BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000688-TA|BGIBMGA000688-PA|IPR004481|K+-dependent Na+/Ca+ exchanger related-protein, IPR004837|Sodium/calcium exchanger membrane region (427 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch... 423 e-117 UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car... 418 e-115 UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car... 295 2e-78 UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve... 278 2e-73 UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr... 268 1e-70 UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-... 268 2e-70 UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang... 263 7e-69 UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas... 255 1e-66 UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.... 215 2e-54 UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n... 214 3e-54 UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast... 210 4e-53 UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb... 207 5e-52 UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-... 205 2e-51 UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch... 202 1e-50 UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1... 195 2e-48 UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch... 194 3e-48 UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr... 194 3e-48 UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve... 194 5e-48 UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ... 186 7e-46 UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut... 169 1e-40 UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx... 169 2e-40 UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot... 167 6e-40 UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-... 166 9e-40 UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N... 166 1e-39 UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve... 164 5e-39 UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha... 164 5e-39 UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch... 163 6e-39 UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh... 163 1e-38 UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto... 162 2e-38 UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor... 162 2e-38 UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass... 162 2e-38 UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N... 162 2e-38 UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang... 160 7e-38 UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M... 160 7e-38 UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch... 159 1e-37 UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr... 158 2e-37 UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve... 158 3e-37 UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s... 157 7e-37 UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:... 155 2e-36 UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang... 155 2e-36 UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|... 155 2e-36 UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch... 154 4e-36 UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;... 149 2e-34 UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang... 148 2e-34 UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr... 148 3e-34 UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ... 146 7e-34 UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure... 144 3e-33 UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve... 144 5e-33 UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang... 141 4e-32 UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger... 141 4e-32 UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci... 140 6e-32 UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste... 135 2e-30 UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependen... 130 9e-29 UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,... 128 3e-28 UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof... 126 8e-28 UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu... 121 4e-26 UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc... 112 2e-23 UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to potassium-... 107 4e-22 UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061... 104 5e-21 UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip... 83 1e-14 UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-... 83 2e-14 UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128, w... 78 5e-13 UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium d... 71 8e-11 UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal... 70 1e-10 UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ... 70 1e-10 UniRef50_UPI000023E8AF Cluster: hypothetical protein FG08070.1; ... 69 2e-10 UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve... 69 3e-10 UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep... 68 5e-10 UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ... 68 5e-10 UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen... 67 7e-10 UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;... 67 7e-10 UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob... 66 2e-09 UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus... 66 2e-09 UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re... 65 3e-09 UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole geno... 65 3e-09 UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ... 65 3e-09 UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 64 5e-09 UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ... 64 5e-09 UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6; ... 64 5e-09 UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7 pre... 64 5e-09 UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:... 64 7e-09 UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1; ... 64 7e-09 UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F... 64 9e-09 UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy... 64 9e-09 UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre... 64 9e-09 UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;... 63 1e-08 UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th... 63 1e-08 UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote... 63 2e-08 UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyce... 63 2e-08 UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2; ... 63 2e-08 UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na... 62 2e-08 UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr... 62 3e-08 UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote... 62 3e-08 UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces cap... 62 3e-08 UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ... 62 4e-08 UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 62 4e-08 UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ... 62 4e-08 UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C... 62 4e-08 UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to sodium-cal... 61 6e-08 UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 61 6e-08 UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ... 61 6e-08 UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 60 8e-08 UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve... 60 8e-08 UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella ve... 60 8e-08 UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces c... 60 8e-08 UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida albi... 60 8e-08 UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2; ... 60 8e-08 UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph... 60 1e-07 UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07 UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2; ... 60 1e-07 UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07 UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 60 1e-07 UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07 UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1; Schizosa... 60 1e-07 UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-... 59 2e-07 UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm... 59 2e-07 UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ... 59 2e-07 UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07 UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1; Methanobrevib... 59 2e-07 UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu... 59 3e-07 UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 59 3e-07 UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 59 3e-07 UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorha... 59 3e-07 UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob... 58 3e-07 UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 3e-07 UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 3e-07 UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor... 58 3e-07 UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte... 58 4e-07 UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 4e-07 UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 4e-07 UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 6e-07 UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac... 58 6e-07 UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium... 58 6e-07 UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N... 58 6e-07 UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein... 57 8e-07 UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T... 57 8e-07 UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein... 57 8e-07 UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 57 8e-07 UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ... 57 8e-07 UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1; ... 57 8e-07 UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2; ... 57 8e-07 UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ... 57 8e-07 UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 57 1e-06 UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A... 57 1e-06 UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|... 57 1e-06 UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome s... 56 1e-06 UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep... 56 1e-06 UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob... 56 1e-06 UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr... 56 1e-06 UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ... 56 1e-06 UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein... 56 1e-06 UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Ar... 56 1e-06 UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, wh... 56 1e-06 UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 56 1e-06 UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ... 56 2e-06 UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R... 56 2e-06 UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat... 56 2e-06 UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04... 56 2e-06 UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria... 56 2e-06 UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;... 56 2e-06 UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M... 56 2e-06 UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N... 56 2e-06 UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein... 55 3e-06 UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06 UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A... 55 3e-06 UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06 UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon... 55 3e-06 UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente... 55 3e-06 UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu... 55 4e-06 UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol... 55 4e-06 UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ... 55 4e-06 UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 55 4e-06 UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2; Caeno... 55 4e-06 UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|... 55 4e-06 UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P... 54 5e-06 UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;... 54 5e-06 UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-... 54 7e-06 UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa... 54 7e-06 UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2; ... 54 7e-06 UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein... 54 9e-06 UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 54 9e-06 UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; ... 54 9e-06 UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ... 54 9e-06 UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependen... 53 1e-05 UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-... 53 1e-05 UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa... 53 1e-05 UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-... 53 2e-05 UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ... 53 2e-05 UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23; Cyanobacteri... 53 2e-05 UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 53 2e-05 UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger related-... 53 2e-05 UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Re... 53 2e-05 UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who... 53 2e-05 UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 2e-05 UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 2e-05 UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 2e-05 UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1; u... 52 2e-05 UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e... 52 2e-05 UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 3e-05 UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 3e-05 UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 3e-05 UniRef50_O83997 Cluster: Conserved hypothetical integral membran... 52 4e-05 UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 52 4e-05 UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro... 51 5e-05 UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; S... 51 5e-05 UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P... 51 5e-05 UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph... 51 5e-05 UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter therma... 51 7e-05 UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H... 51 7e-05 UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05 UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 9e-05 UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 9e-05 UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05 UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr... 50 9e-05 UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeb... 50 1e-04 UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol... 50 1e-04 UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 50 1e-04 UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum... 50 1e-04 UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091... 50 1e-04 UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute car... 50 2e-04 UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whol... 49 2e-04 UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 49 2e-04 UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-... 49 2e-04 UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1; Thermoc... 49 2e-04 UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A... 49 3e-04 UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomon... 48 4e-04 UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane pro... 48 4e-04 UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ... 48 5e-04 UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein, expre... 48 5e-04 UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ... 48 6e-04 UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip... 47 8e-04 UniRef50_A0VUH2 Cluster: Sodium/calcium exchanger membrane regio... 47 8e-04 UniRef50_A7THZ1 Cluster: Putative uncharacterized protein; n=1; ... 47 8e-04 UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome s... 47 0.001 UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno... 47 0.001 UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:... 47 0.001 UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces cere... 47 0.001 UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula... 46 0.001 UniRef50_A1G1U8 Cluster: Sodium/calcium exchanger membrane regio... 46 0.001 UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 46 0.002 UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein B14D6.... 46 0.002 UniRef50_A1CY62 Cluster: Sodium/calcium transporter, putative; n... 46 0.002 UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane regio... 46 0.003 UniRef50_Q75D63 Cluster: ABR160Cp; n=1; Eremothecium gossypii|Re... 46 0.003 UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei... 45 0.003 UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein;... 45 0.003 UniRef50_Q2GS93 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003 UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea... 45 0.003 UniRef50_Q31GA5 Cluster: Ca2+:cation antiporter (CaCA) family tr... 45 0.004 UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3... 44 0.006 UniRef50_A1SUD1 Cluster: Sodium/calcium exchanger membrane regio... 44 0.006 UniRef50_A5E210 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_A1Z7I2 Cluster: CG14743-PA; n=1; Drosophila melanogaste... 44 0.008 UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, wh... 44 0.008 UniRef50_A4FZ20 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; M... 44 0.008 UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exch... 44 0.010 UniRef50_A5FXK2 Cluster: Sodium/calcium exchanger membrane regio... 44 0.010 UniRef50_A6TJL1 Cluster: Sodium/calcium exchanger membrane regio... 42 0.023 UniRef50_A6CEY3 Cluster: Putative cation transporter; n=1; Planc... 42 0.023 UniRef50_A6C0C7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.023 UniRef50_A5UZB1 Cluster: Sodium/calcium exchanger membrane regio... 42 0.023 UniRef50_A1Z7I1 Cluster: CG14744-PA; n=2; Sophophora|Rep: CG1474... 42 0.023 UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coeloma... 42 0.041 UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane regio... 42 0.041 UniRef50_A7HH14 Cluster: Cation antiporter; n=1; Anaeromyxobacte... 42 0.041 UniRef50_A5E209 Cluster: Putative uncharacterized protein; n=1; ... 42 0.041 UniRef50_Q67MI8 Cluster: Putative sodium/calcium exchanger prote... 41 0.054 UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrah... 41 0.054 UniRef50_Q4TEE8 Cluster: Chromosome undetermined SCAF5461, whole... 40 0.095 UniRef50_A1DFV4 Cluster: Sodium/calcium transporter, putative; n... 40 0.095 UniRef50_A6UIS8 Cluster: Sodium/calcium exchanger membrane regio... 40 0.13 UniRef50_Q29QD0 Cluster: AT15857p; n=2; Drosophila melanogaster|... 40 0.13 UniRef50_Q12424 Cluster: Putative cation exchanger YDL206W precu... 40 0.13 UniRef50_A3TSR9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.17 UniRef50_A4X234 Cluster: Sodium/calcium exchanger membrane regio... 39 0.22 UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;... 39 0.22 UniRef50_Q9K8Y5 Cluster: Cation antiporter; n=1; Bacillus halodu... 39 0.29 UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane regio... 39 0.29 UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like p... 39 0.29 UniRef50_A1Z8H3 Cluster: CG13223-PA; n=2; Sophophora|Rep: CG1322... 39 0.29 UniRef50_A1CEE3 Cluster: Sodium/calcium transporter, putative; n... 39 0.29 UniRef50_Q391I5 Cluster: Sodium/calcium exchanger membrane regio... 38 0.38 UniRef50_A3X0Y4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.38 UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:... 38 0.50 UniRef50_Q6FWK5 Cluster: Similar to sp|P47144 Saccharomyces cere... 38 0.67 UniRef50_A7CDV0 Cluster: Sodium/calcium exchanger membrane regio... 37 0.88 UniRef50_A0ZFP5 Cluster: Cation transporter, putative; n=1; Nodu... 37 0.88 UniRef50_Q2QLY2 Cluster: Sodium/calcium exchanger protein, expre... 37 0.88 UniRef50_A2XD69 Cluster: Putative uncharacterized protein; n=1; ... 37 0.88 UniRef50_A0EBJ8 Cluster: Chromosome undetermined scaffold_88, wh... 37 0.88 UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, wh... 37 0.88 UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whol... 37 1.2 UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot... 37 1.2 UniRef50_Q6KI24 Cluster: Ca2+/Na+ antiporter; n=1; Mycoplasma mo... 36 1.5 UniRef50_Q0EYN3 Cluster: Ca2+:cation antiporter, CaCA family pro... 36 1.5 UniRef50_A0QYN1 Cluster: Sodium/calcium exchanger protein; n=1; ... 36 1.5 UniRef50_A0M0N5 Cluster: Sodium/calcium exchanger protein; n=3; ... 36 1.5 UniRef50_UPI000155D014 Cluster: PREDICTED: similar to G protein-... 36 2.0 UniRef50_Q6A563 Cluster: Sodium/calcium exchanger protein; n=3; ... 36 2.0 UniRef50_Q4P3S5 Cluster: Putative uncharacterized protein; n=1; ... 36 2.0 UniRef50_A3VNK6 Cluster: Cation antiporter; n=5; Bacteria|Rep: C... 35 3.6 UniRef50_A1VRK4 Cluster: Sodium/calcium exchanger membrane regio... 35 3.6 UniRef50_Q0DZ55 Cluster: Os02g0644900 protein; n=3; Oryza sativa... 35 3.6 UniRef50_Q5A016 Cluster: Putative uncharacterized protein; n=1; ... 35 3.6 UniRef50_Q2UMT2 Cluster: Ca2+/H+ antiporter VCX1 and related pro... 35 3.6 UniRef50_A7TNF1 Cluster: Putative uncharacterized protein; n=1; ... 35 3.6 UniRef50_UPI00015BD6AB Cluster: UPI00015BD6AB related cluster; n... 35 4.7 UniRef50_Q9KXP3 Cluster: Putative integral membrane protein; n=3... 35 4.7 UniRef50_Q47GX6 Cluster: Putative signal transduction protein; n... 35 4.7 UniRef50_Q6CIX5 Cluster: Similarities with sgd|S0002286 Saccharo... 35 4.7 UniRef50_A7ECE3 Cluster: Putative uncharacterized protein; n=1; ... 35 4.7 UniRef50_A5DR29 Cluster: Putative uncharacterized protein; n=1; ... 35 4.7 UniRef50_A4RDF2 Cluster: Putative uncharacterized protein; n=1; ... 35 4.7 UniRef50_A0DA69 Cluster: Chromosome undetermined scaffold_43, wh... 34 6.2 UniRef50_A5E199 Cluster: Putative uncharacterized protein; n=1; ... 34 6.2 UniRef50_A5UZC9 Cluster: Glycosyl transferase, family 51 precurs... 34 8.2 >UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=3; Endopterygota|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 542 Score = 423 bits (1042), Expect = e-117 Identities = 208/379 (54%), Positives = 257/379 (67%), Gaps = 25/379 (6%) Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122 RNCTPAAI EFPSDG TR +R+HG+I +H +A YCF LL VC+DYFVPAIE++C++L Sbjct: 95 RNCTPAAIFEFPSDGFTREERKHGWITVHLLIACYCFWLLAIVCDDYFVPAIELMCKKLQ 154 Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 + DIAGATFMAAASSSPELFINCVGTF+T+GD+GVGAVVGSAVFN+LAVPA C LF G Sbjct: 155 VKEDIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQ 214 Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL-----EKIN-- 235 V++L WW VTRD MMY LI L D K+ W+EA +LV Y YI + IN Sbjct: 215 VVQLRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAMICNDSINRF 274 Query: 236 ------------PLDASQRMTP--RSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGD 281 P + P + QN +G + + GS+ S S F Sbjct: 275 MSRTFRRKSCIRPYTEVTEIAPLLSNGQNNGASKGSQNGQNGHGCGSEASEDSFQDFELA 334 Query: 282 KISFWKK----LFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWII 337 + ++ ++ WPI +LWATIPDCR + LTF +CI WIG SY VA++I Sbjct: 335 STPWSRRDENTFAYICRWPITFLLWATIPDCRRYPKLRILTFFVCIFWIGITSYFVAFLI 394 Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 TVVGDT+++PDS+ GLT LAAGTS+PEAVSS++VT QGHG MGISNSIGSNTFDILLCLG Sbjct: 395 TVVGDTMDIPDSVMGLTFLAAGTSVPEAVSSIIVTNQGHGEMGISNSIGSNTFDILLCLG 454 Query: 398 LPWLVKSLFYPSTPENHWV 416 LPWL+K+L +P+ P +WV Sbjct: 455 LPWLIKALAFPAIPGENWV 473 >UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute carrier family 24, member 5; n=1; Apis mellifera|Rep: PREDICTED: similar to solute carrier family 24, member 5 - Apis mellifera Length = 439 Score = 418 bits (1029), Expect = e-115 Identities = 199/356 (55%), Positives = 253/356 (71%), Gaps = 9/356 (2%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NCTP AI EFPSDGLTR QRQ GFIL+H +A+Y FLLL VC+D+FVP+I+ IC+++N+ Sbjct: 23 NCTPPAIKEFPSDGLTREQRQLGFILIHFVIAIYMFLLLAIVCDDFFVPSIKKICDKINV 82 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 + D+AGAT MA A+SSPELFIN VGTF+TEGDLGVG +VGSAVFN+LAVPACC LFA + Sbjct: 83 SEDVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQI 142 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRM 243 + L+ W VTRD + Y LILTL D +I W+EAL+LVL Y YIL + D + Sbjct: 143 LNLEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYIL--VMCFDRNIHQ 200 Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWA 303 + V ++ + S++ ++ ++P K ++++W++TWPI +L Sbjct: 201 FIQYVTR--TKKKYKNLSEKTPLFSNVEIVNMTNWPKSKC---ERIWWLITWPINFVLLI 255 Query: 304 TIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTS 361 TIPDCR S YPLTFIMCI WI S SY+V W+ITV+GDT +PDSI GLT LAAG S Sbjct: 256 TIPDCRRNTLKSWYPLTFIMCIIWIASTSYIVGWVITVIGDTFRIPDSIMGLTFLAAGMS 315 Query: 362 LPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417 +PEAVSSV+V QGHG MGISNSIGSN FD+LLCLGLPW +K+ + P NH+VT Sbjct: 316 VPEAVSSVIVANQGHGAMGISNSIGSNVFDVLLCLGLPWFLKAALFSKEPGNHYVT 371 >UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute carrier family 24, member 5; n=1; Tribolium castaneum|Rep: PREDICTED: similar to solute carrier family 24, member 5 - Tribolium castaneum Length = 488 Score = 295 bits (723), Expect = 2e-78 Identities = 144/363 (39%), Positives = 224/363 (61%), Gaps = 32/363 (8%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 +FPS T Q + G I+L + +YCF LL +C++YF+P +E ICE LN++ D+A AT Sbjct: 51 DFPSM-FTETQVEKGGIILVFCIGIYCFTLLAIICDNYFLPCVEKICEALNLSHDVAAAT 109 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FM+ A+S+PELF+N +GTF+TE D+G+G VVGS++FN L V + +L A ++L WW + Sbjct: 110 FMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAASTPVQLHWWPI 169 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY---ILEKINPLDASQRMTPRSV 248 +RD ++Y L+ D IYW+E L+L L+Y Y + + + + R+ R Sbjct: 170 SRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVRISNFVLRLIKRGN 229 Query: 249 QNGDLERGIEMTRRHDS--------------------------TGSDISTSSVWSFPGDK 282 + D E+G T R S T ++ + S++ P K Sbjct: 230 KVSDCEKGAAATPRRMSIAVVSSYGSYAEEQINKYTETKNIAETATEEESFSLFRMP--K 287 Query: 283 ISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGD 342 S WKK F+ +WPI+ IL+ T+PD ++P+TFI+CI WIGS SY+V+W+I ++G+ Sbjct: 288 GSIWKKAFFYYSWPIKFILFCTVPDPMRYPKLFPVTFILCIFWIGSNSYIVSWMIAIIGN 347 Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 +PD++ GLT LAAG LPEA+S +++++G G+MG+SNS+G+NT +ILL LG+PW + Sbjct: 348 MFKIPDAVLGLTFLAAGGCLPEAISITIMSRRGEGSMGVSNSLGANTMNILLSLGMPWFL 407 Query: 403 KSL 405 K++ Sbjct: 408 KTI 410 >UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 429 Score = 278 bits (682), Expect = 2e-73 Identities = 137/364 (37%), Positives = 219/364 (60%), Gaps = 19/364 (5%) Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124 C P I EFP D LT+ QR +G ++LH +L+ F L VCED+FV ++ I L + Sbjct: 1 CRPPNIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLK 60 Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 D+AGATFMA SS+P LFI + F TEGD+G+G +VGS +FN L + A CA+ +G + Sbjct: 61 PDVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTL 120 Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL-----EKINPL-- 237 +L + ++RD +Y L++++ D+K+YW+E L+ V++Y YI+ +++ L Sbjct: 121 QLACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMYFNDQVEGLCK 180 Query: 238 DASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSF---PGDKI----SFWKKLF 290 +++ + V+ +G++ +S +++ S W F P ++ + Sbjct: 181 TVKKKLKKKKVKPEGEGQGVDEDGGEESE-DELNKSEDWGFHDTPRTRLKPPEGACARAL 239 Query: 291 WVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348 WV T P L+ + TIPDCR + Y +TF + + W+ +SY + W++ ++G T +P+ Sbjct: 240 WVFTLPSILVFYVTIPDCRKKTWRKFYLVTFTVAVIWMAVLSYFLVWMVAIIGYTYTIPE 299 Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF-Y 407 + G+T LAAG+SLP+A++S++V KQG G M +SN IGSN FD +LCLG+PWL+KS F Sbjct: 300 CVMGMTFLAAGSSLPDAIASLVVAKQGSGDMAVSNCIGSNVFD-MLCLGIPWLIKSAFLQ 358 Query: 408 PSTP 411 P P Sbjct: 359 PGKP 362 >UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo sapiens (Human) Length = 500 Score = 268 bits (658), Expect = 1e-70 Identities = 139/380 (36%), Positives = 219/380 (57%), Gaps = 39/380 (10%) Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124 C + EFP TR +R+ G I+++ + +Y F+ + VC++YF+P++EII E L ++ Sbjct: 46 CVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLS 105 Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 D+AG TFMAA SS+PEL +G F+T+GD+G+ ++GSA++N+L + A C L + V Sbjct: 106 QDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVS 165 Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTF-------------YIL 231 L W + RDC Y ++ + D+++YW+E LL+L+Y YI+ Sbjct: 166 TLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYII 225 Query: 232 EKINPLDAS-QRMTPRSVQN---GDLERGIEMTRRHDSTGSDI---------------ST 272 +K +P A + RS Q G + G RR T S I Sbjct: 226 KKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSISLHGL 285 Query: 273 SSVWSFPGDKISF----WKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWI 326 S V P + K++FWVL+ PI +L+ T PDCR + + + +TF M WI Sbjct: 286 SQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWI 345 Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386 + +Y++ W++T+ G+TL +PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +G Sbjct: 346 SAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVG 405 Query: 387 SNTFDILLCLGLPWLVKSLF 406 SN FD +LCLG+PW +K+ F Sbjct: 406 SNVFD-MLCLGIPWFIKTAF 424 >UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative - Nasonia vitripennis Length = 561 Score = 268 bits (656), Expect = 2e-70 Identities = 130/244 (53%), Positives = 168/244 (68%), Gaps = 13/244 (5%) Query: 4 RTRQYERKHRVATIVRVVLFFGIPIVYMV-----------AKSIASNQVIVFDEPEAFSS 52 R R+ R+ R +R+ L IP +Y++ A+S+A++ D SS Sbjct: 22 RRRRRRRRRRRRRDIRLALVLAIPSIYLLLASLASLTGFAAQSVATSSGFTGDASFVRSS 81 Query: 53 RHLLGI--VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYF 110 R LL + V I+ NCTP +I EFPSDGLTR+QRQHGFI++H +A Y F LL VC+D+F Sbjct: 82 RKLLALNLVPIQENCTPPSIKEFPSDGLTRYQRQHGFIVIHVIIACYAFFLLAIVCDDFF 141 Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 VP+I IC+++ ++ D+AGATFMAAASSSPELFIN VGTFVTEGDLGVG +VGSAVFN+L Sbjct: 142 VPSIVKICDKIGMSKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNIL 201 Query: 171 AVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 AVPACC LFA V++LDWW ++RD + Y LI TL D +I W+EA +LVL Y FYI Sbjct: 202 AVPACCGLFASQVLDLDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYI 261 Query: 231 LEKI 234 L + Sbjct: 262 LAMV 265 Score = 201 bits (491), Expect = 2e-50 Identities = 94/170 (55%), Positives = 118/170 (69%), Gaps = 7/170 (4%) Query: 249 QNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDC 308 QNGD +++ S +I + W D + W++ +WV TWPI IL TIPDC Sbjct: 328 QNGDCNGVMDVESLESSEELEIVNMTEWP---DNV--WERCWWVFTWPINAILLITIPDC 382 Query: 309 RHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366 R + YPLTFIMCI WI +SY+V W IT++GDTL +PDS+ GLT LAAG S+PEAV Sbjct: 383 RRPSLRNWYPLTFIMCIVWIALMSYIVGWDITIIGDTLMIPDSVMGLTFLAAGMSVPEAV 442 Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416 SSV+VT QGHGTMGISNSIGSN FD+LLCLGLPW +K+ F+P+ H+V Sbjct: 443 SSVIVTNQGHGTMGISNSIGSNVFDVLLCLGLPWFIKASFFPTAAGEHFV 492 Score = 40.7 bits (91), Expect = 0.072 Identities = 22/57 (38%), Positives = 31/57 (54%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 I II + L I + G TF+AA S PE + + T G +G+ +GS VF+VL Sbjct: 413 ITIIGDTLMIPDSVMGLTFLAAGMSVPEAVSSVIVTNQGHGTMGISNSIGSNVFDVL 469 Score = 37.9 bits (84), Expect = 0.50 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL--- 393 I + D + + + G T +AA +S PE +++ T G +G+ +GS F+IL Sbjct: 145 IVKICDKIGMSKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVP 204 Query: 394 LCLGL 398 C GL Sbjct: 205 ACCGL 209 >UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).; n=1; Danio rerio|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3). - Danio rerio Length = 419 Score = 263 bits (644), Expect = 7e-69 Identities = 134/342 (39%), Positives = 207/342 (60%), Gaps = 32/342 (9%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155 +Y F L VC+DYFVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T+GD Sbjct: 1 MYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 60 Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215 +GVG +VGSAVFN+L + C +F + L W++ RD Y LI+ + D+K+ Sbjct: 61 VGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 120 Query: 216 WHEALLLVLMYTFYIL-----EKINPLDASQRMTPRSVQNG-----DLERGIEMT----- 260 W E+L+L+++Y YIL ++ ++ P ++ NG D++ G + T Sbjct: 121 WWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDIDDGCDATVVLLK 180 Query: 261 --------RRHDSTGSDISTSSVWSFPG--DKISFWK-----KLFWVLTWPIRLILWATI 305 + + +S S K+ F+K KL W+L WP+ ++L+ T+ Sbjct: 181 KGNNSIPRSKKGNITVHVSYESCHKVNDLFKKLLFFKSGGINKLKWLLAWPLSMLLFFTV 240 Query: 306 PDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363 P+ + Y ++FI WI SY++ W++TV+G T+ +PD I G+T LAAGTS+P Sbjct: 241 PNSANPRWERWYMVSFISSTIWIAFFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVP 300 Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + ++S++V +QG G M ISNSIGSN FDIL+ LGLPW +++L Sbjct: 301 DCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTL 342 >UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster (Fruit fly) Length = 353 Score = 255 bits (625), Expect = 1e-66 Identities = 124/284 (43%), Positives = 180/284 (63%), Gaps = 8/284 (2%) Query: 126 DIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 D+AGATF+AA++S+PELF+N VGTFVT GD+G+G +VGS+VFN+L + C +F + Sbjct: 4 DVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQPT-K 62 Query: 186 LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTP 245 LDWW VTRD Y L L D + W+EA L+L+Y Y+++ + Sbjct: 63 LDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRR 122 Query: 246 RSVQNGDLERGIE--MTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWA 303 + ++ + E E MTR + V + P + +F++ +W + +P L+L Sbjct: 123 KKNEHAESELLDEDPMTREEEPLKG--FRDHVCAKPKTEYNFYQWTWWAIKYPAELMLAC 180 Query: 304 TIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363 T+P R SI+ L+ I I WI +SYL+ W +T++G LN+PD+I GLT+LAAGTS+P Sbjct: 181 TVPSAR---SIFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVP 237 Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 E SS +V+K+G+G+M I N+IGSNTFDIL+CLGLPWL+K L Y Sbjct: 238 EVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKILIY 281 >UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG2893-PB.3 - Tribolium castaneum Length = 480 Score = 215 bits (525), Expect = 2e-54 Identities = 95/172 (55%), Positives = 128/172 (74%), Gaps = 4/172 (2%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NCTP AI +FP D T +RQ G +++H ++LY F+ L VC+ +FVPA+E IC LN+ Sbjct: 4 NCTPPAIDDFPRDFFTEKERQDGAVVVHVVVSLYLFVALAVVCDKFFVPAVEKICHALNM 63 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG-- 181 ++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG Sbjct: 64 SADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGLC 123 Query: 182 --AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 V+ LDWW +TRDC+ Y LI + D+++ W+EAL LVL+YT YIL Sbjct: 124 GVKVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYIL 175 Score = 208 bits (508), Expect = 2e-52 Identities = 92/145 (63%), Positives = 112/145 (77%), Gaps = 3/145 (2%) Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331 S+W +P + F + WV+TWPI LI TIPDC +PLTFIMCI WIGS+SY Sbjct: 268 SLWKWPAGRSKF-TQFTWVITWPIHLIFLFTIPDCEKPRFKKWFPLTFIMCIIWIGSLSY 326 Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 +VAW+IT++GDTL +PDS+ G+T LAAGTS+PEAVSSV+V KQGHG+MGISNSIGSNTFD Sbjct: 327 VVAWMITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHGSMGISNSIGSNTFD 386 Query: 392 ILLCLGLPWLVKSLFYPSTPENHWV 416 ILLCLGLPW +K+ F P+ HWV Sbjct: 387 ILLCLGLPWFIKATFMPTIAGKHWV 411 Score = 41.5 bits (93), Expect = 0.041 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 96 LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 + C + +GS+ Y V I II + L I + G TF+AA +S PE + + G Sbjct: 315 IMCIIWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHG 372 Query: 155 DLGVGAVVGSAVFNVL 170 +G+ +GS F++L Sbjct: 373 SMGISNSIGSNTFDIL 388 Score = 39.1 bits (87), Expect = 0.22 Identities = 19/50 (38%), Positives = 28/50 (56%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 LN+ + G T +AA TS PE +V+ T G +G+ +GS F+IL Sbjct: 61 LNMSADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 110 >UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2; Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX - Ostreococcus tauri Length = 443 Score = 214 bits (523), Expect = 3e-54 Identities = 124/337 (36%), Positives = 189/337 (56%), Gaps = 20/337 (5%) Query: 84 QHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF 143 ++G +L+ LY FL + VC+DYFV ++E IC++L ++ D+AGATFMAA SS+PELF Sbjct: 35 RNGGWVLYVVGILYMFLGIAIVCDDYFVSSLEKICDKLGLSEDVAGATFMAAGSSAPELF 94 Query: 144 INCVGTFVTEG--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXX 201 + + + ++G+ A+VGSAVFN+L + L AG ++LDW VTRDCM Y Sbjct: 95 SSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCAGCSLDLDWRPVTRDCMFYAMA 154 Query: 202 XXXLILTLLDDKIYWHEALLLVLMYTFYIL-EKINPL------DASQR----MTPRSVQN 250 ++L D +I W+E L+ VL+Y Y+L N + AS+R M P Sbjct: 155 VLTVLLIFYDGRITWYEGLICVLLYATYVLCMCYNDVLMRWMGGASKRPKQLMVPEPTPT 214 Query: 251 --GDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDC 308 L R + ++ SF S L V++ P R +IP+C Sbjct: 215 TVPALRRADTRRQSRRPMREEVVEDEDKSFEWPDSSLGIPLH-VISLPWRFAFHFSIPNC 273 Query: 309 --RHRHSIYPLTFIMCITWIGSVSY-LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA 365 + R + + +TF+ I+WI +SY +V+W VG + +P+ + G ++AAGTS+P+A Sbjct: 274 ALKQRENWFAMTFLASISWISLISYCMVSWAAR-VGCVIGIPEVVMGTLVVAAGTSIPDA 332 Query: 366 VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 + S+ V K G G M ++N++GSN FDI L LGLPWL+ Sbjct: 333 LGSIAVAKAGEGDMAVANAVGSNIFDIWLGLGLPWLI 369 >UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster (Fruit fly) Length = 542 Score = 210 bits (514), Expect = 4e-53 Identities = 91/167 (54%), Positives = 123/167 (73%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NCT AI +FP D + QRQ G ++LH +LY F+ L VC++YFVPA+E IC LN+ Sbjct: 21 NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNM 80 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 ++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG Sbjct: 81 SNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMT 140 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 I LDWW +TRD + Y LI + D+++ W+EAL+LV +Y Y+ Sbjct: 141 IPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYL 187 Score = 201 bits (491), Expect = 2e-50 Identities = 88/145 (60%), Positives = 116/145 (80%), Gaps = 3/145 (2%) Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRH--RHSIYPLTFIMCITWIGSVSY 331 S+ S+P DK F + W++ WPI L+ IPDC+ + I+PLTFIMCI WIGS+SY Sbjct: 329 SLLSYPKDKSCF-AQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSY 387 Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 +VAW+IT++GDTL +PDS+ G+T LAAGTS+PEAVSSV+V K+GHG+MGI NSIGSNTFD Sbjct: 388 VVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFD 447 Query: 392 ILLCLGLPWLVKSLFYPSTPENHWV 416 ILLCLG+PWL+K++F+P P ++V Sbjct: 448 ILLCLGVPWLIKAVFFPIQPGQNYV 472 Score = 40.3 bits (90), Expect = 0.095 Identities = 19/50 (38%), Positives = 29/50 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 LN+ + + G T +AA TS PE +V+ T G +G+ +GS F+IL Sbjct: 78 LNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 127 Score = 39.5 bits (88), Expect = 0.17 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 96 LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 + C + +GS+ Y V I II + L I + G TF+AA +S PE + + G Sbjct: 376 IMCIVWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHG 433 Query: 155 DLGVGAVVGSAVFNVL 170 +G+ +GS F++L Sbjct: 434 SMGICNSIGSNTFDIL 449 >UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae str. PEST Length = 386 Score = 207 bits (505), Expect = 5e-52 Identities = 113/335 (33%), Positives = 179/335 (53%), Gaps = 31/335 (9%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 + P D T QR G I+LH A+Y F+LL VC +YF+P++E +CE L ++ D+A AT Sbjct: 5 DLPPDLFTEEQRLQGAIVLHFLAAIYFFMLLAYVCSEYFLPSVECLCEDLKLSQDVAAAT 64 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMA A+S PE F N + T D +G VG+ + ++L A G + ++ Sbjct: 65 FMATATSMPEFFTNTISTLAV--DSDIG--VGTIMGSMLFNTLGVAALVGLLTKMP---- 116 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTP-RSVQN 250 D +DDK+ + + +L + + K+ P S P V Sbjct: 117 -ED-------------GTIDDKVP-KKYNIAILGHAINGVLKLPPSSESSTSAPIEPVDP 161 Query: 251 GDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRH 310 +E + + S + P + W+ + W+ TWP R +++ TIPD Sbjct: 162 SCSNSSVESVK-------SVKWSELTQLPEASFAGWRTIMWIFTWPYRFVVFLTIPDPLR 214 Query: 311 RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL 370 +YPLTF+ CI WIG +YLV W+I+V+G+T +PD++ G+T LA G +PEA S++ Sbjct: 215 FRKLYPLTFVCCIGWIGVSAYLVFWMISVIGNTFGIPDTVMGMTFLAFGGCMPEAASAIT 274 Query: 371 VTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + ++G+G MG+SNS+G+NT IL LGLPW ++++ Sbjct: 275 LIRRGNGAMGVSNSLGANTLAILFSLGLPWFIRTM 309 >UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-dependent Na/Ca exchanger NCKX3; n=2; Deuterostomia|Rep: PREDICTED: similar to potassium-dependent Na/Ca exchanger NCKX3 - Strongylocentrotus purpuratus Length = 570 Score = 205 bits (500), Expect = 2e-51 Identities = 91/192 (47%), Positives = 129/192 (67%), Gaps = 4/192 (2%) Query: 57 GIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEI 116 G+ E+E NCTP+ I EFP D T QR G + H A+Y F+ L VC+DYFV ++E Sbjct: 68 GVHEVEMNCTPSTIEEFPGDLFTEEQRAKGAFITHAICAVYMFIALAIVCDDYFVSSLEK 127 Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ICE L++ D+AGATFMAA SS+PELF + +G F+ +GD+GVG +VGSAVFN+L + C Sbjct: 128 ICENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLC 187 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL----E 232 LFAG V+ L WW + RD ++Y L+L + D I W+EAL+++LMY Y++ + Sbjct: 188 GLFAGQVVHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIMCFD 247 Query: 233 KINPLDASQRMT 244 I PL+A++ +T Sbjct: 248 IITPLNATEDIT 259 Score = 139 bits (336), Expect = 1e-31 Identities = 59/120 (49%), Positives = 88/120 (73%), Gaps = 2/120 (1%) Query: 289 LFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNV 346 L W++T PI ++L+ TIPDCR + Y +TF + + WI SY++ W++ +G TL++ Sbjct: 375 LKWIVTLPICILLFFTIPDCRRKRFDRWYMVTFFISVAWIAIFSYVMVWMVAYIGHTLHI 434 Query: 347 PDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406 PD+I G+T LAAGTS+P+A++S+LV ++G G M +SNSIGSN FDIL+ L LPW +K+ F Sbjct: 435 PDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNVFDILIGLALPWFIKTAF 494 Score = 46.0 bits (104), Expect = 0.002 Identities = 20/57 (35%), Positives = 35/57 (61%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL+ +GL Sbjct: 130 ENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGL 186 Score = 35.5 bits (78), Expect = 2.7 Identities = 19/57 (33%), Positives = 30/57 (52%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 + I L+I I G TF+AA +S P+ + + GD+ V +GS VF++L Sbjct: 425 VAYIGHTLHIPDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNVFDIL 481 >UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar to Na-Ca exchanger 5 - Apis mellifera Length = 489 Score = 202 bits (493), Expect = 1e-50 Identities = 87/170 (51%), Positives = 121/170 (71%) Query: 62 ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121 ++ CT +I +FP D T QR+HG ++LH FL LYCFLL VC DY +PA++ IC L Sbjct: 23 DKKCTDRSIHDFPEDLFTYEQRRHGAVILHAFLGLYCFLLTAFVCHDYLLPAVDRICISL 82 Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181 NI++D+AGATF+A ASS PELF+N +GTF+TE DLG G VVGSAVF+ A PAC AL Sbjct: 83 NISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTF 142 Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 I L+W ++RDC+MY L++ + D KI W+EA++L++++ FY++ Sbjct: 143 YAISLEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLI 192 Score = 148 bits (358), Expect = 3e-34 Identities = 66/122 (54%), Positives = 91/122 (74%), Gaps = 4/122 (3%) Query: 287 KKLFWVLTWPIRLILWATIPDC---RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDT 343 +K +++ WP++ +L+ TIPD R +H YPLTFIMCI WIG SYLV+W+ TV+GD Sbjct: 294 EKCWFMFGWPLKFLLFITIPDPKIERLKHW-YPLTFIMCIIWIGISSYLVSWMTTVIGDI 352 Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + +PDSI GLT LAAG ++PE S V++ +QG G M +SN++G+N DILLCLGLPW++K Sbjct: 353 IGIPDSIMGLTFLAAGGNMPEVASIVILARQGDGNMAMSNTLGANILDILLCLGLPWMIK 412 Query: 404 SL 405 L Sbjct: 413 CL 414 Score = 33.9 bits (74), Expect = 8.2 Identities = 16/49 (32%), Positives = 24/49 (48%) Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 +LN+ + G T LA +S PE +V+ T +G +GS FD Sbjct: 81 SLNISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFD 129 >UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 569 Score = 195 bits (475), Expect = 2e-48 Identities = 89/170 (52%), Positives = 119/170 (70%) Query: 62 ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121 E+NCT AI EFP D T QR G +LLH F ALY FL L VC+DYFV ++E ICE+L Sbjct: 58 EKNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEKL 117 Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181 +++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VGSAVFN+L + C +FAG Sbjct: 118 HLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAG 177 Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 V+ L ++V RD Y LI+ + DD+I W E+L+L++MY YI+ Sbjct: 178 QVVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYII 227 Score = 129 bits (311), Expect = 2e-28 Identities = 53/115 (46%), Positives = 85/115 (73%), Gaps = 2/115 (1%) Query: 293 LTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSI 350 ++WPI L+L+ TIP+C + + L+F + WI + SY++ W++T+VG TL +PD I Sbjct: 375 ISWPISLLLYFTIPNCAKKRWECCFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVI 434 Query: 351 TGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++ Sbjct: 435 MGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGIQTM 489 Score = 46.0 bits (104), Expect = 0.002 Identities = 19/57 (33%), Positives = 35/57 (61%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + L++ + + G T +AAG+S PE +S++ HG +G+ +GS F+IL +G+ Sbjct: 115 EKLHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGV 171 Score = 37.1 bits (82), Expect = 0.88 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 92 CFLALYCFLLLGSVCEDYF-VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTF 150 CF+ + + Y V + I+ L I I G TF+AA +S P+ + + Sbjct: 398 CFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVAR 457 Query: 151 VTEGDLGVGAVVGSAVFNVL 170 GD+ V +GS VF++L Sbjct: 458 QGLGDMAVSNTIGSNVFDIL 477 >UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=1; Aedes aegypti|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 492 Score = 194 bits (474), Expect = 3e-48 Identities = 85/132 (64%), Positives = 109/132 (82%), Gaps = 2/132 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDC-RHRHSI-YPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 ++ W++TWPI L+ TIP+C + R+ +PLTFIMCI WIGS+SY+VAW+IT++GDTL Sbjct: 292 RQFSWIITWPIYLLFVFTIPNCAKPRYKKWFPLTFIMCIVWIGSLSYVVAWMITIIGDTL 351 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 +PDS+ G+T LAAGTS+PEAVSSV+V KQG+G+MGISNSIGSNTFDILLCLGLPW +K+ Sbjct: 352 KIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYGSMGISNSIGSNTFDILLCLGLPWFIKA 411 Query: 405 LFYPSTPENHWV 416 F P +HWV Sbjct: 412 AFSPIEKGHHWV 423 Score = 155 bits (375), Expect = 3e-36 Identities = 64/108 (59%), Positives = 87/108 (80%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 +++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG Sbjct: 1 MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60 Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 V+ LDWW +TRDC+ Y LI + D+++ W+EAL+LVL+Y YI Sbjct: 61 VVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYI 108 Score = 40.3 bits (90), Expect = 0.095 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 96 LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 + C + +GS+ Y V I II + L I + G TF+AA +S PE + + G Sbjct: 327 IMCIVWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYG 384 Query: 155 DLGVGAVVGSAVFNVL 170 +G+ +GS F++L Sbjct: 385 SMGISNSIGSNTFDIL 400 Score = 36.3 bits (80), Expect = 1.5 Identities = 17/46 (36%), Positives = 26/46 (56%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 + + G T +AA TS PE +V+ T G +G+ +GS F+IL Sbjct: 3 NDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 48 >UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55; Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo sapiens (Human) Length = 644 Score = 194 bits (474), Expect = 3e-48 Identities = 85/169 (50%), Positives = 119/169 (70%) Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122 +NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+ Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144 Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 ++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204 Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+ Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253 Score = 132 bits (318), Expect = 2e-29 Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%) Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348 W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509 Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566 Score = 42.7 bits (96), Expect = 0.018 Identities = 19/57 (33%), Positives = 34/57 (59%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+ Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197 Score = 36.7 bits (81), Expect = 1.2 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 + II L I I G TF+AA +S P+ + + GD+ V +GS VF++L Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554 >UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 490 Score = 194 bits (472), Expect = 5e-48 Identities = 85/168 (50%), Positives = 117/168 (69%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NCTP AILEFP D T+ QRQ G ++L+ ++LY F + VC+DYFVP +EIIC+RL + Sbjct: 1 NCTPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGL 60 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 +D+AGATFMA SS+PELF + +G F+T+GD+GVG ++GSAVFNVL V C + AG V Sbjct: 61 QTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTV 120 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 + L WW + RD + Y L+L L+D+ + W EA +V Y+ Y+L Sbjct: 121 LYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLL 168 Score = 136 bits (330), Expect = 8e-31 Identities = 61/138 (44%), Positives = 95/138 (68%), Gaps = 5/138 (3%) Query: 269 DISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWI 326 D++ S +S P + W ++ WVL PI L + TIPD + L+FI+CI WI Sbjct: 276 DLTLGSPFSPPEN---VWPRICWVLGLPINLSFFLTIPDVKKPSCEKWVVLSFIICIVWI 332 Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386 G SY++ W++TV+G T +PDS+ GL+++A G+S+P+ +SS+ V ++G G M +S+++G Sbjct: 333 GVTSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVG 392 Query: 387 SNTFDILLCLGLPWLVKS 404 SN FDILLCLG+PWL+K+ Sbjct: 393 SNVFDILLCLGIPWLIKT 410 Score = 41.9 bits (94), Expect = 0.031 Identities = 18/62 (29%), Positives = 34/62 (54%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + ++ D L + + G T +A G+S PE +SV+ G +G+ +GS F++L + Sbjct: 51 LEIICDRLGLQTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVI 110 Query: 397 GL 398 G+ Sbjct: 111 GV 112 >UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to RE34149p - Nasonia vitripennis Length = 542 Score = 186 bits (454), Expect = 7e-46 Identities = 85/166 (51%), Positives = 111/166 (66%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NC +I +FP D T QRQ G IL H F LYCFLL VC DY +PA++ IC L I Sbjct: 55 NCLAHSIEDFPEDLFTLQQRQQGAILFHIFFGLYCFLLTAFVCNDYLLPALDCICADLRI 114 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 ++D+AGATF+A AS PELF+N VGTF+TE DLGVGAVVG AVFN A PA ALFA Sbjct: 115 SADVAGATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAVFNTFATPAVGALFAAKG 174 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 I+L W ++RDC++Y L+L + D + W+E+++L+ ++ Y Sbjct: 175 IQLQWHILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLFASY 220 Score = 164 bits (398), Expect = 5e-39 Identities = 79/160 (49%), Positives = 108/160 (67%), Gaps = 9/160 (5%) Query: 254 ERGIEMTRRHDSTGSDISTSSVWSFPGDKISFW------KKLFWVL-TWPIRLILWATIP 306 E GI+ R T S +T+S D I W + FW L TWPI+LIL+ TIP Sbjct: 309 EPGIKTISRASETTSAPTTTSKSCNLSDTIFMWPSKSSTSEKFWFLFTWPIKLILFVTIP 368 Query: 307 DCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364 D R++ YP+TFIMC+ WI SY+V+W+ TVVGDT+ +PDS+ G+T L+AG +LPE Sbjct: 369 DSRYKRLRKFYPITFIMCVMWIAVSSYMVSWMTTVVGDTVGIPDSVMGITFLSAGGNLPE 428 Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 VS V++++QGHG M +SN+IG+NT DILLCL LPW +++ Sbjct: 429 MVSIVILSRQGHGDMAMSNTIGANTLDILLCLSLPWAIRN 468 >UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger - Tursiops truncatus (Atlantic bottle-nosed dolphin) Length = 1014 Score = 169 bits (411), Expect = 1e-40 Identities = 85/211 (40%), Positives = 126/211 (59%), Gaps = 10/211 (4%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + +R+ G+++LH F LY F+ L VC++YFVPA+ +I ++L I+ D+AGAT Sbjct: 435 EYPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 494 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 495 FMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 554 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI--------LEKINPLDASQRM 243 RD Y LIL LD I W E+LLL+L Y Y+ LE S+R Sbjct: 555 FRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELWVKKQLSRRP 614 Query: 244 TPRSVQNGDLERG--IEMTRRHDSTGSDIST 272 P+ + GDL +G E + T +++ T Sbjct: 615 VPKVMALGDLSKGDVAEAESTGERTDNEVKT 645 Score = 112 bits (269), Expect = 2e-23 Identities = 52/120 (43%), Positives = 78/120 (65%), Gaps = 2/120 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW T+PD R + + +TF+ I WI SYL+ W VG+T+ Sbjct: 822 KQAIYLFLLPIVFPLWLTVPDVRRLEARKFFVITFLGSIMWIAMFSYLMVWWAHQVGETI 881 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPW++ S Sbjct: 882 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWMLFS 941 Score = 47.2 bits (107), Expect = 8e-04 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ + ++ I Y V + V+ D L + + + G T +AAG S PE +S++ Sbjct: 455 IFGMLYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGIF 513 Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397 H +GI +GS F+IL +G Sbjct: 514 ISHSNVGIGTIVGSAVFNILFVIG 537 Score = 38.3 bits (85), Expect = 0.38 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 879 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWM 938 Query: 178 LFA 180 LF+ Sbjct: 939 LFS 941 >UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7; Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) - Drosophila melanogaster (Fruit fly) Length = 888 Score = 169 bits (410), Expect = 2e-40 Identities = 83/194 (42%), Positives = 118/194 (60%), Gaps = 4/194 (2%) Query: 38 SNQVIVFDEPEAFSSRHLLGIVEIER-NCTPAAILEFPSDGLTRFQRQHGFILLHCFLAL 96 SN V DE A + R GI + N T FP D T+ Q ++G ++LH + Sbjct: 285 SNAVPGSDEDNAGNQR---GINDTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVI 341 Query: 97 YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156 Y F+ L VC+++FVP++++I E+L I D+AGATFMAA S+PELF + +G FV+ D+ Sbjct: 342 YMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDV 401 Query: 157 GVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216 G+G +VGSAVFN+L V CALF+ V+ L WW + RDC Y LI D++I+W Sbjct: 402 GIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFW 461 Query: 217 HEALLLVLMYTFYI 230 EAL+L +Y Y+ Sbjct: 462 WEALILFTIYIGYV 475 Score = 124 bits (300), Expect = 3e-27 Identities = 55/128 (42%), Positives = 83/128 (64%), Gaps = 2/128 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+L +VL P+ + +W T+PD R +P+TFI I WI + SYL+ W V GDT Sbjct: 699 KRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTA 758 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 +P + GLT LAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+ Sbjct: 759 RIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYG 818 Query: 405 LFYPSTPE 412 + Y + E Sbjct: 819 IIYGAPVE 826 Score = 44.8 bits (101), Expect = 0.004 Identities = 21/62 (33%), Positives = 34/62 (54%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ + L + D + G T +AAG S PE +SV+ +GI +GS F+IL + Sbjct: 359 LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 418 Query: 397 GL 398 G+ Sbjct: 419 GM 420 Score = 36.7 bits (81), Expect = 1.2 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 4/69 (5%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV---LAVP-ACCAL 178 I ++ G TF+AA +S P+L + + GD+ V + VGS +F+V L +P + Sbjct: 760 IPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYGI 819 Query: 179 FAGAVIELD 187 GA +E++ Sbjct: 820 IYGAPVEVN 828 >UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/potassium/calcium exchanger (Na(+)/K(+)/Ca(2+)-exchange protein); n=2; Endopterygota|Rep: PREDICTED: similar to Sodium/potassium/calcium exchanger (Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera Length = 658 Score = 167 bits (405), Expect = 6e-40 Identities = 73/158 (46%), Positives = 104/158 (65%) Query: 73 FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132 FP D T QR+ G ++LH +Y F+ L VC+++FVP++++I E+L IA D+AGATF Sbjct: 112 FPQDLFTVHQRRRGAVILHVIGVVYMFVALAIVCDEFFVPSLDVIIEKLEIADDVAGATF 171 Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVT 192 MAA S+PELF + +G FV+ D+G+G +VGSAVFN+L V CA+F+ V+ L WW + Sbjct: 172 MAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRTVLSLTWWPLF 231 Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RDC Y LI D+ I+W+EAL+L Y Y+ Sbjct: 232 RDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYV 269 Score = 122 bits (295), Expect = 1e-26 Identities = 55/123 (44%), Positives = 80/123 (65%), Gaps = 2/123 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+L ++L PI LW T+PD R + +TFI I WI + SYL+ W V GDT+ Sbjct: 469 KRLTYILVAPILFPLWLTLPDTRTPRGKKFFAVTFIGSIFWIAAYSYLMVWWANVAGDTV 528 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 +P + GLT LAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+ Sbjct: 529 RIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPVPWLLYG 588 Query: 405 LFY 407 L Y Sbjct: 589 LIY 591 Score = 44.4 bits (100), Expect = 0.006 Identities = 20/62 (32%), Positives = 34/62 (54%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ + L + D + G T +AAG S PE +S++ +GI +GS F+IL + Sbjct: 153 LDVIIEKLEIADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVI 212 Query: 397 GL 398 G+ Sbjct: 213 GM 214 Score = 37.1 bits (82), Expect = 0.88 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 + + I ++ G TF+AA +S P+L + + GD+ V + VGS +F+V Sbjct: 526 DTVRIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDV 576 >UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger, putative - Nasonia vitripennis Length = 692 Score = 166 bits (404), Expect = 9e-40 Identities = 72/166 (43%), Positives = 109/166 (65%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NC+P AI +FP + + R+HG +++H +A+Y FL L VC+DYFV +++ ICE L + Sbjct: 155 NCSPPAIEQFPRPLMGPYARKHGGLVIHVLVAIYTFLGLAIVCDDYFVASLDRICEELKL 214 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 + D+AGATFMAA SS+PEL +G F + D+GV V+GSAVFN++ V + C L + V Sbjct: 215 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVFNIMFVISVCGLCSSTV 274 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 +L+WW + RDC Y ++ T+ ++ I W EAL +++MY Y Sbjct: 275 SKLNWWPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMYGVY 320 Score = 137 bits (331), Expect = 6e-31 Identities = 57/121 (47%), Positives = 84/121 (69%), Gaps = 2/121 (1%) Query: 286 WKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDT 343 W W L +PI + T+PDCR + YP TF + + WI SY++ W+IT++G T Sbjct: 492 WGLFTWGLVYPIHYMGRLTMPDCRQEKYRNWYPFTFCISMIWISFYSYIMVWMITIIGST 551 Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L +PD++ GLT +AAG S+P+A+SS+ V K+G G M +SN++GSN FDIL+CLGLPW ++ Sbjct: 552 LGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGLGDMAVSNAVGSNVFDILVCLGLPWFIQ 611 Query: 404 S 404 + Sbjct: 612 T 612 Score = 37.9 bits (84), Expect = 0.50 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 331 YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390 Y VA + + + PD + G T +AAG+S PE + V+ +G+S IGS F Sbjct: 200 YFVASLDRICEELKLSPD-VAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVF 258 Query: 391 DILLCLGLPWLVKS 404 +I+ + + L S Sbjct: 259 NIMFVISVCGLCSS 272 Score = 35.5 bits (78), Expect = 2.7 Identities = 21/57 (36%), Positives = 28/57 (49%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 I II L I + G TF+AA S P+ + GD+ V VGS VF++L Sbjct: 545 ITIIGSTLGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGLGDMAVSNAVGSNVFDIL 601 >UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12; Euarchontoglires|Rep: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human) Length = 1099 Score = 166 bits (403), Expect = 1e-39 Identities = 72/159 (45%), Positives = 107/159 (67%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW + Sbjct: 499 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LIL LD I W E+LLL+L Y FY+ Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597 Score = 115 bits (276), Expect = 3e-24 Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 2/121 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW T+PD R + S + TF+ I WI SYL+ W VG+T+ Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETI 966 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S Sbjct: 967 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1026 Query: 405 L 405 L Sbjct: 1027 L 1027 Score = 47.2 bits (107), Expect = 8e-04 Identities = 21/59 (35%), Positives = 33/59 (55%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023 Query: 178 LFA 180 LF+ Sbjct: 1024 LFS 1026 >UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 639 Score = 164 bits (398), Expect = 5e-39 Identities = 72/183 (39%), Positives = 114/183 (62%) Query: 82 QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141 +R+HG +++H F+ LYCF+ L +C++YF ++E +C+RL I +D+AGATFMAA SS P Sbjct: 44 ERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAGSSMPT 103 Query: 142 LFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXX 201 LFI F+ EGD+G+G ++GS++FN+L + A C LF+G VI L W + RD +Y Sbjct: 104 LFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSCVYVVN 163 Query: 202 XXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTR 261 L++ + D+ I+++EAL+ ++YT YIL + D+ +G+EM Sbjct: 164 LVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFESAFETCCDINKGMEMVE 223 Query: 262 RHD 264 D Sbjct: 224 MED 226 Score = 133 bits (322), Expect = 7e-30 Identities = 54/121 (44%), Positives = 88/121 (72%), Gaps = 3/121 (2%) Query: 284 SFWKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVG 341 +F K++ W+ P+ L + T+PDCR + + YP TF + I W+ ++SY++ W ++++G Sbjct: 416 TFSKRIVWIFMLPVHLAFYVTMPDCRVKKWEAWYPATFALSIIWMAALSYVLVWTVSIIG 475 Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401 +T ++P+ I GLT+LAAG+S+P+ +SS++V K G G M ++N IGSN FD+ LCLGLPWL Sbjct: 476 ETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDV-LCLGLPWL 534 Query: 402 V 402 + Sbjct: 535 L 535 Score = 42.7 bits (96), Expect = 0.018 Identities = 18/50 (36%), Positives = 29/50 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 L +P + G T +AAG+S+P ++ G G +G+ IGS+ F+IL Sbjct: 83 LRIPTDVAGATFMAAGSSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNIL 132 Score = 37.1 bits (82), Expect = 0.88 Identities = 19/59 (32%), Positives = 32/59 (54%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 + II E +I I G T +AA SS P++ + + GD+ + +GS +F+VL + Sbjct: 471 VSIIGETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDVLCL 529 >UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein CG1090); n=5; Bilateria|Rep: Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein CG1090) - Drosophila melanogaster (Fruit fly) Length = 642 Score = 164 bits (398), Expect = 5e-39 Identities = 69/166 (41%), Positives = 110/166 (66%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 NCTP AI +FP + ++ RQHG ++LH +A++ F L VC++YFV +++ +CE L + Sbjct: 101 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKL 160 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 + D+AGATFMAA SS+PEL +G F + D+G+ V+GSAVFN++ V + CAL +G V Sbjct: 161 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTV 220 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 +L+WW + RDC Y +++ + +D I E+++++L Y Y Sbjct: 221 CQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGY 266 Score = 140 bits (340), Expect = 5e-32 Identities = 58/116 (50%), Positives = 83/116 (71%), Gaps = 2/116 (1%) Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348 W + +PI + T+PDCR + YP TF+M + WI SY + W+ITV+G TL +PD Sbjct: 449 WYVVYPIHFLCKKTMPDCRQEQYRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPD 508 Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 ++ GLT +AAG S+P+A+SS+ V K+G G M +SN+IGSN FDIL+CLGLPW +++ Sbjct: 509 TVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQT 564 Score = 36.7 bits (81), Expect = 1.2 Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + L + + G T +AAG+S PE + V+ +GIS IGS F+I+ + + Sbjct: 156 EELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISV 212 Score = 34.7 bits (76), Expect = 4.7 Identities = 20/62 (32%), Positives = 30/62 (48%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 + V I +I L I + G TF+AA S P+ + GD+ V +GS VF+ Sbjct: 492 FMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFD 551 Query: 169 VL 170 +L Sbjct: 552 IL 553 >UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exchanger; n=5; Coelomata|Rep: Potassium-dependent sodium-calcium exchanger - Aedes aegypti (Yellowfever mosquito) Length = 207 Score = 163 bits (397), Expect = 6e-39 Identities = 74/164 (45%), Positives = 106/164 (64%), Gaps = 1/164 (0%) Query: 73 FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132 FP D T QR++G ++LH +Y F+ L VC+++FVP++++I E+L I D+AGATF Sbjct: 1 FPEDLFTLEQRRNGAVVLHILGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 60 Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVT 192 MAA S+PELF + +G FV+ D+G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 61 MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTLLTLTWWPLF 120 Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY-ILEKIN 235 RDC Y LI D+ I W EAL+L ++Y Y + K N Sbjct: 121 RDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFN 164 Score = 44.8 bits (101), Expect = 0.004 Identities = 21/62 (33%), Positives = 34/62 (54%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ + L + D + G T +AAG S PE +SV+ +GI +GS F+IL + Sbjct: 42 LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 101 Query: 397 GL 398 G+ Sbjct: 102 GM 103 >UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF15008, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 557 Score = 163 bits (395), Expect = 1e-38 Identities = 69/137 (50%), Positives = 96/137 (70%) Query: 95 ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 A+Y FL L VC+ YFVP++E + E L+++ D+AGATFMAA SS+PELF + +G F+TEG Sbjct: 1 AIYMFLALAVVCDVYFVPSLEKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEG 60 Query: 155 DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214 D+GVG +VGSAVFN+L + C +FAG I L WW + RD + Y LIL + D+K+ Sbjct: 61 DVGVGTIVGSAVFNILVIIGICGIFAGQPISLSWWPLFRDAVFYILSILVLILVIYDEKV 120 Query: 215 YWHEALLLVLMYTFYIL 231 W E ++L+ MY YI+ Sbjct: 121 MWWETIILISMYGIYII 137 Score = 129 bits (311), Expect = 2e-28 Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%) Query: 291 WVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348 W+L+WP+ ++L T+P+C Y LTF+ WI SYL+ W++T++ TL +P+ Sbjct: 325 WLLSWPVSVLLHCTVPNCSLPQWERWYLLTFLTSTLWIALFSYLMVWMVTIISFTLGIPE 384 Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FD+LL LG PW +++L Sbjct: 385 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVLLGLGFPWALRTL 441 Score = 43.2 bits (97), Expect = 0.013 Identities = 18/59 (30%), Positives = 35/59 (59%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + + L++ + G T +AAG+S PE +S++ G +G+ +GS F+IL+ +G+ Sbjct: 23 LSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEGDVGVGTIVGSAVFNILVIIGI 81 Score = 37.1 bits (82), Expect = 0.88 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 + II L I I G TF+AA +S P+ + + GD+ V +GS +F+VL Sbjct: 373 VTIISFTLGIPEVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVL 429 >UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus norvegicus (Rat) Length = 1153 Score = 162 bits (393), Expect = 2e-38 Identities = 71/159 (44%), Positives = 104/159 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + R+ G+++LH F Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI+ LD I W E+LLL+L Y Y+ Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564 Score = 115 bits (277), Expect = 2e-24 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW TIPD R + + + +TF+ I WI SYL+ W VG+T+ Sbjct: 961 KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 1020 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S Sbjct: 1021 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1080 Query: 405 LFYPSTP 411 L P Sbjct: 1081 LINALQP 1087 Score = 50.0 bits (114), Expect = 1e-04 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ +T++ I Y V + V+ D L + + + G T +AAG S PE +S++ Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484 Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397 H +GI +GS F+IL +G Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 1018 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1077 Query: 178 LFA 180 LF+ Sbjct: 1078 LFS 1080 >UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus (Rat) Length = 1086 Score = 162 bits (393), Expect = 2e-38 Identities = 71/159 (44%), Positives = 104/159 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + R+ G+++LH F Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI+ LD I W E+LLL+L Y Y+ Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564 Score = 115 bits (277), Expect = 2e-24 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW TIPD R + + + +TF+ I WI SYL+ W VG+T+ Sbjct: 894 KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 953 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S Sbjct: 954 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1013 Query: 405 LFYPSTP 411 L P Sbjct: 1014 LINALQP 1020 Score = 50.0 bits (114), Expect = 1e-04 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ +T++ I Y V + V+ D L + + + G T +AAG S PE +S++ Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484 Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397 H +GI +GS F+IL +G Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 951 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1010 Query: 178 LFA 180 LF+ Sbjct: 1011 LFS 1013 >UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1; n=2; Eutheria|Rep: Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1 - Mus musculus (Mouse) Length = 1130 Score = 162 bits (393), Expect = 2e-38 Identities = 71/159 (44%), Positives = 104/159 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + R+ G+++LH F +Y F+ L VC++YFVPA+ +I +L I+ D+AGAT Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGAT 465 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI+ LD I W E+LLL+L Y Y+ Sbjct: 526 FRDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYV 564 Score = 116 bits (280), Expect = 9e-25 Identities = 56/127 (44%), Positives = 81/127 (63%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW TIPD R + S + +TF+ I WI SYL+ W VG+T+ Sbjct: 938 KQAIYLFLLPIVFPLWLTIPDVRRQESRKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 997 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S Sbjct: 998 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1057 Query: 405 LFYPSTP 411 L P Sbjct: 1058 LINALQP 1064 Score = 44.8 bits (101), Expect = 0.004 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ + ++ I Y V + V+ L + + + G T +AAG S PE +S++ Sbjct: 426 IFGMMYVFVALAIVCDEYFVP-ALGVITHKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484 Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397 H +GI +GS F+IL +G Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 995 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1054 Query: 178 LFA 180 LF+ Sbjct: 1055 LFS 1057 >UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13; Fungi/Metazoa group|Rep: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Rattus norvegicus (Rat) Length = 1181 Score = 162 bits (393), Expect = 2e-38 Identities = 71/159 (44%), Positives = 104/159 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + R+ G+++LH F Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI+ LD I W E+LLL+L Y Y+ Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564 Score = 115 bits (277), Expect = 2e-24 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+ ++ PI LW TIPD R + + + +TF+ I WI SYL+ W VG+T+ Sbjct: 989 KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 1048 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S Sbjct: 1049 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1108 Query: 405 LFYPSTP 411 L P Sbjct: 1109 LINALQP 1115 Score = 50.0 bits (114), Expect = 1e-04 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ +T++ I Y V + V+ D L + + + G T +AAG S PE +S++ Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484 Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397 H +GI +GS F+IL +G Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 1046 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1105 Query: 178 LFA 180 LF+ Sbjct: 1106 LFS 1108 >UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).; n=1; Takifugu rubripes|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5). - Takifugu rubripes Length = 473 Score = 160 bits (388), Expect = 7e-38 Identities = 70/168 (41%), Positives = 106/168 (63%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 +C P EFP T +R+ G ++++ + Y L + VC+DYF+P++E+I ERL + Sbjct: 1 DCVPPQSSEFPDGFFTVQERKDGGLVIYFLIIFYMLLAVSIVCDDYFLPSLEVISERLGL 60 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 + D+AGATFMAA SS+PEL +G FVT+GD+GV +VGSAV+N+L + A C L Sbjct: 61 SQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTVA 120 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 L W + RDC+ Y +I + D+K+YW++A L+L+Y YI+ Sbjct: 121 GRLTCWPLFRDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIV 168 Score = 142 bits (343), Expect = 2e-32 Identities = 64/141 (45%), Positives = 95/141 (67%), Gaps = 6/141 (4%) Query: 268 SDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITW 325 S SV++ P + K++FWVL+ PI +L+ T PDCR + +TF M W Sbjct: 270 SPAEQKSVFAMPESDL---KRIFWVLSLPIITLLFLTTPDCRRSFWKKWFMVTFFMSAVW 326 Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 I +Y++ W++TVVG+TL +PD++ GLT+LAAGTS+P+ V+SV+V ++G M +SN + Sbjct: 327 ISGFTYILVWMVTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIV 386 Query: 386 GSNTFDILLCLGLPWLVKSLF 406 GSN FD +LCLGLPW +K+ F Sbjct: 387 GSNVFD-MLCLGLPWFIKTAF 406 Score = 41.5 bits (93), Expect = 0.041 Identities = 18/57 (31%), Positives = 33/57 (57%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 + V+ + L + + G T +AAG+S PE V++ L G +G+S +GS +++L Sbjct: 51 LEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLL 107 Score = 35.1 bits (77), Expect = 3.6 Identities = 16/59 (27%), Positives = 32/59 (54%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 + ++ E L I + G T +AA +S P+ + + + D+ + +VGS VF++L + Sbjct: 338 VTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDMLCL 396 >UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - Morone saxatilis (Striped bass) Length = 749 Score = 160 bits (388), Expect = 7e-38 Identities = 69/159 (43%), Positives = 105/159 (66%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 ++P D + QRQ G+++LH +Y F+ L VC+++FVP +E+I +L I+ D+AGAT Sbjct: 140 DYPEDLFSVEQRQQGWVVLHVIGMIYMFVALAIVCDEFFVPGLEVITNKLQISDDVAGAT 199 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V CA+F+ ++ L WW + Sbjct: 200 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSREMLHLTWWPL 259 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI+ LD+ I W E++LLVL Y Y+ Sbjct: 260 FRDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYV 298 Score = 119 bits (287), Expect = 1e-25 Identities = 56/127 (44%), Positives = 85/127 (66%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K++ ++L PI LW T+PD R+ S + +TFI I WIG SY++ W VG+T+ Sbjct: 557 KQVTYLLLLPIVFPLWLTLPDVRNLASRKYFVITFIGSILWIGVFSYMMVWWAHQVGETV 616 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ + Sbjct: 617 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITIGLPVPWLIYT 676 Query: 405 LFYPSTP 411 L + P Sbjct: 677 LLHNGEP 683 Score = 48.0 bits (109), Expect = 5e-04 Identities = 21/62 (33%), Positives = 35/62 (56%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL + Sbjct: 182 LEVITNKLQISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI 241 Query: 397 GL 398 G+ Sbjct: 242 GM 243 Score = 37.1 bits (82), Expect = 0.88 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 614 ETVGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 664 >UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=1; Aedes aegypti|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 520 Score = 159 bits (386), Expect = 1e-37 Identities = 65/160 (40%), Positives = 104/160 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 + P D ++ +R +G I+LH A+Y F +L VC +YF+P++E ICE L+++ D+A AT Sbjct: 69 DLPPDLFSKTERLNGAIILHFLAAIYFFTILAYVCSEYFLPSVEYICEDLHLSEDVAAAT 128 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMA A+S PE F N + T V + D+G+G ++GS +FN L V A L + ++LDWW + Sbjct: 129 FMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTKSHVKLDWWPL 188 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 TRD ++ L+ L D+++YW+E+L+ V++Y Y L Sbjct: 189 TRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFL 228 Score = 152 bits (369), Expect = 1e-35 Identities = 68/145 (46%), Positives = 98/145 (67%), Gaps = 2/145 (1%) Query: 263 HDSTG-SDISTSSVWSFPGDKISFWKKLFW-VLTWPIRLILWATIPDCRHRHSIYPLTFI 320 +DS+G SD S S W +FW TWP R+I+ TIPD R +YPLTF Sbjct: 299 YDSSGESDQSDDSRMHLLKISKDSWLGVFWWFYTWPFRVIVNVTIPDPRKHRKLYPLTFF 358 Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380 MCI WIG +Y+V W++T++G T +VP+++ GLT LA G +PEAVS++ V ++G+G+MG Sbjct: 359 MCIAWIGGTAYMVFWMMTIIGSTFDVPETVMGLTFLAFGGCMPEAVSAITVIRKGNGSMG 418 Query: 381 ISNSIGSNTFDILLCLGLPWLVKSL 405 +SNS+G+NT IL LGLPW ++++ Sbjct: 419 VSNSLGANTLAILFSLGLPWFIRNM 443 Score = 34.3 bits (75), Expect = 6.2 Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 312 HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV 371 H + + F + ++ S +L + + + + L++ + + T +A TS+PE ++ + Sbjct: 88 HFLAAIYFFTILAYVCSEYFLPS--VEYICEDLHLSEDVAAATFMATATSMPEFFTNTIS 145 Query: 372 TKQGHGTMGISNSIGSNTFDIL 393 T MG+ +GS F+ L Sbjct: 146 TLVVDSDMGLGTIMGSMLFNTL 167 >UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo sapiens (Human) Length = 661 Score = 158 bits (384), Expect = 2e-37 Identities = 71/168 (42%), Positives = 107/168 (63%) Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123 N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170 Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 + D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ + Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230 Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 + L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++ Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278 Score = 127 bits (306), Expect = 6e-28 Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%) Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285 +E N MTP S VQNG+L IE + + S+ ++P + Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468 Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343 K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527 Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+ Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587 Query: 404 SLFYPSTP 411 ++ + P Sbjct: 588 TVIHRFQP 595 Score = 50.8 bits (116), Expect = 7e-05 Identities = 22/62 (35%), Positives = 36/62 (58%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 +TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL + Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220 Query: 397 GL 398 G+ Sbjct: 221 GM 222 Score = 37.5 bits (83), Expect = 0.67 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576 >UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 643 Score = 158 bits (383), Expect = 3e-37 Identities = 72/162 (44%), Positives = 105/162 (64%), Gaps = 2/162 (1%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D T Q+Q G ++ H Y FL L C+++FVP++ +I E+L + D+AGAT Sbjct: 92 EYPEDEFTLEQKQQGAVICHIIGMCYMFLALAIACDEFFVPSLTVIIEKLELKEDVAGAT 151 Query: 132 FMAAASSSPELFINCVGTFV-TEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWS 190 FMAA S+PELF + +GTF+ + ++G+G +VGSAVFNVL V CA+F+ V+EL WW Sbjct: 152 FMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVLELTWWP 211 Query: 191 VTRDCMMYXXXXXXLILTLLD-DKIYWHEALLLVLMYTFYIL 231 + RDC+ Y LI+ L D I W E+L+L+L Y Y++ Sbjct: 212 LFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVI 253 Score = 119 bits (287), Expect = 1e-25 Identities = 55/119 (46%), Positives = 80/119 (67%), Gaps = 2/119 (1%) Query: 288 KLFWVLTWPIRLILWATIPDCRH--RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345 ++F+V+ P+ +++ T+ D R R +YP+TF+M I WI SY + W T VG T + Sbjct: 458 RVFYVIKAPLMFLMYYTMVDVRRPERRHLYPITFLMSIFWIAFFSYFMVWWATEVGYTFD 517 Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 +P + GLT LAAGTS+P+ ++SVLV ++G G M +S+SIGSN FDI + L LPWL S Sbjct: 518 IPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWLCYS 576 Score = 40.7 bits (91), Expect = 0.072 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVT-KQGHGTMGISNSIGSNTFDILLC 395 +TV+ + L + + + G T +AAG S PE +S + T +GI +GS F++L Sbjct: 134 LTVIIEKLELKEDVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFV 193 Query: 396 LGL 398 +G+ Sbjct: 194 IGM 196 Score = 38.7 bits (86), Expect = 0.29 Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 8/116 (6%) Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV---LAVPACC-- 176 +I +++ G TF+AA +S P+L + + GD+ V + +GS +F++ L +P C Sbjct: 517 DIPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWLCYS 576 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL-VLMYTFYIL 231 A+ G + + + +M +++++ + W + L M+ FYI+ Sbjct: 577 AVNLGLAVNVSSRGILYSVIMLFCMLIAVVVSIAASR--WRMSKSLGACMFVFYII 630 >UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13 SCAF14555, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 647 Score = 157 bits (380), Expect = 7e-37 Identities = 69/160 (43%), Positives = 104/160 (65%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D + R+ G+++LH +Y F+ L VC+++FVPA+ +I +L I+ D+AGAT Sbjct: 132 EYPEDLFSIKDRRRGWVVLHIIGMMYMFIALAIVCDEFFVPALGVITHKLAISDDVAGAT 191 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ V+ L WW + Sbjct: 192 FMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREVLHLTWWPL 251 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 RD Y LI+ LD+ I W E+++LV YT Y++ Sbjct: 252 FRDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVI 291 Score = 100 bits (239), Expect = 8e-20 Identities = 45/105 (42%), Positives = 68/105 (64%) Query: 307 DCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366 D + + +TF+ I WI SYL+ W VG+T+ + + I GLTILAAGTS+P+ + Sbjct: 477 DKKKSRRFFVVTFLGSILWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLI 536 Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTP 411 +SV+V ++G G M +S+S+GSN FDI + L +PWL+ S + P Sbjct: 537 TSVIVARKGMGDMAVSSSVGSNIFDITVGLPVPWLMYSAIHGLAP 581 Score = 46.0 bits (104), Expect = 0.002 Identities = 21/60 (35%), Positives = 33/60 (55%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 V+ L + D + G T +AAG S PE +S++ H +GI +GS F+IL +G+ Sbjct: 176 VITHKLAISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 235 Score = 37.9 bits (84), Expect = 0.50 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 512 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGMGDMAVSSSVGSNIFDI 562 >UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep: Slc24a2 protein - Mus musculus (Mouse) Length = 711 Score = 155 bits (377), Expect = 2e-36 Identities = 68/160 (42%), Positives = 103/160 (64%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I+ D+AGAT Sbjct: 120 DYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGAT 179 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ ++ L WW + Sbjct: 180 FMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPL 239 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 RD Y LI LD+ I W E+LLL+ Y Y++ Sbjct: 240 FRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVV 279 Score = 124 bits (300), Expect = 3e-27 Identities = 70/188 (37%), Positives = 104/188 (55%), Gaps = 7/188 (3%) Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285 +E N MTP S VQNG+L IE +T + + Sbjct: 458 IELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWPTNT 517 Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343 K+ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T Sbjct: 518 RKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 577 Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+ Sbjct: 578 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 637 Query: 404 SLFYPSTP 411 ++ + +P Sbjct: 638 TIIHRFSP 645 Score = 50.8 bits (116), Expect = 7e-05 Identities = 22/62 (35%), Positives = 36/62 (58%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 +TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL + Sbjct: 162 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 221 Query: 397 GL 398 G+ Sbjct: 222 GM 223 Score = 37.5 bits (83), Expect = 0.67 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 576 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 626 >UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).; n=1; Takifugu rubripes|Rep: Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2). - Takifugu rubripes Length = 449 Score = 155 bits (376), Expect = 2e-36 Identities = 70/159 (44%), Positives = 105/159 (66%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 ++P+D T +R+ G+++LH F LY F+ L VC+++FVPA+ +I E+L I+ D+AGAT Sbjct: 2 DYPTDLFTIEERRQGYVVLHMFGMLYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 61 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PELF + +G FV+ ++G+G +VGSAVFN+L V CALF+ V+ L WW + Sbjct: 62 FMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKEVLHLTWWPL 121 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 RD Y LI LD++I E++ L+ Y Y+ Sbjct: 122 FRDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYV 160 Score = 116 bits (279), Expect = 1e-24 Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 2/127 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K++ +++ PI LW T+PD R S +P+TFI I+WI SYL+ W VG+T Sbjct: 257 KQITYLVILPIVFPLWLTLPDVRRESSERFFPITFIGSISWIAFFSYLMVWWAHQVGETF 316 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 V + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L PWL+ + Sbjct: 317 WVTEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLLFN 376 Query: 405 LFYPSTP 411 + P Sbjct: 377 IINDFQP 383 Score = 52.4 bits (120), Expect = 2e-05 Identities = 23/62 (37%), Positives = 36/62 (58%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 +TV+ + L + D + G T +AAG S PE +SV+ H +GI +GS F+IL + Sbjct: 44 LTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVI 103 Query: 397 GL 398 G+ Sbjct: 104 GM 105 Score = 34.3 bits (75), Expect = 6.2 Identities = 15/47 (31%), Positives = 27/47 (57%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 + +I G T +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 318 VTEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 364 >UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis elegans Length = 596 Score = 155 bits (376), Expect = 2e-36 Identities = 63/158 (39%), Positives = 106/158 (67%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 +FP D + QRQ+GF++LH +Y F+ L VC+++FVP+++++ E+L+++ D+AGAT Sbjct: 86 QFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVLTEKLSLSDDVAGAT 145 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PE F + +G F+ + ++G+G +VGSA FN+L V A C LF+ ++++L WW + Sbjct: 146 FMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSKSILDLTWWPL 205 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 RD +Y L+ +D+ I + EAL + +Y Y Sbjct: 206 FRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVY 243 Score = 127 bits (307), Expect = 5e-28 Identities = 56/118 (47%), Positives = 81/118 (68%), Gaps = 2/118 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K+L +VL P+ + +W TIPD R H +YP TFI+ I WI SYL+ W +G+T Sbjct: 395 KRLTYVLLAPVVIPMWVTIPDVRKSHNRGLYPATFIISILWIAFFSYLMVWWANTIGETF 454 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 +P I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+ Sbjct: 455 VIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLL 512 Score = 44.0 bits (99), Expect = 0.008 Identities = 22/60 (36%), Positives = 34/60 (56%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ + L++ D + G T +AAG S PE +SV+ +GI +GS TF+IL L Sbjct: 128 LDVLTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVL 187 Score = 35.9 bits (79), Expect = 2.0 Identities = 19/53 (35%), Positives = 30/53 (56%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 I E I ++I G T +AA +S P+L + + GD+ V + VGS +F+V Sbjct: 450 IGETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDV 502 >UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exchanger, putative; n=2; Culicidae|Rep: Potassium-dependent sodium-calcium exchanger, putative - Aedes aegypti (Yellowfever mosquito) Length = 549 Score = 154 bits (374), Expect = 4e-36 Identities = 65/165 (39%), Positives = 105/165 (63%), Gaps = 1/165 (0%) Query: 68 AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127 +AI E P D T+ QR G I+LH A+Y F LL + +YF+P++E ICE L + D+ Sbjct: 86 SAIDELPDDVFTQEQRLQGAIILHFIGAIYFFTLLAYIVGEYFLPSVECICEDLKLTQDV 145 Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187 A ATFMA A + PE F N + TF+ + D+G+G ++GS +FN L V L ++LD Sbjct: 146 AAATFMAIAGTIPEFFTNTISTFIADSDMGIGTIMGSLLFNTLGVACLAGLACKKPVQLD 205 Query: 188 WWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALL-LVLMYTFYIL 231 WW +TRDC+++ L+ D +IYW+E+++ ++L++T++++ Sbjct: 206 WWPITRDCIVFAFHISVLVGFAWDGRIYWYESMVFVILLFTYFVV 250 Score = 138 bits (333), Expect = 3e-31 Identities = 64/178 (35%), Positives = 112/178 (62%), Gaps = 7/178 (3%) Query: 240 SQRMTPRSVQNGDLERGIEMTRRHDSTGSD-ISTSSVWSFPGDKISFWKKLFWVLTWPIR 298 S +M + ++ GDL+ + RH ++ S+W + + + ++W+ +WPIR Sbjct: 312 SDQMAEKPMKVGDLQ----IPSRHVLPDTEEYPPMSLWKIARE--TKLRTIWWLYSWPIR 365 Query: 299 LILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAA 358 +L TIP+ + YPLTFIMCI +IG S+L W+++++G TL +PD + GLT LA Sbjct: 366 FVLTFTIPNPTYMRRWYPLTFIMCIIFIGLTSFLTFWMMSIIGYTLGIPDGVMGLTFLAM 425 Query: 359 GTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416 G +PEA+S+VL+ + G+G +G+SN++G+N+ I+ LGLPW ++++ ++ N +V Sbjct: 426 GGCMPEAISAVLIIRTGNGAVGVSNALGANSLSIVFSLGLPWFIRTVADGASTTNAYV 483 >UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ncx-5 - Caenorhabditis elegans Length = 591 Score = 149 bits (360), Expect = 2e-34 Identities = 67/158 (42%), Positives = 99/158 (62%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 +FP+D + R+ G +++H L +Y F+ L VC+++FVP++ +I E L I+ D+AGAT Sbjct: 18 QFPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVLAISDDVAGAT 77 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191 FMAA S+PE F + G FV + ++GVG +VGSA FN+L V A C LF+ V+ L WW + Sbjct: 78 FMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPL 137 Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 RD Y L++ D+ I W EAL++ MY Y Sbjct: 138 FRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAY 175 Score = 114 bits (274), Expect = 5e-24 Identities = 53/118 (44%), Positives = 76/118 (64%), Gaps = 2/118 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 KKL ++ PI L T+PD R + +TFI I WI + SYL+ W +G+T Sbjct: 392 KKLIYLFLAPITFPLAYTLPDVRKPSLRKFFAITFIGAILWIAAYSYLMVWWANTIGETF 451 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 +P I GLTILAAGTS+P+ ++SV+V ++G G M +S+SIGSN FD+ + L +PWL+ Sbjct: 452 GIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDVCVGLPIPWLI 509 Score = 43.2 bits (97), Expect = 0.013 Identities = 20/60 (33%), Positives = 33/60 (55%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 ++V+ + L + D + G T +AAG S PE +S+ +G+ +GS TF+IL L Sbjct: 60 LSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVL 119 Score = 35.9 bits (79), Expect = 2.0 Identities = 18/53 (33%), Positives = 30/53 (56%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 I E I ++I G T +AA +S P+L + + GD+ V + +GS +F+V Sbjct: 447 IGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDV 499 >UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).; n=2; Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5). - Xenopus tropicalis Length = 555 Score = 148 bits (359), Expect = 2e-34 Identities = 65/136 (47%), Positives = 104/136 (76%), Gaps = 7/136 (5%) Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331 SV++ P + + K++ WVL+ PI +L+ T+PDCR + +++ LTF+M WI +V+Y Sbjct: 348 SVFTMPENDL---KRIIWVLSLPIITLLYLTVPDCRRKRWKNLFILTFLMSAVWISAVTY 404 Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ-GHGTMGISNSIGSNTF 390 ++ W++TVVG+TL++PD++ GLT+LAAGTS+P+ V+SVLV ++ G G M +SN +GSN F Sbjct: 405 ILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVF 464 Query: 391 DILLCLGLPWLVKSLF 406 D +LCLG+PW +K++F Sbjct: 465 D-MLCLGVPWFIKTVF 479 Score = 129 bits (312), Expect = 1e-28 Identities = 68/174 (39%), Positives = 100/174 (57%), Gaps = 9/174 (5%) Query: 59 VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIIC 118 +E E C + EFP D T +R+ G +++H + LY FL + VCE YF+P++E+I Sbjct: 1 LENETLCIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVIS 60 Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV-PACCA 177 ERL ++ D+AGATFMA SS+PE +G FVT+GD+GV +VGSAV+N+L + ACC Sbjct: 61 ERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCL 120 Query: 178 LFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 L + L W M + T+ D +E+ L+L+Y YI+ Sbjct: 121 LSLSLLYMLKVWRYVCPWMYFS--------TIHWDAWNRYESASLILIYGIYIV 166 Score = 41.1 bits (92), Expect = 0.054 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL-LC 395 + V+ + L + + G T +A G+S PE V+ L G +G+S +GS +++L +C Sbjct: 56 LEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGIC 115 Query: 396 LGLPWLVKSLFY 407 L SL Y Sbjct: 116 AACCLLSLSLLY 127 Score = 36.3 bits (80), Expect = 1.5 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINC-VGTFVTEGDLGVGAVVGSAVFNVLAV 172 + ++ E L+I + G T +AA +S P+ + V +GD+ + +VGS VF++L + Sbjct: 410 VTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVFDMLCL 469 >UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7; Murinae|Rep: Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus musculus (Mouse) Length = 501 Score = 148 bits (358), Expect = 3e-34 Identities = 63/167 (37%), Positives = 103/167 (61%) Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124 C + EFP T+ + G I+++ + LY + + VC+ YF+P++EII + L ++ Sbjct: 46 CAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLS 105 Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 D+AGATFMAA SS+PEL +G F+T+GD+G+ ++GSA++N+L + A C L + V Sbjct: 106 QDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVS 165 Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 L W + RDC +Y + + D++IYW+E L+L+Y Y+L Sbjct: 166 TLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVL 212 Score = 144 bits (349), Expect = 4e-33 Identities = 65/135 (48%), Positives = 96/135 (71%), Gaps = 6/135 (4%) Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331 SV+S P + +++FWVL+ PI +L T PDCR + + + +TF M WI + +Y Sbjct: 295 SVFSMPEADL---RRIFWVLSLPIITLLALTTPDCRRKFWKNYFVITFFMSALWISAFTY 351 Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 ++ W++TV G+TL +PD++ GLT+LAAGTS+P+ V+SVLV ++G G M ISN +GSN FD Sbjct: 352 ILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFD 411 Query: 392 ILLCLGLPWLVKSLF 406 +LCLGLPW +K+ F Sbjct: 412 -MLCLGLPWFIKTAF 425 Score = 42.7 bits (96), Expect = 0.018 Identities = 19/57 (33%), Positives = 34/57 (59%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 + ++ D+L + + G T +AAG+S PE V++ L G +GIS +GS +++L Sbjct: 95 LEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLL 151 Score = 36.7 bits (81), Expect = 1.2 Identities = 17/59 (28%), Positives = 32/59 (54%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 + + E L I + G T +AA +S P+ + + +GD+ + +VGS VF++L + Sbjct: 357 VTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDMLCL 415 >UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis pacifica SIR-1 Length = 361 Score = 147 bits (355), Expect = 7e-34 Identities = 103/314 (32%), Positives = 153/314 (48%), Gaps = 26/314 (8%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV--TE 153 L F + +V E F+ +++ I ER+ ++S +AGAT +A +S+PEL V F Sbjct: 11 LVAFYAMSAVVEGPFMASLDRIAERMGLSSSVAGATLLAFGTSAPELSTALVALFAEGAH 70 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 GVG++VGSA+F +L V A+ + LDW V RD + Y LI + DD+ Sbjct: 71 ASTGVGSIVGSAIFQILVVVGFAAVVRAST--LDWRPVIRDALFYALSIVLLIAFVHDDR 128 Query: 214 IYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTS 273 + EA +LV Y Y+ + R V + E +E D + Sbjct: 129 LTLVEAAILVGSYGLYL--------GVMWIWTRRVDEPEPEPELEPEPEVDPEAPE---- 176 Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLV 333 PG + +L LTWPI +L A +PD + F + + IG Y + Sbjct: 177 -----PGP----FARLRRALTWPIDRLL-ALVPDPASQARWTLPVFALSLGLIGFSCYWL 226 Query: 334 AWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 + + L VP +I LTILA G+S+PE VSS V +QG M ++N++GSN FDIL Sbjct: 227 VFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFDIL 286 Query: 394 LCLGLPWLVKSLFY 407 + LGLP L+ L + Sbjct: 287 VSLGLPVLLYCLLH 300 Score = 37.9 bits (84), Expect = 0.50 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 7/137 (5%) Query: 101 LLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGA 160 L+G C + V A E I + L + I T +A SS PEL + D+ V Sbjct: 218 LIGFSCY-WLVFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVAN 276 Query: 161 VVGSAVFNV---LAVPACC-ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216 VGS +F++ L +P L G ++ L ++T ++ ++ L + Sbjct: 277 AVGSNIFDILVSLGLPVLLYCLLHGDLVGLGGATITSSLVLLGATLAMVVGLLAAQRFRA 336 Query: 217 HEAL--LLVLMYTFYIL 231 A LL+ Y Y++ Sbjct: 337 SRAFGALLISAYAAYVV 353 >UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis (Starfish) Length = 616 Score = 144 bits (350), Expect = 3e-33 Identities = 84/239 (35%), Positives = 134/239 (56%), Gaps = 16/239 (6%) Query: 2 LIRTRQYERKHRVATIVRVVLFFGI----PIVYMVAKSIASNQVIVFDEPEAFSSRHLLG 57 ++ TR +K +VR+ + FGI +++ ++ ASN EP +++R LLG Sbjct: 20 IMLTRPSTKKLGTRWLVRIGILFGIFATSTLIFALSSVGASNA-----EPSMYNTRQLLG 74 Query: 58 IVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEII 117 + + + + + F+ ++ L F+ L +C+D+FVP++E I Sbjct: 75 TGDTNATVVDSCTTLYEVNHVPGL-----FVTIYIILIFVLFISLAIICDDFFVPSLEAI 129 Query: 118 CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCA 177 ERL ++ D+AGATFMAA SS+PELFI+ +G E D+GVG +VG+AVFN+L + A A Sbjct: 130 SERLELSEDVAGATFMAAGSSAPELFISIIGV-SKESDVGVGTIVGTAVFNILIIIALTA 188 Query: 178 LFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI-LEKIN 235 AG V++LDW + RDC+ Y I+ D I +EA++L+ +Y YI L K+N Sbjct: 189 ALAGQVLKLDWRPLVRDCISYGISIICFIIFAWDGVIEIYEAIILLGLYVAYIVLMKLN 247 Score = 95.9 bits (228), Expect = 2e-18 Identities = 49/129 (37%), Positives = 77/129 (59%), Gaps = 3/129 (2%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K +++++P TIP+C + +Y ++F+M I WI +S + ++ G L Sbjct: 414 KWAMFIVSFPFMCAFTWTIPNCSNPKYKRLYLVSFLMSIVWIAGLSTAMVTLVERAGCIL 473 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 N+ GL +A GTS+P+A+SS+LV + G G M +SN+IGSN FDI L LGLP+ ++ Sbjct: 474 NIDHYFMGLVFVAVGTSVPDALSSILVARDGFGDMAVSNAIGSNVFDINLGLGLPFFIRI 533 Query: 405 LFYPSTPEN 413 L S+P N Sbjct: 534 LI-TSSPIN 541 Score = 38.7 bits (86), Expect = 0.29 Identities = 18/63 (28%), Positives = 37/63 (58%), Gaps = 3/63 (4%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLC 395 + + + L + + + G T +AAG+S PE S++ V+K+ +G+ +G+ F+IL+ Sbjct: 126 LEAISERLELSEDVAGATFMAAGSSAPELFISIIGVSKE--SDVGVGTIVGTAVFNILII 183 Query: 396 LGL 398 + L Sbjct: 184 IAL 186 >UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 209 Score = 144 bits (348), Expect = 5e-33 Identities = 62/116 (53%), Positives = 89/116 (76%), Gaps = 1/116 (0%) Query: 63 RNCTPAAILEFPSDGLTRFQRQ-HGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121 +NC +I +FPSD +T++QRQ G I+ H F+A+Y F L +VC++YFV ++E IC+ L Sbjct: 65 KNCVNPSISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCDEYFVSSLERICDGL 124 Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCA 177 N+ SD+AGATFMAA SS+PE F + +G F+T+GD+G+G +VGSAVFN+L + A CA Sbjct: 125 NLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAICA 180 Score = 43.2 bits (97), Expect = 0.013 Identities = 21/57 (36%), Positives = 32/57 (56%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 D LN+ + G T +AAG+S PE +SV+ G +GI +GS F+IL + + Sbjct: 122 DGLNLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAI 178 >UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).; n=2; Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3). - Xenopus tropicalis Length = 524 Score = 141 bits (341), Expect = 4e-32 Identities = 61/112 (54%), Positives = 82/112 (73%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 EFP D + R+HG ++LH A+Y F L VC+D+FVP++E I ERL ++ D+AGAT Sbjct: 1 EFPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAGAT 60 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 FMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG V Sbjct: 61 FMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQV 112 Score = 135 bits (327), Expect = 2e-30 Identities = 56/120 (46%), Positives = 89/120 (74%), Gaps = 2/120 (1%) Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345 K+ W++TWP+ L+L+ T+P+C + +TF+ WI ++SY++ W++T++G TL Sbjct: 333 KVKWMVTWPLCLLLYFTVPNCAKPRWEKWFMVTFVSSSMWIAALSYVMVWMVTIIGFTLG 392 Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +PD I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L Sbjct: 393 IPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 452 Score = 44.0 bits (99), Expect = 0.008 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + L + + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+ Sbjct: 46 ISERLQLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVC 105 Query: 400 WL----VKSLFYPSTP 411 L V+S+ S P Sbjct: 106 GLFAGQVRSMLLVSLP 121 Score = 36.3 bits (80), Expect = 1.5 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 + II L I I G TF+AA +S P+ + + GD+ V +GS VF++L Sbjct: 384 VTIIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 440 >UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger-like protein; n=1; Microscilla marina ATCC 23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like protein - Microscilla marina ATCC 23134 Length = 389 Score = 141 bits (341), Expect = 4e-32 Identities = 95/322 (29%), Positives = 153/322 (47%), Gaps = 10/322 (3%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 I L + L F ++ + + +F+ +++ I E + + +AGAT +A +S+PE+ Sbjct: 3 IWLALVVILLAFYVMTEIVDRHFIKSLDNIAEWMKLPPSVAGATLLALGTSAPEISTALF 62 Query: 148 GTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXL 205 F+ + GVG +VGSA+F +L V A+ + L+W V RD + Y L Sbjct: 63 ALFLEGANPATGVGTIVGSAIFQILVVIGFAAVVKTSY--LNWRPVMRDSIFYAFSVGLL 120 Query: 206 ILTLLDDKIYWHEALLLVLMYTFY--ILEKINPLDASQRMTPRS---VQNGDLERGIEMT 260 IL + D+K E + V Y Y +L + TP++ G E Sbjct: 121 ILFVADNKFTLIEGIAFVCSYFLYLFVLFLWTKYVNEEATTPKNGFETPAGSARAEFEGA 180 Query: 261 RRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFI 320 H T I + + +K L L +P+ ++ IPD + F+ Sbjct: 181 AHHLDTPRPIEAIEKDMEDETRRNPFKILQKTLGYPVEFLM-NLIPDPEEKPRWTIPVFL 239 Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380 + + I SY + + +++P +I LTILA G+S+PE +SS +V KQG G M Sbjct: 240 LSLVIIAGASYFLVVAAEALAKAMDIPPAIIALTILAGGSSIPEMISSAIVAKQGRGDMA 299 Query: 381 ISNSIGSNTFDILLCLGLPWLV 402 I+N+IGSN FDIL+ LGLP L+ Sbjct: 300 IANAIGSNIFDILMSLGLPVLI 321 >UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium exchanger; n=2; Eumetazoa|Rep: Testis potassium dependent sodium/calcium exchanger - Strongylocentrotus purpuratus (Purple sea urchin) Length = 652 Score = 140 bits (339), Expect = 6e-32 Identities = 64/152 (42%), Positives = 97/152 (63%), Gaps = 2/152 (1%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 +++ + + F+ + +C+D+FVP++E+I E L+++ D+AGATFMAA SS+PELF Sbjct: 113 WVIFYAIFVIILFIAIAIICDDFFVPSLEVISETLSLSEDVAGATFMAAGSSAPELFTAV 172 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 +G E D+GVG +VGSAVFN+L + A A AG V+ LDW + RD Y I Sbjct: 173 IGV-AFESDVGVGTIVGSAVFNILIIIALTAALAGQVLNLDWRPLARDSFFYGLSLVCFI 231 Query: 207 LTLLDDKIYWHEALLLVLMYTFY-ILEKINPL 237 + D + W E+L+LV++Y Y IL K+NP+ Sbjct: 232 VFSWDTEFTWWESLILVILYVIYLILMKVNPI 263 Score = 101 bits (243), Expect = 3e-20 Identities = 48/119 (40%), Positives = 77/119 (64%), Gaps = 2/119 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 K L +V+++P TIP+C Y +F++ I WI ++S+ + ++ +G L Sbjct: 448 KWLLFVISFPFMCAFSWTIPNCSVPRLRKWYVASFLLSIFWIAALSFGMVTLVVKIGCIL 507 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 N+ D GL I+A GTS+P+A+SS+LV + G+G M +SN+IGSN FDI L +GLP+L++ Sbjct: 508 NISDYTMGLVIVAVGTSVPDALSSILVARDGYGDMAVSNAIGSNVFDINLGIGLPYLIR 566 Score = 42.3 bits (95), Expect = 0.023 Identities = 19/62 (30%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 + V+ +TL++ + + G T +AAG+S PE ++V + +G+ +GS F+IL+ + Sbjct: 140 LEVISETLSLSEDVAGATFMAAGSSAPELFTAV-IGVAFESDVGVGTIVGSAVFNILIII 198 Query: 397 GL 398 L Sbjct: 199 AL 200 >UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaster|Rep: CG17167-PA - Drosophila melanogaster (Fruit fly) Length = 441 Score = 135 bits (327), Expect = 2e-30 Identities = 59/145 (40%), Positives = 95/145 (65%), Gaps = 1/145 (0%) Query: 268 SDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIG 327 +D+ S++++P D S W + +W+ +PI++ L IP +YPL+FIMCI IG Sbjct: 230 ADVVPGSIYAYPRDA-SGWMQFWWIFVFPIKVTLSLLIPHPMKYRRLYPLSFIMCILCIG 288 Query: 328 SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGS 387 +YL+ W++T G ++VP + GLT LAAG+++PEAVSS++ + G +G+SNS+G+ Sbjct: 289 GNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGA 348 Query: 388 NTFDILLCLGLPWLVKSLFYPSTPE 412 N+ ILL LG+PW +K+ + T E Sbjct: 349 NSLAILLSLGVPWFIKNCIHYGTGE 373 Score = 113 bits (272), Expect = 8e-24 Identities = 48/104 (46%), Positives = 70/104 (67%) Query: 75 SDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMA 134 +D T Q + G+++LH F A+Y F+LL +C DYF+P +E ICE L+++ D+A ATFMA Sbjct: 70 ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAAATFMA 129 Query: 135 AASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 A+S PE F N + T + E D+G+G ++GS +FN L V AL Sbjct: 130 TATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173 >UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependent Na,Ca exchanger; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to K-dependent Na,Ca exchanger - Strongylocentrotus purpuratus Length = 259 Score = 130 bits (313), Expect = 9e-29 Identities = 52/127 (40%), Positives = 89/127 (70%), Gaps = 3/127 (2%) Query: 284 SFWKKLFWVLTWPIRLILWATIPDCRHR---HSIYPLTFIMCITWIGSVSYLVAWIITVV 340 S++ ++ W + P+ LI++ T+PDCR +Y TF + W+ ++Y++ W+I V+ Sbjct: 57 SWFFRVLWFVGLPVILIMFLTVPDCRKPGLWRRLYFFTFFISTVWLAGLAYVLYWMIVVI 116 Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 G TL++PD++ G+++LAAGTS+P+A++SVLV + G+G M +SN +GSN F++ +CLGL W Sbjct: 117 GYTLDIPDTVMGISLLAAGTSVPDAIASVLVARDGYGDMALSNIVGSNIFEVFICLGLLW 176 Query: 401 LVKSLFY 407 + L Y Sbjct: 177 FIYGLVY 183 >UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 346 Score = 128 bits (309), Expect = 3e-28 Identities = 63/165 (38%), Positives = 103/165 (62%), Gaps = 8/165 (4%) Query: 246 RSVQNGDLERGIEMTRRHDSTGSDISTS---SVWSFPGDKISFWKKLFWVLTWPIRLILW 302 RS + DLER +D+ D + + S + P ++ + ++ L +PI + + Sbjct: 108 RSDPHRDLERNDRRNTDNDNFVDDENETEPGSPFRLPEKGVNRYAQM---LAFPIIAVFF 164 Query: 303 ATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360 +IPDCR + Y LTFI + WIG ++Y++ W++T GDT+ +PD++ GLT+LAAG Sbjct: 165 ISIPDCRRKRWKRCYVLTFICSLLWIGFLTYILVWMVTAFGDTIGIPDTVMGLTLLAAGA 224 Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 S P+ + S++ + G+G M IS+SIGSN FDIL+ LGLPW ++++ Sbjct: 225 STPDTMLSIIAARGGYGDMAISHSIGSNLFDILVGLGLPWFIQTV 269 Score = 35.5 bits (78), Expect = 2.7 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 92 CF-LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTF 150 C+ L C LL V + + + I + G T +AA +S+P+ ++ + Sbjct: 178 CYVLTFICSLLWIGFLTYILVWMVTAFGDTIGIPDTVMGLTLLAAGASTPDTMLSIIAAR 237 Query: 151 VTEGDLGVGAVVGSAVFNVL 170 GD+ + +GS +F++L Sbjct: 238 GGYGDMAISHSIGSNLFDIL 257 >UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform 1; n=2; Ostreococcus|Rep: Solute carrier family 24 member 4, isoform 1 - Ostreococcus tauri Length = 545 Score = 126 bits (305), Expect = 8e-28 Identities = 60/154 (38%), Positives = 90/154 (58%), Gaps = 2/154 (1%) Query: 79 TRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASS 138 T + G ++ + +Y F+ + VC+D+FV ++E ICERL ++ D+AGATFMAA SS Sbjct: 57 TESWEKKGGLVAYFVGVVYLFIGIAIVCDDFFVASLEKICERLGLSDDVAGATFMAAGSS 116 Query: 139 SPELFINCVGTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCM 196 +PEL + + + D +GVG +VGSAVFN+L + +FAG ++LDW + RDC Sbjct: 117 APELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFAGETLKLDWRPLARDCT 176 Query: 197 MYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 Y + LT + W E L+ V +Y YI Sbjct: 177 FYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYI 210 Score = 102 bits (245), Expect = 2e-20 Identities = 50/119 (42%), Positives = 76/119 (63%), Gaps = 5/119 (4%) Query: 286 WKKL-FWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVS-YLVAWIITVVG 341 WKK WVL+ P +L T+P C + + Y ++F + + +IG +S Y+V W + G Sbjct: 352 WKKRPMWVLSLPWYTVLTFTVPPCHRKEWENWYIVSFCVSVAYIGVISHYMVEWCARI-G 410 Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 L++P + G T+LAAGTS+P+A+SS+ V + G M ++N++GSN FDI L LGLPW Sbjct: 411 CILSIPPVVMGTTVLAAGTSIPDALSSISVARDGFADMAVANAVGSNVFDIWLGLGLPW 469 Score = 41.5 bits (93), Expect = 0.041 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSV--LVTKQGHGTMGISNSIGSNTFDILLCLG 397 + L + D + G T +AAG+S PE +S L+ +G+ +GS F+IL+ +G Sbjct: 97 ERLGLSDDVAGATFMAAGSSAPELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIG 154 >UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodium-calcium potassium exchanger; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cone sodium-calcium potassium exchanger - Strongylocentrotus purpuratus Length = 651 Score = 121 bits (291), Expect = 4e-26 Identities = 56/123 (45%), Positives = 85/123 (69%), Gaps = 3/123 (2%) Query: 286 WKK-LFWVLTWPIRLILWATIPDCRHRHSI--YPLTFIMCITWIGSVSYLVAWIITVVGD 342 W+K + ++L P+ +L+ T+PD R S Y +TFI CI WI SYL+ W+ VGD Sbjct: 457 WRKQVTYILLAPLVYVLYFTLPDVRRVESRKWYSVTFIGCIFWIAGFSYLMVWMAKEVGD 516 Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 T+ + + + GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPW++ Sbjct: 517 TIGIEERVMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWIL 576 Query: 403 KSL 405 S+ Sbjct: 577 WSI 579 Score = 113 bits (272), Expect = 8e-24 Identities = 48/98 (48%), Positives = 71/98 (72%) Query: 73 FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132 +P D T Q++ G I+LH L +Y F+ L VC+++FVPA+ +I ++L+++ D+AGATF Sbjct: 107 YPRDLFTLQQKKDGAIVLHVILMIYMFVALAIVCDEFFVPALSVITDKLDLSDDVAGATF 166 Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 MAA S+PELF + +G F D+GVG +VGSAVFN+L Sbjct: 167 MAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204 Score = 42.7 bits (96), Expect = 0.018 Identities = 19/57 (33%), Positives = 33/57 (57%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 ++V+ D L++ D + G T +AAG S PE +S++ +G+ +GS F+IL Sbjct: 148 LSVITDKLDLSDDVAGATFMAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204 Score = 34.7 bits (76), Expect = 4.7 Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 8/118 (6%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177 + + I + G T +AA +S P+L + + GD+ V + VGS +F++ + +P Sbjct: 516 DTIGIEERVMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWI 575 Query: 178 LFA----GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL-VLMYTFYI 230 L++ GA + +D S C ++ +++ +L W ++ M+ FY+ Sbjct: 576 LWSISQNGASVSVD--SKGLFCSIFLLFGMLILVVILIAVNKWRMTKIMGGCMFLFYL 631 >UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 231 Score = 112 bits (269), Expect = 2e-23 Identities = 47/96 (48%), Positives = 70/96 (72%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131 E+P D T QR+ G ++LH F +Y F+ L VC+++FVPA+ +I E+L I+ D+AGAT Sbjct: 116 EYPEDLFTLEQRRQGAVVLHMFGMMYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 175 Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 FMAA S+PELF + +G F++ ++G+G +VGSAVF Sbjct: 176 FMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211 Score = 44.8 bits (101), Expect = 0.004 Identities = 20/54 (37%), Positives = 30/54 (55%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390 +TV+ + L + D + G T +AAG S PE +SV+ H +GI +GS F Sbjct: 158 LTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211 >UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger - Nasonia vitripennis Length = 418 Score = 107 bits (258), Expect = 4e-22 Identities = 47/97 (48%), Positives = 68/97 (70%), Gaps = 1/97 (1%) Query: 315 YPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374 + +TFI I WI + SYL+ W VVGDT+ +P + GLT LAAGTS+P+ ++SV+V ++ Sbjct: 259 FAVTFIGSILWIAAYSYLMVWWANVVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARK 318 Query: 375 GHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTP 411 G G M +S+S+GSN FD+ + L +PWL+ L Y TP Sbjct: 319 GFGDMAVSSSVGSNIFDVTVGLPVPWLLYGLIY-GTP 354 Score = 38.3 bits (85), Expect = 0.38 Identities = 17/54 (31%), Positives = 32/54 (59%) Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 ++ + + I ++ G TF+AA +S P+L + + GD+ V + VGS +F+V Sbjct: 283 VVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDV 336 >UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061-PB.3 - Drosophila melanogaster (Fruit fly) Length = 110 Score = 104 bits (249), Expect = 5e-21 Identities = 46/94 (48%), Positives = 62/94 (65%), Gaps = 1/94 (1%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L + D+AGATF+AA++S+PELF+N VGTFVT GD+G+G +VGS+VFN+L + C +F Sbjct: 17 LRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT 76 Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214 +LDWW VTRD Y L L D + Sbjct: 77 QPT-KLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109 Score = 41.9 bits (94), Expect = 0.031 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 4/79 (5%) Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 G+ L + + G T LAA TS PE + + T +G +G+ +GS+ F+IL+ G+ Sbjct: 14 GNALRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCG 73 Query: 401 L----VKSLFYPSTPENHW 415 + K ++P T + W Sbjct: 74 IFTQPTKLDWWPVTRDTAW 92 >UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antiporter; n=1; Pirellula sp.|Rep: Probable sodium/calcium exchanger antiporter - Rhodopirellula baltica Length = 432 Score = 83.0 bits (196), Expect = 1e-14 Identities = 82/343 (23%), Positives = 145/343 (42%), Gaps = 35/343 (10%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 G ++ + L C L++ C+ + + A E I N++ + G T A +SS PELF Sbjct: 2 GIVIPLVLIFLTC-LVIWRACDGFEI-ASEYIGR--NLSEGVRGGTINAISSSIPELFTT 57 Query: 146 CVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL-FAGAVI--------ELDWWSVT 192 + FV +G+G GSA+FN + +PA C L G V+ + + Sbjct: 58 LIALFVLSDRDGFSIGIGTTAGSALFNGMIIPAVCILSVVGFVVMGVRVTSVNVSTRVLL 117 Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGD 252 RD + LIL + ++++W + L+L+LMY Y++ + + +S+ + D Sbjct: 118 RDGISLILCEFILILLINGEQLHWWQGLILMLMYATYLVYMLTTMKSSELSANDEQPDND 177 Query: 253 LERGIEMTRR------HDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIP 306 E E R + +G + W K+ W W + L I Sbjct: 178 GEEEDESPRGPLASLFYWISGGPLLDLERWFVKDHHREQMKEETW-NGWGLLLTSTGVI- 235 Query: 307 DCRHRHSIYPLTFIMCITWIGS-VSYLVAWIITVVGDT---LNVPDSITGLTILAAGTSL 362 ++ T ++ W+GS + + + G T L +P + + TS+ Sbjct: 236 ------AMACWTLVLACEWLGSGPANVENPSYELFGQTFEGLGMPAMFVAVIFASMATSV 289 Query: 363 PEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 P+ V S+ + G ++N++GSN FDI LG P + +L Sbjct: 290 PDTVMSIRDARDGDYDDAVANALGSNIFDICFALGFPLFLYTL 332 >UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-dependent sodium-calcium exchanger NCKX1; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to potassium-dependent sodium-calcium exchanger NCKX1 - Ornithorhynchus anatinus Length = 543 Score = 82.6 bits (195), Expect = 2e-14 Identities = 37/81 (45%), Positives = 58/81 (71%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 + + S+LV VG+T+ + + I GL+ILAAGTS+P+ ++SV+V ++G G M +S+S+ Sbjct: 392 VWAFSFLVFLWAAQVGETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSSSV 451 Query: 386 GSNTFDILLCLGLPWLVKSLF 406 GSN FDI + L +PW + SLF Sbjct: 452 GSNIFDITVGLPVPWFLYSLF 472 Score = 47.6 bits (108), Expect = 6e-04 Identities = 20/50 (40%), Positives = 32/50 (64%) Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121 E+P D + +R+ G++LLH Y F+ L VC++YFVPA+ +I +L Sbjct: 87 EYPEDVFSVEERRRGWVLLHVSGMAYVFVALAIVCDEYFVPALGVITAKL 136 Score = 46.0 bits (104), Expect = 0.002 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 176 CALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILE-KI 234 CAL + ++ L WW + RD Y LI D + W E+LLL+ Y Y+ K Sbjct: 144 CALCSREILRLTWWPLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKW 203 Query: 235 N-PLDA 239 N PL+A Sbjct: 204 NRPLEA 209 Score = 35.9 bits (79), Expect = 2.0 Identities = 16/51 (31%), Positives = 30/51 (58%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 E + I+ +I G + +AA +S P+L + + GD+ V + VGS +F++ Sbjct: 408 ETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 458 >UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_128, whole genome shotgun sequence - Paramecium tetraurelia Length = 378 Score = 77.8 bits (183), Expect = 5e-13 Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 19/323 (5%) Query: 95 ALYCFLLLGS--VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 AL+ ++L G + DY +P +E + + ++ S+ MA S PEL N + F + Sbjct: 6 ALFFYVLSGQTYLSNDYLMPCLESLSTKWHL-SETGTGILMALGMSIPELTTNILSCFKS 64 Query: 153 EG-DLGVGAVVGSAVFNVLAVPACCALFAG----AVIELDWWSVTRDCMMYXXXXXXLIL 207 G GA+VGS VF+ +LF+ + ++ ++ RD +Y L Sbjct: 65 SRIGYGFGAIVGSGVFDFTVCFGLMSLFSNYYHKRALRMNLKALMRDIYVYLLTLLFLTF 124 Query: 208 TLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTG 267 D +I EAL+L L Y Y+L + ++ S Q ++ H Sbjct: 125 VFWDYEISLTEALILTLFYPSYLLYSLVQMEQKDDF-QLSHQKHHFPTLLQFLDFHPEQA 183 Query: 268 SDISTSSV---WSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCIT 324 D+ +++ ++ +L P L+ TIP +H + + C Sbjct: 184 EDLDVDGKEIGQENQQEQVQEEQQPSKILL-PFTLLFKFTIP--KHPELAFIIISFYCFL 240 Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384 + +V + + +V + GLTI + G ++ + +++ L K + S+ Sbjct: 241 TVNVTMTVVDEFV----EQFSVSPAFVGLTIASWGGNIQDILNASLAAKNKKTELATSSI 296 Query: 385 IGSNTFDILLCLGLPWLVKSLFY 407 IGS ++ +CLG PW++ L + Sbjct: 297 IGSQIMNLQICLGFPWVLTMLIW 319 >UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium difficile|Rep: Ca2+/Na+ antiporter - Clostridium difficile (strain 630) Length = 331 Score = 70.5 bits (165), Expect = 8e-11 Identities = 79/307 (25%), Positives = 134/307 (43%), Gaps = 45/307 (14%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 FI + FL + + G+ D F+ I ++ NI+ I GAT ++ A++ PE ++ Sbjct: 2 FITVVLFLVGFLLITKGA---DIFINCTVEIGKKTNISEIILGATIVSFATTLPEFTVSL 58 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 + + + +G VGS + N + +F +D ++ LI Sbjct: 59 LASIDGHTTMSLGNAVGSIICNT-GLALGLVVFISP-FNVDKKMFFSKSLLLIVSVIVLI 116 Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDST 266 L LD I ++LLL+++ FY++ + R+++N +T Sbjct: 117 LLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKNRNIKN--------------NT 162 Query: 267 GSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWI 326 DIST ++ G F VL L+L+AT IM I I Sbjct: 163 IKDISTKKGKNYRG---------FSVLEIVKILLLFAT-------------GLIMMI--I 198 Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386 GS + + +I + LN+P I LTI+A GTSLPE VSS+ ++ H + + N +G Sbjct: 199 GSQILIESGVI--IASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILG 256 Query: 387 SNTFDIL 393 +N +I+ Sbjct: 257 ANILNIV 263 Score = 47.6 bits (108), Expect = 6e-04 Identities = 23/59 (38%), Positives = 35/59 (59%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 +G N+ + I G TI++ T+LPE S+L + GH TM + N++GS + L LGL Sbjct: 29 IGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGL 87 Score = 38.3 bits (85), Expect = 0.38 Identities = 35/148 (23%), Positives = 62/148 (41%), Gaps = 4/148 (2%) Query: 86 GFILLHCFLALYCF---LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPEL 142 GF +L L F L++ + + + II LNI I T +A +S PE+ Sbjct: 176 GFSVLEIVKILLLFATGLIMMIIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEI 235 Query: 143 FINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXX 202 + ++ VG ++G+ + N+++V A A+ I L M Sbjct: 236 VSSITAIRKNHHEISVGNILGANILNIVSVIAVSAIPNNIPI-LSQNRQLDIPFMILLLL 294 Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFYI 230 +I TL +K+ + +L++ Y YI Sbjct: 295 IVIIPTLKSNKLSRIQGILMLFTYFLYI 322 >UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family transporter: sodium ion/calcium ion - Ostreococcus lucimarinus CCE9901 Length = 603 Score = 70.1 bits (164), Expect = 1e-10 Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG----T 149 LAL F L SV E +FVPA+ I L + D+AGAT ++ + +P++F Sbjct: 95 LALTLFAALASVAERFFVPALRNIARGLALRDDVAGATLLSFGNGAPDIFAQIAALSHED 154 Query: 150 FVTEGDLGVGAVVGSAVFNVLAVPACCALFA-----GAVIELDWWSVTRDCMMYXXXXXX 204 L VGAV G+ F V C L A G + LD W+ RD Y Sbjct: 155 VAESAALAVGAVTGAGAFIASFVFPCVVLIATRAASGRGLVLDKWNFGRDVGFYAVASAM 214 Query: 205 LILTLLDDKIYWHEALLLVLMYTFYI 230 + LD ++ +EA L +Y Y+ Sbjct: 215 ALGFFLDGRVEAYEAAALFSLYAAYL 240 Score = 44.0 bits (99), Expect = 0.008 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 302 WATIPDCRH-RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360 W+ I D R + + F I W+ + + + +++ +G V +++ G T+LA G Sbjct: 422 WSHIGDVASIRALLVAVAFFQSILWMNTAASELVSLLSAIGKVTGVSEALLGATVLAWGN 481 Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394 S+ + VS+ +V + G+ M I+ ++L+ Sbjct: 482 SVGDFVSNTVVARAGNPNMAIAACFAGPLMNLLV 515 >UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1117 Score = 69.7 bits (163), Expect = 1e-10 Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 5/188 (2%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 +LL L+ F +G V D+F P + I RL + AG TF+A + SP++F Sbjct: 181 LLLILMWMLFLFSWVGVVASDFFCPNLSTIASRLGLNESTAGVTFLAFGNGSPDVFSTFG 240 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207 G L +G ++G+A F V + L A +++ W RD + + Sbjct: 241 AMKTDSGSLAIGELLGAASFIVSVISGSMMLI--APFKVNAWPFCRDVGFFTVAVALTLT 298 Query: 208 TLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTG 267 L D K+ E + L+ +Y Y I S R Q LE E RH Sbjct: 299 FLFDGKLRRIETIALICLYLLYATTVI---IGSWWQERRRKQKRRLEVAREEYDRHADDR 355 Query: 268 SDISTSSV 275 S +S S+ Sbjct: 356 SILSRGSI 363 Score = 54.8 bits (126), Expect = 4e-06 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F + + WI ++ V I+ VG + + D+I GLT+ A G SL + V+++ + K GH Sbjct: 950 FTVSVMWIMTIVDEVVSILQTVGIIVGLSDAILGLTVFAVGNSLGDLVANITIAKLGHPV 1009 Query: 379 MGISNSIGSNTFDILLCLGL--PWLV 402 M IS ++LL +G+ WL+ Sbjct: 1010 MAISACFAGPMLNLLLGIGISGTWLL 1035 >UniRef50_UPI000023E8AF Cluster: hypothetical protein FG08070.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG08070.1 - Gibberella zeae PH-1 Length = 389 Score = 68.9 bits (161), Expect = 2e-10 Identities = 70/301 (23%), Positives = 122/301 (40%), Gaps = 16/301 (5%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV I+ R I + + A + EL + L VG ++GSA+ Sbjct: 26 DKFVDHTAIVAHRTGIPDTVIA--LLTAGAEWEELVVVIASLAQGRPSLAVGNIIGSAIS 83 Query: 168 NVLAVPACCALFA--GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEA-LLLVL 224 N+L + LF G+ + D S + +T +I W +L+ Sbjct: 84 NILGAFSLGLLFRPKGSHVTFDRSSRIYSLFLLIITTFVTPITYFSHRIIWLICGSILIA 143 Query: 225 MYTFYILE-----KINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFP 279 ++ Y++ L A + S + IE TR + +I S P Sbjct: 144 LFAIYLISIGWAISRGSLTAPEGSDDDSSDDESDTSSIESTRSINRRRHEIQASQEEREP 203 Query: 280 GDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSI-YPLTFIMC-ITWIGSVSYLVAWII 337 ++ +L + ++ + R R S+ Y + F+M I Y++A Sbjct: 204 ENR----NELDQRVGGSAEGVVVTNVSSRRRRRSLGYHIGFLMLGFLAICLAGYVLAHAA 259 Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + D + + D + G+ ILA T+LPE +VL +GH + ++N++GSN F + LCLG Sbjct: 260 INITDAIGISDVLFGIIILAIATTLPEKFVAVLSGNRGHIGILVANTVGSNVFLLSLCLG 319 Query: 398 L 398 + Sbjct: 320 I 320 >UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 433 Score = 68.5 bits (160), Expect = 3e-10 Identities = 39/153 (25%), Positives = 73/153 (47%), Gaps = 2/153 (1%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L+ F++LG +DYF P++ +I + L ++ ++AG TF+A + +P++F + + Sbjct: 41 LMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIF-SAIAAVSAH 99 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 A +G+ +F V L G L+ TRD + Y + +T+ + Sbjct: 100 SKNPNAAQLGAGIFVTTVVVGSVTLCTGG-FHLNNRPFTRDVLFYLGAVSWMFITMYRQR 158 Query: 214 IYWHEALLLVLMYTFYILEKINPLDASQRMTPR 246 I EA+ ++ Y Y++ I +QR R Sbjct: 159 ITMLEAIGFIIFYFAYVVVVIVGRYVNQRWKRR 191 Score = 43.6 bits (98), Expect = 0.010 Identities = 24/78 (30%), Positives = 37/78 (47%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L FI+ + WI + + I+ G L + ++I GLT LA G S+ + V+ + +QG Sbjct: 355 LAFIVSVVWIYVTANEIVNILQSFGIVLGLSNAILGLTFLAWGNSIGDLVADTTMARQGF 414 Query: 377 GTMGISNSIGSNTFDILL 394 M G ILL Sbjct: 415 PNMATGACFGGPMLSILL 432 >UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep: Predicted protein - Aspergillus oryzae Length = 363 Score = 67.7 bits (158), Expect = 5e-10 Identities = 68/298 (22%), Positives = 126/298 (42%), Gaps = 28/298 (9%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D F+ II +RL ++ + + A + EL + + L +G V+GS + Sbjct: 25 DKFIDHTVIIGQRLGVSQTLIAV--LTAGAEYEELAVVVAAVLQKQSPLALGNVMGSTIS 82 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD--DKIYWHEALLLVLM 225 N+L + L I D + ++ ILT + +KI + + LM Sbjct: 83 NILGAFSLGLLLHPGPIAFDQSAKVYTALLLSITTAFYILTYFNMLNKITGGVLVAIFLM 142 Query: 226 Y---TFYILEK--INPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPG 280 Y T Y + K + P +AS + D E +R DS D S +S Sbjct: 143 YIICTCYAIHKGAMEPPEASDSDSDSDDDASDDEHSYSTSRPQDSRVQDESETSP----- 197 Query: 281 DKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVV 340 +LT L+ + P H + ++ +T G YL++ +V+ Sbjct: 198 -----------LLTHEEALVAKKSAPRSLFYHISQLVMGLLTLTISG---YLLSRSASVI 243 Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 D ++ ++ GLT+++ T+LPE + +++ +GH + ++++ GSN F + LC G+ Sbjct: 244 ADCFHLSGTVVGLTVVSFATTLPEKMVAIISGSRGHSGIVVASTAGSNIFLLTLCAGV 301 >UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus kandleri Length = 329 Score = 67.7 bits (158), Expect = 5e-10 Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%) Query: 67 PAAILEFPSDGLTRFQRQHGF-ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIAS 125 P ++ P G R +++ CF+ + FL + V A + + ++ Sbjct: 6 PCSVRALPVRGSDRVDPWSALAVMMGCFVGFH-FL------SELLVDATVGLARKYGLSE 58 Query: 126 DIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 +AGAT A +S+PE + + ++GVG ++GSAV+NV +P AL AG + Sbjct: 59 SVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAGG-LT 117 Query: 186 LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 L+ RD + Y ++++L D + EAL V +Y Y+L Sbjct: 118 LERAVYRRDVLFYLLALVVVLVSLWDRVVLRVEALAWVALYGLYVL 163 Score = 63.7 bits (148), Expect = 9e-09 Identities = 28/79 (35%), Positives = 51/79 (64%) Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380 + + I ++S L+ + + +S L + AAGTS+P+ ++SV ++G G++ Sbjct: 193 VAVVGIAALSDLMVRATVDFCEGFGLSESRVSLLLNAAGTSVPDTLASVHAARRGFGSLA 252 Query: 381 ISNSIGSNTFDILLCLGLP 399 +SN++GSNTFD+L+CLG+P Sbjct: 253 VSNAVGSNTFDLLVCLGVP 271 Score = 35.9 bits (79), Expect = 2.0 Identities = 17/51 (33%), Positives = 28/51 (54%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 +S+ G T+ A GTS PE SS+ H +G+ +GS +++ + GL Sbjct: 58 ESVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGL 108 >UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr8 scaffold_150, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 593 Score = 67.3 bits (157), Expect = 7e-10 Identities = 40/147 (27%), Positives = 78/147 (53%), Gaps = 3/147 (2%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 G+ +L +LA+ F LLG+ +YF ++E + L ++ IAG T ++ + + ++F + Sbjct: 110 GYTVLLLWLAVL-FYLLGNTAANYFCSSLENLSRVLKLSPTIAGVTLLSLGNGAADVFAS 168 Query: 146 CVG-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXX 203 V T ++GD+G+ V+G A F V ++F G I +D S RD + + Sbjct: 169 IVSFTRTSDGDVGLNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFFLIALA 228 Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI 230 L++ ++ K+ + ++ V +Y FY+ Sbjct: 229 SLLVIIIIGKVSFWGSVCFVSIYFFYV 255 Score = 41.5 bits (93), Expect = 0.041 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 3/83 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--H 376 F+M +TW ++ + ++ G+ L + ++ GLT+LA G SL + +++V + G Sbjct: 435 FLMSVTWTYIIAEELVSLLVSFGNILGISPAVLGLTVLAWGNSLGDLIANVALAANGGQD 494 Query: 377 GT-MGISNSIGSNTFDILLCLGL 398 G + +S F+ L+ LGL Sbjct: 495 GVQIAVSGCYAGAMFNTLVGLGL 517 >UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3; n=2; Caenorhabditis|Rep: Putative uncharacterized protein ncx-3 - Caenorhabditis elegans Length = 807 Score = 67.3 bits (157), Expect = 7e-10 Identities = 32/100 (32%), Positives = 60/100 (60%), Gaps = 2/100 (2%) Query: 315 YPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374 YP F++ + IG V+ +V + ++ G + + D++T +T++A GTSLP+ +S + + Sbjct: 634 YPC-FVVALIGIGLVTAVVGDVASIFGCMVGLKDAVTAITLVALGTSLPDTFASKIAAES 692 Query: 375 GH-GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413 + N GSN+ ++ L LGLPW++ SL++ S E+ Sbjct: 693 DDTADNAVGNVTGSNSVNVFLGLGLPWVIASLYWASKGES 732 Score = 51.2 bits (117), Expect = 5e-05 Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 15/152 (9%) Query: 127 IAGATFMAAASSSPELF---INCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183 +A T MA SS+PE+ I VG GDLG G +VGSA FN+ + A C G Sbjct: 92 VANLTLMALGSSAPEILLSIIEIVGNGFKAGDLGPGTIVGSAAFNLFCISAICVFAVGTQ 151 Query: 184 ---IEL-DWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYILEKINPL 237 IEL + VT + L+L ++ + W EA+L +L + ++ Sbjct: 152 TKRIELYRVFVVTAFFGTFAYIWVFLVLIVITPNVVDVW-EAILTLLFFIILVVVSY--- 207 Query: 238 DASQRMTPRSVQNGDLERGIEMTRRHDSTGSD 269 A + ++ DL+ +EM +HD D Sbjct: 208 -AVDAQIWKKKKSSDLQEELEMA-QHDGKVDD 237 >UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein - Halobacterium salinarium (Halobacterium halobium) Length = 344 Score = 66.1 bits (154), Expect = 2e-09 Identities = 29/71 (40%), Positives = 46/71 (64%) Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 L+ +T + T ++P + G+TILAA TSLP+A+ SV + GHG + N +GSNTFD Sbjct: 207 LLVGAVTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLGSNTFD 266 Query: 392 ILLCLGLPWLV 402 +L+ + + L+ Sbjct: 267 LLVAIPIGVLI 277 Score = 51.2 bits (117), Expect = 5e-05 Identities = 31/103 (30%), Positives = 46/103 (44%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 A E + + + + G+ +A SS PEL V LGVGA+VGSA+FN+L V Sbjct: 35 AAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVGAIVGSAIFNILVV 94 Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215 P + ++ V ++ Y L+LT IY Sbjct: 95 PGLAGITTTQPLDATRTVVYKEAQFYMLAVSTLLLTFALAVIY 137 Score = 39.9 bits (89), Expect = 0.13 Identities = 24/78 (30%), Positives = 38/78 (48%) Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163 SV + V A+ + +I S +AG T +AAA+S P+ ++ G +G V+G Sbjct: 202 SVAVELLVGAVTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLG 261 Query: 164 SAVFNVLAVPACCALFAG 181 S F++L L AG Sbjct: 262 SNTFDLLVAIPIGVLIAG 279 Score = 37.1 bits (82), Expect = 0.88 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGIS 382 + W GS S+L A + +P + G ++A G+S PE +S ++ G +G+ Sbjct: 24 LIWAGS-SWLEA-AAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVG 81 Query: 383 NSIGSNTFDILLCLGL 398 +GS F+IL+ GL Sbjct: 82 AIVGSAIFNILVVPGL 97 >UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter - Mariprofundus ferrooxydans PV-1 Length = 322 Score = 65.7 bits (153), Expect = 2e-09 Identities = 34/86 (39%), Positives = 50/86 (58%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F++ + + S +V W + L V D I GLTI+A GTSLPE V+S++ +G Sbjct: 174 LWFVVGLALLIISSRMVVWGAVEIAHLLGVSDLIIGLTIVAIGTSLPELVASLVSALKGE 233 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLV 402 + I N IGSN F++L L +P L+ Sbjct: 234 ADLAIGNVIGSNMFNLLAVLAMPALI 259 Score = 55.6 bits (128), Expect = 2e-06 Identities = 28/63 (44%), Positives = 38/63 (60%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 V L VP + GLTI++ GTSLPE + S + G+ +GI N +GSN +I L LG+ Sbjct: 29 VAKNLRVPPMVIGLTIVSLGTSLPEMIVSAMAALDGNRDLGIGNVLGSNIANIGLVLGIT 88 Query: 400 WLV 402 LV Sbjct: 89 ALV 91 Score = 48.0 bits (109), Expect = 5e-04 Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 A+EI L ++ I G T +A +S PEL + V E DL +G V+GS +FN+LAV Sbjct: 194 AVEI-AHLLGVSDLIIGLTIVAIGTSLPELVASLVSALKGEADLAIGNVIGSNMFNLLAV 252 Query: 173 PACCAL 178 A AL Sbjct: 253 LAMPAL 258 Score = 40.7 bits (91), Expect = 0.072 Identities = 20/71 (28%), Positives = 35/71 (49%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + + L + + G T ++ +S PE+ ++ + DLG+G V+GS + Sbjct: 20 DRFVDGAASVAKNLRVPPMVIGLTIVSLGTSLPEMIVSAMAALDGNRDLGIGNVLGSNIA 79 Query: 168 NVLAVPACCAL 178 N+ V AL Sbjct: 80 NIGLVLGITAL 90 >UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep: F15I1.21 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 644 Score = 65.3 bits (152), Expect = 3e-09 Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 5/147 (3%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 G+ILL +L F LLG+ DYF ++E + + L + +AG T + + +P++F + Sbjct: 136 GYILLGVWLVAL-FYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS 194 Query: 146 CVGTFV--TEGDLGVGAVVGSAVFNVLAVPACCAL-FAGAVIELDWWSVTRDCMMYXXXX 202 + FV +G++G+ +V+G AVF V +L A +++D RD + Sbjct: 195 -IAAFVGSDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTL 253 Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFY 229 L++ L+ K+ A+ V +Y FY Sbjct: 254 VALMVILMVGKVTVGIAIAFVSIYVFY 280 Score = 42.7 bits (96), Expect = 0.018 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHG- 377 FIM I W ++ + ++ G + SI GLT+LA G S+ + VS++ ++ G Sbjct: 485 FIMSIVWFYMIANELVALLVTFGGIYGINPSILGLTVLAWGNSMGDLVSNIALSMNGGDG 544 Query: 378 -TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418 + +S F+ L+ LG+ + + + +PE + + + Sbjct: 545 VQIALSGCYAGPMFNTLVGLGMSMFLGA--WSKSPETYMIPE 584 >UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr7 scaffold_42, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 560 Score = 65.3 bits (152), Expect = 3e-09 Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 6/129 (4%) Query: 281 DKISFW-KKLFW-VLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIIT 338 D I W ++FW +L P R L+A +P H + FI + +I ++Y+V + Sbjct: 356 DNIYLWVARIFWQLLLLPWRF-LFAFVPPPHIAHGWF--AFICSLIFISGIAYIVTKLTD 412 Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLG 397 ++ T + + T LAAGTS P+ V+S + +Q I+N I SN+ +I + +G Sbjct: 413 LISCTSGINSYVIAFTALAAGTSWPDLVASKIAAERQTTADSAIANIICSNSVNIYMGIG 472 Query: 398 LPWLVKSLF 406 +PWL+ + + Sbjct: 473 IPWLINTTY 481 >UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; Methanosarcinaceae|Rep: Sodium/calcium exchanger protein - Methanosarcina acetivorans Length = 350 Score = 65.3 bits (152), Expect = 3e-09 Identities = 35/89 (39%), Positives = 50/89 (56%), Gaps = 5/89 (5%) Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 + C + Y V I + L +PD++ G T++A GTSLPE V +V +QG+G++ Sbjct: 213 LSCAAIVIGAKYFVEESI-FFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQGYGSI 271 Query: 380 GISNSIGSNTFDILLCLGLPWLVKSLFYP 408 + N IGSN +I L LGL LFYP Sbjct: 272 ALGNVIGSNITNIFLILGL----SGLFYP 296 Score = 54.0 bits (124), Expect = 7e-06 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158 FL+ GS DYFV + I ++L ++ + G T +A +S PEL + + + + Sbjct: 15 FLVKGS---DYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVI 71 Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218 G VVGS + NV + AL + E+D + RD + + + ++ E Sbjct: 72 GNVVGSNIANVGLIVGVAALLSPMKTEID--MLKRDGYIMLFSAVLFFVFAFNRELSMLE 129 Query: 219 ALLLVLMYTFYI 230 A L VL+Y Y+ Sbjct: 130 AGLFVLLYIAYV 141 Score = 45.2 bits (102), Expect = 0.003 Identities = 22/68 (32%), Positives = 39/68 (57%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + + L V + + GLT++A GTS+PE SS+ + Q + I N +GSN ++ L +G Sbjct: 28 STIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVIGNVVGSNIANVGLIVG 87 Query: 398 LPWLVKSL 405 + L+ + Sbjct: 88 VAALLSPM 95 Score = 43.2 bits (97), Expect = 0.013 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 YFV E L I + G T +A +S PEL + G + +G V+GS + N Sbjct: 224 YFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQGYGSIALGNVIGSNITN 283 Query: 169 VLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 + + LF +V E+ + T +M LI +I E ++L++ Y Sbjct: 284 IFLILGLSGLFYPLSVAEMSLFFTTP--VMIAISLILLIFISTGWEIKRWEGVVLMMFYV 341 Query: 228 FYIL 231 +++ Sbjct: 342 AFLV 345 >UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Firmicutes|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Clostridium perfringens (strain SM101 / Type A) Length = 331 Score = 64.5 bits (150), Expect = 5e-09 Identities = 35/79 (44%), Positives = 48/79 (60%), Gaps = 4/79 (5%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + + + GLTI+A GTSLPE V+S++ K+G + + N +GSNTF+ILL LGL Sbjct: 213 LGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFNILLILGL----S 268 Query: 404 SLFYPSTPENHWVTDLYFI 422 SL P T DL F+ Sbjct: 269 SLISPITIAASLSVDLIFL 287 Score = 54.0 bits (124), Expect = 7e-06 Identities = 51/190 (26%), Positives = 88/190 (46%), Gaps = 13/190 (6%) Query: 97 YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 Y FL++G + D FV I ++L + + I G T ++ +S+PEL ++ Sbjct: 3 YIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISAALKG 62 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL-----DW-WSVTRDCMMYXXXXXXLI 206 D+ +G V+GS +FN+LA C A+ A VI+ D+ ++ ++Y LI Sbjct: 63 SNDITMGNVLGSNLFNLLAALGCTAIVAPLVIKKHIIKNDFIVNLLATFVLYVFTFTGLI 122 Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMT-RRHDS 265 + + + + L+LVLM YI+ I + S + + E E + +S Sbjct: 123 GS--KNSLSRMDGLVLVLMCITYIIYLIYTVKRSHKKEDEVAVTVEFEDFEEKNIKSPNS 180 Query: 266 TGSDISTSSV 275 TG +I S V Sbjct: 181 TGKNILLSIV 190 Score = 49.2 bits (112), Expect = 2e-04 Identities = 25/66 (37%), Positives = 36/66 (54%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + L VP I GLTI++ GTS PE S+ +G + + N +GSN F++L LG Sbjct: 27 IAKKLGVPAVIIGLTIVSLGTSAPELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCT 86 Query: 400 WLVKSL 405 +V L Sbjct: 87 AIVAPL 92 Score = 40.3 bits (90), Expect = 0.095 Identities = 21/74 (28%), Positives = 36/74 (48%) Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 V + I L ++ + G T +A +S PEL + V E D+ +G ++GS FN+L Sbjct: 203 VDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFNIL 262 Query: 171 AVPACCALFAGAVI 184 + +L + I Sbjct: 263 LILGLSSLISPITI 276 >UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related family protein; n=1; Dichelobacter nodosus VCS1703A|Rep: K+-dependent Na+-Ca+ exchanger related family protein - Dichelobacter nodosus (strain VCS1703A) Length = 325 Score = 64.5 bits (150), Expect = 5e-09 Identities = 29/73 (39%), Positives = 43/73 (58%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S ++ W + LN+ D I GLTI+A GTSLPE SS++ ++ M + N +GSN Sbjct: 187 SRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNI 246 Query: 390 FDILLCLGLPWLV 402 F+ L +GL L+ Sbjct: 247 FNALAVVGLSGLI 259 Score = 47.2 bits (107), Expect = 8e-04 Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 8/119 (6%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + LNI+ I G T +A +S PEL + V + D+ +G +VGS +FN LAV Sbjct: 197 IAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNIFNALAVVGLS 256 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLL------DDKIYWHEALLLVLMYTFY 229 L E + +TRD ++ L + L + ++ L+L+++Y Y Sbjct: 257 GLITPFAAEPE--ILTRDLVVMTIVTAVLFVMGLIRRRDHNAELKLAHGLILLIIYLLY 313 Score = 38.7 bits (86), Expect = 0.29 Identities = 19/59 (32%), Positives = 31/59 (52%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408 + G+ I+ GTS PE + SV + + + N+ GSN +I L LG+ L+ + P Sbjct: 41 VIGIVIIGFGTSAPEMIVSVTAALNHNSGIALGNAYGSNIVNIGLILGISALIAPIPMP 99 Score = 35.9 bits (79), Expect = 2.0 Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 2/132 (1%) Query: 95 ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 A+ L+L D+FV + + ++ + G + +S+PE+ ++ Sbjct: 9 AIIIGLILLVKSADWFVDGAAALAKIAGLSPLVIGIVIIGFGTSAPEMIVSVTAALNHNS 68 Query: 155 DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214 + +G GS + N+ + AL A I + V+ + + L L DD I Sbjct: 69 GIALGNAYGSNIVNIGLILGISALI--APIPMPKKLVSGELFILLLITLLCFLWLQDDYI 126 Query: 215 YWHEALLLVLMY 226 EAL++++++ Sbjct: 127 SRSEALVMLVLF 138 >UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6; Trichocomaceae|Rep: Sodium/calcium exchanger protein - Aspergillus clavatus Length = 994 Score = 64.5 bits (150), Expect = 5e-09 Identities = 32/89 (35%), Positives = 51/89 (57%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F++ I WI +++ V ++ VG LN+ DS+ GLT+ A G SL + V+ + V + G+ Sbjct: 833 LGFVVAIFWIATIATEVVSLLKTVGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 892 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSL 405 M +S G +ILL +GL L +L Sbjct: 893 PVMALSACFGGPMLNILLGIGLGGLYMTL 921 Score = 54.4 bits (125), Expect = 5e-06 Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 3/145 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 FI+L +L+L F +G D+ + + L ++ + G TF+A + SP++F Sbjct: 114 FIILILWLSLL-FSTIGIAASDFLCIDLSTLASILGMSESLTGVTFLAFGNGSPDVFSTF 172 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 G L +G ++G+A F V AL ++ S RD + + Sbjct: 173 AAMRSNSGSLAIGELLGAASFITSVVAGSMALV--QPFKVARRSFVRDVGYFVIAVSFSM 230 Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231 + L D +++ E+ +V +Y FY++ Sbjct: 231 VLLADGRLHVWESAAMVGLYCFYVV 255 Score = 39.5 bits (88), Expect = 0.17 Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 8/96 (8%) Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367 PL FI+ I W+ + S + ++ + L + +S+TG+T LA G P+ S Sbjct: 111 PLAFIILILWLSLLFSTIGIAASDFLCIDLSTLASILGMSESLTGVTFLAFGNGSPDVFS 170 Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + G++ I +G+ +F + G LV+ Sbjct: 171 TFAAMRSNSGSLAIGELLGAASFITSVVAGSMALVQ 206 >UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7 precursor (Na(+)/Ca(2+)-exchange protein 7); n=2; Caenorhabditis|Rep: Putative sodium/calcium exchanger 7 precursor (Na(+)/Ca(2+)-exchange protein 7) - Caenorhabditis elegans Length = 672 Score = 64.5 bits (150), Expect = 5e-09 Identities = 32/87 (36%), Positives = 51/87 (58%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FIM I WI +S V ++T++G V + GLTILA S+ + ++ V V KQG+ Sbjct: 518 FIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPR 577 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405 M ++ +IG F++L+ GLP+ + L Sbjct: 578 MAMAAAIGGPLFNLLMGFGLPFTIAKL 604 Score = 55.6 bits (128), Expect = 2e-06 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---I 144 I++ L F+++ S +D+F P+I I L I+ +AG TFMA + +P++F Sbjct: 91 IIVGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIA 150 Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204 + + + + DL +G + G +F V + L + +E+ +S RD + Y Sbjct: 151 SVLSSPTPKADLALGELFGGGLFVTTMVVSTIILTSPFDVEV--FSTIRDLLFYLVALSF 208 Query: 205 LILT-LLDDKIYWHEALLLVLMYTFYILEKI 234 L + +++ L + +Y Y++ I Sbjct: 209 LAFCFVFYNRVTLWMPLTFLGLYLLYVITVI 239 >UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep: CG5685-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 950 Score = 64.1 bits (149), Expect = 7e-09 Identities = 29/94 (30%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 +TF++ I IG ++ ++ + G LN+ DS+T + +A GTS+P+ +S++ K Sbjct: 779 VTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDE 838 Query: 377 GTMG-ISNSIGSNTFDILLCLGLPWLVKSLFYPS 409 G I N GSN ++ L +GL W + ++++ S Sbjct: 839 GADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSS 872 Score = 46.0 bits (104), Expect = 0.002 Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 3/59 (5%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTE---GDLGVGAVVGSAVFNVLAVPACCALFAGA 182 +A T MA SS+PE+ ++ + + + GDLG G +VGSA +N+ + A C ++ A Sbjct: 180 VANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPA 238 >UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1; Aspergillus oryzae|Rep: K+-dependent Na+:Ca2+ antiporter - Aspergillus oryzae Length = 785 Score = 64.1 bits (149), Expect = 7e-09 Identities = 32/89 (35%), Positives = 51/89 (57%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L FI+ I WI +++ V ++ +G LN+ DS+ GLT+ A G SL + V+ + V + G+ Sbjct: 624 LGFIVAICWIATIATEVVSLLKTLGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 683 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSL 405 M +S G +ILL +GL L +L Sbjct: 684 PVMALSACFGGPMLNILLGIGLGGLYMTL 712 >UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+ antiporter, CaCA family - Fervidobacterium nodosum Rt17-B1 Length = 314 Score = 63.7 bits (148), Expect = 9e-09 Identities = 39/113 (34%), Positives = 62/113 (54%), Gaps = 7/113 (6%) Query: 318 TFIMCITWIGSVSYLV---AWIITVVGD---TLNVPDSITGLTILAAGTSLPEAVSSVLV 371 T I + IG ++ LV WI+ D V D + GLTI+AAGTS+PE +S+ Sbjct: 169 TIISILYIIGGLAGLVFGGRWIVNGAVDIAKAFGVSDKLIGLTIVAAGTSIPELATSLAA 228 Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRI 424 +G+ + + N++GSN F++ LG+ ++K + Y +T N VT L I + Sbjct: 229 IIKGNNEIALGNAVGSNIFNVFFILGISAVIKPIVY-TTVLNFDVTLLVIITV 280 Score = 51.6 bits (118), Expect = 4e-05 Identities = 25/98 (25%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 ++L L + F+ + S+ D V + ++L ++ + G T +A +S+PEL +N V Sbjct: 1 MILSILLLIIGFVFV-SIGSDKLVEGASTLAKKLKVSDLLIGLTIVAFGTSAPELAVNIV 59 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 + ++ +G V+GS +FN+L V A+ +++ Sbjct: 60 SSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPVIVQ 97 Score = 51.2 bits (117), Expect = 5e-05 Identities = 24/60 (40%), Positives = 39/60 (65%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L V D + GLTI+A GTS PE +++ + +G + + N IGSN F+IL+ +GL +++ Sbjct: 33 LKVSDLLIGLTIVAFGTSAPELAVNIVSSIKGTSNISLGNVIGSNIFNILVVVGLSAVIR 92 Score = 39.9 bits (89), Expect = 0.13 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 3/115 (2%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + ++ + G T +AA +S PEL + ++ +G VGS +FNV + Sbjct: 197 IAKAFGVSDKLIGLTIVAAGTSIPELATSLAAIIKGNNEIALGNAVGSNIFNVFFILGIS 256 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 A+ V + D + L+L + KI E LL+V Y Y + Sbjct: 257 AVIKPIVYTT---VLNFDVTLLVIITVILLLFSKNLKIEKFEGLLMVSTYVGYTI 308 >UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum symbiosum Length = 294 Score = 63.7 bits (148), Expect = 9e-09 Identities = 27/83 (32%), Positives = 52/83 (62%) Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGIS 382 + +G+ ++L V+ + + + G T++A GTSLPE V+SV+ K+GH +G+ Sbjct: 161 VALLGAGAWLAVENAVVLARAFGLSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVG 220 Query: 383 NSIGSNTFDILLCLGLPWLVKSL 405 N IGSN ++IL+ +G+ ++ ++ Sbjct: 221 NIIGSNIYNILMIMGVASMIAAV 243 Score = 41.1 bits (92), Expect = 0.054 Identities = 17/69 (24%), Positives = 35/69 (50%) Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 ++ ++ + G T +A +S PEL + V D+GVG ++GS ++N+L + Sbjct: 177 VLARAFGLSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGV 236 Query: 176 CALFAGAVI 184 ++ A + Sbjct: 237 ASMIAAVPV 245 Score = 39.1 bits (87), Expect = 0.22 Identities = 18/67 (26%), Positives = 39/67 (58%), Gaps = 4/67 (5%) Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 W+++ ++ + + G+T++A GTS PE +S+ + + HG + + N IGSN + Sbjct: 8 WLVSGGVMLARRFGISSLVIGMTVVAYGTSTPELAASLAASGE-HGELILGNVIGSNIAN 66 Query: 392 ILLCLGL 398 + + +G+ Sbjct: 67 VGMIIGI 73 >UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 precursor (Na(+)/Ca(2+)-exchange protein 6); n=2; Caenorhabditis|Rep: Putative sodium/calcium exchanger 6 precursor (Na(+)/Ca(2+)-exchange protein 6) - Caenorhabditis elegans Length = 590 Score = 63.7 bits (148), Expect = 9e-09 Identities = 30/87 (34%), Positives = 51/87 (58%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F+M I WI +S V ++T++G V + GLTILA S+ + ++ V V KQG+ Sbjct: 436 FLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPR 495 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405 M ++ +IG F++L+ GLP+ + + Sbjct: 496 MAMAAAIGGQLFNLLIGFGLPFTIAKI 522 Score = 50.0 bits (114), Expect = 1e-04 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 3/75 (4%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---INCVGTFVT 152 L F+++ S +D+F P+I I L I+ +AG TFMA + +P++F + + + Sbjct: 108 LVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTP 167 Query: 153 EGDLGVGAVVGSAVF 167 + DL +G + G+ +F Sbjct: 168 KADLALGELFGAGLF 182 >UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 441 Score = 63.3 bits (147), Expect = 1e-08 Identities = 29/109 (26%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 +++A +P +S +TF++ + +I ++ ++ + T+ G + + +T +T +A G Sbjct: 252 VIFACVPPPHFLNSRGYITFVVALCFIAVLTAIIGDLATIFGCLIGLLAPVTAITFVALG 311 Query: 360 TSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 TSLP+ S + I N GSN+ ++ L LGLPWL+ ++++ Sbjct: 312 TSLPDTFASKTAAVNEATADNSIGNVTGSNSVNVFLGLGLPWLIAAIYW 360 >UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana (Mouse-ear cress) Length = 570 Score = 63.3 bits (147), Expect = 1e-08 Identities = 45/180 (25%), Positives = 86/180 (47%), Gaps = 7/180 (3%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 G ++L +L + F LLG YF P+++ + + L ++ +AG T ++ + +P+LF + Sbjct: 101 GHLVLSAWLFVL-FYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSS 159 Query: 146 CVG-TFVTEGDLGVGAVVGSAVF-NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXX 203 V T GD G+ +++G A F + V C L + +D S RD + Sbjct: 160 VVSFTRSNNGDFGLNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALC 219 Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI--LEKINPLDASQRMTPRSVQNGD--LERGIEM 259 L L + K+ AL + +Y Y+ L + D +RM+ + +++ + E G+ + Sbjct: 220 CLGLIIFIGKVTIWVALCYLSIYLLYVGFLSVSHFFDRKKRMSDQILRSREDLAEMGVSL 279 Score = 46.8 bits (106), Expect = 0.001 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 4/94 (4%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--- 375 F M +TW ++ + ++ +G+ + S+ GLT+LA G SL + +++V V G Sbjct: 410 FTMSVTWTYMIAQELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAFHGGND 469 Query: 376 HGTMGISNSIGSNTFDILLCLGLPWLVKSLF-YP 408 + +S F+ ++ LG+P ++ SL YP Sbjct: 470 GAQIALSGCYAGPLFNTVIGLGVPLVISSLAEYP 503 >UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein; n=1; Clostridium tetani|Rep: Putative sodium/calcium exchanger protein - Clostridium tetani Length = 347 Score = 62.9 bits (146), Expect = 2e-08 Identities = 76/311 (24%), Positives = 133/311 (42%), Gaps = 51/311 (16%) Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE--GDLGVGAV 161 S D A+ I+ +L I + + GATF A +SS PE + V + D+GV + Sbjct: 26 SKASDKLGDALHILGVKLKIPTSVRGATFDAISSSFPEFSTAMIAVIVYKRFTDVGVPTI 85 Query: 162 VGSAVFNVLAVP-ACCALFAG--AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218 GS VFN+L +P A + G +I++D V RD + Y L+ Sbjct: 86 AGSGVFNILIIPMATIFAYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYLGSYTVFA 145 Query: 219 ALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSF 278 ++LVL+Y YI L + +++ E + ++ +++ T S+ Sbjct: 146 GIVLVLIYIGYIF----VLYGETKNYRKNIS--------EENKAYEEIAAELDTEEDMSY 193 Query: 279 PGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIIT 338 K+F ++ I LI W +I I T I T+ Y+V+ + Sbjct: 194 --------LKIFIIMAITIALI-WVSIDGI-----IQSTTVIS--TFFNIPQYIVS--VV 235 Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 ++ ++PD T+L+ +S + G ++N++GSN FDI +CLG+ Sbjct: 236 IIAACTSIPD-----TLLSIKSS-----------QDGDVEGAVANAVGSNIFDICICLGV 279 Query: 399 PWLVKSLFYPS 409 P ++ P+ Sbjct: 280 PIIIAGKTLPA 290 >UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyces pombe CaCA sodium/calcium exchanger; n=1; Yarrowia lipolytica|Rep: Similar to tr|P87122 Schizosaccharomyces pombe CaCA sodium/calcium exchanger - Yarrowia lipolytica (Candida lipolytica) Length = 812 Score = 62.9 bits (146), Expect = 2e-08 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 3/148 (2%) Query: 84 QHGFILLHCFL-ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPEL 142 Q F+L+ L L F+ LG D+ P + I L ++ +AG TF+A + SP+L Sbjct: 92 QRPFLLIMLLLWLLTLFMTLGIAASDFLCPNLGTISSLLGMSESLAGVTFLAFGNGSPDL 151 Query: 143 FINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXX 202 F + G L +G ++G+A F V AL ++ S RD + Sbjct: 152 FSTYSSMKIGSGSLAIGELIGAASFISAVVVGAMAL--ARPFKVARKSFVRDIGFFTAAV 209 Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFYI 230 + + D K+ E +L++++Y Y+ Sbjct: 210 LCTMAFISDGKLRRSECILMLIIYMIYV 237 Score = 56.0 bits (129), Expect = 2e-06 Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F+ I W+ ++ +V ++ +G L + D + GLT+ A G SL + +++ + K G Sbjct: 659 FLTSIAWVSHIADVVVGVLKALGAILGISDPVLGLTVFAFGNSLGDLIANTTIAKMGFPM 718 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRIN 425 M +S G ++L+ +G V L S+P N Y I I+ Sbjct: 719 MALSACFGGPLLNVLVGVG----VSGLIVTSSPGNAVKNGSYHIEIS 761 Score = 35.1 bits (77), Expect = 3.6 Identities = 17/58 (29%), Positives = 30/58 (51%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + L + +S+ G+T LA G P+ S+ K G G++ I IG+ +F + +G Sbjct: 126 ISSLLGMSESLAGVTFLAFGNGSPDLFSTYSSMKIGSGSLAIGELIGAASFISAVVVG 183 >UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2; Sordariomycetes|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1004 Score = 62.9 bits (146), Expect = 2e-08 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 3/145 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F LL +LAL F +G D+F + I L ++ +AG TF+A + SP++F Sbjct: 101 FGLLAAWLALL-FTTIGIAASDFFSINLSTIASILGLSESLAGVTFLAFGNGSPDVFSTF 159 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 G + VG ++G+A F V AL ++ + RD + + Sbjct: 160 AAMGSNSGSMAVGELIGAAGFITAVVAGSMALV--REFKVVKRTFVRDICFFILAASFAM 217 Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231 L D +++ E +++V Y FY++ Sbjct: 218 AVLADGHLHFWECIIMVAFYIFYVM 242 Score = 61.7 bits (143), Expect = 4e-08 Identities = 34/104 (32%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 297 IRLILWATIPDCRHR-HSIYP-LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLT 354 + L+L +T P+ R R H ++ L FI+ + WI +V+ V ++ G L + ++I GLT Sbjct: 809 LALLLSSTSPNVRPRYHFLFCFLGFIISVAWISTVAGEVVGVLKAFGVILGISEAILGLT 868 Query: 355 ILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 I A G SL + V+ + V + G+ M ++ G +ILL +G+ Sbjct: 869 IFAVGNSLGDLVADITVARLGYPVMALAACFGGPMLNILLGIGI 912 Score = 34.3 bits (75), Expect = 6.2 Identities = 17/67 (25%), Positives = 31/67 (46%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 ++ + L + +S+ G+T LA G P+ S+ G+M + IG+ F + Sbjct: 127 LSTIASILGLSESLAGVTFLAFGNGSPDVFSTFAAMGSNSGSMAVGELIGAAGFITAVVA 186 Query: 397 GLPWLVK 403 G LV+ Sbjct: 187 GSMALVR 193 >UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca exchanger - Aedes aegypti (Yellowfever mosquito) Length = 583 Score = 62.5 bits (145), Expect = 2e-08 Identities = 34/144 (23%), Positives = 74/144 (51%), Gaps = 3/144 (2%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 + L F+ + CF +L + + +F P + +I + L+I+ +AG T +A + SP+LF V Sbjct: 77 VALLTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLF-TAV 135 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207 + +L G ++G+ +F V+ + A L + +V RD + + + + Sbjct: 136 SNPNDDTELMFGELLGAGLF-VVGIVAGTILVI-RPFHVYSAAVVRDVVFFIFAVSWITV 193 Query: 208 TLLDDKIYWHEALLLVLMYTFYIL 231 D++ +A+++V++Y Y++ Sbjct: 194 CAYDERFTLSDAIVVVVVYVLYLV 217 Score = 49.6 bits (113), Expect = 2e-04 Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Query: 312 HSIYPL-TFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL 370 H +Y L F+ I I V+ V ++ +G L + S+ GL++LA G S+ + S++ Sbjct: 407 HLVYALLAFVGSIQVIYVVAQEVVSLLMTLGLVLELSKSMLGLSVLAWGNSIGDLFSNIA 466 Query: 371 VTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 + K+G+G M + G F++ L LG +V++ Sbjct: 467 LAKRGYGKMAFAACFGGPLFNLCLGLGSTMIVRA 500 Score = 35.9 bits (79), Expect = 2.0 Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 3/56 (5%) Query: 317 LTF--IMCITWIGSVS-YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369 LTF I+C T + + + ++ V+ TL++ +S+ G+TILA G P+ ++V Sbjct: 80 LTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLFTAV 135 >UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family transporter precursor; n=1; Thiomicrospira crunogena XCL-2|Rep: Ca2+:cation antiporter (CaCA) family transporter precursor - Thiomicrospira crunogena (strain XCL-2) Length = 329 Score = 62.1 bits (144), Expect = 3e-08 Identities = 26/71 (36%), Positives = 44/71 (61%) Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 ++ W + + +VP+ I GLTI+A GTSLPE +++ K+G + I N +GSN F+ Sbjct: 196 MMVWGAVEIAEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKKGEADLMIGNILGSNLFN 255 Query: 392 ILLCLGLPWLV 402 +L + +P L+ Sbjct: 256 LLAVMSMPALI 266 Score = 45.6 bits (103), Expect = 0.003 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 A+EI E ++ I G T +A +S PEL E DL +G ++GS +FN+LAV Sbjct: 201 AVEI-AEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKKGEADLMIGNILGSNLFNLLAV 259 Query: 173 PACCALFAGAVIE 185 + AL A +VI+ Sbjct: 260 MSMPALIAPSVID 272 Score = 40.7 bits (91), Expect = 0.072 Identities = 20/67 (29%), Positives = 36/67 (53%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 +N+ I G+ +L GTS PE + ++L + + I N +GSN +I L LG+ ++ Sbjct: 37 MNISPLIIGVVVLGFGTSAPEILVAILASIDNSPGLAIGNVVGSNIANIGLVLGVTAIIS 96 Query: 404 SLFYPST 410 + S+ Sbjct: 97 PVVIKSS 103 Score = 39.5 bits (88), Expect = 0.17 Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 8/163 (4%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 + L+ L L D F+ +NI+ I G + +S+PE+ + + + Sbjct: 10 IVLFVGLALLVWSSDIFIEGAASTAIHMNISPLIIGVVVLGFGTSAPEILVAILASIDNS 69 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD-- 211 L +G VVGS + N+ V A+ + VI+ + R+ + IL +LD Sbjct: 70 PGLAIGNVVGSNIANIGLVLGVTAIISPVVIKSS--LLKREFPILLGISLVGILLMLDKD 127 Query: 212 ----DKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQN 250 D I LL+V+ + + I+P D T +++ Sbjct: 128 LDITDGIILLALLLIVMTWMIRANKNISPSDPLAEETIEEIED 170 >UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein; n=1; marine gamma proteobacterium HTCC2080|Rep: Putative sodium/calcium exchanger protein - marine gamma proteobacterium HTCC2080 Length = 321 Score = 62.1 bits (144), Expect = 3e-08 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 IGS LV W + ++ V + + GLTI+A GTSLPE +S++ +GH + I + Sbjct: 179 IGSSKALV-WAAVNIAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGAVV 237 Query: 386 GSNTFDILLCLGLPWLVKSLFYPST 410 GSN F++L+ L +P L L +T Sbjct: 238 GSNMFNLLIVLAIPGLFSPLELSTT 262 Score = 47.6 bits (108), Expect = 6e-04 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I E ++ + G T +A +S PEL + V D+ +GAVVGS +FN+L V A Sbjct: 192 IAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGAVVGSNMFNLLIVLAIP 251 Query: 177 ALFAGAVIELDWWSVTRD 194 LF + +EL + RD Sbjct: 252 GLF--SPLELSTTDLQRD 267 Score = 45.6 bits (103), Expect = 0.003 Identities = 21/61 (34%), Positives = 34/61 (55%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409 I G+T+++ GTS PE + S+ G G + + N+ GSN +I L LGL ++ + Sbjct: 39 IIGMTVVSLGTSAPEILVSLSAAASGAGALAVGNAFGSNIANIGLVLGLTLIISPILVGR 98 Query: 410 T 410 T Sbjct: 99 T 99 Score = 34.3 bits (75), Expect = 6.2 Identities = 16/62 (25%), Positives = 29/62 (46%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D F+ + R ++ I G T ++ +S+PE+ ++ G L VG GS + Sbjct: 20 DLFIKGAAAVASRFGMSPLIIGMTVVSLGTSAPEILVSLSAAASGAGALAVGNAFGSNIA 79 Query: 168 NV 169 N+ Sbjct: 80 NI 81 >UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 858 Score = 62.1 bits (144), Expect = 3e-08 Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F +L +LA+ F +G D+ + I L ++ + G TF+A + SP++F Sbjct: 175 FAILAVWLAVL-FNTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFSTF 233 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 G L +G +VG+A F V AL + S RD + + + Sbjct: 234 AAMNSNSGGLAIGELVGAAGFITAVVAGSMALV--RPFRVARRSFVRDVVFFVFSASFTM 291 Query: 207 LTLLDDKIYWHEALLLVLMYTFYI 230 + L D K+Y E + ++L Y FY+ Sbjct: 292 VLLADGKLYAWECVAMILSYVFYV 315 Score = 61.3 bits (142), Expect = 5e-08 Identities = 32/97 (32%), Positives = 54/97 (55%) Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368 R R + L F++ I WI +++ V ++ +G L++ DS+ GLTI A G SL + V+ Sbjct: 675 RFRPFVAFLGFVVSIAWISTLASEVVNLLKAIGVILSISDSLLGLTIFAVGNSLGDLVAD 734 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + V + G+ M +S G +ILL +G+ L +L Sbjct: 735 ITVARLGYPVMALSACFGGPMLNILLGVGMGGLYMTL 771 Score = 35.1 bits (77), Expect = 3.6 Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 9/104 (8%) Query: 308 CRHRHSIYPLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 C+ H+ P+ F + W+ + S + ++ + L + +S+TG+T LA G Sbjct: 165 CKLAHA-KPIAFAILAVWLAVLFNTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFG 223 Query: 360 TSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 P+ S+ G + I +G+ F + G LV+ Sbjct: 224 NGSPDVFSTFAAMNSNSGGLAIGELVGAAGFITAVVAGSMALVR 267 >UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: Uvs037 - uncultured bacterium Length = 354 Score = 61.7 bits (143), Expect = 4e-08 Identities = 29/60 (48%), Positives = 42/60 (70%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 V +++ GLTI+AAGTSLPE V+SV+ T +G + + N +GSN F+IL LG+ LV + Sbjct: 201 VNEAVIGLTIVAAGTSLPEVVTSVVATIKGERDIAVGNVVGSNIFNILCVLGISGLVSPI 260 Score = 52.8 bits (121), Expect = 2e-05 Identities = 26/60 (43%), Positives = 35/60 (58%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 VP + GLT++A GTS PE SV G + I+N +GSN F+IL LG+ L+ L Sbjct: 33 VPALVIGLTVVAFGTSAPELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALISPL 92 Score = 50.0 bits (114), Expect = 1e-04 Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 5/141 (3%) Query: 93 FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 ++ L+ L+L + D V + + + + G T +A +S+PEL ++ F Sbjct: 3 WVLLFAGLVLLVIGADLLVKGAARLAANFGVPALVIGLTVVAFGTSAPELAVSVKAAFSG 62 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 + +L + VVGS +FN+L + AL + +I + +D + +L LD Sbjct: 63 QAELAIANVVGSNIFNILFILGVAALISPLIISHQ--LIRQDVPIMVGVSIVAVLMTLDG 120 Query: 213 KIYWHEALLL---VLMYTFYI 230 I EA +L ++ YT+++ Sbjct: 121 NINKLEASILTIGLISYTWFL 141 Score = 44.8 bits (101), Expect = 0.004 Identities = 21/46 (45%), Positives = 29/46 (63%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 + G T +AA +S PE+ + V T E D+ VG VVGS +FN+L V Sbjct: 205 VIGLTIVAAGTSLPEVVTSVVATIKGERDIAVGNVVGSNIFNILCV 250 >UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family precursor - Marinomonas sp. MWYL1 Length = 332 Score = 61.7 bits (143), Expect = 4e-08 Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 IGS S L+ W + L V + + GLTI+A GTSLPE +SV ++GH + I N + Sbjct: 193 IGS-SKLLVWGAIGIATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIAIGNIL 251 Query: 386 GSNTFDILLCLGLPWLV 402 GSN F++ L LP L+ Sbjct: 252 GSNIFNLATVLPLPALL 268 Score = 49.6 bits (113), Expect = 2e-04 Identities = 26/91 (28%), Positives = 47/91 (51%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 +AL L+L + D F+ ++ E+LN+ I G T +A +S+PE+ ++ + Sbjct: 18 IALIVGLILLVMSSDKFIEHSALVAEKLNVNPMIIGITLVAFGTSAPEMVVSAIAALDNA 77 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 ++ VG V+GS + N+ V LF+ I Sbjct: 78 PEIAVGNVLGSNIANIALVFGITLLFSAIPI 108 Score = 46.0 bits (104), Expect = 0.002 Identities = 23/67 (34%), Positives = 36/67 (53%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 +V + LNV I G+T++A GTS PE V S + + + N +GSN +I L G+ Sbjct: 40 LVAEKLNVNPMIIGITLVAFGTSAPEMVVSAIAALDNAPEIAVGNVLGSNIANIALVFGI 99 Query: 399 PWLVKSL 405 L ++ Sbjct: 100 TLLFSAI 106 Score = 37.1 bits (82), Expect = 0.88 Identities = 19/69 (27%), Positives = 34/69 (49%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I L ++ + G T +A +S PEL + D+ +G ++GS +FN+ V Sbjct: 206 IATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIAIGNILGSNIFNLATVLPLP 265 Query: 177 ALFAGAVIE 185 AL A +++ Sbjct: 266 ALLAPGLVD 274 >UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 320 Score = 61.7 bits (143), Expect = 4e-08 Identities = 29/67 (43%), Positives = 39/67 (58%) Query: 333 VAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDI 392 V W + + TL V D + GLT++A GTSLPE +SV +G M I N +GSN F++ Sbjct: 186 VVWGASEIASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNL 245 Query: 393 LLCLGLP 399 L L P Sbjct: 246 LAVLPFP 252 Score = 45.2 bits (102), Expect = 0.003 Identities = 21/62 (33%), Positives = 35/62 (56%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + V + G+ I+ GTS PE + S + G G + + N++GSN +I L LG+ L+K Sbjct: 35 MGVSPLLVGMLIVGLGTSAPEMLVSAMAALDGSGGIALGNAVGSNITNIGLVLGVSALIK 94 Query: 404 SL 405 + Sbjct: 95 PI 96 Score = 39.5 bits (88), Expect = 0.17 Identities = 26/127 (20%), Positives = 55/127 (43%), Gaps = 2/127 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + R+ ++ + G + +S+PE+ ++ + G + +G VGS + Sbjct: 22 DRFVFGASTLARRMGVSPLLVGMLIVGLGTSAPEMLVSAMAALDGSGGIALGNAVGSNIT 81 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ V AL + D V R+ + ++L L+D ++ + +LV Sbjct: 82 NIGLVLGVSALIKPIRLHRD--VVRREIPVVLLITFGVVLLLVDWQLRPVDGAILVATLI 139 Query: 228 FYILEKI 234 +++ I Sbjct: 140 LFLVRAI 146 Score = 38.7 bits (86), Expect = 0.29 Identities = 20/56 (35%), Positives = 30/56 (53%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I L ++ + G T +A +S PEL + E + +G V+GS VFN+LAV Sbjct: 193 IASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNLLAV 248 >UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+ antiporter, CaCA family - Candidatus Nitrosopumilus maritimus SCM1 Length = 296 Score = 61.7 bits (143), Expect = 4e-08 Identities = 23/60 (38%), Positives = 42/60 (70%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 ++ + + I GLT++A GTSLPE ++S++ ++GH +G+ N IGSN ++IL+ +G+ Sbjct: 179 ILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILMIMGV 238 Score = 46.4 bits (105), Expect = 0.001 Identities = 21/72 (29%), Positives = 37/72 (51%) Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 I+ + ++ I G T +A +S PEL + + D+GVG ++GS ++N+L + Sbjct: 179 ILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILMIMGV 238 Query: 176 CALFAGAVIELD 187 A G +I D Sbjct: 239 GAALGGVMISDD 250 Score = 38.3 bits (85), Expect = 0.38 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 W+++ + + + + G+TI+A GTS PE +S+ + H + + N IGSN + Sbjct: 8 WLVSGGVAIARKFRISNLVIGMTIVAYGTSTPELAASIAAAGE-HSAIILGNIIGSNIAN 66 Query: 392 ILLCLGL 398 + + +G+ Sbjct: 67 VGMVIGI 73 >UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to sodium-calcium exchanger; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to sodium-calcium exchanger - Strongylocentrotus purpuratus Length = 766 Score = 60.9 bits (141), Expect = 6e-08 Identities = 34/119 (28%), Positives = 69/119 (57%), Gaps = 4/119 (3%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 +++A +P ++ +P F+ + +I +++ +V I T++ + S+ G+TI+A G Sbjct: 583 VIFAMVPP-KNYFGGWP-AFLGSLLFIFALTAVVEQIATLLSCVALIEPSVAGITIIALG 640 Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLF-YPSTPENHWV 416 TS+P+ +S Q H I N GSN+ ++ L LGLPW++K ++ Y ++ + ++V Sbjct: 641 TSVPDTFASRTAAIQDQHADAAIGNITGSNSVNVFLGLGLPWIIKVMYLYVNSDQPYYV 699 Score = 41.1 bits (92), Expect = 0.054 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Query: 127 IAGATFMAAASSSPELFINCVGTF--VTE-----GDLGVGAVVGSAVFNVLAVPACCAL 178 +A T MA SS+PE+ +N V T +TE LG ++GSA FN+L + A C + Sbjct: 103 VANLTLMALGSSAPEILLNTVETLQNLTEPPNRKDSLGTFTIIGSAAFNLLIITAVCVV 161 >UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=2; Chlorobiaceae|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Chlorobium phaeobacteroides BS1 Length = 325 Score = 60.9 bits (141), Expect = 6e-08 Identities = 31/83 (37%), Positives = 49/83 (59%), Gaps = 3/83 (3%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + L +P I GLT++A GTSLPE V+S++ T QG + + N +GSN F++LL G Sbjct: 206 IAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNG-- 263 Query: 400 WLVKSLFYPSTPENHWVTDLYFI 422 + S+ + P N DL+ + Sbjct: 264 -VCSSITQIAVPVNGGFYDLFMM 285 Score = 52.4 bits (120), Expect = 2e-05 Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 4/120 (3%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I E L I I G T +A +S PEL + V TF + D+ VG VVGS +FN+L V C Sbjct: 206 IAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNGVC 265 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK--IYWHEALLLVLMYTFYILEKI 234 + + ++ MM L +++ K + W A+LL MY Y + +I Sbjct: 266 SSITQIAVPVNGGFYDL-FMMILLAVFLLPMSITHKKKIVRWEGAVLLA-MYLGYNVWRI 323 Score = 50.8 bits (116), Expect = 7e-05 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 +G ++LV + + L V + GLT++A GTS PE ++L QG+G + N I Sbjct: 16 LGGGNFLVTGA-SAMARNLGVSPLVIGLTVVAFGTSAPELSINLLGALQGNGGISFGNII 74 Query: 386 GSNTFDILLCLGLPWLVKSL 405 GSN +I L LGL L++ L Sbjct: 75 GSNIANIGLVLGLTALIRPL 94 Score = 44.8 bits (101), Expect = 0.004 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Query: 88 ILLHCFLALYCF-LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 +L+ F+ ++ LLLG ++ V + L ++ + G T +A +S+PEL IN Sbjct: 1 MLIDSFMLVFGLTLLLGG--GNFLVTGASAMARNLGVSPLVIGLTVVAFGTSAPELSINL 58 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 +G G + G ++GS + N+ V AL IE Sbjct: 59 LGALQGNGGISFGNIIGSNIANIGLVLGLTALIRPLTIE 97 >UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; Bacteroidetes|Rep: Putative uncharacterized protein - Algoriphagus sp. PR1 Length = 318 Score = 60.9 bits (141), Expect = 6e-08 Identities = 30/69 (43%), Positives = 44/69 (63%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 V+ + V + I GLTI+AAGTSLPE +SV+ + + + + I N IGSN F+I L LG+ Sbjct: 196 VMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDIAIGNIIGSNIFNIFLILGV 255 Query: 399 PWLVKSLFY 407 ++ L Y Sbjct: 256 SSIINPLDY 264 Score = 48.0 bits (109), Expect = 5e-04 Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 6/94 (6%) Query: 323 ITWIGSVSYLVA---WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 I IG + LV W++ +V+ T V D GLTI+A GTS PE V + + + Sbjct: 6 ILLIGGLLLLVKGADWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHL 65 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPST 410 + N IGSN F++ + LG+ L+ L S+ Sbjct: 66 PDLVFGNVIGSNNFNLFIILGIAGLIAPLSVQSS 99 Score = 46.0 bits (104), Expect = 0.002 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 ++ + ++ I G T +AA +S PEL + V + D+ +G ++GS +FN+ + Sbjct: 196 VMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDIAIGNIIGSNIFNIFLILGV 255 Query: 176 CALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK---IYWHEALLLVLMYTFYI 230 ++ +L S +D + L L + K + EA +L+L Y YI Sbjct: 256 SSIINPLDYQL---SFNKDLYILLGGTIFLFLAMFTGKRKSLDRWEAGILLLTYLVYI 310 Score = 38.3 bits (85), Expect = 0.38 Identities = 20/73 (27%), Positives = 35/73 (47%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V ++ + ++ G T +A +S+PEL +N + + DL G V+GS F Sbjct: 20 DWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHLPDLVFGNVIGSNNF 79 Query: 168 NVLAVPACCALFA 180 N+ + L A Sbjct: 80 NLFIILGIAGLIA 92 >UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS Length = 253 Score = 60.5 bits (140), Expect = 8e-08 Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 5/100 (5%) Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIIT---VVGDTLNVPDSITGLTILAAGTSLPEA 365 RH H I L FI + +G + W++ V+ + + I LT+++ GTSLPE Sbjct: 60 RHLHIILQLVFI--VAGLGLLVQGSNWLVNGAIVIAQFYGISELIIALTVISIGTSLPEL 117 Query: 366 VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + ++ T +G + + N +GSN F+ILL LGL LV + Sbjct: 118 ATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPI 157 Score = 47.2 bits (107), Expect = 8e-04 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 6/147 (4%) Query: 90 LHCFLALYCFLL-LGSVCE--DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 LH L L + LG + + ++ V +I + I+ I T ++ +S PEL Sbjct: 62 LHIILQLVFIVAGLGLLVQGSNWLVNGAIVIAQFYGISELIIALTVISIGTSLPELATVI 121 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 +GTF E +L VG VVGS +FN+L V L + I++ ++ D + + Sbjct: 122 IGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVSQAAIFLDMPVMIAVAIACL 181 Query: 207 LTLLDDKI-YWHEALLLV--LMYTFYI 230 ++ I W L L + YT Y+ Sbjct: 182 PIFFNNLIERWEGGLFLAYYIAYTLYL 208 >UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 737 Score = 60.5 bits (140), Expect = 8e-08 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Query: 290 FWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDS 349 F L W + ++A +P C +TF + + +IG ++ +V + T+ G + + + Sbjct: 625 FLTLAWKV---IFAAVPPCTWAGGW--VTFSVALCFIGILTAIVGDLATIFGCLVGLKNE 679 Query: 350 ITGLTILAAGTSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406 +T T +A GTSLP+ S + + I N GSN+ ++ L LG PW++ +++ Sbjct: 680 VTAFTFVALGTSLPDLFASKAAAINEKYADACIGNVTGSNSVNVFLGLGTPWVIATIY 737 Score = 39.9 bits (89), Expect = 0.13 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL 178 +A T MA SS+PE+ ++ + + G LG +VGSA FN+L + C + Sbjct: 98 VANLTLMALGSSAPEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVM 153 >UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 837 Score = 60.5 bits (140), Expect = 8e-08 Identities = 33/109 (30%), Positives = 66/109 (60%), Gaps = 3/109 (2%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 +L+A IP R +P F++ + +I +++ ++ + ++G +++ +S+TG+TI+A G Sbjct: 651 VLFAFIPP-RPLLGGWP-AFVVSLLFIAALTAVIEQLGKLLGCVVDLRNSVTGITIIAIG 708 Query: 360 TSLPEAVSSVLVTKQGHGT-MGISNSIGSNTFDILLCLGLPWLVKSLFY 407 TSLP+ ++S Q G I N G N+ ++ L LGLPW++ + ++ Sbjct: 709 TSLPDTMASRSAALQDTGADAAIGNITGYNSVNVFLGLGLPWVMSTCYH 757 Score = 35.5 bits (78), Expect = 2.7 Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 10/61 (16%) Query: 127 IAGATFMAAASSSPELFINCVGT---------FVTEGDLGVGAVVGSAVFNVLAVPACCA 177 +A T MA SS+PE+ + V T T+G LG +VGSA FN+L + A C Sbjct: 95 VANLTLMALGSSAPEILLAVVETGQELALGQTTATDG-LGTFTIVGSASFNLLLITAVCV 153 Query: 178 L 178 + Sbjct: 154 V 154 >UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces cerevisiae YDL206w; n=1; Kluyveromyces lactis|Rep: Similar to sgd|S0002365 Saccharomyces cerevisiae YDL206w - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 684 Score = 60.5 bits (140), Expect = 8e-08 Identities = 38/132 (28%), Positives = 73/132 (55%), Gaps = 6/132 (4%) Query: 287 KKLFWVLTWPIRLIL---WATIPDCRHRHSIYPLTFIMCITWIGSVS--YLVAWIITVVG 341 +KLF VLT+ + L + +A + D R+ PL+ + C +G ++ YL + + Sbjct: 6 RKLF-VLTFYLGLTVIVGFAQLSDEVFRYVFSPLSLLTCFIALGIITSDYLTPNLTVISQ 64 Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401 + L + D I+G+T+LA G ++P+ S+ K+G T+ I S+G+ F + + +G L Sbjct: 65 ELLFISDRISGMTLLALGNAIPDITSTYKAMKRGTTTLAIGESLGAIFFLLTVVIGSMLL 124 Query: 402 VKSLFYPSTPEN 413 V+++ + PE+ Sbjct: 125 VRNIKLSTPPES 136 Score = 44.0 bits (99), Expect = 0.008 Identities = 26/80 (32%), Positives = 44/80 (55%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F++ I+ I V LV I+T +T N+ ++I GLT+ A G S+ + VS+V T+ G Sbjct: 524 FVLSISSISFVVGLVLDILTNWAETFNLSEAILGLTVFAWGNSIGDLVSNVTFTRIGVLE 583 Query: 379 MGISNSIGSNTFDILLCLGL 398 + + + GS L +G+ Sbjct: 584 IALGSCFGSPLLYFLFGVGV 603 Score = 39.9 bits (89), Expect = 0.13 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASD-IAGATFMAAASSSPELFINCVGTFVTEG 154 L CF+ LG + DY P + +I + L SD I+G T +A ++ P++ Sbjct: 41 LTCFIALGIITSDYLTPNLTVISQELLFISDRISGMTLLALGNAIPDITSTYKAMKRGTT 100 Query: 155 DLGVGAVVGSAVFNVLAV 172 L +G +G A+F +L V Sbjct: 101 TLAIGESLG-AIFFLLTV 117 >UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida albicans IPF11817 unknown function; n=1; Debaryomyces hansenii|Rep: Similar to CA1231|IPF11817 Candida albicans IPF11817 unknown function - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 710 Score = 60.5 bits (140), Expect = 8e-08 Identities = 39/181 (21%), Positives = 81/181 (44%), Gaps = 4/181 (2%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 LL C L F+ LG DY P + I + L ++ ++AG T +A + SP++ Sbjct: 86 LLSCLSLL--FIALGMTASDYLCPNLYTISKFLELSDNLAGLTLLAFGNGSPDVLSTYKA 143 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208 + G L + ++G+A+F + + A+ + D + RD + ++++ Sbjct: 144 MSLDSGSLAISELMGAALFIITVIVGSMAVVHPFKVPRDLF--IRDAGFFLGVIALVLIS 201 Query: 209 LLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGS 268 LL+ + +LL+ +Y Y++ + + R V+ +TR D++G+ Sbjct: 202 LLNSYLSMVNCILLIGVYVIYVVIVVLNHSFLKSKIRRRVREERSRGNYSLTRPQDNSGT 261 Query: 269 D 269 + Sbjct: 262 E 262 Score = 37.9 bits (84), Expect = 0.50 Identities = 18/68 (26%), Positives = 32/68 (47%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F + I+WI + + I+ V ++ D I G+T+ A G S+ + +S+ + K G Sbjct: 557 FAIAISWISIFATEIISILKTVSIIYDLSDDILGITVFALGNSIGDFISNFTIAKMGMPL 616 Query: 379 MGISNSIG 386 M G Sbjct: 617 MAFGACFG 624 >UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 1060 Score = 60.5 bits (140), Expect = 8e-08 Identities = 28/90 (31%), Positives = 50/90 (55%) Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368 +HR + + F++ I WI +++ V ++ G L + D+I GLTI A G SL + V+ Sbjct: 872 KHRFVLCFVGFVVAIAWISTIANEVVGVLKAFGVILGISDAILGLTIFAVGNSLGDLVAD 931 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + V + G+ M +S G +IL+ +G+ Sbjct: 932 ITVARLGYPVMALSACFGGPMLNILIGIGV 961 Score = 55.6 bits (128), Expect = 2e-06 Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F +L +L L F +G D+F + I L ++ +AG TF+A + SP++F Sbjct: 119 FAILILWLGLL-FSTIGIAASDFFCINLSTIASILGMSESMAGVTFLAFGNGSPDVFSTF 177 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 G L VG ++G+A F V AL ++ + RD + + Sbjct: 178 AAMSSHSGSLAVGELIGAAGFITAVVAGSMALV--REFKVGKKTFVRDIGFFIVAASFSM 235 Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231 + L D ++ E +++ Y FY++ Sbjct: 236 VFLADGALHLWECFVMIGFYLFYVV 260 Score = 35.9 bits (79), Expect = 2.0 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 8/96 (8%) Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367 PL F + I W+G + S ++ + L + +S+ G+T LA G P+ S Sbjct: 116 PLAFAILILWLGLLFSTIGIAASDFFCINLSTIASILGMSESMAGVTFLAFGNGSPDVFS 175 Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + G++ + IG+ F + G LV+ Sbjct: 176 TFAAMSSHSGSLAVGELIGAAGFITAVVAGSMALVR 211 >UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisphaera araneosa HTCC2155|Rep: Sodium/calcium exchanger - Lentisphaera araneosa HTCC2155 Length = 319 Score = 60.1 bits (139), Expect = 1e-07 Identities = 25/62 (40%), Positives = 43/62 (69%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L V ++ GLTI+A GTSLPE +S++ + +GHG M + N IGS F++L +G+ +++ Sbjct: 201 LGVSQAVIGLTIVALGTSLPELAASIMASLKGHGDMALGNVIGSCIFNLLAIMGITSMIE 260 Query: 404 SL 405 ++ Sbjct: 261 TI 262 Score = 47.6 bits (108), Expect = 6e-04 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 4/83 (4%) Query: 94 LALYCFLLLGSVCEDY----FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149 LAL+ + G Y FV I L ++ + G T +A +S PEL + + + Sbjct: 170 LALFGLIFAGLAGVTYGGSIFVDGASTIAAGLGVSQAVIGLTIVALGTSLPELAASIMAS 229 Query: 150 FVTEGDLGVGAVVGSAVFNVLAV 172 GD+ +G V+GS +FN+LA+ Sbjct: 230 LKGHGDMALGNVIGSCIFNLLAI 252 Score = 41.5 bits (93), Expect = 0.041 Identities = 21/56 (37%), Positives = 31/56 (55%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + GLT++A GTS PE + T G + + N IGSN +I L L + L+K + Sbjct: 39 VVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNICNIGLVLAIAALLKPI 94 Score = 38.3 bits (85), Expect = 0.38 Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 2/123 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V + R ++ + G T +A +S+PEL + T D+ +G V+GS + Sbjct: 20 DWLVDGAVGLSLRWGMSPLVVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNIC 79 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ V A AL ++ + D + L + D ++ + ++L M Sbjct: 80 NIGLVLAIAALLKPIAVQSQLIKI--DVPVSIIAALAFFLQIQDGQLDFSNGIILFAMVV 137 Query: 228 FYI 230 Y+ Sbjct: 138 CYV 140 >UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 221 Score = 60.1 bits (139), Expect = 1e-07 Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%) Query: 289 LFWVLTWPIRL--ILWATIPDCRHRHSIYP--LTFIMCITWIGSVSYLVAWIITVVGDTL 344 L+ +LT I L +L T P + R+ L FI+ + WI +++ V ++ +G L Sbjct: 3 LYTLLTSLILLAALLATTTPHKKPRYHFLLCFLGFIISVAWISTIAGEVVGVLKALGVIL 62 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + ++I GLT+ A G SL + V+ V V + G+ M ++ S+G +ILL +G+ Sbjct: 63 GISEAILGLTVFAVGNSLGDLVADVTVARLGYPVMALAASVGGPMLNILLGVGI 116 >UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2; Pezizomycotina|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 1013 Score = 60.1 bits (139), Expect = 1e-07 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 3/145 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F+++ +L+L F +G D+ + I L ++ + G TF+A + SP++F Sbjct: 118 FVIIALWLSLL-FSTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFSTF 176 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 G L +G ++G+A F V AL + S RD + + Sbjct: 177 AAMSSNSGSLAIGELIGAAGFISAVVAGSMALV--RPFRVARRSFVRDIAFFTCAATVSL 234 Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231 + + D K+Y E +L++ Y FY++ Sbjct: 235 VFIADGKLYIWECVLMIGFYIFYVV 259 Score = 60.1 bits (139), Expect = 1e-07 Identities = 33/105 (31%), Positives = 58/105 (55%), Gaps = 1/105 (0%) Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368 R R + L F++ I WI +++ V ++ +G L++ DS+ GLT+ A G SL + V+ Sbjct: 827 RARPFVAFLGFLVSIAWISTLATEVVNVLKSIGVILSISDSLLGLTVFAVGNSLGDLVAD 886 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413 V V + G+ M +S G +IL+ +G+ L +L P+ P + Sbjct: 887 VTVARLGYPVMALSACFGGPMLNILIGIGVGGLYMTL-SPNQPSS 930 Score = 37.1 bits (82), Expect = 0.88 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 8/96 (8%) Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367 PL F++ W+ + S + ++ + L + +S+TG+T LA G P+ S Sbjct: 115 PLAFVIIALWLSLLFSTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFS 174 Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + G++ I IG+ F + G LV+ Sbjct: 175 TFAAMSSNSGSLAIGELIGAAGFISAVVAGSMALVR 210 >UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 996 Score = 60.1 bits (139), Expect = 1e-07 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F+++ +LA+ F +G D+F + I L ++ +AG T +A + SP++F Sbjct: 109 FVIMTLWLAML-FSTIGIAASDFFCVNLNTIARMLGMSESLAGVTLLAFGNGSPDVFSTF 167 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 L VG ++G+A F V AL + S RD + + Sbjct: 168 AAFRTHAASLAVGELIGAACFITAVVSGSMALIRPFAVARK--SFIRDVGFFLVAAAFSM 225 Query: 207 LTLLDDKIYWHEALLLVLMYTFYI 230 ++D K++ E+L +V Y FY+ Sbjct: 226 GFIIDGKLHLWESLAMVAFYIFYV 249 Score = 58.8 bits (136), Expect = 3e-07 Identities = 29/80 (36%), Positives = 45/80 (56%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F + I WI +++ V ++ +G LN+ D+I GLTI A G SL + V+ + V + G Sbjct: 825 FAVAIAWISTIANEVVGVLRTLGVILNMSDAILGLTIFAVGNSLGDLVADITVARLGFPI 884 Query: 379 MGISNSIGSNTFDILLCLGL 398 M +S G +ILL +GL Sbjct: 885 MALSACFGGPMLNILLGIGL 904 >UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=4; Proteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Desulfovibrio desulfuricans (strain G20) Length = 322 Score = 59.7 bits (138), Expect = 1e-07 Identities = 27/69 (39%), Positives = 41/69 (59%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S ++ W + V D I GLTI+A GTSLPE SS++ T++G + + N +GSN Sbjct: 188 SRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALGNVLGSNL 247 Query: 390 FDILLCLGL 398 F+ L +G+ Sbjct: 248 FNTLAVVGI 256 Score = 46.0 bits (104), Expect = 0.002 Identities = 22/60 (36%), Positives = 34/60 (56%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +P + G+ I+ GTS PE V S L QG+ + + N+ GSN +I L LG+ L+ + Sbjct: 35 MPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITNIALILGVTALISPI 94 Score = 40.7 bits (91), Expect = 0.072 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 A+EI ++ I G T +A +S PEL + + T E D+ +G V+GS +FN LAV Sbjct: 195 AVEI-AHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALGNVLGSNLFNTLAV 253 >UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 305 Score = 59.7 bits (138), Expect = 1e-07 Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 6/142 (4%) Query: 97 YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 Y L++G V D+FV + L I S I G T +A +S+PE ++ Sbjct: 3 YLLLIIGFVLLIKGADFFVEGSSSLARFLKIPSVIIGLTIVAMGTSAPEASVSINAALAG 62 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 D+ V ++GS +FN L V CA +G D + RD + L + + + Sbjct: 63 NNDIAVSNIIGSNIFNGLIVVGICAFISGFKTNKD--ILKRDMPVNILITVILCIMIANG 120 Query: 213 KIYWHEALLLVLMYTFYILEKI 234 K+ E +LL+ FYIL I Sbjct: 121 KLSRIEGILLLAGMIFYILNMI 142 Score = 59.7 bits (138), Expect = 1e-07 Identities = 27/63 (42%), Positives = 41/63 (65%) Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 + V + GLTI+A GTSLPE V+S++ T++G + + N+IGSN F+IL LG+ + Sbjct: 191 SFGVSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFNILFILGMSATI 250 Query: 403 KSL 405 L Sbjct: 251 SPL 253 Score = 54.0 bits (124), Expect = 7e-06 Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV- 402 L +P I GLTI+A GTS PEA S+ G+ + +SN IGSN F+ L+ +G+ + Sbjct: 31 LKIPSVIIGLTIVAMGTSAPEASVSINAALAGNNDIAVSNIIGSNIFNGLIVVGICAFIS 90 Query: 403 -----KSLFYPSTPENHWVTDLYFIRINNG 427 K + P N +T + I I NG Sbjct: 91 GFKTNKDILKRDMPVNILITVILCIMIANG 120 Score = 37.1 bits (82), Expect = 0.88 Identities = 17/56 (30%), Positives = 29/56 (51%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I ++ + G T +A +S PEL + V T + L +G +GS +FN+L + Sbjct: 188 IAVSFGVSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFNILFI 243 >UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1; Schizosaccharomyces pombe|Rep: Sodium/calcium exchanger - Schizosaccharomyces pombe (Fission yeast) Length = 743 Score = 59.7 bits (138), Expect = 1e-07 Identities = 26/87 (29%), Positives = 49/87 (56%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F++ I WI +++ V I+ +G N+ +SI GLT+ AAG SL + ++ +++ + G Sbjct: 589 FVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPE 648 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405 M + G T +IL+ +G+ S+ Sbjct: 649 MAMGGVFGGPTLNILIGIGISSFYSSI 675 Score = 52.8 bits (121), Expect = 2e-05 Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 3/137 (2%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155 ++ F+ +G D+F + I L + + G TF+A + SP++ V G Sbjct: 120 IFLFITIGISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNSGG 179 Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLL-DDKI 214 + +G ++GSA F V V L ++ RD +I+ +L D + Sbjct: 180 MAIGELLGSAFFIVAIVAGSVCLI--KPFKIPRRHFLRDVAFLTGTILLVIMFVLHDGSL 237 Query: 215 YWHEALLLVLMYTFYIL 231 ++L+++L Y Y+L Sbjct: 238 SIWQSLVMILYYLLYVL 254 Score = 48.4 bits (110), Expect = 4e-04 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F+ I + + ++T+ L +PDS+ G+T LA G P+ +S+ + Sbjct: 119 LIFLFITIGISASDFFSTNLVTISW-LLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNS 177 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFI 422 G M I +GS F + + G L+K P H++ D+ F+ Sbjct: 178 GGMAIGELLGSAFFIVAIVAGSVCLIKPF---KIPRRHFLRDVAFL 220 >UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=3; Gammaproteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 331 Score = 59.3 bits (137), Expect = 2e-07 Identities = 26/73 (35%), Positives = 43/73 (58%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S ++ W + +V I GLT++A GTSLPE +SV+ +GH + + N IGSN Sbjct: 193 SEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHDIALGNIIGSNI 252 Query: 390 FDILLCLGLPWLV 402 F++L + +P ++ Sbjct: 253 FNLLAVMAVPGII 265 Score = 46.0 bits (104), Expect = 0.002 Identities = 26/88 (29%), Positives = 45/88 (51%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + V + GLTI++ GTS PE + S+ + + G + I N++GSN +I L LG Sbjct: 36 IAKSFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIANIGLVLGAT 95 Query: 400 WLVKSLFYPSTPENHWVTDLYFIRINNG 427 L+ ++ H + L + I +G Sbjct: 96 LLIAAIPVQKHIFRHELPVLLLVTIISG 123 Score = 41.9 bits (94), Expect = 0.031 Identities = 21/81 (25%), Positives = 41/81 (50%) Query: 105 VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGS 164 + + V + E +++ I G T +A +S PEL + + D+ +G ++GS Sbjct: 191 ISSEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHDIALGNIIGS 250 Query: 165 AVFNVLAVPACCALFAGAVIE 185 +FN+LAV A + + ++E Sbjct: 251 NIFNLLAVMAVPGIISPPIME 271 Score = 40.3 bits (90), Expect = 0.095 Identities = 20/78 (25%), Positives = 37/78 (47%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV I + +A + G T ++ +S+PE+ ++ + GDL +G +GS + Sbjct: 27 DRFVAGSAAIAKSFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIA 86 Query: 168 NVLAVPACCALFAGAVIE 185 N+ V L A ++ Sbjct: 87 NIGLVLGATLLIAAIPVQ 104 >UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma proteobacterium HTCC2207|Rep: Putative Ca2+/Na+ antiporter - gamma proteobacterium HTCC2207 Length = 330 Score = 59.3 bits (137), Expect = 2e-07 Identities = 27/80 (33%), Positives = 47/80 (58%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L FI+ + + + + + W + +L + + I GLT++A GTSLPE +SV+ +GH Sbjct: 175 LWFIVGLAVLLASAEVTVWSAKTIAQSLGISELIIGLTVVAIGTSLPELAASVVSAMRGH 234 Query: 377 GTMGISNSIGSNTFDILLCL 396 + I N GSN F+++L + Sbjct: 235 HDIAIGNVFGSNLFNLMLVM 254 Score = 40.7 bits (91), Expect = 0.072 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409 I GLT+++ GTS PE + S+ + + N++GSN +I L LG L+ P+ Sbjct: 42 IIGLTVVSIGTSAPEVLVSINAALSNAAELAVGNALGSNMANIGLVLGATLLIA----PT 97 Query: 410 TPENHWVT 417 + H +T Sbjct: 98 PVQKHLLT 105 Score = 38.3 bits (85), Expect = 0.38 Identities = 21/68 (30%), Positives = 33/68 (48%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + L I+ I G T +A +S PEL + V D+ +G V GS +FN++ V Sbjct: 198 IAQSLGISELIIGLTVVAIGTSLPELAASVVSAMRGHHDIAIGNVFGSNLFNLMLVMPAA 257 Query: 177 ALFAGAVI 184 + + I Sbjct: 258 GIISPMTI 265 >UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; Clostridiales|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 336 Score = 59.3 bits (137), Expect = 2e-07 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 6/109 (5%) Query: 87 FILLHCFLAL-YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 F L+ FL + + FL+ G+ D+FV I ++L + S I G T +A +S PE ++ Sbjct: 10 FALVIMFLIIGFVFLIKGA---DFFVEGSSSIAKKLKVPSIIIGLTIVAMGTSLPETAVS 66 Query: 146 CVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRD 194 + V +L V VVGS +FN++ V CA+ +++ D ++ RD Sbjct: 67 VTASLVHNNELAVSNVVGSNIFNLMFVIGVCAIMTPIMVQKD--TIVRD 113 Score = 57.6 bits (133), Expect = 6e-07 Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 7/89 (7%) Query: 315 YPLTFIMCITWIGSVSYLVAWIITV-----VGDTLNVPDSITGLTILAAGTSLPEAVSSV 369 YP + I+CI G+V+ +TV + L + ++ GLTI++ GTSLPE V+SV Sbjct: 191 YPKS-ILCIVG-GAVAIAFGGDMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSV 248 Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + ++ M + N++GSN F+IL+ LG+ Sbjct: 249 VAARKNEVDMAVGNAVGSNIFNILMVLGI 277 Score = 52.8 bits (121), Expect = 2e-05 Identities = 24/59 (40%), Positives = 36/59 (61%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + L VP I GLTI+A GTSLPE SV + + + +SN +GSN F+++ +G+ Sbjct: 38 IAKKLKVPSIIIGLTIVAMGTSLPETAVSVTASLVHNNELAVSNVVGSNIFNLMFVIGV 96 Score = 44.4 bits (100), Expect = 0.006 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D V A I L ++ + G T ++ +S PEL + V E D+ VG VGS +F Sbjct: 210 DMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIF 269 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+L V + A + + L +V ++ D KI +E + +V MY Sbjct: 270 NILMVLGIAS--AISPMSLISENVIDILVLVGFSVVVWFFARSDRKITRNEGIAMVAMYL 327 Query: 228 FY 229 Y Sbjct: 328 IY 329 >UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 386 Score = 59.3 bits (137), Expect = 2e-07 Identities = 30/101 (29%), Positives = 61/101 (60%), Gaps = 3/101 (2%) Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364 IP HS++ + ++ ++ G Y+++ +T + +L++ ++ G TIL+ T+LPE Sbjct: 235 IPRSTLYHSVHLILGLLALSLSG---YILSHSLTSLATSLSLSTNVLGTTILSIATTLPE 291 Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + ++L K+ G + ++N++GSNTF + LC G+ +L L Sbjct: 292 KLVAILSGKRRQGGIIVANTVGSNTFLLTLCAGILFLAGDL 332 >UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Ca2+/Na+ antiporter - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 313 Score = 59.3 bits (137), Expect = 2e-07 Identities = 30/66 (45%), Positives = 41/66 (62%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + L +P I GLTI+A GTS PEA S+ + QG + +SN IGSN F+IL +G+ Sbjct: 32 IATILKIPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNALAVSNVIGSNIFNILGIIGIC 91 Query: 400 WLVKSL 405 L+K L Sbjct: 92 ALLKEL 97 Score = 54.0 bits (124), Expect = 7e-06 Identities = 26/51 (50%), Positives = 35/51 (68%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 +++ GLTI+A GTSLPE V+S+ K+ + I N IGSN F+IL LGL Sbjct: 203 ETLVGLTIVAIGTSLPELVTSLTALKRDENQLVIGNVIGSNIFNILFVLGL 253 Score = 45.2 bits (102), Expect = 0.003 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Query: 97 YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156 + L+ GS D FV I L I + I G T +A +S+PE ++ + L Sbjct: 15 FAILIKGS---DIFVSGSSNIATILKIPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNAL 71 Query: 157 GVGAVVGSAVFNVLAVPACCAL 178 V V+GS +FN+L + CAL Sbjct: 72 AVSNVIGSNIFNILGIIGICAL 93 Score = 35.5 bits (78), Expect = 2.7 Identities = 17/50 (34%), Positives = 27/50 (54%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 ++ + G T +A +S PEL + E L +G V+GS +FN+L V Sbjct: 201 MSETLVGLTIVAIGTSLPELVTSLTALKRDENQLVIGNVIGSNIFNILFV 250 >UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).; n=1; Takifugu rubripes|Rep: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1). - Takifugu rubripes Length = 900 Score = 58.8 bits (136), Expect = 3e-07 Identities = 27/90 (30%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 FI+CI+ IG ++ ++ I + G T+ + DS+T + +A GTS+P+ S V + + Sbjct: 731 FIVCISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 790 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 I N GSN ++ L +G+ W + ++++ Sbjct: 791 DASIGNVTGSNAVNVFLGIGVAWSIAAIYH 820 Score = 38.7 bits (86), Expect = 0.29 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ++ T MA SS+PE+ ++ V G G+LG +VGSA FN+ + C Sbjct: 121 VSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLC 173 Score = 34.3 bits (75), Expect = 6.2 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 5/55 (9%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398 ++++ LT++A G+S PE + SV V GH G +G + +GS F++ + +GL Sbjct: 119 ETVSNLTLMALGSSAPEILLSV-VEVCGHNFDAGELGPNTIVGSAAFNMFVIIGL 172 >UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family precursor - Psychrobacter sp. PRwf-1 Length = 322 Score = 58.8 bits (136), Expect = 3e-07 Identities = 30/88 (34%), Positives = 50/88 (56%) Query: 318 TFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHG 377 T I+ ++ + + S + W + + + + GLTI+A GTSLPE V+SV ++G Sbjct: 175 TLILGLSLLIASSRAIVWGAVELATLWGMSELLIGLTIVAIGTSLPELVASVAAARRGEH 234 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSL 405 M + N IGSN F+ L +GL ++K + Sbjct: 235 DMALGNVIGSNLFNTLGVVGLAAIIKPM 262 Score = 50.0 bits (114), Expect = 1e-04 Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 2/127 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D F+ + R N+ S + G + +S+PEL ++ + F DL +G GS + Sbjct: 20 DTFIDGATSLAVRFNMPSFLIGVIILGIGTSAPELVVSALAAFAGSPDLALGNAYGSNII 79 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ V AL + +I D + D M+ + L+D + + ++LV+ Sbjct: 80 NITLVLGVTALISPILIRSD--VIRYDLMLLLAVTALAAIQLVDGNLSRLDGIVLVVALV 137 Query: 228 FYILEKI 234 +L +I Sbjct: 138 AVLLIQI 144 Score = 47.2 bits (107), Expect = 8e-04 Identities = 24/65 (36%), Positives = 34/65 (52%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 N+P + G+ IL GTS PE V S L G + + N+ GSN +I L LG+ L+ Sbjct: 34 NMPSFLIGVIILGIGTSAPELVVSALAAFAGSPDLALGNAYGSNIINITLVLGVTALISP 93 Query: 405 LFYPS 409 + S Sbjct: 94 ILIRS 98 Score = 40.3 bits (90), Expect = 0.095 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186 + G T +A +S PEL + E D+ +G V+GS +FN L V A+ + + Sbjct: 207 LIGLTIVAIGTSLPELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIK-PMQHI 265 Query: 187 DWWSVTRDCMMYXXXXXXL-ILTLL----DDKIYWHEALLLVLMYTFY 229 D ++RD MM L IL ++ ++ ++L+L + FY Sbjct: 266 DPQILSRDVMMVGMVSVLLFILAIIAFKRQGEMKHGSGVVLILTFIFY 313 >UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=3; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Stappia aggregata IAM 12614 Length = 337 Score = 58.8 bits (136), Expect = 3e-07 Identities = 27/63 (42%), Positives = 40/63 (63%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + L +P+ + GLTI+A GTS PE V S+ +G G + I N +GSN ++LL LG+P Sbjct: 29 IAQRLGIPNLVIGLTIVAFGTSAPELVISLKAALEGAGGIAIGNVVGSNIANVLLVLGMP 88 Query: 400 WLV 402 L+ Sbjct: 89 ALI 91 Score = 58.4 bits (135), Expect = 3e-07 Identities = 25/71 (35%), Positives = 44/71 (61%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + + V +++ GLT++A GTSLPE ++V+ + HG + I N IGSN F++L +G Sbjct: 213 TSIATSWGVSEAVIGLTVIALGTSLPELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIG 272 Query: 398 LPWLVKSLFYP 408 + ++ + P Sbjct: 273 ITAVIVPIDVP 283 Score = 46.4 bits (105), Expect = 0.001 Identities = 30/92 (32%), Positives = 47/92 (51%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +L +++L L++ + D V I +RL I + + G T +A +S+PEL I+ Sbjct: 1 MLFDYISLAGGLVVLIIAGDVLVRGSVGIAQRLGIPNLVIGLTIVAFGTSAPELVISLKA 60 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 G + +G VVGS + NVL V AL A Sbjct: 61 ALEGAGGIAIGNVVGSNIANVLLVLGMPALIA 92 Score = 39.1 bits (87), Expect = 0.22 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 5/72 (6%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA-- 180 ++ + G T +A +S PEL + G + +G V+GS VFN+LA+ A+ Sbjct: 221 VSEAVIGLTVIALGTSLPELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPI 280 Query: 181 ---GAVIELDWW 189 V++LD W Sbjct: 281 DVPQEVLKLDIW 292 >UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorhabditis|Rep: Sodium-calcium exchanger - Caenorhabditis elegans Length = 880 Score = 58.8 bits (136), Expect = 3e-07 Identities = 36/122 (29%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 282 KISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVG 341 +++ +K+ + P +L L+A IP + + L F++ I IG ++ + I G Sbjct: 676 EVTTMEKVMHYIALPWKL-LFALIPPTDYFNGW--LCFVVAIAMIGLLTAFIGDIAAAFG 732 Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG-ISNSIGSNTFDILLCLGLPW 400 T+ + DS+T LT++A GTSLP+ +S G I N GSN ++ L +G+ W Sbjct: 733 CTVGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAW 792 Query: 401 LV 402 ++ Sbjct: 793 MI 794 Score = 40.7 bits (91), Expect = 0.072 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 ++ T MA SS+PE+ ++ + G G+LG +VGSA FN+ + A C + Sbjct: 130 VSNLTLMALGSSAPEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVCIM 184 >UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio vulnificus Length = 321 Score = 58.4 bits (135), Expect = 3e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 ++ + D + GLTI+A GTSLPE +S+ +G M + N IGSN F+IL +G+ Sbjct: 198 IIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGI 257 Query: 399 PWLVKSLF 406 P ++ F Sbjct: 258 PGILNPSF 265 Score = 49.6 bits (113), Expect = 2e-04 Identities = 26/73 (35%), Positives = 39/73 (53%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 L+L + D V II + ++ + G T +A +S PEL + G E D+ VG Sbjct: 182 LILLPLAADMLVDNAVIIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVG 241 Query: 160 AVVGSAVFNVLAV 172 ++GS VFN+LAV Sbjct: 242 NIIGSNVFNILAV 254 Score = 44.8 bits (101), Expect = 0.004 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +L L L+L D V + + I+ + G T +A SS+PE+ ++ Sbjct: 1 MLEAVALLIVGLILLVWSADKLVFGSAALARNIGISPLVIGMTILAMGSSAPEMMVSATA 60 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208 + D VG V+GS + N+ + AL + ++ V R+ + + Sbjct: 61 ALDGKTDTAVGNVLGSNIANIALILGITALV--RPLSINSAVVRRELPLMIGVTILAGIL 118 Query: 209 LLDDKIYWHEALLLVLMYTFYIL 231 L D + ++E +LL +++T +++ Sbjct: 119 LWDSHLGFYEGVLLFVLFTLFLV 141 Score = 44.0 bits (99), Expect = 0.008 Identities = 22/62 (35%), Positives = 33/62 (53%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + + G+TILA G+S PE + S G + N +GSN +I L LG+ LV+ Sbjct: 33 IGISPLVIGMTILAMGSSAPEMMVSATAALDGKTDTAVGNVLGSNIANIALILGITALVR 92 Query: 404 SL 405 L Sbjct: 93 PL 94 >UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Halothermothrix orenii H 168|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Halothermothrix orenii H 168 Length = 383 Score = 58.4 bits (135), Expect = 3e-07 Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 4/135 (2%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158 FL++GS +PA+EI R+ I I AT +A +S PEL G+L V Sbjct: 245 FLVIGS--SKVLIPAVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAV 302 Query: 159 GAVVGSAVFNVL-AVPACCALFAGAV-IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216 G +VG+ + NVL V + ++ AG + + +++ + M+ L +++I Sbjct: 303 GNIVGADILNVLFVVGSAASVTAGGLNVPANFYRLQIPTMVIILVTFRLFSRGRNEEITK 362 Query: 217 HEALLLVLMYTFYIL 231 E ++L L+Y Y++ Sbjct: 363 KEGIVLFLLYVIYLI 377 Score = 54.8 bits (126), Expect = 4e-06 Identities = 22/72 (30%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 IGS L+ + + + +P+SI T++A GTSLPE ++++ ++GHG + + N + Sbjct: 248 IGSSKVLIP-AVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAVGNIV 306 Query: 386 GSNTFDILLCLG 397 G++ ++L +G Sbjct: 307 GADILNVLFVVG 318 Score = 48.8 bits (111), Expect = 3e-04 Identities = 26/62 (41%), Positives = 37/62 (59%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L VP I G TI++ GT+LPEA SVL G+ + + N++GS D L +G+ L+ Sbjct: 73 LGVPKVIIGATIVSLGTTLPEAAVSVLAAINGNPDLALGNAVGSIIADTGLIIGVAALLG 132 Query: 404 SL 405 SL Sbjct: 133 SL 134 >UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Marinobacter sp. ELB17|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Marinobacter sp. ELB17 Length = 328 Score = 58.4 bits (135), Expect = 3e-07 Identities = 27/65 (41%), Positives = 41/65 (63%) Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 G L VP+++ G+T++A GTSLPE +SV ++G M I +GSN F+IL + + Sbjct: 200 GFALGVPEAVIGMTVIAFGTSLPELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITA 259 Query: 401 LVKSL 405 +VK L Sbjct: 260 VVKPL 264 Score = 41.9 bits (94), Expect = 0.031 Identities = 21/65 (32%), Positives = 35/65 (53%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L + + G T +A +S PEL + + D+ +G +VGS +FN+L+V A A+ Sbjct: 203 LGVPEAVIGMTVIAFGTSLPELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITAVVK 262 Query: 181 GAVIE 185 VI+ Sbjct: 263 PLVID 267 Score = 41.1 bits (92), Expect = 0.054 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 5/110 (4%) Query: 76 DGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAA 135 DGLT +Q I L L+ G D + + I ER ++ AT +A Sbjct: 2 DGLTTYQL--AVIALGAIFFGVWLLVKGG---DLTIDSAVRIAERSGLSKMFIAATIVAF 56 Query: 136 ASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 +S+PELF + + VG V+GS + NVL V A+ A V + Sbjct: 57 GTSAPELFTSVNANISGFAGISVGNVIGSNIANVLMVIGISAMIAPIVFD 106 Score = 39.9 bits (89), Expect = 0.13 Identities = 18/54 (33%), Positives = 31/54 (57%) Query: 354 TILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 TI+A GTS PE +SV G + + N IGSN ++L+ +G+ ++ + + Sbjct: 52 TIVAFGTSAPELFTSVNANISGFAGISVGNVIGSNIANVLMVIGISAMIAPIVF 105 >UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenorhabditis|Rep: Na/ca exchangers protein 8 - Caenorhabditis elegans Length = 703 Score = 58.4 bits (135), Expect = 3e-07 Identities = 27/95 (28%), Positives = 53/95 (55%) Query: 310 HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369 H+ L F+M I WI + + + ++T+VG + + GLT+++ + + V+ + Sbjct: 540 HKEVYSYLGFLMSIAWIYATANEIISVMTMVGVVTGLSQELLGLTVMSWSDCIGDIVADI 599 Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 V KQG+ M ++ +IG F++L+ GLP+ + S Sbjct: 600 AVIKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIAS 634 Score = 51.2 bits (117), Expect = 5e-05 Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 8/152 (5%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---I 144 I++ ++ F+++ ++ +D+F P+I I L ++ IAG TF+A + +P++F Sbjct: 105 IIVGIIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSIS 164 Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204 + + T + L +G + G+++F V V +F + ++ RD + Y Sbjct: 165 SVLSTPKPKAALALGDLFGTSIF-VTTVVLAIIIFTKS-FKVAIIPTLRDLIFYMITLAF 222 Query: 205 LILTLLD-DKI-YWHEALLLVLMYTFYILEKI 234 + L DKI W A L + Y Y+L I Sbjct: 223 ITFCFLKFDKIEVWMPATFLGI-YAVYLLTVI 253 >UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacteria|Rep: Na+/Ca2+-exchanging protein - Salinibacter ruber (strain DSM 13855) Length = 350 Score = 58.0 bits (134), Expect = 4e-07 Identities = 24/62 (38%), Positives = 40/62 (64%) Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 GD P + G+T++AAGTS+P+A S+ ++ G+ ++N +GSN FD+L+C+ Sbjct: 214 GDIFGTPSFLWGITVVAAGTSVPDAFVSIRASRAGNPVTSVANVLGSNIFDLLVCIPAAA 273 Query: 401 LV 402 LV Sbjct: 274 LV 275 Score = 46.8 bits (106), Expect = 0.001 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVI 184 + G+ +A SS PEL V + GD LGV AVVGSA+FN+L +PA L+A + Sbjct: 45 VQGSIVLAVGSSFPELS-TAVLSAALHGDFELGVAAVVGSALFNILMIPALAGLWAEERL 103 Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215 E + ++ Y L+L IY Sbjct: 104 ESTRDLIYKETQFYLISIVVLLLMFSFAVIY 134 Score = 34.3 bits (75), Expect = 6.2 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401 +P + G +LA G+S PE ++VL G +G++ +GS F+IL+ L L Sbjct: 41 LPPLVQGSIVLAVGSSFPELSTAVLSAALHGDFELGVAAVVGSALFNILMIPALAGL 97 >UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein precursor; n=11; Proteobacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein precursor - Azotobacter vinelandii AvOP Length = 360 Score = 58.0 bits (134), Expect = 4e-07 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 9/93 (9%) Query: 316 PLTFIMCITWIGSVSYLVAWIITVVGDT------LNVPDSITGLTILAAGTSLPEAVSSV 369 PLTFI C+ I ++ L+A +V +P I GLT++A GTS PE SV Sbjct: 3 PLTFI-CL--IAGLALLIAGAEALVRGAARLAARFGIPPLIIGLTVVAFGTSAPEMAVSV 59 Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 G G + + N+IGSN F++L+ LGL LV Sbjct: 60 RSASGGQGDIAVGNAIGSNIFNVLMILGLSALV 92 Score = 54.4 bits (125), Expect = 5e-06 Identities = 49/154 (31%), Positives = 69/154 (44%), Gaps = 3/154 (1%) Query: 79 TRFQRQ-HGFILLHCFLALYCFLLLGSVC-EDYFVPAIEIICERLNIASDIAGATFMAAA 136 T F R+ G + L LAL L V D + A + L ++ G T +AA Sbjct: 162 TEFGRKPEGRLALPGHLALVALGLAMLVWGSDLLIDATVTLARALGLSELAIGLTMVAAG 221 Query: 137 SSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDC- 195 +S PEL + V E D+ VG +VGS +FN+LAV AL + A IE+ ++ D Sbjct: 222 TSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALVSPAPIEVSPNALAFDYP 281 Query: 196 MMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 +M L + L +I E LL Y Y Sbjct: 282 VMIAAAAACLPIFLTGYRIGRWEGLLFFGYYLAY 315 Score = 52.4 bits (120), Expect = 2e-05 Identities = 25/59 (42%), Positives = 38/59 (64%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L + + GLT++AAGTSLPE +S++ +G + + N +GSN F++L LGL LV Sbjct: 206 LGLSELAIGLTMVAAGTSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALV 264 Score = 43.2 bits (97), Expect = 0.013 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 92 CFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV 151 C +A L+ G+ + V + R I I G T +A +S+PE+ ++ Sbjct: 8 CLIAGLALLIAGA---EALVRGAARLAARFGIPPLIIGLTVVAFGTSAPEMAVSVRSASG 64 Query: 152 TEGDLGVGAVVGSAVFNVLAVPACCAL 178 +GD+ VG +GS +FNVL + AL Sbjct: 65 GQGDIAVGNAIGSNIFNVLMILGLSAL 91 >UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Reinekea sp. MED297|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Reinekea sp. MED297 Length = 321 Score = 58.0 bits (134), Expect = 4e-07 Identities = 26/71 (36%), Positives = 41/71 (57%) Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 ++ W + D + +++ G TI+A GTSLPE +SV + H + I N +GSN F+ Sbjct: 188 VLVWGAVGIADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFN 247 Query: 392 ILLCLGLPWLV 402 IL L +P L+ Sbjct: 248 ILAVLSVPGLI 258 Score = 50.8 bits (116), Expect = 7e-05 Identities = 24/63 (38%), Positives = 39/63 (61%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + L VP I G+TI++ GTS PE ++++ +G + + N+IGSN +I L LG+ Sbjct: 29 LANNLGVPHLIIGVTIVSLGTSAPEIIAAIFAALEGRIELAMGNAIGSNVANIGLVLGIT 88 Query: 400 WLV 402 LV Sbjct: 89 ALV 91 Score = 45.2 bits (102), Expect = 0.003 Identities = 22/71 (30%), Positives = 36/71 (50%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + I+ + GAT +A +S PEL + D+ +G V+GS +FN+LAV + Sbjct: 196 IADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFNILAVLSVP 255 Query: 177 ALFAGAVIELD 187 L A + + Sbjct: 256 GLIAPGAFDAE 266 Score = 35.1 bits (77), Expect = 3.6 Identities = 23/87 (26%), Positives = 37/87 (42%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 LA+ L+ + D FV + L + I G T ++ +S+PE+ Sbjct: 6 LAILVGLIFLVLSADRFVAGAAALANNLGVPHLIIGVTIVSLGTSAPEIIAAIFAALEGR 65 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFA 180 +L +G +GS V N+ V AL A Sbjct: 66 IELAMGNAIGSNVANIGLVLGITALVA 92 >UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; Chloroflexus|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Chloroflexus aurantiacus J-10-fl Length = 361 Score = 57.6 bits (133), Expect = 6e-07 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 5/137 (3%) Query: 93 FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 F+A L+LG+ D V + L ++S I G T +A +SSPE+ ++ F Sbjct: 6 FIAGIVLLVLGA---DLLVRGAASLAAGLGVSSLIIGLTVVAVGTSSPEIAVSLQAAFDG 62 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 +G + +G +VGS + NV+ + A+F + +D RD + L LD Sbjct: 63 QGAITLGNIVGSNIANVMLILGVAAMFGS--LPVDQQIFRRDLPIMIGASLLTFLLALDR 120 Query: 213 KIYWHEALLLVLMYTFY 229 + W + ++++L T Y Sbjct: 121 TLSWVDGMIMLLALTGY 137 Score = 49.2 bits (112), Expect = 2e-04 Identities = 24/51 (47%), Positives = 33/51 (64%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 V + I GLTI+A GTSLPE +SV+ +G + + N IGSN ++LL L Sbjct: 198 VSELIIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLVL 248 Score = 48.0 bits (109), Expect = 5e-04 Identities = 24/62 (38%), Positives = 35/62 (56%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L V I GLT++A GTS PE S+ G G + + N +GSN +++L LG+ + Sbjct: 31 LGVSSLIIGLTVVAVGTSSPEIAVSLQAAFDGQGAITLGNIVGSNIANVMLILGVAAMFG 90 Query: 404 SL 405 SL Sbjct: 91 SL 92 Score = 35.9 bits (79), Expect = 2.0 Identities = 17/46 (36%), Positives = 26/46 (56%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I G T +A +S PE+ + + E D+ VG V+GS + N+L V Sbjct: 202 IIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLV 247 >UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobacteriales|Rep: Sodium/calcium exchanger - Robiginitalea biformata HTCC2501 Length = 315 Score = 57.6 bits (133), Expect = 6e-07 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 6/98 (6%) Query: 305 IPDCRHRHSIYPLTFIMCI----TWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360 +P R +Y + ++ + W GS LV ++ D L V D + G+T+++ GT Sbjct: 158 LPVARRPLPLYKMALLLLVGGVALWAGS-ELLVRGATSLAAD-LGVSDRVIGITVVSVGT 215 Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 S+PE +SV+ + M + N IGSN F++L LGL Sbjct: 216 SIPELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGL 253 Score = 45.2 bits (102), Expect = 0.003 Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 6/114 (5%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L ++ + G T ++ +S PEL + + E + VG ++GS +FN+LAV A+ A Sbjct: 199 LGVSDRVIGITVVSVGTSIPELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLTAILA 258 Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLL----DDKIYWHEALLLVLMYTFYI 230 + LD +TRD + + L+L L+ ++ W + ++L+ Y ++ Sbjct: 259 PVPV-LDDRLLTRD-VFWMLGISFLVLPLVFFPKGLRLGWRDGIVLLACYGAFL 310 Score = 42.7 bits (96), Expect = 0.018 Identities = 18/59 (30%), Positives = 34/59 (57%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L++P + G+T+++ TS PE + S G+ + + N +GSNT ++ L L + L+ Sbjct: 35 LSIPKIVIGMTVVSLATSAPELIVSAQAALAGYPDLALGNVVGSNTANLGLVLAVTLLI 93 Score = 36.7 bits (81), Expect = 1.2 Identities = 21/59 (35%), Positives = 31/59 (52%) Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 RL+I + G T ++ A+S+PEL ++ DL +G VVGS N+ V A L Sbjct: 34 RLSIPKIVIGMTVVSLATSAPELIVSAQAALAGYPDLALGNVVGSNTANLGLVLAVTLL 92 >UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium exchanger), member 1 variant; n=24; Bilateria|Rep: Solute carrier family 8 (Sodium/calcium exchanger), member 1 variant - Homo sapiens (Human) Length = 411 Score = 57.6 bits (133), Expect = 6e-07 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ + Sbjct: 242 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 301 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417 I N GSN ++ L +G+ W + ++++ + E V+ Sbjct: 302 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 341 >UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1); n=185; Euteleostomi|Rep: Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human) Length = 973 Score = 57.6 bits (133), Expect = 6e-07 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ + Sbjct: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417 I N GSN ++ L +G+ W + ++++ + E V+ Sbjct: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 903 Score = 43.6 bits (98), Expect = 0.010 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186 >UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: sodium/calcium exchanger protein - Entamoeba histolytica HM-1:IMSS Length = 510 Score = 57.2 bits (132), Expect = 8e-07 Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F++ + +I + + ++ +G + + SI GLT+L G S+ + VS+V+V+ QG+ Sbjct: 354 FVISVLYIYIFASELVALLQSIGVAMKIDSSILGLTVLCWGNSVGDFVSNVIVSSQGYSE 413 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKS-LFYPSTPENHWVTDLYF 421 MGI S G F++L+ LG L +S L +P + + L+F Sbjct: 414 MGIIASYGGPCFNLLIGLGGGVLARSILHFPKSQQIVMTDSLFF 457 Score = 55.2 bits (127), Expect = 3e-06 Identities = 53/241 (21%), Positives = 107/241 (44%), Gaps = 22/241 (9%) Query: 87 FILLHCFLA--LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFI 144 +I+L C + + F LL D+FVP + I+ + L++++D+AG T +A + +P++F Sbjct: 53 WIVLVCMVIGIIIIFYLLSVSSSDHFVPILTILSKHLSMSADLAGITILAIGNGAPDVFS 112 Query: 145 NCVGTFVT-EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXX 203 V + T + +L V+GS F + A L I++ ++ + Y Sbjct: 113 TFVAIYNTGDVELATAEVIGSGCFVSSIIVASIVLLGKEDIKMP-ETLIHNISCYILALL 171 Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI-----LEKINPL---------DASQRMTPRSVQ 249 + + +++ +L+Y Y+ + K PL + ++ ++ Sbjct: 172 FVYFICTTGSVSIIHSIIFILIYILYVCFIGYITKNKPLIKISEQLDSENKTKLIDNTLN 231 Query: 250 NGD--LERGIEMTRRHDSTGSDISTSSVWSFPGD-KISFW-KKLFWVLTWPIRLILWATI 305 N D L E T +++ SD +S ++ K++ W K+ +L+ P R I+ T Sbjct: 232 NIDEELNSSNECTTLNNNISSDKGFTSQYNILEQIKLTNWFNKILLILSIPFRFIMEFTT 291 Query: 306 P 306 P Sbjct: 292 P 292 >UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family - Thermosipho melanesiensis BI429 Length = 311 Score = 57.2 bits (132), Expect = 8e-07 Identities = 34/118 (28%), Positives = 63/118 (53%) Query: 289 LFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348 L++++T ++ + +++ I L ++ I I L + + +L + + Sbjct: 141 LYYLITSAKNVVEEEFKDEVKYKTHIALLLIVVGIVGIWLGGDLTIGNVIKLAKSLGLSE 200 Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406 + GLTI+A GTSLPE V S++ T + + + N +GSN F+IL LG+ LV +L+ Sbjct: 201 TFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVSSLVGNLY 258 Score = 56.4 bits (130), Expect = 1e-06 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + + L ++ G T +A +S PE+ ++ + T E D+ VG +VGS +FN+L + Sbjct: 192 LAKSLGLSETFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVS 251 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILT-LLDDKIYWHEALLLVLMYTFYILE 232 +L +++ + T D ++ L T LL KI E + + +Y FYI + Sbjct: 252 SLVGNLYVDVQ--NFTIDLIIMNLFVFILFFTSLLRKKIGKVEGIFFLTIYVFYIYQ 306 Score = 54.4 bits (125), Expect = 5e-06 Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 3/74 (4%) Query: 335 WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 W++ T + L V + GL+++A GTSLPE V+S++ +GH ++ ISN +GSN + Sbjct: 21 WLVDGATSIALNLGVSKIVVGLSVVAFGTSLPELVASLVSVIKGHSSVSISNVVGSNIAN 80 Query: 392 ILLCLGLPWLVKSL 405 I + L L L S+ Sbjct: 81 IAIALALSSLFVSI 94 Score = 41.9 bits (94), Expect = 0.031 Identities = 27/127 (21%), Positives = 56/127 (44%), Gaps = 4/127 (3%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V I L ++ + G + +A +S PEL + V + + VVGS + Sbjct: 20 DWLVDGATSIALNLGVSKIVVGLSVVAFGTSLPELVASLVSVIKGHSSVSISNVVGSNIA 79 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALL---LVL 224 N+ A +LF I+ + M+ +L + D+ + W+ ++ L++ Sbjct: 80 NIAIALALSSLFVSINIKKNTIKAEMPFMIISTIVFT-VLFIKDNSLTWNYGVVFISLLV 138 Query: 225 MYTFYIL 231 +Y +Y++ Sbjct: 139 IYLYYLI 145 >UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter, CaCA family protein precursor - Psychromonas ingrahamii (strain 37) Length = 326 Score = 57.2 bits (132), Expect = 8e-07 Identities = 31/83 (37%), Positives = 46/83 (55%) Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 I+ I + + S L+ W V V D I GLTI+A GTSLPE +++ ++ + Sbjct: 180 IIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDL 239 Query: 380 GISNSIGSNTFDILLCLGLPWLV 402 + N IGSN F+IL + LP L+ Sbjct: 240 AVGNIIGSNIFNILGVMALPGLI 262 Score = 46.8 bits (106), Expect = 0.001 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 4/66 (6%) Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 + ++ I G+ I+ GTS PE + S + QG+ + I N+IGSN +I L LG V Sbjct: 35 SFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTGLSIGNAIGSNITNIGLMLG----V 90 Query: 403 KSLFYP 408 ++FYP Sbjct: 91 TAIFYP 96 Score = 39.5 bits (88), Expect = 0.17 Identities = 20/48 (41%), Positives = 26/48 (54%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174 I G T +A +S PEL E DL VG ++GS +FN+L V A Sbjct: 210 IIGLTIVAIGTSLPELAATIAAARKKEFDLAVGNIIGSNIFNILGVMA 257 >UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; Mycobacterium|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 335 Score = 57.2 bits (132), Expect = 8e-07 Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364 +PD + +T + + +LV + + + V D++ GLTI+A GTS PE Sbjct: 179 MPDTGSLVRYFAMTIVGITVVVVGADWLVEGAVGIARE-FGVSDALIGLTIVAIGTSAPE 237 Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416 V++++ T +G + I N +GS+ ++I+L LG LV + P W+ Sbjct: 238 LVTTIVSTVRGERDIAIGNLLGSSVYNIVLILGATCLVPADGLPLNSSLVWI 289 Score = 50.4 bits (115), Expect = 9e-05 Identities = 21/62 (33%), Positives = 36/62 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + + G+T+++ GTSLPE V +G G + + N G+NT ++L LGL L++ Sbjct: 33 MGISPIVVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLSALLR 92 Query: 404 SL 405 L Sbjct: 93 PL 94 Score = 44.4 bits (100), Expect = 0.006 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V I ++ + G T +A +S+PEL V T E D+ +G ++GS+V+ Sbjct: 204 DWLVEGAVGIAREFGVSDALIGLTIVAIGTSAPELVTTIVSTVRGERDIAIGNLLGSSVY 263 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD-KIYWHEALLLVLMY 226 N++ + L + L+ V D + LI +++ E +V+ Y Sbjct: 264 NIVLILGATCLVPADGLPLNSSLVWIDIPVMVVATLLLIPVFFSGRRVHRAEGGAMVVAY 323 Query: 227 TFYI 230 Y+ Sbjct: 324 LAYL 327 Score = 34.3 bits (75), Expect = 6.2 Identities = 18/69 (26%), Positives = 31/69 (44%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + R+ I+ + G T ++ +S PEL + G L VG + G+ N+L + Sbjct: 29 MASRMGISPIVVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLS 88 Query: 177 ALFAGAVIE 185 AL I+ Sbjct: 89 ALLRPLAIQ 97 >UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 974 Score = 57.2 bits (132), Expect = 8e-07 Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 6/146 (4%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 FIL F+ + F +G D+F P + + L + AG TF+A + SP++F Sbjct: 78 FILFLLFILAFLFSFIGISAADFFCPNLSTVAAYLGLNESTAGVTFLAFGNGSPDVF--S 135 Query: 147 VGTFVTEGDLG--VGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204 + ++ G LG VG ++G+A F V V A + + + RD + + Sbjct: 136 TFSAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIRPFHVPKN--AFRRDVIFFTIAVLM 193 Query: 205 LILTLLDDKIYWHEALLLVLMYTFYI 230 LI+ L D + + E+ +V +Y Y+ Sbjct: 194 LIVALHDGHLTFAESGSMVGLYVVYV 219 Score = 48.0 bits (109), Expect = 5e-04 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FI + WI +++ V +++ +G+ L + D+I GLTI A G SL + V++V V Q Sbjct: 819 FICSMMWIAAIADEVVDVLSTLGEILGLSDAIIGLTIFAVGNSLADLVANVTVA-QFAPA 877 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418 M + G ++LL +G LF S+P + + D Sbjct: 878 MAYAACFGGPMLNLLLGVGGSGTYHLLF--SSPHSPIIVD 915 Score = 33.9 bits (74), Expect = 8.2 Identities = 24/111 (21%), Positives = 47/111 (42%), Gaps = 4/111 (3%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 ++ L F+ I + + + TV L + +S G+T LA G P+ S+ Sbjct: 83 LFILAFLFSFIGISAADFFCPNLSTVAA-YLGLNESTAGVTFLAFGNGSPDVFSTFSAMS 141 Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRI 424 G + + IG+ +F + + +G ++ P+N + D+ F I Sbjct: 142 SGTLGLAVGELIGAASFIVSIVVGSIAFIRPF---HVPKNAFRRDVIFFTI 189 >UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 704 Score = 57.2 bits (132), Expect = 8e-07 Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 2/135 (1%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155 + CF+ +G +Y P + I + L + +AG T +A +SSP++F + Sbjct: 100 ILCFISVGITASEYLCPNLYTISQFLKLPDTLAGLTLLAFGNSSPDVFGTYHAIGSNSLN 159 Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215 L + ++G+++F + V A+ + + + RDCMMY ++++L+ ++ Sbjct: 160 LAIAELIGASLFIMTVVVGTIAIIEPFNVPKNLF--IRDCMMYIMVFALVVISLIIGELT 217 Query: 216 WHEALLLVLMYTFYI 230 +LLV Y Y+ Sbjct: 218 SIICILLVSCYIIYV 232 Score = 42.7 bits (96), Expect = 0.018 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 8/110 (7%) Query: 313 SIYPLTF--IMCITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368 SI PLT I+C +G + YL + T+ L +PD++ GLT+LA G S P+ + Sbjct: 91 SILPLTICLILCFISVGITASEYLCPNLYTI-SQFLKLPDTLAGLTLLAFGNSSPDVFGT 149 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418 + I+ IG++ F + + +G +++ + P+N ++ D Sbjct: 150 YHAIGSNSLNLAIAELIGASLFIMTVVVGTIAIIEPF---NVPKNLFIRD 196 Score = 39.1 bits (87), Expect = 0.22 Identities = 19/68 (27%), Positives = 33/68 (48%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FI+ I WI +S + I+ ++ + + I GLTI A G S+ + +S+ + G Sbjct: 555 FILSICWISLISDEIINILHIISIIYQLSEDILGLTIFALGNSIGDFISNYTIAMMGKPI 614 Query: 379 MGISNSIG 386 M + G Sbjct: 615 MAFTACFG 622 >UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2; Methanosarcinaceae|Rep: Sodium/calcium exchanger protein - Methanosarcina acetivorans Length = 315 Score = 57.2 bits (132), Expect = 8e-07 Identities = 28/85 (32%), Positives = 51/85 (60%), Gaps = 5/85 (5%) Query: 326 IGSVSYLVAWIITV-----VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380 +GS+S ++ I V + + + +P+ I LT +A GTSLPE V+++ ++GH + Sbjct: 176 LGSLSVVIGSRILVDSGIKIAEWIGIPEVIIALTAVAIGTSLPELVTAIASLRKGHQDLS 235 Query: 381 ISNSIGSNTFDILLCLGLPWLVKSL 405 I N +G+NT D+ + LG+ ++ L Sbjct: 236 IGNILGANTMDVAMILGVSSQIRVL 260 Score = 43.6 bits (98), Expect = 0.010 Identities = 31/142 (21%), Positives = 64/142 (45%), Gaps = 3/142 (2%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 LL FL L ++ S D+F+ A I + I + GAT ++ A+++PE ++ Sbjct: 3 LLLIFLFLLSLAMI-SKGSDWFIEAAVAISNKSGIPKMLIGATIVSFATTAPEFAVSATA 61 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208 ++ D+ +G VGS + N V ++ D + + M+ LI+ Sbjct: 62 AYLGHTDVTIGNAVGSVICNTGLVLGSIIAVKAIPMKDDTFPIKSGLML--LSGIILIIV 119 Query: 209 LLDDKIYWHEALLLVLMYTFYI 230 D + + ++L+L++ ++ Sbjct: 120 SRDGNVNRLDGIILLLVFFAFL 141 Score = 35.9 bits (79), Expect = 2.0 Identities = 22/87 (25%), Positives = 38/87 (43%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 F++ + I S + + +P + G TI++ T+ PE S GH Sbjct: 9 FLLSLAMISKGSDWFIEAAVAISNKSGIPKMLIGATIVSFATTAPEFAVSATAAYLGHTD 68 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405 + I N++GS + L LG VK++ Sbjct: 69 VTIGNAVGSVICNTGLVLGSIIAVKAI 95 >UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; Methanosarcina mazei|Rep: Sodium-calcium exchanger protein - Methanosarcina mazei (Methanosarcina frisia) Length = 392 Score = 57.2 bits (132), Expect = 8e-07 Identities = 27/67 (40%), Positives = 42/67 (62%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L VP++I G++++A GTSLPE + +V + G+ ++ + N IGSN + LL LG LV+ Sbjct: 277 LEVPETIIGISLVAVGTSLPELMVTVSAARNGYASIALGNVIGSNITNTLLILGCTGLVQ 336 Query: 404 SLFYPST 410 L T Sbjct: 337 PLMVTGT 343 Score = 50.8 bits (116), Expect = 7e-05 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 2/124 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + I +R ++ I G T ++ +S PE + +F + +G V+GS + Sbjct: 21 DLFVTSSSWIAKRFGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGNVLGSNIA 80 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ + + AL + ++ + + RD + +L ++D +I EA + +L+Y Sbjct: 81 NIGLIVSTAALLSN--VKTEELMLRRDGYIMLFSVFLFLLFVVDFRISRFEAFIFLLLYF 138 Query: 228 FYIL 231 YIL Sbjct: 139 VYIL 142 Score = 39.5 bits (88), Expect = 0.17 Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 YF+ L + I G + +A +S PEL + + +G V+GS + N Sbjct: 265 YFIDKSIFFALLLEVPETIIGISLVAVGTSLPELMVTVSAARNGYASIALGNVIGSNITN 324 Query: 169 VLAVPACCALFAGAVIE-LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 L + C L ++ + +T +++ I T +I HE L+L L+Y+ Sbjct: 325 TLLILGCTGLVQPLMVTGTAVYYITPFMLVFSLLLLLFIRT--GWRIKRHEGLILFLLYS 382 Query: 228 FYIL 231 +++ Sbjct: 383 GFMV 386 Score = 36.7 bits (81), Expect = 1.2 Identities = 20/66 (30%), Positives = 36/66 (54%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + V + I GLT+++ GTS+PE SS+ + + + I N +GSN +I L + Sbjct: 30 IAKRFGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGNVLGSNIANIGLIVSTA 89 Query: 400 WLVKSL 405 L+ ++ Sbjct: 90 ALLSNV 95 >UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+ antiporter, CaCA family precursor - Alkalilimnicola ehrlichei (strain MLHE-1) Length = 327 Score = 56.8 bits (131), Expect = 1e-06 Identities = 25/64 (39%), Positives = 39/64 (60%) Query: 335 WIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394 W T + + V +++ GLT++A GTSLPE + + ++ G + I N IGSN F++L Sbjct: 197 WAATGLAERAGVAETVVGLTLVAVGTSLPELATCLAAARRSQGDIAIGNIIGSNIFNLLG 256 Query: 395 CLGL 398 LGL Sbjct: 257 VLGL 260 Score = 48.0 bits (109), Expect = 5e-04 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 8/118 (6%) Query: 68 AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127 A + P D TR R LL L L L+ V A + ER +A + Sbjct: 161 APVNGLPEDAPTRLPRA----LLWLLLGLVVLLISAQTA----VWAATGLAERAGVAETV 212 Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 G T +A +S PEL ++GD+ +G ++GS +FN+L V A +E Sbjct: 213 VGLTLVAVGTSLPELATCLAAARRSQGDIAIGNIIGSNIFNLLGVLGLAATLRPVALE 270 Score = 44.4 bits (100), Expect = 0.006 Identities = 25/62 (40%), Positives = 34/62 (54%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + + GLTI+A GTS PE + S L G + + N+IGSN ++ L LGL L Sbjct: 33 LGLSPLLVGLTIVAFGTSAPELLVSALAALAGSPGLAVGNAIGSNIANMGLILGLTALFA 92 Query: 404 SL 405 L Sbjct: 93 PL 94 Score = 40.7 bits (91), Expect = 0.072 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 +LL L F LL + D FV L ++ + G T +A +S+PEL ++ + Sbjct: 1 MLLQIILLGLSFALL-AWSADRFVLGASATAALLGLSPLLVGLTIVAFGTSAPELLVSAL 59 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 L VG +GS + N+ + ALFA +I Sbjct: 60 AALAGSPGLAVGNAIGSNIANMGLILGLTALFAPLLI 96 >UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+ antiporter, CaCA family - Alkaliphilus metalliredigens QYMF Length = 334 Score = 56.8 bits (131), Expect = 1e-06 Identities = 26/82 (31%), Positives = 48/82 (58%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 + FI+ +I + L+ ++ + L VP+ + LT++A GTSLPE +++ +GH Sbjct: 176 IMFIVGAVFIALGARLLVNNGVIIANILGVPEQVVSLTLIALGTSLPELTTAISSVVKGH 235 Query: 377 GTMGISNSIGSNTFDILLCLGL 398 + + N +G+N DI++ LGL Sbjct: 236 QGISVGNILGANILDIVMVLGL 257 Score = 55.2 bits (127), Expect = 3e-06 Identities = 34/150 (22%), Positives = 72/150 (48%), Gaps = 3/150 (2%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+FV + + + + + + GAT ++ A++ PEL ++ + T D+ +G V+GS + Sbjct: 22 DWFVESAVWVAKVTGVPNVLIGATIVSIATTLPELLVSVIATQQHYYDVAIGNVIGSMIC 81 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 NV + LF+ + +++ M+ ++ L D I E ++++T Sbjct: 82 NVGLILGLTTLFSPIKLNRSGFAIRGFFML--GSTALMLFFLRDRMISPREGTWFIVLFT 139 Query: 228 FYILEKINPLDASQRMTPRSV-QNGDLERG 256 YIL + + +Q+ P + Q D+ +G Sbjct: 140 IYILINLQEFNKNQKRVPHVLNQEQDVPQG 169 Score = 46.0 bits (104), Expect = 0.002 Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 4/67 (5%) Query: 335 WIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394 W+ V G VP+ + G TI++ T+LPE + SV+ T+Q + + I N IGS ++ L Sbjct: 30 WVAKVTG----VPNVLIGATIVSIATTLPELLVSVIATQQHYYDVAIGNVIGSMICNVGL 85 Query: 395 CLGLPWL 401 LGL L Sbjct: 86 ILGLTTL 92 >UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor (Sorghum) (Sorghum vulgare) Length = 573 Score = 56.8 bits (131), Expect = 1e-06 Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 20/229 (8%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE-GDLG 157 F LLG +YF ++E + L + +AG T ++ + +P++F + V + G +G Sbjct: 120 FYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVSFASGDGGGVG 179 Query: 158 VGAVVGSAVFNVLAVPACCALFAGAV---IELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214 + + +G A+F V AL G + ++W RD L+ L++ I Sbjct: 180 LSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDLCFLLLALCYLLAVLVNGVI 239 Query: 215 YWHEALLLVLMYTFYIL---------EKINPLDASQRMTPRSVQNGDLERGIEMTRRHDS 265 A+ V +Y Y++ EK P+D S +GD E + H Sbjct: 240 TVWVAVSFVSLYVGYVVLVWTSHCCAEKGKPVDESLSAPLLLDDDGD-EDDVPSLPSHSK 298 Query: 266 TGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPD-CRHRHS 313 T SS + G + W L L P+ L TIPD HR S Sbjct: 299 T---TEASSTATSRGRAMLHW--LAGALCMPLYLPRRLTIPDIAGHRWS 342 Score = 38.3 bits (85), Expect = 0.38 Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ---G 375 F+M + W +++ + ++ +G + + S+ G+T+LA G SL + VS+V + G Sbjct: 416 FVMSVLWAYTLARELVALLVSIGYVVGIKPSVLGVTVLAWGDSLGDLVSNVAMAVHGGAG 475 Query: 376 HGTMGISNSIGSNTFDILLCLGL 398 +S F+ ++ LGL Sbjct: 476 GAQTAVSGCYAGPLFNTVVGLGL 498 Score = 34.3 bits (75), Expect = 6.2 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 1/48 (2%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH-GTMGISNSIGSNTF 390 L +P ++ G+T+L+ G P+ +SV+ G G +G+S+++G F Sbjct: 142 LRLPPAVAGVTLLSLGNGAPDVFASVVSFASGDGGGVGLSSALGGALF 189 >UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome shotgun sequence; n=10; Clupeocephala|Rep: Chromosome 10 SCAF15123, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1007 Score = 56.4 bits (130), Expect = 1e-06 Identities = 28/96 (29%), Positives = 52/96 (54%), Gaps = 1/96 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 FI+ I IG ++ ++ + + G T+ + DS+T + +A GTS+P+ S V + + Sbjct: 796 FIVSIIIIGLLTAVIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDMFASKVSAVQDAYA 855 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413 I N GSN ++ L +G+ W V ++++ EN Sbjct: 856 DASIGNVTGSNAVNVFLGIGMAWSVAAIYWNMKGEN 891 Score = 38.3 bits (85), Expect = 0.38 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ++ T MA SS+PE+ ++ + G G+LG +VGSA FN+ + C Sbjct: 97 VSNLTLMALGSSAPEILLSVIEVCGHDFKPGELGPATIVGSAAFNMFVIIGLC 149 Score = 33.9 bits (74), Expect = 8.2 Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398 ++++ LT++A G+S PE + SV + GH G +G + +GS F++ + +GL Sbjct: 95 ETVSNLTLMALGSSAPEILLSV-IEVCGHDFKPGELGPATIVGSAAFNMFVIIGL 148 >UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep: Ca2+/Na+ antiporter - Idiomarina loihiensis Length = 325 Score = 56.4 bits (130), Expect = 1e-06 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S + W + +L V D + GLT++A GTSLPE S++ T++ + + N IGSN Sbjct: 188 SRALVWGAVNIAVSLGVSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNM 247 Query: 390 FDILLCLGLPWLVKSL-FYPSTPENHWV 416 F+ L +G+ ++ + P WV Sbjct: 248 FNTLAVVGIAGAIEPVSLEPLVLSRDWV 275 Score = 45.2 bits (102), Expect = 0.003 Identities = 21/55 (38%), Positives = 32/55 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 L + + G+ I+ GTS PE V S L + QG+ + + N+ GSN +I L LG+ Sbjct: 33 LGMAPLVIGMVIIGFGTSAPEMVVSALASMQGNPALALGNAYGSNITNIALVLGI 87 Score = 42.3 bits (95), Expect = 0.023 Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 13/125 (10%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I L ++ + G T +A +S PEL T E DL +G V+GS +FN LAV Sbjct: 198 IAVSLGVSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNMFNTLAVVG-- 255 Query: 177 ALFAGAV--IELDWWSVTRDCMMYXXXXXXLILTLLD-------DKIYWHEALLLVLMYT 227 AGA+ + L+ ++RD + L++ + ++++ + L L+YT Sbjct: 256 --IAGAIEPVSLEPLVLSRDWVAMAVLTLLLMVFGIRKARQGRINRVHGFIFICLYLLYT 313 Query: 228 FYILE 232 Y+L+ Sbjct: 314 LYLLK 318 >UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio fischeri (strain ATCC 700601 / ES114) Length = 323 Score = 56.4 bits (130), Expect = 1e-06 Identities = 27/64 (42%), Positives = 38/64 (59%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 V+ + + + GLTI+A GTSLPE +SV +G M N IGSN F+IL +G+ Sbjct: 201 VIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAGNIIGSNVFNILAVMGI 260 Query: 399 PWLV 402 P L+ Sbjct: 261 PALI 264 Score = 46.4 bits (105), Expect = 0.001 Identities = 27/88 (30%), Positives = 43/88 (48%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 L+L V + + +I + ++ + G T +A +S PEL + G E D+ G Sbjct: 185 LILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAG 244 Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELD 187 ++GS VFN+LAV AL + I D Sbjct: 245 NIIGSNVFNILAVMGIPALINPSEISPD 272 Score = 45.2 bits (102), Expect = 0.003 Identities = 23/56 (41%), Positives = 31/56 (55%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 + G+TILA G+S PE + S G + N IGSN +I L LG+ L+K L Sbjct: 42 VIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNIANIALILGITALIKPL 97 Score = 38.7 bits (86), Expect = 0.29 Identities = 24/115 (20%), Positives = 51/115 (44%), Gaps = 2/115 (1%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + I+ + G T +A SS+PE+ ++ + D VG V+GS + N+ + Sbjct: 32 LARNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNIANIALILGIT 91 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 AL I + R+ + + ++ + ++E LLL+ ++ +I+ Sbjct: 92 ALIKPLAISSA--IIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFII 144 >UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr0681 protein - Synechocystis sp. (strain PCC 6803) Length = 433 Score = 56.4 bits (130), Expect = 1e-06 Identities = 24/58 (41%), Positives = 39/58 (67%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + +L + + + GLT++AAGTSLPE +SV+ + +G + + N +GSN F+IL LG Sbjct: 269 IAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVGNVVGSNIFNILAVLG 326 Score = 54.4 bits (125), Expect = 5e-06 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 FI + + L+LGS V + I + L I+ + G T +AA +S PEL + Sbjct: 242 FIQIAYVVGGVALLVLGS---SLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSV 298 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 V ++ E D+ VG VVGS +FN+LAV A+F+ Sbjct: 299 VASYRGERDIAVGNVVGSNIFNILAVLGFAAIFS 332 Score = 50.4 bits (115), Expect = 9e-05 Identities = 25/56 (44%), Positives = 35/56 (62%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 I GLTI+A GTS+PE V S+ G + I N +GSN F++LL LG+ ++ L Sbjct: 106 IIGLTIVAYGTSMPEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPL 161 Score = 44.8 bits (101), Expect = 0.004 Identities = 18/58 (31%), Positives = 32/58 (55%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 I G T +A +S PE+ ++ + D+ +G VVGS +FNVL + C++ ++ Sbjct: 106 IIGLTIVAYGTSMPEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPLIV 163 >UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; Planctomyces maris DSM 8797|Rep: Sodium/calcium exchanger protein - Planctomyces maris DSM 8797 Length = 368 Score = 56.4 bits (130), Expect = 1e-06 Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Query: 322 CITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGI 381 C+ +GS L+ VV V + + GLTILA GTSLPE SVL +GHG +G Sbjct: 230 CLVVLGS--RLLVTNAVVVARYFEVSELLIGLTILAIGTSLPEYTISVLSIIKGHGALGT 287 Query: 382 SNSIGSNTFDILLCLGLPWLVKSL 405 N IG+N +I + + + L+ L Sbjct: 288 GNIIGANVLNINMVIAICALIHPL 311 Score = 52.8 bits (121), Expect = 2e-05 Identities = 29/93 (31%), Positives = 47/93 (50%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +L+C L + +L + D F + I I I GAT ++ +++ PEL ++ G Sbjct: 23 ILYCSLLILLGMLSITKGGDLFTDSSVEIARLTRIPPVIIGATIVSMSTTFPELMVSVTG 82 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181 T +GDL VG +GS + N+ + CAL G Sbjct: 83 TLAGKGDLAVGNALGSCLCNIGLIIGSCALLKG 115 Score = 43.6 bits (98), Expect = 0.010 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F L F C ++LGS V ++ ++ + G T +A +S PE I+ Sbjct: 219 FKLALMFFCGACLVVLGS---RLLVTNAVVVARYFEVSELLIGLTILAIGTSLPEYTISV 275 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 + G LG G ++G+ V N+ V A CAL Sbjct: 276 LSIIKGHGALGTGNIIGANVLNINMVIAICAL 307 Score = 39.9 bits (89), Expect = 0.13 Identities = 21/58 (36%), Positives = 33/58 (56%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 +P I G TI++ T+ PE + SV T G G + + N++GS +I L +G L+K Sbjct: 57 IPPVIIGATIVSMSTTFPELMVSVTGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLK 114 >UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family protein precursor - Psychromonas ingrahamii (strain 37) Length = 320 Score = 56.4 bits (130), Expect = 1e-06 Identities = 25/66 (37%), Positives = 42/66 (63%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + NVP+++ GLT++A GTSLPE SV+ + H + + N +GSN F++L LG+ Sbjct: 199 IAEHFNVPEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGILGVS 258 Query: 400 WLVKSL 405 ++ L Sbjct: 259 SFLQPL 264 Score = 45.2 bits (102), Expect = 0.003 Identities = 24/55 (43%), Positives = 32/55 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 L V ++GL I+ GTS PE V SV +G + I N +GSN +ILL LG+ Sbjct: 32 LGVSPLLSGLVIVGFGTSAPELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGI 86 Score = 44.8 bits (101), Expect = 0.004 Identities = 19/56 (33%), Positives = 31/56 (55%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I E N+ + G T +A +S PEL I+ + D+ VG ++GS +FN+L + Sbjct: 199 IAEHFNVPEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGI 254 Score = 40.3 bits (90), Expect = 0.095 Identities = 17/67 (25%), Positives = 36/67 (53%) Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 +RL ++ ++G + +S+PEL ++ + D+ +G VVGS + N+L + CA+ Sbjct: 30 KRLGVSPLLSGLVIVGFGTSAPELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAV 89 Query: 179 FAGAVIE 185 ++ Sbjct: 90 ITPLAVK 96 >UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Arabidopsis thaliana|Rep: Na/Ca,K-exchanger-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 559 Score = 56.4 bits (130), Expect = 1e-06 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 7/150 (4%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145 G LL +L L F LLG +YF ++E + + LN++ +AG T ++ + +P+LF + Sbjct: 91 GQFLLFLWLLLL-FYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFAS 149 Query: 146 CVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL-FAGAVIELDWWSVTRDCMMYXX 200 V +F+ E D+G+ VVG + F V ++ + ++ + RD + Sbjct: 150 LV-SFMGESKGTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCA 208 Query: 201 XXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 L L L+ KI + AL +Y Y+ Sbjct: 209 AIGSLALILVYGKINFWGALGFCSLYAVYV 238 Score = 37.5 bits (83), Expect = 0.67 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query: 319 FIMCITWIG-SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV-LVTKQGH 376 F+M +TW S LVA ++T +G V SI GLT+LA G S+ + ++++ + G+ Sbjct: 402 FVMSMTWSYISAQELVA-LLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALHDGN 460 Query: 377 --GTMGISNSIGSNTFDILLCLGL 398 + +S F+ L LG+ Sbjct: 461 EGAQVAVSGCYAGPIFNTLFALGI 484 >UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_11, whole genome shotgun sequence - Paramecium tetraurelia Length = 498 Score = 56.4 bits (130), Expect = 1e-06 Identities = 33/146 (22%), Positives = 69/146 (47%), Gaps = 1/146 (0%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 FIL+ F+ L F + ++ Y PAIE I E+LNI+ ++ T +A A+ + ++ Sbjct: 49 FILMAIFVVLIVFRFMSTLVMFYLTPAIEFITEKLNISQSLSAVTLLAFANGAGDVVTAI 108 Query: 147 VGTFVTEG-DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXL 205 V T + +G++ G+ F V + + + I + + + RD + Y + Sbjct: 109 VATETLDAISYNIGSLYGAGFFVATLVVGITIINSQSYIVMKSYFIWRDILFYIVATIIV 168 Query: 206 ILTLLDDKIYWHEALLLVLMYTFYIL 231 I+ + + ++ L+L+Y ++ Sbjct: 169 IIYGIVGEFSLIDSAFLLLIYIILVI 194 Score = 55.2 bits (127), Expect = 3e-06 Identities = 26/86 (30%), Positives = 50/86 (58%) Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 I+ + WI +S ++ +T G N+ ++ G+TI+A G +LP+ + ++ + KQG+ M Sbjct: 338 IVSLVWIYCLSGILIDTLTFFGMLTNLSNTYLGMTIIAMGNALPDGIVTMTLAKQGYAVM 397 Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL 405 GI+ + F +L+ LG+ L +L Sbjct: 398 GITGAYFGQIFGLLVGLGISLLKTNL 423 >UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome D of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome D of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 638 Score = 56.4 bits (130), Expect = 1e-06 Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 14/174 (8%) Query: 98 CFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE--GD 155 CF+LLG D+ P + + + N + + + +A +SSP+LF N + +E Sbjct: 39 CFVLLGICASDHLCPNVAYLTKSGNTSKGVIASILLAWCNSSPDLFSNLISWLNSESPAT 98 Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT-----LL 210 L +G V+GS + + LF +LD V R+ ++ L +T ++ Sbjct: 99 LSLGEVLGSCGIIICIIQG--LLFYCMKEQLDLTIVQRNSLVTDLLFALLAMTCVLWIVV 156 Query: 211 DDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQN-----GDLERGIEM 259 + + W+ + ++V +Y Y++ K+ D+ Q + N G LE G M Sbjct: 157 ANSVTWYASFIMVAIYVMYVVSKMKLHDSLQGTDDSNKDNIIVGSGRLENGFTM 210 >UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 339 Score = 56.0 bits (129), Expect = 2e-06 Identities = 26/58 (44%), Positives = 38/58 (65%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +++ GLTI+A GTSLPE V+S + +G + I N +GSN +ILL LGL + S+ Sbjct: 226 ETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGLSAAISSV 283 Score = 54.0 bits (124), Expect = 7e-06 Identities = 25/66 (37%), Positives = 37/66 (56%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 V L VP + GLTI+A GTSLPE S + + + N +GSN F++L+ +G+ Sbjct: 31 VAKRLRVPSIVIGLTIVAVGTSLPELAVSTFAAVKHSNAIALGNVVGSNIFNLLMVIGIT 90 Query: 400 WLVKSL 405 L K + Sbjct: 91 ALFKDM 96 Score = 52.8 bits (121), Expect = 2e-05 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +L L L F+LL DYFV + +RL + S + G T +A +S PEL ++ Sbjct: 4 ILDIILLLVGFVLLIKGA-DYFVDGSCAVAKRLRVPSIVIGLTIVAVGTSLPELAVSTFA 62 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 + +G VVGS +FN+L V ALF +++ Sbjct: 63 AVKHSNAIALGNVVGSNIFNLLMVIGITALFKDMLVK 99 Score = 43.6 bits (98), Expect = 0.010 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG- 181 ++ + G T +A +S PEL + V E DL +G VVGS + N+L V A + Sbjct: 224 MSETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGLSAAISSV 283 Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 V +++ + + I+ I E + LV++Y FY+ Sbjct: 284 GVTAMNFVDI---IVSLAATIIVFIVASTQRTIKKKEGIFLVIIYAFYM 329 >UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA family - Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) Length = 305 Score = 56.0 bits (129), Expect = 2e-06 Identities = 25/65 (38%), Positives = 40/65 (61%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + + + +++ GLTI+A GTSLPE +S + + H + + N IGSN F++L LG Sbjct: 186 TQIARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGILG 245 Query: 398 LPWLV 402 + LV Sbjct: 246 ITGLV 250 Score = 45.6 bits (103), Expect = 0.003 Identities = 23/63 (36%), Positives = 35/63 (55%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 V + + + GLTI+ GTS PE + S+ G ++ + N +GSN +ILL LGL Sbjct: 27 VARSYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIANILLILGLT 86 Query: 400 WLV 402 L+ Sbjct: 87 ALI 89 Score = 41.5 bits (93), Expect = 0.041 Identities = 18/56 (32%), Positives = 30/56 (53%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I I+ + G T +A +S PEL + + + ++ VG V+GS +FNVL + Sbjct: 188 IARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGI 243 Score = 37.5 bits (83), Expect = 0.67 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 ++ V + I+ + G T + +S+PEL ++ + VG V+GS + Sbjct: 18 EFLVRGAANVARSYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIA 77 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223 N+L + AL + +D V +D L + LL D + EA +LV Sbjct: 78 NILLILGLTALI--YPVAVDGRRVWKDLAFMVGATVLLWIMLLGDGLSRIEAGVLV 131 >UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya sp. PCC 8106 Length = 315 Score = 56.0 bits (129), Expect = 2e-06 Identities = 33/91 (36%), Positives = 49/91 (53%) Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 I+ L F++ + + S + +G +L I G+TI+A GTSLPE VSS+ Sbjct: 6 IWILVFVVSLIVLIKFSDIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVY 65 Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 QG + SN IGSN +I L +G+ L+ S Sbjct: 66 QGATEIVASNVIGSNVANIFLIIGVATLLSS 96 Score = 51.6 bits (118), Expect = 4e-05 Identities = 23/72 (31%), Positives = 40/72 (55%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 I + D L + + ++ +A GTSLPE + +++G + I N +GSN F+ L+ + Sbjct: 194 IIKIADILGIGKELIAISAVALGTSLPELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVM 253 Query: 397 GLPWLVKSLFYP 408 G+P L + L P Sbjct: 254 GVPGLFEDLIIP 265 Score = 46.8 bits (106), Expect = 0.001 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 13/169 (7%) Query: 65 CTPAAILEFPSDGLTR--FQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122 C E PSDG TR + + +LL C ++ LG+ ++ + +I I + L Sbjct: 150 CGQVETPEMPSDGSTRSSYLFKQIIVLLICTACMF----LGA---NFTIQSIIKIADILG 202 Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 I ++ + +A +S PEL + + + ++ +G V+GS +FN L V LF Sbjct: 203 IGKELIAISAVALGTSLPELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVMGVPGLFEDL 262 Query: 183 VIELDWWSVTRDCM-MYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 +I D + RD + M D K+ E L ++Y ++I Sbjct: 263 IIP-D--IIIRDGLPMLLASTLLFFFVTQDKKVTKWEGWLFFVLYAWFI 308 Score = 41.1 bits (92), Expect = 0.054 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 4/144 (2%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D F I L + I G T +A +S PEL + + ++ V+GS V Sbjct: 23 DIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVYQGATEIVASNVIGSNVA 82 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ + L + + +++ + + D ++ L TL D + EA+L +L Y Sbjct: 83 NIFLIIGVATLLS-SPLKITYNLLDVDLPLFVGSAFLLYFTLSDGDFSFGEAILCILAYL 141 Query: 228 FYILEKINPLDASQRMTPRSVQNG 251 ++ I Q TP +G Sbjct: 142 IHLTYTIR---CGQVETPEMPSDG 162 >UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH0465 protein - Bacillus halodurans Length = 318 Score = 55.6 bits (128), Expect = 2e-06 Identities = 28/62 (45%), Positives = 39/62 (62%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 LNV + GLTI+A GTS PEA +S++ G+ + + N IGSN F+I L +GL L+ Sbjct: 31 LNVSPLLIGLTIVAFGTSSPEATASIIAALNGNPDVALGNVIGSNMFNITLVVGLTALLS 90 Query: 404 SL 405 L Sbjct: 91 PL 92 Score = 47.6 bits (108), Expect = 6e-04 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 4/92 (4%) Query: 97 YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 Y LLLG D+FV I LN++ + G T +A +SSPE + + Sbjct: 3 YVLLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNG 62 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 D+ +G V+GS +FN+ V AL + ++ Sbjct: 63 NPDVALGNVIGSNMFNITLVVGLTALLSPLIV 94 Score = 46.8 bits (106), Expect = 0.001 Identities = 21/60 (35%), Positives = 36/60 (60%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + + + +++ GLTI+A GTSLPE V+S+ + + + N +GS+ F+I LG Sbjct: 198 TAIAFSHGMSETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFNIFFVLG 257 Score = 38.3 bits (85), Expect = 0.38 Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 ++ + G T +A +S PEL + E ++ +G +VGS++FN+ V A Sbjct: 206 MSETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFNIFFVLGTAATI--T 263 Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 + +D V ++ L+ + + +E L+L Y Y++ Sbjct: 264 PMHVDSRVVVDLLLLIFLTLLLLVFSRTRYTVGKYEGLILASFYIGYMV 312 >UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria|Rep: Sodium/calcium exchanger - Shewanella oneidensis Length = 316 Score = 55.6 bits (128), Expect = 2e-06 Identities = 28/57 (49%), Positives = 38/57 (66%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 V + I GLTI+A GTS+PE V+SVL +G + I N +GSN F+IL LG+ +V Sbjct: 198 VSEIIIGLTIVAIGTSMPELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAIV 254 Score = 47.6 bits (108), Expect = 6e-04 Identities = 25/68 (36%), Positives = 37/68 (54%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + L + + GLTI+A GTS PE SV G+ + + N IGSN +I L LG Sbjct: 26 TTIALRLGITPLVIGLTIVAFGTSAPELAVSVKAALAGNSGIALGNVIGSNIVNIGLILG 85 Query: 398 LPWLVKSL 405 + L++ + Sbjct: 86 ITALIRPI 93 Score = 42.3 bits (95), Expect = 0.023 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Query: 93 FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 F+A+ +L+G FV + + ++ I G T +A +S PEL + + Sbjct: 170 FIAVGISMLVGGGI--LFVNGAVDLAKVFGVSEIIIGLTIVAIGTSMPELVTSVLAALKG 227 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCAL 178 + D+ +G +VGS +FN+L + A+ Sbjct: 228 QSDIAIGNIVGSNIFNILGILGVTAI 253 Score = 38.3 bits (85), Expect = 0.38 Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158 FL+L ++ + V I RL I + G T +A +S+PEL ++ + + Sbjct: 11 FLIL-TLGAEALVRGATTIALRLGITPLVIGLTIVAFGTSAPELAVSVKAALAGNSGIAL 69 Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218 G V+GS + N+ + AL IE+ V RD + LLD ++ + Sbjct: 70 GNVIGSNIVNIGLILGITALI--RPIEVKSEMVKRDIPIMILASMLFWGLLLDGELSLID 127 Query: 219 ALLLVLMYTFYIL 231 ++L+ Y++ Sbjct: 128 GVILLSFMLGYLV 140 >UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1; Loktanella vestfoldensis SKA53|Rep: Putative sodium/calcium exchanger - Loktanella vestfoldensis SKA53 Length = 305 Score = 55.6 bits (128), Expect = 2e-06 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 1/86 (1%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 LT + +T + YLV +++ V +++ GL+I+A GTSLPE ++V+ +G Sbjct: 165 LTILGLVTVMVGAHYLVQ-SASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGE 223 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLV 402 + + N +GSN F+IL LG+ +V Sbjct: 224 RDIALGNIVGSNIFNILAILGITAVV 249 Score = 45.2 bits (102), Expect = 0.003 Identities = 20/64 (31%), Positives = 35/64 (54%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 Y V + II + ++ + G + +A +S PEL + E D+ +G +VGS +FN Sbjct: 179 YLVQSASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGERDIALGNIVGSNIFN 238 Query: 169 VLAV 172 +LA+ Sbjct: 239 ILAI 242 Score = 42.3 bits (95), Expect = 0.023 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 2/123 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V + R +A I GA + +S+PEL ++ + + +G V+GS + Sbjct: 19 DWLVKGASGLALRFGVAPIIVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIA 78 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+L V AL V L + V +D + L ++ E L+L+ Sbjct: 79 NILLVLGTAALIGPLV--LTFADVRKDLLWMTGAVLFLPYAFWSGEVSHVEGLVLIGALA 136 Query: 228 FYI 230 Y+ Sbjct: 137 VYL 139 Score = 39.1 bits (87), Expect = 0.22 Identities = 22/56 (39%), Positives = 29/56 (51%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 I G ++ GTS PE + S+ G + I N IGSN +ILL LG L+ L Sbjct: 38 IVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIANILLVLGTAALIGPL 93 >UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter, CaCA family - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 311 Score = 55.6 bits (128), Expect = 2e-06 Identities = 22/63 (34%), Positives = 41/63 (65%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + +P + G++++A GTSLPE +S++ + G++ I N +GSN F++LL LG+ Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGIS 251 Query: 400 WLV 402 L+ Sbjct: 252 LLL 254 Score = 41.5 bits (93), Expect = 0.041 Identities = 21/53 (39%), Positives = 30/53 (56%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + ++ G TI+A GTSLPE V S G+ + + N IGSN ++ L L L Sbjct: 35 ISPALIGSTIIAFGTSLPELVVSTNAAVTGNSGIALGNVIGSNIANVALVLAL 87 Score = 41.1 bits (92), Expect = 0.054 Identities = 20/68 (29%), Positives = 34/68 (50%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + E I + + G + +A +S PEL + V EG + +G ++GS +FN+L V Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGIS 251 Query: 177 ALFAGAVI 184 L A + Sbjct: 252 LLLAPVTV 259 Score = 38.3 bits (85), Expect = 0.38 Identities = 21/77 (27%), Positives = 35/77 (45%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + R I+ + G+T +A +S PEL ++ + +G V+GS + Sbjct: 20 DLFVGGGSGLALRYRISPALIGSTIIAFGTSLPELVVSTNAAVTGNSGIALGNVIGSNIA 79 Query: 168 NVLAVPACCALFAGAVI 184 NV V A C ++ Sbjct: 80 NVALVLALCTFIRPGMV 96 >UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep: Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human) Length = 927 Score = 55.6 bits (128), Expect = 2e-06 Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 +L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G Sbjct: 741 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 798 Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 TS+P+ +S Q + I N GSN ++ L +GL W V ++++ Sbjct: 799 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 847 Score = 39.5 bits (88), Expect = 0.17 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185 Score = 34.7 bits (76), Expect = 4.7 Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398 ++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+ Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184 >UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein; n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium exchanger protein - Tetrahymena thermophila SB210 Length = 5392 Score = 55.2 bits (127), Expect = 3e-06 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 4/187 (2%) Query: 82 QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141 Q I+L ++L F LL S E Y PA+ I + L + +AG T +A + +P+ Sbjct: 4832 QNVPSLIILTIVISLVAFHLLSSTAESYLSPALAKISDSLKCSQTLAGVTLLALGNGAPD 4891 Query: 142 LFINCV--GTFVTEG-DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMY 198 +F + G EG +L +G++ G+ +F V V + ++ D RD Y Sbjct: 4892 VFTAIIAGGGNDDEGINLAIGSIFGAGLF-VTTVTLAKVIKNSDELKADKNIFIRDVGFY 4950 Query: 199 XXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIE 258 +++ LL K+ + A+ +Y +I+ I ++R + + E Sbjct: 4951 CFAAFLILIYLLIGKVNFPMAVAFFSLYFVFIIVVIYQEWDAKRKRKNGINAQLISDENE 5010 Query: 259 MTRRHDS 265 + RH S Sbjct: 5011 LQNRHMS 5017 Score = 36.3 bits (80), Expect = 1.5 Identities = 18/60 (30%), Positives = 31/60 (51%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 NV + GLT LA G S + ++ + K G+G M ++ F+ LL G+ ++K+ Sbjct: 5284 NVNKAYLGLTFLAFGNSAGDFFTNPQLAKMGYGIMAMTGCFAGQLFNTLLGFGIALILKT 5343 >UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; Pirellula sp.|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 339 Score = 55.2 bits (127), Expect = 3e-06 Identities = 26/55 (47%), Positives = 38/55 (69%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 L V + + GLTI++AGTSLPE V+SV T +G + I N++GS T +I+ LG+ Sbjct: 218 LGVSELVIGLTIVSAGTSLPELVTSVAATIKGERGIAIGNAVGSTTLNIVAVLGI 272 Score = 44.4 bits (100), Expect = 0.006 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + L ++ + G T ++A +S PEL + T E + +G VGS Sbjct: 205 DLFVDGAVSMARILGVSELVIGLTIVSAGTSLPELVTSVAATIKGERGIAIGNAVGSTTL 264 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDC-MMYXXXXXXLILTLLDDKIYWHEALLLVLMY 226 N++AV ++ A + + + + D +M IL I E +L++++Y Sbjct: 265 NIVAVLGITSVIAPSGLNVADEILRLDMPLMVIAAMLSWILYRTGRTIVRWEGVLMIVIY 324 Query: 227 TFYI 230 Y+ Sbjct: 325 CSYV 328 Score = 42.3 bits (95), Expect = 0.023 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 316 PLTFIMCITWIGSVSYLVA---WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369 P+ I+ + +G V L+ W++ + + + GLT+++ GTS PE S Sbjct: 6 PMNGIIALQILGGVLLLLIGGEWVVRGASRLAIAAKLSPLFVGLTVVSLGTSAPEMAVSF 65 Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +G + I N +GSN F++L+ +G L L Sbjct: 66 ATALRGQADITIGNVVGSNLFNMLMIVGFSALFAPL 101 Score = 41.9 bits (94), Expect = 0.031 Identities = 30/115 (26%), Positives = 59/115 (51%), Gaps = 8/115 (6%) Query: 120 RLNIASDIA----GATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 RL IA+ ++ G T ++ +S+PE+ ++ + D+ +G VVGS +FN+L + Sbjct: 35 RLAIAAKLSPLFVGLTVVSLGTSAPEMAVSFATALRGQADITIGNVVGSNLFNMLMIVGF 94 Query: 176 CALFAGAVIELDWWSVTR-DCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 ALFA ++ +TR D + +++ L+ I + ++L+L+ Y Sbjct: 95 SALFAPLPVDR---QITRFDVPVMIAATIAMLVASLNGIIGRFDGIVLILIMIGY 146 >UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family - Parvibaculum lavamentivorans DS-1 Length = 334 Score = 55.2 bits (127), Expect = 3e-06 Identities = 27/64 (42%), Positives = 40/64 (62%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 V DS+ GLT++A GTSLPE +SVL + + I N +GSN F++L G+ +VK + Sbjct: 223 VSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPV 282 Query: 406 FYPS 409 P+ Sbjct: 283 PVPA 286 Score = 50.4 bits (115), Expect = 9e-05 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%) Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368 R + Y + + +G +LV ++ L V + GLT++ GTS PE V+S Sbjct: 14 REQELTYLFLVVGLVLLLGGAEFLVKGAASLA-TRLGVSPFLIGLTLVGFGTSAPELVAS 72 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 + QG+ + + N +GSN +ILL LG+ L+ Sbjct: 73 LEGAFQGYPGIAVGNVVGSNIANILLILGIAGLI 106 Score = 48.0 bits (109), Expect = 5e-04 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 2/118 (1%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 A+EI R ++ + G T +A +S PE+ + + F + D+ +G VVGS +FNVL + Sbjct: 214 AVEI-ATRHGVSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGI 272 Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 A+ + D +M L+ +I EALLL+ Y Y+ Sbjct: 273 AGMVAVVKPVPVPADIAGFD-IWVMGAASLLFLVFAWTGSRIGRVEALLLLGGYGAYV 329 Score = 46.0 bits (104), Expect = 0.002 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 80 RFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSS 139 RF+ Q L + FL + LLLG ++ V + RL ++ + G T + +S+ Sbjct: 12 RFREQE---LTYLFLVVGLVLLLGGA--EFLVKGAASLATRLGVSPFLIGLTLVGFGTSA 66 Query: 140 PELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 PEL + G F + VG VVGS + N+L + Sbjct: 67 PELVASLEGAFQGYPGIAVGNVVGSNIANILLI 99 >UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; Moritella sp. PE36|Rep: Putative uncharacterized protein - Moritella sp. PE36 Length = 340 Score = 55.2 bits (127), Expect = 3e-06 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 3/142 (2%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 +LL L F+LL +V D + + ++ ++ G T +A +S PEL ++ + Sbjct: 3 LLLPIIAVLVGFILL-TVSADRLILVSSTLAKQFGVSVMFIGMTVIAFGTSFPELVVSAI 61 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207 +F L VG +GS + N V A CALF VI++ + + R+ + I Sbjct: 62 ASFNGAEGLAVGNAIGSNIINCGLVLALCALFMPLVIKVRF--IKRELPILVFALIATIA 119 Query: 208 TLLDDKIYWHEALLLVLMYTFY 229 + + I ++L+L+L+ Y Sbjct: 120 LMSNGSITMWDSLILILLLALY 141 Score = 54.4 bits (125), Expect = 5e-06 Identities = 26/73 (35%), Positives = 42/73 (57%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S ++ W + + V D + GLTI+A GTSLPE +++ ++G + + IGSNT Sbjct: 183 SQIMVWGSVQLAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNT 242 Query: 390 FDILLCLGLPWLV 402 F++L L P L+ Sbjct: 243 FNLLGVLAFPGLI 255 Score = 40.3 bits (90), Expect = 0.095 Identities = 19/47 (40%), Positives = 28/47 (59%) Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 G+T++A GTS PE V S + + G + + N+IGSN + L L L Sbjct: 43 GMTVIAFGTSFPELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLAL 89 Score = 34.7 bits (76), Expect = 4.7 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + + + ++ + G T +A +S PEL G ++ V+GS FN+L V A Sbjct: 193 LAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNTFNLLGVLAFP 252 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208 L G ++L +TRD M ++++ Sbjct: 253 GLI-GDGLQLPAEVLTRDLPMLSIMTAFMVIS 283 >UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomonadaceae|Rep: Sodium/calcium exchanger - Oceanicaulis alexandrii HTCC2633 Length = 334 Score = 55.2 bits (127), Expect = 3e-06 Identities = 29/73 (39%), Positives = 40/73 (54%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + VP + GLTI+A GTS PE V S +G + I N +GSN ++LL LG Sbjct: 30 TALASKAGVPPLLVGLTIVAFGTSAPEMVVSAAAAVEGAPGLAIGNIVGSNIANVLLVLG 89 Query: 398 LPWLVKSLFYPST 410 LP L+ + +T Sbjct: 90 LPALLAPIASTAT 102 Score = 55.2 bits (127), Expect = 3e-06 Identities = 27/60 (45%), Positives = 37/60 (61%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 NVPD++ GLTILA GTSLPE ++++ + M I N +GSN F+I G+ L S Sbjct: 208 NVPDAVIGLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAAS 267 Score = 42.3 bits (95), Expect = 0.023 Identities = 22/64 (34%), Positives = 31/64 (48%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I N+ + G T +A +S PEL V + D+ +G VVGS +FN+ AV Sbjct: 203 IAALFNVPDAVIGLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGIT 262 Query: 177 ALFA 180 L A Sbjct: 263 GLAA 266 Score = 37.5 bits (83), Expect = 0.67 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 94 LALYCFLLLGSVCE-----DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 + L+ ++LG + D V + + + + G T +A +S+PE+ ++ Sbjct: 4 ILLFSLMVLGGIVVLLTGGDILVRGATALASKAGVPPLLVGLTIVAFGTSAPEMVVSAAA 63 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L +G +VGS + NVL V AL A Sbjct: 64 AVEGAPGLAIGNIVGSNIANVLLVLGLPALLA 95 >UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Enterobacteriaceae|Rep: Inner membrane protein yrbG - Escherichia coli (strain K12) Length = 325 Score = 55.2 bits (127), Expect = 3e-06 Identities = 24/65 (36%), Positives = 41/65 (63%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 TV+ + + + GLT +A GTSLPE +++ ++G + + N IG+N F+I++ LG Sbjct: 198 TVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLG 257 Query: 398 LPWLV 402 LP L+ Sbjct: 258 LPALI 262 Score = 51.2 bits (117), Expect = 5e-05 Identities = 23/61 (37%), Positives = 37/61 (60%) Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 T +P I G+T+++ GTSLPE + S+ + + + ++GSN +ILL LGL LV Sbjct: 32 TFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALV 91 Query: 403 K 403 + Sbjct: 92 R 92 Score = 46.0 bits (104), Expect = 0.002 Identities = 26/88 (29%), Positives = 40/88 (45%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 LLL D V A I+C I I G T ++ +S PE+ ++ + + DL VG Sbjct: 12 LLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVG 71 Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELD 187 +GS + N+L + AL + D Sbjct: 72 TALGSNIINILLILGLAALVRPFTVHSD 99 Score = 42.7 bits (96), Expect = 0.018 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 4/140 (2%) Query: 55 LLGIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAI 114 LL IV++ R + L R G + FL L L++ V V Sbjct: 140 LLFIVKLARQAERQGTDSLTREQLAELPRDGGLPV--AFLWLGIALIIMPVATRMVVDNA 197 Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174 ++ I+ G T +A +S PEL G E D+ VG ++G+ +FN++ V Sbjct: 198 TVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLG 257 Query: 175 CCALFAGAVIELDWWSVTRD 194 AL E+D + +RD Sbjct: 258 LPALITPG--EIDPLAYSRD 275 >UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1; Takifugu rubripes|Rep: Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu rubripes Length = 953 Score = 54.8 bits (126), Expect = 4e-06 Identities = 30/109 (27%), Positives = 58/109 (53%), Gaps = 3/109 (2%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 IL+A IP + + FI+ + IG ++ ++ + + G T+ + D++T + +A G Sbjct: 767 ILFACIPPTEYWNGW--ACFIVSVVGIGFLTAIIGDVASHFGCTVGLRDTVTAVVFVALG 824 Query: 360 TSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 TSLP+ S T+ + + N GSN ++ L +GL W V ++++ Sbjct: 825 TSLPDTFASKFAATQDQYADACVGNVTGSNAVNVFLGIGLAWSVAAVYW 873 Score = 44.4 bits (100), Expect = 0.006 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 10/115 (8%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA--- 180 ++ T MA SS+PE+ ++ + G G+LG G +VGSA FN+ + C L Sbjct: 80 VSNLTLMALGSSAPEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLCVLIIPEG 139 Query: 181 --GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYIL 231 + L + VT ++ LIL ++ I W + LV F IL Sbjct: 140 EHRRIKHLRVYFVTAFWSVFAYIWLYLILAVISPGIVEVWEAVVTLVYFPLFVIL 194 Score = 34.3 bits (75), Expect = 6.2 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 348 DSITGLTILAAGTSLPEAVSSVL-VTKQGH--GTMGISNSIGSNTFDILLCLGLPWLV 402 ++++ LT++A G+S PE + SV+ V G G +G +GS F++ + +GL L+ Sbjct: 78 ETVSNLTLMALGSSAPEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLCVLI 135 >UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF10698, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 793 Score = 54.8 bits (126), Expect = 4e-06 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 1/95 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 F++ I+ IG ++ ++ I + G T+ + DS+T + +A GTS+P+ S V + + Sbjct: 624 FMVSISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 683 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPE 412 I N GSN ++ L +G+ W + ++++ S E Sbjct: 684 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGE 718 Score = 41.1 bits (92), Expect = 0.054 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Query: 112 PAIEIICERLNIASD-IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVF 167 P E I R+ + ++ ++ T MA SS+PE+ ++ V G G+LG +VGSA F Sbjct: 54 PGGEKISTRVRVWNETVSNLTLMALGSSAPEILLSVVEVCGHNFNAGELGPNTIVGSAAF 113 Query: 168 NVLAVPACC 176 N+ + C Sbjct: 114 NMFVIIGLC 122 Score = 34.3 bits (75), Expect = 6.2 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 5/55 (9%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398 ++++ LT++A G+S PE + SV V GH G +G + +GS F++ + +GL Sbjct: 68 ETVSNLTLMALGSSAPEILLSV-VEVCGHNFNAGELGPNTIVGSAAFNMFVIIGL 121 >UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 313 Score = 54.8 bits (126), Expect = 4e-06 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + L ++ + G T +AA +S PEL + V + + D+ +G +VGS +FN+L + C Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC 253 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 +L IE + +M L L KI E +L+L Y Y+ Sbjct: 254 SLI--HPIEAKNVNYIDLLVMLGISVLLLPLVKSGQKISRTEGFVLILFYVIYM 305 Score = 50.8 bits (116), Expect = 7e-05 Identities = 23/58 (39%), Positives = 36/58 (62%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + L V +++ GLTI+AAGTS+PE +S++ + + I N +GSN F+IL G Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAG 251 Score = 49.6 bits (113), Expect = 2e-04 Identities = 24/49 (48%), Positives = 32/49 (65%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + GLTI+A GTS PE V S+ T G G + I N +GSN F+I + LG+ Sbjct: 39 VVGLTIVAFGTSAPELVVSLNATLSGQGDIAIGNIVGSNIFNIGVILGV 87 Score = 42.7 bits (96), Expect = 0.018 Identities = 18/61 (29%), Positives = 34/61 (55%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 + V + + I+ + G T +A +S+PEL ++ T +GD+ +G +VGS +FN Sbjct: 21 WLVQGSSALALKAKISPLVVGLTIVAFGTSAPELVVSLNATLSGQGDIAIGNIVGSNIFN 80 Query: 169 V 169 + Sbjct: 81 I 81 >UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Parvularcula bermudensis HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Parvularcula bermudensis HTCC2503 Length = 327 Score = 54.8 bits (126), Expect = 4e-06 Identities = 25/66 (37%), Positives = 38/66 (57%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + L +P + GLTI+A GTS PE V S+ G + + N +GSN ++ L LGLP Sbjct: 29 IATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGSNIANVFLVLGLP 88 Query: 400 WLVKSL 405 L+ ++ Sbjct: 89 ALISAI 94 Score = 48.0 bits (109), Expect = 5e-04 Identities = 21/54 (38%), Positives = 33/54 (61%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 L V + + GLT++A GTSLPE + + ++ ++ + N IGSN F+IL G Sbjct: 204 LGVREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFNILFVGG 257 Score = 42.3 bits (95), Expect = 0.023 Identities = 25/76 (32%), Positives = 37/76 (48%) Query: 105 VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGS 164 V D+ V I RL I S + G T +A +S+PEL ++ + + VG +VGS Sbjct: 17 VAGDFLVRGAVGIATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGS 76 Query: 165 AVFNVLAVPACCALFA 180 + NV V AL + Sbjct: 77 NIANVFLVLGLPALIS 92 Score = 41.1 bits (92), Expect = 0.054 Identities = 29/111 (26%), Positives = 43/111 (38%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L + ++ G T +A +S PEL E + VG V+GS +FN+L V +F Sbjct: 204 LGVREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFNILFVGGAMGVFG 263 Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 V + M I L I +L +L Y YI+ Sbjct: 264 TTVFSDPGTKIYDVPAMVVAALALAIPLYLRMTITRTVGILFILAYIAYIV 314 >UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2; Caenorhabditis|Rep: Na/ca exchangers protein 10 - Caenorhabditis elegans Length = 668 Score = 54.8 bits (126), Expect = 4e-06 Identities = 25/83 (30%), Positives = 46/83 (55%), Gaps = 3/83 (3%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 I++ L+ F+++ V +D+F P+I I L I+ IAG TF+A + +P++F + Sbjct: 104 IIISIIYLLFLFVVMTVVADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIA 163 Query: 148 GTFVT---EGDLGVGAVVGSAVF 167 T + DL +G ++G +F Sbjct: 164 SVITTPKPKADLAIGDIIGGGIF 186 Score = 54.0 bits (124), Expect = 7e-06 Identities = 29/77 (37%), Positives = 42/77 (54%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F+M I WI ++S + +IT++G V I GLTI+A + + VS V V KQG Sbjct: 495 LGFLMSIAWIYTISSEIINVITMIGVATGVSQEILGLTIMAWSNCIGDIVSDVAVVKQGF 554 Query: 377 GTMGISNSIGSNTFDIL 393 M ++ +IG F L Sbjct: 555 PKMAMAAAIGGPLFSKL 571 >UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|Rep: Cation exchanger - Cryptosporidium hominis Length = 940 Score = 54.8 bits (126), Expect = 4e-06 Identities = 29/86 (33%), Positives = 48/86 (55%) Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 IM I W G + + I V+G TL + +I GLTI+A G S+ + ++V V++ GH M Sbjct: 790 IMSIYWNGVLVNELVECIKVIGLTLGIKPAILGLTIVAMGNSIADLFANVAVSRAGHAHM 849 Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL 405 G++ G+ F +L G V+++ Sbjct: 850 GLAGCYGACVFLLLFGFGSSVFVRAI 875 Score = 43.6 bits (98), Expect = 0.010 Identities = 23/94 (24%), Positives = 50/94 (53%), Gaps = 5/94 (5%) Query: 92 CFLALYCFLLL--GSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149 C L C L + G+V + Y + + E L+++ AG+T +A ++++ ++ + + Sbjct: 104 CLLVWSCILFIACGTVADTYISSLMIKLAECLSLSDTFAGSTLLAFSNAASDVILGIISV 163 Query: 150 FVTEG---DLGVGAVVGSAVFNVLAVPACCALFA 180 + E D+ +G V+G+ +F +L V C +F+ Sbjct: 164 SIGEKDAVDVFLGDVIGACLFIILVVFGCVMVFS 197 >UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+ antiporter, CaCA family - Parvibaculum lavamentivorans DS-1 Length = 350 Score = 54.4 bits (125), Expect = 5e-06 Identities = 26/68 (38%), Positives = 40/68 (58%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + V D++ GL+++A GTSLPE +SV+ + + M + N IGSN +IL LG Sbjct: 223 TEIAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILG 282 Query: 398 LPWLVKSL 405 + L+ L Sbjct: 283 VTALIAPL 290 Score = 45.2 bits (102), Expect = 0.003 Identities = 24/65 (36%), Positives = 34/65 (52%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + V + LTI+A GTS PE + S+ G + + N +GSN +I L LG Sbjct: 27 TALAARYGVSPLLIALTIVAFGTSAPELLVSIRAALAGSPGIALGNVVGSNIANIFLILG 86 Query: 398 LPWLV 402 LP L+ Sbjct: 87 LPALI 91 Score = 44.8 bits (101), Expect = 0.004 Identities = 21/72 (29%), Positives = 38/72 (52%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + ++ + G + +A +S PEL + + F D+ VG ++GS + N+LA+ Sbjct: 225 IAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILGVT 284 Query: 177 ALFAGAVIELDW 188 AL A I+ D+ Sbjct: 285 ALIAPLPIDPDF 296 Score = 41.9 bits (94), Expect = 0.031 Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 6/142 (4%) Query: 94 LALYCFLLLGSV----CEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149 + +Y +L+ G V C D+ V + R ++ + T +A +S+PEL ++ Sbjct: 2 IEMYAYLIGGLVILLVCGDFLVRGATALAARYGVSPLLIALTIVAFGTSAPELLVSIRAA 61 Query: 150 FVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTL 209 + +G VVGS + N+ + AL I +V + ++ LI+ Sbjct: 62 LAGSPGIALGNVVGSNIANIFLILGLPALI--YPIACTGRTVPHNMIVMMAASVLLIVLC 119 Query: 210 LDDKIYWHEALLLVLMYTFYIL 231 + + + +LL+ + T Y++ Sbjct: 120 FVGTLSFWQGVLLISLLTAYLV 141 >UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein; n=1; Plesiocystis pacifica SIR-1|Rep: K+-dependent Na+/Ca+ exchanger protein - Plesiocystis pacifica SIR-1 Length = 325 Score = 54.4 bits (125), Expect = 5e-06 Identities = 25/59 (42%), Positives = 38/59 (64%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L + GLTI+AAGTSLPE V+SV+ + +G + ++N +GSN F++ LG L+ Sbjct: 209 LGASQRVVGLTIVAAGTSLPELVTSVIASVRGRDDIALTNVLGSNIFNVFGILGTTTLI 267 Score = 52.8 bits (121), Expect = 2e-05 Identities = 28/68 (41%), Positives = 39/68 (57%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + L V ++ GLTI+AAGTS+PE V S G + ++N IGSN F+I +G Sbjct: 27 TSLAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIALANVIGSNIFNIAAIVG 86 Query: 398 LPWLVKSL 405 + LV L Sbjct: 87 VAALVAPL 94 Score = 46.8 bits (106), Expect = 0.001 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + + L ++ + G T +AA +S PEL ++ E D+ + V+GS +FN+ A+ Sbjct: 29 LAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIALANVIGSNIFNIAAIVGVA 88 Query: 177 ALFA-----GAVIELDW 188 AL A G + L+W Sbjct: 89 ALVAPLRVLGNSVRLEW 105 Score = 39.9 bits (89), Expect = 0.13 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Query: 68 AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127 A L P G R + F L L + +L GSV V + L + + Sbjct: 160 AEALPAPLGGELRGAKAWLFSGLGLVLGMALLVLGGSV----LVNGASALALGLGASQRV 215 Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187 G T +AA +S PEL + + + D+ + V+GS +FNV + L A ++ + Sbjct: 216 VGLTIVAAGTSLPELVTSVIASVRGRDDIALTNVLGSNIFNVFGILGTTTLIAPVAVDPE 275 Query: 188 WWSV 191 SV Sbjct: 276 LVSV 279 >UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Pseudomonas stutzeri (strain A1501) Length = 361 Score = 54.0 bits (124), Expect = 7e-06 Identities = 28/60 (46%), Positives = 36/60 (60%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +P I GLT++A GTS PE SV + G G + + N IGSN +ILL LGL L+ L Sbjct: 36 IPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIAPL 95 Score = 50.0 bits (114), Expect = 1e-04 Identities = 22/54 (40%), Positives = 35/54 (64%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 L + + + GLT++A GTS+PE +SVL +G + + N +GS F++LL LG Sbjct: 207 LGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLVLG 260 Score = 42.7 bits (96), Expect = 0.018 Identities = 22/68 (32%), Positives = 35/68 (51%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + R I I G T +A +S+PE ++ + GD+ VG V+GS + N+L + Sbjct: 30 LASRFGIPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLS 89 Query: 177 ALFAGAVI 184 AL A V+ Sbjct: 90 ALIAPLVV 97 Score = 42.7 bits (96), Expect = 0.018 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 3/112 (2%) Query: 62 ERNCTPAAILEFPSD-GLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICER 120 +R PA EF ++ G + ++ + L LL+G + + + Sbjct: 149 KREKAPAGDDEFATEFGPDESDKPFAWVFQLLLILLGLGLLVGG--SNLLIEGAVGLARA 206 Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 L ++ + G T +A +S PEL + + E D+ VG VVGS +FN+L V Sbjct: 207 LGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLV 258 >UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os11g0148000 protein - Oryza sativa subsp. japonica (Rice) Length = 293 Score = 54.0 bits (124), Expect = 7e-06 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 3/139 (2%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L F +L + +F PA+ + RL ++ +A T +A + +P+ F + Sbjct: 73 LLLLHFRVLAAAAGTHFSPAVSRLAARLRLSPSMAAVTLLALGNGAPDAFASAAALGGAG 132 Query: 154 G--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD 211 G G+ A++ + F V AL A A + S RD Y L L Sbjct: 133 GMRRAGLAAILSAGAFVSAFVVGAVALIA-APFAVPPASFARDVFFYLLAASGLFYIYLS 191 Query: 212 DKIYWHEALLLVLMYTFYI 230 +IY +A+ LVL Y F++ Sbjct: 192 AEIYLWQAIGLVLFYVFFV 210 >UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2; Pichia stipitis|Rep: Sodium/calcium exchanger protein - Pichia stipitis (Yeast) Length = 686 Score = 54.0 bits (124), Expect = 7e-06 Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 2/132 (1%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158 F+ LG DY P + I + L ++ +++G T +A + SP++ G L + Sbjct: 62 FISLGLTASDYLCPNLYTISKFLKLSDNLSGLTLLALGNGSPDVLSTFKAMSFGSGSLAI 121 Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218 ++G+++F V C A+ +++ RD + Y LI TL+ + Sbjct: 122 SELMGASLFVTTVVIGCIAIV--HPLKVPRRLFVRDTIFYLMIACLLIFTLVRQSLTLPI 179 Query: 219 ALLLVLMYTFYI 230 +++LV Y Y+ Sbjct: 180 SIILVSSYVLYV 191 Score = 43.2 bits (97), Expect = 0.013 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FI+ +TWI + + I+ + ++ D I G+T+ A G S+ + +S+ + K G Sbjct: 534 FIVSVTWIAIFATEIIAILKSISIIYSLSDDILGVTVFALGNSIGDLISNFTIAKMGMPA 593 Query: 379 MGISNSIGSNTFDILLCLGLPWLV 402 M + +G L LG+ L+ Sbjct: 594 MALGACLGGPLLS-LCSLGMSGLI 616 Score = 40.7 bits (91), Expect = 0.072 Identities = 20/65 (30%), Positives = 36/65 (55%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + D+++GLT+LA G P+ +S+ G G++ IS +G++ F + +G +V Sbjct: 84 LKLSDNLSGLTLLALGNGSPDVLSTFKAMSFGSGSLAISELMGASLFVTTVVIGCIAIVH 143 Query: 404 SLFYP 408 L P Sbjct: 144 PLKVP 148 >UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein; n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium exchanger protein - Tetrahymena thermophila SB210 Length = 602 Score = 53.6 bits (123), Expect = 9e-06 Identities = 36/179 (20%), Positives = 81/179 (45%), Gaps = 5/179 (2%) Query: 57 GIVE-IERNCTPAAILEFPSDGLTRFQRQHGFI-LLHCFLALYCFLLLGSVCEDYFVPAI 114 G+ E +++NCT +++ F + + LL + L F +L S E Y PA+ Sbjct: 20 GVCEYVDQNCTAESLVRFSYFYFCQVSENIIVLDLLTVLVPLMAFHMLSSTAESYLSPAL 79 Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG--DLGVGAVVGSAVFNVLAV 172 + L ++ +AG T +A + +P++ + G + +G++ G+ +F V Sbjct: 80 AKCSKILRLSESVAGVTLLALGNGAPDVITAIIAGGDDNGGISIAIGSIFGAGLF-VTTA 138 Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 +F G I++D + RD + Y +++ + K+ + + + +Y +++ Sbjct: 139 TLSAVIFHGKNIKIDKKTFMRDMVFYLLGCLVILVYAIIGKVNIIMSSIFMSIYLIFLV 197 Score = 38.3 bits (85), Expect = 0.38 Identities = 17/88 (19%), Positives = 44/88 (50%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F++ + +I +++ ++ I + + GLT+LA G S + ++ ++K G+ Sbjct: 435 LAFVISVAYISTIAQILIDFIQFFQILSGINQTFLGLTLLAYGNSSGDFFTNTQLSKMGY 494 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKS 404 G M ++ F++ + G ++++ Sbjct: 495 GVMAMTGCFAGQGFNLYIGFGFALVMQT 522 >UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=8; Bacteroidales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 317 Score = 53.6 bits (123), Expect = 9e-06 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Query: 311 RHSIYPLTFIMCITWIGSVSY---LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367 R PL+ IM I + ++ + L ++ + V +S+ +TI+A GTSLPE V+ Sbjct: 165 RQFALPLSIIMVIGGLVALVFGGDLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPELVT 224 Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 +++ + M I N +GSN F+ILL LG+ Sbjct: 225 TLVAAIKKRPGMAIGNIVGSNLFNILLILGV 255 Score = 52.4 bits (120), Expect = 2e-05 Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385 +G ++L ++ + D + GLT+LA GTS PE S++ +G + I N I Sbjct: 16 VGGANFLTDGAASIA-KRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVI 74 Query: 386 GSNTFDILLCLGLPWLVKSL 405 GSN F+IL +G+ L+ L Sbjct: 75 GSNIFNILAIVGITALIMPL 94 Score = 47.2 bits (107), Expect = 8e-04 Identities = 20/62 (32%), Positives = 36/62 (58%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I +R ++ + G T +A +S+PEL ++ + D+ +G V+GS +FN+LA+ Sbjct: 29 IAKRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVIGSNIFNILAIVGIT 88 Query: 177 AL 178 AL Sbjct: 89 AL 90 Score = 41.9 bits (94), Expect = 0.031 Identities = 18/65 (27%), Positives = 32/65 (49%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV ++ R+ ++ + T +A +S PEL V + +G +VGS +F Sbjct: 188 DLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPELVTTLVAAIKKRPGMAIGNIVGSNLF 247 Query: 168 NVLAV 172 N+L + Sbjct: 248 NILLI 252 >UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; n=7; Caenorhabditis|Rep: Na/ca exchangers protein 2, isoform a - Caenorhabditis elegans Length = 975 Score = 53.6 bits (123), Expect = 9e-06 Identities = 32/117 (27%), Positives = 64/117 (54%), Gaps = 4/117 (3%) Query: 292 VLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSIT 351 VLT P +L +ATIP + TF++ I IG ++ +V + + G + + D++T Sbjct: 782 VLTVPWKLT-FATIPPTDYFGGW--ATFVVAIFMIGVLTAVVGDLASQFGCWVGLKDAVT 838 Query: 352 GLTILAAGTSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407 ++ +A GTS+P+ +S V + + + N GSN ++ L +G+ W + ++++ Sbjct: 839 AISFVALGTSVPDTFASKVSAVQDKYADNAVGNVTGSNAVNVFLGIGIAWSMAAIYH 895 Score = 43.2 bits (97), Expect = 0.013 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Query: 112 PAIEIICERLNIASD-IAGATFMAAASSSPELFINCVGTFVT---EGDLGVGAVVGSAVF 167 P ++ + ++ I +D ++ T MA SS+PE+ ++ + GDLG +VGSA F Sbjct: 99 PGLDPMAVQVRIWNDTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAF 158 Query: 168 NVLAVPACCAL 178 N+ + A C + Sbjct: 159 NLFMIIAICVV 169 Score = 33.9 bits (74), Expect = 8.2 Identities = 16/54 (29%), Positives = 34/54 (62%), Gaps = 3/54 (5%) Query: 348 DSITGLTILAAGTSLPEAVSSVL-VTKQGH--GTMGISNSIGSNTFDILLCLGL 398 D+++ LT++A G+S PE + S++ V +G G +G + +GS F++ + + + Sbjct: 113 DTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAI 166 >UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; Methanosarcina|Rep: Sodium/calcium exchanger protein - Methanosarcina acetivorans Length = 418 Score = 53.6 bits (123), Expect = 9e-06 Identities = 23/62 (37%), Positives = 40/62 (64%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L +P+++ G++++A GTSLPE + ++ + G+ ++ + N IGSN + LL LG LV Sbjct: 303 LEIPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIGSNITNTLLILGCSGLVN 362 Query: 404 SL 405 L Sbjct: 363 PL 364 Score = 51.2 bits (117), Expect = 5e-05 Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D FV + I ER ++ I G T ++ +S PEL + + +G V+GS + Sbjct: 21 DLFVMSSSWIAERFGVSEFIIGLTLVSIGTSVPELASALTASLEHASGIVIGDVLGSNIA 80 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ + + AL + + + + RD + +L++LD +I EAL+ +L Y Sbjct: 81 NIGLIVSTAALLSN--VRTEELMLRRDGYIMLFSLFIFLLSILDFRISRLEALIFLLFYF 138 Query: 228 FYIL 231 Y+L Sbjct: 139 VYLL 142 Score = 35.5 bits (78), Expect = 2.7 Identities = 18/66 (27%), Positives = 37/66 (56%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + V + I GLT+++ GTS+PE S++ + + + I + +GSN +I L + Sbjct: 30 IAERFGVSEFIIGLTLVSIGTSVPELASALTASLEHASGIVIGDVLGSNIANIGLIVSTA 89 Query: 400 WLVKSL 405 L+ ++ Sbjct: 90 ALLSNV 95 Score = 34.7 bits (76), Expect = 4.7 Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 3/119 (2%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168 YF+ L I + G + +A +S PEL + + +G V+GS + N Sbjct: 291 YFIEQSIFFALLLEIPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIGSNITN 350 Query: 169 VLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMY 226 L + C L V ++ + +T M L+ +I E ++L+L+Y Sbjct: 351 TLLILGCSGLVNPLTVTKISIYYITP--FMLFISLLLLLFIRTGWRIKRTEGVILLLLY 407 >UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependent Na/Ca exchanger NCKX4, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to K-dependent Na/Ca exchanger NCKX4, partial - Strongylocentrotus purpuratus Length = 76 Score = 53.2 bits (122), Expect = 1e-05 Identities = 24/58 (41%), Positives = 36/58 (62%) Query: 62 ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICE 119 E NCT I +FP T QR+ G ++++ ++LY +G VC YFVP++EI+CE Sbjct: 19 EDNCTVRGISKFPRGVFTNEQRKGGALVVNFLVSLYLCGAIGYVCAAYFVPSLEILCE 76 >UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Clostridium oremlandii OhILAs|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Clostridium oremlandii OhILAs Length = 310 Score = 53.2 bits (122), Expect = 1e-05 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 6/116 (5%) Query: 309 RHRHSIYPLTFIMCITWIGSV--SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366 R + + F + + IG V Y + + L + GLT++A GTSLPE + Sbjct: 159 RQSMDLIHILFYLVLGIIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSLPELI 218 Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFI 422 + ++ + + + + N IGSN F+IL L V SL P +H + DL F+ Sbjct: 219 TCLVACHKKNDDIAVGNIIGSNIFNILFVLS----VSSLISPIAFSSHLIIDLAFM 270 Score = 46.8 bits (106), Expect = 0.001 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 3/132 (2%) Query: 101 LLGSVCEDYFVPAIEI-ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 ++G V Y++ + I L + G T +A +S PEL V D+ VG Sbjct: 175 IIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSLPELITCLVACHKKNDDIAVG 234 Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEA 219 ++GS +FN+L V + +L + I + M I + KI E Sbjct: 235 NIIGSNIFNILFVLSVSSLI--SPIAFSSHLIIDLAFMLLFTFLLFIFSYTHKKISRLEG 292 Query: 220 LLLVLMYTFYIL 231 +L+++Y FY + Sbjct: 293 FVLMMLYLFYFV 304 Score = 43.2 bits (97), Expect = 0.013 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 3/92 (3%) Query: 317 LTFIMCITWIGSVSYLVAWII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 + FI+ I ++ W+I + + L + I GLT++A GTS PEA +++ + Sbjct: 4 IPFIVLIVSFLAIIKSADWLIDASSALALYLGISPLIVGLTVVAFGTSAPEASVNIIASF 63 Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 Q + I N GSN +I + +G+ L+ ++ Sbjct: 64 QKKSEIVIGNITGSNIINIGIVIGITSLIYTI 95 >UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein - Haloarcula marismortui (Halobacterium marismortui) Length = 335 Score = 53.2 bits (122), Expect = 1e-05 Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 1/71 (1%) Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV-TEGDLGVGAVVGSAVF 167 YF A E + + + + GA +A SS PE+ + T + E LGVGA+VGSA+F Sbjct: 24 YFERAAERLSKYYGLPVAVHGAIVVAVGSSFPEISSVVISTVIHDEFSLGVGAIVGSAIF 83 Query: 168 NVLAVPACCAL 178 N+L +PA AL Sbjct: 84 NLLVIPALAAL 94 Score = 52.0 bits (119), Expect = 3e-05 Identities = 23/57 (40%), Positives = 36/57 (63%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 +G + P + GLT++AAGTSLP+A SV K ++N +GSNTF++L+ + Sbjct: 205 LGVIFDTPTFLWGLTVIAAGTSLPDAFVSVRAAKDDDSVTSLTNVLGSNTFNLLVAI 261 >UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=9; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter pomeroyi Length = 309 Score = 52.8 bits (121), Expect = 2e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 V L V D+ GLTI+A GTSLPE +SV+ + + + N +GSN F++L LG Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILG 249 Score = 44.8 bits (101), Expect = 0.004 Identities = 19/64 (29%), Positives = 35/64 (54%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + + L ++ G T +A +S PEL + + + + ++ VG +VGS +FNVL + Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGAT 251 Query: 177 ALFA 180 A+ A Sbjct: 252 AVIA 255 Score = 42.3 bits (95), Expect = 0.023 Identities = 22/59 (37%), Positives = 34/59 (57%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L +P + GLT++ GTS PE + SV +G + + N +GSN +ILL G+ L+ Sbjct: 31 LGLPPLLIGLTVVGFGTSTPELLVSVDAALRGVPDIALGNILGSNIANILLIGGITSLI 89 Score = 33.9 bits (74), Expect = 8.2 Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 8/118 (6%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + +RL + + G T + +S+PEL ++ D+ +G ++GS + N+L + Sbjct: 27 LAQRLGLPPLLIGLTVVGFGTSTPELLVSVDAALRGVPDIALGNILGSNIANILLIGGIT 86 Query: 177 AL---FAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 +L G + L W RD + L LL ++ L+L+L Y++ Sbjct: 87 SLIWPIRGKPVGL-W----RDLTVMILATLALTPILLGGQVIRVVGLVLLLSLVAYLV 139 >UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; Bacteria|Rep: Na+/Ca+ antiporter, CaCA family - Roseiflexus sp. RS-1 Length = 367 Score = 52.8 bits (121), Expect = 2e-05 Identities = 24/57 (42%), Positives = 37/57 (64%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 V + + GLTI+A GTSLPE +S++ +G + + N +GSN F++L LGL +V Sbjct: 210 VSELVIGLTIVAVGTSLPEIATSIVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVV 266 Score = 41.9 bits (94), Expect = 0.031 Identities = 22/60 (36%), Positives = 34/60 (56%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186 + G T +A +S PE+ + V E D+ VG VVGS +FN+L+V ++ A A I + Sbjct: 214 VIGLTIVAVGTSLPEIATSIVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVVAPAGISV 273 Score = 39.5 bits (88), Expect = 0.17 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQG-HGT-MGISNSIGSNTFDILLCLGL 398 L + + GLT++A GTS PE S+ G +G + + N +GSN ++LL LG+ Sbjct: 34 LGISPLVVGLTVVAFGTSAPELAVSIQSALSGPNGADVALGNVVGSNIANVLLILGI 90 Score = 34.3 bits (75), Expect = 6.2 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 7/118 (5%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFV--TEGDLGVGAVVGSAVFNVLAVPACCAL 178 L I+ + G T +A +S+PEL ++ D+ +G VVGS + NVL + A Sbjct: 34 LGISPLVVGLTVVAFGTSAPELAVSIQSALSGPNGADVALGNVVGSNIANVLLILGISAA 93 Query: 179 FAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL---VLMYTFYILEK 233 V++ + D + + + LD I + L+L ++ YT + + + Sbjct: 94 ITPLVVQQQ--LIRLDVPLMIGISVVVFVMALDGTISRIDGLILFAGIIAYTVFAIRQ 149 >UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23; Cyanobacteria|Rep: Ca2+/Na+ antiporter - Synechococcus sp. (strain WH7803) Length = 372 Score = 52.8 bits (121), Expect = 2e-05 Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L ++ + G T ++A +S PEL + V DL +G VVGS + N L V A+ A Sbjct: 205 LGVSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDLAIGNVVGSNLLNQLLVLGASAVAA 264 Query: 181 --GAVIELDWWSVTRDC-MMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINP 236 GA +++ + RD +M L + +I E +LV +Y FY+++++ P Sbjct: 265 AGGAGLQVSPMLIARDLPVMVLAALACLPIFWTRGQITRLEGGILVTLYVFYVVDQVLP 323 Score = 52.0 bits (119), Expect = 3e-05 Identities = 26/78 (33%), Positives = 45/78 (57%) Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 ++ I +G S ++ + L V ++ GLTI++AGTS+PE ++S++ +G + Sbjct: 181 VVGIVLLGVGSRVLVHGASAAATFLGVSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDL 240 Query: 380 GISNSIGSNTFDILLCLG 397 I N +GSN + LL LG Sbjct: 241 AIGNVVGSNLLNQLLVLG 258 Score = 50.8 bits (116), Expect = 7e-05 Identities = 23/60 (38%), Positives = 36/60 (60%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +P + GLT+++ GTS PE S+ QG + +SN +GSN F++++ LG LV L Sbjct: 38 IPQLVIGLTVVSFGTSAPELFVSLSSVTQGFDALAVSNVVGSNIFNVMVVLGSSALVMPL 97 Score = 37.9 bits (84), Expect = 0.50 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 7/138 (5%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 LL C L LL E FV + I + G T ++ +S+PELF++ Sbjct: 5 LLSCLEVLVGIALLFGGGE-LFVQGAVTLSLIFGIPQLVIGLTVVSFGTSAPELFVSL-- 61 Query: 149 TFVTEG--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 + VT+G L V VVGS +FNV+ V AL +E V RD + + Sbjct: 62 SSVTQGFDALAVSNVVGSNIFNVMVVLGSSALVMPLRVESR--LVRRDVPLLIAVSAAVW 119 Query: 207 LTLLDDKIYWHEALLLVL 224 ++ W + L+L Sbjct: 120 GMASAGRVTWQAGIALLL 137 >UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Roseobacter sp. CCS2|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Roseobacter sp. CCS2 Length = 326 Score = 52.8 bits (121), Expect = 2e-05 Identities = 24/65 (36%), Positives = 40/65 (61%) Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400 G + VP+++ G+T++A GTSLPE + + ++ + + N IGSNTF+IL + L Sbjct: 204 GSAIGVPEAVIGMTVVAFGTSLPELSTCIAAARKQSVGLILGNIIGSNTFNILSIIALTA 263 Query: 401 LVKSL 405 +K L Sbjct: 264 AIKPL 268 Score = 43.6 bits (98), Expect = 0.010 Identities = 21/46 (45%), Positives = 30/46 (65%) Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 G TI++ GTS+PE +SV QG+ + + N +GSN +ILL LG Sbjct: 50 GATIVSFGTSVPELFTSVNANLQGYPGISLGNVLGSNVANILLVLG 95 Score = 41.5 bits (93), Expect = 0.041 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F+L +A +LL+ D+ V A + ER ++ GAT ++ +S PELF + Sbjct: 10 FVLAAGAMAFGLYLLIKG--GDWTVDAAVFVAERTGLSPLFIGATIVSFGTSVPELFTSV 67 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 + +G V+GS V N+L V A + D + +D M ++ Sbjct: 68 NANLQGYPGISLGNVLGSNVANILLVLGATAFV--FKVTADPKHLAKDLAMMLFATAIMV 125 Query: 207 LTLLDDKIYWHEALLL-VLMYTFYILE 232 +L D L++ ++ TF + + Sbjct: 126 YGMLTDSFSQVFGLIMFAILVTFVVYQ 152 >UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; Erythrobacter|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Erythrobacter sp. NAP1 Length = 328 Score = 52.8 bits (121), Expect = 2e-05 Identities = 23/52 (44%), Positives = 35/52 (67%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 VP+++ GLT++A GTSLPE +S+ +G + I N +GSN ++ILL G Sbjct: 197 VPETVIGLTVVAIGTSLPELAASIAAALRGKSGLAIGNVLGSNIYNILLIGG 248 Score = 44.0 bits (99), Expect = 0.008 Identities = 24/63 (38%), Positives = 34/63 (53%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + L V TGL I+ TS+PE V+SV + G + N +GSN + LL LG+ Sbjct: 29 IAEKLGVSTLFTGLVIVGFATSMPEMVASVQASLAGSPEIAWGNIVGSNLANTLLILGVS 88 Query: 400 WLV 402 LV Sbjct: 89 ALV 91 >UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Rep: F7G19.17 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 546 Score = 52.8 bits (121), Expect = 2e-05 Identities = 25/81 (30%), Positives = 45/81 (55%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 + FIM + WI +++ + + +G L +P ++ GLT+LA G S+ + V+ V V K G Sbjct: 391 VAFIMSVFWISTIAGELLNCLAALGTLLKLPPALLGLTVLAWGNSVGDLVADVAVAKAGR 450 Query: 377 GTMGISNSIGSNTFDILLCLG 397 M ++ F++L+ LG Sbjct: 451 PAMAMAGCFAGPMFNMLVGLG 471 Score = 52.4 bits (120), Expect = 2e-05 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 1/137 (0%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L F +L + +F + +RLN++ +A T +A + +P++F + + Sbjct: 99 LILLHFYILIKTAQTHFSTVTTKLADRLNLSPSMAAVTLLALGNGAPDVFASVAALRGGQ 158 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 G GA++ + F V A++A A +D S RD + Y L L + Sbjct: 159 YRTGFGAILSAGTFVSAFVVGFVAIYA-APFPVDAASFVRDVLFYLIAALFLFYVYLSGE 217 Query: 214 IYWHEALLLVLMYTFYI 230 I+ +A+ V Y F++ Sbjct: 218 IFVWQAIGFVGFYIFFV 234 Score = 35.1 bits (77), Expect = 3.6 Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 336 IITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390 + T + D LN+ S+ +T+LA G P+ +SV + G G + + TF Sbjct: 118 VTTKLADRLNLSPSMAAVTLLALGNGAPDVFASVAALRGGQYRTGFGAILSAGTF 172 >UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 536 Score = 52.8 bits (121), Expect = 2e-05 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 3/175 (1%) Query: 59 VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHC-FLALYCFLLLGSVCEDYFVPAIEII 117 V ++ NC I +F + ++L L + F L +DY PA+ I Sbjct: 18 VYVKENCNDQEIFKFTHYYFCQLDENWVILILIAPLLFFFLFNFLARTVDDYLSPAVTFI 77 Query: 118 CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL-GVGAVVGSAVFNVLAVPACC 176 E ++ AG T +A A+ P+ F + + +G L VG++ GS + V Sbjct: 78 AEYFKMSQTFAGVTLIAFANGVPDFFCAVLASQDDDGILIAVGSIFGSCLCMTTLVFGAV 137 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 LF+G +I+ RD + L++ +I + A+ +Y YI+ Sbjct: 138 ILFSG-IIKAQKVPFIRDILFNGVAIFLLMVFAFIGQINHYMAIGFCSLYLVYIV 191 >UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=17; Rhodobacterales|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter pomeroyi Length = 319 Score = 52.4 bits (120), Expect = 2e-05 Identities = 22/69 (31%), Positives = 43/69 (62%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 ++L+ +++ T V +++ GLT++A GTSLPE ++V+ + + + N IGSN Sbjct: 192 AHLLVENASIIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNM 251 Query: 390 FDILLCLGL 398 F++L +G+ Sbjct: 252 FNLLAIIGV 260 Score = 51.2 bits (117), Expect = 5e-05 Identities = 27/62 (43%), Positives = 38/62 (61%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L VP I LTI+A GTS PE + S+ + + + N +GSNT +ILL LG+P L+ Sbjct: 32 LGVPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALLA 91 Query: 404 SL 405 +L Sbjct: 92 TL 93 Score = 42.7 bits (96), Expect = 0.018 Identities = 19/64 (29%), Positives = 33/64 (51%) Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 II ++ + G T +A +S PEL + + D+ +G V+GS +FN+LA+ Sbjct: 201 IIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNMFNLLAIIGV 260 Query: 176 CALF 179 +F Sbjct: 261 ATMF 264 Score = 35.1 bits (77), Expect = 3.6 Identities = 21/61 (34%), Positives = 30/61 (49%) Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALF 179 RL + + I T +A +S+PEL I+ + +G VVGS N+L V AL Sbjct: 31 RLGVPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALL 90 Query: 180 A 180 A Sbjct: 91 A 91 >UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Desulfovibrio desulfuricans G20|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Desulfovibrio desulfuricans (strain G20) Length = 339 Score = 52.4 bits (120), Expect = 2e-05 Identities = 30/76 (39%), Positives = 44/76 (57%) Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389 S LV T + L V + + GLTI+A GTSLPE V+ V+ + +G M + N IGS+ Sbjct: 208 SRLVVNGATAIAAWLGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMMLGNLIGSDL 267 Query: 390 FDILLCLGLPWLVKSL 405 F+ LG+ L++ L Sbjct: 268 FNFAGVLGITALLRPL 283 Score = 48.0 bits (109), Expect = 5e-04 Identities = 21/54 (38%), Positives = 35/54 (64%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + + + + GLTI+A GTSLPE + S G+ ++ ++N +GSN F++ L LG Sbjct: 34 VGISELVIGLTIVALGTSLPEFLVSFTAAVTGYSSISVANVVGSNIFNLGLILG 87 Score = 36.7 bits (81), Expect = 1.2 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Query: 93 FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 FLAL LL D V + R+ I+ + G T +A +S PE ++ Sbjct: 8 FLALGGLLLWFGA--DRLVEGASALARRVGISELVIGLTIVALGTSLPEFLVSFTAAVTG 65 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187 + V VVGS +FN+ + A+ + E D Sbjct: 66 YSSISVANVVGSNIFNLGLILGGVAMLRPVMPERD 100 Score = 35.1 bits (77), Expect = 3.6 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L ++ + G T +A +S PEL V +F ++ +G ++GS +FN V AL Sbjct: 222 LGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMMLGNLIGSDLFNFAGVLGITALL- 280 Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223 + +D ++ + L+L L ++ E LLL+ Sbjct: 281 -RPLSVDASALPNLALSVFTVLLILLLLRLRGRLGKAEGLLLL 322 >UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Prosthecochloris aestuarii DSM 271|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Prosthecochloris aestuarii DSM 271 Length = 334 Score = 52.4 bits (120), Expect = 2e-05 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Query: 314 IYPLTFIMCITWIGSVSYLV-AWIITV----VGDTLNVPDSITGLTILAAGTSLPEAVSS 368 I PL + + GSV AW + + LN+P GL+I+A GTSLPE +S Sbjct: 174 ILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATS 233 Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 ++ + + + N IGSN F+IL LG ++K Sbjct: 234 LVGAIRRESEISVGNLIGSNIFNILFVLGGVSMIK 268 Score = 46.4 bits (105), Expect = 0.001 Identities = 24/63 (38%), Positives = 36/63 (57%) Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 FV + I E+LNI G + +A +S PEL + VG E ++ VG ++GS +FN+ Sbjct: 198 FVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRRESEISVGNLIGSNIFNI 257 Query: 170 LAV 172 L V Sbjct: 258 LFV 260 Score = 39.9 bits (89), Expect = 0.13 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV-TKQGHGTMGI 381 + +IG+ +L+ + + G + + GLT++A GTS+PE V S + ++ + Sbjct: 24 LLFIGA-EWLIRGSVDLAGK-FGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSISL 81 Query: 382 SNSIGSNTFDILLCLGLPWLV 402 N IGSN +I L LGL L+ Sbjct: 82 GNVIGSNITNIGLILGLSALI 102 >UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1; uncultured marine bacterium EB0_49D07|Rep: K+-dependent Na+/Ca+ antiporter - uncultured marine bacterium EB0_49D07 Length = 313 Score = 52.4 bits (120), Expect = 2e-05 Identities = 23/53 (43%), Positives = 35/53 (66%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 L VP I GLTI+A GTSLPE ++++ ++G M + N IGSN F+++ + Sbjct: 192 LGVPQLIIGLTIIALGTSLPELAATIVALRKGKHQMVVGNIIGSNVFNLVFII 244 Score = 48.0 bits (109), Expect = 5e-04 Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 6/130 (4%) Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 FV +I + + I+ + G T +A +S+PE+F+ ++ +G +GS + N+ Sbjct: 24 FVDHASVIAKHMGISDLVIGLTLIAFGTSAPEIFVGISSIINQNEEIALGTAIGSNISNI 83 Query: 170 LAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEAL--LLVLMYT 227 + L+ + W+ + + L LTL+D KI ++E++ + +LM Sbjct: 84 ALIFGVSCLYLTEPSKTQLWNF----VPFGLSVVLLGLTLVDGKISFNESMGFVGILMIF 139 Query: 228 FYILEKINPL 237 ++L K + L Sbjct: 140 MFVLFKTDGL 149 Score = 38.3 bits (85), Expect = 0.38 Identities = 19/64 (29%), Positives = 33/64 (51%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 +V+ + + D + GLT++A GTS PE + + + + +IGSN +I L G Sbjct: 29 SVIAKHMGISDLVIGLTLIAFGTSAPEIFVGISSIINQNEEIALGTAIGSNISNIALIFG 88 Query: 398 LPWL 401 + L Sbjct: 89 VSCL 92 Score = 35.9 bits (79), Expect = 2.0 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 5/115 (4%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 L + I G T +A +S PEL V + + VG ++GS VFN++ + F Sbjct: 192 LGVPQLIIGLTIIALGTSLPELAATIVALRKGKHQMVVGNIIGSNVFNLVFIIPMIGFFG 251 Query: 181 GA-----VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 V++ D++ + M++ L I+ ++L+ Y YI Sbjct: 252 SVELSPMVMQRDFYILLVLSMVFILLAVVLTKLQFRKNIFSISGVVLIASYVLYI 306 >UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, expressed; n=6; Magnoliophyta|Rep: Magnesium/proton exchanger, putative, expressed - Oryza sativa subsp. japonica (Rice) Length = 523 Score = 52.4 bits (120), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 3/108 (2%) Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359 +L+A +P H + FI + +I ++Y V I + V + T LAAG Sbjct: 339 MLFAFVPPYEIAHGW--IAFICSLIFISGIAYGVTKITDQISCVTGVSPYVIAFTALAAG 396 Query: 360 TSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406 TS P+ V+S + +Q I+N SN+ +I + +G+PWLV +++ Sbjct: 397 TSWPDLVASKIAAERQITADSAITNITCSNSVNIYVGIGVPWLVDTMY 444 Score = 38.7 bits (86), Expect = 0.29 Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 13/117 (11%) Query: 127 IAGATFMAAASSSPELFINCVGTF-----VTEGDLGVGAVVGSAVFNVLAVPACCALF-- 179 IA +A +S P++ + + +T G LG G +VGSA F++ + A C + Sbjct: 88 IADVALLAFGTSFPQISLATIDAIRNLGQLTAGGLGPGTLVGSAAFDLFPIHAVCVVMPR 147 Query: 180 AGA---VIELDWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYIL 231 AG+ + +L W V + +IL + ++ W EALL VL Y +L Sbjct: 148 AGSKKKISDLGVWLVELFWSFWAYIWLYIILEVWTPRVITLW-EALLTVLQYGLLLL 203 >UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Pseudomonas syringae group|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Length = 343 Score = 52.0 bits (119), Expect = 3e-05 Identities = 32/87 (36%), Positives = 44/87 (50%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L LLL + V A +I L ++ I G T +A +S P L + + F E Sbjct: 162 LMLAAGLLLLTAGGHLLVDASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGE 221 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFA 180 D+ VG V+GS +FN+L V ALFA Sbjct: 222 RDIAVGNVIGSNLFNLLGVLGVTALFA 248 Score = 51.2 bits (117), Expect = 5e-05 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 V+ L + + I GLTI+A GTSLP ++S++ +G + + N IGSN F++L LG+ Sbjct: 184 VIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGV 243 Query: 399 PWLVKSLFYPSTPENHWVTDL 419 L + +P N V DL Sbjct: 244 TALFAPVPLTVSP-NAMVFDL 263 Score = 45.2 bits (102), Expect = 0.003 Identities = 18/52 (34%), Positives = 31/52 (59%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 + G T +A +S+P++ ++ F D+ VG+V+G +FNVL + CAL Sbjct: 32 LIGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLCAL 83 Score = 38.7 bits (86), Expect = 0.29 Identities = 18/53 (33%), Positives = 31/53 (58%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 + GLT++A GTS P+ S+ + + + + IG N F++L+ LGL L+ Sbjct: 32 LIGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLCALI 84 >UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Desulfuromonas acetoxidans DSM 684|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Desulfuromonas acetoxidans DSM 684 Length = 314 Score = 52.0 bits (119), Expect = 3e-05 Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 3/67 (4%) Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391 W+++ ++ ++ + + G+TI+A GTSLPE +S++ +G + I N IGSN F+ Sbjct: 188 WMVSSAVIIARSIGLSELFIGMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIFN 247 Query: 392 ILLCLGL 398 IL LG+ Sbjct: 248 ILFVLGV 254 Score = 47.6 bits (108), Expect = 6e-04 Identities = 23/78 (29%), Positives = 40/78 (51%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 ++ V + II + ++ G T +A +S PEL + + E D+ +G V+GS +F Sbjct: 187 NWMVSSAVIIARSIGLSELFIGMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIF 246 Query: 168 NVLAVPACCALFAGAVIE 185 N+L V C +F +E Sbjct: 247 NILFVLGVCPIFQPIAVE 264 Score = 42.7 bits (96), Expect = 0.018 Identities = 22/59 (37%), Positives = 34/59 (57%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408 I G+TI++ TS+PE + S+L +G + + N +GSN +I L LG L+ L P Sbjct: 39 IIGMTIVSFATSMPEMMVSLLAVGKGSSDIAVGNIVGSNIANIGLILGTSALLMPLNVP 97 Score = 34.7 bits (76), Expect = 4.7 Identities = 18/71 (25%), Positives = 33/71 (46%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V + + I G T ++ A+S PE+ ++ + D+ VG +VGS + Sbjct: 20 DFLVDGSSRLALSFGVRPLIIGMTIVSFATSMPEMMVSLLAVGKGSSDIAVGNIVGSNIA 79 Query: 168 NVLAVPACCAL 178 N+ + AL Sbjct: 80 NIGLILGTSAL 90 >UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Hyphomonas neptunium (strain ATCC 15444) Length = 339 Score = 52.0 bits (119), Expect = 3e-05 Identities = 25/60 (41%), Positives = 39/60 (65%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + +++ GLTI+A GTSLPE +SV+ + + + N IGSN F+IL LG+ LV+ Sbjct: 201 IGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILGITALVQ 260 Score = 48.4 bits (110), Expect = 4e-04 Identities = 23/59 (38%), Positives = 36/59 (61%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 V LN+ + + GLT++ GTS+PE V+S+ QG + I N +GSN ++LL L + Sbjct: 27 VARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVLLVLAI 85 Score = 44.8 bits (101), Expect = 0.004 Identities = 20/62 (32%), Positives = 35/62 (56%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + ++ I+ + G T +A +S PEL + V F + D+ +G V+GS +FN+L + Sbjct: 197 LARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILGIT 256 Query: 177 AL 178 AL Sbjct: 257 AL 258 Score = 36.7 bits (81), Expect = 1.2 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 2/96 (2%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +++ +A FLL V + V + +LNI+ + G T + +S PEL + Sbjct: 1 MMYLMIAAGLFLLF--VGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQA 58 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 + +G VVGS + NVL V A + + ++ Sbjct: 59 VGQGAVGISIGNVVGSNIANVLLVLAIAVILSPIIV 94 >UniRef50_O83997 Cluster: Conserved hypothetical integral membrane protein; n=1; Treponema pallidum|Rep: Conserved hypothetical integral membrane protein - Treponema pallidum Length = 341 Score = 51.6 bits (118), Expect = 4e-05 Identities = 20/52 (38%), Positives = 34/52 (65%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 VP I TI+A GTS+PE VS++ ++GHG + + N +G++ ++L +G Sbjct: 222 VPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAVGNIVGADILNVLFVVG 273 Score = 45.2 bits (102), Expect = 0.003 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158 FL+LGS +P +EI+ R + + I AT +A +S PEL G L V Sbjct: 201 FLVLGS---RVLIPTVEIMALRAGVPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAV 257 Query: 159 GAVVGSAVFNVLAVPACCA 177 G +VG+ + NVL V A Sbjct: 258 GNIVGADILNVLFVVGAAA 276 Score = 39.1 bits (87), Expect = 0.22 Identities = 18/53 (33%), Positives = 30/53 (56%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + +++ G T+++ GT+ PEA SV G+ + + N+IGS D LGL Sbjct: 48 ISEALLGATLVSLGTTTPEAAVSVYAALCGNADLALGNAIGSIVVDTGFILGL 100 Score = 37.9 bits (84), Expect = 0.50 Identities = 23/92 (25%), Positives = 40/92 (43%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155 L C L + D V + + R I+ + GAT ++ +++PE ++ D Sbjct: 21 LLCALYFLARSADCLVESASALSRRWGISEALLGATLVSLGTTTPEAAVSVYAALCGNAD 80 Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187 L +G +GS V + + AL A + LD Sbjct: 81 LALGNAIGSIVVDTGFILGLGALLARPGLALD 112 >UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor; n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter, CaCA family precursor - Ruthia magnifica subsp. Calyptogena magnifica Length = 317 Score = 51.6 bits (118), Expect = 4e-05 Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Query: 318 TFIMCITWIGSV---SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374 T+IM I + S+ + LV W V V D I GL+++A GT LPE S+ + Sbjct: 173 TWIMLIVNLVSLISSAKLVVWGSIEVAKVFGVSDLIIGLSVVALGTGLPELAVSITSVLK 232 Query: 375 GHGTMGISNSIGSNTFDILLCLGLPWLV 402 M I N IGSN F+ + L +P L+ Sbjct: 233 KQYAMVIGNVIGSNLFNTIAVLAIPGLI 260 Score = 48.8 bits (111), Expect = 3e-04 Identities = 24/68 (35%), Positives = 37/68 (54%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + + + I GL I GTS PE + S L +G+ + I N+IGSN F+I L LG Sbjct: 30 TKIANIFKISPLIIGLIIFGFGTSTPEMLVSALAAIEGNTGLSIGNAIGSNIFNISLVLG 89 Query: 398 LPWLVKSL 405 + ++ + Sbjct: 90 ISAIISPI 97 Score = 34.3 bits (75), Expect = 6.2 Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 ILL L F+LL D F I I+ I G +S+PE+ ++ + Sbjct: 4 ILLPIIALLSGFVLL-IWSADKFTENGTKIANIFKISPLIIGLIIFGFGTSTPEMLVSAL 62 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207 L +G +GS +FN+ V A+ + ++ D + ++ + L L Sbjct: 63 AAIEGNTGLSIGNAIGSNIFNISLVLGISAIISPIEVQGDVFK--KEWLFLMVVTLCLGL 120 Query: 208 TLLDDKIYWHEAL----LLVLMYTFYILEKINPL 237 L D ++ + + + LLVL + + I + N + Sbjct: 121 LLWDYRLDFTDGMILLSLLVLFFAYTIKQAKNKM 154 >UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like protein; n=1; Salinibacter ruber DSM 13855|Rep: K+-dependent Na+/Ca+ exchanger-like protein - Salinibacter ruber (strain DSM 13855) Length = 317 Score = 51.2 bits (117), Expect = 5e-05 Identities = 23/58 (39%), Positives = 36/58 (62%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + D LN+ + GLT++A GTSLPE +S++ T + M + N IGSN ++L +G Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVG 257 Score = 46.0 bits (104), Expect = 0.002 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I + LNI + G T +A +S PEL + VGT E D+ VG V+GS + NVL V Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVGTL 259 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 A+ ++ + + M+ + LT D KI E +V+ + +++ Sbjct: 260 AIAEPITVDPETIRLHFPVML-GFCALLVPLTWWDQKITRVEGAFMVIAFLGFMV 313 Score = 44.4 bits (100), Expect = 0.006 Identities = 21/48 (43%), Positives = 29/48 (60%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 I GLT++A GTS+PE + +V G + I N IGSN ++ L LG Sbjct: 39 ILGLTVVALGTSMPEYLVNVFALISGESPLAIGNIIGSNISNVALILG 86 Score = 41.5 bits (93), Expect = 0.041 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 ++L+ FL LLL E A I + I I G T +A +S PE +N Sbjct: 1 MILYVFLFFVGLLLLYLGAEGLIQGASSIALQ-YGIRPVILGLTVVALGTSMPEYLVNVF 59 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 E L +G ++GS + NV + CA+ Sbjct: 60 ALISGESPLAIGNIIGSNISNVALILGACAV 90 >UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; Salinispora|Rep: Na+/Ca+ antiporter, CaCA family - Salinispora tropica CNB-440 Length = 352 Score = 51.2 bits (117), Expect = 5e-05 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Query: 304 TIPDCRHRHSIY-PLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSL 362 T P R R + + P+ ++ + + + + L+ + L VP + G+T++A GTSL Sbjct: 198 TEPTPRQRPARWEPVRTVLGLVGVLAGAQLLVVNAAAIATDLGVPQLVIGMTLVAVGTSL 257 Query: 363 PEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 PE V+++ +QG + + N GSN F+ L Sbjct: 258 PELVTTIQAQRQGESDLLVGNLFGSNLFNSL 288 Score = 44.4 bits (100), Expect = 0.006 Identities = 27/101 (26%), Positives = 45/101 (44%) Query: 85 HGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFI 144 H I+L L LLL +V D+ V + RL I + G + +S+PEL + Sbjct: 19 HERIMLIRILLAVAGLLLLTVAADHLVLGASRLAHRLRIRPVVVGVVVIGLGTSAPELLV 78 Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185 + V + + +G + GS + N+ V AL A ++ Sbjct: 79 SGVAAARDDTSIAMGNIAGSNILNLTMVLGVAALVAKVTVK 119 Score = 37.1 bits (82), Expect = 0.88 Identities = 18/67 (26%), Positives = 34/67 (50%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + + G+ ++ GTS PE + S + + ++ + N GSN ++ + LG+ LV Sbjct: 55 LRIRPVVVGVVVIGLGTSAPELLVSGVAAARDDTSIAMGNIAGSNILNLTMVLGVAALVA 114 Query: 404 SLFYPST 410 + ST Sbjct: 115 KVTVKST 121 Score = 34.7 bits (76), Expect = 4.7 Identities = 23/68 (33%), Positives = 30/68 (44%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I L + + G T +A +S PEL E DL VG + GS +FN LA A Sbjct: 235 IATDLGVPQLVIGMTLVAVGTSLPELVTTIQAQRQGESDLLVGNLFGSNLFNSLAGGAVI 294 Query: 177 ALFAGAVI 184 A A + Sbjct: 295 AFAAPTTV 302 >UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Petrotoga mobilis SJ95|Rep: Na+/Ca+ antiporter, CaCA family - Petrotoga mobilis SJ95 Length = 320 Score = 51.2 bits (117), Expect = 5e-05 Identities = 22/64 (34%), Positives = 41/64 (64%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + ++ + +S+ G+TI+A GTSLPE V++++ + + + N +GSNTF+I LG+ Sbjct: 199 IFAKSIGISESLIGVTIVAVGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGI 258 Query: 399 PWLV 402 L+ Sbjct: 259 SALI 262 Score = 45.2 bits (102), Expect = 0.003 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 1/59 (1%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L V + GLT++A GTS PE V ++ + +G ++G+ N +GSN +I L LG+ +L+ Sbjct: 32 LGVSELFAGLTVVAFGTSAPELVVTISSSIKG-ASVGLGNVLGSNVANIGLILGISFLI 89 Score = 44.0 bits (99), Expect = 0.008 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 2/108 (1%) Query: 75 SDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMA 134 ++ + + +++ + + F AL +L+ + + V I + + I+ + G T +A Sbjct: 160 NEEMKKVEKEESWAKIITFSALGLAMLI--IGGELTVSNAVIFAKSIGISESLIGVTIVA 217 Query: 135 AASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 +S PEL V D+ +G +VGS FN+ A+ AL GA Sbjct: 218 VGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGISALINGA 265 Score = 35.9 bits (79), Expect = 2.0 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 +AL FLL+ D + + +L ++ AG T +A +S+PEL + + + + Sbjct: 7 IALGIFLLIRGA--DRLIEGALGLTRKLGVSELFAGLTVVAFGTSAPELVVT-ISSSIKG 63 Query: 154 GDLGVGAVVGSAVFNV 169 +G+G V+GS V N+ Sbjct: 64 ASVGLGNVLGSNVANI 79 >UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger - Algoriphagus sp. PR1 Length = 312 Score = 51.2 bits (117), Expect = 5e-05 Identities = 22/60 (36%), Positives = 37/60 (61%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 V + + G+TI+A GTSLPE ++S++ M I N +GSN ++L LG+ ++K + Sbjct: 202 VSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMNVLSILGITAIIKPI 261 Score = 48.0 bits (109), Expect = 5e-04 Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + + GLTI+A GTS PE + SV +G+ + + N IGSN +I + LG + Sbjct: 32 LGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDISVGNVIGSNIANIGMVLG----IS 87 Query: 404 SLFYPSTPENHWVTDLYFIRI 424 LFYP + YFI + Sbjct: 88 GLFYPILIRKSTLRFDYFITV 108 Score = 39.5 bits (88), Expect = 0.17 Identities = 20/69 (28%), Positives = 34/69 (49%) Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 V I +L +++ + G T +A +S+PEL ++ D+ VG V+GS + N+ Sbjct: 22 VDGASAIAVKLGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDISVGNVIGSNIANIG 81 Query: 171 AVPACCALF 179 V LF Sbjct: 82 MVLGISGLF 90 Score = 39.1 bits (87), Expect = 0.22 Identities = 24/116 (20%), Positives = 54/116 (46%), Gaps = 5/116 (4%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I ++ + G T +A +S PEL + + + D+ +G ++GS + NVL++ Sbjct: 196 ISREFGVSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMNVLSILGIT 255 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK--IYWHEALLLVLMYTFYI 230 A+ + ++ + ++ ++ L+ K I + E L+L++ Y Y+ Sbjct: 256 AIIKPIGVSDEF---LQSDFLWMIGFTLILFPLIRTKMRISFIEGLILLIGYCTYL 308 >UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter thermautotrophicus|Rep: ORF318 - Methanobacterium thermoformicicum Length = 160 Score = 50.8 bits (116), Expect = 7e-05 Identities = 25/63 (39%), Positives = 38/63 (60%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + D +P I GL LA GTS+PE V ++ +G + I +GSNTF+IL+ +G+P Sbjct: 39 LADIAGIPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVP 98 Query: 400 WLV 402 L+ Sbjct: 99 ALI 101 Score = 37.1 bits (82), Expect = 0.88 Identities = 27/112 (24%), Positives = 48/112 (42%) Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182 I + I G +A +S PEL + +L +G V+GS FN+L AL A Sbjct: 45 IPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVPALIAPV 104 Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKI 234 +E M+ L++ D K+ ++L+ +Y Y++ ++ Sbjct: 105 PVEPLSLRFDAPIMILVTVLLVLLIKQGDMKLKRSGGIILLAVYISYVVMRL 156 >UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+ antiporter, CaCA family - Halorubrum lacusprofundi ATCC 49239 Length = 326 Score = 50.8 bits (116), Expect = 7e-05 Identities = 24/60 (40%), Positives = 37/60 (61%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 V D G TI+AAGTS PE S++ ++GH M + N +GSN F++L +G+ ++ L Sbjct: 212 VSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVGNVVGSNVFNVLGIMGIAAFLRPL 271 Score = 49.2 bits (112), Expect = 2e-04 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 2/79 (2%) Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384 WIG+ + + A + V V + GLTI+A GTS PE V +V G G +G+ N Sbjct: 21 WIGARALVDATVR--VARRFGVGELTIGLTIVAMGTSTPELVVTVDAALAGLGEIGVGNI 78 Query: 385 IGSNTFDILLCLGLPWLVK 403 IGSN +++ LG L++ Sbjct: 79 IGSNAYNLAFILGAVSLLR 97 Score = 44.8 bits (101), Expect = 0.004 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 L L V + V A + ++ G T +AA +S+PEL ++ V + VG Sbjct: 189 LALVLVSGHFMVEAASTLARSAGVSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVG 248 Query: 160 AVVGSAVFNVLAVPACCALF-----AGAVIELDWW 189 VVGS VFNVL + A GA IE W Sbjct: 249 NVVGSNVFNVLGIMGIAAFLRPLAVGGAAIETVLW 283 Score = 40.3 bits (90), Expect = 0.095 Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 2/119 (1%) Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170 V A + R + G T +A +S+PEL + G++GVG ++GS +N+ Sbjct: 28 VDATVRVARRFGVGELTIGLTIVAMGTSTPELVVTVDAALAGLGEIGVGNIIGSNAYNLA 87 Query: 171 AVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 + +L VI ++ V RD L D + E LL ++ Y Sbjct: 88 FILGAVSLL--RVIPVERSLVHRDGAALVLSTLVGAAALFDRTVTGVEGALLAGLFVAY 144 >UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; Aquifex aeolicus|Rep: Putative uncharacterized protein - Aquifex aeolicus Length = 322 Score = 50.4 bits (115), Expect = 9e-05 Identities = 26/65 (40%), Positives = 39/65 (60%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +P+ + GLT++A GTSLPE +V + + + N IGSN +ILL LG+ L+K L Sbjct: 35 IPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGISLGNVIGSNIANILLILGVASLIKPL 94 Query: 406 FYPST 410 +T Sbjct: 95 TVHAT 99 Score = 49.6 bits (113), Expect = 2e-04 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%) Query: 311 RHSIYPLT-FIMCITWIGSVSYLVAWIIT-VVG--DTLNVPDSITGLTILAAGTSLPEAV 366 + SI P FI I + +S W + VG L V +++ GL ++A GTSLPE Sbjct: 166 KESISPFKGFIYFILGLTGLSLGADWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELF 225 Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408 +S + +G+ + + N GSN F+ L LG +++ + P Sbjct: 226 ASAVSAYKGNPDIALGNVAGSNIFNATLVLGTSSVIRDIPVP 267 Score = 39.1 bits (87), Expect = 0.22 Identities = 20/69 (28%), Positives = 34/69 (49%) Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163 S+ D+ V + + L ++ + G +A +S PELF + V + D+ +G V G Sbjct: 186 SLGADWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAG 245 Query: 164 SAVFNVLAV 172 S +FN V Sbjct: 246 SNIFNATLV 254 Score = 35.5 bits (78), Expect = 2.7 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L FLL+ D + + R I + G T +A +S PE +N Sbjct: 8 LTLGFFLLVKGA--DMLIEGAGGLARRFGIPEFVIGLTLVAFGTSLPEFTVNVSAALKDA 65 Query: 154 GDLGVGAVVGSAVFNVLAVPACCAL 178 + +G V+GS + N+L + +L Sbjct: 66 SGISLGNVIGSNIANILLILGVASL 90 >UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=9; Bacteroidetes|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Flavobacteria bacterium BBFL7 Length = 317 Score = 50.4 bits (115), Expect = 9e-05 Identities = 30/112 (26%), Positives = 53/112 (47%) Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALF 179 +L ++ I G T ++ A+S+PEL ++ L +G V+GS + N+ V AL Sbjct: 30 KLRLSRMIIGLTVVSFATSAPELIVSIQSALDGFSGLAIGNVIGSNIANIALVLGATALI 89 Query: 180 AGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 A I+ D++ MM ++L ++ + W +LL + F IL Sbjct: 90 APLAIDKDFFKFNWPWMMAFSILLYILLLSDNNLVRWEGGILLGSIIVFLIL 141 Score = 50.0 bits (114), Expect = 1e-04 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384 W GS LV + + +L +P+SI ++++A GTS+PE +S++ + + + N Sbjct: 179 WQGS-ELLVKGAVDIAA-SLGIPESIIAVSMVALGTSVPELAASIIAALKKEKAISLGNL 236 Query: 385 IGSNTFDILLCLGLPWLVKSL 405 IGSN F+I LG+ L++ + Sbjct: 237 IGSNIFNIGSVLGITALIQPI 257 Score = 41.9 bits (94), Expect = 0.031 Identities = 23/62 (37%), Positives = 32/62 (51%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 L + I GLT+++ TS PE + S+ G + I N IGSN +I L LG L+ Sbjct: 31 LRLSRMIIGLTVVSFATSAPELIVSIQSALDGFSGLAIGNVIGSNIANIALVLGATALIA 90 Query: 404 SL 405 L Sbjct: 91 PL 92 Score = 37.5 bits (83), Expect = 0.67 Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 8/143 (5%) Query: 96 LYCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV 151 ++ FL LG + + V I L I I + +A +S PEL + + Sbjct: 167 IFMFLALGGLALWQGSELLVKGAVDIAASLGIPESIIAVSMVALGTSVPELAASIIAALK 226 Query: 152 TEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTL-L 210 E + +G ++GS +FN+ +V AL I+ + + + + + +L L Sbjct: 227 KEKAISLGNLIGSNIFNIGSVLGITALIQPIQIQPEGMGLLNNDIFWMLGISFALLPLAF 286 Query: 211 DDKIYW---HEALLLVLMYTFYI 230 K+Y ++ +L + Y +I Sbjct: 287 LPKVYHISRYKGILFLAAYLLFI 309 >UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=2; delta proteobacterium MLMS-1|Rep: K+-dependent Na+/Ca+ exchanger related-protein - delta proteobacterium MLMS-1 Length = 351 Score = 50.4 bits (115), Expect = 9e-05 Identities = 23/67 (34%), Positives = 38/67 (56%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 + + + + GLT+ A GTSLPE + +Q T+ + N IGSN F++L+ LG+ + Sbjct: 239 MGISELVIGLTLAAIGTSLPELATCFAAIRQRQDTLLVGNIIGSNIFNLLMVLGITGTLL 298 Query: 404 SLFYPST 410 P+T Sbjct: 299 PFALPAT 305 Score = 35.9 bits (79), Expect = 2.0 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 4/59 (6%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408 + GLT++A GTSLPE ++ + +G + + N IGSN +I GL + LF+P Sbjct: 79 LIGLTVVAFGTSLPELFIALGASWRGVPGIMLGNVIGSNIANI----GLILAISLLFFP 133 >UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 682 Score = 50.4 bits (115), Expect = 9e-05 Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 3/139 (2%) Query: 93 FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 FL L CF L+G++ D+ P + I + L ++ +AG TF+A + +P++ + Sbjct: 97 FLIL-CFTLVGTIASDFLCPNLYTISKILRLSDRLAGLTFLALGNGAPDVLGTYKAMSMN 155 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 L V +VG+A F V A+ ++ D S D + + + ++ Sbjct: 156 TESLAVSELVGAAFFATTIVVGLIAVIHPFEVKRD--SFIIDFGFFLLAAMVVFVAIVRS 213 Query: 213 KIYWHEALLLVLMYTFYIL 231 + +L L L+Y Y+L Sbjct: 214 TLSIWTSLSLCLIYLSYVL 232 Score = 44.0 bits (99), Expect = 0.008 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 304 TIPDCRHRHSIYP--LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTS 361 TIP C+H + F+ I WI + + I + + N+ D I GLT+ A G S Sbjct: 510 TIPSCKHYIIMTGSLFGFVSSICWIALFATEIISIFQAIATSYNLSDDILGLTVFAWGNS 569 Query: 362 LPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + + +S+ + + G M G+ + L LG+ Sbjct: 570 VGDLISNFTIARMGLPLMAFGACFGAPLLSLCL-LGI 605 >UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30; Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo sapiens (Human) Length = 584 Score = 50.4 bits (115), Expect = 9e-05 Identities = 27/87 (31%), Positives = 47/87 (54%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F+ WI + + V I+ +G + +++ GLT+LA G S+ +A S + +QG+ Sbjct: 424 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 483 Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403 M S G F+IL+ +GL L++ Sbjct: 484 PRMAFSACFGGIIFNILVGVGLGCLLQ 510 Score = 49.6 bits (113), Expect = 2e-04 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 3/148 (2%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 + L+ LY FL+LG +F P + I L ++ ++AG TF+A + +P++F V Sbjct: 100 VTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALV 159 Query: 148 G-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 + L +GA+ G+ V V + + RD + Y Sbjct: 160 AFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASR--PFFRDIVFYMVAVFLTF 217 Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKI 234 L L ++ AL + +Y FY++ I Sbjct: 218 LMLFRGRVTLAWALGYLGLYVFYVVTVI 245 >UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Na/Ca,K-exchanger - Entamoeba histolytica HM-1:IMSS Length = 575 Score = 50.0 bits (114), Expect = 1e-04 Identities = 25/118 (21%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344 +++ +V WP+ +IL TIPD + + + P+T ++ + +IG +++ + + + + Sbjct: 378 QRIVYVFNWPLLVILAYTIPDVKIKTCARMTPVTILISLLYIGVFAFVGVFCGYRLSEVI 437 Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 P + G T +A S+ +S + + + I NS + F + + +PW++ Sbjct: 438 TCPPDVLGFTFVALFLSIRHIISGWVSGRMMCANLAILNSYSMSLFFTNVAIVIPWMI 495 >UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14779, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 880 Score = 50.0 bits (114), Expect = 1e-04 Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377 F + I+ IG ++ + + + G T+ + DS+T + +A GTS+P+ S V + + Sbjct: 712 FFVSISLIGVLTAITGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYA 771 Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSL 405 I N GSN ++ L +G+ W + ++ Sbjct: 772 DASIGNVTGSNAVNVFLGIGVAWTIAAV 799 Score = 38.7 bits (86), Expect = 0.29 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 ++ T MA SS+PE+ ++ + G G LG +VGSA FN+ + A C Sbjct: 77 VSNLTLMALGSSAPEILLSVIEVCGHNFESGALGPSTIVGSAAFNMFVIIAIC 129 >UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family; n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+ antiporter, CaCA family - Sulfurovum sp. (strain NBC37-1) Length = 310 Score = 50.0 bits (114), Expect = 1e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 N+P+ I G T++A GTSLPE +S+ + + ISN IGSN +I L L +L+ Sbjct: 32 NIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLASVFLI 89 Score = 45.2 bits (102), Expect = 0.003 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%) Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174 E I + NI I GAT +A +S PE+ + + + ++ + V+GS + N+ V A Sbjct: 25 EKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLA 84 Query: 175 CCALFAGAVI-ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 L A + + D+++ +D IL +LD I +A+LL+L+ Y+L Sbjct: 85 SVFLIARNISPKRDFFA--KDSTWALVPVLVFILMILDGVISRFDAVLLLLLMGAYLL 140 Score = 41.1 bits (92), Expect = 0.054 Identities = 18/58 (31%), Positives = 32/58 (55%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 + + + + + G+ +++ GTS+PE V S+ +G M I N IGSN + + LG Sbjct: 192 IAKSFGISEWVIGIVMISLGTSMPELVVSISAAMKGKVDMAIGNIIGSNLANTTVVLG 249 >UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneumophila|Rep: Na/Ca antiporter - Legionella pneumophila (strain Corby) Length = 319 Score = 50.0 bits (114), Expect = 1e-04 Identities = 23/51 (45%), Positives = 35/51 (68%) Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 GLTI+A G+SLPE +S++ +G ++ I IGSN +++LL L LP L+ Sbjct: 209 GLTIIAIGSSLPELTTSLVAAIKGEDSIAIGTIIGSNIYNLLLILALPGLL 259 Score = 45.2 bits (102), Expect = 0.003 Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L++ LL+ +C Y V I + I+ G T +A SS PEL + V E Sbjct: 174 LSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGE 233 Query: 154 GDLGVGAVVGSAVFNVLAVPA 174 + +G ++GS ++N+L + A Sbjct: 234 DSIAIGTIIGSNIYNLLLILA 254 Score = 44.8 bits (101), Expect = 0.004 Identities = 23/52 (44%), Positives = 33/52 (63%) Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 GLTI+A GTS PE S++ + + + I N+IGSN +I L LG+ L+K Sbjct: 40 GLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANIGLILGIIILIK 91 Score = 39.9 bits (89), Expect = 0.13 Identities = 16/50 (32%), Positives = 30/50 (60%) Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 R ++ + G T +A +S+PELFI+ + + + DL +G +GS + N+ Sbjct: 31 RFQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANI 80 >UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091; n=9; Methanococcales|Rep: Uncharacterized membrane protein MJ0091 - Methanococcus jannaschii Length = 302 Score = 50.0 bits (114), Expect = 1e-04 Identities = 25/123 (20%), Positives = 62/123 (50%), Gaps = 4/123 (3%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+FV E I N+++ + GAT MA +S PE+ + +++ + +G +GS + Sbjct: 21 DWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCIC 80 Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227 N+ V A+ + +++ ++ ++ ++Y + +D W + ++L++++ Sbjct: 81 NIGLVLGLSAIISPIIVDK---NLQKNILVYLLFVIFAAVIGIDG-FSWIDGVVLLILFI 136 Query: 228 FYI 230 Y+ Sbjct: 137 IYL 139 Score = 48.0 bits (109), Expect = 5e-04 Identities = 36/102 (35%), Positives = 50/102 (49%), Gaps = 9/102 (8%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGD-----TLNVPDSITGLTILAAGTSLPEAVSSVLV 371 + F + + IG + LV + V G L++ D + G T++A GTSLPE + S+ Sbjct: 161 VVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAA 220 Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413 K+ G M + N IGSN DI G V SLF EN Sbjct: 221 AKRNLGGMVLGNVIGSNIADI----GGALAVGSLFMHLPAEN 258 Score = 44.0 bits (99), Expect = 0.008 Identities = 24/78 (30%), Positives = 41/78 (52%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 NV + + G T++A GTSLPE ++S + + I N+IGS +I L LGL ++ Sbjct: 35 NVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISP 94 Query: 405 LFYPSTPENHWVTDLYFI 422 + + + + L F+ Sbjct: 95 IIVDKNLQKNILVYLLFV 112 Score = 35.1 bits (77), Expect = 3.6 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Query: 94 LALYCFLLLGS-VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 L L L+G V + FV + I L+I+ + G T +A +S PEL ++ Sbjct: 165 LVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRN 224 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALF 179 G + +G V+GS + ++ A +LF Sbjct: 225 LGGMVLGNVIGSNIADIGGALAVGSLF 251 >UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute carrier family 24 member 6; n=1; Apis mellifera|Rep: PREDICTED: similar to solute carrier family 24 member 6 - Apis mellifera Length = 451 Score = 49.6 bits (113), Expect = 2e-04 Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364 IP + + + M + ++ V+ V ++ VG ++ D++ G+T+LA G S+ + Sbjct: 270 IPKFHNAFAFFGFFTAMMVVYL--VAKEVMAVLQCVGYAFSISDAMLGITLLAWGNSIGD 327 Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409 +++V + +QG MG + G F+ LL LGL + V++ P+ Sbjct: 328 LIANVTIARQGFPRMGYAACFGGPMFNTLLGLGLTYGVEAAKDPN 372 >UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14681, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 473 Score = 49.2 bits (112), Expect = 2e-04 Identities = 25/57 (43%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVG 341 K+L ++L PI L LW T+PD R S +P+TF+ I WI SYL+ W VG Sbjct: 135 KRLTYLLIVPIVLPLWLTLPDVRKPSSKKFFPITFLGAICWIAFFSYLMVWWAHQVG 191 >UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=1; Silicibacter sp. TM1040|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Silicibacter sp. (strain TM1040) Length = 327 Score = 49.2 bits (112), Expect = 2e-04 Identities = 20/51 (39%), Positives = 34/51 (66%) Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393 + + +++ GLTI+A GTS+PE V+SV+ + G + N +GSN ++IL Sbjct: 212 SFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNIL 262 Score = 47.2 bits (107), Expect = 8e-04 Identities = 41/179 (22%), Positives = 70/179 (39%) Query: 2 LIRTRQYERKHRVATIVRVVLFFGIPIVYMVAKSIASNQVIVFDEPEAFSSRHLLGIVEI 61 +I R R+ V ++ ++F G+ V+ + + + +I F R + Sbjct: 94 IIVARAALRRDAVVMLLAALVFSGLAAVWPMGRLSGAALIIAMIGYITFVVRQERQNADT 153 Query: 62 ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121 L + GL Q + G L L L+L V V + Sbjct: 154 GALHDKGEALAGAAPGLDPAQTKSGRGLAVSLLLALGGLVLVVVGGAALVNGAVALARSF 213 Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 I+ + G T +A +S PEL + + +GD+ G VVGS ++N+L + AL A Sbjct: 214 EISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNILGIGGTTALIA 272 Score = 41.9 bits (94), Expect = 0.031 Identities = 23/59 (38%), Positives = 32/59 (54%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L V + GLT++ GTS PE V+SV G + N +GSN +ILL G+ L+ Sbjct: 33 LGVSPLVIGLTLVGFGTSTPELVTSVQAGLSGAPGIAYGNVVGSNIANILLIAGISALL 91 Score = 34.7 bits (76), Expect = 4.7 Identities = 25/96 (26%), Positives = 39/96 (40%) Query: 89 LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148 +L L L L L V D V RL ++ + G T + +S+PEL + Sbjct: 1 MLEIGLLLVVGLALLMVGGDLLVRGAVQAAARLGVSPLVIGLTLVGFGTSTPELVTSVQA 60 Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184 + G VVGS + N+L + AL ++ Sbjct: 61 GLSGAPGIAYGNVVGSNIANILLIAGISALLCPIIV 96 >UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-protein; n=4; Chlorobium|Rep: K+-dependent Na+/Ca+ exchanger related-protein - Chlorobium ferrooxidans DSM 13031 Length = 318 Score = 49.2 bits (112), Expect = 2e-04 Identities = 21/68 (30%), Positives = 39/68 (57%) Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397 T + + + G T++A GTS+PE SS++ +GH +G+ +GSN F+ LL +G Sbjct: 188 TAIALAFGMDKFLIGATVVALGTSMPELASSLIAKYRGHDEVGLGTILGSNIFNGLLIVG 247 Query: 398 LPWLVKSL 405 + ++ + Sbjct: 248 VTAMINPI 255 Score = 45.2 bits (102), Expect = 0.003 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 3/105 (2%) Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186 + GAT +A +S PEL + + + ++G+G ++GS +FN L + A+ + L Sbjct: 200 LIGATVVALGTSMPELASSLIAKYRGHDEVGLGTILGSNIFNGLLIVGVTAMINPIQVTL 259 Query: 187 DWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 T ++ L L D +I + + L+++Y Y++ Sbjct: 260 ---RETGTALLIGITALLLTFPLSDGRIKKSQGVFLIMLYAGYLI 301 Score = 41.9 bits (94), Expect = 0.031 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 6/139 (4%) Query: 97 YCFLLLG----SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152 Y +LL G ++ D FV I IA I GAT A A+S+PEL + Sbjct: 4 YAYLLFGILFAALGGDLFVRGAVGIASSFRIAPGIIGATVAAFATSTPELSVAVNAGIAG 63 Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 + +G +GS + N+ + +G I+ ++ RD + + LLD Sbjct: 64 SPQIAMGDALGSNIVNIAFILGIVLAISG--IDAPQDTIRRDYTVALLVPVITGILLLDG 121 Query: 213 KIYWHEALLLVLMYTFYIL 231 + + L+V ++ F+ L Sbjct: 122 LVSRLDGFLMVSIFLFWFL 140 >UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1; Thermococcus kodakarensis KOD1|Rep: Sodium/calcium antiporter - Pyrococcus kodakaraensis (Thermococcus kodakaraensis) Length = 311 Score = 49.2 bits (112), Expect = 2e-04 Identities = 22/66 (33%), Positives = 40/66 (60%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + L V + + G TI+A GTSLPE +++ + G++ + N IG+N + L+ LGL Sbjct: 192 IAEALGVAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLA 251 Query: 400 WLVKSL 405 L++ + Sbjct: 252 SLIRPI 257 Score = 41.1 bits (92), Expect = 0.054 Identities = 20/62 (32%), Positives = 31/62 (50%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I E L +A + GAT +A +S PE+ G G + VG ++G+ + N L V Sbjct: 192 IAEALGVAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLA 251 Query: 177 AL 178 +L Sbjct: 252 SL 253 Score = 34.7 bits (76), Expect = 4.7 Identities = 19/69 (27%), Positives = 35/69 (50%) Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396 I V + V I L +++ T+LPE +S + + + + N++GS +I L L Sbjct: 28 IVEVAEKAGVSPLIISLVVISLATTLPEITTSAMASITKAEGIALGNALGSIFANIALIL 87 Query: 397 GLPWLVKSL 405 GL +++ L Sbjct: 88 GLASVIRPL 96 >UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family - Dinoroseobacter shibae DFL 12 Length = 321 Score = 48.8 bits (111), Expect = 3e-04 Identities = 22/60 (36%), Positives = 39/60 (65%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 V D++ GL+++A GTSLPE ++V+ + + + N IGSN F+IL LG+ +++ + Sbjct: 205 VSDAVIGLSLVAIGTSLPELATAVVAAIKRQSDVVLGNVIGSNIFNILAILGITVVIQPM 264 Score = 40.3 bits (90), Expect = 0.095 Identities = 19/59 (32%), Positives = 31/59 (52%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 + + + + GL I+ GTS PE + SV G + + N +GSN +ILL +G+ Sbjct: 29 IAERFGISKLLIGLVIVGFGTSTPELLVSVNAALDGAPEIALGNVVGSNIANILLIIGI 87 Score = 39.1 bits (87), Expect = 0.22 Identities = 19/65 (29%), Positives = 32/65 (49%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D V I ++ + G + +A +S PEL V + D+ +G V+GS +F Sbjct: 190 DLLVQGSVSIARAYGVSDAVIGLSLVAIGTSLPELATAVVAAIKRQSDVVLGNVIGSNIF 249 Query: 168 NVLAV 172 N+LA+ Sbjct: 250 NILAI 254 Score = 34.3 bits (75), Expect = 6.2 Identities = 16/56 (28%), Positives = 29/56 (51%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172 I ER I+ + G + +S+PEL ++ ++ +G VVGS + N+L + Sbjct: 29 IAERFGISKLLIGLVIVGFGTSTPELLVSVNAALDGAPEIALGNVVGSNIANILLI 84 >UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomonas neptunium ATCC 15444|Rep: Sodium/calcium exchanger - Hyphomonas neptunium (strain ATCC 15444) Length = 329 Score = 48.4 bits (110), Expect = 4e-04 Identities = 33/82 (40%), Positives = 42/82 (51%), Gaps = 8/82 (9%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL- 398 V L VPD GLTILA GTSLPE + + + G + N +GSN F+IL G+ Sbjct: 199 VARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVAGNILGSNVFNILGAGGIV 258 Query: 399 ----PWLVKSLFYPSTPENHWV 416 P+ V LF +HWV Sbjct: 259 ALFGPFEVAPLF---LQYDHWV 277 Score = 44.0 bits (99), Expect = 0.008 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 11/121 (9%) Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174 E + L + + G T +A +S PE+ F GD+ G ++GS VFN+L Sbjct: 197 EGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVAGNILGSNVFNILGAGG 256 Query: 175 CCALF-----AGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229 ALF A ++ D W + +++ L +L ++ +LL+L+Y Y Sbjct: 257 IVALFGPFEVAPLFLQYDHWVMGITAVLFAG------LVMLRVRMGRLLGVLLLLIYAAY 310 Query: 230 I 230 I Sbjct: 311 I 311 Score = 41.9 bits (94), Expect = 0.031 Identities = 25/86 (29%), Positives = 44/86 (51%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 ++L+ LLL ++ D V + + ++ +AG + +S+PE+FI+ Sbjct: 8 ISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGN 67 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALF 179 L +G +VGS + N+L V A ALF Sbjct: 68 PGLAIGNIVGSNIANLLMVAAIPALF 93 Score = 39.9 bits (89), Expect = 0.13 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 +G + V + G+ I+ GTS PE S G+ + I N +GSN ++L+ +P Sbjct: 31 LGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGNPGLAIGNIVGSNIANLLMVAAIP 90 Query: 400 WLVKSLFYP 408 +LF+P Sbjct: 91 ----ALFFP 95 >UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane protein; n=3; Pyrococcus|Rep: Na+/Ca2+ exchange integral membrane protein - Pyrococcus abyssi Length = 314 Score = 48.4 bits (110), Expect = 4e-04 Identities = 18/60 (30%), Positives = 39/60 (65%) Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +P+ + G+T+++ GTSLPE +S+ +G + + N IG++ DIL+ +G+ +++ + Sbjct: 196 IPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGIASIIRPI 255 Score = 42.3 bits (95), Expect = 0.023 Identities = 23/93 (24%), Positives = 47/93 (50%) Query: 313 SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVT 372 +I FI+ + + S + T + +T V + + L + + T+LPEA S + + Sbjct: 4 AIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISS 63 Query: 373 KQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 +G+ + + N++GS +I L LG+ ++ L Sbjct: 64 YKGNSGIALGNAVGSALANIALILGISAMITPL 96 Score = 37.9 bits (84), Expect = 0.50 Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 6/143 (4%) Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147 I+ F+ L+ GS D FV A I E ++ + + A++ PE ++ + Sbjct: 5 IVTAVFILGLILLIKGS---DIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAI 61 Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207 ++ + +G VGSA+ N+ + A+ +++D + +M +L Sbjct: 62 SSYKGNSGIALGNAVGSALANIALILGISAMI--TPLKVDEVANENSLIMLGVTLYAWLL 119 Query: 208 TLLDDKIYWHEALLLVLMYTFYI 230 +++ +I E L LVL+Y ++ Sbjct: 120 -MINGEISRIEGLTLVLIYGAFL 141 >UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 318 Score = 48.0 bits (109), Expect = 5e-04 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + I+ + G + +A +S PEL I+ V F E D+ VG V+GS ++N+LAV Sbjct: 197 LARNFGISELVVGLSVVAVGTSLPELAISTVAAFRKESDICVGNVLGSNIYNILAVLGIT 256 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY--WHEALLLVLMYTFYIL 231 A+ ++++ S+ D + LI ++ I W E + L++ Y FY++ Sbjct: 257 AII--HPLQINTSSLQFDMPVMIVFSLLLIPMIMRKFILTRW-EGVFLLVGYIFYMI 310 Score = 47.6 bits (108), Expect = 6e-04 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FI T IG LV I + + + + + GL+++A GTSLPE S + + Sbjct: 177 FIGLTTLIGGAHLLVNSAIYLARN-FGISELVVGLSVVAVGTSLPELAISTVAAFRKESD 235 Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405 + + N +GSN ++IL LG+ ++ L Sbjct: 236 ICVGNVLGSNIYNILAVLGITAIIHPL 262 Score = 45.2 bits (102), Expect = 0.003 Identities = 24/62 (38%), Positives = 36/62 (58%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403 LN+ I GLTI+A GTS PE V+ ++ + + I N IGSN ++ L LG+ ++ Sbjct: 34 LNIKPIIIGLTIIAFGTSAPELVTGIISGIRNLNDIAIGNVIGSNIANVGLVLGVTAIIL 93 Query: 404 SL 405 L Sbjct: 94 PL 95 Score = 40.3 bits (90), Expect = 0.095 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180 LNI I G T +A +S+PEL + D+ +G V+GS + NV V A+ Sbjct: 34 LNIKPIIIGLTIIAFGTSAPELVTGIISGIRNLNDIAIGNVIGSNIANVGLVLGVTAIIL 93 Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI-YWHEALLLV--LMYTFYI 230 +E++ + R+ + L L + + W LL+V ++YT YI Sbjct: 94 PLKVEMN--LLRREIPIIIGISGLLYLMCRNGILSRWEGGLLVVGIVVYTCYI 144 >UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein, expressed; n=8; Oryza sativa|Rep: Sodium/calcium exchanger protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 597 Score = 48.0 bits (109), Expect = 5e-04 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 4/103 (3%) Query: 306 PDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA 365 P H + F+M + W +V+ + ++ + V + GLT+LA G SL + Sbjct: 427 PPADHLAAWLAAGFVMSVAWAYAVATELLALLVSAAHVMGVDSAALGLTVLAWGNSLGDL 486 Query: 366 VSSVLVTKQGHGTMG----ISNSIGSNTFDILLCLGLPWLVKS 404 V+++ V +G G G ++ G FD+L+ LG+ L+ S Sbjct: 487 VANLAVASRGGGGGGAQVAVAGCYGGPVFDVLVGLGVSMLLSS 529 Score = 44.8 bits (101), Expect = 0.004 Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 9/157 (5%) Query: 82 QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141 +R G+ ++ +LA+ F LLG YF ++E + L ++ IAG T ++ + +P+ Sbjct: 114 RRVLGYAVMAAWLAVL-FYLLGDTAAVYFCSSLEGLSRLLRLSPAIAGVTLLSLGNGAPD 172 Query: 142 LFINCVGTFVT---EGD---LGVGAVVGSAVFNVLAVPACCALFAGA-VIELDWWSVTRD 194 ++ + +F + EG+ +G+ V+GSA+ AV + GA + +D RD Sbjct: 173 A-LSTIASFASGGGEGETTAVGLNGVLGSAMLVSSAVLGVIGVRLGARGVAVDRVDFYRD 231 Query: 195 CMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231 + + L ++ AL +Y Y++ Sbjct: 232 ASFLLAALAAVAVVLAAGEVTIWGALAFTSLYVVYVV 268 >UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative Na(+)/Ca(2+) antiporter - Uncultured methanogenic archaeon RC-I Length = 308 Score = 47.6 bits (108), Expect = 6e-04 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGD---TLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373 L I + IG + W++ D +P S+ GLT++A GTS+PE V + Sbjct: 5 LELIGLLVGIGLLVKGADWLVESARDLAFAAGIPASVIGLTLVAMGTSVPEFVVGIDSAL 64 Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 G G + + N IG+N ++ L +G+ +V + Sbjct: 65 SGVGQIAVGNVIGANISNLCLIIGVAAIVNRI 96 Score = 41.5 bits (93), Expect = 0.041 Identities = 20/66 (30%), Positives = 37/66 (56%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + + V + +TI+A GTS+PE V++++ +++ G + + N IGS + L LG Sbjct: 190 LANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKDEGDLVMGNCIGSVIVNTLFILGAA 249 Query: 400 WLVKSL 405 +V L Sbjct: 250 AIVSPL 255 Score = 41.1 bits (92), Expect = 0.054 Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 8/141 (5%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 + + C +L G V D V + ++ + T +A +S PE+ V + E Sbjct: 171 IGIACVILGGKVTVDSAVS----LANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKDE 226 Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 GDL +G +GS + N L + A+ V L V ++ L + + + Sbjct: 227 GDLVMGNCIGSVIVNTLFILGAAAI----VSPLPIAGVIDILILLGIIVLLLPILVTRSQ 282 Query: 214 IYWHEALLLVLMYTFYILEKI 234 I E +LLV++Y ++ K+ Sbjct: 283 IGHREGILLVVLYVIFVGYKV 303 >UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antiporter; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable sodium/calcium exchanger antiporter - Psychroflexus torquis ATCC 700755 Length = 158 Score = 47.2 bits (107), Expect = 8e-04 Identities = 36/121 (29%), Positives = 56/121 (46%), Gaps = 13/121 (10%) Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDL----GVGAVVGSAVFNVLAVPACCA 177 N+ + GAT A ASS PELFI F + + G+G GS +FN L +P+ Sbjct: 35 NLRDGVKGATINAVASSMPELFIALFFLFFLKDVVGFSGGLGTSFGSVLFNSLIIPSAAV 94 Query: 178 LFAGAVIELDWWSVT-------RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230 L G + + + SV+ RD LI + +I W E+ +L+ +Y Y+ Sbjct: 95 L--GVLSKTNKKSVSVSRKIILRDGFWLLFVEFMLIYFIQQGEISWIESSVLITIYVLYV 152 Query: 231 L 231 + Sbjct: 153 M 153 >UniRef50_A0VUH2 Cluster: Sodium/calcium exchanger membrane region; n=10; Alphaproteobacteria|Rep: Sodium/calcium exchanger membrane region - Dinoroseobacter shibae DFL 12 Length = 390 Score = 47.2 bits (107), Expect = 8e-04 Identities = 23/77 (29%), Positives = 41/77 (53%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F++ + +GS + +A + V+ + S+ G + A TS PE V+++ ++G Sbjct: 243 LQFVLLMLIMGSAGWCIAQLAQVLITRYELSSSMVGALMTAVVTSFPELVTTLAAVRRGA 302 Query: 377 GTMGISNSIGSNTFDIL 393 + + IG NTFDIL Sbjct: 303 LQLAVGGIIGGNTFDIL 319 >UniRef50_A7THZ1 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 678 Score = 47.2 bits (107), Expect = 8e-04 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 96 LYCFLLLGSVCEDYFVPAIEII-CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154 L CF+LLG V DY +P++ II + NI+S I+G T ++ +S P++ Sbjct: 40 LECFILLGLVTSDYLLPSLSIISTDVFNISSRISGITILSLGNSIPDITGTYQSMKKDAT 99 Query: 155 DLGVGAVVGSAVFNVLAVPACCAL 178 L +G ++G +F + V AL Sbjct: 100 SLAIGELLGGLLFVLTVVIGLMAL 123 Score = 45.2 bits (102), Expect = 0.003 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Query: 314 IYPLTFIMCITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV 371 + PL + C +G V+ YL+ + + D N+ I+G+TIL+ G S+P+ + Sbjct: 34 VNPLFLLECFILLGLVTSDYLLPSLSIISTDVFNISSRISGITILSLGNSIPDITGTYQS 93 Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405 K+ ++ I +G F + + +GL L +++ Sbjct: 94 MKKDATSLAIGELLGGLLFVLTVVIGLMALSRTI 127 Score = 41.5 bits (93), Expect = 0.041 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 4/116 (3%) Query: 310 HRHSIYPLTFIMCITWIGSVSYLVAWIITVVG---DTLNVPDSITGLTILAAGTSLPEAV 366 +R++ + I I + ++SY V ++ ++ + N+ I GLTI A G S+ + + Sbjct: 506 YRYNSNVVAIIEFIVSLCTISYSVKHVVRILTNWTERYNLTQEILGLTIFAWGNSVGDLI 565 Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL-FYPSTPENHWVTDLYF 421 S+V T+ G + IS G L LG+ L+ L Y + W T L F Sbjct: 566 SNVTFTQLGAIDIAISACFGGPLLCFLFGLGIDGLLILLNNYGQEDSSIWKTSLVF 621 >UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome shotgun sequence; n=6; Deuterostomia|Rep: Chromosome 12 SCAF14999, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1206 Score = 46.8 bits (106), Expect = 0.001 Identities = 23/78 (29%), Positives = 44/78 (56%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376 L F++ I + + V ++ ++G L++ +++ GLT+LA G S+ + S + + +QG+ Sbjct: 1025 LGFMVSAVLISAAASEVVSLLHMLGVVLSLSNTVLGLTLLAWGNSIGDCFSDITIARQGY 1084 Query: 377 GTMGISNSIGSNTFDILL 394 M IS G F IL+ Sbjct: 1085 PRMAISACFGGIVFSILV 1102 >UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr6 scaffold_15, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 562 Score = 46.8 bits (106), Expect = 0.001 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Query: 96 LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155 L F LLG+ +YF ++E + L ++ +IAG T ++ + +P+LF + V E + Sbjct: 129 LVLFYLLGNTAANYFCCSLEGLSRILKLSPNIAGVTLLSLGNGAPDLFASIVSFMGDETE 188 Query: 156 -LGVGAVVGSAVF-NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 +G+ +++G A F + + V + ++ S D + L++ ++ K Sbjct: 189 KVGLNSILGGAFFVSSIVVGIISISVCHSRPSIERSSFIWDVTFFLLSLACLLVIIMLGK 248 Query: 214 IYWHEALLLVLMYTFYIL 231 I A+ +Y Y+L Sbjct: 249 INLWGAISFFSLYFIYVL 266 Score = 44.8 bits (101), Expect = 0.004 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--- 375 F+M ITW + + ++ +G L + SI GLT+LA G SL + VS+V + G Sbjct: 406 FLMSITWTYIAADELISLLVSLGLILGISPSILGLTVLAWGNSLGDLVSNVTMALNGGAE 465 Query: 376 HGTMGISNSIGSNTFDILLCLGLP 399 + +S F+ L+ LGLP Sbjct: 466 GAQVALSGCYAGPIFNTLIGLGLP 489 >UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep: ENSANGP00000016911 - Anopheles gambiae str. PEST Length = 563 Score = 46.8 bits (106), Expect = 0.001 Identities = 42/127 (33%), Positives = 59/127 (46%), Gaps = 25/127 (19%) Query: 74 PSDGLTRFQR-QHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIIC-------------- 118 P D LT R G L++ F LY F+ + S+ D F+ AIE+I Sbjct: 58 PEDNLTTGDRIARG--LVYFFSLLYLFIGV-SIVSDRFMAAIEVITSKEKEVRVRKAGGE 114 Query: 119 ERLNIA----SDIAGATFMAAASSSPELF---INCVGTFVTEGDLGVGAVVGSAVFNVLA 171 E++ + +A T MA SS+PE+ I V GDLG G +VGSA +N+ Sbjct: 115 EQIVVVRVWNETVANLTLMALGSSAPEILLSIIEIVAKNFNAGDLGPGTIVGSAAYNLFV 174 Query: 172 VPACCAL 178 + A C L Sbjct: 175 IMAICVL 181 >UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces cerevisiae YDL206w; n=1; Candida glabrata|Rep: Similar to tr|Q12424 Saccharomyces cerevisiae YDL206w - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 748 Score = 46.8 bits (106), Expect = 0.001 Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 3/133 (2%) Query: 275 VWSFPGDKIS--FWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYL 332 V+SF D + +W L ++ LI A + D + +H F++ + I +L Sbjct: 539 VFSFTLDNMFNIYWLSLVSIILLFSLLIFEAPLKDYQ-KHITSCFAFVLSLGGISFTVHL 597 Query: 333 VAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDI 392 + ++T D+ N+ S+ GLTI A G S+ + VS++ + G + + GS I Sbjct: 598 ILDVLTSWADSFNLSPSVLGLTIFAWGNSIGDLVSNITFVQLGVIDVALGACFGSPLLYI 657 Query: 393 LLCLGLPWLVKSL 405 L +G+ ++ L Sbjct: 658 LFGIGIDGILVML 670 Score = 45.6 bits (103), Expect = 0.003 Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 3/92 (3%) Query: 322 CITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379 C +G ++ YL+ + + D L + D ++G+T+LA G ++P+ ++ K+ ++ Sbjct: 45 CFMMLGILTSDYLIPSLSFISRDILKISDRVSGMTLLALGNAIPDITTTYQSMKRNETSL 104 Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL-FYPST 410 + IG F + + LG+ +V ++ F PST Sbjct: 105 ALGELIGGVFFLLTVILGVVGIVSTVKFEPST 136 Score = 42.3 bits (95), Expect = 0.023 Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Query: 98 CFLLLGSVCEDYFVPAIEIIC-ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156 CF++LG + DY +P++ I + L I+ ++G T +A ++ P++ E L Sbjct: 45 CFMMLGILTSDYLIPSLSFISRDILKISDRVSGMTLLALGNAIPDITTTYQSMKRNETSL 104 Query: 157 GVGAVVGSAVF 167 +G ++G F Sbjct: 105 ALGELIGGVFF 115 >UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula marina DSM 3645|Rep: Cation antiporter - Blastopirellula marina DSM 3645 Length = 382 Score = 46.4 bits (105), Expect = 0.001 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 329 VSYLVAWIITVVGDTLNVPDSI----TGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384 V ++ A +++V D + V + G T LA TSLPE V++++ + G M I N Sbjct: 178 VIFVAARYLSIVADRVAVVTGLGGTFVGSTFLALTTSLPELVTTIVAVRMGAADMAIGNI 237 Query: 385 IGSNTFDILLCL 396 +GSN F+I + L Sbjct: 238 LGSNAFNIAILL 249 Score = 42.3 bits (95), Expect = 0.023 Identities = 24/62 (38%), Positives = 38/62 (61%), Gaps = 4/62 (6%) Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV---TEG-DLGVGAVVGSAVFN 168 A ++I E+ + S +AG +AAA+S PE IN + T G DL +G ++GS++FN Sbjct: 4 AADVIGEKSGLGSSLAGLVLLAAATSLPEFAINVNAVQLPDYTNGVDLAMGNILGSSLFN 63 Query: 169 VL 170 +L Sbjct: 64 LL 65 Score = 39.1 bits (87), Expect = 0.22 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 5/77 (6%) Query: 114 IEIICERLNIASDIAG----ATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 + I+ +R+ + + + G +TF+A +S PEL V + D+ +G ++GS FN+ Sbjct: 186 LSIVADRVAVVTGLGGTFVGSTFLALTTSLPELVTTIVAVRMGAADMAIGNILGSNAFNI 245 Query: 170 -LAVPACCALFAGAVIE 185 + +P GA+++ Sbjct: 246 AILLPVDAFYTRGALLQ 262 Score = 38.3 bits (85), Expect = 0.38 Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 6/94 (6%) Query: 339 VVGDTLNVPDSITGLTILAAGTSLPE---AVSSVLVTKQGHGT-MGISNSIGSNTFDILL 394 V+G+ + S+ GL +LAA TSLPE V++V + +G + + N +GS+ F++L+ Sbjct: 7 VIGEKSGLGSSLAGLVLLAAATSLPEFAINVNAVQLPDYTNGVDLAMGNILGSSLFNLLI 66 Query: 395 --CLGLPWLVKSLFYPSTPENHWVTDLYFIRINN 426 + L + K + S H ++ L I + + Sbjct: 67 LGIIDLAFRSKQRMFSSVSAAHALSALGSIALTS 100 >UniRef50_A1G1U8 Cluster: Sodium/calcium exchanger membrane region precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep: Sodium/calcium exchanger membrane region precursor - Stenotrophomonas maltophilia R551-3 Length = 321 Score = 46.4 bits (105), Expect = 0.001 Identities = 19/61 (31%), Positives = 40/61 (65%) Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409 + GL +A GT+LPE +++ ++GHG M +++ +GS+ ++LL +G +++ L P+ Sbjct: 207 LVGLLPVAIGTALPEVATAIAAARRGHGDMVMAHVLGSSVVNLLLVIGAMAVLQPLALPA 266 Query: 410 T 410 + Sbjct: 267 S 267 Score = 44.0 bits (99), Expect = 0.008 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 5/97 (5%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 LLL ++ D V A+ + +R + AG + +S PEL +N V + +L +G Sbjct: 13 LLLLALGGDSIVKAVSGLAQRFGASPFTAGLLLLGVTTSLPELAVNARALAVGQPELALG 72 Query: 160 AVVGSAVFNV---LAVPACCA--LFAGAVIELDWWSV 191 VGS++ N+ LAV A A L + + WWS+ Sbjct: 73 NAVGSSIVNLGLTLAVAAMAAPLLLRARLQTVLWWSL 109 >UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family; n=3; Epsilonproteobacteria|Rep: Calcium:H+/Na+ antiporter, CaCA family - Nitratiruptor sp. (strain SB155-2) Length = 308 Score = 46.0 bits (104), Expect = 0.002 Identities = 25/66 (37%), Positives = 35/66 (53%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399 + +L V + + GL ++A GTSLPE V S++ M I N IGSN + + LG Sbjct: 192 IARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMNDKADMSIGNIIGSNVANFSVVLGSA 251 Query: 400 WLVKSL 405 LV L Sbjct: 252 ALVNPL 257 Score = 44.4 bits (100), Expect = 0.006 Identities = 22/64 (34%), Positives = 35/64 (54%) Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404 ++ + + G T++A GTSLPE +S+ + + ISN IGS +I L LG+ +L Sbjct: 32 DISEFVIGATLVALGTSLPEMAASIAASYNHKSDLAISNVIGSVIINITLVLGIVFLFSK 91 Query: 405 LFYP 408 P Sbjct: 92 KVTP 95 Score = 42.7 bits (96), Expect = 0.018 Identities = 21/76 (27%), Positives = 38/76 (50%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ + E I +I+ + GAT +A +S PE+ + ++ + DL + V+GS + Sbjct: 18 DFIIKESEKIALHFDISEFVIGATLVALGTSLPEMAASIAASYNHKSDLAISNVIGSVII 77 Query: 168 NVLAVPACCALFAGAV 183 N+ V LF+ V Sbjct: 78 NITLVLGIVFLFSKKV 93 Score = 38.3 bits (85), Expect = 0.38 Identities = 20/71 (28%), Positives = 34/71 (47%) Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167 D+ V + I L ++ + G +A +S PEL ++ V + D+ +G ++GS V Sbjct: 183 DFAVESASHIARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMNDKADMSIGNIIGSNVA 242 Query: 168 NVLAVPACCAL 178 N V AL Sbjct: 243 NFSVVLGSAAL 253 >UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein B14D6.440; n=1; Neurospora crassa|Rep: Putative uncharacterized protein B14D6.440 - Neurospora crassa Length = 898 Score = 46.0 bits (104), Expect = 0.002 Identities = 22/59 (37%), Positives = 34/59 (57%) Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG 375 L F++ I WI +++ V I+ G L + ++I GLTI A G SL + V+ V V + G Sbjct: 758 LGFVISIAWISTIANEVVGILKAFGVILGISEAILGLTIFAVGNSLGDLVADVTVARLG 816 Score = 33.9 bits (74), Expect = 8.2 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213 G + VG ++G+A F V AL ++ + RD + + ++ LLD + Sbjct: 6 GSMAVGELIGAAGFITAVVAGSMALVREFKVQKR--TFVRDIVYFIVSISFTMMFLLDQE 63 Query: 214 IYWHEALLLVLMYTFYIL 231 ++ EA +V Y FY++ Sbjct: 64 LHLWEANAMVGCYIFYVI 81 >UniRef50_A1CY62 Cluster: Sodium/calcium transporter, putative; n=1; Neosartorya fischeri NRRL 181|Rep: Sodium/calcium transporter, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 316 Score = 46.0 bits (104), Expect = 0.002 Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Query: 305 IPDCRHRHSIYPLTFIMC-ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363 IP+ +Y +T ++ + + Y ++ + D+L++ ++ GLTI++ T+LP Sbjct: 143 IPERSTTSLLYHVTQLLFGLIALSLAGYFLSHSAVSIADSLHLSGTVFGLTIVSFATTLP 202 Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 E + +V+ +GH + + GSN F + LC G+ Sbjct: 203 EKLIAVVSGSRGHVNILAVTTAGSNIFLLTLCAGV 237 >UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane region; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Sodium/calcium exchanger membrane region - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 336 Score = 45.6 bits (103), Expect = 0.003 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 23/166 (13%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG----D 155 +LLG+ + FV +E + E+LN++ G+ A ++ PE I + + G D Sbjct: 14 ILLGA---EVFVNGVEWLGEKLNLSEGAVGSVLAAVGTALPETLIPVIAIVFSHGKEGHD 70 Query: 156 LGVGAVVGS-AVFNVLA--VPACCALF------AGAVIELDWWSVTRDCMMYXXXXXXLI 206 +G+GA++G+ + + LA V +F G ++ D+ S+TRD + I Sbjct: 71 IGIGAILGAPLMLSTLAMFVTGLAVVFFSRRRIKGNKVQADYSSMTRDLSFFIIVFAAAI 130 Query: 207 LTLLDDKIYWHEALL----LVLMYTFYILEKIN---PLDASQRMTP 245 +T H L+ +VL Y Y+ I+ LD+S + P Sbjct: 131 ITGTMPPYLRHWQLIIAGFMVLSYFLYVYVMISEERDLDSSYELPP 176 Score = 34.7 bits (76), Expect = 4.7 Identities = 16/48 (33%), Positives = 25/48 (52%) Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGS 387 +G+ LN+ + G + A GT+LPE + V+ HG G IG+ Sbjct: 28 LGEKLNLSEGAVGSVLAAVGTALPETLIPVIAIVFSHGKEGHDIGIGA 75 >UniRef50_Q75D63 Cluster: ABR160Cp; n=1; Eremothecium gossypii|Rep: ABR160Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 650 Score = 45.6 bits (103), Expect = 0.003 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 10/171 (5%) Query: 86 GFILLHCFLALYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFI 144 GF++L CF+LLG DY P + + +R I A +A +SSP+LF Sbjct: 26 GFVVLTVLHLSVCFVLLGVSASDYLCPIVVTLTSQRNRPHKGILAAILLAWCNSSPDLFS 85 Query: 145 NCVGTFVTE--GDLGVGAVVGSAVFNVLAVP-ACCALFAGAVIEL---DWWSVTRDCMMY 198 + + L VG V+G+ + V A + A + L + S+ D + Sbjct: 86 SLMSWNAANNAAALSVGEVLGACGVIICVVQGAIFMVMRSAWVNLSAAERHSIIVDLLFA 145 Query: 199 XXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQ 249 + L + + + ++++L+Y YI+ KI+ A QR P +++ Sbjct: 146 MLAVCIIGYVCLMNAVSVLDCVVMLLIYAAYIVSKIS---AGQRHAPPTIE 193 >UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protein; n=3; Coxiella burnetii|Rep: Sodium/calcium antiporter family protein - Coxiella burnetii Length = 322 Score = 45.2 bits (102), Expect = 0.003 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 9/125 (7%) Query: 56 LGIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIE 115 + I +++ P + E P + L ++ ++ FL L + + D V A + Sbjct: 146 MSITSLKKKVAP--LQELPQEKLQMSAKKS---VIWWFLGLALLFISSELLVDGAVGAAQ 200 Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175 + L I+ + G T + +S PE +G E D+ +G ++GS +FN LAV A Sbjct: 201 L----LGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEHDIAIGHIIGSNIFNSLAVLAM 256 Query: 176 CALFA 180 AL A Sbjct: 257 PALIA 261 Score = 45.2 bits (102), Expect = 0.003 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 2/68 (2%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L + D + GLTI+ TSLPE ++++ V K+ H + I + IGSN F+ L L +P L+ Sbjct: 202 LGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEH-DIAIGHIIGSNIFNSLAVLAMPALI 260 Query: 403 KSLFYPST 410 +PS+ Sbjct: 261 APGRFPSS 268 Score = 42.7 bits (96), Expect = 0.018 Identities = 20/59 (33%), Positives = 32/59 (54%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402 L +P + G+ ++ GTS PE + S + G + I N +GSN +I L LG+ L+ Sbjct: 36 LKIPSLVIGIILVGFGTSFPELIVSAIAAFHGKTQISIGNVVGSNIANIGLILGVVALI 94 Score = 37.9 bits (84), Expect = 0.50 Identities = 19/69 (27%), Positives = 33/69 (47%) Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169 F+ A + L I S + G + +S PEL ++ + F + + +G VVGS + N+ Sbjct: 25 FITASAALARHLKIPSLVIGIILVGFGTSFPELIVSAIAAFHGKTQISIGNVVGSNIANI 84 Query: 170 LAVPACCAL 178 + AL Sbjct: 85 GLILGVVAL 93 >UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein; n=1; Pisum sativum|Rep: Putative senescence-associated protein - Pisum sativum (Garden pea) Length = 284 Score = 45.2 bits (102), Expect = 0.003 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 6/122 (4%) Query: 59 VEIERNCTPAAILEFPSDGLTRFQ--RQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEI 116 +++ CT +++ + Q R G+++L +LA F LLG+ DYF P++E Sbjct: 112 LKVNPQCTSEGYIDYLRFFFCKCQSFRVLGYLVLGVWLAAL-FYLLGNTAADYFCPSLEH 170 Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 + E L + +AG + + +P++F + + +FV G V V+ L CC Sbjct: 171 LSELLKLPPTVAGVVLLPLGNGAPDVFAS-IASFV--GTDTVKLVLTCIAVPCLLQCCCC 227 Query: 177 AL 178 + Sbjct: 228 VV 229 >UniRef50_Q2GS93 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 401 Score = 45.2 bits (102), Expect = 0.003 Identities = 36/148 (24%), Positives = 62/148 (41%), Gaps = 2/148 (1%) Query: 94 LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153 L L L+ SVC DY V +I+ + NI+ G + ++ E CV + Sbjct: 250 LVLVVVTLIISVCADYMVDSIDALVATGNISKTFIGLILIPIVGNATEHVTACVVAVKDK 309 Query: 154 GDLGVGAVVGSAV-FNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212 DL +G +GS++ +L PA L ++ T + + + + T+ D Sbjct: 310 MDLAMGVAIGSSIQIALLVTPALVMLGWAIGQDMTLHFETFETIAFALSVLVVTYTVQDG 369 Query: 213 KIYWHEALLLVLMYTFYILE-KINPLDA 239 K + E +L+ +Y L +P DA Sbjct: 370 KSNYLEGAMLLGLYMIIALAFWASPADA 397 >UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriaceae|Rep: Cation antiporter - Halobacterium salinarium (Halobacterium halobium) Length = 318 Score = 45.2 bits (102), Expect = 0.003 Identities = 19/51 (37%), Positives = 31/51 (60%) Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 D GLT++A GTS+PE +SV+ + I N +GSN +++L +G+ Sbjct: 209 DLFIGLTVIAFGTSVPELATSVVSALRDEADFSIGNVVGSNIYNVLAVIGI 259 Score = 40.7 bits (91), Expect = 0.072 Identities = 24/79 (30%), Positives = 39/79 (49%) Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159 +LL V + V A + I + G T +A A+++PELF++ VG + +G Sbjct: 16 ILLLYVGAELLVSAASALALSHGIKAATVGVTVVAFATTAPELFVSTVGGITAGDSIALG 75 Query: 160 AVVGSAVFNVLAVPACCAL 178 +VGS + N+ V AL Sbjct: 76 NIVGSNIANIGLVLGTAAL 94 Score = 40.7 bits (91), Expect = 0.072 Identities = 21/50 (42%), Positives = 28/50 (56%) Query: 129 GATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178 G T +A +S PEL + V E D +G VVGS ++NVLAV A+ Sbjct: 213 GLTVIAFGTSVPELATSVVSALRDEADFSIGNVVGSNIYNVLAVIGIVAI 262 >UniRef50_Q31GA5 Cluster: Ca2+:cation antiporter (CaCA) family transporter precursor; n=1; Thiomicrospira crunogena XCL-2|Rep: Ca2+:cation antiporter (CaCA) family transporter precursor - Thiomicrospira crunogena (strain XCL-2) Length = 339 Score = 44.8 bits (101), Expect = 0.004 Identities = 21/76 (27%), Positives = 40/76 (52%) Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378 FI+ G +++ V+ D + D++ G + A TS PE V+++ + G T Sbjct: 192 FIILAVVTGIAGWVLMEAAKVISDQTGLSDTLVGGLLTALATSTPELVTTIAAIRYGALT 251 Query: 379 MGISNSIGSNTFDILL 394 + +SN G+N F++L+ Sbjct: 252 LAVSNIFGTNCFNMLV 267 >UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3; Borrelia burgdorferi group|Rep: Na+/Ca+ exchange protein, putative - Borrelia burgdorferi (Lyme disease spirochete) Length = 337 Score = 44.4 bits (100), Expect = 0.006 Identities = 22/55 (40%), Positives = 34/55 (61%) Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398 L VP + G+TI++ TS PE +S++ +G + +SN IGSN ++LL L L Sbjct: 44 LKVPTLLIGVTIVSFSTSAPELFTSLVAAFKGKNEIVVSNVIGSNIINMLLALPL 98 Score = 43.6 bits (98), Expect = 0.010 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380 M ++GS LV + + + NV + + G+ ++A GTS+PE V S+ + + Sbjct: 201 MYFLYLGS-KLLVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSLFAIIRKESDIA 259 Query: 381 ISNSIGSNTFDI 392 N IGSN F+I Sbjct: 260 FGNIIGSNIFNI 271 Score = 42.3 bits (95), Expect = 0.023 Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 7/150 (4%) Query: 87 FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146 F LL +++Y FL LGS A+ I N++ + G +A +S PEL ++ Sbjct: 192 FNLLSFAISMY-FLYLGSKL--LVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSL 248 Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206 E D+ G ++GS +FN+ + A + F +++ D + + M++ L+ Sbjct: 249 FAIIRKESDIAFGNIIGSNIFNIGFILASSSFFRPILLQ-DIYILDFSIMVFITLVLFLV 307 Query: 207 LTLLDDKIYWHE-ALLLVLMYTFYILEKIN 235 + ++ +L+ +L+Y Y L N Sbjct: 308 VKF--KGVFGRGISLIFLLLYFLYNLMLFN 335 Score = 38.3 bits (85), Expect = 0.38 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176 I L + + + G T ++ ++S+PELF + V F + ++ V V+GS + N+L Sbjct: 40 IATYLKVPTLLIGVTIVSFSTSAPELFTSLVAAFKGKNEIVVSNVIGSNIINMLLALPLA 99 Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215 F I+ D+ + M L+L D + Y Sbjct: 100 GFF--LKIKADFKRLKLSFMFLFLLMFLLLLLSFDFRSY 136 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.327 0.141 0.449 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 470,374,848 Number of Sequences: 1657284 Number of extensions: 19064628 Number of successful extensions: 54884 Number of sequences better than 10.0: 316 Number of HSP's better than 10.0 without gapping: 283 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 53734 Number of HSP's gapped (non-prelim): 1043 length of query: 427 length of database: 575,637,011 effective HSP length: 103 effective length of query: 324 effective length of database: 404,936,759 effective search space: 131199509916 effective search space used: 131199509916 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.7 bits) S2: 74 (33.9 bits)
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