query: 181  YRA-KKPTDPIVKKVLMDFHEAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPL 239
            Y+  KK  DPIV   L  F  A E NKEV  ++     + ++PL VLNLF+RIP ED+PL
Sbjct: 179  YKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQ-ENLNPLVVLNLFKRIPAEDVPL 237

Query: 240  LGMNVKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHL 299
            L MN +  +P DLILTRL VPPLCIRPSVVSD+K+GTNEDDLTMK +EI+ +NDVI +H 
Sbjct: 238  LLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHR 297

Query: 300  ASAGKCELIQEDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLS 359
             S  K ++I EDWD+LQL  ALYINSE+SGIPL M PKK  RG VQRLKGKQGRFRGNLS
Sbjct: 298  ISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLS 357

Query: 360  GKRVDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPG 419
            GKRVDFS RTVISPDPNL+I EV VPVHVAKILT+PE+V  AN+ +LR+LV NGP+VHPG
Sbjct: 358  GKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPG 417

Query: 420  ANYVQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHR 479
            AN++QQR  + K++LKYGNREK+AQELK GD+VERHL+DGDVVLFNRQPSLHKLSIM H 
Sbjct: 418  ANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHL 477

Query: 480  AKVQPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVS 539
            A+V+P RTFRFNECVCTPYNADFDGDEMN+HLPQTEEA+AEAL+LMG+            
Sbjct: 478  ARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGT------------ 525

Query: 540  LEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRI 599
                K+NLVTPRNGE LIAA QDF+TG YL+T +DTFF +++A Q+ A +L G D  +++
Sbjct: 526  ----KANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKV 581

Query: 600  DMPPPAIIKPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGN-KDLCVQDSYVIIR 658
             +PPP I+KP  LWTGKQIFS+I+RP+    V+ANL TKGK Y G  +DLC  DSYV I+
Sbjct: 582  RLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQ 641

Query: 659  NSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGII 718
            NSEL+ GSMDK TLGSG+K++IFYILLRDWG+  A   M RLAR+A  Y+ NRGFS GI 
Sbjct: 642  NSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIG 701

Query: 719  DVTPGKKLIEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAVMLSELSSIRE 778
            DVTPG+ L++AK +LL +GY KCD YI  +  G LQ QPGCT EETLEA++L ELS IR+
Sbjct: 702  DVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRD 761

Query: 779  LAAKACFRELHPTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHF 838
             A  AC REL  +N+PL MA  GSKGS INISQMIACVGQQA++G RVP+GFE+RSLPHF
Sbjct: 762  HAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHF 821

Query: 839  ERHSKIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLED 898
            E+HSK+PAA+GFV NSFY+GLTPTEFFFHTM GREGLVDTAVKTAETGY+QRRLVKSLED
Sbjct: 822  EKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLED 881

Query: 899  LVLQYDMTVRNATGEVVQFRYGSDGLDPTYMEGKDRPVDLARVLADVRAKCQDKNAEPLD 958
            L  QYD+TVR++TG+++QF YG DGLDP  MEGKD P++  RVL +++A     +   L 
Sbjct: 882  LCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALS 941

Query: 959  GDGIVLAAEETLALDDFKTSTDEFKNELLSFLKATAGRVRALRARYA----GC--GRAAL 1012
             + ++L  E  +   +F    D F  E+  F+K  + +++  R +Y     G    R   
Sbjct: 942  KNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLY 1001

Query: 1013 QLERLTLTQLVRFLRVCHHKYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASM 1072
            QL+R+T TQ+ +FL  C  KY R  +EPG+AVGAL AQSIGEPGTQMTLKTFHFAGVASM
Sbjct: 1002 QLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASM 1061

Query: 1073 NITQGVPRVKEIINASRNISTPIITAELMQPYDQEFARRVKGRI 1116
            NIT GVPR+KEIINAS+ ISTPIITA+L +  D ++AR VKGRI
Sbjct: 1062 NITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRI 1105



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/77 (48%), Positives = 46/77 (59%), Gaps = 3/77 (3%)

Query: 1109 ARRVKGRICTSKLKVKPAEVTAVSAWAIKVTG-EPSKSCGWLNMSLQQLGRQLPAVVVKG 1167
            A  V+  ICTSKL+VKP +V       + VT  E SKS   +   LQ L   LP VVV+G
Sbjct: 1146 AETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSS--MYYVLQFLKEDLPKVVVQG 1203

Query: 1168 LPQVSRAVIACDDSSEK 1184
            +P+VSRAVI  D+ S K
Sbjct: 1204 IPEVSRAVIHIDEQSGK 1220


>AF021351-1|AAB86536.1| 1391|Homo sapiens RNA polymerase III largest
            subunit protein.
          Length = 1391

 Score = 1434 bits (3554), Expect = 0.0
 Identities = 697/1124 (62%), Positives = 849/1124 (75%), Gaps = 27/1124 (2%)

Query: 1    MPKEQYRETYVGRKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRM 60
            M KEQ+RET V +K SH+ F + SP  ++Q AHI+V++KNL+ QD Q  P  +GVLD RM
Sbjct: 1    MVKEQFRETDVAKKTSHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM 60

Query: 61   GTNQKDANCETCGLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPES 120
            GT++KD  CETCG  LA+C+GH+GYI L LP FHVGYFRA+I ILQ ICK C  +ML + 
Sbjct: 61   GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE 120

Query: 121  LKKSYRRKFINPEMSYLLKKNLKAVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVHEK 180
             KK +      P ++YL K+ LK  +  K +  + C  C A NG VKK   G+LKI+HEK
Sbjct: 121  EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKC--GLLKIIHEK 178

Query: 181  YRA-KKPTDPIVKKVLMDFHEAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPL 239
            Y+  KK  DPIV   L  F  A E NKEV  ++     + ++PL VLNLF+RIP ED+PL
Sbjct: 179  YKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQ-ENLNPLVVLNLFKRIPAEDVPL 237

Query: 240  LGMNVKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHL 299
            L MN +  +P DLILTRL VPPLC RPSVVSD+K+GTNEDDLTMK +EI+ +NDVI +H 
Sbjct: 238  LLMNPEAGKPSDLILTRLLVPPLCFRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHR 297

Query: 300  ASAGKCELIQEDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLS 359
             S  K ++I EDWD+LQL  ALYINSE+SGIPL M PKK  RG VQRLKGKQGRFRGNLS
Sbjct: 298  ISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLS 357

Query: 360  GKRVDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPG 419
            GKRVDFS RTVISPDPNL+I EV VPVHVAKILT+PE+V  AN+ +LR+LV NGP+VHPG
Sbjct: 358  GKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPG 417

Query: 420  ANYVQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHR 479
            AN++QQR  + K++LKYGNREK+AQELK GD+VERHL+DGDVVLFNRQPSLHKLSIM H 
Sbjct: 418  ANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHL 477

Query: 480  AKVQPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVS 539
            A+V+P RTFRFNECVCTPYNADFDGDEMN+HLPQTEEA+AEAL+LMG+            
Sbjct: 478  ARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGT------------ 525

Query: 540  LEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRI 599
                K+NLVTPRNGE LIAA QDF+TG YL+T +DTFF +++A Q+ A +L G D  +++
Sbjct: 526  ----KANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKV 581

Query: 600  DMPPPAIIKPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGN-KDLCVQDSYVIIR 658
             +PPP I+KP  LWTGKQIFS+I+RP+    V+ANL TKGK Y G  +DLC  DSYV I+
Sbjct: 582  RLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQ 641

Query: 659  NSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGII 718
            NSEL+ GSMDK TLGSG+K++IFYILLRDWG+  A   M RLAR+A  Y+ NRGFS GI 
Sbjct: 642  NSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIG 701

Query: 719  DVTPGKKLIEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAVMLSELSSIRE 778
            DVTPG+ L++AK +LL +GY KCD YI  +  G LQ QPGCT EETLEA++L ELS IR+
Sbjct: 702  DVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRD 761

Query: 779  LAAKACFRELHPTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHF 838
             A  AC REL  +N+PL MA  GSKGS INISQMIACVGQQA++G RVP+GFE+RSLPHF
Sbjct: 762  HAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHF 821

Query: 839  ERHSKIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLED 898
            E+HSK+PAA+GFV NSFY+GLTPTEFFFHTM GREGLVDTAVKTAETGY+QRRLVKSLED
Sbjct: 822  EKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLED 881

Query: 899  LVLQYDMTVRNATGEVVQFRYGSDGLDPTYMEGKDRPVDLARVLADVRAKCQDKNAEPLD 958
            L  QYD+TVR++TG+++QF YG DGLDP  MEGKD P++  RVL +++A     +   L 
Sbjct: 882  LCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALS 941

Query: 959  GDGIVLAAEETLALDDFKTSTDEFKNELLSFLKATAGRVRALRARYA----GC--GRAAL 1012
             + ++L  E  +   +F    D F  E+  F+K  + +++  R +Y     G    R   
Sbjct: 942  KNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLY 1001

Query: 1013 QLERLTLTQLVRFLRVCHHKYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASM 1072
            QL+R+T TQ+ +FL  C  KY R  +EPG+AVGAL AQSIGEPGTQMTLKTFHF GVASM
Sbjct: 1002 QLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFGGVASM 1061

Query: 1073 NITQGVPRVKEIINASRNISTPIITAELMQPYDQEFARRVKGRI 1116
            NIT GVPR+KEIINAS+ ISTPIITA+L +  D ++AR VKGRI
Sbjct: 1062 NITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRI 1105



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/77 (48%), Positives = 46/77 (59%), Gaps = 3/77 (3%)

Query: 1109 ARRVKGRICTSKLKVKPAEVTAVSAWAIKVTG-EPSKSCGWLNMSLQQLGRQLPAVVVKG 1167
            A  V+  ICTSKL+VKP +V       + VT  E SKS   +   LQ L   LP VVV+G
Sbjct: 1146 AETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSS--MYYVLQFLKEDLPKVVVQG 1203

Query: 1168 LPQVSRAVIACDDSSEK 1184
            +P+VSRAVI  D+ S K
Sbjct: 1204 IPEVSRAVIHIDEQSGK 1220


>X74874-1|CAA52862.1| 1970|Homo sapiens RNA polymerase II largest
           subunit protein.
          Length = 1970

 Score =  588 bits (1453), Expect = e-167
 Identities = 352/922 (38%), Positives = 518/922 (56%), Gaps = 51/922 (5%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R I  V F V SP  +++ +  E   K     +G R P   G++D R G  ++   C+TC
Sbjct: 16  RTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGR-PKLGGLMDPRQGVIERTGRCQTC 74

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINP 132
              + EC GHFG+I+L  PVFHVG+    + +L+ +C  C+K+++  +          NP
Sbjct: 75  AGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSN----------NP 124

Query: 133 EMSYLLKKNLKAVVHKKAKTFSKCPS---CEAINGMVKKSSI----GILKIVHEK-YRAK 184
           ++  +L K+      +    +  C     CE    M  K  +    G   +  EK +   
Sbjct: 125 KIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGC 184

Query: 185 KPTDPIVKKVLMDFH-EAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPLLGMN 243
               P +++  ++ + E K  N++        ++  +SP  V  +F+RI DE+  +LGM 
Sbjct: 185 GRYQPRIRRSGLELYAEWKHVNEDSQ---EKKIL--LSPERVHEIFKRISDEECFVLGME 239

Query: 244 VKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAG 303
            + +RPE +I+T LPVPPL +RP+VV    A  N+DDLT K ++I+ IN+ + R+  +  
Sbjct: 240 PRYARPEWMIVTVLPVPPLSVRPAVVMQGSA-RNQDDLTHKLADIVKINNQLRRNEQNGA 298

Query: 304 KCELIQEDWDYLQLHAALYINSEMSGIPLAMQPK-KPGRGLVQRLKGKQGRFRGNLSGKR 362
              +I ED   LQ H A  +++E+ G+P AMQ   +P + L QRLKGK+GR RGNL GKR
Sbjct: 299 AAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKR 358

Query: 363 VDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANY 422
           VDFS+RTVI+PDPNL I +VGVP  +A  +T+ E V P N+  L+ LV  G   +PGA Y
Sbjct: 359 VDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKY 418

Query: 423 VQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHRAKV 482
           +  R    +  L++  +      L+ G  VERH+ DGD+V+FNRQP+LHK+S+M HR ++
Sbjct: 419 II-RDNGDRIDLRFHPKPSDLH-LQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRI 476

Query: 483 QPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVSLEQ 542
            P  TFR N  V TPYNADFDGDEMN+HLPQ+ E RAE           + ++ R+    
Sbjct: 477 LPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEI--------QELAMVPRM---- 524

Query: 543 NKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRIDMP 602
               +VTP++   ++   QD +T     T+RD F  + E   L   L     +T    +P
Sbjct: 525 ----IVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFL-----STWDGKVP 575

Query: 603 PPAIIKPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGNKDLCVQDSYVIIRNSEL 662
            PAI+KPR LWTGKQIFSLI+  +  C    +     ++    K +   D+ V++ N EL
Sbjct: 576 QPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGEL 635

Query: 663 VCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGIIDVTP 722
           + G + K +LG+ +  S+ +I   + G +        +  + + +++  G + GI D   
Sbjct: 636 IMGILCKKSLGT-SAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIA 694

Query: 723 GKKLIEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAVMLSELSSIRELAAK 782
             K  +     ++         I +     L+  PG T+ +T E  +   L+  R+    
Sbjct: 695 DSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGS 754

Query: 783 ACFRELHPTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHS 842
           +  + L   N    M  SG+KGS INISQ+IA VGQQ + GKR+P GF+ R+LPHF +  
Sbjct: 755 SAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDD 814

Query: 843 KIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQ 902
             P +RGFVENS+  GLTPTEFFFH MGGREGL+DTAVKTAETGY+QRRL+KS+E ++++
Sbjct: 815 YGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVK 874

Query: 903 YDMTVRNATGEVVQFRYGSDGL 924
           YD TVRN+  +VVQ RYG DGL
Sbjct: 875 YDATVRNSINQVVQLRYGEDGL 896



 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 49/111 (44%), Positives = 67/111 (60%), Gaps = 1/111 (0%)

Query: 1007 CGRAALQLERLTLTQLVRFLRVCHHKYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHF 1066
            C R   +  RL+       L     K+ + +  PG  VGALAAQS+GEP TQMTL TFH+
Sbjct: 1050 CSRRMAEEFRLSGEAFDLLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHY 1109

Query: 1067 AGVASMNITQGVPRVKEIINASRNISTPIITAELMQPYDQEFARRVKGRIC 1117
            AGV++ N+T GVPR+KE+IN S+   TP +T  L+    ++ A R K  +C
Sbjct: 1110 AGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARD-AERAKDILC 1159


>X63564-1|CAA45125.1| 1970|Homo sapiens RNA polymerase II largest
           subunit protein.
          Length = 1970

 Score =  588 bits (1453), Expect = e-167
 Identities = 352/922 (38%), Positives = 518/922 (56%), Gaps = 51/922 (5%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R I  V F V SP  +++ +  E   K     +G R P   G++D R G  ++   C+TC
Sbjct: 16  RTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGR-PKLGGLMDPRQGVIERTGRCQTC 74

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINP 132
              + EC GHFG+I+L  PVFHVG+    + +L+ +C  C+K+++  +          NP
Sbjct: 75  AGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSN----------NP 124

Query: 133 EMSYLLKKNLKAVVHKKAKTFSKCPS---CEAINGMVKKSSI----GILKIVHEK-YRAK 184
           ++  +L K+      +    +  C     CE    M  K  +    G   +  EK +   
Sbjct: 125 KIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGC 184

Query: 185 KPTDPIVKKVLMDFH-EAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPLLGMN 243
               P +++  ++ + E K  N++        ++  +SP  V  +F+RI DE+  +LGM 
Sbjct: 185 GRYQPRIRRSGLELYAEWKHVNEDSQ---EKKIL--LSPERVHEIFKRISDEECFVLGME 239

Query: 244 VKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAG 303
            + +RPE +I+T LPVPPL +RP+VV    A  N+DDLT K ++I+ IN+ + R+  +  
Sbjct: 240 PRYARPEWMIVTVLPVPPLSVRPAVVMQGSA-RNQDDLTHKLADIVKINNQLRRNEQNGA 298

Query: 304 KCELIQEDWDYLQLHAALYINSEMSGIPLAMQPK-KPGRGLVQRLKGKQGRFRGNLSGKR 362
              +I ED   LQ H A  +++E+ G+P AMQ   +P + L QRLKGK+GR RGNL GKR
Sbjct: 299 AAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKR 358

Query: 363 VDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANY 422
           VDFS+RTVI+PDPNL I +VGVP  +A  +T+ E V P N+  L+ LV  G   +PGA Y
Sbjct: 359 VDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKY 418

Query: 423 VQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHRAKV 482
           +  R    +  L++  +      L+ G  VERH+ DGD+V+FNRQP+LHK+S+M HR ++
Sbjct: 419 II-RDNGDRIDLRFHPKPSDLH-LQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRI 476

Query: 483 QPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVSLEQ 542
            P  TFR N  V TPYNADFDGDEMN+HLPQ+ E RAE           + ++ R+    
Sbjct: 477 LPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEI--------QELAMVPRM---- 524

Query: 543 NKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRIDMP 602
               +VTP++   ++   QD +T     T+RD F  + E   L   L     +T    +P
Sbjct: 525 ----IVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFL-----STWDGKVP 575

Query: 603 PPAIIKPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGNKDLCVQDSYVIIRNSEL 662
            PAI+KPR LWTGKQIFSLI+  +  C    +     ++    K +   D+ V++ N EL
Sbjct: 576 QPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGEL 635

Query: 663 VCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGIIDVTP 722
           + G + K +LG+ +  S+ +I   + G +        +  + + +++  G + GI D   
Sbjct: 636 IMGILCKKSLGT-SAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIA 694

Query: 723 GKKLIEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAVMLSELSSIRELAAK 782
             K  +     ++         I +     L+  PG T+ +T E  +   L+  R+    
Sbjct: 695 DSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGS 754

Query: 783 ACFRELHPTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHS 842
           +  + L   N    M  SG+KGS INISQ+IA VGQQ + GKR+P GF+ R+LPHF +  
Sbjct: 755 SAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDD 814

Query: 843 KIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQ 902
             P +RGFVENS+  GLTPTEFFFH MGGREGL+DTAVKTAETGY+QRRL+KS+E ++++
Sbjct: 815 YGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVK 874

Query: 903 YDMTVRNATGEVVQFRYGSDGL 924
           YD TVRN+  +VVQ RYG DGL
Sbjct: 875 YDATVRNSINQVVQLRYGEDGL 896



 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 49/111 (44%), Positives = 67/111 (60%), Gaps = 1/111 (0%)

Query: 1007 CGRAALQLERLTLTQLVRFLRVCHHKYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHF 1066
            C R   +  RL+       L     K+ + +  PG  VGALAAQS+GEP TQMTL TFH+
Sbjct: 1050 CSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHY 1109

Query: 1067 AGVASMNITQGVPRVKEIINASRNISTPIITAELMQPYDQEFARRVKGRIC 1117
            AGV++ N+T GVPR+KE+IN S+   TP +T  L+    ++ A R K  +C
Sbjct: 1110 AGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARD-AERAKDILC 1159


>AY091460-1|AAM12030.1|  387|Homo sapiens RNA polymerase III subunit
           RPC155-B protein.
          Length = 387

 Score =  555 bits (1370), Expect = e-157
 Identities = 265/402 (65%), Positives = 320/402 (79%), Gaps = 17/402 (4%)

Query: 368 RTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANYVQQRG 427
           RTVISPDPNL+I EV VPVHVAKILT+PE+V  AN+ +LR+LV NGP+VHPGAN++QQR 
Sbjct: 2   RTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRH 61

Query: 428 LKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHRAKVQPQRT 487
            + K++LKYGNREK+AQELK GD+VERHL+DGDVVLFNRQPSLHKLSIM H A+V+P RT
Sbjct: 62  TQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRT 121

Query: 488 FRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVSLEQNKSNL 547
           FRFNECVCTPYNADFDGDEMN+HLPQTEEA+AEAL+LMG+                K+NL
Sbjct: 122 FRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGT----------------KANL 165

Query: 548 VTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDATMRIDMPPPAII 607
           VTPRNGE LIAA QDF+TG YL+T +DTFF +++A Q+ A +L G D  +++ +PPP I+
Sbjct: 166 VTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTIL 225

Query: 608 KPRKLWTGKQIFSLIMRPNRRCEVKANLETKGKNYTGN-KDLCVQDSYVIIRNSELVCGS 666
           KP  LWTGKQIFS+I+RP+    V+ANL TKGK Y G  +DLC  DSYV I+NSEL+ GS
Sbjct: 226 KPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGS 285

Query: 667 MDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARMASYYMMNRGFSFGIIDVTPGKKL 726
           MDK TLGSG+K++IFYILLRDWG+  A   M RLAR+A  Y+ NRGFS GI DVTPG+ L
Sbjct: 286 MDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGL 345

Query: 727 IEAKNKLLESGYSKCDGYILEMEKGTLQCQPGCTMEETLEAV 768
           ++AK +LL +GY KCD YI  +  G LQ QPGCT EETLEA+
Sbjct: 346 LKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEAL 387


>AY091461-1|AAM12031.1|  435|Homo sapiens RNA polymerase III subunit
            RPC155-C protein.
          Length = 435

 Score =  472 bits (1164), Expect = e-132
 Identities = 232/372 (62%), Positives = 282/372 (75%), Gaps = 6/372 (1%)

Query: 751  GTLQCQPGCTMEETLEAVMLSELSSIRELAAKACFRELHPTNAPLIMAQSGSKGSNINIS 810
            G LQ QPGCT EETLEA++L ELS IR+ A  AC REL  +N+PL MA  GSKGS INIS
Sbjct: 3    GKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINIS 62

Query: 811  QMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARGFVENSFYTGLTPTEFFFHTMG 870
            QMIACVGQQA++G RVP+GFE+RSLPHFE+HSK+PAA+GFV NSFY+GLTPTEFFFHTM 
Sbjct: 63   QMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMA 122

Query: 871  GREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRNATGEVVQFRYGSDGLDPTYME 930
            GREGLVDTAVKTAETGY+QRRLVKSLEDL  QYD+TVR++TG+++QF YG DGLDP  ME
Sbjct: 123  GREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAME 182

Query: 931  GKDRPVDLARVLADVRAKCQDKNAEPLDGDGIVLAAEETLALDDFKTSTDEFKNELLSFL 990
            GKD P++  RVL +++A     +   L  + ++L  E  +   +F    D F  E+  F+
Sbjct: 183  GKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLCCQDSFLQEIKKFI 242

Query: 991  KATAGRVRALRARYA----GC--GRAALQLERLTLTQLVRFLRVCHHKYQRGVIEPGTAV 1044
            K  + +++  R +Y     G    R   QL+R+T TQ+ +FL  C  KY R  +EPG+AV
Sbjct: 243  KGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRDKYMRAQMEPGSAV 302

Query: 1045 GALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIINASRNISTPIITAELMQPY 1104
            GAL AQSIGEPGTQMTLKTFHFAGVASMNIT GVPR+KEIINAS+ ISTPIITA+L +  
Sbjct: 303  GALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDD 362

Query: 1105 DQEFARRVKGRI 1116
            D ++AR VKGRI
Sbjct: 363  DADYARLVKGRI 374


>AY091459-1|AAM12029.1|  374|Homo sapiens RNA polymerase III subunit
           RPC155-A protein.
          Length = 374

 Score =  468 bits (1153), Expect = e-131
 Identities = 226/377 (59%), Positives = 274/377 (72%), Gaps = 4/377 (1%)

Query: 1   MPKEQYRETYVGRKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRM 60
           M KEQ+RET V +KISH+ F + SP  ++Q AHI+V++KNL+ QD Q  P  +GVLD RM
Sbjct: 1   MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM 60

Query: 61  GTNQKDANCETCGLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPES 120
           GT++KD  CETCG  LA+C+GH+GYI L LP FHVGYFRA+I ILQ ICK C  +ML + 
Sbjct: 61  GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE 120

Query: 121 LKKSYRRKFINPEMSYLLKKNLKAVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVHEK 180
            KK +      P ++YL K+ LK  +  K +  + C  C A NG VKK   G+LKI+HEK
Sbjct: 121 EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKC--GLLKIIHEK 178

Query: 181 YRA-KKPTDPIVKKVLMDFHEAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPL 239
           Y+  KK  DPIV   L  F  A E NKEV  ++     + ++PL VLNLF+RIP ED+PL
Sbjct: 179 YKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQ-ENLNPLVVLNLFKRIPAEDVPL 237

Query: 240 LGMNVKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHL 299
           L MN +  +P DLILTRL VPPLCIRPSVVSD+K+GTNEDDLTMK +EI+ +NDVI +H 
Sbjct: 238 LLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKPTEIIFLNDVIKKHR 297

Query: 300 ASAGKCELIQEDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLS 359
            S  K ++I EDWD+LQL  ALYINSE+SGIPL M PKK  RG VQRLKGKQGRFRGNLS
Sbjct: 298 ISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLS 357

Query: 360 GKRVDFSSRTVISPDPN 376
           GKRVDFS RTVISPDPN
Sbjct: 358 GKRVDFSGRTVISPDPN 374


>BC126303-1|AAI26304.1| 1720|Homo sapiens polymerase (RNA) I
            polypeptide A, 194kDa protein.
          Length = 1720

 Score =  359 bits (882), Expect = 4e-98
 Identities = 248/721 (34%), Positives = 374/721 (51%), Gaps = 73/721 (10%)

Query: 250  EDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAGKCELIQ 309
            +D++L R  +  +     +  ++   T +++    +  ++ I+      L      + + 
Sbjct: 333  KDVVLIRKLLALMAQEQKLPEEVATPTTDEE----KDSLIAIDRSFLSTLPGQSLIDKLY 388

Query: 310  EDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLSGKRVDFSSRT 369
              W  LQ H  +  +SEM  +   M  K PG  + Q L+ K+G FR ++ GKRVD+++R+
Sbjct: 389  NIWIRLQSHVNIVFDSEMDKL---MMDKYPG--IRQILEKKEGLFRKHMMGKRVDYAARS 443

Query: 370  VISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANYV-QQRGL 428
            VI PD  +   E+G+P+  A  LTYP+ V P N+Q LR+ V NGP+VHPGA+ V  + G 
Sbjct: 444  VICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGS 503

Query: 429  KTK-KYLKYGNREKIAQEL----------KCGDVVERHLVDGDVVLFNRQPSLHKLSIMC 477
            +T    +    RE +A++L          +   +V RH+ +GD++L NRQP+LH+ SI  
Sbjct: 504  RTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQA 563

Query: 478  HRAKVQP-QRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVII 536
            HRA++ P ++  R +   C  YNADFDGDEMN H PQ+E  RAEA +L      A T   
Sbjct: 564  HRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVL------ACT--- 614

Query: 537  RVSLEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDAT 596
                       + P++G+ L    QD +  G  +T R  FFT+    +L    L   D  
Sbjct: 615  -------DQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT--DKV 665

Query: 597  MRIDMPPPAIIKPRKLWTGKQIFS-LIMRPNRRCEVKANLETKGK------------NYT 643
             R+ +  P+I+KP  LWTGKQ+ S L++       +  NL  K K            +  
Sbjct: 666  GRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVP 725

Query: 644  GNKDLCVQDSYVIIRNSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARM 703
            G     + +S VIIR  EL+CG +DK+  GS +   + +     +G E + + +  LAR+
Sbjct: 726  GFNPDSMCESQVIIREGELLCGVLDKAHYGS-SAYGLVHCCYEIYGGETSGKVLTCLARL 784

Query: 704  -ASYYMMNRGFSFGIIDVTPGKKLIEAKNKLLE-----------SGYSKCDGYILEMEKG 751
              +Y  + RGF+ G+ D+    K    + +++E           +  +  +    +  +G
Sbjct: 785  FTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRG 844

Query: 752  TLQ-CQPGCTMEE--TLEAVMLSELSSIRELAAKACFR-ELH---PTNAPLIMAQSGSKG 804
              Q    G    +   ++     E++       KAC    LH   P N+  +M QSG+KG
Sbjct: 845  KWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKG 904

Query: 805  SNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARGFVENSFYTGLTPTEF 864
            S +N  Q+   +GQ  L G+R P     +SLP FE +   P A GFV   F TG+ P EF
Sbjct: 905  STVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEF 964

Query: 865  FFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRNATGEVVQFRYGSDGL 924
            FFH M GREGLVDTAVKT+ +GYLQR ++K LE LV+QYD+TVR++ G VVQF YG DGL
Sbjct: 965  FFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGL 1024

Query: 925  D 925
            D
Sbjct: 1025 D 1025



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 1199 KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 1258

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 1259 IKTPMMSVPVLN--TKKALKRVK 1279



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 2/109 (1%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R++  ++F + S   +++ + ++ IT   +L D    P+ +G+ D  +G       C TC
Sbjct: 10  RRLQGISFGMYSAEELKKLS-VKSITNPRYL-DSLGNPSANGLYDLALGPADSKEVCSTC 67

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESL 121
               + C GH G+I+L L V++   F  +  +L+  C  C  +  P ++
Sbjct: 68  VQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAV 116


>BC117173-1|AAI17174.1| 1720|Homo sapiens polymerase (RNA) I
            polypeptide A, 194kDa protein.
          Length = 1720

 Score =  359 bits (882), Expect = 4e-98
 Identities = 248/721 (34%), Positives = 374/721 (51%), Gaps = 73/721 (10%)

Query: 250  EDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAGKCELIQ 309
            +D++L R  +  +     +  ++   T +++    +  ++ I+      L      + + 
Sbjct: 333  KDVVLIRKLLALMAQEQKLPEEVATPTTDEE----KDSLIAIDRSFLSTLPGQSLIDKLY 388

Query: 310  EDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLSGKRVDFSSRT 369
              W  LQ H  +  +SEM  +   M  K PG  + Q L+ K+G FR ++ GKRVD+++R+
Sbjct: 389  NIWIRLQSHVNIVFDSEMDKL---MMDKYPG--IRQILEKKEGLFRKHMMGKRVDYAARS 443

Query: 370  VISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANYV-QQRGL 428
            VI PD  +   E+G+P+  A  LTYP+ V P N+Q LR+ V NGP+VHPGA+ V  + G 
Sbjct: 444  VICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGS 503

Query: 429  KTK-KYLKYGNREKIAQEL----------KCGDVVERHLVDGDVVLFNRQPSLHKLSIMC 477
            +T    +    RE +A++L          +   +V RH+ +GD++L NRQP+LH+ SI  
Sbjct: 504  RTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQA 563

Query: 478  HRAKVQP-QRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVII 536
            HRA++ P ++  R +   C  YNADFDGDEMN H PQ+E  RAEA +L      A T   
Sbjct: 564  HRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVL------ACT--- 614

Query: 537  RVSLEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDAT 596
                       + P++G+ L    QD +  G  +T R  FFT+    +L    L   D  
Sbjct: 615  -------DQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT--DKV 665

Query: 597  MRIDMPPPAIIKPRKLWTGKQIFS-LIMRPNRRCEVKANLETKGK------------NYT 643
             R+ +  P+I+KP  LWTGKQ+ S L++       +  NL  K K            +  
Sbjct: 666  GRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVP 725

Query: 644  GNKDLCVQDSYVIIRNSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARM 703
            G     + +S VIIR  EL+CG +DK+  GS +   + +     +G E + + +  LAR+
Sbjct: 726  GFNPDSMCESQVIIREGELLCGVLDKAHYGS-SAYGLVHCCYEIYGGETSGKVLTCLARL 784

Query: 704  -ASYYMMNRGFSFGIIDVTPGKKLIEAKNKLLE-----------SGYSKCDGYILEMEKG 751
              +Y  + RGF+ G+ D+    K    + +++E           +  +  +    +  +G
Sbjct: 785  FTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRG 844

Query: 752  TLQ-CQPGCTMEE--TLEAVMLSELSSIRELAAKACFR-ELH---PTNAPLIMAQSGSKG 804
              Q    G    +   ++     E++       KAC    LH   P N+  +M QSG+KG
Sbjct: 845  KWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKG 904

Query: 805  SNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARGFVENSFYTGLTPTEF 864
            S +N  Q+   +GQ  L G+R P     +SLP FE +   P A GFV   F TG+ P EF
Sbjct: 905  STVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEF 964

Query: 865  FFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRNATGEVVQFRYGSDGL 924
            FFH M GREGLVDTAVKT+ +GYLQR ++K LE LV+QYD+TVR++ G VVQF YG DGL
Sbjct: 965  FFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGL 1024

Query: 925  D 925
            D
Sbjct: 1025 D 1025



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 1199 KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 1258

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 1259 IKTPMMSVPVLN--TKKALKRVK 1279



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 2/109 (1%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R++  ++F + S   +++ + ++ IT   +L D    P+ +G+ D  +G       C TC
Sbjct: 10  RRLQGISFGMYSAEELKKLS-VKSITNPRYL-DSLGNPSANGLYDLALGPADSKEVCSTC 67

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESL 121
               + C GH G+I+L L V++   F  +  +L+  C  C  +  P ++
Sbjct: 68  VQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAV 116


>BC073968-1|AAH73968.1| 1032|Homo sapiens POLR1A protein protein.
          Length = 1032

 Score =  359 bits (882), Expect = 4e-98
 Identities = 248/721 (34%), Positives = 374/721 (51%), Gaps = 73/721 (10%)

Query: 250  EDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAGKCELIQ 309
            +D++L R  +  +     +  ++   T +++    +  ++ I+      L      + + 
Sbjct: 333  KDVVLIRKLLALMAQEQKLPEEVATPTTDEE----KDSLIAIDRSFLSTLPGQSLIDKLY 388

Query: 310  EDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLSGKRVDFSSRT 369
              W  LQ H  +  +SEM  +   M  K PG  + Q L+ K+G FR ++ GKRVD+++R+
Sbjct: 389  NIWIRLQSHVNIVFDSEMDKL---MMDKYPG--IRQILEKKEGLFRKHMMGKRVDYAARS 443

Query: 370  VISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANYV-QQRGL 428
            VI PD  +   E+G+P+  A  LTYP+ V P N+Q LR+ V NGP+VHPGA+ V  + G 
Sbjct: 444  VICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGS 503

Query: 429  KTK-KYLKYGNREKIAQEL----------KCGDVVERHLVDGDVVLFNRQPSLHKLSIMC 477
            +T    +    RE +A++L          +   +V RH+ +GD++L NRQP+LH+ SI  
Sbjct: 504  RTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQA 563

Query: 478  HRAKVQP-QRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVII 536
            HRA++ P ++  R +   C  YNADFDGDEMN H PQ+E  RAEA +L      A T   
Sbjct: 564  HRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVL------ACT--- 614

Query: 537  RVSLEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDAT 596
                       + P++G+ L    QD +  G  +T R  FFT+    +L    L   D  
Sbjct: 615  -------DQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT--DKV 665

Query: 597  MRIDMPPPAIIKPRKLWTGKQIFS-LIMRPNRRCEVKANLETKGK------------NYT 643
             R+ +  P+I+KP  LWTGKQ+ S L++       +  NL  K K            +  
Sbjct: 666  GRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVP 725

Query: 644  GNKDLCVQDSYVIIRNSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARM 703
            G     + +S VIIR  EL+CG +DK+  GS +   + +     +G E + + +  LAR+
Sbjct: 726  GFNPDSMCESQVIIREGELLCGVLDKAHYGS-SAYGLVHCCYEIYGGETSGKVLTCLARL 784

Query: 704  -ASYYMMNRGFSFGIIDVTPGKKLIEAKNKLLE-----------SGYSKCDGYILEMEKG 751
              +Y  + RGF+ G+ D+    K    + +++E           +  +  +    +  +G
Sbjct: 785  FTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRG 844

Query: 752  TLQ-CQPGCTMEE--TLEAVMLSELSSIRELAAKACFR-ELH---PTNAPLIMAQSGSKG 804
              Q    G    +   ++     E++       KAC    LH   P N+  +M QSG+KG
Sbjct: 845  KWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKG 904

Query: 805  SNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARGFVENSFYTGLTPTEF 864
            S +N  Q+   +GQ  L G+R P     +SLP FE +   P A GFV   F TG+ P EF
Sbjct: 905  STVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEF 964

Query: 865  FFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRNATGEVVQFRYGSDGL 924
            FFH M GREGLVDTAVKT+ +GYLQR ++K LE LV+QYD+TVR++ G VVQF YG DGL
Sbjct: 965  FFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGL 1024

Query: 925  D 925
            D
Sbjct: 1025 D 1025



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 2/109 (1%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R++  ++F + S   +++ + ++ IT   +L D    P+ +G+ D  +G       C TC
Sbjct: 10  RRLQGISFGMYSAEELKKLS-VKSITNPRYL-DSLGNPSANGLYDLALGPADSKEVCSTC 67

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESL 121
               + C GH G+I+L L V++   F  +  +L+  C  C  +  P ++
Sbjct: 68  VQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAV 116


>U33460-1|AAC99959.1| 1717|Homo sapiens DNA-directed RNA polymerase I,
            largest subunit protein.
          Length = 1717

 Score =  355 bits (873), Expect = 5e-97
 Identities = 247/721 (34%), Positives = 372/721 (51%), Gaps = 73/721 (10%)

Query: 250  EDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAGKCELIQ 309
            +D++L R  +  +     +  ++   T +++    +  ++ I+      L      + + 
Sbjct: 333  KDVVLIRKLLALMAQEQKLPEEVATPTTDEE----KDSLIAIDRSFLSTLPGQSLIDKLY 388

Query: 310  EDWDYLQLHAALYINSEMSGIPLAMQPKKPGRGLVQRLKGKQGRFRGNLSGKRVDFSSRT 369
              W  LQ H  +  +SEM  +   M+ K PG  + Q L+ K+G FR ++ GKRVD ++R+
Sbjct: 389  NIWIRLQSHVNIVFDSEMDKL---MRDKYPG--IRQILEKKEGLFRKHMMGKRVDSTARS 443

Query: 370  VISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANYV-QQRGL 428
            VI PD  +   E+G+P+  A  LTYP+ V P N+Q LR+ V NGP+VHPGA+ V  + G 
Sbjct: 444  VICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGS 503

Query: 429  KTK-KYLKYGNREKIAQEL----------KCGDVVERHLVDGDVVLFNRQPSLHKLSIMC 477
            +T    +    RE +A++L          +   +V RH+ +GD++L NRQP+LH+ SI  
Sbjct: 504  RTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQA 563

Query: 478  HRAKVQP-QRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVII 536
            HRA++ P ++  R +   C  YNADFDGDEMN H PQ+E  RAEA +L      A T   
Sbjct: 564  HRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVL------ACT--- 614

Query: 537  RVSLEQNKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTKSEAQQLAACLLAGPDAT 596
                       + P++G+ L    QD +  G  +T R  FFT+    +L    L   D  
Sbjct: 615  -------DQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT--DKV 665

Query: 597  MRIDMPPPAIIKPRKLWTGKQIFS-LIMRPNRRCEVKANLETKGK------------NYT 643
             R+ +  P+I+KP  LWTGKQ+ S L++       +  NL  K K            +  
Sbjct: 666  GRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVP 725

Query: 644  GNKDLCVQDSYVIIRNSELVCGSMDKSTLGSGTKSSIFYILLRDWGEEYAVRGMWRLARM 703
            G     + +S VIIR  EL+CG +DK+  GS +   + +     +G E + + +  LAR+
Sbjct: 726  GFNPDSMCESQVIIREGELLCGVLDKAHYGS-SAYGLVHCCYEIYGGETSGKVLTCLARL 784

Query: 704  -ASYYMMNRGFSFGIIDVTPGKKLIEAKNKLLE-----------SGYSKCDGYILEMEKG 751
              +Y  + RGF+ G+ D+    K    + +++E           +  +  +    +  +G
Sbjct: 785  FTAYLQLYRGFTLGVEDILVKPKRDVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRG 844

Query: 752  TLQ-CQPGCTMEE--TLEAVMLSELSSIRELAAKACFR-ELH---PTNAPLIMAQSGSKG 804
              Q    G    +   ++     E++       KAC    LH   P N   +M QSG+KG
Sbjct: 845  KWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENTLQLMVQSGAKG 904

Query: 805  SNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARGFVENSFYTGLTPTEF 864
            S +N  Q+   +GQ  L G+  P     +SLP FE +   P A GFV   F TG+ P EF
Sbjct: 905  STVNTMQISCLLGQIELEGRSTPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEF 964

Query: 865  FFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRNATGEVVQFRYGSDGL 924
            FFH M GREGLVDTAVKT+ +GYLQR ++K LE LV+QYD+TVR++ G VVQF YG DGL
Sbjct: 965  FFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGL 1024

Query: 925  D 925
            D
Sbjct: 1025 D 1025



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 1200 KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 1259

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 1260 IKTPMMSVPVLN--TKKALKRVK 1280



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 2/109 (1%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R++  ++F + S   +++ + ++ IT   +L D    P+ +G+ D  +G       C TC
Sbjct: 10  RRLQGISFGMYSAEELKKLS-VKSITNPRYL-DSLGNPSANGLYDLALGPADSKEVCSTC 67

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESL 121
               + C GH G+I+L L V++   F  +  +L+  C  C  +  P ++
Sbjct: 68  VQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAV 116


>BC067295-1|AAH67295.1|  566|Homo sapiens POLR2A protein protein.
          Length = 566

 Score =  343 bits (843), Expect = 2e-93
 Identities = 214/577 (37%), Positives = 321/577 (55%), Gaps = 45/577 (7%)

Query: 13  RKISHVTFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETC 72
           R I  V F V SP  +++ +  E   K     +G R P   G++D R G  ++   C+TC
Sbjct: 16  RTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGR-PKLGGLMDPRQGVIERTGRCQTC 74

Query: 73  GLGLAECVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINP 132
              + EC GHFG+I+L  PVFHVG+    + +L+ +C  C+K+++  +          NP
Sbjct: 75  AGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSN----------NP 124

Query: 133 EMSYLLKKNLKAVVHKKAKTFSKCPS---CEAINGMVKKSSI----GILKIVHEK-YRAK 184
           ++  +L K+      +    +  C     CE    M  K  +    G   +  EK +   
Sbjct: 125 KIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGC 184

Query: 185 KPTDPIVKKVLMDFH-EAKESNKEVAAMINSGLVKEMSPLEVLNLFRRIPDEDIPLLGMN 243
               P +++  ++ + E K  N++        ++  +SP  V  +F+RI DE+  +LGM 
Sbjct: 185 GRYQPRIRRSGLELYAEWKHVNEDSQ---EKKIL--LSPERVHEIFKRISDEECFVLGME 239

Query: 244 VKLSRPEDLILTRLPVPPLCIRPSVVSDIKAGTNEDDLTMKQSEILLINDVIARHLASAG 303
            + +RPE +I+T LPVPPL +RP+VV    A  N+DDLT K ++I+ IN+ + R+  +  
Sbjct: 240 PRYARPEWMIVTVLPVPPLSVRPAVVMQGSA-RNQDDLTHKLADIVKINNQLRRNEQNGA 298

Query: 304 KCELIQEDWDYLQLHAALYINSEMSGIPLAMQPK-KPGRGLVQRLKGKQGRFRGNLSGKR 362
              +I ED   LQ H A  +++E+ G+P AMQ   +P + L QRLKGK+GR RGNL GKR
Sbjct: 299 AAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKR 358

Query: 363 VDFSSRTVISPDPNLQIQEVGVPVHVAKILTYPERVFPANLQWLRRLVCNGPDVHPGANY 422
           VDFS+RTVI+PDPNL I +VGVP  +A  +T+ E V P N+  L+ LV  G   +PGA Y
Sbjct: 359 VDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKY 418

Query: 423 VQQRGLKTKKYLKYGNREKIAQELKCGDVVERHLVDGDVVLFNRQPSLHKLSIMCHRAKV 482
           +  R    +  L++  +      L+ G  VERH+ DGD+V+FNRQP+LHK+S+M HR ++
Sbjct: 419 II-RDNGDRIDLRFHPKPSDLH-LQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRI 476

Query: 483 QPQRTFRFNECVCTPYNADFDGDEMNMHLPQTEEARAEALILMGSHNTAVTVIIRVSLEQ 542
            P  TFR N  V TPYNADFDGDEMN+HLPQ+ E RAE           + ++ R+    
Sbjct: 477 LPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEI--------QELAMVPRM---- 524

Query: 543 NKSNLVTPRNGELLIAATQDFITGGYLITQRDTFFTK 579
               +VTP++   ++   QD +T     T+RD F  +
Sbjct: 525 ----IVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLER 557


>AC012511-1|AAY24277.1|  922|Homo sapiens unknown protein.
          Length = 922

 Score =  157 bits (381), Expect = 2e-37
 Identities = 76/136 (55%), Positives = 94/136 (69%)

Query: 790 PTNAPLIMAQSGSKGSNINISQMIACVGQQALNGKRVPNGFEDRSLPHFERHSKIPAARG 849
           P N+  +M QSG+KGS +N  Q+   +GQ  L G+R P     +SLP FE +   P A G
Sbjct: 92  PENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGG 151

Query: 850 FVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLVKSLEDLVLQYDMTVRN 909
           FV   F TG+ P EFFFH M GREGLVDTAVKT+ +GYLQR ++K LE LV+QYD+TVR+
Sbjct: 152 FVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRD 211

Query: 910 ATGEVVQFRYGSDGLD 925
           + G VVQF YG DGLD
Sbjct: 212 SDGSVVQFLYGEDGLD 227



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 401  KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 460

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 461  IKTPMMSVPVLN--TKKALKRVK 481


>U33823-1|AAD09356.1|  441|Homo sapiens DNA-directed RNA polymerase
           I largest subunit protein.
          Length = 441

 Score =  123 bits (297), Expect = 3e-27
 Identities = 58/92 (63%), Positives = 68/92 (73%)

Query: 834 SLPHFERHSKIPAARGFVENSFYTGLTPTEFFFHTMGGREGLVDTAVKTAETGYLQRRLV 893
           SLP FE +   P A GFV   F TG+ P EFFFH M GREGLVDTAVKT+ + YLQR ++
Sbjct: 1   SLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSAYLQRCII 60

Query: 894 KSLEDLVLQYDMTVRNATGEVVQFRYGSDGLD 925
           K LE LV+QYD+TVR++ G VVQF YG DGLD
Sbjct: 61  KHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLD 92



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 267  KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 326

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 327  IKTPMMSVPVLN--TKKALKRVK 347


>BC017115-1|AAH17115.2|  574|Homo sapiens POLR1A protein protein.
          Length = 574

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 46/83 (55%), Positives = 61/83 (73%), Gaps = 3/83 (3%)

Query: 1032 KYQRGVIEPGTAVGALAAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRVKEIIN-ASRN 1090
            K+QR + EPG AVG LAAQSIGEP TQMTL TFHFAG   MN+T G+PR++EI+  AS N
Sbjct: 53   KWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASAN 112

Query: 1091 ISTPIITAELMQPYDQEFARRVK 1113
            I TP+++  ++    ++  +RVK
Sbjct: 113  IKTPMMSVPVLN--TKKALKRVK 133


>AY091462-1|AAM12032.1|  299|Homo sapiens RNA polymerase III subunit
            RPC155-D protein.
          Length = 299

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/77 (48%), Positives = 46/77 (59%), Gaps = 3/77 (3%)

Query: 1109 ARRVKGRICTSKLKVKPAEVTAVSAWAIKVTG-EPSKSCGWLNMSLQQLGRQLPAVVVKG 1167
            A  V+  ICTSKL+VKP +V       + VT  E SKS   +   LQ L   LP VVV+G
Sbjct: 55   AETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSS--MYYVLQFLKEDLPKVVVQG 112

Query: 1168 LPQVSRAVIACDDSSEK 1184
            +P+VSRAVI  D+ S K
Sbjct: 113  IPEVSRAVIHIDEQSGK 129


>M21610-1|AAA60135.1|  113|Homo sapiens POLR2 protein.
          Length = 113

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 25/50 (50%), Positives = 37/50 (74%)

Query: 220 MSPLEVLNLFRRIPDEDIPLLGMNVKLSRPEDLILTRLPVPPLCIRPSVV 269
           +SP  V  +F+RI DE+  +LG+  + +RPE +I+T LPVPPL +RP+VV
Sbjct: 26  LSPERVHEIFKRISDEECFVLGIEPRYARPESMIVTVLPVPPLSVRPAVV 75


>AK025568-1|BAB15171.1|  495|Homo sapiens protein ( Homo sapiens cDNA:
            FLJ21915 fis, clone HEP03920. ).
          Length = 495

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/56 (46%), Positives = 39/56 (69%), Gaps = 3/56 (5%)

Query: 1059 MTLKTFHFAGVASMNITQGVPRVKEIIN-ASRNISTPIITAELMQPYDQEFARRVK 1113
            MTL TFHFAG   MN+T G+PR++EI+  AS NI TP+++  ++    ++  +RVK
Sbjct: 1    MTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLN--TKKALKRVK 54


>BC014399-1|AAH14399.1|  162|Homo sapiens POLR3A protein protein.
          Length = 162

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 19/32 (59%), Positives = 23/32 (71%)

Query: 1153 LQQLGRQLPAVVVKGLPQVSRAVIACDDSSEK 1184
            LQ L   LP VVV+G+P+VSRAVI  D+ S K
Sbjct: 5    LQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGK 36


>AF187991-1|AAF04107.1|  706|Homo sapiens zinc finger protein ZNF225
           protein.
          Length = 706

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 25/170 (14%)

Query: 19  TFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETCGLGLAE 78
           +F   S   I Q  H+     N  +   +   + H  + +R+ T +K   CE CG G + 
Sbjct: 184 SFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHQQIHQRIHTGEKPFKCEQCGKGFSR 243

Query: 79  CVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINPE----- 133
             G + + +L     H G       +   IC++C K  + +S  + ++R     +     
Sbjct: 244 RSGLYVHRKL-----HTG-------VKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCD 291

Query: 134 ---MSYLLKKNLK--AVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVH 178
               S+  + NL   ++VH + K F +C +C    G+  KS++   ++VH
Sbjct: 292 ICCKSFRSRANLNRHSMVHMREKPF-RCDTCGKSFGL--KSALNSHRMVH 338


>BC108912-1|AAI08913.1|  706|Homo sapiens zinc finger protein 225
           protein.
          Length = 706

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 25/170 (14%)

Query: 19  TFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETCGLGLAE 78
           +F   S   I Q  H+     N  +   +   + H  + +R+ T +K   CE CG G + 
Sbjct: 184 SFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEKPFKCEQCGKGFSR 243

Query: 79  CVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINPE----- 133
             G + + +L     H G       +   IC++C K  + +S  + ++R     +     
Sbjct: 244 RSGLYVHRKL-----HTG-------VKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCD 291

Query: 134 ---MSYLLKKNLK--AVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVH 178
               S+  + NL   ++VH + K F +C +C    G+  KS++   ++VH
Sbjct: 292 ICCKSFRSRANLNRHSMVHMREKPF-RCDTCGKSFGL--KSALNSHRMVH 338


>AK223477-1|BAD97197.1|  706|Homo sapiens zinc finger protein 225
           variant protein.
          Length = 706

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 25/170 (14%)

Query: 19  TFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETCGLGLAE 78
           +F   S   I Q  H+     N  +   +   + H  + +R+ T +K   CE CG G + 
Sbjct: 184 SFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEKPFKCEQCGKGFSR 243

Query: 79  CVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINPE----- 133
             G + + +L     H G       +   IC++C K  + +S  + ++R     +     
Sbjct: 244 RSGLYVHRKL-----HTG-------VKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCD 291

Query: 134 ---MSYLLKKNLK--AVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVH 178
               S+  + NL   ++VH + K F +C +C    G+  KS++   ++VH
Sbjct: 292 ICCKSFRSRANLNRHSMVHMREKPF-RCDTCGKSFGL--KSALNSHRMVH 338


>AC074331-1|AAF88105.1|  628|Homo sapiens ZNF225 [amino acids
           79-706] protein.
          Length = 628

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 25/170 (14%)

Query: 19  TFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETCGLGLAE 78
           +F   S   I Q  H+     N  +   +   + H  + +R+ T +K   CE CG G + 
Sbjct: 106 SFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEKPFKCEQCGKGFSR 165

Query: 79  CVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINPE----- 133
             G + + +L     H G       +   IC++C K  + +S  + ++R     +     
Sbjct: 166 RSGLYVHRKL-----HTG-------VKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCD 213

Query: 134 ---MSYLLKKNLK--AVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVH 178
               S+  + NL   ++VH + K F +C +C    G+  KS++   ++VH
Sbjct: 214 ICCKSFRSRANLNRHSMVHMREKPF-RCDTCGKSFGL--KSALNSHRMVH 260


>AC021092-2|AAF24967.1|  706|Homo sapiens ZNF225 protein.
          Length = 706

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 25/170 (14%)

Query: 19  TFNVDSPSLIQQSAHIEVITKNLFLQDGQRVPAPHGVLDRRMGTNQKDANCETCGLGLAE 78
           +F   S   I Q  H+     N  +   +   + H  + +R+ T +K   CE CG G + 
Sbjct: 184 SFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEKPFKCEQCGKGFSR 243

Query: 79  CVGHFGYIQLTLPVFHVGYFRAIITILQTICKECAKVMLPESLKKSYRRKFINPE----- 133
             G + + +L     H G       +   IC++C K  + +S  + ++R     +     
Sbjct: 244 RSGLYVHRKL-----HTG-------VKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCD 291

Query: 134 ---MSYLLKKNLK--AVVHKKAKTFSKCPSCEAINGMVKKSSIGILKIVH 178
               S+  + NL   ++VH + K F +C +C    G+  KS++   ++VH
Sbjct: 292 ICCKSFRSRANLNRHSMVHMREKPF-RCDTCGKSFGL--KSALNSHRMVH 338


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.135    0.398 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 172,185,837
Number of Sequences: 224733
Number of extensions: 7353838
Number of successful extensions: 15575
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 15431
Number of HSP's gapped (non-prelim): 99
length of query: 1191
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1093
effective length of database: 51,211,004
effective search space: 55973627372
effective search space used: 55973627372
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)

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