Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000705-TA|BGIBMGA000705-PA|IPR003929|Calcium-activated
BK potassium channel, alpha subunit
(1061 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5580D Cluster: PREDICTED: similar to potassium ... 653 0.0
UniRef50_Q1RKX5 Cluster: IP14110p; n=6; Endopterygota|Rep: IP141... 621 e-176
UniRef50_Q5VTN1 Cluster: Potassium channel, subfamily T, member ... 459 e-127
UniRef50_Q4RTZ8 Cluster: Chromosome 12 SCAF14996, whole genome s... 457 e-127
UniRef50_Q5JUK3 Cluster: Potassium channel subfamily T member 1;... 456 e-126
UniRef50_UPI0000ECB41D Cluster: potassium channel, subfamily T, ... 450 e-124
UniRef50_UPI000065F153 Cluster: Homolog of Homo sapiens "Sodium-... 405 e-111
UniRef50_A1Z878 Cluster: CG12904-PA; n=5; Coelomata|Rep: CG12904... 386 e-105
UniRef50_A7SU69 Cluster: Predicted protein; n=1; Nematostella ve... 355 3e-96
UniRef50_Q19190 Cluster: SLO-2 potassium channel; n=4; Caenorhab... 355 5e-96
UniRef50_Q3SY59 Cluster: KCNT2 protein; n=12; Euteleostomi|Rep: ... 304 7e-81
UniRef50_Q4SE07 Cluster: Chromosome 3 SCAF14626, whole genome sh... 298 4e-79
UniRef50_Q676B2 Cluster: Potassium channel subunit-like protein;... 198 9e-49
UniRef50_UPI000155C28E Cluster: PREDICTED: similar to potassium ... 168 6e-40
UniRef50_A0E804 Cluster: Chromosome undetermined scaffold_82, wh... 105 6e-21
UniRef50_A0CBF1 Cluster: Chromosome undetermined scaffold_164, w... 104 1e-20
UniRef50_Q22WQ5 Cluster: Transporter, cation channel family; n=1... 97 3e-18
UniRef50_Q22DT2 Cluster: Cation channel family protein; n=1; Tet... 95 1e-17
UniRef50_Q95V25 Cluster: Calcium-activated potassium channel slo... 94 2e-17
UniRef50_Q08460 Cluster: Calcium-activated potassium channel sub... 94 2e-17
UniRef50_Q86I16 Cluster: Similar to Y51A2D.19.p [Caenorhabditis ... 93 5e-17
UniRef50_Q12791 Cluster: Calcium-activated potassium channel sub... 92 8e-17
UniRef50_Q59FH2 Cluster: Large conductance calcium-activated pot... 91 1e-16
UniRef50_UPI0000E45FEB Cluster: PREDICTED: similar to calcium-ac... 89 6e-16
UniRef50_Q22T07 Cluster: Cation channel family protein; n=1; Tet... 88 1e-15
UniRef50_UPI0000F2B976 Cluster: PREDICTED: similar to potassium ... 85 1e-14
UniRef50_Q54SN1 Cluster: Ca-activated BK potassium channel, alph... 80 4e-13
UniRef50_Q03720-16 Cluster: Isoform L of Q03720 ; n=29; Neoptera... 78 1e-12
UniRef50_Q03720 Cluster: Calcium-activated potassium channel slo... 78 1e-12
UniRef50_Q22T08 Cluster: High conductance calcium-activated pota... 75 8e-12
UniRef50_Q38F65 Cluster: Calcium/potassium channel (CAKC), putat... 67 3e-09
UniRef50_O54982 Cluster: PH sensitive maxi K+ channel; n=13; Eut... 65 1e-08
UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family prot... 62 1e-07
UniRef50_Q55CU6 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-06
UniRef50_A0CYF6 Cluster: Chromosome undetermined scaffold_31, wh... 58 2e-06
UniRef50_Q6L2S2 Cluster: Potassium channel protein; n=1; Picroph... 48 0.001
UniRef50_A4HRK5 Cluster: Potassium channel subunit-like protein;... 42 0.068
UniRef50_A7AT63 Cluster: Putative uncharacterized protein; n=1; ... 42 0.089
UniRef50_Q9K7M1 Cluster: Potassium channel protein; n=1; Bacillu... 40 0.48
UniRef50_Q4D359 Cluster: Putative uncharacterized protein; n=2; ... 39 0.63
UniRef50_UPI00006CC471 Cluster: cation channel family protein; n... 38 1.1
UniRef50_Q929U4 Cluster: Lin2180 protein; n=13; Listeria|Rep: Li... 38 1.1
UniRef50_A0WA57 Cluster: Ion transport 2; n=1; Geobacter lovleyi... 38 1.1
UniRef50_A0BDF5 Cluster: Chromosome undetermined scaffold_100, w... 38 1.5
UniRef50_Q5KVS9 Cluster: Potassium channel protein; n=2; Geobaci... 37 2.5
UniRef50_Q9BJ49 Cluster: Putative uncharacterized protein; n=3; ... 36 4.4
UniRef50_Q3ADY6 Cluster: Formate dehydrogenase-O, iron-sulfur su... 36 5.9
UniRef50_O67715 Cluster: Potassium channel protein; n=1; Aquifex... 36 7.8
>UniRef50_UPI0000D5580D Cluster: PREDICTED: similar to potassium
channel, subfamily T, member 1; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to potassium channel,
subfamily T, member 1 - Tribolium castaneum
Length = 1384
Score = 653 bits (1613), Expect = 0.0
Identities = 335/482 (69%), Positives = 365/482 (75%), Gaps = 35/482 (7%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV
Sbjct: 272 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 331
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKD DL RARMNEAEACF+LAARNYADKT
Sbjct: 332 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDGDLARARMNEAEACFVLAARNYADKT 391
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AADEHTILRSWAVKDFAP VAQYVQIFRPENK+HVKFAE+VVCEDEFKYALLANNCTCPG
Sbjct: 392 AADEHTILRSWAVKDFAPNVAQYVQIFRPENKIHVKFAEYVVCEDEFKYALLANNCTCPG 451
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
ASTLVTLLLHTSRGQEGQQS EEWHRLYG+CSGNEIYHI LGDSRFFGEYEGKSFTYASF
Sbjct: 452 ASTLVTLLLHTSRGQEGQQSQEEWHRLYGRCSGNEIYHITLGDSRFFGEYEGKSFTYASF 511
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMK +DTCYYMSITKEENS+F V+++
Sbjct: 512 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKKSDTCYYMSITKEENSSFTVANQ 571
Query: 340 QAVPNPTIPKDQTACSFLSNERNPDEGSTSQQKKPDGSSVVQCEVPQVVLEXXXXXXXXX 399
P T ++ E +T DG+ PQ++L+
Sbjct: 572 ---PQGNNNNTSTEPVIVTAEEKSQAPATK-----DGTG-----SPQLILQ--------- 609
Query: 400 XXXRIKNLKTLSCANFNFASSKLADRSTSESRTCLKESPGIESVVDSHLLLPKP-ETSNF 458
+ T N + S+ + +S T + S+ +HL +P+ + N
Sbjct: 610 ----VPTCVTTFPDNAGLSDSRQCLKESSPGSTTID-----VSITGNHLDIPRSGDNPNL 660
Query: 459 LSPDTLSHRGGNSRRPSILPVPDMVTSSLTLTNDNQXXXXXXXXXXXXXXXXVPWRSPSE 518
LSP+ ++ R NSRRPSILPVPDM TSS N Q VPWRSPSE
Sbjct: 661 LSPEMINQR-RNSRRPSILPVPDMFTSS--SLNIPQDVADEGDESEDELEDDVPWRSPSE 717
Query: 519 KI 520
KI
Sbjct: 718 KI 719
Score = 380 bits (936), Expect = e-104
Identities = 196/267 (73%), Positives = 216/267 (80%), Gaps = 27/267 (10%)
Query: 666 SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLD 725
SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLD
Sbjct: 889 SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLD 948
Query: 726 TLLYQAFVKDYMITFVRLLLGIDQAPGSGFLASI-------KITKEDMWIRTYGRLYQKL 778
TLLYQAFVKDY+ITFVRLLLGIDQAPGSGFL S+ KITK+DMWIRTYGRLYQKL
Sbjct: 949 TLLYQAFVKDYVITFVRLLLGIDQAPGSGFLTSVSLFVKGMKITKDDMWIRTYGRLYQKL 1008
Query: 779 CSTSCEIPIGIYRTQDTSMADASHHQEELDGGDFPACGR-------------------QE 819
CST+CEIPIGIYRTQDTS++D+SH + +C R +E
Sbjct: 1009 CSTTCEIPIGIYRTQDTSLSDSSHVSMSAPSSAWSSCVRVPSLDEELGPDRVGVTYRPKE 1068
Query: 820 ATSCLGGCYGERTPVYSTSLADEARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDVSE 879
T+CL GC R ++S ++ADEA+DNH QQIERAEIANLVRSRMESLNL +DY+DVSE
Sbjct: 1069 GTNCL-GCTDRRNSMFSINMADEAKDNHEQQIERAEIANLVRSRMESLNLPTIDYNDVSE 1127
Query: 880 KRNSLSYVIINPSCDLNLQEGDIMNLV 906
KRNSLSYVIINPSCDL L+EGDI+ LV
Sbjct: 1128 KRNSLSYVIINPSCDLKLEEGDIIYLV 1154
Score = 247 bits (604), Expect = 1e-63
Identities = 111/125 (88%), Positives = 120/125 (96%), Gaps = 2/125 (1%)
Query: 542 WRNDFARI--VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQ 599
WR+ +I VKGFPPVSP+IGVSPTLC+LLKEKKPLCCLQLAQVCEHC+YRNA++YQWQ
Sbjct: 712 WRSPSEKIAIVKGFPPVSPYIGVSPTLCYLLKEKKPLCCLQLAQVCEHCSYRNARDYQWQ 771
Query: 600 NKTIILAADYASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWM 659
NKTIILAADYASNGIYNFIIPLRAHFRSKT+LNPIILLLERRPD+AFLDAISYFPLVYWM
Sbjct: 772 NKTIILAADYASNGIYNFIIPLRAHFRSKTSLNPIILLLERRPDIAFLDAISYFPLVYWM 831
Query: 660 LGTID 664
LGTID
Sbjct: 832 LGTID 836
Score = 95.9 bits (228), Expect = 5e-18
Identities = 52/86 (60%), Positives = 64/86 (74%), Gaps = 9/86 (10%)
Query: 936 SPTIITDFRGRSNSLRVVDDILLRRSNSLRQGISGTGSRRRKSSLEEIGISHFNSLLXXX 995
SPT+ RGRSNSLRV+DDILLRRSNSLRQG++ GS RRKSSLE+IG+SHF++
Sbjct: 1227 SPTVAGYQRGRSNSLRVIDDILLRRSNSLRQGLTSVGSGRRKSSLEDIGLSHFST----- 1281
Query: 996 XXXXXXDAIKLGLS-SIGLRITPPEE 1020
+ IK+ L+ SIGL +TPPEE
Sbjct: 1282 ---NYNNPIKIALNGSIGLEVTPPEE 1304
>UniRef50_Q1RKX5 Cluster: IP14110p; n=6; Endopterygota|Rep: IP14110p
- Drosophila melanogaster (Fruit fly)
Length = 736
Score = 621 bits (1534), Expect = e-176
Identities = 290/307 (94%), Positives = 295/307 (96%), Gaps = 1/307 (0%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQD+YVV
Sbjct: 367 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDFYVV 426
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKD DL RARMNEAEACFILAARNYADKT
Sbjct: 427 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDGDLARARMNEAEACFILAARNYADKT 486
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AADEHTILRSWAVKDFAP V QYVQIFRPE+KLHVKFAE VVCEDEFKYALLANNCTCPG
Sbjct: 487 AADEHTILRSWAVKDFAPNVPQYVQIFRPEHKLHVKFAEHVVCEDEFKYALLANNCTCPG 546
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF
Sbjct: 547 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 606
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
HSHRKYGVALVGVRPAELPEFYE+TILLNPGPRHIMK DTCYYMSITKEENSAFVV+
Sbjct: 607 HSHRKYGVALVGVRPAELPEFYEETILLNPGPRHIMKKDDTCYYMSITKEENSAFVVNQN 666
Query: 340 QAVPNPT 346
Q +PT
Sbjct: 667 Q-TSDPT 672
>UniRef50_Q5VTN1 Cluster: Potassium channel, subfamily T, member 2;
n=6; Tetrapoda|Rep: Potassium channel, subfamily T,
member 2 - Homo sapiens (Human)
Length = 1111
Score = 459 bits (1132), Expect = e-127
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 4e-59
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-26
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>UniRef50_Q4RTZ8 Cluster: Chromosome 12 SCAF14996, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 12
SCAF14996, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1260
Score = 457 bits (1127), Expect = e-127
Identities = 206/308 (66%), Positives = 251/308 (81%), Gaps = 12/308 (3%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FE+LA+ WME QKLGG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 308 FEELAYLWMESQKLGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 367
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R ILQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++RN D+T
Sbjct: 368 ILCPTEMDIQVRRILQIPLWSQRVIYLQGSALKDQDLMRAKMDDAEACFILSSRNEVDRT 427
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFA-------EFVVCEDEFKYALLA 212
AAD TILR+WA KDFAP YVQI +PENK HVKFA + VVCE+EFKYA+LA
Sbjct: 428 AADHQTILRAWAAKDFAPNCPLYVQILKPENKFHVKFAGKLFLLLDHVVCEEEFKYAMLA 487
Query: 213 NNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGK 272
NC CP STLVTLL+HTSRGQEGQ SPE+W R YG+CSGNE+YHI L DS+FFGEY+GK
Sbjct: 488 LNCVCPATSTLVTLLVHTSRGQEGQMSPEQWQRTYGRCSGNEVYHIRLCDSKFFGEYDGK 547
Query: 273 SFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENS 332
SFTYASFH+H+KYGV L+GV+ + +ILLNPGPRHIM +TDTCYY++ITKEENS
Sbjct: 548 SFTYASFHAHKKYGVCLIGVKRED-----NKSILLNPGPRHIMAATDTCYYINITKEENS 602
Query: 333 AFVVSDKQ 340
AF+ ++
Sbjct: 603 AFIFKQEE 610
Score = 150 bits (363), Expect = 2e-34
Identities = 66/115 (57%), Positives = 89/115 (77%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
VKG+PP SP+IG SPTLC LL +K P CCL+L + C H ++ +AK Y ++NK II++A+
Sbjct: 711 VKGYPPNSPYIGSSPTLCHLLPQKAPFCCLRLDKGCTHNSFEDAKAYGFKNKLIIVSAET 770
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++R + LNPI+LLL+ PD FL+AI FP+VY+M GTID
Sbjct: 771 AGNGLYNFIVPLRAYYRPRKELNPIVLLLDYPPDNHFLEAICCFPMVYFMTGTID 825
Score = 103 bits (247), Expect = 3e-20
Identities = 92/264 (34%), Positives = 125/264 (47%), Gaps = 64/264 (24%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKR------------------------EKERG 702
ITEL+ SNMRFMQFRA D Y+L LSK+EK E+++G
Sbjct: 901 ITELTHPSNMRFMQFRAKDCYSLALSKLEKVSLWTGNPLTCLHHFNDYFHFPFQIERDKG 960
Query: 703 SHISYMFRLPFAAGSVFSASMLDTLLY--------------------------QAFVKDY 736
S++++MFRLPFAAG VFS SMLDTLLY Q+FVKDY
Sbjct: 961 SNLAFMFRLPFAAGRVFSISMLDTLLYQVRLARERLDSCGVCVVVFLIQVSSPQSFVKDY 1020
Query: 737 MITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIPIGIYRTQDTS 796
MI VRLLLG+D PGSG+L + K +Y Q S + E +R + S
Sbjct: 1021 MIAIVRLLLGLDTTPGSGYLCACK--------DSYS---QSQLSVNAEHG-AEHRERGES 1068
Query: 797 MADASHHQEEL--DGGDFPACGRQEATSCLGGCYGERTPVYSTSLADEARDNHIQQIERA 854
+ + H+ D + P ++ P + R N ++ ER
Sbjct: 1069 WKEKTAHRNSTGSDQSEHPLLRKKSMQWARRLSRKSAKPSSRAERISQQRLNLYRRSERQ 1128
Query: 855 EIANLVRSRMESLNLTGVDYDDVS 878
E++ LV++RM+ L L V Y+DVS
Sbjct: 1129 ELSELVKNRMKHLGLPTVGYEDVS 1152
>UniRef50_Q5JUK3 Cluster: Potassium channel subfamily T member 1;
n=68; Eukaryota|Rep: Potassium channel subfamily T
member 1 - Homo sapiens (Human)
Length = 1230
Score = 456 bits (1124), Expect = e-126
Identities = 197/301 (65%), Positives = 250/301 (83%), Gaps = 5/301 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FE+L + WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 327 FEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 386
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M+ EACFIL++RN D+T
Sbjct: 387 ILCPTEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRT 446
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AAD TILR+WAVKDFAP YVQI +PENK HVKFA+ VVCE+E KYA+LA NC CP
Sbjct: 447 AADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPA 506
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQ+SPE+W R+YG+CSGNE+YHI +GDS+FF EYEGKSFTYA+F
Sbjct: 507 TSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAF 566
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+KYGV L+G++ + +ILLNPGPRHI+ ++DTC+Y++ITKEENSAF+ +
Sbjct: 567 HAHKKYGVCLIGLKRED-----NKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQE 621
Query: 340 Q 340
+
Sbjct: 622 E 622
Score = 204 bits (499), Expect = 8e-51
Identities = 93/126 (73%), Positives = 111/126 (88%)
Query: 668 TELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDTL 727
TEL+ SNMRFMQFRA D Y+L LSK+EKRE+E GS++++MFRLPFAAG VFS SMLDTL
Sbjct: 900 TELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRVFSISMLDTL 959
Query: 728 LYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIPI 787
LYQ+FVKDYMIT RLLLG+D PGSG+L ++KIT+ D+WIRTYGRL+QKLCS+S EIPI
Sbjct: 960 LYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPI 1019
Query: 788 GIYRTQ 793
GIYRT+
Sbjct: 1020 GIYRTE 1025
Score = 153 bits (370), Expect = 3e-35
Identities = 66/115 (57%), Positives = 91/115 (79%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
VKG+PP SP+IG SPTLC LL K P CCL+L + C+H +Y +AK Y ++NK II++A+
Sbjct: 731 VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAET 790
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++RS+ LNPI+LLL+ +PD FL+AI FP+VY+M G++D
Sbjct: 791 AGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVD 845
Score = 41.1 bits (92), Expect = 0.16
Identities = 22/53 (41%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 855 EIANLVRSR-MESLNLTGVDYDDVSEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ANL S M +NL G D++++ +N+LSYV+INP D L+ DI+ L+
Sbjct: 1143 DVANLTASDVMNRVNL-GYLQDEMNDHQNTLSYVLINPPPDTRLEPSDIVYLI 1194
>UniRef50_UPI0000ECB41D Cluster: potassium channel, subfamily T,
member 2; n=1; Gallus gallus|Rep: potassium channel,
subfamily T, member 2 - Gallus gallus
Length = 1201
Score = 450 bits (1108), Expect = e-124
Identities = 199/300 (66%), Positives = 246/300 (82%), Gaps = 5/300 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 247 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 306
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 307 ILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 366
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AAD TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 367 AADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 426
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQE QQS E+W ++YG+CSGNE++HI L +S FF EYEGKSFTYASF
Sbjct: 427 TSTLITLLVHTSRGQESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASF 486
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF +K
Sbjct: 487 HAHKKFGVCLIGVRKED-----NKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEK 541
Score = 224 bits (548), Expect = 9e-57
Identities = 128/279 (45%), Positives = 176/279 (63%), Gaps = 41/279 (14%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+E+GS++++MFRLPFAAG VFS SMLDT
Sbjct: 892 ITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDT 951
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASI----------KITKEDMWIRTYGRLYQ 776
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+ KIT+ED+WIRTY RLYQ
Sbjct: 952 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSVMEGKILFVQMKITEEDLWIRTYARLYQ 1011
Query: 777 KLCSTSCEIPIGIYRTQDTSMADA------------------------SHHQEEL--DGG 810
KLCS++ +IPIG+YRT+ + + S+H+ D
Sbjct: 1012 KLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQS 1071
Query: 811 DFPACGRQEATSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESL 867
D P R+ R P +S A+ + R N ++ ER E+A LV++RM+ L
Sbjct: 1072 DHPLLRRKSMQ--WARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHL 1129
Query: 868 NLTGVDYDDVSEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
L+ YD++++ +N+LSY++INPS D L+ DI+ L+
Sbjct: 1130 GLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLI 1168
Score = 159 bits (386), Expect = 4e-37
Identities = 69/117 (58%), Positives = 91/117 (77%)
Query: 548 RIVKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAA 607
R KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA
Sbjct: 722 RYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAA 781
Query: 608 DYASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
+ A NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 782 ETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 838
>UniRef50_UPI000065F153 Cluster: Homolog of Homo sapiens "Sodium-and
chloride-activated ATP-sensitive potassium channel; n=1;
Takifugu rubripes|Rep: Homolog of Homo sapiens
"Sodium-and chloride-activated ATP-sensitive potassium
channel - Takifugu rubripes
Length = 1289
Score = 405 bits (998), Expect = e-111
Identities = 195/324 (60%), Positives = 242/324 (74%), Gaps = 28/324 (8%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLAF WMERQK GG+YS +RAQ+EKHVV+C + L D +MDFLNEF+AHP LQDYYVV
Sbjct: 301 FEQLAFLWMERQKSGGNYSRYRAQTEKHVVLCVSCLKIDLLMDFLNEFFAHPRLQDYYVV 360
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRAR-------MNEAEACFILAA 152
+L P E+D +R +L VP+WAQRVIY+QGS LKD DL+RA+ M++AEACFIL+
Sbjct: 361 ILCPAEMDVQVRRVLHVPLWAQRVIYLQGSALKDQDLMRAKQVITTNMMDDAEACFILSN 420
Query: 153 RNYADKTAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAE-------------- 198
R D+ AAD TILR+WAVKDFAP YVQI +PENK HVKFAE
Sbjct: 421 RFEVDRIAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFAEVCLSPLFSFFSLPA 480
Query: 199 -FVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEGQQ-SPEEWHRLYGKCSGNEIY 256
VVCE+EFKYA+LA NC CPG STL+TLL+H+SRGQEG S ++WHR Y +CS NE++
Sbjct: 481 DHVVCEEEFKYAMLALNCVCPGTSTLITLLIHSSRGQEGGACSADQWHRTYRRCSANEVH 540
Query: 257 HIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMK 316
HI L +S+FFGEY+GKSFT+ASFH+H+K+GV L+GVR F ILLNPGP HIM
Sbjct: 541 HIRLEESKFFGEYQGKSFTFASFHAHKKFGVCLIGVR-----RFDTTNILLNPGPCHIMG 595
Query: 317 STDTCYYMSITKEENSAFVVSDKQ 340
++D C+Y++I+KEENSAFV ++
Sbjct: 596 ASDICFYINISKEENSAFVRGQRE 619
Score = 147 bits (357), Expect = 1e-33
Identities = 59/115 (51%), Positives = 91/115 (79%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
+KG+PP SP+IG SPTLC LL++K P CCL++ + C+H + +A+ Y ++NK I+++A+
Sbjct: 733 MKGYPPNSPYIGSSPTLCHLLQDKMPFCCLRMDKACQHTLFEDARSYGFKNKLILVSAEC 792
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++R + LNPI+LLLE P+ FL+AI +FP+V++ +G+ID
Sbjct: 793 AGNGLYNFIVPLRAYYRPRKELNPIVLLLESIPEADFLEAICWFPMVFYTVGSID 847
Score = 100 bits (239), Expect = 2e-19
Identities = 89/251 (35%), Positives = 121/251 (48%), Gaps = 54/251 (21%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEK----------------------REKERGSH 704
ITEL+ +NMRFMQFR D Y+L LSK+EK + E+GS+
Sbjct: 927 ITELTHPANMRFMQFRVKDHYSLALSKLEKVKVNYYLLMFIYAILYIQTSFSSKVEKGSN 986
Query: 705 ISYMFRLPFAAGSVFSASMLDTLLY-------------------QAFVKDYMITFVRLLL 745
+ +MFRLPFAAG VFS SMLDTLLY Q+FVKDYMI+ RLLL
Sbjct: 987 LVFMFRLPFAAGKVFSVSMLDTLLYQVLNRTRHSDSTFNCLLFSQSFVKDYMISITRLLL 1046
Query: 746 GIDQAPGSGFL--ASIKITKEDMWIRTYGRLYQKLCSTSCEIPIGIYRTQDTS--MADAS 801
G+D PGSGFL + + IT ED R + L S + G++R +S ++ +S
Sbjct: 1047 GLDSMPGSGFLCASQVSITVEDYEDTREPR--EPLLSRT-----GVHRNSTSSEPVSTSS 1099
Query: 802 HHQEE--LDGGDFPACGRQEATSCLGGCYGERTPVYSTSLADEARDNHIQQIERAEIANL 859
H + L R + P + + R ++ ER E+ L
Sbjct: 1100 HSSDHPLLRRKSMQWARRLSRKGGRSSSAAKGGPGSAAERISQQRLTLFRRSERQELNAL 1159
Query: 860 VRSRMESLNLT 870
VR+RM+ L L+
Sbjct: 1160 VRTRMKHLGLS 1170
>UniRef50_A1Z878 Cluster: CG12904-PA; n=5; Coelomata|Rep: CG12904-PA -
Drosophila melanogaster (Fruit fly)
Length = 1698
Score = 386 bits (951), Expect = e-105
Identities = 199/268 (74%), Positives = 215/268 (80%), Gaps = 27/268 (10%)
Query: 666 SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLD 725
SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAG+VFSASMLD
Sbjct: 1157 SITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGAVFSASMLD 1216
Query: 726 TLLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEI 785
TLLYQAFVKDY+ITFVRLLLGIDQAPGSGFL S++ITK+DMWIRTYGRLYQKLCST+CEI
Sbjct: 1217 TLLYQAFVKDYVITFVRLLLGIDQAPGSGFLTSMRITKDDMWIRTYGRLYQKLCSTTCEI 1276
Query: 786 PIGIYRTQDTSMADASHHQ-------------EELDGGDF--------------PACGRQ 818
PIGIYRTQDTS AD SH+ E L G + P RQ
Sbjct: 1277 PIGIYRTQDTSNADTSHYDEETGTPDSTKDSTEMLRGVTYRPPGSATGGASSFRPQPQRQ 1336
Query: 819 EATSCLGGCYGERTPVYSTSLADEARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDVS 878
+ +CLGGC + YS +LADEARDNH QQIERAEIANLVRSRMESLNL +DYDDVS
Sbjct: 1337 RSVNCLGGCSERKGSSYSINLADEARDNHAQQIERAEIANLVRSRMESLNLPTIDYDDVS 1396
Query: 879 EKRNSLSYVIINPSCDLNLQEGDIMNLV 906
EKRN LSYVIINPSCDL L+EGD++ LV
Sbjct: 1397 EKRNHLSYVIINPSCDLKLEEGDLIYLV 1424
Score = 361 bits (888), Expect = 6e-98
Identities = 176/195 (90%), Positives = 178/195 (91%), Gaps = 12/195 (6%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQD+YVV
Sbjct: 165 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDFYVV 224
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
LLSPMELDTTMRMILQ GSCLKD DL RARMNEAEACFILAARNYADKT
Sbjct: 225 LLSPMELDTTMRMILQ------------GSCLKDGDLARARMNEAEACFILAARNYADKT 272
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AADEHTILRSWAVKDFAP V QYVQIFRPE+KLHVKFAE VVCEDEFKYALLANNCTCPG
Sbjct: 273 AADEHTILRSWAVKDFAPNVPQYVQIFRPEHKLHVKFAEHVVCEDEFKYALLANNCTCPG 332
Query: 220 ASTLVTLLLHTSRGQ 234
ASTLVTLLLHTSRGQ
Sbjct: 333 ASTLVTLLLHTSRGQ 347
Score = 231 bits (566), Expect = 6e-59
Identities = 113/145 (77%), Positives = 120/145 (82%), Gaps = 22/145 (15%)
Query: 542 WRNDFARIVKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQV----------------- 584
W D++ IVKGFPPVSPFIGVSPTLC+LLKEKKPLCCLQLAQV
Sbjct: 960 WVYDYSCIVKGFPPVSPFIGVSPTLCYLLKEKKPLCCLQLAQVGSYDSPWAVQFHLEENQ 1019
Query: 585 -----CEHCAYRNAKEYQWQNKTIILAADYASNGIYNFIIPLRAHFRSKTTLNPIILLLE 639
CEHC+YRNAKEYQWQNKTIILAADYASNGIYNFIIPLRAHFRSKT+LNPIILLLE
Sbjct: 1020 SLSQVCEHCSYRNAKEYQWQNKTIILAADYASNGIYNFIIPLRAHFRSKTSLNPIILLLE 1079
Query: 640 RRPDVAFLDAISYFPLVYWMLGTID 664
RRPDVAFLDA+SYFPLVYWMLG+ID
Sbjct: 1080 RRPDVAFLDALSYFPLVYWMLGSID 1104
Score = 225 bits (551), Expect = 4e-57
Identities = 103/116 (88%), Positives = 107/116 (92%), Gaps = 1/116 (0%)
Query: 231 SRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALV 290
S +EGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALV
Sbjct: 381 SVAREGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALV 440
Query: 291 GVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDKQAVPNPT 346
GVRPAELPEFYE+TILLNPGPRHIMK DTCYYMSITKEENSAFVV+ Q +PT
Sbjct: 441 GVRPAELPEFYEETILLNPGPRHIMKKDDTCYYMSITKEENSAFVVNQNQ-TSDPT 495
Score = 85.4 bits (202), Expect = 7e-15
Identities = 53/101 (52%), Positives = 69/101 (68%), Gaps = 13/101 (12%)
Query: 936 SPTIITDFRGRSNSLRVVDDILLRRSNSLRQGIS--GTGSRRRKSSLEEIGISHFNSLLX 993
SPT++ + RGRSNSLR+ +DILLRRS+SLRQG+ G RRKSSLEEIGISHF +L+
Sbjct: 1525 SPTVVGNQRGRSNSLRIDNDILLRRSSSLRQGLPSVGVSHGRRKSSLEEIGISHFTTLM- 1583
Query: 994 XXXXXXXXDAIKLGLS-SIG------LRITPPEE-TPRMAL 1026
+ IK+ L+ SIG L++TPPEE TP + +
Sbjct: 1584 --QATNHSNPIKISLNGSIGMENQISLQVTPPEEPTPMLGV 1622
Score = 64.1 bits (149), Expect = 2e-08
Identities = 38/89 (42%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Query: 432 TCLKESPGIESVVDSHLLLPKPETSNFLSPDTLSHRGGNSRRPSILPVPDMVTSSLTLTN 491
T L +P + +HL +P N LSPD L+ R G SRRPSILPVPDM TSS + +
Sbjct: 694 TSLSITPATLTTTGNHLDVPFANNPNLLSPDVLNQRRG-SRRPSILPVPDMFTSS-SFSI 751
Query: 492 DNQXXXXXXXXXXXXXXXXVPWRSPSEKI 520
+PWRSPSEKI
Sbjct: 752 AGNDDGEEGDESDDEIDDEMPWRSPSEKI 780
>UniRef50_A7SU69 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 995
Score = 355 bits (874), Expect = 3e-96
Identities = 170/294 (57%), Positives = 216/294 (73%), Gaps = 6/294 (2%)
Query: 41 EQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVL 100
E+LAF RQK GG+Y+ A +++HVV+C+TTL T++DFLNEFYA L D +VVL
Sbjct: 298 ERLAFLLFSRQKEGGAYNHLLAGTDRHVVLCATTLRTGTLIDFLNEFYADSRLHDVHVVL 357
Query: 101 LSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTA 160
L P +LD+T+R++LQVP+WAQRV Y++GS L D DL+RAR N A CFILA R AD+ A
Sbjct: 358 LCPSDLDSTLRILLQVPVWAQRVTYLKGSALIDEDLVRARRNAA-GCFILADRYAADREA 416
Query: 161 ADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPGA 220
AD+HTILR+WA++DFAP +VQI +PENK HV FAE VVCEDE K+ALLA NC CPG
Sbjct: 417 ADQHTILRTWAIQDFAPATPLFVQILKPENKFHVSFAEHVVCEDEIKHALLAVNCVCPGI 476
Query: 221 STLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFH 280
STLVTLLLHT Q + S E+WH +YGKC+GNEIY I LGDS F Y KSFT+A+FH
Sbjct: 477 STLVTLLLHTLHEQYVRGS-EKWHEIYGKCAGNEIYDIRLGDSMIFRPYAYKSFTHAAFH 535
Query: 281 SHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAF 334
+H+KYGV L+GV+ ++LNPGP H M D C+Y++I+ EE++AF
Sbjct: 536 AHKKYGVTLIGVK----RHGKGGRLMLNPGPSHNMAYDDRCFYIAISSEEDTAF 585
Score = 167 bits (405), Expect = 2e-39
Identities = 78/133 (58%), Positives = 102/133 (76%), Gaps = 6/133 (4%)
Query: 667 ITELSQSSNMRFMQFRA--HDKYALHLSKMEKREKERGS----HISYMFRLPFAAGSVFS 720
I EL+ +SNMRFM+F+A H ++ + + KER H++YMFR PF+AG VFS
Sbjct: 863 IVELTYASNMRFMKFQAAPHHVTGESMASLRESTKERNKNSKDHLNYMFREPFSAGYVFS 922
Query: 721 ASMLDTLLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCS 780
SM+DTLLYQ FVKDYMIT + LLLG +Q+PGSG+L S+KIT + +W+ TYGRL+Q+LCS
Sbjct: 923 MSMIDTLLYQTFVKDYMITLISLLLGCEQSPGSGYLCSLKITADHLWLGTYGRLFQRLCS 982
Query: 781 TSCEIPIGIYRTQ 793
T+CEIPIG+YRTQ
Sbjct: 983 TTCEIPIGVYRTQ 995
Score = 114 bits (274), Expect = 1e-23
Identities = 53/116 (45%), Positives = 80/116 (68%), Gaps = 1/116 (0%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNA-KEYQWQNKTIILAAD 608
+ G PVSP+IG +P C L + KP CCL+L + CEH ++ + ++ Q+ II+++
Sbjct: 691 IVGVLPVSPYIGRTPMRCHLYQTPKPFCCLRLNEDCEHREMSDSVRMHRQQHGGIIVSSP 750
Query: 609 YASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A G+YNFI+PLRA+ R K TL PIILLL P+ FL+A+ +FP++Y+M+GTI+
Sbjct: 751 VAEAGLYNFILPLRAYHRPKITLKPIILLLGEEPNEDFLEAVCHFPMLYYMVGTIN 806
>UniRef50_Q19190 Cluster: SLO-2 potassium channel; n=4;
Caenorhabditis|Rep: SLO-2 potassium channel -
Caenorhabditis elegans
Length = 1107
Score = 355 bits (872), Expect = 5e-96
Identities = 166/291 (57%), Positives = 210/291 (72%), Gaps = 5/291 (1%)
Query: 41 EQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVL 100
++L TW ERQK G +SS E HVVV TTL + I DFL EFYAHP Q +VL
Sbjct: 296 DELGQTWSERQKSGTDFSSWNGV-ESHVVVTITTLEVEFIRDFLEEFYAHPENQRIQIVL 354
Query: 101 LSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTA 160
LSP ELD RM+L++P+W RV Y++GS L+D DL RA + ++ACFIL+AR+ K A
Sbjct: 355 LSPAELDNQTRMLLKIPLWNNRVHYVRGSSLRDEDLERANVATSKACFILSARHVNRKVA 414
Query: 161 ADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPGA 220
DEHTILRSWA+KDFAP V QYVQIFR E K+H++ AE ++CEDEFKYALLANNC CPG
Sbjct: 415 TDEHTILRSWAIKDFAPNVKQYVQIFRAETKMHIEHAEVLICEDEFKYALLANNCICPGI 474
Query: 221 STLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFH 280
ST +TLL+HTSRG+EGQ+S E WH++YG SGNE+Y I + DS+FF EY GKSF+ SFH
Sbjct: 475 STFITLLMHTSRGEEGQKSTEPWHKVYGFHSGNEMYQIKVQDSKFFCEYVGKSFSSTSFH 534
Query: 281 SHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEEN 331
+H++YG+ L+ V P+ + LNPG HI++ TDT YYM +T EE+
Sbjct: 535 AHKEYGIGLIAVS----PDGDTSRMKLNPGSSHIIQPTDTVYYMGLTNEES 581
Score = 173 bits (422), Expect = 2e-41
Identities = 77/127 (60%), Positives = 101/127 (79%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ ++NMRF+QF H+ Y+L S+ EK+E++RGSH+ +MFRLPFA G VFSA+MLD
Sbjct: 856 ITELTHATNMRFVQFNPHNAYSLAQSRFEKKERKRGSHMPFMFRLPFAQGGVFSANMLDR 915
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQA +K +++ VRLLLGIDQ G+L S IT +D+WIR YGRLYQKLCS+ +IP
Sbjct: 916 LLYQAIIKPFVVDLVRLLLGIDQHSDGGYLTSFVITSDDLWIRNYGRLYQKLCSSVADIP 975
Query: 787 IGIYRTQ 793
IGI+RT+
Sbjct: 976 IGIFRTK 982
Score = 130 bits (313), Expect = 3e-28
Identities = 60/120 (50%), Positives = 85/120 (70%), Gaps = 4/120 (3%)
Query: 548 RIVKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAA 607
++ + +P V +IG S T+C ++KE++ LCCL+L + C H + +A EYQW+N+ IILAA
Sbjct: 684 KLQRTYPQVRTYIGTSNTVCHMMKERRSLCCLKLDEKCAHKSATSAHEYQWRNRPIILAA 743
Query: 608 DYASNGIYNFIIPLRAHFRSKTTLNPIILLLERRP----DVAFLDAISYFPLVYWMLGTI 663
D S+G+YN +IPLRA++R L+PII+LLE + AFLDAISYFP VYWM G +
Sbjct: 744 DRTSSGMYNLVIPLRAYYRPVHDLHPIIILLELEEQDSLNDAFLDAISYFPDVYWMKGKV 803
Score = 42.3 bits (95), Expect = 0.068
Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Query: 832 TPVYSTSLADEARDNHIQQIER-AEIANLVRSRMESLNLTGVD-YDDVSEKRNSLSYVII 889
T S L ++ +D ++ R ++ + V++RM LN+ + S++++ +SYVII
Sbjct: 986 TKTVSLDLQEQCKDFENTEMGRNKDMYDHVKNRMRLLNIKDTHTLLEGSDEKSQISYVII 1045
Query: 890 NPSCDLNLQEGDIMNLV 906
NP+ DL L+ GDI+ ++
Sbjct: 1046 NPAQDLELESGDIVYVI 1062
>UniRef50_Q3SY59 Cluster: KCNT2 protein; n=12; Euteleostomi|Rep:
KCNT2 protein - Homo sapiens (Human)
Length = 1068
Score = 304 bits (747), Expect = 7e-81
Identities = 133/197 (67%), Positives = 165/197 (83%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEG 236
STL+TLL+HTSRGQ G
Sbjct: 454 TSTLITLLVHTSRGQFG 470
Score = 203 bits (496), Expect = 2e-50
Identities = 120/276 (43%), Positives = 170/276 (61%), Gaps = 38/276 (13%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 762 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 821
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLY----------- 775
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLY
Sbjct: 822 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 881
Query: 776 --------QKLCSTSC-------EIPIGIYRTQDTSMA-DASHHQEE------LDGGDFP 813
QKL ++ +I I + +DT + + HH+ D D P
Sbjct: 882 IGIYRTESQKLTTSESRKIASQSQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHP 941
Query: 814 ACGRQEATSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLT 870
R+ + P +S A+ + R N ++ ER E+A LV++RM+ L L+
Sbjct: 942 LLRRKSMQWARR--LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLS 999
Query: 871 GVDYDDVSEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
V YD++++ +++LSY++INPS D ++ D++ L+
Sbjct: 1000 TVGYDEMNDHQSTLSYILINPSPDTRIELNDVVYLI 1035
Score = 124 bits (298), Expect = 2e-26
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 619 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 678
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 679 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 711
Score = 68.1 bits (159), Expect = 1e-09
Identities = 34/64 (53%), Positives = 43/64 (67%), Gaps = 5/64 (7%)
Query: 281 SHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDKQ 340
S ++GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+Q
Sbjct: 465 SRGQFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQQ 519
Query: 341 AVPN 344
N
Sbjct: 520 RKSN 523
>UniRef50_Q4SE07 Cluster: Chromosome 3 SCAF14626, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14626, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1083
Score = 298 bits (732), Expect = 4e-79
Identities = 134/197 (68%), Positives = 160/197 (81%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLAF WMERQK GG+YS +RAQ+EKHVV+C + L D +MDFLNEF+AHP LQDYYVV
Sbjct: 244 FEQLAFLWMERQKSGGNYSRYRAQTEKHVVLCVSCLKIDLLMDFLNEFFAHPRLQDYYVV 303
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +L VP+WAQRVIY+QGS LKD DL+RA+M++AEACFIL+ R D+
Sbjct: 304 ILCPAEMDVQVRRVLHVPLWAQRVIYLQGSALKDQDLMRAKMDDAEACFILSNRFEVDRI 363
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AAD TILR+WAVKDFAP YVQI +PENK HVKFA VCE+EFKYA+LA NC CPG
Sbjct: 364 AADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFAVMCVCEEEFKYAMLALNCVCPG 423
Query: 220 ASTLVTLLLHTSRGQEG 236
STL+TLL+H+SRGQ G
Sbjct: 424 TSTLITLLIHSSRGQYG 440
Score = 164 bits (398), Expect = 1e-38
Identities = 72/98 (73%), Positives = 89/98 (90%)
Query: 696 KREKERGSHISYMFRLPFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLLGIDQAPGSGF 755
++E+ERGS++ +MFRLPFAAG VFS SMLDTLLYQ+FVKDYMI+ RLLLG+D PGSGF
Sbjct: 874 QKERERGSNLVFMFRLPFAAGKVFSVSMLDTLLYQSFVKDYMISITRLLLGLDSMPGSGF 933
Query: 756 LASIKITKEDMWIRTYGRLYQKLCSTSCEIPIGIYRTQ 793
L ++KIT++D+WIRTYGRLYQKLCST+ +IPIGIYRT+
Sbjct: 934 LCAMKITEDDLWIRTYGRLYQKLCSTNGDIPIGIYRTE 971
Score = 147 bits (357), Expect = 1e-33
Identities = 60/115 (52%), Positives = 91/115 (79%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
+KG+PP SP+IG SPTLC LL++K P CCL++ + C+H + +A+ Y ++NK II++A+
Sbjct: 626 MKGYPPNSPYIGSSPTLCHLLQDKMPFCCLRMDKACQHTLFEDARSYGFKNKLIIVSAES 685
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++R + LNPI+LLLE P+ FL+AI +FP+V++ +G+ID
Sbjct: 686 AGNGLYNFIVPLRAYYRPRKELNPIMLLLESIPEADFLEAICWFPMVFYTVGSID 740
Score = 63.7 bits (148), Expect = 3e-08
Identities = 34/62 (54%), Positives = 42/62 (67%), Gaps = 6/62 (9%)
Query: 280 HSHR-KYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSD 338
HS R +YGV L+GVR F ILLNPGP HIM ++D C Y++I+KEENSAFV
Sbjct: 433 HSSRGQYGVCLIGVR-----RFDTTNILLNPGPCHIMGASDLCSYINISKEENSAFVRGQ 487
Query: 339 KQ 340
K+
Sbjct: 488 KE 489
Score = 43.6 bits (98), Expect = 0.029
Identities = 19/30 (63%), Positives = 24/30 (80%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEK 696
ITEL+ +NMRFMQF+ D Y+L LSK+EK
Sbjct: 794 ITELTHPANMRFMQFKVKDHYSLALSKLEK 823
>UniRef50_Q676B2 Cluster: Potassium channel subunit-like protein;
n=1; Oikopleura dioica|Rep: Potassium channel
subunit-like protein - Oikopleura dioica (Tunicate)
Length = 969
Score = 198 bits (482), Expect = 9e-49
Identities = 125/337 (37%), Positives = 182/337 (54%), Gaps = 23/337 (6%)
Query: 41 EQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFY-AHPLLQDYYVV 99
EQ+A ++E+Q+L +R +S KHVV C+T L D ++ FL+EFY ++Y VV
Sbjct: 300 EQIAVIYLEQQRL----VEYR-ESRKHVVFCTTDLQYDDVVVFLHEFYEVDEHAENYSVV 354
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARN----Y 155
L E D +++ LQ P+ V I GS + DL+RAR+N+A A FI R
Sbjct: 355 LFVAKEPDASVKRFLQAPL----VTLIIGSTYRSDDLLRARLNDALAVFISTDRTRRGGV 410
Query: 156 ADKTAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNC 215
+ DEHT+LRS A+KDFAP +VQ R E+ ++ FA+ +C+DE KYALLA NC
Sbjct: 411 LSRAETDEHTVLRSMAIKDFAPSTKLFVQCLRSESTFYLGFADNCLCDDEMKYALLALNC 470
Query: 216 TCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFT 275
PG ST +TLL+HT++G + +W + +G EIY ++ +S+FF Y G SF
Sbjct: 471 DIPGMSTFITLLIHTTKGLD-DDIHGDWKVHVNRSAGMEIYDVLASESKFFKTYIGLSFP 529
Query: 276 YASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFV 335
AS HRK G L+ V + + LNPG + D YY+ +T E +SAF+
Sbjct: 530 QASCVVHRKTGAILMAVE-------RDGKLKLNPGQGFHICPEDRLYYVCLTDEGDSAFI 582
Query: 336 VSDKQAVPNPTIPKDQTACSFLSNERNPDEGSTSQQK 372
+ T K A + S + +P +G S Q+
Sbjct: 583 DDHMDDLGEVTTSKIGFA-AINSTKSSPTDGEKSFQQ 618
Score = 97.1 bits (231), Expect = 2e-18
Identities = 96/338 (28%), Positives = 149/338 (44%), Gaps = 40/338 (11%)
Query: 553 FPPVSPFIG-VSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYAS 611
FPP +P++G ++PTLC++ KE E N E W II++A+ A
Sbjct: 642 FPPCTPYLGYITPTLCYIRKEPAS---------AEEMLLGNVWEKTWPASHIIVSAEEAQ 692
Query: 612 NGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTIDWSITELS 671
+YNFIIPLRA++RS L PI+LLLE+ P +FL+ IS+FPLVY+ G+ S+ +L
Sbjct: 693 KALYNFIIPLRAYYRSVDELRPIVLLLEKEPSQSFLECISWFPLVYYQTGSCT-SVDDLL 751
Query: 672 QSSNM-RFMQFRAHDKYALHLSKMEKREKERGSHI---SYMFRLPFAAGSVFSASMLDTL 727
+S + + + +LS ME+ + + RL A S +
Sbjct: 752 KSGILWAHSVIILNRDLSSNLSSMEEEHMADSKQLIATETICRLFPAVNVSLELSYASNM 811
Query: 728 LYQAF----VKDYMITFVRLLLGIDQAP---GSGFLASI-------KITKEDMWIR---- 769
+ F KD + L + + P G F +S+ TK + R
Sbjct: 812 RFMNFSLQNEKDDAVQGTNELSYLFRGPFASGRAFCSSMLDALLYQSFTKVTVTEREASL 871
Query: 770 TYGRLYQKLCSTSCEIPIGIYRTQDTSMADASHHQEELDGGDFPACGRQEATSCLGGCYG 829
Y +L++ L + EIP+GIYR + D Q D EA CL
Sbjct: 872 NYSQLFKILTQFTGEIPLGIYRNE--KRTDFCSSQTRKASSDRSMDTMNEADDCLNNPRA 929
Query: 830 ERTPVYSTSLADEARDNHIQQIERAEIANLVRSRMESL 867
E P+ + D+ +N I+Q R + + +ME +
Sbjct: 930 E--PLRMRTERDQL-NNLIEQ--RTKYLKVPSEKMEEV 962
>UniRef50_UPI000155C28E Cluster: PREDICTED: similar to potassium
channel, subfamily T, member 2; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to potassium channel,
subfamily T, member 2 - Ornithorhynchus anatinus
Length = 541
Score = 168 bits (409), Expect = 6e-40
Identities = 98/228 (42%), Positives = 140/228 (61%), Gaps = 31/228 (13%)
Query: 696 KREKERGSHISYMFRLPFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLLGIDQAPGSGF 755
++E+E+GS++++MFRLPFAAG VFS SMLDTLLYQ+FVKDYMI+ RLLLG+D PGSGF
Sbjct: 146 QKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGF 205
Query: 756 LASIKITKEDMWIRTYGRLYQKLCSTSCEIPIGIYRTQD----TSMADAS---------- 801
L S+KIT++D+WIRTY RLYQKLCS++ +IPIGIYRT+ TS + S
Sbjct: 206 LCSMKITEDDLWIRTYARLYQKLCSSTGDIPIGIYRTESQKLTTSESQISISVEEWEDTK 265
Query: 802 ------HHQE------ELDGGDFPACGRQEATSCLGGCYGERTPVYSTSLAD---EARDN 846
HH+ D D P R+ + P +S A+ + R N
Sbjct: 266 DTKEPIHHRNNHRNSTSSDQSDHPLLRRKSMQ--WARRLSRKVPKHSGKTAEKISQQRLN 323
Query: 847 HIQQIERAEIANLVRSRMESLNLTGVDYDDVSEKRNSLSYVIINPSCD 894
++ ER E+A LV++RM+ L L+ YD++ + + L++++ + D
Sbjct: 324 LYRRSERQELAELVKNRMKHLGLSTAGYDELGDHCSRLTHLVCTTAED 371
Score = 93.5 bits (222), Expect = 3e-17
Identities = 40/55 (72%), Positives = 47/55 (85%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQ 94
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQ
Sbjct: 92 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQ 146
>UniRef50_A0E804 Cluster: Chromosome undetermined scaffold_82, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_82,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1140
Score = 105 bits (252), Expect = 6e-21
Identities = 85/265 (32%), Positives = 130/265 (49%), Gaps = 28/265 (10%)
Query: 62 AQSEKHVVVCSTTLHADTIMDFLNEFYA--HPLLQDYYVVLLSPMELDTTMRMILQVPIW 119
+Q+ H+V+ T + + +F E + H L Q + ++L P D + ++Q P +
Sbjct: 253 SQAVPHIVILGT-ISLNAAENFFKELFHEDHGLAQKH-AIILCPQRPDVNLESLIQQPEY 310
Query: 120 AQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDF---- 175
+ VIYIQG D DL R ++ +A+A I+ + +D TA D TIL + +K +
Sbjct: 311 SN-VIYIQGDPHLDKDLKRCQIEKAKAIIIMCNKQSSDPTAEDSKTILLAIVIKSYLKQH 369
Query: 176 ---APKVAQYVQIFRPENKLHV-----KFAEF--VVCEDEFKYALLANNCTCPGASTLVT 225
K+ +QI R E K H K +F V+C +E K +LLA +C CPG ++
Sbjct: 370 NTTGVKIRFCMQILRQEGKTHYFLSLNKQTKFDQVICIEELKMSLLAKSCLCPGLIAFIS 429
Query: 226 LLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKY 285
L+ TS G P++W Y G EIY +L FF GKSFT ++++
Sbjct: 430 NLI-TSSGNP-PNLPQKWLNEYWIGQGFEIYKTLL--PNFF---RGKSFTQTVLILYKQF 482
Query: 286 GVALVGVRPAELPEFYEDTILLNPG 310
V L G+ + P YE LLNPG
Sbjct: 483 QVILFGIEISS-PNDYEKN-LLNPG 505
Score = 36.7 bits (81), Expect = 3.4
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 614 IYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGT 662
+ NFI+PLR+ + T PI++L ++ P I YFP +Y++ GT
Sbjct: 718 LINFILPLRSKYL--ITYPPIVILNDQEPSEKQWAQICYFPEIYFVKGT 764
>UniRef50_A0CBF1 Cluster: Chromosome undetermined scaffold_164,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_164,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1039
Score = 104 bits (249), Expect = 1e-20
Identities = 80/284 (28%), Positives = 142/284 (50%), Gaps = 24/284 (8%)
Query: 67 HVVVCSTTLHADTIMDFLNE-FYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVIY 125
H+++CS + ++ +F NE F+ QD ++L P +T M L + +IY
Sbjct: 282 HIIICSY-VSVPSLKNFCNELFHQDHGGQDKNAIILKPSIPNTEMEDFLHNERYEMFLIY 340
Query: 126 IQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAP-----KVA 180
+QG+ + + DL RA + +A+AC IL + D +AD IL +K + +
Sbjct: 341 LQGNPMVERDLRRAAVTQAKACVILTNKQIVDSHSADHKNILIGLLIKKYVNHLTGCNIR 400
Query: 181 QYVQIFRPENKLHVK-------FAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRG 233
+Q+ +PE+K+H K + ++ +EFK LLA +C CPG +L+ L+ TS G
Sbjct: 401 LCMQLIKPESKMHYKQSLGVKMITDQIIVVEEFKMNLLAKSCFCPGIISLLGNLV-TSAG 459
Query: 234 QEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVR 293
++ + EW Y G+EIY D F +++GK+F+ + + ++ L G+
Sbjct: 460 EQKESLDSEWLTQYTDGMGHEIYRT---DLSF--KFQGKTFSEVAAIVYNEFSGILFGL- 513
Query: 294 PAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVS 337
EL + I LNPG +I+ +T + I +++ A +V+
Sbjct: 514 --ELDFEKQPIIRLNPGV-YIITNTKKVHAYIICQDKKVADLVA 554
Score = 41.9 bits (94), Expect = 0.089
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 16/152 (10%)
Query: 67 HVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVIYI 126
H+VVC +H +I FL A L + YVV+L+P + I + P +V ++
Sbjct: 634 HIVVCG--IHP-SIYYFLLPLRAKYLKEIQYVVILAPEKPTEIWEQINRFP----KVKFV 686
Query: 127 QGSCLKDTDLIRARMNEAEACFILAARNYADKTAA--------DEHTILRSWAVKDFAPK 178
QGS L DL RA ++ A+ I A + A+KT + D +I A+K P
Sbjct: 687 QGSPLISEDLQRASIHCADKAVIFAQSSDANKTESEDFLDQMHDAESIFIYKAIKKINPS 746
Query: 179 VAQYVQIFRPENKLHVKFAEFVVCEDEFKYAL 210
+ +++ N + ++ +++FKY L
Sbjct: 747 IQIMIELVSSSNIQFLLDKDYKF-QNDFKYEL 777
>UniRef50_Q22WQ5 Cluster: Transporter, cation channel family; n=1;
Tetrahymena thermophila SB210|Rep: Transporter, cation
channel family - Tetrahymena thermophila SB210
Length = 1181
Score = 96.7 bits (230), Expect = 3e-18
Identities = 78/288 (27%), Positives = 130/288 (45%), Gaps = 24/288 (8%)
Query: 63 QSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQR 122
+S HVVV F F+ Q + +LL P D + +L P
Sbjct: 334 ESVSHVVVTGVVSSTAAENFFQELFHQDHGDQAKHALLLLPHAPDGQLENLLSNP----N 389
Query: 123 VIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQY 182
+ Y++G D DL R ++ +A++ IL + +D D TILR+ +K + ++
Sbjct: 390 LFYMEGQPSNDNDLKRCQLEKAKSVIILCNKQSSDPHWEDSQTILRAMDMKKYLKSNIRF 449
Query: 183 -VQIFRPENKLHVKFA---------EFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSR 232
Q+ R E K H + + V+C +E K +LLA +C CPG LV L+ TS
Sbjct: 450 CTQLLRQEGKTHYYLSLQETQSEQIDQVICIEELKMSLLAKSCLCPGLIALVNNLI-TSS 508
Query: 233 GQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGV 292
G +W Y K G EIY ++L +Y+G++F+ A+ ++ Y L G+
Sbjct: 509 GSPTDNLEYKWLEDYWKGQGFEIYKVLLSH-----KYQGRTFSQAALSIYKNYKAILFGL 563
Query: 293 RPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDKQ 340
EL + LNPG +I + + Y+ I +++ +A +S +
Sbjct: 564 ---ELISTESSRLFLNPGSMYIPSTYEVIGYI-IAEDKETADNISQSK 607
>UniRef50_Q22DT2 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1047
Score = 94.7 bits (225), Expect = 1e-17
Identities = 75/322 (23%), Positives = 145/322 (45%), Gaps = 24/322 (7%)
Query: 67 HVVVCSTTLHADTIMDFLNE-FYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVIY 125
H+++C + + F NE F+ QD ++L + M + L + + Y
Sbjct: 310 HIIICGH-VDVSALRFFCNELFHEDHGNQDKNAIILQSNIPSSEMELFLNNQQYEHNLTY 368
Query: 126 IQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQY--- 182
+QG+ + DL RA +A+ C I+ + D T++D I+ +K + +
Sbjct: 369 LQGNPKTERDLKRAAATKAKTCVIMINKYSGDSTSSDHKNIMTGLCIKKIVYHLTRNNLN 428
Query: 183 --VQIFRPENKLHV------KFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQ 234
+Q+ +PE+K H K + ++ +E K LLA +C CPG +L+ L+ ++ +
Sbjct: 429 LCMQLIKPESKFHYLSALSQKSTDQLIVVEEIKMNLLAKSCFCPGIISLIGNLIQSTSAE 488
Query: 235 EGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVRP 294
P +W R Y G+E+Y L + + G++F+ + + K+ L+G+
Sbjct: 489 VTDNEPTKWIREYKNGLGHEMYRTTLSVT-----FSGQTFSTIAAKVYEKFQAILLGM-- 541
Query: 295 AELPEFYEDTILLNPGPRHIMKST--DTCYYMSITKEENSAFVVSDKQAVPNPTIPKDQT 352
E+ + I LNPG +I+++T + + I +++N A V+ Q I +Q
Sbjct: 542 -EIDIEGQTVIRLNPG-SYIVRNTPENNVHVYIICEDKNVADKVASYQMSAQDLIEFNQK 599
Query: 353 ACSFLSNERNPDEGSTSQQKKP 374
E+N + S ++P
Sbjct: 600 KLLHQKKEKNETQAFESDYQQP 621
Score = 35.9 bits (79), Expect = 5.9
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 11/90 (12%)
Query: 713 FAAGSVFSASMLDTLLYQAFVKDYMIT-FVRLLLGIDQAPGSGFLASI-KITKEDMW--- 767
+AAG V+ ++M+D L Q F +++T F ++L G + + I KI + ++W
Sbjct: 807 YAAGEVYISTMVDALTCQTFYNPHILTIFQQILTGGNHSQEQSLNNEIDKIKQSNLWQIP 866
Query: 768 ------IRTYGRLYQKLCSTSCEIPIGIYR 791
+T+G+L+ L I +G+YR
Sbjct: 867 VPEDYYNKTFGQLFHYLSEQRDLIALGLYR 896
>UniRef50_Q95V25 Cluster: Calcium-activated potassium channel slo-1;
n=4; Bilateria|Rep: Calcium-activated potassium channel
slo-1 - Caenorhabditis elegans
Length = 1140
Score = 94.3 bits (224), Expect = 2e-17
Identities = 74/290 (25%), Positives = 134/290 (46%), Gaps = 21/290 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQ-DYYVVLLSPMELDT 108
RQK GG Y + KH+VVC + D++ FL +F D VV L + D
Sbjct: 358 RQKYGGEYKGEHGK--KHIVVCGHITY-DSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDL 414
Query: 109 TMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILR 168
+ + + +V + G+ + DL R ++ +A+AC +LA + + A D I+R
Sbjct: 415 ELEGLFKRHF--TKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMR 472
Query: 169 SWAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGA 220
++K+++ + VQ+ + NK ++ K + V+C E K +A +C PG
Sbjct: 473 VISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGF 532
Query: 221 STLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFH 280
ST++ L R + Q+ +W LY +G E+Y L S + G +F A
Sbjct: 533 STMMANLF-AMRSFKTSQTTPDWLNLYLCGAGMEMYTDTLSHS-----FVGMTFPEAVDL 586
Query: 281 SHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEE 330
+ G+ L+ + + E E I +NPGP +++ ++++ + +E
Sbjct: 587 LFNRLGLLLLAIELKD-EENKECNIAINPGPHIVIQPQTQGFFIAQSADE 635
>UniRef50_Q08460 Cluster: Calcium-activated potassium channel
subunit alpha-1 (Calcium-activated potassium channel,
subfamily M subunit alpha-1) (Maxi K channel) (MaxiK)
(BK channel) (K(VCA)alpha); n=87; Coelomata|Rep:
Calcium-activated potassium channel subunit alpha-1
(Calcium-activated potassium channel, subfamily M
subunit alpha-1) (Maxi K channel) (MaxiK) (BK channel)
(K(VCA)alpha) - Mus musculus (Mouse)
Length = 1209
Score = 94.3 bits (224), Expect = 2e-17
Identities = 88/336 (26%), Positives = 144/336 (42%), Gaps = 25/336 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGV--RPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSD 338
K + ++ + + A IL+NPG I + T + S KE AF
Sbjct: 623 FVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC- 681
Query: 339 KQAVPNPTIPK--DQTACSFLSNERNPDEGSTSQQK 372
K + T PK + C L +E+ P +Q+
Sbjct: 682 KACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQR 717
>UniRef50_Q86I16 Cluster: Similar to Y51A2D.19.p [Caenorhabditis
elegans]; n=2; Dictyostelium discoideum|Rep: Similar to
Y51A2D.19.p [Caenorhabditis elegans] - Dictyostelium
discoideum (Slime mold)
Length = 1290
Score = 92.7 bits (220), Expect = 5e-17
Identities = 65/211 (30%), Positives = 108/211 (51%), Gaps = 14/211 (6%)
Query: 56 SYSSHRAQSEK-----HVVVCSTTLHADTIMDFLNEFYAHPLLQ-DYYVVLLSPMELDTT 109
SYS ++ K HV++C ++ ++++FL EFY Q +V+LS
Sbjct: 278 SYSPYKRDLSKSNLHGHVILCGD-INFTSLLEFLTEFYLEKYGQLKKTIVILSTNPPSDQ 336
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
++M+L P + R+ Y++GS + + DL RAR + +CFI + D D IL +
Sbjct: 337 LKMLLLHPFYKNRISYLEGSPMLENDLKRARYIHSSSCFIFRPLFWED---GDSTAILTA 393
Query: 170 WAVKDFAPKVAQ-YVQIFRPENKLHVKF-AEFVVCEDEFKYALLANNCTCPGASTLVTLL 227
A+K+ PK ++ +VQ+ ENK + ++++C ++F+ +L + CPG TLV L
Sbjct: 394 LAMKNLKPKGSKIFVQLLHHENKYKISARIKYIMCIEDFRNGILVQSTLCPGFGTLVCNL 453
Query: 228 LHTSRGQEGQQSPEEWHRLYGKCSGNEIYHI 258
TSR Q ++W Y S N IY I
Sbjct: 454 F-TSR-QPDIGDEDKWIGEYCNGSVNSIYKI 482
>UniRef50_Q12791 Cluster: Calcium-activated potassium channel
subunit alpha-1 (Calcium-activated potassium channel,
subfamily M subunit alpha-1) (Maxi K channel) (MaxiK)
(BK channel) (K(VCA)alpha); n=28; Coelomata|Rep:
Calcium-activated potassium channel subunit alpha-1
(Calcium-activated potassium channel, subfamily M
subunit alpha-1) (Maxi K channel) (MaxiK) (BK channel)
(K(VCA)alpha) - Homo sapiens (Human)
Length = 1236
Score = 91.9 bits (218), Expect = 8e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 674
>UniRef50_Q59FH2 Cluster: Large conductance calcium-activated
potassium channel subfamily M alpha member 1 variant;
n=10; Bilateria|Rep: Large conductance calcium-activated
potassium channel subfamily M alpha member 1 variant -
Homo sapiens (Human)
Length = 590
Score = 91.5 bits (217), Expect = 1e-16
Identities = 86/325 (26%), Positives = 140/325 (43%), Gaps = 25/325 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 255 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 310
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 311 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 370
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 371 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 430
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 431 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 483
Query: 282 HRKYGVALVGV--RPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSD 338
K + ++ + + A IL+NPG I + T + S KE AF
Sbjct: 484 FVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC- 542
Query: 339 KQAVPNPTIPK--DQTACSFLSNER 361
K + T PK + C L +E+
Sbjct: 543 KACHDDITDPKRIKKCGCKRLEDEQ 567
>UniRef50_UPI0000E45FEB Cluster: PREDICTED: similar to
calcium-activated potassium channel alpha subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
calcium-activated potassium channel alpha subunit -
Strongylocentrotus purpuratus
Length = 1307
Score = 89.0 bits (211), Expect = 6e-16
Identities = 70/241 (29%), Positives = 110/241 (45%), Gaps = 27/241 (11%)
Query: 49 ERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYV--VLLSPMEL 106
+R K GS S + + KH+VVC + D++ +FL +F H D V ++L
Sbjct: 419 QRGKYSGSLQSEKGK--KHIVVCGHITY-DSVANFLKDFL-HKDRDDVNVEIIILDTAVP 474
Query: 107 DTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTI 166
D ++ + + ++ Y QGS L DL R +M +A+ C +L + D A D I
Sbjct: 475 DLELQALFKRHF--TQLQYFQGSVLNSVDLERVKMKDADGCLVLCDKYCPDPDAEDAANI 532
Query: 167 LRSWAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCP 218
+R +VK++ P + VQ+ + NK H+ + + V+C E K +A +C P
Sbjct: 533 MRVISVKNYHPHIRVIVQLMQYHNKAHLLNIPSWNWREGDDVICIAELKLGFIAQSCLAP 592
Query: 219 GASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYAS 278
G S+++ L R Q W Y + GNE+Y EY KSFT S
Sbjct: 593 GFSSIMANLF-AMRSNSEQVPRGSWQSNYLEGCGNEMY----------TEYLSKSFTGLS 641
Query: 279 F 279
F
Sbjct: 642 F 642
>UniRef50_Q22T07 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1093
Score = 88.2 bits (209), Expect = 1e-15
Identities = 69/281 (24%), Positives = 132/281 (46%), Gaps = 28/281 (9%)
Query: 99 VLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADK 158
V++ M +LQ + ++ Y+ G+ L DL RA++ +A+ ILA + D
Sbjct: 296 VIMKNQHPSEEMLKLLQRNNLSNQLTYLYGNPLNIEDLKRAQVEQAQCVIILADKMTNDH 355
Query: 159 TAADEHTILRSWAVKDFAPKVAQY-----VQIFRPENK------LHVKFAEFVVCEDEFK 207
+ D I+ + AVK + + + +Q+ +P+ K + + + V+C DE K
Sbjct: 356 ESEDHRNIMYTLAVKQYVQNITKSDIRVCLQLLKPQIKDIYYQSIDYGYIDQVICVDELK 415
Query: 208 YALLANNCTCPGASTLVTLLLHTSRGQEG---QQSPEEWHRLYGKCSGNEIYHIVLGDSR 264
LLA C CPG +T+++ L+ + + ++ + W Y + NEIY I L D +
Sbjct: 416 LYLLAKTCLCPGINTIISFLIASDKPDTSVVEKKDEDSWINDYIEGMQNEIYRISL-DPK 474
Query: 265 FFGEYEGKSFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYM 324
F Y +F S H R+ G+ L + E+ E + +NP ++++ + Y+
Sbjct: 475 IFSGY---TFNIVSQHIFRQLGIILFAL---EVKVLDETKLFINPAD-YLIQDIEYYGYV 527
Query: 325 SITKEENSAFV--VSDKQAVPN----PTIPKDQTACSFLSN 359
+++ N+ + V + ++P PT+PK S+L +
Sbjct: 528 IASQQPNNKDIQKVKIESSIPRNHNYPTVPKQMPGTSYLKD 568
Score = 42.3 bits (95), Expect = 0.068
Identities = 29/104 (27%), Positives = 56/104 (53%), Gaps = 12/104 (11%)
Query: 705 ISYMFRLPFAAGSVFSASMLDTLLYQAFVKDYMITFV-RLLLG-------IDQAPGSGFL 756
I Y+ PFA+G ++ ++MLDTL+ QA+ ++I + +L++G + + L
Sbjct: 735 IGYLASEPFASGEIYISTMLDTLICQAYYNPFIINILDQLIMGGATHNPKFKKIYNNLRL 794
Query: 757 ASIKITKEDMWIR----TYGRLYQKLCSTSCEIPIGIYRTQDTS 796
S I D+ ++ T+G+++ S IPIG+Y+ +T+
Sbjct: 795 HSANIFLIDIPLQYESYTFGQIFDVFISVHKMIPIGLYKAANTN 838
>UniRef50_UPI0000F2B976 Cluster: PREDICTED: similar to potassium
channel, subfamily U, member 1; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to potassium channel,
subfamily U, member 1 - Monodelphis domestica
Length = 1015
Score = 84.6 bits (200), Expect = 1e-14
Identities = 75/293 (25%), Positives = 124/293 (42%), Gaps = 21/293 (7%)
Query: 39 FFEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYV 98
+ +L T QK SY R + K +VVC + DT+ FL F H ++
Sbjct: 228 YVPKLVETLTGGQKYAASYKVIRGR--KFIVVCGD-ISVDTVTSFLRNFLGHRSRENNNE 284
Query: 99 VLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADK 158
++ L + I+ ++ + GS LK DL R + +EAC ILA + D
Sbjct: 285 IIFLGESLPSPELEII-FKLYLAYAHFYHGSALKREDLRRVAVESSEACLILANPSCPDS 343
Query: 159 TAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYAL 210
D I+R ++K++ PK +QI +P+NK ++ + ++C E K L
Sbjct: 344 HMEDTANIMRVLSIKNYYPKTRVIIQIIQPQNKDYLLKIPHWNRTSGDNIICFAELKLGL 403
Query: 211 LANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYE 270
+A C PG +T + L G+ + P W L N+I+ L ++E
Sbjct: 404 IAQGCLVPGLATFLISLFMEQTGKAIPKHP--WQELLVDGLSNKIFTHFLS-----CDFE 456
Query: 271 GKSFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYY 323
G SF S K + L+ + + +++LNP P I + +T Y
Sbjct: 457 GMSFREVSRLCFVKLRLMLIAIEYKTKENGFR-SLMLNP-PEMIKVNRNTIGY 507
>UniRef50_Q54SN1 Cluster: Ca-activated BK potassium channel, alpha
subunit family protein; n=2; Dictyostelium
discoideum|Rep: Ca-activated BK potassium channel, alpha
subunit family protein - Dictyostelium discoideum AX4
Length = 977
Score = 79.8 bits (188), Expect = 4e-13
Identities = 58/193 (30%), Positives = 100/193 (51%), Gaps = 7/193 (3%)
Query: 67 HVVVCSTTLHADTIMDFLNEFYAHPLLQ-DYYVVLLSPMELDTTMRMILQVPIWAQRVIY 125
HV++C + ++DFL+EFY + +V+LSP D ++ +L P + R+IY
Sbjct: 118 HVILCGD-ITISHLLDFLSEFYHERYGKLKKELVILSPKAPDDRIKALLLHPFYKNRLIY 176
Query: 126 IQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQYVQI 185
++GS L + DL R ++++A++ FI ++ +AD IL S+AVK + + +
Sbjct: 177 LKGSPLFEHDLQRTKISKADSVFITLPSSW---NSADTDNILCSYAVKSQYKNLKIFSHL 233
Query: 186 FRPENKLHVKFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHR 245
+NK F + + +EF+ A+LA + CPG + L + L TSR S +W
Sbjct: 234 ISSKNKNKSPFLKGSIYVEEFRCAMLAQSIVCPGYNILFSNLF-TSRTIPTMVS-HKWLT 291
Query: 246 LYGKCSGNEIYHI 258
Y + + IY I
Sbjct: 292 EYYYGTNHSIYII 304
>UniRef50_Q03720-16 Cluster: Isoform L of Q03720 ; n=29;
Neoptera|Rep: Isoform L of Q03720 - Drosophila
melanogaster (Fruit fly)
Length = 1187
Score = 77.8 bits (183), Expect = 1e-12
Identities = 69/292 (23%), Positives = 123/292 (42%), Gaps = 20/292 (6%)
Query: 52 KLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQ-DYYVVLLSPMELDTTM 110
K GG R ++H+VVC + +++ FL +F D VV L D +
Sbjct: 345 KYGGELK--REHGKRHIVVCGHITY-ESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLEL 401
Query: 111 RMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSW 170
+ + V + QG+ + DL R +++EA+AC +LA + D A D I+R
Sbjct: 402 EGLFKRHFTT--VEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVI 459
Query: 171 AVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAST 222
++K+++ + +Q+ + NK ++ K + V+C E K +A +C PG ST
Sbjct: 460 SIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFST 519
Query: 223 LVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSH 282
++ L R + + W Y + +G E+Y L + + G F A+
Sbjct: 520 MMANLF-AMRSFKTSPDMQSWTNDYLRGTGMEMYTETLSPT-----FIGIPFAQATELCF 573
Query: 283 RKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAF 334
K + L+ + E + I +NP I +T + E A+
Sbjct: 574 SKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFFIAQSADEVKRAW 625
>UniRef50_Q03720 Cluster: Calcium-activated potassium channel
slowpoke; n=10; Coelomata|Rep: Calcium-activated
potassium channel slowpoke - Drosophila melanogaster
(Fruit fly)
Length = 1200
Score = 77.8 bits (183), Expect = 1e-12
Identities = 69/292 (23%), Positives = 123/292 (42%), Gaps = 20/292 (6%)
Query: 52 KLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQ-DYYVVLLSPMELDTTM 110
K GG R ++H+VVC + +++ FL +F D VV L D +
Sbjct: 345 KYGGELK--REHGKRHIVVCGHITY-ESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLEL 401
Query: 111 RMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSW 170
+ + V + QG+ + DL R +++EA+AC +LA + D A D I+R
Sbjct: 402 EGLFKRHFTT--VEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVI 459
Query: 171 AVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAST 222
++K+++ + +Q+ + NK ++ K + V+C E K +A +C PG ST
Sbjct: 460 SIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFST 519
Query: 223 LVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSH 282
++ L R + + W Y + +G E+Y L + + G F A+
Sbjct: 520 MMANLF-AMRSFKTSPDMQSWTNDYLRGTGMEMYTETLSPT-----FIGIPFAQATELCF 573
Query: 283 RKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAF 334
K + L+ + E + I +NP I +T + E A+
Sbjct: 574 SKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFFIAQSADEVKRAW 625
>UniRef50_Q22T08 Cluster: High conductance calcium-activated
potassium channel protein; n=1; Tetrahymena thermophila
SB210|Rep: High conductance calcium-activated potassium
channel protein - Tetrahymena thermophila SB210
Length = 987
Score = 75.4 bits (177), Expect = 8e-12
Identities = 57/218 (26%), Positives = 101/218 (46%), Gaps = 18/218 (8%)
Query: 66 KHVVVCSTTLHADTIMDFLNEFYA--HPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRV 123
+H+++ L + FL+E Y H ++Q + V++ M +LQ + +
Sbjct: 213 EHILILGNAL-VEGYKTFLSELYHQDHGIVQ-FPSVIMKNQHPSEDMLKLLQKNSFQTNL 270
Query: 124 IYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQY- 182
Y+ G+ L + DL RA+ A+ ILA + +D D I+ + AVK + A+
Sbjct: 271 TYLFGNPLSNNDLKRAQAENAQCVVILADKMTSDPQQEDHRNIMYTLAVKQYVYNTAKTD 330
Query: 183 ----VQIFRPENK-LHVKFAEF-----VVCEDEFKYALLANNCTCPGASTLVTLLLHTSR 232
+Q+ PE K ++ + ++ V+C DE K LLA C CPG +T+++ L+ + +
Sbjct: 331 IRVCLQLLNPELKDIYFESLDYGQIDQVICVDELKLYLLAKTCQCPGINTIISFLITSDK 390
Query: 233 GQEG---QQSPEEWHRLYGKCSGNEIYHIVLGDSRFFG 267
++ + W Y NEIY + L F G
Sbjct: 391 PDVSVVDKRDEDSWINDYIMGMQNEIYRVHLDQQNFSG 428
Score = 37.5 bits (83), Expect = 1.9
Identities = 16/43 (37%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 705 ISYMFRLPFAAGSVFSASMLDTLLYQAFVKDYMITFV-RLLLG 746
I Y+ PFA+G ++ ++MLDTL+ QA+ ++I + +L++G
Sbjct: 730 IGYIASEPFASGEIYISTMLDTLICQAYYNPFIINILDQLIMG 772
Score = 35.5 bits (78), Expect = 7.8
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Query: 612 NGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGT 662
+G+ + ++PLRA RS T+NPII+L + I+ FP VY++ G+
Sbjct: 603 SGMKHLLMPLRA--RSLKTINPIIILNNETMPSELWNQINSFPKVYFLQGS 651
>UniRef50_Q38F65 Cluster: Calcium/potassium channel (CAKC),
putative; n=3; Trypanosoma|Rep: Calcium/potassium
channel (CAKC), putative - Trypanosoma brucei
Length = 878
Score = 66.9 bits (156), Expect = 3e-09
Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 2/134 (1%)
Query: 98 VVLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYAD 157
VVLLSP++ +R++ +P RV+ + G K DLIRA AEA F+ A
Sbjct: 302 VVLLSPVDFPPEVRLLADIPWLRNRVVLMIGDSAKQVDLIRADAANAEAIFLFGDTGSA- 360
Query: 158 KTAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHV-KFAEFVVCEDEFKYALLANNCT 216
AD I +S A++ F P++ Q++ + + HV +A VV + + LL
Sbjct: 361 AYHADYQVIQQSLAIRQFDPELPQHLYLRSERHTRHVASYAASVVEVERLLHHLLGLGAA 420
Query: 217 CPGASTLVTLLLHT 230
PGA L+ LL T
Sbjct: 421 VPGAVPLIMNLLRT 434
>UniRef50_O54982 Cluster: PH sensitive maxi K+ channel; n=13;
Eutheria|Rep: PH sensitive maxi K+ channel - Mus
musculus (Mouse)
Length = 1121
Score = 64.9 bits (151), Expect = 1e-08
Identities = 68/306 (22%), Positives = 127/306 (41%), Gaps = 23/306 (7%)
Query: 39 FFEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYV 98
+ ++ + R+K Y + + +K +VVC + D++ FL F H + +
Sbjct: 307 YIPEMVELFSTRKKYTKPYEA--VKGKKFIVVCGN-ITVDSVTAFLRNFL-HWKSGEINI 362
Query: 99 VLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADK 158
++ E + + + ++ G+ LK DL R + +EAC ILA +D
Sbjct: 363 EIVFLGETLPCLELETLLKCHTSCTNFVCGTALKFEDLKRVAVENSEACLILANHFCSDL 422
Query: 159 TAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYAL 210
D I+R ++K++ P+ +QI + +NK+ + + ++C E K
Sbjct: 423 HDEDNSNIMRVLSIKNYYPQTRVIIQILQSQNKVFLSKIPNWDWSAGDNILCFAELKLGF 482
Query: 211 LANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYE 270
+A C PG T +T L + + P + H L G N+I R ++
Sbjct: 483 IAQGCLVPGLCTFLTTLFIEQNQKVFPKHPWQKHFLNG--LKNKIL-----TQRLSNDFV 535
Query: 271 GKSFTYASFHSHRKYGVALVGVRPAELPEFYE-DTILLNPGPR-HIMKSTDTCYYMSITK 328
G +F S K + L+ ++ P F+ T++LNP + + K T + +K
Sbjct: 536 GMTFPQVSRLCFVKLNLMLIAIQ--HKPFFHSCCTLILNPSSQVRLNKDTLGFFIADSSK 593
Query: 329 EENSAF 334
AF
Sbjct: 594 AVKRAF 599
>UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Acetyl-CoA acyltransferases family protein - Tetrahymena
thermophila SB210
Length = 1352
Score = 61.7 bits (143), Expect = 1e-07
Identities = 66/269 (24%), Positives = 113/269 (42%), Gaps = 45/269 (16%)
Query: 58 SSHRAQSE-KHVVVCSTTLHADTIMDFLNEFYAHPLL--QDYYVVLLSPMELDTTMRMIL 114
+ +R+ E H++VC + + F E + HP QD + ++L + L
Sbjct: 272 NKYRSNPEIPHILVCGH-VELSALKFFCKELF-HPDHGGQDKHAIILQHNPPSQEIEQFL 329
Query: 115 QVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKD 174
P + + Y+QG+ + D DL R + ++AC +L + D +AD +L A+K
Sbjct: 330 HNPQFELFLHYLQGNPMLDRDLRRTSVYSSKACVLLTDKYITDSHSADHKNVLTGLAIKK 389
Query: 175 FAP-------KVAQYVQIFRPENKLHV------KFAEFVVCEDEFKYALLANNCTCPGAS 221
F + +Q+ +PE+K H K + ++ +EFK L A
Sbjct: 390 FVHHQTKGENSIRLCIQLIKPESKAHYYSSLSFKSNDLLIVVEEFKMNLSAGEI------ 443
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
+ Q +EW + Y G+EIY L ++EGK+FT +
Sbjct: 444 -------------DDSQYEDEWLKEYMTGIGHEIYRAALSS-----KFEGKTFTEIAATV 485
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPG 310
+ ++G L G+ EL + I LNPG
Sbjct: 486 YNEFGGILFGI---ELDVGGQTIIRLNPG 511
Score = 35.9 bits (79), Expect = 5.9
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
Query: 67 HVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVIYI 126
H+V+C +H+ +I F+ A L + Y+V+L + I + P ++I+I
Sbjct: 626 HIVLCG--IHS-SIYYFILPLRAKYLKEFQYIVILCEEQPTKIWNDINRFP----KIIFI 678
Query: 127 QGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQYVQI 185
+GS LK DL+RA + A+ I + + DE S + K+ + VQI
Sbjct: 679 KGSPLKHEDLMRANIQFADKAVIFSKEVTKEMNQVDEMLDSESIFIYKAIQKLNKNVQI 737
>UniRef50_Q55CU6 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1244
Score = 58.4 bits (135), Expect = 1e-06
Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 4/173 (2%)
Query: 60 HRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIW 119
++ +K V + ++ FL EF+ + + + V++LS ++ + +
Sbjct: 404 YKPSKKKKFVTIIGNIFESSLTTFLREFFFNSRIGEMPVIILSNVDQPSFWDSLTNRI-- 461
Query: 120 AQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKV 179
+R + +GS D+ R +++ ++A FI + ++ D ILR +V+ F +
Sbjct: 462 KKRYFFFKGSIGSQQDVQRVKLDRSKAVFIFSKKSLNHSQQDDNENILRVMSVRSFNATI 521
Query: 180 AQYVQIFRP--ENKLHVKFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHT 230
+ Q P + K+ A VV E K LLA +C PG TLV LL +
Sbjct: 522 PIFAQAMVPRLKRKMIAAGATQVVSVQELKMNLLAQSCISPGFITLVMNLLRS 574
Score = 37.9 bits (84), Expect = 1.5
Identities = 25/85 (29%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 713 FAAGSVFSASMLDTLLYQAFVKDYMITFVRLLLGIDQAPGSGFLASI-KITK----EDMW 767
FAAG+VF +S+ D+LL Q F ++++ + +L+G++ + F S+ K+ + E +
Sbjct: 1046 FAAGNVFLSSVFDSLLCQCFFNPHLLSMISVLVGMN--TDNQFKKSVTKVFQVPLPEHFY 1103
Query: 768 IRTYGRLYQKLCSTSCEIPIGIYRT 792
+G L++ L ++ I I ++RT
Sbjct: 1104 HHRFGYLFESLVESNI-ICIALFRT 1127
>UniRef50_A0CYF6 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 995
Score = 57.6 bits (133), Expect = 2e-06
Identities = 47/183 (25%), Positives = 84/183 (45%), Gaps = 24/183 (13%)
Query: 63 QSEKHVVVCSTTLHADTIMDFLNEFY-AHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQ 121
+ +H+++ ++ + FLNE Y + D V+L P M + L+ P
Sbjct: 263 KESEHLLLLGSS-QVEGFKTFLNELYHTDHGMNDINTVILQPSAPTEEMTLQLKQPALQS 321
Query: 122 RVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQ 181
+VIY++G L++ DL R + ++ + + I+ ++AVK FA K
Sbjct: 322 KVIYLEGHPLQNKDLERCSSKDCN-------QHLREMITVN---IIHAFAVKQFAKKQKS 371
Query: 182 Y------VQIFRPENK------LHVKFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLH 229
+Q+ +P +K L + V+C DE K LL C CPG +TL++ L+
Sbjct: 372 RKGARVCLQVLQPSSKDLYFNSLGGHETDQVICVDELKLYLLGKTCLCPGINTLISFLIQ 431
Query: 230 TSR 232
+S+
Sbjct: 432 SSK 434
Score = 42.3 bits (95), Expect = 0.068
Identities = 27/93 (29%), Positives = 56/93 (60%), Gaps = 14/93 (15%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMIT-FVRLLLG---IDQAPGSGFLASIKITKEDMW 767
PFA+G ++ ++MLDTL+ QAF ++ + F +++LG +++ + A+ K+ + +++
Sbjct: 751 PFASGEIYISTMLDTLICQAFYNPFITSIFDQMILGSASVNKKHKKLYQAN-KLQQSNLF 809
Query: 768 I---------RTYGRLYQKLCSTSCEIPIGIYR 791
+ +T+G L++ L + IPIG+YR
Sbjct: 810 LINIPPKYQEKTFGELFEILLTEQKMIPIGLYR 842
>UniRef50_Q6L2S2 Cluster: Potassium channel protein; n=1;
Picrophilus torridus|Rep: Potassium channel protein -
Picrophilus torridus
Length = 322
Score = 48.4 bits (110), Expect = 0.001
Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 125 YIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQYVQ 184
Y++G +K+ DLI+A + +A + A + D A D TIL + +K V +
Sbjct: 161 YVKGMAIKERDLIKAGIKKALTVIVFAKNDDRDSLAIDAETILSAMVIKKLNKNVHVIAE 220
Query: 185 IFRPENKLHVK-FAEFVVCEDEFKYALLANNCTCPGASTLVTLL 227
+ P+++ H F + + + L+A + PG + L + +
Sbjct: 221 LLNPDSREHASAFVDETIVHGDVTAELIAASIMNPGITNLFSTI 264
>UniRef50_A4HRK5 Cluster: Potassium channel subunit-like protein;
n=2; Leishmania|Rep: Potassium channel subunit-like
protein - Leishmania infantum
Length = 1294
Score = 42.3 bits (95), Expect = 0.068
Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 2/163 (1%)
Query: 67 HVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVIYI 126
HVV+C + + M N F + VVLL + + ++L P + V +
Sbjct: 503 HVVICGHLGYNELRMQLKNVFAEDRHYLNMSVVLLLREQPSAQVLLLLNSPKYRSAVHLL 562
Query: 127 QGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQYVQIF 186
G TDL R A A F+L A + +D ++ V P + Y+ +
Sbjct: 563 VGDPGVPTDLDRCNARGASAMFLLGAGTNS-SYYSDYDLAAQTMTVNALVPDLPLYILLH 621
Query: 187 RPENKLHVKFAEFVVCE-DEFKYALLANNCTCPGASTLVTLLL 228
R + + +V E + + LL C PG LV L+
Sbjct: 622 RSRYTKSLMPSRAIVLEFERLNHNLLGLGCVLPGIIPLVANLM 664
>UniRef50_A7AT63 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 710
Score = 41.9 bits (94), Expect = 0.089
Identities = 55/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 140 RMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPK----VAQYVQIFRPENKLHVK 195
+ +A F+L++ + D AD T+ R ++K F + QY RP+ H
Sbjct: 176 KAKDAVGTFVLSSFKHGDPRKADMKTVGRVISLKKFGISADRVIIQYCSTLRPQIA-HRP 234
Query: 196 FAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEI 255
+ VV FK A++A N TCPG TL+ L T + ++ + Y + G +
Sbjct: 235 YTN-VVNLYRFKSAIIAKNITCPGIITLIINLSLTHSAIVQRCKGDDLYDNYVRGIGRRL 293
Query: 256 YHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNP-GPRHI 314
I + + G F + + +G ++G+ Y T LNP G ++
Sbjct: 294 RTIAISE-----RLVGTDFDTLCSNLYNIHGYIVIGIIHGN--HNYR-TYQLNPSGSGYM 345
Query: 315 MKSTDTCYYMSITKEENSAFVVSD-KQAVPNPTIPKDQTACSFLSNERNPDEGSTSQQKK 373
++ D + + E+S+ D + N T+P + S + N D ++ +
Sbjct: 346 IRPGDRA--VLVADVESSSKTKHDIVTSGRNSTVPIRSSMISLVLNRIGSDITASLDEMD 403
Query: 374 PDGS 377
DG+
Sbjct: 404 NDGN 407
>UniRef50_Q9K7M1 Cluster: Potassium channel protein; n=1; Bacillus
halodurans|Rep: Potassium channel protein - Bacillus
halodurans
Length = 338
Score = 39.5 bits (88), Expect = 0.48
Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 115 QVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKD 174
++P +RV +++G+ +D L +A + EA A ++ A++ + +AD +IL + AVK
Sbjct: 152 ELPSTYRRVHFVRGNSTEDAILQQANVREA-ASVLITAKHQGSEFSADSRSILTTLAVKS 210
Query: 175 FAPKVAQYVQI 185
P V V+I
Sbjct: 211 INPHVYTVVEI 221
>UniRef50_Q4D359 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 1863
Score = 39.1 bits (87), Expect = 0.63
Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 9/147 (6%)
Query: 46 TWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNE--FYAHPLLQDYYVVLLSP 103
T+ R+ GS+ K V+ + T+H + FL+E F+ L+Q V+L P
Sbjct: 771 TFQARENGSGSFDKEEHDDHKSGVIINRTVHRFLMTFFLSEGGFFPRELVQHRIVLLSHP 830
Query: 104 MELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEA-EACFILA-ARNYADKTAA 161
L + + + + VP +QGS + D N + E F L R+
Sbjct: 831 SRLSSIINVQMLVP-----PSKMQGSSAETLDEEEPSWNNSREGLFPLTPMRHLNPPVEC 885
Query: 162 DEHTILRSWAVKDFAPKVAQYVQIFRP 188
DE L SW+ K P ++ + P
Sbjct: 886 DEEFPLLSWSGKGPTPTLSMLQGLMHP 912
>UniRef50_UPI00006CC471 Cluster: cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: cation channel family
protein - Tetrahymena thermophila SB210
Length = 1709
Score = 38.3 bits (85), Expect = 1.1
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 141 MNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKF---A 197
+++ CF + + T D +L + + D P+ + Q+ EN L F
Sbjct: 369 LSKKAICFQQNQQFSIENTKEDSFALLATQVISDLYPRCQIFTQVNSKEN-LFWNFWHGQ 427
Query: 198 EFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYH 257
+ + + + N PG ST+++ L + Q+ SP W + + NEIY
Sbjct: 428 KSLTSSNLLTMGTITQNVFIPGFSTMISNLSMSLSEQD--YSP--WKLEFIEGMSNEIYI 483
Query: 258 IVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVR 293
+ + Y GKSF A + K G+ ++G++
Sbjct: 484 FDFKEDKN-NCYVGKSFQQACLEIYNKTGILMIGLK 518
>UniRef50_Q929U4 Cluster: Lin2180 protein; n=13; Listeria|Rep:
Lin2180 protein - Listeria innocua
Length = 319
Score = 38.3 bits (85), Expect = 1.1
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 210 LLANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEY 269
L+AN P S +L H RG+ G+ R+Y + G Y++++ D+R GE
Sbjct: 84 LVANYLEAPSPSNTTIILAHGYRGKSGKVEMAGLARMYNQKFG---YNVLMPDARAHGES 140
Query: 270 EGKSFTY 276
EGK+ +
Sbjct: 141 EGKNIGF 147
>UniRef50_A0WA57 Cluster: Ion transport 2; n=1; Geobacter lovleyi
SZ|Rep: Ion transport 2 - Geobacter lovleyi SZ
Length = 347
Score = 38.3 bits (85), Expect = 1.1
Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 114 LQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVK 173
L V + + V Y++G+ +D L RA +++A IL R+ D A+D + + A++
Sbjct: 163 LPVELQKRGVHYVRGNPTRDETLQRAAIDQARHAVILT-RDPTDP-ASDNLNVAIALAIE 220
Query: 174 DFAPKVAQYVQIFRP--ENKLHVKFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTS 231
+V V+ P E L + +VC F L+ PG ++ LL
Sbjct: 221 GRCKQVNTVVECIDPASEELLRKAGCDRIVCTSRFDAHFLSQELLNPGVQEVLGDLLSNG 280
Query: 232 RGQE 235
+GQ+
Sbjct: 281 QGQQ 284
>UniRef50_A0BDF5 Cluster: Chromosome undetermined scaffold_100,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_100,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 566
Score = 37.9 bits (84), Expect = 1.5
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 11/110 (10%)
Query: 859 LVRSRMESLNLTGVDYDDVSE--KRNSLSYVII----NPSCDLNLQEGD-IMNLVIDADT 911
L+ R+ +N+ +D ++ + K N L + N D + D I N I+ D
Sbjct: 455 LIDYRIWDINIEKLDIQELKQMQKSNDLQTEFLEVKQNKYDDATIDRKDEIGNTFIEIDG 514
Query: 912 TGKFS---DIVPLMVYKLEILNHYELASPTI-ITDFRGRSNSLRVVDDIL 957
+ F D+V VYK +ILN Y++ +I + + RG SNSL+ + DI+
Sbjct: 515 SCHFDIRLDVVTQTVYKKKILNKYQINLKSIPLNENRGISNSLQAILDII 564
>UniRef50_Q5KVS9 Cluster: Potassium channel protein; n=2;
Geobacillus|Rep: Potassium channel protein - Geobacillus
kaustophilus
Length = 529
Score = 37.1 bits (82), Expect = 2.5
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 99 VLLSPMELDTTMRMIL------QVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAA 152
VLL D +MR +L P+ V +I+G+ D L +A + EA I A
Sbjct: 327 VLLRLARHDASMRFVLIDATVPSHPLLNAPVHFIKGTASDDAVLEKANIQEARFLLITAD 386
Query: 153 RNYADKTAADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHV--KFAEFVVCEDEFKYAL 210
+ A+ AD+ TI+ A K P V V+I N + A+ V+ +
Sbjct: 387 PHKAE-AEADKDTIVTLLAAKSLNPSVYAIVEILTGRNVQNAFRAGADEVIQTNLLASFA 445
Query: 211 LANNCTCPGASTLVTLLLHTSRGQ 234
LA + PGA+++ L+ GQ
Sbjct: 446 LAASLRSPGAASVWETALYRLDGQ 469
>UniRef50_Q9BJ49 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 1110
Score = 36.3 bits (80), Expect = 4.4
Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 2/127 (1%)
Query: 117 PIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFA 176
P + R ++ L L R + EA A I R + D+ +L + + F
Sbjct: 399 PTYRLRSTFLIVDTLDTFALRRMKAQEASAVIIFPIRE-GYSSRVDDDVMLAAIIFERFV 457
Query: 177 PKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEG 236
PKV QYV + + +K V ++ K ++A+ PG + L+ T+ EG
Sbjct: 458 PKVPQYVWLRYGLHAKLLKGQRSCVIDEHMKKNIMASALLLPGIVPFLVNLVRTA-WAEG 516
Query: 237 QQSPEEW 243
++ + W
Sbjct: 517 EEPADLW 523
>UniRef50_Q3ADY6 Cluster: Formate dehydrogenase-O, iron-sulfur
subunit; n=1; Carboxydothermus hydrogenoformans
Z-2901|Rep: Formate dehydrogenase-O, iron-sulfur subunit
- Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
6008)
Length = 260
Score = 35.9 bits (79), Expect = 5.9
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 14/122 (11%)
Query: 762 TKEDMWIRTYGRLYQ-KLCSTSCEIPIGIYRTQDTSMADASHHQEELDGGDFPACGRQEA 820
TKE +R Y R C +C I TQ+ M + + L+ G+ PAC A
Sbjct: 92 TKEGAVVRDYDRCIGCDYCQRACPFNIPRIDTQNKKMHKCTLCFDRLENGEIPAC----A 147
Query: 821 TSCLGGC--YGERTPVYSTSLADEARDNHIQQIERA-EIANLVRSRMESLNLTGVDYDDV 877
+C G YG R ++ EA + ++++ ANL S +L TGV Y +
Sbjct: 148 LTCSPGAIKYGNRDELW------EAAQKRLAEVKKEYPKANLYPSDKNALGGTGVFYLLI 201
Query: 878 SE 879
+E
Sbjct: 202 NE 203
>UniRef50_O67715 Cluster: Potassium channel protein; n=1; Aquifex
aeolicus|Rep: Potassium channel protein - Aquifex
aeolicus
Length = 455
Score = 35.5 bits (78), Expect = 7.8
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 15/153 (9%)
Query: 65 EKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTTMRMILQVPIWAQRVI 124
+ H+VVC + +++ + +++ + +V+++ EL+T
Sbjct: 239 KNHIVVCGWNETGEVMLEEIMKYWEEKGERKKPIVVVTDQELETR-----------HEFY 287
Query: 125 YIQGSCLKDTDLIRARMNEAEACFILAARNY-ADKTAADEHTILRSWAVKDFAPKVAQYV 183
Y +G + + L A + A+ ILA + + + D TIL S +D PK
Sbjct: 288 YKKGDYVSEEVLKNAGVEHADMIIILAEKGVDLTEDSIDARTILSSMLARDLNPKATIIA 347
Query: 184 QIFRPENKLHVK---FAEFVVCEDEFKYALLAN 213
+I EN VK ++++ + E +++N
Sbjct: 348 EILLRENAKTVKRKNIIDYIIVDGEVVGQMISN 380
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.134 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,133,766,087
Number of Sequences: 1657284
Number of extensions: 46361101
Number of successful extensions: 98213
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 97999
Number of HSP's gapped (non-prelim): 164
length of query: 1061
length of database: 575,637,011
effective HSP length: 108
effective length of query: 953
effective length of database: 396,650,339
effective search space: 378007773067
effective search space used: 378007773067
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 78 (35.5 bits)
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