Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000698-TA|BGIBMGA000698-PA|IPR002048|Calcium-binding
EF-hand, IPR006573|NEUZ, IPR001220|Legume lectin, beta domain,
IPR011034|Formyl transferase, C-terminal-like
(1612 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB058690-1|BAB47416.1| 1564|Homo sapiens KIAA1787 protein protein. 621 e-177
AL136870-1|CAB66804.1| 1514|Homo sapiens hypothetical protein pr... 617 e-175
BC007227-1|AAH07227.1| 530|Homo sapiens KIAA1787 protein protein. 229 5e-59
BC073134-1|AAH73134.1| 505|Homo sapiens KIAA1787 protein protein. 117 3e-25
BC107485-1|AAI07486.1| 285|Homo sapiens neuralized homolog 2 (D... 50 9e-05
BC105935-1|AAI05936.1| 285|Homo sapiens neuralized homolog 2 (D... 50 9e-05
BC074737-1|AAH74737.1| 285|Homo sapiens neuralized homolog 2 (D... 50 9e-05
AL008726-12|CAC36018.1| 285|Homo sapiens neuralized homolog 2 (... 50 9e-05
AK054821-1|BAB70810.1| 285|Homo sapiens nyltransferase. protein. 50 9e-05
AJ295985-1|CAC82498.1| 285|Homo sapiens hypothetical protein pr... 50 9e-05
BC026336-1|AAH26336.1| 574|Homo sapiens neuralized homolog (Dro... 49 1e-04
U87864-1|AAC17474.1| 574|Homo sapiens neuralized homolog protein. 48 3e-04
AL139339-4|CAH71486.1| 574|Homo sapiens neuralized homolog (Dro... 48 3e-04
AL121929-3|CAI13960.1| 574|Homo sapiens neuralized homolog (Dro... 48 3e-04
AF029729-1|AAD01887.1| 574|Homo sapiens neuralized protein. 48 3e-04
AL121929-2|CAI13959.1| 108|Homo sapiens neuralized homolog (Dro... 37 0.68
AL121929-1|CAI13958.1| 199|Homo sapiens neuralized homolog (Dro... 37 0.68
Z93020-1|CAI21594.1| 729|Homo sapiens RAN binding protein 9 pro... 36 1.6
BC052781-1|AAH52781.1| 802|Homo sapiens RANBP9 protein protein. 36 1.6
BC019886-1|AAH19886.1| 486|Homo sapiens Unknown (protein for IM... 36 1.6
AL441883-5|CAI19841.1| 729|Homo sapiens RAN binding protein 9 p... 36 1.6
AF306510-1|AAK15469.1| 500|Homo sapiens RANBPM protein. 36 1.6
AB055311-1|BAB62525.1| 729|Homo sapiens RanBPM protein. 36 1.6
AB008515-1|BAA23216.1| 500|Homo sapiens RanBPM protein. 36 1.6
AF064606-1|AAC17111.1| 243|Homo sapiens KB07 protein protein. 33 6.4
>AB058690-1|BAB47416.1| 1564|Homo sapiens KIAA1787 protein protein.
Length = 1564
Score = 621 bits (1535), Expect = e-177
Identities = 345/797 (43%), Positives = 482/797 (60%), Gaps = 50/797 (6%)
Query: 214 MSSEGACSS----AQDHLRFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDN 269
+ S GA +S + D L FH +CG L+KLS NNKTAER RPLD++NNGVVMT+RPL DN
Sbjct: 303 LGSSGAATSPILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDN 362
Query: 270 ELFEIRIDRLVDKWSGSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCM 329
E+FEIRID+LVDKWSGS+E+GVTTHNP ++ +P+TMTN+ SGTIMMSGC +L NG GT
Sbjct: 363 EMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRR 422
Query: 330 EYGNFNLDDLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVS 389
EY F+LD+L+E + +GL RKSN LH+FING+DQGVAT P V+GVVDLYGM VKV+
Sbjct: 423 EYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVT 482
Query: 390 IVDPCEDMDSNIQHIPQPMNAID-IAEPRRFRPA--IDEDSLLFHTLRDSNVIIINDGKT 446
IV D ++ + A+ RR PA + + LLFH I ++G+T
Sbjct: 483 IVHNNNHSD-RLRRNNAILRALSPEGALRRAAPAAQAEPERLLFHPNCGQKAAITHEGRT 541
Query: 447 AHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRM 506
A RP+A + FN+GVV+++R LR E+FQVR+D ++ KWAGSIEIGVT H + + P M
Sbjct: 542 ALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTM 601
Query: 507 SNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGP 566
+N +SGTW +TG V+ +GT I+ +Y NL+RL GDTVGV+R++ G LHF+VNG+ QGP
Sbjct: 602 TNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGP 661
Query: 567 AAFNIPEHVFGIIDLYGRVAQATIVD------IYLXXXXXXXXXXXXTESNATVNPEMCF 620
AA+N+P V+ ++DLYG+ AQATIVD + + S+ ++ F
Sbjct: 662 AAWNVPPGVYAVVDLYGQAAQATIVDDVEVAPVPEPLPEGNNQVSPSSPSSGAGGSDLRF 721
Query: 621 HRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEI 680
H++HG NA ++ TA R SEFNDA++ S+R LR+ ++FE+ I KMVD W GS+E
Sbjct: 722 HQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEA 781
Query: 681 GVTAIRPDDLEXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGS 740
GVTAIRP+DLE D+++DT++LSG A+M+DG +R+ Y DLD L G+
Sbjct: 782 GVTAIRPEDLE-------FPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGA 834
Query: 741 RVGMMWHADRSLHYYLDGMDMGKA--WYVPHLNIYAVVDLYGQCTQTCRT--YGSMVN-- 794
R+GMM A LHY+++G D G A P +YAVVDLYGQC Q T G M N
Sbjct: 835 RIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSL 894
Query: 795 ----------------VFGIFRSFSEYCGENVCMMHGCSVARRLTPDPTYALVFSSAHLA 838
V G+ F CG+NV + + A R + LVFS+ L
Sbjct: 895 ATSNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVR-AAGYAHGLVFSTKELR 953
Query: 839 VGEMFEIKIVECKSSYAGSFRMGITDVNILNAHVNRSLPLNISRLPHFTAYIDGKYMKYS 898
E+FE+K+ E +AGS R+G+T + + LP + K +
Sbjct: 954 AEEVFEVKVEELDEKWAGSLRLGLT--TLAPGEMGPGAGGGGPGLPPSLPELRTK-TTWM 1010
Query: 899 KAGCSVK---EKDMRSFVPSFEWLRTGDRLGLKKTSDFKVLVYYNSELLDVAFEKVPDKV 955
+ C V+ + ++ + E L G R+G+++ +D + + + E + A + V
Sbjct: 1011 VSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNV 1070
Query: 956 FAVMELCGPVTKIHTIS 972
+AV++L GPV + +S
Sbjct: 1071 WAVLDLYGPVRGVSIVS 1087
Score = 502 bits (1237), Expect = e-141
Identities = 287/792 (36%), Positives = 441/792 (55%), Gaps = 49/792 (6%)
Query: 3 FHRRCGDRVTLLNDNSTAIRN--FVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
FH +CG + L N+N TA R EFN+G++++ P+ D+ MFE+ ID+ V+ W+GS+E
Sbjct: 322 FHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIE 381
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGP-ELDTLREGDCLGVM 119
IGVTT +P +E PAT T L++ +MSG I+ +G Y LD L+EGD +G+
Sbjct: 382 IGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLT 441
Query: 120 RTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAMELCLVQAE 179
R S + L F+ING GVA PP ++ V+DLYG V+V+I N
Sbjct: 442 RKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNN-------------- 487
Query: 180 DDPNNDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFHPRCGILVKL 239
N+ D L + + L P+ P A + + L FHP CG +
Sbjct: 488 ---NHSDRLRRNNAILRALS----PEGALRRAAP-----AAQAEPERLLFHPNCGQKAAI 535
Query: 240 SGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATI 299
+ +TA R DD+N+GVV++ R L D E+F++RID++VDKW+GS+E+GVTTHNPA +
Sbjct: 536 THEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYL 595
Query: 300 RFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFI 359
+ PSTMTN+ SGT MM+G V+ NG EYG+ NLD L+ +TVG++R+ +G LH+F+
Sbjct: 596 QLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGH-NLDRLKAGDTVGVVRREDGTLHFFV 654
Query: 360 NGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPM-NAIDIAEPRR 418
NG+ QG A V P V+ VVDLYG + +IVD D + +P+P+ + P
Sbjct: 655 NGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVD-----DVEVAPVPEPLPEGNNQVSPSS 709
Query: 419 FRPAIDEDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLD 478
L FH L SN +I N G+TA R N FN+ +V++NR LR ELF++ +
Sbjct: 710 PSSGAGGSDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQ 769
Query: 479 LIIPKWAGSIEIGVTQHTASEFEFPFRMSNAKSGTWAITGEDVIRDGTIIIPQYVRNLNR 538
++ +W+GSIE GVT + EFP M++ TW ++G +++DG + Y +L+
Sbjct: 770 KMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDA 829
Query: 539 LVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIP--EHVFGIIDLYGRVAQATIVDIYLX 596
L G +G+MR G LH+++NG DQG A +P + V+ ++DLYG+ Q +I +
Sbjct: 830 LGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGP 889
Query: 597 XXXXXXXXXXXTESNATVNPEMC-----FHRVHGRNARLSRNRLTASRATVYSEFNDAVL 651
TE + ++ + FH G+N L + A RA Y+ ++
Sbjct: 890 MDNSLATSNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYAH---GLV 946
Query: 652 FSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEXXXXXXXXXX--XXXDLNW- 708
FS++ LR ++FE++++++ + W GSL +G+T + P ++ +L
Sbjct: 947 FSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTK 1006
Query: 709 DTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADRSLHYYLDGMDMGKAWYVP 768
T+++S + +DG+ R Y +L+ L VGSRVG+ AD ++H +DG DMG A
Sbjct: 1007 TTWMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGI 1066
Query: 769 HLNIYAVVDLYG 780
N++AV+DLYG
Sbjct: 1067 AKNVWAVLDLYG 1078
Score = 383 bits (942), Expect = e-105
Identities = 260/814 (31%), Positives = 416/814 (51%), Gaps = 80/814 (9%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFV--EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
FH CG + + ++ TA+R +FNHG++LS+ + D +F+V ID+ V+ W GS+E
Sbjct: 525 FHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIE 584
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
IGVTT +P +++LP+T T LR+ W+M+G+ ++ +G T+++ YG LD L+ GD +GV+R
Sbjct: 585 IGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVR 644
Query: 121 TSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAMELCLVQAED 180
L F++NG G AA ++PP ++AV+DLYGQ Q +I V+ + A E
Sbjct: 645 REDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATI--VDDVEVA-----PVPEP 697
Query: 181 DPNNDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFHPRCGILVKLS 240
P ++ ++ PS+P S GA S LRFH G ++
Sbjct: 698 LPEGNNQVS---------PSSP-------------SSGAGGS---DLRFHQLHGSNAVIT 732
Query: 241 GNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATIR 300
+TA R ++N+ +V+++R L D ELFEI I ++VD+WSGS+E GVT P +
Sbjct: 733 NGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLE 792
Query: 301 FPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFIN 360
FP+TMT++D T M+SG ++ +G+ YG +LD L +G++R + G+LHYFIN
Sbjct: 793 FPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYG-CDLDALGTGARIGMMRTAKGDLHYFIN 851
Query: 361 GVDQGVATDKVEP--QVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPMNAIDIAEPRR 418
G DQG A + P +V+ VVDLYG V+VSI + MD++ + A + + P
Sbjct: 852 GQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNS---LATSNTATEKSFP-- 906
Query: 419 FRPAIDEDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLD 478
+ + FH+ NV + DG A R + +G+V + + LR E+F+V+++
Sbjct: 907 LHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYA---HGLVFSTKELRAEEVFEVKVE 963
Query: 479 LIIPKWAGSIEIGVTQHTASEF---------EFPFRMSNAKS-GTWAITGEDVIRDGTII 528
+ KWAGS+ +G+T E P + ++ TW ++ +V RDG +
Sbjct: 964 ELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQ 1023
Query: 529 IPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQA 588
Y RNL RL G VGV R +H V+G D GPAA I ++V+ ++DLYG V
Sbjct: 1024 RMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGV 1083
Query: 589 TIVD---IYLXXXXXXXXXXXXTESNATVNPEMCFHRVHGRN------------ARLSRN 633
+IV + T S + E H + G+N +N
Sbjct: 1084 SIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKN 1143
Query: 634 RLTAS---RATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDL 690
L ++ AT + +N ++ ++PL + ++RID + W SL +GV P+ L
Sbjct: 1144 ILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERL 1203
Query: 691 EXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADR 750
L ++L G + +G + + +LDT G+ +G+ +
Sbjct: 1204 NFPASACA-------LKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSG 1256
Query: 751 SLHYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQ 784
LH +++G+D G A +A+VDLYGQC Q
Sbjct: 1257 GLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQ 1290
Score = 174 bits (424), Expect = 2e-42
Identities = 127/403 (31%), Positives = 195/403 (48%), Gaps = 34/403 (8%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FH CG VTL D + A+R + HGL+ S + + + +FEV ++ W GSL +
Sbjct: 917 RFHSTCGKNVTLEEDGTRAVRA-AGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 975
Query: 62 GVTTLDPEFME---------LPATATKLRN-TAWIMSGSSIVKDGVTLVNSYGPELDTLR 111
G+TTL P M LP + +LR T W++S + +DG +YG L+ L
Sbjct: 976 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLG 1035
Query: 112 EGDCLGVMRTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAM 171
G +GV R + + ++G +G AA + ++AV+DLYG VSI L +
Sbjct: 1036 VGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEES- 1094
Query: 172 ELCLVQAEDDPN-NDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFH 230
+ P+ + DT + E D G ++ + G + + L H
Sbjct: 1095 -----EGTQPPSPSSDTGSEGEEDDEG---------EEHGLGGQNEVGIIPTTLEFLENH 1140
Query: 231 PRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVG 290
G + LS N+TA R YN G+V+ ++PL L ++RID L +W+ S+ +G
Sbjct: 1141 ---GKNILLSNGNRTATRVA---SYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLG 1194
Query: 291 VTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRK 350
V T P + FP++ + ++ G V NG C ++G NLD E +GL
Sbjct: 1195 VITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGP-NLDTCPEGTILGLRLD 1253
Query: 351 SNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDP 393
S+G LH +NGVDQGVA V +VDLYG +V+IV+P
Sbjct: 1254 SSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVNP 1296
Score = 172 bits (419), Expect = 8e-42
Identities = 117/386 (30%), Positives = 182/386 (47%), Gaps = 28/386 (7%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH CG V L + A RA Y +G+V + + L E+FE++++ L +KW+GS+
Sbjct: 917 RFHSTCGKNVTLEEDGTRAVRAA---GYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSL 973
Query: 288 EVGVTTHNPATIR---------FPSTMTNMDSGTI-MMSGCKVLLNGHGTCMEYGNFNLD 337
+G+TT P + P ++ + + T M+S C+V +G M YG NL+
Sbjct: 974 RLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGR-NLE 1032
Query: 338 DLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDM 397
L VG+ R ++ +H ++G D G A + VW V+DLYG VSIV
Sbjct: 1033 RLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLE 1092
Query: 398 DSNIQHIPQPMNAI-------DIAEPRRF----RPAIDEDSLLFHTLRDSNVIIINDGKT 446
+S P P + D E I +L F N+++ N +T
Sbjct: 1093 ESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNGNRT 1152
Query: 447 AHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRM 506
A R ++ N G+V+ N+ L L QVR+D + +W S+ +GV FP
Sbjct: 1153 ATRVASY---NQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASA 1209
Query: 507 SNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGP 566
K W + G V +G I ++ NL+ EG +G+ G LH +VNG+DQG
Sbjct: 1210 CALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGV 1269
Query: 567 AAFNIPEHVFGIIDLYGRVAQATIVD 592
A ++P+ ++DLYG+ Q TIV+
Sbjct: 1270 AVPDVPQPCHALVDLYGQCEQVTIVN 1295
Score = 171 bits (415), Expect = 2e-41
Identities = 81/162 (50%), Positives = 113/162 (69%), Gaps = 2/162 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFV--EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
+ H R G V+L TA R EFNHGL+LS EP+ D +F V IDRKVN W+GS+
Sbjct: 45 ELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSI 104
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVM 119
EIGVT LDP ++ P++AT L+ +W++SG S+++DG +++ YG +LD L EGD +GV
Sbjct: 105 EIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVE 164
Query: 120 RTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSI 161
RT EL ++NGR GVAA LPPR++AV+DLYG+C Q+++
Sbjct: 165 RTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITV 206
Score = 158 bits (384), Expect = 1e-37
Identities = 73/164 (44%), Positives = 107/164 (65%), Gaps = 1/164 (0%)
Query: 230 HPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEV 289
HPR G LV LS +TA R +P ++N+G+V++ PL D +F +RIDR V+ WSGS+E+
Sbjct: 47 HPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEI 106
Query: 290 GVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLR 349
GVT +P+ + FPS+ T + G+ ++SGC VL +G EYG +LD L E + VG+ R
Sbjct: 107 GVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQ-DLDQLGEGDRVGVER 165
Query: 350 KSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDP 393
GEL ++NG D GVA + P+VW VVDLYG +++++ P
Sbjct: 166 TVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPP 209
Score = 151 bits (366), Expect = 2e-35
Identities = 71/170 (41%), Positives = 110/170 (64%), Gaps = 4/170 (2%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFV--EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGS 58
++FH+ G + N TA+R+ EFN +++S + D +FE+ I + V+ W+GS
Sbjct: 719 LRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGS 778
Query: 59 LEIGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGV 118
+E GVT + PE +E P T T + W++SG++I++DG T+ N+YG +LD L G +G+
Sbjct: 779 IEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGM 838
Query: 119 MRTSKAELTFYINGRCLGVAAKDLPP--RLFAVIDLYGQCVQVSISQVNG 166
MRT+K +L ++ING+ G A LPP ++AV+DLYGQCVQVSI+ G
Sbjct: 839 MRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATG 888
Score = 130 bits (313), Expect = 5e-29
Identities = 61/148 (41%), Positives = 92/148 (62%)
Query: 444 GKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFP 503
G+TA R + FN+G+V++ LR +F VR+D + W+GSIEIGVT S +FP
Sbjct: 60 GRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFP 119
Query: 504 FRMSNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGID 563
+ K G+W ++G V+RDG ++ +Y ++L++L EGD VGV R G L +VNG D
Sbjct: 120 SSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRD 179
Query: 564 QGPAAFNIPEHVFGIIDLYGRVAQATIV 591
G AA +P V+ ++DLYG+ Q T++
Sbjct: 180 CGVAATGLPPRVWAVVDLYGKCTQITVL 207
Score = 117 bits (282), Expect = 3e-25
Identities = 58/161 (36%), Positives = 88/161 (54%), Gaps = 1/161 (0%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
++F G + L N N TA R +N G+++ +P+ ++ +V ID W SL
Sbjct: 1134 LEFLENHGKNILLSNGNRTATR-VASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLV 1192
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
+GV T PE + PA+A L+ AW++ G + +G+ + +GP LDT EG LG+
Sbjct: 1193 LGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRL 1252
Query: 121 TSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSI 161
S L ++NG GVA D+P A++DLYGQC QV+I
Sbjct: 1253 DSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTI 1293
Score = 100 bits (240), Expect = 4e-20
Identities = 61/164 (37%), Positives = 86/164 (52%), Gaps = 7/164 (4%)
Query: 621 HRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEI 680
H GR LS TA R EFN ++ S PLR+ +F +RID+ V+ W GS+EI
Sbjct: 47 HPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEI 106
Query: 681 GVTAIRPDDLEXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGS 740
GVTA+ P L+ L ++++SG ++++DG V Y DLD L G
Sbjct: 107 GVTALDPSVLD-------FPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGD 159
Query: 741 RVGMMWHADRSLHYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQ 784
RVG+ L +++G D G A ++AVVDLYG+CTQ
Sbjct: 160 RVGVERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQ 203
Score = 81.4 bits (192), Expect = 2e-14
Identities = 112/440 (25%), Positives = 186/440 (42%), Gaps = 57/440 (12%)
Query: 819 ARRLTPDPTY--ALVFSSAHLAVGEMFEIKIVECKSSYAGSFRMGITDVNILNAHVNRSL 876
ARR P + LV S L G +F ++I +S++GS +G+T +L
Sbjct: 63 ARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVT-----------AL 111
Query: 877 PLNISRLPHFTAYIDGKYMKYSKAGCSVKEKDMRSFVPSF----EWLRTGDRLGLKKTSD 932
++ P + G + +GCSV +D RS + + + L GDR+G+++T
Sbjct: 112 DPSVLDFPSSATGLKGG--SWVVSGCSVL-RDGRSVLEEYGQDLDQLGEGDRVGVERTVA 168
Query: 933 FKVLVYYNSELLDVAFEKVPDKVFAVMELCGPVTKIHTISMAGGVAASNTTTIPNKSIPK 992
++ ++ N VA +P +V+AV++L G T+I + G S T IP +
Sbjct: 169 GELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPPEPGF--SPPTPIPTPPLEP 226
Query: 993 RQPQLNEDGTICPVSTSANMDRETDNQFGIGNEPSTSNTESNKNVRENLIASIDTANTES 1052
P ED + TSA D F + + T N N A+++ + S
Sbjct: 227 LAP--TEDSALAEQGTSA------DEAFMVSPAQARPETFPNSLESHNDFANMELSEVVS 278
Query: 1053 NTMST----------LTVVPT-----ETRRRRNPL-----PYTFHYVHGKNIKLCSSDTV 1092
NT+ + L+ P + +P+ FH G IKL +++
Sbjct: 279 NTILSAYNGGLLNVNLSSPPAGEGLGSSGAATSPILTSNDALLFHEKCGTLIKLSNNNKT 338
Query: 1093 AVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGIGAVGHLA-SEELPPTA 1148
A R + +G+ + ++PLR F RIDK++ W GS+ IG H S E P T
Sbjct: 339 AERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATM 398
Query: 1149 MQLEPPVWVITSDLIYDNGDYIKTKR-GAPLDNLTEQSVLTIHFRLNSDIAVDIDSEPLG 1207
L+ +++ I NG + + LD L E + + + NS + I+ G
Sbjct: 399 TNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQG 458
Query: 1208 VIGAVSRNACHVFPLIDLYG 1227
V A V+ ++DLYG
Sbjct: 459 V--ATPLTPPVVYGVVDLYG 476
Score = 72.9 bits (171), Expect = 8e-12
Identities = 48/164 (29%), Positives = 78/164 (47%), Gaps = 7/164 (4%)
Query: 1072 LPYTFHYV--HGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLG 1129
+P T ++ HGKNI L + + A R + Y G+ +I+QPL + RID + W
Sbjct: 1130 IPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTS 1189
Query: 1130 SVGIGAVGHLASEEL--PPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVL 1187
S+ +G + A E L P +A L+ W++ ++ NG I K G LD E ++L
Sbjct: 1190 SLVLGVI-TCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTIL 1248
Query: 1188 TIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
+ + + + ++ GV CH L+DLYG+ Q
Sbjct: 1249 GLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHA--LVDLYGQCEQ 1290
Score = 62.9 bits (146), Expect = 9e-09
Identities = 39/160 (24%), Positives = 71/160 (44%), Gaps = 4/160 (2%)
Query: 1076 FHYVHGKNIKLCSSDTVAVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVG 1132
FH +HG N + + A+R S + D + I ++ LR G F I K++ W GS+
Sbjct: 721 FHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIE 780
Query: 1133 IGAVGHLASE-ELPPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHF 1191
G + E P T ++ W+++ I +G+ ++ G LD L + + +
Sbjct: 781 AGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMR 840
Query: 1192 RLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
D+ I+ + G + V+ ++DLYG+ Q
Sbjct: 841 TAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQ 880
Score = 62.5 bits (145), Expect = 1e-08
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Query: 1076 FHYVHGKNIKLCSSDTVAVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVG 1132
FH G+ + A+R T + G+ + S+ LR G F+ RIDK++ W GS+
Sbjct: 525 FHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIE 584
Query: 1133 IGAVGH-LASEELPPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHF 1191
IG H A +LP T L W++T + + NG I + G LD L + +
Sbjct: 585 IGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVR 644
Query: 1192 RLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
R + + ++ G A V+ ++DLYG+ Q
Sbjct: 645 REDGTLHFFVNGMTQG--PAAWNVPPGVYAVVDLYGQAAQ 682
Score = 59.7 bits (138), Expect = 8e-08
Identities = 45/167 (26%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 1074 YTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGI 1133
+ FH GKN+ L T AVR +GY GL ++ LR F +++++ W GS+ +
Sbjct: 916 HRFHSTCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 975
Query: 1134 G----AVGHL------ASEELPPTAMQLE-PPVWVITSDLIYDNGDYIKTKRGAPLDNLT 1182
G A G + LPP+ +L W+++S + +G + G L+ L
Sbjct: 976 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLG 1035
Query: 1183 EQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRV 1229
S + + + + + +D E +G A + A +V+ ++DLYG V
Sbjct: 1036 VGSRVGVRRGADDTMHILVDGEDMG--PAATGIAKNVWAVLDLYGPV 1080
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 1099 YKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGIGAVGHLASE-ELPPTAMQLEPPVWV 1157
+ GL + +PLR G F RID+ + W GS+ IG S + P +A L+ WV
Sbjct: 72 FNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWV 131
Query: 1158 ITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRNAC 1217
++ + +G + + G LD L E + + + ++ + ++ GV A +
Sbjct: 132 VSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGV--AATGLPP 189
Query: 1218 HVFPLIDLYGRVTQ 1231
V+ ++DLYG+ TQ
Sbjct: 190 RVWAVVDLYGKCTQ 203
>AL136870-1|CAB66804.1| 1514|Homo sapiens hypothetical protein
protein.
Length = 1514
Score = 617 bits (1523), Expect = e-175
Identities = 342/795 (43%), Positives = 479/795 (60%), Gaps = 48/795 (6%)
Query: 214 MSSEGACSS----AQDHLRFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDN 269
+ S GA +S + D L FH +CG L+KLS NNKTAER RPLD++NNGVVMT+RPL N
Sbjct: 255 LGSSGAATSPILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRGN 314
Query: 270 ELFEIRIDRLVDKWSGSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCM 329
E+FEIRID+LVDKWSGS+E+GVTTHNP ++ +P+TMTN+ SGTIMMSGC +L NG GT
Sbjct: 315 EMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRR 374
Query: 330 EYGNFNLDDLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVS 389
EY F+LD+L+E + +GL RKSN LH+FING+DQGVAT P V+GVVDLYGM VKV+
Sbjct: 375 EYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVT 434
Query: 390 IVDPCEDMDSNIQHIPQPMNAID-IAEPRRFRPA--IDEDSLLFHTLRDSNVIIINDGKT 446
IV D ++ + A+ RR PA + + LLFH I ++G+T
Sbjct: 435 IVHNNNHSD-RLRRNNAILRALSPEGALRRAAPAAQAEPERLLFHPNCGQKAAITHEGRT 493
Query: 447 AHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRM 506
A RP+A + FN+GVV+++R LR E+FQVR+D ++ KWAGSIEIGVT H + + P M
Sbjct: 494 ALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTM 553
Query: 507 SNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGP 566
+N +SGTW +TG V+ +GT I+ +Y NL+RL GD VGV+R++ G LHF+VNG+ QGP
Sbjct: 554 TNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDAVGVVRREDGTLHFFVNGMTQGP 613
Query: 567 AAFNIPEHVFGIIDLYGRVAQATIVD------IYLXXXXXXXXXXXXTESNATVNPEMCF 620
AA+N+P V+ ++DLYG+ AQATIVD + + S+ ++ F
Sbjct: 614 AAWNVPPGVYAVVDLYGQAAQATIVDDVEVAPVPEPLPEGNNQVSPSSPSSGAGGSDLRF 673
Query: 621 HRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEI 680
H++HG NA ++ TA R SEFNDA++ S+R LR+ ++FE+ I KMVD W GS+E
Sbjct: 674 HQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEA 733
Query: 681 GVTAIRPDDLEXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGS 740
GVTAIRP+DLE D+++DT++LSG A+M+DG +R+ Y DLD L G+
Sbjct: 734 GVTAIRPEDLE-------FPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGA 786
Query: 741 RVGMMWHADRSLHYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQTCRT--YGSMVN---- 794
R+GMM A LHY+++G D G A +YAVVDLYGQC Q T G M N
Sbjct: 787 RIGMMRTAKGDLHYFINGQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNSLAT 846
Query: 795 --------------VFGIFRSFSEYCGENVCMMHGCSVARRLTPDPTYALVFSSAHLAVG 840
V G+ F CG+NV + + A R + LVFS+ L
Sbjct: 847 SNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVR-AAGYAHGLVFSTKELRAE 905
Query: 841 EMFEIKIVECKSSYAGSFRMGITDVNILNAHVNRSLPLNISRLPHFTAYIDGKYMKYSKA 900
E+FE+K+ E +AGS R+G+T + + LP + K + +
Sbjct: 906 EVFEVKVEELDEKWAGSLRLGLT--TLAPGEMGPGAGGGGPGLPPSLPELRTK-TTWMVS 962
Query: 901 GCSVK---EKDMRSFVPSFEWLRTGDRLGLKKTSDFKVLVYYNSELLDVAFEKVPDKVFA 957
C V+ + ++ + E L G R+G+++ +D + + + E + A + V+A
Sbjct: 963 SCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWA 1022
Query: 958 VMELCGPVTKIHTIS 972
V++L GPV + +S
Sbjct: 1023 VLDLYGPVRGVSIVS 1037
Score = 501 bits (1236), Expect = e-141
Identities = 285/790 (36%), Positives = 438/790 (55%), Gaps = 47/790 (5%)
Query: 3 FHRRCGDRVTLLNDNSTAIRN--FVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
FH +CG + L N+N TA R EFN+G++++ P+ + MFE+ ID+ V+ W+GS+E
Sbjct: 274 FHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRGNEMFEIRIDKLVDKWSGSIE 333
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGP-ELDTLREGDCLGVM 119
IGVTT +P +E PAT T L++ +MSG I+ +G Y LD L+EGD +G+
Sbjct: 334 IGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLT 393
Query: 120 RTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAMELCLVQAE 179
R S + L F+ING GVA PP ++ V+DLYG V+V+I N
Sbjct: 394 RKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNN-------------- 439
Query: 180 DDPNNDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFHPRCGILVKL 239
N+ D L + + L P+ P A + + L FHP CG +
Sbjct: 440 ---NHSDRLRRNNAILRALS----PEGALRRAAP-----AAQAEPERLLFHPNCGQKAAI 487
Query: 240 SGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATI 299
+ +TA R DD+N+GVV++ R L D E+F++RID++VDKW+GS+E+GVTTHNPA +
Sbjct: 488 THEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYL 547
Query: 300 RFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFI 359
+ PSTMTN+ SGT MM+G V+ NG EYG+ NLD L+ + VG++R+ +G LH+F+
Sbjct: 548 QLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGH-NLDRLKAGDAVGVVRREDGTLHFFV 606
Query: 360 NGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPM-NAIDIAEPRR 418
NG+ QG A V P V+ VVDLYG + +IVD D + +P+P+ + P
Sbjct: 607 NGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVD-----DVEVAPVPEPLPEGNNQVSPSS 661
Query: 419 FRPAIDEDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLD 478
L FH L SN +I N G+TA R N FN+ +V++NR LR ELF++ +
Sbjct: 662 PSSGAGGSDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQ 721
Query: 479 LIIPKWAGSIEIGVTQHTASEFEFPFRMSNAKSGTWAITGEDVIRDGTIIIPQYVRNLNR 538
++ +W+GSIE GVT + EFP M++ TW ++G +++DG + Y +L+
Sbjct: 722 KMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDA 781
Query: 539 LVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQATIVDIYLXXX 598
L G +G+MR G LH+++NG DQG A +P V+ ++DLYG+ Q +I +
Sbjct: 782 LGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATGPMD 841
Query: 599 XXXXXXXXXTESNATVNPEMC-----FHRVHGRNARLSRNRLTASRATVYSEFNDAVLFS 653
TE + ++ + FH G+N L + A RA Y+ ++FS
Sbjct: 842 NSLATSNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYAH---GLVFS 898
Query: 654 SRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEXXXXXXXXXX--XXXDLNW-DT 710
++ LR ++FE++++++ + W GSL +G+T + P ++ +L T
Sbjct: 899 TKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTT 958
Query: 711 YILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADRSLHYYLDGMDMGKAWYVPHL 770
+++S + +DG+ R Y +L+ L VGSRVG+ AD ++H +DG DMG A
Sbjct: 959 WMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAK 1018
Query: 771 NIYAVVDLYG 780
N++AV+DLYG
Sbjct: 1019 NVWAVLDLYG 1028
Score = 388 bits (956), Expect = e-107
Identities = 260/812 (32%), Positives = 416/812 (51%), Gaps = 78/812 (9%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFV--EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
FH CG + + ++ TA+R +FNHG++LS+ + D +F+V ID+ V+ W GS+E
Sbjct: 477 FHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIE 536
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
IGVTT +P +++LP+T T LR+ W+M+G+ ++ +G T+++ YG LD L+ GD +GV+R
Sbjct: 537 IGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDAVGVVR 596
Query: 121 TSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAMELCLVQAED 180
L F++NG G AA ++PP ++AV+DLYGQ Q +I V+ + A E
Sbjct: 597 REDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATI--VDDVEVA-----PVPEP 649
Query: 181 DPNNDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFHPRCGILVKLS 240
P ++ ++ PS+P S GA S LRFH G ++
Sbjct: 650 LPEGNNQVS---------PSSP-------------SSGAGGS---DLRFHQLHGSNAVIT 684
Query: 241 GNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATIR 300
+TA R ++N+ +V+++R L D ELFEI I ++VD+WSGS+E GVT P +
Sbjct: 685 NGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLE 744
Query: 301 FPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFIN 360
FP+TMT++D T M+SG ++ +G+ YG +LD L +G++R + G+LHYFIN
Sbjct: 745 FPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYG-CDLDALGTGARIGMMRTAKGDLHYFIN 803
Query: 361 GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPMNAIDIAEPRRFR 420
G DQG A + P+V+ VVDLYG V+VSI + MD++ + A + + P
Sbjct: 804 GQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNS---LATSNTATEKSFP--LH 858
Query: 421 PAIDEDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLI 480
+ + FH+ NV + DG A R + +G+V + + LR E+F+V+++ +
Sbjct: 859 SPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYA---HGLVFSTKELRAEEVFEVKVEEL 915
Query: 481 IPKWAGSIEIGVTQHTASEF---------EFPFRMSNAKS-GTWAITGEDVIRDGTIIIP 530
KWAGS+ +G+T E P + ++ TW ++ +V RDG +
Sbjct: 916 DEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRM 975
Query: 531 QYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQATI 590
Y RNL RL G VGV R +H V+G D GPAA I ++V+ ++DLYG V +I
Sbjct: 976 NYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSI 1035
Query: 591 VD---IYLXXXXXXXXXXXXTESNATVNPEMCFHRVHGRN------------ARLSRNRL 635
V + T S + E H + G+N +N L
Sbjct: 1036 VSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNIL 1095
Query: 636 TAS---RATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEX 692
++ AT + +N ++ ++PL + ++RID + W SL +GV P+ L
Sbjct: 1096 LSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNF 1155
Query: 693 XXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADRSL 752
L ++L G + +G + + +LDT G+ +G+ + L
Sbjct: 1156 PASACA-------LKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGL 1208
Query: 753 HYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQ 784
H +++G+D G A +A+VDLYGQC Q
Sbjct: 1209 HLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQ 1240
Score = 233 bits (570), Expect = 4e-60
Identities = 183/613 (29%), Positives = 288/613 (46%), Gaps = 65/613 (10%)
Query: 426 DSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWA 485
D+LLFH + + + N+ KTA R + FNNGVVMTNR LR NE+F++R+D ++ KW+
Sbjct: 270 DALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRGNEMFEIRIDKLVDKWS 329
Query: 486 GSIEIGVTQHTASEFEFPFRMSNAKSGTWAITGEDVIRDGTIIIPQYVR-NLNRLVEGDT 544
GSIEIGVT H + E+P M+N +SGT ++G ++ +G +Y +L+ L EGD
Sbjct: 330 GSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDH 389
Query: 545 VGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQATIV-----------DI 593
+G+ RK LHF++NGIDQG A P V+G++DLYG + TIV +
Sbjct: 390 IGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDRLRRNN 449
Query: 594 YLXXXXXXXXXXXXTESNATVNPE-MCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLF 652
+ A PE + FH G+ A ++ TA R +FN V+
Sbjct: 450 AILRALSPEGALRRAAPAAQAEPERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVL 509
Query: 653 SSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEXXXXXXXXXXXXXDLNWDTYI 712
SSR LR+ ++F++RIDKMVD W GS+EIGVT P L+ +L T++
Sbjct: 510 SSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMT-------NLRSGTWM 562
Query: 713 LSGAAMMKDGECVRSGYPLDLDTLTVGSRV---------------GMM-----WHADRSL 752
++G +M +G + Y +LD L G V GM W+ +
Sbjct: 563 MTGNGVMHNGTTILDEYGHNLDRLKAGDAVGVVRREDGTLHFFVNGMTQGPAAWNVPPGV 622
Query: 753 HYYLDGMDMG-KAWYVPHLNIYAVVDLYGQCTQTCRTYGSMVNVFGIFRSFSEYCGENVC 811
+ +D +A V + + V + + G F + G N
Sbjct: 623 YAVVDLYGQAAQATIVDDVEVAPVPEPLPEGNNQVSPSSPSSGAGGSDLRFHQLHGSNAV 682
Query: 812 MMHGCSVARRLTPDPTY--ALVFSSAHLAVGEMFEIKIVECKSSYAGSFRMGITDVNILN 869
+ +G A R + A+V S+ L GE+FEI I + ++GS G+T +
Sbjct: 683 ITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIR--- 739
Query: 870 AHVNRSLPLNISRLPHFTAYIDGKYMKYSKAGCSVKE--KDMRS-FVPSFEWLRTGDRLG 926
P ++ P+ ID Y + +G ++ + MR+ + + L TG R+G
Sbjct: 740 -------PEDLE-FPNTMTDID--YDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIG 789
Query: 927 LKKTSDFKVLVYYNSELLDVAFEKVPDKVFAVMELCGPVTKIHTISMAG----GVAASNT 982
+ +T+ + + N + A +P +V+AV++L G ++ + G +A SNT
Sbjct: 790 MMRTAKGDLHYFINGQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT 849
Query: 983 TTIPNKSIPKRQP 995
T KS P P
Sbjct: 850 AT--EKSFPLHSP 860
Score = 174 bits (424), Expect = 2e-42
Identities = 127/403 (31%), Positives = 195/403 (48%), Gaps = 34/403 (8%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FH CG VTL D + A+R + HGL+ S + + + +FEV ++ W GSL +
Sbjct: 867 RFHSTCGKNVTLEEDGTRAVRA-AGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 925
Query: 62 GVTTLDPEFME---------LPATATKLRN-TAWIMSGSSIVKDGVTLVNSYGPELDTLR 111
G+TTL P M LP + +LR T W++S + +DG +YG L+ L
Sbjct: 926 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLG 985
Query: 112 EGDCLGVMRTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAM 171
G +GV R + + ++G +G AA + ++AV+DLYG VSI L +
Sbjct: 986 VGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEES- 1044
Query: 172 ELCLVQAEDDPN-NDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFH 230
+ P+ + DT + E D G ++ + G + + L H
Sbjct: 1045 -----EGTQPPSPSSDTGSEGEEDDEG---------EEHGLGGQNEVGIIPTTLEFLENH 1090
Query: 231 PRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVG 290
G + LS N+TA R YN G+V+ ++PL L ++RID L +W+ S+ +G
Sbjct: 1091 ---GKNILLSNGNRTATRVA---SYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLG 1144
Query: 291 VTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRK 350
V T P + FP++ + ++ G V NG C ++G NLD E +GL
Sbjct: 1145 VITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGP-NLDTCPEGTILGLRLD 1203
Query: 351 SNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDP 393
S+G LH +NGVDQGVA V +VDLYG +V+IV+P
Sbjct: 1204 SSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVNP 1246
Score = 172 bits (419), Expect = 8e-42
Identities = 117/386 (30%), Positives = 182/386 (47%), Gaps = 28/386 (7%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH CG V L + A RA Y +G+V + + L E+FE++++ L +KW+GS+
Sbjct: 867 RFHSTCGKNVTLEEDGTRAVRAA---GYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSL 923
Query: 288 EVGVTTHNPATIR---------FPSTMTNMDSGTI-MMSGCKVLLNGHGTCMEYGNFNLD 337
+G+TT P + P ++ + + T M+S C+V +G M YG NL+
Sbjct: 924 RLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGR-NLE 982
Query: 338 DLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDM 397
L VG+ R ++ +H ++G D G A + VW V+DLYG VSIV
Sbjct: 983 RLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLE 1042
Query: 398 DSNIQHIPQPMNAI-------DIAEPRRF----RPAIDEDSLLFHTLRDSNVIIINDGKT 446
+S P P + D E I +L F N+++ N +T
Sbjct: 1043 ESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNGNRT 1102
Query: 447 AHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRM 506
A R ++ N G+V+ N+ L L QVR+D + +W S+ +GV FP
Sbjct: 1103 ATRVASY---NQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASA 1159
Query: 507 SNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGP 566
K W + G V +G I ++ NL+ EG +G+ G LH +VNG+DQG
Sbjct: 1160 CALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGV 1219
Query: 567 AAFNIPEHVFGIIDLYGRVAQATIVD 592
A ++P+ ++DLYG+ Q TIV+
Sbjct: 1220 AVPDVPQPCHALVDLYGQCEQVTIVN 1245
Score = 168 bits (408), Expect = 2e-40
Identities = 73/136 (53%), Positives = 103/136 (75%)
Query: 26 EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIGVTTLDPEFMELPATATKLRNTAW 85
EFNHGL+LS EP+ D +F V IDRKVN W+GS+EIGVT LDP ++ P++AT L+ +W
Sbjct: 23 EFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSW 82
Query: 86 IMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTSKAELTFYINGRCLGVAAKDLPPR 145
++SG S+++DG +++ YG +LD L EGD +GV RT EL ++NGR GVAA LPPR
Sbjct: 83 VVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPR 142
Query: 146 LFAVIDLYGQCVQVSI 161
++AV+DLYG+C Q+++
Sbjct: 143 VWAVVDLYGKCTQITV 158
Score = 156 bits (379), Expect = 5e-37
Identities = 71/168 (42%), Positives = 110/168 (65%), Gaps = 2/168 (1%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFV--EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGS 58
++FH+ G + N TA+R+ EFN +++S + D +FE+ I + V+ W+GS
Sbjct: 671 LRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGS 730
Query: 59 LEIGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGV 118
+E GVT + PE +E P T T + W++SG++I++DG T+ N+YG +LD L G +G+
Sbjct: 731 IEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGM 790
Query: 119 MRTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNG 166
MRT+K +L ++ING+ G A LPP ++AV+DLYGQCVQVSI+ G
Sbjct: 791 MRTAKGDLHYFINGQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATG 838
Score = 152 bits (369), Expect = 9e-36
Identities = 71/162 (43%), Positives = 105/162 (64%), Gaps = 1/162 (0%)
Query: 232 RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGV 291
R G LV LS +TA R +P ++N+G+V++ PL D +F +RIDR V+ WSGS+E+GV
Sbjct: 1 RTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGV 60
Query: 292 TTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKS 351
T +P+ + FPS+ T + G+ ++SGC VL +G EYG +LD L E + VG+ R
Sbjct: 61 TALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQ-DLDQLGEGDRVGVERTV 119
Query: 352 NGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDP 393
GEL ++NG D GVA + P+VW VVDLYG +++++ P
Sbjct: 120 AGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPP 161
Score = 130 bits (313), Expect = 5e-29
Identities = 61/148 (41%), Positives = 92/148 (62%)
Query: 444 GKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFP 503
G+TA R + FN+G+V++ LR +F VR+D + W+GSIEIGVT S +FP
Sbjct: 12 GRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFP 71
Query: 504 FRMSNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGID 563
+ K G+W ++G V+RDG ++ +Y ++L++L EGD VGV R G L +VNG D
Sbjct: 72 SSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRD 131
Query: 564 QGPAAFNIPEHVFGIIDLYGRVAQATIV 591
G AA +P V+ ++DLYG+ Q T++
Sbjct: 132 CGVAATGLPPRVWAVVDLYGKCTQITVL 159
Score = 117 bits (282), Expect = 3e-25
Identities = 58/161 (36%), Positives = 88/161 (54%), Gaps = 1/161 (0%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
++F G + L N N TA R +N G+++ +P+ ++ +V ID W SL
Sbjct: 1084 LEFLENHGKNILLSNGNRTATR-VASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLV 1142
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
+GV T PE + PA+A L+ AW++ G + +G+ + +GP LDT EG LG+
Sbjct: 1143 LGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRL 1202
Query: 121 TSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSI 161
S L ++NG GVA D+P A++DLYGQC QV+I
Sbjct: 1203 DSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTI 1243
Score = 100 bits (239), Expect = 5e-20
Identities = 60/160 (37%), Positives = 85/160 (53%), Gaps = 7/160 (4%)
Query: 625 GRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTA 684
GR LS TA R EFN ++ S PLR+ +F +RID+ V+ W GS+EIGVTA
Sbjct: 3 GRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTA 62
Query: 685 IRPDDLEXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGM 744
+ P L+ L ++++SG ++++DG V Y DLD L G RVG+
Sbjct: 63 LDPSVLD-------FPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGV 115
Query: 745 MWHADRSLHYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQ 784
L +++G D G A ++AVVDLYG+CTQ
Sbjct: 116 ERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQ 155
Score = 81.8 bits (193), Expect = 2e-14
Identities = 112/440 (25%), Positives = 187/440 (42%), Gaps = 57/440 (12%)
Query: 819 ARRLTPDPTY--ALVFSSAHLAVGEMFEIKIVECKSSYAGSFRMGITDVNILNAHVNRSL 876
ARR P + LV S L G +F ++I +S++GS +G+T +L
Sbjct: 15 ARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVT-----------AL 63
Query: 877 PLNISRLPHFTAYIDGKYMKYSKAGCSVKEKDMRSFVPSF----EWLRTGDRLGLKKTSD 932
++ P + G + +GCSV +D RS + + + L GDR+G+++T
Sbjct: 64 DPSVLDFPSSATGLKGG--SWVVSGCSVL-RDGRSVLEEYGQDLDQLGEGDRVGVERTVA 120
Query: 933 FKVLVYYNSELLDVAFEKVPDKVFAVMELCGPVTKIHTISMAGGVAASNTTTIPNKSIPK 992
++ ++ N VA +P +V+AV++L G T+I + G S T IP +
Sbjct: 121 GELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPPEPGF--SPPTPIPTPPLEP 178
Query: 993 RQPQLNEDGTICPVSTSANMDRETDNQFGIGNEPSTSNTESNKNVRENLIASIDTANTES 1052
P +ED + TSA D F + + T N N A+++ + S
Sbjct: 179 LAP--SEDSALAEQGTSA------DEAFMVSPAQARPETFPNSLESHNDFANMELSEVVS 230
Query: 1053 NTMST----------LTVVPT-----ETRRRRNPL-----PYTFHYVHGKNIKLCSSDTV 1092
NT+ + L+ P + +P+ FH G IKL +++
Sbjct: 231 NTILSAYNGGLLNVNLSSPPAGEGLGSSGAATSPILTSNDALLFHEKCGTLIKLSNNNKT 290
Query: 1093 AVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGIGAVGHLA-SEELPPTA 1148
A R + +G+ + ++PLR F RIDK++ W GS+ IG H S E P T
Sbjct: 291 AERRRPLDEFNNGVVMTNRPLRGNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATM 350
Query: 1149 MQLEPPVWVITSDLIYDNGDYIKTKR-GAPLDNLTEQSVLTIHFRLNSDIAVDIDSEPLG 1207
L+ +++ I NG + + LD L E + + + NS + I+ G
Sbjct: 351 TNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQG 410
Query: 1208 VIGAVSRNACHVFPLIDLYG 1227
V A V+ ++DLYG
Sbjct: 411 V--ATPLTPPVVYGVVDLYG 428
Score = 72.9 bits (171), Expect = 8e-12
Identities = 48/164 (29%), Positives = 78/164 (47%), Gaps = 7/164 (4%)
Query: 1072 LPYTFHYV--HGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLG 1129
+P T ++ HGKNI L + + A R + Y G+ +I+QPL + RID + W
Sbjct: 1080 IPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTS 1139
Query: 1130 SVGIGAVGHLASEEL--PPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVL 1187
S+ +G + A E L P +A L+ W++ ++ NG I K G LD E ++L
Sbjct: 1140 SLVLGVI-TCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTIL 1198
Query: 1188 TIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
+ + + + ++ GV CH L+DLYG+ Q
Sbjct: 1199 GLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHA--LVDLYGQCEQ 1240
Score = 62.9 bits (146), Expect = 9e-09
Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Query: 1076 FHYVHGKNIKLCSSDTVAVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVG 1132
FH +HG N + + A+R S + D + I ++ LR G F I K++ W GS+
Sbjct: 673 FHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIE 732
Query: 1133 IGAVGHLASE-ELPPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHF 1191
G + E P T ++ W+++ I +G+ ++ G LD L + + +
Sbjct: 733 AGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMR 792
Query: 1192 RLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
D+ I+ + G A S V+ ++DLYG+ Q
Sbjct: 793 TAKGDLHYFINGQDQG--AACSGLPPEVYAVVDLYGQCVQ 830
Score = 62.5 bits (145), Expect = 1e-08
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Query: 1076 FHYVHGKNIKLCSSDTVAVR---TSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVG 1132
FH G+ + A+R T + G+ + S+ LR G F+ RIDK++ W GS+
Sbjct: 477 FHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIE 536
Query: 1133 IGAVGH-LASEELPPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHF 1191
IG H A +LP T L W++T + + NG I + G LD L + +
Sbjct: 537 IGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDAVGVVR 596
Query: 1192 RLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
R + + ++ G A V+ ++DLYG+ Q
Sbjct: 597 REDGTLHFFVNGMTQG--PAAWNVPPGVYAVVDLYGQAAQ 634
Score = 59.7 bits (138), Expect = 8e-08
Identities = 45/167 (26%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 1074 YTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGI 1133
+ FH GKN+ L T AVR +GY GL ++ LR F +++++ W GS+ +
Sbjct: 866 HRFHSTCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 925
Query: 1134 G----AVGHL------ASEELPPTAMQLE-PPVWVITSDLIYDNGDYIKTKRGAPLDNLT 1182
G A G + LPP+ +L W+++S + +G + G L+ L
Sbjct: 926 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLG 985
Query: 1183 EQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRV 1229
S + + + + + +D E +G A + A +V+ ++DLYG V
Sbjct: 986 VGSRVGVRRGADDTMHILVDGEDMG--PAATGIAKNVWAVLDLYGPV 1030
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 1099 YKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGIGAVGHLASE-ELPPTAMQLEPPVWV 1157
+ GL + +PLR G F RID+ + W GS+ IG S + P +A L+ WV
Sbjct: 24 FNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWV 83
Query: 1158 ITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRNAC 1217
++ + +G + + G LD L E + + + ++ + ++ GV A +
Sbjct: 84 VSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGV--AATGLPP 141
Query: 1218 HVFPLIDLYGRVTQ 1231
V+ ++DLYG+ TQ
Sbjct: 142 RVWAVVDLYGKCTQ 155
>BC007227-1|AAH07227.1| 530|Homo sapiens KIAA1787 protein protein.
Length = 530
Score = 229 bits (561), Expect = 5e-59
Identities = 164/546 (30%), Positives = 266/546 (48%), Gaps = 44/546 (8%)
Query: 245 TAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATIRFPST 304
TA R ++N+ +V+++R L D ELFEI I ++VD+WSGS+E GVT P + FP+T
Sbjct: 1 TALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNT 60
Query: 305 MTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFINGVDQ 364
MT++D T M+SG ++ +G+ YG +LD L +G++R + G+LHYFING DQ
Sbjct: 61 MTDIDYDTWMLSGTAIMQDGNTMRNNYG-CDLDALGTGARIGMMRTAKGDLHYFINGQDQ 119
Query: 365 GVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPMNAIDIAEPRRFRPAID 424
G A + P+V+ VVDLYG V+VSI + MD++ + A + + P +
Sbjct: 120 GAACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNS---LATSNTATEKSFP--LHSPVA 174
Query: 425 EDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKW 484
+ FH+ NV + DG A R + +G+V + + LR E+F+V+++ + KW
Sbjct: 175 GVAHRFHSTCGKNVTLEEDGTRAVRAAGYA---HGLVFSTKELRAEEVFEVKVEELDEKW 231
Query: 485 AGSIEIGVTQHTASEF---------EFPFRMSNAKS-GTWAITGEDVIRDGTIIIPQYVR 534
AGS+ +G+T E P + ++ TW ++ +V RDG + Y R
Sbjct: 232 AGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGR 291
Query: 535 NLNRLVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQATIVD-- 592
NL RL G VGV R +H V+G D GPAA I ++V+ ++DLYG V +IV
Sbjct: 292 NLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSST 351
Query: 593 -IYLXXXXXXXXXXXXTESNATVNPEMCFHRVHGRN------------ARLSRNRLTAS- 638
+ T S + E H + G+N +N L ++
Sbjct: 352 RLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNG 411
Query: 639 --RATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEXXXXX 696
AT + +N ++ ++PL + ++RID + W SL +GV P+ L
Sbjct: 412 NRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASA 471
Query: 697 XXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADRSLHYYL 756
L ++L G + +G + + +LDT G+ +G+ + LH ++
Sbjct: 472 CA-------LKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHV 524
Query: 757 DGMDMG 762
+ G
Sbjct: 525 NAWTRG 530
Score = 198 bits (483), Expect = 1e-49
Identities = 110/343 (32%), Positives = 184/343 (53%), Gaps = 11/343 (3%)
Query: 446 TAHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFR 505
TA R N FN+ +V++NR LR ELF++ + ++ +W+GSIE GVT + EFP
Sbjct: 1 TALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNT 60
Query: 506 MSNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQG 565
M++ TW ++G +++DG + Y +L+ L G +G+MR G LH+++NG DQG
Sbjct: 61 MTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQG 120
Query: 566 PAAFNIPEHVFGIIDLYGRVAQATIVDIYLXXXXXXXXXXXXTESNATVNPEMC-----F 620
A +P V+ ++DLYG+ Q +I + TE + ++ + F
Sbjct: 121 AACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNSLATSNTATEKSFPLHSPVAGVAHRF 180
Query: 621 HRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEI 680
H G+N L + A RA Y+ ++FS++ LR ++FE++++++ + W GSL +
Sbjct: 181 HSTCGKNVTLEEDGTRAVRAAGYAH---GLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 237
Query: 681 GVTAIRPDDLEXXXXXXXXXX--XXXDLNW-DTYILSGAAMMKDGECVRSGYPLDLDTLT 737
G+T + P ++ +L T+++S + +DG R Y +L+ L
Sbjct: 238 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLG 297
Query: 738 VGSRVGMMWHADRSLHYYLDGMDMGKAWYVPHLNIYAVVDLYG 780
VGSRVG+ AD ++H +DG DMG A N++AV+DLYG
Sbjct: 298 VGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYG 340
Score = 183 bits (445), Expect = 5e-45
Identities = 124/360 (34%), Positives = 184/360 (51%), Gaps = 34/360 (9%)
Query: 636 TASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRPDDLEXXXX 695
TA R SEFNDA++ S+R LR+ ++FE+ I KMVD W GS+E GVTAIRP+DLE
Sbjct: 1 TALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNT 60
Query: 696 XXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVGMMWHADRSLHYY 755
D+++DT++LSG A+M+DG +R+ Y DLD L G+R+GMM A LHY+
Sbjct: 61 MT-------DIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYF 113
Query: 756 LDGMDMGKAWYVPHLNIYAVVDLYGQCTQTCRT--YGSMVN------------------V 795
++G D G A +YAVVDLYGQC Q T G M N V
Sbjct: 114 INGQDQGAACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNSLATSNTATEKSFPLHSPV 173
Query: 796 FGIFRSFSEYCGENVCMMHGCSVARRLTPDPTYALVFSSAHLAVGEMFEIKIVECKSSYA 855
G+ F CG+NV + + A R + LVFS+ L E+FE+K+ E +A
Sbjct: 174 AGVAHRFHSTCGKNVTLEEDGTRAVR-AAGYAHGLVFSTKELRAEEVFEVKVEELDEKWA 232
Query: 856 GSFRMGITDVNILNAHVNRSLPLNISRLPHFTAYIDGKYMKYSKAGCSVKEK---DMRSF 912
GS R+G+T + + LP + K + + C V+ ++
Sbjct: 233 GSLRLGLT--TLAPGEMGPGAGGGGPGLPPSLPELRTK-TTWMVSSCEVRRDGHLQRMNY 289
Query: 913 VPSFEWLRTGDRLGLKKTSDFKVLVYYNSELLDVAFEKVPDKVFAVMELCGPVTKIHTIS 972
+ E L G R+G+++ +D + + + E + A + V+AV++L GPV + +S
Sbjct: 290 GRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVS 349
Score = 146 bits (354), Expect = 6e-34
Identities = 64/141 (45%), Positives = 97/141 (68%)
Query: 26 EFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIGVTTLDPEFMELPATATKLRNTAW 85
EFN +++S + D +FE+ I + V+ W+GS+E GVT + PE +E P T T + W
Sbjct: 10 EFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTW 69
Query: 86 IMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTSKAELTFYINGRCLGVAAKDLPPR 145
++SG++I++DG T+ N+YG +LD L G +G+MRT+K +L ++ING+ G A LPP
Sbjct: 70 MLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPE 129
Query: 146 LFAVIDLYGQCVQVSISQVNG 166
++AV+DLYGQCVQVSI+ G
Sbjct: 130 VYAVVDLYGQCVQVSITNATG 150
Score = 145 bits (351), Expect = 1e-33
Identities = 105/359 (29%), Positives = 164/359 (45%), Gaps = 28/359 (7%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH CG V L + A RA Y +G+V + + L E+FE++++ L +KW+GS+
Sbjct: 179 RFHSTCGKNVTLEEDGTRAVRAA---GYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSL 235
Query: 288 EVGVTTHNPATIR---------FPSTMTNMDSGTI-MMSGCKVLLNGHGTCMEYGNFNLD 337
+G+TT P + P ++ + + T M+S C+V +GH M YG NL+
Sbjct: 236 RLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGR-NLE 294
Query: 338 DLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDM 397
L VG+ R ++ +H ++G D G A + VW V+DLYG VSIV
Sbjct: 295 RLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLE 354
Query: 398 DSNIQHIPQPMNAI-------DIAEPR----RFRPAIDEDSLLFHTLRDSNVIIINDGKT 446
+S P P + D E + I +L F N+++ N +T
Sbjct: 355 ESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNGNRT 414
Query: 447 AHRPNAFEFFNNGVVMTNRTLRTNELFQVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRM 506
A R + +N G+V+ N+ L L QVR+D + +W S+ +GV FP
Sbjct: 415 ATRVAS---YNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASA 471
Query: 507 SNAKSGTWAITGEDVIRDGTIIIPQYVRNLNRLVEGDTVGVMRKDMGILHFYVNGIDQG 565
K W + G V +G I ++ NL+ EG +G+ G LH +VN +G
Sbjct: 472 CALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNAWTRG 530
Score = 144 bits (348), Expect = 3e-33
Identities = 111/375 (29%), Positives = 177/375 (47%), Gaps = 34/375 (9%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FH CG VTL D + A+R + HGL+ S + + + +FEV ++ W GSL +
Sbjct: 179 RFHSTCGKNVTLEEDGTRAVRA-AGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 237
Query: 62 GVTTLDPEFME---------LPATATKLRN-TAWIMSGSSIVKDGVTLVNSYGPELDTLR 111
G+TTL P M LP + +LR T W++S + +DG +YG L+ L
Sbjct: 238 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLG 297
Query: 112 EGDCLGVMRTSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAM 171
G +GV R + + ++G +G AA + ++AV+DLYG VSI L +
Sbjct: 298 VGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEES- 356
Query: 172 ELCLVQAEDDPN-NDDTLTSSEIDVAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFH 230
+ P+ + DT + E D G ++ + G + + L H
Sbjct: 357 -----EGTQPPSPSSDTGSEGEEDDEG---------EEHGLGGQNEVGIIPTTLEFLENH 402
Query: 231 PRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVG 290
G + LS N+TA R + YN G+V+ ++PL L ++RID L +W+ S+ +G
Sbjct: 403 ---GKNILLSNGNRTATR---VASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLG 456
Query: 291 VTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRK 350
V T P + FP++ + ++ G V NG C ++G NLD E +GL
Sbjct: 457 VITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGP-NLDTCPEGTILGLRLD 515
Query: 351 SNGELHYFINGVDQG 365
S+G LH +N +G
Sbjct: 516 SSGGLHLHVNAWTRG 530
Score = 86.6 bits (205), Expect = 6e-16
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
++F G + L N N TA R +N G+++ +P+ ++ +V ID W SL
Sbjct: 396 LEFLENHGKNILLSNGNRTATR-VASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLV 454
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
+GV T PE + PA+A L+ AW++ G + +G+ + +GP LDT EG LG+
Sbjct: 455 LGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRL 514
Query: 121 TSKAELTFYIN 131
S L ++N
Sbjct: 515 DSSGGLHLHVN 525
Score = 61.3 bits (142), Expect = 3e-08
Identities = 41/128 (32%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 1072 LPYTFHYV--HGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLG 1129
+P T ++ HGKNI L + + A R + Y G+ +I+QPL + RID + W
Sbjct: 392 IPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTS 451
Query: 1130 SVGIGAVGHLASEEL--PPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVL 1187
S+ +G + A E L P +A L+ W++ ++ NG I K G LD E ++L
Sbjct: 452 SLVLGVI-TCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTIL 510
Query: 1188 TIHFRLNS 1195
+ RL+S
Sbjct: 511 GL--RLDS 516
Score = 59.3 bits (137), Expect = 1e-07
Identities = 45/167 (26%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 1074 YTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGI 1133
+ FH GKN+ L T AVR +GY GL ++ LR F +++++ W GS+ +
Sbjct: 178 HRFHSTCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRL 237
Query: 1134 G----AVGHL------ASEELPPTAMQLE-PPVWVITSDLIYDNGDYIKTKRGAPLDNLT 1182
G A G + LPP+ +L W+++S + +G + G L+ L
Sbjct: 238 GLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLG 297
Query: 1183 EQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRV 1229
S + + + + + +D E +G A + A +V+ ++DLYG V
Sbjct: 298 VGSRVGVRRGADDTMHILVDGEDMG--PAATGIAKNVWAVLDLYGPV 342
Score = 52.8 bits (121), Expect = 1e-05
Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
Query: 1097 SGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLGSVGIGAVGHLASE-ELPPTAMQLEPPV 1155
S + D + I ++ LR G F I K++ W GS+ G + E P T ++
Sbjct: 9 SEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDT 68
Query: 1156 WVITSDLIYDNGDYIKTKRGAPLDNLTEQSVLTIHFRLNSDIAVDIDSEPLGVIGAVSRN 1215
W+++ I +G+ ++ G LD L + + + D+ I+ + G A S
Sbjct: 69 WMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQG--AACSGL 126
Query: 1216 ACHVFPLIDLYGRVTQ 1231
V+ ++DLYG+ Q
Sbjct: 127 PPEVYAVVDLYGQCVQ 142
Score = 47.6 bits (108), Expect = 4e-04
Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 22/174 (12%)
Query: 829 ALVFSSAHLAVGEMFEIKIVECKSSYAGSFRMGITDVNILNAHVNRSLPLNISRLPHFTA 888
A+V S+ L GE+FEI I + ++GS G+T + P ++ P+
Sbjct: 14 AIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIR----------PEDLE-FPNTMT 62
Query: 889 YIDGKYMKYSKAGCSVKE--KDMRS-FVPSFEWLRTGDRLGLKKTSDFKVLVYYNSELLD 945
ID Y + +G ++ + MR+ + + L TG R+G+ +T+ + + N +
Sbjct: 63 DID--YDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQG 120
Query: 946 VAFEKVPDKVFAVMELCGPVTKIHTISMAG----GVAASNTTTIPNKSIPKRQP 995
A +P +V+AV++L G ++ + G +A SNT T KS P P
Sbjct: 121 AACSGLPPEVYAVVDLYGQCVQVSITNATGPMDNSLATSNTAT--EKSFPLHSP 172
>BC073134-1|AAH73134.1| 505|Homo sapiens KIAA1787 protein protein.
Length = 505
Score = 117 bits (282), Expect = 3e-25
Identities = 58/161 (36%), Positives = 88/161 (54%), Gaps = 1/161 (0%)
Query: 1 MKFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLE 60
++F G + L N N TA R +N G+++ +P+ ++ +V ID W SL
Sbjct: 75 LEFLENHGKNILLSNGNRTATR-VASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLV 133
Query: 61 IGVTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMR 120
+GV T PE + PA+A L+ AW++ G + +G+ + +GP LDT EG LG+
Sbjct: 134 LGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRL 193
Query: 121 TSKAELTFYINGRCLGVAAKDLPPRLFAVIDLYGQCVQVSI 161
S L ++NG GVA D+P A++DLYGQC QV+I
Sbjct: 194 DSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTI 234
Score = 108 bits (259), Expect = 2e-22
Identities = 72/239 (30%), Positives = 107/239 (44%), Gaps = 14/239 (5%)
Query: 365 GVATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQHIPQPMNAI-------DIAEPR 417
G A + VW V+DLYG VSIV +S P P + D E
Sbjct: 1 GPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEH 60
Query: 418 RF----RPAIDEDSLLFHTLRDSNVIIINDGKTAHRPNAFEFFNNGVVMTNRTLRTNELF 473
I +L F N+++ N +TA R ++ N G+V+ N+ L L
Sbjct: 61 GLGGQNEVGIIPTTLEFLENHGKNILLSNGNRTATRVASY---NQGIVVINQPLVPQLLV 117
Query: 474 QVRLDLIIPKWAGSIEIGVTQHTASEFEFPFRMSNAKSGTWAITGEDVIRDGTIIIPQYV 533
QVR+D + +W S+ +GV FP K W + G V +G I ++
Sbjct: 118 QVRIDFLNRQWTSSLVLGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFG 177
Query: 534 RNLNRLVEGDTVGVMRKDMGILHFYVNGIDQGPAAFNIPEHVFGIIDLYGRVAQATIVD 592
NL+ EG +G+ G LH +VNG+DQG A ++P+ ++DLYG+ Q TIV+
Sbjct: 178 PNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVN 236
Score = 106 bits (254), Expect = 7e-22
Identities = 82/259 (31%), Positives = 123/259 (47%), Gaps = 23/259 (8%)
Query: 136 GVAAKDLPPRLFAVIDLYGQCVQVSISQVNGLRTAMELCLVQAEDDPN-NDDTLTSSEID 194
G AA + ++AV+DLYG VSI L + + P+ + DT + E D
Sbjct: 1 GPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEES------EGTQPPSPSSDTGSEGEED 54
Query: 195 VAGLPSAPFPKETQNIYVPMSSEGACSSAQDHLRFHPRCGILVKLSGNNKTAERARPLDD 254
G ++ + G + + L H G + LS N+TA R
Sbjct: 55 DEG---------EEHGLGGQNEVGIIPTTLEFLENH---GKNILLSNGNRTATRVA---S 99
Query: 255 YNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSVEVGVTTHNPATIRFPSTMTNMDSGTIM 314
YN G+V+ ++PL L ++RID L +W+ S+ +GV T P + FP++ + +
Sbjct: 100 YNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASACALKRAAWL 159
Query: 315 MSGCKVLLNGHGTCMEYGNFNLDDLREAETVGLLRKSNGELHYFINGVDQGVATDKVEPQ 374
+ G V NG C ++G NLD E +GL S+G LH +NGVDQGVA V
Sbjct: 160 LRGRGVFHNGLKICEKFGP-NLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDVPQP 218
Query: 375 VWGVVDLYGMTVKVSIVDP 393
+VDLYG +V+IV+P
Sbjct: 219 CHALVDLYGQCEQVTIVNP 237
Score = 72.9 bits (171), Expect = 8e-12
Identities = 48/164 (29%), Positives = 78/164 (47%), Gaps = 7/164 (4%)
Query: 1072 LPYTFHYV--HGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDWLG 1129
+P T ++ HGKNI L + + A R + Y G+ +I+QPL + RID + W
Sbjct: 71 IPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTS 130
Query: 1130 SVGIGAVGHLASEEL--PPTAMQLEPPVWVITSDLIYDNGDYIKTKRGAPLDNLTEQSVL 1187
S+ +G + A E L P +A L+ W++ ++ NG I K G LD E ++L
Sbjct: 131 SLVLGVI-TCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTIL 189
Query: 1188 TIHFRLNSDIAVDIDSEPLGVIGAVSRNACHVFPLIDLYGRVTQ 1231
+ + + + ++ GV CH L+DLYG+ Q
Sbjct: 190 GLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHA--LVDLYGQCEQ 231
Score = 66.5 bits (155), Expect = 7e-10
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 10/161 (6%)
Query: 624 HGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVT 683
HG+N LS TA+R Y N ++ ++PL + ++RID + W SL +GV
Sbjct: 81 HGKNILLSNGNRTATRVASY---NQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVI 137
Query: 684 AIRPDDLEXXXXXXXXXXXXXDLNWDTYILSGAAMMKDGECVRSGYPLDLDTLTVGSRVG 743
P+ L L ++L G + +G + + +LDT G+ +G
Sbjct: 138 TCAPERLNFPASACA-------LKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILG 190
Query: 744 MMWHADRSLHYYLDGMDMGKAWYVPHLNIYAVVDLYGQCTQ 784
+ + LH +++G+D G A +A+VDLYGQC Q
Sbjct: 191 LRLDSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQ 231
>BC107485-1|AAI07486.1| 285|Homo sapiens neuralized homolog 2
(Drosophila) protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>BC105935-1|AAI05936.1| 285|Homo sapiens neuralized homolog 2
(Drosophila) protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>BC074737-1|AAH74737.1| 285|Homo sapiens neuralized homolog 2
(Drosophila) protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>AL008726-12|CAC36018.1| 285|Homo sapiens neuralized homolog 2
(Drosophila) protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>AK054821-1|BAB70810.1| 285|Homo sapiens nyltransferase. protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>AJ295985-1|CAC82498.1| 285|Homo sapiens hypothetical protein
protein.
Length = 285
Score = 49.6 bits (113), Expect = 9e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 616 PEMCFHRVHGRNARLSRNRLTASRATVYSEFNDAVLFSSRPLRECDMFELRIDKMVDCWI 675
P FHRVHG N R+ + +RAT F V FS PL +F + I++ W
Sbjct: 22 PPTRFHRVHGANIRVDPS---GTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 676 GSLEIGVTAIRPDDL 690
G L +G+TA+ P L
Sbjct: 79 GHLRLGLTALDPASL 93
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%)
Query: 1068 RRNPLPYTFHYVHGKNIKLCSSDTVAVRTSGYKDGLAIISQPLRRGHSFRFRIDKVMMDW 1127
R P P FH VHG NI++ S T A R + G+ +PL G F I++ + W
Sbjct: 18 RPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW 77
Query: 1128 LGSVGIG 1134
G + +G
Sbjct: 78 CGHLRLG 84
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 2 KFHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEI 61
+FHR G + + + + T F HG+ S EP++ +F V I+ K W G L +
Sbjct: 25 RFHRVHGANIRV-DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
Query: 62 GVTTLDP 68
G+T LDP
Sbjct: 84 GLTALDP 90
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 228 RFHPRCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSGSV 287
RFH G +++ + + RA ++ + +GV + PL ++F + I+ W G +
Sbjct: 25 RFHRVHGANIRV---DPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 288 EVGVTTHNPATI 299
+G+T +PA++
Sbjct: 82 RLGLTALDPASL 93
>BC026336-1|AAH26336.1| 574|Homo sapiens neuralized homolog
(Drosophila) protein.
Length = 574
Score = 49.2 bits (112), Expect = 1e-04
Identities = 94/425 (22%), Positives = 168/425 (39%), Gaps = 51/425 (12%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIG 62
FH L++ + A++ F + + S P+ + I +K W+G+L +G
Sbjct: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
Query: 63 VTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTS 122
T+ DP + P + K ++S S + PE + EG+ +
Sbjct: 125 FTSKDPSRIH-PDSLPKYACPD-LVSQSGFWAKAL-------PE-EFANEGNIIAFWVDK 174
Query: 123 KAELTFYINGRCLGV---AAKDLPPRLFAVIDLYG--QCVQVSISQV---NGLR----TA 170
K + IN + + + P L+A++D+YG + VQ+ S++ + LR TA
Sbjct: 175 KGRVFHRINDSAVMLFFSGVRTADP-LWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTA 233
Query: 171 MELCLVQAE-DDPNNDDTLTSSEI------DVAGLPSAPFPKETQNIYVPMSSEGACSSA 223
+ ++ E DD +L + + A S P P+ + N S +
Sbjct: 234 LRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAASCPIPQNSLN---SQHSRALPAQL 290
Query: 224 QDHLRFHP-RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDK 282
LRFH R G V++ A D+ +V T RP+ E +++ R
Sbjct: 291 DGDLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGA 348
Query: 283 WSGSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREA 342
G++ GVTT +P T+R P+ + + C G L
Sbjct: 349 RPGALSFGVTTCDPGTLR-PADLPFSPEALVDRK------EFWAVCRVPG-----PLHSG 396
Query: 343 ETVGLLRKSNGELHYFINGVDQG--VATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSN 400
+ +GL+ ++GELH NG G + D +P +W + L+G ++ I+ +
Sbjct: 397 DILGLVVNADGELHLSHNGAAAGMQLCVDASQP-LWMLFGLHGTITQIRILGSTILAERG 455
Query: 401 IQHIP 405
I +P
Sbjct: 456 IPSLP 460
Score = 37.1 bits (82), Expect = 0.52
Identities = 42/165 (25%), Positives = 67/165 (40%), Gaps = 17/165 (10%)
Query: 1 MKFHR-RCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
++FH R G V +L++ + A L+ ++ P+ V + R G+L
Sbjct: 294 LRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGAL 353
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIV--KDGVTLVNSYGPELDTLREGDCLG 117
GVTT DP + PA S ++V K+ + GP L GD LG
Sbjct: 354 SFGVTTCDPGTLR-PADLP--------FSPEALVDRKEFWAVCRVPGP----LHSGDILG 400
Query: 118 VMRTSKAELTFYINGRCLGV-AAKDLPPRLFAVIDLYGQCVQVSI 161
++ + EL NG G+ D L+ + L+G Q+ I
Sbjct: 401 LVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRI 445
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 87 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 130
Score = 35.9 bits (79), Expect = 1.2
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
Query: 286 SVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETV 345
++ +G T+ +P+ I S + SG E+ N E +
Sbjct: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG----FWAKALPEEFAN-------EGNII 168
Query: 346 GLLRKSNGELHYFIN--GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVD 392
G + + IN V + + +W +VD+YG+T V ++D
Sbjct: 169 AFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLD 217
>U87864-1|AAC17474.1| 574|Homo sapiens neuralized homolog protein.
Length = 574
Score = 48.0 bits (109), Expect = 3e-04
Identities = 95/423 (22%), Positives = 167/423 (39%), Gaps = 47/423 (11%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIG 62
FH L++ + A++ F + + S P+ + I +K W+G+L +G
Sbjct: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
Query: 63 VTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTS 122
T+ DP + P + K ++S S + PE + EG+ +
Sbjct: 125 FTSKDPSRIH-PDSLPKYACPD-LVSQSGFWAKAL-------PE-EFANEGNIIAFWVDK 174
Query: 123 KAELTFYINGRCLGV---AAKDLPPRLFAVIDLYG--QCVQVSISQV---NGLR----TA 170
K + IN + + + P L+A++D+YG + VQ+ S++ + LR TA
Sbjct: 175 KGRVFHRINDSAVMLFFSGVRTADP-LWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTA 233
Query: 171 MELCLVQAE-DDPNNDDTLTSSEIDVA----GLPSAPFPKETQNIYVPMSSEGACSSAQD 225
+ ++ E DD +L + A P+A P QN S +
Sbjct: 234 LRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIP-QNSLNSQHSRALPAQLDG 292
Query: 226 HLRFHP-RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWS 284
LRFH R G V++ A D+ +V T RP+ E +++ R
Sbjct: 293 DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARP 350
Query: 285 GSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAET 344
G++ GVTT +P T+R P+ + + C G L +
Sbjct: 351 GALSFGVTTCDPGTLR-PADLPFSPEALVDRK------EFWAVCRVPG-----PLHSGDI 398
Query: 345 VGLLRKSNGELHYFINGVDQG--VATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQ 402
+GL+ ++GELH NG G + D +P +W + L+G ++ I+ + I
Sbjct: 399 LGLVVNADGELHLSHNGAAAGMQLCVDASQP-LWMLFGLHGTITQIRILGSTILAERGIP 457
Query: 403 HIP 405
+P
Sbjct: 458 SLP 460
Score = 37.1 bits (82), Expect = 0.52
Identities = 42/165 (25%), Positives = 67/165 (40%), Gaps = 17/165 (10%)
Query: 1 MKFHR-RCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
++FH R G V +L++ + A L+ ++ P+ V + R G+L
Sbjct: 294 LRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGAL 353
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIV--KDGVTLVNSYGPELDTLREGDCLG 117
GVTT DP + PA S ++V K+ + GP L GD LG
Sbjct: 354 SFGVTTCDPGTLR-PADLP--------FSPEALVDRKEFWAVCRVPGP----LHSGDILG 400
Query: 118 VMRTSKAELTFYINGRCLGV-AAKDLPPRLFAVIDLYGQCVQVSI 161
++ + EL NG G+ D L+ + L+G Q+ I
Sbjct: 401 LVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRI 445
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 87 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 130
Score = 35.9 bits (79), Expect = 1.2
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
Query: 286 SVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETV 345
++ +G T+ +P+ I S + SG E+ N E +
Sbjct: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG----FWAKALPEEFAN-------EGNII 168
Query: 346 GLLRKSNGELHYFIN--GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVD 392
G + + IN V + + +W +VD+YG+T V ++D
Sbjct: 169 AFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLD 217
>AL139339-4|CAH71486.1| 574|Homo sapiens neuralized homolog
(Drosophila) protein.
Length = 574
Score = 48.0 bits (109), Expect = 3e-04
Identities = 95/423 (22%), Positives = 167/423 (39%), Gaps = 47/423 (11%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIG 62
FH L++ + A++ F + + S P+ + I +K W+G+L +G
Sbjct: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
Query: 63 VTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTS 122
T+ DP + P + K ++S S + PE + EG+ +
Sbjct: 125 FTSKDPSRIH-PDSLPKYACPD-LVSQSGFWAKAL-------PE-EFANEGNIIAFWVDK 174
Query: 123 KAELTFYINGRCLGV---AAKDLPPRLFAVIDLYG--QCVQVSISQV---NGLR----TA 170
K + IN + + + P L+A++D+YG + VQ+ S++ + LR TA
Sbjct: 175 KGRVFHRINDSAVMLFFSGVRTADP-LWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTA 233
Query: 171 MELCLVQAE-DDPNNDDTLTSSEIDVA----GLPSAPFPKETQNIYVPMSSEGACSSAQD 225
+ ++ E DD +L + A P+A P QN S +
Sbjct: 234 LRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIP-QNSLNSQHSRALPAQLDG 292
Query: 226 HLRFHP-RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWS 284
LRFH R G V++ A D+ +V T RP+ E +++ R
Sbjct: 293 DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARP 350
Query: 285 GSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAET 344
G++ GVTT +P T+R P+ + + C G L +
Sbjct: 351 GALSFGVTTCDPGTLR-PADLPFSPEALVDRK------EFWAVCRVPG-----PLHSGDI 398
Query: 345 VGLLRKSNGELHYFINGVDQG--VATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQ 402
+GL+ ++GELH NG G + D +P +W + L+G ++ I+ + I
Sbjct: 399 LGLVVNADGELHLSHNGAAAGMQLCVDASQP-LWMLFGLHGTITQIRILGSTILAERGIP 457
Query: 403 HIP 405
+P
Sbjct: 458 SLP 460
Score = 37.1 bits (82), Expect = 0.52
Identities = 42/165 (25%), Positives = 67/165 (40%), Gaps = 17/165 (10%)
Query: 1 MKFHR-RCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
++FH R G V +L++ + A L+ ++ P+ V + R G+L
Sbjct: 294 LRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGAL 353
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIV--KDGVTLVNSYGPELDTLREGDCLG 117
GVTT DP + PA S ++V K+ + GP L GD LG
Sbjct: 354 SFGVTTCDPGTLR-PADLP--------FSPEALVDRKEFWAVCRVPGP----LHSGDILG 400
Query: 118 VMRTSKAELTFYINGRCLGV-AAKDLPPRLFAVIDLYGQCVQVSI 161
++ + EL NG G+ D L+ + L+G Q+ I
Sbjct: 401 LVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRI 445
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 87 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 130
Score = 35.9 bits (79), Expect = 1.2
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
Query: 286 SVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETV 345
++ +G T+ +P+ I S + SG E+ N E +
Sbjct: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG----FWAKALPEEFAN-------EGNII 168
Query: 346 GLLRKSNGELHYFIN--GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVD 392
G + + IN V + + +W +VD+YG+T V ++D
Sbjct: 169 AFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLD 217
>AL121929-3|CAI13960.1| 574|Homo sapiens neuralized homolog
(Drosophila) protein.
Length = 574
Score = 48.0 bits (109), Expect = 3e-04
Identities = 95/423 (22%), Positives = 167/423 (39%), Gaps = 47/423 (11%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIG 62
FH L++ + A++ F + + S P+ + I +K W+G+L +G
Sbjct: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
Query: 63 VTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTS 122
T+ DP + P + K ++S S + PE + EG+ +
Sbjct: 125 FTSKDPSRIH-PDSLPKYACPD-LVSQSGFWAKAL-------PE-EFANEGNIIAFWVDK 174
Query: 123 KAELTFYINGRCLGV---AAKDLPPRLFAVIDLYG--QCVQVSISQV---NGLR----TA 170
K + IN + + + P L+A++D+YG + VQ+ S++ + LR TA
Sbjct: 175 KGRVFHRINDSAVMLFFSGVRTADP-LWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTA 233
Query: 171 MELCLVQAE-DDPNNDDTLTSSEIDVA----GLPSAPFPKETQNIYVPMSSEGACSSAQD 225
+ ++ E DD +L + A P+A P QN S +
Sbjct: 234 LRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIP-QNSLNSQHSRALPAQLDG 292
Query: 226 HLRFHP-RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWS 284
LRFH R G V++ A D+ +V T RP+ E +++ R
Sbjct: 293 DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARP 350
Query: 285 GSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAET 344
G++ GVTT +P T+R P+ + + C G L +
Sbjct: 351 GALSFGVTTCDPGTLR-PADLPFSPEALVDRK------EFWAVCRVPG-----PLHSGDI 398
Query: 345 VGLLRKSNGELHYFINGVDQG--VATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQ 402
+GL+ ++GELH NG G + D +P +W + L+G ++ I+ + I
Sbjct: 399 LGLVVNADGELHLSHNGAAAGMQLCVDASQP-LWMLFGLHGTITQIRILGSTILAERGIP 457
Query: 403 HIP 405
+P
Sbjct: 458 SLP 460
Score = 37.1 bits (82), Expect = 0.52
Identities = 42/165 (25%), Positives = 67/165 (40%), Gaps = 17/165 (10%)
Query: 1 MKFHR-RCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
++FH R G V +L++ + A L+ ++ P+ V + R G+L
Sbjct: 294 LRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGAL 353
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIV--KDGVTLVNSYGPELDTLREGDCLG 117
GVTT DP + PA S ++V K+ + GP L GD LG
Sbjct: 354 SFGVTTCDPGTLR-PADLP--------FSPEALVDRKEFWAVCRVPGP----LHSGDILG 400
Query: 118 VMRTSKAELTFYINGRCLGV-AAKDLPPRLFAVIDLYGQCVQVSI 161
++ + EL NG G+ D L+ + L+G Q+ I
Sbjct: 401 LVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRI 445
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 87 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 130
Score = 35.9 bits (79), Expect = 1.2
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
Query: 286 SVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETV 345
++ +G T+ +P+ I S + SG E+ N E +
Sbjct: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG----FWAKALPEEFAN-------EGNII 168
Query: 346 GLLRKSNGELHYFIN--GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVD 392
G + + IN V + + +W +VD+YG+T V ++D
Sbjct: 169 AFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLD 217
>AF029729-1|AAD01887.1| 574|Homo sapiens neuralized protein.
Length = 574
Score = 48.0 bits (109), Expect = 3e-04
Identities = 95/423 (22%), Positives = 167/423 (39%), Gaps = 47/423 (11%)
Query: 3 FHRRCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSLEIG 62
FH L++ + A++ F + + S P+ + I +K W+G+L +G
Sbjct: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
Query: 63 VTTLDPEFMELPATATKLRNTAWIMSGSSIVKDGVTLVNSYGPELDTLREGDCLGVMRTS 122
T+ DP + P + K ++S S + PE + EG+ +
Sbjct: 125 FTSKDPSRIH-PDSLPKYACPD-LVSQSGFWAKAL-------PE-EFANEGNIIAFWVDK 174
Query: 123 KAELTFYINGRCLGV---AAKDLPPRLFAVIDLYG--QCVQVSISQV---NGLR----TA 170
K + IN + + + P L+A++D+YG + VQ+ S++ + LR TA
Sbjct: 175 KGRVFHRINDSAVMLFFSGVRTADP-LWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTA 233
Query: 171 MELCLVQAE-DDPNNDDTLTSSEIDVA----GLPSAPFPKETQNIYVPMSSEGACSSAQD 225
+ ++ E DD +L + A P+A P QN S +
Sbjct: 234 LRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIP-QNSLNSQHSRALPAQLDG 292
Query: 226 HLRFHP-RCGILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWS 284
LRFH R G V++ A D+ +V T RP+ E +++ R
Sbjct: 293 DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARP 350
Query: 285 GSVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAET 344
G++ GVTT +P T+R P+ + + C G L +
Sbjct: 351 GALSFGVTTCDPGTLR-PADLPFSPEALVDRK------EFWAVCRVPG-----PLHSGDI 398
Query: 345 VGLLRKSNGELHYFINGVDQG--VATDKVEPQVWGVVDLYGMTVKVSIVDPCEDMDSNIQ 402
+GL+ ++GELH NG G + D +P +W + L+G ++ I+ + I
Sbjct: 399 LGLVVNADGELHLSHNGAAAGMQLCVDASQP-LWMLFGLHGTITQIRILGSTILAERGIP 457
Query: 403 HIP 405
+P
Sbjct: 458 SLP 460
Score = 37.1 bits (82), Expect = 0.52
Identities = 42/165 (25%), Positives = 67/165 (40%), Gaps = 17/165 (10%)
Query: 1 MKFHR-RCGDRVTLLNDNSTAIRNFVEFNHGLILSAEPISDDVMFEVCIDRKVNVWNGSL 59
++FH R G V +L++ + A L+ ++ P+ V + R G+L
Sbjct: 294 LRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGAL 353
Query: 60 EIGVTTLDPEFMELPATATKLRNTAWIMSGSSIV--KDGVTLVNSYGPELDTLREGDCLG 117
GVTT DP + PA S ++V K+ + GP L GD LG
Sbjct: 354 SFGVTTCDPGTLR-PADLP--------FSPEALVDRKEFWAVCRVPGP----LHSGDILG 400
Query: 118 VMRTSKAELTFYINGRCLGV-AAKDLPPRLFAVIDLYGQCVQVSI 161
++ + EL NG G+ D L+ + L+G Q+ I
Sbjct: 401 LVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRI 445
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 87 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 130
Score = 35.9 bits (79), Expect = 1.2
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
Query: 286 SVEVGVTTHNPATIRFPSTMTNMDSGTIMMSGCKVLLNGHGTCMEYGNFNLDDLREAETV 345
++ +G T+ +P+ I S + SG E+ N E +
Sbjct: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG----FWAKALPEEFAN-------EGNII 168
Query: 346 GLLRKSNGELHYFIN--GVDQGVATDKVEPQVWGVVDLYGMTVKVSIVD 392
G + + IN V + + +W +VD+YG+T V ++D
Sbjct: 169 AFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLD 217
>AL121929-2|CAI13959.1| 108|Homo sapiens neuralized homolog
(Drosophila) protein.
Length = 108
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 12 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 55
>AL121929-1|CAI13958.1| 199|Homo sapiens neuralized homolog
(Drosophila) protein.
Length = 199
Score = 36.7 bits (81), Expect = 0.68
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 644 SEFNDAVLFSSRPLRECDMFELRIDKMVDCWIGSLEIGVTAIRP 687
+ F +A+ FS+RP+ + L+I K CW G+L +G T+ P
Sbjct: 70 ASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDP 113
Score = 33.5 bits (73), Expect = 6.4
Identities = 19/74 (25%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 227 LRFHPRC-GILVKLSGNNKTAERARPLDDYNNGVVMTHRPLYDNELFEIRIDRLVDKWSG 285
L FHP G + + ++K +R + N + ++RP+ E ++I + WSG
Sbjct: 46 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 102
Query: 286 SVEVGVTTHNPATI 299
++ +G T+ +P+ I
Sbjct: 103 ALRLGFTSKDPSRI 116
>Z93020-1|CAI21594.1| 729|Homo sapiens RAN binding protein 9
protein.
Length = 729
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 271 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 327
Query: 160 SISQ 163
+ Q
Sbjct: 328 NFGQ 331
>BC052781-1|AAH52781.1| 802|Homo sapiens RANBP9 protein protein.
Length = 802
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 344 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 400
Query: 160 SISQ 163
+ Q
Sbjct: 401 NFGQ 404
>BC019886-1|AAH19886.1| 486|Homo sapiens Unknown (protein for
IMAGE:4419330) protein.
Length = 486
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 108 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 164
Query: 160 SISQ 163
+ Q
Sbjct: 165 NFGQ 168
>AL441883-5|CAI19841.1| 729|Homo sapiens RAN binding protein 9
protein.
Length = 729
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 271 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 327
Query: 160 SISQ 163
+ Q
Sbjct: 328 NFGQ 331
>AF306510-1|AAK15469.1| 500|Homo sapiens RANBPM protein.
Length = 500
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 42 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 98
Query: 160 SISQ 163
+ Q
Sbjct: 99 NFGQ 102
>AB055311-1|BAB62525.1| 729|Homo sapiens RanBPM protein.
Length = 729
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 271 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 327
Query: 160 SISQ 163
+ Q
Sbjct: 328 NFGQ 331
>AB008515-1|BAA23216.1| 500|Homo sapiens RanBPM protein.
Length = 500
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAVIDLY--GQCVQV 159
YGP T GD +G FY NG LG+A DLPP L+ + L G+ V
Sbjct: 42 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDA 98
Query: 160 SISQ 163
+ Q
Sbjct: 99 NFGQ 102
>AF064606-1|AAC17111.1| 243|Homo sapiens KB07 protein protein.
Length = 243
Score = 33.5 bits (73), Expect = 6.4
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 103 YGPELDTLREGDCLGVMRTSKAELTFYI-NGRCLGVAAKDLPPRLFAV 149
YGP T GD +G FY NG LG+A DLPP L+ V
Sbjct: 122 YGPTFTT---GDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPV 166
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 228,850,413
Number of Sequences: 224733
Number of extensions: 9621348
Number of successful extensions: 20060
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 19761
Number of HSP's gapped (non-prelim): 204
length of query: 1612
length of database: 73,234,838
effective HSP length: 100
effective length of query: 1512
effective length of database: 50,761,538
effective search space: 76751445456
effective search space used: 76751445456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 72 (33.1 bits)
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