Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000692-TA|BGIBMGA000692-PA|IPR001367|Iron dependent
repressor, IPR003593|AAA ATPase, IPR013602|Dynein heavy chain,
N-terminal region 2, IPR011704|ATPase associated with various cellular
activities, AAA-5
(2768 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein. 1283 0.0
AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy ch... 1281 0.0
AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein. 1281 0.0
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 1278 0.0
AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dy... 1263 0.0
AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein. 1163 0.0
AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein. 1133 0.0
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch... 1053 0.0
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c... 1053 0.0
AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein. 1053 0.0
AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy cha... 1045 0.0
AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein. 1018 0.0
AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy... 921 0.0
AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy... 921 0.0
AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy c... 921 0.0
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 883 0.0
AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein, ax... 655 0.0
AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1 ... 535 e-151
AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens ... 460 e-128
AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, he... 390 e-107
AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein. 390 e-107
BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein. 390 e-107
BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein. 380 e-104
AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein. 380 e-104
AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain prot... 372 e-102
BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein. 286 7e-76
AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy... 257 4e-67
AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein. 252 1e-65
Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy cha... 245 2e-63
AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein. 245 2e-63
Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy cha... 230 5e-59
AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein. 227 3e-58
Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy cha... 219 1e-55
AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens ... 202 1e-50
AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein. 188 3e-46
AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy ... 184 3e-45
AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy ... 182 2e-44
AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens ... 181 4e-44
AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy ... 180 5e-44
U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heav... 180 9e-44
AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein. 175 1e-42
BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein pr... 175 2e-42
AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy ... 173 1e-41
Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy ... 172 2e-41
U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy ... 153 9e-36
AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein, ax... 145 2e-33
AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein. 142 1e-32
AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein. 141 3e-32
U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isoty... 140 5e-32
BC113424-1|AAI13425.1| 408|Homo sapiens FLJ37357 protein protein. 133 7e-30
BC104884-1|AAI04885.1| 408|Homo sapiens FLJ37357 protein protein. 133 7e-30
AK094676-1|BAC04400.1| 408|Homo sapiens protein ( Homo sapiens ... 133 7e-30
AC096770-2|AAY24108.1| 408|Homo sapiens unknown protein. 133 7e-30
Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy cha... 132 2e-29
U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heav... 132 2e-29
U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein. 128 2e-28
U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy cha... 128 4e-28
U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy cha... 126 1e-27
AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy ... 123 1e-26
AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy ... 115 2e-24
AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein pr... 109 1e-22
U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy cha... 108 2e-22
Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy cha... 104 4e-21
Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy cha... 104 5e-21
AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein. 103 9e-21
AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy ... 103 1e-20
AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy ... 101 5e-20
Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy cha... 96 1e-18
L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein. 93 1e-17
AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy ... 88 4e-16
U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein. 85 5e-15
U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein. 79 2e-13
AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens ... 79 3e-13
AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy ... 75 5e-12
U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein. 74 8e-12
AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy ... 73 1e-11
AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens ... 71 5e-11
U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy cha... 69 2e-10
AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy... 67 1e-09
U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein. 66 2e-09
U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein. 64 7e-09
U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein. 63 2e-08
AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy c... 59 2e-07
AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein pr... 58 3e-07
U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy cha... 45 0.003
AF311855-1|AAG42473.1| 2564|Homo sapiens spectrin beta IV protein. 42 0.042
AY004227-1|AAF93173.1| 2149|Homo sapiens betaIV spectrin isoform... 41 0.055
AY004226-2|AAF93172.1| 1307|Homo sapiens betaIV spectrin isoform... 41 0.055
AF324064-1|AAQ14859.1| 2002|Homo sapiens beta spectrin IV protein. 41 0.055
AF324063-1|AAQ14860.1| 2564|Homo sapiens non-erythrocytic beta-s... 41 0.055
AF082075-1|AAG38874.1| 2559|Homo sapiens beta4sigma1 spectrin pr... 41 0.055
AB046862-1|BAB13468.1| 1997|Homo sapiens KIAA1642 protein protein. 41 0.055
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 40 0.096
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 40 0.096
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 40 0.096
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 40 0.096
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 40 0.096
AF311856-1|AAG42474.1| 678|Homo sapiens spectrin beta IV protein. 39 0.29
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 37 0.90
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 37 0.90
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 37 1.2
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 37 1.2
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 37 1.2
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 37 1.2
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 37 1.2
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 37 1.2
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 36 1.6
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 36 1.6
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 36 1.6
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 36 1.6
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 36 1.6
BC071599-1|AAH71599.1| 1121|Homo sapiens pleckstrin homology dom... 36 1.6
BC033239-1|AAH33239.1| 748|Homo sapiens PLEKHA7 protein protein. 36 1.6
AL833308-1|CAD89924.1| 878|Homo sapiens hypothetical protein pr... 36 1.6
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 36 1.6
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 36 1.6
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 36 2.1
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 36 2.1
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 36 2.7
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 36 2.7
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 36 2.7
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 36 2.7
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 36 2.7
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 36 2.7
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 36 2.7
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 36 2.7
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 36 2.7
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 36 2.7
BC111765-1|AAI11766.1| 597|Homo sapiens chromosome 11 open read... 35 3.6
AK093028-1|BAC04023.1| 286|Homo sapiens protein ( Homo sapiens ... 35 3.6
BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine nucleo... 35 4.8
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 35 4.8
AJ238899-1|CAC00686.1| 425|Homo sapiens guanine nucleotide exch... 35 4.8
AC016692-1|AAX93288.1| 582|Homo sapiens unknown protein. 35 4.8
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 34 6.3
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 34 6.3
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 34 6.3
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 34 6.3
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 34 6.3
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein. 34 6.3
X06882-1|CAA29999.1| 375|Homo sapiens cd14 protein precursor pr... 34 8.4
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 34 8.4
BC119717-1|AAI19718.1| 438|Homo sapiens C1orf67 protein protein. 34 8.4
BC119716-1|AAI19717.1| 438|Homo sapiens C1orf67 protein protein. 34 8.4
BC070236-1|AAH70236.1| 116|Homo sapiens NADH dehydrogenase (ubi... 34 8.4
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 34 8.4
AL590547-1|CAH73045.1| 430|Homo sapiens chromosome 1 open readi... 34 8.4
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 34 8.4
>AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein.
Length = 4355
Score = 1283 bits (3178), Expect = 0.0
Identities = 718/1794 (40%), Positives = 1016/1794 (56%), Gaps = 87/1794 (4%)
Query: 969 LAKTASPEDLTTDIVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFAL 1028
+A+ EDL +I M S EGE V L + NVEDWL +VE +M ASV ++ A+
Sbjct: 1385 IARLLFQEDL--EITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAI 1442
Query: 1029 KEYMVNERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLN 1088
+ Y R WV P QV + Q W V E LR + + C L+
Sbjct: 1443 RAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAG-NLRSQL----FPQLC-QQLS 1496
Query: 1089 DLAALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDI 1148
DL AL R L+ + R VL ALI I+VHA+D +S +++++V NDF+W+ +RYYW +
Sbjct: 1497 DLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNN- 1555
Query: 1149 DNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXX 1208
+ R +A +IYG+EYLG G LVITPLTDRCYL L GAL L
Sbjct: 1556 -DLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTE 1614
Query: 1209 XXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQ 1268
DL K+LAIQ VVFNCS+ LD+ MG+FF GLA++GAW CFDEFNRIDIEVLSV+AQQ
Sbjct: 1615 TTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQ 1674
Query: 1269 LITIRNAKVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVP 1328
+ TI+ A+ + RFMFEG EI LV +CA FITMNPGYAGRTELPDNLKALFRP++MMVP
Sbjct: 1675 ITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVP 1734
Query: 1329 DYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALK 1388
DYA+I E+ LYS GF + LAKK+ +KLSSEQLS QDHYDFGMRAVK+V+ AG LK
Sbjct: 1735 DYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLK 1794
Query: 1389 RANPDQHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKII 1448
R NP +EE+ L A+ D N+PKFL D LF+GI+SDLFP + DYG++++ I+
Sbjct: 1795 RENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREA 1854
Query: 1449 MLERKLQIEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLY-ENGVE 1507
L+ + K IQL+ET +VR G+MLVGPTG GK+ VL T L + +
Sbjct: 1855 CRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSIS 1914
Query: 1508 GSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDG 1567
G Y+ V Y++NPKS+T+G+LYGE +L T EW DGI +R + + +W + DG
Sbjct: 1915 GGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDG 1974
Query: 1568 PVDAVWIENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYID 1627
PVDA+WIENMNTVLDDNK LCLS+ E IKLT + M+FEV DLA ASPATVSRCGMVY++
Sbjct: 1975 PVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLE 2034
Query: 1628 PNEMGYLPFVRSWLQE-----GVEKNLFNQENSDFIYELFKMTQVGLDHV--NYNCGVGI 1680
P+ +G +PF+ WL++ + F F+ E + + V + NC + +
Sbjct: 2035 PSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTM 2094
Query: 1681 KQVDISKVSAQCFLLGALLAEPGDRFADKAALKIY--IAHCFIFCYVWCIGGNILEMNRQ 1738
+ + CF L E + + +I I FIF +W +G R
Sbjct: 2095 SLLKL----LDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRT 2150
Query: 1739 SFEEVIKRQFEEYEEAEYYPQGFNFFDMYM------------DTRQRKLKV----WAEII 1782
SF ++ + E + +P+ FD + D + +V W +
Sbjct: 2151 SFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSS 2210
Query: 1783 PEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKT-CIAVEILNRM 1841
F + + +VPT+DTV+ +L + LL KPV+ G TG GKT I+ ++L +
Sbjct: 2211 APFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNL 2270
Query: 1842 SLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDV 1901
+L Y+ L FSA+TS+ +TQ+ I+ +LDKR + G PLG+ I FIDD+NMP L+
Sbjct: 2271 ALD--YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALET 2328
Query: 1902 YGAQPTIELLRQFLDFGGVYDRDKL-YWKDILDVVLSCSCAPPGGGRNPLTARFVRHFAM 1960
YGAQP IELLRQ++D GG YDR + +K+++D+ C+ PPGGGRN +T R +RHF
Sbjct: 2329 YGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNY 2388
Query: 1961 LYIAAPNADAMKTIFKAILKGHMEDFV------------PEVSVLGESIVNAAVEVYLKI 2008
L A + + K IF IL ++ + P ++ E +V A + VY I
Sbjct: 2389 LSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATI 2448
Query: 2009 CAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINI 2068
++LLPTPAKSHY FNLRDLSK QG+L A A + +LRL+YHE RVF DRL+N
Sbjct: 2449 TSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNE 2508
Query: 2069 QDKSYFYHLMASVCEKNFQTPILSV-PDEPIIEHPPLLLFGDFLNSSVPKENRTYQEIPD 2127
+D+S+F L+ C + ++ V P +PI L+GDF+ S + ++Y+ I
Sbjct: 2509 EDRSWFDQLLKR-CMEQWEVTFNKVCPFQPI-------LYGDFM--SPGSDVKSYELITS 2558
Query: 2128 ISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRR 2187
SK+M V++EY+++YN A++ LVLF D G+ L++G GGSGR
Sbjct: 2559 ESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRS 2618
Query: 2188 SVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEF 2247
S+ LA H+ E +C +EL +NY E+ DD++ + ++AG+ FLF+DTQI E F
Sbjct: 2619 SLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESF 2678
Query: 2248 LEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHL 2307
LEDINN+LNSG++PNL+ D +Q+ + R + G+ P+ + + + RVR +H+
Sbjct: 2679 LEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPT-KANLMAAYTGRVRSNIHM 2737
Query: 2308 CICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPL----GNQEIIT 2363
+CMSP+GE FR R R FPSLVNCCTIDWF +WP EAL SVA L + +QE I
Sbjct: 2738 VLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQ 2797
Query: 2364 KISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRI 2423
+ ++CV +HQ+V E+ R+ Y TP S + ++R+
Sbjct: 2798 GLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRM 2857
Query: 2424 SCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXX 2483
GL KL T + V M++ + M P+L A +++ +E++K++ A+E + +V
Sbjct: 2858 KSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEE 2917
Query: 2484 XXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVM 2543
L A+PA++ D+ E++A Q+PP V+ V+
Sbjct: 2918 IKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVI 2977
Query: 2544 EPVCILMGVKPD--------------WDSTKKLLADV-NFIGKLADYDKDHIPDATLKKI 2588
E VCI+ G+KP W+ K LL D +F+ L +DKD+I D +K I
Sbjct: 2978 EAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAI 3037
Query: 2589 KVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMA 2648
+ Y+ +++F P T+ KVSK C S+ WV+A+ Y V + VEPK EA L
Sbjct: 3038 QPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQR 3097
Query: 2649 VLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQAL 2702
+L ++ + +E +A M + + ++ +L+ + RL RAGK+ L
Sbjct: 3098 ILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKVRTLL 3151
Score = 252 bits (617), Expect = 1e-65
Identities = 160/605 (26%), Positives = 285/605 (47%), Gaps = 12/605 (1%)
Query: 352 EFRKLCEKFVKQMEAIEDVV-SYQPLGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGR 410
E R++ +++ E ++ + S +G ++ ++ + K L VL++
Sbjct: 803 EVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLH 862
Query: 411 ECIDGILEGVENISGDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGE 470
+ +D I E +IS I + P + EL + G+ R+ +M E
Sbjct: 863 KEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDE 922
Query: 471 FNIPIPPEDMTQFLGLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
F + +D S S + ++ + + F D N + L+
Sbjct: 923 FLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQ 982
Query: 531 DEVTQPWLYDEKSDLEKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAI 590
V ++ E S ++ + + ++L C ++IF +P ++L +
Sbjct: 983 LVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMV 1042
Query: 591 NDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSNTIV 650
+ + LW + +W +SW ++P + +D ++++ + + F + K + +
Sbjct: 1043 KEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV---EAFKTMHKCVKQFKDM 1099
Query: 651 PKCKEL-------IDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFE 703
P C+E+ I+ K +P+I LRNP ++ RHW + ++ P +
Sbjct: 1100 PACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCL 1159
Query: 704 ELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEI 763
E+ H + + +VA A E +E L K+E+ W+ + F V+ +K A D Y+L DE
Sbjct: 1160 EMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYK-ATDTYILKSPDEA 1218
Query: 764 QASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSA 823
LD+ + + S P + R+ W L+L + LEEW CQ++W+YLE IFS+
Sbjct: 1219 SQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSS 1278
Query: 824 PDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKC 883
DI +QLP E++ + +++ WK IM+ + + + ++ + N++LD + K
Sbjct: 1279 EDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKG 1338
Query: 884 LEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFGVKFPESE 943
L YLETKR AFPRF+FLS+DELLEIL+QT++P AVQPHLRKCF+ IA+L F +
Sbjct: 1339 LSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITH 1398
Query: 944 MEIAE 948
M AE
Sbjct: 1399 MYSAE 1403
Score = 57.6 bits (133), Expect = 6e-07
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 2697 KLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAEC 2756
+L L+DEK RW+E+V+ L+ +GD++VA+G +AY G F YR L W+ +
Sbjct: 3211 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3270
Query: 2757 SELEIPSSN 2765
+P ++
Sbjct: 3271 RSHNVPHTS 3279
>AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy chain 7
protein.
Length = 4024
Score = 1281 bits (3173), Expect = 0.0
Identities = 723/1860 (38%), Positives = 1046/1860 (56%), Gaps = 97/1860 (5%)
Query: 979 TTDIVAMLSPEGERVNLGKGL---KARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE 1035
T DI M S EGE V L + + KARG VE WL ++E M S+ + A Y E
Sbjct: 1111 TLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYE 1170
Query: 1036 RVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTR 1095
R++WV P Q VL VSQI W K V IP+ I L Y K C ++D+ L R
Sbjct: 1171 RINWVRDWPGQTVLCVSQIFWTKEVQTA----IPMGIKA-LEQYLKTCNRQIDDIVTLVR 1225
Query: 1096 KDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARM 1155
L++ R L AL+ +DVHARD +S +V+K++ +DFEWL +RYYW+E+ + +M
Sbjct: 1226 GKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQEN--HLETKM 1283
Query: 1156 SSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAK 1215
+A YG+EYLG LVITPLTDRCY L GAL L L DLAK
Sbjct: 1284 INAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAK 1343
Query: 1216 SLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA 1275
++A QCVVFNCS+GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++TI+
Sbjct: 1344 AVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRG 1403
Query: 1276 KVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAE 1335
A MFEG E+KL TCA FITMNPGYAGR+ELPDNLKALFR ++MMVPDYA+IAE
Sbjct: 1404 INAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAE 1463
Query: 1336 VILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQH 1395
++LYS GF +++ L+ K+V Y+L SEQLS Q HYD+GMRAVKSVL AG LK P+++
Sbjct: 1464 IVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNEN 1523
Query: 1396 EEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQ 1455
EE+ LL ++ D NLPKFL+ D LF GI SDLFPGV LP DY + IK LQ
Sbjct: 1524 EEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQ 1583
Query: 1456 IEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVR 1515
+ K++Q++E MIVR G M+VG GGKT VL + E G+ + V+
Sbjct: 1584 MTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGL--MEENKVQ 1641
Query: 1516 KYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIE 1575
++NPKS+T+G+LYG+ + + EW DG+L + R + PD +WLI DGPVDAVWIE
Sbjct: 1642 ITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIE 1701
Query: 1576 NMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLP 1635
NMNTVLDDNK LCL + E I+++P ++++FE DL ASPATVSRCGM+Y++P+ +G+ P
Sbjct: 1702 NMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRP 1761
Query: 1636 FVRSWLQEGVEKNLFNQENSDFIYELF-KMTQVGLDHVNYNCGVGIKQVDISKVSAQCFL 1694
+ SW+ + + +FI LF +M V ++ + + D + V + L
Sbjct: 1762 LMLSWV--NLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNL 1819
Query: 1695 LGALLAEPGDRFADKAALK--------IYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKR 1746
+ + D FAD+ LK + F+F +W +G + + +R F ++++
Sbjct: 1820 IDCFM----DDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILR- 1874
Query: 1747 QFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPE--FIYDCN---------KP--- 1792
E E+ + N F + T Q K PE IYD +P
Sbjct: 1875 ---ELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIK 1931
Query: 1793 -------------FFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILN 1839
F E +VPT+DT+RY L E L KP +F G TG GK+ L
Sbjct: 1932 KLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLL 1991
Query: 1840 RMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKL 1899
Y P+++NFSAQT++ +TQ ++ +LDKR + G PLGK++++F+DDVNMP
Sbjct: 1992 NQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAR 2051
Query: 1900 DVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFA 1959
+VYGAQP IELLRQ+LD YD ++D+ + C+ PPGGGRNP+T R++RHF
Sbjct: 2052 EVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFN 2111
Query: 1960 MLYIAAPNADAMKTIFKAILKGHME---DFVPEVSVLGESIVNAAVEVYLKICAELLPTP 2016
++ I + +M TIF IL H+E F E L IVN + +Y + LLPTP
Sbjct: 2112 IITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTP 2171
Query: 2017 AKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKS---- 2072
AKSHY+FNLRD S+ +QGV ++ + + + RL+ HE LRV++DRL++ D+S
Sbjct: 2172 AKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLIN 2231
Query: 2073 YFYHLMASVCEKNFQTPI--LSVPDEPIIEHPPL--LLFGDFLNSSVPKENRTYQEIPDI 2128
Y ++ + ++F L ++ ++E L L+F DF + +E+ Y+EI D+
Sbjct: 2232 YIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPK--REDTNYREIADV 2289
Query: 2129 SKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRS 2188
L ++++ +L+EYN+ ++ M+LVLF+ H L+VG GGSGR+S
Sbjct: 2290 DNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQS 2349
Query: 2189 VATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFL 2248
V LA H+ + +E+ + YDT E+H+DL+++ + VFLFTDTQI +E FL
Sbjct: 2350 VTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFL 2409
Query: 2249 EDINNLLNSGEVPNLFEGDSYEQVQTGCR-TEAAKSGVNPSDRDGVYYF--FINRVRGKL 2305
ED++NLLN+GE+PNLF D +++ R + + +D + F FI+ R +L
Sbjct: 2410 EDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQL 2469
Query: 2306 HLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLG-NQEIITK 2364
H+ + MSP+G+AFR R R FP+LVNCCTIDWF WP +AL +VA + L+ + ++EI
Sbjct: 2470 HVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDG 2529
Query: 2365 ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRIS 2424
+C + H + ++ ++E++RY Y TP+S +++ + R
Sbjct: 2530 CIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYE 2589
Query: 2425 CGLQKLYETYDVVGVMEQQVREMEP---ILARKAAESIALVERLKIEQKAADEVKQAVMX 2481
GL+KL V M+ ++ + P + +++ E + ++E+ +E +++ V
Sbjct: 2590 VGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKI---VKA 2646
Query: 2482 XXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRF 2541
LA A+P +E DI +K+ + PPA V+
Sbjct: 2647 DETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKL 2706
Query: 2542 VMEPVCILMGVKPD---------------WDSTKKLLADVNFIGKLADYDKDHIPDATLK 2586
VME +CIL G+K D W K+LL D+ F+ L +YDKD+IP A +
Sbjct: 2707 VMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMN 2766
Query: 2587 KI-KVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKS 2645
I K Y+ + DF P+ + S + WV A+D Y KV ++V PK +K A LK
Sbjct: 2767 IIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKI 2826
Query: 2646 VMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADE 2705
M LR KQ ++ ++ +LA++ D L+ + ++ L+ VDL + +L RA +L L E
Sbjct: 2827 AMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGE 2886
Query: 2706 KTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIPSSN 2765
KTRW + Q TGDI+++SG +AY GAF S YR+ +W C +IP S+
Sbjct: 2887 KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSD 2946
Score = 252 bits (617), Expect = 1e-65
Identities = 133/420 (31%), Positives = 233/420 (55%), Gaps = 6/420 (1%)
Query: 539 YDEKSDLEKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQL 598
+ + D+++ ++ L KL + + +Q ++ F P+ Q + + +
Sbjct: 709 FGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLR 768
Query: 599 LWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSN----TIVPKCK 654
L++ + E++ +++W + P++ ++ D+++ +Y + +L+K + + K +
Sbjct: 769 LYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR 828
Query: 655 ELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDEL 714
++ K+ +P+I + NP L+PRHW + I+ P + F ++ + D
Sbjct: 829 SKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRF 888
Query: 715 MEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHI 774
++ AS E LE ++K+ W A+EF + +++ ++L +DEIQ LD+ I
Sbjct: 889 EGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRET-GTFILASVDEIQMLLDDHIIKT 947
Query: 775 STILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSAPDIQRQLPNET 834
T+ S P + ++ EW L L + L+EW Q TW+YLE IFS+PDI Q+P E
Sbjct: 948 QTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEG 1007
Query: 835 RLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVA 894
R F+ VDK+W+DIMR + + + T ++ E ++NE+L+ I+K L YLE KR+
Sbjct: 1008 RRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLF 1067
Query: 895 FPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFGVKFPESEMEIAEDGTLVE 954
FPRFFFLSNDELLEIL++T++P VQPHL+KCF+ IAK+EF + M+ +E G +VE
Sbjct: 1068 FPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSE-GEVVE 1126
>AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein.
Length = 4031
Score = 1281 bits (3173), Expect = 0.0
Identities = 723/1860 (38%), Positives = 1046/1860 (56%), Gaps = 97/1860 (5%)
Query: 979 TTDIVAMLSPEGERVNLGKGL---KARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE 1035
T DI M S EGE V L + + KARG VE WL ++E M S+ + A Y E
Sbjct: 1118 TLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYE 1177
Query: 1036 RVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTR 1095
R++WV P Q VL VSQI W K V IP+ I L Y K C ++D+ L R
Sbjct: 1178 RINWVRDWPGQTVLCVSQIFWTKEVQTA----IPMGIKA-LEQYLKTCNRQIDDIVTLVR 1232
Query: 1096 KDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARM 1155
L++ R L AL+ +DVHARD +S +V+K++ +DFEWL +RYYW+E+ + +M
Sbjct: 1233 GKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQEN--HLETKM 1290
Query: 1156 SSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAK 1215
+A YG+EYLG LVITPLTDRCY L GAL L L DLAK
Sbjct: 1291 INAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAK 1350
Query: 1216 SLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA 1275
++A QCVVFNCS+GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++TI+
Sbjct: 1351 AVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRG 1410
Query: 1276 KVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAE 1335
A MFEG E+KL TCA FITMNPGYAGR+ELPDNLKALFR ++MMVPDYA+IAE
Sbjct: 1411 INAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAE 1470
Query: 1336 VILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQH 1395
++LYS GF +++ L+ K+V Y+L SEQLS Q HYD+GMRAVKSVL AG LK P+++
Sbjct: 1471 IVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNEN 1530
Query: 1396 EEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQ 1455
EE+ LL ++ D NLPKFL+ D LF GI SDLFPGV LP DY + IK LQ
Sbjct: 1531 EEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQ 1590
Query: 1456 IEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVR 1515
+ K++Q++E MIVR G M+VG GGKT VL + E G+ + V+
Sbjct: 1591 MTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGL--MEENKVQ 1648
Query: 1516 KYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIE 1575
++NPKS+T+G+LYG+ + + EW DG+L + R + PD +WLI DGPVDAVWIE
Sbjct: 1649 ITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIE 1708
Query: 1576 NMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLP 1635
NMNTVLDDNK LCL + E I+++P ++++FE DL ASPATVSRCGM+Y++P+ +G+ P
Sbjct: 1709 NMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRP 1768
Query: 1636 FVRSWLQEGVEKNLFNQENSDFIYELF-KMTQVGLDHVNYNCGVGIKQVDISKVSAQCFL 1694
+ SW+ + + +FI LF +M V ++ + + D + V + L
Sbjct: 1769 LMLSWV--NLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNL 1826
Query: 1695 LGALLAEPGDRFADKAALK--------IYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKR 1746
+ + D FAD+ LK + F+F +W +G + + +R F ++++
Sbjct: 1827 IDCFM----DDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILR- 1881
Query: 1747 QFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPE--FIYDCN---------KP--- 1792
E E+ + N F + T Q K PE IYD +P
Sbjct: 1882 ---ELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIK 1938
Query: 1793 -------------FFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILN 1839
F E +VPT+DT+RY L E L KP +F G TG GK+ L
Sbjct: 1939 KLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLL 1998
Query: 1840 RMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKL 1899
Y P+++NFSAQT++ +TQ ++ +LDKR + G PLGK++++F+DDVNMP
Sbjct: 1999 NQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAR 2058
Query: 1900 DVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFA 1959
+VYGAQP IELLRQ+LD YD ++D+ + C+ PPGGGRNP+T R++RHF
Sbjct: 2059 EVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFN 2118
Query: 1960 MLYIAAPNADAMKTIFKAILKGHME---DFVPEVSVLGESIVNAAVEVYLKICAELLPTP 2016
++ I + +M TIF IL H+E F E L IVN + +Y + LLPTP
Sbjct: 2119 IITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTP 2178
Query: 2017 AKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKS---- 2072
AKSHY+FNLRD S+ +QGV ++ + + + RL+ HE LRV++DRL++ D+S
Sbjct: 2179 AKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLIN 2238
Query: 2073 YFYHLMASVCEKNFQTPI--LSVPDEPIIEHPPL--LLFGDFLNSSVPKENRTYQEIPDI 2128
Y ++ + ++F L ++ ++E L L+F DF + +E+ Y+EI D+
Sbjct: 2239 YIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPK--REDTNYREIADV 2296
Query: 2129 SKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRS 2188
L ++++ +L+EYN+ ++ M+LVLF+ H L+VG GGSGR+S
Sbjct: 2297 DNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQS 2356
Query: 2189 VATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFL 2248
V LA H+ + +E+ + YDT E+H+DL+++ + VFLFTDTQI +E FL
Sbjct: 2357 VTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFL 2416
Query: 2249 EDINNLLNSGEVPNLFEGDSYEQVQTGCR-TEAAKSGVNPSDRDGVYYF--FINRVRGKL 2305
ED++NLLN+GE+PNLF D +++ R + + +D + F FI+ R +L
Sbjct: 2417 EDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQL 2476
Query: 2306 HLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLG-NQEIITK 2364
H+ + MSP+G+AFR R R FP+LVNCCTIDWF WP +AL +VA + L+ + ++EI
Sbjct: 2477 HVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDG 2536
Query: 2365 ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRIS 2424
+C + H + ++ ++E++RY Y TP+S +++ + R
Sbjct: 2537 CIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYE 2596
Query: 2425 CGLQKLYETYDVVGVMEQQVREMEP---ILARKAAESIALVERLKIEQKAADEVKQAVMX 2481
GL+KL V M+ ++ + P + +++ E + ++E+ +E +++ V
Sbjct: 2597 VGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKI---VKA 2653
Query: 2482 XXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRF 2541
LA A+P +E DI +K+ + PPA V+
Sbjct: 2654 DETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKL 2713
Query: 2542 VMEPVCILMGVKPD---------------WDSTKKLLADVNFIGKLADYDKDHIPDATLK 2586
VME +CIL G+K D W K+LL D+ F+ L +YDKD+IP A +
Sbjct: 2714 VMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMN 2773
Query: 2587 KI-KVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKS 2645
I K Y+ + DF P+ + S + WV A+D Y KV ++V PK +K A LK
Sbjct: 2774 IIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKI 2833
Query: 2646 VMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADE 2705
M LR KQ ++ ++ +LA++ D L+ + ++ L+ VDL + +L RA +L L E
Sbjct: 2834 AMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGE 2893
Query: 2706 KTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIPSSN 2765
KTRW + Q TGDI+++SG +AY GAF S YR+ +W C +IP S+
Sbjct: 2894 KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSD 2953
Score = 250 bits (612), Expect = 5e-65
Identities = 132/420 (31%), Positives = 232/420 (55%), Gaps = 6/420 (1%)
Query: 539 YDEKSDLEKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQL 598
+ + D+++ ++ L KL + + +Q ++ F P+ Q + + +
Sbjct: 716 FGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLR 775
Query: 599 LWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSN----TIVPKCK 654
L++ + E++ +++W + P++ ++ D+++ +Y + +L+K + + K +
Sbjct: 776 LYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR 835
Query: 655 ELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDEL 714
++ K+ +P+I + NP L+PRHW + I+ P + F ++ + D
Sbjct: 836 SKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRF 895
Query: 715 MEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHI 774
++ AS E LE ++K+ W A+EF + +++ ++L +DEIQ LD+ I
Sbjct: 896 EGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRET-GTFILASVDEIQMLLDDHIIKT 954
Query: 775 STILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSAPDIQRQLPNET 834
T+ S P + ++ EW L L + L+EW Q TW+YLE IFS+PDI Q+P E
Sbjct: 955 QTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEG 1014
Query: 835 RLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVA 894
R F+ VDK+W+D MR + + + T ++ E ++NE+L+ I+K L YLE KR+
Sbjct: 1015 RRFTAVDKTWRDTMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLF 1074
Query: 895 FPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFGVKFPESEMEIAEDGTLVE 954
FPRFFFLSNDELLEIL++T++P VQPHL+KCF+ IAK+EF + M+ +E G +VE
Sbjct: 1075 FPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSE-GEVVE 1133
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 1278 bits (3167), Expect = 0.0
Identities = 691/1815 (38%), Positives = 1045/1815 (57%), Gaps = 47/1815 (2%)
Query: 968 KLAKTASPEDLTTDIVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMK-- 1025
++ K P + V M S +GE ++ + G VE WLG VE+ M +++ ++
Sbjct: 1607 RIQKVGGPSS-KWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNC 1665
Query: 1026 -FALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKC- 1083
AL++++ N+R WV+ QVV+T SQI W V + L R D +L KK
Sbjct: 1666 HLALRKFL-NKRDKWVKEWAGQVVITASQIQWTADVTKCL-LTAKERADKKILKVMKKNQ 1723
Query: 1084 ISDLNDLAALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYY 1143
+S LN + R +LT + R + AL+TI++HARD + + + + N F+WL +R+Y
Sbjct: 1724 VSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFY 1783
Query: 1144 WEEDIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXX 1203
WE+D+D+CV R ++ + Y +EYLG G LVITPLTDRCY+ L AL L
Sbjct: 1784 WEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAG 1843
Query: 1204 XXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLS 1263
DL K+L I +V NCSEGLDYK MGR +SGLA +GAW CFDEFNRI+IEVLS
Sbjct: 1844 TGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLS 1903
Query: 1264 VIAQQLITIRNAKVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPI 1323
V+A Q++ I +A A T F F+G EI LV +C FITMNPGYAGRTELP+NLK++FRPI
Sbjct: 1904 VVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPI 1963
Query: 1324 SMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVM 1383
+M+VPD LIAE+IL+ EGF + K LAKK+ +Y L+ +QLS+QDHYDFG+RA+ S+L
Sbjct: 1964 AMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRY 2023
Query: 1384 AGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED 1443
AG +R PD +E LL ++ D N+ K + DA LF I+ DLFP + LP DYG + +
Sbjct: 2024 AGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRE 2083
Query: 1444 VIKIIMLERKLQIEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYE 1503
++ + + LQ + KV QL+ET R M+VG TG GKT +L + + L
Sbjct: 2084 TVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCR 2143
Query: 1504 NGVEGSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWL 1563
G + VR++ +NPK+L++GELYGE +L T EW DGIL +RTA PD +W+
Sbjct: 2144 AG--DPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWI 2201
Query: 1564 ICDGPVDAVWIENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGM 1623
+ DGPVD +WIENMN+V+DDNK+L L N ERI + V ++FEV DLA ASPATVSRCGM
Sbjct: 2202 LFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGM 2261
Query: 1624 VYIDPNEMGYLPFVRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQV 1683
VY D ++G+ P+V+SWL++ + + E ++E K+ L NC +
Sbjct: 2262 VYTDYADLGWKPYVQSWLEKRPKAEV---EPLQRMFE--KLINKMLAFKKDNCKELVPLP 2316
Query: 1684 DISKVSAQCFLLGALLA-EPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEE 1742
+ S +++ C L AL E G AD + F+F +W + ++ E R+ +
Sbjct: 2317 EYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDS 2376
Query: 1743 VIKRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPE-FIYDCNKPFFETLVPTI 1801
++ E E + +P ++ ++D + R + + +P+ + Y N PF++ +VPT+
Sbjct: 2377 YLR----EIEGS--FPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTV 2430
Query: 1802 DTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSP 1861
DTVRY YL L+ P++ G G GKT IA +L + + + V +++N SAQT+S
Sbjct: 2431 DTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSV-LVVNMSAQTTSN 2489
Query: 1862 RTQEVIELRLDKRPRKAIGAPL-GKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGV 1920
Q +IE R++KR K + P GK +I F+DD+NMP D++G+QP +EL+R ++D+G
Sbjct: 2490 NVQSIIESRVEKR-TKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFW 2548
Query: 1921 YDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILK 1980
YDR K K I ++ L + PPGGGR ++ R F ++ + P + IF ++
Sbjct: 2549 YDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMIN 2608
Query: 1981 GHMEDFVPEVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQA 2040
++DF EV +G + A +++Y + LPTP K HY+FNLRD+SK QG+L+A
Sbjct: 2609 QKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANK 2668
Query: 2041 AYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIE 2100
+ + + RL+ HEC RVF DRL++ D F +++ F + +
Sbjct: 2669 DFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPS---K 2725
Query: 2101 HPPLLLFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYN-STARAEMHLVLFQDXX 2159
PP +FGDFL KE + Y+++ D++ L V++ L+EYN S + M LVLF++
Sbjct: 2726 RPP--IFGDFL-----KEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAI 2778
Query: 2160 XXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDL 2219
G+ L+VG GGSGR+S+A LA + + +E+ ++Y EF DD+
Sbjct: 2779 EHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDI 2838
Query: 2220 RMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTE 2279
+ +Y +AGV + T F+F DTQI E FLEDINN+L+SGEVPNL++ D +E++Q+ +
Sbjct: 2839 KRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQ 2898
Query: 2280 AAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTK 2339
A V P D ++ + I RV+ LH+ +C+SP+G+ FR R +P+LVNC TI+WF++
Sbjct: 2899 ARVEQV-PESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSE 2957
Query: 2340 WPPEALLSVAHQCL--QPLGNQE-IITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPS 2396
WP EALL VA +CL LG QE I K++++ VTMH +V + ++ +E+RR+ Y TP+
Sbjct: 2958 WPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPT 3017
Query: 2397 SXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAA 2456
++ +++ GL K+ ET + V VM ++ + + +A
Sbjct: 3018 KYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQK 3077
Query: 2457 ESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXX 2516
+ + + +++ ADE ++AV L A+PA+E
Sbjct: 3078 QCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMR 3137
Query: 2517 XXXXXXXXDINELKAFQKPPALVRFVMEPVCILMGVKPDWDSTKKLLADVNFIGKLADYD 2576
DI E+K++ +PPA V VM+ V IL G +P W K+ L + NFI L ++D
Sbjct: 3138 ALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFD 3197
Query: 2577 KDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKH 2636
KD+I D LKKI Y DF PD + +VS +S+ +WV+A+++Y +++RVVEPK ++
Sbjct: 3198 KDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRM 3257
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQ---LAKMMDELKTVEDERLKLQADVDLAAARLS 2693
A A L+ A L Q+++ + + L K DE ++E K +++L +L
Sbjct: 3258 NAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMEL---KLE 3314
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELK-W 2752
RAG L LA EK RWEE+V+ + L GD ++A+ ++Y G F ++YR E+ + W
Sbjct: 3315 RAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIW 3374
Query: 2753 IAECSELEIPSSNTF 2767
I + EL++P S +F
Sbjct: 3375 IGKIWELQVPCSPSF 3389
Score = 244 bits (598), Expect = 3e-63
Identities = 134/404 (33%), Positives = 216/404 (53%), Gaps = 8/404 (1%)
Query: 549 METLDDLLE---KLMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKE 605
M LD + + LMA + +R IFKI + L ++ Q +W+ +++
Sbjct: 1217 MSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARD 1276
Query: 606 WNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSNT--IVPKCKELIDVIKEK 663
W + + W F L + ++ T + +L K I+ + I+ K
Sbjct: 1277 WEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRT 1336
Query: 664 LPVISYLRNPALKPRHWVKIEEILHTRFTPDVV-MNLQMFEELQAFQHSDELMEVAGQAS 722
+P+IS LRNPAL+ RHW ++ + + F + L+ EL QH +++ E++ A+
Sbjct: 1337 MPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASAT 1396
Query: 723 SEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSSRN 782
E +E L+ + + W + ++ +KD + + L G +E+ +L+++ + +ST+ +SR
Sbjct: 1397 KELAIEVALQNIAKTWDVTQLDIVPYKD-KGHHRLRGTEEVFQALEDNQVALSTMKASRF 1455
Query: 783 CGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSAPDIQRQLPNETRLFSIVDK 842
+ V+ W + L L + +E Q+ WMYLE IF DI++QLPNE+ LF V+
Sbjct: 1456 VKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNS 1515
Query: 843 SWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLS 902
+WK IM ++ K A+ + P L + + N +L+ I K L+ YLETKR FPRF+FLS
Sbjct: 1516 NWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLS 1575
Query: 903 NDELLEILAQTRNPHAVQPHLRKCFDAIAKLEF-GVKFPESEME 945
ND+LLEIL Q+RNP AVQPHL+KCFD I L V P S+ E
Sbjct: 1576 NDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWE 1619
>AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dynein
type 3 protein.
Length = 4116
Score = 1263 bits (3130), Expect = 0.0
Identities = 699/1845 (37%), Positives = 1043/1845 (56%), Gaps = 79/1845 (4%)
Query: 981 DIVAMLSPEGERVNLGKGL---KARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNERV 1037
+IV M+S E E V + + A+G VE WL +VE+ M AS++ + ++ Y+ R
Sbjct: 1216 EIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRN 1275
Query: 1038 DWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKD 1097
WV P QVV+ VS I W + V + + LL + KK + + L R
Sbjct: 1276 HWVLQWPGQVVICVSSIFWTQEVSQAL-------AENTLLDFLKKSNDQIAQIVQLVRGK 1328
Query: 1098 LTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYW-EEDIDNCVARMS 1156
L+ R L AL IDVHARD ++ + E V NDF+W+ +RYYW +D+ ++
Sbjct: 1329 LSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQ---VQII 1385
Query: 1157 SAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKS 1216
+ +YG+EYLG LVITPLTDRCY LMGAL+L+L DLAK+
Sbjct: 1386 TTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKA 1445
Query: 1217 LAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAK 1276
LA QCVVFNCS+GLDYK MG+FF GLA +GAW CFDEFNRI++EVLSV+AQQ+++I+ A
Sbjct: 1446 LAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAI 1505
Query: 1277 VAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEV 1336
+ K F+FEG E+ L TCA FITMNPGYAGR ELPDNLKALFR ++MMVPDYALI E+
Sbjct: 1506 IRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEI 1565
Query: 1337 ILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHE 1396
LYS GF S+ LA+K+V Y+L SEQLS Q HYD+GMRAVKSVL AG LK P+++E
Sbjct: 1566 SLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENE 1625
Query: 1397 EMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQI 1456
+ LL AL D NL KFLA D LF GI+SDLFPGV LP DY V V+ + + KLQ
Sbjct: 1626 SVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQP 1685
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
I K+IQ++E M+VR G M+VG GGKT VL L+ + V
Sbjct: 1686 VPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLH--AANQMEEFAVEY 1743
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
I+NPK++T+G+LYG + + EW DG+L R L+ D +W+I DGPVDA+WIEN
Sbjct: 1744 KIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIEN 1803
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
MNTVLDDNK LCL + E I++ + ++FE ADL QASPATVSRCGM+Y++P+++G+ P
Sbjct: 1804 MNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPL 1863
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFK-MTQVGLDHVNYNCGVGIKQVDISKVSAQCFLL 1695
S++ + + +L +E+ + + ++F + Q L+ +C ++ I + L
Sbjct: 1864 KDSYM-DTLPSSL-TKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLY 1921
Query: 1696 GALL----------AEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIK 1745
+LL E G+ + + +++ F+F VW + G I +R+ F+ +
Sbjct: 1922 SSLLDEIRAVEEEEMELGEGLSSQQIF-LWLQGLFLFSLVWTVAGTINADSRKKFDVFFR 1980
Query: 1746 RQFEEYEEAE------------YYPQGFNFFDMY-MDTRQRKLKVWAEIIP--EFIYDCN 1790
++ +P+ + +D Y + + W + I E
Sbjct: 1981 NLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAG 2040
Query: 1791 KPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPV 1850
E ++PT++T R + + L P++F G TG GK+ I L + Y+P
Sbjct: 2041 AKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLP-KNTYLPN 2099
Query: 1851 ILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIEL 1910
+NFSA+TS+ +TQ++I +LD+R + G P+GKK ++F+DD+NMP +VYGAQP IEL
Sbjct: 2100 CINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIEL 2159
Query: 1911 LRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADA 1970
LRQ++D G +D+ DI+D++L + PPGGGRN +T RF RH ++ I A D
Sbjct: 2160 LRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDI 2219
Query: 1971 MKTIFKAILKGHM-EDFVPEVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLS 2029
+ IF +I+ H + F G+ +V A +Y LPTP+KSHYVFNLRD S
Sbjct: 2220 LTKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFS 2279
Query: 2030 KSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTP 2089
+ +QGVL +++ + +RL+ HE RVF+DRLI+ +D+ F++++ F+
Sbjct: 2280 RVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQT 2339
Query: 2090 I------LSVPDEPIIEHPPLLLFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYN 2143
I LS + + ++ L FGD+ + + Y EI D+ +L +V++ YL+E+N
Sbjct: 2340 IEKVLIHLSPTGKIVDDNIRSLFFGDYFKPE--SDQKIYDEITDLKQLTVVMEHYLEEFN 2397
Query: 2144 STARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLG 2203
+ ++A M LV+F+ GH L+VG GGSGR+S A L+ +N +
Sbjct: 2398 NISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQ 2457
Query: 2204 MELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNL 2263
+E+ +NY ++ +DL+ + ++ GV + TVFLF D QI E F+EDIN LLN+G+VPN+
Sbjct: 2458 IEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNI 2517
Query: 2264 F----EGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFR 2319
F + D E++QT RT+ K V P +Y FFI RV K+ + MSP+G+AFR
Sbjct: 2518 FPADEKADIVEKMQTAARTQGEKVEVTPL---SMYNFFIERVINKISFSLAMSPIGDAFR 2574
Query: 2320 RRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLG-NQEIITKISKLCVTMHQNVDM 2378
R RMFPSL+NCCTIDWF WP +AL VA++ L+ + + I ++ +C ++V
Sbjct: 2575 NRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESVKK 2634
Query: 2379 MTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVG 2438
++ Y ++RR+ Y TP+S + R+R GLQKL V
Sbjct: 2635 LSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVA 2694
Query: 2439 VMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXX 2498
VM++++ ++P L + E+ ++ +++ E + AD K V
Sbjct: 2695 VMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKN 2754
Query: 2499 XXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILMGVKPD--- 2555
LA AMPA+E DI+ +K+ Q PP V+ VME +CI+ G+KP+
Sbjct: 2755 ECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKP 2814
Query: 2556 ------------WDSTKKLLADVNFIGKLADYDKDHIPDATLKKIKV-YLTHKDFNPDTV 2602
W +KK+L D+ F+ L YDKD+IP T+K+I+ ++ H +F P +
Sbjct: 2815 DPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVI 2874
Query: 2603 VKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEA 2662
VS C + WV+A+++Y +V +VV PK + +EA L + M L K+ E++ +
Sbjct: 2875 KNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVD 2934
Query: 2663 QLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHC 2722
+L + D+ + + ++ L+ ++++ + +L RA KL L EK RW E+ + +
Sbjct: 2935 RLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTN 2994
Query: 2723 TTGDIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIPSSNTF 2767
TGD++++SG +AY GAF YR + + +W+AEC + IP + F
Sbjct: 2995 LTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDF 3039
Score = 238 bits (583), Expect = 2e-61
Identities = 171/621 (27%), Positives = 284/621 (45%), Gaps = 22/621 (3%)
Query: 322 FLNRMQAFMDSFKEAHEMDVN-IIKQERDLNEFRKLCEKFVKQMEAIEDVVSYQPLGLIF 380
+LN + ++D E ++ +K+ D+++F K+ I + PL +
Sbjct: 606 YLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFC 665
Query: 381 LCLSPFQELFRPQPKRLFDVVLNVTPDIGRECIDGILEGVENISGDITKDPETASELVAF 440
L + + + L D ++ D+ R+ I +I+ +++ P ELV+
Sbjct: 666 LDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSL 725
Query: 441 NFMLDGLESRVAFXXXXXXXXXXXX--DLMGEFNIPIPPEDMTQFLGLSVTLSTLRSDVD 498
L + F LM ++P ED+ F L R +
Sbjct: 726 IEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDI--FDNSRNLLLHKRDQAE 783
Query: 499 ARIESRSKLAGMFASQIGKDIMNLMLDVNKLRDEVTQPWLYDEKSDLEKVMETLDDLLEK 558
+ R ++ + + L+ + R+ +T + K ++EK L++L +
Sbjct: 784 MDLIKRCS-----EFELRLEGYHRELESFRKREVMTTE---EMKHNVEK----LNELSKN 831
Query: 559 LMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPF 618
L A + I + +++ + + L + + + LW + E++ + W + P
Sbjct: 832 LNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPL 891
Query: 619 NTLDVD----EIQNTTISYGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPA 674
L+ + EI N + K+ L + K ID K+ +P++S NP
Sbjct: 892 FLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPG 951
Query: 675 LKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKV 734
+K RHW +I EI+ P L E + ++L + AS E LE L ++
Sbjct: 952 MKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRM 1011
Query: 735 EEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKSRVEEWA 794
+ W + F + ++D D +L +D+IQ LD+ I T+ S PI++ +W
Sbjct: 1012 KLDWVNVTFSFVKYRDT-DTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWE 1070
Query: 795 KNLELFAKTLEEWYACQQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKV 854
+ L L+ W CQ TW+YLE IFS+ DI Q+P E R F IVD WK +M + K
Sbjct: 1071 EKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKD 1130
Query: 855 PLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTR 914
+ AA QP++ E+ N +L+ I K L YLE KR+ FPRFFFLSNDELLEIL++T+
Sbjct: 1131 NRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETK 1190
Query: 915 NPHAVQPHLRKCFDAIAKLEF 935
+P VQPHL+KCF+ IAKLEF
Sbjct: 1191 DPLRVQPHLKKCFEGIAKLEF 1211
>AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein.
Length = 2536
Score = 1163 bits (2880), Expect = 0.0
Identities = 651/1682 (38%), Positives = 948/1682 (56%), Gaps = 87/1682 (5%)
Query: 1154 RMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDL 1213
+M +A YG+EYLG LVITPLTDRCY L GAL L L DL
Sbjct: 7 KMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDL 66
Query: 1214 AKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIR 1273
AK++A QCVVFNCS+GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++TI+
Sbjct: 67 AKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQ 126
Query: 1274 NAKVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALI 1333
A MFEG E+KL TCA FITMNPGYAGR+ELPDNLKALFR ++MMVPDYA+I
Sbjct: 127 RGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMI 186
Query: 1334 AEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPD 1393
AE++LYS GF +++ L+ K+V Y+L SEQLS Q HYD+GMRAVKSVL AG LK P+
Sbjct: 187 AEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPN 246
Query: 1394 QHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERK 1453
++EE+ LL ++ D NLPKFL+ D LF GI SDLFPGV LP DY + IK
Sbjct: 247 ENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMN 306
Query: 1454 LQIEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQP 1513
LQ+ K++Q++E MIVR G M+VG GGKT VL + E G+ +
Sbjct: 307 LQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGL--MEENK 364
Query: 1514 VRKYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVW 1573
V+ ++NPKS+T+G+LYG+ + + EW DG+L + R + PD +WLI DGPVDAVW
Sbjct: 365 VQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVW 424
Query: 1574 IENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGY 1633
IENMNTVLDDNK LCL + E I+++P ++++FE DL ASPATVSRCGM+Y++P+ +G+
Sbjct: 425 IENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGW 484
Query: 1634 LPFVRSWLQEGVEKNLFNQENSDFIYELF-KMTQVGLDHVNYNCGVGIKQVDISKVSAQC 1692
P + SW+ + + +FI LF +M V ++ + + D + V +
Sbjct: 485 RPLMLSWVN--LLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 542
Query: 1693 FLLGALLAEPGDRFADKAALK--------IYIAHCFIFCYVWCIGGNILEMNRQSFEEVI 1744
L+ + D FAD+ LK + F+F +W +G + + +R F +++
Sbjct: 543 NLIDCFM----DDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKIL 598
Query: 1745 KRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPE--FIYDCN---------KP- 1792
+ E E+ + N F + T Q K PE IYD +P
Sbjct: 599 R----ELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPW 654
Query: 1793 ---------------FFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEI 1837
F E +VPT+DT+RY L E L KP +F G TG GK+
Sbjct: 655 IKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNF 714
Query: 1838 LNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMP 1897
L Y P+++NFSAQT++ +TQ ++ +LDKR + G PLGK++++F+DDVNMP
Sbjct: 715 LLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMP 774
Query: 1898 KLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRH 1957
+VYGAQP IELLRQ+LD YD ++D+ + C+ PPGGGRNP+T R++RH
Sbjct: 775 AREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRH 834
Query: 1958 FAMLYIAAPNADAMKTIFKAILKGHME---DFVPEVSVLGESIVNAAVEVYLKICAELLP 2014
F ++ I + +M TIF IL H+E F E L IVN + +Y + LLP
Sbjct: 835 FNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLP 894
Query: 2015 TPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKS-- 2072
TPAKSHY+FNLRD S+ +QGV ++ + + + RL+ HE LRV++DRL++ D+S
Sbjct: 895 TPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWL 954
Query: 2073 --YFYHLMASVCEKNFQTPI--LSVPDEPIIEHPPL--LLFGDFLNSSVPKENRTYQEIP 2126
Y ++ + ++F L ++ ++E L L+F DF + +E+ Y+EI
Sbjct: 955 INYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPK--REDTNYREIA 1012
Query: 2127 DISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGR 2186
D+ L ++++ +L+EYN+ ++ M+LVLF+ H L+VG GGSGR
Sbjct: 1013 DVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGR 1072
Query: 2187 RSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEE 2246
+SV LA H+ + +E+ + YDT E+H+DL+++ + VFLFTDTQI +E
Sbjct: 1073 QSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEES 1132
Query: 2247 FLEDINNLLNSGEVPNLFEGDSYEQVQTGCR-TEAAKSGVNPSDRDGVYYF--FINRVRG 2303
FLED++NLLN+GE+PNLF D +++ R + + +D + F FI+ R
Sbjct: 1133 FLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRS 1192
Query: 2304 KLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLG-NQEII 2362
+LH+ + MSP+G+AFR R R FP+LVNCCTIDWF WP +AL +VA + L+ + ++EI
Sbjct: 1193 QLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIR 1252
Query: 2363 TKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDR 2422
+C + H + ++ ++E++RY Y TP+S +++ + R
Sbjct: 1253 DGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKR 1312
Query: 2423 ISCGLQKLYETYDVVGVMEQQVREMEP---ILARKAAESIALVERLKIEQKAADEVKQAV 2479
GL+KL V M+ ++ + P + +++ E + ++E+ +E +++ V
Sbjct: 1313 YEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKI---V 1369
Query: 2480 MXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALV 2539
LA A+P +E DI +K+ + PPA V
Sbjct: 1370 KADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGV 1429
Query: 2540 RFVMEPVCILMGVKPD---------------WDSTKKLLADVNFIGKLADYDKDHIPDAT 2584
+ VME +CIL G+K D W K+LL D+ F+ L +YDKD+IP A
Sbjct: 1430 KLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAY 1489
Query: 2585 LKKI-KVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAIL 2643
+ I K Y+ + DF P+ + S + WV A+D Y KV ++V PK +K A L
Sbjct: 1490 MNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGEL 1549
Query: 2644 KSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALA 2703
K M LR KQ ++ ++ +LA++ D L+ + ++ L+ VDL + +L RA +L L
Sbjct: 1550 KIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLG 1609
Query: 2704 DEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIPS 2763
EKTRW + Q TGDI+++SG +AY GAF S YR+ +W C +IP
Sbjct: 1610 GEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPC 1669
Query: 2764 SN 2765
S+
Sbjct: 1670 SD 1671
>AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein.
Length = 3051
Score = 1133 bits (2806), Expect = 0.0
Identities = 638/1804 (35%), Positives = 977/1804 (54%), Gaps = 42/1804 (2%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE-RVDWV 1040
+ AM+S EGE + K ++A G VEDW+ V M + + K A+ Y + RVDW+
Sbjct: 194 VSAMISAEGEVMEFRKIVRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWM 253
Query: 1041 EMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTL 1100
++ VVL SQ+ W V +VF+ + + +Y +K +++L L+
Sbjct: 254 LLYQGMVVLAASQVWWTWEVEDVFH-KAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSK 312
Query: 1101 LFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSAMY 1160
RK ++ IDVHARD + + + +A +F+W +R+YW+ + D R + +
Sbjct: 313 NDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTF 372
Query: 1161 IYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQ 1220
YG+EY+G G LVITPLTDR YL L AL + L DLAK+L +
Sbjct: 373 GYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLL 432
Query: 1221 CVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQ 1280
CVV NC EG+DY+ +G+ FSGLA GAW CFDEFNRID VLSVI+ Q+ TIRNA + +
Sbjct: 433 CVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQL 492
Query: 1281 TRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYS 1340
T F FEG+EI L FITMNPGYAGRTELP+++KALFRP+ ++VPD I E++L+S
Sbjct: 493 TTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFS 552
Query: 1341 EGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTL 1400
EGF +K LAKKM +YKL+ EQLSKQ HYDFG+RA+KSVLVMAG LKR + D E++ L
Sbjct: 553 EGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVL 612
Query: 1401 LCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQ 1460
+ AL D NLPKF+ D LF G++SDLFPG+ P Y D ++ ++ E + Q
Sbjct: 613 MRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQ 672
Query: 1461 IRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMN 1520
+ KV+Q+ ETM+ R M+VGPT GGK+VV++ L T+L G+ + YI+N
Sbjct: 673 VDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKL---GL------TTKLYILN 723
Query: 1521 PKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLN-PDHQWLICDGPVDAVWIENMNT 1579
PK++++ ELYG ++ T +W DG+L R + + + ++++ DG VDA+W+ENMN+
Sbjct: 724 PKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNS 783
Query: 1580 VLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRS 1639
V+DDN++L L+N ERI+L + ++FEV DL ASPATVSRCGMVY+DP + Y P+ +
Sbjct: 784 VMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKK 843
Query: 1640 WLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFL-LGAL 1698
W+ + N Q N + ++E K +D + G + + + Q L +
Sbjct: 844 WVNQ--IPNKVEQYNLNSLFE--KYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQ 899
Query: 1699 LAEPGDRFADKAALKIYIAHCFIFCYVWC-IGGNILEMNRQSFEEVIKR---------QF 1748
LA+ D + + + C+ ++C +G ++LE R F+E IKR +
Sbjct: 900 LAKMLDALLEGEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEG 959
Query: 1749 EEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPEFIYDCNKPFFETLVPTIDTVRYGY 1808
E Q +D + D ++ + W++++PE+I+ + F LV T+DT R +
Sbjct: 960 VWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTW 1019
Query: 1809 LFEKLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIE 1868
+ E+++ +PV+F G +G KT L +S V +++NFS++T+S Q +E
Sbjct: 1020 ILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETNIV-LMVNFSSRTTSMDIQRNLE 1078
Query: 1869 LRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDK-LY 1927
++KR + G P+GK++++F+DD+NMP++D YG Q I LL+ L+ G +YDR K L
Sbjct: 1079 ANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELN 1138
Query: 1928 WKDILDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFV 1987
K I D+ + GGGRN + RF+ F++ + P+ +++ I+ +ILKGH F
Sbjct: 1139 CKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFH 1198
Query: 1988 PEVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQ 2047
+ + + + +Y I +L PTP+K HY+FNLRDLS+ G++ ++
Sbjct: 1199 ESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVA 1258
Query: 2048 GMLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEHPPLLLF 2107
M+R++ +ECLRVFHDRLI+ DK + S+ ++F+ + V +PI LF
Sbjct: 1259 QMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVEHFKDDVEVVMRDPI-------LF 1311
Query: 2108 GDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXX 2167
GDF + E R Y++I D + +E L+EYN + +M+LVLF D
Sbjct: 1312 GDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNE-SNTKMNLVLFDDALEHLTRVHR 1370
Query: 2168 XXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAG 2227
GH L+VG GGSG++S++ LA C+ + L R Y F +DL+ +Y++ G
Sbjct: 1371 IIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLG 1430
Query: 2228 VNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNP 2287
+ + +FLFTD + +E FLE INN+L SG VP LF + E + + EA K G+ P
Sbjct: 1431 IENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGP 1490
Query: 2288 SDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLS 2347
+ ++ V+ +F+N+ LH+ + MSPVG+ R CR FP +VN IDWF WPP+AL +
Sbjct: 1491 A-KESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHA 1549
Query: 2348 VAHQCL--QPLGNQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXX 2405
VA L P+ E I + K V +HQ+VD + + ++RR Y TP +
Sbjct: 1550 VAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTY 1609
Query: 2406 XXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERL 2465
I R+ GL KL E + + Q++ E + +LA K+A AL+E +
Sbjct: 1610 SKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEI 1669
Query: 2466 KIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXD 2525
+ A+E K+ LA MP +E D
Sbjct: 1670 AVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSD 1729
Query: 2526 INELKAFQKPPALVRFVMEPVCILMGVKP-DWDSTKKLLADVNFIGKLADYDKDHIPDAT 2584
+ E+++F KPP V+ V E + I+ G K +W + K +++D NF+ L + D D I +
Sbjct: 1730 VTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQ 1789
Query: 2585 LKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILK 2644
+K IK L + + + VSK M+ +V+A+ Y VFR ++PK K
Sbjct: 1790 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFY 1849
Query: 2645 SVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALAD 2704
L Q E+ AI+ +L + + + E+ KLQ + ++ RL A KL L
Sbjct: 1850 LTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGS 1909
Query: 2705 EKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELK-WIAECSELEIPS 2763
E RW + + GD ++ + ++Y GAF +R E+ + W + E EIP
Sbjct: 1910 ENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPL 1969
Query: 2764 SNTF 2767
S F
Sbjct: 1970 SQPF 1973
Score = 149 bits (362), Expect = 1e-34
Identities = 76/181 (41%), Positives = 105/181 (58%), Gaps = 1/181 (0%)
Query: 755 YVLGGLDEIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTW 814
Y+LG +DEI SLD++ ++ +I SR GP V +W K L L + +E W Q+ W
Sbjct: 5 YILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKW 64
Query: 815 MYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNN 874
MYLE IF DI+ QLP E + F +DK +K IM + K P+ P + +
Sbjct: 65 MYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVS 124
Query: 875 EMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLE 934
E L++ K L YL++KR AFPRFFF+S+DELL IL + +P VQ H+ K +D IA L
Sbjct: 125 EGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDNIASLR 183
Query: 935 F 935
F
Sbjct: 184 F 184
>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain 9
protein.
Length = 4486
Score = 1053 bits (2608), Expect = 0.0
Identities = 628/1836 (34%), Positives = 957/1836 (52%), Gaps = 49/1836 (2%)
Query: 944 MEIAEDGTL---VEKEMSFQTRDMLQAKLAKTASPEDLTTDIVAMLSPEGERVNLGKGLK 1000
++I +GT V++ +S +M + + AS E T + M S E E V +
Sbjct: 1613 LDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSL-GMYSKEEEYVAFSEPCD 1671
Query: 1001 ARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGV 1060
G VE WL V M A+V+ M + Y R W+ HP QV LT +QI W V
Sbjct: 1672 CSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEV 1731
Query: 1061 HEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTLLFRKVLCALITIDVHARDTI 1120
F + ++ + Y KK ++ L L + L+ R+ + + TIDVHARD +
Sbjct: 1732 GMAF-ARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVV 1790
Query: 1121 SHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTD 1180
+ M+ + V A F WL +R+ W++++ +C A + A ++Y +EYLG LVITPLTD
Sbjct: 1791 AKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTD 1850
Query: 1181 RCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFS 1240
RCY+ L +L L + DL ++L I VFNCSE +DYK G +
Sbjct: 1851 RCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYK 1910
Query: 1241 GLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMFEGREIKLVRTCAAFI 1300
GLA +GAW CFDEFNRI +EVLSV+A Q+ +I++A K+ F F G EI L + FI
Sbjct: 1911 GLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFI 1970
Query: 1301 TMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLS 1360
TMNPGYAGRTELP+NLK+LFRP +M+VPD+ LI E++L +EGF ++ LA+K + +Y+L
Sbjct: 1971 TMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLC 2030
Query: 1361 SEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILF 1420
E LSKQDHYD+G+RA+KSVLV+AG+LKR +PD+ E+ L+ +L D N+PK + D +F
Sbjct: 2031 KELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIF 2090
Query: 1421 AGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVIQLHETMIVRWGVMLV 1480
G++ DLFP + +P R E +++ +++ KLQ E + KV+QL E + VR V +V
Sbjct: 2091 MGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVV 2150
Query: 1481 GPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEW 1540
G G GK+ VL L TY + + +PV +NPK++T EL+G +N T EW
Sbjct: 2151 GGAGTGKSQVLRSLHKTYQIM--------KRRPVWT-DLNPKAVTNDELFGIINPATGEW 2201
Query: 1541 HDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIENMNTVLDDNKMLCLSNSERIKLTPY 1600
DG+ +R + +W++ DG +D +WIE++NTV+DDNK+L L+++ERI L P
Sbjct: 2202 KDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPT 2261
Query: 1601 VHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRSWLQEGVEKNLFNQENSDFIYE 1660
+ ++FE++ L A+PATVSR G++YI+P ++G+ P V SW +EK E ++
Sbjct: 2262 MKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSW----IEKREIQTERANLTIL 2317
Query: 1661 LFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLGALLAEPGDRFADKAALKIYIAHCF 1720
K LD + I + S V C LL LL D AD +IY H F
Sbjct: 2318 FDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTE-DIPAD-CPKEIY-EHYF 2374
Query: 1721 IFCYVWCIGGNILEMNRQSFE-EVIKRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWA 1779
+F +W GG +++ + E K E++ ++ QG FD Y+D +K + W+
Sbjct: 2375 VFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQG-TIFDYYIDPETKKFEPWS 2433
Query: 1780 EIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILN 1839
+++P+F +D P LV T +T+R Y E+L+ +PVM G G GK+ + L
Sbjct: 2434 KLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLA 2493
Query: 1840 RMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKL 1899
+ Y V L F+ T+S Q V+E L+K+ + G P KK+I FIDD+NMP++
Sbjct: 2494 SLDPEAYLVK-NLPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEV 2552
Query: 1900 DVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFA 1959
D YG ++RQ LD+G YDR KL K+I +V SC P G + R RHF+
Sbjct: 2553 DAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQY-VSCMNPTAGSFTINPRLQRHFS 2611
Query: 1960 MLYIAAPNADAMKTIFKAILKGHME--DFVPEVSVLGESIVNAAVEVYLKICAELLPTPA 2017
+ ++ P ADA+ +I+ IL H++ +F + +++ A+ + KI LPT
Sbjct: 2612 VFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGI 2671
Query: 2018 KSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHL 2077
K HY+FNLRD + QG+L + ++S ++RL+ HE RV+ D+++ +D F +
Sbjct: 2672 KFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKI 2731
Query: 2078 MASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNS-SVPKENRTYQEIPDISKLMIVLK 2136
V +K F ++P+ + L+ F N PK Y + L L
Sbjct: 2732 QTEVLKKTFDD-----IEDPVEQTQSPNLYCHFANGIGEPK----YMPVQSWELLTQTLV 2782
Query: 2137 EYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHV 2196
E L+ +N M LVLF+D G+ L+VG GGSG++S+ LA +
Sbjct: 2783 EALENHNE-VNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFI 2841
Query: 2197 NECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLN 2256
+ + L++ Y +F DL + ++AGV +TVFL TD Q+ E FL IN+LL
Sbjct: 2842 SSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLA 2901
Query: 2257 SGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGE 2316
SGE+P+L+ D E + + R E G+ +R+ + FFI+R+R +L + +C SPVG
Sbjct: 2902 SGEIPDLYSDDEVENIISNVRNEVKSQGL-VDNRENCWKFFIDRIRRQLKVTLCFSPVGN 2960
Query: 2317 AFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQEIITK--ISKLCVTMHQ 2374
R R R FP++VNC I WF +WP +AL SV+ + LQ E K ISK +H
Sbjct: 2961 KLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHT 3020
Query: 2375 NVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETY 2434
+V+ + +RY YTTP S + +R+ GL KL+ T
Sbjct: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
Query: 2435 DVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXX 2494
V ++ ++ E L +K ++ L++ + +E K
Sbjct: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
Query: 2495 XXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILM---G 2551
LA A PA+ ++ ELK+F PP V V V +LM G
Sbjct: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
Query: 2552 VKP---DWDSTKKLLADVN-FIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSK 2607
P W + K +A V+ F+ L +++K++I + LK I+ YL +FNP+ V S
Sbjct: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSY 3260
Query: 2608 VCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKM 2667
+ WV I + +VF VEPK +A A L + L A + ++ + LAK+
Sbjct: 3261 AAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKL 3320
Query: 2668 MDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDI 2727
+ ++LK Q + ++ A +S A +L LA E RW ++V+ QQ GDI
Sbjct: 3321 TARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDI 3380
Query: 2728 IVASGCIAYFGAFPSHYRRE-LELKWIAECSELEIP 2762
++ + I+Y G F YR+ L+ W S+L+ P
Sbjct: 3381 LLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP 3416
Score = 182 bits (442), Expect = 2e-44
Identities = 102/368 (27%), Positives = 181/368 (49%), Gaps = 2/368 (0%)
Query: 569 IREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQN 628
I E +F++ +QL + +V + LW +W P+ ++V+ ++
Sbjct: 1275 ISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMEL 1334
Query: 629 TTISYGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILH 688
+ + LDK + + + + L ++ L+NPA++ RHW ++ +
Sbjct: 1335 ECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATG 1394
Query: 689 TRFTPDVVMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILH 748
FT D L +LQ + DE+ + +A+ E G+E LK+++ WA +EF H
Sbjct: 1395 VSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPH 1454
Query: 749 KDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+V +L +++ L+++ + + ++ S+ V W K L + W+
Sbjct: 1455 PRT-NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWF 1513
Query: 809 ACQQTWMYLEVIFS-APDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLY 867
Q+TW +LE IF+ + DI+ QLP +++ F +D +K++ K+P + +P LY
Sbjct: 1514 EVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLY 1573
Query: 868 EEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCF 927
E+ L K L YL+TKR+AFPRF+FLS+ +LL+IL+ P VQ HL K F
Sbjct: 1574 EKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLF 1633
Query: 928 DAIAKLEF 935
D +AK+ F
Sbjct: 1634 DNMAKMRF 1641
>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy chain
9 protein.
Length = 4486
Score = 1053 bits (2607), Expect = 0.0
Identities = 627/1836 (34%), Positives = 957/1836 (52%), Gaps = 49/1836 (2%)
Query: 944 MEIAEDGTL---VEKEMSFQTRDMLQAKLAKTASPEDLTTDIVAMLSPEGERVNLGKGLK 1000
++I +GT V++ +S +M + + AS E T + M S E E V +
Sbjct: 1613 LDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSL-GMYSKEEEYVAFSEPCD 1671
Query: 1001 ARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGV 1060
G VE WL V M A+V+ M + Y R W+ HP QV LT +QI W V
Sbjct: 1672 CSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEV 1731
Query: 1061 HEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTLLFRKVLCALITIDVHARDTI 1120
F + ++ + Y KK ++ L L + L+ R+ + + TIDVHARD +
Sbjct: 1732 GMAF-ARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVV 1790
Query: 1121 SHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTD 1180
+ M+ + V A F WL +R+ W++++ +C A + A ++Y +EYLG LVITPLTD
Sbjct: 1791 AKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTD 1850
Query: 1181 RCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFS 1240
RCY+ L +L L + DL ++L I VFNCSE +DYK G +
Sbjct: 1851 RCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYK 1910
Query: 1241 GLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMFEGREIKLVRTCAAFI 1300
GLA +GAW CFDEFNRI +EVLSV+A Q+ +I++A K+ F F G EI L + FI
Sbjct: 1911 GLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFI 1970
Query: 1301 TMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLS 1360
TMNPGYAGRTELP+NLK+LFRP +M+VPD+ LI E++L +EGF ++ LA+K + +Y+L
Sbjct: 1971 TMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLC 2030
Query: 1361 SEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILF 1420
E LSKQDHYD+G+RA+KSVLV+AG+LKR +PD+ E+ L+ +L D N+PK + D +F
Sbjct: 2031 KELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIF 2090
Query: 1421 AGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVIQLHETMIVRWGVMLV 1480
G++ DLFP + +P R E +++ +++ KLQ E + KV+QL E + VR V +V
Sbjct: 2091 MGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVV 2150
Query: 1481 GPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEW 1540
G G GK+ VL L TY + + +PV +NPK++T EL+G +N T EW
Sbjct: 2151 GGAGTGKSQVLRSLHKTYQIM--------KRRPVWT-DLNPKAVTNDELFGIINPATGEW 2201
Query: 1541 HDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIENMNTVLDDNKMLCLSNSERIKLTPY 1600
DG+ +R + +W++ DG +D +WIE++NTV+DDNK+L L+++ERI L P
Sbjct: 2202 KDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPT 2261
Query: 1601 VHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRSWLQEGVEKNLFNQENSDFIYE 1660
+ ++FE++ L A+PATVSR G++YI+P ++G+ P V SW +EK E ++
Sbjct: 2262 MKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSW----IEKREIQTERANLTIL 2317
Query: 1661 LFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLGALLAEPGDRFADKAALKIYIAHCF 1720
K LD + I + S V C LL LL D AD +IY H F
Sbjct: 2318 FDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTE-DIPAD-CPKEIY-EHYF 2374
Query: 1721 IFCYVWCIGGNILEMNRQSFE-EVIKRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWA 1779
+F +W GG +++ + E K E++ ++ QG FD Y+D +K + W+
Sbjct: 2375 VFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQG-TIFDYYIDPETKKFEPWS 2433
Query: 1780 EIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILN 1839
+++P+F +D P LV T +T+R Y E+L+ +PVM G G GK+ + L
Sbjct: 2434 KLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLA 2493
Query: 1840 RMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKL 1899
+ Y V + F+ T+S Q V+E L+K+ + G P KK+I FIDD+NMP++
Sbjct: 2494 SLDPEAYLVKNV-PFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEV 2552
Query: 1900 DVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFA 1959
D YG ++RQ LD+G YDR KL K+I +V SC P G + R RHF+
Sbjct: 2553 DAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQY-VSCMNPTAGSFTINPRLQRHFS 2611
Query: 1960 MLYIAAPNADAMKTIFKAILKGHME--DFVPEVSVLGESIVNAAVEVYLKICAELLPTPA 2017
+ ++ P ADA+ +I+ IL H++ +F + +++ A+ + KI LPT
Sbjct: 2612 VFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGI 2671
Query: 2018 KSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHL 2077
K HY+FNLRD + QG+L + ++S ++RL+ HE RV+ D+++ +D F +
Sbjct: 2672 KFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKI 2731
Query: 2078 MASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNS-SVPKENRTYQEIPDISKLMIVLK 2136
V +K F ++P+ + L+ F N PK Y + L L
Sbjct: 2732 QTEVLKKTFDD-----IEDPVEQTQSPNLYCHFANGIGEPK----YMPVQSWELLTQTLV 2782
Query: 2137 EYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHV 2196
E L+ +N M LVLF+D G+ L+VG GGSG++S+ LA +
Sbjct: 2783 EALENHNE-VNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFI 2841
Query: 2197 NECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLN 2256
+ + L++ Y +F DL + ++AGV +TVFL TD Q+ E FL IN+LL
Sbjct: 2842 SSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLA 2901
Query: 2257 SGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGE 2316
SGE+P+L+ D E + + R E G+ +R+ + FFI+R+R +L + +C SPVG
Sbjct: 2902 SGEIPDLYSDDEVENIISNVRNEVKSQGL-VDNRENCWKFFIDRIRRQLKVTLCFSPVGN 2960
Query: 2317 AFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQEIITK--ISKLCVTMHQ 2374
R R R FP++VNC I WF +WP +AL SV+ + LQ E K ISK +H
Sbjct: 2961 KLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHT 3020
Query: 2375 NVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETY 2434
+V+ + +RY YTTP S + +R+ GL KL+ T
Sbjct: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
Query: 2435 DVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXX 2494
V ++ ++ E L +K ++ L++ + +E K
Sbjct: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
Query: 2495 XXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILM---G 2551
LA A PA+ ++ ELK+F PP V V V +LM G
Sbjct: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
Query: 2552 VKP---DWDSTKKLLADVN-FIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSK 2607
P W + K +A V+ F+ L +++K++I + LK I+ YL +FNP+ V S
Sbjct: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSY 3260
Query: 2608 VCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKM 2667
+ WV I + +VF VEPK +A A L + L A + ++ + LAK+
Sbjct: 3261 AAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKL 3320
Query: 2668 MDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDI 2727
+ ++LK Q + ++ A +S A +L LA E RW ++V+ QQ GDI
Sbjct: 3321 TARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDI 3380
Query: 2728 IVASGCIAYFGAFPSHYRRE-LELKWIAECSELEIP 2762
++ + I+Y G F YR+ L+ W S+L+ P
Sbjct: 3381 LLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP 3416
Score = 182 bits (442), Expect = 2e-44
Identities = 102/368 (27%), Positives = 181/368 (49%), Gaps = 2/368 (0%)
Query: 569 IREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQN 628
I E +F++ +QL + +V + LW +W P+ ++V+ ++
Sbjct: 1275 ISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMEL 1334
Query: 629 TTISYGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILH 688
+ + LDK + + + + L ++ L+NPA++ RHW ++ +
Sbjct: 1335 ECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATG 1394
Query: 689 TRFTPDVVMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILH 748
FT D L +LQ + DE+ + +A+ E G+E LK+++ WA +EF H
Sbjct: 1395 VSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPH 1454
Query: 749 KDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+V +L +++ L+++ + + ++ S+ V W K L + W+
Sbjct: 1455 PRT-NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWF 1513
Query: 809 ACQQTWMYLEVIFS-APDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLY 867
Q+TW +LE IF+ + DI+ QLP +++ F +D +K++ K+P + +P LY
Sbjct: 1514 EVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLY 1573
Query: 868 EEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCF 927
E+ L K L YL+TKR+AFPRF+FLS+ +LL+IL+ P VQ HL K F
Sbjct: 1574 EKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLF 1633
Query: 928 DAIAKLEF 935
D +AK+ F
Sbjct: 1634 DNMAKMRF 1641
>AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein.
Length = 2992
Score = 1053 bits (2607), Expect = 0.0
Identities = 627/1836 (34%), Positives = 957/1836 (52%), Gaps = 49/1836 (2%)
Query: 944 MEIAEDGTL---VEKEMSFQTRDMLQAKLAKTASPEDLTTDIVAMLSPEGERVNLGKGLK 1000
++I +GT V++ +S +M + + AS E T + M S E E V +
Sbjct: 195 LDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSL-GMYSKEEEYVAFSEPCD 253
Query: 1001 ARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGV 1060
G VE WL V M A+V+ M + Y R W+ HP QV LT +QI W V
Sbjct: 254 CSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEV 313
Query: 1061 HEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTLLFRKVLCALITIDVHARDTI 1120
F + ++ + Y KK ++ L L + L+ R+ + + TIDVHARD +
Sbjct: 314 GMAF-ARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVV 372
Query: 1121 SHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTD 1180
+ M+ + V A F WL +R+ W++++ +C A + A ++Y +EYLG LVITPLTD
Sbjct: 373 AKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTD 432
Query: 1181 RCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFS 1240
RCY+ L +L L + DL ++L I VFNCSE +DYK G +
Sbjct: 433 RCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYK 492
Query: 1241 GLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMFEGREIKLVRTCAAFI 1300
GLA +GAW CFDEFNRI +EVLSV+A Q+ +I++A K+ F F G EI L + FI
Sbjct: 493 GLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFI 552
Query: 1301 TMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLS 1360
TMNPGYAGRTELP+NLK+LFRP +M+VPD+ LI E++L +EGF ++ LA+K + +Y+L
Sbjct: 553 TMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLC 612
Query: 1361 SEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILF 1420
E LSKQDHYD+G+RA+KSVLV+AG+LKR +PD+ E+ L+ +L D N+PK + D +F
Sbjct: 613 KELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIF 672
Query: 1421 AGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVIQLHETMIVRWGVMLV 1480
G++ DLFP + +P R E +++ +++ KLQ E + KV+QL E + VR V +V
Sbjct: 673 MGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVV 732
Query: 1481 GPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEW 1540
G G GK+ VL L TY + + +PV +NPK++T EL+G +N T EW
Sbjct: 733 GGAGTGKSQVLRSLHKTYQIM--------KRRPVWT-DLNPKAVTNDELFGIINPATGEW 783
Query: 1541 HDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIENMNTVLDDNKMLCLSNSERIKLTPY 1600
DG+ +R + +W++ DG +D +WIE++NTV+DDNK+L L+++ERI L P
Sbjct: 784 KDGLFSSIMRELANTTHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPT 843
Query: 1601 VHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRSWLQEGVEKNLFNQENSDFIYE 1660
+ ++FE++ L A+PATVSR G++YI+P ++G+ P V SW +EK E ++
Sbjct: 844 MKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSW----IEKREIQTERANLTIL 899
Query: 1661 LFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLGALLAEPGDRFADKAALKIYIAHCF 1720
K LD + I + S V C LL LL D AD +IY H F
Sbjct: 900 FDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTE-DIPAD-CPKEIY-EHYF 956
Query: 1721 IFCYVWCIGGNILEMNRQSFE-EVIKRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWA 1779
+F +W GG +++ + E K E++ ++ QG FD Y+D +K + W+
Sbjct: 957 VFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQG-TIFDYYIDPETKKFEPWS 1015
Query: 1780 EIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILN 1839
+++P+F +D P LV T +T+R Y E+L+ +PVM G G GK+ + L
Sbjct: 1016 KLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLA 1075
Query: 1840 RMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKL 1899
+ Y V + F+ T+S Q V+E L+K+ + G P KK+I FIDD+NMP++
Sbjct: 1076 SLDPEAYLVKNV-PFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEV 1134
Query: 1900 DVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFA 1959
D YG ++RQ LD+G YDR KL K+I +V SC P G + R RHF+
Sbjct: 1135 DAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQY-VSCMNPTAGSFTINPRLQRHFS 1193
Query: 1960 MLYIAAPNADAMKTIFKAILKGHME--DFVPEVSVLGESIVNAAVEVYLKICAELLPTPA 2017
+ ++ P ADA+ +I+ IL H++ +F + +++ A+ + KI LPT
Sbjct: 1194 VFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGI 1253
Query: 2018 KSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHL 2077
K HY+FNLRD + QG+L + ++S ++RL+ HE RV+ D+++ +D F +
Sbjct: 1254 KFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKI 1313
Query: 2078 MASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNS-SVPKENRTYQEIPDISKLMIVLK 2136
V +K F ++P+ + L+ F N PK Y + L L
Sbjct: 1314 QTEVLKKTFDD-----IEDPVEQTQSPNLYCHFANGIGEPK----YMPVQSWELLTQTLV 1364
Query: 2137 EYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHV 2196
E L+ +N M LVLF+D G+ L+VG GGSG++S+ LA +
Sbjct: 1365 EALENHNE-VNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFI 1423
Query: 2197 NECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLN 2256
+ + L++ Y +F DL + ++AGV +TVFL TD Q+ E FL IN+LL
Sbjct: 1424 SSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLA 1483
Query: 2257 SGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGE 2316
SGE+P+L+ D E + + R E G+ +R+ + FFI+R+R +L + +C SPVG
Sbjct: 1484 SGEIPDLYSDDEVENIISNVRNEVKSQGL-VDNRENCWKFFIDRIRRQLKVTLCFSPVGN 1542
Query: 2317 AFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQEIITK--ISKLCVTMHQ 2374
R R R FP++VNC I WF +WP +AL SV+ + LQ E K ISK +H
Sbjct: 1543 KLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHT 1602
Query: 2375 NVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETY 2434
+V+ + +RY YTTP S + +R+ GL KL+ T
Sbjct: 1603 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 1662
Query: 2435 DVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXX 2494
V ++ ++ E L +K ++ L++ + +E K
Sbjct: 1663 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 1722
Query: 2495 XXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILM---G 2551
LA A PA+ ++ ELK+F PP V V V +LM G
Sbjct: 1723 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 1782
Query: 2552 VKP---DWDSTKKLLADVN-FIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSK 2607
P W + K +A V+ F+ L +++K++I + LK I+ YL +FNP+ V S
Sbjct: 1783 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSY 1842
Query: 2608 VCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKM 2667
+ WV I + +VF VEPK +A A L + L A + ++ + LAK+
Sbjct: 1843 AAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKL 1902
Query: 2668 MDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDI 2727
+ ++LK Q + ++ A +S A +L LA E RW ++V+ QQ GDI
Sbjct: 1903 TARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDI 1962
Query: 2728 IVASGCIAYFGAFPSHYRRE-LELKWIAECSELEIP 2762
++ + I+Y G F YR+ L+ W S+L+ P
Sbjct: 1963 LLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP 1998
Score = 140 bits (338), Expect = 9e-32
Identities = 73/224 (32%), Positives = 122/224 (54%), Gaps = 2/224 (0%)
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNI 772
E+ + +A+ E G+E LK+++ WA +EF H +V +L +++ L+++ +
Sbjct: 1 EVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT-NVPLLCSDEDLIEVLEDNQV 59
Query: 773 HISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFS-APDIQRQLP 831
+ ++ S+ V W K L + W+ Q+TW +LE IF+ + DI+ QLP
Sbjct: 60 QLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLP 119
Query: 832 NETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETK 891
+++ F +D +K++ K+P + +P LYE+ L K L YL+TK
Sbjct: 120 QDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTK 179
Query: 892 RVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEF 935
R+AFPRF+FLS+ +LL+IL+ P VQ HL K FD +AK+ F
Sbjct: 180 RLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRF 223
>AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy chain
dynein type 11 protein.
Length = 4523
Score = 1045 bits (2588), Expect = 0.0
Identities = 608/1795 (33%), Positives = 932/1795 (51%), Gaps = 55/1795 (3%)
Query: 983 VAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNERVDWVEM 1042
V M S E E V + G+VE WL ++E+ M +V+ + A+ Y R W+
Sbjct: 1682 VGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFD 1741
Query: 1043 HPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTLLF 1102
P QV LT SQI W V F+ + +T L + KK IS LN L L +L
Sbjct: 1742 FPAQVALTSSQIWWTTDVGIAFS-RLEEGYETALKDFHKKQISQLNTLITLLLGELPPGD 1800
Query: 1103 RKVLCALITIDVHARDTISHMVEKH--VQKANDFEWLKMIRYYWEEDIDNCVARMSSAMY 1160
R+ + + TIDVHARD ++ ++ + V F WL +R+ WE+ +C + A +
Sbjct: 1801 RQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQF 1860
Query: 1161 IYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQ 1220
Y +EYLG LVITPLTDRCY+ L +L L + DL ++L +
Sbjct: 1861 QYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMM 1920
Query: 1221 CVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQ 1280
VFNCSE +DYK +G + GL +GAW CFDEFNRI +EVLSV+A Q+ I +A ++
Sbjct: 1921 VYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRK 1980
Query: 1281 TRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYS 1340
RF+F G I L + FITMNPGYAGRTELP+NLKALFRP +M+ PD LI E++L +
Sbjct: 1981 KRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVA 2040
Query: 1341 EGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTL 1400
EGF ++ LA+K + +Y L E LSKQDHYD+G+RA+KSVLV+AG+LKR + ++ E+ L
Sbjct: 2041 EGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVL 2100
Query: 1401 LCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQ 1460
+ AL D N+PK + D +F G++ DLFP + +P R E +++ LE +LQ E
Sbjct: 2101 MRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESF 2160
Query: 1461 IRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMN 1520
I KV+QL E + VR V +VG G GK+ +L L TY + + V +N
Sbjct: 2161 ILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWND---------LN 2211
Query: 1521 PKSLTIGELYGEVNLQTLEWHD---------GILPLCLRTAVQCLNPDHQWLICDGPVDA 1571
PK++T EL+G ++ T EW D G+ LR + +W++ DG +D
Sbjct: 2212 PKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDP 2271
Query: 1572 VWIENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEM 1631
+WIE++NTV+DDNK+L L+++ERI LTP++ ++FE+ L A+PATVSR G++Y++P ++
Sbjct: 2272 MWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDL 2331
Query: 1632 GYLPFVRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQ 1691
G+ P+V SW +++ E ++ K LD + + + S V
Sbjct: 2332 GWNPYVASW----IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTL 2387
Query: 1692 CFLLGALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEY 1751
C LL LL + + ++Y + F+F +W GG +L+ ++ R +++
Sbjct: 2388 CVLLECLLTP--ENVPSDSPKEVYEVY-FVFACIWAFGGTLLQDQISDYQADFSRWWQKE 2444
Query: 1752 EEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPEFIYDCNKPFFETLVPTIDTVRYGYLFE 1811
+A +P FD Y+D + +KL WA+ I +F D + P LV T +T R Y E
Sbjct: 2445 MKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFME 2504
Query: 1812 KLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRL 1871
LL GKP+M GN GVGKT + L SL+ Y+ + F+ T+S Q+++E L
Sbjct: 2505 LLLEKGKPLMLVGNAGVGKTVFVGDTL--ASLSEDYIVSRVPFNYYTTSTALQKILEKPL 2562
Query: 1872 DKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDI 1931
+K+ G KK+I FIDD+NMP++D+YG L+RQ +D+G YDR K+ K+I
Sbjct: 2563 EKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEI 2622
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMED--FVPE 1989
+ +C P G ++ R RHF + P+ DA+ TI+ I H + F P
Sbjct: 2623 HNCQY-VACMNPMVGSFTISPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPS 2681
Query: 1990 VSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGM 2049
+ G +++ A + + + LPT K HY+FNLRDLS QG+L A ++ P +
Sbjct: 2682 ILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDL 2741
Query: 2050 LRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEHPPLLLFGD 2109
+ L+ HE RV+ D+LI+ +D F M K F+ + +++ P L++
Sbjct: 2742 IHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE----GIDSHMLLQQP--LIYCH 2795
Query: 2110 FLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXX 2169
F + ++ Y + D L +L E LD YN A MHLVLF+D
Sbjct: 2796 FADRG---KDPHYMPVKDWEVLKTILTETLDNYNE-LNAAMHLVLFEDAMQHVCRISRIL 2851
Query: 2170 XXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVN 2229
G L+VG GGSG++S++ LA ++ + + L Y E DL +Y+R G
Sbjct: 2852 RTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAK 2911
Query: 2230 CEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSD 2289
TVFL TD Q+ E FL IN+LL SGE+P+LF + +++ +G E G+ S
Sbjct: 2912 NMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDS- 2970
Query: 2290 RDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVA 2349
R+ + FF+ RVR +L + +C SPVG R R R FP++VNC IDWF WP EAL+SV+
Sbjct: 2971 RENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVS 3030
Query: 2350 HQCLQPLGNQEIITK--ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXX 2407
+ ++ E + K IS +H V+ M+ R Y RR+ YTTP S
Sbjct: 3031 RRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKN 3090
Query: 2408 XXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKI 2467
+ ++R+ G+QKL T VG ++ ++ E L + ++ AL+ ++ +
Sbjct: 3091 LLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGL 3150
Query: 2468 EQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDIN 2527
+ + K L A PA+ +++
Sbjct: 3151 QTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLS 3210
Query: 2528 ELKAFQKPPALVRFVMEPVCILM---GVKP---DWDSTKKLLADV-NFIGKLADYDKDHI 2580
ELKAF PP V V V +L+ G P W + K + V +F+ L +YDK+HI
Sbjct: 3211 ELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHI 3270
Query: 2581 PDATLKKI-KVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEA 2639
P+ LK + + YL +FNP+ + S + WV I + +V+ VEPK +A
Sbjct: 3271 PENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQA 3330
Query: 2640 AAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLT 2699
L + L A +K++ ++ L+++ + E+++ Q +V+ + A +L
Sbjct: 3331 NLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLV 3390
Query: 2700 QALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRREL-ELKWI 2753
+ L +K RW +S+K+ Q GD+++ + ++Y G F YR+EL KW+
Sbjct: 3391 KELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWV 3445
Score = 171 bits (417), Expect = 2e-41
Identities = 106/396 (26%), Positives = 192/396 (48%), Gaps = 7/396 (1%)
Query: 546 EKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKE 605
E LD E+L A Q++E ++F++ +Q+ + ++KL + LW
Sbjct: 1276 ENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIY 1335
Query: 606 WNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFN-----QLDKGLPSNTIVPKCKELIDVI 660
+W + + V+++ + K + L+K + + + +
Sbjct: 1336 VRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDM 1395
Query: 661 KEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDELMEVAGQ 720
L I+ L++PAL+ RHW ++ + + +F + L L+ + D++ + +
Sbjct: 1396 TASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDK 1455
Query: 721 ASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSS 780
A E G E ++ ++ + WA ++F +H + +L +++ +L+ + + + T+L S
Sbjct: 1456 AVKELGTEKVITEISQTWATMKFSYEVHYRT-GIPLLKSDEQLFETLEHNQVQLQTLLQS 1514
Query: 781 RNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIF-SAPDIQRQLPNETRLFSI 839
+ +V W L + + W Q+TW +LE IF + DI+ QL + R F
Sbjct: 1515 KYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDG 1574
Query: 840 VDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFF 899
VD +K++M K AKV + A +P LYE+ L K L YLETKR+AFPRF+
Sbjct: 1575 VDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFY 1634
Query: 900 FLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEF 935
F+S+ +LL+IL++ P V HL K FD+IA L+F
Sbjct: 1635 FVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQF 1670
>AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein.
Length = 2182
Score = 1018 bits (2520), Expect = 0.0
Identities = 494/1062 (46%), Positives = 680/1062 (64%), Gaps = 8/1062 (0%)
Query: 1708 DKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEYYPQGFNFFDMY 1767
++ L + F+FCY+W +GGN+ E SF+ I+ QF++ +A P + + ++
Sbjct: 5 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARL-PNSGDLWSIH 63
Query: 1768 MDTRQRKLKVWAEIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTG 1827
MD ++L W IIP F Y+ + PFFE LVPT DTVRYGYL EKLL V+FTG TG
Sbjct: 64 MDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITG 123
Query: 1828 VGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKI 1887
VGK+ IA +LN++ + YVPV LNFSAQTSS RTQE+IE +L+++ + +GAP K+I
Sbjct: 124 VGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRI 183
Query: 1888 IIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGR 1947
+IF+DD+NMP+LD YG+QP IELLRQ+ DFGG YDR+KL+WK+I DV + +CAPPGGGR
Sbjct: 184 VIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGR 243
Query: 1948 NPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFVPEVSVLGESIVNAAVEVYLK 2007
NP+T RF+RHF+ML + P+ ++K IF+AIL G + DF P V SIV A+VE+Y K
Sbjct: 244 NPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNK 303
Query: 2008 ICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLIN 2067
+ +LLPTPAKSHYVFNLRDLSK +QG+LQ +R + RLF HEC RVFHDRLIN
Sbjct: 304 MSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLIN 363
Query: 2068 IQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNSSVPKENRTYQEIPD 2127
+DK YF+ ++ + K+F +++ E + P ++FGDF+ K +R Y ++PD
Sbjct: 364 NEDKHYFHVILTEMANKHFG---IAIDLEYFLNKP--IIFGDFIKFGADKADRIYDDMPD 418
Query: 2128 ISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRR 2187
I K VL++YLD+YN T E+ LV FQD G+ L+VG GG+G++
Sbjct: 419 IEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQ 478
Query: 2188 SVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEF 2247
S+ LA H+ KCL +EL R Y+ FH+DLR +Y AGV ++ VFLFTDTQI EEF
Sbjct: 479 SLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEF 538
Query: 2248 LEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHL 2307
LEDINN+LNSGEVPNLFE D EQV R A + G++ +RD V+ +FI++VR KLH+
Sbjct: 539 LEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHI 598
Query: 2308 CICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPL--GNQEIITKI 2365
+CMSPVGEAFR RCRMFPSLVNCCTIDWF +WP EALLSV+ + GN+E+ K+
Sbjct: 599 VLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKL 658
Query: 2366 SKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISC 2425
+CV +H +V M +R Y E+RR +YTTP+S II RDR+
Sbjct: 659 PLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKN 718
Query: 2426 GLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXX 2485
GL KL ET +V M+ + +EP+L K+ + AL+E+L ++Q++AD+V+ V
Sbjct: 719 GLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEAT 778
Query: 2486 XXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEP 2545
L A+PA++ DI+E++ F KPP LV VME
Sbjct: 779 AKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEA 838
Query: 2546 VCILMGVKPDWDSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKV 2605
+ IL+ KPDW S K+LL D NF+ +L +YDK++I L K++ Y+ + DF P+ V KV
Sbjct: 839 ISILLNAKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKV 898
Query: 2606 SKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLA 2665
SK C+SM +WV+A+D+Y++V +VVEPK K + A A L MA LR KQ + +E Q+
Sbjct: 899 SKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQ 958
Query: 2666 KMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTG 2725
+ DE +E+ L + L ARL RAGKLT AL DE+ RWEES++ +++ TG
Sbjct: 959 ALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITG 1018
Query: 2726 DIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIPSSNTF 2767
++ +A+ C+AY+GAF + YR+ L WI +C LEIP +F
Sbjct: 1019 NVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSF 1060
>AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1687
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1688 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2105 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2154
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2155 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2214
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2215 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2274
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2275 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2329
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2330 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2385
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2386 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2444
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2445 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2503
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2504 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2563
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2564 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2623
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2624 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2683
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2684 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2743
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2744 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 2803
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 2804 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 2863
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 2864 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 2923
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 2924 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 2983
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 2984 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3043
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3044 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3103
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3104 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3223
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3224 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3283
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3284 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3343
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3344 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3403
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3404 NYLLKDQWEMELRARKIP 3421
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1255 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1314
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1315 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1374
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1375 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1434
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1435 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1494
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1495 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1554
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1555 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1614
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1615 INEVTFHAK 1623
>AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1687
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1688 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2105 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2154
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2155 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2214
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2215 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2274
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2275 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2329
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2330 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2385
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2386 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2444
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2445 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2503
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2504 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2563
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2564 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2623
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2624 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2683
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2684 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2743
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2744 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 2803
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 2804 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 2863
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 2864 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 2923
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 2924 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 2983
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 2984 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3043
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3044 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3103
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3104 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3223
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3224 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3283
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3284 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3343
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3344 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3403
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3404 NYLLKDQWEMELRARKIP 3421
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1255 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1314
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1315 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1374
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1375 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1434
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1435 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1494
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1495 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1554
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1555 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1614
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1615 INEVTFHAK 1623
>AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1687
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1688 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2105 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2154
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2155 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2214
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2215 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2274
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2275 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2329
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2330 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2385
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2386 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2444
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2445 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2503
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2504 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2563
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2564 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2623
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2624 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2683
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2684 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2743
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2744 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 2803
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 2804 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 2863
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 2864 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 2923
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 2924 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 2983
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 2984 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3043
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3044 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3103
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3104 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3223
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3224 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3283
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3284 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3343
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3344 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3403
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3404 NYLLKDQWEMELRARKIP 3421
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1255 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1314
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1315 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1374
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1375 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1434
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1435 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1494
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1495 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1554
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1555 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1614
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1615 INEVTFHAK 1623
>AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1833 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1892
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1893 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1949
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1950 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 2009
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 2010 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 2069
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 2070 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 2129
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 2130 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 2189
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 2190 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2249
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2250 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2309
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2310 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2359
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2360 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2419
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2420 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2479
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2480 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2534
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2535 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2590
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2591 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2649
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2650 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2708
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2709 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2768
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2769 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2828
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2829 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2888
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2889 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2948
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2949 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 3008
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 3009 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 3068
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 3069 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 3128
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 3129 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 3188
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 3189 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3248
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3249 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3308
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3309 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3368
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3369 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3428
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3429 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3488
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3489 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3548
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3549 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3608
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3609 NYLLKDQWEMELRARKIP 3626
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1460 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1519
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1520 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1579
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1580 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1639
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1640 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1699
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1700 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1759
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1760 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1819
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1820 INEVTFHAK 1828
>AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1687
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1688 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2105 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2154
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2155 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2214
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2215 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2274
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2275 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2329
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2330 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2385
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2386 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2444
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2445 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2503
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2504 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2563
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2564 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2623
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2624 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2683
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2684 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2743
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2744 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 2803
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 2804 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 2863
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 2864 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 2923
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 2924 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 2983
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 2984 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3043
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3044 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3103
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3104 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3223
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3224 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3283
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3284 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3343
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3344 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3403
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3404 NYLLKDQWEMELRARKIP 3421
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1255 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1314
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1315 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1374
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1375 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1434
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1435 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1494
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1495 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1554
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1555 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1614
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1615 INEVTFHAK 1623
>AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy chain
8 protein.
Length = 4490
Score = 921 bits (2279), Expect = 0.0
Identities = 572/1818 (31%), Positives = 921/1818 (50%), Gaps = 61/1818 (3%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN--ERVDW 1039
I+A++S EGE++ L + A+G VE WL + + +S+ ++ A + + + + +
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPF 1687
Query: 1040 VEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSY-EKKCISDLNDLAALTRKDL 1098
+ P QV L Q++W E + D ++ +K + LN L + T DL
Sbjct: 1688 LSHFPAQVGLLGIQMLWTHDSEEALR---NAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1099 TLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSA 1158
+ R LITI VH RD +V+ H++ DFEWLK R+Y++ED+D V ++
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1159 MYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLA 1218
+IY +E+LG LVITPLTDRCY+ L AL +++ D+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1219 IQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVA 1278
VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1279 KQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVI 1337
++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1338 LYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEE 1397
L S GF + LA+K +YKL EQL+KQ HYDFG+R + SVL G+ KRA P+ E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1398 MTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMED-VIKIIMLERKLQI 1456
++ L D NL K + D LF +++DLFPG+ L + Y +++ V + +E +
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1457 EICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRK 1516
+ K++QL+ET +VR G+M +GP+G GKT V+ +L T E G +P R+
Sbjct: 2105 PPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECG------RPHRE 2154
Query: 1517 YIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIEN 1576
MNPK++T +++G ++ T +W DGI R ++ ++ +LI DGPVDA+WIEN
Sbjct: 2155 MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIEN 2214
Query: 1577 MNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPF 1636
+N+VLDDNK L L+N +RI + P ++FEV ++ ASPATVSR GMVYI + + + P
Sbjct: 2215 LNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPI 2274
Query: 1637 VRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVSAQCFLLG 1696
+++WL K QE + F+ K+ + ++ N ++ ++ + + LL
Sbjct: 2275 LQAWL-----KKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLE 2329
Query: 1697 ALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEY 1756
L+ P + ++ ++ F+F +W +G +LE+ + E RQ E +
Sbjct: 2330 GLI--PSKEEGGVSCVE-HLHKLFVFGLMWSLGA-LLELESREKLEAFLRQHESKLDLPE 2385
Query: 1757 YPQGFN--FFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVRYGYLFEK 1812
P+G N ++ Y+ T + W + + + Y D + LVP +D +R +L +
Sbjct: 2386 IPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDT 2444
Query: 1813 LLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLD 1872
+ K V+ TG G KT + L + + LNFS+ T Q IE +D
Sbjct: 2445 IAKQHKAVLLTGEQGTAKTVMVKAYLKKYD-PEVQLSKSLNFSSATEPMMFQRTIESYVD 2503
Query: 1873 KRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDI 1931
KR G P G+K+ +FIDD+NMP ++ +G Q T E++RQ ++ G+Y DK + I
Sbjct: 2504 KRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTI 2563
Query: 1932 LDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHME---DFVP 1988
+DV L + PGGGRN + R R F + P+ ++ IF I G+ + F P
Sbjct: 2564 VDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKP 2623
Query: 1989 EVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQG 2048
++ + ++V+ ++ ++LPTP+K HY+FNLRDLS+ QG+L +A S
Sbjct: 2624 QICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPT 2683
Query: 2049 MLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILS--VPDEPIIEHPPLL- 2105
+L LF HEC RV DR I +D+ +F + E+N + S +P+ ++ +
Sbjct: 2684 LLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMP 2743
Query: 2106 -LFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVLFQDXXXXXX 2163
GD SV + + Y+ +P L L+ Y ++N R + LV F+D
Sbjct: 2744 EPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLI 2803
Query: 2164 XXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMY 2223
G+ L+VG GGSG++S++ LA + + + L R+Y+ DDL+ +Y
Sbjct: 2804 KISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALY 2863
Query: 2224 MRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKS 2283
AG + + F+FTD++I E FLE +NNLL+SGE+ NLF D +++ G + +
Sbjct: 2864 KVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE 2923
Query: 2284 -GVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPP 2342
+P D +Y +FI+R R LH+ +C SPVGE FR R FP L++ CT+DWF++WP
Sbjct: 2924 LPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPR 2983
Query: 2343 EALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXX 2399
EAL++VA L + EI ++ + H V + + RR + TP S
Sbjct: 2984 EALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYL 3043
Query: 2400 XXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESI 2459
I +R++ GL KL E + V + Q + E LA + ++
Sbjct: 3044 SFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKAD 3103
Query: 2460 ALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXX 2519
++ + + +A+ ++K V L A PA+E
Sbjct: 3104 EVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 2520 XXXXXDINELKAFQKPPALVRFVMEPVCILMG--------------VKPDWDSTKKLLAD 2565
DI ++ KPP L+ +M+ V +L KP W + KL++
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSA 3223
Query: 2566 VNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKV 2625
F+ L + KD I + T++ ++ Y D+ ++ KV ++ W A+ ++ +
Sbjct: 3224 TGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGI 3283
Query: 2626 FRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADV 2685
R V P + L A L Q ++ +A+L K+ + +E++ L D
Sbjct: 3284 NREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDA 3343
Query: 2686 DLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYR 2745
D ++ A L L+ EK RW + K Q++ GDI++ +G ++Y G F +R
Sbjct: 3344 DTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFR 3403
Query: 2746 RE-LELKWIAECSELEIP 2762
L+ +W E +IP
Sbjct: 3404 NYLLKDQWEMELRARKIP 3421
Score = 183 bits (446), Expect = 7e-45
Identities = 106/369 (28%), Positives = 178/369 (48%), Gaps = 3/369 (0%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P E L + ++ L Q L+ +Y+ + +D+++I +
Sbjct: 1255 EQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLE 1314
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFT 692
+ +L KGL K+ ID E P++ + N A+K RHW +I E+ T F
Sbjct: 1315 FQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFD 1374
Query: 693 PDV-VMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E +H D++ ++ A E +E+ L +V E W K
Sbjct: 1375 VESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGK 1434
Query: 752 RDVYVLGGLD-EIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI +++S + + ++LS+R P K ++ W L + +EEW
Sbjct: 1435 GELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVV 1494
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + F +DKSW IM++ + P + + +
Sbjct: 1495 QNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQL 1554
Query: 871 VRN-NEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDA 929
+ + +E L+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +QPHL D
Sbjct: 1555 LPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDN 1614
Query: 930 IAKLEFGVK 938
I ++ F K
Sbjct: 1615 INEVTFHTK 1623
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy chain
DNAH5 protein.
Length = 4624
Score = 883 bits (2184), Expect = 0.0
Identities = 572/1829 (31%), Positives = 892/1829 (48%), Gaps = 70/1829 (3%)
Query: 976 EDLTTDIVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVN- 1034
E + I+++ S EGE + L K + A GNVE WL + E +S+ ++ A
Sbjct: 1756 EKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETG 1815
Query: 1035 -ERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDL-NDLAA 1092
+ +++ P QV L Q++W + E + D ++ + +L N L
Sbjct: 1816 FQLTEFLSSFPAQVGLLGIQMIWTRDSEEALR---NAKFDKKIMQKTNQAFLELLNTLID 1872
Query: 1093 LTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCV 1152
+T +DL+ R LITI VH RD + H++ DFEWLK R+Y+ ED D +
Sbjct: 1873 VTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMM 1932
Query: 1153 ARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXD 1212
++ +IY +E+LG LVITPLTDRCY+ L AL + + D
Sbjct: 1933 IHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKD 1992
Query: 1213 LAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITI 1272
+ + L VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRID+ VLSV AQQ+ I
Sbjct: 1993 MGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISII 2052
Query: 1273 RNAKVAKQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYA 1331
K + F+F +G + + F+TMNPGYAGR ELP+NLK FR ++MMVPD
Sbjct: 2053 LTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQ 2112
Query: 1332 LIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRAN 1391
+I V L S GF + LA+K +YKL EQLSKQ HYDFG+R + SVL GA KRAN
Sbjct: 2113 IIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRAN 2172
Query: 1392 PDQHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLE 1451
P E ++ L D NL K + D LF ++ DLFP + L Y +E I + E
Sbjct: 2173 PMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEE 2232
Query: 1452 RKLQIEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQY 1511
L KVIQL ET VR G+M +GP+G GKT +H L T + G
Sbjct: 2233 AGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT---DCG------ 2283
Query: 1512 QPVRKYIMNPKSLTIGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDA 1571
+P R+ MNPK++T +++G +++ T +W DGI R ++ +H W+I DGPVDA
Sbjct: 2284 KPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDA 2343
Query: 1572 VWIENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEM 1631
+WIEN+N+VLDDNK L L+N +RI + P ++FE ++ ASPATVSR GMV++ + +
Sbjct: 2344 IWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSIL 2403
Query: 1632 GYLPFVRSWLQE--GVEKNLFNQENSDFIYELFKMTQVGLDHVNYNCGVGIKQVDISKVS 1689
+ P + +L++ E + Q ++ +L++ + ++ Y V V ++
Sbjct: 2404 DWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFC---IQNLEYKMEVLEAFVITQSIN 2460
Query: 1690 AQCFLLGAL-LAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIK-RQ 1747
L G + L E G + + ++ F+F +W G + R+ E ++ R
Sbjct: 2461 ---MLQGLIPLKEQGGEVS-----QAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRP 2512
Query: 1748 FEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPEFIY--DCNKPFFETLVPTIDTVR 1805
E G FD Y+ W E++Y D + LVP +D VR
Sbjct: 2513 TGTLELPPPAGPGDTAFDYYV-APDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVR 2571
Query: 1806 YGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQE 1865
+L + + GK V+ G G KT I +++ + + LNFS+ T+ Q
Sbjct: 2572 TDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIK-SLNFSSATTPLMFQR 2630
Query: 1866 VIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDK 1925
IE +DKR G P GKK+ +FIDDVNMP ++ +G Q T E++RQ ++ G Y+ +K
Sbjct: 2631 TIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEK 2690
Query: 1926 L-YWKDILDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGH-- 1982
+ I+D+ + PGGGRN + R R F++ P+ ++ IF I GH
Sbjct: 2691 PGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYC 2750
Query: 1983 -MEDFVPEVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAA 2041
F EV +V ++ ++LPTPAK HYVFNLRDLS+ QG+L +
Sbjct: 2751 TQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSE 2810
Query: 2042 YMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEH 2101
++ P +L+L+ HEC RV DR D ++F + S+ E+ F + D I +
Sbjct: 2811 VIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTY 2870
Query: 2102 PPLLL------FGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTAR-AEMHLVL 2154
L G+ + + + Y+ I S L L +L YN + R A M +V
Sbjct: 2871 FVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVF 2930
Query: 2155 FQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPE 2214
F D G+ L+VG GGSG++S+ LA + + L R+Y+T
Sbjct: 2931 FADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSN 2990
Query: 2215 FHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQT 2274
+DL+++Y AG + F+FTD +I E FLE +NN+L+SGEV NLF D +++ +
Sbjct: 2991 LMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINS 3050
Query: 2275 GCRTEAAKSGVN--PSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCC 2332
+ K P++ + ++ +F++RVR LH+ +C SPVGE FR R FP+L++ C
Sbjct: 3051 DLASVMKKEFPRCLPTN-ENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGC 3109
Query: 2333 TIDWFTKWPPEALLSVAHQCLQPLG---NQEIITKISKLCVTMHQNVDMMTDRLYMEMRR 2389
TIDWF++WP +AL++V+ L + EI ++ + + V + RR
Sbjct: 3110 TIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRR 3169
Query: 2390 YFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEP 2449
+ TP S + +R++ GL+KL E + V + +++ E
Sbjct: 3170 STHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEK 3229
Query: 2450 ILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMP 2509
L ++ +++ + ++ +AA++VK V L A P
Sbjct: 3230 ELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKP 3289
Query: 2510 AMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILMGVK--------------PD 2555
A+E DI ++ +PP L+ +M+ V +L K P
Sbjct: 3290 ALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS 3349
Query: 2556 WDSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLW 2615
W + KL+ NF+ L + KD I + ++ + Y D+N +T +V + W
Sbjct: 3350 WQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSW 3409
Query: 2616 VQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAV--LRAKQKEVEAIEAQLAKMMDELKT 2673
+A+ + + + V P LK + ++A+ L+ Q E++ +A+L + E +
Sbjct: 3410 TKAMASFFSINKEVLP--LKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQ 3467
Query: 2674 VEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGC 2733
E+ L D + ++ A L LA EK RW E + Q GD+++A+
Sbjct: 3468 AMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAF 3527
Query: 2734 IAYFGAFPSHYRRELELKWIAECSELEIP 2762
++Y G F +R L W E +IP
Sbjct: 3528 LSYSGPFNQEFRDLLLNDWRKEMKARKIP 3556
Score = 187 bits (456), Expect = 4e-46
Identities = 109/388 (28%), Positives = 196/388 (50%), Gaps = 8/388 (2%)
Query: 573 QKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTIS 632
+++F +P + QL E + L Q ++ + S+YD ++ +++++I N +
Sbjct: 1389 EELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLE 1448
Query: 633 YGKIFNQLDKGLPSNTIVPKCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEIL-HTRF 691
+ +L + L K++ID E P++ Y+ + A+ RHW +I + H+
Sbjct: 1449 FQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLD 1508
Query: 692 TPDVVMNLQMFEELQAFQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA 751
+ L+ E ++ +E+ ++ A E +E LK+V W F K
Sbjct: 1509 VGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTR 1568
Query: 752 RDVYVLG-GLDEIQASLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYAC 810
++ + G EI A++++S + + ++LS+R P K+++++W + L +E W
Sbjct: 1569 GELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTV 1628
Query: 811 QQTWMYLEVIFSAPDIQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEF 870
Q W+YLE +F DI +QLP E + FS +DKSW IM + +VP + + +
Sbjct: 1629 QNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQL 1688
Query: 871 VRNNEMLDQI---MKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCF 927
+ + +LDQ+ K L YLE KR+ FPRFFF+S+ LLEIL Q + H +Q HL F
Sbjct: 1689 LPH--LLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVF 1746
Query: 928 DAIAKLEFGVKFPESEMEI-AEDGTLVE 954
D I ++F K + + I +++G +E
Sbjct: 1747 DNIKSVKFHEKIYDRILSISSQEGETIE 1774
>AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1020
Score = 655 bits (1619), Expect = 0.0
Identities = 366/1044 (35%), Positives = 564/1044 (54%), Gaps = 41/1044 (3%)
Query: 1322 PISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVL 1381
P +M+ PD LI E++L +EGF ++ LA+K + +Y L E LSKQDHYD+G+RA+KSVL
Sbjct: 1 PCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 60
Query: 1382 VMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVM 1441
V+AG+LKR + ++ E+ L+ AL D N+PK + D +F G++ DLFP + +P R
Sbjct: 61 VVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHF 120
Query: 1442 EDVIKIIMLERKLQIEICQIRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRL 1501
E +++ LE +LQ E I KV+QL E + VR V +VG G GK+ +L L TY +
Sbjct: 121 EQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNM 180
Query: 1502 YENGVEGSQYQPVRKYIMNPKSLTIGELYGEVNLQTLEWHD---------GILPLCLRTA 1552
+ V +NPK++T EL+G ++ T EW D G+ LR
Sbjct: 181 KQKPVWND---------LNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQ 231
Query: 1553 VQCLNPDHQWLICDGPVDAVWIENMNTVLDDNKMLCLSNSERIKLTPYVHMVFEVADLAQ 1612
+ +W++ DG +D +WIE++NTV+DDNK+L L+++ERI LTP++ ++FE+ L
Sbjct: 232 ANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRS 291
Query: 1613 ASPATVSRCGMVYIDPNEMGYLPFVRSWLQEGVEKNLFNQENSDFIYELFKMTQVGLDHV 1672
A+PATVSR G++Y++P ++G+ P+V SW +++ E ++ K LD +
Sbjct: 292 ATPATVSRAGILYVNPQDLGWNPYVASW----IDRRRHQSEKANLTILFDKYVPACLDKL 347
Query: 1673 NYNCGVGIKQVDISKVSAQCFLLGALLAEPGDRFADKAALKIYIAHCFIFCYVWCIGGNI 1732
+ + S V C LL LL + + ++Y + F+F +W GG +
Sbjct: 348 RTSFKTITSIPESSLVQTLCVLLECLLTP--ENVPSDSPKEVYEVY-FVFACIWAFGGTL 404
Query: 1733 LEMNRQSFEEVIKRQFEEYEEAEYYPQGFNFFDMYMDTRQRKLKVWAEIIPEFIYDCNKP 1792
L+ ++ R +++ +A +P FD Y+D + +KL WA+ I +F D + P
Sbjct: 405 LQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVP 464
Query: 1793 FFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVGKTCIAVEILNRMSLTGYYVPVIL 1852
LV T +T R Y E LL GKP+M GN GVGKT + L SL+ Y+ +
Sbjct: 465 LQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTL--ASLSEDYIVSRV 522
Query: 1853 NFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELLR 1912
F+ T+S Q+++E L+K+ G KK+I FIDD+NMP++D+YG L+R
Sbjct: 523 PFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIR 582
Query: 1913 QFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGRNPLTARFVRHFAMLYIAAPNADAMK 1972
Q +D+G YDR K+ K+I + +C P G + R RHF + P+ DA+
Sbjct: 583 QHIDYGHWYDRQKVMLKEIHNCQY-VACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALN 641
Query: 1973 TIFKAILKGHMED--FVPEVSVLGESIVNAAVEVYLKICAELLPTPAKSHYVFNLRDLSK 2030
TI+ I H + F P + G +++ A + + + LPT K HY+FNLRDLS
Sbjct: 642 TIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSN 701
Query: 2031 SMQGVLQAQAAYMRSPQGMLRLFYHECLRVFHDRLINIQDKSYFYHLMASVCEKNFQTPI 2090
QG+L A ++ P ++ L+ HE RV+ D+LI+ +D F M K F+
Sbjct: 702 VFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE--- 758
Query: 2091 LSVPDEPIIEHPPLLLFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTARAEM 2150
+ +++ P L++ F + ++ Y + D L +L E LD YN A M
Sbjct: 759 -GIDSHMLLQQP--LIYCHFADRG---KDPHYMPVKDWEVLKTILTETLDNYNE-LNAAM 811
Query: 2151 HLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNY 2210
HLVLF+D G L+VG GGSG++S++ LA ++ + + L Y
Sbjct: 812 HLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGY 871
Query: 2211 DTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYE 2270
E DL +Y+R G TVFL TD Q+ E FL IN+LL SGE+P+LF + +
Sbjct: 872 GIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVD 931
Query: 2271 QVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVN 2330
++ +G E G+ S R+ + FF+ RVR +L + +C SPVG R R R FP++VN
Sbjct: 932 KIISGIHNEVHALGMVDS-RENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVN 990
Query: 2331 CCTIDWFTKWPPEALLSVAHQCLQ 2354
C IDWF WP EAL+SV+ + ++
Sbjct: 991 CTAIDWFHAWPQEALVSVSRRFIE 1014
>AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1
protein.
Length = 1964
Score = 535 bits (1320), Expect = e-151
Identities = 298/840 (35%), Positives = 453/840 (53%), Gaps = 44/840 (5%)
Query: 1896 MPKLDVYGAQPTIELLRQFLDFGGVYDRDKL-YWKDILDVVLSCSCAPPGGGRNPLTARF 1954
MP L+ YGAQP IELLRQ++D GG YDR + +K+++D+ C+ PPGGGRN +T R
Sbjct: 1 MPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRL 60
Query: 1955 VRHFAMLYIAAPNADAMKTIFKAILKGHMEDFV------------PEVSVLGESIVNAAV 2002
+RHF L A + + K IF IL ++ + P ++ E +V A +
Sbjct: 61 MRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATI 120
Query: 2003 EVYLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSPQGMLRLFYHECLRVFH 2062
VY I ++LLPTPAKSHY FNLRDLSK QG+L A A + +LRL+YHE RVF
Sbjct: 121 MVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFR 180
Query: 2063 DRLINIQDKSYFYHLMASVCEKNFQTPILSV-PDEPIIEHPPLLLFGDFLNSSVPKENRT 2121
DRL+N +D+S+F L+ C + ++ V P +PI L+GDF++ + ++
Sbjct: 181 DRLVNEEDRSWFDQLLKR-CMEQWEVTFNKVCPFQPI-------LYGDFMSPG--SDVKS 230
Query: 2122 YQEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGP 2181
Y+ I SK+M V++EY+++YN A++ LVLF D G+ L++G
Sbjct: 231 YELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGV 290
Query: 2182 GGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQ 2241
GGSGR S+ LA H+ E +C +EL +NY E+ DD++ + ++AG+ FLF+DTQ
Sbjct: 291 GGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQ 350
Query: 2242 ITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRV 2301
I E FLEDINN+LNSG++PNL+ D +Q+ + R + G+ P+ + + + RV
Sbjct: 351 IKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPT-KANLMAAYTGRV 409
Query: 2302 RGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPL----G 2357
R +H+ +CMSP+GE FR R R FPSLVNCCTIDWF +WP EAL SVA L +
Sbjct: 410 RSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELES 469
Query: 2358 NQEIITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXII 2417
+QE I + ++CV +HQ+V E+ R+ Y TP S +
Sbjct: 470 SQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELK 529
Query: 2418 RGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQ 2477
++R+ GL KL T + V M++ + M P+L A +++ +E++K++ A+E +
Sbjct: 530 TAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRN 589
Query: 2478 AVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPA 2537
+V L A+PA++ D+ E++A Q+PP
Sbjct: 590 SVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPP 649
Query: 2538 LVRFVMEPVCILMGVKPD--------------WDSTKKLLADV-NFIGKLADYDKDHIPD 2582
V+ V+E VCI+ G+KP W+ K LL D +F+ L +DKD+I D
Sbjct: 650 GVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGD 709
Query: 2583 ATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAI 2642
+K I+ Y+ +++F P T+ KVSK C S+ WV+A+ Y V + VEPK EA
Sbjct: 710 VVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDD 769
Query: 2643 LKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQAL 2702
L +L ++ + +E +A M + + ++ +L+ + RL RAGK+ L
Sbjct: 770 LGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKVRTLL 829
Score = 57.6 bits (133), Expect = 6e-07
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 2697 KLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAEC 2756
+L L+DEK RW+E+V+ L+ +GD++VA+G +AY G F YR L W+ +
Sbjct: 889 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 948
Query: 2757 SELEIPSSN 2765
+P ++
Sbjct: 949 RSHNVPHTS 957
>AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens cDNA
FLJ43808 fis, clone TESTI4001148, weakly similar to
Dynein beta chain, ciliary. ).
Length = 617
Score = 460 bits (1134), Expect = e-128
Identities = 234/521 (44%), Positives = 321/521 (61%), Gaps = 2/521 (0%)
Query: 982 IVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE-RVDWV 1040
+ AM+S EGE + K ++A G VEDW+ V M + + K A+ Y + RVDW+
Sbjct: 97 VSAMISAEGEVMEFRKIVRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWM 156
Query: 1041 EMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTL 1100
++ VVL SQ+ W V +VF+ + + +Y +K +++L L+
Sbjct: 157 LLYQGMVVLAASQVWWTWEVEDVFH-KAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSK 215
Query: 1101 LFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARMSSAMY 1160
RK ++ IDVHARD + + + +A +F+W +R+YW+ + D R + +
Sbjct: 216 NDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTF 275
Query: 1161 IYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQ 1220
YG+EY+G G LVITPLTDR YL L AL + L DLAK+L +
Sbjct: 276 GYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLL 335
Query: 1221 CVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQ 1280
CVV NC EG+DY+ +G+ FSGLA GAW CFDEFNRID VLSVI+ Q+ TIRNA + +
Sbjct: 336 CVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQL 395
Query: 1281 TRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYS 1340
T F FEG+EI L FITMNPGYAGRTELP+++KALFRP+ ++VPD I E++L+S
Sbjct: 396 TTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFS 455
Query: 1341 EGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTL 1400
EGF +K LAKKM +YKL+ EQLSKQ HYDFG+RA+KSVLVMAG LKR + D E++ L
Sbjct: 456 EGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVL 515
Query: 1401 LCALNDSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQ 1460
+ AL D NLPKF+ D LF G++SDLFPG+ P Y D ++ ++ E + Q
Sbjct: 516 MRALRDMNLPKFVLEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQ 575
Query: 1461 IRKVIQLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRL 1501
+ KV+Q+ ETM+ R M+VGPT GGK+VV++ L T L
Sbjct: 576 VDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTNL 616
Score = 66.9 bits (156), Expect = 1e-09
Identities = 36/88 (40%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 848 MRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSNDELL 907
M + K P+ P + +E L++ K L YL++KR AFPRFFF+S+DELL
Sbjct: 1 MGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELL 60
Query: 908 EILAQTRNPHAVQPHLRKCFDAIAKLEF 935
IL + +P VQ H+ K +D IA L F
Sbjct: 61 SILGSS-DPLCVQEHMIKMYDNIASLRF 87
>AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, heavy
polypeptide 1 protein.
Length = 4646
Score = 390 bits (960), Expect = e-107
Identities = 245/699 (35%), Positives = 367/699 (52%), Gaps = 63/699 (9%)
Query: 982 IVAMLSPEGERVNLGK--GLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMV------ 1033
++ + S EGE V + + +WL VE+ M ++ + + ++ E +
Sbjct: 1673 VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 1732
Query: 1034 ---NERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDL 1090
N + W++ + Q+V+ +QI W++ V + L S LN L
Sbjct: 1733 IDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL 1792
Query: 1091 AALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWE----E 1146
A + L R+ L LIT VH RD +++ + A FEWL +R+Y++ +
Sbjct: 1793 ADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTD 1852
Query: 1147 DIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXX 1206
+ +M++A + YG EYLG LV TPLTDRCYL + AL+ L
Sbjct: 1853 VLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGK 1912
Query: 1207 XXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
L L +VFNC E D++ MGR F GL GAW CFDEFNR++ +LS ++
Sbjct: 1913 TESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVS 1972
Query: 1267 QQLITIRNA----------KVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNL 1316
QQ+ I+ A K + +++K+ A FITMNPGYAGR+ LPDNL
Sbjct: 1973 QQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNL 2032
Query: 1317 KALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRA 1376
K LFR ++M PD LIA+V+LYS+GF +++ LA K+V +KL EQLS Q HYDFG+RA
Sbjct: 2033 KKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRA 2092
Query: 1377 VKSVLVMAGALKRAN---------------------PDQHEEMTLLCALNDSNLPKFLAA 1415
+KSVLV AG +KR + E+ L+ ++ ++ +PK +A
Sbjct: 2093 LKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAE 2152
Query: 1416 DAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKL------QIEICQIRKVIQLHE 1469
D L +LSD+FPGV + + + +K + E L ++ + KV+QL++
Sbjct: 2153 DIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQ 2212
Query: 1470 TMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGEL 1529
+ G+M+VGP+G GK++ VL RL GVEG +I++PK+++ L
Sbjct: 2213 ITQINHGLMMVGPSGSGKSMAWRVLLKALERL--EGVEGV------AHIIDPKAISKDHL 2264
Query: 1530 YGEVNLQTLEWHDGILPLCLRTAVQCLNPD---HQWLICDGPVDAVWIENMNTVLDDNKM 1586
YG ++ T EW DG+ LR + + + QW++ DG VD W+EN+N+VLDDNK+
Sbjct: 2265 YGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKL 2324
Query: 1587 LCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVY 1625
L L N ER+ L P V ++FEV DL A+ ATVSRCGMV+
Sbjct: 2325 LTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVW 2363
Score = 357 bits (878), Expect = 3e-97
Identities = 264/1073 (24%), Positives = 478/1073 (44%), Gaps = 58/1073 (5%)
Query: 1712 LKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKR-QFEEYEEAEYYPQGFNFFDMYMDT 1770
L+ YI ++ +W + G+ R E I+R A P D Y +
Sbjct: 2486 LERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP----IID-YEVS 2540
Query: 1771 RQRKLKVWAEIIPEFIYDCNKPFF-ETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVG 1829
+ W +P+ + +K + +VPT+DTVR+ L L KP++ G G G
Sbjct: 2541 ISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSG 2600
Query: 1830 KTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKR--PRKAIGAP--LGK 1885
KT L +L V V LNFS+ T+ + + + R P + AP LGK
Sbjct: 2601 KTMTLFSALR--ALPDMEV-VGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGK 2657
Query: 1886 KIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGG 1945
+++F D++N+P +D YG Q I +RQ ++ GG Y W + + +C PP
Sbjct: 2658 WLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTD 2717
Query: 1946 -GRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFVPEVSVLGESIVNAAVEV 2004
GR PL+ RF+RH ++Y+ P ++ I+ + + +P + E + A VE
Sbjct: 2718 PGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLR-LIPSLRTYAEPLTAAMVEF 2776
Query: 2005 YLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSP-QGMLRLFYHECLRVFHD 2063
Y + E + HY+++ R++++ ++G+ +A P +G++R++ HE LR+F D
Sbjct: 2777 YT-MSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQD 2835
Query: 2064 RLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNSS-VPKENRTY 2122
RL+ +++ + + +V K+F ++ E + P +L+ ++L+ +P +
Sbjct: 2836 RLVEDEERRWTDENIDTVALKHFP----NIDREKAMSRP--ILYSNWLSKDYIPVDQ--- 2886
Query: 2123 QEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPG 2182
+E+ D K LK + +E ++ LVLF + GH L++G
Sbjct: 2887 EELRDYVKAR--LKVFYEE-----ELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVS 2939
Query: 2183 GSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQI 2242
G+G+ +++ +N +++ R Y +F +DLR + R+G E F+ ++ +
Sbjct: 2940 GAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNV 2999
Query: 2243 TKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVR 2302
FLE +N LL +GEVP LFEGD Y + T C+ A K G+ + +Y +F ++V
Sbjct: 3000 LDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVI 3059
Query: 2303 GKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQE-- 2360
LH+ M+P E + R P+L N C ++WF W EAL V + + ++
Sbjct: 3060 RNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPN 3119
Query: 2361 ---------IITK----------ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXX 2401
+ K I CV +HQ + RL R TP
Sbjct: 3120 YIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDF 3179
Query: 2402 XXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIAL 2461
+ + ++ GL+K+ ET D V + + +R L K A +
Sbjct: 3180 INHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDK 3239
Query: 2462 VERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXX 2521
++++ +Q+ A++ K L PA+
Sbjct: 3240 LKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSI 3299
Query: 2522 XXXDINELKAFQKPPALVRFVMEPVCILMGVK-PDWDSTKKLLADVNFIGKLADYDKDHI 2580
+ E+++ PPA V+ +E +C+L+G DW + ++ NFI + ++ + I
Sbjct: 3300 KKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEI 3359
Query: 2581 PDATLKKIKV-YLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEA 2639
DA +K+K Y+++ +N + V + S C MV W A YA + + VEP + ++
Sbjct: 3360 SDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKL 3419
Query: 2640 AAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLT 2699
K ++ + +EA +A+ +E + E ++AD+ A+++R+ L
Sbjct: 3420 EDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALL 3479
Query: 2700 QALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKW 2752
++L+ E+ RWE++ + Q+ GD ++++ IAY G F R+ L W
Sbjct: 3480 KSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTW 3532
Score = 125 bits (301), Expect = 3e-27
Identities = 77/270 (28%), Positives = 141/270 (52%), Gaps = 14/270 (5%)
Query: 670 LRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFE-ELQAFQHSDELMEVAGQASSEAGLE 728
L++ ALK RHW ++ + LH + + Q+++ +LQ ++ + +V A E LE
Sbjct: 1403 LKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ--KNEAIVKDVLLVAQGEMALE 1460
Query: 729 SLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKS 788
LK++ E+W E ++ +++ ++ G D++ + E HI+++ S+ P
Sbjct: 1461 EFLKQIREVWNTYELDLVNYQNK--CRLIRGWDDLFNKVKE---HINSV-SAMKLSPYYK 1514
Query: 789 RVEE----WAKNLELFAKTLEEWYACQQTWMYLEVIFS-APDIQRQLPNETRLFSIVDKS 843
EE W L + W Q+ W+YLE IF+ + DI+ LP ET+ F +
Sbjct: 1515 VFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTE 1574
Query: 844 WKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSN 903
+ +M+K++K PL M + R ++L +I K L YLE +R +FPRF+F+ +
Sbjct: 1575 FLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGD 1634
Query: 904 DELLEILAQTRNPHAVQPHLRKCFDAIAKL 933
++LLEI+ ++N +Q H +K F ++ +
Sbjct: 1635 EDLLEIIGNSKNVAKLQKHFKKMFAGVSSI 1664
>AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein.
Length = 4658
Score = 390 bits (960), Expect = e-107
Identities = 245/699 (35%), Positives = 367/699 (52%), Gaps = 63/699 (9%)
Query: 982 IVAMLSPEGERVNLGK--GLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMV------ 1033
++ + S EGE V + + +WL VE+ M ++ + + ++ E +
Sbjct: 1685 VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 1744
Query: 1034 ---NERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDL 1090
N + W++ + Q+V+ +QI W++ V + L S LN L
Sbjct: 1745 IDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL 1804
Query: 1091 AALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWE----E 1146
A + L R+ L LIT VH RD +++ + A FEWL +R+Y++ +
Sbjct: 1805 ADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTD 1864
Query: 1147 DIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXX 1206
+ +M++A + YG EYLG LV TPLTDRCYL + AL+ L
Sbjct: 1865 VLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGK 1924
Query: 1207 XXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
L L +VFNC E D++ MGR F GL GAW CFDEFNR++ +LS ++
Sbjct: 1925 TESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVS 1984
Query: 1267 QQLITIRNA----------KVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNL 1316
QQ+ I+ A K + +++K+ A FITMNPGYAGR+ LPDNL
Sbjct: 1985 QQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNL 2044
Query: 1317 KALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRA 1376
K LFR ++M PD LIA+V+LYS+GF +++ LA K+V +KL EQLS Q HYDFG+RA
Sbjct: 2045 KKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRA 2104
Query: 1377 VKSVLVMAGALKRAN---------------------PDQHEEMTLLCALNDSNLPKFLAA 1415
+KSVLV AG +KR + E+ L+ ++ ++ +PK +A
Sbjct: 2105 LKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAE 2164
Query: 1416 DAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKL------QIEICQIRKVIQLHE 1469
D L +LSD+FPGV + + + +K + E L ++ + KV+QL++
Sbjct: 2165 DIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQ 2224
Query: 1470 TMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGEL 1529
+ G+M+VGP+G GK++ VL RL GVEG +I++PK+++ L
Sbjct: 2225 ITQINHGLMMVGPSGSGKSMAWRVLLKALERL--EGVEGV------AHIIDPKAISKDHL 2276
Query: 1530 YGEVNLQTLEWHDGILPLCLRTAVQCLNPD---HQWLICDGPVDAVWIENMNTVLDDNKM 1586
YG ++ T EW DG+ LR + + + QW++ DG VD W+EN+N+VLDDNK+
Sbjct: 2277 YGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKL 2336
Query: 1587 LCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVY 1625
L L N ER+ L P V ++FEV DL A+ ATVSRCGMV+
Sbjct: 2337 LTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVW 2375
Score = 357 bits (878), Expect = 3e-97
Identities = 264/1073 (24%), Positives = 478/1073 (44%), Gaps = 58/1073 (5%)
Query: 1712 LKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKR-QFEEYEEAEYYPQGFNFFDMYMDT 1770
L+ YI ++ +W + G+ R E I+R A P D Y +
Sbjct: 2498 LERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP----IID-YEVS 2552
Query: 1771 RQRKLKVWAEIIPEFIYDCNKPFF-ETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTGVG 1829
+ W +P+ + +K + +VPT+DTVR+ L L KP++ G G G
Sbjct: 2553 ISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSG 2612
Query: 1830 KTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKR--PRKAIGAP--LGK 1885
KT L +L V V LNFS+ T+ + + + R P + AP LGK
Sbjct: 2613 KTMTLFSALR--ALPDMEV-VGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGK 2669
Query: 1886 KIIIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGG 1945
+++F D++N+P +D YG Q I +RQ ++ GG Y W + + +C PP
Sbjct: 2670 WLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTD 2729
Query: 1946 -GRNPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFVPEVSVLGESIVNAAVEV 2004
GR PL+ RF+RH ++Y+ P ++ I+ + + +P + E + A VE
Sbjct: 2730 PGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLR-LIPSLRTYAEPLTAAMVEF 2788
Query: 2005 YLKICAELLPTPAKSHYVFNLRDLSKSMQGVLQAQAAYMRSP-QGMLRLFYHECLRVFHD 2063
Y + E + HY+++ R++++ ++G+ +A P +G++R++ HE LR+F D
Sbjct: 2789 YT-MSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQD 2847
Query: 2064 RLINIQDKSYFYHLMASVCEKNFQTPILSVPDEPIIEHPPLLLFGDFLNSS-VPKENRTY 2122
RL+ +++ + + +V K+F ++ E + P +L+ ++L+ +P +
Sbjct: 2848 RLVEDEERRWTDENIDTVALKHFP----NIDREKAMSRP--ILYSNWLSKDYIPVDQ--- 2898
Query: 2123 QEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPG 2182
+E+ D K LK + +E ++ LVLF + GH L++G
Sbjct: 2899 EELRDYVKAR--LKVFYEE-----ELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVS 2951
Query: 2183 GSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQI 2242
G+G+ +++ +N +++ R Y +F +DLR + R+G E F+ ++ +
Sbjct: 2952 GAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNV 3011
Query: 2243 TKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVR 2302
FLE +N LL +GEVP LFEGD Y + T C+ A K G+ + +Y +F ++V
Sbjct: 3012 LDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVI 3071
Query: 2303 GKLHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQE-- 2360
LH+ M+P E + R P+L N C ++WF W EAL V + + ++
Sbjct: 3072 RNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPN 3131
Query: 2361 ---------IITK----------ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXX 2401
+ K I CV +HQ + RL R TP
Sbjct: 3132 YIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDF 3191
Query: 2402 XXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIAL 2461
+ + ++ GL+K+ ET D V + + +R L K A +
Sbjct: 3192 INHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDK 3251
Query: 2462 VERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXX 2521
++++ +Q+ A++ K L PA+
Sbjct: 3252 LKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSI 3311
Query: 2522 XXXDINELKAFQKPPALVRFVMEPVCILMGVK-PDWDSTKKLLADVNFIGKLADYDKDHI 2580
+ E+++ PPA V+ +E +C+L+G DW + ++ NFI + ++ + I
Sbjct: 3312 KKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEI 3371
Query: 2581 PDATLKKIKV-YLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEA 2639
DA +K+K Y+++ +N + V + S C MV W A YA + + VEP + ++
Sbjct: 3372 SDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKL 3431
Query: 2640 AAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLT 2699
K ++ + +EA +A+ +E + E ++AD+ A+++R+ L
Sbjct: 3432 EDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALL 3491
Query: 2700 QALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKW 2752
++L+ E+ RWE++ + Q+ GD ++++ IAY G F R+ L W
Sbjct: 3492 KSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTW 3544
Score = 125 bits (301), Expect = 3e-27
Identities = 77/270 (28%), Positives = 141/270 (52%), Gaps = 14/270 (5%)
Query: 670 LRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFE-ELQAFQHSDELMEVAGQASSEAGLE 728
L++ ALK RHW ++ + LH + + Q+++ +LQ ++ + +V A E LE
Sbjct: 1415 LKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ--KNEAIVKDVLLVAQGEMALE 1472
Query: 729 SLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKS 788
LK++ E+W E ++ +++ ++ G D++ + E HI+++ S+ P
Sbjct: 1473 EFLKQIREVWNTYELDLVNYQNK--CRLIRGWDDLFNKVKE---HINSV-SAMKLSPYYK 1526
Query: 789 RVEE----WAKNLELFAKTLEEWYACQQTWMYLEVIFS-APDIQRQLPNETRLFSIVDKS 843
EE W L + W Q+ W+YLE IF+ + DI+ LP ET+ F +
Sbjct: 1527 VFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTE 1586
Query: 844 WKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSN 903
+ +M+K++K PL M + R ++L +I K L YLE +R +FPRF+F+ +
Sbjct: 1587 FLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGD 1646
Query: 904 DELLEILAQTRNPHAVQPHLRKCFDAIAKL 933
++LLEI+ ++N +Q H +K F ++ +
Sbjct: 1647 EDLLEIIGNSKNVAKLQKHFKKMFAGVSSI 1676
>BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein.
Length = 1581
Score = 390 bits (959), Expect = e-107
Identities = 193/459 (42%), Positives = 273/459 (59%), Gaps = 2/459 (0%)
Query: 2311 MSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPL--GNQEIITKISKL 2368
MSPVGEAFR RCRMFPSLVNCCTIDWF +WP EALLSV+ + GN+E+ K+ +
Sbjct: 1 MSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLM 60
Query: 2369 CVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQ 2428
CV +H +V M +R Y E+RR +YTTP+S II RDR+ GL
Sbjct: 61 CVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLT 120
Query: 2429 KLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXX 2488
KL ET +V M+ + +EP+L K+ + AL+E+L ++Q++AD+V+ V
Sbjct: 121 KLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKV 180
Query: 2489 XXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCI 2548
L A+PA++ DI+E++ F KPP LV VME + I
Sbjct: 181 KAEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISI 240
Query: 2549 LMGVKPDWDSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKV 2608
L+ KPDW S K+LL D NF+ +L +YDK++I L K++ Y+ + DF P+ V KVSK
Sbjct: 241 LLNAKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKA 300
Query: 2609 CRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMM 2668
C+SM +WV+A+D+Y++V +VVEPK K + A A L MA LR KQ + +E Q+ +
Sbjct: 301 CKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQ 360
Query: 2669 DELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDII 2728
DE +E+ L + L ARL RAGKLT AL DE+ RWEES++ +++ TG++
Sbjct: 361 DEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVF 420
Query: 2729 VASGCIAYFGAFPSHYRRELELKWIAECSELEIPSSNTF 2767
+A+ C+AY+GAF + YR+ L WI +C LEIP +F
Sbjct: 421 IAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSF 459
>BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein.
Length = 551
Score = 380 bits (934), Expect = e-104
Identities = 175/326 (53%), Positives = 234/326 (71%), Gaps = 1/326 (0%)
Query: 1708 DKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEYYPQGFNFFDMY 1767
++ L + F+FCY+W +GGN+ E SF+ I+ QF++ +A P + + ++
Sbjct: 2 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARL-PNSGDLWSIH 60
Query: 1768 MDTRQRKLKVWAEIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTG 1827
MD ++L W IIP F Y+ + PFFE LVPT DTVRYGYL EKLL V+FTG TG
Sbjct: 61 MDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITG 120
Query: 1828 VGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKI 1887
VGK+ IA +LN++ + YVPV LNFSAQTSS RTQE+IE +L+++ + +GAP K+I
Sbjct: 121 VGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRI 180
Query: 1888 IIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGR 1947
+IF+DD+NMP+LD YG+QP IELLRQ+ DFGG YDR+KL+WK+I DV + +CAPPGGGR
Sbjct: 181 VIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGR 240
Query: 1948 NPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFVPEVSVLGESIVNAAVEVYLK 2007
NP+T RF+RHF+ML + P+ ++K IF+AIL G + DF P V SIV A+VE+Y K
Sbjct: 241 NPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNK 300
Query: 2008 ICAELLPTPAKSHYVFNLRDLSKSMQ 2033
+ +LLPTPAKSHYVFNLRDLSK +Q
Sbjct: 301 MSVDLLPTPAKSHYVFNLRDLSKCVQ 326
Score = 188 bits (457), Expect = 3e-46
Identities = 91/189 (48%), Positives = 119/189 (62%)
Query: 2105 LLFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXX 2164
++FGDF+ K +R Y ++PDI K VL++YLD+YN T E+ LV FQD
Sbjct: 344 IIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSR 403
Query: 2165 XXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYM 2224
G+ L+VG GG+G++S+ LA H+ KCL +EL R Y+ FH+DLR +Y
Sbjct: 404 IARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYK 463
Query: 2225 RAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSG 2284
AGV ++ VFLFTDTQI EEFLEDINN+LNSGEVPNLFE D EQV R A + G
Sbjct: 464 MAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVG 523
Query: 2285 VNPSDRDGV 2293
++ +RD V
Sbjct: 524 ISEGNRDEV 532
>AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 380 bits (934), Expect = e-104
Identities = 175/326 (53%), Positives = 234/326 (71%), Gaps = 1/326 (0%)
Query: 1708 DKAALKIYIAHCFIFCYVWCIGGNILEMNRQSFEEVIKRQFEEYEEAEYYPQGFNFFDMY 1767
++ L + F+FCY+W +GGN+ E SF+ I+ QF++ +A P + + ++
Sbjct: 2 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARL-PNSGDLWSIH 60
Query: 1768 MDTRQRKLKVWAEIIPEFIYDCNKPFFETLVPTIDTVRYGYLFEKLLGAGKPVMFTGNTG 1827
MD ++L W IIP F Y+ + PFFE LVPT DTVRYGYL EKLL V+FTG TG
Sbjct: 61 MDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITG 120
Query: 1828 VGKTCIAVEILNRMSLTGYYVPVILNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKI 1887
VGK+ IA +LN++ + YVPV LNFSAQTSS RTQE+IE +L+++ + +GAP K+I
Sbjct: 121 VGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRI 180
Query: 1888 IIFIDDVNMPKLDVYGAQPTIELLRQFLDFGGVYDRDKLYWKDILDVVLSCSCAPPGGGR 1947
+IF+DD+NMP+LD YG+QP IELLRQ+ DFGG YDR+KL+WK+I DV + +CAPPGGGR
Sbjct: 181 VIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGR 240
Query: 1948 NPLTARFVRHFAMLYIAAPNADAMKTIFKAILKGHMEDFVPEVSVLGESIVNAAVEVYLK 2007
NP+T RF+RHF+ML + P+ ++K IF+AIL G + DF P V SIV A+VE+Y K
Sbjct: 241 NPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNK 300
Query: 2008 ICAELLPTPAKSHYVFNLRDLSKSMQ 2033
+ +LLPTPAKSHYVFNLRDLSK +Q
Sbjct: 301 MSVDLLPTPAKSHYVFNLRDLSKCVQ 326
>AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain protein.
Length = 514
Score = 372 bits (916), Expect = e-102
Identities = 199/469 (42%), Positives = 276/469 (58%), Gaps = 10/469 (2%)
Query: 1176 TPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMM 1235
TPLTDRCY+ L AL + + D+ + L VVFNCS+ +D++ +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGL 60
Query: 1236 GRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMF-EGREIKLVR 1294
GR F GLA SGAW CFDEFNRID+ VLSV AQQ+ I K + F+F +G + +
Sbjct: 61 GRIFKGLAQSGAWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNP 120
Query: 1295 TCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMV 1354
F+TMNPGYAGR ELP+NLK FR ++MMVPD +I V L S GF + LA+K
Sbjct: 121 EFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFF 180
Query: 1355 QMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLA 1414
+YKL EQLSKQ HYDFG+R + SVL GA KRANP E ++ L D NL K +
Sbjct: 181 TLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLID 240
Query: 1415 ADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVIQLHETMIVR 1474
D LF ++ +LFP + L Y +E I + + L KVIQ +T VR
Sbjct: 241 EDEPLFLSLIENLFPNILLDKAGYPELEAAINRQVEKAGLINHPPWKLKVIQQTKTQRVR 300
Query: 1475 WGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLTIGELYGEVN 1534
G+M +GP+G GKT +H L T + G +P R+ MNPK++T +++G ++
Sbjct: 301 HGMMTLGPSGAGKTTCIHTLMRAMT---DCG------KPHREMRMNPKAITAPQMFGRLD 351
Query: 1535 LQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIENMNTVLDDNKMLCLSNSER 1594
+ T +W DGI R ++ +H W+I DGPVDA+WIEN+N+VLDDNK L L+N +R
Sbjct: 352 VATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDR 411
Query: 1595 IKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRSWLQE 1643
I + P ++FE ++ ASPATVSR GMV++ + + + P + +L++
Sbjct: 412 IPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKK 460
>BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein.
Length = 314
Score = 286 bits (702), Expect = 7e-76
Identities = 148/296 (50%), Positives = 195/296 (65%), Gaps = 2/296 (0%)
Query: 1346 SKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALN 1405
S+ LA+K+V Y+L SEQLS Q HYD+GMRAVKSVL AG LK P+++E + LL AL
Sbjct: 2 SRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALL 61
Query: 1406 DSNLPKFLAADAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVI 1465
D NL KFLA D LF GI+SDLFPGV LP DY V V+ + + KLQ I K+I
Sbjct: 62 DVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKII 121
Query: 1466 QLHETMIVRWGVMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQYQPVRKYIMNPKSLT 1525
Q++E M+VR G M+VG GGKT VL L+ + V I+NPK++T
Sbjct: 122 QIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLH--AANQMEEFAVEYKIINPKAIT 179
Query: 1526 IGELYGEVNLQTLEWHDGILPLCLRTAVQCLNPDHQWLICDGPVDAVWIENMNTVLDDNK 1585
+G+LYG + + EW DG+L R L+ D +W+I DGPVDA+WIENMNTVLDDNK
Sbjct: 180 MGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNK 239
Query: 1586 MLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVYIDPNEMGYLPFVRSWL 1641
LCL + E I++ + ++FE ADL QASPATVSRCGM+Y++P+++G+ P S++
Sbjct: 240 KLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYM 295
>AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy
chain 14 protein.
Length = 234
Score = 257 bits (630), Expect = 4e-67
Identities = 121/223 (54%), Positives = 165/223 (73%), Gaps = 2/223 (0%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAKSL CVVFNC E LDYK++ +FF GL SGAW CFDEFN ID+EVLSVIA Q++T
Sbjct: 12 DLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILT 71
Query: 1272 IRNAKVAKQTRFMF--EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPD 1329
I+ AK R++F EG+EI++ +CA FITMNP Y G ELPDNLK+LFRP++MMVP
Sbjct: 72 IKAAKDNYSARYLFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPH 131
Query: 1330 YALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRAVKSVLVMAGALKR 1389
Y +IAE+IL+S GF+S+ L+ K+ +Y+L+ +QLS+QDHY+FG+R++K VL+MAG KR
Sbjct: 132 YQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKR 191
Query: 1390 ANPDQHEEMTLLCALNDSNLPKFLAADAILFAGILSDLFPGVS 1432
+ E + ++ A+ +++LPK D LF I+ D+FP V+
Sbjct: 192 DLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVT 234
>AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein.
Length = 1270
Score = 252 bits (617), Expect = 1e-65
Identities = 133/420 (31%), Positives = 233/420 (55%), Gaps = 6/420 (1%)
Query: 539 YDEKSDLEKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQL 598
+ + D+++ ++ L KL + + +Q ++ F P+ Q + + +
Sbjct: 704 FGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLR 763
Query: 599 LWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSN----TIVPKCK 654
L++ + E++ +++W + P++ ++ D+++ +Y + +L+K + + K +
Sbjct: 764 LYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR 823
Query: 655 ELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDEL 714
++ K+ +P+I + NP L+PRHW + I+ P + F ++ + D
Sbjct: 824 SKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRF 883
Query: 715 MEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHI 774
++ AS E LE ++K+ W A+EF + +++ ++L +DEIQ LD+ I
Sbjct: 884 EGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRET-GTFILASVDEIQMLLDDHIIKT 942
Query: 775 STILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSAPDIQRQLPNET 834
T+ S P + ++ EW L L + L+EW Q TW+YLE IFS+PDI Q+P E
Sbjct: 943 QTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEG 1002
Query: 835 RLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVA 894
R F+ VDK+W+DIMR + + + T ++ E ++NE+L+ I+K L YLE KR+
Sbjct: 1003 RRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLF 1062
Query: 895 FPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFGVKFPESEMEIAEDGTLVE 954
FPRFFFLSNDELLEIL++T++P VQPHL+KCF+ IAK+EF + M+ +E G +VE
Sbjct: 1063 FPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSE-GEVVE 1121
Score = 125 bits (302), Expect = 2e-27
Identities = 71/170 (41%), Positives = 95/170 (55%), Gaps = 8/170 (4%)
Query: 979 TTDIVAMLSPEGERVNLGKGL---KARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE 1035
T DI M S EGE V L + + KARG VE WL ++E M S+ + A Y E
Sbjct: 1106 TLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYE 1165
Query: 1036 RVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTR 1095
R++WV P Q VL VSQI W K V IP+ I L Y K C ++D+ L R
Sbjct: 1166 RINWVRDWPGQTVLCVSQIFWTKEVQTA----IPMGIKA-LEQYLKTCNRQIDDIVTLVR 1220
Query: 1096 KDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWE 1145
L++ R L AL+ +DVHARD +S +V+K++ +DFEWL +RYYW+
Sbjct: 1221 GKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQ 1270
>Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy chain
protein.
Length = 177
Score = 245 bits (600), Expect = 2e-63
Identities = 112/164 (68%), Positives = 134/164 (81%)
Query: 1213 LAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITI 1272
LAK+LA QCVVFNCS+GLDYK MG+FF GLA +GAW CFDEFNRI++EVLSV+AQQ+++I
Sbjct: 14 LAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSI 73
Query: 1273 RNAKVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYAL 1332
+ A + K F+FEG E+ L TCA FITMNPGYAGR ELPDNLKALFR ++MMVPDYAL
Sbjct: 74 QQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYAL 133
Query: 1333 IAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRA 1376
I E+ LYS GF S+ LA+K+V Y+L SEQLS Q HYDFG+ A
Sbjct: 134 IGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDFGLHA 177
>AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein.
Length = 582
Score = 245 bits (600), Expect = 2e-63
Identities = 137/449 (30%), Positives = 222/449 (49%), Gaps = 4/449 (0%)
Query: 2323 RMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQE----IITKISKLCVTMHQNVDM 2378
R++PS+++ CTIDW+ +WP EALL VA+ L+ N E + K++ CV +H+++
Sbjct: 1 RVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKD 60
Query: 2379 MTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVG 2438
+ + + E R++YTTP+S + RDR GL + E +V
Sbjct: 61 LNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVT 120
Query: 2439 VMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXX 2498
M++++ + P + +K E+ L+E+L+ + + ++V+ V
Sbjct: 121 EMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQ 180
Query: 2499 XXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILMGVKPDWDS 2558
L +PA + D+ EL+ + +PP LV VM VCIL+ KP+W +
Sbjct: 181 KTANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPNWAT 240
Query: 2559 TKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQA 2618
K LL++ F+ KL + DKD IPD K+K +T DFNP + VS C S+ WV A
Sbjct: 241 AKLLLSETGFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIA 300
Query: 2619 IDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDER 2678
++ Y +V +VV PK ++ EA +LK L KQ+ ++ +E L + K E+
Sbjct: 301 LNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEK 360
Query: 2679 LKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFG 2738
L +A+ R A L L DEKTRW+E++ +L GDI++++ CI Y G
Sbjct: 361 QLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSG 420
Query: 2739 AFPSHYRRELELKWIAECSELEIPSSNTF 2767
+R+ + KW C E I S+ F
Sbjct: 421 ILTPEFRQLIVNKWETFCIENGISLSSKF 449
>Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy chain
protein.
Length = 169
Score = 230 bits (563), Expect = 5e-59
Identities = 105/162 (64%), Positives = 131/162 (80%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAK++A QCVVF+C +GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++T
Sbjct: 8 DLAKAVAKQCVVFDCPDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILT 67
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPDYA 1331
I+ A MFEG E+KL TCA FITMNPGYAGR+ELPDNLKALFR ++MMVPDYA
Sbjct: 68 IQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYA 127
Query: 1332 LIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFG 1373
+IAE++LYS GF +++ L+ K+V Y+L SEQLS Q HYD+G
Sbjct: 128 MIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYG 169
>AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein.
Length = 1659
Score = 227 bits (556), Expect = 3e-58
Identities = 154/597 (25%), Positives = 272/597 (45%), Gaps = 28/597 (4%)
Query: 2187 RSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEE 2246
R + +AG+V+ + L R+Y+T +DL+++Y AG + F+FTD +I E
Sbjct: 2 RLASFIAGYVS----FQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDES 57
Query: 2247 FLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVN--PSDRDGVYYFFINRVRGK 2304
FLE +NN+L+SGEV NLF D +++ + + K P++ + ++ +F++RVR
Sbjct: 58 FLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTN-ENLHDYFMSRVRQN 116
Query: 2305 LHLCICMSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLG---NQEI 2361
LH+ +C SPVGE FR R FP+L++ CTIDWF++WP +AL++V+ L + EI
Sbjct: 117 LHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEI 176
Query: 2362 ITKISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRD 2421
++ + + V + RR + TP S + +
Sbjct: 177 KKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLAN 236
Query: 2422 RISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMX 2481
R++ GL+KL E + V + +++ E L ++ +++ + ++ +AA++VK V
Sbjct: 237 RMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQK 296
Query: 2482 XXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRF 2541
L A PA+E DI ++ +PP L+
Sbjct: 297 VKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMR 356
Query: 2542 VMEPVCILMGVK--------------PDWDSTKKLLADVNFIGKLADYDKDHIPDATLKK 2587
+M+ V +L K P W + KL+ NF+ L + KD I + ++
Sbjct: 357 IMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEF 416
Query: 2588 IKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVM 2647
+ Y D+N +T +V + W +A+ + + + V P LK + ++
Sbjct: 417 LSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLP--LKANLVVQENRHLL 474
Query: 2648 AV--LRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADE 2705
A+ L+ Q E++ +A+L + E + E+ L D + ++ A L LA E
Sbjct: 475 AMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGE 534
Query: 2706 KTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAECSELEIP 2762
K RW E + Q GD+++A+ ++Y G F +R L W E +IP
Sbjct: 535 KERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIP 591
>Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 179
Score = 219 bits (535), Expect = 1e-55
Identities = 106/167 (63%), Positives = 131/167 (78%), Gaps = 2/167 (1%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAK+LA+QCVVFNCS+GLDY MG+FF GLA+SGAW CFDEFNRI++EVLSV+AQQ++
Sbjct: 13 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILC 72
Query: 1272 IRNAKVAKQTRFMF-EGREIKL-VRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPD 1329
I+ A K F F EG E+KL ITMNPGYAG +ELPDNLK LFR ++MMVP+
Sbjct: 73 IQRAIQQKLVVFWFLEGTELKLNPGIVFVAITMNPGYAGHSELPDNLKVLFRTVAMMVPN 132
Query: 1330 YALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFGMRA 1376
YALIAE+ LYS GF +++ L+ K+V Y+L SEQLS Q HYD+G+RA
Sbjct: 133 YALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGLRA 179
>AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens cDNA
FLJ38262 fis, clone FCBBF3001594, moderately similar to
Chlamydomonas reinhardtii dhc1 gene for 1-alpha dynein ).
Length = 828
Score = 202 bits (493), Expect = 1e-50
Identities = 134/461 (29%), Positives = 207/461 (44%), Gaps = 4/461 (0%)
Query: 2311 MSPVGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCL--QPLGNQEIITKISKL 2368
MSPVG+ R CR FP +VN IDWF WPP+AL +VA L P+ E I + K
Sbjct: 1 MSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKH 60
Query: 2369 CVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQ 2428
V +HQ+VD + + ++RR Y TP + I R+ GL
Sbjct: 61 VVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLD 120
Query: 2429 KLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXX 2488
KL E + + Q++ E + +LA K+A AL+E + + A+E K+
Sbjct: 121 KLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEE 180
Query: 2489 XXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCI 2548
LA MP +E D+ E+++F KPP V+ V E + I
Sbjct: 181 QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILI 240
Query: 2549 LMGVKP-DWDSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSK 2607
+ G K +W + K +++D NF+ L + D D I + +K IK L + + + VSK
Sbjct: 241 MKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSK 300
Query: 2608 VCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKM 2667
M+ +V+A+ Y VFR ++PK K L Q E+ AI+ +L +
Sbjct: 301 AGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETL 360
Query: 2668 MDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDI 2727
+ + E+ KLQ + ++ RL A KL L E RW + + GD
Sbjct: 361 GAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDC 420
Query: 2728 IVASGCIAYFGAFPSHYRRELELK-WIAECSELEIPSSNTF 2767
++ + ++Y GAF +R E+ + W + E EIP S F
Sbjct: 421 LLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPF 461
>AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein.
Length = 224
Score = 188 bits (457), Expect = 3e-46
Identities = 91/189 (48%), Positives = 119/189 (62%)
Query: 2105 LLFGDFLNSSVPKENRTYQEIPDISKLMIVLKEYLDEYNSTARAEMHLVLFQDXXXXXXX 2164
++FGDF+ K +R Y ++PDI K VL++YLD+YN T E+ LV FQD
Sbjct: 17 IIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSR 76
Query: 2165 XXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRNYDTPEFHDDLRMMYM 2224
G+ L+VG GG+G++S+ LA H+ KCL +EL R Y+ FH+DLR +Y
Sbjct: 77 IARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYK 136
Query: 2225 RAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSYEQVQTGCRTEAAKSG 2284
AGV ++ VFLFTDTQI EEFLEDINN+LNSGEVPNLFE D EQV R A + G
Sbjct: 137 MAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVG 196
Query: 2285 VNPSDRDGV 2293
++ +RD V
Sbjct: 197 ISEGNRDEV 205
>AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 184 bits (449), Expect = 3e-45
Identities = 87/143 (60%), Positives = 103/143 (72%)
Query: 1162 YGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQC 1221
YG EYLG LVITPLTDRCY LMGAL+L+L DLAK+LA QC
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQC 60
Query: 1222 VVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQT 1281
VVFNCS+GLDYK MG+FF GLA +GAW CFDEFNRI++EVLSV+AQQ+++I+ A + K
Sbjct: 61 VVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLK 120
Query: 1282 RFMFEGREIKLVRTCAAFITMNP 1304
F+FEG E+ L TCA FITMNP
Sbjct: 121 TFIFEGTELSLNPTCAVFITMNP 143
>AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 182 bits (442), Expect = 2e-44
Identities = 88/143 (61%), Positives = 100/143 (69%)
Query: 1162 YGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQC 1221
YG EYLG G LVITPLTDRCYL L GAL L DL K+LAIQ
Sbjct: 1 YGFEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQT 60
Query: 1222 VVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQT 1281
VVFNCS+ LD+ MG+FF GLA++GAW CFDEFNRIDIEVLSV+AQQ+ TI+ A+ +
Sbjct: 61 VVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVE 120
Query: 1282 RFMFEGREIKLVRTCAAFITMNP 1304
RFMFEG EI LV +CA FITMNP
Sbjct: 121 RFMFEGVEIPLVPSCAVFITMNP 143
>AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens cDNA
FLJ46675 fis, clone TRACH3009701, weakly similar to Homo
sapiens dynein, axonemal, heavy polypeptide 9 (DNAH9). ).
Length = 901
Score = 181 bits (440), Expect = 4e-44
Identities = 93/247 (37%), Positives = 146/247 (59%), Gaps = 7/247 (2%)
Query: 2525 DINELKAFQKPPALVRFVMEPVCILMGVKPDWDSTKKLLADVNFIGKLADYDKDHIPDAT 2584
DI E+K++ +PPA V VM+ V IL G +P W K+ L + NFI L ++DKD+I D
Sbjct: 47 DIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKV 106
Query: 2585 LKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILK 2644
LKKI Y DF PD + +VS +S+ +WV+A+++Y +++RVVEPK ++ A A L+
Sbjct: 107 LKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLR 166
Query: 2645 SVMAVLRAKQKEVEAIEAQLA---KMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQA 2701
A L Q+++ + +L K DE ++E K +++L +L RAG L
Sbjct: 167 EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMEL---KLERAGMLVSG 223
Query: 2702 LADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELK-WIAECSELE 2760
LA EK RWEE+V+ + L GD ++A+ ++Y G F ++YR E+ + WI + EL+
Sbjct: 224 LAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQ 283
Query: 2761 IPSSNTF 2767
+P S +F
Sbjct: 284 VPCSPSF 290
>AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 180 bits (439), Expect = 5e-44
Identities = 85/93 (91%), Positives = 88/93 (94%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAK+LAIQCVVFNCS+GLD KMMGRFFSGLA SGAWCCFDEFNRIDIEVLSVIAQQLIT
Sbjct: 9 DLAKALAIQCVVFNCSDGLDCKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLIT 68
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNP 1304
IRNAK AK +RFMFEGREIKLV TCAAFITMNP
Sbjct: 69 IRNAKAAKLSRFMFEGREIKLVMTCAAFITMNP 101
>U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heavy
chain protein.
Length = 197
Score = 180 bits (437), Expect = 9e-44
Identities = 90/182 (49%), Positives = 111/182 (60%), Gaps = 1/182 (0%)
Query: 1075 GLLSYEKKCISDLNDLAALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDF 1134
GL Y K+ + LN++ L R L+ R L AL+TIDV ARD + M++ V DF
Sbjct: 15 GLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVRARDVVMDMIKMGVSHDTDF 74
Query: 1135 EWLKMIRYYWEEDIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDL 1194
WL +RYYWE + + V + M Y +EYLG LVITPLTDRCY L+GA L+L
Sbjct: 75 LWLAQLRYYWENE-NARVRIIQLPMLKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNL 133
Query: 1195 XXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEF 1254
DLAK+LA+QCVVFNCS+GLDY MG+FF GLA+SGAW CFDEF
Sbjct: 134 GGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEF 193
Query: 1255 NR 1256
NR
Sbjct: 194 NR 195
>AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein.
Length = 1685
Score = 175 bits (427), Expect = 1e-42
Identities = 126/609 (20%), Positives = 240/609 (39%), Gaps = 10/609 (1%)
Query: 2150 MHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLAGHVNECKCLGMELKRN 2209
+ ++LF + G L+ G G GRR++ +L H++ ++ R
Sbjct: 3 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 62
Query: 2210 YDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINNLLNSGEVPNLFEGDSY 2269
Y+ +F +DL+ + AG+ + V L D Q FLE IN+LL+SGEVP L+ +
Sbjct: 63 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 122
Query: 2270 EQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLV 2329
E + + +A++ G V+ +F R++ LH+ + M F C P+L
Sbjct: 123 EPLLLPLKDQASQDGF----FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALH 178
Query: 2330 NCCTIDWFTKWPPEALLSVAHQCLQPLGNQEIITKISKLCVTMHQNVD---MMTDRLYME 2386
C + W W ++ + G E + +VD + + L E
Sbjct: 179 KKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHE 238
Query: 2387 MRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKLYETYDVVGVMEQQVRE 2446
+ + TPS +++ + + G+ KL E +V + ++ E
Sbjct: 239 SCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGE 298
Query: 2447 MEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXXXXXXXXXXXXXXXLAL 2506
+L K E+ A ++ + + + A E K + L
Sbjct: 299 QSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKE 358
Query: 2507 AMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILMGV-KPDWDSTKKLLAD 2565
P + ++E+++ + PP ++R ++E V LMG+ W S K LA
Sbjct: 359 VQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAK 418
Query: 2566 VNFIGKLADYDKDHIPDATLKKIK--VYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYA 2623
+A +D +I + ++ ++ F+P + S + WV+A Y+
Sbjct: 419 RGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYS 478
Query: 2624 KVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQA 2683
V + P + + LK R ++ + ++ +++++ ++ ++ E KL+A
Sbjct: 479 HVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEA 538
Query: 2684 DVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSH 2743
+V A + A L L E RW V T++L +A+ I Y A P
Sbjct: 539 EVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPES 598
Query: 2744 YRRELELKW 2752
R+ +W
Sbjct: 599 LRKTCLEEW 607
>BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein
protein.
Length = 1732
Score = 175 bits (426), Expect = 2e-42
Identities = 129/625 (20%), Positives = 246/625 (39%), Gaps = 11/625 (1%)
Query: 2134 VLKEYLDEYNSTARAEMHLVLFQDXXXXXXXXXXXXXXXXGHCLMVGPGGSGRRSVATLA 2193
V+K+ L Y + + ++LF + G L+ G G GRR++ +L
Sbjct: 28 VIKKGLIHYGRDNQ-NLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLV 86
Query: 2194 GHVNECKCLGMELKRNYDTPEFHDDLRMMYMRAGVNCEDTVFLFTDTQITKEEFLEDINN 2253
H++ ++ R Y+ +F +DL+ + AG+ + V L D Q FLE IN+
Sbjct: 87 SHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINS 146
Query: 2254 LLNSGEVPNLFEGDSYEQVQTGCRTEAAKSGVNPSDRDGVYYFFINRVRGKLHLCICMSP 2313
LL+SGEVP L+ + E + + +A++ G V+ +F R++ LH+ + M
Sbjct: 147 LLSSGEVPGLYTLEELEPLLLPLKDQASQDGF----FGPVFNYFTYRIQQNLHIVLIMDS 202
Query: 2314 VGEAFRRRCRMFPSLVNCCTIDWFTKWPPEALLSVAHQCLQPLGNQEIITKISKLCVTMH 2373
F C P+L C + W W ++ + G E +
Sbjct: 203 ANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKK 262
Query: 2374 QNVD---MMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRISCGLQKL 2430
+VD + + L E + + TPS +++ + + G+ KL
Sbjct: 263 NSVDPDFLKSFLLIHESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKL 322
Query: 2431 YETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXXXXXXXX 2490
E +V + ++ E +L K E+ A ++ + + + A E K +
Sbjct: 323 NEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEV 382
Query: 2491 XXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVMEPVCILM 2550
L P + ++E+++ + PP ++R ++E V LM
Sbjct: 383 VKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLM 442
Query: 2551 GV-KPDWDSTKKLLADVNFIGKLADYDKDHIPDATLKKIK--VYLTHKDFNPDTVVKVSK 2607
G+ W S K LA +A +D +I + ++ ++ F+P + S
Sbjct: 443 GIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRAST 502
Query: 2608 VCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKM 2667
+ WV+ Y+ V + P + + LK R ++ + ++ +++++
Sbjct: 503 AAAPLAAWVKVNIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSEL 562
Query: 2668 MDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGDI 2727
++ ++ E KL+A+V A + A L L E RW V T++L
Sbjct: 563 KEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRA 622
Query: 2728 IVASGCIAYFGAFPSHYRRELELKW 2752
+A+ I Y A P R+ +W
Sbjct: 623 QLAAAFITYLSAAPESLRKTCLEEW 647
>AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 173 bits (420), Expect = 1e-41
Identities = 84/143 (58%), Positives = 96/143 (67%)
Query: 1162 YGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQC 1221
YG EYLG LVITPLTDRCY L GAL L L DLAK++A QC
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 60
Query: 1222 VVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQT 1281
VVFNCS+GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++TI+ A
Sbjct: 61 VVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD 120
Query: 1282 RFMFEGREIKLVRTCAAFITMNP 1304
MFEG E+KL TCA FITMNP
Sbjct: 121 ILMFEGTELKLDPTCAVFITMNP 143
>Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy chain
protein.
Length = 179
Score = 172 bits (418), Expect = 2e-41
Identities = 84/160 (52%), Positives = 110/160 (68%), Gaps = 3/160 (1%)
Query: 1217 LAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAK 1276
L Q +VFNC EG+D K MGR F GL GAW CFDEFNR++ VLS ++ Q+ TI++A
Sbjct: 18 LGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDAL 77
Query: 1277 VAKQTRFMFEGREIKLVRTCAAFITMNP---GYAGRTELPDNLKALFRPISMMVPDYALI 1333
+T G+E+++ FITMNP GY GR +LPDNLK LFRP++M PD LI
Sbjct: 78 KNHRTVCELLGKEVEVNSHSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELI 137
Query: 1334 AEVILYSEGFESSKGLAKKMVQMYKLSSEQLSKQDHYDFG 1373
AEVILYSEGF+ +K L++K+V ++ LS E L+ Q HYD+G
Sbjct: 138 AEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDYG 177
>U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy chain
1 (DHC1) protein.
Length = 897
Score = 153 bits (371), Expect = 9e-36
Identities = 105/354 (29%), Positives = 163/354 (46%), Gaps = 25/354 (7%)
Query: 982 IVAMLSPEGERVNLGK--GLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMV------ 1033
++ + S EGE V + + +WL VE+ M ++ + + ++ E +
Sbjct: 544 VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 603
Query: 1034 ---NERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDL 1090
N + W++ + Q+V+ +QI W++ V + S LN L
Sbjct: 604 IDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPSDSVLSNVEVTLNVL 663
Query: 1091 AALTRKDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWE----E 1146
A + L R+ L LIT VH RD +++ + A FEWL +R+Y++ +
Sbjct: 664 ADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTD 723
Query: 1147 DIDNCVARMSSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXX 1206
+ +M++A + YG EYLG LV TPLTDRCYL + AL+ L
Sbjct: 724 VLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGK 783
Query: 1207 XXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
L L +VFNC E D++ GR F GL GAW CFDEFNR++ +LS ++
Sbjct: 784 TESVKALGHQLGRFVLVFNCDETFDFQARGRIFVGLCQVGAWGCFDEFNRLEERMLSAVS 843
Query: 1267 QQLITIRNA----------KVAKQTRFMFEGREIKLVRTCAAFITMNPGYAGRT 1310
QQ+ I+ A K + +++K+ A FITMNPGYAG +
Sbjct: 844 QQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGNS 897
Score = 125 bits (301), Expect = 3e-27
Identities = 77/270 (28%), Positives = 141/270 (52%), Gaps = 14/270 (5%)
Query: 670 LRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFE-ELQAFQHSDELMEVAGQASSEAGLE 728
L++ ALK RHW ++ + LH + + Q+++ +LQ ++ + +V A E LE
Sbjct: 274 LKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ--KNEAIVKDVLLVAQGEMALE 331
Query: 729 SLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQASLDESNIHISTILSSRNCGPIKS 788
LK++ E+W E ++ +++ ++ G D++ + E HI+++ S+ P
Sbjct: 332 EFLKQIREVWNTYELDLVNYQNK--CRLIRGWDDLFNKVKE---HINSV-SAMKLSPYYK 385
Query: 789 RVEE----WAKNLELFAKTLEEWYACQQTWMYLEVIFS-APDIQRQLPNETRLFSIVDKS 843
EE W L + W Q+ W+YLE IF+ + DI+ LP ET+ F +
Sbjct: 386 VFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTE 445
Query: 844 WKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLEAYLETKRVAFPRFFFLSN 903
+ +M+K++K PL M + R ++L +I K L YLE +R +FPRF+F+ +
Sbjct: 446 FLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGD 505
Query: 904 DELLEILAQTRNPHAVQPHLRKCFDAIAKL 933
++LLEI+ ++N +Q H +K F ++ +
Sbjct: 506 EDLLEIIGNSKNVAKLQKHFKKMFAGVSSI 535
>AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1031
Score = 145 bits (351), Expect = 2e-33
Identities = 100/398 (25%), Positives = 174/398 (43%), Gaps = 9/398 (2%)
Query: 2365 ISKLCVTMHQNVDMMTDRLYMEMRRYFYTTPSSXXXXXXXXXXXXXXXXXXIIRGRDRIS 2424
IS +H V+ M+ R Y RR+ YTTP S + ++R+
Sbjct: 7 ISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLV 66
Query: 2425 CGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAVMXXXX 2484
G+QKL T VG ++ ++ E L + ++ AL+ ++ ++ + K
Sbjct: 67 NGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEER 126
Query: 2485 XXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALVRFVME 2544
L A PA+ +++ELKAF PP V V
Sbjct: 127 KVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTA 186
Query: 2545 PVCILMG----VKPD--WDSTKKLLADVN-FIGKLADYDKDHIPDATLKKIKV-YLTHKD 2596
V +L+ V D W + K + V+ F+ L +YDK+HIP+ LK + YL +
Sbjct: 187 AVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPE 246
Query: 2597 FNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKE 2656
FNP+ + S + WV I + +V+ VEPK +A L + L A +K+
Sbjct: 247 FNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKK 306
Query: 2657 VEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKAA 2716
+ ++ L+++ + E+++ Q +V+ + A +L + L +K RW +S+K+
Sbjct: 307 LVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSF 366
Query: 2717 TQQLHCTTGDIIVASGCIAYFGAFPSHYRREL-ELKWI 2753
Q GD+++ + ++Y G F YR+EL KW+
Sbjct: 367 EAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWV 404
>AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein.
Length = 1457
Score = 142 bits (345), Expect = 1e-32
Identities = 84/298 (28%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 2420 RDRISCGLQKLYETYDVVGVMEQQVREMEPILARKAAESIALVERLKIEQKAADEVKQAV 2479
++R+ GL KL T + V M++ + M P+L A +++ +E++K++ A+E + +V
Sbjct: 25 KNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSV 84
Query: 2480 MXXXXXXXXXXXXXXXXXXXXXXXLALAMPAMEXXXXXXXXXXXXDINELKAFQKPPALV 2539
L A+PA++ D+ E++A Q+PP V
Sbjct: 85 QTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGV 144
Query: 2540 RFVMEPVCILMGVKPD--------------WDSTKKLLADV-NFIGKLADYDKDHIPDAT 2584
+ V+E VCI+ G+KP W+ K LL D +F+ L +DKD+I D
Sbjct: 145 KLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVV 204
Query: 2585 LKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILK 2644
+K I+ Y+ +++F P T+ KVSK C S+ WV+A+ Y V + VEPK EA L
Sbjct: 205 IKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLG 264
Query: 2645 SVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQAL 2702
+L ++ + +E +A M + + ++ +L+ + RL RAGK+ L
Sbjct: 265 VTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKVRTLL 322
Score = 57.6 bits (133), Expect = 6e-07
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 2697 KLTQALADEKTRWEESVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKWIAEC 2756
+L L+DEK RW+E+V+ L+ +GD++VA+G +AY G F YR L W+ +
Sbjct: 382 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 441
Query: 2757 SELEIPSSN 2765
+P ++
Sbjct: 442 RSHNVPHTS 450
>AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein.
Length = 1007
Score = 141 bits (342), Expect = 3e-32
Identities = 193/821 (23%), Positives = 341/821 (41%), Gaps = 80/821 (9%)
Query: 877 LDQIMKCLEAYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFG 936
L+ I+ LE+ L FPR FFLS+ EL+ +LA Q +R+CF + + F
Sbjct: 27 LEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 86
Query: 937 VKFPESEMEIAEDGTLVEKEMSFQTRDMLQA--KLAKTASPEDLTTDIVAMLSPEGERVN 994
P E + + + + +L A + K P L D+ L+ + +
Sbjct: 87 -SCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLR 145
Query: 995 LGKGLKARGNVEDWLGK---VEEAMFASVKRCMKFALKEYMVNERVDWVEMHPNQVVLTV 1051
L +G V L + + EA+ K+ K L+ Y V +D V+ P Q VL
Sbjct: 146 LALVHMLQGCVAARLARGPSLGEALKQLPKQ-NKLYLQLY-VQHWIDLVQAFPWQCVLVA 203
Query: 1052 SQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTRKDLTLLFRK--VLCAL 1109
+++W + E L + + + + ++ + A R+ +L AL
Sbjct: 204 EEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSAL 263
Query: 1110 ITIDVHARDTISHMVEKH-VQKANDFEWLKMIRYYWE-------------EDIDNCVARM 1155
+ + V RD I+ ++E+H V DF W++ ++Y+ + I + +
Sbjct: 264 LVMAVTHRD-IAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSL 322
Query: 1156 SSAM---------YIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXX 1206
S A ++Y +EYLG + + L +R L L+ AL+
Sbjct: 323 SPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGK 382
Query: 1207 XXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
LA++L Q V+ CS ++ + + + +G GAW ++ +++ +LS +
Sbjct: 383 RAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALG 442
Query: 1267 QQLITIRNA-----KVAKQTRFMFEGREIKLVRTC---AAFITMNPGY-------AGRTE 1311
Q+L + + + A + + + +L+ + +++ GY A +
Sbjct: 443 QRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSA 502
Query: 1312 LPDNLKALFRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLS------ 1365
+P NL L RP+++ +PD +AE+ L G + +A ++ + + L E +S
Sbjct: 503 VPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCR 562
Query: 1366 ----KQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAIL-F 1420
KQ D +R + K + EE LL AL S L L +
Sbjct: 563 LPLLKQILEDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHNL 621
Query: 1421 AGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVI----QLHETMIVRWG 1476
G+L LFP S + + ++K +++E Q+ + ++ QL + + G
Sbjct: 622 RGLLCALFPSASQVLAE-PMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 680
Query: 1477 VMLVGPTGGGKTVVLHVLGDTYTRLYENGVEGSQ-YQPVRKYIMNPKSLTIGELYGEVNL 1535
++L+GP G GKT H L RL +Q QPV + P L+ E G L
Sbjct: 681 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGW--L 738
Query: 1536 QTLEWHDGILPLCLRTAVQCLNPDHQ-----------WLICDGPVDAVWIENMNTVLDDN 1584
+ WH GI P LR A QC N + W+ICDG + W++++ +L +
Sbjct: 739 EGSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 798
Query: 1585 KMLCLSNSERIKLTPYVHMVFEVADLAQASPATVSRCGMVY 1625
L L + ++I P ++ EVAD SP V C +V+
Sbjct: 799 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVW 839
>U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isotype 1B
protein.
Length = 161
Score = 140 bits (340), Expect = 5e-32
Identities = 74/161 (45%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Query: 1182 CYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGRFFSG 1241
CYL L A+++ L L L Q +VFNC EG+D K MGR F G
Sbjct: 1 CYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVG 60
Query: 1242 LATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMFEGREIKLVRTCAAFIT 1301
L GAW CFDEFNR++ VLS ++ Q+ TI++A +T G+E+++ FIT
Sbjct: 61 LVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFIT 120
Query: 1302 MNP---GYAGRTELPDNLKALFRPISMMVPDYALIAEVILY 1339
MNP GY GR +LPDNLK LFRP++M PD LIAEVILY
Sbjct: 121 MNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILY 161
>BC113424-1|AAI13425.1| 408|Homo sapiens FLJ37357 protein protein.
Length = 408
Score = 133 bits (322), Expect = 7e-30
Identities = 102/406 (25%), Positives = 178/406 (43%), Gaps = 17/406 (4%)
Query: 138 MSYTEKANKRKYCERLACFIKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLE 197
M+YTE+A+KR YC RL CFI+L DY+ ++ LT + L + L + TPS ++++
Sbjct: 1 MTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQ 60
Query: 198 GSALDEVLEVLPRQTDTCKWALFQVDAYVRPNGAVEL---------NPSQEIISSYLEKI 248
+E EV P + T + D + P EL PS E +
Sbjct: 61 KWITEEKPEV-PDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 119
Query: 249 TSYWDEHVRKFRQFLTEETLQMIVQPTIMGKQVEWSAGMSPNLYFLMNQDKKMLDDITFI 308
++ V + + P I K + G P+L + DK I+ I
Sbjct: 120 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 179
Query: 309 PTSIKNAYECVWLFLNRMQAFMDSFKEAHEMDVNIIK-QERDLNEFRKLCEKFVKQMEAI 367
+I+ A+E ++ + F FKE +D+ +K QE D+N F + EK+ KQ +
Sbjct: 180 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHK-- 237
Query: 368 EDVVSYQP---LGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGRECIDGILEGVENIS 424
D V+ +P +GL+ + +E P P R +V+ + P ++ +D I+ ++
Sbjct: 238 -DAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAE 296
Query: 425 GDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGEFNIPIPPEDMTQFL 484
+ P T +E V LD ++ R+ LM ++ +P PPED F
Sbjct: 297 YKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFA 356
Query: 485 GLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
+ ++ +R+ +D + R F +G D+ L +VN+++
Sbjct: 357 TMKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVK 402
>BC104884-1|AAI04885.1| 408|Homo sapiens FLJ37357 protein protein.
Length = 408
Score = 133 bits (322), Expect = 7e-30
Identities = 102/406 (25%), Positives = 178/406 (43%), Gaps = 17/406 (4%)
Query: 138 MSYTEKANKRKYCERLACFIKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLE 197
M+YTE+A+KR YC RL CFI+L DY+ ++ LT + L + L + TPS ++++
Sbjct: 1 MTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQ 60
Query: 198 GSALDEVLEVLPRQTDTCKWALFQVDAYVRPNGAVEL---------NPSQEIISSYLEKI 248
+E EV P + T + D + P EL PS E +
Sbjct: 61 KWITEEKPEV-PDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 119
Query: 249 TSYWDEHVRKFRQFLTEETLQMIVQPTIMGKQVEWSAGMSPNLYFLMNQDKKMLDDITFI 308
++ V + + P I K + G P+L + DK I+ I
Sbjct: 120 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 179
Query: 309 PTSIKNAYECVWLFLNRMQAFMDSFKEAHEMDVNIIK-QERDLNEFRKLCEKFVKQMEAI 367
+I+ A+E ++ + F FKE +D+ +K QE D+N F + EK+ KQ +
Sbjct: 180 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHK-- 237
Query: 368 EDVVSYQP---LGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGRECIDGILEGVENIS 424
D V+ +P +GL+ + +E P P R +V+ + P ++ +D I+ ++
Sbjct: 238 -DAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAE 296
Query: 425 GDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGEFNIPIPPEDMTQFL 484
+ P T +E V LD ++ R+ LM ++ +P PPED F
Sbjct: 297 YKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFA 356
Query: 485 GLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
+ ++ +R+ +D + R F +G D+ L +VN+++
Sbjct: 357 TMKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVK 402
>AK094676-1|BAC04400.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ37357 fis, clone BRAMY2023060. ).
Length = 408
Score = 133 bits (322), Expect = 7e-30
Identities = 102/406 (25%), Positives = 178/406 (43%), Gaps = 17/406 (4%)
Query: 138 MSYTEKANKRKYCERLACFIKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLE 197
M+YTE+A+KR YC RL CFI+L DY+ ++ LT + L + L + TPS ++++
Sbjct: 1 MTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQ 60
Query: 198 GSALDEVLEVLPRQTDTCKWALFQVDAYVRPNGAVEL---------NPSQEIISSYLEKI 248
+E EV P + T + D + P EL PS E +
Sbjct: 61 KWITEEKPEV-PDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 119
Query: 249 TSYWDEHVRKFRQFLTEETLQMIVQPTIMGKQVEWSAGMSPNLYFLMNQDKKMLDDITFI 308
++ V + + P I K + G P+L + DK I+ I
Sbjct: 120 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 179
Query: 309 PTSIKNAYECVWLFLNRMQAFMDSFKEAHEMDVNIIK-QERDLNEFRKLCEKFVKQMEAI 367
+I+ A+E ++ + F FKE +D+ +K QE D+N F + EK+ KQ +
Sbjct: 180 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHK-- 237
Query: 368 EDVVSYQP---LGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGRECIDGILEGVENIS 424
D V+ +P +GL+ + +E P P R +V+ + P ++ +D I+ ++
Sbjct: 238 -DAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAE 296
Query: 425 GDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGEFNIPIPPEDMTQFL 484
+ P T +E V LD ++ R+ LM ++ +P PPED F
Sbjct: 297 YKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFA 356
Query: 485 GLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
+ ++ +R+ +D + R F +G D+ L +VN+++
Sbjct: 357 TMKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVK 402
>AC096770-2|AAY24108.1| 408|Homo sapiens unknown protein.
Length = 408
Score = 133 bits (322), Expect = 7e-30
Identities = 102/406 (25%), Positives = 178/406 (43%), Gaps = 17/406 (4%)
Query: 138 MSYTEKANKRKYCERLACFIKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLE 197
M+YTE+A+KR YC RL CFI+L DY+ ++ LT + L + L + TPS ++++
Sbjct: 1 MTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQ 60
Query: 198 GSALDEVLEVLPRQTDTCKWALFQVDAYVRPNGAVEL---------NPSQEIISSYLEKI 248
+E EV P + T + D + P EL PS E +
Sbjct: 61 KWITEEKPEV-PDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 119
Query: 249 TSYWDEHVRKFRQFLTEETLQMIVQPTIMGKQVEWSAGMSPNLYFLMNQDKKMLDDITFI 308
++ V + + P I K + G P+L + DK I+ I
Sbjct: 120 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 179
Query: 309 PTSIKNAYECVWLFLNRMQAFMDSFKEAHEMDVNIIK-QERDLNEFRKLCEKFVKQMEAI 367
+I+ A+E ++ + F FKE +D+ +K QE D+N F + EK+ KQ +
Sbjct: 180 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHK-- 237
Query: 368 EDVVSYQP---LGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGRECIDGILEGVENIS 424
D V+ +P +GL+ + +E P P R +V+ + P ++ +D I+ ++
Sbjct: 238 -DAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAE 296
Query: 425 GDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGEFNIPIPPEDMTQFL 484
+ P T +E V LD ++ R+ LM ++ +P PPED F
Sbjct: 297 YKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFA 356
Query: 485 GLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
+ ++ +R+ +D + R F +G D+ L +VN+++
Sbjct: 357 TMKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVK 402
>Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 132 bits (319), Expect = 2e-29
Identities = 62/91 (68%), Positives = 74/91 (81%)
Query: 1215 KSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRN 1274
K+LAIQ VVFNCS+ LD+ MG+FF GLA++GAW CFDEFNRIDIEVLSV+AQQ+ TI+
Sbjct: 11 KALAIQTVVFNCSDLLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQK 70
Query: 1275 AKVAKQTRFMFEGREIKLVRTCAAFITMNPG 1305
A+ + RFMFEG EI LV + A FITMNPG
Sbjct: 71 AQQQRVERFMFEGVEIPLVPSYAVFITMNPG 101
>U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heavy
chain protein.
Length = 655
Score = 132 bits (319), Expect = 2e-29
Identities = 82/281 (29%), Positives = 132/281 (46%), Gaps = 2/281 (0%)
Query: 976 EDLTTDIVAMLSPEGERVNLGKGLKARGNVEDWLGKVEEAMFASVKRCMKFALKEYMVNE 1035
++ + I AM S EGE V + NVE WL + M ++++ +K + ++
Sbjct: 377 DEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQ 436
Query: 1036 RVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLLSYEKKCISDLNDLAALTR 1095
+ P+Q++ QI + + V +I+T L++ ++ ++++ +
Sbjct: 437 GAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQ-YTNIDTSSEDPG 495
Query: 1096 KDLTLLFRKVLCALITIDVHARDTISHMVEKHVQKANDFEWLKMIRYYWEEDIDNCVARM 1155
+ + L ALI +H D + + + V D+ W K +R+Y + D C +M
Sbjct: 496 NTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD-HTCCVQM 554
Query: 1156 SSAMYIYGHEYLGAGGVLVITPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAK 1215
+ + Y +EY G LV TPLTD+CYL L A+++ L L
Sbjct: 555 VDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGG 614
Query: 1216 SLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNR 1256
L Q +VFNC EG+D K MGR F GL GAW CFDEFNR
Sbjct: 615 LLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNR 655
Score = 108 bits (259), Expect = 3e-22
Identities = 74/293 (25%), Positives = 137/293 (46%), Gaps = 11/293 (3%)
Query: 652 KCKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILH----TRFTPDVVMNLQMFEELQA 707
K + +D K +P++ Y+R L P HW+ + +L T + +L +
Sbjct: 92 KLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIV 151
Query: 708 FQHSDELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDA--RDVYVLGGLDEIQA 765
+ +D L ++ +A E + L++++ F +I ++D+ R + ++ +I
Sbjct: 152 AKAAD-LKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVN 210
Query: 766 SLDESNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWYACQQTWMYLEVIFSAPD 825
+ ++ + ++ S + +V W + L + L+ Q+ W+YLE IF
Sbjct: 211 QVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG--- 267
Query: 826 IQRQLPNETRLFSIVDKSWKDIMRKLAKVPLAMPAATQPKLYEEFVRNNEMLDQIMKCLE 885
+ LP E F+ VD+ ++ IM + K T + + + L + + L
Sbjct: 268 -RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQRSLN 326
Query: 886 AYLETKRVAFPRFFFLSNDELLEILAQTRNPHAVQPHLRKCFDAIAKLEFGVK 938
+LE KR AFPRF+F+ +D+LLEIL Q+ NP +Q HL+K F I + F K
Sbjct: 327 EFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEK 379
>U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein.
Length = 80
Score = 128 bits (310), Expect = 2e-28
Identities = 59/80 (73%), Positives = 61/80 (76%)
Query: 1176 TPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMM 1235
TPLTDRCYLCLMGALQLDL DLAK+LAIQCVVFNCS+GLDYKMM
Sbjct: 1 TPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMM 60
Query: 1236 GRFFSGLATSGAWCCFDEFN 1255
GRFFSGLA SGAW CFDEFN
Sbjct: 61 GRFFSGLAQSGAWGCFDEFN 80
>U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy chain
isotype3 protein.
Length = 102
Score = 128 bits (308), Expect = 4e-28
Identities = 58/90 (64%), Positives = 71/90 (78%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAK+LA+QCVVFNCS+GLDY MG+FF GLA+SGAW CFDEFNRI++EVLSV+AQQ++
Sbjct: 13 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILC 72
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFIT 1301
I+ A K F+FEG E+KL C IT
Sbjct: 73 IQRAIQQKLVVFVFEGTELKLNPNCFVAIT 102
>U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy chain
isotype1 protein.
Length = 89
Score = 126 bits (304), Expect = 1e-27
Identities = 58/89 (65%), Positives = 71/89 (79%)
Query: 1213 LAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITI 1272
L K+LAIQ VVFNCS+ LD+ MG+FF GLA++GAW CFDEFNRIDIEVLSV++QQ+ TI
Sbjct: 1 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVSQQITTI 60
Query: 1273 RNAKVAKQTRFMFEGREIKLVRTCAAFIT 1301
+ A+ + RFMFEG EI LV +CA F T
Sbjct: 61 QKAQQQRVERFMFEGVEIPLVPSCAVFTT 89
>AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 123 bits (296), Expect = 1e-26
Identities = 57/93 (61%), Positives = 68/93 (73%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DLAK+L + CVV NC EG+DY+ +G+ FSGLA GAW CFDEFNRID VLSVI+ Q+ T
Sbjct: 9 DLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQT 68
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNP 1304
IRNA + + T F FEG+EI L FITMNP
Sbjct: 69 IRNALIHQLTTFQFEGQEISLDSRMGIFITMNP 101
>AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 83
Score = 115 bits (277), Expect = 2e-24
Identities = 52/78 (66%), Positives = 64/78 (82%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DL K+LAIQ VVFNCS+ LD+ MG+FF GLA++GAW CFDEFNRIDIEVLSV++QQ+ T
Sbjct: 6 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVSQQITT 65
Query: 1272 IRNAKVAKQTRFMFEGRE 1289
I+ A+ + RFMFEG E
Sbjct: 66 IQKAQQQRVERFMFEGVE 83
>AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein
protein.
Length = 617
Score = 109 bits (262), Expect = 1e-22
Identities = 111/453 (24%), Positives = 196/453 (43%), Gaps = 46/453 (10%)
Query: 1215 KSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRN 1274
++L Q V+ CS ++ + + + +G GAW ++ +++ +LS + Q+L + +
Sbjct: 1 QALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHH 60
Query: 1275 A-----KVAKQTRFMFEGREIKLVRTC---AAFITMNPGY-------AGRTELPDNLKAL 1319
+ A + + + +L+ + +++ GY A + +P NL L
Sbjct: 61 LYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVPANLHLL 120
Query: 1320 FRPISMMVPDYALIAEVILYSEGFESSKGLAKKMVQMYKLSSEQLS----------KQDH 1369
RP+++ +PD +AE+ L G + +A ++ + + L E +S KQ
Sbjct: 121 LRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQIL 180
Query: 1370 YDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAIL-FAGILSDLF 1428
D +R + K + EE LL AL S L L + G+L LF
Sbjct: 181 EDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHNLRGLLCALF 239
Query: 1429 PGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVI----QLHETMIVRWGVMLVGPTG 1484
P S + + ++K +++E Q+ + ++ QL + + G++L+GP G
Sbjct: 240 PSASQVLAE-PMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAG 298
Query: 1485 GGKTVVLHVLGDTYTRLYENGVEGSQ-YQPVRKYIMNPKSLTIGELYGEVNLQTLEWHDG 1543
GKT H L RL +Q QPV + P L+ E G L+ WH G
Sbjct: 299 SGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGW--LEGSCWHHG 356
Query: 1544 ILPLCLRTAVQCLNPDHQ-----------WLICDGPVDAVWIENMNTVLDDNKMLCLSNS 1592
I P LR A QC N + W+ICDG + W++++ +L + L L +
Sbjct: 357 IFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSG 416
Query: 1593 ERIKLTPYVHMVFEVADLAQASPATVSRCGMVY 1625
++I P ++ EVAD SP V C +V+
Sbjct: 417 QQIARPPGTFLLMEVADTTGISPTVVGCCALVW 449
>U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy chain
isotype2 protein.
Length = 83
Score = 108 bits (260), Expect = 2e-22
Identities = 51/83 (61%), Positives = 61/83 (73%)
Query: 1217 LAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAK 1276
L I +V NCSEGLDYK MGR +SGLA +GAW CFDEFNRI+IEVLSV+A Q++ I +A
Sbjct: 1 LGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSAL 60
Query: 1277 VAKQTRFMFEGREIKLVRTCAAF 1299
A T F F+G EI LV +C F
Sbjct: 61 AAGLTHFHFDGFEINLVWSCGIF 83
>Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 104 bits (250), Expect = 4e-21
Identities = 51/94 (54%), Positives = 62/94 (65%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DL + L VFNCSE +DYK G + GLA +GAW CFDEFNRI +EVL VIA Q+
Sbjct: 8 DLDRPLGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLYVIAVQVKC 67
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNPG 1305
+++A AK+ +F F G I LV T FITMNPG
Sbjct: 68 VQDAIRAKKKKFNFLGEIISLVPTVGIFITMNPG 101
>Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 104 bits (249), Expect = 5e-21
Identities = 48/94 (51%), Positives = 63/94 (67%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DL +++ I VFNCSE +DY+ G + GLA +GAW CFDEFNRI +EVLSV+A Q+ +
Sbjct: 8 DLGRAIGIMVYVFNCSEQMDYQSCGNIYKGLAQTGAWACFDEFNRITVEVLSVVAVQVKS 67
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNPG 1305
+++A K+ F F G I V T FITMNPG
Sbjct: 68 VQDAIRDKKDTFNFMGEIISCVPTVGIFITMNPG 101
>AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein.
Length = 207
Score = 103 bits (247), Expect = 9e-21
Identities = 44/91 (48%), Positives = 65/91 (71%)
Query: 1852 LNFSAQTSSPRTQEVIELRLDKRPRKAIGAPLGKKIIIFIDDVNMPKLDVYGAQPTIELL 1911
+NFS ++ +T+E+I +L +R + +GAP +I+IFIDD+NMP D+YGAQP +EL+
Sbjct: 109 INFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLELI 168
Query: 1912 RQFLDFGGVYDRDKLYWKDILDVVLSCSCAP 1942
RQ LD GGVYD +K WK+I D+ + +C P
Sbjct: 169 RQLLDLGGVYDTEKNTWKNIQDLSIVAACVP 199
>AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 103 bits (246), Expect = 1e-20
Identities = 50/93 (53%), Positives = 63/93 (67%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DL ++L I VFNCSE +DYK G + GLA +GAW CFDEFNRI +EVLSV+A Q+ +
Sbjct: 9 DLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKS 68
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNP 1304
I++A K+ F F G EI L + FITMNP
Sbjct: 69 IQDAIRDKKQWFSFLGEEISLNPSVGIFITMNP 101
>AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 101 bits (241), Expect = 5e-20
Identities = 47/93 (50%), Positives = 62/93 (66%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
DL ++L + VFNCSE +DYK +G + GL +GAW CFDEFNRI +EVLSV+A Q+
Sbjct: 9 DLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKM 68
Query: 1272 IRNAKVAKQTRFMFEGREIKLVRTCAAFITMNP 1304
I +A ++ RF+F G I L + FITMNP
Sbjct: 69 IHDAIRNRKKRFVFLGEAITLKPSVGIFITMNP 101
>Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy chain
protein.
Length = 107
Score = 96.3 bits (229), Expect = 1e-18
Identities = 45/95 (47%), Positives = 64/95 (67%), Gaps = 1/95 (1%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLIT 1271
D+ + L VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV AQQ+
Sbjct: 13 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYI 72
Query: 1272 IRNAKVAKQTRFMF-EGREIKLVRTCAAFITMNPG 1305
+ A+ ++ +F+F +G + L FITMNPG
Sbjct: 73 VLTARKERKKQFIFSDGDCVDLNPEFGVFITMNPG 107
>L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein.
Length = 141
Score = 93.1 bits (221), Expect = 1e-17
Identities = 53/141 (37%), Positives = 70/141 (49%), Gaps = 10/141 (7%)
Query: 1178 LTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMMGR 1237
LTDRCYL + AL+ L L L +VFNC E D++ MGR
Sbjct: 1 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 60
Query: 1238 FFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA----------KVAKQTRFMFEG 1287
F GL GAW CFDEFNR++ +LS ++QQ+ I+ A K +
Sbjct: 61 IFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLN 120
Query: 1288 REIKLVRTCAAFITMNPGYAG 1308
+++K+ A FITMNPGYAG
Sbjct: 121 KQVKVSPDMAIFITMNPGYAG 141
>AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 67
Score = 88.2 bits (209), Expect = 4e-16
Identities = 39/65 (60%), Positives = 49/65 (75%)
Query: 1228 EGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKVAKQTRFMFEG 1287
+GLDY +G+FF GL + GAW CFDEFNRID+EVLSV+AQQ++TI+ A MFEG
Sbjct: 1 DGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEG 60
Query: 1288 REIKL 1292
E+KL
Sbjct: 61 TELKL 65
>U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 84.6 bits (200), Expect = 5e-15
Identities = 35/44 (79%), Positives = 40/44 (90%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFN 1255
DLAK+LA+QCVVFNCS+GLDY MG+FF GLA+SGAW CFDEFN
Sbjct: 12 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWGCFDEFN 55
>U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein.
Length = 79
Score = 79.0 bits (186), Expect = 2e-13
Identities = 35/79 (44%), Positives = 45/79 (56%)
Query: 1176 TPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMM 1235
TPLTDRCY+ L AL + + D+ + L VVFNCS+ +D++ +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKDVVVFNCSDQMDFRGL 60
Query: 1236 GRFFSGLATSGAWCCFDEF 1254
GR F GLA SGAW CFDEF
Sbjct: 61 GRIFKGLAQSGAWGCFDEF 79
>AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens cDNA
FLJ44002 fis, clone TESTI4022873. ).
Length = 1205
Score = 78.6 bits (185), Expect = 3e-13
Identities = 70/387 (18%), Positives = 153/387 (39%), Gaps = 11/387 (2%)
Query: 352 EFRKLCEKFVKQMEAIEDVV-SYQPLGLIFLCLSPFQELFRPQPKRLFDVVLNVTPDIGR 410
E R++ +++ E ++ + S +G ++ ++ + K L VL++
Sbjct: 778 EVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLH 837
Query: 411 ECIDGILEGVENISGDITKDPETASELVAFNFMLDGLESRVAFXXXXXXXXXXXXDLMGE 470
+ +D I E +IS I + P + EL + G+ R+ +M E
Sbjct: 838 KEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDE 897
Query: 471 FNIPIPPEDMTQFLGLSVTLSTLRSDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLR 530
F + +D S S + ++ + + F D N + L+
Sbjct: 898 FLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQ 957
Query: 531 DEVTQPWLYDEKSDLEKVMETLDDLLEKLMACSARDKQIREWQKIFKIPPARLEQLDEAI 590
V ++ E S ++ + + ++L C ++IF +P ++L +
Sbjct: 958 LVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMV 1017
Query: 591 NDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSNTIV 650
+ + LW + +W +SW ++P + +D ++++ + + F + K + +
Sbjct: 1018 KEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV---EAFKTMHKCVKQFKDM 1074
Query: 651 PKCKEL-------IDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFE 703
P C+E+ I+ K +P+I LRNP ++ RHW + ++ P +
Sbjct: 1075 PACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCL 1134
Query: 704 ELQAFQHSDELMEVAGQASSEAGLESL 730
E+ H + + +VA A E +E +
Sbjct: 1135 EMNLQDHIESISKVAEVAGKEYAIEQV 1161
>AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 74.5 bits (175), Expect = 5e-12
Identities = 32/55 (58%), Positives = 41/55 (74%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
D+ + L VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRID+ VLSV A
Sbjct: 3 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAA 57
>U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 73.7 bits (173), Expect = 8e-12
Identities = 31/44 (70%), Positives = 37/44 (84%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFN 1255
DL K+LAIQ VVFNCS+ LD+ MG+FF GLA++GAW CFDEFN
Sbjct: 12 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWGCFDEFN 55
>AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 72.9 bits (171), Expect = 1e-11
Identities = 31/55 (56%), Positives = 41/55 (74%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFNRIDIEVLSVIA 1266
D+ + L VVFNCS+ +D++ +GR F GLA SG+W CFDEFNRI++ VLSV A
Sbjct: 3 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAA 57
>AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens cDNA
FLJ16607 fis, clone TESTI4010382, highly similar to
Rattus norvegicus dynein, cytoplasmic, heavy chain 2
(Dnch2). ).
Length = 1300
Score = 71.3 bits (167), Expect = 5e-11
Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 3/221 (1%)
Query: 2535 PPALVRFVMEPVCILMGV-KPDWDSTKKLLADVNFIGKLADYDKDHIPDATLKKIK--VY 2591
PP ++R ++E V LMG+ W S K LA +A +D +I + ++ ++
Sbjct: 2 PPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLF 61
Query: 2592 LTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLR 2651
F+P + S + WV+A Y+ V + P + + LK R
Sbjct: 62 KNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKR 121
Query: 2652 AKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEE 2711
++ + ++ +++++ ++ ++ E KL+A+V A + A L L E RW
Sbjct: 122 KLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNA 181
Query: 2712 SVKAATQQLHCTTGDIIVASGCIAYFGAFPSHYRRELELKW 2752
V T++L +A+ I Y A P R+ +W
Sbjct: 182 QVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEW 222
>U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy chain
isotype3b protein.
Length = 50
Score = 68.9 bits (161), Expect = 2e-10
Identities = 29/37 (78%), Positives = 33/37 (89%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAW 1248
DLAK+LA QCVVFNCS+GLDYK MG+FF GLA +GAW
Sbjct: 13 DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAW 49
>AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 134
Score = 66.9 bits (156), Expect = 1e-09
Identities = 31/77 (40%), Positives = 46/77 (59%)
Query: 1366 KQDHYDFGMRAVKSVLVMAGALKRANPDQHEEMTLLCALNDSNLPKFLAADAILFAGILS 1425
+Q HYDFG+R + SVL G+ KRA P+ E ++ L D NL K + D LF +++
Sbjct: 58 RQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLIN 117
Query: 1426 DLFPGVSLPARDYGVME 1442
DLFPG+ L + Y ++
Sbjct: 118 DLFPGLQLDSNTYAELQ 134
Score = 58.8 bits (136), Expect = 3e-07
Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Query: 1275 AKVAKQTRFMF-EGREIKLVRTCAAFITMNPGYAGRTELPDNLKALFRPISMMVPD 1329
A+ ++ +F+F +G + L F+TMNPGYAGR ELP+NLK FR ++MMVPD
Sbjct: 2 ARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPD 57
>U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 66.1 bits (154), Expect = 2e-09
Identities = 30/44 (68%), Positives = 33/44 (75%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFN 1255
DLAKSL CVVFNC E LDYK++ +FF GL SGA CFDEFN
Sbjct: 12 DLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGALGCFDEFN 55
>U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein.
Length = 77
Score = 64.1 bits (149), Expect = 7e-09
Identities = 32/77 (41%), Positives = 37/77 (48%)
Query: 1176 TPLTDRCYLCLMGALQLDLXXXXXXXXXXXXXXXXXDLAKSLAIQCVVFNCSEGLDYKMM 1235
TPLTDRCYL + AL+ L L L +VFNC E D++ M
Sbjct: 1 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 60
Query: 1236 GRFFSGLATSGAWCCFD 1252
GR F GL GAW CFD
Sbjct: 61 GRIFVGLCQVGAWGCFD 77
>U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein.
Length = 54
Score = 62.9 bits (146), Expect = 2e-08
Identities = 26/44 (59%), Positives = 31/44 (70%)
Query: 1212 DLAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAWCCFDEFN 1255
DL ++L I VFNCSE +DYK G + GLA +GAW CFDEFN
Sbjct: 11 DLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFN 54
>AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 1179
Score = 59.3 bits (137), Expect = 2e-07
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 2656 EVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTRWEESVKA 2715
++ + A L+ + + E++K Q + D + A +L LA E RW ESV+
Sbjct: 2 KIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVEN 61
Query: 2716 ATQQLHCTTGDIIVASGCIAYFGAFPSHYRREL-ELKWIAECSELEIP 2762
Q GD+++ S ++Y G F YR EL E WI L++P
Sbjct: 62 FRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVP 109
>AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein
protein.
Length = 94
Score = 58.4 bits (135), Expect = 3e-07
Identities = 26/79 (32%), Positives = 46/79 (58%)
Query: 1416 DAILFAGILSDLFPGVSLPARDYGVMEDVIKIIMLERKLQIEICQIRKVIQLHETMIVRW 1475
D F ++ D+FPG+ L +Y + +K + E +I QI+K ++L+E + R
Sbjct: 4 DCTRFDALIKDVFPGIKLKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRM 63
Query: 1476 GVMLVGPTGGGKTVVLHVL 1494
GV++VGP+G GK+ + +L
Sbjct: 64 GVVIVGPSGAGKSTLWRML 82
>U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy chain
isotype 11 protein.
Length = 37
Score = 45.2 bits (102), Expect = 0.003
Identities = 17/36 (47%), Positives = 24/36 (66%)
Query: 1213 LAKSLAIQCVVFNCSEGLDYKMMGRFFSGLATSGAW 1248
L ++L + VFNCSE +DYK +G + GL +GAW
Sbjct: 1 LGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAW 36
>AF311855-1|AAG42473.1| 2564|Homo sapiens spectrin beta IV protein.
Length = 2564
Score = 41.5 bits (93), Expect = 0.042
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 1314 CHELDGWIHEKMLMA---RDSTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 1368
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 1369 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1424
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1425 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1463
>AY004227-1|AAF93173.1| 2149|Homo sapiens betaIV spectrin isoform
sigma4 protein.
Length = 2149
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 1309 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 1363
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 1364 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1419
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1420 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1458
>AY004226-2|AAF93172.1| 1307|Homo sapiens betaIV spectrin isoform
sigma3 protein.
Length = 1307
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 57 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 111
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 112 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 167
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 168 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 206
>AF324064-1|AAQ14859.1| 2002|Homo sapiens beta spectrin IV protein.
Length = 2002
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 1314 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 1368
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 1369 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1424
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1425 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1463
>AF324063-1|AAQ14860.1| 2564|Homo sapiens non-erythrocytic
beta-spectrin 4 protein.
Length = 2564
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 1314 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 1368
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 1369 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1424
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1425 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1463
>AF082075-1|AAG38874.1| 2559|Homo sapiens beta4sigma1 spectrin
protein.
Length = 2559
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 1309 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 1363
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 1364 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1419
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1420 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1458
>AB046862-1|BAB13468.1| 1997|Homo sapiens KIAA1642 protein protein.
Length = 1997
Score = 41.1 bits (92), Expect = 0.055
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 653 CKELIDVIKEKLPVISYLRNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSD 712
C EL I EK+ + R+ + H + + H F ++ N + E+++ +
Sbjct: 929 CHELDGWIHEKMLMA---RDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQ 983
Query: 713 ELMEVAGQASSEAGLESLLKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDE 769
+LM+ + + A + L ++ + WA LE AR ++ D++ A LD+
Sbjct: 984 QLMQEKPELA--ASVRKKLGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDK 1039
Query: 770 SNIHISTILSSRNCGPIKSRVEEWAKNLELFAKTLEEWY 808
+H+ + L + G + V K L+ +EEWY
Sbjct: 1040 KLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWY 1078
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 40.3 bits (90), Expect = 0.096
Identities = 21/84 (25%), Positives = 44/84 (52%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+EA A + A + +K+++++EA++ ++ +EL + E R + + D A ++ +
Sbjct: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 2697 KLTQALADEKTRWEESVKAATQQL 2720
AL DEK R E + ++L
Sbjct: 1722 SGKSALLDEKRRLEARIAQLEEEL 1745
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/58 (31%), Positives = 33/58 (56%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE + QL ++ DEL+ ED +L+L+ ++ A+ R + +EK R
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 40.3 bits (90), Expect = 0.096
Identities = 21/84 (25%), Positives = 44/84 (52%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+EA A + A + +K+++++EA++ ++ +EL + E R + + D A ++ +
Sbjct: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 2697 KLTQALADEKTRWEESVKAATQQL 2720
AL DEK R E + ++L
Sbjct: 1722 SGKSALLDEKRRLEARIAQLEEEL 1745
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/58 (31%), Positives = 33/58 (56%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE + QL ++ DEL+ ED +L+L+ ++ A+ R + +EK R
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 40.3 bits (90), Expect = 0.096
Identities = 21/84 (25%), Positives = 44/84 (52%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+EA A + A + +K+++++EA++ ++ +EL + E R + + D A ++ +
Sbjct: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 2697 KLTQALADEKTRWEESVKAATQQL 2720
AL DEK R E + ++L
Sbjct: 1722 SGKSALLDEKRRLEARIAQLEEEL 1745
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/58 (31%), Positives = 33/58 (56%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE + QL ++ DEL+ ED +L+L+ ++ A+ R + +EK R
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 40.3 bits (90), Expect = 0.096
Identities = 21/84 (25%), Positives = 44/84 (52%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+EA A + A + +K+++++EA++ ++ +EL + E R + + D A ++ +
Sbjct: 157 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 216
Query: 2697 KLTQALADEKTRWEESVKAATQQL 2720
AL DEK R E + ++L
Sbjct: 217 SGKSALLDEKRRLEARIAQLEEEL 240
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/58 (31%), Positives = 33/58 (56%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE + QL ++ DEL+ ED +L+L+ ++ A+ R + +EK R
Sbjct: 30 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 87
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 40.3 bits (90), Expect = 0.096
Identities = 21/84 (25%), Positives = 44/84 (52%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+EA A + A + +K+++++EA++ ++ +EL + E R + + D A ++ +
Sbjct: 1704 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1763
Query: 2697 KLTQALADEKTRWEESVKAATQQL 2720
AL DEK R E + ++L
Sbjct: 1764 SGKSALLDEKRRLEARIAQLEEEL 1787
Score = 37.5 bits (83), Expect = 0.68
Identities = 18/58 (31%), Positives = 33/58 (56%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE + QL ++ DEL+ ED +L+L+ ++ A+ R + +EK R
Sbjct: 1577 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1634
>AF311856-1|AAG42474.1| 678|Homo sapiens spectrin beta IV protein.
Length = 678
Score = 38.7 bits (86), Expect = 0.29
Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 671 RNPALKPRHWVKIEEILHTRFTPDVVMNLQMFEELQAFQHSDELMEVAGQASSEAGLESL 730
R+ + H + + H F ++ N + E+++ + +LM+ + + A +
Sbjct: 5 RDSTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIE--REGQQLMQEKPELA--ASVRKK 60
Query: 731 LKKVEEIWAALEFPVILHKDARDVYVLGGLDEIQ---ASLDESNIHISTILSSRNCGPIK 787
L ++ + WA LE AR ++ D++ A LD+ +H+ + L + G
Sbjct: 61 LGEIRQCWAELESTT--QAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDL 118
Query: 788 SRVEEWAKNLELFAKTLEEWY 808
+ V K L+ +EEWY
Sbjct: 119 ATVNSQLKKLQSMESQVEEWY 139
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 37.1 bits (82), Expect = 0.90
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 66 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 122
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E+T +++ ++A QQL
Sbjct: 123 QAEQLSNELATERTTAQKN-ESARQQL 148
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 37.1 bits (82), Expect = 0.90
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 66 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 122
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E+T +++ ++A QQL
Sbjct: 123 QAEQLSNELATERTTAQKN-ESARQQL 148
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ DEL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 1744
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ DEL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 815 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 872
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 922 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 981
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 982 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 1031
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ DEL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 1744
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ DEL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 131 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 188
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 238 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 297
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 298 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 347
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 36.7 bits (81), Expect = 1.2
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ DEL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 1744
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 36.7 bits (81), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 2647 MAVLRAKQKEVEAIEAQLAKMMDELKT-VEDERLKLQADVDLAAARLSRAGKLTQALADE 2705
++ + +K + + + AQL K + EL+T ++D + KL+A+ A LTQ LAD
Sbjct: 1109 LSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL 1168
Query: 2706 KTRWEESVKAATQQLHCT 2723
R EE ++ QL T
Sbjct: 1169 NERLEEVGGSSLAQLEIT 1186
>Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein.
Length = 896
Score = 36.3 bits (80), Expect = 1.6
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 2635 KHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARL 2692
K E A ++ S+ A L +++ ++ E +LAK +EL ++ E +L+ V+ A+L
Sbjct: 418 KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 475
>U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor
receptor substrate protein.
Length = 896
Score = 36.3 bits (80), Expect = 1.6
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 2635 KHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARL 2692
K E A ++ S+ A L +++ ++ E +LAK +EL ++ E +L+ V+ A+L
Sbjct: 418 KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 475
>DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 36.3 bits (80), Expect = 1.6
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 2635 KHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARL 2692
K E A ++ S+ A L +++ ++ E +LAK +EL ++ E +L+ V+ A+L
Sbjct: 418 KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 475
>BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil domain
containing 1 protein.
Length = 1478
Score = 36.3 bits (80), Expect = 1.6
Identities = 20/69 (28%), Positives = 37/69 (53%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+E AA L A L Q EV+ ++AQ+ + +++ D++ K+Q+ + +A A L
Sbjct: 765 RELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHK 824
Query: 2697 KLTQALADE 2705
L Q L ++
Sbjct: 825 TLVQQLKEQ 833
>BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil domain
containing 1 protein.
Length = 1478
Score = 36.3 bits (80), Expect = 1.6
Identities = 20/69 (28%), Positives = 37/69 (53%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+E AA L A L Q EV+ ++AQ+ + +++ D++ K+Q+ + +A A L
Sbjct: 765 RELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHK 824
Query: 2697 KLTQALADE 2705
L Q L ++
Sbjct: 825 TLVQQLKEQ 833
>BC071599-1|AAH71599.1| 1121|Homo sapiens pleckstrin homology domain
containing, family A member 7 protein.
Length = 1121
Score = 36.3 bits (80), Expect = 1.6
Identities = 27/134 (20%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Query: 2557 DSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWV 2616
D+ +L D+ ++ L +D + D +LK +K+ + D + +V + + +
Sbjct: 654 DTYLQLKKDLEYLD-LKMTGRDLLKDRSLKPVKIAESDTDVKLSIFCEQDRVLQDLEDKI 712
Query: 2617 QAI----DMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELK 2672
+A+ D V V+ ++ ++++ L+ + + Q+++ I A+L++ E++
Sbjct: 713 RALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEME 772
Query: 2673 TVEDERLKLQADVD 2686
+E LKL+ DV+
Sbjct: 773 NAWNEYLKLENDVE 786
>BC033239-1|AAH33239.1| 748|Homo sapiens PLEKHA7 protein protein.
Length = 748
Score = 36.3 bits (80), Expect = 1.6
Identities = 27/134 (20%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Query: 2557 DSTKKLLADVNFIGKLADYDKDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWV 2616
D+ +L D+ ++ L +D + D +LK +K+ + D + +V + + +
Sbjct: 280 DTYLQLKKDLEYLD-LKMTGRDLLKDRSLKPVKIAESDTDVKLSIFCEQDRVLQDLEDKI 338
Query: 2617 QAI----DMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELK 2672
+A+ D V V+ ++ ++++ L+ + + Q+++ I A+L++ E++
Sbjct: 339 RALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEME 398
Query: 2673 TVEDERLKLQADVD 2686
+E LKL+ DV+
Sbjct: 399 NAWNEYLKLENDVE 412
>AL833308-1|CAD89924.1| 878|Homo sapiens hypothetical protein
protein.
Length = 878
Score = 36.3 bits (80), Expect = 1.6
Identities = 20/69 (28%), Positives = 37/69 (53%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+E AA L A L Q EV+ ++AQ+ + +++ D++ K+Q+ + +A A L
Sbjct: 165 RELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHK 224
Query: 2697 KLTQALADE 2705
L Q L ++
Sbjct: 225 TLVQQLKEQ 233
>AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 36.3 bits (80), Expect = 1.6
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 2635 KHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARL 2692
K E A ++ S+ A L +++ ++ E +LAK +EL ++ E +L+ V+ A+L
Sbjct: 418 KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 475
>AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil domain
containing 1 protein.
Length = 1478
Score = 36.3 bits (80), Expect = 1.6
Identities = 20/69 (28%), Positives = 37/69 (53%)
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+E AA L A L Q EV+ ++AQ+ + +++ D++ K+Q+ + +A A L
Sbjct: 765 RELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHK 824
Query: 2697 KLTQALADE 2705
L Q L ++
Sbjct: 825 TLVQQLKEQ 833
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 35.9 bits (79), Expect = 2.1
Identities = 44/176 (25%), Positives = 87/176 (49%), Gaps = 17/176 (9%)
Query: 495 SDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLRDEVTQPWLYDEKSDLEKVMETLDD 554
S +D +I+++++L + +++ K L N L + Q L D++ +L K+ LD
Sbjct: 638 SQLDIQIKAKTEL--LLSAEAAKTAQRADLQ-NHL--DTAQNALQDKQQELNKITTQLDQ 692
Query: 555 LLEKLMA----CSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMF 610
+ KL CS + ++E+++ + + E+L+ I ++ L KASKE +
Sbjct: 693 VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKE-QALQ 751
Query: 611 KSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSNT--IVPKCKELIDVIKEKL 664
NT D+ E++ T +S +++K + S+T + K E ++ IK+KL
Sbjct: 752 DLQQQRQLNT-DL-ELRATELSKQL---EMEKEIVSSTRLDLQKKSEALESIKQKL 802
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 35.9 bits (79), Expect = 2.1
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 2635 KHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLA---AAR 2691
K +EA L+ V+ + K ++++ +EA L K + + +E ER L A + A
Sbjct: 503 KLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAV 562
Query: 2692 LSRAGKLTQALADEKTRWEESVK 2714
L++ + L DE T+ E+VK
Sbjct: 563 LNQLQEKNHTLQDEVTQLTENVK 585
Score = 35.1 bits (77), Expect = 3.6
Identities = 44/176 (25%), Positives = 86/176 (48%), Gaps = 17/176 (9%)
Query: 495 SDVDARIESRSKLAGMFASQIGKDIMNLMLDVNKLRDEVTQPWLYDEKSDLEKVMETLDD 554
S +D +I+++++L + +++ K L N L + Q L D+ +L K+ LD
Sbjct: 638 SQLDIQIKAKTEL--LLSAEAAKTAQRADLQ-NHL--DTAQNALQDKHQELNKITTQLDQ 692
Query: 555 LLEKLMA----CSARDKQIREWQKIFKIPPARLEQLDEAINDVKLRQLLWKASKEWNDMF 610
+ KL CS + ++E+++ + + E+L+ I ++ L KASKE +
Sbjct: 693 VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKE-QALQ 751
Query: 611 KSWYDNPFNTLDVDEIQNTTISYGKIFNQLDKGLPSNT--IVPKCKELIDVIKEKL 664
NT D+ E++ T +S +++K + S+T + K E ++ IK+KL
Sbjct: 752 DLQQQRQLNT-DL-ELRATELSKQL---EMEKEIVSSTRLDLQKKSEALESIKQKL 802
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 822 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 878
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 879 QAEQLSNELATERSTAQKN-ESARQQL 904
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1708 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1764
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1765 QAEQLSNELATERSTAQKN-ESARQQL 1790
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1708 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1764
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1765 QAEQLSNELATERSTAQKN-ESARQQL 1790
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 234 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 290
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 291 QAEQLSNELATERSTAQKN-ESARQQL 316
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 61 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 118
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1715 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1771
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1772 QAEQLSNELATERSTAQKN-ESARQQL 1797
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1715 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1771
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1772 QAEQLSNELATERSTAQKN-ESARQQL 1797
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 358 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 414
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 415 QAEQLSNELATERSTAQKN-ESARQQL 440
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 185 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 242
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 358 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 414
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 415 QAEQLSNELATERSTAQKN-ESARQQL 440
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 185 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 242
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1593 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1649
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1650 QAEQLSNELATERSTAQKN-ESARQQL 1675
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1420 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1477
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 1720 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 1776
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ ++A QQL
Sbjct: 1777 QAEQLSNELATERSTAQKN-ESARQQL 1802
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 1547 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1604
>BC111765-1|AAI11766.1| 597|Homo sapiens chromosome 11 open reading
frame 47 protein.
Length = 597
Score = 35.1 bits (77), Expect = 3.6
Identities = 16/62 (25%), Positives = 32/62 (51%)
Query: 3 IKFFKVYRYWKAFYVWRKSILFRKFSKIRTKLAKNLFILTPVLGRALLNVQAMCCEMYMK 62
I FFK K+F W+K++ + +++ L +L + P G LL++ + E++
Sbjct: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
Query: 63 SF 64
S+
Sbjct: 421 SW 422
>AK093028-1|BAC04023.1| 286|Homo sapiens protein ( Homo sapiens
cDNA FLJ35709 fis, clone SPLEN2020512. ).
Length = 286
Score = 35.1 bits (77), Expect = 3.6
Identities = 16/62 (25%), Positives = 32/62 (51%)
Query: 3 IKFFKVYRYWKAFYVWRKSILFRKFSKIRTKLAKNLFILTPVLGRALLNVQAMCCEMYMK 62
I FFK K+F W+K++ + +++ L +L + P G LL++ + E++
Sbjct: 50 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 109
Query: 63 SF 64
S+
Sbjct: 110 SW 111
>BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine nucleotide
exchange factor protein.
Length = 710
Score = 34.7 bits (76), Expect = 4.8
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 975 PEDLTTDIVAMLSPEGERVNLGKGL---KARGNVEDWLG---KVEEAMF------ASVKR 1022
PE T + +LS R NL + L ++ G +E K++EAMF AS +
Sbjct: 231 PERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYK 290
Query: 1023 CMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLL 1077
+ + +M NER+ + +HP++ + S ++ V E F LE+ R++ ++
Sbjct: 291 SLNLLVSHFMENERIRKI-LHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIV 344
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 34.7 bits (76), Expect = 4.8
Identities = 25/111 (22%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2617 QAIDMYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVED 2676
+AI K+ ++ + + + A + ++A + +K+++++EA++ ++ +EL E
Sbjct: 1057 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1116
Query: 2677 ERLKLQADVD-LAAARLSRAGKLTQALADEKTRWEESVKAATQQLHCTTGD 2726
+ + Q + D LA + +GK AL +EK R E + ++L G+
Sbjct: 1117 AKRQAQQERDELADEIANSSGKGALAL-EEKRRLEARIAQLEEELEEEQGN 1166
Score = 33.9 bits (74), Expect = 8.4
Identities = 16/58 (27%), Positives = 34/58 (58%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA +++VE ++ QL ++ EL+ ED +L+L+ ++ A+ R + ++EK +
Sbjct: 950 RALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1007
>AJ238899-1|CAC00686.1| 425|Homo sapiens guanine nucleotide exchange
factor protein.
Length = 425
Score = 34.7 bits (76), Expect = 4.8
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 975 PEDLTTDIVAMLSPEGERVNLGKGL---KARGNVEDWLG---KVEEAMF------ASVKR 1022
PE T + +LS R NL + L ++ G +E K++EAMF AS +
Sbjct: 73 PERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYK 132
Query: 1023 CMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLL 1077
+ + +M NER+ + +HP++ + S ++ V E F LE+ R++ ++
Sbjct: 133 SLNLLVSHFMENERIRKI-LHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIV 186
>AC016692-1|AAX93288.1| 582|Homo sapiens unknown protein.
Length = 582
Score = 34.7 bits (76), Expect = 4.8
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 975 PEDLTTDIVAMLSPEGERVNLGKGL---KARGNVEDWLG---KVEEAMF------ASVKR 1022
PE T + +LS R NL + L ++ G +E K++EAMF AS +
Sbjct: 103 PERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYK 162
Query: 1023 CMKFALKEYMVNERVDWVEMHPNQVVLTVSQIMWAKGVHEVFNLEIPLRIDTGLL 1077
+ + +M NER+ + +HP++ + S ++ V E F LE+ R++ ++
Sbjct: 163 SLNLLVSHFMENERIRKI-LHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIV 216
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 34.3 bits (75), Expect = 6.3
Identities = 38/146 (26%), Positives = 68/146 (46%), Gaps = 8/146 (5%)
Query: 2582 DATLKKIKVYLTHKDFNPDTVVKV--SKVCRSMVLWVQAIDMYAKVFRVVEPKILKHKEA 2639
+A +K++ L + +V K SM + ID +V + +E + + K
Sbjct: 1171 EAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME 1230
Query: 2640 AAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARL-SRAGKL 2698
L S + + +E + L + ELKT E+E+ +L D+ ARL + AG+
Sbjct: 1231 TDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEY 1290
Query: 2699 TQALADEK----TRWEESVKAATQQL 2720
++ L DEK ++ S +A+TQQ+
Sbjct: 1291 SRQL-DEKDALVSQLSRSKQASTQQI 1315
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 34.3 bits (75), Expect = 6.3
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Query: 2577 KDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKH 2636
+DHI T++ + K++N ++ ++ + + + + + + E KIL
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+ +K A L K+KE+E + + +ELK +ED RL+ ++ LA +
Sbjct: 1591 ENQVYSMK---AELETKKKELEHVNLSVKSKEEELKALED-RLESESAAKLAELKRKAEQ 1646
Query: 2697 KLT---QALADEKTRWEESVKAATQ 2718
K+ + L + EE K T+
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTE 1671
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 34.3 bits (75), Expect = 6.3
Identities = 16/58 (27%), Positives = 32/58 (55%)
Query: 2651 RAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAGKLTQALADEKTR 2708
RA + ++E ++ QL ++ DEL+ ED +L+L+ ++ + R + +EK R
Sbjct: 444 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 501
Score = 34.3 bits (75), Expect = 6.3
Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 2634 LKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLS 2693
L+ +E A L S ++ A Q E +EA++A++ +EL E+E+ ++A D
Sbjct: 617 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL---EEEQGNMEAMSDRVRKATQ 673
Query: 2694 RAGKLTQALADEKTRWEESVKAATQQL 2720
+A +L+ LA E++ +++ +++ QQL
Sbjct: 674 QAEQLSNELATERSTAQKN-ESSRQQL 699
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 34.3 bits (75), Expect = 6.3
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Query: 2577 KDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKH 2636
+DHI T++ + K++N ++ ++ + + + + + + E KIL
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+ +K A L K+KE+E + + +ELK +ED RL+ ++ LA +
Sbjct: 1591 ENQVYSMK---AELETKKKELEHVNLSVKSKEEELKALED-RLESESAAKLAELKRKAEQ 1646
Query: 2697 KLT---QALADEKTRWEESVKAATQ 2718
K+ + L + EE K T+
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTE 1671
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 34.3 bits (75), Expect = 6.3
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Query: 2577 KDHIPDATLKKIKVYLTHKDFNPDTVVKVSKVCRSMVLWVQAIDMYAKVFRVVEPKILKH 2636
+DHI T++ + K++N ++ ++ + + + + + + E KIL
Sbjct: 1386 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1445
Query: 2637 KEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLKLQADVDLAAARLSRAG 2696
+ +K A L K+KE+E + + +ELK +ED RL+ ++ LA +
Sbjct: 1446 ENQVYSMK---AELETKKKELEHVNLSVKSKEEELKALED-RLESESAAKLAELKRKAEQ 1501
Query: 2697 KLT---QALADEKTRWEESVKAATQ 2718
K+ + L + EE K T+
Sbjct: 1502 KIAAIKKQLLSQMEEKEEQYKKGTE 1526
>AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.
Length = 1322
Score = 34.3 bits (75), Expect = 6.3
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 15/72 (20%)
Query: 2291 DGVYYFFINRVRGKLHLCICMSPVGEAFRRRCRMFPSLVNCCTID-WFTKWPPEALLSVA 2349
DG Y+ R++ LCIC + RRCR+ P C +D ++ W P A
Sbjct: 881 DGARYWPGQRIKADCQLCICQ----DGRPRRCRLNPD----CAVDCGWSSWSPWA----- 927
Query: 2350 HQCLQPLGNQEI 2361
+CL P G+Q I
Sbjct: 928 -KCLGPCGSQSI 938
>X06882-1|CAA29999.1| 375|Homo sapiens cd14 protein precursor
protein.
Length = 375
Score = 33.9 bits (74), Expect = 8.4
Identities = 13/59 (22%), Positives = 26/59 (44%)
Query: 578 IPPARLEQLDEAINDVKLRQLLWKASKEWNDMFKSWYDNPFNTLDVDEIQNTTISYGKI 636
+PP LE A++ ++LR + W + W + W L + + + SY ++
Sbjct: 132 MPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSYEQV 190
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 33.9 bits (74), Expect = 8.4
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 157 IKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLEGSALDEVLEVLPRQTDTCK 216
+KL+D + L L SNY+ NF P L+ + DE +++ +T C
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFC------CNFNPPSNLIISGSFDETVKIWEVKTGKC- 159
Query: 217 WALFQVDAYVRPNGAVELNPSQE-IISSYLEKITSYWD 253
L + A+ P AV N S I+S + + WD
Sbjct: 160 --LKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
>BC119717-1|AAI19718.1| 438|Homo sapiens C1orf67 protein protein.
Length = 438
Score = 33.9 bits (74), Expect = 8.4
Identities = 18/66 (27%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 2 QIKFFKVYRYWKAFYVWRKSILFRKFSKIRTKLAKNLFILTPVLGRALLNVQAMCCE-MY 60
Q K F +R KAF W+ ++ K K R+ L +LF+ + L+ ++ +C + +
Sbjct: 233 QFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIRGLCEDAIN 292
Query: 61 MKSFAD 66
+K++ D
Sbjct: 293 LKNYND 298
>BC119716-1|AAI19717.1| 438|Homo sapiens C1orf67 protein protein.
Length = 438
Score = 33.9 bits (74), Expect = 8.4
Identities = 18/66 (27%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 2 QIKFFKVYRYWKAFYVWRKSILFRKFSKIRTKLAKNLFILTPVLGRALLNVQAMCCE-MY 60
Q K F +R KAF W+ ++ K K R+ L +LF+ + L+ ++ +C + +
Sbjct: 233 QFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIRGLCEDAIN 292
Query: 61 MKSFAD 66
+K++ D
Sbjct: 293 LKNYND 298
>BC070236-1|AAH70236.1| 116|Homo sapiens NADH dehydrogenase
(ubiquinone) 1 alpha subcomplex, 5, 13kDa protein.
Length = 116
Score = 33.9 bits (74), Expect = 8.4
Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Query: 2621 MYAKVFRVVEPKILKHKEAAAILKSVMAVLRAKQKEVEAIEAQLAKMMDELKTVEDERLK 2680
+Y K+ V+E +I K+ AA K ++ K V+A E + K+ D+L+ + E +
Sbjct: 27 LYTKILDVLE-EIPKN---AAYRKYTEQIINEKLAMVKA-EPDVKKLEDQLQGGQLEEVI 81
Query: 2681 LQADVDLAAARLSRAGKLTQALADE 2705
LQA+ +L AR R KL + L +E
Sbjct: 82 LQAEHELNLARKMREWKLWEPLVEE 106
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 33.9 bits (74), Expect = 8.4
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 157 IKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLEGSALDEVLEVLPRQTDTCK 216
+KL+D + L L SNY+ NF P L+ + DE +++ +T C
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFC------CNFNPPSNLIISGSFDETVKIWEVKTGKC- 159
Query: 217 WALFQVDAYVRPNGAVELNPSQE-IISSYLEKITSYWD 253
L + A+ P AV N S I+S + + WD
Sbjct: 160 --LKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
>AL590547-1|CAH73045.1| 430|Homo sapiens chromosome 1 open reading
frame 67 protein.
Length = 430
Score = 33.9 bits (74), Expect = 8.4
Identities = 18/66 (27%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 2 QIKFFKVYRYWKAFYVWRKSILFRKFSKIRTKLAKNLFILTPVLGRALLNVQAMCCE-MY 60
Q K F +R KAF W+ ++ K K R+ L +LF+ + L+ ++ +C + +
Sbjct: 225 QFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIRGLCEDAIN 284
Query: 61 MKSFAD 66
+K++ D
Sbjct: 285 LKNYND 290
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 33.9 bits (74), Expect = 8.4
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 157 IKLFDYMTNYMLYRLTKRSNYMLADMLRIHVNFTPSRELLEGSALDEVLEVLPRQTDTCK 216
+KL+D + L L SNY+ NF P L+ + DE +++ +T C
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFC------CNFNPPSNLIISGSFDETVKIWEVKTGKC- 159
Query: 217 WALFQVDAYVRPNGAVELNPSQE-IISSYLEKITSYWD 253
L + A+ P AV N S I+S + + WD
Sbjct: 160 --LKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.138 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 379,134,165
Number of Sequences: 224733
Number of extensions: 15345859
Number of successful extensions: 38126
Number of sequences better than 10.0: 159
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 36877
Number of HSP's gapped (non-prelim): 683
length of query: 2768
length of database: 73,234,838
effective HSP length: 103
effective length of query: 2665
effective length of database: 50,087,339
effective search space: 133482758435
effective search space used: 133482758435
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 74 (33.9 bits)
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