Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000695-TA|BGIBMGA000695-PA|IPR001395|Aldo/keto reductase
(262 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 197 3e-49
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 190 3e-47
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 187 2e-46
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 185 1e-45
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 160 4e-38
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 159 5e-38
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 155 8e-37
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 152 8e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 142 1e-32
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 141 1e-32
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 140 2e-32
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 140 3e-32
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 139 8e-32
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 138 1e-31
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 138 1e-31
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 134 2e-30
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 134 2e-30
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 134 3e-30
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 133 5e-30
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 132 9e-30
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 131 2e-29
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 131 2e-29
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 130 3e-29
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 130 3e-29
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 130 3e-29
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 130 3e-29
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 130 3e-29
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 129 8e-29
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 128 1e-28
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 128 2e-28
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 128 2e-28
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 127 2e-28
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 127 3e-28
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 126 8e-28
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 126 8e-28
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 125 1e-27
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 124 2e-27
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 124 2e-27
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 124 2e-27
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 124 3e-27
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 123 5e-27
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 122 7e-27
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 122 7e-27
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 122 9e-27
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 121 2e-26
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 121 2e-26
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 121 2e-26
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 121 2e-26
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 121 2e-26
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 121 2e-26
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 120 4e-26
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 120 5e-26
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 119 7e-26
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 119 7e-26
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 119 7e-26
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 118 1e-25
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 118 1e-25
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 118 2e-25
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 118 2e-25
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 117 3e-25
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 117 3e-25
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-25
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 116 6e-25
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 115 1e-24
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 115 1e-24
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 115 1e-24
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 115 1e-24
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 114 2e-24
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 113 3e-24
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 113 3e-24
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 113 4e-24
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 113 4e-24
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 113 4e-24
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 112 7e-24
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 112 1e-23
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 112 1e-23
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 111 1e-23
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 111 1e-23
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 111 1e-23
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 111 2e-23
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 111 2e-23
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 111 2e-23
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 111 2e-23
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 110 3e-23
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 110 4e-23
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 109 5e-23
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 109 5e-23
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 109 7e-23
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 109 7e-23
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 109 7e-23
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 109 7e-23
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 109 7e-23
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 108 1e-22
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 108 1e-22
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 108 2e-22
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 108 2e-22
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 108 2e-22
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 108 2e-22
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 108 2e-22
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 107 2e-22
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 107 2e-22
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 107 2e-22
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 107 2e-22
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 107 3e-22
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 107 3e-22
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 107 3e-22
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 107 4e-22
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 107 4e-22
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 107 4e-22
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 106 5e-22
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 106 5e-22
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 106 7e-22
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 105 9e-22
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 105 1e-21
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 105 1e-21
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 105 1e-21
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 105 2e-21
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 104 2e-21
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 104 2e-21
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 104 3e-21
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 104 3e-21
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 103 3e-21
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 103 3e-21
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 103 3e-21
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 103 3e-21
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 103 5e-21
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 103 5e-21
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 103 6e-21
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 101 1e-20
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 101 1e-20
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 101 1e-20
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 101 2e-20
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 100 3e-20
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 100 4e-20
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 100 4e-20
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 100 4e-20
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 100 4e-20
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 99 6e-20
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 99 6e-20
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 99 6e-20
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 100 7e-20
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 100 7e-20
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 99 1e-19
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 99 1e-19
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 99 1e-19
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 98 2e-19
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 98 2e-19
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 97 3e-19
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 97 3e-19
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 97 3e-19
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 97 4e-19
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 97 4e-19
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 97 5e-19
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 97 5e-19
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 96 7e-19
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 96 7e-19
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 96 7e-19
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 96 7e-19
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 96 9e-19
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 96 9e-19
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 95 2e-18
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 95 2e-18
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 94 3e-18
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 94 3e-18
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 94 4e-18
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 94 4e-18
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 4e-18
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 94 4e-18
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 94 4e-18
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 94 4e-18
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 93 5e-18
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 93 5e-18
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 93 5e-18
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 93 6e-18
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 93 6e-18
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 93 6e-18
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 93 6e-18
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 93 6e-18
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 93 9e-18
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 92 1e-17
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 92 1e-17
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 92 1e-17
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 92 1e-17
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 92 1e-17
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 91 2e-17
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 91 3e-17
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 91 3e-17
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 91 3e-17
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 91 3e-17
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 91 3e-17
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 90 5e-17
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 90 6e-17
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 90 6e-17
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 89 8e-17
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 89 8e-17
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 89 8e-17
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 1e-16
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 89 1e-16
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 89 1e-16
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 89 1e-16
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 88 2e-16
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 88 2e-16
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 88 2e-16
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 88 2e-16
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 87 4e-16
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 87 4e-16
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 87 6e-16
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 86 1e-15
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 85 1e-15
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 85 1e-15
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 85 1e-15
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 85 1e-15
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 85 2e-15
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 85 2e-15
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 85 2e-15
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 85 2e-15
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 85 2e-15
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 85 2e-15
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 84 4e-15
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 84 4e-15
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 84 4e-15
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 84 4e-15
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 84 4e-15
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 83 5e-15
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 83 5e-15
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 83 9e-15
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 9e-15
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 83 9e-15
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 9e-15
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 81 2e-14
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 81 4e-14
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 80 5e-14
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 80 6e-14
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 80 6e-14
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 80 6e-14
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 80 6e-14
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 79 9e-14
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 79 9e-14
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 79 1e-13
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 79 1e-13
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 79 1e-13
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 78 2e-13
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 76 8e-13
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 76 8e-13
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 76 1e-12
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 75 1e-12
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 1e-12
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 75 2e-12
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 75 2e-12
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 75 2e-12
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 75 2e-12
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 74 3e-12
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 74 3e-12
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 74 3e-12
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 74 3e-12
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 73 6e-12
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 73 6e-12
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 73 7e-12
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 73 1e-11
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 1e-11
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 72 1e-11
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 71 2e-11
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 71 3e-11
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 71 4e-11
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 70 5e-11
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 70 7e-11
UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 70 7e-11
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 69 9e-11
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 69 9e-11
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 69 2e-10
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 69 2e-10
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 68 2e-10
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 67 4e-10
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 67 5e-10
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 67 5e-10
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 66 6e-10
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 66 1e-09
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 65 1e-09
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 65 1e-09
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 64 3e-09
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 64 3e-09
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 64 3e-09
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 64 3e-09
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 64 5e-09
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 63 8e-09
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 63 8e-09
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 63 8e-09
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 62 1e-08
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 62 1e-08
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 62 1e-08
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 62 2e-08
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 61 3e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 60 6e-08
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 60 6e-08
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 60 7e-08
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 59 1e-07
UniRef50_A1UMU2 Cluster: Aldo/keto reductase; n=7; Bacteria|Rep:... 59 1e-07
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 58 2e-07
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 2e-07
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 58 3e-07
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 56 9e-07
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 55 2e-06
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 3e-06
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 54 5e-06
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 53 6e-06
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 52 2e-05
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 51 3e-05
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 51 3e-05
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 51 3e-05
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 50 5e-05
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 50 6e-05
UniRef50_Q9RL57 Cluster: Putative oxidoreductase; n=4; Actinomyc... 50 8e-05
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 50 8e-05
UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 48 2e-04
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 48 2e-04
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 48 2e-04
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 48 2e-04
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 47 4e-04
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 47 4e-04
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 7e-04
UniRef50_Q9RT75 Cluster: Oxidoreductase, putative; n=3; cellular... 46 0.001
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 46 0.001
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 45 0.002
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 45 0.002
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 45 0.002
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 45 0.002
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 44 0.003
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 44 0.003
UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 44 0.004
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 44 0.004
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 44 0.004
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 43 0.007
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 43 0.007
UniRef50_Q2UHM0 Cluster: Predicted protein; n=1; Aspergillus ory... 43 0.007
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 43 0.009
UniRef50_A2QBJ9 Cluster: Remark: AFAR is a protein in rat liver ... 43 0.009
UniRef50_P25906 Cluster: Putative oxidoreductase ydbC; n=58; Bac... 43 0.009
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 42 0.012
UniRef50_Q88ZZ9 Cluster: Oxidoreductase; n=5; Lactobacillales|Re... 42 0.012
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 42 0.012
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.012
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 42 0.016
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 42 0.016
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 42 0.021
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 42 0.021
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 42 0.021
UniRef50_A6VL42 Cluster: Aldo/keto reductase; n=3; Pasteurellace... 42 0.021
UniRef50_A2G8W6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.021
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 41 0.028
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 41 0.028
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 41 0.028
UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 41 0.028
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.028
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 41 0.028
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 41 0.037
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 41 0.037
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 41 0.037
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 40 0.048
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 40 0.048
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 40 0.064
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 40 0.085
UniRef50_A6R2T3 Cluster: Predicted protein; n=1; Ajellomyces cap... 40 0.085
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 40 0.085
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.11
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 39 0.11
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 39 0.11
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 39 0.11
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 39 0.11
UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 39 0.15
UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri... 39 0.15
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 39 0.15
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 38 0.20
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 38 0.20
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 38 0.20
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 38 0.20
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 38 0.20
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 38 0.20
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 38 0.20
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 38 0.26
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 38 0.26
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 38 0.26
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 38 0.34
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 38 0.34
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 37 0.45
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 37 0.45
UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 37 0.45
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 37 0.60
UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 37 0.60
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 37 0.60
UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 36 0.79
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 36 0.79
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 36 0.79
UniRef50_A1VNV6 Cluster: Aldo/keto reductase precursor; n=7; Pro... 36 0.79
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 36 0.79
UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.0
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 36 1.0
UniRef50_A6DJ76 Cluster: Probable oxidoreductase; n=1; Lentispha... 36 1.0
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 36 1.0
UniRef50_Q22KN1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 36 1.4
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 36 1.4
UniRef50_Q0RGG9 Cluster: Putative oxidoreductase; n=1; Frankia a... 36 1.4
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 36 1.4
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.4
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_O66660 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 35 1.8
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 35 1.8
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 35 2.4
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 35 2.4
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 35 2.4
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 35 2.4
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 35 2.4
UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 35 2.4
UniRef50_A6RXG3 Cluster: Putative uncharacterized protein; n=2; ... 35 2.4
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 35 2.4
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 34 3.2
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 34 3.2
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 34 3.2
UniRef50_A6RUS6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 34 3.2
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 34 4.2
UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 34 4.2
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 34 4.2
UniRef50_A4C3J8 Cluster: Fibronectin type III domain protein; n=... 34 4.2
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 34 4.2
UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 34 4.2
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 34 4.2
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 33 5.6
UniRef50_Q47NW8 Cluster: Putative membrane protein; n=1; Thermob... 33 5.6
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 33 5.6
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 5.6
UniRef50_A3XNV0 Cluster: Aldo/keto reductase family protein; n=1... 33 5.6
UniRef50_Q4Z9J7 Cluster: ORF172; n=1; Staphylococcus phage G1|Re... 33 5.6
UniRef50_Q23JB3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.6
UniRef50_UPI0000D55D5C Cluster: PREDICTED: hypothetical protein;... 33 7.3
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 33 7.3
UniRef50_Q1NLZ9 Cluster: Isochorismatase hydrolase; n=2; delta p... 33 7.3
UniRef50_Q1LDA0 Cluster: Aldo/keto reductase; n=1; Ralstonia met... 33 7.3
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 33 7.3
UniRef50_A4ABU8 Cluster: Oxidoreductase; n=1; Congregibacter lit... 33 7.3
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_A2FUK8 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_Q0CQW8 Cluster: Predicted protein; n=3; Eurotiomycetida... 33 7.3
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 33 7.3
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 33 7.3
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 33 9.7
UniRef50_Q10KF4 Cluster: Serine carboxypeptidase II-3, putative,... 33 9.7
UniRef50_Q552C4 Cluster: Putative uncharacterized protein; n=2; ... 33 9.7
UniRef50_Q2HFK6 Cluster: Putative uncharacterized protein; n=3; ... 33 9.7
UniRef50_A7EA31 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 197 bits (480), Expect = 3e-49
Identities = 95/201 (47%), Positives = 133/201 (66%), Gaps = 4/201 (1%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
EQ QKSL+ + Y+DLYLIH+PG ++P N +R +W KL +L G + ++G
Sbjct: 95 EQCVQKSLKAFNTTYIDLYLIHWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIG 154
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
VSNFT+ HL+ L+++ ++PAVNQVE HP+Y Q L K+C + I +QAY S G +
Sbjct: 155 VSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLG--TSG 212
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEED 240
N +LL +P+V+ A +L V+ A++LL WALQQ + VIPKAV+ EHIK+N L+F I EE
Sbjct: 213 NINLLRNPIVLKIASQLNVSSARLLLNWALQQGIGVIPKAVNKEHIKDNIQLDFLIDEES 272
Query: 241 MKALNQLSEKNVKYAWDPSIV 261
M L L + +KYAWDPS V
Sbjct: 273 MNILFSLPQ--IKYAWDPSNV 291
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDL 73
L++G MP IG GTY+I+ ++V QVVD +L G+R + G R E+ +L+NL
Sbjct: 10 LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSI-DTAVGYRNEEDIGYALKNLLP 68
Query: 74 EY 75
+Y
Sbjct: 69 KY 70
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 190 bits (463), Expect = 3e-47
Identities = 102/211 (48%), Positives = 134/211 (63%), Gaps = 8/211 (3%)
Query: 53 PSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
P D GS+A QKSLE L L Y+DLYLIH+PG LP DKRN + R SW L E Y
Sbjct: 85 PKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVGDKRNPENRAQSWRVLEEFYS 144
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
+GK A+GVSN+TV H++ L++S + PAV QVE+HP Q+ L CK + QAY
Sbjct: 145 EGKFRAIGVSNYTVEHMQELLKSCK-VPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYS 203
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
S G LL++PVV+ A + TPAQVLL WA+QQ +AV+PK+ PE +KEN R
Sbjct: 204 SLG-----TGLLLSNPVVLEIAKECGRTPAQVLLRWAVQQSIAVLPKSSQPERVKENGRL 258
Query: 232 LNFKIPEEDMKALNQLSEKNVKYAWDPSIVA 262
+F+I EEDM+ L+ L + K+ WDP+ V+
Sbjct: 259 FDFEISEEDMERLSAL-DCGEKFCWDPTQVS 288
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/39 (51%), Positives = 27/39 (69%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
+LNN I MP +GLGT+R++ + VD AL+AGYR F
Sbjct: 9 LLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAF 47
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 187 bits (456), Expect = 2e-46
Identities = 93/212 (43%), Positives = 137/212 (64%), Gaps = 6/212 (2%)
Query: 52 APSDHGS--RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTE 109
+PSD+G + ++ + SL+ LD Y+DLYLIH+PG +++ N K+R +W L E
Sbjct: 102 SPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASRILENSPDNPKLRVTTWATLVE 161
Query: 110 LYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQ 169
L G + ++GVSN+TV HLE L+E G+ P VNQVE HP++ Q L +FC + I +Q
Sbjct: 162 LQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQ 221
Query: 170 AYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN 229
AY S G + +N LL DPVV A +L V+PA+VLL WALQ+ + +IPKA+ +HIK+N
Sbjct: 222 AYSSLGTSDTTN--LLEDPVVKKIASELNVSPARVLLKWALQRGLGIIPKAIKSDHIKDN 279
Query: 230 RSLNFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
L+F+I ++ M L L ++ KY+W+P V
Sbjct: 280 IKLDFEISKDQMTLLLSLPQQ--KYSWNPDNV 309
Score = 43.2 bits (97), Expect = 0.007
Identities = 15/36 (41%), Positives = 26/36 (72%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LNNG MP +G+GTY++R +++ +V+D + G+R
Sbjct: 28 LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFR 63
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 185 bits (450), Expect = 1e-45
Identities = 97/212 (45%), Positives = 130/212 (61%), Gaps = 13/212 (6%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAK----------LPAEDKRNTKMRELSWCKLTEL 110
EQ +KSL NL +Y+DLYLIH+PG + + N K R SW L++L
Sbjct: 121 EQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKL 180
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
+G + ++GVSN+TV HL+ ++ G+VPAVNQVEWHPYY Q L ++C+QH I LQA
Sbjct: 181 EREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQA 240
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
Y S G S + L D V S A L+ TP QVLL WA++Q+V ++PKA +HI+EN
Sbjct: 241 YSSLG--SSNTAELREDETVQSVAKSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQENV 298
Query: 231 SLNFKIPEEDMKALNQLSEK-NVKYAWDPSIV 261
L F+IP E MK LN L + K+AW+P V
Sbjct: 299 GLEFEIPAEQMKQLNGLRDSVGHKFAWNPETV 330
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
TF LN G +P G GTY+I +++ QV+DYALEAGYR
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYR 71
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 160 bits (388), Expect = 4e-38
Identities = 86/198 (43%), Positives = 117/198 (59%), Gaps = 7/198 (3%)
Query: 52 APSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
APSDHG RA++ +SLE LD EY+DLYLIH+PG L ED R+++ R SW L E +
Sbjct: 82 APSDHGLRAKEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSRHSEYRAQSWATLEEFH 141
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
G+ A+GVSN+T H+ L+ S + PAV Q+E P Q L C + I QAY
Sbjct: 142 ASGQFKAIGVSNYTAKHIRELLASCR-VPPAVLQIECQPKLIQRELRDLCMETGIHFQAY 200
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
S G +LL +P V+ TPAQVLL WALQQ ++V+P++ P + EN
Sbjct: 201 SSLG-----KGALLREPEVMDIVRHCGRTPAQVLLRWALQQGISVLPRSSQPSRVLENAQ 255
Query: 232 L-NFKIPEEDMKALNQLS 248
+ +FK+ E DMK L+ L+
Sbjct: 256 VFDFKLNETDMKRLDDLN 273
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAE--QA 63
I+P+ +++ G MP +GLGTY+++ + + Q V AL+AGYR F + +G+ A Q
Sbjct: 2 IVPSVRLMS-GTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQV 60
Query: 64 YQKSLENLDLEYVDLYLIH--FPGGAKLPAEDKRNTKMRELSWCKLTELY 111
++ L L D+++I P L A++ + +L C+ +LY
Sbjct: 61 LKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLRSLEQLD-CEYIDLY 109
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 159 bits (387), Expect = 5e-38
Identities = 88/210 (41%), Positives = 128/210 (60%), Gaps = 20/210 (9%)
Query: 54 SDHGS-RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
+D GS + +A + SL+ L +++VDLYLIHFP +K R SW +L +LY
Sbjct: 86 ADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSK-----------RMDSWKELEKLYH 134
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
D A+GVSN+T+ HL L++ N + PAVNQVE+HP+ Q L ++CK+H I L+AY
Sbjct: 135 DKLCKAIGVSNYTIIHLTELLK-NSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAY- 192
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
+ ++ + DP + A K + TPAQ+L+ WA++Q + VIPK++ E I EN +
Sbjct: 193 ----SPLAHGQKIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPKSIKKERIIENSKV 248
Query: 232 LNFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
+F I EEDMK LN L E + + WDPS V
Sbjct: 249 FDFAISEEDMKILNSLDE-DFRTCWDPSEV 277
Score = 41.9 bits (94), Expect = 0.016
Identities = 20/49 (40%), Positives = 29/49 (59%)
Query: 1 MASSDPIIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
M + + + T +LNNGI MP +GLG ++ + + V ALEAGYR
Sbjct: 1 MNNKENPLKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYR 49
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 155 bits (377), Expect = 8e-37
Identities = 83/212 (39%), Positives = 132/212 (62%), Gaps = 6/212 (2%)
Query: 52 APSDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
APS+ G +A ++ ++SL NL +EY+DL LIH+PG + L +E+ N K+R SW + E+
Sbjct: 79 APSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSS-LKSENPANKKLRVESWNVMCEM 137
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
+GK+ +VGVSNF + HLE L + ++ +VPAVNQVE+HP++ Q L K+C +++I QA
Sbjct: 138 MAEGKLRSVGVSNFEICHLEELKKDSN-VVPAVNQVEYHPHFHQDDLVKYCNENNIHFQA 196
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN- 229
Y S G + L +P++ A K V +LL +A Q ++V+P+ +PEH+ N
Sbjct: 197 YSSLGSPT-YRKQLSEEPLIKELAQKYNVEIPVLLLGFAYCQGISVLPRTTNPEHVATNF 255
Query: 230 RSLNFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
+ I +ED+ L L+ ++ K WDP +V
Sbjct: 256 KVTKLAITQEDIDRLLALTVEH-KTCWDPRVV 286
Score = 37.5 bits (83), Expect = 0.34
Identities = 16/38 (42%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+V NN MP IG+GT+++++ +I+ QV+D + GYR
Sbjct: 6 YVKNN---MPLIGIGTWQVQKEEILRQVIDAGFKEGYR 40
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 152 bits (369), Expect = 8e-36
Identities = 77/212 (36%), Positives = 127/212 (59%), Gaps = 5/212 (2%)
Query: 52 APSDHGS-RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
+P + G + ++ KSL +L Y+DL LIH+PG ++L + K N K R ++ +L L
Sbjct: 84 SPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHKDNAKFRAETYVELETL 143
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
D+GK+ ++GVSN+ + HLE L+ + ++PA+NQ E HP++ S L ++CK+ I QA
Sbjct: 144 MDEGKIRSIGVSNYEIKHLETLL-AECRILPAINQCECHPHFRNSELAEYCKEKGIHFQA 202
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN- 229
Y S GG S N LL D ++ A +PA +LL W L Q +++P+ I+EN
Sbjct: 203 YSSLGGPSYVEN-LLKDKIIKKIANAHSTSPAVILLAWGLNQGYSILPRTEKVGRIEENW 261
Query: 230 RSLNFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
++ + K+ E++MK + + +K K WDP++V
Sbjct: 262 KAKDIKLSEKEMKEIGSI-DKLSKSCWDPTVV 292
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 142 bits (343), Expect = 1e-32
Identities = 87/204 (42%), Positives = 116/204 (56%), Gaps = 20/204 (9%)
Query: 64 YQKSLENLDLEYVDLYLIHFPGGAKLPAED---KRNTKMRELS------WCKLTELYDDG 114
+ KSL +L L+Y+D YL+HFP G K ++ +R+ K+ W + L G
Sbjct: 67 FNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATG 126
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
KV ++GVSNFT+ ++ L+ S + PAVNQVE HPY QS L +CK +I L A+ F
Sbjct: 127 KVKSIGVSNFTMEQIDRLL-SVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPF 185
Query: 175 GGTSCSNN---------SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
G LL DPVVV A K TPAQVLL + +QQD+AVIPK+V P H
Sbjct: 186 GSPGRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHH 245
Query: 226 IKENRSL-NFKIPEEDMKALNQLS 248
I EN + +F + EEDM AL L+
Sbjct: 246 ILENTKIFDFTLDEEDMNALKSLN 269
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 141 bits (342), Expect = 1e-32
Identities = 74/209 (35%), Positives = 124/209 (59%), Gaps = 7/209 (3%)
Query: 52 APSDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
+P + G +A++A Q L L+++Y+D LIH+PG +KLP D +N ++R +W L EL
Sbjct: 89 SPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSKLPPNDPKNAQIRLETWKALIEL 148
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
G + +GVSNF + HL+ L+E + P +NQ E HP +FC+++ I ++A
Sbjct: 149 RKAGVIKHIGVSNFNINHLQHLIEKSE-FKPEMNQFEIHPLCFNKKTIEFCQKNGILVEA 207
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
Y + + ++ P++ A K + T AQV+L WALQ ++ +IPK+ P+ I+EN
Sbjct: 208 YSPL---ARQHEKVMKHPLINQLAQKYKKTVAQVILRWALQNNMVIIPKSKTPQRIQENI 264
Query: 231 S-LNFKIPEEDMKALNQLSEKNVKYAWDP 258
L+F + ++++ +NQL E N+ WDP
Sbjct: 265 DILDFALSPQELEQMNQLDE-NLHTCWDP 292
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 140 bits (340), Expect = 2e-32
Identities = 86/248 (34%), Positives = 141/248 (56%), Gaps = 17/248 (6%)
Query: 16 NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDLEY 75
N ++ + GL +I++ D+ + +E GY A +A++ SL+ L L+Y
Sbjct: 72 NEMVTKNDGLDGKKIKREDLFITSKCSFMEQGYE---------NALKAFESSLKKLQLDY 122
Query: 76 VDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMES 135
+D YLIH+PG L D N+ R +W L +LY D KV ++GVSN+T+ HL L+ S
Sbjct: 123 LDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSS 182
Query: 136 -NHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTA 194
N + PA+NQVE+HP Q L +FCK + I L++Y S G LLN+ V A
Sbjct: 183 PNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESYGSLAG-----GRLLNNESVKEFA 237
Query: 195 LKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS-LNFKIPEEDMKALNQLSEKNVK 253
K+ TP+Q+LL + L+ + VIPK + + EN+ L+F + ++ + +L++L+ K+ +
Sbjct: 238 KKVGRTPSQLLLRYCLEHNCPVIPKTENVHRLIENQMILDFTLSDDIVNSLDKLN-KDQR 296
Query: 254 YAWDPSIV 261
+ +P+ V
Sbjct: 297 FYMNPNSV 304
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 140 bits (339), Expect = 3e-32
Identities = 67/190 (35%), Positives = 121/190 (63%), Gaps = 7/190 (3%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+ ++A+Q++L+ L ++Y+DLYLIH+P K +D K+ +W + +LY++GK+ A
Sbjct: 90 QTKKAFQETLDRLQMDYLDLYLIHWPANEKQFGDDA--AKINAETWRAMEDLYNEGKIRA 147
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF H+ LM++ + PAV+Q+E HP + + + K+ + H+I ++A+ GG
Sbjct: 148 IGVSNFMPHHIAELMKTAK-VAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAPLGGQG 206
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
+L +P ++ A K + TPAQV L W LQQ + +PK+VH E + N+++ +F++
Sbjct: 207 AK---VLTNPTMIQIADKYQKTPAQVCLRWVLQQGILPLPKSVHKERMISNQNIFDFELT 263
Query: 238 EEDMKALNQL 247
+EDM+ ++ L
Sbjct: 264 DEDMRKISLL 273
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 4/74 (5%)
Query: 8 IPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR-MFAPSDHGSRAEQAYQK 66
I +TF LNNG+ +P +G GT+R +D+ Q V A+E GYR + + +G+ E+A K
Sbjct: 7 INSTFNLNNGVKIPCVGYGTFR-TPADVAEQAVKEAIETGYRHIDTAAVYGN--EEAVGK 63
Query: 67 SLENLDLEYVDLYL 80
+++ ++ DL++
Sbjct: 64 GIKDSGIKREDLFV 77
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 139 bits (336), Expect = 8e-32
Identities = 93/269 (34%), Positives = 146/269 (54%), Gaps = 49/269 (18%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR-----MFAPSDHG-SRA------- 60
LNNG++MP +G G +++ + + V + V AL GYR M ++ G RA
Sbjct: 6 LNNGLVMPQLGYGVFKVPEQE-VYEAVREALRVGYRSIDTAMIYENEAGVGRALKDSGIP 64
Query: 61 -------------EQAYQKSL-------ENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMR 100
+Q Y+++L + L ++YVDLYLIH+P +P ED +
Sbjct: 65 REDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWP----MPDED-----LY 115
Query: 101 ELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKF 160
+W L +LY DGK A+GVSNF + HL ++E +VPAVNQ+E HP+ +Q ++ F
Sbjct: 116 MDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEG-TVVPAVNQIELHPFLSQEAIRAF 174
Query: 161 CKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
C+++ I ++A+ L DPV+ A + TPAQV+L W LQ D+ IPK+
Sbjct: 175 CQKNGIVVEAWSPL----MKGRDALTDPVITDIAARHGKTPAQVVLRWHLQHDIIAIPKS 230
Query: 221 VHPEHIKENRSL-NFKIPEEDMKALNQLS 248
V P I+EN + +F + +DM+ ++QL+
Sbjct: 231 VTPSRIQENLDIFDFVLSPDDMRQIDQLN 259
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 138 bits (335), Expect = 1e-31
Identities = 80/201 (39%), Positives = 112/201 (55%), Gaps = 17/201 (8%)
Query: 53 PSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGA------KLPAEDKRNTKMRELS--- 103
P +H SR +++QKSLENL EY+DLYL+HFP P + K+
Sbjct: 82 PWNHHSRVAESFQKSLENLGTEYIDLYLVHFPQRVFYDETTDFPRNPDGSIKVVNSPTLN 141
Query: 104 --WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
W + L D GKV A+GVSN+++ LE L+++ +VPAVNQVE HP+ QS L +C
Sbjct: 142 DVWADVETLLDTGKVKAIGVSNYSIKTLEELLKTAK-VVPAVNQVELHPFLAQSKLLAYC 200
Query: 162 KQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAV 221
K+ I + AY T ++L DP +V A K V+PAQ++L W L + VA PK+
Sbjct: 201 KEKGIAVTAY-----TPTGYQTVLTDPTIVELAGKYGVSPAQIVLAWHLSRGVAAAPKSA 255
Query: 222 HPEHIKENRSLNFKIPEEDMK 242
+ KEN +L F PE+ K
Sbjct: 256 NESRQKENLNLPFLQPEDVAK 276
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 138 bits (334), Expect = 1e-31
Identities = 73/191 (38%), Positives = 122/191 (63%), Gaps = 12/191 (6%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRN-TKMRELSWCKLTELYDDGKVNAV 119
++A+ K L++LDLEY+DL LIH+P G K N ++ +W + E Y +GK+ A+
Sbjct: 96 KKAFHKILKDLDLEYLDLLLIHWPIGKGF----KDNWQEVNAQTWKAMEEFYLEGKIKAI 151
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
G+SNF V H+E L +S ++P VNQ+E+HP Y Q + ++C++++I +QA+ F
Sbjct: 152 GLSNFLVHHIEALKKSAK-ILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPF----- 205
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
S + +L + +V A K EVT AQ++L W +Q+D+ +PK+ PE I+ N + NF I +
Sbjct: 206 SQSKVLENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSKTPERIRSNFDVFNFGINQ 265
Query: 239 EDMKALNQLSE 249
D+K ++QL++
Sbjct: 266 ADLKVIDQLND 276
Score = 38.7 bits (86), Expect = 0.15
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+L N MPSIG GTY++ ++ V ALE GYR
Sbjct: 15 LLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYR 51
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 134 bits (325), Expect = 2e-30
Identities = 74/200 (37%), Positives = 115/200 (57%), Gaps = 16/200 (8%)
Query: 64 YQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSN 123
+ KSL+NL L+Y+DL+LIH+P N ++ S+ L LY++GK+ A+GV N
Sbjct: 90 FNKSLDNLGLDYLDLFLIHWPC---------ENDQLYIESYKALEHLYEEGKIKAIGVCN 140
Query: 124 FTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNS 183
F + HLE LM+ + P VNQ+E HPY+ Q + FC +H I + A+ N
Sbjct: 141 FKIHHLEKLMKETK-ITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMPL----MRNKG 195
Query: 184 LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMK 242
LL+DPV+ A + + TPAQ++L W L + +IPK+ P+ IKEN + +F + D+
Sbjct: 196 LLDDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIPKSQTPKRIKENFDIFDFNLELTDVA 255
Query: 243 ALNQLSEKNVKYAWDPSIVA 262
++ L+ KN + DP V+
Sbjct: 256 EIDSLN-KNARQGKDPDDVS 274
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 134 bits (324), Expect = 2e-30
Identities = 78/199 (39%), Positives = 115/199 (57%), Gaps = 10/199 (5%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLP-AEDKRNTKMRELSWCKLTELYD 112
R A Q +L+ L LEY+DLYLIH+P G +K P A D + M + W ++ L
Sbjct: 125 RVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGV-WREMENLSK 183
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
D V +GV NFTV L L+ L+PAV Q+E HP + + +FCK++ I + AY
Sbjct: 184 DSLVRNIGVCNFTVTKLNKLLGFAE-LIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYS 242
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
G L++D V A KL TP Q+L+ W LQ+ +VIPK+++PE IKEN +
Sbjct: 243 PLGSQE-GGRDLIHDQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKV 301
Query: 232 LNFKIPEEDMKALNQLSEK 250
++ IPE+D +ALN ++++
Sbjct: 302 FDWVIPEQDFQALNSITDQ 320
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 134 bits (323), Expect = 3e-30
Identities = 78/198 (39%), Positives = 112/198 (56%), Gaps = 10/198 (5%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFP----GGAKLPAEDKRNTKM-RELSWCKLTELYDD 113
R A + +L++L L+Y+DLY IH+P GA +P E + E W ++ L D
Sbjct: 98 RVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPPEAGEVLEFDMEGVWKEMENLVKD 157
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G V +GV N+TV L L+ S + PAV Q+E HP + +++ CK+H I + AY
Sbjct: 158 GLVKDIGVCNYTVTKLNRLLRSAK-IPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSP 216
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSL 232
G S +L +DPVV A KL TP QVL+ WALQ+ +VIPK+ E IKEN +
Sbjct: 217 LGS---SEKNLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVF 273
Query: 233 NFKIPEEDMKALNQLSEK 250
++IPEED K L + ++
Sbjct: 274 GWEIPEEDFKVLCSIKDE 291
Score = 35.1 bits (77), Expect = 1.8
Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
FVL +G MP++GLGT+R SD V EAGYR
Sbjct: 16 FVLKSGHAMPAVGLGTWR-AGSDTAHSVRTAITEAGYR 52
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 133 bits (321), Expect = 5e-30
Identities = 71/211 (33%), Positives = 119/211 (56%), Gaps = 12/211 (5%)
Query: 53 PSDHGSRA-EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
P D+G ++ +QA + S L ++Y+DLYL+H+P + +P + ++ +W L ELY
Sbjct: 88 PGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPD-SMVPGRSSQEVRLE--TWRALEELY 144
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
D+G A+GVSNF + HL L +S G+VP VNQVE+HP+ L + C++ +I + Y
Sbjct: 145 DEGLCRAIGVSNFLIPHLNELKDSG-GIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGY 203
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-R 230
C + L P ++ A K + +Q+ + W++Q V IPK+ P+ I EN +
Sbjct: 204 CPL-----AKGQALTHPHILELAKKYGRSASQICIRWSIQNGVVTIPKSTKPDRIYENCQ 258
Query: 231 SLNFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
F++ + +M AL+ L + +WDP+ V
Sbjct: 259 VFGFRLEDSEMAALSTLHDGR-HVSWDPTHV 288
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 132 bits (319), Expect = 9e-30
Identities = 77/209 (36%), Positives = 120/209 (57%), Gaps = 6/209 (2%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGA-KLPAEDKRNTKMRELSWCKL 107
++++ H A +SL+ L LEY+DLY+IH P A K E E +W ++
Sbjct: 78 KLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTEEIIPIEETWREM 137
Query: 108 TELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHIT 167
+L ++G V ++GVSNF + LE L+ + PAVNQ E+H YY + L++FCK+H+I
Sbjct: 138 EKLVEEGLVKSIGVSNFNIKKLEELLAIAK-IQPAVNQFEFHIYYQRPKLHQFCKKHNIH 196
Query: 168 LQAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
+ YC G G S + + VV + A K AQ+ + +++ +VIPK+VH E
Sbjct: 197 ITGYCPLGNPGISSGVPAPFENEVVKAIAKKHNKKAAQICIKFSIASGHSVIPKSVHEER 256
Query: 226 IKENRSL-NFKIPEEDMKALNQLSEKNVK 253
IKEN + +F++ EEDM+ L L +KN+K
Sbjct: 257 IKENGEVFDFELDEEDMEKLRGL-DKNIK 284
Score = 34.7 bits (76), Expect = 2.4
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
F LNNG +P +GLGT+ + V + V+ A++ GYR
Sbjct: 5 FTLNNGYKIPKLGLGTWMSANGE-VGKAVEIAIKNGYR 41
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 131 bits (317), Expect = 2e-29
Identities = 78/198 (39%), Positives = 117/198 (59%), Gaps = 19/198 (9%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
QA+ SLE L L+Y+DLYLIH+PG N +E SW L LY +GKV A+GV
Sbjct: 95 QAFNDSLERLGLDYLDLYLIHWPG----------NNSYKE-SWQALETLYAEGKVKAIGV 143
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SNF V HLE L+ S +VP +NQVE HP Q + FC++H I +QA+ +
Sbjct: 144 SNFQVHHLEDLL-SYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAW-----SPLMQ 197
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
LL++ +++ A + AQV+L W +QQD+ + K+VH E + N ++ +F++ E+
Sbjct: 198 GQLLSNETILAIAENHNKSAAQVILRWDIQQDILLAVKSVHKERMISNAAVFDFELSAEE 257
Query: 241 MKALNQLSEKNVKYAWDP 258
M +NQL+E +++ DP
Sbjct: 258 MAQINQLNE-SLRVGPDP 274
Score = 32.7 bits (71), Expect = 9.7
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
T LNNG +P +GLG ++I + +VV+ + GYR+
Sbjct: 8 TVTLNNGTKIPGMGLGVFQIPDEE-TAKVVEEGIINGYRL 46
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 131 bits (317), Expect = 2e-29
Identities = 72/208 (34%), Positives = 124/208 (59%), Gaps = 19/208 (9%)
Query: 54 SDHGSRA-EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
+DHG A ++A++++ + L++EY+D+YLIHF L +W + ELY
Sbjct: 82 TDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSYYLE------------TWHAMEELYL 129
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
GK+ +GV+NF + HLE LM+ + + P +NQ+E HP + Q+ L+++ +H I +A+
Sbjct: 130 QGKIKVIGVANFQIQHLEELMKHSR-ITPMINQIETHPEFPQNELHQYLTKHKILHEAWA 188
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
G N +LL + V+ A E T AQV+L W +Q+ + +IPK+ +P+ IKEN L
Sbjct: 189 PLGQ---GNKALLENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPKSSNPKRIKENIQL 245
Query: 233 -NFKIPEEDMKALNQLSEKNVKYAWDPS 259
+F++ E+M+ +NQL+ +Y+ P+
Sbjct: 246 FDFELSSEEMEKINQLN-TGKRYSHSPT 272
Score = 33.9 bits (74), Expect = 4.2
Identities = 13/36 (36%), Positives = 21/36 (58%)
Query: 16 NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
NGI +P +G G Y++ + + V A++ GYR F
Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHF 47
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 130 bits (315), Expect = 3e-29
Identities = 66/184 (35%), Positives = 112/184 (60%), Gaps = 5/184 (2%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNF 124
++SL++L +Y+D+YL+H+P +D N + R++++ L E GKV ++GVSN+
Sbjct: 103 EESLQSLQTDYIDMYLVHYPKPNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNY 162
Query: 125 TVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSL 184
+ HLE L ++ + P NQ+E+HP++ + L K+CK+ +I QA+ S + L
Sbjct: 163 EIVHLEEL-KTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSL---ARHEPKL 218
Query: 185 LNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMKA 243
+ DPVVV A K + VLL WAL+Q+V ++PK+V P I EN + ++ + ED+++
Sbjct: 219 IEDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQS 278
Query: 244 LNQL 247
L L
Sbjct: 279 LTAL 282
Score = 39.1 bits (87), Expect = 0.11
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
LN+G +P +G GTY++ + V +D AL AGYRMF
Sbjct: 15 LNSGYNIPFVGFGTYKV-TGENVPPAIDAALTAGYRMF 51
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 130 bits (315), Expect = 3e-29
Identities = 68/202 (33%), Positives = 111/202 (54%), Gaps = 10/202 (4%)
Query: 53 PSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
P D G A+Q S E L +Y+D+Y+IH P +LP + +E +W ++ LY+
Sbjct: 77 PVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP---QLPDWIVNQKETKEKTWRQMELLYE 133
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
D V ++GVSN+++ L+ L+E ++P NQVE HP++ Q+ L +C + I YC
Sbjct: 134 DEHVRSIGVSNYSIEDLDELLEFA-SILPHANQVELHPWFHQADLKNYCDELGILTMGYC 192
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
+ L D + A K + +PAQ+ L W++QQ+V +PK+ +KEN ++
Sbjct: 193 PL-----AKGKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNV 247
Query: 233 -NFKIPEEDMKALNQLSEKNVK 253
+F++ EDM LN S +N K
Sbjct: 248 FDFELSAEDMNTLNSFSSQNRK 269
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 130 bits (314), Expect = 3e-29
Identities = 73/211 (34%), Positives = 125/211 (59%), Gaps = 13/211 (6%)
Query: 55 DHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPA------EDKRNTKMRELSWCKLT 108
D +R ++ +S+++L +Y+DLYLIH+P K+ A ED + + E+ W ++
Sbjct: 82 DQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPEDFLDMDITEI-WQEME 140
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
L D+G V ++G+SNFT+ +E +M+ + P +NQVE + Y Q+ L + CK ++I +
Sbjct: 141 RLVDEGLVKSIGLSNFTIPQIEKIMKMCR-IKPVINQVELNVYLQQNKLREVCKSYNIVV 199
Query: 169 QAYCSFGGTSC--SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
+AY GG S+ + L+D VVVS A K T AQ+ L W +Q + +PK+ +P +
Sbjct: 200 EAYRPIGGKPANESDKNCLDDEVVVSLAKKYNKTTAQICLRWLVQNGIIAVPKSTNPNRL 259
Query: 227 KEN-RSLNFKIPEEDMKALNQ--LSEKNVKY 254
+N + + + EDMKAL + L+++NVK+
Sbjct: 260 LQNYQVFEWSLSNEDMKALEKRNLNKRNVKF 290
Score = 38.3 bits (85), Expect = 0.20
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
F LNNG MP+IGLGT+ + V + V ALE GYR+
Sbjct: 6 FFLNNGKFMPAIGLGTWLAAPGE-VGKAVTLALENGYRL 43
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 130 bits (314), Expect = 3e-29
Identities = 71/188 (37%), Positives = 111/188 (59%), Gaps = 10/188 (5%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A +SL LDL Y+DLYLIH+P A + +D + T +W + EL +GK+ ++GVS
Sbjct: 87 ALDESLRKLDLNYIDLYLIHWPANA-INYKDWQKTNAD--TWRAMEELQAEGKIKSLGVS 143
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF HLE L ++ + P+VNQ+E+HP Y Q + +FCK H I ++++ N
Sbjct: 144 NFWPEHLEALFQTAK-VSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSPLARGKVFGN 202
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
LL + + K + + +QV L W +Q DV IPK+ PE IKEN + +F++ +E+M
Sbjct: 203 DLL-----IGLSKKYQKSVSQVCLRWIIQHDVIAIPKSSSPERIKENIDVFDFELSKEEM 257
Query: 242 KALNQLSE 249
K +N+L +
Sbjct: 258 KKINELPQ 265
Score = 33.5 bits (73), Expect = 5.6
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
LN+G +P +G GTY+ + + + + AL GYR+
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRL 41
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 130 bits (314), Expect = 3e-29
Identities = 76/188 (40%), Positives = 111/188 (59%), Gaps = 18/188 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A++KSLE L L+Y+DLYLIH+PG +DK +W L +LY DGK+ A+GVS
Sbjct: 93 AFEKSLERLQLDYLDLYLIHWPG------KDKYKD-----TWRALEKLYKDGKIRAIGVS 141
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF V HLE L++ + P VNQVE+HP TQ L +CK I L+A+ +
Sbjct: 142 NFQVHHLEELLKDAE-IKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAW-----SPLMQG 195
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
LL++ V+ A K + AQV+L W LQ +V IPK++ I EN + +F++ +EDM
Sbjct: 196 QLLDNEVLTQIAEKHNKSVAQVILRWDLQHEVVTIPKSIKEHRIIENADIFDFELSQEDM 255
Query: 242 KALNQLSE 249
++ L++
Sbjct: 256 DKIDALNK 263
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 129 bits (311), Expect = 8e-29
Identities = 72/197 (36%), Positives = 117/197 (59%), Gaps = 11/197 (5%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A+++S + L ++Y+DLYLIH+P G + + K K + SW +LY + KV A+GVS
Sbjct: 93 AFEESRQKLGVDYIDLYLIHWPRGKDILS--KEGKKYLD-SWRAFEQLYKEKKVRAIGVS 149
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF + HLE ++ + + P VNQVE HP Q+ L FC I ++A+ G
Sbjct: 150 NFHIHHLEDVL-AMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG-----QG 203
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
LL++P++ + K T AQV+L W +Q+++ IPK+VH E I+EN + +F++ ED+
Sbjct: 204 KLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDV 263
Query: 242 KALNQLSEKNVKYAWDP 258
+++ L+ N +Y DP
Sbjct: 264 MSIDALN-TNSRYGPDP 279
Score = 36.7 bits (81), Expect = 0.60
Identities = 15/36 (41%), Positives = 23/36 (63%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
L+NG+ MP GLG ++ ++ V++AL AGYR
Sbjct: 11 LSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYR 46
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 128 bits (310), Expect = 1e-28
Identities = 80/219 (36%), Positives = 125/219 (57%), Gaps = 18/219 (8%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKR-----NTK 98
+++ H SR E + ++SL +L L Y+DL+LIH P G P +D +T
Sbjct: 81 KLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNGLFIGDDTI 140
Query: 99 MRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLY 158
+W + L D G V A+GVSNFTVA ++ +++ A QVE HP+ Q+ L
Sbjct: 141 DYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELI 200
Query: 159 KFCKQHHITLQAYCSFGGT-------SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQ 211
+FCK+ IT+ AY G + ++ L+ DPVV + A K V+PAQVL+ + LQ
Sbjct: 201 EFCKKQGITVTAYSPLGSPERVLQKRATTDPLLMEDPVVCAIAKKKGVSPAQVLIRYQLQ 260
Query: 212 QDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMKALNQLSE 249
+ VAV+PK+V P I++N +LNF++ +E+ +AL L++
Sbjct: 261 RGVAVLPKSVMPSRIQQNFEALNFELSKEEFQALVNLNK 299
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 128 bits (308), Expect = 2e-28
Identities = 74/193 (38%), Positives = 112/193 (58%), Gaps = 9/193 (4%)
Query: 54 SDHGSR-AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMREL----SWCKLT 108
+DH + +A ++L++L LEYVDLYLIH+P K + + + + +W +
Sbjct: 85 TDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAME 144
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
LYD GK A+GVSNF+ L L+E + PAVNQVE HP + Q+ L +FCK + L
Sbjct: 145 ALYDSGKARAIGVSNFSTKKLADLLELAR-VPPAVNQVECHPSWRQTKLQEFCKSKGVHL 203
Query: 169 QAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
AY G GT+ + +L +P++ A KL +PAQV L W LQ +V+PK+ + I
Sbjct: 204 SAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRI 263
Query: 227 KENRSL-NFKIPE 238
KEN ++ ++ IP+
Sbjct: 264 KENFNVFDWSIPD 276
Score = 32.7 bits (71), Expect = 9.7
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T F LN G PS+GLGT++ +V V A++ GYR
Sbjct: 6 TFFKLNTGAKFPSVGLGTWQ-ASPGLVGDAVAAAVKIGYR 44
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 128 bits (308), Expect = 2e-28
Identities = 82/218 (37%), Positives = 119/218 (54%), Gaps = 23/218 (10%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGG---AKLPAED-------KRNTKMRELS------- 103
E A +SL+ L L+YVDLYL+H+P A + ED K ++ +++
Sbjct: 91 EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKT 150
Query: 104 WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESN-HGLVPAVNQVEWHPYYTQSSLYKFCK 162
W + EL GK AVGVSNF++ +L+ L+ S + L PA NQVE HP Q L FCK
Sbjct: 151 WELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCK 210
Query: 163 QHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVH 222
I ++AY G T LL +PV++ A K V P V++ W +Q+ V+PK+V+
Sbjct: 211 SKGIVVEAYSPLGSTDAP---LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVN 267
Query: 223 PEHIKENRSLNFKIPEEDMKALNQLS-EKNVKYAWDPS 259
P+ IK NR + F + ED +A+N +S EK K P+
Sbjct: 268 PDRIKTNRKI-FTLSTEDFEAINNISKEKGEKRVVHPN 304
Score = 33.9 bits (74), Expect = 4.2
Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LN G +P IGLGT++ +++D V+ AL+ GYR
Sbjct: 14 LNTGAQIPQIGLGTWQSKENDAYKAVLT-ALKDGYR 48
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 127 bits (307), Expect = 2e-28
Identities = 75/191 (39%), Positives = 113/191 (59%), Gaps = 20/191 (10%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP-GGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
E A+Q+SL+ L L+Y+DLYLIH+P G L NT W + ++ + G+ ++
Sbjct: 75 EGAFQRSLDRLGLDYIDLYLIHWPVPGCFL------NT------WKDMEKILESGRALSI 122
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GVSNF + HLE L + G+VPAVNQ+E HP L ++C+ + I +QAY
Sbjct: 123 GVSNFEIRHLEELRRVS-GIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL----- 176
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPE 238
+ + L++ V+ K TPAQ+ L WA+Q+ ++VIPK+VHPE I N R +F I +
Sbjct: 177 ARGAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERIASNARIFDFTIDQ 236
Query: 239 EDMKALNQLSE 249
EDM L+ L++
Sbjct: 237 EDMDLLDTLNQ 247
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 127 bits (306), Expect = 3e-28
Identities = 80/196 (40%), Positives = 111/196 (56%), Gaps = 14/196 (7%)
Query: 63 AYQKSLENLDLEYVDLYLIH----FPGGAKL-PAEDKRNTKMRELS----WCKLTELYDD 113
A +K+L +L L+Y+DLYLIH F G L P +D K +S W + EL +
Sbjct: 91 ACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQ 150
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G V ++GV+NFT L L+ S + PAV+Q+E HPY Q+ L FC +I + AY
Sbjct: 151 GLVKSMGVANFTAPMLLDLL-SYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSP 209
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
FG T +L DP V A L TPAQVLL WA+Q++ +VIP++ + IKEN +
Sbjct: 210 FGSTEAP---VLTDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIPRSSNATRIKENFEIA 266
Query: 233 NFKIPEEDMKALNQLS 248
F++ E M ALN L+
Sbjct: 267 TFELSNEHMAALNTLN 282
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 126 bits (303), Expect = 8e-28
Identities = 79/199 (39%), Positives = 108/199 (54%), Gaps = 21/199 (10%)
Query: 54 SDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
+DHG + +AY +SL L ++YVDLYLIHFP A + SW + EL
Sbjct: 80 TDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPVPAGVVG-----------SWEAMAELQG 128
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVP-AVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
G ++GVSNF + HLE L + H ++P VNQ+E HPY L FC++H I +QAY
Sbjct: 129 KGLTRSIGVSNFNIHHLEALQK--HSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAY 186
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
+ + L+DP++ S K TPAQVLL W+LQ+ I K+V I EN
Sbjct: 187 -----SPLTRGEKLHDPLLRSLGDKYGKTPAQVLLRWSLQKGYICISKSVQLSRIIENVD 241
Query: 232 L-NFKIPEEDMKALNQLSE 249
+ NF I DM+ L+ L E
Sbjct: 242 VFNFTISMADMEILDGLEE 260
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 126 bits (303), Expect = 8e-28
Identities = 76/199 (38%), Positives = 113/199 (56%), Gaps = 18/199 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAK-----LPAEDKRNTKMRELS----WCKLTELYDD 113
A QK+L +L L+Y+DLYLIH+P G K P ++ N + + W + EL D+
Sbjct: 92 ACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDE 151
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
G V A+G+SNF +E ++ + GL PAVNQ+E HPY TQ L ++C+ I + AY
Sbjct: 152 GLVKAIGISNFNHLQVEMIL-NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAY 210
Query: 172 CSFGG-----TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
G + SLL DP + + A K T AQVL+ + +Q+++ VIPK+V PE I
Sbjct: 211 SPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERI 270
Query: 227 KEN-RSLNFKIPEEDMKAL 244
EN + +F++ +DM L
Sbjct: 271 AENFKVFDFELSSQDMTTL 289
Score = 34.3 bits (75), Expect = 3.2
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+LNNG MP +GLGT++ V + V A++ GYR
Sbjct: 6 LLNNGAKMPILGLGTWKSPPGQ-VTEAVKVAIDVGYR 41
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 125 bits (301), Expect = 1e-27
Identities = 72/199 (36%), Positives = 114/199 (57%), Gaps = 16/199 (8%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A KS+ NL + ++LYLIH+PG ++ K E +W L ++ GK +++GVS
Sbjct: 87 ALDKSIRNLGVTSLNLYLIHWPG---------QDRKRYEETWQTLIQIRAIGKASSIGVS 137
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NFT+ HL+ ++ ++ G+VPAVNQ+E HPY+ Q L + + I ++ G
Sbjct: 138 NFTIDHLDHII-ADSGVVPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPLG-----RG 191
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDM 241
+ LNDPV+ ALK TPAQV+L W L + VIPKA ++EN + +F + EEDM
Sbjct: 192 AALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIPKASSKARLQENLEADSFALDEEDM 251
Query: 242 KALNQLSEKNVKYAWDPSI 260
+ + L + + + DP++
Sbjct: 252 QRIESLDKPDGRQGIDPAV 270
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 124 bits (300), Expect = 2e-27
Identities = 94/274 (34%), Positives = 139/274 (50%), Gaps = 45/274 (16%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGS---------- 58
T FVL+NG+ +P++G GTY+ D V+ A+ GYR F S +G+
Sbjct: 6 TQFVLSNGLSIPAVGFGTYKTGDGD--SAVLSNAIAQGYRHFDTASFYGTETALGQAVAE 63
Query: 59 ---------------RAEQAYQKSLENLD--LE-----YVDLYLIHFPGGAKLPAEDKRN 96
+ E Y +L D LE Y+DLYLIH+P L ED
Sbjct: 64 SDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP-RPDLELEDW-- 120
Query: 97 TKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSS 156
K+ +W L LY+ G V A+GVSNF HLE ++ S + + P V+Q+E+HP YTQ
Sbjct: 121 AKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASAN-VAPMVDQLEFHPGYTQDE 179
Query: 157 LYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAV 216
FC+ H I ++A+ G N L + V+ A + V+PAQ+ L +ALQ+ V
Sbjct: 180 AVAFCQNHSILVEAWSPLG-----RNRLTGNGVLTRLAAEHGVSPAQICLRFALQRGVLP 234
Query: 217 IPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
+PK+ PE + EN L +F + E+M AL+ + +
Sbjct: 235 LPKSSSPERMAENLDLFSFSLTGEEMAALSTMPQ 268
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 124 bits (300), Expect = 2e-27
Identities = 74/210 (35%), Positives = 120/210 (57%), Gaps = 14/210 (6%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRN----TKMRELS-------W 104
H E+A K+L++L +Y+DLYLIH+P + E TK L+ W
Sbjct: 83 HPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPIDPVTKRFRLANVPIADTW 142
Query: 105 CKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQH 164
L +L + K+ ++G+SNFT ++ L+++ + PAVNQ+E HPY Q L+K+ K+
Sbjct: 143 AALEKLVEAKKIRSIGISNFTQDKIDDLLKTAK-IPPAVNQIEAHPYLQQPGLHKYLKEK 201
Query: 165 HITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
+I AY G + +++DP V + A KL PA +L+ WA+Q+ AV+PK+V P
Sbjct: 202 NILSVAYSPLGNNIYNAPRVVDDPDVKAIADKLGKDPAALLISWAVQRGTAVLPKSVTPS 261
Query: 225 HIKENRSLNFKIPEEDMKALNQLSEKNVKY 254
I+ N +F IP+ + +ALN+L ++N +Y
Sbjct: 262 RIESNFQ-DFIIPDAEFEALNKL-DRNQRY 289
Score = 37.1 bits (82), Expect = 0.45
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
TF LN+G +P+IGLGT+ + + V V+ AL AGYR
Sbjct: 6 TFKLNSGYNIPAIGLGTWLSKPHE-VENAVEAALRAGYR 43
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 124 bits (299), Expect = 2e-27
Identities = 76/204 (37%), Positives = 112/204 (54%), Gaps = 18/204 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAK-----LPAEDKRNTKMREL----SWCKLT 108
S + A+QK+L +L L+Y+DLYLIH+P G K P + N + +W +
Sbjct: 87 SMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAME 146
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHI 166
+L D+G V +GVSNF +E ++ + GL PAVNQ+E HPY TQ L ++C I
Sbjct: 147 QLVDEGLVKTIGVSNFNPLQIERIL-NKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGI 205
Query: 167 TLQAYCSFGG-----TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAV 221
+ AY G + SLL DP + + A K T AQVL+ + +Q+++ VIPK+V
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSV 265
Query: 222 HPEHIKEN-RSLNFKIPEEDMKAL 244
P I EN + +F++ EDM L
Sbjct: 266 TPVRIAENLKVFDFEVSSEDMATL 289
Score = 34.7 bits (76), Expect = 2.4
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LNNG MP++GLGT++ V + V A++ GYR
Sbjct: 7 LNNGTKMPTLGLGTWKSPPGQ-VTEAVKVAIDLGYR 41
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 124 bits (298), Expect = 3e-27
Identities = 86/282 (30%), Positives = 147/282 (52%), Gaps = 52/282 (18%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF--APSDHGSR--------- 59
T+ LNNGI MP G G Y++ + ++ A++ GYR+F A H +
Sbjct: 8 TYRLNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS 67
Query: 60 ---------------AEQAYQKSL-------ENLDLEYVDLYLIHFPGGAKLPAEDKRNT 97
EQ Y ++L + L L+ VDLYL+H+P K++T
Sbjct: 68 GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---------KQDT 118
Query: 98 KMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSL 157
+W + +LYD+G V A+GVSNF HL+ L S + ++P V+Q+E HP++ L
Sbjct: 119 FFE--TWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSAN-VLPVVDQLETHPHFPNQLL 175
Query: 158 YKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVI 217
+++ ++ HI QA+ G +L + +++ A K +PAQ++L W LQ ++++I
Sbjct: 176 HRYLEELHIVHQAWSPLG-----RGGVLQEQILIDLAKKHGKSPAQIVLRWHLQNNISII 230
Query: 218 PKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE-KNVKYAWD 257
PK+ P I+EN + +F++ E DM+ + +L+ + V +A D
Sbjct: 231 PKSETPSRIRENADIYDFELTEADMRQVERLNNGERVSHAPD 272
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 123 bits (296), Expect = 5e-27
Identities = 67/185 (36%), Positives = 103/185 (55%), Gaps = 12/185 (6%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAED----KRNTKMREL-------SW 104
H E+A KSL +L +Y+DLYLIH+P + T + ++ +W
Sbjct: 83 HPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVNEQTGLIDVVDVPIKDTW 142
Query: 105 CKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQH 164
+ +L + GKV ++GVSNFT +E L+++ + PAVNQ+E HP+ Q L ++ Q
Sbjct: 143 AAMEKLVEKGKVRSIGVSNFTREKIEELLKTAK-ITPAVNQIEAHPFLQQRDLLEWSTQK 201
Query: 165 HITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
I + Y G + ++DP+V+ TA KL TPAQVL+ WA+Q+ V+PK+V PE
Sbjct: 202 GIVVAGYSPLGNNIYNIPRAVDDPLVIETAKKLNKTPAQVLISWAVQRGTVVLPKSVTPE 261
Query: 225 HIKEN 229
I+ N
Sbjct: 262 RIESN 266
Score = 37.9 bits (84), Expect = 0.26
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 2/52 (3%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR-MFAPSDHGSRAE 61
TF LN G MP++GLGT++ ++ D V V AL+ GYR + A + +G+ E
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK-DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 122 bits (295), Expect = 7e-27
Identities = 80/204 (39%), Positives = 117/204 (57%), Gaps = 18/204 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAK-----LPAEDKRN---TKMREL-SWCKLT 108
S ++A+Q +L +L L+Y+DLYLIH+P G + LP +DK + +K L +W +
Sbjct: 87 SLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAME 146
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHI 166
EL D G V A+GVSNF +E L+ + GL P NQVE HPY TQ L ++C I
Sbjct: 147 ELVDQGLVKALGVSNFNHFQIERLL-NKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGI 205
Query: 167 TLQAYCSFG-----GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAV 221
T+ AY G + LL P + A K + T AQVL+ + ++++V VIPK+V
Sbjct: 206 TITAYSPLGSPDRPSAKPEDPLLLEIPKIKEIAAKHKKTAAQVLIRFHIERNVVVIPKSV 265
Query: 222 HPEHIKEN-RSLNFKIPEEDMKAL 244
P I+EN + +F++ EEDM A+
Sbjct: 266 TPSRIQENIQVFDFQLSEEDMAAI 289
Score = 32.7 bits (71), Expect = 9.7
Identities = 20/71 (28%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPS---DHGSRAEQAYQKSLEN 70
L G MP +GLGT++ + V + V A++AGYR + + S +A Q+ ++
Sbjct: 7 LLTGAKMPIVGLGTWKSPPAK-VREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQE 65
Query: 71 LDLEYVDLYLI 81
++ DL+++
Sbjct: 66 KAVKREDLFIV 76
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 122 bits (295), Expect = 7e-27
Identities = 84/269 (31%), Positives = 138/269 (51%), Gaps = 25/269 (9%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGY------RMFAPSDHGSRAEQAYQKS 67
LNNGI +P +GLGTY + D V YAL+ Y ++ R +A K+
Sbjct: 6 LNNGITIPQVGLGTYLLEPDD-AQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSKA 64
Query: 68 LENLDLEYVDLYLIHFPGGAKLPAE-DKRNTKMREL------------SWCKLTELYDDG 114
+ + LE L+ F + + ++ T +L + L + + +G
Sbjct: 65 RDEIFLE-TKLWPSFFERASAVEETLERLGTDYIDLMILHQPAGDTVAGYRILEKAHKEG 123
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
K+ A+G+SNF VA + +++ +VP +NQVE HPY+ Q+ L K H+ITLQA+
Sbjct: 124 KIRAIGLSNFDVAQTQRILDECE-VVPTINQVECHPYFPQTELKALLKDHNITLQAWYPL 182
Query: 175 GGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-N 233
GG N+S++++P+V A + +PAQVLL W +QQ VIP + P HI +N L +
Sbjct: 183 GGR--GNDSIMSEPIVQGLAEEHSKSPAQVLLRWHIQQGHIVIPGSKTPSHIAQNIDLFD 240
Query: 234 FKIPEEDMKALNQLSEKNVKYAWDPSIVA 262
F + +EDM ++ L + + + ++A
Sbjct: 241 FALTDEDMAQIDSLDKGKPFFEHNDEVLA 269
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 122 bits (294), Expect = 9e-27
Identities = 66/189 (34%), Positives = 110/189 (58%), Gaps = 19/189 (10%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
+ A+Q++L+ L L+Y+DLYLIH+P L SW + +LY GK+ +G
Sbjct: 96 QAAFQETLDKLGLDYLDLYLIHWPAPGYLD------------SWRAMEDLYKAGKIKNIG 143
Query: 121 VSNFTVAHLEGLMESNHGLV-PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
VSNF + ++ HG V P V+Q+E HPY+ Q+ ++ + + I +A+ GG
Sbjct: 144 VSNFNQTQMADILA--HGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPLGG--- 198
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
NN+ L D V+ A +V+ AQ++L W +Q++ VIPK++H I++NR + F + E
Sbjct: 199 GNNNALTDSVINELAAAHDVSAAQIILRWHVQREEVVIPKSIHEARIQQNRDIFAFGLDE 258
Query: 239 EDMKALNQL 247
++MKA++ L
Sbjct: 259 DEMKAISDL 267
Score = 36.3 bits (80), Expect = 0.79
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+NNG +P +GLG +++ ++ + +AL AGYR
Sbjct: 16 MNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYR 51
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 121 bits (292), Expect = 2e-26
Identities = 95/283 (33%), Positives = 140/283 (49%), Gaps = 50/283 (17%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR------MFAPSDHGSRA------ 60
+LNNG+ MP +G G +++ D V ALEAGYR ++ + RA
Sbjct: 9 ILNNGVEMPQLGFGVWQVPDDD-AQTAVALALEAGYRSIDTAAIYGNEEGTGRAIAASGL 67
Query: 61 --------------EQAYQKSLENLD-------LEYVDLYLIHFPGGAKLPAEDKRNTKM 99
+Q Y +L D LEY+DLYLIH+P +PA+++
Sbjct: 68 AREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWP----MPAKERYVDTY 123
Query: 100 RELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYK 159
+ +L DG+V A+GVSNF HLE L + ++PAVNQ+E HP+ Q + +
Sbjct: 124 KAFE-----KLLADGRVRAIGVSNFLPEHLERL-TAETSVIPAVNQIELHPHLQQHAARE 177
Query: 160 FCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPK 219
+ I +A+ G S +L+ P +V+ A K TPAQV+L W LQ VIPK
Sbjct: 178 VHAEQGIATEAWSPLG----SGKGILDIPAIVAIAQKHGRTPAQVVLRWHLQLGNVVIPK 233
Query: 220 AVHPEHIKENRSL-NFKIPEEDMKALNQLSEKNVKYAWDPSIV 261
+V P IKEN + F + ED+ A++ L+E + DP+ V
Sbjct: 234 SVTPSRIKENIDVFGFSLDTEDLAAISALNEDR-RLGSDPADV 275
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 121 bits (292), Expect = 2e-26
Identities = 74/206 (35%), Positives = 117/206 (56%), Gaps = 19/206 (9%)
Query: 55 DHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
DHG A A+++S + L +EYVDLYLIH+PG + E +W +LY+
Sbjct: 82 DHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNRSYIE----------TWRAFEKLYEM 131
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
KV A+GVSNF HL+ L+ +N + P VNQVE HP++ Q +L +C + +I + A+
Sbjct: 132 KKVRAIGVSNFEPHHLDDLL-ANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRP 190
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
G +LL +P +V A K + + AQV++ W +Q V IPK+ H E IK+N +
Sbjct: 191 LG-----KGALLTEPQLVELAEKHKRSAAQVIIRWLIQLGVIAIPKSSHEERIKQNFDVF 245
Query: 233 NFKIPEEDMKALNQLSEKNVKYAWDP 258
+F++ EDM+ + + ++N + P
Sbjct: 246 DFELSPEDMRRIESM-DRNSRIGSSP 270
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/71 (23%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLE 69
T L+NG+ +P +G+GT+ + + V+ + +A+ AGYR + H + E+ + +
Sbjct: 6 THVTLSNGVQVPQLGIGTWEAKDGNEVVN-IKWAVNAGYR-HVDTAHYYKNEKGVGQGIS 63
Query: 70 NLDLEYVDLYL 80
+ D+++
Sbjct: 64 ECGVPRSDIFV 74
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 121 bits (291), Expect = 2e-26
Identities = 75/198 (37%), Positives = 112/198 (56%), Gaps = 18/198 (9%)
Query: 54 SDHGSRA-EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
SD G + ++A++KSL+ L LEY+DLYLIH P G +W + E+Y
Sbjct: 83 SDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFGDV------------HCAWKAMEEMYK 130
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
DG V A+GVSNF L LM +H +VPAVNQ+E HP+Y + +F + ++I +A+
Sbjct: 131 DGLVRAIGVSNFYPDRLMDLMV-HHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWG 189
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
F ++ + V+ S A K T AQV+L W Q+ + IPK V E +KEN S+
Sbjct: 190 PFAE---GRKNIFQNGVLRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVRRERMKENISI 246
Query: 233 -NFKIPEEDMKALNQLSE 249
+F++ +EDM+ + L E
Sbjct: 247 FDFELTQEDMEKIATLDE 264
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 121 bits (291), Expect = 2e-26
Identities = 89/288 (30%), Positives = 144/288 (50%), Gaps = 45/288 (15%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF--------------A 52
++ T + L NG+ +P + GT++I + Q V AL AGYR A
Sbjct: 3 VLTTMYQLANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA 62
Query: 53 PSDHGSRAEQ------------AYQKSLENLD-------LEYVDLYLIH--FPGGAKLPA 91
D G EQ +YQ +L + D L+YVDLYL+H +P G
Sbjct: 63 IRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWGQVGRV 122
Query: 92 EDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPY 151
D+ N + W + +Y G+ A+GVSNF V L+ ++ + + P VNQ++++
Sbjct: 123 YDEANLDV----WQAMEAIYQSGRAKAIGVSNFAVRDLKNIL-NQATIPPMVNQIQYYLG 177
Query: 152 YTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQ 211
+T+ + KF ++H + ++AY + + +L++P V + A K V+ AQ+ L + LQ
Sbjct: 178 FTEPKITKFSEEHAMLVEAY-----SPLATGGVLDNPQVQAYADKYGVSVAQLALRFVLQ 232
Query: 212 QDVAVIPKAVHPEHIKENRSLNFKIPEEDMKALNQLSEKNVKYAWDPS 259
V +PKAV+P HI+ N L+F I DM+ALN L + Y +P+
Sbjct: 233 NGVLPLPKAVNPAHIEANTQLDFAISVADMQALNDLPDAAGSYMHNPT 280
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 121 bits (291), Expect = 2e-26
Identities = 71/199 (35%), Positives = 116/199 (58%), Gaps = 16/199 (8%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+AY++S L +DLYLIH+P +PA+ + +W L EL G+V ++GV
Sbjct: 92 RAYEESARLLRRPVLDLYLIHWP----MPAQGQYVE-----TWKALVELKKSGRVKSIGV 142
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SNF HLE +M++ G+VP VNQ+E HP + Q +L +F ++H+I +++ G
Sbjct: 143 SNFESEHLERIMDAT-GVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPLG-----K 196
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+L+D + A K TPAQV++ W LQ + VIPK+V+P+ + EN + F + +D
Sbjct: 197 GRVLSDERIGKIAEKHSRTPAQVVIRWHLQNGLIVIPKSVNPKRLAENLDVFGFVLDADD 256
Query: 241 MKALNQLSEKNVKYAWDPS 259
M+A+ Q+ K+ + DP+
Sbjct: 257 MQAIEQMDRKDGRMGADPN 275
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 121 bits (291), Expect = 2e-26
Identities = 82/208 (39%), Positives = 110/208 (52%), Gaps = 17/208 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFP-------GGAKLP-----AEDKRNTKMRELSWC 105
+R E +SL+ L L+YVDLYL+H+P K P + D +T +W
Sbjct: 86 TRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFPKHADGSRDIIHTHNHVDTWK 145
Query: 106 KLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHH 165
+ +L GK AVGVSN++ A LE L+ + VPAVNQVE HP Q L FCK+
Sbjct: 146 LMEKLPATGKTKAVGVSNYSKAWLEQLLP-HATTVPAVNQVENHPQLPQQELVDFCKEKG 204
Query: 166 ITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
I + AY G T LL VV A K ++PA VLL + + + + VIPK+V+P+
Sbjct: 205 IHIMAYSPLGST---GGPLLTAEPVVKIAEKHSISPAAVLLGYQIARGITVIPKSVNPDR 261
Query: 226 IKENRSLNFKIPEEDMKALNQLSEKNVK 253
IK N L + EDMK LN SE+ K
Sbjct: 262 IKANAQLK-DLDAEDMKLLNDYSEQLAK 288
Score = 33.5 bits (73), Expect = 5.6
Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAE--QAYQKSL 68
F LN G +P+ GLGT++ ++ + V A+++GYR+ +G+ E Q ++++
Sbjct: 6 FTLNTGAKIPAFGLGTWQ-GDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAI 64
Query: 69 ENLDLEYVDLYLI 81
+ ++ DL+++
Sbjct: 65 SSGIVKREDLFVV 77
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 120 bits (289), Expect = 4e-26
Identities = 77/207 (37%), Positives = 122/207 (58%), Gaps = 21/207 (10%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNT-------KMRELSWCKLTELYDDGK 115
A +++L +L L+Y+DLYL+H+P + + D + + +RE +W ++ +L D G
Sbjct: 93 ALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRE-TWEEMEKLVDAGL 151
Query: 116 VNAVGVSNFTVAHLEGLME--SNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
V ++G+SNF V +GLME S + PA NQVE HP+ +Q L KFC +H+I L AY
Sbjct: 152 VKSIGLSNFNV---QGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSP 208
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
G N + +++ V + A K T VL WA+Q++ +VIPK+ P + EN L
Sbjct: 209 LG-----NGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLF 263
Query: 233 NFKIPEEDMKALNQLSEKNVKYAWDPS 259
NF+I E DM L+++ +KN++ DP+
Sbjct: 264 NFEIEEADMLFLDKM-DKNLR-TCDPA 288
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 120 bits (288), Expect = 5e-26
Identities = 77/208 (37%), Positives = 104/208 (50%), Gaps = 7/208 (3%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
+D E A +SL+ L LEYVDLYLIH+P E + +W L ++Y +
Sbjct: 85 NDQHKDPEGALDESLKKLGLEYVDLYLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKE 144
Query: 114 GK-VNAVGVSNFTVAHLEGLMESNH-GLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
GK V A+GVSNF L+ L+ S +VP +NQ+E HP TQ L+ + K I + AY
Sbjct: 145 GKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAY 204
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
G S L + VV A K QVL+ W +Q+ VIPK+ E I +N
Sbjct: 205 SPLGHADAST---LKNKVVTDIAKKHNANAGQVLISWGVQRGTIVIPKSTTDERIIDNIK 261
Query: 232 LNFKIPEEDMKALNQL-SEKNVKYAWDP 258
F + +ED ALN L E+ K DP
Sbjct: 262 -TFTLSQEDFDALNNLEKEEGEKRTNDP 288
Score = 39.9 bits (89), Expect = 0.064
Identities = 19/49 (38%), Positives = 29/49 (59%)
Query: 1 MASSDPIIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
M+S I T+ LNNG+ +P+IGLGT+ + D + AL+ GY+
Sbjct: 1 MSSQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYK 49
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 119 bits (287), Expect = 7e-26
Identities = 74/187 (39%), Positives = 105/187 (56%), Gaps = 16/187 (8%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A ++SL L LEYVDLYLIH+P +P D+ +W L ++ DG ++GV
Sbjct: 144 RAVRESLGRLQLEYVDLYLIHWP----VPKIDRYVD-----TWKALAKIKADGLARSIGV 194
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SNFT +L+ L + G+VP VNQVE HP Q L F +H I +A+ G
Sbjct: 195 SNFTPVYLQRLFDET-GIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLG-----Q 248
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+LL DPV+ A K + AQV++ W +QQ + VIPK+V P I EN ++ +F + ED
Sbjct: 249 GTLLADPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIPKSVTPSRIAENANVFDFTLDAED 308
Query: 241 MKALNQL 247
M A+ L
Sbjct: 309 MAAIASL 315
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 119 bits (287), Expect = 7e-26
Identities = 64/188 (34%), Positives = 107/188 (56%), Gaps = 12/188 (6%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A+ ++ +L L+Y+DLYLIH+P A + + ++ +W + +LY DGK+ A+GV
Sbjct: 88 KAFDNTINDLQLDYLDLYLIHWPAAAH---QFENWKQLNNDTWSAMEKLYKDGKIKALGV 144
Query: 122 SNFTVAHLEGLMESNHGLV-PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
SNF HL L++ H + P VNQ+E+HP Y Q +FC ++I ++ + G
Sbjct: 145 SNFMEHHLTPLLQ--HATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSPLG----- 197
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEE 239
+ ++ V+ A K T AQ+ + WA+Q +V +PK+V P I EN + +F I E
Sbjct: 198 RGDVFDNEVLKQLAHKYNKTVAQLSIRWAIQNNVIPLPKSVTPNRIIENFEVSDFNISES 257
Query: 240 DMKALNQL 247
DM +N++
Sbjct: 258 DMALINKI 265
Score = 35.9 bits (79), Expect = 1.0
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
F LNN I +P+IG GT++ + + A++AGY+
Sbjct: 5 FKLNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYK 42
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 119 bits (287), Expect = 7e-26
Identities = 66/200 (33%), Positives = 112/200 (56%), Gaps = 18/200 (9%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+ QA + L+ L YVDL L+H+P DK N SW L ++Y DG+ A
Sbjct: 97 KLRQAVNEQLKKLQTNYVDLLLLHWP------VNDKYNE-----SWRALEDIYKDGQAKA 145
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GV NF V + L++ + + PA+NQ+E++P Q + KFC+++ I L+A+ G
Sbjct: 146 IGVCNFNVERMTDLLD-HAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAWSPLG--- 201
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
N LL++ V+ A + + +PAQV+L W +QQ V+ K HP+ +KEN + +F +
Sbjct: 202 --NGRLLSNDVIKQIADEHQKSPAQVILRWEIQQGFIVLTKTTHPQRMKENAEIFDFTLS 259
Query: 238 EEDMKALNQLSEKNVKYAWD 257
++MK +++L ++ +D
Sbjct: 260 PDEMKQIDKLDQEKHSIWYD 279
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 118 bits (285), Expect = 1e-25
Identities = 72/209 (34%), Positives = 113/209 (54%), Gaps = 18/209 (8%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
SD+ S A + SL +L Y+DL+LI P G K K R SW + E D
Sbjct: 89 SDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPAGGK---------KSRIASWKAMEEFVDS 137
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G + +VGVSN+ V HL+ L SN P VNQ+E HP+ +Q + K+C+ H I ++AY
Sbjct: 138 GDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAY-- 195
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
+ ++ LND +V A KL ++ AQ+L+ W+LQ+ I K+ EH+ + +
Sbjct: 196 ---SPLTHGIRLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVF 252
Query: 233 NFKIPEEDMKALNQLSEK-NVKYAWDPSI 260
NF IP++ ++ L+ E + +DP++
Sbjct: 253 NFTIPDDVVQELSSFDEHWHAGTTYDPTV 281
Score = 34.3 bits (75), Expect = 3.2
Identities = 15/40 (37%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
TT L NG+++P IG G + ++ ++ +V AL++GYR
Sbjct: 9 TTVTLTNGMVIPRIGFGAFMLKYNE-CYGLVTQALDSGYR 47
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 118 bits (285), Expect = 1e-25
Identities = 78/205 (38%), Positives = 109/205 (53%), Gaps = 19/205 (9%)
Query: 59 RAEQAYQKSLENLD-LEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVN 117
R ++ ++SL + LEY+DL LIH P DK K R +W L E D G V
Sbjct: 94 RTWRSLKESLNKVKHLEYIDLVLIHDP------LSDK---KTRIETWKALQEAVDSGMVK 144
Query: 118 AVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
++GVSNF H++ L + GL P VNQ+E P+ + L +C+ I L+AYC
Sbjct: 145 SIGVSNFGKHHIQELYDWE-GLKYKPIVNQIELSPWLMRKDLVDYCQNLGIVLEAYCPL- 202
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
+ + LNDP +V A K TPAQVLL W + + V VIPK++ PE + +N L +F
Sbjct: 203 ----TTGAKLNDPTLVKLAKKYNKTPAQVLLRWNIDRGVVVIPKSLKPERLPQNFDLFDF 258
Query: 235 KIPEEDMKALNQLSEKNVKYAWDPS 259
K+ +ED L +V WDPS
Sbjct: 259 KLTDEDFAELAHPDAYDVFGGWDPS 283
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 118 bits (284), Expect = 2e-25
Identities = 72/201 (35%), Positives = 115/201 (57%), Gaps = 19/201 (9%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A + SL+ L +Y+DL LIH+P E +T W L +L DG+V ++GV
Sbjct: 93 KAVEGSLKRLQTDYLDLLLIHWP-----VREHFFDT------WRALEQLKADGQVKSIGV 141
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SN+T+AHLE L+ + +P VNQVE+HPY Q +L + ++H I +A+ G
Sbjct: 142 SNYTIAHLE-LLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLG-----R 195
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+L+DP++ A + AQV+L W LQ + IPK+ HPE I+EN ++ +F + ++
Sbjct: 196 RVVLDDPMLAKMAAHHNKSVAQVILRWELQHQLVTIPKSTHPERIQENANIFDFSLDIDE 255
Query: 241 MKALNQLSEKNVKYAWDPSIV 261
M ++ L+ KN + +P IV
Sbjct: 256 MTMIDLLN-KNERTGNEPEIV 275
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 8 IPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
I T L +G MP +G GTY + + + A +AGYRMF
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMF 49
>UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative;
n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase
(GCY1), putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 274
Score = 118 bits (284), Expect = 2e-25
Identities = 83/253 (32%), Positives = 127/253 (50%), Gaps = 18/253 (7%)
Query: 8 IPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR----MFAPSDHGSRAEQA 63
+PT F LN G +P+IGLGT+R V Q V +AL+ GY F SR +
Sbjct: 3 LPTHFKLNTGAQIPAIGLGTWRSEPGQ-VRQAVSFALKNGYSHIDTAFTKLARASRIVVS 61
Query: 64 YQKSLEN-----LDLEYVDLYLIHFPGG--AKLPAEDKRNTKMREL-SWCKLTELYDDGK 115
K+ + L + P A+ +T + +W ++ E+Y GK
Sbjct: 62 LAKTFSSPANCGTPTSPTSLKVSRRPLTLWARTTLISISSTGQSDYETWRQMEEIYKAGK 121
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
V A+GV+N+++ +LE L + +VPAVNQVE HP+ Q +L ++C +H I L+AY G
Sbjct: 122 VKAIGVANWSIPYLEEL-KKKWTVVPAVNQVELHPFLPQHALKEWCDKHGILLEAYSPLG 180
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFK 235
L++DP + A K V+PA VL+ + + + V V+PK+ I NR +
Sbjct: 181 SEGA---PLMSDPAIQEMAKKYGVSPATVLISYHVNRGVVVLPKSTQENRILSNRQV-IP 236
Query: 236 IPEEDMKALNQLS 248
+ EDM LN L+
Sbjct: 237 LSPEDMDVLNGLA 249
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 117 bits (281), Expect = 3e-25
Identities = 79/225 (35%), Positives = 122/225 (54%), Gaps = 22/225 (9%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDK-----RNTK 98
++++ S R A +KSL++L L+Y+DL++IH P G PA++ NT
Sbjct: 85 KLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDLFPADENGKFIYHNTD 144
Query: 99 MRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSS 156
+R+ +W L + D G V ++GVSNF LE L+ + GL P NQVE H Y QS
Sbjct: 145 LRD-TWKALEKCKDAGLVRSIGVSNFNHKQLE-LILNMPGLKYKPVCNQVECHVYLNQSK 202
Query: 157 LYKFCKQHHITLQAYCSFGGT------SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWAL 210
L +FCK I L Y G + S LL DP + A K TPAQV + + L
Sbjct: 203 LLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAMRYHL 262
Query: 211 QQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMKALNQLSEKNVKY 254
Q+ V V+ K+ P I++N + +F++ EDM++++ L+ +N++Y
Sbjct: 263 QRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLN-RNMRY 306
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 117 bits (281), Expect = 3e-25
Identities = 71/208 (34%), Positives = 115/208 (55%), Gaps = 17/208 (8%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAK----LPAEDKRNTKM---RE 101
S + R E+ +L++L +Y+DLYLIH+P G + + RN +
Sbjct: 111 SSYHDRVEECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQA 170
Query: 102 LSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
+W ++ ++ GK A+G+SN + +E ++++ + PAVNQVE HPY Q +L K+C
Sbjct: 171 KTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGK-VTPAVNQVELHPYCPQHALLKYC 229
Query: 162 KQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAV 221
K+ I L+AY G TS + L DP +++ A K V A VL+ + + + V V+PK+V
Sbjct: 230 KEKGILLEAYSPLGSTS---SPLHEDPDLLAVAKKHNVPTATVLISYQVNRGVVVLPKSV 286
Query: 222 HPEHIKENRSLNFKIPEEDMKALNQLSE 249
P I+ N K+ EEDM L++L+E
Sbjct: 287 TPARIESNLK-TIKLDEEDMNKLDKLAE 313
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/41 (51%), Positives = 30/41 (73%), Gaps = 1/41 (2%)
Query: 9 PTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
PT+F LN G +P+IGLGT++ + + V Q V +AL+AGYR
Sbjct: 36 PTSFKLNTGASIPAIGLGTWQAKAGE-VRQAVAHALKAGYR 75
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 116 bits (280), Expect = 5e-25
Identities = 67/192 (34%), Positives = 100/192 (52%), Gaps = 15/192 (7%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKV 116
GS+ A + SL L+Y+DL L+H P G K K R SW LTEL +GKV
Sbjct: 98 GSKTRLAVEDSLAKAGLDYLDLVLLHAPDGGK---------KFRLDSWDTLTELVQEGKV 148
Query: 117 NAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG 176
++GVSNF H++ L++S ++P NQ+E HP++ Q + + H I +QAYC
Sbjct: 149 RSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAASEAHSIIVQAYCPL-- 206
Query: 177 TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFK 235
+ DP + A + T AQV+L W +Q + +PK+ + + EN L F
Sbjct: 207 ---ARGHYYGDPTLKKVAAETGKTEAQVMLRWLVQHGIVALPKSSNLQRQVENAECLTFV 263
Query: 236 IPEEDMKALNQL 247
+ +E MK L+ L
Sbjct: 264 LSDEQMKELDAL 275
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 116 bits (279), Expect = 6e-25
Identities = 65/186 (34%), Positives = 108/186 (58%), Gaps = 9/186 (4%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAED-KRNTKM-RELSWCKLTELYDDGKVNAVGVSN 123
+SLE LD +Y+DL L+H+P L ED N KM R+ +W L +L+ +GK+ ++GVSN
Sbjct: 94 ESLELLDRKYLDLVLVHYP--RPLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSN 151
Query: 124 FTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNS 183
+ H+E M S + P VNQ+E+HP++ + L +C ++ I QA+ G N +
Sbjct: 152 YEPHHIEE-MRSYITIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLGR---GNKT 207
Query: 184 LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMK 242
LL D + AL + T A V+L W ++ V+ K+V P + EN SL+ ++ +++ +
Sbjct: 208 LLGDSTMERIALCHKTTVANVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDDEFE 267
Query: 243 ALNQLS 248
+N L+
Sbjct: 268 KINGLN 273
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 116 bits (279), Expect = 6e-25
Identities = 67/195 (34%), Positives = 106/195 (54%), Gaps = 16/195 (8%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFT 125
KS++ L Y+DL+L+H P G + + R SW + + G+V GVSN+
Sbjct: 107 KSVKASGLGYIDLFLLHSPLGGR---------EARLTSWKAVEDAVLAGEVKMAGVSNYG 157
Query: 126 VAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLL 185
V HL+ +M + + P VNQ+E HP+ TQ + C+++ I ++AY + +
Sbjct: 158 VKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACEKYGIVIEAYAPL-----ARGMRM 212
Query: 186 NDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKAL 244
PV+ + A K VTPAQVL+ W++Q +PK+ E + EN + F++ EEDM+ L
Sbjct: 213 KHPVLTAVAKKYGVTPAQVLVRWSVQHGFVTLPKSTKKERLVENADVGRFELAEEDMEKL 272
Query: 245 NQLSEKNVKYAWDPS 259
+ L EK V WDP+
Sbjct: 273 DGLDEKLVT-DWDPT 286
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 116 bits (279), Expect = 6e-25
Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 16/204 (7%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP------GGAKLPA-EDKRNTKMRELS----WCKLTE 109
E +SL+ L L+YVDL L+H+P G K+P ED R+ S W + +
Sbjct: 120 EACLDESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEK 179
Query: 110 LYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQ 169
L GK A+GVSN+++A L+ L+ + +VPA NQVE HP+ Q L K+C I Q
Sbjct: 180 LPATGKTKAIGVSNWSIAFLDKLL-AKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQ 238
Query: 170 AYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN 229
AY G S +L D V S A + PAQV++ WA Q+ V +PK+V P I+ N
Sbjct: 239 AYSPLGS---SGGPVLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETN 295
Query: 230 RSLNFKIPEEDMKALNQLSEKNVK 253
L + +E+M LN+L ++ K
Sbjct: 296 GKL-IVLSDEEMLELNELHKQEGK 318
Score = 36.7 bits (81), Expect = 0.60
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 11/78 (14%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLEN 70
TF LN G +P IGLGT++ + V + V+ A++AGYR + SL
Sbjct: 13 TFKLNTGAEIPVIGLGTWQSAPGE-VAKAVESAIKAGYRHIV----------SMLTSLLT 61
Query: 71 LDLEYVDLYLIHFPGGAK 88
L L YV L+ ++ P AK
Sbjct: 62 LTLGYVALHPLYIPFLAK 79
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 115 bits (277), Expect = 1e-24
Identities = 66/205 (32%), Positives = 113/205 (55%), Gaps = 16/205 (7%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMRELSWCK----LTELY 111
EQA +SL+NL+++Y+DLYL+H+P G P + + N+K ++ + + +L
Sbjct: 88 EQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLV 147
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
GK A+G+SNF+ +E L+ES +VPAV Q+E HP+ Q+ ++ K I + Y
Sbjct: 148 KSGKTKAIGISNFSKGEMERLLESC-SIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQY 206
Query: 172 CSFGGTSCSNNS------LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
S G + + L+ DP + + K T AQV L W + + +V+ K+ P
Sbjct: 207 SSLGNQNEVYSGRERYGRLIEDPALAAIGTKYGKTGAQVALAWGITKGHSVLVKSKTPHR 266
Query: 226 IKENRSLNFKIPEEDMKALNQLSEK 250
I++N +F++ +EDMKA+ + +K
Sbjct: 267 IQQNFESDFELKQEDMKAIENIDKK 291
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 115 bits (277), Expect = 1e-24
Identities = 64/195 (32%), Positives = 107/195 (54%), Gaps = 14/195 (7%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
+D +QA + SL+ L L+YVDLYLIH+P P +D + +W +L L +
Sbjct: 79 NDDQHNPQQALETSLQKLQLDYVDLYLIHWPD----PKQDHYVS-----AWRELVTLKEQ 129
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G + ++GV NF + HL+ L++ G+ P VNQ+E HP Q L+ + HHI + S
Sbjct: 130 GLIRSIGVCNFHIPHLQRLIDET-GIAPTVNQIELHPLLQQRQLHAWNATHHIATE---S 185
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSL 232
+ + + + ++ A + TPAQ+++ W L + VIPK+V P I+EN
Sbjct: 186 WSPLAQGGKGVFDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIPKSVTPARIRENFEVF 245
Query: 233 NFKIPEEDMKALNQL 247
+FK+ +E++ A+ +L
Sbjct: 246 DFKLQKEELLAITKL 260
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 115 bits (276), Expect = 1e-24
Identities = 67/190 (35%), Positives = 108/190 (56%), Gaps = 7/190 (3%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGG-AKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
++A +L+ LEY+DL LIH P ++ + R+ K +W + E GKV ++
Sbjct: 88 KKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRHFKGNLENWRAMEEAVKAGKVRSI 147
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GVSNF +E ++ +N + PAVNQ+E H L +CK+ I ++AY +
Sbjct: 148 GVSNFLQEDIENIV-NNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAY-----SPL 201
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEE 239
S+ LLND +++ A K VTPAQ++L + +Q VIPK+ + +KEN ++NFKI +E
Sbjct: 202 SHGKLLNDDQIIAYAKKYNVTPAQLMLAFDMQLGCIVIPKSDNVTEMKENLNINFKISDE 261
Query: 240 DMKALNQLSE 249
D+ L ++ E
Sbjct: 262 DIAKLIKIKE 271
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAEQAYQKSLENL 71
+LNNG +P I LGT+ I +D V +VV A+ GYR F D+G+ E K + N
Sbjct: 8 ILNNGEKIPQIQLGTWLI-NNDEVNKVVRQAVNIGYRGFDTAKDYGN--ESGVGKGIWNS 64
Query: 72 DLEYVDLYL 80
D+E D++L
Sbjct: 65 DIERSDIFL 73
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 115 bits (276), Expect = 1e-24
Identities = 66/193 (34%), Positives = 105/193 (54%), Gaps = 15/193 (7%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A + SLE L L+YVDL+L+H+P +P E R + EL + G A+GV
Sbjct: 93 EALEHSLERLGLDYVDLFLMHWP----MPGEGSYVDAYRGM-----VELKEQGLAKAIGV 143
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SNF V HL+ L+ G+ P VNQ++ P + + F H I +A+ G +
Sbjct: 144 SNFKVHHLDDLI--TEGMTPEVNQIQLDPSRPRLEVRDFLDNHDIVTEAWSPLGRGA--- 198
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEED 240
+ +LN P V+ A K +TPA +L W L Q + IPK+ +PEH + N ++ ++ ++
Sbjct: 199 DGVLNAPAVLDAAKKHGITPAAAVLAWELNQGIVTIPKSANPEHQRTNLEAIGVELSAQE 258
Query: 241 MKALNQLSEKNVK 253
MKA++ L++ N K
Sbjct: 259 MKAIDALADPNAK 271
Score = 33.1 bits (72), Expect = 7.3
Identities = 21/77 (27%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 6 PIIPT-TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSD-HGSRAEQA 63
P PT T L+ G MP +G+GT+ ++ + V A+E GYR+ ++ +G+ E+A
Sbjct: 4 PTTPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVAS-AIEQGYRLVDTAEAYGN--EEA 60
Query: 64 YQKSLENLDLEYVDLYL 80
K++ + ++++
Sbjct: 61 VGKAVREAGPDRAEIFV 77
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 114 bits (275), Expect = 2e-24
Identities = 77/223 (34%), Positives = 115/223 (51%), Gaps = 23/223 (10%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFP-----------------GGAKLPAEDKRNTK 98
H E+A SL++L +Y+DLYL+H+P GG + +ED
Sbjct: 88 HPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHPVESEDLSRDF 147
Query: 99 MRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLY 158
M ++ + E+ GKV +GVSNF + +++ + P VNQVE + L
Sbjct: 148 MA--TYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEA-SIKPVVNQVEVNLGVHNEELR 204
Query: 159 KFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIP 218
+ H +TLQAY FG SL DPVVV A + +TPAQVLL W L +D+ I
Sbjct: 205 NYAHAHGVTLQAYSPFGSNQNVAKSL-EDPVVVDVAQRNNITPAQVLLAWTLGRDIIPIS 263
Query: 219 KAVHPEHIKEN-RSLNFKIPEEDMKAL-NQLSEKNVKYAWDPS 259
K+V PE I+EN R L+ ++ EE++K L N+ + ++ DP+
Sbjct: 264 KSVTPERIEENFRVLDIQLAEEEIKHLTNEALSRPIERTVDPT 306
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 114 bits (274), Expect = 2e-24
Identities = 65/194 (33%), Positives = 114/194 (58%), Gaps = 14/194 (7%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVN 117
+R ++ ++LE L +EY++L+LIH+P +PA++ + +W EL G +
Sbjct: 84 ARTLVSFNETLERLGVEYLELFLIHWP----IPAKN-----LYVETWEASIELEASGLIR 134
Query: 118 AVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
++GVSNFT H+E L+E G+VPAVNQ+E HP++ Q + + + I +Q+Y FG
Sbjct: 135 SIGVSNFTCQHIERLIEDT-GVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGSN 193
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKI 236
++L + VV+ A + + +PAQ++L W LQQ + +P+ + EN + +F++
Sbjct: 194 GA---AVLRNAVVMVLARRHDHSPAQIVLRWHLQQGLTPLPRTTNGARFSENVDVWDFEL 250
Query: 237 PEEDMKALNQLSEK 250
EE+MK L L+ +
Sbjct: 251 SEEEMKLLASLNTR 264
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 114 bits (274), Expect = 2e-24
Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 16/215 (7%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP------GGAKLPAEDKRNTKMREL 102
+++ S + E A +L+ L LEY+DLYLIH+P G K N K +L
Sbjct: 74 KLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKL 133
Query: 103 --------SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQ 154
+W + +L D GKV A+GVSNF ++ ++E+ G+ P+VNQ+E HP Q
Sbjct: 134 DLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEAT-GVTPSVNQIERHPLLLQ 192
Query: 155 SSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDV 214
L K +I + AY G + L+ P + A K TPAQVL+ WA+
Sbjct: 193 PELIAHHKAKNIHITAYSPLGNNTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGH 252
Query: 215 AVIPKAVHPEHIKENRSLNFKIPEEDMKALNQLSE 249
+VIPK+V P I EN + +ED+ A+++L E
Sbjct: 253 SVIPKSVTPSRIGENFK-QVSLSQEDVDAVSKLGE 286
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 113 bits (273), Expect = 3e-24
Identities = 71/196 (36%), Positives = 107/196 (54%), Gaps = 11/196 (5%)
Query: 54 SDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
SDHG + ++A +SL +L L+Y+D+YLIH+P + + ++ SW + E
Sbjct: 84 SDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMR---DHWAEINAESWRAMEEAVR 140
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
GK+ A+GVSNF HL+ LME+ + P VNQ+ +P QS + K+ + +AY
Sbjct: 141 AGKIRAIGVSNFRKHHLDALMETAE-IKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYS 199
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
G LL + VV A + AQVL+ W+LQ +PK+VHPE+IK N +
Sbjct: 200 PLG-----TGGLLGNEVVKEVAANYGKSTAQVLIRWSLQHGFLPLPKSVHPEYIKANADV 254
Query: 233 -NFKIPEEDMKALNQL 247
+F+I EDM L+ L
Sbjct: 255 FDFEISPEDMAKLDNL 270
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 113 bits (273), Expect = 3e-24
Identities = 71/201 (35%), Positives = 105/201 (52%), Gaps = 16/201 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFP----GGAKLPAEDKRNTKMREL--------SWCK 106
R E+ SLE L L+YVD+ LIH+P P R R++ +W +
Sbjct: 115 RVEENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQ 174
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
+ + GK ++GVSNF++ +LE L++ +VPAVNQVE HP Q L +FCK+++I
Sbjct: 175 MEAVLKTGKTKSIGVSNFSIPYLEELLKEAE-VVPAVNQVELHPLLPQLELMEFCKKNNI 233
Query: 167 TLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
+ A+ FG LL + +VVS A K +P +L + + VIPK+V I
Sbjct: 234 VMTAFSPFGSV---GGPLLKNELVVSLADKYNTSPGGILTSYHIGNGTVVIPKSVTNSRI 290
Query: 227 KENRSLNFKIPEEDMKALNQL 247
EN + +ED+KALN L
Sbjct: 291 VENGKSAVTLSQEDLKALNDL 311
Score = 35.1 bits (77), Expect = 1.8
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
F LNNG +P+IGLGT++ ++ V E GYR
Sbjct: 34 FTLNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYR 71
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 113 bits (272), Expect = 4e-24
Identities = 68/195 (34%), Positives = 107/195 (54%), Gaps = 24/195 (12%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGK 115
H EQA +L+NL L YVDLYL+H+P +++ + +L GK
Sbjct: 69 HPDDVEQACDITLKNLQLSYVDLYLMHWP-----------------MAYQAMEKLVTSGK 111
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
A+G+SNF++ ++ ++E + PA QVE HP TQ L +FCK+H++T+ AY G
Sbjct: 112 CKAIGLSNFSMKMMKRVIEKAT-IQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLG 170
Query: 176 G-----TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN- 229
+ L+ DP+V A K +PAQ+L+ + L++ + IPK+V P I+ N
Sbjct: 171 APDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPKSVTPSRIQANF 230
Query: 230 RSLNFKIPEEDMKAL 244
+LNF++ ED+K L
Sbjct: 231 EALNFELDPEDLKTL 245
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 113 bits (272), Expect = 4e-24
Identities = 68/197 (34%), Positives = 108/197 (54%), Gaps = 16/197 (8%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
+DH +A A + SL+ L+++Y+D+YL+H PG + AE + +W L E D
Sbjct: 97 ADH-DKAAAAIEDSLKKLNVDYMDMYLMHSPG--TMGAEKRLE------AWKALEEAVDA 147
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
GK+ +GVSNF V L+ L+ +N + PAVNQ+E HP++ L + C I +QAY
Sbjct: 148 GKIKTIGVSNFDVEELDHLL-ANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAY-- 204
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
+ + L+ P + + A K TPAQ+LL W L ++PK++ I+ N L
Sbjct: 205 ---SPMAQGQALDRPEIKTIASKHGKTPAQILLKWGLTHGNIILPKSLTKHRIESNAQLF 261
Query: 233 NFKIPEEDMKALNQLSE 249
+F++ +DM L+ L E
Sbjct: 262 DFELDSDDMDVLDNLDE 278
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 113 bits (272), Expect = 4e-24
Identities = 74/227 (32%), Positives = 112/227 (49%), Gaps = 15/227 (6%)
Query: 30 IRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP----G 85
IR+S + + + + AP D E A K+L++L + Y+DLYL+H+P G
Sbjct: 61 IRKSGVPREEIFITGKLWNTKHAPED----VEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 86 GAK-LPAEDKRNTKMRELSWCK----LTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV 140
G K P D + + + + +L GKV A+GVSNF + LE L+ +V
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELL-GQVSVV 175
Query: 141 PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVT 200
PAVNQ+E HPY Q L +FC+ I ++AY G ++DP+V A +L +
Sbjct: 176 PAVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGNNQTGEPRTVDDPLVHRVAGELSLD 235
Query: 201 PAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEEDMKALNQL 247
P +L W +Q+ V+ K+V P I N + +PE LN L
Sbjct: 236 PGPLLASWGVQRGTVVLSKSVTPARIAANLRVR-ALPEGAFAQLNSL 281
Score = 35.9 bits (79), Expect = 1.0
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 8 IPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+P+ F +N G +P++G GT++ + + V V+ AL GYR
Sbjct: 3 LPSHFTINTGAKIPAVGFGTWQAKPLE-VENAVEVALREGYR 43
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 112 bits (270), Expect = 7e-24
Identities = 68/210 (32%), Positives = 115/210 (54%), Gaps = 10/210 (4%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHF-----PGGAKLPAEDKRNTKMRELS 103
+++ H E A QK+L+NL LEY+D+YLIH+ PG + P + + +M S
Sbjct: 86 KLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGNYEYPIKKEDFLQMDYKS 145
Query: 104 -WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
W + E G A+GVSNF+ L ++ +N + PAVNQVE +P + Q L +FCK
Sbjct: 146 VWEAMEECQKLGLTKAIGVSNFSCKKLSDVL-ANAKVPPAVNQVEVNPCWQQKQLTEFCK 204
Query: 163 QHHITLQAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
+ I + AY + G GT N ++ V+ A T AQV L WA +Q + V+ K+
Sbjct: 205 SNGILVVAYAALGAVGTFYGTNRVMGSEVLNEIARIRGNTVAQVCLRWAYEQGIGVLVKS 264
Query: 221 VHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
+ E +++N + N+ + +++ K ++++ +
Sbjct: 265 FNKERMEQNLQIFNWTLSDDESKKISEIPQ 294
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 112 bits (269), Expect = 1e-23
Identities = 77/217 (35%), Positives = 114/217 (52%), Gaps = 21/217 (9%)
Query: 56 HGSRA---EQAYQKSLENLDLEYVDLYLIHFPG-----GAKLPAEDK----RNTKMRELS 103
HG+RA E+ + SL++L LEYVDLY +H P ED T
Sbjct: 84 HGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDHVAL 143
Query: 104 WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQ 163
W + E+Y+ G +G+SNF ++ +++ N + PA Q+E H Y Q L KFCK
Sbjct: 144 WKAMEEVYEAGLARNIGLSNFNQRQIQRILD-NCQIKPANLQIENHIYLQQPELVKFCKA 202
Query: 164 HHITLQAYCSFGGTSCSN------NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVI 217
+ IT+ AY G LL++PVV A KL +PAQVLL LQ+ ++ I
Sbjct: 203 NGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKDIAEKLGKSPAQVLLRHLLQRGISTI 262
Query: 218 PKAVHPEHIKENRSL-NFKIPEEDMKALNQLSEKNVK 253
PK+ +P +++N L F+I + DM LNQL ++N++
Sbjct: 263 PKSTNPTRLRDNIDLFGFEIDDSDMVRLNQL-DQNIR 298
Score = 34.7 bits (76), Expect = 2.4
Identities = 16/34 (47%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 16 NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
NG MP++G GT+R + V + ++ ALEAGYR
Sbjct: 11 NGTTMPALGFGTWRASDEE-VEKALNEALEAGYR 43
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 112 bits (269), Expect = 1e-23
Identities = 76/224 (33%), Positives = 117/224 (52%), Gaps = 20/224 (8%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMRELS 103
++++ S + + SL L+L+YVDLYLIHFP G LP ++ N +
Sbjct: 84 KLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVD 143
Query: 104 WCKLTELY----DDGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSL 157
C E D G ++GVSNF LE ++ + GL P NQVE H Y QS L
Sbjct: 144 LCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL-NKPGLKYKPVCNQVECHLYLNQSKL 202
Query: 158 YKFCKQHHITLQAYCSFGGTS---CSNNS---LLNDPVVVSTALKLEVTPAQVLLVWALQ 211
+CK + I L AY + G C N LL+DPV+ + A K + TPA + L + L
Sbjct: 203 LAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLD 262
Query: 212 QDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSEKNVKY 254
+ + + K+ + E I+EN + +F++ +DMK L+ L ++N++Y
Sbjct: 263 RGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGL-DRNLRY 305
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 111 bits (268), Expect = 1e-23
Identities = 68/189 (35%), Positives = 102/189 (53%), Gaps = 14/189 (7%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A +A+ SL+ L L+YVD+Y+IH+P D R+T +W +L D+G +
Sbjct: 98 ALKAFDNSLKLLQLDYVDMYMIHWP-----TPFDWRSTD----TWKAFVKLRDEGMARTL 148
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GV NF A L+ L E G PAVNQ+E HP + Q + FCK+H I ++AY +
Sbjct: 149 GVCNFMPADLKRLHEET-GAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGAD 207
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
N D + A EV+PAQV+L W ++ +IPK+VH + KEN +L F +
Sbjct: 208 LN---AGDGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTA 264
Query: 239 EDMKALNQL 247
++ A++ L
Sbjct: 265 DEHAAIDAL 273
Score = 35.1 bits (77), Expect = 1.8
Identities = 18/36 (50%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
L +G +P +GLG RI +V VV+ ALEAGYR
Sbjct: 16 LKDGHSIPQVGLGVLRIDDEGVV-PVVESALEAGYR 50
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 111 bits (268), Expect = 1e-23
Identities = 67/195 (34%), Positives = 111/195 (56%), Gaps = 13/195 (6%)
Query: 54 SDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRN-TKMRELSWCKLTELY 111
+DHG A++A SL L L+YVDLYLIH+P PA + N ++ +W + E Y
Sbjct: 85 ADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPN----PAAMRDNWEQLNADTWRAMEEAY 140
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
K A+GVSNF HL+ L+++ +VPAVNQ+ +P + + + ++H I +AY
Sbjct: 141 TARKARAIGVSNFRPKHLDALLKTAK-VVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAY 199
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
G + + P + + A K + + AQV+L W+LQ +PK+VH + I++N
Sbjct: 200 SPLG-----TGKIFSIPELKTLADKYDKSVAQVVLRWSLQHGFLPLPKSVHADRIEQNTE 254
Query: 232 L-NFKIPEEDMKALN 245
L +F++ ++DMK ++
Sbjct: 255 LFDFELSDDDMKVID 269
Score = 37.9 bits (84), Expect = 0.26
Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR-MFAPSDHGSRAEQAYQKSLE 69
T+ LNNG +P +G GT++ + V AL+AGYR + + +G+ E++ K++
Sbjct: 10 TYTLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGN--EESVGKAIA 67
Query: 70 NLDLEYVDLYL 80
+ + DL++
Sbjct: 68 DSGVAREDLFV 78
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 111 bits (268), Expect = 1e-23
Identities = 73/199 (36%), Positives = 108/199 (54%), Gaps = 14/199 (7%)
Query: 54 SDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
SD+G A+ KS L ++ +DL L+H P LP+ R ++ L +L
Sbjct: 94 SDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP----LPSAFDRTLG----AYRALEKLLA 145
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
DGKV A+GVSNF HL L+ +VPAVNQ+E HPY+ Q +L + +H I QA+
Sbjct: 146 DGKVRAIGVSNFMPEHLTRLLTET-SIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWS 204
Query: 173 SFGGTSC---SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN 229
GG + S L DPV++ A + + AQV+L W LQ+ +VIPK+ P I EN
Sbjct: 205 PIGGITFYRGGEKSTLEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIPKSTKPARIAEN 264
Query: 230 RSL-NFKIPEEDMKALNQL 247
+ +F++ E + A++ L
Sbjct: 265 FDVFDFELSGEQIAAIDAL 283
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 111 bits (267), Expect = 2e-23
Identities = 71/214 (33%), Positives = 119/214 (55%), Gaps = 24/214 (11%)
Query: 57 GSRAEQA---YQKSLENLDLEYVDLYLIHFPGGAKL------PAEDKRNTKMRELS---- 103
G+RAE + SL+NL LEY+DLYLIH P G + P ++ + ++ +
Sbjct: 84 GNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNSTNHVE 143
Query: 104 -WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
W ++ + G+ A+G+SNF ++ ++ +++ N + ++ Q+E H Y+ Q L KFCK
Sbjct: 144 IWAEMEKQVKCGRTKAIGLSNFNISQIKRILK-NTKMKISMLQIELHVYFQQKELVKFCK 202
Query: 163 QHHITLQAYCSFGGTSCSN--------NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDV 214
Q +I + AY G S + +L + VV+ A K + + AQ+LL + +Q +
Sbjct: 203 QENIPITAYSPLGSRSLIKLLNKTEEISDMLQNDVVMEIAKKYKKSSAQILLRYIVQNGI 262
Query: 215 AVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQL 247
VIPK+++P+ IKEN L +++I EDMK L L
Sbjct: 263 VVIPKSINPQRIKENIQLFDWEINPEDMKKLYNL 296
Score = 37.1 bits (82), Expect = 0.45
Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 1/39 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T +L NG +MP IG GT++ ++ ++ ++ ALEAGYR
Sbjct: 5 TILLPNGELMPIIGFGTWQAQEKEL-EDALNIALEAGYR 42
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 111 bits (267), Expect = 2e-23
Identities = 76/222 (34%), Positives = 116/222 (52%), Gaps = 19/222 (8%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKR-----NTK 98
+++ H E A +K+L +L LEY+DLYL+H+P G P +T
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 99 MRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLY 158
+E +W L L G V A+G+SNF ++ ++ S + PAV QVE HPY Q+ L
Sbjct: 140 YKE-TWKALEALVAKGLVQALGLSNFNSRQIDDIL-SVASVRPAVLQVECHPYLAQNELI 197
Query: 159 KFCKQHHITLQAYCSFGGTSCSNNS-----LLNDPVVVSTALKLEVTPAQVLLVWALQQD 213
C+ + + AY G + + LL +PVV++ A K +PAQ+LL W +Q+
Sbjct: 198 AHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRK 257
Query: 214 VAVIPKAVHPEHIKEN-RSLNFKIPEEDMKALNQLSEKNVKY 254
V IPK++ P I +N + +F E+MK LN L+ KN +Y
Sbjct: 258 VICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALN-KNWRY 298
Score = 32.7 bits (71), Expect = 9.7
Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+L+ G MP IGLGT++ V V YAL GYR
Sbjct: 7 LLHTGQKMPLIGLGTWKSEPGQ-VKAAVKYALSVGYR 42
>UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os05g0456200 protein -
Oryza sativa subsp. japonica (Rice)
Length = 229
Score = 111 bits (266), Expect = 2e-23
Identities = 71/213 (33%), Positives = 105/213 (49%), Gaps = 20/213 (9%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLEN 70
+FVLN +PS+GLGT++I V + A++ GYR S ++ +
Sbjct: 4 SFVLNTNAAIPSVGLGTWQISPG-AVQDAIRAAVQVGYRHIDCSPQYGNQKEVHGP---- 58
Query: 71 LDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLE 130
+ G KL E+ + +W + +LYD GK A+GVSNF+ LE
Sbjct: 59 ----------VRAKKGTKLSVENYLKPDI-PATWQAMEKLYDSGKARAIGVSNFSCKKLE 107
Query: 131 GLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN---SLLND 187
L+ + PAVNQVE HP + Q L K C+ + L AY G N ++L+
Sbjct: 108 DLLNVAR-VPPAVNQVECHPVWQQGKLRKLCQSKGVHLSAYAPLGSPGSPGNDGPNVLSH 166
Query: 188 PVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
P V+S A KL+ +PAQV L W +Q +V+PK+
Sbjct: 167 PTVISIAKKLQKSPAQVALRWGIQMGQSVLPKS 199
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 111 bits (266), Expect = 2e-23
Identities = 76/208 (36%), Positives = 113/208 (54%), Gaps = 20/208 (9%)
Query: 65 QKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMRELSWCKLTELY----DDGK 115
+++L L L+YVDLY+I P G P ++ + + C E D G
Sbjct: 103 ERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGL 162
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
V ++GVSNF LE L+ + GL P NQVE HPY+TQ L KFC+QH I + AY
Sbjct: 163 VKSLGVSNFNRRQLE-LILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSP 221
Query: 174 FGGT------SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIK 227
G + + S+ LL D ++ S + T AQ++L + +Q+ V VIPK+ + E IK
Sbjct: 222 LGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIK 281
Query: 228 EN-RSLNFKIPEEDMKALNQLSEKNVKY 254
EN + +F + EE+MK + L+ KNV++
Sbjct: 282 ENFQIFDFSLTEEEMKDIEALN-KNVRF 308
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 110 bits (265), Expect = 3e-23
Identities = 71/198 (35%), Positives = 113/198 (57%), Gaps = 21/198 (10%)
Query: 53 PSDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
PS+ G S A + ++S++ LD+ YVDL+LIH P + A ++ L L
Sbjct: 84 PSEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRPGNIIA-----------AYDALLTLK 132
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
++G + +VGVSNF V HLE L ++ PA+NQ+E +P++ Q + K+C +H IT++ Y
Sbjct: 133 EEGLIRSVGVSNFGVHHLEELRKAGCR-TPAINQIEINPFWRQEEIIKYCNKHGITVEGY 191
Query: 172 CS-FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
F G C + PV+V + + T AQ+++ W++Q+ IPK+ +PE I EN
Sbjct: 192 APVFRG--CK----FDHPVLVEMSERYGKTVAQIMIRWSVQKQYITIPKSSNPERILENA 245
Query: 231 SL-NFKIPEEDMKALNQL 247
+ +F I E+DMK L L
Sbjct: 246 QVFDFVISEKDMKNLVSL 263
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 110 bits (264), Expect = 4e-23
Identities = 68/204 (33%), Positives = 113/204 (55%), Gaps = 17/204 (8%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A +A+Q S + L +E+VDLYLIH+P +P++ + +W + +LY + ++ A+
Sbjct: 90 AHEAFQNSRKALGVEFVDLYLIHWP----VPSQG-----LYTEAWKAMEKLYANSQIRAI 140
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GVSNF HL+ L+ + +VPAVNQVE HP + Q L C++ I ++AY G
Sbjct: 141 GVSNFLGEHLDTLLPAAD-VVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLG---- 195
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPE 238
+ LN V A K + TPAQ++L W L Q VIPK+ + ++EN ++ ++
Sbjct: 196 -QGADLNATAVKDLAGKYDATPAQIVLAWHLAQGTIVIPKSADSKRMRENLGAVAVELSP 254
Query: 239 EDMKALNQLSEKNVKYAWDPSIVA 262
++ ++ L E + DP++ A
Sbjct: 255 AELSEISAL-ESGARAGADPAVAA 277
Score = 37.5 bits (83), Expect = 0.34
Identities = 15/36 (41%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LNNG+ +P +G G +++ + ++V+ ALEAGYR
Sbjct: 14 LNNGVKIPQLGFGVFQVPPEE-TQRIVEDALEAGYR 48
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 109 bits (263), Expect = 5e-23
Identities = 67/213 (31%), Positives = 113/213 (53%), Gaps = 10/213 (4%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHF-----PGGAKLPAEDKRNTKMR-EL 102
+++ H + ++SL NL +EYVDLYL+H+ PG LP + + E
Sbjct: 86 KLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPVKREDAVPFDFEG 145
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
W + E + G A+GVSNFT HL+ L+ + + PAVNQVE +P + Q ++ ++C
Sbjct: 146 VWRAMEECHRLGLAKAIGVSNFTTKHLDKLL-AVATIPPAVNQVEMNPVWQQRTVREYCA 204
Query: 163 QHHITLQAYCSFGGTSC--SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
I + AY GG + N ++ PV+ A + AQV L W +Q V IPK+
Sbjct: 205 AKGIRVAAYSPLGGQNWIGEGNDVMESPVLADIARARGKSIAQVSLRWIHEQGVTPIPKS 264
Query: 221 VHPEHIKENRSL-NFKIPEEDMKALNQLSEKNV 252
+ E +K+N + ++++ +ED ++Q+ +K +
Sbjct: 265 YNKERLKQNLEIFDWELTKEDRLKISQIPQKKI 297
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 109 bits (263), Expect = 5e-23
Identities = 72/216 (33%), Positives = 114/216 (52%), Gaps = 21/216 (9%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAK---------LPAEDK----RNTKMR 100
SDHG E A + SLE L ++Y+DLYL+H+P K L EDK T
Sbjct: 81 SDHGHVVE-ACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISL 139
Query: 101 ELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKF 160
+ +W + + G V ++G+SN+ + + + + PAV+Q E HPY+ + SL KF
Sbjct: 140 QQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSK-IKPAVSQFETHPYFQRDSLVKF 198
Query: 161 CKQHHITLQAYCSFGGTSCSNN-----SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVA 215
C +H + A+ GG + + + S L+DPV+ A K + AQ+ L W +Q+ A
Sbjct: 199 CMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTA 258
Query: 216 VIPKAVHPEHIKEN-RSLNFKIPEEDMKALNQLSEK 250
VIPK+ + +KEN L F++ +EDM+ + + K
Sbjct: 259 VIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRK 294
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 109 bits (262), Expect = 7e-23
Identities = 75/211 (35%), Positives = 115/211 (54%), Gaps = 22/211 (10%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAED--KRNTK------MREL--SWCKLTELYD 112
A +K+L L ++YVDLYLIH P K PAE+ +N +L +W L E D
Sbjct: 120 ALEKTLSFLQMDYVDLYLIHMPMSFK-PAEELFPKNEDGTCAFDQPDLLQTWQALEECRD 178
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
G V ++GVSNF LE ++ + GL P NQ+E HPY Q + +FCK I + A
Sbjct: 179 AGLVKSIGVSNFNRRQLEMIL-NKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVA 237
Query: 171 YCSFGGTSC------SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
Y G S LL DPV++S K +PAQV + + +Q+ I K+ +P+
Sbjct: 238 YGVLGSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRYMIQRGCVAIAKSFNPD 297
Query: 225 HIKENRSL-NFKIPEEDMKALNQLSEKNVKY 254
+K+N + +F++ +E+M A++ L+ KN++Y
Sbjct: 298 RMKQNLEVFDFQLSQEEMAAIDGLN-KNMRY 327
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 109 bits (262), Expect = 7e-23
Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 29/218 (13%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP-------------------GGAKLPAEDKRNTKMRE 101
E A ++S+++L L+Y+DLYL+HFP A+ PA + + E
Sbjct: 94 EAACRRSMDDLGLDYIDLYLVHFPIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSE 153
Query: 102 LSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
+W + +L + G V +GV N++ L LM S + PA+ Q+E HPY TQ +L +
Sbjct: 154 -TWGAMEQLVESGLVRQIGVCNYSAVLLHDLM-SYARIKPAMLQIESHPYLTQEALLRTA 211
Query: 162 KQHHITLQAYCSFGGTSC-------SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDV 214
+ +++ + A+ G S +N+++L DP V++ A + VT AQV+L W +Q+
Sbjct: 212 RSYNMAVTAFSPLGSLSYVELNMAGANDTVLTDPSVLAAAQRNGVTAAQVVLRWGIQRGT 271
Query: 215 AVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSEKN 251
AVIPK +P+ + EN +L F + +E+M A++ L++ +
Sbjct: 272 AVIPKTSNPQRLIENLTLTEFTLNDEEMDAISALNQNH 309
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 109 bits (262), Expect = 7e-23
Identities = 69/203 (33%), Positives = 108/203 (53%), Gaps = 16/203 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDK------RNTKMRELSWCKL 107
R E A++ SL+ L L+Y+DLYLIH P G + P + +RE +W L
Sbjct: 95 RVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRE-TWSAL 153
Query: 108 TELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHIT 167
L D G+ A+G+S+ ++ L + E+ + PAV QVE HPY ++ L +FCK++ I
Sbjct: 154 ENLVDRGRCRAIGLSDISMDRLAPIYEAAR-IKPAVVQVESHPYLPETELLEFCKRNGIV 212
Query: 168 LQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIK 227
L A+ G LL DPV+ S + ++ T AQVLL WA+Q+ A++ K
Sbjct: 213 LLAFAPLG--HGMRPGLLEDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTPRSAARAK 270
Query: 228 ENRSLNFKIPEEDMKALNQLSEK 250
EN ++ +PEE +N++ +
Sbjct: 271 ENFDIS-PLPEEAFNEINRIQTR 292
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 109 bits (262), Expect = 7e-23
Identities = 71/190 (37%), Positives = 102/190 (53%), Gaps = 15/190 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
RA SL+ L L+YVDL LIH+P LP D+ + +W L DGKV +
Sbjct: 86 RAVAGLDGSLKRLGLDYVDLLLIHWP----LPRRDEFIS-----TWKTFERLQADGKVRS 136
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF AHLE LM + +VPAVNQ++ P T+ + ++H I ++Y G S
Sbjct: 137 IGVSNFKPAHLERLMAACD-VVPAVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGAGS 195
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
LLN PV+ A K TP Q++L W ++Q + IPK +P+ +KEN + F +
Sbjct: 196 ----DLLNAPVLGRIAQKHGKTPGQIVLRWHVEQGLVAIPKTANPQRMKENLDIFGFTLD 251
Query: 238 EEDMKALNQL 247
+D A+ L
Sbjct: 252 ADDTSAIATL 261
Score = 33.1 bits (72), Expect = 7.3
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LN+G +P IGLGT+ + + VV+ A+E GYR
Sbjct: 9 LNDGHRIPQIGLGTWPLDDHQVAAAVVN-AVEGGYR 43
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 109 bits (262), Expect = 7e-23
Identities = 67/190 (35%), Positives = 98/190 (51%), Gaps = 9/190 (4%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPA--EDKRNTKMRELSWCKLTELYDDGKVNAV 119
+A +L +L + Y+DLYLIH+P K + + E W +L DG V +
Sbjct: 94 EALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQPDAEASIAEC-WSELERCVADGLVRHI 152
Query: 120 GVSNFTVAHLEGLMESNHGLV-PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
GVSNF A L L + + PA NQ+E HP ++ SL K+ + +T+ AY
Sbjct: 153 GVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGLTVTAYSPLA--- 209
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
L + ++V A K VTPAQV+L W +Q+DV VIPK+ + I N L F++
Sbjct: 210 -QGGELFENEILVGLAKKYGVTPAQVVLRWNVQRDVVVIPKSTSAKRIASNADLFGFELS 268
Query: 238 EEDMKALNQL 247
+EDM A+ L
Sbjct: 269 DEDMDAMKVL 278
Score = 37.1 bits (82), Expect = 0.45
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
Query: 9 PTTFVLN--NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR---MFAPSDHGSRAEQA 63
P+T ++N NG+ +P +GLGT++ R +++ V D AL AGY A + S +A
Sbjct: 3 PSTILVNDANGLRIPRVGLGTWKARPNEVRDAVRD-ALGAGYAHVDCAAAYANESEVGEA 61
Query: 64 YQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
+++ E D + D+++ +KL + +R +RE L +L
Sbjct: 62 LREAFERGDAKREDVFVT-----SKLWNDRRRPRDVREALMTTLNDL 103
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 108 bits (260), Expect = 1e-22
Identities = 65/195 (33%), Positives = 103/195 (52%), Gaps = 15/195 (7%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGK 115
H +A Q+SL +L+Y DLYLIH+P P +D + +W L E G
Sbjct: 84 HYDKAVTTIQESLYRANLDYYDLYLIHWPN----PIQD-----IYVEAWQALIEAKRRGY 134
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
+ ++GV NF HLE L + G +P +NQ+E HP++ Q K+ ++H I +++
Sbjct: 135 IRSIGVCNFLPEHLERLKQET-GELPTINQIELHPFFNQEDQRKWHQEHQIATESWSPLA 193
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
T N +L+ PV+ A T +Q++L W Q D IPK+ P EN S+ +F
Sbjct: 194 RT----NDVLDHPVLQKLASNHNRTVSQIILRWHYQLDAIAIPKSATPSRQLENISIFDF 249
Query: 235 KIPEEDMKALNQLSE 249
++ +E+M +NQLS+
Sbjct: 250 ELSDEEMSIINQLSK 264
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 108 bits (260), Expect = 1e-22
Identities = 74/220 (33%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP----GGAKLP---AED--KRNTKM 99
+++ S H A Q +L+NL L+Y+DLYLIH P G +LP AE +
Sbjct: 81 KLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEG 140
Query: 100 RELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYK 159
+ +W + L G A+GVSNF+V L L+E+ +VPA NQVE HPY Q L +
Sbjct: 141 VQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETA-SIVPACNQVELHPYLPQEKLKE 199
Query: 160 FCKQHHITLQAYCSFG--GTSCSNNSL------LNDPVVVSTALKLEVTPAQVLLVWALQ 211
FC I L AY G G L + +PV+ A K + A+VLL W +Q
Sbjct: 200 FCDSKGILLTAYSPLGNPGRLVPKERLEREPKVMEEPVIKEIAAKHNCSVARVLLRWGIQ 259
Query: 212 QDVAVIPKAVHPEHIKENRS-LNFKIPEEDMKALNQLSEK 250
+ V+PK+ +H+ +N S L + +++M A+ ++ +
Sbjct: 260 RGYPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTR 299
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 108 bits (259), Expect = 2e-22
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 35/266 (13%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSD-HGSRAE--QAYQKS 67
T +LN+G +P +G G ++I D Q V AL+ GYR + +G+ AE Q S
Sbjct: 14 TILLNDGREIPQLGFGVFQIEPGD-TAQAVKTALDLGYRHIDTAQMYGNEAEVAQGIADS 72
Query: 68 LENLDLEYVDLYL---IHFPGGAKLPAEDKRNTKMR---EL-----------------SW 104
D +V L H P A+ +D K+R +L +W
Sbjct: 73 GVPRDEIWVTSKLNNGFHEPDAARKAVDDSVE-KLRGPIDLYLIHWPLPTLYGGDFVSTW 131
Query: 105 CKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQH 164
L E GK+ ++GVSNF V HL+ L + +VPAVNQ+E HPY+ + + C +H
Sbjct: 132 KVLEEARAAGKLRSIGVSNFQVNHLQRLAQ-EATVVPAVNQIEVHPYFGNEEVRRHCGEH 190
Query: 165 HITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
I ++A+ + + +L+DP V + A +L +PAQV+L W +++ V PK+V P
Sbjct: 191 QIGVEAW-----SPIAQGKVLDDPTVTAVANRLGKSPAQVVLRWHVERGDIVFPKSVTPS 245
Query: 225 HIKENRSL-NFKIPEEDMKALNQLSE 249
++EN +L +F++ EED+ ++ L +
Sbjct: 246 RMEENFALFDFELTEEDLALISALDK 271
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 108 bits (259), Expect = 2e-22
Identities = 63/191 (32%), Positives = 104/191 (54%), Gaps = 8/191 (4%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+A + + +++ N LE +DLYLIH P D TK W + E+Y+ G+ A
Sbjct: 88 KALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADY--TKENIEVWKAMEEIYESGRCRA 145
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF+V+ L+ +ME N + P VNQ+ + +TQ + FC+ + I ++AY +
Sbjct: 146 IGVSNFSVSDLKAVME-NAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAY-----SP 199
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPE 238
+ +L + + A K T QV + + LQ+ V +PK+ H I +N ++F+I
Sbjct: 200 LATGKILENAEIQKIADKYGKTLPQVCICYCLQKGVLPLPKSTHEAFILQNADVDFEISS 259
Query: 239 EDMKALNQLSE 249
EDM+ L+QL E
Sbjct: 260 EDMQYLDQLKE 270
Score = 50.4 bits (115), Expect = 5e-05
Identities = 28/88 (31%), Positives = 49/88 (55%), Gaps = 6/88 (6%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLEN 70
TFVL NG+ +P IGLGT+++ + V +AL+ GYR + + E++ K++ +
Sbjct: 7 TFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYR-HIDTAYAYHNEESVGKAVRD 65
Query: 71 LDLEYVDLYLIHFPGGAKLPAEDKRNTK 98
++ D+++ +KLPAE K K
Sbjct: 66 SGIDRRDIFVT-----SKLPAEIKSYDK 88
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 108 bits (259), Expect = 2e-22
Identities = 74/195 (37%), Positives = 104/195 (53%), Gaps = 17/195 (8%)
Query: 55 DHGSRAE-QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
DHG A +A+ S+ NL +EYVDLYLIH+P R E S+ + LY +
Sbjct: 98 DHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCA--------RRGLFTE-SYRAMETLYRE 148
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G++ A+GVSNF AHLE L+E+ +VPAVNQ+E HP+ Q L + + I +A+
Sbjct: 149 GRIRAIGVSNFQPAHLEHLLETAE-VVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSP 207
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
G +L DPVV+ A + AQ++L W +Q VIPKA I+EN +
Sbjct: 208 LG-----RGQVLADPVVLELAAAHRRSAAQIILRWHVQLGNVVIPKASSYARIRENLDVF 262
Query: 233 NFKIPEEDMKALNQL 247
F + +M AL L
Sbjct: 263 GFTLDPAEMAALAAL 277
Score = 37.9 bits (84), Expect = 0.26
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
LNNG+++ +G G Y++ +D +V ALEAGYR F
Sbjct: 9 LNNGVLIDQLGFGLYKVPPAD-AAGLVTMALEAGYRHF 45
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 108 bits (259), Expect = 2e-22
Identities = 67/207 (32%), Positives = 117/207 (56%), Gaps = 19/207 (9%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAKLPAE-------------DKRNTKMRELSWCKLTELY 111
+ S ENL ++Y+DL+L+H+P A+ A+ +K T+ E +W + EL
Sbjct: 107 KNSCENLKVDYIDLFLVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELV 166
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
D G V A+GVSN+T+ L+ L+E + PAVNQ+E HP+ + L +FC Q+ I +AY
Sbjct: 167 DSGIVKAIGVSNWTIPGLKQLLEFAR-IKPAVNQIEIHPFLPNTELVEFCFQNDILPEAY 225
Query: 172 CSFGGTS---CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKE 228
G + + + ++P + + A + + AQVLL W L++ V+PK+ P I+
Sbjct: 226 SPLGSQNQVPTTGERVRDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKSSTPSRIES 285
Query: 229 NRSLNFKIPEEDMKALNQLSE-KNVKY 254
N + ++ EED A+ +++E ++V++
Sbjct: 286 NFIIP-ELSEEDFAAIQKVAEGRHVRF 311
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 108 bits (259), Expect = 2e-22
Identities = 68/189 (35%), Positives = 102/189 (53%), Gaps = 18/189 (9%)
Query: 72 DLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEG 131
D Y+DL LIH P G + E ++N +W LT +G V +GVSNF + HL+
Sbjct: 108 DKPYIDLMLIHAPWGGE---EGRKN------NWEALTIAQKEGWVKDIGVSNFGIHHLKA 158
Query: 132 LMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVV 191
L VPAVNQ+E HP+ Q + K+C++H I ++AY +N ++ V+V
Sbjct: 159 LPPP----VPAVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPL---VRANKKHYDNEVLV 211
Query: 192 STALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE- 249
A K AQVLL W+LQ+ +PK+V P I+ N L +FK+ +EDM ++ L +
Sbjct: 212 KVAKKYGKEVAQVLLRWSLQKGYIPLPKSVTPSRIESNADLYDFKLDQEDMAEIDGLDKG 271
Query: 250 KNVKYAWDP 258
+W+P
Sbjct: 272 SEGAISWNP 280
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 107 bits (258), Expect = 2e-22
Identities = 71/202 (35%), Positives = 107/202 (52%), Gaps = 18/202 (8%)
Query: 63 AYQKSLENLDLEYVDLYLIHFP-----GGAKLPA-EDKRNTKMREL----SWCKLTELYD 112
A + SL NL ++Y+DLYL+H+P G P D ++ +W + +L D
Sbjct: 93 ACETSLRNLGIDYLDLYLMHWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVD 152
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G VNA+GVSNF + L+ L P + Q+E HPY Q SL C + I + AY
Sbjct: 153 SGLVNAIGVSNFNEKQINRLL-CLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYS 211
Query: 173 SFGGTSC-----SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIK 227
S G + LL +P++VS A K TPAQVLL + Q + VIP++V +H+
Sbjct: 212 SLGSGHTPYEKPGSYPLLQNPIIVSVAEKYGRTPAQVLLRYQTQSGIIVIPRSVSKQHMH 271
Query: 228 EN--RSLNFKIPEEDMKALNQL 247
+N R +F++ +D+KA++ L
Sbjct: 272 DNFKRIWDFQLAIDDVKAIDGL 293
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
+F+L++G MP +GLGT+R ++V Q V A++ GYR F
Sbjct: 5 SFLLSSGRNMPMVGLGTWR-SPPEVVAQAVKDAIDIGYRHF 44
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 107 bits (258), Expect = 2e-22
Identities = 72/207 (34%), Positives = 107/207 (51%), Gaps = 23/207 (11%)
Query: 65 QKSLENLDLEYVDLYLIHFP------GGAKLPAEDKRNTKMRELS----WCKLTELYDDG 114
+ L+ L LEY+DLYLIH P G+ P + + E++ W L +LY +G
Sbjct: 96 ESQLKALQLEYIDLYLIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEG 155
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
K+ A+GVSNF+ L+ L ++ + PA QVE H Y+ Q L CK+ +T+ AY
Sbjct: 156 KLKALGVSNFSCNQLQALYDAAE-VKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPL 214
Query: 175 G----------GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
G G + LL +P+V A K T AQ+L+ Q ++ IPK+V P+
Sbjct: 215 GSPGRKAARPDGVWPEGDPLL-EPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPD 273
Query: 225 HIKENRS-LNFKIPEEDMKALNQLSEK 250
I EN S +FK+ +EDM LN + +
Sbjct: 274 RIVENISTFDFKLSDEDMHTLNSIETR 300
Score = 34.3 bits (75), Expect = 3.2
Identities = 14/37 (37%), Positives = 23/37 (62%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
LN G +P GLGT++++ + + AL+AGYR+
Sbjct: 8 LNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRL 44
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 107 bits (258), Expect = 2e-22
Identities = 66/187 (35%), Positives = 105/187 (56%), Gaps = 20/187 (10%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
Q+ + SLE L+ +Y+DLYLIH+P A +RE S + EL+D G V VGV
Sbjct: 117 QSCEASLERLETDYLDLYLIHWPNPA---------ISLRE-SLQAMAELHDRGLVRNVGV 166
Query: 122 SNFTVAHLEGLMESNH-GLVP-AVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
SNF+ L +NH VP AVNQ+E+HP++ + +L +C + ++A T
Sbjct: 167 SNFSAYQLSC---ANHISEVPIAVNQIEFHPWFQRPNLVDYCHESDTVIEAAAPLARTE- 222
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEE 239
+ +D VV A + +PAQV+L WAL +DV +P++ PEH++ N L++++
Sbjct: 223 ----VFDDEVVAELAESYDKSPAQVILRWALDRDVVALPRSSTPEHVRANADLDWELDAA 278
Query: 240 DMKALNQ 246
D + L++
Sbjct: 279 DRQRLDE 285
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 107 bits (258), Expect = 2e-22
Identities = 74/214 (34%), Positives = 113/214 (52%), Gaps = 21/214 (9%)
Query: 55 DHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
D+G RA +A+ +SL L L+YVDLYL+H+P +D T SW ++ D
Sbjct: 82 DYGYERALRAFDESLGRLGLDYVDLYLLHWP------TKDWNATIQ---SWKAAEKILGD 132
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G+ A+GV NF L+ L+ ++ +VPAVNQ+E HPY+ Q L + I +A+
Sbjct: 133 GRARAIGVCNFLEDQLDELIAASD-VVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSP 191
Query: 174 FGGTSCSNNS--------LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
GG + L DPV+ + A + AQV+L W Q DV IPK+V+PE
Sbjct: 192 IGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQNDVVAIPKSVNPER 251
Query: 226 IKENRSL-NFKIPEEDMKALNQLSEKNVKYAWDP 258
I +N + +F + + +M L++L + V+ DP
Sbjct: 252 IAKNIDVFDFALSDAEMAQLDEL-DTGVRIGPDP 284
>UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces
cerevisiae Probable oxidoreductase YJR096W; n=2;
Yarrowia lipolytica|Rep: Similar to sp|P47137
Saccharomyces cerevisiae Probable oxidoreductase YJR096W
- Yarrowia lipolytica (Candida lipolytica)
Length = 287
Score = 107 bits (257), Expect = 3e-22
Identities = 62/204 (30%), Positives = 107/204 (52%), Gaps = 14/204 (6%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVN 117
SR E+A K+ L+Y+D+ +IH P A E T+M+ W L+E DDGK+
Sbjct: 95 SRVEEALTKAKVG-GLDYIDMLIIHAPYTAPPHTE----TRMKV--WKALSEFVDDGKIR 147
Query: 118 AVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
+ VSN+ V HL+ +++ P +NQ+E P+ ++ +C +H I ++ Y +
Sbjct: 148 TLAVSNYGVKHLKEFWDADTKYKPVLNQIESSPWNVHQDIHDYCNEHDIVVEQY-----S 202
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKI 236
++P V S A K TPAQ+L+ W + + + IPK+ P+ K N + +FK+
Sbjct: 203 PLIRGKKFDEPGVQSLAKKYNKTPAQILIRWGIDKGMLPIPKSDQPQRQKSNADVFDFKL 262
Query: 237 PEEDMKALNQLSEKNVKYAWDPSI 260
+++ AL L + + WDP++
Sbjct: 263 TPDEVTALQDL-DSYLYLEWDPTV 285
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 107 bits (257), Expect = 3e-22
Identities = 70/195 (35%), Positives = 105/195 (53%), Gaps = 20/195 (10%)
Query: 61 EQAYQKSLENLDL-----EYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGK 115
E YQK LE+++ YVDL+LIH + + +EL W L L ++GK
Sbjct: 90 EATYQKLLESVEKIGGRDGYVDLFLIH--------SSSSGSAGRKEL-WQALERLLEEGK 140
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
++GVSNF V H+E + P VNQ+E HP+ Q + +CK++ I ++AY
Sbjct: 141 TRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAY---- 196
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
+ N NDP +V A K E T AQ+L+ +ALQ+ +PK+ PE I N ++ +F
Sbjct: 197 -SPLVRNYKANDPTLVDVAKKYERTTAQILIRYALQKGWVPLPKSDTPERIVANANVFDF 255
Query: 235 KIPEEDMKALNQLSE 249
+I EED+ LN L +
Sbjct: 256 EIGEEDLAVLNGLDQ 270
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 107 bits (257), Expect = 3e-22
Identities = 68/203 (33%), Positives = 112/203 (55%), Gaps = 20/203 (9%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLP------AEDKRNTKMREL------SWCKLTE 109
Q + SL L ++Y+DL+L+H+P G E + L +W K+ +
Sbjct: 93 QELENSLNELGIDYIDLWLLHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMED 152
Query: 110 LY---DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
++ GKV A+GVSNF++ +LE L +++ + PAVNQ+E HPY + L K+CK I
Sbjct: 153 VFLNSHKGKVKAIGVSNFSIKNLEILAKTSK-VTPAVNQIEAHPYLPEHELVKYCKHKSI 211
Query: 167 TLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
+ AY G N S+ D + A K +VT A V L WA+Q+ +V PK+ + + +
Sbjct: 212 HVTAYSPLGQ---YNASIHEDKDLNEIAKKHDVTAATVALSWAVQRGTSVAPKSTNEKRM 268
Query: 227 KENRSLNFKIPEEDMKALNQLSE 249
K+N +L K+ +E+MK ++ +S+
Sbjct: 269 KQNITL-IKLTDEEMKQVDVISQ 290
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 107 bits (257), Expect = 3e-22
Identities = 61/194 (31%), Positives = 107/194 (55%), Gaps = 17/194 (8%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A + SL+ L +Y+DLYL+H+P A T +RE T L+D GK+ VGV
Sbjct: 71 EACEASLDRLGTDYLDLYLVHWPNPA---------TSIRETMNAMAT-LHDQGKIRNVGV 120
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
SNF+ L G + + AVNQ+E+HP+ TQ + +FC+ ++A G T
Sbjct: 121 SNFSAYQL-GAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLGRTK--- 176
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+ D ++ + K + +PAQ++L WA++ +V V+PK+ PEH+++N L ++++ D
Sbjct: 177 --VFADDIIQDLSEKYDRSPAQIVLKWAVENNVVVLPKSSSPEHVRQNFDLFDWELDATD 234
Query: 241 MKALNQLSEKNVKY 254
+ ++ + + Y
Sbjct: 235 RERIDAIEREQAVY 248
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 107 bits (256), Expect = 4e-22
Identities = 66/202 (32%), Positives = 110/202 (54%), Gaps = 15/202 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+ +A+++SL+ L L+YVDLYLIH+P P+E N W L EL + G+ +
Sbjct: 89 KPREAFERSLDLLSLDYVDLYLIHWPCP---PSELYINV------WEVLLELKESGRAKS 139
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
VGVSNF H++ + E+ L P+VNQ+E HP+ Q L C+ I ++++ F S
Sbjct: 140 VGVSNFLSEHIDKIKEAGFPL-PSVNQIELHPWLQQRELVLSCRNDGIQIESWGPFARFS 198
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
++ P + A + TPAQV+L W +Q+ V PK VH E +++N + +F +
Sbjct: 199 KDLDAF---PELTRPAKQYGKTPAQVILRWHIQKGYVVFPKTVHAERLRQNIDIFDFDLT 255
Query: 238 EEDMKALNQLSEKNVKYAWDPS 259
+++ ++ L + + DPS
Sbjct: 256 PDEISGIDSL-DAGFRTGPDPS 276
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 107 bits (256), Expect = 4e-22
Identities = 65/206 (31%), Positives = 112/206 (54%), Gaps = 12/206 (5%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAK------LPAEDKRNTKMR-ELSWCK 106
SDH Q +L+ + L+Y+D YL+H+P K +P ED+ + E +W
Sbjct: 85 SDHHDPISALIQ-TLKTMGLDYLDNYLVHWPIKLKPGVSEPIPKEDEFEKDLGIEETWQG 143
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
+ + G ++GVSNF+ + L++ + P+VNQVE HP + Q L K C++++I
Sbjct: 144 MERCLEMGLCRSIGVSNFSSKKIFDLLDFA-SVSPSVNQVEMHPLWRQRKLRKVCEENNI 202
Query: 167 TLQAYCSFGGT-SC-SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
+ Y GG +C + +++ P++ S ALK TPAQV L W + + +VI K+ +
Sbjct: 203 HVSGYSPLGGPGNCWGSTAVIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFNGA 262
Query: 225 HIKEN-RSLNFKIPEEDMKALNQLSE 249
+ EN R+L K+ ++D+ ++ L E
Sbjct: 263 RMIENKRALEIKLDDQDLSLIDHLEE 288
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 107 bits (256), Expect = 4e-22
Identities = 67/180 (37%), Positives = 97/180 (53%), Gaps = 11/180 (6%)
Query: 81 IHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV 140
I P G P D ++ +W + L D GK+ +GVSNF + LE L+ S +
Sbjct: 162 IRHPNGK--PIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR-IP 218
Query: 141 PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVT 200
PAVNQ+E HPY Q L +FCK + I L A+ GG + +P A K E +
Sbjct: 219 PAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPVA----AVNPNADRPASKHERS 274
Query: 201 PAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEEDMKALNQLSEK--NVKYAWDP 258
PAQ++L W +QQ ++VIPK V + EN L ++P++DM+ + LS+K V+Y DP
Sbjct: 275 PAQIILSWIVQQGISVIPKTVRQSRMVENLDLK-QLPDKDMETIYDLSKKKGEVRYL-DP 332
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 106 bits (255), Expect = 5e-22
Identities = 65/195 (33%), Positives = 105/195 (53%), Gaps = 14/195 (7%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
+D A A +SLE L L+YVDLYLIH+P P +D+ +W +L EL +
Sbjct: 79 NDRHLDARAALTESLEKLQLDYVDLYLIHWPA----PPQDQYVG-----AWQQLIELQKE 129
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G + ++GVSNF H++ L+ G+ P +NQ+E HP Q L+ + H+I + S
Sbjct: 130 GLIRSIGVSNFQPEHIQRLINET-GVHPVINQIELHPLLQQRQLHAWNATHNIVTE---S 185
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
+ + ++ ++ +V K TPAQV++ W + + VIPK+ IKEN +
Sbjct: 186 WSPLAQGGENVFDNQLVQHLTQKYGKTPAQVVIRWHIDNGMIVIPKSTTLSRIKENFDVF 245
Query: 233 NFKIPEEDMKALNQL 247
+FK+ +ED+ A+ L
Sbjct: 246 DFKLEKEDLTAMTTL 260
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 106 bits (255), Expect = 5e-22
Identities = 64/209 (30%), Positives = 106/209 (50%), Gaps = 17/209 (8%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKV 116
G Q++ +SLE L L+YVDLYL+H P AK N + + +W ++ ++ D G
Sbjct: 112 GDTVTQSFNRSLEKLGLDYVDLYLLHSPFFAK-------NPEQLQAAWREMEKIKDSGMA 164
Query: 117 NAVGVSNFTVAHLEGLMESNHGL--VPAVNQVEWHPYYTQ----SSLYKFCKQHHITLQA 170
++GVSNF ++HL+ L + GL P VNQ+E+HPY L FC++ HI + A
Sbjct: 165 KSIGVSNFLISHLQTLFDIPGGLQYPPVVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAA 224
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKE-- 228
Y + + + DP+ A K V+ A++ W L Q + + + + E +K
Sbjct: 225 YSPLTAITKARPGPV-DPIYTQLAKKYGVSEAEIAFRWCLDQGIVTLTTSSNEERLKGYL 283
Query: 229 NRSLNFKI-PEEDMKALNQLSEKNVKYAW 256
+ +FK+ P+E + EK+ + W
Sbjct: 284 KKLPSFKLTPKEVEDIASAGKEKHYRVWW 312
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 106 bits (254), Expect = 7e-22
Identities = 70/195 (35%), Positives = 105/195 (53%), Gaps = 20/195 (10%)
Query: 61 EQAYQKSLENLDL-----EYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGK 115
E Y+K LE+++ YVDL+LIH + + +EL W L +L ++GK
Sbjct: 90 EATYKKLLESVEKIGGENGYVDLFLIH--------SSSSGSAGRKEL-WQALEKLLEEGK 140
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
++GVSNF V H+E + P VNQ+E HP+ Q + +CK++ I ++AY
Sbjct: 141 TKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAY---- 196
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNF 234
+ N NDP +V A K T AQVL+ +ALQ+ +PK+ PE I+ N + +F
Sbjct: 197 -SPLVRNYKANDPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPKSDTPERIEANTKVFDF 255
Query: 235 KIPEEDMKALNQLSE 249
+I EEDM LN L +
Sbjct: 256 EISEEDMAVLNALDQ 270
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 105 bits (253), Expect = 9e-22
Identities = 60/193 (31%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAED--KRNTKMRELSWCKLTELYDDGKVNA 118
E+ SL L +YVDL LIH+P +D + N R++ W L + + G+V +
Sbjct: 99 EKQLANSLATLQTDYVDLLLIHYPRDRDTGNDDDYEINKSRRKIVWQTLEKAKESGRVRS 158
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSN+ V HL + E + P +NQ E+ PY T+ +L KFC ++I +Q+Y S
Sbjct: 159 IGVSNYEVYHLVEMFEYAK-IRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSL---C 214
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN--RSLNFKI 236
+ +L + +V K TP +L +A + ++IPK+ P I +N ++ K+
Sbjct: 215 WGDKEILQEKPLVDLCQKYNQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKL 274
Query: 237 PEEDMKALNQLSE 249
E+++K+L L +
Sbjct: 275 TEDELKSLRSLDK 287
Score = 34.7 bits (76), Expect = 2.4
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
++ F ++G MP IGLG RI + ++ AL++GYR F
Sbjct: 7 VVGGAFKFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQF 51
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 105 bits (252), Expect = 1e-21
Identities = 66/218 (30%), Positives = 116/218 (53%), Gaps = 17/218 (7%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAK----LP--AEDKRNTKMREL 102
+++ + H A +++L +L L+ +DLYLIH+P + P +D + + L
Sbjct: 77 KLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVDFPESPDDFVSPEAVPL 136
Query: 103 --SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKF 160
+W + L DG V +GVSNF+V +L+ ++++ + P +NQVE HPY Q L F
Sbjct: 137 TETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE-VRPEMNQVEMHPYLPQPELVSF 195
Query: 161 CKQHHITLQAYCSFGG-------TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQD 213
+ H+I + AY G + +L+ +P + A + V+PAQVLL W + +
Sbjct: 196 AEAHNIPITAYSPLGSGDRPDAMKADDEPTLMANPTINDIADRHGVSPAQVLLQWGVARG 255
Query: 214 VAVIPKAVHPEHIKEN-RSLNFKIPEEDMKALNQLSEK 250
AVIPK+ P HIK+N + + + ++++ ++ L K
Sbjct: 256 TAVIPKSTTPAHIKDNLAAADLDLSADELETIDSLDSK 293
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 16 NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
NG MP IGLGT++ + V + V ALEAGYR
Sbjct: 8 NGDEMPMIGLGTWKSPPGE-VYEAVTTALEAGYR 40
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 105 bits (252), Expect = 1e-21
Identities = 64/194 (32%), Positives = 103/194 (53%), Gaps = 15/194 (7%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A+ ++L +L L+Y+DLYLIH+P ED + +W L LY KV A+GVS
Sbjct: 87 AFDQTLSDLQLDYLDLYLIHWPN------EDDFELTLD--TWRVLETLYQQKKVRAIGVS 138
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF+ L+ + E + P +NQ+E HPY Q+ L +F + I + Y G +
Sbjct: 139 NFSEDQLKQVFEMAT-VKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSPIG----HGH 193
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLN-FKIPEEDM 241
+L DPV+ A K +PAQ++L W + V PK+ P +KEN ++ F + +++
Sbjct: 194 LILEDPVITKLAEKYGKSPAQIVLRWQIDTGFVVFPKSSKPARVKENFEISGFSLTADEI 253
Query: 242 KALNQL-SEKNVKY 254
+N L +K++ Y
Sbjct: 254 AEINGLDQDKHLNY 267
Score = 37.1 bits (82), Expect = 0.45
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLEN 70
T L+NG+ +P +G GTY I D V + AL+AGYR H E A ++++
Sbjct: 3 TTQLSNGVTIPMLGFGTYLIDSKD-VPAAIKTALDAGYR-HLDCAHIYGNEPAVGEAIKA 60
Query: 71 LDLEYVDLYL 80
++ DL++
Sbjct: 61 SGIDRSDLFI 70
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 105 bits (252), Expect = 1e-21
Identities = 64/196 (32%), Positives = 106/196 (54%), Gaps = 21/196 (10%)
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTV 126
S++ L Y+DL+L+H P G ++ SW L + ++GK+ A+GVSNF
Sbjct: 96 SVKACGLGYIDLFLLHSPYGDRIE------------SWKALEKGVEEGKLRAIGVSNFGP 143
Query: 127 AHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF-GGTSCSNNSLL 185
H++ L++S+ ++P VNQ+E HP+ +Q + +C+ I L AY G N LL
Sbjct: 144 HHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPLVHGEKFGNKQLL 203
Query: 186 NDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKAL 244
+ A K + AQ+++ + LQ+ V+PK+ P IKEN + +F+I +EDM+ L
Sbjct: 204 ------AIASKYNKSEAQIMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKL 257
Query: 245 NQLSEKNVKYAWDPSI 260
L E + W+P +
Sbjct: 258 YNLDE-DYHSDWNPCV 272
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 105 bits (251), Expect = 2e-21
Identities = 66/202 (32%), Positives = 105/202 (51%), Gaps = 12/202 (5%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFP-------GGAKLPAEDKRNT-KMRELS-WCK 106
HG E ++SL +L ++YVDLYLIH+P G K N K + W K
Sbjct: 86 HGC-PEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKK 144
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
+ L D G ++G+SNF A+ E ++ + + PA Q+E HPY Q L +F K I
Sbjct: 145 MEALVDLGLAKSIGISNFGKANTEKILGTCR-ICPAAIQIELHPYLNQKELVEFMKSKGI 203
Query: 167 TLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
+ +Y S G S+ + +D + + A K P+Q++L + Q + VIPK+ EH+
Sbjct: 204 QVISYSSLGSAPGSSAKVRDDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHL 263
Query: 227 KENRSLNFKIPEEDMKALNQLS 248
+EN L ++ ED+ A++ L+
Sbjct: 264 RENIDLK-ELSREDISAIDALN 284
Score = 33.9 bits (74), Expect = 4.2
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+I T LNNG +P++GLGT+ + ++ + AL GYR
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYR 43
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 104 bits (250), Expect = 2e-21
Identities = 86/295 (29%), Positives = 137/295 (46%), Gaps = 59/295 (20%)
Query: 8 IPTTFVLNNGIMMPSIGLGT--------------------------YRIRQSDIVMQVVD 41
IPT LNNG+ MP+IGLGT Y R D+V + +
Sbjct: 6 IPTV-KLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIR 64
Query: 42 YALEAGY----------RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGG----- 86
+E G +++ H A+ KSLE+L L+YVDL+LIH P G
Sbjct: 65 AKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNG 124
Query: 87 ----AKLPAEDKRNTKMRE----LSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHG 138
+ P +D N + +W + +L + G+V+++GVSNF LE ++ +N
Sbjct: 125 WDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERIL-ANCR 183
Query: 139 LVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNS-------LLNDPVVV 191
+ P NQVE Q L +FC + I + A+ FG + +L++P +V
Sbjct: 184 VKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPHLFEKNPKDKPKPVLDEPEIV 243
Query: 192 STALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALN 245
K + + AQV+L + LQ V IPK+ +H+K+N + +F++ +DM L+
Sbjct: 244 EIGKKFDKSSAQVVLRYLLQNGVVPIPKSTSAQHLKQNLEIFDFELSSDDMAILD 298
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 104 bits (250), Expect = 2e-21
Identities = 65/191 (34%), Positives = 100/191 (52%), Gaps = 20/191 (10%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFP----------GGAKLPAEDKRNTKMREL--- 102
H ++A +SL+ L L+YV LYL+H+P G AE +K +L
Sbjct: 85 HQRNPQEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDGNLFQFAEKPDGSKDVDLEWN 144
Query: 103 ---SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMES-NHGLVPAVNQVEWHPYYTQSSLY 158
+W + +L + GK A+GVSNF+V +L+ L+ + + PAVNQVE+HP Q L
Sbjct: 145 FIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELI 204
Query: 159 KFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIP 218
++C + I ++AY GG N +L+DP V A V V++ WA+Q+ + +P
Sbjct: 205 QYCSEKGIVIEAYSPLGG---ENAPILSDPTVQEIAKANGVEAGHVVISWAVQKGLVTLP 261
Query: 219 KAVHPEHIKEN 229
K+V P I N
Sbjct: 262 KSVTPSRIVGN 272
Score = 37.1 bits (82), Expect = 0.45
Identities = 17/40 (42%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+T LN G +P +GLGT+R ++++ V++ AL+AGYR
Sbjct: 9 STLKLNTGQTIPQVGLGTWRSKENEGYKAVIE-ALKAGYR 47
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 104 bits (249), Expect = 3e-21
Identities = 62/188 (32%), Positives = 111/188 (59%), Gaps = 15/188 (7%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
++AY +SL L L+++D+++ H+P +PA K +W L +L ++G+V A+G
Sbjct: 97 QRAYDESLRKLGLDHLDMFMCHWP----VPALGKYVD-----AWKGLVKLLEEGRVKAIG 147
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
VSNF AHL+ ++++ G+VP VNQ++ P ++ + I +A+ G +S
Sbjct: 148 VSNFKPAHLKDIIDAT-GVVPDVNQIQLSPDLARTEPRAVHRLLGIVTEAWSPIGRSS-- 204
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEE 239
L +P+++ A +L+ +PAQVLL W +QQD+ IP+A P +KEN S+ +F +
Sbjct: 205 --GLRANPLIIEIAQRLDKSPAQVLLRWHVQQDIVPIPQASDPLWLKENLSVFDFSLTAG 262
Query: 240 DMKALNQL 247
+M ++ +L
Sbjct: 263 EMASIRKL 270
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 104 bits (249), Expect = 3e-21
Identities = 71/210 (33%), Positives = 111/210 (52%), Gaps = 20/210 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMRELSWC----KLTELYDD 113
A +KSL+ L L+YVDLY++H+P G P ++ + + + +C +L E D
Sbjct: 98 ALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDA 157
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGL--VPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
G V ++GVSNF LE ++ + GL P NQVE H Y Q L +C+ I L AY
Sbjct: 158 GLVKSIGVSNFNHRQLERIL-NKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAY 216
Query: 172 CSFGGTS----CSNNS--LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
+ G NS LLNDPV+ A K + +PA + L + +Q+ + + ++
Sbjct: 217 GALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENE 276
Query: 226 IKEN-RSLNFKIPEEDMKALNQLSEKNVKY 254
++EN + F++ EDMK L+ L+ KN +Y
Sbjct: 277 MRENLQVFGFQLSPEDMKTLDGLN-KNFRY 305
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 103 bits (248), Expect = 3e-21
Identities = 67/175 (38%), Positives = 96/175 (54%), Gaps = 25/175 (14%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A++K+L++L L Y+D+YLIH+P G K + EL D+G V A+G+
Sbjct: 117 KAFEKTLKDLKLSYLDVYLIHWPQGFKA-----------------MEELVDEGLVKALGI 159
Query: 122 SNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG--- 176
SNF +E L+ + GL P NQVE HPY TQ L ++C IT+ AY G
Sbjct: 160 SNFNHFQIEKLL-NKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSPLGSPDR 218
Query: 177 --TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN 229
+ SLL +P + A K + T AQVL+ + +Q++V VIPK+V P I EN
Sbjct: 219 PWAKPEDPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSVTPARIVEN 273
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 103 bits (248), Expect = 3e-21
Identities = 62/209 (29%), Positives = 113/209 (54%), Gaps = 20/209 (9%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGG-------AKLPAEDKRNTKMREL----SWCKLTEL 110
+ + +SL +L L+Y+DLY++H+P G P + + ++ +W + +L
Sbjct: 91 ECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDL 150
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLV-PAVNQVEWHPYYTQSSLYKFCKQHHITLQ 169
GK ++G+SNF L+ +++ H V P+V QVE HP+ Q L FC++ + +
Sbjct: 151 VKTGKCKSLGLSNFNSKQLDDVLQ--HSTVPPSVLQVESHPFLPQVELLNFCRERSVVVS 208
Query: 170 AYCSFG-GTSC----SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
AY G G S+ +DP ++ A +L + AQV + + +Q+ + VIPK+ P
Sbjct: 209 AYSPLGCGDRAWKLSGEPSIFDDPGLLKIAQRLRKSIAQVAIRFQVQRGIPVIPKSATPS 268
Query: 225 HIKENRSL-NFKIPEEDMKALNQLSEKNV 252
HI+EN ++ +F++ E+DM L+ L + +
Sbjct: 269 HIQENINVFDFELSEDDMALLSSLPRRRI 297
Score = 36.7 bits (81), Expect = 0.60
Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 4/70 (5%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAE--QAYQKSLEN 70
L +G MP +GLGT++++ +D V + A++AGYR F +G+ E A +++++
Sbjct: 7 LPSGHAMPLVGLGTWKLK-ADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQR 65
Query: 71 LDLEYVDLYL 80
L L+ D+++
Sbjct: 66 LGLKREDVFI 75
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 103 bits (248), Expect = 3e-21
Identities = 68/209 (32%), Positives = 106/209 (50%), Gaps = 19/209 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAK-----LPAEDKRNTKMRELSWCK----LTELYDD 113
A +K+L++L+L+Y+DLYL+H+P K P +D+ + E + + E
Sbjct: 91 ALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQ 150
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G + VGVSNF+ LE L + P +NQVE HPY Q+ LY +C + I L Y
Sbjct: 151 GLIKHVGVSNFSKEKLESLKGKVEEM-PEMNQVELHPYLPQNDLYSYCSKEGILLTGYSP 209
Query: 174 FGGTSCSNN-------SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
G S SL D + A + ++ Q L+ WA Q+ AVIPK+ + I
Sbjct: 210 LGSGDRSEGMKADDEPSLFEDDTIKKVAERNNISKGQTLIAWAKQRGTAVIPKSTNEGRI 269
Query: 227 KEN-RSLNFKIPEEDMKALNQLSEKNVKY 254
KEN S N ++ +ED++ + + KN ++
Sbjct: 270 KENLESDNIELSKEDLEDIANIG-KNYRF 297
Score = 39.5 bits (88), Expect = 0.085
Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF---APSDHGSRAEQAYQK 66
TT +G +PSIGLGT++ D V + V ALE GY+ A D+ +A+++
Sbjct: 2 TTLKFRDGDSIPSIGLGTWKSDPED-VKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKE 60
Query: 67 SLENLDLEYVDLYL 80
S E+ +++ D+++
Sbjct: 61 SFESGNVKREDIFV 74
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 103 bits (248), Expect = 3e-21
Identities = 72/223 (32%), Positives = 110/223 (49%), Gaps = 25/223 (11%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFP--------GGAKLPAEDKRN---TKMREL 102
S+ E +KSLE+L L+YVDLYL+H P G KL E T
Sbjct: 85 SNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEVDVTTNHAA 144
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
W + L + G ++GVSNF+ + L++ N + PA NQ+E H Y Q L FCK
Sbjct: 145 IWVAMEALVEKGLTKSIGVSNFSKDQVARLLK-NCKIRPANNQIEHHVYLQQRDLVDFCK 203
Query: 163 QHHITLQAYCSFGGTSCSNNS-----------LLNDPVVVSTALKLEVTPAQVLLVWALQ 211
+IT+ AY G + + L++ P V A TPAQVLL W +
Sbjct: 204 SENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIID 263
Query: 212 QDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSEKNVK 253
V+ IPK+ +P +K+N + +F++ E++ L+ L ++N++
Sbjct: 264 TGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSL-DQNIR 305
Score = 37.9 bits (84), Expect = 0.26
Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 7 IIPTTFV-LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
++ T F+ NNG MP IG+GT++ +I +D ALEAGYR
Sbjct: 1 MVNTKFLTFNNGEKMPVIGIGTWQASDEEI-ETAIDAALEAGYR 43
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 103 bits (247), Expect = 5e-21
Identities = 70/209 (33%), Positives = 105/209 (50%), Gaps = 18/209 (8%)
Query: 52 APSDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
A +D G ++ A + SLE L L+YVDLYLIH+P G D SW L +
Sbjct: 85 AVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAGDHGKYID---------SWGGLMKA 135
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
DG ++GV NF HL +++ + PA+NQ+E HP Q+ L + + I +A
Sbjct: 136 KQDGVARSIGVCNFNAEHLSNIIDLSF-FTPAINQIELHPLLNQAELREVNAGYGIVTEA 194
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
Y G LL+ V A TPAQVLL W++Q VI ++ +P+ I N
Sbjct: 195 YGPLG-----VGRLLDHAAVTGVAQAHGKTPAQVLLRWSIQLGNVVIARSANPDRITSNL 249
Query: 231 SL-NFKIPEEDMKALNQLSEKNVKYAWDP 258
+ +F++ +++M LN L E ++ DP
Sbjct: 250 EVFDFELTDDEMATLNGLDE-GTRFRPDP 277
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 103 bits (247), Expect = 5e-21
Identities = 82/253 (32%), Positives = 126/253 (49%), Gaps = 34/253 (13%)
Query: 9 PT-TFVLNNGIMMPSIGLGTYRIRQ-SDIVMQVVDYALEAGYRMF--------------A 52
PT +F L NG +P+IGLGT++ ++ V +V A++AGYR A
Sbjct: 4 PTASFRLVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDA 63
Query: 53 PSDHGSRAEQAYQKSLENLDLE-YVDLYL----IHFPGGAKLPAED----KRNTKMRELS 103
+ G ++ Q E D+E +DL L + + A LP + +R+ K E +
Sbjct: 64 IKESGISRDELAQPWHEPKDVERALDLSLEALGLEYVPHAYLPGPNNVDYERSRKYTE-T 122
Query: 104 WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQ 163
W + +L D GK A+G+SNF + + ++E + PAVNQVE HPY+ Q L FC++
Sbjct: 123 WQAMEKLVDSGKAKAIGLSNFNILKTKRILEIAR-IRPAVNQVEAHPYFPQHELLAFCEK 181
Query: 164 HHITLQAYCSFGG-------TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAV 216
HI L A+ GG L D + A + +TPAQV+L WA+Q+ ++
Sbjct: 182 EHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMTPAQVILSWAVQRGTSI 241
Query: 217 IPKAVHPEHIKEN 229
IPK + + EN
Sbjct: 242 IPKTSNESRLSEN 254
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 103 bits (247), Expect = 5e-21
Identities = 58/159 (36%), Positives = 94/159 (59%), Gaps = 6/159 (3%)
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGL--VPAVNQVEWHPYYTQSSLYKF 160
+W + +L G V +GVSNF LE L+ + GL P NQ+E HPY TQ +L F
Sbjct: 151 TWEAMEDLVITGLVKNIGVSNFNHEQLERLL-NKPGLRFKPLTNQIECHPYLTQKNLISF 209
Query: 161 CKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
C+ +++ AY GG SC L+++PV+ A + +PAQ+L+ + +Q++V VIP +
Sbjct: 210 CQSRDVSVTAYRPLGG-SCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGS 268
Query: 221 VHPEHIKEN-RSLNFKIPEEDMKALNQLSEKNVKYAWDP 258
+ P HIKEN + +F++ + DM + L+ +N++ A P
Sbjct: 269 ITPSHIKENIQVFDFELTQHDMDNILSLN-RNLRLAMFP 306
Score = 41.1 bits (92), Expect = 0.028
Identities = 23/48 (47%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWC 105
S E A +KSL+ L L Y+DLYLIH+P G K P + ELS+C
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPMGFK-PPHPEWIMSCSELSFC 124
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 103 bits (246), Expect = 6e-21
Identities = 53/150 (35%), Positives = 88/150 (58%), Gaps = 9/150 (6%)
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLV--PAVNQVEWHPYYTQSSLYKF 160
+W + EL DDG A+G+SNF +E ++ + GL PA NQ+E HP+ Q L F
Sbjct: 165 TWEAMEELVDDGLAKAIGISNFNKDQIEAVL-NKPGLKHKPATNQIECHPHLNQEKLIHF 223
Query: 161 CKQHHITLQAYCSFGGT-----SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVA 215
C+ I++ A+ G S S L+DP + + A K ++TPAQVL+ + +Q+++
Sbjct: 224 CRSRGISVTAFACLGSADRSWASADEPSFLDDPQINAIARKNQMTPAQVLIKFQIQRNIT 283
Query: 216 VIPKAVHPEHIKEN-RSLNFKIPEEDMKAL 244
+ K+V P IKEN ++ ++++ ++DMK L
Sbjct: 284 AVVKSVSPHRIKENIKAFDYELSDDDMKTL 313
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/25 (64%), Positives = 22/25 (88%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGA 87
A +K+L +L+L+YVDLYL+HFP GA
Sbjct: 92 ACEKTLSSLNLDYVDLYLMHFPMGA 116
Score = 33.9 bits (74), Expect = 4.2
Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+IP+ LN G +MP +GLGT++ + + + V A+ AGYR
Sbjct: 1 MIPSV-TLNTGALMPVLGLGTWKSGKG-VTTEAVKVAIGAGYR 41
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 101 bits (243), Expect = 1e-20
Identities = 60/197 (30%), Positives = 103/197 (52%), Gaps = 7/197 (3%)
Query: 54 SDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
S+ ++ E ++SL+NL Y+DLYL+H+ + + + ++ W + EL
Sbjct: 85 SNKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTDQFELTHKPVFQV-WAEFEELVQK 143
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G + +G+SNF V L L S + P VNQ+E + Y Q L +FCK+ ++ + AYC
Sbjct: 144 GLIRNIGISNFNVQMLLDLY-SYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCP 202
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSL 232
C N ND ++ + K + + Q++L + L V+VIPK + E ++EN S
Sbjct: 203 L--ARCQNTD--NDALLTELSTKYKKSVCQIMLQFLLSLGVSVIPKTQNLERLRENIEST 258
Query: 233 NFKIPEEDMKALNQLSE 249
+F + E D+ L L++
Sbjct: 259 DFSLDEADIAKLKGLNK 275
Score = 32.7 bits (71), Expect = 9.7
Identities = 15/39 (38%), Positives = 23/39 (58%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T L NG +P GLGTY++ + ++ + AL+ GYR
Sbjct: 7 TTELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYR 45
>UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus
tropicalis|Rep: LOC548351 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 248
Score = 101 bits (243), Expect = 1e-20
Identities = 56/159 (35%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 102 LSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
L CK + G ++GVSNF + HL+ L E + +VP +NQVE+HP+ L +C
Sbjct: 94 LDSCKRLGVDYLGICRSIGVSNFLIHHLDQLKEDCN-MVPHLNQVEYHPFQRPQELVDYC 152
Query: 162 KQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAV 221
++++I + YC + LN PV+ A TPAQV + W++Q + IPK+
Sbjct: 153 RRNNIVFEGYCPL-----AKGQALNHPVIQKIAKNYGKTPAQVCIRWSIQNGIVTIPKST 207
Query: 222 HPEHIKEN-RSLNFKIPEEDMKALNQLSEKNVKYAWDPS 259
E I+EN F + +ED+ ALN L + +WDPS
Sbjct: 208 KEERIQENCEVFGFVLADEDVLALNALHDGR-HISWDPS 245
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 101 bits (243), Expect = 1e-20
Identities = 68/211 (32%), Positives = 110/211 (52%), Gaps = 18/211 (8%)
Query: 56 HG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGA---KLPAEDKRNTKMRELS-----WCK 106
HG + E A +SL+NL ++Y++LYLIH+P G K AE + E S W
Sbjct: 101 HGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEKTFAESVDDLLTPEESPISETWEA 160
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
+ D G +GVSNFTV L+ L+ S+ P VNQVE HP Q +L ++C I
Sbjct: 161 MESTRDKGLTKHIGVSNFTVKKLQQLV-SHCKQKPEVNQVEHHPLLQQPTLIEYCASEEI 219
Query: 167 TLQAYCSFGGTSCSNN-------SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPK 219
+ AY G + ++L+ PV+ + A +PAQV+L W +Q+ ++ IPK
Sbjct: 220 LITAYSPLGSMDRPQSLKVKDAPAVLDHPVIRAIAETRGCSPAQVVLAWDVQRGISAIPK 279
Query: 220 AVHPEHIKEN-RSLNFKIPEEDMKALNQLSE 249
+V P + EN ++ + ++ +++ + L +
Sbjct: 280 SVKPSRLLENLQAADIQLSNTELQKIEALDQ 310
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 101 bits (243), Expect = 1e-20
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
+W L +L D GKV ++GVSNFT+ +E L+++ + PAVNQ+E HPY Q +L+K+ K
Sbjct: 161 TWAALEKLVDAGKVRSIGVSNFTIEKIEELLKTAR-IPPAVNQIEAHPYLQQPALHKYLK 219
Query: 163 QH--HITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
+ +I AY G + +++DP V A KL PA +L+ WA+Q+ +V+PK+
Sbjct: 220 EKVTNILSVAYSPLGNNIYNAPRVVDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLPKS 279
Query: 221 VHPEHIKEN 229
V P I+ N
Sbjct: 280 VTPSRIESN 288
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 101 bits (242), Expect = 2e-20
Identities = 68/215 (31%), Positives = 109/215 (50%), Gaps = 24/215 (11%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMREL----------SWC 105
E+A + L L+L+Y+DLYL+H+P G P + + ++ +W
Sbjct: 93 EKALDECLAELELDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWK 152
Query: 106 KLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHH 165
+T+L K VGVSN + HLE ++ + G+VPAVNQ+E HP + L ++C++
Sbjct: 153 AMTQL-PKSKARTVGVSNHMIPHLEAIINAT-GVVPAVNQIERHPVLQSNELIEYCQKKG 210
Query: 166 ITLQAYCSFGGTSCSNNSLLNDPVV------VSTALKLEVTPAQVLLVWALQQDVAVIPK 219
I + AY +FG L+ P V S L VTPAQV+L W+ +VIPK
Sbjct: 211 IHVTAYSAFGNNGFGVPLLVTRPEVKEVAESASKRLGTTVTPAQVILAWSQVGGHSVIPK 270
Query: 220 AVHPEHIKENRSLNFKIPEEDMKALNQLSEKNVKY 254
+V P I EN ++ E++ +++L + +Y
Sbjct: 271 SVTPSRIHENFK-EVELTPEEIAKVSELGKDRRRY 304
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 100 bits (240), Expect = 3e-20
Identities = 67/191 (35%), Positives = 102/191 (53%), Gaps = 17/191 (8%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A A Q +L L L+Y DL LIH P R+ EL W L +DG +
Sbjct: 68 AYNATQANLRELGLDYADLILIHRP---------PRHGAGEEL-WRALIRAREDGLTRDI 117
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GVSN+++ +E L+++ G +P VNQVEW P+ L + + I +QAY +
Sbjct: 118 GVSNYSIELIEELVDAT-GEIPVVNQVEWSPFGHDLELKHYADFNGIVIQAY-----SPL 171
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
+ + L+D + TA K TPAQVL+ W L++ IPKA H+KEN S+ +F + +
Sbjct: 172 TRATRLDDAALCETAEKYGKTPAQVLIRWNLERGTVPIPKANLHSHMKENISVFDFTLEK 231
Query: 239 EDMKALNQLSE 249
D+++L+ L+E
Sbjct: 232 SDLESLDSLNE 242
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 100 bits (239), Expect = 4e-20
Identities = 60/193 (31%), Positives = 104/193 (53%), Gaps = 17/193 (8%)
Query: 66 KSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMREL-----SWCKLTELYDDGK 115
+SL+NL L+Y+D+YL+H+P G + P + K + +W + ++++
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
++G+SNF ++ L++S + P +NQ+E HPY QS L KFC IT+ +Y G
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAK-IAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389
Query: 176 GTS-----CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
+ + ++NDP + K +PAQ+LL + +Q VIPK+ + + EN
Sbjct: 390 SPARPWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVENM 449
Query: 231 SL-NFKIPEEDMK 242
S+ +F + E+DMK
Sbjct: 450 SIFDFTLSEDDMK 462
Score = 75.4 bits (177), Expect = 1e-12
Identities = 54/190 (28%), Positives = 94/190 (49%), Gaps = 16/190 (8%)
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTV 126
+L+ L + Y+DLYLI P K + + E +W + LY + A+G+SNF
Sbjct: 98 TLKKLQVAYLDLYLIERPPACK-------DHNLIE-TWEAMEGLYSEKLTRAIGLSNFNS 149
Query: 127 AHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG-TSCSNNSL- 184
+E ++E N + P VNQ++ HPY Q+ L K+C + I + +Y G + SL
Sbjct: 150 KQIERILE-NCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLGARNNIQPESLD 208
Query: 185 -LNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEEDMKA 243
L+D + A + TP +++L + +Q VI + I+ +F + EDM
Sbjct: 209 VLSDCRIKEIARRYNKTPTEIVLKYNVQLGNIVISDML----IESANFFDFYLAPEDMSY 264
Query: 244 LNQLSEKNVK 253
++ S +++K
Sbjct: 265 ISTFSSESLK 274
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 100 bits (239), Expect = 4e-20
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 17/188 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
++ +SL+ L L+Y+DL LIH P A W + EL GK+ A+GVS
Sbjct: 88 SFDRSLKRLGLDYIDLLLIHQPYNDVYGA------------WMAMEELQAQGKIKAIGVS 135
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF V + L N + P VNQ+E +P+ QS + ++ + ++A+ F N
Sbjct: 136 NFGVDRVVDLAAFND-ITPQVNQIEINPFQQQSKNIEALRKEGVAVEAWAPFAE---GKN 191
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
+ +P++ A K + AQV+L W ++QD+ V+ K+V PE + +N ++ +F++ EED
Sbjct: 192 DIFTNPILTKIAEKYGKSVAQVILRWLIEQDIIVLAKSVKPERMAQNLAVFDFELSEEDK 251
Query: 242 KALNQLSE 249
A+ L++
Sbjct: 252 SAIATLNQ 259
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 100 bits (239), Expect = 4e-20
Identities = 64/208 (30%), Positives = 108/208 (51%), Gaps = 19/208 (9%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLT 108
+++ D+ + AE A + L LD +Y+DL L+H+P D+ +TK +W +
Sbjct: 114 KIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP--------DQNDTK----AWKVME 160
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
+ GK+ A+G+SN+ +M++ + PAV Q E H Y F + + +
Sbjct: 161 QFVKAGKIRAIGLSNYHRKTFNRIMQAAT-ITPAVVQNEVHIYNQDKQTKAFLRNYGTQM 219
Query: 169 QAYCSFGGTSCSNNS----LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPE 224
+A+ GG + N L DP +VS A K +PAQVLL W LQ IP + +P
Sbjct: 220 EAWYPLGGRNSYGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRWQLQAGNIAIPGSSNPA 279
Query: 225 HIKENRSL-NFKIPEEDMKALNQLSEKN 251
HI+EN + +F + +++M L++L +K+
Sbjct: 280 HIRENIDIFDFALSDDEMATLSRLDKKS 307
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 100 bits (239), Expect = 4e-20
Identities = 69/207 (33%), Positives = 108/207 (52%), Gaps = 18/207 (8%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAE------DKRNTKMREL----SWCKLTEL 110
E A + +L+NL L+Y+DLYLIH+P G + E D + + +W ++ +L
Sbjct: 94 EGACKTTLQNLKLDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKL 153
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
D G V +GVSNF ++ +++ + PA NQ+E HPY QS + FC + I + A
Sbjct: 154 VDAGLVRNIGVSNFNAKQVQRVLDVAR-IPPATNQIECHPYLHQSKITTFCAEKGIIVTA 212
Query: 171 YCSFGG-----TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
Y G + L++D V A K + AQ+L+ + +Q VIPK+V E
Sbjct: 213 YSPLGSPARPWVKADDPVLMDDATVGQLAKKHGKSAAQILIRYQIQLGHVVIPKSVTKER 272
Query: 226 IKENRSL-NFKIPEEDMKALNQLSEKN 251
I N + +F++ E+DMK L L E+N
Sbjct: 273 IASNFDVFSFQLDEDDMKQLAGL-ERN 298
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 99 bits (238), Expect = 6e-20
Identities = 65/191 (34%), Positives = 98/191 (51%), Gaps = 7/191 (3%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A ++SL L L YVDLYLIH P + + +W + E G ++GVS
Sbjct: 115 ALRESLTKLGLSYVDLYLIHSPEATNENGDPVDIDVLN--TWNGMEEAKKLGLAKSIGVS 172
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG---GTSC 179
NF A L+ L+ ++ VPAVNQ+E HP TQ L + I + AY FG
Sbjct: 173 NFDTALLDRLIAGSN-TVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFGFYVSRGS 231
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
NN + ND V A K T QVL+ + L++ + IPK+ + + I+EN + +F++
Sbjct: 232 HNNPVKNDRTVADIARKYNKTVNQVLVRYLLERSLIPIPKSTNQQRIRENIDVFDFQLSP 291
Query: 239 EDMKALNQLSE 249
ED+ A+ +L +
Sbjct: 292 EDINAIGKLDK 302
Score = 34.3 bits (75), Expect = 3.2
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
LN+G +PS+ LGT+ V Q V +A++AGYR
Sbjct: 29 LNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYR 64
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 99 bits (238), Expect = 6e-20
Identities = 65/199 (32%), Positives = 109/199 (54%), Gaps = 21/199 (10%)
Query: 66 KSLENLDLEYVDLYLIHFP---------GGAKLPAEDKRNT------KMRELSWCKLTEL 110
K++E+L + Y+DLYLIH+P G P D+ +RE +W ++ +L
Sbjct: 108 KTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRE-TWQEMEKL 166
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
+ G V ++GVSNF V +L L+ + + P VNQVE HPY TQ L ++C ++ I L A
Sbjct: 167 VELGLVKSIGVSNFNVQNLVDLL-TYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVA 225
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
Y G C ++ ++ S A K + + A V+ W Q+ +A IPK+ + I EN
Sbjct: 226 YSPLGQGKC---DFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENF 282
Query: 231 SL-NFKIPEEDMKALNQLS 248
++ +F++ +D++ +N L+
Sbjct: 283 NIFDFQLSNDDIEKINSLN 301
Score = 36.7 bits (81), Expect = 0.60
Identities = 18/38 (47%), Positives = 23/38 (60%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
F LN+G +PSIGLGTY V ++ AL+ GYR
Sbjct: 17 FKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYR 54
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 99 bits (238), Expect = 6e-20
Identities = 67/219 (30%), Positives = 111/219 (50%), Gaps = 22/219 (10%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
E+A + SL+ L L+YVDLYL H P K + + K+ ++ W ++Y G A+G
Sbjct: 93 EEALRNSLKRLRLDYVDLYLAHIPASTKDDGSFRSDVKVEDI-WRGFEKVYGLGLTKAIG 151
Query: 121 VSNFTVAHLEGLMESNHGLVPA-VNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG--- 176
VSNF + + +M N VP +Q+E H Y Q + + CK+H+I + AY + G
Sbjct: 152 VSNFNESQIVRIM--NIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGR 209
Query: 177 -------------TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHP 223
++ ++ + +ND V + A K TPAQ+LL ++ + VIPK +P
Sbjct: 210 MSVVGSNGRPLFESTQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNP 269
Query: 224 EHIKENRSL-NFKIPEEDMKALNQLSE-KNVKYAWDPSI 260
E +KEN ++ +F I ++ L K + W P++
Sbjct: 270 ERMKENINIFDFNISNAEVNLLEAHERTKQERLFWWPNV 308
Score = 37.9 bits (84), Expect = 0.26
Identities = 22/49 (44%), Positives = 32/49 (65%), Gaps = 5/49 (10%)
Query: 1 MASSDPIIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
M+S PI F L+NG++MPSIGLGT+++ + V+ A+ AGYR
Sbjct: 1 MSSKVPI----FTLSNGVLMPSIGLGTWQMTGEE-GKTVIRNAVLAGYR 44
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 99.5 bits (237), Expect = 7e-20
Identities = 76/222 (34%), Positives = 115/222 (51%), Gaps = 27/222 (12%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAK-------------LPAEDKRNTKMRELS--WCKL 107
A+ + L++ LEY DLYLIHFP + +P DK N + + W ++
Sbjct: 94 AFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHECWAEM 153
Query: 108 TELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHIT 167
+L +GV+NF + L+ S + PAV Q+E HP Q L K+ ++ I
Sbjct: 154 EKLVQAKLTRNIGVANFNCQAILDLL-SYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQ 212
Query: 168 LQAYCSFGGTS----CSN----NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPK 219
+ AY SFG TS C + +SLL + V S A K Q+LL +AL +++AVIPK
Sbjct: 213 VTAYSSFGPTSYVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRYALDRNIAVIPK 272
Query: 220 AVHPEHIKENRS-LNFKIPEEDMKALNQLSEKNVKYAWDPSI 260
+VH + +K N LN ++ ++D K LN L + N ++ DP I
Sbjct: 273 SVHEDRMKSNLDILNIQLDQDDRKILNSL-KTNQRFN-DPMI 312
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 99.5 bits (237), Expect = 7e-20
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 14/192 (7%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKV 116
G A +SL L L+ VDLYL+H+P PA D +W K+ EL G
Sbjct: 83 GDEPAAAIAESLAKLALDQVDLYLVHWP----TPAADNYVH-----AWEKMIELRAAGLT 133
Query: 117 NAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG 176
++GVSN V HLE ++ + G+VPAVNQ+E HP Y Q + + H + ++ S+G
Sbjct: 134 RSIGVSNHLVPHLERIVAAT-GVVPAVNQIELHPAYQQREITDWAAAHDVKIE---SWGP 189
Query: 177 TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFK 235
L V + A TPAQ +L W LQ+ V PK+V E ++EN + +F
Sbjct: 190 LGQGKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFD 249
Query: 236 IPEEDMKALNQL 247
+ + ++ A++ +
Sbjct: 250 LTDTEIAAIDAM 261
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/39 (38%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
+ VLN+G +P +G G +++ +D + V+ ALE GYR
Sbjct: 5 SIVLNDGNSIPQLGYGVFKVPPAD-TQRAVEEALEVGYR 42
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 99.1 bits (236), Expect = 1e-19
Identities = 61/197 (30%), Positives = 107/197 (54%), Gaps = 19/197 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A++++L NL L+Y+DLYLIH+P K R+ SW + L+D+ + ++GV+
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVAGKY----------RD-SWRAMERLHDEKLIKSIGVA 141
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF HL L+ + + P +NQVE HP Q+ L K+ + +I A+ + +
Sbjct: 142 NFKQHHLSDLLVAANEK-PVLNQVETHPLLPQNDLRKYLAEQNIAHAAW-----SPLAKG 195
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLN-FKIPEEDM 241
L+ +PV+ A K + + QV+L W L ++ + PK++ I+EN L+ F++ DM
Sbjct: 196 ILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFPKSITSSRIEENSRLSYFQLDASDM 255
Query: 242 KALNQLSEKNVKYAWDP 258
+ +++L E + DP
Sbjct: 256 EKIDRL-ETGKRVGPDP 271
Score = 35.5 bits (78), Expect = 1.4
Identities = 13/39 (33%), Positives = 24/39 (61%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
+L +P IGLG +++ + + + V+ A+E GYR+F
Sbjct: 10 ILPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLF 48
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 99.1 bits (236), Expect = 1e-19
Identities = 65/195 (33%), Positives = 102/195 (52%), Gaps = 10/195 (5%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRN-----TKMREL-SWCKLTELYDDG 114
E+A + SL NL LEYVDLYL+H P G K + + T + L +W ++ +L D G
Sbjct: 93 ERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLG 152
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
++G+SNF A E ++ +N + P VNQVE HP + Q L + K+H + + AYC
Sbjct: 153 LTRSIGLSNFNAAQTERVL-ANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPL 211
Query: 175 GGTSCSNN--SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
+ L D + A K T AQ+ L + +Q V +PK+ + I+EN R
Sbjct: 212 ARPQPARQWPPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRV 271
Query: 232 LNFKIPEEDMKALNQ 246
+F++ +D+ + Q
Sbjct: 272 FDFELSPDDVAGMEQ 286
Score = 36.3 bits (80), Expect = 0.79
Identities = 18/39 (46%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T LNNG MP++GLGT++ +SD +AL+ GYR
Sbjct: 7 TIRLNNGREMPTLGLGTWKSFESD-AYHSTRHALDVGYR 44
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 98.7 bits (235), Expect = 1e-19
Identities = 75/260 (28%), Positives = 132/260 (50%), Gaps = 30/260 (11%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSD-HGSRAEQAYQKSLENLD 72
LNNGI MP +G G Y+I QVV+ LE GYR+ + +G+ EQA ++++ +
Sbjct: 7 LNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGN--EQAVGDAIKHSN 64
Query: 73 LEYVDLYLI------HFPGGAKLPAEDKRNTKMR----EL------------SWCKLTEL 110
+ D+++ + L A D K++ +L +W L L
Sbjct: 65 VPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYNDYYGTWRALERL 124
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
Y +G++ A+GVS+F L L+ N + PAVNQ+E + + + ++ ++ + +A
Sbjct: 125 YQEGRIRAIGVSSFWNERLADLITFN-DVKPAVNQIETNVWNQEWKSQQYMEKEGVQPEA 183
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
+ F + N + +P++ A K T AQV+L W LQ++ VIPK+VH + + EN
Sbjct: 184 WAPFAEGA---NHIFTNPLLEEIAEKHHKTTAQVMLRWFLQRNYVVIPKSVHKKRLAENY 240
Query: 231 SL-NFKIPEEDMKALNQLSE 249
+ +F++ +DMK + L +
Sbjct: 241 DVFDFELDADDMKKIKTLDQ 260
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 97.9 bits (233), Expect = 2e-19
Identities = 64/203 (31%), Positives = 104/203 (51%), Gaps = 19/203 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAE-------DKRNTKMREL----SWCKLTELY 111
A + S+ NL ++Y++LYL+H+P K ++ D ++ +W + L
Sbjct: 93 ACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLV 152
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
D+G A+GVSNF + L+ S L P V Q+E HPY +Q L C + I + AY
Sbjct: 153 DEGLCQAIGVSNFNEQQMNRLL-SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAY 211
Query: 172 CSFGGTSCSNNS-----LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
G LL P +++ A K E T AQVLL + Q + VIP++V +H+
Sbjct: 212 SCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHM 271
Query: 227 KEN--RSLNFKIPEEDMKALNQL 247
+N R +F++ +D++A+N+L
Sbjct: 272 LDNFKRIWDFELAVDDIQAINEL 294
Score = 39.5 bits (88), Expect = 0.085
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
F+L+NG MP +GLGT+R ++V Q V A++ GYR F
Sbjct: 6 FLLSNGKNMPMLGLGTWR-SPPEVVTQAVKDAIDIGYRHF 44
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 97.9 bits (233), Expect = 2e-19
Identities = 68/198 (34%), Positives = 100/198 (50%), Gaps = 19/198 (9%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGA------KLPAEDKRNTKMRELS--WCKLTELYDDGKV 116
QKSL+NL L YVDLYL+H+P G +L A++ ++ W + GK
Sbjct: 109 QKSLDNLRLPYVDLYLVHYPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKT 168
Query: 117 NAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG 176
+G+SNF ++ +++ + PAV QVE H Y Q +L FC QH I + A+C GG
Sbjct: 169 KNIGLSNFNADQVQRIIKGCQ-VRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGG 227
Query: 177 -----TSCSN----NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIK 227
S LL DP V+ A TPAQVLL + Q +V IPK+ +P +
Sbjct: 228 PFRLIRKASRPGEVKLLLEDPQVLDVATAHHKTPAQVLLRYLHQINVIPIPKSANPTRLF 287
Query: 228 ENRSL-NFKIPEEDMKAL 244
+N + +F++ +M L
Sbjct: 288 QNTQIFDFELTSAEMSRL 305
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 97.5 bits (232), Expect = 3e-19
Identities = 63/210 (30%), Positives = 107/210 (50%), Gaps = 22/210 (10%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAK-----LPAEDKRNTKM-----RELSWCKLTEL 110
E ++SL++L L+YVD+YLIH P K +DK + + W +
Sbjct: 110 ETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQ 169
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
+G+ ++G+SNF + + + +N + P+ QVE H Y Q L KFCK+H+I + A
Sbjct: 170 VKEGRAKSIGLSNFNQSQVLNIY-NNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTA 228
Query: 171 YCSFG----------GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
Y G GT +L+ P++ S A K +P Q+LL +Q+ + IPK+
Sbjct: 229 YAPLGSHNARLNLHRGTPKELPALVELPLIKSLAAKYNKSPGQILLRHTIQEGLVAIPKS 288
Query: 221 VHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
+ + K N + +FK+ +E+MK ++ L +
Sbjct: 289 SNAQRQKSNIDIFDFKLTDEEMKKIDALDK 318
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 97.5 bits (232), Expect = 3e-19
Identities = 56/176 (31%), Positives = 98/176 (55%), Gaps = 15/176 (8%)
Query: 75 YVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLME 134
YVDL L+H PG P+ + R++ W + + + +GVSNF V HL+ + E
Sbjct: 111 YVDLLLMHVPG----PSREHRHSL-----WEAMERAKREARARNIGVSNFRVRHLDEMKE 161
Query: 135 SNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTA 194
P+VNQ+E HP+ Q + K+C+ + I ++AY + + + L DP+V +
Sbjct: 162 YATEWPPSVNQIELHPWCQQKEVVKYCQDNEIIIEAY-----SPLATGARLEDPLVEGIS 216
Query: 195 LKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
K + + AQVL+ ++LQ+ +PK+ P+ I EN ++ +F + E+DM+ L+ L +
Sbjct: 217 TKHDKSHAQVLIRYSLQKGWVPLPKSSRPDRISENFNVFDFVLDEDDMETLDDLDK 272
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 97.5 bits (232), Expect = 3e-19
Identities = 64/208 (30%), Positives = 108/208 (51%), Gaps = 17/208 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAE---DKRNTKMREL------SWCKLT 108
++A + L +L L YVDL LIH+P G AE N KMR +W
Sbjct: 87 AKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFE 146
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
GK ++G+SNFT + ++ + ++ + PA QVE HPY+TQ L +FCK+ I +
Sbjct: 147 AAQKAGKCRSIGLSNFTHSQIQRVWDAAE-VKPACLQVELHPYFTQVKLREFCKEKGIVV 205
Query: 169 QAYCSFGGTSCS------NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVH 222
Y G + + ++L + VV A TPAQ++L W + ++ IPK+V
Sbjct: 206 VGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVT 265
Query: 223 PEHIKENRSL-NFKIPEEDMKALNQLSE 249
P+ I EN ++ +F++ E++ ++ +++
Sbjct: 266 PQRISENLAVFDFQLTAEEISKIDGINK 293
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 97.1 bits (231), Expect = 4e-19
Identities = 61/198 (30%), Positives = 100/198 (50%), Gaps = 10/198 (5%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A +++L L+YVDL+L+H+P NT E +W E+ G ++G+S
Sbjct: 121 AMKETLNKTGLDYVDLFLMHWPIALNEDYSHS-NTDYLE-TWRATEEMVKLGYTKSIGLS 178
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS-- 180
NF + +++ + P Q+E HP Q L + K I + Y FG
Sbjct: 179 NFNKLQVATVLQECT-IKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLVKRFG 237
Query: 181 ---NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKI 236
++DPV+ S A K E TPAQ++L W + + V IPK V P+ + EN ++ +FK+
Sbjct: 238 MDLPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINIFDFKL 297
Query: 237 PEEDMKALNQLSEKNVKY 254
EE+++ +NQ + N +Y
Sbjct: 298 KEEEIEKINQFN-SNTRY 314
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 97.1 bits (231), Expect = 4e-19
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 18/191 (9%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R +A + LE L EY+DL L+H+ P D T + L L DDG V
Sbjct: 93 RLIEAAKGCLERLGTEYLDLLLVHWWN----PLADMEET------FNALNTLVDDGLVGQ 142
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF++ L+ M + + A NQ+E+HPY+ L +FC+ + +T+ AY +
Sbjct: 143 IGVSNFSIKELKQAMRLSDAPI-ATNQIEYHPYWGDEELVRFCQDNDVTVTAY-----SP 196
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQD-VAVIPKAVHPEHIKENRSL-NFKI 236
+ + D V+ S + + AQV + W +QQ+ V IPKA P+HI+ N + +F++
Sbjct: 197 LAEGRAVEDDVLRSIGDRYGKSAAQVSIRWLIQQENVVTIPKAATPKHIEANIDVFDFEL 256
Query: 237 PEEDMKALNQL 247
+ DM+ + +L
Sbjct: 257 TDRDMRRIRKL 267
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 96.7 bits (230), Expect = 5e-19
Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 19/197 (9%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFT 125
KSL+ L Y+DL L+H P G A W L LY G V A+GVSNF
Sbjct: 91 KSLKKLQTNYIDLVLLHQPFGDYYSA------------WKALEVLYKKGIVKAIGVSNFE 138
Query: 126 VAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLL 185
L + + P +NQ+E HP + + ++ + ++++ SFG + + ++
Sbjct: 139 ADRLVDFC-LHVDVKPVINQIELHPLRQRIEDLHWNNKYGVAVESWASFGRAT---SEIM 194
Query: 186 NDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKAL 244
+P++VS A K T Q++L W +QQ++ VIPK V +KEN + +F+I ++DM +
Sbjct: 195 ENPILVSLAEKYNKTVPQIILRWLIQQNIVVIPKTVTESRLKENMDIFDFEISDDDMDLI 254
Query: 245 NQLSEKNV--KYAWDPS 259
+++ K+ DPS
Sbjct: 255 KTINQNKTVSKHHHDPS 271
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 96.7 bits (230), Expect = 5e-19
Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFT 125
+SL + L+Y DL LIH+P G + +W L Y GK A+G+SNF
Sbjct: 88 ESLRRIGLDYFDLVLIHWPMGHDID------------TWHALEAAYKAGKTRAIGISNFN 135
Query: 126 VAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLL 185
L+ + + P V+Q+E H + Q +++F ++ +I ++Y G +L+
Sbjct: 136 SRQTLDLIHQS-SVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN---GQQNLI 191
Query: 186 NDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKAL 244
++PV+ + K +P QV+L + +Q DV IP++ +P HIK N + +F++ +D+K L
Sbjct: 192 SNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPRSTNPAHIKSNIDIFDFELDNDDLKRL 251
Query: 245 NQLSEKNVKYAW 256
L E+ W
Sbjct: 252 RVLDERKPIDGW 263
Score = 34.3 bits (75), Expect = 3.2
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQ 62
LNN + +P G GTY I D Q V A E GYR+ + + +Q
Sbjct: 6 LNNDVKIPIFGFGTYEI-SPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQ 53
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 96.3 bits (229), Expect = 7e-19
Identities = 57/188 (30%), Positives = 99/188 (52%), Gaps = 17/188 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
++ +SL+ L L+YVDL LIH P A W + EL GK+ A+GVS
Sbjct: 88 SFDRSLKRLGLDYVDLLLIHQPFNDVYGA------------WIAMEELQASGKIRAIGVS 135
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF+ + L N + P VNQ+E +P+ Q++ ++ + ++A+ F N
Sbjct: 136 NFSPDRVIDLAAFNE-VTPQVNQIEVNPFQQQTANLAILRKEGVAIEAWAPFAE---GKN 191
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
+ N+PV+ K + AQV+L W ++QD+ V+ K+V PE + +N ++ +F++ E D
Sbjct: 192 DIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEADK 251
Query: 242 KALNQLSE 249
+ + L +
Sbjct: 252 EEIAGLDQ 259
Score = 37.9 bits (84), Expect = 0.26
Identities = 17/39 (43%), Positives = 24/39 (61%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T LNNG+ +P +G GTY+I + V A++AGYR
Sbjct: 3 TVKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYR 41
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 96.3 bits (229), Expect = 7e-19
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 18/195 (9%)
Query: 55 DHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD 113
D+G A +A +SL L L+Y+DLYLIH P G +P +W +
Sbjct: 82 DYGFDAASRAIDRSLTKLRLDYIDLYLIHQPYG-DVPG-----------AWQAMEAAQKA 129
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
GK+ ++GVSN T + + +PAVNQVE++PY+ Q L + + L+A+
Sbjct: 130 GKLKSIGVSNMTPTLWQKFVPQFE-TIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAP 188
Query: 174 FGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
G N +L +P++ A+K Q++L + Q+ V V PK+VH IK NR +
Sbjct: 189 LGQ---GNQALFKEPIIQQLAIKYHKDAGQIILRFEHQEGVIVFPKSVHSARIKSNRDIF 245
Query: 233 NFKIPEEDMKALNQL 247
+F++ +M L L
Sbjct: 246 DFELTSTEMAQLRAL 260
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 96.3 bits (229), Expect = 7e-19
Identities = 65/205 (31%), Positives = 108/205 (52%), Gaps = 20/205 (9%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+A++A ++S+ DL Y+DL L+H P G K + R +W L E G V +
Sbjct: 102 KAKEAIEQSVAATDLGYIDLILLHAPYGGK---------EGRLGAWRALVEAQKAGHVRS 152
Query: 119 VGVSNFTVAHLEGLME---SNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
+GVSN+ + HLE L E S G +V Q E HP+ + + + K+ ++ ++AY
Sbjct: 153 IGVSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAWLKKRNVVIEAY---- 208
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
+ L++PV+ + A K T AQ+L+ W+LQ+ +PK+V I EN + +F
Sbjct: 209 -SPLVQAQRLDEPVLQNLAKKHNKTGAQILIRWSLQKGYVPLPKSVTDSRIVENTQVFDF 267
Query: 235 KIPEEDMKALNQLSEKNVKYAWDPS 259
++ EDM++LN + WDP+
Sbjct: 268 ELSGEDMESLN--TGIYAPVCWDPA 290
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 96.3 bits (229), Expect = 7e-19
Identities = 60/188 (31%), Positives = 99/188 (52%), Gaps = 10/188 (5%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A +SL L L YVDLYLIH P AK E ++ +W + ++ GK A+GVS
Sbjct: 101 AIDQSLRKLQLNYVDLYLIHSPFFAKSDGELQQ-------AWAAMEKVQQAGKAKAIGVS 153
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
N+ +HLE +++ + P +NQ+E HPY Q L +F ++ I + +Y +
Sbjct: 154 NYHQSHLEATLKTAV-IAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPLTPILRAPG 212
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQ-DVAVIPKAVHPEHIKENRSLNFKIPEEDM 241
+ DP V A K +VT +VLL W++ + DVAV + + + L F++ E++
Sbjct: 213 GPV-DPKVSELAAKYKVTEGEVLLRWSIDRGDVAVTTSSKESRLQEFLQVLTFQLTPEEV 271
Query: 242 KALNQLSE 249
+ ++QL +
Sbjct: 272 REISQLGQ 279
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 95.9 bits (228), Expect = 9e-19
Identities = 61/206 (29%), Positives = 109/206 (52%), Gaps = 18/206 (8%)
Query: 53 PSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY- 111
P + E+A +++L L+ +Y+D+ L+H PG + A K E Y
Sbjct: 109 PGAQFANPEKAIEEALNKLNTDYIDMMLLHHPGENDVKAY-------------KAIEKYI 155
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
+ GK+ +VG+SN+ + + + + + P++ Q E H YY + + + +I +QA+
Sbjct: 156 EKGKIKSVGLSNWYIKEINSFLPQIN-IKPSLIQNEIHIYYQEKEVVPYMHNLNIAMQAW 214
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
FGG S+LN+P +VS A T AQ++ W LQ+ + I + +P HIKEN S
Sbjct: 215 YPFGGRG-HTFSVLNNPTIVSIAKDHNKTSAQIISRWLLQRGIITIVGSSNPIHIKENIS 273
Query: 232 L-NFKIPEEDMKALNQLSEKNVKYAW 256
+ +F++ ++M+ + L +KN K+ W
Sbjct: 274 VFDFELSNQEMELIASL-DKNEKHDW 298
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 95.9 bits (228), Expect = 9e-19
Identities = 69/212 (32%), Positives = 111/212 (52%), Gaps = 28/212 (13%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP-------------GGAKLPAEDKRNTKMRE-----L 102
+++ +SL+ L LEYVDL L H+P G K P +D T
Sbjct: 110 DRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLE 169
Query: 103 SWCKLTELY---DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYK 159
++ +L ++Y +D +V A+GVSNF++ +LE L++ + P VNQVE HP+ Q L K
Sbjct: 170 TYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECR-VKPTVNQVETHPHLPQMELRK 228
Query: 160 FCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPK 219
FC H I L AY G N L P+V A K VT +L+ + ++Q VIP+
Sbjct: 229 FCFMHDILLTAYSPLGSHGAPN---LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPR 285
Query: 220 AVHPEHIKENRSLNF-KIPEEDMKALNQLSEK 250
+++P ++ + S+ F + +++++ LN EK
Sbjct: 286 SLNP--VRISSSIEFASLTKDELQELNDFGEK 315
Score = 34.3 bits (75), Expect = 3.2
Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQS-DIVMQVVDYALEAGYR 49
F LNNG+ +P++GLGT + Q V A++AGYR
Sbjct: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYR 63
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 95.1 bits (226), Expect = 2e-18
Identities = 71/230 (30%), Positives = 115/230 (50%), Gaps = 33/230 (14%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAK-LP------------AEDKRNTKMREL 102
H + A +K+L ++ L+Y+DLY IHFP K +P A+D++ + E
Sbjct: 85 HPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEA 144
Query: 103 ------SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSS 156
++ L E D+G + ++GVSNF + ++ L+ + P Q+E HPY TQ
Sbjct: 145 HVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCR-IKPVALQIEHHPYLTQEH 203
Query: 157 LYKFCKQHHITLQAYCSFGGTSCSNNSLL----------NDPVVVSTALKLEVTPAQVLL 206
L +FCK H I + AY SFG S L ND + + T +QVLL
Sbjct: 204 LVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLL 263
Query: 207 VWALQQDVAVIPKAVHPEHIKENRSL--NFKIPEEDMKALNQLSEKNVKY 254
WA Q+ +AVIPK+ E + N + F + E+++K ++ L+ N+++
Sbjct: 264 RWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALN-ANIRF 312
Score = 39.9 bits (89), Expect = 0.064
Identities = 21/71 (29%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAE--QAYQKSLEN 70
LNNG+ MP +GLG ++I + Q+ + A++ GYR+F D+G+ E + +K++
Sbjct: 7 LNNGLKMPLVGLGCWKIDKKVCANQIYE-AIKLGYRLFDGACDYGNEKEVGEGIRKAISE 65
Query: 71 LDLEYVDLYLI 81
+ D++++
Sbjct: 66 GLVSRKDIFVV 76
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 94.7 bits (225), Expect = 2e-18
Identities = 62/188 (32%), Positives = 95/188 (50%), Gaps = 14/188 (7%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
+ + Q+SL L +YVDL LIH+P K MRE L + G A+G
Sbjct: 76 QPSLQESLRKLGTDYVDLTLIHWPS-------PKDQVPMREYLEA-LADAKAQGLTRAIG 127
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
VSNFT+A +E A NQ+E HPY +L F ++ I + +Y + +
Sbjct: 128 VSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRTLIAFLREQGIHVTSYMTL-----A 182
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEE 239
+L DPV+ + A + + TPAQV L WALQQ +VIP + +++ N ++ + + E+
Sbjct: 183 VGEVLKDPVIQAIARRHDATPAQVTLAWALQQGYSVIPSSTKRANLESNLKAQSLHLSEQ 242
Query: 240 DMKALNQL 247
DM + L
Sbjct: 243 DMAEIAAL 250
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 94.3 bits (224), Expect = 3e-18
Identities = 62/192 (32%), Positives = 99/192 (51%), Gaps = 20/192 (10%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A ++SLENLD +YVDL L+H+P ++P + L EL G +GVS
Sbjct: 93 AAKRSLENLDTDYVDLLLLHWPDD-RVPLSETIPA---------LCELQKQGLTRNIGVS 142
Query: 123 NFTVAHLEGLMESNHGLVP-AVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
NF +A++ + + VP VNQVE+HP+ Q +L F HHI L+AY +
Sbjct: 143 NFNIANI--IEAKRYADVPIVVNQVEFHPFIKQKTLQTFLNNHHILLEAYSPLARGDVFD 200
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAV-IPKAVHPEHIKEN-RSLNFKIPEE 239
N ++ D A K +T AQV L W L + IPK +PEH++ N ++ ++ +
Sbjct: 201 NKIIKD-----IADKHGITAAQVSLAWILSDKHRIAIPKTSNPEHLQGNLDAIKVELSAD 255
Query: 240 DMKALNQLSEKN 251
+++ + L+ +
Sbjct: 256 ELEKIGSLARSD 267
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 94.3 bits (224), Expect = 3e-18
Identities = 60/205 (29%), Positives = 107/205 (52%), Gaps = 12/205 (5%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMREL-------SWCKLTELYDDGK 115
A + +L+ L +EYVDLYLIH+P + E+ +L +W + E Y G
Sbjct: 100 ALKTTLKKLGMEYVDLYLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGL 159
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
++G+ N+ L L+E + PAVNQVE +P + Q +L +FCKQ I + A+ G
Sbjct: 160 AKSIGICNYGTKKLTKLLEIAT-IPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLG 218
Query: 176 GTSC--SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL- 232
+ +++ + ++ A T AQV L W QQ + + K+ + E +K+N +
Sbjct: 219 AYKIFWGSGAVMENQILQDIATAKGKTIAQVALRWVYQQGSSAMAKSFNKERMKQNLEIF 278
Query: 233 NFKIPEEDMKALNQLSEKNVKYAWD 257
+F++ EE+++ + Q+ ++ +Y D
Sbjct: 279 DFELSEEELEKIKQIPQRR-QYTGD 302
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 93.9 bits (223), Expect = 4e-18
Identities = 75/267 (28%), Positives = 133/267 (49%), Gaps = 32/267 (11%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSD-HGSRAE--QAYQKSLEN 70
LNNG MP +G G ++I + VVD A+ AGYR + +G+ AE Q +++ N
Sbjct: 6 LNNGAQMPQLGFGVFQIPAEETKQAVVD-AINAGYRSIDTARVYGNEAETGQGVNEAIAN 64
Query: 71 LDLEYVDLYLI------HFPGGAKLPAED----KRNTKMREL------------SWCKLT 108
+ +L+L F A A D K T +L ++ L
Sbjct: 65 AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYGDVYGAYKALA 124
Query: 109 ELYDDGKVNAVGVSNFTVA---HLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHH 165
E DGKV ++G+SNF A ++++ + VP ++Q+E+HPYY + + ++
Sbjct: 125 EAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEKVARQLHDKYG 184
Query: 166 ITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
+ ++A+ G T+ + + P +V A K + + QV+L W +Q ++ + K+V+P
Sbjct: 185 VQIEAWGPLGRTA-NKYDTFHQPELVEIAAKHDKSVGQVVLRWIMQSNIITVAKSVNPSR 243
Query: 226 IKENRSL-NFKIPEEDMKALNQLSEKN 251
+ EN + NF++ ++DMK + L +KN
Sbjct: 244 MAENIDIFNFELDDDDMKKIETL-DKN 269
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 93.9 bits (223), Expect = 4e-18
Identities = 63/189 (33%), Positives = 90/189 (47%), Gaps = 16/189 (8%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A +A + SLE L L+Y+DL+LIH+P + T + LT L D G V A+
Sbjct: 90 ARRACEASLERLGLDYIDLFLIHWP-------NPDQGTYVEAFE--GLTRLLDAGLVRAI 140
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
G SNF HL L + G VP VNQ++ PY+ + + I +++ G
Sbjct: 141 GTSNFLPHHLNDLFAA--GFVPHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIGRA-- 196
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
+L DP + A TPAQ++L W +Q PK+ PE +N + F + E
Sbjct: 197 --GEMLADPAITRIAEAHGKTPAQIVLRWQVQSGFVPAPKSADPERQAQNLDVFGFALTE 254
Query: 239 EDMKALNQL 247
DM ALN L
Sbjct: 255 SDMAALNGL 263
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDH 56
T L NG+ MP +GLGT+ + D + V A+E GYR+ +++
Sbjct: 9 TVTLANGVEMPQLGLGTWPM-TDDEAAKAVATAIETGYRLIDTAEN 53
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 93.9 bits (223), Expect = 4e-18
Identities = 64/205 (31%), Positives = 102/205 (49%), Gaps = 19/205 (9%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP---------GGAKLPAEDKRNTKMREL----SWCKL 107
E ++L L L YVDL+LIH P G +P ++K + ++ ++ +
Sbjct: 82 EPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKGKIQYEQIDILETYHAM 141
Query: 108 TELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHIT 167
E G +GVSNF++ LE + N + P NQVE + Y L +C+ H+I
Sbjct: 142 EECQKKGLTRHIGVSNFSIEQLERIW-FNCEIKPYANQVECNIYRQFKPLLSYCESHNIY 200
Query: 168 LQAYCSFGGTSCSN---NSLLNDPVVVSTALKLEVTPAQVLLVWALQQD--VAVIPKAVH 222
L A+ + G SLL DPVV A + + T AQ+ L + Q+ +IP +++
Sbjct: 201 LMAHTTIGHPPLKGPFGTSLLEDPVVKQVASEAKKTSAQICLKFLQQKSKMYILIPMSMN 260
Query: 223 PEHIKENRSLNFKIPEEDMKALNQL 247
P++IK N L+F + E+ MK L +L
Sbjct: 261 PKNIKSNYELDFTLTEQQMKKLEEL 285
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 93.9 bits (223), Expect = 4e-18
Identities = 57/196 (29%), Positives = 102/196 (52%), Gaps = 12/196 (6%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
++ L+ L +Y DL+LIH +P D N + + +W L +LY+ G A+GV
Sbjct: 95 ESISNQLKTLQTDYFDLFLIH------VPPNDDINYDLAK-AWGVLEQLYEKGLAKAIGV 147
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSS--LYKFCKQHHITLQAYCSFGGTSC 179
SN + A LE +++ + P VNQ+E+HP + + + FCKQH I ++ Y
Sbjct: 148 SNHSPAELETIIKVAK-IKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLASNEL 206
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
L D VV + A V+P VLL WA Q+ + I + + KE ++ +FK+ +
Sbjct: 207 EGEKPL-DAVVANVAKNHNVSPGSVLLRWATQKGIVPITTSANAGRQKEALAIFDFKLSD 265
Query: 239 EDMKALNQLSEKNVKY 254
+++ ++++ ++ +Y
Sbjct: 266 GEVEEISKVGAESPRY 281
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 93.9 bits (223), Expect = 4e-18
Identities = 65/205 (31%), Positives = 107/205 (52%), Gaps = 17/205 (8%)
Query: 56 HG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDG 114
HG + A + + SL+ L L+ +DL LIH+P + D +W + + + G
Sbjct: 82 HGRAEAVDSIRGSLDRLGLDVIDLQLIHWPNPSVGRWLD---------TWRGMIDAREAG 132
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
V ++GVSNFT L+ L++ G+ PAVNQVE HPY+ Q++L F +H I +++
Sbjct: 133 LVRSIGVSNFTEPMLKTLIDET-GVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSPL 191
Query: 175 GGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-N 233
S LL + ++ A+ VTP QV+L W +Q IPK+ P+ +EN +
Sbjct: 192 ARRS----ELLTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIPKSADPDRQRENADVFG 247
Query: 234 FKIPEEDMKALNQLSEKNVKYAWDP 258
F + + + A++ L E+ + DP
Sbjct: 248 FALTADQVDAISGL-ERGRLWDGDP 271
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 93.9 bits (223), Expect = 4e-18
Identities = 65/213 (30%), Positives = 110/213 (51%), Gaps = 11/213 (5%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHF-----PGGAKLP--AEDKRNTKMRE 101
+++ +H A +KSL+ L LEY+DLYLIH+ PG P ED ++
Sbjct: 88 KLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKG 147
Query: 102 LSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
+ W + E G A+GVSNF+V L+ L+ S + P V+QVE + + Q L +FC
Sbjct: 148 V-WESMEECQKLGLTKAIGVSNFSVKKLQNLL-SVATIRPVVDQVEMNLAWQQKKLREFC 205
Query: 162 KQHHITLQAYCSF-GGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKA 220
K++ I + A+ G S N ++ + V+ A + AQV L W +Q V +PK+
Sbjct: 206 KENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKS 265
Query: 221 VHPEHIKENRSL-NFKIPEEDMKALNQLSEKNV 252
E + +N + ++ + E+D ++Q+S+ +
Sbjct: 266 YDKERMNQNLHIFDWALTEQDHHKISQISQSRL 298
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 93.5 bits (222), Expect = 5e-18
Identities = 58/192 (30%), Positives = 102/192 (53%), Gaps = 7/192 (3%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A + SL+ + L+++DL LIH P + + E+ + L + GKV ++
Sbjct: 95 ASASIDTSLKTMKLDFIDLMLIHSPQPWNSFRKGDYFKENVEV-YNALEDAQKAGKVRSI 153
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
GVSNF LE +++ N PA NQ+ H T +L +CK+ +I +AY +
Sbjct: 154 GVSNFLQKDLENILK-NCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAY-----SPI 207
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEE 239
++ LL DP V+ A K V+PAQ+ + + L+ + +PK+ P++I EN ++F +
Sbjct: 208 AHGELLKDPRVIELAKKYNVSPAQICIRYTLELGLVSLPKSKTPKYIAENAQVDFTFSKA 267
Query: 240 DMKALNQLSEKN 251
D++ L +L+ K+
Sbjct: 268 DLQTLKKLTFKD 279
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 93.5 bits (222), Expect = 5e-18
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 13/167 (7%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAED-------KRNTKMRE 101
+++ H + +++L + +EY+DLYLIHFP +L AED K + M +
Sbjct: 83 KLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVSMRL-AEDPESMTYSKDDLVMMD 141
Query: 102 LS--WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYK 159
+ W ++ E G A+GVSNF+ LE L+ S + PA NQVE HPY Q+ L +
Sbjct: 142 MEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLL-SFATISPAANQVEVHPYCRQNKLRE 200
Query: 160 FCKQHHITLQAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQV 204
FCK+ I L AY G GT SNN++++ P++ A++ T AQ+
Sbjct: 201 FCKEKGIQLCAYSPLGGKGTPWSNNAVMDCPLLKQIAMERGKTIAQI 247
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 93.5 bits (222), Expect = 5e-18
Identities = 66/222 (29%), Positives = 107/222 (48%), Gaps = 26/222 (11%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKL--------PAEDKRNTKMR------EL 102
G R E +K L + L+Y DL+++HFP K P N K+ +
Sbjct: 87 GDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQE 146
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
+W + L D ++GVSNF+ L L+ + PA Q+E HPY TQ L + +
Sbjct: 147 TWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR-IRPATLQIEHHPYLTQERLVTYAQ 205
Query: 163 QHHITLQAYCSFGGTSC---------SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQD 213
+ I + AY SFG S L + V+ A K TPAQVLL WA Q++
Sbjct: 206 KEGIAVTAYSSFGPLSFVELDLKDAHETPKLFDHDVIKGIAQKHGKTPAQVLLRWATQRN 265
Query: 214 VAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSEKNVKY 254
+AVIPK+ P + +N + + + +++ ++ L+ +N+++
Sbjct: 266 IAVIPKSNDPTRLAQNLDVTGWDLETSEIEVISSLN-RNLRF 306
Score = 37.5 bits (83), Expect = 0.34
Identities = 19/71 (26%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF-APSDHGSRAE--QAYQKSLEN 70
LN+G MP +G G +++ Q+ +A++AGYR+F D+G+ E + ++++
Sbjct: 8 LNSGYDMPLVGFGLWKVNNETCADQIY-HAIKAGYRLFDGACDYGNEVEAGKGVARAIQE 66
Query: 71 LDLEYVDLYLI 81
++ DL+++
Sbjct: 67 GIVKREDLFIV 77
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 93.1 bits (221), Expect = 6e-18
Identities = 55/191 (28%), Positives = 99/191 (51%), Gaps = 15/191 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
+A + ++SL + +Y+DLYLIH+P P + + +W L + G + +
Sbjct: 104 KAMETIEESLYRMQFDYLDLYLIHWPN----PQQG-----LYIEAWQALIDAQKKGYIRS 154
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF H+E L G++P +NQVE HPY+ Q+ + + I A+ G
Sbjct: 155 IGVSNFLPKHIETLRRET-GVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLGRA- 212
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
++L+D V+ A + T QV+L W +Q V IPKA ++ N+++ +F +
Sbjct: 213 ---KAILDDAVLKQIAQETSRTVVQVVLRWQVQMGVIPIPKAASDQNQMANQAIFDFSLS 269
Query: 238 EEDMKALNQLS 248
++ ++ +N L+
Sbjct: 270 DDQVQRINALT 280
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 93.1 bits (221), Expect = 6e-18
Identities = 64/203 (31%), Positives = 105/203 (51%), Gaps = 18/203 (8%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R +A +K LE L E+VD+ LIH+P P +D+ +W L EL D GK +
Sbjct: 82 RTLRAAEKCLERLGREHVDMLLIHWP----CPEKDQFVD-----TWKALIELRDAGKAKS 132
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG-GT 177
+GVSNF L+ +++ G+ PA+NQ+E HP + Q + K + I Q++ G G
Sbjct: 133 IGVSNFREEDLKRIIDET-GVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPLGQGK 191
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKI 236
SN V+ + A + V+L W +Q + IPKA +HI+ N ++L+F++
Sbjct: 192 GMSNE------VIEAIAEETGQPETAVILRWHIQHGLCPIPKASSRDHIEANFKALSFEL 245
Query: 237 PEEDMKALNQLSEKNVKYAWDPS 259
+E M ++ L + + DP+
Sbjct: 246 SDEQMGRIDALDDPKGRMGPDPA 268
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 93.1 bits (221), Expect = 6e-18
Identities = 64/202 (31%), Positives = 101/202 (50%), Gaps = 25/202 (12%)
Query: 53 PSD-HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAK----LPAEDKRNTKMRELS---- 103
P+D H E A + +L L L+Y+DLYLIH+P + +++ R + R+ +
Sbjct: 98 PTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAID 157
Query: 104 --------WCKLTELYDDGKVNAVGVSNFTVAHLEGLM----ESNHGLVPAVNQVEWHPY 151
W + L D G V ++G++N T AH+ L+ E+ +P +NQVE HP
Sbjct: 158 TSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPG 217
Query: 152 YTQSSLYKFCKQHHITLQAYCSFGGTSCSN----NSLLNDPVVVSTALKLEVTPAQVLLV 207
L H + + AYC G +CS SLL+DPV+ S + +PA++LL
Sbjct: 218 IVDGDLIGCLGSHDMLMAAYCPLGMPTCSTPPGFQSLLDDPVLRSLSAFSGFSPARLLLN 277
Query: 208 WALQQDVAVIPKAVHPEHIKEN 229
W++ + VI K+ EHI+ N
Sbjct: 278 WSVDRHNVVIVKSASREHIRSN 299
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 93.1 bits (221), Expect = 6e-18
Identities = 56/191 (29%), Positives = 102/191 (53%), Gaps = 10/191 (5%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFT 125
K+L L ++YVDL+LIH P ++ + E +W L E GKV +G+SN
Sbjct: 109 KALAQLGVDYVDLFLIHSP----FFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISNAA 164
Query: 126 VAHLEGLMESNHG--LVPAVNQVEWHPYYTQSS--LYKFCKQHHITLQAYCSFGGTSCSN 181
+ HLE L ++ P VNQ+E+HP+ S + +FC++H I ++A+ +
Sbjct: 165 IPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLARVE 224
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+ L + + A K + T AQVLL + LQ+ + + + +KE+ +L +F++ +E+
Sbjct: 225 TNALAE-TLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEE 283
Query: 241 MKALNQLSEKN 251
+ +N++ + N
Sbjct: 284 VNEINKIGDAN 294
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 93.1 bits (221), Expect = 6e-18
Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 20/206 (9%)
Query: 56 HGSRAEQAY---QKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
+ S EQA+ + SL+ +EY DLYL+H G + +R+ W L +
Sbjct: 109 NNSSYEQAFVDLKGSLKRSGVEYFDLYLMHSAIGGPV---------IRKNVWKALCDAQS 159
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G V ++GVSNF H++ ++ L P VNQV+ HP+ + + C+Q+ I L+A+
Sbjct: 160 QGLVKSIGVSNFGKKHIQEFIDQKVPL-PTVNQVDLHPFMRHPEIVEICEQNEILLEAWG 218
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
+ + PVVV A + AQ++L W +Q VIPK+V + I N +
Sbjct: 219 PL-----ARAMRFDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVIPKSVSQKRIVSNSKI 273
Query: 233 -NFKIPEEDMKALNQLSEKNVKYAWD 257
+F++ E+MK L+ L E V WD
Sbjct: 274 FDFELSSEEMKELDGLDEYLVT-DWD 298
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 93.1 bits (221), Expect = 6e-18
Identities = 76/242 (31%), Positives = 108/242 (44%), Gaps = 22/242 (9%)
Query: 24 GLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDLEYV------- 76
G+G IR S + + V + AP D E SL+NL L YV
Sbjct: 65 GIGA-AIRASGVPREDVFVVTKLHNCFHAPED----VEVGMNMSLKNLGLGYVPYAYTKG 119
Query: 77 -DLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMES 135
+ + P G P D ++ + +W + L D GK +GVSNF+ L+ L+ S
Sbjct: 120 ENYSTVRKPDGK--PVVDIELSRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLL-S 176
Query: 136 NHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC------SNNSLLNDPV 189
+ P VNQVE +PY+ Q L +FC +H I + AY G T L D
Sbjct: 177 VCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHVTAYGPLGCTPVPYLIGRKTPGPLEDCT 236
Query: 190 VVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEEDMKALNQLSE 249
V + A + TPAQ++L + V+VIPK+ + I EN ++ ED AL QL
Sbjct: 237 VKAMAERYSRTPAQIILAHLIMLGVSVIPKSNNLSRISENFDCLVELSPEDHAALGQLMG 296
Query: 250 KN 251
N
Sbjct: 297 SN 298
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 92.7 bits (220), Expect = 9e-18
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 14/204 (6%)
Query: 63 AYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMREL----SWCKLTELYDD 113
A +KSLENL +Y+DL+L+H+P G A P + + + +W + E
Sbjct: 93 ACKKSLENLGFDYIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQ 152
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G ++G+SNF + L+ S+ + P NQVE Q L +FCK+H IT+ +
Sbjct: 153 GLARSIGLSNFNSEQIARLL-SSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSP 211
Query: 174 FG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
G G +L ++P + A K + TPA + + Q V IPK+V IKEN
Sbjct: 212 LGRPGNRHGIQNLWDEPQIQKLAQKYKKTPANIACRFIHQLGVTPIPKSVTKSRIKENLD 271
Query: 232 L-NFKIPEEDMKALNQLSEKNVKY 254
+ +F + E++ + ++ + N KY
Sbjct: 272 IFDFSLTPEEVSTIEKMGKHN-KY 294
Score = 89.4 bits (212), Expect = 8e-17
Identities = 60/202 (29%), Positives = 98/202 (48%), Gaps = 14/202 (6%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMREL--------SWCKLTE 109
S A ++SL +L L+Y+DLYLIH+P + +N + L +W + E
Sbjct: 348 SEVVPACKQSLNDLGLDYIDLYLIHWP--IRRYFRHNKNASGKLLLSDTDYLETWKGMEE 405
Query: 110 LYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQ 169
G ++GVSNF + L+E+ + P NQVE Q +L +FCK+H IT+
Sbjct: 406 CKRQGLARSIGVSNFNSEQITRLLEAAK-IKPVNNQVEVSLKLNQKALIEFCKKHDITVT 464
Query: 170 AYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIK 227
Y G G + +DP++ K TPAQ+ + Q IPK+V IK
Sbjct: 465 GYSPLGRPGNRYGITNAWDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIK 524
Query: 228 ENRSL-NFKIPEEDMKALNQLS 248
EN + +F + +E++ ++ ++
Sbjct: 525 ENFEIFDFSLTDEEINSIQSIA 546
Score = 38.7 bits (86), Expect = 0.15
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T N+G MP IGLGT+ + + V + V YA+E GYR
Sbjct: 5 TVTFNDGYKMPMIGLGTFLSKPGE-VAEAVKYAIEVGYR 42
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 92.3 bits (219), Expect = 1e-17
Identities = 59/199 (29%), Positives = 98/199 (49%), Gaps = 16/199 (8%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKV 116
G Q+ KSL +L +Y+DL LIH+P + +W L E D GK+
Sbjct: 108 GGTVRQSLDKSLADLGTDYIDLVLIHWPVKGHIKE-----------TWQILEEYVDKGKI 156
Query: 117 NAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG 176
++GVSNF HL+ L+E + P VNQ+E PY TQ + + + I ++A+ G
Sbjct: 157 RSIGVSNFNPHHLDELLEYAR-IRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAW---GP 212
Query: 177 TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFK 235
+L+DP + A + + AQV+L W +Q+ + IP+ + + EN R +F+
Sbjct: 213 LGQGVTGVLDDPAIGEIAARHGKSAAQVILRWHMQRGLVTIPRCDNDAYTDENIRIFDFE 272
Query: 236 IPEEDMKALNQLSEKNVKY 254
+ +M+ + L+ Y
Sbjct: 273 LSPSEMEIITGLNRNQRAY 291
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 91.9 bits (218), Expect = 1e-17
Identities = 68/189 (35%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPG-GAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
+A+ SL+ L L++VDLYLIH+P G LPA + L L +G+ A+G
Sbjct: 85 RAFDTSLKKLRLDFVDLYLIHWPATGMNLPAAME-----------TLMALKQEGRTRAIG 133
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
V+NFTVA L+ +E V A NQVE+H QS L + K I L AYC +
Sbjct: 134 VANFTVALLKQAVEDIQAPV-ACNQVEYHVMLDQSKLMAYMKSRSIPLVAYCPL-----A 187
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQD-VAVIPKAVHPEHIKEN-RSLNFKIPE 238
D + K AQV L W L QD VA IPKA PE + N ++ ++ +
Sbjct: 188 QGRAAGDETLAGIGRKHGAGAAQVALKWLLDQDGVAAIPKAARPESQQANWDAMKVQLDD 247
Query: 239 EDMKALNQL 247
ED + L
Sbjct: 248 EDRATIAAL 256
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/251 (27%), Positives = 121/251 (48%), Gaps = 21/251 (8%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPS---DHGSRAEQAYQKSLEN 70
LNNG+ MP +GLGT+ ++ + V + + A++AGYR + + +A + +E
Sbjct: 10 LNNGLEMPVLGLGTWLSKEGEGV-EAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAKIEE 68
Query: 71 LDLEYVDLYL----IHFPGGAKLPAEDKRNTKMREL----SWCKLTELYDDGKVNAVGVS 122
+ DL++ I + +P + + ++ +W + +L GKV ++GVS
Sbjct: 69 GVVCREDLFVTTKFIDWDTKNLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVS 128
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
NF + L+ + P NQVE +P Q L +FCK ITL AY G +
Sbjct: 129 NFNSEQITRLLAECE-IKPVTNQVECNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEK 187
Query: 183 S-------LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
L+DP V+ K T QV+L + + IPK+ + E I++N + +F
Sbjct: 188 DPDNMPKPALDDPKVIEIGKKYNKTSGQVILRYLVDIGTIPIPKSSNSERIRQNIDIFDF 247
Query: 235 KIPEEDMKALN 245
K+ EE++K ++
Sbjct: 248 KLTEEEIKIMD 258
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 91.9 bits (218), Expect = 1e-17
Identities = 66/206 (32%), Positives = 102/206 (49%), Gaps = 27/206 (13%)
Query: 66 KSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFT 125
K+L L Y+DL LIH P G + R+ +W L E ++GK+ ++GVSN+
Sbjct: 132 KTLMETGLGYIDLMLIHAPYGGRAA---------RKGAWKALVEAQEEGKIRSLGVSNYG 182
Query: 126 VAHLEGL------MESNHGL----VPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
V HL+ + +E G V V Q E HP+ +S + +C+Q I +AY
Sbjct: 183 VHHLDEMEVYMKELEEERGKGRGGVIDVGQWELHPWLARSDIISWCQQRGIVAEAYSPLI 242
Query: 176 GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NF 234
++ LL P+ K TPAQ+LL W+LQ+ +PK V P IKEN + +F
Sbjct: 243 RGERHDSKLLQ-PLTK----KYNKTPAQILLRWSLQKGFVPLPKTVTPGRIKENADIFDF 297
Query: 235 KIPEEDMKALNQLSEKNVKYAWDPSI 260
++ E+M+ L + WDP++
Sbjct: 298 ELTAEEMEGLE--TGDYYSCTWDPTV 321
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 91.9 bits (218), Expect = 1e-17
Identities = 57/187 (30%), Positives = 102/187 (54%), Gaps = 16/187 (8%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNF 124
++SL L +Y+DL LIH+P + + + M ++ ++G V +GVSNF
Sbjct: 88 RESLNKLGTDYLDLLLIHWPNTPWMASLSETLGAMNDV--------VEEGLVRHIGVSNF 139
Query: 125 TVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSL 184
+ + L+ + + + +QV++HPY+ Q L +C+ H + L AY + + +
Sbjct: 140 SPSLLDRARDISSAPI-FTDQVQYHPYWDQRKLLDYCRIHDVLLTAY-----SPLARGGV 193
Query: 185 LNDPVVVSTALKLEVTPAQVLLVWALQQD-VAVIPKAVHPEHIKENRSL-NFKIPEEDMK 242
L+DP +V K +PAQV L W +QQD VA IPKA EH++ N ++ +F++ + +M+
Sbjct: 194 LDDPALVQIGNKYGKSPAQVALRWLVQQDGVAAIPKASSREHLEANLAVFDFELTDAEME 253
Query: 243 ALNQLSE 249
+ S+
Sbjct: 254 RIRDPSK 260
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 91.5 bits (217), Expect = 2e-17
Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 29/209 (13%)
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTV 126
SL L L+YVDLYLIH P G MR W L EL +GK ++GVSNF
Sbjct: 138 SLARLGLDYVDLYLIHAPYGG----------DMRLEQWRALLELQANGKARSIGVSNFNE 187
Query: 127 AHLEGLMESNHGL-VPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF----------G 175
+HL + + GL +P NQ+E HP+ + L + QH I AY S G
Sbjct: 188 SHLNEIKAA--GLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLVPLSTWRTKEG 245
Query: 176 GTSCSNNSL-LNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-N 233
S + + A K V+ AQ+LL W +Q AV+PK+++P+ +++N L +
Sbjct: 246 QASAKTDEMKAAGTTFRDMAEKYGVSEAQLLLRWGVQNGYAVLPKSMNPDRMRQNIDLFS 305
Query: 234 FKIPEEDMKALNQLSEKNVKYAW---DPS 259
F I + DM + + + + AW DPS
Sbjct: 306 FSIDDTDMAKMATMDQGD-GVAWATGDPS 333
Score = 37.9 bits (84), Expect = 0.26
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
TTF LN +P++G GTY I D + A++AGYR
Sbjct: 38 TTFTLNTTTTIPAVGFGTYLISNDD-AKSTISAAIQAGYR 76
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 91.1 bits (216), Expect = 3e-17
Identities = 61/184 (33%), Positives = 94/184 (51%), Gaps = 18/184 (9%)
Query: 63 AYQKSLENLDLEYVDLYLIHFP------GGAKLPAE--DKRNTKMREL--SWCKLTELYD 112
A++KSL +L L+Y+DLYLIH+P G + + D R E +W +L L+D
Sbjct: 110 AFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHD 169
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G V +G SN T+A L+ L+ + PAVN++E HP++ Q +L+ + + +I YC
Sbjct: 170 RGLVRHIGTSNMTIAKLQLLLRDAR-VRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYC 228
Query: 173 SFGG-------TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEH 225
G + + S L DPV+ A + PA V L WA+Q+ IP + +
Sbjct: 229 PLGSPGRPERDRTAEDTSPLEDPVIQRIAAAHGMHPAAVCLKWAVQRGQTPIPFSTKRRN 288
Query: 226 IKEN 229
I N
Sbjct: 289 IHAN 292
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 91.1 bits (216), Expect = 3e-17
Identities = 62/201 (30%), Positives = 105/201 (52%), Gaps = 17/201 (8%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMR----ELSWCKLTELYD 112
+A +K+L++L L+Y+D YLIH+P G K P + N E +W + +L +
Sbjct: 98 KALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLE 157
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
GKV +G+SNF +LE +++ + PAV+Q+E HP+ Q+ + K+ I + AY
Sbjct: 158 TGKVRHIGLSNFNDTNLERILKVAK-VKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYS 216
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLE------VTPAQVLLVWALQQDVAVIPKAVHPEHI 226
FG + S + + T K+ VT A + + WA+ + +VIPK+V+ + I
Sbjct: 217 PFGNQNTIYESKIPKLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPKSVNEQRI 276
Query: 227 KENRSLNFKIPEEDMKALNQL 247
K N + +EDM +N +
Sbjct: 277 KSNFKY-IPLTKEDMDEINSI 296
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 90.6 bits (215), Expect = 3e-17
Identities = 56/207 (27%), Positives = 104/207 (50%), Gaps = 17/207 (8%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLT 108
+M+ +A A Q SL+ L+L+Y+DLYLIH P A W +
Sbjct: 78 KMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYNDVFGA------------WRAME 125
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
Y G++ A+GVSNF +A L L E + + P +NQ+E +P+ + Q+ + +
Sbjct: 126 SAYRSGQLKAIGVSNFDIAQLTNLAEFSD-IKPMLNQIEVNPFQQNKKDITYFSQYGVQV 184
Query: 169 QAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKE 228
+A+ F N L ++ ++ A K + AQ++L W Q+++ V+ K+V PE + +
Sbjct: 185 EAWAPFAE---GKNDLFSNILLRKIADKHHKSIAQIVLRWLTQRNIIVVAKSVKPERMAQ 241
Query: 229 NRSL-NFKIPEEDMKALNQLSEKNVKY 254
N + +FK+ +++ + L + ++
Sbjct: 242 NLDIFDFKLTHQELAEIETLDTNSSQF 268
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 90.6 bits (215), Expect = 3e-17
Identities = 65/226 (28%), Positives = 107/226 (47%), Gaps = 24/226 (10%)
Query: 47 GYRMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDK--RNTKMREL-- 102
G +++ H E+A SL +L YVDL L+H+P K ED+ R+ + R +
Sbjct: 104 GTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKR-GEDRFPRDAEGRMIHG 162
Query: 103 ------SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSS 156
+W L ++ GKV A+GVSNF+ +E L+ VPAV+Q+E HPY Q
Sbjct: 163 ETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRET-STVPAVHQMEVHPYLQQKG 221
Query: 157 LYKFCKQHHITLQAYCSFGGTS------------CSNNSLLNDPVVVSTALKLEVTPAQV 204
++ ++ I + + G + +++ P++ K +P QV
Sbjct: 222 FNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVIDQPILKEIGQKYGKSPVQV 281
Query: 205 LLVWALQQDVAVIPKAVHPEHIKENRSLNFKIPEEDMKALNQLSEK 250
+L W + +VIPK V I+EN + +F++ EDM + L K
Sbjct: 282 VLAWGINSGRSVIPKTVIDWQIEENLAADFELDAEDMARIATLDAK 327
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 90.6 bits (215), Expect = 3e-17
Identities = 60/204 (29%), Positives = 106/204 (51%), Gaps = 11/204 (5%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHF-----PGGAKLPAEDKRNTKMRELS--WCKLT 108
H R A +++L NL ++YVDL L+H+ PG P + ++ W +
Sbjct: 92 HAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGME 151
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
E + G A+GVSNF+ LE L+ S + PAVNQVE +P + Q +L + C++ + L
Sbjct: 152 ECHRLGLARAIGVSNFSAKKLEQLL-SLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQL 210
Query: 169 QAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
Y G GT + ++++ V+ A T AQ+ L W +Q ++ K + + +
Sbjct: 211 CGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRM 270
Query: 227 KENRSL-NFKIPEEDMKALNQLSE 249
KEN + N+++ +E+ + ++QL +
Sbjct: 271 KENLDIFNWELTDEERERISQLPQ 294
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 90.2 bits (214), Expect = 5e-17
Identities = 60/191 (31%), Positives = 99/191 (51%), Gaps = 21/191 (10%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMREL--SWCKLTELYDDGKVN 117
A + SL+ LEY DLYL+H MR+ +W L + Y++GK+
Sbjct: 95 AAAGIEASLKKSGLEYFDLYLLH--------------QAMRDYFSAWRALEDAYEEGKLK 140
Query: 118 AVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
A+GVSNF L E+ + P VNQVE HPY+ Q K +++ +A+ GG
Sbjct: 141 AIGVSNFYPHVLANFCETVR-VKPMVNQVELHPYFAQPEALATMKYYNVQPEAWAPLGG- 198
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKI 236
+ + ++ S A + + +QV+L W +Q+ V VIPK+ H + I+EN ++ +F +
Sbjct: 199 --GRHKPFENNLLQSIADAHQKSISQVILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSL 256
Query: 237 PEEDMKALNQL 247
E++M ++ L
Sbjct: 257 TEKEMAQISSL 267
Score = 36.3 bits (80), Expect = 0.79
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
VL+N + MP +G G +++ D+ Q V A+ GYR+
Sbjct: 10 VLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRL 47
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 89.8 bits (213), Expect = 6e-17
Identities = 63/196 (32%), Positives = 100/196 (51%), Gaps = 17/196 (8%)
Query: 54 SDHGSR-AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
SDH S A ++SL+NL L+ +DL+LIH+P LP ++ + C+ D
Sbjct: 69 SDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP----LPRHNRYVAAFEAMLACR-----D 119
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G V VGVSNF HL ++ G PAVNQ++ P + + + + ++ Q++
Sbjct: 120 AGLVRHVGVSNFLETHLRRVVAET-GESPAVNQIQMDPSLARLPVRRADDELGVSTQSWS 178
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
G +L PVV A +L+ TPAQV+L W Q V + ++ +P EN +
Sbjct: 179 PLG-----RGEVLGSPVVTDIARRLDRTPAQVVLAWHFAQGVVPVARSANPARQAENLAA 233
Query: 232 LNFKIPEEDMKALNQL 247
L+ ++ D+ ALN+L
Sbjct: 234 LDVRLTAADVDALNRL 249
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 89.8 bits (213), Expect = 6e-17
Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 12/196 (6%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A SLE L L+YVDLYL+H P +P N + +W L + GK ++GVS
Sbjct: 95 ALDASLERLQLDYVDLYLLHNP--YVIP-----NLTDIQSAWKGLEAVKATGKARSIGVS 147
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQS-SLYKFCKQHHITLQAYCSFGGTSCSN 181
NF HLE ++E+ +VPA+NQ+E+HPY +S + ++ I + ++ + +
Sbjct: 148 NFQRNHLEAILET-CSVVPAINQLEYHPYLQRSHDFIPWMRERGIEVSSFKTLAPVTVGK 206
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEED 240
L++P + S A K +T + V+L W + Q++ I E ++E +++ ++ E+
Sbjct: 207 GGPLDEP-LASIAAKHNITTSAVVLNWVISQNIVPITTTTKRERMEEYIAAISLQLDREE 265
Query: 241 MKALNQLSEKNVKYAW 256
+ + Q+ ++ + W
Sbjct: 266 LDEITQIGLRH-HFRW 280
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 89.4 bits (212), Expect = 8e-17
Identities = 67/267 (25%), Positives = 128/267 (47%), Gaps = 29/267 (10%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDL 73
LN+G +P +G G ++I D ++ V+ A+ GYR+ ++ + A ++++N D+
Sbjct: 9 LNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAE-AYNNQTAVGEAIKNSDV 67
Query: 74 EYVDLYL--------IHFPGGAKLPAEDKRNTKMRELSWCKLTELYDD------------ 113
D++L + +K ED + + L + Y D
Sbjct: 68 NRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYGDVAGAWRALEDAQ 127
Query: 114 --GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
GK ++GVSNF L L ++ + P VNQ+E +P++ + K+ ++ + ++A+
Sbjct: 128 KAGKTKSIGVSNFWPDQLMNLQLMSN-VKPVVNQIEVNPWFQREPEVKWNQKDDVAVEAW 186
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
F + + +PV+ K + QV+L W +Q+ + VIPK+VH KEN
Sbjct: 187 APFAE---GKDGIFTNPVLTEIGKKYGKSNGQVILRWLIQRGIIVIPKSVHDARQKENID 243
Query: 232 L-NFKIPEEDMKALNQLSEKNVKYAWD 257
+ +F++ +DM+ + L +KNV +D
Sbjct: 244 IFDFELNNDDMQKIAAL-DKNVSQFFD 269
>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
Ostreococcus|Rep: Aldo/keto reductase family proteins -
Ostreococcus tauri
Length = 336
Score = 89.4 bits (212), Expect = 8e-17
Identities = 63/216 (29%), Positives = 104/216 (48%), Gaps = 12/216 (5%)
Query: 52 APSDHGSRAEQAYQKSLENLDLEYV-DLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
APS+ S E A + N L DL L+H+PG K + +R+ R +W L
Sbjct: 126 APSEMRSEEEAAAAIAGVNERLGRTPDLVLVHWPGRDKESPDSERHRDARRWTWRALENA 185
Query: 111 YDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
G+ A+GVSN+ ++HL L++ + PAVNQ+E H + Q+ L FC+ + +
Sbjct: 186 LKMGQCRAIGVSNYELSHLRELLQF-CDVKPAVNQIELHARFPQTELRAFCESVGVHVVG 244
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
Y G +LL+D V + A + + PA L+ W L +V+ K+ E +EN
Sbjct: 245 YSPLG-----VGALLDDDRVKAYAATIGLRPAPALVRWTLSMGASVVVKSSAAERTEENF 299
Query: 231 SLNFKIPEEDM-----KALNQLSEKNVKYAWDPSIV 261
+ + ++ + K + + VK+ W+PS V
Sbjct: 300 TAISDLDDDFVHEAAEKLETAFASERVKFCWNPSSV 335
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 89.4 bits (212), Expect = 8e-17
Identities = 69/202 (34%), Positives = 103/202 (50%), Gaps = 13/202 (6%)
Query: 53 PSDHGSRA-EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRE-----LSWCK 106
P+ H A E+ + SLE L L+YVDLYL+H P A+ + +++ + +W
Sbjct: 79 PTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSGDGNDRSEIDDEVTPLETWKA 138
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLME-SNHGLV-PAVNQVEWHPYYTQSSLYKFCKQH 164
L E G V ++GVSNF + E LME HG + P VNQVE + Q L KFC +
Sbjct: 139 LEECQRKGLVRSIGVSNF---NEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNRE 195
Query: 165 HITLQAYCSFGGTSCSNNSL-LNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHP 223
I + AY G + L+ + A K +PAQ+ L + ++ IPK+
Sbjct: 196 GILIMAYSPLGKPKPGKKHVFLDSSDLNKMAEKYGRSPAQISLRFLIEIGTIPIPKSSKT 255
Query: 224 EHIKENRS-LNFKIPEEDMKAL 244
+ +KEN L+FK+ E D++AL
Sbjct: 256 DRMKENLDVLSFKLEETDVQAL 277
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/37 (54%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
LNNG +P IGLGTY+I SD V + A+E GYR+
Sbjct: 4 LNNGHSIPPIGLGTYKITGSDGV-AAIKSAVEFGYRL 39
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 89.0 bits (211), Expect = 1e-16
Identities = 67/259 (25%), Positives = 125/259 (48%), Gaps = 26/259 (10%)
Query: 13 VLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLD 72
VLN+G ++P GLG Y+I + + V AL GYR + H + E++ +++ +
Sbjct: 6 VLNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYR-HIDTAHAYQNERSVGRAIHSSG 64
Query: 73 LEYVDLYLIH--FPG---GAKLPAE---DKRNTKMREL------------SWCKLTELYD 112
+ ++++ +P A E + N K +L +W L
Sbjct: 65 IPISEIWITSKLWPSDYDDASQAIERMLELLNLKQIDLLLLHQQVGNYRKAWIALENAVK 124
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
GKV ++G+SNF L L + + P+ QVE HPY+ Q L +F K + ++++
Sbjct: 125 SGKVKSIGISNFDGERLVDLF-NFADIKPSALQVETHPYHQQKELQEFLKPYGTKIESWY 183
Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL 232
G + LL++ + A K T AQ++L W +Q+ + V P++ EH+ EN ++
Sbjct: 184 PLGH---GDQRLLDESRLKKIAQKYNKTVAQIILRWHIQEGIIVFPRSTRVEHLAENINI 240
Query: 233 -NFKIPEEDMKALNQLSEK 250
+F++ ++K + +L +K
Sbjct: 241 FDFELSCTEIKEIRKLDKK 259
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 89.0 bits (211), Expect = 1e-16
Identities = 68/237 (28%), Positives = 120/237 (50%), Gaps = 39/237 (16%)
Query: 49 RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMRELS 103
+++ + ++ E + + SL+NL + Y+DLYL+H+P G A P + N + L+
Sbjct: 84 KLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLN 143
Query: 104 -----WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLY 158
W + L + G V A+GVSNF V ++ L++ +VPAVNQV+ HP++ Q L
Sbjct: 144 RLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAK-IVPAVNQVKLHPFWRQDELV 202
Query: 159 KFCKQHHITLQAYCSFG------GTSCSNNSLLNDP---------------------VVV 191
KFC+ I + A+ G G S S + ++P VV
Sbjct: 203 KFCQSKGIHVSAHTPLGVPASGPGPSDSGSGGEDEPGTPRISFRRSRSVHGPMLKLSVVA 262
Query: 192 STALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQL 247
A + + TP QV+L W LQ+ +V+P ++ + I++N + ++ + +++ LNQ+
Sbjct: 263 EIADRHKKTPEQVILRWGLQRGTSVLPCSLKADRIRKNIDIFSWSLSDDECNCLNQI 319
Score = 34.3 bits (75), Expect = 3.2
Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T F+LN +P+IGLGT++ D+ ++ V AL GYR
Sbjct: 10 TYFLLNTKAKIPAIGLGTWQ-SGGDLCVEAVKRALSEGYR 48
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/191 (29%), Positives = 99/191 (51%), Gaps = 9/191 (4%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A + LE+L LEYVDLYLIHFP +E + E +W L ++G +GVS
Sbjct: 106 ALKADLEDLGLEYVDLYLIHFP----YISEKSHGFDLVE-AWRYLERAKNEGLARNIGVS 160
Query: 123 NFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSS--LYKFCKQHHITLQAYCSFGGTSCS 180
NFT+ +L+ ++++N +P VNQ+E+ Y + + ++ +Q I ++AY G +
Sbjct: 161 NFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQG 220
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEE 239
L D V+ + K + Q+LL W LQ+ + I E I + + +F++ +E
Sbjct: 221 RPGPL-DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKE 279
Query: 240 DMKALNQLSEK 250
D + ++ ++
Sbjct: 280 DEDQITKVGKE 290
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 89.0 bits (211), Expect = 1e-16
Identities = 59/205 (28%), Positives = 103/205 (50%), Gaps = 11/205 (5%)
Query: 56 HGSRAEQAYQKSLENLDLEYVDLYLIHFPGGA-------KLPAEDKRNTKMRELSWCKLT 108
H R A +++L NL ++YVDL L+H+P P E+ E W +
Sbjct: 94 HAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGME 153
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
E + G A+GVSNF+ LE L+ S + PA NQVE +P + Q +L + C++ + L
Sbjct: 154 ECHRLGLARAIGVSNFSAKKLEQLL-SFAVVRPAANQVEMNPMWQQRTLREVCRREGVQL 212
Query: 169 QAYCSFG--GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
Y G GT + ++++ V+ A T AQ+ L W +Q ++ K + +
Sbjct: 213 CGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENRM 272
Query: 227 KENRSL-NFKIPEEDMKALNQLSEK 250
KEN + ++++ EE+ +++L ++
Sbjct: 273 KENLDIFDWELTEEERDKISKLPQQ 297
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 88.2 bits (209), Expect = 2e-16
Identities = 57/189 (30%), Positives = 99/189 (52%), Gaps = 18/189 (9%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
+ + ++SL+ L +YVDL L+H+P AE + + E+ + G+V +G
Sbjct: 85 QASVKESLDKLKTDYVDLLLLHWPVPEVPIAETMK----------AMNEVKEAGQVRHIG 134
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
VSNFTV L+ ++ G NQVE+HPY Q+++ C+ + + AY + +
Sbjct: 135 VSNFTVDLLDEA-RAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAY-----SPIA 188
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQD-VAVIPKAVHPEHIKENRSL-NFKIPE 238
+ +D V+ A V+PAQ++L W + QD V IP++ +HIK N + + K+ +
Sbjct: 189 QGKVFDDEVITEIAKAHNVSPAQIVLRWLIDQDSVIAIPRSSSDKHIKSNFEIADLKLSQ 248
Query: 239 EDMKALNQL 247
E+ +N L
Sbjct: 249 EETGRINSL 257
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 88.2 bits (209), Expect = 2e-16
Identities = 58/195 (29%), Positives = 98/195 (50%), Gaps = 16/195 (8%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R E + SL L +Y+DL LIH+P + P+ + LS +L + D G
Sbjct: 88 RFETSVIDSLTALQTKYLDLLLIHWPLNSDEPS------MVEYLS--ELKAVLDKGLTRR 139
Query: 119 VGVSNFTVAHL-EGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
+GVSNFT A L + + G++ NQVE HPY + FC+QH++ + Y F
Sbjct: 140 IGVSNFTNAQLAQAIAILGEGVI-YTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPF--- 195
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKI 236
+ ++L D +V+ A + TPAQ++L W Q A IP + ++++ N + + +
Sbjct: 196 --AYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRDNVRSNLAAASINL 253
Query: 237 PEEDMKALNQLSEKN 251
+++ +NQL +
Sbjct: 254 TPAEIEQINQLDRNH 268
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 88.2 bits (209), Expect = 2e-16
Identities = 57/197 (28%), Positives = 102/197 (51%), Gaps = 14/197 (7%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRN-TKMREL--------SWCKLTELY 111
E+ + +L+ L ++YVDLYL+H P + + RN TK+ + +W L + Y
Sbjct: 95 EKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCY 154
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
+G ++GVSNF + L+ S+ +VPAVNQ+E + Q + KFC+Q +I + Y
Sbjct: 155 QEGLCRSIGVSNFNEHQINALL-SDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMGY 213
Query: 172 CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRS 231
G L + + AL ++ T AQV L + + + V I K+ + +EN
Sbjct: 214 TPLGKQKL---PFLQNNRLKEIALSVDKTTAQVSLRYLIDEGVVPIVKSTDRKRQQENLD 270
Query: 232 L-NFKIPEEDMKALNQL 247
+ +FK+ ++ ++ L+ +
Sbjct: 271 IFDFKLTKQQLEELDAI 287
Score = 34.3 bits (75), Expect = 3.2
Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 16 NGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
+ I +P+IGLGTY I +D + + A++ GYRMF
Sbjct: 13 HSIALPTIGLGTYSILGAD-GKEAIRTAIDVGYRMF 47
>UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 274
Score = 88.2 bits (209), Expect = 2e-16
Identities = 64/249 (25%), Positives = 120/249 (48%), Gaps = 12/249 (4%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAY----QK 66
TF LN G +P+IGLGT++ + + + A R P S +
Sbjct: 10 TFQLNTGKTIPAIGLGTWQSQPGEGDRRGASAASGRAARGDLPDQPSSTTPGTSGPLKRS 69
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAED-KRNTKMREL--SWCKLTELYDDGKVNAVGVSN 123
S + ++ G + ED K++ + +W ++ +L D K+ +GVSN
Sbjct: 70 SARSKTWAWITSTYTSCTGPSSTTPEDLKKHYPDWDFVDTWREMQKLMDTNKIRNLGVSN 129
Query: 124 FTVAHLEGLM-ESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNN 182
F + +LE L+ + + +VPAVNQ+E HP L +C + I Y G S++
Sbjct: 130 FGIKNLERLLNDPSCKIVPAVNQIELHPGNPSPKLIAYCAEKGIHCSGYSPLGS---SDS 186
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSLN-FKIPEEDM 241
L + + S A + QVLL+W +++ +V+PK+V+P+ +K N L+ + + +E++
Sbjct: 187 PLYKNETIASIAKAKNRSVQQVLLMWGVKKGWSVLPKSVNPDRVKANFDLDGWDLTDEEV 246
Query: 242 KALNQLSEK 250
++ + ++
Sbjct: 247 AKIDSIPDR 255
>UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 276
Score = 87.8 bits (208), Expect = 2e-16
Identities = 64/205 (31%), Positives = 104/205 (50%), Gaps = 18/205 (8%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R +A ++SL +D+ LIH P K P R SW L + +G++N
Sbjct: 87 RTWKAVEQSLRRTGRPKLDVVLIHSP---KWPVR-------RIESWRALLQHQKEGRINK 136
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSN+ + HLE ++ L PA+NQVE+ + + + +C H I +QA+ +
Sbjct: 137 IGVSNYNIHHLEEIISLGLPL-PAINQVEFSAFNNRPTFLSYCFNHGILVQAF-----SP 190
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIP 237
+ L+D ++ +LK TPA +LL + LQ+ V+ I KA HI EN ++ F +
Sbjct: 191 LTRGYRLSDIRLLDLSLKYNKTPANILLRYCLQKGVSPIFKASSFVHIHENVKAEQFMLD 250
Query: 238 EEDMKALNQLSEKNV-KYAWDPSIV 261
DM ++ E+ V K W+P I+
Sbjct: 251 PSDMDVMDTWDEEFVSKPTWNPIIL 275
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 87.0 bits (206), Expect = 4e-16
Identities = 56/181 (30%), Positives = 83/181 (45%), Gaps = 6/181 (3%)
Query: 54 SDHGSR-AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
+DH +A + S+ NL +EY+DLYLIH+P D N +W + EL
Sbjct: 125 TDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVR 184
Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G +G SNF + +++ + P ++ E HPY Q S F K+ +I + A
Sbjct: 185 AGLTRNIGFSNFAPKDINKILKI-ASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAAS 243
Query: 173 SFGGTSCSNN----SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKE 228
T+ + S+L+D V A T AQ +L W Q+ VI K+ H HI E
Sbjct: 244 PLANTNPTYGDKYPSILHDEFWVKLAEDKNATVAQTILAWGQQRGTIVISKSTHSNHIAE 303
Query: 229 N 229
N
Sbjct: 304 N 304
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 87.0 bits (206), Expect = 4e-16
Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 17/205 (8%)
Query: 56 HGSRAEQ-AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDG 114
HG + Q ++Q+SL L L+Y+D ++H+P K + S+ L ++ G
Sbjct: 93 HGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK---------GLYVESFAALAKIQGLG 143
Query: 115 KVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
++ +V V+NF L ++ G+ P +NQVE HP ++Q+ ++ + +A+
Sbjct: 144 QLQSVAVANFYPEVLREIVAET-GIAPVLNQVELHPGFSQAEQRAVDRELGVVTEAWSPL 202
Query: 175 GGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-N 233
G LN + A E TPAQV L W Q +V+PK+ +P+ +EN + +
Sbjct: 203 G-----RGDSLNAEAITLIAQCYEKTPAQVTLRWIHQLGCSVVPKSANPQRQRENLDIFD 257
Query: 234 FKIPEEDMKALNQLSEKNVKYAWDP 258
F++ EDM ++ L E+ + DP
Sbjct: 258 FELNTEDMNSITSLDEQGGRLFVDP 282
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 1 MASSDPIIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
M + IIPT LN+G MP+IG GTY++R+ D + V A+E GYR
Sbjct: 4 MKQHENIIPT-ITLNDGTEMPAIGFGTYKLREQD-AYRAVRSAIEVGYR 50
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 86.6 bits (205), Expect = 6e-16
Identities = 66/200 (33%), Positives = 99/200 (49%), Gaps = 21/200 (10%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVS 122
A ++SL+ L +YVDL++IH P K P ++ + EL D ++ +
Sbjct: 101 ALERSLKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELI--- 157
Query: 123 NFTVAHLEGLMESNHGLVPAVNQV-EWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSN 181
+ GL P NQV E HPY QS L +FCK I L AY + G
Sbjct: 158 ----LNKPGLRYK-----PTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQ 208
Query: 182 ------NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNF 234
LL +P++ S A K +P QV L + LQ+ V V+ K+ E IKEN + +F
Sbjct: 209 WVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDF 268
Query: 235 KIPEEDMKALNQLSEKNVKY 254
++ EDMKA++ L+ +N++Y
Sbjct: 269 ELTPEDMKAIDGLN-RNLRY 287
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 85.8 bits (203), Expect = 1e-15
Identities = 57/198 (28%), Positives = 98/198 (49%), Gaps = 17/198 (8%)
Query: 60 AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAV 119
A+++ +KSL+ L L+Y+D LIH P ++ K + E Y G + +
Sbjct: 86 AKKSIEKSLKTLGLDYIDSLLIHMPY-----SQSKAMYRAME-------SFYKQGILRVI 133
Query: 120 GVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
G+SNF ++S ++PA+NQ E H Q L + K LQ++ F
Sbjct: 134 GISNFGAKAYSEFVKSCE-VIPAINQCETHLLLQQKPLREAMKSKKTLLQSWSPF---IA 189
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPE 238
S+L +P + S A K TPAQV+L + ++Q ++VIPK ++EN ++ +F +
Sbjct: 190 GKGSILENPTLKSIAQKYNKTPAQVVLRFLIEQGISVIPKTSKRARMQENLNVFDFSLSA 249
Query: 239 EDMKALNQLSEKNVKYAW 256
+D + L +L ++W
Sbjct: 250 QDTQILKELDTNKSAFSW 267
Score = 40.3 bits (90), Expect = 0.048
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
T LNNG+ MP +GLGTY + + + A+E GYR+F
Sbjct: 3 TLTLNNGVKMPILGLGTYSL-TGKAGQKAMSEAIEVGYRLF 42
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 85.8 bits (203), Expect = 1e-15
Identities = 57/204 (27%), Positives = 105/204 (51%), Gaps = 17/204 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVN 117
++A + ++SL+ + +E +DL LIH+P +P++D + +W ++ D+G +
Sbjct: 85 AKARASVERSLKTIGVEQLDLVLIHWP----VPSQD-----LYLETWKAFQDMRDEGLMR 135
Query: 118 AVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
++G SNF HLE ++ + G P +NQ+E +P Q + K H + QA+ G
Sbjct: 136 SIGTSNFNADHLERII-AETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNA 194
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKI 236
S +P+ + A + +P QV+L W +Q AVIP++V EN + +F +
Sbjct: 195 ----RSFEAEPITKAVA-RTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAENLDVFDFTL 249
Query: 237 PEEDMKALNQLSEKNVKYAWDPSI 260
E +M + L + ++ DPS+
Sbjct: 250 TEAEMSEIATL-DMGLRTGPDPSV 272
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/199 (26%), Positives = 100/199 (50%), Gaps = 17/199 (8%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
++A+ +S + L ++YVDLYL+H+P P D ++ + E+ G ++G
Sbjct: 94 KEAFAESQKKLGMDYVDLYLLHWP----CPQADSFVQ-----AYDSMAEIQQSGGATSIG 144
Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
V NF L+ L ++ H PAVNQ+E HP ++Q+ + I +A+ G
Sbjct: 145 VCNFYPEALDALKQAGH--TPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSPLG----- 197
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEE 239
L DP + A + V+ AQ ++ W +Q+ VIP++ E +++N + F++ +
Sbjct: 198 QGQNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIPRSSKVERVRQNFDVFGFELSAD 257
Query: 240 DMKALNQLSEKNVKYAWDP 258
++ A+ L ++ + DP
Sbjct: 258 EVSAIEALDVEDGRIGGDP 276
>UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides ovatus ATCC 8483
Length = 279
Score = 85.4 bits (202), Expect = 1e-15
Identities = 63/198 (31%), Positives = 101/198 (51%), Gaps = 21/198 (10%)
Query: 53 PSDHGSRAEQ-AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
PS+ R + A ++SL L EY+DLYL+H+ G + P E+ +TEL
Sbjct: 83 PSNASYRGTKLACERSLLKLGTEYIDLYLLHWKG--RHPYEETVRA---------MTELQ 131
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWH--PYYTQSSLYKFCKQHHITLQ 169
+GK+ GVSN A +E ++ + G A +QV ++ + L +C + L
Sbjct: 132 QEGKIRLWGVSNMDTADMERIVSLSGGSGCATDQVLYNLGDRGIEFDLMPWCAARRMPLM 191
Query: 170 AYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQ-DVAVIPKAVHPEHIKE 228
AY G LL P +V A + +V+PAQ+ L W ++Q + IPKA + H+++
Sbjct: 192 AYSPIG-----EGRLLRHPTLVEIARRHDVSPAQIALSWTMRQPGIIAIPKAGNVTHVED 246
Query: 229 N-RSLNFKIPEEDMKALN 245
N RSL+ + EED+ L+
Sbjct: 247 NFRSLSIHLTEEDLHDLD 264
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 85.4 bits (202), Expect = 1e-15
Identities = 62/216 (28%), Positives = 112/216 (51%), Gaps = 20/216 (9%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFP--------GGAKLPAEDKRNTKMREL-----SWCKL 107
E+A +K+L++L L+Y+DLYL+H+P GG+ P ++K NT + +W +
Sbjct: 82 EEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNTIFDDGVSLIDTWKAM 141
Query: 108 TELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHIT 167
+L + G V +GVSN+T+ LE L S+ P NQVE++ Y Q L ++ + I
Sbjct: 142 EKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGII 201
Query: 168 LQAYCSFGGTSCSNNS---LLNDPVVVSTALKLEVTPAQVLLVWAL--QQDVAVIPKAVH 222
+ Y + G + +L D + A + + +V L + L + +++ K+V
Sbjct: 202 VTGYSTLGTPDWAKPDEPVVLKDEELNKIAAETGKSVGEVELKFLLTIEPGASLLAKSVT 261
Query: 223 PEHIKENRSLNFKIPEEDMKALNQLSEKNVKYAWDP 258
PE I +N L+F++ ++ ++ L E+ +Y DP
Sbjct: 262 PERIYKNNHLDFELTKDQIQRLRN-RERFYRYV-DP 295
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/187 (28%), Positives = 99/187 (52%), Gaps = 12/187 (6%)
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTV 126
+L+ + +YVDLYL+H P +K + N E +W + +LY GK +GVSNF V
Sbjct: 107 ALKKMGTDYVDLYLLHSPFVSK-----EVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAV 161
Query: 127 AHLEGLMESNHGLVPAVNQVEWHPYYTQSS--LYKFCKQHHITLQAYCSFG---GTSCSN 181
L+ +++ + P VNQ+E+ P+ + +YKFC++H I ++AY G + +
Sbjct: 162 EDLQRILKVAE-VKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQD 220
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEED 240
+S V + K + AQ++L W ++ V + + P+ I + ++L +F + E+
Sbjct: 221 DSQPFFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEE 280
Query: 241 MKALNQL 247
+ + +L
Sbjct: 281 VDKITEL 287
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 85.0 bits (201), Expect = 2e-15
Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 12/200 (6%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKR---NTKMRELSWCKLTELYDDGK 115
+ ++ Q SL+ L Y+DLYLI + L D N + W +L E + G
Sbjct: 103 KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGM 162
Query: 116 VNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFG 175
+ ++GV+NF + L+ S + P VNQ+E PY Q L F K+ I A G
Sbjct: 163 IRSIGVANFNCQMVLDLL-SYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPLG 221
Query: 176 GTSCSNNS-------LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKE 228
C N+ LL + + A K + + QV+L +Q+++ +IPK + +KE
Sbjct: 222 RAGCFENTPEGMKIKLLEEDIFKQIAQKHKKSVVQVILRCLVQREIMMIPKTAKLDRLKE 281
Query: 229 NRSL-NFKIPEEDMKALNQL 247
N + +F++ EEDMK + L
Sbjct: 282 NSEIFDFELTEEDMKQIYSL 301
>UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG05425 - Caenorhabditis
briggsae
Length = 319
Score = 85.0 bits (201), Expect = 2e-15
Identities = 58/192 (30%), Positives = 96/192 (50%), Gaps = 27/192 (14%)
Query: 57 GSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKV 116
G ++ ++SL+ L+ EY+DL L+H+P +D+RN R+ +W L L
Sbjct: 139 GELIKKDIEESLKLLNREYLDLVLVHYPRPFTTDDKDERNKIYRKEAWLALESLK----- 193
Query: 117 NAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG 176
S FT P VNQVE+HP++ + L +FC+++ I QA+ FG
Sbjct: 194 -----SLFTXE-------------PTVNQVEFHPHFQRKELREFCQKNGILFQAFSPFGR 235
Query: 177 TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFK 235
N++LLND ++ A K T + V+L W +Q V K+ E + EN +S +
Sbjct: 236 ---GNSALLNDQIMTGIAEKHHTTVSSVILTWIVQSGNGVAVKSKSIERVSENFKSTTLQ 292
Query: 236 IPEEDMKALNQL 247
+ +E+M + +L
Sbjct: 293 LTDEEMVKIKEL 304
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 85.0 bits (201), Expect = 2e-15
Identities = 56/192 (29%), Positives = 98/192 (51%), Gaps = 21/192 (10%)
Query: 59 RAEQAYQKSLENLD-LEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVN 117
RA+ A ++ L + L+Y+DL LIH P +K+R +W + E D+G V
Sbjct: 91 RAKAAIRQCLNEVSGLQYIDLLLIHSP---------LEGSKLRLETWRAMQEAVDEGLVK 141
Query: 118 AVGVSNFTVAHLEGLM---ESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSF 174
++GVSN+ H++ L+ E H P VNQ+E P+ + L +CK + ++A+
Sbjct: 142 SIGVSNYGKKHIDELLNWPELKH--KPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPL 199
Query: 175 GGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLN 233
C + N P ++ +++ P QVL+ W+LQ +PK + ++ N + N
Sbjct: 200 ----CHGYKMTN-PDLLKVCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYN 254
Query: 234 FKIPEEDMKALN 245
F++ +E MK L+
Sbjct: 255 FELSDEQMKFLD 266
Score = 37.9 bits (84), Expect = 0.26
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 7 IIPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
++P + L+NG +PSI LGTY I +S ++V ++ GYR F
Sbjct: 1 MVPKFYKLSNGFKIPSIALGTYDIPRSQ-TAEIVYEGVKCGYRHF 44
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 18/202 (8%)
Query: 63 AYQKSLENLDLEYVDLYLIHFPGGAK-------LPAEDKRNTKMREL--SWCKLTELYDD 113
A ++SL+ L L Y+DLYL+H+P LP + + +W + E
Sbjct: 97 ACKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKL 156
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCS 173
G ++GVSNF L L+ES + P +NQ+E H Q L +FC I + Y
Sbjct: 157 GLTRSIGVSNFNSQQLTRLLESA-SIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSP 215
Query: 174 FGGTSCSN-------NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHI 226
FG +N + L PV+ A K T AQ++L + + IPK+ + I
Sbjct: 216 FGAPGRNNVFQPAGADISLQSPVITGIAKKYNKTNAQIVLRYVIDIGAIPIPKSSSEKRI 275
Query: 227 KENRSL-NFKIPEEDMKALNQL 247
KEN + +FK+ E++ A+++L
Sbjct: 276 KENIDIFDFKLTPEEIAAIDKL 297
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 84.6 bits (200), Expect = 2e-15
Identities = 47/120 (39%), Positives = 69/120 (57%), Gaps = 6/120 (5%)
Query: 54 SDHGSR-AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMREL----SWCKLT 108
+DH + +A ++L++L LEYVDLYLIH+P K + + + + +W +
Sbjct: 85 TDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAME 144
Query: 109 ELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITL 168
LYD GK A+GVSNF+ L L+E + PAVNQVE HP + Q+ L +FCK + L
Sbjct: 145 ALYDSGKARAIGVSNFSTKKLADLLELAR-VPPAVNQVECHPSWRQTKLQEFCKSKGVHL 203
Score = 32.7 bits (71), Expect = 9.7
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 10 TTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
T F LN G PS+GLGT++ +V V A++ GYR
Sbjct: 6 TFFKLNTGAKFPSVGLGTWQ-ASPGLVGDAVAAAVKIGYR 44
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 84.6 bits (200), Expect = 2e-15
Identities = 58/195 (29%), Positives = 102/195 (52%), Gaps = 20/195 (10%)
Query: 55 DHGSRA-EQAYQKSLENLD-LEYVDLYLIHFPGGAKLPAEDKRNTKMREL-SWCKLTELY 111
+HG A +++ +KSL L Y+DL L+H P + + R L +W L E
Sbjct: 92 NHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP----------MSDRTRRLGTWQALEEAV 141
Query: 112 DDGKVNAVGVSNFTVAHLEGLME-SNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQA 170
+G+V ++GVSN+ HL L+ + P VNQVE +P+ + L ++C++++I +QA
Sbjct: 142 VEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYCRENNIAVQA 201
Query: 171 YCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENR 230
+ + L+DP++ A + + AQ+L+ W++Q V+PKA E + N
Sbjct: 202 F-----SPLMRGKRLDDPILQKVAHQYDKGVAQILVRWSIQMGFIVLPKAAKKERLAPNF 256
Query: 231 SL-NFKIPEEDMKAL 244
+ +F++ E M L
Sbjct: 257 DIWDFELSAETMSEL 271
Score = 38.3 bits (85), Expect = 0.20
Identities = 17/38 (44%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMF 51
L++G +PS+GLG Y++ + V +V ALE GYR+F
Sbjct: 15 LSDGTQIPSVGLGVYQVSE-QTVQDLVYEALEVGYRLF 51
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 83.8 bits (198), Expect = 4e-15
Identities = 57/202 (28%), Positives = 101/202 (50%), Gaps = 17/202 (8%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R ++ +SL+ LD Y+DL L+H P G A + L LY + KV
Sbjct: 86 RCYESVIESLKRLDTSYLDLILLHQPFGNYYKA------------YQDLERLYKENKVRN 133
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+GVSNF + L N + P VNQ+E +P++ + + ++ + QA+ F
Sbjct: 134 IGVSNFWDNRIIDLCFFNQ-IKPMVNQIEINPFHQRIEDRFYNDKYKVVSQAWAPFAE-- 190
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
N L +P +V K TPAQV+L W +Q +V + K V+ +KEN + +F++
Sbjct: 191 -GKNGLFTNPTLVEIGKKYNKTPAQVILRWLVQSNVVALCKTVNESRMKENFDIFDFELS 249
Query: 238 EEDMKALNQLSEKNVKYAWDPS 259
++D+ + L++++ ++ + S
Sbjct: 250 KQDLDKIVALNKQHSEFRYHHS 271
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 83.8 bits (198), Expect = 4e-15
Identities = 64/200 (32%), Positives = 99/200 (49%), Gaps = 23/200 (11%)
Query: 51 FAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTEL 110
FAP+D E++ ++SL L L VDL L+H+P + +P + L+
Sbjct: 78 FAPND----LERSVKESLARLRLPSVDLLLLHWPN-SHVPLAETLGA---------LSHA 123
Query: 111 YDDGKVNAVGVSNFTVAHLEGLME-SNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQ 169
G +GVSNFTVA +E + S LV NQVE+HPY Q+ + C QH + L
Sbjct: 124 RQMGLTRHIGVSNFTVALIEQAVALSPEPLV--CNQVEFHPYLDQAKVRAACDQHGLALV 181
Query: 170 AYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN 229
AY + + + D + TPAQV L W +QQ+VA IP+ E + EN
Sbjct: 182 AY-----SPIARGRIKTDQTLAGIGRAHRKTPAQVCLRWLVQQNVAAIPRTSRIERLSEN 236
Query: 230 RSL-NFKIPEEDMKALNQLS 248
+ +F++ +++M + L+
Sbjct: 237 IEIFDFELSDDEMARIAALA 256
Score = 32.7 bits (71), Expect = 9.7
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 12 FVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
FV NG +P+IGLGT+ + +VV+ AL GYR
Sbjct: 3 FVEANGARIPAIGLGTWELSGRPCA-RVVEQALRLGYR 39
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 83.8 bits (198), Expect = 4e-15
Identities = 58/202 (28%), Positives = 104/202 (51%), Gaps = 19/202 (9%)
Query: 61 EQAYQKSLENLDLEYVDLYLIHFPGGAKL---------PAEDKRNTKMREL----SWCKL 107
E+A+++S + LD+ Y+DL+L+H P G + P + N ++ +W +
Sbjct: 93 EEAFRRSFDMLDIGYIDLFLMHSPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAM 152
Query: 108 TELYD-DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHI 166
+L G+V ++G+SNF +E +++ + P NQVE +P Y Q L FC+ I
Sbjct: 153 EKLVTAGGRVRSIGLSNFNSEQIERILQI-ATVKPVNNQVEANPGYDQRKLIAFCQARGI 211
Query: 167 TLQAYCSFG---GTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHP 223
T+ AY G T+ N + L+DP V+ K T QV+L + + IP + +
Sbjct: 212 TVTAYGPMGRPHRTTNGNRNALDDPKVLEIGRKYGKTGGQVILRYLIDIGTIPIPYSTNE 271
Query: 224 EHIKENRSL-NFKIPEEDMKAL 244
E +++N + +FK+ E+++ L
Sbjct: 272 ERMRQNIDVCDFKLTGEEIEYL 293
>UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Eukaryota|Rep: Oxidoreductase, aldo/keto
reductase family protein - Trichomonas vaginalis G3
Length = 286
Score = 83.8 bits (198), Expect = 4e-15
Identities = 59/199 (29%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 53 PSDHGSR-AEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
PS+ G + + +KSL++L +EY+DLYL+H+ G ++P ++E C + EL
Sbjct: 85 PSNAGRKNIFNSCEKSLQHLGIEYLDLYLLHWRG--RVP--------LKETVEC-MEELV 133
Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWH--PYYTQSSLYKFCKQHHITLQ 169
GK+ GVSNF V ++ L +G VNQV +H + L + + H++ L
Sbjct: 134 KQGKIKQWGVSNFDVDDMKELWSIPNGDHCVVNQVLYHLGSRGIEYELIPWMRSHNVKLM 193
Query: 170 AYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAV-IPKAVHPEHIKE 228
AYC L + V+ A K + Q+LL + L D+ IPK+ PEH +
Sbjct: 194 AYCPIAQAGDLKRQLFTNKVLKRIAAKHNCSIVQILLRFVLNCDICTPIPKSAKPEHAAD 253
Query: 229 N-RSLNFKIPEEDMKALNQ 246
N +++N ++ +E+ +++
Sbjct: 254 NLKAINLQLTDEEWAEIDK 272
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 83.8 bits (198), Expect = 4e-15
Identities = 53/191 (27%), Positives = 97/191 (50%), Gaps = 15/191 (7%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNF 124
++SL+ L +YVDLY +H+P P+ + T + +L D+G++ +G+SNF
Sbjct: 93 EESLKKLGTDYVDLYQLHWPN----PSVSIKETMSA------MEKLVDEGRIRYIGISNF 142
Query: 125 TVAHLEGLMESNHGLVPAVNQVEWHPYYTQ---SSLYKFCKQHHITLQAYCSFGGTSCSN 181
+V ++ M + NQ+E++ + +Y FC+++ + + AY
Sbjct: 143 SVKEMKEAMSALAKYRIVSNQLEYNVATREIEDEGIYDFCRKNGMAIIAYSPLSHGKIFG 202
Query: 182 NSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEED 240
N ++ + + K PAQV L W +++ IPKA P H+ EN S +F + +ED
Sbjct: 203 NEMILE-TLTDIGKKYGKRPAQVALNWIIRKGAFPIPKASKPIHMAENIESTDFTLSDED 261
Query: 241 MKALNQLSEKN 251
MK L+ L +++
Sbjct: 262 MKTLDSLYQRH 272
>UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 246
Score = 83.4 bits (197), Expect = 5e-15
Identities = 57/190 (30%), Positives = 95/190 (50%), Gaps = 20/190 (10%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
++ + SL L +Y+DL+LIH G +E SW + EL+ GK+ ++GV
Sbjct: 75 KSVEMSLRALSTDYIDLFLIHSKTGT-----------WKE-SWKAMEELHRQGKIRSLGV 122
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEW-HPYYTQSSLYKFCKQHHITLQAYCSFGGTSCS 180
SNF V L+ L+ N VP W P++ +FC +H I Y + G T
Sbjct: 123 SNFNVDELQELV--NFATVPVSAVQNWFDPFHQDRKARRFCNKHGIRYIGYSTLGKT--- 177
Query: 181 NNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEE 239
N +L V + E +QV+L WA+ Q+V VIP++ + +I N RSL+ + E
Sbjct: 178 -NPVLQSKVFSEISSHYEYVISQVVLRWAIHQNVTVIPRSRNSRNIYLNFRSLDLSLNEN 236
Query: 240 DMKALNQLSE 249
+++ + +++
Sbjct: 237 EIEMITNVTD 246
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 83.4 bits (197), Expect = 5e-15
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 21/213 (9%)
Query: 47 GYRMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCK 106
G+R F G + ++L+ L+ +YVDL+LIH P E + E +W +
Sbjct: 102 GFRTFPAISSGPT--EFIDRALKELETDYVDLFLIHSP----FFEEKVSRGQTLESAWAE 155
Query: 107 LTELYDDGKVNAVGVSNFTVAHLEGLME--SNHGLVPAVNQVEWHPYYTQSS--LYKFCK 162
+ + GKV +GVSNF+ HLE + N P VNQ+E+HPY S + KF +
Sbjct: 156 VIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSPGIIKFAQ 215
Query: 163 QHHITLQAY--------CSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDV 214
++ I ++AY G ++ L ++ A K T AQ+LL + LQ+ +
Sbjct: 216 ENDILIEAYGPLSTLFRIKQNGVDVEDHPL--KELIPKLAEKYGKTDAQILLRYTLQKKI 273
Query: 215 AVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQ 246
I + + I+++ + NF+I +ED+ +++
Sbjct: 274 LPITTSSKLDRIRQSLEVYNFEISDEDVAEIDK 306
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 82.6 bits (195), Expect = 9e-15
Identities = 68/219 (31%), Positives = 110/219 (50%), Gaps = 27/219 (12%)
Query: 57 GSRAE--QAYQK-SLENLDLEYVDLYLIHFPGGA---KLPAEDKRN--------TKMREL 102
G RAE ++Y K SLE L LEYV++YLIH P K E N T +
Sbjct: 105 GMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHV 164
Query: 103 S-WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFC 161
+ W + + G+V ++G+SNF + L + E + P+ Q+E Y Q + + C
Sbjct: 165 AIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE-IKPSNLQIELQAYNQQRPMRELC 223
Query: 162 KQHHITLQAYCSFGGTSCSNN----------SLLNDPVVVSTALKLEVTPAQVLLVWALQ 211
+ +IT+ A+ + G S + +L + P+V A T AQVLL A+Q
Sbjct: 224 AERNITVTAFSTLGSPGSSPDKKTRYIKSLPTLFDHPIVKKIAEAHNRTSAQVLLRHAVQ 283
Query: 212 QDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
+ V+PK+ +P IK+N + +F + E++M+A+N L +
Sbjct: 284 NGIIVLPKSTNPGRIKQNIGIFDFALTEDEMQAMNGLDK 322
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 82.6 bits (195), Expect = 9e-15
Identities = 66/238 (27%), Positives = 113/238 (47%), Gaps = 31/238 (13%)
Query: 30 IRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKL 89
IR S + + + FA D +++ +KSLE L ++ VDL L+H+P
Sbjct: 61 IRNSGVKRDEIFLTTKVWIDQFADGD----LQRSAEKSLEKLGVDQVDLLLLHWPKPEVP 116
Query: 90 PAED-KRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEW 148
AE K +R W + A+G+SNF A LE + + + A +QVE+
Sbjct: 117 LAETLKALNAVRAKGWTR-----------AIGLSNFPSAQLEEAAKLSEAPI-ATDQVEY 164
Query: 149 HPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVW 208
HPY + +L Q +++ A+ + + + DPV++ TP QV L W
Sbjct: 165 HPYLSLKTLKAKADQLGVSITAW-----SPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRW 219
Query: 209 ALQQDVAVIPKAVHPEHIKENRS-LNFKIPEEDMKALNQLSEKNVK--------YAWD 257
+QQ + IP+ +P+ I+EN L+F++ E++M ++ L+ + + YAWD
Sbjct: 220 IIQQGIIAIPRTSNPKRIEENFDILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWD 277
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 82.6 bits (195), Expect = 9e-15
Identities = 60/222 (27%), Positives = 113/222 (50%), Gaps = 29/222 (13%)
Query: 65 QKSLENLDLEYVDLYLIHFP-------GGAKLPAEDKRNTKMREL----SWCKLTELYDD 113
+K++ +L ++Y+DL+L+H+P G P + + + ++ +W + +L ++
Sbjct: 87 KKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRAMEQLVEE 146
Query: 114 GKVNAVGVSNFTVAHLEGLMESNHGLV-PAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G V +GVSN+TV L L+ N+ + P VNQ+E HP++ + KFC + I + AY
Sbjct: 147 GLVKHIGVSNYTVPLLADLL--NYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYS 204
Query: 173 SFGG--------TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQ----DVAVIPKA 220
GG + N +L + + A +P V L W +++ +VIPK+
Sbjct: 205 PMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCVALAWHVKKWNTSMYSVIPKS 264
Query: 221 VHPEHIKEN-RSLNFKIPEEDMKALNQLS-EKNVKYAWDPSI 260
P I+ N + ++ ++DM A+N + K +++ DP+I
Sbjct: 265 QTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIRFC-DPAI 305
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 82.6 bits (195), Expect = 9e-15
Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 17/197 (8%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAK-------LPAED--KRNTKMREL--SWCKLTELYDD 113
+K+L+ L LEY+DL L+H+ + LP ++ K T+ ++ +W + E Y+
Sbjct: 87 KKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKIITENIDILETWKAMEECYNL 146
Query: 114 GKVNAVGVSNFTVAHLEGLM-ESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
G +GVSNF++ LE + + + P NQVE H Y Q + + Q + + +Y
Sbjct: 147 GLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMISYT 206
Query: 173 SFGGTSCSNN---SLLNDPVVVSTALKLEVTPAQVLLVWALQQD--VAVIPKAVHPEHIK 227
G + LL DPV+ A ++ TPAQ L + L+ VIPK+++P +IK
Sbjct: 207 CLGRATLKGPYGYPLLQDPVLNEVAKEIGKTPAQTNLRFLLKLSPYAVVIPKSLNPANIK 266
Query: 228 ENRSLNFKIPEEDMKAL 244
N SL+F + +E + L
Sbjct: 267 GNISLDFDLTQEQFEKL 283
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 81.4 bits (192), Expect = 2e-14
Identities = 53/185 (28%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
Query: 65 QKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNF 124
++ L+ L ++YVDL LIH P A + N K W + E++ G +GVSNF
Sbjct: 98 KEQLQKLQVDYVDLLLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNF 157
Query: 125 TVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSL 184
+ L+ + + P VNQ+E H + Q +L +F K+ +I A+ N +
Sbjct: 158 NCQMIIDLL-AYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAF----SPMAKYNEV 212
Query: 185 LNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMKA 243
+ + + A K + AQV++ + QDV VIP+ E ++ N + + EED++
Sbjct: 213 VKNETLNQIAQKQNASVAQVMIAFMYHQDVVVIPRTAKIERLQHNFDAQKLQFSEEDIQT 272
Query: 244 LNQLS 248
L L+
Sbjct: 273 LRNLN 277
Score = 36.3 bits (80), Expect = 0.79
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 8 IPTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
I L+NG MP+ GLG+ R++ + V ++ AL+ GYR
Sbjct: 6 IQKVITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYR 47
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 81.0 bits (191), Expect = 3e-14
Identities = 52/186 (27%), Positives = 101/186 (54%), Gaps = 11/186 (5%)
Query: 68 LENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTVA 127
L+ L L+YVDLYLIH P E K + + ++ W + LY +GK ++GVSNF+V
Sbjct: 108 LKTLGLDYVDLYLIHSPF---FDPEFKGSLTLEKV-WKDMETLYKEGKAKSIGVSNFSVK 163
Query: 128 HLEGLMESNHGLVPAVNQVEWHPYYTQSS--LYKFCKQHHITLQAYCSFGGTSC---SNN 182
++E +++ G+ P VNQ+E++ + + + +C++++I L+AY G ++N
Sbjct: 164 NIEEILKI-AGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLGPLQKRPENSN 222
Query: 183 SLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIPEEDM 241
L + A K T +Q+LL W + + I + + I + +++ +F + ++++
Sbjct: 223 ELPFYNYIDELASKYGKTDSQILLNWVYNRGILPITTSSKTQRIIDAQNIFSFNLTKDEV 282
Query: 242 KALNQL 247
L +L
Sbjct: 283 DTLTKL 288
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 80.6 bits (190), Expect = 4e-14
Identities = 57/219 (26%), Positives = 106/219 (48%), Gaps = 25/219 (11%)
Query: 55 DHGSRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKR-----------NTKMRELS 103
+H E+ + SLE L L+Y+D+YLIH P + +T+ ++
Sbjct: 109 NHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIA 168
Query: 104 -WCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
W ++ + +G+ ++G+SNF + +++ + P+ QVE H Y+ Q L +FC+
Sbjct: 169 VWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAK-IKPSNLQVEVHAYHQQKPLIEFCQ 227
Query: 163 QHHITLQAYCSFGGTSCSNN-----------SLLNDPVVVSTALKLEVTPAQVLLVWALQ 211
++ I + Y G + PVV A K + Q+LL +Q
Sbjct: 228 KNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHHLVQ 287
Query: 212 QDVAVIPKAVHPEHIKENRSL-NFKIPEEDMKALNQLSE 249
+ +AVI + +P H+KEN + +F++ E++MK+L+ L +
Sbjct: 288 KGIAVIFSSKNPNHLKENIEIFDFELTEDEMKSLDALDK 326
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 80.2 bits (189), Expect = 5e-14
Identities = 55/188 (29%), Positives = 95/188 (50%), Gaps = 15/188 (7%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A + SL+ L+++ +DLY +H+P R+ ++E + + L D G + +GV
Sbjct: 82 RACENSLKRLNVKTIDLYQLHWPN---------RHVDIKE-TMKAMEHLVDTGMIRYIGV 131
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWHPY--YTQSSLYKFCKQHHITLQAYCSF-GGTS 178
SNF V L+ M + NQVE++P Y + + +FC+++ I++ AY G
Sbjct: 132 SNFNVNELKSAMSAMSKYEIVSNQVEYNPLVRYIEPEISEFCRKNSISIIAYSPLMHGHD 191
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIP 237
S P + A K T QV+L W L ++ IPK+ PEH+ EN +S+N +
Sbjct: 192 IDPISKDESPFNI-IANKRNATVRQVILAWILSKNFFAIPKSNVPEHVIENVKSMNINLS 250
Query: 238 EEDMKALN 245
E+ ++
Sbjct: 251 SEETSMID 258
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 79.8 bits (188), Expect = 6e-14
Identities = 55/190 (28%), Positives = 93/190 (48%), Gaps = 14/190 (7%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
RA + ++SLE+L +YVDL L+H+P LP + L W L + ++ G A
Sbjct: 98 RAAASIRRSLEDLRTDYVDLLLVHWP----LPTLYGGDVA---LPWPALEDAFNAGGARA 150
Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTS 178
+G+SN+ H+E + E + P V QVE HP++ + L + + + +A+ +
Sbjct: 151 IGLSNYEREHVEAVREVAT-VAPHVLQVESHPFFPNADLRAYAQGLGMVFEAW-----SP 204
Query: 179 CSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKENRSL-NFKIP 237
+ + DP +V +L V P QV L WAL + V PK + E + N + +F +
Sbjct: 205 LARGRAVTDPTLVEIGAELGVGPTQVTLRWALDRGHVVFPKTLSRERMAANFDVFSFSLD 264
Query: 238 EEDMKALNQL 247
E ++ L
Sbjct: 265 PEQTARIDAL 274
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 79.8 bits (188), Expect = 6e-14
Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 16/187 (8%)
Query: 65 QKSLENLDLEYVDLYLIHFPG-GAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSN 123
Q S + L + +DL LIH+P ++P E+ + L + DG + +GVSN
Sbjct: 77 QVSRDKLQRDTIDLALIHWPSPNDEVPVEETLDA---------LQKAQQDGLIKHLGVSN 127
Query: 124 FTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNS 183
FT+ L NQ+E HP++ ++ CKQ + + AY + +NS
Sbjct: 128 FTIDLLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKVTAYLPLAKGAVMDNS 187
Query: 184 LLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RSLNFKIPEEDMK 242
++ + A K V+PAQV + W L D IP +H+K N + + K+ ++DMK
Sbjct: 188 VMQN-----IAEKHNVSPAQVAIAWQLANDYIAIPSTTKVDHLKSNFDAQSLKLDQDDMK 242
Query: 243 ALNQLSE 249
A+ + +
Sbjct: 243 AIADIDK 249
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 79.8 bits (188), Expect = 6e-14
Identities = 58/189 (30%), Positives = 93/189 (49%), Gaps = 20/189 (10%)
Query: 59 RAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNA 118
R +A +SL+ L L+YV+L L+H+P +P D+ L E+ G+
Sbjct: 82 RHSEAVDESLDRLGLDYVNLILLHWPIN-DMPIADQVG---------PLAEIKRSGRAKL 131
Query: 119 VGVSNFTVAH-LEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
+G+SN+ A LE + S L A Q E+HP Q + K + + +Y G
Sbjct: 132 IGISNYNQAQFLEAVSASEEPL--AAIQCEYHPMLDQDPILKTARGFDMMFTSYSPLG-- 187
Query: 178 SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQ-DVAVIPKAVHPEHIKENRSL-NFK 235
+++P + A + TPAQ++L W LQQ +VA IPKA HI++N + +F+
Sbjct: 188 ---RGEAMSNPAIERLAEQHGKTPAQIILRWHLQQANVAAIPKATSKAHIEQNFDIFDFE 244
Query: 236 IPEEDMKAL 244
+ DMK +
Sbjct: 245 LSATDMKTI 253
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 79.8 bits (188), Expect = 6e-14
Identities = 57/205 (27%), Positives = 99/205 (48%), Gaps = 18/205 (8%)
Query: 58 SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWC-KLTELYDD--- 113
+R ++ SL++L L+YVDL L+H+P ++D R + + ++ DD
Sbjct: 85 NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWIT 144
Query: 114 -----------GKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
G+ ++GVSN + +L+ L++ VPAVNQ E HPY Q +F +
Sbjct: 145 TYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVK-TVPAVNQFEIHPYLPQKKEIEFNE 203
Query: 163 QHHITLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVH 222
+H I + A+ G+S L +P+ V A K + VL+ W + Q AV+PK
Sbjct: 204 KHGILVTAFSPL-GSSTGALKLHENPIAVEIAQKHNTSTGSVLINWHVSQKRAVLPKTRS 262
Query: 223 PEHIKENRSLNFKIPEEDMKALNQL 247
E + N + + + D+ L+++
Sbjct: 263 IERVVAN-GMKVPLDQGDLDKLDKI 286
>UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases,
related to diketogulonate reductase; n=1; Yersinia
frederiksenii ATCC 33641|Rep: COG0656: Aldo/keto
reductases, related to diketogulonate reductase -
Yersinia frederiksenii ATCC 33641
Length = 312
Score = 79.4 bits (187), Expect = 9e-14
Identities = 54/189 (28%), Positives = 95/189 (50%), Gaps = 19/189 (10%)
Query: 62 QAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGV 121
+A SL + +Y+DL+L+H+ + T ++E+ EL G++ GV
Sbjct: 135 KACNASLSRMGTQYLDLFLLHWRDSS---------TDLKEVV-NTFEELRQSGQIRRWGV 184
Query: 122 SNFTVAHLEGLMESNHGLVPAVNQVEWH--PYYTQSSLYKFCKQHHITLQAYCSFGGTSC 179
SNF ++ LE L G NQV + + L +C++H + + AY G
Sbjct: 185 SNFEISDLEELFAIPGGEQCVTNQVRYSLMDRNIEQDLIPWCEKHGLPIMAYSPLG---- 240
Query: 180 SNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAV-IPKAVHPEHIKEN-RSLNFKIP 237
SLL + ++S A +L+ TPA V + W ++ + IP A EH+KEN ++L+ K+
Sbjct: 241 -KGSLLKNDTLISVATRLKCTPAAVAIAWTMRNGETISIPSAGSSEHVKENAKALSLKLT 299
Query: 238 EEDMKALNQ 246
+D++ L++
Sbjct: 300 IDDLRELDK 308
>UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75;
cellular organisms|Rep: Aldehyde reductase, putative -
Leishmania major
Length = 286
Score = 79.4 bits (187), Expect = 9e-14
Identities = 58/183 (31%), Positives = 91/183 (49%), Gaps = 15/183 (8%)
Query: 67 SLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVGVSNFTV 126
SL+N+ +Y+DLYL+H+ G ++P + E C + EL GK+ GVSNF V
Sbjct: 100 SLQNIGTDYLDLYLLHWRG--RVP--------LSETVTC-MEELVKSGKIRRWGVSNFDV 148
Query: 127 AHLEGLMESNHGLVPAVNQVEWH--PYYTQSSLYKFCKQHHITLQAYCSFGGTSCSNNSL 184
++ L G AVNQV +H + L + ++H + + AYC + L
Sbjct: 149 DDMKELWRVPGGDKCAVNQVLYHLGSRGIEYDLLPWLREHKVPVMAYCPIAQAGELKSEL 208
Query: 185 LNDPVVVSTALKLEVTPAQVLLVWALQQ-DVAVIPKAVHPEHIKENRSL-NFKIPEEDMK 242
VV S A + T QVLL + L+ V IP++ +P H +EN + + ++ E DM
Sbjct: 209 YKSTVVRSVAARHNATVTQVLLAFVLRSGHVIAIPRSSNPAHTEENAAADSIELTEADMA 268
Query: 243 ALN 245
L+
Sbjct: 269 QLD 271
>UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 151
Score = 79.0 bits (186), Expect = 1e-13
Identities = 45/135 (33%), Positives = 72/135 (53%), Gaps = 5/135 (3%)
Query: 103 SWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCK 162
SW L EL GK+ ++GVSNF V L+ L + + P+ Q + P+Y + ++CK
Sbjct: 2 SWRALEELVSQGKIRSIGVSNFEVKDLKKLKDIAK-VPPSAIQNFFTPFYQDKATRQYCK 60
Query: 163 QHHITLQAYCSFGGT----SCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIP 218
+++I Y + GG N + N+ + + T +QV+L WAL+QDV VIP
Sbjct: 61 ENNIKYMGYSTLGGMYVREGFDKNPVQNNFELQRIGGVFDATVSQVVLKWALEQDVLVIP 120
Query: 219 KAVHPEHIKENRSLN 233
++ P HI+ N L+
Sbjct: 121 QSRTPNHIRTNFHLD 135
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.133 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 300,279,600
Number of Sequences: 1657284
Number of extensions: 12188689
Number of successful extensions: 29552
Number of sequences better than 10.0: 479
Number of HSP's better than 10.0 without gapping: 303
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 28026
Number of HSP's gapped (non-prelim): 804
length of query: 262
length of database: 575,637,011
effective HSP length: 99
effective length of query: 163
effective length of database: 411,565,895
effective search space: 67085240885
effective search space used: 67085240885
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
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