Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000705-TA|BGIBMGA000705-PA|IPR003929|Calcium-activated
BK potassium channel, alpha subunit
(1061 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC103950-1|AAI03951.1| 1111|Homo sapiens KCNT2 protein protein. 459 e-128
BC103948-1|AAI03949.1| 1111|Homo sapiens KCNT2 protein protein. 459 e-128
AY359444-1|AAR06170.1| 1135|Homo sapiens sodium- and chloride-ac... 459 e-128
AL591604-2|CAH72932.1| 1111|Homo sapiens potassium channel, subf... 459 e-128
AL591604-1|CAH72933.1| 1135|Homo sapiens potassium channel, subf... 459 e-128
AL358853-2|CAH71957.1| 1135|Homo sapiens potassium channel, subf... 459 e-128
AL358853-1|CAH71958.1| 1111|Homo sapiens potassium channel, subf... 459 e-128
AL139137-2|CAI16092.1| 1111|Homo sapiens potassium channel, subf... 459 e-128
AL139137-1|CAI16091.1| 1135|Homo sapiens potassium channel, subf... 459 e-128
AL138931-2|CAI15623.1| 1135|Homo sapiens potassium channel, subf... 459 e-128
AL138931-1|CAI15624.1| 1111|Homo sapiens potassium channel, subf... 459 e-128
AK127807-1|BAC87144.1| 523|Homo sapiens protein ( Homo sapiens ... 459 e-128
AL158822-4|CAI39240.1| 1315|Homo sapiens potassium channel, subf... 456 e-127
AB037843-1|BAA92660.1| 1151|Homo sapiens KIAA1422 protein protein. 456 e-127
AK131498-1|BAD18642.1| 1052|Homo sapiens protein ( Homo sapiens ... 450 e-125
BC103949-1|AAI03950.1| 1068|Homo sapiens KCNT2 protein protein. 304 9e-82
BC103947-1|AAI03948.1| 370|Homo sapiens KCNT2 protein protein. 277 2e-73
U23767-1|AAA92290.1| 1178|Homo sapiens calcium-activated potassi... 93 5e-18
U13913-1|AAA85104.1| 1178|Homo sapiens large-conductance calcium... 93 5e-18
U11717-1|AAC50353.1| 1154|Homo sapiens calcium activated potassi... 93 5e-18
U11058-1|AAB65837.1| 1113|Homo sapiens large conductance calcium... 93 5e-18
AY040849-1|AAK91504.1| 1154|Homo sapiens large conductance calci... 93 5e-18
AL731560-9|CAI40877.1| 1178|Homo sapiens potassium large conduct... 93 5e-18
AL731560-8|CAI40872.1| 1166|Homo sapiens potassium large conduct... 93 5e-18
AL731560-7|CAI40874.1| 1205|Homo sapiens potassium large conduct... 93 5e-18
AL731560-6|CAI40875.1| 1181|Homo sapiens potassium large conduct... 93 5e-18
AL731560-3|CAI40868.1| 1167|Homo sapiens potassium large conduct... 93 5e-18
AL731560-2|CAI40870.1| 1177|Homo sapiens potassium large conduct... 93 5e-18
AL731556-10|CAI14082.1| 1178|Homo sapiens potassium large conduc... 93 5e-18
AL731556-7|CAI14077.1| 1166|Homo sapiens potassium large conduct... 93 5e-18
AL731556-6|CAI14076.1| 1181|Homo sapiens potassium large conduct... 93 5e-18
AL731556-5|CAI14079.1| 1205|Homo sapiens potassium large conduct... 93 5e-18
AL731556-4|CAI14074.1| 1177|Homo sapiens potassium large conduct... 93 5e-18
AL731556-1|CAI14073.1| 1167|Homo sapiens potassium large conduct... 93 5e-18
AL627447-10|CAI16171.1| 1178|Homo sapiens potassium large conduc... 93 5e-18
AL627447-8|CAI16169.1| 1181|Homo sapiens potassium large conduct... 93 5e-18
AL627447-7|CAI16166.1| 1205|Homo sapiens potassium large conduct... 93 5e-18
AL627447-6|CAI16168.1| 1166|Homo sapiens potassium large conduct... 93 5e-18
AL627447-2|CAI16162.1| 1177|Homo sapiens potassium large conduct... 93 5e-18
AL627447-1|CAI16163.1| 1167|Homo sapiens potassium large conduct... 93 5e-18
AL157833-9|CAI39736.1| 1178|Homo sapiens potassium large conduct... 93 5e-18
AL157833-8|CAI39735.1| 1181|Homo sapiens potassium large conduct... 93 5e-18
AL157833-7|CAI39734.1| 1205|Homo sapiens potassium large conduct... 93 5e-18
AL157833-6|CAI39732.1| 1166|Homo sapiens potassium large conduct... 93 5e-18
AL157833-4|CAI39728.1| 1167|Homo sapiens potassium large conduct... 93 5e-18
AL157833-3|CAI39730.1| 1177|Homo sapiens potassium large conduct... 93 5e-18
AF025999-1|AAB88802.1| 1154|Homo sapiens calcium-activated potas... 93 5e-18
AB113575-1|BAD06397.1| 1195|Homo sapiens BK variant stretch-acti... 93 5e-18
AF118141-1|AAD31173.1| 1113|Homo sapiens BKCA alpha subunit prot... 93 6e-18
U02632-1|AAA50173.1| 885|Homo sapiens calcium-activated potassi... 92 1e-17
AL731560-13|CAI40881.1| 885|Homo sapiens potassium large conduc... 92 1e-17
AL731560-10|CAI40878.1| 1210|Homo sapiens potassium large conduc... 92 1e-17
AL731560-5|CAI40873.1| 1171|Homo sapiens potassium large conduct... 92 1e-17
AL731560-4|CAI40871.1| 1209|Homo sapiens potassium large conduct... 92 1e-17
AL731560-1|CAI40869.1| 1225|Homo sapiens potassium large conduct... 92 1e-17
AL731556-9|CAI14081.1| 1210|Homo sapiens potassium large conduct... 92 1e-17
AL731556-8|CAI14078.1| 1171|Homo sapiens potassium large conduct... 92 1e-17
AL731556-3|CAI14075.1| 1225|Homo sapiens potassium large conduct... 92 1e-17
AL731556-2|CAI14072.1| 1209|Homo sapiens potassium large conduct... 92 1e-17
AL627447-9|CAI16172.1| 1210|Homo sapiens potassium large conduct... 92 1e-17
AL627447-5|CAI16170.1| 1171|Homo sapiens potassium large conduct... 92 1e-17
AL627447-4|CAI16164.1| 1209|Homo sapiens potassium large conduct... 92 1e-17
AL627447-3|CAI16165.1| 1225|Homo sapiens potassium large conduct... 92 1e-17
AL157833-11|CAI39738.1| 885|Homo sapiens potassium large conduc... 92 1e-17
AL157833-10|CAI39737.1| 1210|Homo sapiens potassium large conduc... 92 1e-17
AL157833-5|CAI39733.1| 1171|Homo sapiens potassium large conduct... 92 1e-17
AL157833-2|CAI39729.1| 1225|Homo sapiens potassium large conduct... 92 1e-17
AL157833-1|CAI39731.1| 1209|Homo sapiens potassium large conduct... 92 1e-17
AB113382-1|BAD06365.1| 1212|Homo sapiens stretch-activated Kca c... 92 1e-17
AB209488-1|BAD92725.1| 590|Homo sapiens large conductance calci... 91 1e-17
U09384-1|AAA50216.1| 609|Homo sapiens calcium-activated potassi... 88 1e-16
AL731560-11|CAI40879.1| 263|Homo sapiens potassium large conduc... 39 0.082
AY445624-1|AAS01054.1| 157|Homo sapiens potassium large conduct... 35 1.8
>BC103950-1|AAI03951.1| 1111|Homo sapiens KCNT2 protein protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>BC103948-1|AAI03949.1| 1111|Homo sapiens KCNT2 protein protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>AY359444-1|AAR06170.1| 1135|Homo sapiens sodium- and
chloride-activated ATP-sensitive potassium channel
protein.
Length = 1135
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 836 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 895
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 896 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 955
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 956 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 1015
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 1016 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1073
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1074 NDHQSTLSYILINPSPDTRIELNDVVYLI 1102
Score = 158 bits (383), Expect = 1e-37
Identities = 68/114 (59%), Positives = 90/114 (78%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 782
>AL591604-2|CAH72932.1| 1111|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>AL591604-1|CAH72933.1| 1135|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1135
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 836 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 895
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 896 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 955
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 956 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 1015
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 1016 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1073
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1074 NDHQSTLSYILINPSPDTRIELNDVVYLI 1102
Score = 158 bits (383), Expect = 1e-37
Identities = 68/114 (59%), Positives = 90/114 (78%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 782
>AL358853-2|CAH71957.1| 1135|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1135
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 836 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 895
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 896 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 955
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 956 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 1015
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 1016 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1073
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1074 NDHQSTLSYILINPSPDTRIELNDVVYLI 1102
Score = 158 bits (383), Expect = 1e-37
Identities = 68/114 (59%), Positives = 90/114 (78%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 782
>AL358853-1|CAH71958.1| 1111|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>AL139137-2|CAI16092.1| 1111|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>AL139137-1|CAI16091.1| 1135|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1135
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 836 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 895
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 896 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 955
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 956 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 1015
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 1016 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1073
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1074 NDHQSTLSYILINPSPDTRIELNDVVYLI 1102
Score = 158 bits (383), Expect = 1e-37
Identities = 68/114 (59%), Positives = 90/114 (78%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 782
>AL138931-2|CAI15623.1| 1135|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1135
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 836 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 895
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 896 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 955
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 956 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 1015
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 1016 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1073
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1074 NDHQSTLSYILINPSPDTRIELNDVVYLI 1102
Score = 158 bits (383), Expect = 1e-37
Identities = 68/114 (59%), Positives = 90/114 (78%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
NG+YNFI+PLRA++R K LNPI+LLL+ PD+ FLDAI +FP+VY+M+G+ID
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSID 782
>AL138931-1|CAI15624.1| 1111|Homo sapiens potassium channel,
subfamily T, member 2 protein.
Length = 1111
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 454 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 513
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 514 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 568
Query: 340 QAVPN 344
Q N
Sbjct: 569 QRKSN 573
Score = 232 bits (567), Expect = 6e-60
Identities = 125/269 (46%), Positives = 175/269 (65%), Gaps = 31/269 (11%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 812 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 871
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 872 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 931
Query: 787 IGIYRTQDTSMA--------------------DASHHQE------ELDGGDFPACGRQEA 820
IGIYRT+ + + HH+ D D P R+
Sbjct: 932 IGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSM 991
Query: 821 TSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLTGVDYDDV 877
+ P +S A+ + R N ++ ER E+A LV++RM+ L L+ V YD++
Sbjct: 992 Q--WARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEM 1049
Query: 878 SEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ +++LSY++INPS D ++ D++ L+
Sbjct: 1050 NDHQSTLSYILINPSPDTRIELNDVVYLI 1078
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 669 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 728
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 729 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 761
>AK127807-1|BAC87144.1| 523|Homo sapiens protein ( Homo sapiens
cDNA FLJ45908 fis, clone OCBBF3028001, moderately
similar to Rattus norvegicus potassium channel subunit
(Slack) (Slack). ).
Length = 523
Score = 459 bits (1132), Expect = e-128
Identities = 203/305 (66%), Positives = 251/305 (82%), Gaps = 5/305 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 95 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 154
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 155 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 214
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 215 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 274
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASF
Sbjct: 275 TSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASF 334
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+
Sbjct: 335 HAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ 389
Query: 340 QAVPN 344
Q N
Sbjct: 390 QRKSN 394
Score = 53.2 bits (122), Expect = 5e-06
Identities = 21/31 (67%), Positives = 24/31 (77%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQL 581
KG+PP SP+IG SPT C LL EK P CCL+L
Sbjct: 490 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRL 520
>AL158822-4|CAI39240.1| 1315|Homo sapiens potassium channel,
subfamily T, member 1 protein.
Length = 1315
Score = 456 bits (1124), Expect = e-127
Identities = 197/301 (65%), Positives = 250/301 (83%), Gaps = 5/301 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FE+L + WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 412 FEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 471
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M+ EACFIL++RN D+T
Sbjct: 472 ILCPTEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRT 531
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AAD TILR+WAVKDFAP YVQI +PENK HVKFA+ VVCE+E KYA+LA NC CP
Sbjct: 532 AADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPA 591
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQ+SPE+W R+YG+CSGNE+YHI +GDS+FF EYEGKSFTYA+F
Sbjct: 592 TSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAF 651
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+KYGV L+G++ + +ILLNPGPRHI+ ++DTC+Y++ITKEENSAF+ +
Sbjct: 652 HAHKKYGVCLIGLKRED-----NKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQE 706
Query: 340 Q 340
+
Sbjct: 707 E 707
Score = 204 bits (499), Expect = 1e-51
Identities = 93/126 (73%), Positives = 111/126 (88%)
Query: 668 TELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDTL 727
TEL+ SNMRFMQFRA D Y+L LSK+EKRE+E GS++++MFRLPFAAG VFS SMLDTL
Sbjct: 985 TELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRVFSISMLDTL 1044
Query: 728 LYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIPI 787
LYQ+FVKDYMIT RLLLG+D PGSG+L ++KIT+ D+WIRTYGRL+QKLCS+S EIPI
Sbjct: 1045 LYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPI 1104
Query: 788 GIYRTQ 793
GIYRT+
Sbjct: 1105 GIYRTE 1110
Score = 153 bits (370), Expect = 4e-36
Identities = 66/115 (57%), Positives = 91/115 (79%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
VKG+PP SP+IG SPTLC LL K P CCL+L + C+H +Y +AK Y ++NK II++A+
Sbjct: 816 VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAET 875
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++RS+ LNPI+LLL+ +PD FL+AI FP+VY+M G++D
Sbjct: 876 AGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVD 930
Score = 41.1 bits (92), Expect = 0.020
Identities = 22/53 (41%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 855 EIANLVRSR-MESLNLTGVDYDDVSEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
++ANL S M +NL G D++++ +N+LSYV+INP D L+ DI+ L+
Sbjct: 1228 DVANLTASDVMNRVNL-GYLQDEMNDHQNTLSYVLINPPPDTRLEPSDIVYLI 1279
>AB037843-1|BAA92660.1| 1151|Homo sapiens KIAA1422 protein protein.
Length = 1151
Score = 456 bits (1124), Expect = e-127
Identities = 197/301 (65%), Positives = 250/301 (83%), Gaps = 5/301 (1%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FE+L + WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 368 FEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 427
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M+ EACFIL++RN D+T
Sbjct: 428 ILCPTEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRT 487
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
AAD TILR+WAVKDFAP YVQI +PENK HVKFA+ VVCE+E KYA+LA NC CP
Sbjct: 488 AADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPA 547
Query: 220 ASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASF 279
STL+TLL+HTSRGQEGQ+SPE+W R+YG+CSGNE+YHI +GDS+FF EYEGKSFTYA+F
Sbjct: 548 TSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAF 607
Query: 280 HSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDK 339
H+H+KYGV L+G++ + +ILLNPGPRHI+ ++DTC+Y++ITKEENSAF+ +
Sbjct: 608 HAHKKYGVCLIGLKRED-----NKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQE 662
Query: 340 Q 340
+
Sbjct: 663 E 663
Score = 206 bits (502), Expect = 4e-52
Identities = 94/136 (69%), Positives = 114/136 (83%)
Query: 668 TELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDTL 727
TEL+ SNMRFMQFRA D Y+L LSK+EKRE+E GS++++MFRLPFAAG VFS SMLDTL
Sbjct: 941 TELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRVFSISMLDTL 1000
Query: 728 LYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIPI 787
LYQ+FVKDYMIT RLLLG+D PGSG+L ++KIT+ D+WIRTYGRL+QKLCS+S EIPI
Sbjct: 1001 LYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPI 1060
Query: 788 GIYRTQDTSMADASHH 803
GIYRT+ + + H
Sbjct: 1061 GIYRTESHVFSTSEPH 1076
Score = 153 bits (370), Expect = 4e-36
Identities = 66/115 (57%), Positives = 91/115 (79%)
Query: 550 VKGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADY 609
VKG+PP SP+IG SPTLC LL K P CCL+L + C+H +Y +AK Y ++NK II++A+
Sbjct: 772 VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAET 831
Query: 610 ASNGIYNFIIPLRAHFRSKTTLNPIILLLERRPDVAFLDAISYFPLVYWMLGTID 664
A NG+YNFI+PLRA++RS+ LNPI+LLL+ +PD FL+AI FP+VY+M G++D
Sbjct: 832 AGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVD 886
>AK131498-1|BAD18642.1| 1052|Homo sapiens protein ( Homo sapiens
cDNA FLJ16700 fis, clone TRACH3005211, moderately
similar to Rattus norvegicus potassium channel subunit
(Slack) (Slack). ).
Length = 1052
Score = 450 bits (1109), Expect = e-125
Identities = 203/312 (65%), Positives = 251/312 (80%), Gaps = 12/312 (3%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 249 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 308
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 309 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 368
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 369 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 428
Query: 220 ASTLVTLLLHTSRGQ-------EGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGK 272
STL+TLL+HTSRGQ EGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGK
Sbjct: 429 TSTLITLLVHTSRGQCVCLCCREGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGK 488
Query: 273 SFTYASFHSHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENS 332
SFTYASFH+H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENS
Sbjct: 489 SFTYASFHAHKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENS 543
Query: 333 AFVVSDKQAVPN 344
AF D+Q N
Sbjct: 544 AFKNQDQQRKSN 555
Score = 202 bits (492), Expect = 7e-51
Identities = 91/131 (69%), Positives = 113/131 (86%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 794 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 853
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLYQKLCSTSCEIP 786
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLYQKLCS++ ++P
Sbjct: 854 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 913
Query: 787 IGIYRTQDTSM 797
IGIYRT+ +
Sbjct: 914 IGIYRTESQKL 924
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 651 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 710
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 711 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 743
>BC103949-1|AAI03950.1| 1068|Homo sapiens KCNT2 protein protein.
Length = 1068
Score = 304 bits (747), Expect = 9e-82
Identities = 133/197 (67%), Positives = 165/197 (83%)
Query: 40 FEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVV 99
FEQLA+ WMERQK GG+YS HRAQ+EKHVV+C ++L D +MDFLNEFYAHP LQDYYVV
Sbjct: 274 FEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVV 333
Query: 100 LLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKT 159
+L P E+D +R +LQ+P+W+QRVIY+QGS LKD DL+RA+M++AEACFIL++R D+T
Sbjct: 334 ILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRT 393
Query: 160 AADEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPG 219
++D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP
Sbjct: 394 SSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPA 453
Query: 220 ASTLVTLLLHTSRGQEG 236
STL+TLL+HTSRGQ G
Sbjct: 454 TSTLITLLVHTSRGQFG 470
Score = 203 bits (496), Expect = 2e-51
Identities = 120/276 (43%), Positives = 170/276 (61%), Gaps = 38/276 (13%)
Query: 667 ITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGSVFSASMLDT 726
ITEL+ +NMRFMQFRA D Y+L LSK+EK+E+ERGS++++MFRLPFAAG VFS SMLDT
Sbjct: 762 ITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDT 821
Query: 727 LLYQAFVKDYMITFVRLLLGIDQAPGSGFLASIKITKEDMWIRTYGRLY----------- 775
LLYQ+FVKDYMI+ RLLLG+D PGSGFL S+KIT +D+WIRTY RLY
Sbjct: 822 LLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVP 881
Query: 776 --------QKLCSTSC-------EIPIGIYRTQDTSMA-DASHHQEE------LDGGDFP 813
QKL ++ +I I + +DT + + HH+ D D P
Sbjct: 882 IGIYRTESQKLTTSESRKIASQSQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHP 941
Query: 814 ACGRQEATSCLGGCYGERTPVYSTSLAD---EARDNHIQQIERAEIANLVRSRMESLNLT 870
R+ + P +S A+ + R N ++ ER E+A LV++RM+ L L+
Sbjct: 942 LLRRKSMQWARR--LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLS 999
Query: 871 GVDYDDVSEKRNSLSYVIINPSCDLNLQEGDIMNLV 906
V YD++++ +++LSY++INPS D ++ D++ L+
Sbjct: 1000 TVGYDEMNDHQSTLSYILINPSPDTRIELNDVVYLI 1035
Score = 124 bits (298), Expect = 2e-27
Identities = 54/93 (58%), Positives = 70/93 (75%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 619 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 678
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLERRPD 643
NG+YNFI+PLRA++R K LNPI+LLL+ D
Sbjct: 679 GNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLD 711
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/64 (53%), Positives = 43/64 (67%), Gaps = 5/64 (7%)
Query: 281 SHRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDKQ 340
S ++GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+Q
Sbjct: 465 SRGQFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQQ 519
Query: 341 AVPN 344
N
Sbjct: 520 RKSN 523
>BC103947-1|AAI03948.1| 370|Homo sapiens KCNT2 protein protein.
Length = 370
Score = 277 bits (679), Expect = 2e-73
Identities = 123/183 (67%), Positives = 147/183 (80%), Gaps = 5/183 (2%)
Query: 162 DEHTILRSWAVKDFAPKVAQYVQIFRPENKLHVKFAEFVVCEDEFKYALLANNCTCPGAS 221
D TILR+WAVKDFAP YVQI +PENK H+KFA+ VVCE+EFKYA+LA NC CP S
Sbjct: 7 DHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATS 66
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
TL+TLL+HTSRGQEGQQSPE+W ++YG+CSGNE+YHIVL +S FF EYEGKSFTYASFH+
Sbjct: 67 TLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHA 126
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPRHIMKSTDTCYYMSITKEENSAFVVSDKQA 341
H+K+GV L+GVR + ILLNPGPR+IM STD C+Y++ITKEENSAF D+Q
Sbjct: 127 HKKFGVCLIGVRRED-----NKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQQR 181
Query: 342 VPN 344
N
Sbjct: 182 KSN 184
Score = 123 bits (297), Expect = 3e-27
Identities = 53/89 (59%), Positives = 69/89 (77%)
Query: 551 KGFPPVSPFIGVSPTLCFLLKEKKPLCCLQLAQVCEHCAYRNAKEYQWQNKTIILAADYA 610
KG+PP SP+IG SPT C LL EK P CCL+L + C+H Y +AK Y ++NK II+AA+ A
Sbjct: 280 KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETA 339
Query: 611 SNGIYNFIIPLRAHFRSKTTLNPIILLLE 639
NG+YNFI+PLRA++R K LNPI+LLL+
Sbjct: 340 GNGLYNFIVPLRAYYRPKKELNPIVLLLD 368
>U23767-1|AAA92290.1| 1178|Homo sapiens calcium-activated potassium
channel protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>U13913-1|AAA85104.1| 1178|Homo sapiens large-conductance
calcium-activated potassium channel protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>U11717-1|AAC50353.1| 1154|Homo sapiens calcium activated potassium
channel protein.
Length = 1154
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 370 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 425
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 426 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 485
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 486 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 545
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 546 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 598
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 599 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 655
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 656 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 692
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 949 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 982
>U11058-1|AAB65837.1| 1113|Homo sapiens large conductance calcium-
and voltage-dependent potassium channel alpha subuni
protein.
Length = 1113
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 614
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 615 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 651
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 908 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 941
>AY040849-1|AAK91504.1| 1154|Homo sapiens large conductance
calcium-activated potassium channel subfamily M alpha
member protein.
Length = 1154
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 370 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 425
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 426 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 485
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 486 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 545
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 546 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 598
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 599 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 655
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 656 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 692
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 949 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 982
>AL731560-9|CAI40877.1| 1178|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL731560-8|CAI40872.1| 1166|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1166
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 382 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 437
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 438 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 497
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 498 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 557
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 558 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 610
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 611 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 667
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 668 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 704
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 961 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 994
>AL731560-7|CAI40874.1| 1205|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1205
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1000 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1033
>AL731560-6|CAI40875.1| 1181|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1181
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 344 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 399
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 400 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 459
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 460 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 519
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 520 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 572
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 573 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 629
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 630 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 666
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 923 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 956
>AL731560-3|CAI40868.1| 1167|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1167
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 616
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 617 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 653
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 910 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 943
>AL731560-2|CAI40870.1| 1177|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1177
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL731556-10|CAI14082.1| 1178|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL731556-7|CAI14077.1| 1166|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1166
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 382 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 437
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 438 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 497
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 498 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 557
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 558 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 610
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 611 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 667
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 668 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 704
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 961 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 994
>AL731556-6|CAI14076.1| 1181|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1181
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 344 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 399
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 400 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 459
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 460 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 519
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 520 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 572
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 573 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 629
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 630 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 666
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 923 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 956
>AL731556-5|CAI14079.1| 1205|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1205
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1000 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1033
>AL731556-4|CAI14074.1| 1177|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1177
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL731556-1|CAI14073.1| 1167|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1167
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 616
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 617 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 653
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 910 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 943
>AL627447-10|CAI16171.1| 1178|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL627447-8|CAI16169.1| 1181|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1181
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 344 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 399
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 400 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 459
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 460 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 519
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 520 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 572
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 573 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 629
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 630 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 666
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 923 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 956
>AL627447-7|CAI16166.1| 1205|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1205
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1000 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1033
>AL627447-6|CAI16168.1| 1166|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1166
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 382 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 437
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 438 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 497
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 498 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 557
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 558 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 610
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 611 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 667
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 668 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 704
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 961 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 994
>AL627447-2|CAI16162.1| 1177|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1177
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL627447-1|CAI16163.1| 1167|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1167
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 616
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 617 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 653
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 910 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 943
>AL157833-9|CAI39736.1| 1178|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1178
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AL157833-8|CAI39735.1| 1181|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1181
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 344 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 399
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 400 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 459
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 460 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 519
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 520 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 572
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 573 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 629
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 630 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 666
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 923 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 956
>AL157833-7|CAI39734.1| 1205|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1205
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1000 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1033
>AL157833-6|CAI39732.1| 1166|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1166
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 382 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 437
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 438 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 497
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 498 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 557
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 558 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 610
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 611 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 667
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 668 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 704
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 961 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 994
>AL157833-4|CAI39728.1| 1167|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1167
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 616
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 617 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 653
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 910 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 943
>AL157833-3|CAI39730.1| 1177|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1177
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 394 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 449
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 450 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 509
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 510 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 569
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 570 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 622
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 623 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 679
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 680 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 716
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 973 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1006
>AF025999-1|AAB88802.1| 1154|Homo sapiens calcium-activated
potassium channel alpha subunit protein.
Length = 1154
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 370 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 425
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 426 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 485
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 486 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 545
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 546 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 598
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 599 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 655
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 656 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 692
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 949 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 982
>AB113575-1|BAD06397.1| 1195|Homo sapiens BK variant
stretch-activated Kca channel protein.
Length = 1195
Score = 93.1 bits (221), Expect = 5e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 370 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 425
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 426 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 485
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 486 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 545
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 546 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 598
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 599 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 655
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 656 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 692
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 990 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1023
>AF118141-1|AAD31173.1| 1113|Homo sapiens BKCA alpha subunit
protein.
Length = 1113
Score = 92.7 bits (220), Expect = 6e-18
Identities = 89/338 (26%), Positives = 146/338 (43%), Gaps = 26/338 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPD 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSDKQ 340
K + ++ + E IL+NPG I + T + S KE AF K
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC-KA 614
Query: 341 AVPNPTIPK--DQTACSFLSNERNPDEGSTSQQKKPDG 376
+ T PK + C L +E+ P S ++++ G
Sbjct: 615 CHDDITDPKRIKKCGCKRLEDEQ-PSTLSPKKKQRNGG 651
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 908 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 941
>U02632-1|AAA50173.1| 885|Homo sapiens calcium-activated potassium
channel protein.
Length = 885
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 72 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 127
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 128 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 187
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 188 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 247
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 248 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 300
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 301 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 352
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 680 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 713
>AL731560-13|CAI40881.1| 885|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 885
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 72 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 127
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 128 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 187
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 188 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 247
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 248 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 300
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 301 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 352
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 680 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 713
>AL731560-10|CAI40878.1| 1210|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1210
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL731560-5|CAI40873.1| 1171|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1171
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 609
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 966 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 999
>AL731560-4|CAI40871.1| 1209|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1209
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL731560-1|CAI40869.1| 1225|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1225
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 611
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 968 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1001
>AL731556-9|CAI14081.1| 1210|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1210
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL731556-8|CAI14078.1| 1171|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1171
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 609
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 966 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 999
>AL731556-3|CAI14075.1| 1225|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1225
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 611
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 968 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1001
>AL731556-2|CAI14072.1| 1209|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1209
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL627447-9|CAI16172.1| 1210|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1210
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL627447-5|CAI16170.1| 1171|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1171
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 609
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 966 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 999
>AL627447-4|CAI16164.1| 1209|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1209
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL627447-3|CAI16165.1| 1225|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1225
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 611
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 968 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1001
>AL157833-11|CAI39738.1| 885|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 885
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 72 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 127
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 128 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 187
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 188 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 247
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 248 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 300
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 301 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 352
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 680 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 713
>AL157833-10|CAI39737.1| 1210|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1210
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AL157833-5|CAI39733.1| 1171|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1171
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 557
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 558 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 609
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 966 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 999
>AL157833-2|CAI39729.1| 1225|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1225
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 331 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 386
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 387 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 446
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 447 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 506
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 507 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 559
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 560 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 611
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 968 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1001
>AL157833-1|CAI39731.1| 1209|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 1209
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 368 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 423
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 424 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 483
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 484 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 543
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 544 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 596
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 597 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 648
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1005 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1038
>AB113382-1|BAD06365.1| 1212|Homo sapiens stretch-activated Kca
channel protein.
Length = 1212
Score = 91.9 bits (218), Expect = 1e-17
Identities = 79/294 (26%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 370 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 425
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 426 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 485
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 486 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 545
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 546 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 598
Query: 282 HRKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 599 FVKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 650
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 1007 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 1040
>AB209488-1|BAD92725.1| 590|Homo sapiens large conductance
calcium-activated potassium channel subfamily M alpha
member protein.
Length = 590
Score = 91.5 bits (217), Expect = 1e-17
Identities = 86/325 (26%), Positives = 140/325 (43%), Gaps = 25/325 (7%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 255 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 310
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 311 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 370
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 371 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 430
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHS 281
T++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 431 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELC 483
Query: 282 HRKYGVALVGV--RPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAFVVSD 338
K + ++ + + A IL+NPG I + T + S KE AF
Sbjct: 484 FVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYC- 542
Query: 339 KQAVPNPTIPK--DQTACSFLSNER 361
K + T PK + C L +E+
Sbjct: 543 KACHDDITDPKRIKKCGCKRLEDEQ 567
>U09384-1|AAA50216.1| 609|Homo sapiens calcium-activated potassium
channel protein.
Length = 609
Score = 88.2 bits (209), Expect = 1e-16
Identities = 65/226 (28%), Positives = 105/226 (46%), Gaps = 15/226 (6%)
Query: 50 RQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDYYVVLLSPMELDTT 109
R+K GGSYS+ KH+VVC + +++ +FL +F H D V ++ +
Sbjct: 329 RKKYGGSYSA--VSGRKHIVVCGH-ITLESVSNFLKDFL-HKDRDDVNVEIVFLHNISPN 384
Query: 110 MRMILQVPIWAQRVIYIQGSCLKDTDLIRARMNEAEACFILAARNYADKTAADEHTILRS 169
+ + +V + QGS L DL R ++ A+AC ILA + AD A D I+R
Sbjct: 385 LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRV 444
Query: 170 WAVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAS 221
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G S
Sbjct: 445 ISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLS 504
Query: 222 TLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFG 267
T++ L S + + W + Y + NE+Y L S F G
Sbjct: 505 TMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYL-SSAFVG 547
>AL731560-11|CAI40879.1| 263|Homo sapiens potassium large
conductance calcium-activated channel, subfamily M,
alpha membe protein.
Length = 263
Score = 39.1 bits (87), Expect = 0.082
Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 18/173 (10%)
Query: 171 AVKDFAPKVAQYVQIFRPENKLHV--------KFAEFVVCEDEFKYALLANNCTCPGAST 222
++K++ PK+ Q+ + NK H+ K + +C E K +A +C G ST
Sbjct: 3 SIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLST 62
Query: 223 LVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSH 282
++ L S + + W + Y + NE+Y L + + G SF
Sbjct: 63 MLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA-----FVGLSFPTVCELCF 115
Query: 283 RKYGVALVGVRPAELPEFYEDTILLNPGPR-HIMKSTDTCYYMSITKEENSAF 334
K + ++ + E IL+NPG I + T + S KE AF
Sbjct: 116 VKLKLLMIAIEYKSANR--ESRILINPGNHLKIQEGTLGFFIASDAKEVKRAF 166
>AY445624-1|AAS01054.1| 157|Homo sapiens potassium large
conductance calcium-activated channel subfamily M alpha
member protein.
Length = 157
Score = 34.7 bits (76), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 712 PFAAGSVFSASMLDTLLYQAFVKDYMITFVRLLL 745
PFA G+ F+ S+LD+L+ + D ++T +R L+
Sbjct: 71 PFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV 104
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.134 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 152,428,222
Number of Sequences: 224733
Number of extensions: 6351529
Number of successful extensions: 16157
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 15804
Number of HSP's gapped (non-prelim): 282
length of query: 1061
length of database: 73,234,838
effective HSP length: 98
effective length of query: 963
effective length of database: 51,211,004
effective search space: 49316196852
effective search space used: 49316196852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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