BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000742-TA|BGIBMGA000742-PA|IPR003877|SPla/RYanodine receptor SPRY, IPR001870|B302, (SPRY)-like (546 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC013173-1|AAH13173.1| 576|Homo sapiens ring finger and SPRY do... 500 e-141 AK172845-1|BAD18809.1| 576|Homo sapiens protein ( Homo sapiens ... 500 e-141 AB075852-1|BAB85558.1| 576|Homo sapiens KIAA1972 protein protein. 500 e-141 BC130632-1|AAI30633.1| 1314|Homo sapiens ring finger protein 123... 78 7e-14 AY744152-1|AAU93470.1| 1314|Homo sapiens ubiquitin ligase protein. 78 7e-14 U48508-1|AAC51191.1| 5038|Homo sapiens skeletal muscle ryanodine... 69 6e-11 J05200-1|AAA60294.1| 5032|Homo sapiens RYR1 protein. 69 6e-11 AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3 pr... 66 4e-10 AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine recepto... 66 4e-10 AL834402-1|CAD39064.1| 85|Homo sapiens hypothetical protein pr... 65 5e-10 X98330-1|CAA66975.1| 4967|Homo sapiens ryanodine receptor 2 prot... 64 1e-09 AL513130-1|CAI15936.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL445473-1|CAH71393.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL442065-1|CAI15350.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL391809-1|CAI14440.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL365332-1|CAH71369.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL359924-1|CAI22065.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AL356773-1|CAH73918.1| 4965|Homo sapiens ryanodine receptor 2 (c... 64 1e-09 AJ300340-1|CAC18855.1| 4967|Homo sapiens ryanodine receptor 2 pr... 64 1e-09 X70649-1|CAA49992.1| 740|Homo sapiens member of DEAD box protei... 50 3e-05 EF418571-1|ABN70941.1| 740|Homo sapiens DEAD box polypeptide 1 ... 50 3e-05 EF418570-1|ABN70940.1| 740|Homo sapiens DEAD box polypeptide 1 ... 50 3e-05 BC053673-1|AAH53673.1| 740|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 50 3e-05 BC012132-1|AAH12132.1| 740|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 50 3e-05 Z93020-1|CAI21594.1| 729|Homo sapiens RAN binding protein 9 pro... 36 0.48 BC052781-1|AAH52781.1| 802|Homo sapiens RANBP9 protein protein. 36 0.48 AL441883-5|CAI19841.1| 729|Homo sapiens RAN binding protein 9 p... 36 0.48 AF064606-1|AAC17111.1| 243|Homo sapiens KB07 protein protein. 36 0.48 AB055311-1|BAB62525.1| 729|Homo sapiens RanBPM protein. 36 0.48 BC015936-1|AAH15936.1| 534|Homo sapiens ASH2L protein protein. 34 1.1 AF056718-1|AAC13564.1| 628|Homo sapiens ash2l1 protein. 34 1.1 AF056717-1|AAC13563.1| 501|Homo sapiens ash2l2 protein. 34 1.1 AB022785-1|BAA74520.1| 628|Homo sapiens ASH2L protein. 34 1.1 AB020982-1|BAA35127.1| 628|Homo sapiens ASH2L protein. 34 1.1 BC019886-1|AAH19886.1| 486|Homo sapiens Unknown (protein for IM... 34 1.5 BC121177-1|AAI21178.1| 620|Homo sapiens RAN binding protein 10 ... 33 2.6 BC121176-1|AAI21177.1| 620|Homo sapiens RAN binding protein 10 ... 33 2.6 BC099917-1|AAH99917.1| 620|Homo sapiens RAN binding protein 10 ... 33 2.6 AY337313-1|AAR01220.1| 620|Homo sapiens Ran-binding protein 10 ... 33 2.6 AB040897-1|BAA95988.1| 621|Homo sapiens KIAA1464 protein protein. 33 2.6 M91455-1|AAA60295.1| 125|Homo sapiens ryanodine receptor protein. 32 6.0 BC104804-1|AAI04805.1| 950|Homo sapiens protocadherin alpha 9 p... 31 7.9 BC104802-1|AAI04803.1| 950|Homo sapiens protocadherin alpha 9 p... 31 7.9 AJ007610-1|CAC22257.1| 950|Homo sapiens protocadherin alpha 9 p... 31 7.9 AF152487-1|AAD43748.1| 842|Homo sapiens protocadherin alpha 9 s... 31 7.9 AF152317-1|AAD43711.1| 950|Homo sapiens protocadherin alpha 9 p... 31 7.9 AC005609-5|AAC34313.1| 842|Homo sapiens KIAA0345-like 5 protein. 31 7.9 AB002343-1|BAA20803.2| 845|Homo sapiens KIAA0345 protein. 31 7.9 >BC013173-1|AAH13173.1| 576|Homo sapiens ring finger and SPRY domain containing 1 protein. Length = 576 Score = 500 bits (1232), Expect = e-141 Identities = 242/455 (53%), Positives = 318/455 (69%), Gaps = 8/455 (1%) Query: 47 VDQLVMEMLTLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLDNPLGPSA 106 VD LV++ L +I + VDND+E P ++ LH +A+ +EGWL VV S++ VIPL++PLGP+ Sbjct: 100 VDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAV 159 Query: 107 ITIVFDDCPLPSRDSVIKLTKLFRLSRQRALSNALDVKMKRNMCVVLGCIAEKLAGPNSV 166 IT++ D+CPLP++D++ KLT++ L+ + A ++ RN VLGC+AEKLAGP S+ Sbjct: 160 ITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASI 219 Query: 167 AVLTEETLDFLLAFLDTNFEPCIVLFALIALEKFAHTTENKLVIRSRFDKEDVNPLLKLE 226 +L+ L++LL L P ++LFALIALEKFA T+ENKL I + + L+ LE Sbjct: 220 GLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTIS---ESSISDRLVTLE 276 Query: 227 KLANNEDYVWRQVGFCAQWALDNLFVIENRPLSYETVDMTPINVILNSHDVSEYLKISCN 286 AN+ DY+ RQVGFCAQW+LDNLF+ E R L+YE V+++ I +LNS+DVSEYLKIS + Sbjct: 277 SWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPH 336 Query: 287 GLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDL 346 GLEARCD+ SFESVRCTF VD G WYYEVT+VT GVMQIGWAT++S FLNHEGYGIGDD Sbjct: 337 GLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDE 396 Query: 347 YSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIF 406 YS +YDGCR+LIWY A+ + P W+ GD +G L+DLN ++ IF LNG L P ++F Sbjct: 397 YSCAYDGCRQLIWYNAR-SKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVF 455 Query: 407 ETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTDRPFMAFNDYARLTDEEKKVLPRR 466 +T G QQC FNFG PF +PP+ + F FNDYA LT EEK +LPR Sbjct: 456 SST---VSGFFAAASFMSYQQCEFNFGAKPFKYPPSMK-FSTFNDYAFLTAEEKIILPRH 511 Query: 467 YYLEKVRNASIPENACTLCYDAVADCTLEPCFHND 501 L ++ SI EN C+LC D VAD L+PC H+D Sbjct: 512 RRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSD 546 >AK172845-1|BAD18809.1| 576|Homo sapiens protein ( Homo sapiens cDNA FLJ24006 fis, clone KAT02158. ). Length = 576 Score = 500 bits (1232), Expect = e-141 Identities = 242/455 (53%), Positives = 318/455 (69%), Gaps = 8/455 (1%) Query: 47 VDQLVMEMLTLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLDNPLGPSA 106 VD LV++ L +I + VDND+E P ++ LH +A+ +EGWL VV S++ VIPL++PLGP+ Sbjct: 100 VDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAV 159 Query: 107 ITIVFDDCPLPSRDSVIKLTKLFRLSRQRALSNALDVKMKRNMCVVLGCIAEKLAGPNSV 166 IT++ D+CPLP++D++ KLT++ L+ + A ++ RN VLGC+AEKLAGP S+ Sbjct: 160 ITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASI 219 Query: 167 AVLTEETLDFLLAFLDTNFEPCIVLFALIALEKFAHTTENKLVIRSRFDKEDVNPLLKLE 226 +L+ L++LL L P ++LFALIALEKFA T+ENKL I + + L+ LE Sbjct: 220 GLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTIS---ESSISDRLVTLE 276 Query: 227 KLANNEDYVWRQVGFCAQWALDNLFVIENRPLSYETVDMTPINVILNSHDVSEYLKISCN 286 AN+ DY+ RQVGFCAQW+LDNLF+ E R L+YE V+++ I +LNS+DVSEYLKIS + Sbjct: 277 SWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPH 336 Query: 287 GLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDL 346 GLEARCD+ SFESVRCTF VD G WYYEVT+VT GVMQIGWAT++S FLNHEGYGIGDD Sbjct: 337 GLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDE 396 Query: 347 YSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIF 406 YS +YDGCR+LIWY A+ + P W+ GD +G L+DLN ++ IF LNG L P ++F Sbjct: 397 YSCAYDGCRQLIWYNAR-SKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVF 455 Query: 407 ETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTDRPFMAFNDYARLTDEEKKVLPRR 466 +T G QQC FNFG PF +PP+ + F FNDYA LT EEK +LPR Sbjct: 456 SST---VSGFFAAASFMSYQQCEFNFGAKPFKYPPSMK-FSTFNDYAFLTAEEKIILPRH 511 Query: 467 YYLEKVRNASIPENACTLCYDAVADCTLEPCFHND 501 L ++ SI EN C+LC D VAD L+PC H+D Sbjct: 512 RRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSD 546 >AB075852-1|BAB85558.1| 576|Homo sapiens KIAA1972 protein protein. Length = 576 Score = 500 bits (1232), Expect = e-141 Identities = 242/455 (53%), Positives = 318/455 (69%), Gaps = 8/455 (1%) Query: 47 VDQLVMEMLTLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLDNPLGPSA 106 VD LV++ L +I + VDND+E P ++ LH +A+ +EGWL VV S++ VIPL++PLGP+ Sbjct: 100 VDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAV 159 Query: 107 ITIVFDDCPLPSRDSVIKLTKLFRLSRQRALSNALDVKMKRNMCVVLGCIAEKLAGPNSV 166 IT++ D+CPLP++D++ KLT++ L+ + A ++ RN VLGC+AEKLAGP S+ Sbjct: 160 ITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASI 219 Query: 167 AVLTEETLDFLLAFLDTNFEPCIVLFALIALEKFAHTTENKLVIRSRFDKEDVNPLLKLE 226 +L+ L++LL L P ++LFALIALEKFA T+ENKL I + + L+ LE Sbjct: 220 GLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTIS---ESSISDRLVTLE 276 Query: 227 KLANNEDYVWRQVGFCAQWALDNLFVIENRPLSYETVDMTPINVILNSHDVSEYLKISCN 286 AN+ DY+ RQVGFCAQW+LDNLF+ E R L+YE V+++ I +LNS+DVSEYLKIS + Sbjct: 277 SWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPH 336 Query: 287 GLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDL 346 GLEARCD+ SFESVRCTF VD G WYYEVT+VT GVMQIGWAT++S FLNHEGYGIGDD Sbjct: 337 GLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDE 396 Query: 347 YSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIF 406 YS +YDGCR+LIWY A+ + P W+ GD +G L+DLN ++ IF LNG L P ++F Sbjct: 397 YSCAYDGCRQLIWYNAR-SKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVF 455 Query: 407 ETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTDRPFMAFNDYARLTDEEKKVLPRR 466 +T G QQC FNFG PF +PP+ + F FNDYA LT EEK +LPR Sbjct: 456 SST---VSGFFAAASFMSYQQCEFNFGAKPFKYPPSMK-FSTFNDYAFLTAEEKIILPRH 511 Query: 467 YYLEKVRNASIPENACTLCYDAVADCTLEPCFHND 501 L ++ SI EN C+LC D VAD L+PC H+D Sbjct: 512 RRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSD 546 >BC130632-1|AAI30633.1| 1314|Homo sapiens ring finger protein 123 protein. Length = 1314 Score = 78.2 bits (184), Expect = 7e-14 Identities = 62/197 (31%), Positives = 84/197 (42%), Gaps = 10/197 (5%) Query: 247 LDNLFVIENRPL-SYETVD--MTPINVILNSHDVSEYLKISCNGLEARCDSYSFESVRCT 303 LD L ++N S V+ + P V+L+ E L + + L +F ++R T Sbjct: 68 LDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRST 127 Query: 304 FQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAK 363 V G W YEV I + G+MQIGW T + F E G+GD S +YDG R W Sbjct: 128 TCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEE--GVGDTHNSYAYDGNRVRKW---N 182 Query: 364 PASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXX 423 + W GDI+ CLIDL+ F LNG L E +R Sbjct: 183 VTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFE--NLSRGLGMAYFPAISLS 240 Query: 424 XXQQCRFNFGHLPFSFP 440 + FNFG P +P Sbjct: 241 FKESVAFNFGSRPLRYP 257 >AY744152-1|AAU93470.1| 1314|Homo sapiens ubiquitin ligase protein. Length = 1314 Score = 78.2 bits (184), Expect = 7e-14 Identities = 62/197 (31%), Positives = 84/197 (42%), Gaps = 10/197 (5%) Query: 247 LDNLFVIENRPL-SYETVD--MTPINVILNSHDVSEYLKISCNGLEARCDSYSFESVRCT 303 LD L ++N S V+ + P V+L+ E L + + L +F ++R T Sbjct: 68 LDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRST 127 Query: 304 FQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAK 363 V G W YEV I + G+MQIGW T + F E G+GD S +YDG R W Sbjct: 128 TCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEE--GVGDTHNSYAYDGNRVRKW---N 182 Query: 364 PASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXX 423 + W GDI+ CLIDL+ F LNG L E +R Sbjct: 183 VTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFE--NLSRGLGMAYFPAISLS 240 Query: 424 XXQQCRFNFGHLPFSFP 440 + FNFG P +P Sbjct: 241 FKESVAFNFGSRPLRYP 257 >U48508-1|AAC51191.1| 5038|Homo sapiens skeletal muscle ryanodine receptor protein. Length = 5038 Score = 68.5 bits (160), Expect = 6e-11 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Query: 289 EARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYS 348 ++RCD ++ V +G WY+E VT G M++GWA +G D + Sbjct: 1065 QSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELR----PDVELGADELA 1120 Query: 349 LSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 ++G R W+ + WQPGD++GC+IDL IF+LNG L Sbjct: 1121 YVFNGHRGQRWHLGSEPFGRP---WQPGDVVGCMIDLTENTIIFTLNGEVL 1168 Score = 50.4 bits (115), Expect = 2e-05 Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFLNH---EGYG---IGDDLYSLSYDGCRK 356 WY+EV + VTP + +++GWA + EG+G +GDDLYS +DG Sbjct: 661 WYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHL 720 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFET 408 + A+P + P D++ C +DL+ F +NG C P +FE+ Sbjct: 721 WTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRING-C--PVQGVFES 769 >J05200-1|AAA60294.1| 5032|Homo sapiens RYR1 protein. Length = 5032 Score = 68.5 bits (160), Expect = 6e-11 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Query: 289 EARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYS 348 ++RCD ++ V +G WY+E VT G M++GWA +G D + Sbjct: 1065 QSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELR----PDVELGADELA 1120 Query: 349 LSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 ++G R W+ + WQPGD++GC+IDL IF+LNG L Sbjct: 1121 YVFNGHRGQRWHLGSEPFGRP---WQPGDVVGCMIDLTENTIIFTLNGEVL 1168 Score = 50.4 bits (115), Expect = 2e-05 Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFLNH---EGYG---IGDDLYSLSYDGCRK 356 WY+EV + VTP + +++GWA + EG+G +GDDLYS +DG Sbjct: 661 WYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHL 720 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFET 408 + A+P + P D++ C +DL+ F +NG C P +FE+ Sbjct: 721 WTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRING-C--PVQGVFES 769 >AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3 protein. Length = 4870 Score = 65.7 bits (153), Expect = 4e-10 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 7/107 (6%) Query: 293 DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYSLSYD 352 D F V ++ V +G WY+E +VT G M++GWA +G D + ++ Sbjct: 1069 DKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCR----PDVELGADDQAFVFE 1124 Query: 353 GCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 G R W++ + WQPGD++GC+I+L+ IF+LNG L Sbjct: 1125 GNRGQRWHQGSGYFGRT---WQPGDVVGCMINLDDASMIFTLNGELL 1168 Score = 46.4 bits (105), Expect = 3e-04 Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 18/114 (15%) Query: 311 WYYEVTI--------VTPGVMQIGWATKNSHFL---NHEGYG---IGDDLYSLSYDGCRK 356 WY+E+ I P +++GWA+ + + EG+G +GDDLYS +DG Sbjct: 660 WYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPCPGGGEGWGGNGVGDDLYSYGFDGLH- 718 Query: 357 LIWYKAKPASVQDLPE--WQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFET 408 +W P +V + + + D++ C +DL F +NG+ + E F T Sbjct: 719 -LWSGRIPRAVASVNQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNT 771 >AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine receptor protein. Length = 4866 Score = 65.7 bits (153), Expect = 4e-10 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 7/107 (6%) Query: 293 DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYSLSYD 352 D F V ++ V +G WY+E +VT G M++GWA +G D + ++ Sbjct: 1070 DKIRFFRVERSYPVRSGKWYFEFEVVTGGDMRVGWARPGCR----PDVELGADDQAFVFE 1125 Query: 353 GCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 G R W++ + WQPGD++GC+I+L+ IF+LNG L Sbjct: 1126 GNRGQRWHQGSGYFGRT---WQPGDVVGCMINLDDASMIFTLNGELL 1169 Score = 33.1 bits (72), Expect = 2.6 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 16/74 (21%) Query: 311 WYYEVTI--------VTPGVMQIGWATKNSHFL---NHEGYG---IGDDLYSLSYDGCRK 356 WY+E+ I P +++GWA+ + + EG+G +GDDLYS +DG Sbjct: 660 WYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLH- 718 Query: 357 LIWYKAKPASVQDL 370 +W P +V + Sbjct: 719 -LWSGRIPRAVASI 731 >AL834402-1|CAD39064.1| 85|Homo sapiens hypothetical protein protein. Length = 85 Score = 65.3 bits (152), Expect = 5e-10 Identities = 30/53 (56%), Positives = 36/53 (67%) Query: 449 FNDYARLTDEEKKVLPRRYYLEKVRNASIPENACTLCYDAVADCTLEPCFHND 501 FNDYA LT EEK +LPR L ++ SI EN C+LC D VAD L+PC H+D Sbjct: 3 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSD 55 >X98330-1|CAA66975.1| 4967|Homo sapiens ryanodine receptor 2 protein. Length = 4967 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1078 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1130 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1131 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1182 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 673 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 732 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 733 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 773 >AL513130-1|CAI15936.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL445473-1|CAH71393.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL442065-1|CAI15350.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL391809-1|CAI14440.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL365332-1|CAH71369.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL359924-1|CAI22065.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AL356773-1|CAH73918.1| 4965|Homo sapiens ryanodine receptor 2 (cardiac) protein. Length = 4965 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1076 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1128 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1129 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1180 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 671 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 730 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 731 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 771 >AJ300340-1|CAC18855.1| 4967|Homo sapiens ryanodine receptor 2 protein. Length = 4967 Score = 64.1 bits (149), Expect = 1e-09 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 285 CNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGD 344 C+G R + E T+ V G WY+E VT G M++GW+ +G Sbjct: 1078 CSGTGERFRIFRAEK---TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQ----PDQELGS 1130 Query: 345 DLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 D + ++DG + W++ + WQ GD++GC++D+N +F+LNG L Sbjct: 1131 DERAFAFDGFKAQRWHQGNEHYGRS---WQAGDVVGCMVDMNEHTMMFTLNGEIL 1182 Score = 40.7 bits (91), Expect = 0.013 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFL------NHEGYGIGDDLYSLSYDGCRK 356 WYYE+ + P V +++GWA+ + G G+GDDL+S +DG Sbjct: 673 WYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHL 732 Query: 357 LIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGR 397 A+ S + + D++ C +DL+ F +NG+ Sbjct: 733 WSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQ 773 >X70649-1|CAA49992.1| 740|Homo sapiens member of DEAD box protein family protein. Length = 740 Score = 49.6 bits (113), Expect = 3e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%) Query: 272 LNSHDVSEYLKISCNGLEARC-DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATK 330 +N +D I +GL + + + R T + G YYEV+ G+ ++GW+T Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTM 152 Query: 331 NSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDL-PEWQPGDILGCLIDLNTRE 389 + +G D + + G K K+ + E+ D +GC +D++ Sbjct: 153 QA------SLDLGTDKFGFGFGGTGK----KSHNKQFDNYGEEFTMHDTIGCYLDIDKGH 202 Query: 390 AIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTD 443 FS NG+ L FE K + +FNFG F FPP D Sbjct: 203 VKFSKNGKDLGLA---FEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKD 253 >EF418571-1|ABN70941.1| 740|Homo sapiens DEAD box polypeptide 1 protein. Length = 740 Score = 49.6 bits (113), Expect = 3e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%) Query: 272 LNSHDVSEYLKISCNGLEARC-DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATK 330 +N +D I +GL + + + R T + G YYEV+ G+ ++GW+T Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTM 152 Query: 331 NSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDL-PEWQPGDILGCLIDLNTRE 389 + +G D + + G K K+ + E+ D +GC +D++ Sbjct: 153 QA------SLDLGTDKFGFGFGGTGK----KSHNKQFDNYGEEFTMHDTIGCYLDIDKGH 202 Query: 390 AIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTD 443 FS NG+ L FE K + +FNFG F FPP D Sbjct: 203 VKFSKNGKDLGLA---FEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKD 253 >EF418570-1|ABN70940.1| 740|Homo sapiens DEAD box polypeptide 1 protein. Length = 740 Score = 49.6 bits (113), Expect = 3e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%) Query: 272 LNSHDVSEYLKISCNGLEARC-DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATK 330 +N +D I +GL + + + R T + G YYEV+ G+ ++GW+T Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTM 152 Query: 331 NSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDL-PEWQPGDILGCLIDLNTRE 389 + +G D + + G K K+ + E+ D +GC +D++ Sbjct: 153 QA------SLDLGTDKFGFGFGGTGK----KSHNKQFDNYGEEFTMHDTIGCYLDIDKGH 202 Query: 390 AIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTD 443 FS NG+ L FE K + +FNFG F FPP D Sbjct: 203 VKFSKNGKDLGLA---FEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKD 253 >BC053673-1|AAH53673.1| 740|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 protein. Length = 740 Score = 49.6 bits (113), Expect = 3e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%) Query: 272 LNSHDVSEYLKISCNGLEARC-DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATK 330 +N +D I +GL + + + R T + G YYEV+ G+ ++GW+T Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTM 152 Query: 331 NSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDL-PEWQPGDILGCLIDLNTRE 389 + +G D + + G K K+ + E+ D +GC +D++ Sbjct: 153 QA------SLDLGTDKFGFGFGGTGK----KSHNKQFDNYGEEFTMHDTIGCYLDIDKGH 202 Query: 390 AIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTD 443 FS NG+ L FE K + +FNFG F FPP D Sbjct: 203 VKFSKNGKDLGLA---FEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKD 253 >BC012132-1|AAH12132.1| 740|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 protein. Length = 740 Score = 49.6 bits (113), Expect = 3e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%) Query: 272 LNSHDVSEYLKISCNGLEARC-DSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATK 330 +N +D I +GL + + + R T + G YYEV+ G+ ++GW+T Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTM 152 Query: 331 NSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDL-PEWQPGDILGCLIDLNTRE 389 + +G D + + G K K+ + E+ D +GC +D++ Sbjct: 153 QA------SLDLGTDKFGFGFGGTGK----KSHNKQFDNYGEEFTMHDTIGCYLDIDKGH 202 Query: 390 AIFSLNGRCLTPCTEIFETTRCCKQGXXXXXXXXXXQQCRFNFGHLPFSFPPTD 443 FS NG+ L FE K + +FNFG F FPP D Sbjct: 203 VKFSKNGKDLGLA---FEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKD 253 >Z93020-1|CAI21594.1| 729|Homo sapiens RAN binding protein 9 protein. Length = 729 Score = 35.5 bits (78), Expect = 0.48 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Query: 260 YETVDM--TPINVILNSHDVSEYLKISCNGLEARCDSYS-----FESVRCTFQVDNGC-- 310 Y VD TP+ + D Y+ +S N L + SVR T + C Sbjct: 155 YPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGI 214 Query: 311 WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASV 367 +Y+EV IV+ G M IG + + + G+ D +S Y G + + Sbjct: 215 YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHGDDGHSFCSSGTGQP 270 Query: 368 QDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 P + GD++GC ++L ++ NG L Sbjct: 271 YG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 301 >BC052781-1|AAH52781.1| 802|Homo sapiens RANBP9 protein protein. Length = 802 Score = 35.5 bits (78), Expect = 0.48 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Query: 260 YETVDM--TPINVILNSHDVSEYLKISCNGLEARCDSYS-----FESVRCTFQVDNGC-- 310 Y VD TP+ + D Y+ +S N L + SVR T + C Sbjct: 228 YPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGI 287 Query: 311 WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASV 367 +Y+EV IV+ G M IG + + + G+ D +S Y G + + Sbjct: 288 YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHGDDGHSFCSSGTGQP 343 Query: 368 QDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 P + GD++GC ++L ++ NG L Sbjct: 344 YG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 374 >AL441883-5|CAI19841.1| 729|Homo sapiens RAN binding protein 9 protein. Length = 729 Score = 35.5 bits (78), Expect = 0.48 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Query: 260 YETVDM--TPINVILNSHDVSEYLKISCNGLEARCDSYS-----FESVRCTFQVDNGC-- 310 Y VD TP+ + D Y+ +S N L + SVR T + C Sbjct: 155 YPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGI 214 Query: 311 WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASV 367 +Y+EV IV+ G M IG + + + G+ D +S Y G + + Sbjct: 215 YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHGDDGHSFCSSGTGQP 270 Query: 368 QDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 P + GD++GC ++L ++ NG L Sbjct: 271 YG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 301 >AF064606-1|AAC17111.1| 243|Homo sapiens KB07 protein protein. Length = 243 Score = 35.5 bits (78), Expect = 0.48 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Query: 260 YETVDM--TPINVILNSHDVSEYLKISCNGLEARCDSYS-----FESVRCTFQVDNGC-- 310 Y VD TP+ + D Y+ +S N L + SVR T + C Sbjct: 6 YPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGI 65 Query: 311 WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASV 367 +Y+EV IV+ G M IG + + + G+ D +S Y G + + Sbjct: 66 YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHGDDGHSFCSSGTGQP 121 Query: 368 QDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 P + GD++GC ++L ++ NG L Sbjct: 122 YG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 152 >AB055311-1|BAB62525.1| 729|Homo sapiens RanBPM protein. Length = 729 Score = 35.5 bits (78), Expect = 0.48 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Query: 260 YETVDM--TPINVILNSHDVSEYLKISCNGLEARCDSYS-----FESVRCTFQVDNGC-- 310 Y VD TP+ + D Y+ +S N L + SVR T + C Sbjct: 155 YPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGI 214 Query: 311 WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASV 367 +Y+EV IV+ G M IG + + + G+ D +S Y G + + Sbjct: 215 YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHGDDGHSFCSSGTGQP 270 Query: 368 QDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 P + GD++GC ++L ++ NG L Sbjct: 271 YG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 301 >BC015936-1|AAH15936.1| 534|Homo sapiens ASH2L protein protein. Length = 534 Score = 34.3 bits (75), Expect = 1.1 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Query: 270 VILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTI--VTPG-VMQIG 326 V+L HD + LKIS + L + + VR + V G WY+E+T+ + P ++G Sbjct: 287 VLLALHDRAPQLKISDDRLTVVGEK-GYSMVRASHGVRKGAWYFEITVDEMPPDTAARLG 345 Query: 327 WATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDL 385 W S L + +G D +S S+ + ++++ + GD+LG I+L Sbjct: 346 W----SQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS--GYGQGDVLGFYINL 398 >AF056718-1|AAC13564.1| 628|Homo sapiens ash2l1 protein. Length = 628 Score = 34.3 bits (75), Expect = 1.1 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Query: 270 VILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTI--VTPG-VMQIG 326 V+L HD + LKIS + L + + VR + V G WY+E+T+ + P ++G Sbjct: 381 VLLALHDRAPQLKISDDRLTVVGEK-GYSMVRASHGVRKGAWYFEITVDEMPPDTAARLG 439 Query: 327 WATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDL 385 W S L + +G D +S S+ + ++++ + GD+LG I+L Sbjct: 440 W----SQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS--GYGQGDVLGFYINL 492 >AF056717-1|AAC13563.1| 501|Homo sapiens ash2l2 protein. Length = 501 Score = 34.3 bits (75), Expect = 1.1 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Query: 270 VILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTI--VTPG-VMQIG 326 V+L HD + LKIS + L + + VR + V G WY+E+T+ + P ++G Sbjct: 287 VLLALHDRAPQLKISDDRLTVVGEK-GYSMVRASHGVRKGAWYFEITVDEMPPDTAARLG 345 Query: 327 WATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDL 385 W S L + +G D +S S+ + ++++ + GD+LG I+L Sbjct: 346 W----SQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS--GYGQGDVLGFYINL 398 >AB022785-1|BAA74520.1| 628|Homo sapiens ASH2L protein. Length = 628 Score = 34.3 bits (75), Expect = 1.1 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Query: 270 VILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTI--VTPG-VMQIG 326 V+L HD + LKIS + L + + VR + V G WY+E+T+ + P ++G Sbjct: 381 VLLALHDRAPQLKISDDRLTVVGEK-GYSMVRASHGVRKGAWYFEITVDEMPPDTAARLG 439 Query: 327 WATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDL 385 W S L + +G D +S S+ + ++++ + GD+LG I+L Sbjct: 440 W----SQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS--GYGQGDVLGFYINL 492 >AB020982-1|BAA35127.1| 628|Homo sapiens ASH2L protein. Length = 628 Score = 34.3 bits (75), Expect = 1.1 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Query: 270 VILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTI--VTPG-VMQIG 326 V+L HD + LKIS + L + + VR + V G WY+E+T+ + P ++G Sbjct: 381 VLLALHDRAPQLKISDDRLTVVGEK-GYSMVRASHGVRKGAWYFEITVDEMPPDTAARLG 439 Query: 327 WATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDL 385 W S L + +G D +S S+ + ++++ + GD+LG I+L Sbjct: 440 W----SQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS--GYGQGDVLGFYINL 492 >BC019886-1|AAH19886.1| 486|Homo sapiens Unknown (protein for IMAGE:4419330) protein. Length = 486 Score = 33.9 bits (74), Expect = 1.5 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 38 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 93 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 94 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINNTCFYTKNGHSL 138 >BC121177-1|AAI21178.1| 620|Homo sapiens RAN binding protein 10 protein. Length = 620 Score = 33.1 bits (72), Expect = 2.6 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 89 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 144 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 145 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINGTCFYTKNGHSL 189 >BC121176-1|AAI21177.1| 620|Homo sapiens RAN binding protein 10 protein. Length = 620 Score = 33.1 bits (72), Expect = 2.6 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 89 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 144 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 145 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINGTCFYTKNGHSL 189 >BC099917-1|AAH99917.1| 620|Homo sapiens RAN binding protein 10 protein. Length = 620 Score = 33.1 bits (72), Expect = 2.6 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 89 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 144 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 145 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINGTCFYTKNGHSL 189 >AY337313-1|AAR01220.1| 620|Homo sapiens Ran-binding protein 10 protein. Length = 620 Score = 33.1 bits (72), Expect = 2.6 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 89 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 144 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 145 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINGTCFYTKNGHSL 189 >AB040897-1|BAA95988.1| 621|Homo sapiens KIAA1464 protein protein. Length = 621 Score = 33.1 bits (72), Expect = 2.6 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 299 SVRCTFQVDNGC--WYYEVTIVTPG---VMQIGWATKNSHFLNHEGYGIGDDLYSLSYDG 353 SVR T + C +Y+EV IV+ G M IG + + + G+ D +S Y G Sbjct: 90 SVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGW----DKHSYGYHG 145 Query: 354 CRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCL 399 + + P + GD++GC ++L ++ NG L Sbjct: 146 DDGHSFCSSGTGQPYG-PTFTTGDVIGCCVNLINGTCFYTKNGHSL 190 >M91455-1|AAA60295.1| 125|Homo sapiens ryanodine receptor protein. Length = 125 Score = 31.9 bits (69), Expect = 6.0 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 14/57 (24%) Query: 311 WYYEVTI--VTPGV------MQIGWATKNSHFLNH---EGYG---IGDDLYSLSYDG 353 WY+EV + VTP + +++GWA + EG+G +GDDLYS +DG Sbjct: 64 WYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDG 120 >BC104804-1|AAI04805.1| 950|Homo sapiens protocadherin alpha 9 protein. Length = 950 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >BC104802-1|AAI04803.1| 950|Homo sapiens protocadherin alpha 9 protein. Length = 950 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >AJ007610-1|CAC22257.1| 950|Homo sapiens protocadherin alpha 9 protein. Length = 950 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >AF152487-1|AAD43748.1| 842|Homo sapiens protocadherin alpha 9 short form protein protein. Length = 842 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >AF152317-1|AAD43711.1| 950|Homo sapiens protocadherin alpha 9 protein. Length = 950 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >AC005609-5|AAC34313.1| 842|Homo sapiens KIAA0345-like 5 protein. Length = 842 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 335 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 378 >AB002343-1|BAA20803.2| 845|Homo sapiens KIAA0345 protein. Length = 845 Score = 31.5 bits (68), Expect = 7.9 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 56 TLIASFVDNDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLD 99 TL+ VD ++ +P L +K + KE+ L V ++++VI LD Sbjct: 338 TLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLD 381 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.322 0.137 0.429 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 81,423,523 Number of Sequences: 224733 Number of extensions: 3377823 Number of successful extensions: 5896 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 5793 Number of HSP's gapped (non-prelim): 76 length of query: 546 length of database: 73,234,838 effective HSP length: 94 effective length of query: 452 effective length of database: 52,109,936 effective search space: 23553691072 effective search space used: 23553691072 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 68 (31.5 bits)
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