Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000689-TA|BGIBMGA000689-PA|IPR001382|Glycoside
hydrolase, family 47, IPR003137|Protease-associated PA
(822 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL096819-3|CAI21741.1| 932|Homo sapiens ER degradation enhancer... 737 0.0
AF288393-1|AAG60613.1| 889|Homo sapiens C1orf22 protein. 737 0.0
D86967-1|BAA13203.2| 666|Homo sapiens KIAA0212 protein. 359 2e-98
BC019088-1|AAH19088.1| 657|Homo sapiens ER degradation enhancer... 359 2e-98
CR457266-1|CAG33547.1| 578|Homo sapiens C20orf31 protein. 316 2e-85
BC016184-1|AAH16184.1| 578|Homo sapiens ER degradation enhancer... 316 2e-85
BC001371-1|AAH01371.1| 578|Homo sapiens ER degradation enhancer... 316 2e-85
AL356652-1|CAH73763.1| 578|Homo sapiens ER degradation enhancer... 316 2e-85
AL135844-1|CAI19292.1| 578|Homo sapiens ER degradation enhancer... 316 2e-85
AK023931-1|BAB14731.1| 578|Homo sapiens protein ( Homo sapiens ... 316 2e-85
AK001645-1|BAA91806.1| 578|Homo sapiens protein ( Homo sapiens ... 316 2e-85
BC105586-1|AAI05587.1| 242|Homo sapiens EDEM3 protein protein. 287 1e-76
AY358580-1|AAQ88943.1| 541|Homo sapiens C20orf31 protein. 283 2e-75
BC006079-1|AAH06079.1| 699|Homo sapiens mannosidase, alpha, cla... 164 1e-39
BC002953-1|AAH02953.1| 699|Homo sapiens mannosidase, alpha, cla... 164 1e-39
AY358465-1|AAQ88830.1| 699|Homo sapiens MAN1B1 protein. 164 1e-39
AL929554-19|CAH72887.1| 699|Homo sapiens mannosidase, alpha, cl... 164 1e-39
AL807752-35|CAI12781.1| 699|Homo sapiens mannosidase, alpha, cl... 164 1e-39
AF148509-1|AAF03215.1| 699|Homo sapiens alpha 1,2-mannosidase p... 164 1e-39
AF145732-1|AAD45504.1| 663|Homo sapiens endoplasmic reticulum a... 164 1e-39
X74837-1|CAA52831.1| 625|Homo sapiens Man9-mannosidase protein. 149 3e-35
AL078600-1|CAB75695.2| 653|Homo sapiens mannosidase, alpha, cla... 147 1e-34
AL022722-2|CAI20315.1| 653|Homo sapiens mannosidase, alpha, cla... 147 1e-34
BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, cla... 146 2e-34
AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, cla... 146 2e-34
AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, cla... 146 2e-34
AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase I... 146 2e-34
AL031280-2|CAI19714.1| 630|Homo sapiens mannosidase, alpha, cla... 138 1e-31
AL031280-1|CAI19713.1| 450|Homo sapiens mannosidase, alpha, cla... 138 1e-31
AF261655-1|AAF97058.1| 630|Homo sapiens 1,2-alpha-mannosidase I... 138 1e-31
AB209275-1|BAD92512.1| 482|Homo sapiens mannosidase, alpha, cla... 108 7e-23
AL358072-2|CAH71080.1| 343|Homo sapiens mannosidase, alpha, cla... 103 3e-21
AL157902-4|CAI22318.1| 343|Homo sapiens mannosidase, alpha, cla... 103 3e-21
AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens ... 90 3e-17
AK074559-1|BAC11060.1| 178|Homo sapiens .2.1.113). protein. 85 1e-15
AF053626-1|AAC26201.1| 251|Homo sapiens alpha 1,2-mannosidase I... 84 2e-15
AB209276-1|BAD92513.1| 185|Homo sapiens alpha 1,2-mannosidase v... 84 2e-15
AL157902-2|CAI22316.1| 203|Homo sapiens mannosidase, alpha, cla... 79 8e-14
AL096819-2|CAI21740.1| 155|Homo sapiens ER degradation enhancer... 76 4e-13
AK023095-1|BAB14402.1| 155|Homo sapiens protein ( Homo sapiens ... 76 4e-13
AF053621-1|AAC26200.1| 358|Homo sapiens alpha 1,2-mannosidase I... 64 1e-09
AL929554-1|CAH72871.2| 329|Homo sapiens mannosidase, alpha, cla... 60 3e-08
BC065827-1|AAH65827.1| 367|Homo sapiens MAN1A1 protein protein. 56 5e-07
AL157902-3|CAI22317.1| 97|Homo sapiens mannosidase, alpha, cla... 55 9e-07
BC005069-1|AAH05069.1| 188|Homo sapiens chromosome 2 open readi... 47 2e-04
AY358605-1|AAQ88968.1| 188|Homo sapiens C2orf7 protein. 47 2e-04
AC010913-2|AAX88901.1| 188|Homo sapiens unknown protein. 47 2e-04
CR457340-1|CAG33621.1| 350|Homo sapiens DKFZP566H073 protein. 40 0.027
BC010139-1|AAH10139.1| 350|Homo sapiens ring finger protein 167... 40 0.027
AL834284-1|CAD38958.1| 349|Homo sapiens hypothetical protein pr... 40 0.027
AL050060-1|CAB43253.1| 324|Homo sapiens hypothetical protein pr... 40 0.027
AK025329-1|BAB15113.1| 350|Homo sapiens protein ( Homo sapiens ... 40 0.027
AC005764-1|AAC62428.1| 420|Homo sapiens R31343_1 protein. 40 0.027
BC101992-1|AAI01993.1| 314|Homo sapiens RNF150 protein protein. 39 0.083
BC017592-1|AAH17592.2| 429|Homo sapiens zinc and ring finger 4 ... 39 0.083
AB033040-1|BAA86528.1| 462|Homo sapiens KIAA1214 protein protein. 39 0.083
CR456804-1|CAG33085.1| 381|Homo sapiens RNF13 protein. 37 0.33
BC017878-1|AAH17878.1| 291|Homo sapiens RNF13 protein protein. 37 0.33
BC009803-1|AAH09803.1| 381|Homo sapiens ring finger protein 13 ... 37 0.33
BC009781-1|AAH09781.1| 381|Homo sapiens ring finger protein 13 ... 37 0.33
AF070558-1|AAC28641.1| 381|Homo sapiens RING zinc finger protei... 37 0.33
AF037204-1|AAC03769.1| 381|Homo sapiens RING zinc finger protei... 37 0.33
BC019353-1|AAH19353.1| 254|Homo sapiens Unknown (protein for IM... 33 3.1
AL606833-2|CAI41229.1| 249|Homo sapiens ring finger protein 128... 33 5.4
AL606833-1|CAI41228.1| 402|Homo sapiens ring finger protein 128... 33 5.4
AL391315-3|CAI39547.1| 249|Homo sapiens ring finger protein 128... 33 5.4
AL391315-2|CAI39546.1| 402|Homo sapiens ring finger protein 128... 33 5.4
AK126553-1|BAC86589.1| 402|Homo sapiens protein ( Homo sapiens ... 33 5.4
AK127005-1|BAC86786.1| 223|Homo sapiens protein ( Homo sapiens ... 32 7.2
AK027295-1|BAB55021.1| 350|Homo sapiens protein ( Homo sapiens ... 32 7.2
BC131536-1|AAI31537.1| 1631|Homo sapiens IQ motif containing GTP... 32 9.5
BC022038-1|AAH22038.1| 376|Homo sapiens ring finger protein 133... 32 9.5
AY253300-1|AAP06954.1| 1631|Homo sapiens IQGAP3 protein. 32 9.5
AL365181-1|CAI13046.1| 1631|Homo sapiens IQ motif containing GTP... 32 9.5
AK098524-1|BAC05321.1| 376|Homo sapiens protein ( Homo sapiens ... 32 9.5
AF447589-1|AAM22872.1| 376|Homo sapiens unknown protein. 32 9.5
AC006463-1|AAQ96858.1| 376|Homo sapiens unknown protein. 32 9.5
AB105103-1|BAC78211.1| 1631|Homo sapiens IQGAP3 protein. 32 9.5
>AL096819-3|CAI21741.1| 932|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 3 protein.
Length = 932
Score = 737 bits (1822), Expect = 0.0
Identities = 365/734 (49%), Positives = 499/734 (67%), Gaps = 38/734 (5%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MF HAY YME+AYPADELMPL+C+GR +G PSRGD+DDALG F +
Sbjct: 59 MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLN 118
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF A++ V++DV+ D D+VVSVFETNIR+LGGLL H LA LK +QWYN+E
Sbjct: 119 KTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDE 178
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESR-----ETCTACAGTMILEMA 175
LL MA+ LG ++LPAFNT++G+P+ +INL+ GIR E+R +TCTACAGT+ILE A
Sbjct: 179 LLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRK-PEARTGTETDTCTACAGTLILEFA 237
Query: 176 ALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYE 235
AL+R TG I+E+ A K++D LW+ R R+S+L+G INIH+GDWVRKDSGVGAGIDSYYE
Sbjct: 238 ALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYE 297
Query: 236 YCLKAYILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPG 295
Y LKAY+LLGD+ +L RF HY+AIM+YIS+ P++L VH+H+P L +R +MDALLAF+PG
Sbjct: 298 YLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWMDALLAFFPG 357
Query: 296 LQVLLGDVRPAVETHEMLYQVMQRHTFIPEAFTSDFQVHWGQHPLRPEFLESTYFLHRAT 355
LQVL GD+RPA+ETHEMLYQV+++H F+PEAFT+DF+VHW QHPLRPEF ESTYFL++AT
Sbjct: 358 LQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRVHWAQHPLRPEFAESTYFLYKAT 417
Query: 356 EDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLFGDE 415
D +YL+VGKT+++ L ++ RVPCG+A++ DVRT +HEDRMDSF LAE FKYLY+LF D+
Sbjct: 418 GDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYLLFADK 477
Query: 416 KDFPIKLEDYVLTTEAHFLPLSLATVGKNTS--YFTLKIDDPDEDKYRKTCPNTASLVP- 472
+D +EDY+ TTEAH LPL L+T ++ S T + + D+ + TCPNT L P
Sbjct: 478 EDIIFDIEDYIFTTEAHLLPLWLSTTNQSISKKNTTSEYTELDDSNFDWTCPNTQILFPN 537
Query: 473 -----EKVRQPMRQLLGS--------------TAARPPARLRPL--NDPRQINALSDMGI 511
+ +R+P++ ++ + A+PP R R +P + L MG+
Sbjct: 538 DPLYAQSIREPLKNVVDKSCPRGIIRVEESFRSGAKPPLRARDFMATNPEHLEILKKMGV 597
Query: 512 SVLTLPDGRVQLLYTINTAKSAKDAAEGLTFMREMAKWNSLSDFENGVIPAGVKIDDK-- 569
S++ L DGRVQL+ A S+ DA +GL FM+EM + +S E + P V+I
Sbjct: 598 SLIHLKDGRVQLVQHAIQAASSIDAEDGLRFMQEMIELSSQQQKEQQLPPRAVQIVSHPF 657
Query: 570 ----IFPAGPAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFGIAKRGHCTFA 625
+ AGPA FG +++ ++ + P + C+ + N E + + +RG C FA
Sbjct: 658 FGRVVLTAGPAQFGLDLSKHKETRGFVASSKPSNGCSELTNPEAVMGKIALIQRGQCMFA 717
Query: 626 QKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDG--NDDIEIPAVFLFSKEGEYLSN 683
+K RN+Q AG I+ID+ S+ +T LF M+GDG DDI+IP +FLFSKEG + +
Sbjct: 718 EKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPMLFLFSKEGSIILD 777
Query: 684 ALKNNPELTVTVGE 697
A++ E+ V + +
Sbjct: 778 AIREYEEVEVLLSD 791
>AF288393-1|AAG60613.1| 889|Homo sapiens C1orf22 protein.
Length = 889
Score = 737 bits (1822), Expect = 0.0
Identities = 365/734 (49%), Positives = 499/734 (67%), Gaps = 38/734 (5%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MF HAY YME+AYPADELMPL+C+GR +G PSRGD+DDALG F +
Sbjct: 16 MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLN 75
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF A++ V++DV+ D D+VVSVFETNIR+LGGLL H LA LK +QWYN+E
Sbjct: 76 KTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDE 135
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESR-----ETCTACAGTMILEMA 175
LL MA+ LG ++LPAFNT++G+P+ +INL+ GIR E+R +TCTACAGT+ILE A
Sbjct: 136 LLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRK-PEARTGTETDTCTACAGTLILEFA 194
Query: 176 ALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYE 235
AL+R TG I+E+ A K++D LW+ R R+S+L+G INIH+GDWVRKDSGVGAGIDSYYE
Sbjct: 195 ALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYE 254
Query: 236 YCLKAYILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPG 295
Y LKAY+LLGD+ +L RF HY+AIM+YIS+ P++L VH+H+P L +R +MDALLAF+PG
Sbjct: 255 YLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWMDALLAFFPG 314
Query: 296 LQVLLGDVRPAVETHEMLYQVMQRHTFIPEAFTSDFQVHWGQHPLRPEFLESTYFLHRAT 355
LQVL GD+RPA+ETHEMLYQV+++H F+PEAFT+DF+VHW QHPLRPEF ESTYFL++AT
Sbjct: 315 LQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRVHWAQHPLRPEFAESTYFLYKAT 374
Query: 356 EDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLFGDE 415
D +YL+VGKT+++ L ++ RVPCG+A++ DVRT +HEDRMDSF LAE FKYLY+LF D+
Sbjct: 375 GDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYLLFADK 434
Query: 416 KDFPIKLEDYVLTTEAHFLPLSLATVGKNTS--YFTLKIDDPDEDKYRKTCPNTASLVP- 472
+D +EDY+ TTEAH LPL L+T ++ S T + + D+ + TCPNT L P
Sbjct: 435 EDIIFDIEDYIFTTEAHLLPLWLSTTNQSISKKNTTSEYTELDDSNFDWTCPNTQILFPN 494
Query: 473 -----EKVRQPMRQLLGS--------------TAARPPARLRPL--NDPRQINALSDMGI 511
+ +R+P++ ++ + A+PP R R +P + L MG+
Sbjct: 495 DPLYAQSIREPLKNVVDKSCPRGIIRVEESFRSGAKPPLRARDFMATNPEHLEILKKMGV 554
Query: 512 SVLTLPDGRVQLLYTINTAKSAKDAAEGLTFMREMAKWNSLSDFENGVIPAGVKIDDK-- 569
S++ L DGRVQL+ A S+ DA +GL FM+EM + +S E + P V+I
Sbjct: 555 SLIHLKDGRVQLVQHAIQAASSIDAEDGLRFMQEMIELSSQQQKEQQLPPRAVQIVSHPF 614
Query: 570 ----IFPAGPAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFGIAKRGHCTFA 625
+ AGPA FG +++ ++ + P + C+ + N E + + +RG C FA
Sbjct: 615 FGRVVLTAGPAQFGLDLSKHKETRGFVASSKPSNGCSELTNPEAVMGKIALIQRGQCMFA 674
Query: 626 QKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDG--NDDIEIPAVFLFSKEGEYLSN 683
+K RN+Q AG I+ID+ S+ +T LF M+GDG DDI+IP +FLFSKEG + +
Sbjct: 675 EKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPMLFLFSKEGSIILD 734
Query: 684 ALKNNPELTVTVGE 697
A++ E+ V + +
Sbjct: 735 AIREYEEVEVLLSD 748
>D86967-1|BAA13203.2| 666|Homo sapiens KIAA0212 protein.
Length = 666
Score = 359 bits (883), Expect = 2e-98
Identities = 190/450 (42%), Positives = 278/450 (61%), Gaps = 18/450 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGI-TPSRGDMDDALGNFXXXXXXXXXXXXXM 59
MF Y YM +A+P DEL P+ C+GR PS +++D LGN+ M
Sbjct: 146 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 205
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIP--LLQWY 117
G+ SEF A++LVI VSFD+D V VFE IR+LG LLSAH + K ++ Y
Sbjct: 206 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 265
Query: 118 NNELLTMAEDLGKRVLPAF-NTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAA 176
+NELL MA DL R+LPAF NT TGIP+ ++NL+ G+ T + ETCTA AG++++E
Sbjct: 266 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNN-ETCTAGAGSLLVEFGI 324
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+RL G+ +E A +++ LW +R + L+G V+NI +G WV K SG+GAG+DS+YEY
Sbjct: 325 LSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEY 384
Query: 237 CLKAYILLGDEKYLARFTRHYNAIMKYISRG-----------PVMLAVHMHRPHLQSRNF 285
LK+YIL G+++ L F Y +I Y+ RG P+ + V+M L + +
Sbjct: 385 LLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMN-TW 443
Query: 286 MDALLAFWPGLQVLLGDVRPAVETHEMLYQVMQRHTFIPEAFTSDFQV-HWGQHPLRPEF 344
+D+L AF+PGLQVL+GDV A+ H Y + +R+ +PE + Q +PLRPE
Sbjct: 444 IDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVLFYPLRPEL 503
Query: 345 LESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAET 404
+ESTY L++AT++ YL VG +L++L+++T+V CGYA+++ V ++ EDRM+SF L+ET
Sbjct: 504 VESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSET 563
Query: 405 FKYLYMLFGDEKDFPIKLEDYVLTTEAHFL 434
KYLY+LF ++ Y+ TTE H +
Sbjct: 564 CKYLYLLFDEDNPVHKSGTRYMFTTEGHIV 593
>BC019088-1|AAH19088.1| 657|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 1 protein.
Length = 657
Score = 359 bits (883), Expect = 2e-98
Identities = 190/450 (42%), Positives = 278/450 (61%), Gaps = 18/450 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGI-TPSRGDMDDALGNFXXXXXXXXXXXXXM 59
MF Y YM +A+P DEL P+ C+GR PS +++D LGN+ M
Sbjct: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIP--LLQWY 117
G+ SEF A++LVI VSFD+D V VFE IR+LG LLSAH + K ++ Y
Sbjct: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256
Query: 118 NNELLTMAEDLGKRVLPAF-NTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAA 176
+NELL MA DL R+LPAF NT TGIP+ ++NL+ G+ T + ETCTA AG++++E
Sbjct: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNN-ETCTAGAGSLLVEFGI 315
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+RL G+ +E A +++ LW +R + L+G V+NI +G WV K SG+GAG+DS+YEY
Sbjct: 316 LSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEY 375
Query: 237 CLKAYILLGDEKYLARFTRHYNAIMKYISRG-----------PVMLAVHMHRPHLQSRNF 285
LK+YIL G+++ L F Y +I Y+ RG P+ + V+M L + +
Sbjct: 376 LLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMN-TW 434
Query: 286 MDALLAFWPGLQVLLGDVRPAVETHEMLYQVMQRHTFIPEAFTSDFQV-HWGQHPLRPEF 344
+D+L AF+PGLQVL+GDV A+ H Y + +R+ +PE + Q +PLRPE
Sbjct: 435 IDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVLFYPLRPEL 494
Query: 345 LESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAET 404
+ESTY L++AT++ YL VG +L++L+++T+V CGYA+++ V ++ EDRM+SF L+ET
Sbjct: 495 VESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSET 554
Query: 405 FKYLYMLFGDEKDFPIKLEDYVLTTEAHFL 434
KYLY+LF ++ Y+ TTE H +
Sbjct: 555 CKYLYLLFDEDNPVHKSGTRYMFTTEGHIV 584
>CR457266-1|CAG33547.1| 578|Homo sapiens C20orf31 protein.
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>BC016184-1|AAH16184.1| 578|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 2 protein.
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>BC001371-1|AAH01371.1| 578|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 2 protein.
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>AL356652-1|CAH73763.1| 578|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 2 protein.
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>AL135844-1|CAI19292.1| 578|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 2 protein.
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>AK023931-1|BAB14731.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ13869 fis, clone THYRO1001287, weakly similar to
MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
3.2.1.113). ).
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>AK001645-1|BAA91806.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10783 fis, clone NT2RP4000417, weakly similar to
MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
3.2.1.113). ).
Length = 578
Score = 316 bits (776), Expect = 2e-85
Identities = 166/415 (40%), Positives = 253/415 (60%), Gaps = 18/415 (4%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
MFYHAY +Y+ENA+P DEL PL+C G D G+F +G
Sbjct: 42 MFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALDTLLILG 89
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ SEF ++++ V FD D+ SVFETNIR++GGLLSAH+L++ ++ +
Sbjct: 90 NVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGP 149
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMILEMAALTRL 180
LL MAE+ +++LPAF T TG+P+G +NL HG+ E+ TCTA GT I+E A L+ L
Sbjct: 150 LLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP-GETPVTCTAGIGTFIVEFATLSSL 208
Query: 181 TGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKA 240
TG+P++E A ++ RLW+ R L+G I++ +G WV +D+G+GAG+DSY+EY +K
Sbjct: 209 TGDPVFEDVARVALMRLWESRSDIG-LVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKG 267
Query: 241 YILLGDEKYLARFTRHYNAIMKYISRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLL 300
ILL D+K +A F + AI Y L V M++ + S +L A+WPGLQ L+
Sbjct: 268 AILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTV-SMPVFQSLEAYWPGLQSLI 326
Query: 301 GDVRPAVETHEMLYQVMQRHTFIPEAFT--SDFQVHWGQ-HPLRPEFLESTYFLHRATED 357
GD+ A+ T Y V ++ +PE + + V + +PLRPE +ES +L+RAT D
Sbjct: 327 GDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGD 386
Query: 358 DHYLQVGKTVLKALQQHTRVPCGYASVNDVRTRAHEDRMDSFVLAETFKYLYMLF 412
L++G+ ++++++ ++V CG+A++ D+R ++RM+SF LAET KYLY+LF
Sbjct: 387 PTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLF 441
>BC105586-1|AAI05587.1| 242|Homo sapiens EDEM3 protein protein.
Length = 242
Score = 287 bits (704), Expect = 1e-76
Identities = 137/239 (57%), Positives = 176/239 (73%), Gaps = 6/239 (2%)
Query: 20 MPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMGDFSEFNHAIQLVIKDVSFD 79
MPL+C+GR +G PSRGD+DDALG F + EF A++ V++DV+ D
Sbjct: 1 MPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLD 60
Query: 80 QDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNELLTMAEDLGKRVLPAFNTS 139
D+VVSVFETNIR+LGGLL H LA LK +QWYN+ELL MA+ LG ++LPAFNT+
Sbjct: 61 NDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDELLQMAKQLGYKLLPAFNTT 120
Query: 140 TGIPHGKINLRHGIRDLTESR-----ETCTACAGTMILEMAALTRLTGNPIYEQKAHKSM 194
+G+P+ +INL+ GIR E+R +TCTACAGT+ILE AAL+R TG I+E+ A K++
Sbjct: 121 SGLPYPRINLKFGIRK-PEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKAL 179
Query: 195 DRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKAYILLGDEKYLARF 253
D LW+ R R+S+L+G INIH+GDWVRKDSGVGAGIDSYYEY LKAY+LLGD+ +L RF
Sbjct: 180 DFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERF 238
>AY358580-1|AAQ88943.1| 541|Homo sapiens C20orf31 protein.
Length = 541
Score = 283 bits (694), Expect = 2e-75
Identities = 149/383 (38%), Positives = 232/383 (60%), Gaps = 6/383 (1%)
Query: 33 PSRGDMDDALGNFXXXXXXXXXXXXXMGDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIR 92
P D A +F +G+ SEF ++++ V FD D+ SVFETNIR
Sbjct: 25 PDGSAPDPAHYSFSLTLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIR 84
Query: 93 MLGGLLSAHVLAETLKSDIPLLQWYNNELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHG 152
++GGLLSAH+L++ ++ + LL MAE+ +++LPAF T TG+P+G +NL HG
Sbjct: 85 VVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHG 144
Query: 153 IRDLTESRETCTACAGTMILEMAALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVI 212
+ E+ TCTA GT I+E A L+ LTG+P++E A ++ RLW+ R L+G I
Sbjct: 145 VNP-GETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIG-LVGNHI 202
Query: 213 NIHSGDWVRKDSGVGAGIDSYYEYCLKAYILLGDEKYLARFTRHYNAIMKYISRGPVMLA 272
++ +G WV +D+G+GAG+DSY+EY +K ILL D+K +A F + AI Y L
Sbjct: 203 DVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLW 262
Query: 273 VHMHRPHLQSRNFMDALLAFWPGLQVLLGDVRPAVETHEMLYQVMQRHTFIPEAFT--SD 330
V M++ + S +L A+WPGLQ L+GD+ A+ T Y V ++ +PE +
Sbjct: 263 VQMYKGTV-SMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQG 321
Query: 331 FQVHWGQ-HPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRT 389
+ V + +PLRPE +ES +L+RAT D L++G+ ++++++ ++V CG+A++ D+R
Sbjct: 322 YTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRD 381
Query: 390 RAHEDRMDSFVLAETFKYLYMLF 412
++RM+SF LAET KYLY+LF
Sbjct: 382 HKLDNRMESFFLAETVKYLYLLF 404
>BC006079-1|AAH06079.1| 699|Homo sapiens mannosidase, alpha, class
1B, member 1 protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>BC002953-1|AAH02953.1| 699|Homo sapiens mannosidase, alpha, class
1B, member 1 protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>AY358465-1|AAQ88830.1| 699|Homo sapiens MAN1B1 protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>AL929554-19|CAH72887.1| 699|Homo sapiens mannosidase, alpha, class
1B, member 1 protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>AL807752-35|CAI12781.1| 699|Homo sapiens mannosidase, alpha, class
1B, member 1 protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>AF148509-1|AAF03215.1| 699|Homo sapiens alpha 1,2-mannosidase
protein.
Length = 699
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 301
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 349
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 350 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 409
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 410 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 469
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 470 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 529
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 530 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 589
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 590 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 649
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 650 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 695
>AF145732-1|AAD45504.1| 663|Homo sapiens endoplasmic reticulum
alpha-mannosidase I protein.
Length = 663
Score = 164 bits (399), Expect = 1e-39
Identities = 142/467 (30%), Positives = 219/467 (46%), Gaps = 58/467 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCK-GRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXM 59
+F HA+ Y + A+ DEL P+S W G+ + D D + +
Sbjct: 220 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMW--------------IL 265
Query: 60 GDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
G EF A + V K + F++D+ V++FE+ IR+LGGLLSA+ L+ ++
Sbjct: 266 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSG------------DS 313
Query: 120 ELLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRETCTACAGTMI-LEMAALT 178
L AED G R++PAF T + IP+ +N+ G+ T T I LE L+
Sbjct: 314 LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELS 373
Query: 179 RLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGIDSYYEYC 237
RLTG+ +++ K + + + L+ IN HSG + +GA DSYYEY
Sbjct: 374 RLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYL 433
Query: 238 LKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFMDALLAFW 293
LK +I G + + L + + ++ R P L H + MD L+ F
Sbjct: 434 LKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFL 493
Query: 294 PGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFTSDFQVHW 335
PG L + A E E YQ+ ++ P+ D +V
Sbjct: 494 PGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKP 553
Query: 336 G--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH 392
+ LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+
Sbjct: 554 ADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQK 613
Query: 393 ---EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
D+M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 614 PEPRDKMESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 659
>X74837-1|CAA52831.1| 625|Homo sapiens Man9-mannosidase protein.
Length = 625
Score = 149 bits (362), Expect = 3e-35
Identities = 142/469 (30%), Positives = 219/469 (46%), Gaps = 63/469 (13%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA++ Y A+ +EL P+S KG G GN +
Sbjct: 174 MMKHAWNNYKGYAWGLNELKPIS-----KG-----GHSSSLFGNIKGATIVDALDTLFIM 223
Query: 61 DFS-EFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
+ EF A V +++ F+ + +SVFE NIR +GGLLSA+ L+
Sbjct: 224 EMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS-------------GE 270
Query: 120 ELLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMA 175
E+ A +LG ++LPAF+T +GIP +N++ GI + A GT+ LE
Sbjct: 271 EIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFM 330
Query: 176 ALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYE 235
L+ L+GNPI+ +K L K+ + L +N SG W + VG DS+YE
Sbjct: 331 HLSHLSGNPIFAEKVMNIRTVLNKLE-KPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYE 389
Query: 236 YCLKAYILLGDEKYLARFTRHYNAI-------MKYISRGPVMLAVHMHRPHLQSRNFMDA 288
Y LKA+ L+ D+ L +++A+ ++ S G +A R L+ + M
Sbjct: 390 YLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIA-EWKRGLLEHK--MGH 445
Query: 289 LLAFWPGLQVLLGDVRP-AVETH--EMLYQVMQ------RHTFI---PEAFTSDFQV--- 333
L F G+ L D P + H E+ ++ + TF+ PEAF D V
Sbjct: 446 LTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAI 505
Query: 334 ----HWGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRT 389
+ + LRPE +E+ ++ R T D Y + ++AL+ H RV GY+ + DV
Sbjct: 506 ATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYL 565
Query: 390 --RAHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
+++D SF LAET KYLY++F D+ P LE ++ +EAH LP+
Sbjct: 566 LHESYDDVQQSFFLAETLKYLYLIFSDDDLLP--LEHWIFNSEAHLLPI 612
>AL078600-1|CAB75695.2| 653|Homo sapiens mannosidase, alpha, class
1A, member 1 protein.
Length = 653
Score = 147 bits (357), Expect = 1e-34
Identities = 139/466 (29%), Positives = 213/466 (45%), Gaps = 57/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA++ Y A+ +EL P+S KG G GN +
Sbjct: 202 MMKHAWNNYKGYAWGLNELKPIS-----KG-----GHSSSLFGNIKGATIVDALDTLFIM 251
Query: 61 DFS-EFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
+ EF A V +++ F+ + +SVFE NIR +GGLLSA+ L+
Sbjct: 252 EMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS-------------GE 298
Query: 120 ELLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMA 175
E+ A +LG ++LPAF+T +GIP +N++ GI + A GT+ LE
Sbjct: 299 EIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFM 358
Query: 176 ALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYE 235
L+ L+GNPI+ +K L K+ + L +N SG W + VG DS+YE
Sbjct: 359 HLSHLSGNPIFAEKVMNIRTVLNKLE-KPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYE 417
Query: 236 YCLKAYILLGDEKYLARFTRHYNAIMKY----ISRGPVMLAVHMHRPHLQSRNFMDALLA 291
Y LKA+ L+ D+ L +++A+ I + L + M L
Sbjct: 418 YLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTC 476
Query: 292 FWPGLQVLLGDVRP-AVETH--EMLYQVMQ------RHTFI---PEAFTSDFQV------ 333
F G+ L D P + H E+ ++ + TF+ PEAF D V
Sbjct: 477 FAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATR 536
Query: 334 -HWGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRT--R 390
+ + LRPE +E+ ++ R T D Y + ++AL+ H RV GY+ + DV
Sbjct: 537 QNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHE 596
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
+++D SF LAET KYLY++F D+ P LE ++ +EAH LP+
Sbjct: 597 SYDDVQQSFFLAETLKYLYLIFSDDDLLP--LEHWIFNSEAHLLPI 640
>AL022722-2|CAI20315.1| 653|Homo sapiens mannosidase, alpha, class
1A, member 1 protein.
Length = 653
Score = 147 bits (357), Expect = 1e-34
Identities = 139/466 (29%), Positives = 213/466 (45%), Gaps = 57/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA++ Y A+ +EL P+S KG G GN +
Sbjct: 202 MMKHAWNNYKGYAWGLNELKPIS-----KG-----GHSSSLFGNIKGATIVDALDTLFIM 251
Query: 61 DFS-EFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
+ EF A V +++ F+ + +SVFE NIR +GGLLSA+ L+
Sbjct: 252 EMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS-------------GE 298
Query: 120 ELLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMA 175
E+ A +LG ++LPAF+T +GIP +N++ GI + A GT+ LE
Sbjct: 299 EIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFM 358
Query: 176 ALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYE 235
L+ L+GNPI+ +K L K+ + L +N SG W + VG DS+YE
Sbjct: 359 HLSHLSGNPIFAEKVMNIRTVLNKLE-KPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYE 417
Query: 236 YCLKAYILLGDEKYLARFTRHYNAIMKY----ISRGPVMLAVHMHRPHLQSRNFMDALLA 291
Y LKA+ L+ D+ L +++A+ I + L + M L
Sbjct: 418 YLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTC 476
Query: 292 FWPGLQVLLGDVRP-AVETH--EMLYQVMQ------RHTFI---PEAFTSDFQV------ 333
F G+ L D P + H E+ ++ + TF+ PEAF D V
Sbjct: 477 FAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATR 536
Query: 334 -HWGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDVRT--R 390
+ + LRPE +E+ ++ R T D Y + ++AL+ H RV GY+ + DV
Sbjct: 537 QNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHE 596
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
+++D SF LAET KYLY++F D+ P LE ++ +EAH LP+
Sbjct: 597 SYDDVQQSFFLAETLKYLYLIFSDDDLLP--LEHWIFNSEAHLLPI 640
>BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 146 bits (355), Expect = 2e-34
Identities = 139/466 (29%), Positives = 207/466 (44%), Gaps = 56/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA+ Y + +EL P++ KG I S MG
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS--------SQMGATIVDALDTLYIMG 238
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF + + ++ F + VSVFE NIR +GGLL+A+ L+ E
Sbjct: 239 LHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------GEE 285
Query: 121 LLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMAA 176
+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 286 IFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIH 345
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+ LTG+ Y +K L K+ R + L +N +G W + + VG DS+YEY
Sbjct: 346 LSYLTGDLTYYKKVMHIRKLLQKM-DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEY 404
Query: 237 CLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRPHLQSRNFMDALLA 291
LKA+++ + AR + AI K++ SRG + HL+ + M L
Sbjct: 405 LLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKK--MGHLAC 462
Query: 292 FWPGLQVLLGD----------VRPAVETHEMLYQVMQRHTFI--PEAFTSDFQVH----- 334
F G+ L D + E ++ R PE+F D V
Sbjct: 463 FAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVR 522
Query: 335 --WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTR 390
+ LRPE +E+ ++L R T D Y Q G A++++ RV G++ V DV T
Sbjct: 523 QAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTP 582
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
H+D SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 583 THDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 626
>AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 146 bits (355), Expect = 2e-34
Identities = 139/466 (29%), Positives = 207/466 (44%), Gaps = 56/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA+ Y + +EL P++ KG I S MG
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS--------SQMGATIVDALDTLYIMG 238
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF + + ++ F + VSVFE NIR +GGLL+A+ L+ E
Sbjct: 239 LHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------GEE 285
Query: 121 LLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMAA 176
+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 286 IFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIH 345
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+ LTG+ Y +K L K+ R + L +N +G W + + VG DS+YEY
Sbjct: 346 LSYLTGDLTYYKKVMHIRKLLQKM-DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEY 404
Query: 237 CLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRPHLQSRNFMDALLA 291
LKA+++ + AR + AI K++ SRG + HL+ + M L
Sbjct: 405 LLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKK--MGHLAC 462
Query: 292 FWPGLQVLLGD----------VRPAVETHEMLYQVMQRHTFI--PEAFTSDFQVH----- 334
F G+ L D + E ++ R PE+F D V
Sbjct: 463 FAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVR 522
Query: 335 --WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTR 390
+ LRPE +E+ ++L R T D Y Q G A++++ RV G++ V DV T
Sbjct: 523 QAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTP 582
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
H+D SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 583 THDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 626
>AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 146 bits (355), Expect = 2e-34
Identities = 139/466 (29%), Positives = 207/466 (44%), Gaps = 56/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA+ Y + +EL P++ KG I S MG
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS--------SQMGATIVDALDTLYIMG 238
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF + + ++ F + VSVFE NIR +GGLL+A+ L+ E
Sbjct: 239 LHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------GEE 285
Query: 121 LLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMAA 176
+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 286 IFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIH 345
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+ LTG+ Y +K L K+ R + L +N +G W + + VG DS+YEY
Sbjct: 346 LSYLTGDLTYYKKVMHIRKLLQKM-DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEY 404
Query: 237 CLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRPHLQSRNFMDALLA 291
LKA+++ + AR + AI K++ SRG + HL+ + M L
Sbjct: 405 LLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKK--MGHLAC 462
Query: 292 FWPGLQVLLGD----------VRPAVETHEMLYQVMQRHTFI--PEAFTSDFQVH----- 334
F G+ L D + E ++ R PE+F D V
Sbjct: 463 FAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVR 522
Query: 335 --WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTR 390
+ LRPE +E+ ++L R T D Y Q G A++++ RV G++ V DV T
Sbjct: 523 QAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTP 582
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
H+D SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 583 THDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 626
>AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase IB
protein.
Length = 641
Score = 146 bits (355), Expect = 2e-34
Identities = 139/466 (29%), Positives = 207/466 (44%), Gaps = 56/466 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA+ Y + +EL P++ KG I S MG
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS--------SQMGATIVDALDTLYIMG 238
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF + + ++ F + VSVFE NIR +GGLL+A+ L+ E
Sbjct: 239 LHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------GEE 285
Query: 121 LLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMAA 176
+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 286 IFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIH 345
Query: 177 LTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEY 236
L+ LTG+ Y +K L K+ R + L +N +G W + + VG DS+YEY
Sbjct: 346 LSYLTGDLTYYKKVMHIRKLLQKM-DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEY 404
Query: 237 CLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRPHLQSRNFMDALLA 291
LKA+++ + AR + AI K++ SRG + HL+ + M L
Sbjct: 405 LLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKK--MGHLAC 462
Query: 292 FWPGLQVLLGD----------VRPAVETHEMLYQVMQRHTFI--PEAFTSDFQVH----- 334
F G+ L D + E ++ R PE+F D V
Sbjct: 463 FAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVR 522
Query: 335 --WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTR 390
+ LRPE +E+ ++L R T D Y Q G A++++ RV G++ V DV T
Sbjct: 523 QAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTP 582
Query: 391 AHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
H+D SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 583 THDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 626
>AL031280-2|CAI19714.1| 630|Homo sapiens mannosidase, alpha, class
1C, member 1 protein.
Length = 630
Score = 138 bits (333), Expect = 1e-31
Identities = 138/465 (29%), Positives = 209/465 (44%), Gaps = 55/465 (11%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M A+ +Y A +EL PL+ G G+M L +
Sbjct: 181 MMQFAWQSYKRYAMGKNELRPLTKDGY-------EGNMFGGLSGATVIDSLDTLYLMELK 233
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ EF A V + + S+FE NIR +GGLLSA L I ++
Sbjct: 234 E--EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIR----- 286
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRD-LTESRETCTACAGTMILEMAALTR 179
LG+++LPAFNT TGIP G ++ + G T + A G++ LE LT
Sbjct: 287 -------LGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTE 339
Query: 180 LTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLK 239
L+GN ++ +K L KI + L ++ SG+WV+ VG DS+YEY +K
Sbjct: 340 LSGNQVFAEKVRNIRKVLRKIE-KPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIK 398
Query: 240 AYILLGDEKYLAR--FTRHYNAIMKY---ISRGPVMLAVHMHRPHLQSRNFMDALLAFWP 294
++++ G A+ + AI Y +S G + L + M L F
Sbjct: 399 SWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHK--MGHLACFSG 456
Query: 295 GLQVLLG--DVRPAVETH--EMLYQVMQR-HTFI--------PEAFTSDF-------QVH 334
G+ + LG D + H E+ Q+ + H PEAF + Q+
Sbjct: 457 GM-IALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLS 515
Query: 335 WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTRAH 392
+ LRPE +ES +L R T + Y + G V+ AL+++ R G++ + DV T H
Sbjct: 516 ESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNH 575
Query: 393 EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPLS 437
+++ SF LAET KYLY+LF + D + LED+V TEAH LP++
Sbjct: 576 DNKQQSFFLAETLKYLYLLFSE--DDLLSLEDWVFNTEAHPLPVN 618
>AL031280-1|CAI19713.1| 450|Homo sapiens mannosidase, alpha, class
1C, member 1 protein.
Length = 450
Score = 138 bits (333), Expect = 1e-31
Identities = 138/465 (29%), Positives = 209/465 (44%), Gaps = 55/465 (11%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M A+ +Y A +EL PL+ G G+M L +
Sbjct: 1 MMQFAWQSYKRYAMGKNELRPLTKDGY-------EGNMFGGLSGATVIDSLDTLYLMELK 53
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ EF A V + + S+FE NIR +GGLLSA L I ++
Sbjct: 54 E--EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIR----- 106
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRD-LTESRETCTACAGTMILEMAALTR 179
LG+++LPAFNT TGIP G ++ + G T + A G++ LE LT
Sbjct: 107 -------LGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTE 159
Query: 180 LTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLK 239
L+GN ++ +K L KI + L ++ SG+WV+ VG DS+YEY +K
Sbjct: 160 LSGNQVFAEKVRNIRKVLRKIE-KPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIK 218
Query: 240 AYILLGDEKYLAR--FTRHYNAIMKY---ISRGPVMLAVHMHRPHLQSRNFMDALLAFWP 294
++++ G A+ + AI Y +S G + L + M L F
Sbjct: 219 SWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHK--MGHLACFSG 276
Query: 295 GLQVLLG--DVRPAVETH--EMLYQVMQR-HTFI--------PEAFTSDF-------QVH 334
G+ + LG D + H E+ Q+ + H PEAF + Q+
Sbjct: 277 GM-IALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLS 335
Query: 335 WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTRAH 392
+ LRPE +ES +L R T + Y + G V+ AL+++ R G++ + DV T H
Sbjct: 336 ESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNH 395
Query: 393 EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPLS 437
+++ SF LAET KYLY+LF + D + LED+V TEAH LP++
Sbjct: 396 DNKQQSFFLAETLKYLYLLFSE--DDLLSLEDWVFNTEAHPLPVN 438
>AF261655-1|AAF97058.1| 630|Homo sapiens 1,2-alpha-mannosidase IC
protein.
Length = 630
Score = 138 bits (333), Expect = 1e-31
Identities = 138/465 (29%), Positives = 209/465 (44%), Gaps = 55/465 (11%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M A+ +Y A +EL PL+ G G+M L +
Sbjct: 181 MMQFAWQSYKRYAMGKNELRPLTKDGY-------EGNMFGGLSGATVIDSLDTLYLMELK 233
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ EF A V + + S+FE NIR +GGLLSA L I ++
Sbjct: 234 E--EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIR----- 286
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRD-LTESRETCTACAGTMILEMAALTR 179
LG+++LPAFNT TGIP G ++ + G T + A G++ LE LT
Sbjct: 287 -------LGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTE 339
Query: 180 LTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLK 239
L+GN ++ +K L KI + L ++ SG+WV+ VG DS+YEY +K
Sbjct: 340 LSGNQVFAEKVRNIRKVLRKIE-KPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIK 398
Query: 240 AYILLGDEKYLAR--FTRHYNAIMKY---ISRGPVMLAVHMHRPHLQSRNFMDALLAFWP 294
++++ G A+ + AI Y +S G + L + M L F
Sbjct: 399 SWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHK--MGHLACFSG 456
Query: 295 GLQVLLG--DVRPAVETH--EMLYQVMQR-HTFI--------PEAFTSDF-------QVH 334
G+ + LG D + H E+ Q+ + H PEAF + Q+
Sbjct: 457 GM-IALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLS 515
Query: 335 WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTRAH 392
+ LRPE +ES +L R T + Y + G V+ AL+++ R G++ + DV T H
Sbjct: 516 ESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNH 575
Query: 393 EDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPLS 437
+++ SF LAET KYLY+LF + D + LED+V TEAH LP++
Sbjct: 576 DNKQQSFFLAETLKYLYLLFSE--DDLLSLEDWVFNTEAHPLPVN 618
>AB209275-1|BAD92512.1| 482|Homo sapiens mannosidase, alpha, class
1C, member 1 variant protein.
Length = 482
Score = 108 bits (260), Expect = 7e-23
Identities = 122/434 (28%), Positives = 187/434 (43%), Gaps = 53/434 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M A+ +Y A +EL PL+ G G+M L +
Sbjct: 73 MMQFAWQSYKRYAMGKNELRPLTKDGY-------EGNMFGGLSGATVIDSLDTLYLMELK 125
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
+ EF A V + + S+FE NIR +GGLLSA L I ++
Sbjct: 126 E--EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIR----- 178
Query: 121 LLTMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRD-LTESRETCTACAGTMILEMAALTR 179
LG+++LPAFNT TGIP G ++ + G T + A G++ LE LT
Sbjct: 179 -------LGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTE 231
Query: 180 LTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYYEYCLK 239
L+GN ++ +K L KI + L ++ SG+WV+ VG DS+YEY +K
Sbjct: 232 LSGNQVFAEKVRNIRKVLRKI-EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIK 290
Query: 240 AYILLGDEKYLAR--FTRHYNAIMKY---ISRGPVMLAVHMHRPHLQSRNFMDALLAFWP 294
++++ G A+ + AI Y +S G + L + M L F
Sbjct: 291 SWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHK--MGHLACFSG 348
Query: 295 GLQVLLG--DVRPAVETH--EMLYQVMQR-HTFI--------PEAFTSD-------FQVH 334
G+ + LG D + H E+ Q+ + H PEAF + Q+
Sbjct: 349 GM-IALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLS 407
Query: 335 WGQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTRAH 392
+ LRPE +ES +L R T + Y + G V+ AL+++ R G++ + DV T H
Sbjct: 408 ESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNH 467
Query: 393 EDRMDSFVLAETFK 406
+++ SF LAET K
Sbjct: 468 DNKQQSFFLAETLK 481
>AL358072-2|CAH71080.1| 343|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 343
Score = 103 bits (246), Expect = 3e-21
Identities = 103/345 (29%), Positives = 155/345 (44%), Gaps = 44/345 (12%)
Query: 91 IRMLGGLLSAHVLAETLKSDIPLLQWYNNELLTMAEDLGKRVLPAFNTSTGIPHGKINLR 150
IR +GGLL+A+ L+ I +Q L +++LPAFNT TGIP +NL+
Sbjct: 1 IRFIGGLLAAYYLSGEEIFKIKAVQ------------LAEKLLPAFNTPTGIPWAMVNLK 48
Query: 151 HGIR---DLTESRETCTACAGTMILEMAALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDL 207
G+ + + A GT+ +E L+ LTG+ Y +K L K+ R + L
Sbjct: 49 SGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKM-DRPNGL 107
Query: 208 MGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKAYILLGDEKYLAR--FTRHYNAIMKYI- 264
+N +G W + + VG DS+YEY LKA+++ + AR + AI K++
Sbjct: 108 YPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLI 167
Query: 265 --SRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLLGD----------VRPAVETHEM 312
SRG + HL+ + M L F G+ L D + E
Sbjct: 168 KKSRGGLTFIGEWKNGHLEKK--MGHLACFAGGMFALGADGSRADKAGHYLELGAEIART 225
Query: 313 LYQVMQRHTFI--PEAFTSDFQVH-------WGQHPLRPEFLESTYFLHRATEDDHYLQV 363
++ R PE+F D V + LRPE +E+ ++L R T D Y Q
Sbjct: 226 CHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQW 285
Query: 364 GKTVLKALQQHTRVPCGYASVNDV--RTRAHEDRMDSFVLAETFK 406
G A++++ RV G++ V DV T H+D SF LAET K
Sbjct: 286 GWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLK 330
>AL157902-4|CAI22318.1| 343|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 343
Score = 103 bits (246), Expect = 3e-21
Identities = 103/345 (29%), Positives = 155/345 (44%), Gaps = 44/345 (12%)
Query: 91 IRMLGGLLSAHVLAETLKSDIPLLQWYNNELLTMAEDLGKRVLPAFNTSTGIPHGKINLR 150
IR +GGLL+A+ L+ I +Q L +++LPAFNT TGIP +NL+
Sbjct: 1 IRFIGGLLAAYYLSGEEIFKIKAVQ------------LAEKLLPAFNTPTGIPWAMVNLK 48
Query: 151 HGIR---DLTESRETCTACAGTMILEMAALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDL 207
G+ + + A GT+ +E L+ LTG+ Y +K L K+ R + L
Sbjct: 49 SGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKM-DRPNGL 107
Query: 208 MGTVINIHSGDWVRKDSGVGAGIDSYYEYCLKAYILLGDEKYLAR--FTRHYNAIMKYI- 264
+N +G W + + VG DS+YEY LKA+++ + AR + AI K++
Sbjct: 108 YPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLI 167
Query: 265 --SRGPVMLAVHMHRPHLQSRNFMDALLAFWPGLQVLLGD----------VRPAVETHEM 312
SRG + HL+ + M L F G+ L D + E
Sbjct: 168 KKSRGGLTFIGEWKNGHLEKK--MGHLACFAGGMFALGADGSRADKAGHYLELGAEIART 225
Query: 313 LYQVMQRHTFI--PEAFTSDFQVH-------WGQHPLRPEFLESTYFLHRATEDDHYLQV 363
++ R PE+F D V + LRPE +E+ ++L R T D Y Q
Sbjct: 226 CHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQW 285
Query: 364 GKTVLKALQQHTRVPCGYASVNDV--RTRAHEDRMDSFVLAETFK 406
G A++++ RV G++ V DV T H+D SF LAET K
Sbjct: 286 GWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLK 330
>AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens
cDNA FLJ13246 fis, clone OVARC1000682, highly similar to
PROCESSING ALPHA-1,2-MANNOSIDASE (EC 3.2.1.-). ).
Length = 618
Score = 89.8 bits (213), Expect = 3e-17
Identities = 78/253 (30%), Positives = 120/253 (47%), Gaps = 25/253 (9%)
Query: 59 MGDFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYN 118
MG EF + + ++ F + VSVFE NIR +GGLL+A+ L+
Sbjct: 27 MGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------G 73
Query: 119 NELLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEM 174
E+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 74 EEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEF 133
Query: 175 AALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDSGVGAGIDSYY 234
L+ LTG+ Y +K L K+ R + L +N +G W + + VG DS+Y
Sbjct: 134 IHLSYLTGDLTYYKKVMHIRKLLQKM-DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFY 192
Query: 235 EYCLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRPHLQSRNFMDAL 289
EY LKA+++ + AR + AI K++ SRG + HL+ + M L
Sbjct: 193 EYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKK--MGHL 250
Query: 290 LAFWPGLQVLLGD 302
F G+ L D
Sbjct: 251 ACFAGGMFALGAD 263
>AK074559-1|BAC11060.1| 178|Homo sapiens .2.1.113). protein.
Length = 178
Score = 84.6 bits (200), Expect = 1e-15
Identities = 44/101 (43%), Positives = 65/101 (64%), Gaps = 5/101 (4%)
Query: 340 LRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVNDVRTRAH---EDR 395
LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N+V+ D+
Sbjct: 75 LRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDK 134
Query: 396 MDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 135 MESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 174
>AF053626-1|AAC26201.1| 251|Homo sapiens alpha 1,2-mannosidase IB
protein.
Length = 251
Score = 83.8 bits (198), Expect = 2e-15
Identities = 77/239 (32%), Positives = 110/239 (46%), Gaps = 30/239 (12%)
Query: 224 SGVGAGIDSYYEYCLKAYILLGDEKYLAR--FTRHYNAIMKYI---SRGPVMLAVHMHRP 278
+ VG DS+YEY LKA+++ + AR + AI K++ SRG +
Sbjct: 2 TSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNG 61
Query: 279 HLQSRNFMDALLAFWPGLQVLLGDVRPA----------VETHEMLYQVMQRHTFI--PEA 326
HL+ + M L F G+ L D A E ++ R PE+
Sbjct: 62 HLEKK--MGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPES 119
Query: 327 FTSDFQVHW-------GQHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC 379
F D V + LRPE +E+ ++L R T D Y Q G A++++ RV
Sbjct: 120 FKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNG 179
Query: 380 GYASVNDV--RTRAHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
G++ V DV T H+D SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 180 GFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 236
>AB209276-1|BAD92513.1| 185|Homo sapiens alpha 1,2-mannosidase
variant protein.
Length = 185
Score = 83.8 bits (198), Expect = 2e-15
Identities = 44/101 (43%), Positives = 64/101 (63%), Gaps = 5/101 (4%)
Query: 340 LRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPC-GYASVN---DVRTRAHEDR 395
LRPE +ES ++L+R T D Y G +L++ + TRVP GY+S+N D + D+
Sbjct: 82 LRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNAQDPQKPEPRDK 141
Query: 396 MDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
M+SF L ET KYL++LF D+ + + L+ YV TEAH LP+
Sbjct: 142 MESFFLGETLKYLFLLFSDDPNL-LSLDAYVFNTEAHPLPI 181
>AL157902-2|CAI22316.1| 203|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 203
Score = 78.6 bits (185), Expect = 8e-14
Identities = 43/99 (43%), Positives = 59/99 (59%), Gaps = 4/99 (4%)
Query: 340 LRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRVPCGYASVNDV--RTRAHEDRMD 397
LRPE +E+ ++L R T D Y Q G A++++ RV G++ V DV T H+D
Sbjct: 96 LRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQ 155
Query: 398 SFVLAETFKYLYMLFGDEKDFPIKLEDYVLTTEAHFLPL 436
SF LAET KYLY+LF + P L+ +V TEAH LP+
Sbjct: 156 SFFLAETLKYLYLLFSGDDLLP--LDHWVFNTEAHPLPV 192
>AL096819-2|CAI21740.1| 155|Homo sapiens ER degradation enhancer,
mannosidase alpha-like 3 protein.
Length = 155
Score = 76.2 bits (179), Expect = 4e-13
Identities = 33/45 (73%), Positives = 38/45 (84%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNF 45
MF HAY YME+AYPADELMPL+C+GR +G PSRGD+DDALG F
Sbjct: 59 MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103
>AK023095-1|BAB14402.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ13033 fis, clone NT2RP3001126. ).
Length = 155
Score = 76.2 bits (179), Expect = 4e-13
Identities = 33/45 (73%), Positives = 38/45 (84%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNF 45
MF HAY YME+AYPADELMPL+C+GR +G PSRGD+DDALG F
Sbjct: 59 MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103
>AF053621-1|AAC26200.1| 358|Homo sapiens alpha 1,2-mannosidase IB
protein.
Length = 358
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 25/193 (12%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA+ Y + +EL P++ KG I S MG
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS--------SQMGATIVDALDTLYIMG 238
Query: 61 DFSEFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNNE 120
EF + + ++ F + VSVFE NIR +GGLL+A+ L+ E
Sbjct: 239 LHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLS-------------GEE 285
Query: 121 LLTM-AEDLGKRVLPAFNTSTGIPHGKINLRHGIR---DLTESRETCTACAGTMILEMAA 176
+ + A L +++LPAFNT TGIP +NL+ G+ + + A GT+ +E
Sbjct: 286 IFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIH 345
Query: 177 LTRLTGNPIYEQK 189
L+ LTG+ Y +K
Sbjct: 346 LSYLTGDLTYYKK 358
>AL929554-1|CAH72871.2| 329|Homo sapiens mannosidase, alpha, class
1B, member 1 protein.
Length = 329
Score = 60.1 bits (139), Expect = 3e-08
Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 25/231 (10%)
Query: 172 LEMAALTRLTGNPIYEQKAHKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKD-SGVGAGI 230
LE L+RLTG+ +++ K + + + L+ IN HSG + +GA
Sbjct: 1 LEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARA 60
Query: 231 DSYYEYCLKAYILLG--DEKYLARFTRHYNAIMKYISR--GPVMLAVHMHRPHLQSRNFM 286
DSYYEY LK +I G + + L + + ++ R P L H + M
Sbjct: 61 DSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKM 120
Query: 287 DALLAFWPGLQVL-------LGDVRPAVETHEMLYQVMQR-----------HTFIPEAFT 328
D L+ F PG L + A E E YQ+ ++ P+
Sbjct: 121 DHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGR 180
Query: 329 SDFQVHWG--QHPLRPEFLESTYFLHRATEDDHYLQVGKTVLKALQQHTRV 377
D +V + LRPE +ES ++L+R T D Y G +L++ + TRV
Sbjct: 181 RDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRV 231
>BC065827-1|AAH65827.1| 367|Homo sapiens MAN1A1 protein protein.
Length = 367
Score = 56.0 bits (129), Expect = 5e-07
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 25/163 (15%)
Query: 1 MFYHAYHAYMENAYPADELMPLSCKGRWKGITPSRGDMDDALGNFXXXXXXXXXXXXXMG 60
M HA++ Y A+ +EL P+S KG G GN +
Sbjct: 225 MMKHAWNNYKGYAWGLNELKPIS-----KG-----GHSSSLFGNIKGATIVDALDTLFIM 274
Query: 61 DFS-EFNHAIQLVIKDVSFDQDIVVSVFETNIRMLGGLLSAHVLAETLKSDIPLLQWYNN 119
+ EF A V +++ F+ + +SVFE NIR +GGLLSA+ L+
Sbjct: 275 EMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS-------------GE 321
Query: 120 ELL-TMAEDLGKRVLPAFNTSTGIPHGKINLRHGIRDLTESRE 161
E+ A +LG ++LPAF+T +GIP +N++ + ++ + E
Sbjct: 322 EIFRKKAVELGVKLLPAFHTPSGIPWALLNMKRWMCNIPRAME 364
>AL157902-3|CAI22317.1| 97|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 97
Score = 55.2 bits (127), Expect = 9e-07
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 4/67 (5%)
Query: 372 QQHTRVPCGYASVNDV--RTRAHEDRMDSFVLAETFKYLYMLFGDEKDFPIKLEDYVLTT 429
+++ RV G++ V DV T H+D SF LAET KYLY+LF + P L+ +V T
Sbjct: 1 EKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLP--LDHWVFNT 58
Query: 430 EAHFLPL 436
EAH LP+
Sbjct: 59 EAHPLPV 65
>BC005069-1|AAH05069.1| 188|Homo sapiens chromosome 2 open reading
frame 7 protein.
Length = 188
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Query: 570 IFPAGPAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFGIAKRGHCTFAQKVR 629
IF A PA I L P +AC + N I + + +RG C+F K R
Sbjct: 43 IFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTR 102
Query: 630 NMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNN 688
+Q+ G + II DN D+ + S D IPA+FL ++G + +L+ +
Sbjct: 103 VVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTAD--IPALFLLGRDGYMIRRSLEQH 159
>AY358605-1|AAQ88968.1| 188|Homo sapiens C2orf7 protein.
Length = 188
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Query: 570 IFPAGPAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFGIAKRGHCTFAQKVR 629
IF A PA I L P +AC + N I + + +RG C+F K R
Sbjct: 43 IFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTR 102
Query: 630 NMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNN 688
+Q+ G + II DN D+ + S D IPA+FL ++G + +L+ +
Sbjct: 103 VVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTAD--IPALFLLGRDGYMIRRSLEQH 159
>AC010913-2|AAX88901.1| 188|Homo sapiens unknown protein.
Length = 188
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Query: 570 IFPAGPAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFGIAKRGHCTFAQKVR 629
IF A PA I L P +AC + N I + + +RG C+F K R
Sbjct: 43 IFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTR 102
Query: 630 NMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNN 688
+Q+ G + II DN D+ + S D IPA+FL ++G + +L+ +
Sbjct: 103 VVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTAD--IPALFLLGRDGYMIRRSLEQH 159
>CR457340-1|CAG33621.1| 350|Homo sapiens DKFZP566H073 protein.
Length = 350
Score = 40.3 bits (90), Expect = 0.027
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEIS-NG---FGIAKRGHCTFAQKVRN 630
PA FG ++ E L P +AC+P+ NG + +R C F KV N
Sbjct: 42 PALFGATLS-QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLN 100
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYL 681
QKAG A ++ N+ +++E + S + I IP+VF+ + EYL
Sbjct: 101 AQKAGYG-AAVVHNV--NSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 148
>BC010139-1|AAH10139.1| 350|Homo sapiens ring finger protein 167
protein.
Length = 350
Score = 40.3 bits (90), Expect = 0.027
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEIS-NG---FGIAKRGHCTFAQKVRN 630
PA FG ++ E L P +AC+P+ NG + +R C F KV N
Sbjct: 42 PALFGATLS-QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLN 100
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYL 681
QKAG A ++ N+ +++E + S + I IP+VF+ + EYL
Sbjct: 101 AQKAGYG-AAVVHNV--NSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 148
>AL834284-1|CAD38958.1| 349|Homo sapiens hypothetical protein
protein.
Length = 349
Score = 40.3 bits (90), Expect = 0.027
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEIS-NG---FGIAKRGHCTFAQKVRN 630
PA FG ++ E L P +AC+P+ NG + +R C F KV N
Sbjct: 42 PALFGATLS-QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLN 100
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYL 681
QKAG A ++ N+ +++E + S + I IP+VF+ + EYL
Sbjct: 101 AQKAGYG-AAVVHNV--NSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 148
>AL050060-1|CAB43253.1| 324|Homo sapiens hypothetical protein
protein.
Length = 324
Score = 40.3 bits (90), Expect = 0.027
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEIS-NG---FGIAKRGHCTFAQKVRN 630
PA FG ++ E L P +AC+P+ NG + +R C F KV N
Sbjct: 17 PALFGATLS-QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLN 75
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYL 681
QKAG A ++ N+ +++E + S + I IP+VF+ + EYL
Sbjct: 76 AQKAGYG-AAVVHNV--NSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 123
>AK025329-1|BAB15113.1| 350|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21676 fis, clone COL09164. ).
Length = 350
Score = 40.3 bits (90), Expect = 0.027
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEIS-NG---FGIAKRGHCTFAQKVRN 630
PA FG ++ E L P +AC+P+ NG + +R C F KV N
Sbjct: 42 PALFGATLS-QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLN 100
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYL 681
QKAG A ++ N+ +++E + S + I IP+VF+ + EYL
Sbjct: 101 AQKAGYG-AAVVHNV--NSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 148
>AC005764-1|AAC62428.1| 420|Homo sapiens R31343_1 protein.
Length = 420
Score = 40.3 bits (90), Expect = 0.027
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG---IAKRGHCTFAQKVRNM 631
PA FG + E L V P +AC P+E + G + +R CTF KV N
Sbjct: 108 PALFGVPLAP-EGIRGYLMEVKPANACHPIEAPRLGNRSLGAIVLIRRYDCTFDLKVLNA 166
Query: 632 QKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFL 673
Q+AG + AI+ + D T ++ D I IP+VF+
Sbjct: 167 QRAGFEAAIVHNVHSDDLVSMTHVYE---DLRGQIAIPSVFV 205
>BC101992-1|AAI01993.1| 314|Homo sapiens RNF150 protein protein.
Length = 314
Score = 38.7 bits (86), Expect = 0.083
Identities = 29/97 (29%), Positives = 54/97 (55%), Gaps = 13/97 (13%)
Query: 612 NGFGIAKRGHCTFAQKVRN--MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIP 669
N + +G+CT+ K+RN +Q A A++I N+ +T+ET M G +D I
Sbjct: 25 NWIALIPKGNCTYRDKIRNAFLQNAS---AVVIFNVGSNTNET---ITMPHAGVED--IV 76
Query: 670 AVFLFSKEGEYLSNALKNNPELT--VTVGELKNLKKH 704
A+ + +G+ + + L+ N +T +T+G +NL+K+
Sbjct: 77 AIMIPEPKGKEIVSLLERNITVTMYITIG-TRNLQKY 112
>BC017592-1|AAH17592.2| 429|Homo sapiens zinc and ring finger 4
protein.
Length = 429
Score = 38.7 bits (86), Expect = 0.083
Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG-IAKRGH--CTFAQKVRNM 631
PA FG + E L V P +AC P+E + G IA H CTF KV N
Sbjct: 117 PALFGVPLAP-EGIRGYLMEVKPANACHPIEAPRLGNRSLGSIALIRHYDCTFDLKVLNA 175
Query: 632 QKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFL 673
Q+AG + AI+ + D T ++ D I IP+VF+
Sbjct: 176 QRAGFEAAIVHNVHSDDLVSMTHVYE---DLRGQIAIPSVFV 214
>AB033040-1|BAA86528.1| 462|Homo sapiens KIAA1214 protein protein.
Length = 462
Score = 38.7 bits (86), Expect = 0.083
Identities = 29/97 (29%), Positives = 54/97 (55%), Gaps = 13/97 (13%)
Query: 612 NGFGIAKRGHCTFAQKVRN--MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIP 669
N + +G+CT+ K+RN +Q A A++I N+ +T+ET M G +D I
Sbjct: 182 NWIALIPKGNCTYRDKIRNAFLQNAS---AVVIFNVGSNTNET---ITMPHAGVED--IV 233
Query: 670 AVFLFSKEGEYLSNALKNNPELT--VTVGELKNLKKH 704
A+ + +G+ + + L+ N +T +T+G +NL+K+
Sbjct: 234 AIMIPEPKGKEIVSLLERNITVTMYITIG-TRNLQKY 269
>CR456804-1|CAG33085.1| 381|Homo sapiens RNF13 protein.
Length = 381
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>BC017878-1|AAH17878.1| 291|Homo sapiens RNF13 protein protein.
Length = 291
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>BC009803-1|AAH09803.1| 381|Homo sapiens ring finger protein 13
protein.
Length = 381
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>BC009781-1|AAH09781.1| 381|Homo sapiens ring finger protein 13
protein.
Length = 381
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>AF070558-1|AAC28641.1| 381|Homo sapiens RING zinc finger protein
RZF protein.
Length = 381
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>AF037204-1|AAC03769.1| 381|Homo sapiens RING zinc finger protein
protein.
Length = 381
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 575 PAHFGKEITGNERHTNTLTFVTPIDACTPVENEEEISNGFG----IAKRGHCTFAQKVRN 630
PA FG + E L P +AC P+ N G + +R C F KV N
Sbjct: 52 PARFGYRLPA-EGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLN 110
Query: 631 MQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFSKEGEYLSNALKN 687
Q+AG K A I+ N+ + + ++ + + I+IP+VF+ GE +N+LK+
Sbjct: 111 AQRAGYK-AAIVHNV--DSDDLISMGSNDIEVLKKIDIPSVFI----GESSANSLKD 160
>BC019353-1|AAH19353.1| 254|Homo sapiens Unknown (protein for
IMAGE:3943661) protein.
Length = 254
Score = 33.5 bits (73), Expect = 3.1
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 455 PDEDKYRKTCPNTASLVPEKVRQPMRQLLGSTAARPPARLRPLNDPRQINALSDMGISVL 514
P K P A L+P + P R+L + A PP P PR+ +A ++GI +
Sbjct: 5 PASPSAAKPRPGLAPLLPPERAMPPREL---SEAEPPPLRAPTPPPRRRSAPPELGIKCV 61
Query: 515 TLPDGRV 521
+ DG V
Sbjct: 62 LVGDGAV 68
>AL606833-2|CAI41229.1| 249|Homo sapiens ring finger protein 128
protein.
Length = 249
Score = 32.7 bits (71), Expect = 5.4
Identities = 17/80 (21%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 616 IAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFS 675
+ +RG+CTF++K++ + A++I N P++ ++T M+ G ++I A+ + +
Sbjct: 67 LIERGNCTFSEKIQTAGRRNAD-AVVIYNAPETGNQT---IQMANFG--AVDIVAIMIGN 120
Query: 676 KEGEYLSNALKNNPELTVTV 695
+G + +++ ++T+ +
Sbjct: 121 LKGTKILQSIQRGIQVTMVI 140
>AL606833-1|CAI41228.1| 402|Homo sapiens ring finger protein 128
protein.
Length = 402
Score = 32.7 bits (71), Expect = 5.4
Identities = 17/80 (21%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 616 IAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFS 675
+ +RG+CTF++K++ + A++I N P++ ++T M+ G ++I A+ + +
Sbjct: 94 LIERGNCTFSEKIQTAGRRNAD-AVVIYNAPETGNQT---IQMANFG--AVDIVAIMIGN 147
Query: 676 KEGEYLSNALKNNPELTVTV 695
+G + +++ ++T+ +
Sbjct: 148 LKGTKILQSIQRGIQVTMVI 167
>AL391315-3|CAI39547.1| 249|Homo sapiens ring finger protein 128
protein.
Length = 249
Score = 32.7 bits (71), Expect = 5.4
Identities = 17/80 (21%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 616 IAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFS 675
+ +RG+CTF++K++ + A++I N P++ ++T M+ G ++I A+ + +
Sbjct: 67 LIERGNCTFSEKIQTAGRRNAD-AVVIYNAPETGNQT---IQMANFG--AVDIVAIMIGN 120
Query: 676 KEGEYLSNALKNNPELTVTV 695
+G + +++ ++T+ +
Sbjct: 121 LKGTKILQSIQRGIQVTMVI 140
>AL391315-2|CAI39546.1| 402|Homo sapiens ring finger protein 128
protein.
Length = 402
Score = 32.7 bits (71), Expect = 5.4
Identities = 17/80 (21%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 616 IAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFS 675
+ +RG+CTF++K++ + A++I N P++ ++T M+ G ++I A+ + +
Sbjct: 94 LIERGNCTFSEKIQTAGRRNAD-AVVIYNAPETGNQT---IQMANFG--AVDIVAIMIGN 147
Query: 676 KEGEYLSNALKNNPELTVTV 695
+G + +++ ++T+ +
Sbjct: 148 LKGTKILQSIQRGIQVTMVI 167
>AK126553-1|BAC86589.1| 402|Homo sapiens protein ( Homo sapiens
cDNA FLJ44589 fis, clone BEAST2000981, weakly similar
to Mus musculus ring finger protein 130 (Rnf130). ).
Length = 402
Score = 32.7 bits (71), Expect = 5.4
Identities = 17/80 (21%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 616 IAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTALFAMSGDGNDDIEIPAVFLFS 675
+ +RG+CTF++K++ + A++I N P++ ++T M+ G ++I A+ + +
Sbjct: 94 LIERGNCTFSEKIQTAGRRNAD-AVVIYNAPETGNQT---IQMANFG--AVDIVAIMIGN 147
Query: 676 KEGEYLSNALKNNPELTVTV 695
+G + +++ ++T+ +
Sbjct: 148 LKGTKILQSIQRGIQVTMVI 167
>AK127005-1|BAC86786.1| 223|Homo sapiens protein ( Homo sapiens
cDNA FLJ45060 fis, clone BRAWH3023415, highly similar
to Homo sapiens alpha 1,2-mannosidase (LOC51697). ).
Length = 223
Score = 32.3 bits (70), Expect = 7.2
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Query: 183 NPIYEQKA-HKSMDRLWKIRHRTSDLMGTVINIHSGDWVRKDS-GVGAGIDSYYEYCLKA 240
+P Q+A K + + + L+ IN HSG + +GA DSYYEY LK
Sbjct: 86 SPFLPQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQ 145
Query: 241 YILLGDEK 248
+I G ++
Sbjct: 146 WIQGGKQE 153
>AK027295-1|BAB55021.1| 350|Homo sapiens protein ( Homo sapiens
cDNA FLJ14389 fis, clone HEMBA1002876. ).
Length = 350
Score = 32.3 bits (70), Expect = 7.2
Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 711 EGGCEAVVDSQNLPADKESFDH-LKKVLSQLVAQFELSLSNEEGNTQNSCAEEIAESIHL 769
E G EA+ Q A+K + L K+ SQ ++ NT N+C E A + H
Sbjct: 230 EFGEEALNSLQKTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNACMETEAVNYHD 289
Query: 770 EKGEFVHNV 778
E GE + N+
Sbjct: 290 ETGEIMDNL 298
>BC131536-1|AAI31537.1| 1631|Homo sapiens IQ motif containing GTPase
activating protein 3 protein.
Length = 1631
Score = 31.9 bits (69), Expect = 9.5
Identities = 16/32 (50%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 602 TPVENEEEISNGFGIAKRGHCTFAQKVRNMQK 633
+PVE EE + NG +AK GHC FA V ++K
Sbjct: 54 SPVELEESLRNGVLLAKLGHC-FAPSVVPLKK 84
>BC022038-1|AAH22038.1| 376|Homo sapiens ring finger protein 133
protein.
Length = 376
Score = 31.9 bits (69), Expect = 9.5
Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 599 DACTP--VENEEEISNGF-GIAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTAL 655
+AC P + + + S + + +RG CTF QK++ + G +II N+P + ++ +
Sbjct: 84 NACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGAS-GVIIYNVPGTGNQ---V 139
Query: 656 FAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNNPELTVTV 695
F M +D+ + V + + +G + + +K +T V
Sbjct: 140 FPMFHQAFEDVVV--VMIGNLKGTEIFHLIKKGVLITAVV 177
>AY253300-1|AAP06954.1| 1631|Homo sapiens IQGAP3 protein.
Length = 1631
Score = 31.9 bits (69), Expect = 9.5
Identities = 16/32 (50%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 602 TPVENEEEISNGFGIAKRGHCTFAQKVRNMQK 633
+PVE EE + NG +AK GHC FA V ++K
Sbjct: 54 SPVELEESLRNGVLLAKLGHC-FAPSVVPLKK 84
>AL365181-1|CAI13046.1| 1631|Homo sapiens IQ motif containing GTPase
activating protein 3 protein.
Length = 1631
Score = 31.9 bits (69), Expect = 9.5
Identities = 16/32 (50%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 602 TPVENEEEISNGFGIAKRGHCTFAQKVRNMQK 633
+PVE EE + NG +AK GHC FA V ++K
Sbjct: 54 SPVELEESLRNGVLLAKLGHC-FAPSVVPLKK 84
>AK098524-1|BAC05321.1| 376|Homo sapiens protein ( Homo sapiens
cDNA FLJ25658 fis, clone TST00370. ).
Length = 376
Score = 31.9 bits (69), Expect = 9.5
Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 599 DACTP--VENEEEISNGF-GIAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTAL 655
+AC P + + + S + + +RG CTF QK++ + G +II N+P + ++ +
Sbjct: 84 NACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGAS-GVIIYNVPGTGNQ---V 139
Query: 656 FAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNNPELTVTV 695
F M +D+ + V + + +G + + +K +T V
Sbjct: 140 FPMFHQAFEDVVV--VMIGNLKGTEIFHLIKKGVLITAVV 177
>AF447589-1|AAM22872.1| 376|Homo sapiens unknown protein.
Length = 376
Score = 31.9 bits (69), Expect = 9.5
Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 599 DACTP--VENEEEISNGF-GIAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTAL 655
+AC P + + + S + + +RG CTF QK++ + G +II N+P + ++ +
Sbjct: 84 NACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGAS-GVIIYNVPGTGNQ---V 139
Query: 656 FAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNNPELTVTV 695
F M +D+ + V + + +G + + +K +T V
Sbjct: 140 FPMFHQAFEDVVV--VMIGNLKGTEIFHLIKKGVLITAVV 177
>AC006463-1|AAQ96858.1| 376|Homo sapiens unknown protein.
Length = 376
Score = 31.9 bits (69), Expect = 9.5
Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 599 DACTP--VENEEEISNGF-GIAKRGHCTFAQKVRNMQKAGVKLAIIIDNIPDSTHETTAL 655
+AC P + + + S + + +RG CTF QK++ + G +II N+P + ++ +
Sbjct: 84 NACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGAS-GVIIYNVPGTGNQ---V 139
Query: 656 FAMSGDGNDDIEIPAVFLFSKEGEYLSNALKNNPELTVTV 695
F M +D+ + V + + +G + + +K +T V
Sbjct: 140 FPMFHQAFEDVVV--VMIGNLKGTEIFHLIKKGVLITAVV 177
>AB105103-1|BAC78211.1| 1631|Homo sapiens IQGAP3 protein.
Length = 1631
Score = 31.9 bits (69), Expect = 9.5
Identities = 16/32 (50%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 602 TPVENEEEISNGFGIAKRGHCTFAQKVRNMQK 633
+PVE EE + NG +AK GHC FA V ++K
Sbjct: 54 SPVELEESLRNGVLLAKLGHC-FAPSVVPLKK 84
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.134 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,880,278
Number of Sequences: 224733
Number of extensions: 4709248
Number of successful extensions: 10283
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 10017
Number of HSP's gapped (non-prelim): 131
length of query: 822
length of database: 73,234,838
effective HSP length: 96
effective length of query: 726
effective length of database: 51,660,470
effective search space: 37505501220
effective search space used: 37505501220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)
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