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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000695-TA|BGIBMGA000695-PA|IPR001395|Aldo/keto reductase
         (262 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0)               130   9e-31
SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.)             100   2e-21
SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.)               83   3e-16
SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.)              77   1e-14
SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0)                 75   4e-14
SB_5128| Best HMM Match : No HMM Matches (HMM E-Value=.)               54   9e-08
SB_56184| Best HMM Match : No HMM Matches (HMM E-Value=.)              42   4e-04
SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16)             36   0.034
SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1)              31   0.96 
SB_8646| Best HMM Match : 7tm_1 (HMM E-Value=1.2e-27)                  30   1.7  
SB_17842| Best HMM Match : RVT_1 (HMM E-Value=2.2e-29)                 29   3.9  
SB_38097| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   5.1  
SB_1004| Best HMM Match : CPSase_sm_chain (HMM E-Value=0)              28   6.8  
SB_51892| Best HMM Match : WD40 (HMM E-Value=8.7e-14)                  28   8.9  

>SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0)
          Length = 333

 Score =  130 bits (315), Expect = 9e-31
 Identities = 76/198 (38%), Positives = 112/198 (56%), Gaps = 19/198 (9%)

Query: 54  SDHGSRAEQ-AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYD 112
           ++HG +    A+ KSL  L L YVDLYLIHFP  + +             SW  + +L  
Sbjct: 138 TEHGYKETMDAFYKSLTRLGLGYVDLYLIHFPVPSGVVG-----------SWQAMIDLRS 186

Query: 113 DGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYC 172
            G + ++GVSNF + HLE L +   G+VPAVNQ+E HP+     L ++CK+H+IT+QA+ 
Sbjct: 187 RGLIRSIGVSNFNIQHLEALRQQT-GVVPAVNQIEVHPFLQMKELTQYCKRHNITIQAF- 244

Query: 173 SFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
               +  +    L DP++   A K   T AQ+L+ W+LQ+  A IPK+   E IKEN + 
Sbjct: 245 ----SPLTKGEKLCDPILSYVAKKYNKTTAQILVRWSLQKGYACIPKSAQLERIKENAKV 300

Query: 232 LNFKIPEEDMKALNQLSE 249
            +F I   DM+ ++ L E
Sbjct: 301 FDFSIDMADMELIDGLEE 318


>SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 340

 Score = 99.5 bits (237), Expect = 2e-21
 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 16/197 (8%)

Query: 67  SLENLDLEYVDLYLIHFP-----GGAKLPAEDKRNTKMREL----SWCKLTELYDDGKVN 117
           SL++L L+Y+DLYLIH+P     G    P +++ N          +W  + +L D+G V 
Sbjct: 94  SLKDLGLDYLDLYLIHWPLSFRDGDEFFPKDEQGNVLYAYHDPCDTWKAMEKLVDEGLVK 153

Query: 118 AVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAYCSFGG- 176
           A+G+SNF    ++ +      + P  NQVE HP   Q+ L    K+H+I   AY   G  
Sbjct: 154 AIGLSNFNSKQVDDICAIAR-IKPVANQVECHPLLNQAKLIDHHKKHNIQTIAYSPLGSL 212

Query: 177 ----TSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
                   +  ++ DP +V+ A +   T AQ+ + + +Q+ V VIPK+V PE IK N + 
Sbjct: 213 DRPWAKPDDPHVMRDPTMVAMADRYSRTVAQICIRFQIQRGVLVIPKSVTPERIKSNFQV 272

Query: 232 LNFKIPEEDMKALNQLS 248
            +F++  EDM  +  L+
Sbjct: 273 FDFELSAEDMATIEGLN 289



 Score = 36.7 bits (81), Expect = 0.019
 Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 11 TFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYR 49
          T  LNNG+ MP +GLGT++ +    V   V +A++ GYR
Sbjct: 3  TVKLNNGLEMPVLGLGTWKSKPGQ-VENAVKFAIKEGYR 40


>SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 619

 Score = 82.6 bits (195), Expect = 3e-16
 Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 13/198 (6%)

Query: 62  QAYQKSLENLDLEYVDLYLIHFPGGAKLP---AEDKRNTKMRELSWCKLTELYDDGKVNA 118
           ++ + SL  L  +Y+DL+LIH           AE +     +E SW  + EL+  GK+ +
Sbjct: 411 KSVEMSLRALSTDYIDLFLIHSKTCDDFLLTCAEGEPRGTWKE-SWKAMEELHRQGKIRS 469

Query: 119 VGVSNFTVAHLEGLMESNHGLVPAVNQVEW-HPYYTQSSLYKFCKQHHITLQAYCSFGGT 177
           +GVSNF V  L+ L+  N   VP      W  P++      +FC +H I    Y + G  
Sbjct: 470 LGVSNFNVDELQELV--NFATVPVSAVQNWFDPFHQDRKARRFCNKHGIRYIGYSTLGTQ 527

Query: 178 SCSNNSLLNDPVVVSTALK-----LEVTPAQVLLVWALQQDVAVIPKAVHPEHIKEN-RS 231
               + L  +PV+ S          E   +QV+L WA+ Q+V VIP++ +  +I  N RS
Sbjct: 528 WVYFHGLKTNPVLQSKVFSEISSHYEYVISQVVLRWAIHQNVTVIPRSRNSRNIYLNFRS 587

Query: 232 LNFKIPEEDMKALNQLSE 249
           L+  + E +++ +  +++
Sbjct: 588 LDLSLNENEIEMITNVTD 605



 Score = 35.5 bits (78), Expect = 0.044
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 9   PTTFVLNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRMFAPSDHGSRAEQAYQKSL 68
           P   +L +G  MP +G GT  + +    + VV  ALE GYR+   +     +E    K++
Sbjct: 326 PADVLLASGYTMPVMGFGTATLGED--TLSVVKTALETGYRLIDTAQGYPLSEPQVAKAI 383

Query: 69  ENLDLEYVDLYLI 81
            +  +   D+++I
Sbjct: 384 ADSGIPRKDIFII 396


>SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 394

 Score = 77.4 bits (182), Expect = 1e-14
 Identities = 44/120 (36%), Positives = 71/120 (59%), Gaps = 13/120 (10%)

Query: 53  PSDHG-SRAEQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELY 111
           PS+ G S A +  ++S++ LD+ YVDL+LIH P    + A           ++  L  L 
Sbjct: 95  PSEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRPGNIIA-----------AYDALLTLK 143

Query: 112 DDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYKFCKQHHITLQAY 171
           ++G + +VGVSNF V HLE L ++     PA+NQ+E +P++ Q  + K+C +H IT++ Y
Sbjct: 144 EEGLIRSVGVSNFGVHHLEELRKAGCR-TPAINQIEINPFWRQEEIIKYCNKHGITVEGY 202


>SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0)
          Length = 407

 Score = 75.4 bits (177), Expect = 4e-14
 Identities = 48/122 (39%), Positives = 66/122 (54%), Gaps = 10/122 (8%)

Query: 49  RMFAPSDHGSRAEQAYQKSLENLDLEYVDLYLIHFP----GGAKLP---AED--KRNTKM 99
           +++  S H      A Q +L+NL L+Y+DLYLIH P     G +LP   AE       + 
Sbjct: 117 KLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEG 176

Query: 100 RELSWCKLTELYDDGKVNAVGVSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSLYK 159
            + +W  +  L   G   A+GVSNF+V  L  L+E+   +VPA NQVE HPY  Q  L +
Sbjct: 177 VQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLET-ASIVPACNQVELHPYLPQEKLKE 235

Query: 160 FC 161
           FC
Sbjct: 236 FC 237



 Score = 44.0 bits (99), Expect = 1e-04
 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 9/108 (8%)

Query: 152 YTQSSLYKFCKQHHITLQAYCSFG--GTSCSNNSL------LNDPVVVSTALKLEVTPAQ 203
           +  S    FC    I L AY   G  G       L      + +PV+   A K   + A+
Sbjct: 276 FWDSKCKDFCDSKGILLTAYSPLGNPGRLVPKERLEREPKVMEEPVIKEIAAKHNCSVAR 335

Query: 204 VLLVWALQQDVAVIPKAVHPEHIKENRS-LNFKIPEEDMKALNQLSEK 250
           VLL W +Q+   V+PK+   +H+ +N S L   + +++M A+  ++ +
Sbjct: 336 VLLRWGIQRGYPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTR 383


>SB_5128| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2102

 Score = 54.4 bits (125), Expect = 9e-08
 Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 4/88 (4%)

Query: 150  PYYTQSSLYKFCKQHHITLQAYCSFGGT----SCSNNSLLNDPVVVSTALKLEVTPAQVL 205
            P+Y   +  ++CK+++I    Y + GG         N + N+  +       + T +QV+
Sbjct: 1328 PFYQDKATRQYCKENNIKYMGYSTLGGMYVREGFDKNPVQNNFELQRIGGVFDATVSQVV 1387

Query: 206  LVWALQQDVAVIPKAVHPEHIKENRSLN 233
            L WAL+QDV VIP++  P HI+ N  L+
Sbjct: 1388 LKWALEQDVLVIPQSRTPNHIRTNFHLD 1415


>SB_56184| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 242

 Score = 42.3 bits (95), Expect = 4e-04
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 13/118 (11%)

Query: 61  EQAYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTKMRELSWCKLTELYDDGKVNAVG 120
           E + QKS++ + ++ +D+   H+         DKR       +   L+EL  +GK+  + 
Sbjct: 7   EASIQKSMKRMAVDKLDMVQFHW-----WDYSDKRYLD----ALLHLSELQSEGKIQEIS 57

Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWH--PYYTQSSLYKFCKQHHITLQAYCSFGG 176
           ++NF    ++ +  ++HG+  + NQ+++          + KFC  H I+L AY +  G
Sbjct: 58  LTNFDTNRMQEI--TDHGIKISSNQIQFSLIDRRANEKMVKFCLDHGISLLAYGTIAG 113


>SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16)
          Length = 195

 Score = 35.9 bits (79), Expect = 0.034
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 13/85 (15%)

Query: 41  DYALEAGYRMFAPSDHGSRAEQ--AYQKSLENLDLEYVDLYLIHFPGGAKLPAEDKRNTK 98
           DY  E G       ++ S  +   + +KSLE L ++ +DLYL+H+ G  ++P E+  +  
Sbjct: 23  DYEFELGTLSKVRPENASEMKMMLSCEKSLERLGIDRIDLYLLHWEG--RVPLEETVDA- 79

Query: 99  MRELSWCKLTELYDDGKVNAVGVSN 123
                     EL D+G +   GVSN
Sbjct: 80  --------FRELVDEGMIARWGVSN 96


>SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1)
          Length = 93

 Score = 31.1 bits (67), Expect = 0.96
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 14 LNNGIMMPSIGLGTYRIRQSDIVMQVVDYALEAGYRM 50
          L++G  +P  GLG Y + +     Q V +ALE GYRM
Sbjct: 3  LSDGYKIPRFGLGLYDLDEKH-TKQAVLWALENGYRM 38


>SB_8646| Best HMM Match : 7tm_1 (HMM E-Value=1.2e-27)
          Length = 522

 Score = 30.3 bits (65), Expect = 1.7
 Identities = 16/43 (37%), Positives = 23/43 (53%)

Query: 167 TLQAYCSFGGTSCSNNSLLNDPVVVSTALKLEVTPAQVLLVWA 209
           TL+   SFG TS +N       +VV T   + + P QV+ +WA
Sbjct: 190 TLRRSLSFGATSSANVRATKMFLVVVTVFSIFMLPNQVIWLWA 232


>SB_17842| Best HMM Match : RVT_1 (HMM E-Value=2.2e-29)
          Length = 1167

 Score = 29.1 bits (62), Expect = 3.9
 Identities = 11/33 (33%), Positives = 16/33 (48%)

Query: 154 QSSLYKFCKQHHITLQAYCSFGGTSCSNNSLLN 186
           Q++ YKFC   H   + +C   G  C+N    N
Sbjct: 203 QAAKYKFCGYSHTLKKEFCKAWGKRCNNRKAPN 235


>SB_38097| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1099

 Score = 28.7 bits (61), Expect = 5.1
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 9/69 (13%)

Query: 161 CKQHHITLQAYCS--FGGTSCSNNSLLNDPVVVSTALKLE------VTPAQVLLVWALQQ 212
           CK   +T+QA+C   FGG++     L ++     +   LE      + P + L  +   Q
Sbjct: 429 CKHSFVTVQAFCDWLFGGSNAGYTCLAHNFKGYDSYFILEYLFANGIKPKEALATYC-HQ 487

Query: 213 DVAVIPKAV 221
           DV V+ KAV
Sbjct: 488 DVEVLKKAV 496


>SB_1004| Best HMM Match : CPSase_sm_chain (HMM E-Value=0)
          Length = 2007

 Score = 28.3 bits (60), Expect = 6.8
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 2/34 (5%)

Query: 2   ASSDPIIPTTFVLNNGIMMPSIGLGTYRIRQSDI 35
           +SS P +P      NGI +PS+G  +Y  R S I
Sbjct: 169 SSSSPTVPNK--TTNGISVPSVGRSSYSTRVSPI 200


>SB_51892| Best HMM Match : WD40 (HMM E-Value=8.7e-14)
          Length = 353

 Score = 27.9 bits (59), Expect = 8.9
 Identities = 12/37 (32%), Positives = 21/37 (56%)

Query: 121 VSNFTVAHLEGLMESNHGLVPAVNQVEWHPYYTQSSL 157
           V   + ++ E  +ES HG    + QV+W+P Y ++ L
Sbjct: 96  VHKCSCSYNEQYLESFHGHTGPIYQVKWNPLYPEAFL 132


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.317    0.133    0.396 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 8,863,984
Number of Sequences: 59808
Number of extensions: 358584
Number of successful extensions: 788
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 758
Number of HSP's gapped (non-prelim): 19
length of query: 262
length of database: 16,821,457
effective HSP length: 81
effective length of query: 181
effective length of database: 11,977,009
effective search space: 2167838629
effective search space used: 2167838629
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 59 (27.9 bits)

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