SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000688-TA|BGIBMGA000688-PA|IPR004481|K+-dependent
Na+/Ca+ exchanger related-protein, IPR004837|Sodium/calcium exchanger
membrane region
         (427 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch...   423   e-117
UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car...   418   e-115
UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car...   295   2e-78
UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve...   278   2e-73
UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr...   268   1e-70
UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-...   268   2e-70
UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang...   263   7e-69
UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas...   255   1e-66
UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB....   215   2e-54
UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n...   214   3e-54
UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast...   210   4e-53
UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb...   207   5e-52
UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-...   205   2e-51
UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch...   202   1e-50
UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1...   195   2e-48
UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch...   194   3e-48
UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr...   194   3e-48
UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve...   194   5e-48
UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ...   186   7e-46
UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut...   169   1e-40
UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx...   169   2e-40
UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot...   167   6e-40
UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-...   166   9e-40
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N...   166   1e-39
UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve...   164   5e-39
UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha...   164   5e-39
UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch...   163   6e-39
UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh...   163   1e-38
UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto...   162   2e-38
UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor...   162   2e-38
UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass...   162   2e-38
UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N...   162   2e-38
UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang...   160   7e-38
UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M...   160   7e-38
UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch...   159   1e-37
UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr...   158   2e-37
UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve...   158   3e-37
UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s...   157   7e-37
UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:...   155   2e-36
UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang...   155   2e-36
UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|...   155   2e-36
UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch...   154   4e-36
UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;...   149   2e-34
UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang...   148   2e-34
UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr...   148   3e-34
UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ...   146   7e-34
UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure...   144   3e-33
UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve...   144   5e-33
UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang...   141   4e-32
UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger...   141   4e-32
UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci...   140   6e-32
UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste...   135   2e-30
UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependen...   130   9e-29
UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,...   128   3e-28
UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof...   126   8e-28
UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu...   121   4e-26
UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc...   112   2e-23
UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to potassium-...   107   4e-22
UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061...   104   5e-21
UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip...    83   1e-14
UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-...    83   2e-14
UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128, w...    78   5e-13
UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium d...    71   8e-11
UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal...    70   1e-10
UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ...    70   1e-10
UniRef50_UPI000023E8AF Cluster: hypothetical protein FG08070.1; ...    69   2e-10
UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve...    69   3e-10
UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep...    68   5e-10
UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ...    68   5e-10
UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen...    67   7e-10
UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;...    67   7e-10
UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob...    66   2e-09
UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus...    66   2e-09
UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re...    65   3e-09
UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole geno...    65   3e-09
UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ...    65   3e-09
UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    64   5e-09
UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ...    64   5e-09
UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6; ...    64   5e-09
UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7 pre...    64   5e-09
UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:...    64   7e-09
UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1; ...    64   7e-09
UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F...    64   9e-09
UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy...    64   9e-09
UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre...    64   9e-09
UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;...    63   1e-08
UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th...    63   1e-08
UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote...    63   2e-08
UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyce...    63   2e-08
UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2; ...    63   2e-08
UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na...    62   2e-08
UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr...    62   3e-08
UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote...    62   3e-08
UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces cap...    62   3e-08
UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ...    62   4e-08
UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    62   4e-08
UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ...    62   4e-08
UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C...    62   4e-08
UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to sodium-cal...    61   6e-08
UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    61   6e-08
UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ...    61   6e-08
UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    60   8e-08
UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve...    60   8e-08
UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella ve...    60   8e-08
UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces c...    60   8e-08
UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida albi...    60   8e-08
UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2; ...    60   8e-08
UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph...    60   1e-07
UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1; ...    60   1e-07
UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2; ...    60   1e-07
UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1; ...    60   1e-07
UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    60   1e-07
UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ...    60   1e-07
UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1; Schizosa...    60   1e-07
UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-...    59   2e-07
UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm...    59   2e-07
UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ...    59   2e-07
UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1; ...    59   2e-07
UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1; Methanobrevib...    59   2e-07
UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu...    59   3e-07
UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    59   3e-07
UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    59   3e-07
UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3; Caenorha...    59   3e-07
UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob...    58   3e-07
UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-...    58   3e-07
UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-...    58   3e-07
UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor...    58   3e-07
UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte...    58   4e-07
UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    58   4e-07
UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-...    58   4e-07
UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    58   6e-07
UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac...    58   6e-07
UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium...    58   6e-07
UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N...    58   6e-07
UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein...    57   8e-07
UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T...    57   8e-07
UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein...    57   8e-07
UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-...    57   8e-07
UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ...    57   8e-07
UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1; ...    57   8e-07
UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2; ...    57   8e-07
UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ...    57   8e-07
UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    57   1e-06
UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A...    57   1e-06
UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|...    57   1e-06
UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome s...    56   1e-06
UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep...    56   1e-06
UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob...    56   1e-06
UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr...    56   1e-06
UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ...    56   1e-06
UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein...    56   1e-06
UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Ar...    56   1e-06
UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, wh...    56   1e-06
UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    56   1e-06
UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ...    56   2e-06
UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R...    56   2e-06
UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat...    56   2e-06
UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04...    56   2e-06
UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria...    56   2e-06
UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;...    56   2e-06
UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M...    56   2e-06
UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N...    56   2e-06
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein...    55   3e-06
UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ...    55   3e-06
UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A...    55   3e-06
UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ...    55   3e-06
UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon...    55   3e-06
UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente...    55   3e-06
UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu...    55   4e-06
UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol...    55   4e-06
UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ...    55   4e-06
UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    55   4e-06
UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2; Caeno...    55   4e-06
UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|...    55   4e-06
UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P...    54   5e-06
UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;...    54   5e-06
UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-...    54   7e-06
UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa...    54   7e-06
UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2; ...    54   7e-06
UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein...    54   9e-06
UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-...    54   9e-06
UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a; ...    54   9e-06
UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ...    54   9e-06
UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependen...    53   1e-05
UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-...    53   1e-05
UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa...    53   1e-05
UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-...    53   2e-05
UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ...    53   2e-05
UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23; Cyanobacteri...    53   2e-05
UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    53   2e-05
UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger related-...    53   2e-05
UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Re...    53   2e-05
UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who...    53   2e-05
UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   2e-05
UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   2e-05
UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   2e-05
UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1; u...    52   2e-05
UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e...    52   2e-05
UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   3e-05
UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   3e-05
UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-...    52   3e-05
UniRef50_O83997 Cluster: Conserved hypothetical integral membran...    52   4e-05
UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs...    52   4e-05
UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro...    51   5e-05
UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; S...    51   5e-05
UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P...    51   5e-05
UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph...    51   5e-05
UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter therma...    51   7e-05
UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H...    51   7e-05
UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ...    50   9e-05
UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    50   9e-05
UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger related-...    50   9e-05
UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1; ...    50   9e-05
UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr...    50   9e-05
UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeb...    50   1e-04
UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol...    50   1e-04
UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    50   1e-04
UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum...    50   1e-04
UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091...    50   1e-04
UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute car...    50   2e-04
UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whol...    49   2e-04
UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-...    49   2e-04
UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-...    49   2e-04
UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1; Thermoc...    49   2e-04
UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A...    49   3e-04
UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomon...    48   4e-04
UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane pro...    48   4e-04
UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ...    48   5e-04
UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein, expre...    48   5e-04
UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ...    48   6e-04
UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip...    47   8e-04
UniRef50_A0VUH2 Cluster: Sodium/calcium exchanger membrane regio...    47   8e-04
UniRef50_A7THZ1 Cluster: Putative uncharacterized protein; n=1; ...    47   8e-04
UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome s...    47   0.001
UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno...    47   0.001
UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:...    47   0.001
UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces cere...    47   0.001
UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula...    46   0.001
UniRef50_A1G1U8 Cluster: Sodium/calcium exchanger membrane regio...    46   0.001
UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;...    46   0.002
UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein B14D6....    46   0.002
UniRef50_A1CY62 Cluster: Sodium/calcium transporter, putative; n...    46   0.002
UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane regio...    46   0.003
UniRef50_Q75D63 Cluster: ABR160Cp; n=1; Eremothecium gossypii|Re...    46   0.003
UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei...    45   0.003
UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein;...    45   0.003
UniRef50_Q2GS93 Cluster: Putative uncharacterized protein; n=1; ...    45   0.003
UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea...    45   0.003
UniRef50_Q31GA5 Cluster: Ca2+:cation antiporter (CaCA) family tr...    45   0.004
UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3...    44   0.006
UniRef50_A1SUD1 Cluster: Sodium/calcium exchanger membrane regio...    44   0.006
UniRef50_A5E210 Cluster: Putative uncharacterized protein; n=1; ...    44   0.006
UniRef50_A1Z7I2 Cluster: CG14743-PA; n=1; Drosophila melanogaste...    44   0.008
UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, wh...    44   0.008
UniRef50_A4FZ20 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; M...    44   0.008
UniRef50_UPI0000E479B4 Cluster: PREDICTED: similar to Na/Ca exch...    44   0.010
UniRef50_A5FXK2 Cluster: Sodium/calcium exchanger membrane regio...    44   0.010
UniRef50_A6TJL1 Cluster: Sodium/calcium exchanger membrane regio...    42   0.023
UniRef50_A6CEY3 Cluster: Putative cation transporter; n=1; Planc...    42   0.023
UniRef50_A6C0C7 Cluster: Putative uncharacterized protein; n=1; ...    42   0.023
UniRef50_A5UZB1 Cluster: Sodium/calcium exchanger membrane regio...    42   0.023
UniRef50_A1Z7I1 Cluster: CG14744-PA; n=2; Sophophora|Rep: CG1474...    42   0.023
UniRef50_Q9YH83 Cluster: Sodium-calcium exchanger; n=31; Coeloma...    42   0.041
UniRef50_Q1ARL7 Cluster: Sodium/calcium exchanger membrane regio...    42   0.041
UniRef50_A7HH14 Cluster: Cation antiporter; n=1; Anaeromyxobacte...    42   0.041
UniRef50_A5E209 Cluster: Putative uncharacterized protein; n=1; ...    42   0.041
UniRef50_Q67MI8 Cluster: Putative sodium/calcium exchanger prote...    41   0.054
UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrah...    41   0.054
UniRef50_Q4TEE8 Cluster: Chromosome undetermined SCAF5461, whole...    40   0.095
UniRef50_A1DFV4 Cluster: Sodium/calcium transporter, putative; n...    40   0.095
UniRef50_A6UIS8 Cluster: Sodium/calcium exchanger membrane regio...    40   0.13 
UniRef50_Q29QD0 Cluster: AT15857p; n=2; Drosophila melanogaster|...    40   0.13 
UniRef50_Q12424 Cluster: Putative cation exchanger YDL206W precu...    40   0.13 
UniRef50_A3TSR9 Cluster: Putative uncharacterized protein; n=1; ...    40   0.17 
UniRef50_A4X234 Cluster: Sodium/calcium exchanger membrane regio...    39   0.22 
UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;...    39   0.22 
UniRef50_Q9K8Y5 Cluster: Cation antiporter; n=1; Bacillus halodu...    39   0.29 
UniRef50_Q15ZQ8 Cluster: Sodium/calcium exchanger membrane regio...    39   0.29 
UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like p...    39   0.29 
UniRef50_A1Z8H3 Cluster: CG13223-PA; n=2; Sophophora|Rep: CG1322...    39   0.29 
UniRef50_A1CEE3 Cluster: Sodium/calcium transporter, putative; n...    39   0.29 
UniRef50_Q391I5 Cluster: Sodium/calcium exchanger membrane regio...    38   0.38 
UniRef50_A3X0Y4 Cluster: Putative uncharacterized protein; n=1; ...    38   0.38 
UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:...    38   0.50 
UniRef50_Q6FWK5 Cluster: Similar to sp|P47144 Saccharomyces cere...    38   0.67 
UniRef50_A7CDV0 Cluster: Sodium/calcium exchanger membrane regio...    37   0.88 
UniRef50_A0ZFP5 Cluster: Cation transporter, putative; n=1; Nodu...    37   0.88 
UniRef50_Q2QLY2 Cluster: Sodium/calcium exchanger protein, expre...    37   0.88 
UniRef50_A2XD69 Cluster: Putative uncharacterized protein; n=1; ...    37   0.88 
UniRef50_A0EBJ8 Cluster: Chromosome undetermined scaffold_88, wh...    37   0.88 
UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, wh...    37   0.88 
UniRef50_Q4SWH1 Cluster: Chromosome undetermined SCAF13621, whol...    37   1.2  
UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot...    37   1.2  
UniRef50_Q6KI24 Cluster: Ca2+/Na+ antiporter; n=1; Mycoplasma mo...    36   1.5  
UniRef50_Q0EYN3 Cluster: Ca2+:cation antiporter, CaCA family pro...    36   1.5  
UniRef50_A0QYN1 Cluster: Sodium/calcium exchanger protein; n=1; ...    36   1.5  
UniRef50_A0M0N5 Cluster: Sodium/calcium exchanger protein; n=3; ...    36   1.5  
UniRef50_UPI000155D014 Cluster: PREDICTED: similar to G protein-...    36   2.0  
UniRef50_Q6A563 Cluster: Sodium/calcium exchanger protein; n=3; ...    36   2.0  
UniRef50_Q4P3S5 Cluster: Putative uncharacterized protein; n=1; ...    36   2.0  
UniRef50_A3VNK6 Cluster: Cation antiporter; n=5; Bacteria|Rep: C...    35   3.6  
UniRef50_A1VRK4 Cluster: Sodium/calcium exchanger membrane regio...    35   3.6  
UniRef50_Q0DZ55 Cluster: Os02g0644900 protein; n=3; Oryza sativa...    35   3.6  
UniRef50_Q5A016 Cluster: Putative uncharacterized protein; n=1; ...    35   3.6  
UniRef50_Q2UMT2 Cluster: Ca2+/H+ antiporter VCX1 and related pro...    35   3.6  
UniRef50_A7TNF1 Cluster: Putative uncharacterized protein; n=1; ...    35   3.6  
UniRef50_UPI00015BD6AB Cluster: UPI00015BD6AB related cluster; n...    35   4.7  
UniRef50_Q9KXP3 Cluster: Putative integral membrane protein; n=3...    35   4.7  
UniRef50_Q47GX6 Cluster: Putative signal transduction protein; n...    35   4.7  
UniRef50_Q6CIX5 Cluster: Similarities with sgd|S0002286 Saccharo...    35   4.7  
UniRef50_A7ECE3 Cluster: Putative uncharacterized protein; n=1; ...    35   4.7  
UniRef50_A5DR29 Cluster: Putative uncharacterized protein; n=1; ...    35   4.7  
UniRef50_A4RDF2 Cluster: Putative uncharacterized protein; n=1; ...    35   4.7  
UniRef50_A0DA69 Cluster: Chromosome undetermined scaffold_43, wh...    34   6.2  
UniRef50_A5E199 Cluster: Putative uncharacterized protein; n=1; ...    34   6.2  
UniRef50_A5UZC9 Cluster: Glycosyl transferase, family 51 precurs...    34   8.2  

>UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=3; Endopterygota|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 542

 Score =  423 bits (1042), Expect = e-117
 Identities = 208/379 (54%), Positives = 257/379 (67%), Gaps = 25/379 (6%)

Query: 63  RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
           RNCTPAAI EFPSDG TR +R+HG+I +H  +A YCF LL  VC+DYFVPAIE++C++L 
Sbjct: 95  RNCTPAAIFEFPSDGFTREERKHGWITVHLLIACYCFWLLAIVCDDYFVPAIELMCKKLQ 154

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           +  DIAGATFMAAASSSPELFINCVGTF+T+GD+GVGAVVGSAVFN+LAVPA C LF G 
Sbjct: 155 VKEDIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQ 214

Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL-----EKIN-- 235
           V++L WW VTRD MMY      LI  L D K+ W+EA +LV  Y  YI      + IN  
Sbjct: 215 VVQLRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAMICNDSINRF 274

Query: 236 ------------PLDASQRMTP--RSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGD 281
                       P      + P   + QN    +G +  +     GS+ S  S   F   
Sbjct: 275 MSRTFRRKSCIRPYTEVTEIAPLLSNGQNNGASKGSQNGQNGHGCGSEASEDSFQDFELA 334

Query: 282 KISFWKK----LFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWII 337
              + ++      ++  WPI  +LWATIPDCR    +  LTF +CI WIG  SY VA++I
Sbjct: 335 STPWSRRDENTFAYICRWPITFLLWATIPDCRRYPKLRILTFFVCIFWIGITSYFVAFLI 394

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           TVVGDT+++PDS+ GLT LAAGTS+PEAVSS++VT QGHG MGISNSIGSNTFDILLCLG
Sbjct: 395 TVVGDTMDIPDSVMGLTFLAAGTSVPEAVSSIIVTNQGHGEMGISNSIGSNTFDILLCLG 454

Query: 398 LPWLVKSLFYPSTPENHWV 416
           LPWL+K+L +P+ P  +WV
Sbjct: 455 LPWLIKALAFPAIPGENWV 473


>UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Apis mellifera|Rep:
           PREDICTED: similar to solute carrier family 24, member 5
           - Apis mellifera
          Length = 439

 Score =  418 bits (1029), Expect = e-115
 Identities = 199/356 (55%), Positives = 253/356 (71%), Gaps = 9/356 (2%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NCTP AI EFPSDGLTR QRQ GFIL+H  +A+Y FLLL  VC+D+FVP+I+ IC+++N+
Sbjct: 23  NCTPPAIKEFPSDGLTREQRQLGFILIHFVIAIYMFLLLAIVCDDFFVPSIKKICDKINV 82

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           + D+AGAT MA A+SSPELFIN VGTF+TEGDLGVG +VGSAVFN+LAVPACC LFA  +
Sbjct: 83  SEDVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQI 142

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRM 243
           + L+ W VTRD + Y      LILTL D +I W+EAL+LVL Y  YIL  +   D +   
Sbjct: 143 LNLEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYIL--VMCFDRNIHQ 200

Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWA 303
             + V     ++  +         S++   ++ ++P  K    ++++W++TWPI  +L  
Sbjct: 201 FIQYVTR--TKKKYKNLSEKTPLFSNVEIVNMTNWPKSKC---ERIWWLITWPINFVLLI 255

Query: 304 TIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTS 361
           TIPDCR     S YPLTFIMCI WI S SY+V W+ITV+GDT  +PDSI GLT LAAG S
Sbjct: 256 TIPDCRRNTLKSWYPLTFIMCIIWIASTSYIVGWVITVIGDTFRIPDSIMGLTFLAAGMS 315

Query: 362 LPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
           +PEAVSSV+V  QGHG MGISNSIGSN FD+LLCLGLPW +K+  +   P NH+VT
Sbjct: 316 VPEAVSSVIVANQGHGAMGISNSIGSNVFDVLLCLGLPWFLKAALFSKEPGNHYVT 371


>UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute
           carrier family 24, member 5; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to solute carrier
           family 24, member 5 - Tribolium castaneum
          Length = 488

 Score =  295 bits (723), Expect = 2e-78
 Identities = 144/363 (39%), Positives = 224/363 (61%), Gaps = 32/363 (8%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           +FPS   T  Q + G I+L   + +YCF LL  +C++YF+P +E ICE LN++ D+A AT
Sbjct: 51  DFPSM-FTETQVEKGGIILVFCIGIYCFTLLAIICDNYFLPCVEKICEALNLSHDVAAAT 109

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FM+ A+S+PELF+N +GTF+TE D+G+G VVGS++FN L V +  +L A   ++L WW +
Sbjct: 110 FMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAASTPVQLHWWPI 169

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY---ILEKINPLDASQRMTPRSV 248
           +RD ++Y      L+    D  IYW+E L+L L+Y  Y   + + +   +   R+  R  
Sbjct: 170 SRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVRISNFVLRLIKRGN 229

Query: 249 QNGDLERGIEMTRRHDS--------------------------TGSDISTSSVWSFPGDK 282
           +  D E+G   T R  S                          T ++  + S++  P  K
Sbjct: 230 KVSDCEKGAAATPRRMSIAVVSSYGSYAEEQINKYTETKNIAETATEEESFSLFRMP--K 287

Query: 283 ISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGD 342
            S WKK F+  +WPI+ IL+ T+PD      ++P+TFI+CI WIGS SY+V+W+I ++G+
Sbjct: 288 GSIWKKAFFYYSWPIKFILFCTVPDPMRYPKLFPVTFILCIFWIGSNSYIVSWMIAIIGN 347

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
              +PD++ GLT LAAG  LPEA+S  +++++G G+MG+SNS+G+NT +ILL LG+PW +
Sbjct: 348 MFKIPDAVLGLTFLAAGGCLPEAISITIMSRRGEGSMGVSNSLGANTMNILLSLGMPWFL 407

Query: 403 KSL 405
           K++
Sbjct: 408 KTI 410


>UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 429

 Score =  278 bits (682), Expect = 2e-73
 Identities = 137/364 (37%), Positives = 219/364 (60%), Gaps = 19/364 (5%)

Query: 65  CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
           C P  I EFP D LT+ QR +G ++LH   +L+ F  L  VCED+FV ++  I   L + 
Sbjct: 1   CRPPNIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLK 60

Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
            D+AGATFMA  SS+P LFI  +  F TEGD+G+G +VGS +FN L + A CA+ +G  +
Sbjct: 61  PDVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTL 120

Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL-----EKINPL-- 237
           +L  + ++RD  +Y      L++++ D+K+YW+E L+ V++Y  YI+     +++  L  
Sbjct: 121 QLACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMYFNDQVEGLCK 180

Query: 238 DASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSF---PGDKI----SFWKKLF 290
              +++  + V+     +G++     +S   +++ S  W F   P  ++        +  
Sbjct: 181 TVKKKLKKKKVKPEGEGQGVDEDGGEESE-DELNKSEDWGFHDTPRTRLKPPEGACARAL 239

Query: 291 WVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
           WV T P  L+ + TIPDCR +     Y +TF + + W+  +SY + W++ ++G T  +P+
Sbjct: 240 WVFTLPSILVFYVTIPDCRKKTWRKFYLVTFTVAVIWMAVLSYFLVWMVAIIGYTYTIPE 299

Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF-Y 407
            + G+T LAAG+SLP+A++S++V KQG G M +SN IGSN FD +LCLG+PWL+KS F  
Sbjct: 300 CVMGMTFLAAGSSLPDAIASLVVAKQGSGDMAVSNCIGSNVFD-MLCLGIPWLIKSAFLQ 358

Query: 408 PSTP 411
           P  P
Sbjct: 359 PGKP 362


>UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo
           sapiens (Human)
          Length = 500

 Score =  268 bits (658), Expect = 1e-70
 Identities = 139/380 (36%), Positives = 219/380 (57%), Gaps = 39/380 (10%)

Query: 65  CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
           C  +   EFP    TR +R+ G I+++  + +Y F+ +  VC++YF+P++EII E L ++
Sbjct: 46  CVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLS 105

Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
            D+AG TFMAA SS+PEL    +G F+T+GD+G+  ++GSA++N+L + A C L +  V 
Sbjct: 106 QDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVS 165

Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTF-------------YIL 231
            L  W + RDC  Y      ++  + D+++YW+E  LL+L+Y               YI+
Sbjct: 166 TLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYII 225

Query: 232 EKINPLDAS-QRMTPRSVQN---GDLERGIEMTRRHDSTGSDI---------------ST 272
           +K +P  A   +   RS Q    G  + G    RR   T S I                 
Sbjct: 226 KKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSISLHGL 285

Query: 273 SSVWSFPGDKISF----WKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWI 326
           S V   P    +      K++FWVL+ PI  +L+ T PDCR +   + + +TF M   WI
Sbjct: 286 SQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWI 345

Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
            + +Y++ W++T+ G+TL +PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +G
Sbjct: 346 SAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVG 405

Query: 387 SNTFDILLCLGLPWLVKSLF 406
           SN FD +LCLG+PW +K+ F
Sbjct: 406 SNVFD-MLCLGIPWFIKTAF 424


>UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 561

 Score =  268 bits (656), Expect = 2e-70
 Identities = 130/244 (53%), Positives = 168/244 (68%), Gaps = 13/244 (5%)

Query: 4   RTRQYERKHRVATIVRVVLFFGIPIVYMV-----------AKSIASNQVIVFDEPEAFSS 52
           R R+  R+ R    +R+ L   IP +Y++           A+S+A++     D     SS
Sbjct: 22  RRRRRRRRRRRRRDIRLALVLAIPSIYLLLASLASLTGFAAQSVATSSGFTGDASFVRSS 81

Query: 53  RHLLGI--VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYF 110
           R LL +  V I+ NCTP +I EFPSDGLTR+QRQHGFI++H  +A Y F LL  VC+D+F
Sbjct: 82  RKLLALNLVPIQENCTPPSIKEFPSDGLTRYQRQHGFIVIHVIIACYAFFLLAIVCDDFF 141

Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           VP+I  IC+++ ++ D+AGATFMAAASSSPELFIN VGTFVTEGDLGVG +VGSAVFN+L
Sbjct: 142 VPSIVKICDKIGMSKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNIL 201

Query: 171 AVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           AVPACC LFA  V++LDWW ++RD + Y      LI TL D +I W+EA +LVL Y FYI
Sbjct: 202 AVPACCGLFASQVLDLDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYI 261

Query: 231 LEKI 234
           L  +
Sbjct: 262 LAMV 265



 Score =  201 bits (491), Expect = 2e-50
 Identities = 94/170 (55%), Positives = 118/170 (69%), Gaps = 7/170 (4%)

Query: 249 QNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDC 308
           QNGD    +++     S   +I   + W    D +  W++ +WV TWPI  IL  TIPDC
Sbjct: 328 QNGDCNGVMDVESLESSEELEIVNMTEWP---DNV--WERCWWVFTWPINAILLITIPDC 382

Query: 309 RHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366
           R     + YPLTFIMCI WI  +SY+V W IT++GDTL +PDS+ GLT LAAG S+PEAV
Sbjct: 383 RRPSLRNWYPLTFIMCIVWIALMSYIVGWDITIIGDTLMIPDSVMGLTFLAAGMSVPEAV 442

Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416
           SSV+VT QGHGTMGISNSIGSN FD+LLCLGLPW +K+ F+P+    H+V
Sbjct: 443 SSVIVTNQGHGTMGISNSIGSNVFDVLLCLGLPWFIKASFFPTAAGEHFV 492



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 22/57 (38%), Positives = 31/57 (54%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           I II + L I   + G TF+AA  S PE   + + T    G +G+   +GS VF+VL
Sbjct: 413 ITIIGDTLMIPDSVMGLTFLAAGMSVPEAVSSVIVTNQGHGTMGISNSIGSNVFDVL 469



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL--- 393
           I  + D + +   + G T +AA +S PE   +++ T    G +G+   +GS  F+IL   
Sbjct: 145 IVKICDKIGMSKDVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVP 204

Query: 394 LCLGL 398
            C GL
Sbjct: 205 ACCGL 209


>UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=1; Danio
           rerio|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Danio rerio
          Length = 419

 Score =  263 bits (644), Expect = 7e-69
 Identities = 134/342 (39%), Positives = 207/342 (60%), Gaps = 32/342 (9%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155
           +Y F  L  VC+DYFVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T+GD
Sbjct: 1   MYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 60

Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215
           +GVG +VGSAVFN+L +   C +F    + L  W++ RD   Y      LI+ + D+K+ 
Sbjct: 61  VGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 120

Query: 216 WHEALLLVLMYTFYIL-----EKINPLDASQRMTPRSVQNG-----DLERGIEMT----- 260
           W E+L+L+++Y  YIL      ++      ++  P ++ NG     D++ G + T     
Sbjct: 121 WWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDIDDGCDATVVLLK 180

Query: 261 --------RRHDSTGSDISTSSVWSFPG--DKISFWK-----KLFWVLTWPIRLILWATI 305
                    +  +    +S  S         K+ F+K     KL W+L WP+ ++L+ T+
Sbjct: 181 KGNNSIPRSKKGNITVHVSYESCHKVNDLFKKLLFFKSGGINKLKWLLAWPLSMLLFFTV 240

Query: 306 PDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363
           P+  +      Y ++FI    WI   SY++ W++TV+G T+ +PD I G+T LAAGTS+P
Sbjct: 241 PNSANPRWERWYMVSFISSTIWIAFFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVP 300

Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           + ++S++V +QG G M ISNSIGSN FDIL+ LGLPW +++L
Sbjct: 301 DCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTL 342


>UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila
           melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 353

 Score =  255 bits (625), Expect = 1e-66
 Identities = 124/284 (43%), Positives = 180/284 (63%), Gaps = 8/284 (2%)

Query: 126 DIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
           D+AGATF+AA++S+PELF+N VGTFVT GD+G+G +VGS+VFN+L +   C +F     +
Sbjct: 4   DVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQPT-K 62

Query: 186 LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTP 245
           LDWW VTRD   Y      L   L D  + W+EA  L+L+Y  Y+++          +  
Sbjct: 63  LDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRR 122

Query: 246 RSVQNGDLERGIE--MTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWA 303
           +  ++ + E   E  MTR  +          V + P  + +F++  +W + +P  L+L  
Sbjct: 123 KKNEHAESELLDEDPMTREEEPLKG--FRDHVCAKPKTEYNFYQWTWWAIKYPAELMLAC 180

Query: 304 TIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363
           T+P  R   SI+ L+ I  I WI  +SYL+ W +T++G  LN+PD+I GLT+LAAGTS+P
Sbjct: 181 TVPSAR---SIFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVP 237

Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           E  SS +V+K+G+G+M I N+IGSNTFDIL+CLGLPWL+K L Y
Sbjct: 238 EVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLKILIY 281


>UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG2893-PB.3 - Tribolium castaneum
          Length = 480

 Score =  215 bits (525), Expect = 2e-54
 Identities = 95/172 (55%), Positives = 128/172 (74%), Gaps = 4/172 (2%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NCTP AI +FP D  T  +RQ G +++H  ++LY F+ L  VC+ +FVPA+E IC  LN+
Sbjct: 4   NCTPPAIDDFPRDFFTEKERQDGAVVVHVVVSLYLFVALAVVCDKFFVPAVEKICHALNM 63

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG-- 181
           ++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG  
Sbjct: 64  SADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGLC 123

Query: 182 --AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
              V+ LDWW +TRDC+ Y      LI  + D+++ W+EAL LVL+YT YIL
Sbjct: 124 GVKVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYIL 175



 Score =  208 bits (508), Expect = 2e-52
 Identities = 92/145 (63%), Positives = 112/145 (77%), Gaps = 3/145 (2%)

Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331
           S+W +P  +  F  +  WV+TWPI LI   TIPDC        +PLTFIMCI WIGS+SY
Sbjct: 268 SLWKWPAGRSKF-TQFTWVITWPIHLIFLFTIPDCEKPRFKKWFPLTFIMCIIWIGSLSY 326

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           +VAW+IT++GDTL +PDS+ G+T LAAGTS+PEAVSSV+V KQGHG+MGISNSIGSNTFD
Sbjct: 327 VVAWMITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHGSMGISNSIGSNTFD 386

Query: 392 ILLCLGLPWLVKSLFYPSTPENHWV 416
           ILLCLGLPW +K+ F P+    HWV
Sbjct: 387 ILLCLGLPWFIKATFMPTIAGKHWV 411



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 96  LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           + C + +GS+   Y V   I II + L I   + G TF+AA +S PE   + +      G
Sbjct: 315 IMCIIWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHG 372

Query: 155 DLGVGAVVGSAVFNVL 170
            +G+   +GS  F++L
Sbjct: 373 SMGISNSIGSNTFDIL 388



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 19/50 (38%), Positives = 28/50 (56%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           LN+   + G T +AA TS PE   +V+ T    G +G+   +GS  F+IL
Sbjct: 61  LNMSADVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 110


>UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2;
           Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX -
           Ostreococcus tauri
          Length = 443

 Score =  214 bits (523), Expect = 3e-54
 Identities = 124/337 (36%), Positives = 189/337 (56%), Gaps = 20/337 (5%)

Query: 84  QHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF 143
           ++G  +L+    LY FL +  VC+DYFV ++E IC++L ++ D+AGATFMAA SS+PELF
Sbjct: 35  RNGGWVLYVVGILYMFLGIAIVCDDYFVSSLEKICDKLGLSEDVAGATFMAAGSSAPELF 94

Query: 144 INCVGTFVTEG--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXX 201
            + +     +   ++G+ A+VGSAVFN+L +     L AG  ++LDW  VTRDCM Y   
Sbjct: 95  SSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCAGCSLDLDWRPVTRDCMFYAMA 154

Query: 202 XXXLILTLLDDKIYWHEALLLVLMYTFYIL-EKINPL------DASQR----MTPRSVQN 250
              ++L   D +I W+E L+ VL+Y  Y+L    N +       AS+R    M P     
Sbjct: 155 VLTVLLIFYDGRITWYEGLICVLLYATYVLCMCYNDVLMRWMGGASKRPKQLMVPEPTPT 214

Query: 251 --GDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDC 308
               L R     +       ++      SF     S    L  V++ P R     +IP+C
Sbjct: 215 TVPALRRADTRRQSRRPMREEVVEDEDKSFEWPDSSLGIPLH-VISLPWRFAFHFSIPNC 273

Query: 309 --RHRHSIYPLTFIMCITWIGSVSY-LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA 365
             + R + + +TF+  I+WI  +SY +V+W    VG  + +P+ + G  ++AAGTS+P+A
Sbjct: 274 ALKQRENWFAMTFLASISWISLISYCMVSWAAR-VGCVIGIPEVVMGTLVVAAGTSIPDA 332

Query: 366 VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           + S+ V K G G M ++N++GSN FDI L LGLPWL+
Sbjct: 333 LGSIAVAKAGEGDMAVANAVGSNIFDIWLGLGLPWLI 369


>UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila
           melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster
           (Fruit fly)
          Length = 542

 Score =  210 bits (514), Expect = 4e-53
 Identities = 91/167 (54%), Positives = 123/167 (73%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NCT  AI +FP D  +  QRQ G ++LH   +LY F+ L  VC++YFVPA+E IC  LN+
Sbjct: 21  NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNM 80

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           ++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG  
Sbjct: 81  SNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMT 140

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           I LDWW +TRD + Y      LI  + D+++ W+EAL+LV +Y  Y+
Sbjct: 141 IPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYL 187



 Score =  201 bits (491), Expect = 2e-50
 Identities = 88/145 (60%), Positives = 116/145 (80%), Gaps = 3/145 (2%)

Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRH--RHSIYPLTFIMCITWIGSVSY 331
           S+ S+P DK  F  +  W++ WPI L+    IPDC+    + I+PLTFIMCI WIGS+SY
Sbjct: 329 SLLSYPKDKSCF-AQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSY 387

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           +VAW+IT++GDTL +PDS+ G+T LAAGTS+PEAVSSV+V K+GHG+MGI NSIGSNTFD
Sbjct: 388 VVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFD 447

Query: 392 ILLCLGLPWLVKSLFYPSTPENHWV 416
           ILLCLG+PWL+K++F+P  P  ++V
Sbjct: 448 ILLCLGVPWLIKAVFFPIQPGQNYV 472



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           LN+ + + G T +AA TS PE   +V+ T    G +G+   +GS  F+IL
Sbjct: 78  LNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 127



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 96  LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           + C + +GS+   Y V   I II + L I   + G TF+AA +S PE   + +      G
Sbjct: 376 IMCIVWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHG 433

Query: 155 DLGVGAVVGSAVFNVL 170
            +G+   +GS  F++L
Sbjct: 434 SMGICNSIGSNTFDIL 449


>UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae
           str. PEST
          Length = 386

 Score =  207 bits (505), Expect = 5e-52
 Identities = 113/335 (33%), Positives = 179/335 (53%), Gaps = 31/335 (9%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           + P D  T  QR  G I+LH   A+Y F+LL  VC +YF+P++E +CE L ++ D+A AT
Sbjct: 5   DLPPDLFTEEQRLQGAIVLHFLAAIYFFMLLAYVCSEYFLPSVECLCEDLKLSQDVAAAT 64

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMA A+S PE F N + T     D  +G  VG+ + ++L      A   G + ++     
Sbjct: 65  FMATATSMPEFFTNTISTLAV--DSDIG--VGTIMGSMLFNTLGVAALVGLLTKMP---- 116

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTP-RSVQN 250
             D               +DDK+   +  + +L +    + K+ P   S    P   V  
Sbjct: 117 -ED-------------GTIDDKVP-KKYNIAILGHAINGVLKLPPSSESSTSAPIEPVDP 161

Query: 251 GDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRH 310
                 +E  +        +  S +   P    + W+ + W+ TWP R +++ TIPD   
Sbjct: 162 SCSNSSVESVK-------SVKWSELTQLPEASFAGWRTIMWIFTWPYRFVVFLTIPDPLR 214

Query: 311 RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL 370
              +YPLTF+ CI WIG  +YLV W+I+V+G+T  +PD++ G+T LA G  +PEA S++ 
Sbjct: 215 FRKLYPLTFVCCIGWIGVSAYLVFWMISVIGNTFGIPDTVMGMTFLAFGGCMPEAASAIT 274

Query: 371 VTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           + ++G+G MG+SNS+G+NT  IL  LGLPW ++++
Sbjct: 275 LIRRGNGAMGVSNSLGANTLAILFSLGLPWFIRTM 309


>UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3; n=2;
           Deuterostomia|Rep: PREDICTED: similar to
           potassium-dependent Na/Ca exchanger NCKX3 -
           Strongylocentrotus purpuratus
          Length = 570

 Score =  205 bits (500), Expect = 2e-51
 Identities = 91/192 (47%), Positives = 129/192 (67%), Gaps = 4/192 (2%)

Query: 57  GIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEI 116
           G+ E+E NCTP+ I EFP D  T  QR  G  + H   A+Y F+ L  VC+DYFV ++E 
Sbjct: 68  GVHEVEMNCTPSTIEEFPGDLFTEEQRAKGAFITHAICAVYMFIALAIVCDDYFVSSLEK 127

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ICE L++  D+AGATFMAA SS+PELF + +G F+ +GD+GVG +VGSAVFN+L +   C
Sbjct: 128 ICENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLC 187

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL----E 232
            LFAG V+ L WW + RD ++Y      L+L + D  I W+EAL+++LMY  Y++    +
Sbjct: 188 GLFAGQVVHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIMCFD 247

Query: 233 KINPLDASQRMT 244
            I PL+A++ +T
Sbjct: 248 IITPLNATEDIT 259



 Score =  139 bits (336), Expect = 1e-31
 Identities = 59/120 (49%), Positives = 88/120 (73%), Gaps = 2/120 (1%)

Query: 289 LFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNV 346
           L W++T PI ++L+ TIPDCR +     Y +TF + + WI   SY++ W++  +G TL++
Sbjct: 375 LKWIVTLPICILLFFTIPDCRRKRFDRWYMVTFFISVAWIAIFSYVMVWMVAYIGHTLHI 434

Query: 347 PDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406
           PD+I G+T LAAGTS+P+A++S+LV ++G G M +SNSIGSN FDIL+ L LPW +K+ F
Sbjct: 435 PDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNVFDILIGLALPWFIKTAF 494



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 20/57 (35%), Positives = 35/57 (61%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + L++ + + G T +AAG+S PE  +SV+      G +G+   +GS  F+IL+ +GL
Sbjct: 130 ENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGL 186



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 19/57 (33%), Positives = 30/57 (52%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           +  I   L+I   I G TF+AA +S P+   + +      GD+ V   +GS VF++L
Sbjct: 425 VAYIGHTLHIPDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNVFDIL 481


>UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca
           exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Na-Ca exchanger 5 - Apis mellifera
          Length = 489

 Score =  202 bits (493), Expect = 1e-50
 Identities = 87/170 (51%), Positives = 121/170 (71%)

Query: 62  ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121
           ++ CT  +I +FP D  T  QR+HG ++LH FL LYCFLL   VC DY +PA++ IC  L
Sbjct: 23  DKKCTDRSIHDFPEDLFTYEQRRHGAVILHAFLGLYCFLLTAFVCHDYLLPAVDRICISL 82

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181
           NI++D+AGATF+A ASS PELF+N +GTF+TE DLG G VVGSAVF+  A PAC AL   
Sbjct: 83  NISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTF 142

Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
             I L+W  ++RDC+MY      L++ + D KI W+EA++L++++ FY++
Sbjct: 143 YAISLEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLI 192



 Score =  148 bits (358), Expect = 3e-34
 Identities = 66/122 (54%), Positives = 91/122 (74%), Gaps = 4/122 (3%)

Query: 287 KKLFWVLTWPIRLILWATIPDC---RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
           +K +++  WP++ +L+ TIPD    R +H  YPLTFIMCI WIG  SYLV+W+ TV+GD 
Sbjct: 294 EKCWFMFGWPLKFLLFITIPDPKIERLKHW-YPLTFIMCIIWIGISSYLVSWMTTVIGDI 352

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + +PDSI GLT LAAG ++PE  S V++ +QG G M +SN++G+N  DILLCLGLPW++K
Sbjct: 353 IGIPDSIMGLTFLAAGGNMPEVASIVILARQGDGNMAMSNTLGANILDILLCLGLPWMIK 412

Query: 404 SL 405
            L
Sbjct: 413 CL 414



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 16/49 (32%), Positives = 24/49 (48%)

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           +LN+   + G T LA  +S PE   +V+ T      +G    +GS  FD
Sbjct: 81  SLNISTDVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFD 129


>UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep:
           Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 569

 Score =  195 bits (475), Expect = 2e-48
 Identities = 89/170 (52%), Positives = 119/170 (70%)

Query: 62  ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121
           E+NCT  AI EFP D  T  QR  G +LLH F ALY FL L  VC+DYFV ++E ICE+L
Sbjct: 58  EKNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEKL 117

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181
           +++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VGSAVFN+L +   C +FAG
Sbjct: 118 HLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAG 177

Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            V+ L  ++V RD   Y      LI+ + DD+I W E+L+L++MY  YI+
Sbjct: 178 QVVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYII 227



 Score =  129 bits (311), Expect = 2e-28
 Identities = 53/115 (46%), Positives = 85/115 (73%), Gaps = 2/115 (1%)

Query: 293 LTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSI 350
           ++WPI L+L+ TIP+C  +     + L+F +   WI + SY++ W++T+VG TL +PD I
Sbjct: 375 ISWPISLLLYFTIPNCAKKRWECCFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVI 434

Query: 351 TGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 435 MGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGIQTM 489



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 19/57 (33%), Positives = 35/57 (61%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + L++ + + G T +AAG+S PE  +S++     HG +G+   +GS  F+IL  +G+
Sbjct: 115 EKLHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGV 171



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 92  CFLALYCFLLLGSVCEDYF-VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTF 150
           CF+  +    +      Y  V  + I+   L I   I G TF+AA +S P+   + +   
Sbjct: 398 CFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVAR 457

Query: 151 VTEGDLGVGAVVGSAVFNVL 170
              GD+ V   +GS VF++L
Sbjct: 458 QGLGDMAVSNTIGSNVFDIL 477


>UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 492

 Score =  194 bits (474), Expect = 3e-48
 Identities = 85/132 (64%), Positives = 109/132 (82%), Gaps = 2/132 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDC-RHRHSI-YPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           ++  W++TWPI L+   TIP+C + R+   +PLTFIMCI WIGS+SY+VAW+IT++GDTL
Sbjct: 292 RQFSWIITWPIYLLFVFTIPNCAKPRYKKWFPLTFIMCIVWIGSLSYVVAWMITIIGDTL 351

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            +PDS+ G+T LAAGTS+PEAVSSV+V KQG+G+MGISNSIGSNTFDILLCLGLPW +K+
Sbjct: 352 KIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYGSMGISNSIGSNTFDILLCLGLPWFIKA 411

Query: 405 LFYPSTPENHWV 416
            F P    +HWV
Sbjct: 412 AFSPIEKGHHWV 423



 Score =  155 bits (375), Expect = 3e-36
 Identities = 64/108 (59%), Positives = 87/108 (80%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           +++D+AGATFMAAA+S+PELF+N +GTF+TEGD+GVG +VGSAVFN+LAV ACC + AG 
Sbjct: 1   MSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGM 60

Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           V+ LDWW +TRDC+ Y      LI  + D+++ W+EAL+LVL+Y  YI
Sbjct: 61  VVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYI 108



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 96  LYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           + C + +GS+   Y V   I II + L I   + G TF+AA +S PE   + +      G
Sbjct: 327 IMCIVWIGSL--SYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYG 384

Query: 155 DLGVGAVVGSAVFNVL 170
            +G+   +GS  F++L
Sbjct: 385 SMGISNSIGSNTFDIL 400



 Score = 36.3 bits (80), Expect = 1.5
 Identities = 17/46 (36%), Positives = 26/46 (56%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           + + G T +AA TS PE   +V+ T    G +G+   +GS  F+IL
Sbjct: 3   NDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNIL 48


>UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55;
           Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo
           sapiens (Human)
          Length = 644

 Score =  194 bits (474), Expect = 3e-48
 Identities = 85/169 (50%), Positives = 119/169 (70%)

Query: 63  RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
           +NCT  A+ EFP+D  T   R+ G ++LH   A+Y F  L  VC+D+FVP++E ICERL+
Sbjct: 85  KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           ++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L +   C LFAG 
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204

Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           V+ L  W + RD + Y      LI+ + D+K+ W E+L+LVLMY  YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253



 Score =  132 bits (318), Expect = 2e-29
 Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)

Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
           W  TWP+  +L+ T+P+C        + +TF     WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509

Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 19/57 (33%), Positives = 34/57 (59%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + L++ + + G T +AAG+S PE  +SV+      G +G+   +GS  F+IL  +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 20/57 (35%), Positives = 30/57 (52%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           + II   L I   I G TF+AA +S P+   + +      GD+ V   +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554


>UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 490

 Score =  194 bits (472), Expect = 5e-48
 Identities = 85/168 (50%), Positives = 117/168 (69%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NCTP AILEFP D  T+ QRQ G ++L+  ++LY F  +  VC+DYFVP +EIIC+RL +
Sbjct: 1   NCTPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGL 60

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
            +D+AGATFMA  SS+PELF + +G F+T+GD+GVG ++GSAVFNVL V   C + AG V
Sbjct: 61  QTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTV 120

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           + L WW + RD + Y      L+L L+D+ + W EA  +V  Y+ Y+L
Sbjct: 121 LYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLL 168



 Score =  136 bits (330), Expect = 8e-31
 Identities = 61/138 (44%), Positives = 95/138 (68%), Gaps = 5/138 (3%)

Query: 269 DISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWI 326
           D++  S +S P +    W ++ WVL  PI L  + TIPD +         L+FI+CI WI
Sbjct: 276 DLTLGSPFSPPEN---VWPRICWVLGLPINLSFFLTIPDVKKPSCEKWVVLSFIICIVWI 332

Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
           G  SY++ W++TV+G T  +PDS+ GL+++A G+S+P+ +SS+ V ++G G M +S+++G
Sbjct: 333 GVTSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVG 392

Query: 387 SNTFDILLCLGLPWLVKS 404
           SN FDILLCLG+PWL+K+
Sbjct: 393 SNVFDILLCLGIPWLIKT 410



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 18/62 (29%), Positives = 34/62 (54%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + ++ D L +   + G T +A G+S PE  +SV+      G +G+   +GS  F++L  +
Sbjct: 51  LEIICDRLGLQTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVI 110

Query: 397 GL 398
           G+
Sbjct: 111 GV 112


>UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           RE34149p - Nasonia vitripennis
          Length = 542

 Score =  186 bits (454), Expect = 7e-46
 Identities = 85/166 (51%), Positives = 111/166 (66%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NC   +I +FP D  T  QRQ G IL H F  LYCFLL   VC DY +PA++ IC  L I
Sbjct: 55  NCLAHSIEDFPEDLFTLQQRQQGAILFHIFFGLYCFLLTAFVCNDYLLPALDCICADLRI 114

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           ++D+AGATF+A AS  PELF+N VGTF+TE DLGVGAVVG AVFN  A PA  ALFA   
Sbjct: 115 SADVAGATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAVFNTFATPAVGALFAAKG 174

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
           I+L W  ++RDC++Y      L+L + D  + W+E+++L+ ++  Y
Sbjct: 175 IQLQWHILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLFASY 220



 Score =  164 bits (398), Expect = 5e-39
 Identities = 79/160 (49%), Positives = 108/160 (67%), Gaps = 9/160 (5%)

Query: 254 ERGIEMTRRHDSTGSDISTSSVWSFPGDKISFW------KKLFWVL-TWPIRLILWATIP 306
           E GI+   R   T S  +T+S      D I  W       + FW L TWPI+LIL+ TIP
Sbjct: 309 EPGIKTISRASETTSAPTTTSKSCNLSDTIFMWPSKSSTSEKFWFLFTWPIKLILFVTIP 368

Query: 307 DCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364
           D R++     YP+TFIMC+ WI   SY+V+W+ TVVGDT+ +PDS+ G+T L+AG +LPE
Sbjct: 369 DSRYKRLRKFYPITFIMCVMWIAVSSYMVSWMTTVVGDTVGIPDSVMGITFLSAGGNLPE 428

Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            VS V++++QGHG M +SN+IG+NT DILLCL LPW +++
Sbjct: 429 MVSIVILSRQGHGDMAMSNTIGANTLDILLCLSLPWAIRN 468


>UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3;
           Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger -
           Tursiops truncatus (Atlantic bottle-nosed dolphin)
          Length = 1014

 Score =  169 bits (411), Expect = 1e-40
 Identities = 85/211 (40%), Positives = 126/211 (59%), Gaps = 10/211 (4%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +  +R+ G+++LH F  LY F+ L  VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 435 EYPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 494

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 495 FMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 554

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI--------LEKINPLDASQRM 243
            RD   Y      LIL  LD  I W E+LLL+L Y  Y+        LE       S+R 
Sbjct: 555 FRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELWVKKQLSRRP 614

Query: 244 TPRSVQNGDLERG--IEMTRRHDSTGSDIST 272
            P+ +  GDL +G   E     + T +++ T
Sbjct: 615 VPKVMALGDLSKGDVAEAESTGERTDNEVKT 645



 Score =  112 bits (269), Expect = 2e-23
 Identities = 52/120 (43%), Positives = 78/120 (65%), Gaps = 2/120 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K+  ++   PI   LW T+PD R   +   + +TF+  I WI   SYL+ W    VG+T+
Sbjct: 822 KQAIYLFLLPIVFPLWLTVPDVRRLEARKFFVITFLGSIMWIAMFSYLMVWWAHQVGETI 881

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPW++ S
Sbjct: 882 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWMLFS 941



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ + ++     I    Y V   + V+ D L + + + G T +AAG S PE  +S++   
Sbjct: 455 IFGMLYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGIF 513

Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397
             H  +GI   +GS  F+IL  +G
Sbjct: 514 ISHSNVGIGTIVGSAVFNILFVIG 537



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
           E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 879 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWM 938

Query: 178 LFA 180
           LF+
Sbjct: 939 LFS 941


>UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7;
           Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C
           (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) -
           Drosophila melanogaster (Fruit fly)
          Length = 888

 Score =  169 bits (410), Expect = 2e-40
 Identities = 83/194 (42%), Positives = 118/194 (60%), Gaps = 4/194 (2%)

Query: 38  SNQVIVFDEPEAFSSRHLLGIVEIER-NCTPAAILEFPSDGLTRFQRQHGFILLHCFLAL 96
           SN V   DE  A + R   GI +    N T      FP D  T+ Q ++G ++LH    +
Sbjct: 285 SNAVPGSDEDNAGNQR---GINDTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVI 341

Query: 97  YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156
           Y F+ L  VC+++FVP++++I E+L I  D+AGATFMAA  S+PELF + +G FV+  D+
Sbjct: 342 YMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDV 401

Query: 157 GVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216
           G+G +VGSAVFN+L V   CALF+  V+ L WW + RDC  Y      LI    D++I+W
Sbjct: 402 GIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFW 461

Query: 217 HEALLLVLMYTFYI 230
            EAL+L  +Y  Y+
Sbjct: 462 WEALILFTIYIGYV 475



 Score =  124 bits (300), Expect = 3e-27
 Identities = 55/128 (42%), Positives = 83/128 (64%), Gaps = 2/128 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K+L +VL  P+ + +W T+PD R       +P+TFI  I WI + SYL+ W   V GDT 
Sbjct: 699 KRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTA 758

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            +P  + GLT LAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+  
Sbjct: 759 RIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYG 818

Query: 405 LFYPSTPE 412
           + Y +  E
Sbjct: 819 IIYGAPVE 826



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 21/62 (33%), Positives = 34/62 (54%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ + L + D + G T +AAG S PE  +SV+        +GI   +GS  F+IL  +
Sbjct: 359 LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 418

Query: 397 GL 398
           G+
Sbjct: 419 GM 420



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 4/69 (5%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV---LAVP-ACCAL 178
           I  ++ G TF+AA +S P+L  + +      GD+ V + VGS +F+V   L +P     +
Sbjct: 760 IPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYGI 819

Query: 179 FAGAVIELD 187
             GA +E++
Sbjct: 820 IYGAPVEVN 828


>UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein); n=2;
           Endopterygota|Rep: PREDICTED: similar to
           Sodium/potassium/calcium exchanger
           (Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera
          Length = 658

 Score =  167 bits (405), Expect = 6e-40
 Identities = 73/158 (46%), Positives = 104/158 (65%)

Query: 73  FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132
           FP D  T  QR+ G ++LH    +Y F+ L  VC+++FVP++++I E+L IA D+AGATF
Sbjct: 112 FPQDLFTVHQRRRGAVILHVIGVVYMFVALAIVCDEFFVPSLDVIIEKLEIADDVAGATF 171

Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVT 192
           MAA  S+PELF + +G FV+  D+G+G +VGSAVFN+L V   CA+F+  V+ L WW + 
Sbjct: 172 MAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRTVLSLTWWPLF 231

Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           RDC  Y      LI    D+ I+W+EAL+L   Y  Y+
Sbjct: 232 RDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYV 269



 Score =  122 bits (295), Expect = 1e-26
 Identities = 55/123 (44%), Positives = 80/123 (65%), Gaps = 2/123 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K+L ++L  PI   LW T+PD R       + +TFI  I WI + SYL+ W   V GDT+
Sbjct: 469 KRLTYILVAPILFPLWLTLPDTRTPRGKKFFAVTFIGSIFWIAAYSYLMVWWANVAGDTV 528

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            +P  + GLT LAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+  
Sbjct: 529 RIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPVPWLLYG 588

Query: 405 LFY 407
           L Y
Sbjct: 589 LIY 591



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ + L + D + G T +AAG S PE  +S++        +GI   +GS  F+IL  +
Sbjct: 153 LDVIIEKLEIADDVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVI 212

Query: 397 GL 398
           G+
Sbjct: 213 GM 214



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 17/51 (33%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           + + I  ++ G TF+AA +S P+L  + +      GD+ V + VGS +F+V
Sbjct: 526 DTVRIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDV 576


>UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger, putative -
           Nasonia vitripennis
          Length = 692

 Score =  166 bits (404), Expect = 9e-40
 Identities = 72/166 (43%), Positives = 109/166 (65%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NC+P AI +FP   +  + R+HG +++H  +A+Y FL L  VC+DYFV +++ ICE L +
Sbjct: 155 NCSPPAIEQFPRPLMGPYARKHGGLVIHVLVAIYTFLGLAIVCDDYFVASLDRICEELKL 214

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           + D+AGATFMAA SS+PEL    +G F  + D+GV  V+GSAVFN++ V + C L +  V
Sbjct: 215 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVFNIMFVISVCGLCSSTV 274

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            +L+WW + RDC  Y      ++ T+ ++ I W EAL +++MY  Y
Sbjct: 275 SKLNWWPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMYGVY 320



 Score =  137 bits (331), Expect = 6e-31
 Identities = 57/121 (47%), Positives = 84/121 (69%), Gaps = 2/121 (1%)

Query: 286 WKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
           W    W L +PI  +   T+PDCR     + YP TF + + WI   SY++ W+IT++G T
Sbjct: 492 WGLFTWGLVYPIHYMGRLTMPDCRQEKYRNWYPFTFCISMIWISFYSYIMVWMITIIGST 551

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +PD++ GLT +AAG S+P+A+SS+ V K+G G M +SN++GSN FDIL+CLGLPW ++
Sbjct: 552 LGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGLGDMAVSNAVGSNVFDILVCLGLPWFIQ 611

Query: 404 S 404
           +
Sbjct: 612 T 612



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 331 YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390
           Y VA +  +  +    PD + G T +AAG+S PE  + V+        +G+S  IGS  F
Sbjct: 200 YFVASLDRICEELKLSPD-VAGATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVF 258

Query: 391 DILLCLGLPWLVKS 404
           +I+  + +  L  S
Sbjct: 259 NIMFVISVCGLCSS 272



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 21/57 (36%), Positives = 28/57 (49%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           I II   L I   + G TF+AA  S P+   +        GD+ V   VGS VF++L
Sbjct: 545 ITIIGSTLGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGLGDMAVSNAVGSNVFDIL 601


>UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1
           (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12;
           Euarchontoglires|Rep: Sodium/potassium/calcium exchanger
           1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens
           (Human)
          Length = 1099

 Score =  166 bits (403), Expect = 1e-39
 Identities = 72/159 (45%), Positives = 107/159 (67%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +  +R+ G+++LH F  +Y F+ L  VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   C+LF+  ++ L WW +
Sbjct: 499 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LIL  LD  I W E+LLL+L Y FY+
Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597



 Score =  115 bits (276), Expect = 3e-24
 Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 2/121 (1%)

Query: 287  KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
            K+  ++   PI   LW T+PD R + S   +  TF+  I WI   SYL+ W    VG+T+
Sbjct: 907  KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETI 966

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
             + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 967  GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1026

Query: 405  L 405
            L
Sbjct: 1027 L 1027



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 21/59 (35%), Positives = 33/59 (55%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           V+ D L + + + G T +AAG S PE  +S++     H  +GI   +GS  F+IL  +G
Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119  ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
            E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 964  ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023

Query: 178  LFA 180
            LF+
Sbjct: 1024 LFS 1026


>UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 639

 Score =  164 bits (398), Expect = 5e-39
 Identities = 72/183 (39%), Positives = 114/183 (62%)

Query: 82  QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141
           +R+HG +++H F+ LYCF+ L  +C++YF  ++E +C+RL I +D+AGATFMAA SS P 
Sbjct: 44  ERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAGSSMPT 103

Query: 142 LFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXX 201
           LFI     F+ EGD+G+G ++GS++FN+L + A C LF+G VI L  W + RD  +Y   
Sbjct: 104 LFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSCVYVVN 163

Query: 202 XXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTR 261
              L++ + D+ I+++EAL+  ++YT YIL  +                 D+ +G+EM  
Sbjct: 164 LVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFESAFETCCDINKGMEMVE 223

Query: 262 RHD 264
             D
Sbjct: 224 MED 226



 Score =  133 bits (322), Expect = 7e-30
 Identities = 54/121 (44%), Positives = 88/121 (72%), Gaps = 3/121 (2%)

Query: 284 SFWKKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVG 341
           +F K++ W+   P+ L  + T+PDCR +   + YP TF + I W+ ++SY++ W ++++G
Sbjct: 416 TFSKRIVWIFMLPVHLAFYVTMPDCRVKKWEAWYPATFALSIIWMAALSYVLVWTVSIIG 475

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401
           +T ++P+ I GLT+LAAG+S+P+ +SS++V K G G M ++N IGSN FD+ LCLGLPWL
Sbjct: 476 ETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDV-LCLGLPWL 534

Query: 402 V 402
           +
Sbjct: 535 L 535



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           L +P  + G T +AAG+S+P    ++     G G +G+   IGS+ F+IL
Sbjct: 83  LRIPTDVAGATFMAAGSSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNIL 132



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 19/59 (32%), Positives = 32/59 (54%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           + II E  +I   I G T +AA SS P++  + +      GD+ +   +GS +F+VL +
Sbjct: 471 VSIIGETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDVLCL 529


>UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium
           exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein
           CG1090); n=5; Bilateria|Rep: Probable
           sodium/potassium/calcium exchanger CG1090
           (Na(+)/K(+)/Ca(2+)- exchange protein CG1090) -
           Drosophila melanogaster (Fruit fly)
          Length = 642

 Score =  164 bits (398), Expect = 5e-39
 Identities = 69/166 (41%), Positives = 110/166 (66%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           NCTP AI +FP   + ++ RQHG ++LH  +A++ F  L  VC++YFV +++ +CE L +
Sbjct: 101 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKL 160

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           + D+AGATFMAA SS+PEL    +G F  + D+G+  V+GSAVFN++ V + CAL +G V
Sbjct: 161 SPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTV 220

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            +L+WW + RDC  Y      +++ + +D I   E+++++L Y  Y
Sbjct: 221 CQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGY 266



 Score =  140 bits (340), Expect = 5e-32
 Identities = 58/116 (50%), Positives = 83/116 (71%), Gaps = 2/116 (1%)

Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
           W + +PI  +   T+PDCR     + YP TF+M + WI   SY + W+ITV+G TL +PD
Sbjct: 449 WYVVYPIHFLCKKTMPDCRQEQYRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPD 508

Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           ++ GLT +AAG S+P+A+SS+ V K+G G M +SN+IGSN FDIL+CLGLPW +++
Sbjct: 509 TVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQT 564



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + L +   + G T +AAG+S PE  + V+        +GIS  IGS  F+I+  + +
Sbjct: 156 EELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISV 212



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 20/62 (32%), Positives = 30/62 (48%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           + V  I +I   L I   + G TF+AA  S P+   +        GD+ V   +GS VF+
Sbjct: 492 FMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFD 551

Query: 169 VL 170
           +L
Sbjct: 552 IL 553


>UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium
           exchanger; n=5; Coelomata|Rep: Potassium-dependent
           sodium-calcium exchanger - Aedes aegypti (Yellowfever
           mosquito)
          Length = 207

 Score =  163 bits (397), Expect = 6e-39
 Identities = 74/164 (45%), Positives = 106/164 (64%), Gaps = 1/164 (0%)

Query: 73  FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132
           FP D  T  QR++G ++LH    +Y F+ L  VC+++FVP++++I E+L I  D+AGATF
Sbjct: 1   FPEDLFTLEQRRNGAVVLHILGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 60

Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVT 192
           MAA  S+PELF + +G FV+  D+G+G +VGSAVFN+L V   CALF+  ++ L WW + 
Sbjct: 61  MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTLLTLTWWPLF 120

Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY-ILEKIN 235
           RDC  Y      LI    D+ I W EAL+L ++Y  Y +  K N
Sbjct: 121 RDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFN 164



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 21/62 (33%), Positives = 34/62 (54%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ + L + D + G T +AAG S PE  +SV+        +GI   +GS  F+IL  +
Sbjct: 42  LDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVI 101

Query: 397 GL 398
           G+
Sbjct: 102 GM 103


>UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF15008, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 557

 Score =  163 bits (395), Expect = 1e-38
 Identities = 69/137 (50%), Positives = 96/137 (70%)

Query: 95  ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           A+Y FL L  VC+ YFVP++E + E L+++ D+AGATFMAA SS+PELF + +G F+TEG
Sbjct: 1   AIYMFLALAVVCDVYFVPSLEKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEG 60

Query: 155 DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214
           D+GVG +VGSAVFN+L +   C +FAG  I L WW + RD + Y      LIL + D+K+
Sbjct: 61  DVGVGTIVGSAVFNILVIIGICGIFAGQPISLSWWPLFRDAVFYILSILVLILVIYDEKV 120

Query: 215 YWHEALLLVLMYTFYIL 231
            W E ++L+ MY  YI+
Sbjct: 121 MWWETIILISMYGIYII 137



 Score =  129 bits (311), Expect = 2e-28
 Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)

Query: 291 WVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
           W+L+WP+ ++L  T+P+C        Y LTF+    WI   SYL+ W++T++  TL +P+
Sbjct: 325 WLLSWPVSVLLHCTVPNCSLPQWERWYLLTFLTSTLWIALFSYLMVWMVTIISFTLGIPE 384

Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FD+LL LG PW +++L
Sbjct: 385 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVLLGLGFPWALRTL 441



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 18/59 (30%), Positives = 35/59 (59%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + + L++   + G T +AAG+S PE  +S++      G +G+   +GS  F+IL+ +G+
Sbjct: 23  LSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEGDVGVGTIVGSAVFNILVIIGI 81



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 20/57 (35%), Positives = 30/57 (52%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           + II   L I   I G TF+AA +S P+   + +      GD+ V   +GS +F+VL
Sbjct: 373 VTIISFTLGIPEVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVL 429


>UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3;
           Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus
           norvegicus (Rat)
          Length = 1153

 Score =  162 bits (393), Expect = 2e-38
 Identities = 71/159 (44%), Positives = 104/159 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +   R+ G+++LH F   Y F+ L  VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI+  LD  I W E+LLL+L Y  Y+
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564



 Score =  115 bits (277), Expect = 2e-24
 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%)

Query: 287  KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
            K+  ++   PI   LW TIPD R + +   + +TF+  I WI   SYL+ W    VG+T+
Sbjct: 961  KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 1020

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
             + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 1021 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1080

Query: 405  LFYPSTP 411
            L     P
Sbjct: 1081 LINALQP 1087



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ +T++     I    Y V   + V+ D L + + + G T +AAG S PE  +S++   
Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484

Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397
             H  +GI   +GS  F+IL  +G
Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119  ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
            E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 1018 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1077

Query: 178  LFA 180
            LF+
Sbjct: 1078 LFS 1080


>UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus
           norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus
           (Rat)
          Length = 1086

 Score =  162 bits (393), Expect = 2e-38
 Identities = 71/159 (44%), Positives = 104/159 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +   R+ G+++LH F   Y F+ L  VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI+  LD  I W E+LLL+L Y  Y+
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564



 Score =  115 bits (277), Expect = 2e-24
 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%)

Query: 287  KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
            K+  ++   PI   LW TIPD R + +   + +TF+  I WI   SYL+ W    VG+T+
Sbjct: 894  KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 953

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
             + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 954  GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1013

Query: 405  LFYPSTP 411
            L     P
Sbjct: 1014 LINALQP 1020



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ +T++     I    Y V   + V+ D L + + + G T +AAG S PE  +S++   
Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484

Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397
             H  +GI   +GS  F+IL  +G
Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119  ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
            E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 951  ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1010

Query: 178  LFA 180
            LF+
Sbjct: 1011 LFS 1013


>UniRef50_Q91WD8 Cluster: Solute carrier family 24
           (Sodium/potassium/calcium exchanger), member 1; n=2;
           Eutheria|Rep: Solute carrier family 24
           (Sodium/potassium/calcium exchanger), member 1 - Mus
           musculus (Mouse)
          Length = 1130

 Score =  162 bits (393), Expect = 2e-38
 Identities = 71/159 (44%), Positives = 104/159 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +   R+ G+++LH F  +Y F+ L  VC++YFVPA+ +I  +L I+ D+AGAT
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGAT 465

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI+  LD  I W E+LLL+L Y  Y+
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYV 564



 Score =  116 bits (280), Expect = 9e-25
 Identities = 56/127 (44%), Positives = 81/127 (63%), Gaps = 2/127 (1%)

Query: 287  KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
            K+  ++   PI   LW TIPD R + S   + +TF+  I WI   SYL+ W    VG+T+
Sbjct: 938  KQAIYLFLLPIVFPLWLTIPDVRRQESRKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 997

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
             + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 998  GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1057

Query: 405  LFYPSTP 411
            L     P
Sbjct: 1058 LINALQP 1064



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ + ++     I    Y V   + V+   L + + + G T +AAG S PE  +S++   
Sbjct: 426 IFGMMYVFVALAIVCDEYFVP-ALGVITHKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484

Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397
             H  +GI   +GS  F+IL  +G
Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119  ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
            E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 995  ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1054

Query: 178  LFA 180
            LF+
Sbjct: 1055 LFS 1057


>UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1
           (Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13;
           Fungi/Metazoa group|Rep: Sodium/potassium/calcium
           exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) -
           Rattus norvegicus (Rat)
          Length = 1181

 Score =  162 bits (393), Expect = 2e-38
 Identities = 71/159 (44%), Positives = 104/159 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +   R+ G+++LH F   Y F+ L  VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 406 EYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 465

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 466 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 525

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI+  LD  I W E+LLL+L Y  Y+
Sbjct: 526 FRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYV 564



 Score =  115 bits (277), Expect = 2e-24
 Identities = 55/127 (43%), Positives = 81/127 (63%), Gaps = 2/127 (1%)

Query: 287  KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
            K+  ++   PI   LW TIPD R + +   + +TF+  I WI   SYL+ W    VG+T+
Sbjct: 989  KQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETI 1048

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
             + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 1049 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1108

Query: 405  LFYPSTP 411
            L     P
Sbjct: 1109 LINALQP 1115



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ +T++     I    Y V   + V+ D L + + + G T +AAG S PE  +S++   
Sbjct: 426 IFGMTYVFVALAIVCDEYFVP-ALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484

Query: 374 QGHGTMGISNSIGSNTFDILLCLG 397
             H  +GI   +GS  F+IL  +G
Sbjct: 485 ISHSNVGIGTIVGSAVFNILFVIG 508



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 119  ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
            E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 1046 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1105

Query: 178  LFA 180
            LF+
Sbjct: 1106 LFS 1108


>UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=1; Takifugu
           rubripes|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Takifugu rubripes
          Length = 473

 Score =  160 bits (388), Expect = 7e-38
 Identities = 70/168 (41%), Positives = 106/168 (63%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           +C P    EFP    T  +R+ G ++++  +  Y  L +  VC+DYF+P++E+I ERL +
Sbjct: 1   DCVPPQSSEFPDGFFTVQERKDGGLVIYFLIIFYMLLAVSIVCDDYFLPSLEVISERLGL 60

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           + D+AGATFMAA SS+PEL    +G FVT+GD+GV  +VGSAV+N+L + A C L     
Sbjct: 61  SQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTVA 120

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
             L  W + RDC+ Y      +I  + D+K+YW++A  L+L+Y  YI+
Sbjct: 121 GRLTCWPLFRDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIV 168



 Score =  142 bits (343), Expect = 2e-32
 Identities = 64/141 (45%), Positives = 95/141 (67%), Gaps = 6/141 (4%)

Query: 268 SDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITW 325
           S     SV++ P   +   K++FWVL+ PI  +L+ T PDCR       + +TF M   W
Sbjct: 270 SPAEQKSVFAMPESDL---KRIFWVLSLPIITLLFLTTPDCRRSFWKKWFMVTFFMSAVW 326

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           I   +Y++ W++TVVG+TL +PD++ GLT+LAAGTS+P+ V+SV+V ++G   M +SN +
Sbjct: 327 ISGFTYILVWMVTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIV 386

Query: 386 GSNTFDILLCLGLPWLVKSLF 406
           GSN FD +LCLGLPW +K+ F
Sbjct: 387 GSNVFD-MLCLGLPWFIKTAF 406



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 18/57 (31%), Positives = 33/57 (57%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           + V+ + L +   + G T +AAG+S PE V++ L      G +G+S  +GS  +++L
Sbjct: 51  LEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLL 107



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 16/59 (27%), Positives = 32/59 (54%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           + ++ E L I   + G T +AA +S P+   + +     + D+ +  +VGS VF++L +
Sbjct: 338 VTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDMLCL 396


>UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 -
           Morone saxatilis (Striped bass)
          Length = 749

 Score =  160 bits (388), Expect = 7e-38
 Identities = 69/159 (43%), Positives = 105/159 (66%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           ++P D  +  QRQ G+++LH    +Y F+ L  VC+++FVP +E+I  +L I+ D+AGAT
Sbjct: 140 DYPEDLFSVEQRQQGWVVLHVIGMIYMFVALAIVCDEFFVPGLEVITNKLQISDDVAGAT 199

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F++  ++G+G +VGSAVFN+L V   CA+F+  ++ L WW +
Sbjct: 200 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSREMLHLTWWPL 259

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI+  LD+ I W E++LLVL Y  Y+
Sbjct: 260 FRDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYV 298



 Score =  119 bits (287), Expect = 1e-25
 Identities = 56/127 (44%), Positives = 85/127 (66%), Gaps = 2/127 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K++ ++L  PI   LW T+PD R+  S   + +TFI  I WIG  SY++ W    VG+T+
Sbjct: 557 KQVTYLLLLPIVFPLWLTLPDVRNLASRKYFVITFIGSILWIGVFSYMMVWWAHQVGETV 616

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ +
Sbjct: 617 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITIGLPVPWLIYT 676

Query: 405 LFYPSTP 411
           L +   P
Sbjct: 677 LLHNGEP 683



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 21/62 (33%), Positives = 35/62 (56%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ + L + D + G T +AAG S PE  +S++     H  +GI   +GS  F+IL  +
Sbjct: 182 LEVITNKLQISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI 241

Query: 397 GL 398
           G+
Sbjct: 242 GM 243



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 17/51 (33%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 614 ETVGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 664


>UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=1; Aedes aegypti|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 520

 Score =  159 bits (386), Expect = 1e-37
 Identities = 65/160 (40%), Positives = 104/160 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           + P D  ++ +R +G I+LH   A+Y F +L  VC +YF+P++E ICE L+++ D+A AT
Sbjct: 69  DLPPDLFSKTERLNGAIILHFLAAIYFFTILAYVCSEYFLPSVEYICEDLHLSEDVAAAT 128

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMA A+S PE F N + T V + D+G+G ++GS +FN L V A   L   + ++LDWW +
Sbjct: 129 FMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTKSHVKLDWWPL 188

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           TRD ++       L+  L D+++YW+E+L+ V++Y  Y L
Sbjct: 189 TRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFL 228



 Score =  152 bits (369), Expect = 1e-35
 Identities = 68/145 (46%), Positives = 98/145 (67%), Gaps = 2/145 (1%)

Query: 263 HDSTG-SDISTSSVWSFPGDKISFWKKLFW-VLTWPIRLILWATIPDCRHRHSIYPLTFI 320
           +DS+G SD S  S           W  +FW   TWP R+I+  TIPD R    +YPLTF 
Sbjct: 299 YDSSGESDQSDDSRMHLLKISKDSWLGVFWWFYTWPFRVIVNVTIPDPRKHRKLYPLTFF 358

Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380
           MCI WIG  +Y+V W++T++G T +VP+++ GLT LA G  +PEAVS++ V ++G+G+MG
Sbjct: 359 MCIAWIGGTAYMVFWMMTIIGSTFDVPETVMGLTFLAFGGCMPEAVSAITVIRKGNGSMG 418

Query: 381 ISNSIGSNTFDILLCLGLPWLVKSL 405
           +SNS+G+NT  IL  LGLPW ++++
Sbjct: 419 VSNSLGANTLAILFSLGLPWFIRNM 443



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 312 HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV 371
           H +  + F   + ++ S  +L +  +  + + L++ + +   T +A  TS+PE  ++ + 
Sbjct: 88  HFLAAIYFFTILAYVCSEYFLPS--VEYICEDLHLSEDVAAATFMATATSMPEFFTNTIS 145

Query: 372 TKQGHGTMGISNSIGSNTFDIL 393
           T      MG+   +GS  F+ L
Sbjct: 146 TLVVDSDMGLGTIMGSMLFNTL 167


>UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo
           sapiens (Human)
          Length = 661

 Score =  158 bits (384), Expect = 2e-37
 Identities = 71/168 (42%), Positives = 107/168 (63%)

Query: 64  NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
           N T  A  ++P D  +  +R+ G I+LH    +Y F+ L  VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170

Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           + D+AGATFMAA  S+PELF + +G F+   ++G+G +VGSAVFN+L V   CALF+  +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230

Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           + L WW + RD   Y      LI+  LD+ I W E+LLL+  Y  Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278



 Score =  127 bits (306), Expect = 6e-28
 Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)

Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
           +E  N       MTP S     VQNG+L   IE      +   +    S+ ++P +    
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468

Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
            K++ +++ +PI   LW T+PD R   S   +P+TF   ITWI   SYL+ W    VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+ 
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587

Query: 404 SLFYPSTP 411
           ++ +   P
Sbjct: 588 TVIHRFQP 595



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 22/62 (35%), Positives = 36/62 (58%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           +TV+ + L + D + G T +AAG S PE  +S++     H  +GI   +GS  F+IL  +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220

Query: 397 GL 398
           G+
Sbjct: 221 GM 222



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 17/51 (33%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576


>UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 643

 Score =  158 bits (383), Expect = 3e-37
 Identities = 72/162 (44%), Positives = 105/162 (64%), Gaps = 2/162 (1%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  T  Q+Q G ++ H     Y FL L   C+++FVP++ +I E+L +  D+AGAT
Sbjct: 92  EYPEDEFTLEQKQQGAVICHIIGMCYMFLALAIACDEFFVPSLTVIIEKLELKEDVAGAT 151

Query: 132 FMAAASSSPELFINCVGTFV-TEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWS 190
           FMAA  S+PELF + +GTF+  + ++G+G +VGSAVFNVL V   CA+F+  V+EL WW 
Sbjct: 152 FMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVLELTWWP 211

Query: 191 VTRDCMMYXXXXXXLILTLLD-DKIYWHEALLLVLMYTFYIL 231
           + RDC+ Y      LI+  L  D I W E+L+L+L Y  Y++
Sbjct: 212 LFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVI 253



 Score =  119 bits (287), Expect = 1e-25
 Identities = 55/119 (46%), Positives = 80/119 (67%), Gaps = 2/119 (1%)

Query: 288 KLFWVLTWPIRLILWATIPDCRH--RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
           ++F+V+  P+  +++ T+ D R   R  +YP+TF+M I WI   SY + W  T VG T +
Sbjct: 458 RVFYVIKAPLMFLMYYTMVDVRRPERRHLYPITFLMSIFWIAFFSYFMVWWATEVGYTFD 517

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           +P  + GLT LAAGTS+P+ ++SVLV ++G G M +S+SIGSN FDI + L LPWL  S
Sbjct: 518 IPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWLCYS 576



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVT-KQGHGTMGISNSIGSNTFDILLC 395
           +TV+ + L + + + G T +AAG S PE  +S + T       +GI   +GS  F++L  
Sbjct: 134 LTVIIEKLELKEDVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFV 193

Query: 396 LGL 398
           +G+
Sbjct: 194 IGM 196



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV---LAVPACC-- 176
           +I +++ G TF+AA +S P+L  + +      GD+ V + +GS +F++   L +P  C  
Sbjct: 517 DIPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWLCYS 576

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL-VLMYTFYIL 231
           A+  G  + +    +    +M       +++++   +  W  +  L   M+ FYI+
Sbjct: 577 AVNLGLAVNVSSRGILYSVIMLFCMLIAVVVSIAASR--WRMSKSLGACMFVFYII 630


>UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 647

 Score =  157 bits (380), Expect = 7e-37
 Identities = 69/160 (43%), Positives = 104/160 (65%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  +   R+ G+++LH    +Y F+ L  VC+++FVPA+ +I  +L I+ D+AGAT
Sbjct: 132 EYPEDLFSIKDRRRGWVVLHIIGMMYMFIALAIVCDEFFVPALGVITHKLAISDDVAGAT 191

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F+   ++G+G +VGSAVFN+L V   CALF+  V+ L WW +
Sbjct: 192 FMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREVLHLTWWPL 251

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            RD   Y      LI+  LD+ I W E+++LV  YT Y++
Sbjct: 252 FRDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVI 291



 Score =  100 bits (239), Expect = 8e-20
 Identities = 45/105 (42%), Positives = 68/105 (64%)

Query: 307 DCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366
           D +     + +TF+  I WI   SYL+ W    VG+T+ + + I GLTILAAGTS+P+ +
Sbjct: 477 DKKKSRRFFVVTFLGSILWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLI 536

Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTP 411
           +SV+V ++G G M +S+S+GSN FDI + L +PWL+ S  +   P
Sbjct: 537 TSVIVARKGMGDMAVSSSVGSNIFDITVGLPVPWLMYSAIHGLAP 581



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           V+   L + D + G T +AAG S PE  +S++     H  +GI   +GS  F+IL  +G+
Sbjct: 176 VITHKLAISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 235



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 17/51 (33%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 512 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGMGDMAVSSSVGSNIFDI 562


>UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:
           Slc24a2 protein - Mus musculus (Mouse)
          Length = 711

 Score =  155 bits (377), Expect = 2e-36
 Identities = 68/160 (42%), Positives = 103/160 (64%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           ++P D  +  +R+ G I+LH    +Y F+ L  VC+++FVP++ +I E+L I+ D+AGAT
Sbjct: 120 DYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGAT 179

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G F+   ++G+G +VGSAVFN+L V   CALF+  ++ L WW +
Sbjct: 180 FMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPL 239

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            RD   Y      LI   LD+ I W E+LLL+  Y  Y++
Sbjct: 240 FRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVV 279



 Score =  124 bits (300), Expect = 3e-27
 Identities = 70/188 (37%), Positives = 104/188 (55%), Gaps = 7/188 (3%)

Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
           +E  N       MTP S     VQNG+L   IE      +T +               + 
Sbjct: 458 IELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWPTNT 517

Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
            K+  +++ +PI   LW T+PD R   S   +P+TF   ITWI   SYL+ W    VG+T
Sbjct: 518 RKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 577

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+ 
Sbjct: 578 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 637

Query: 404 SLFYPSTP 411
           ++ +  +P
Sbjct: 638 TIIHRFSP 645



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 22/62 (35%), Positives = 36/62 (58%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           +TV+ + L + D + G T +AAG S PE  +S++     H  +GI   +GS  F+IL  +
Sbjct: 162 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 221

Query: 397 GL 398
           G+
Sbjct: 222 GM 223



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 17/51 (33%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           E + I+ +I G T +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 576 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 626


>UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger
           2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2)
           (Retinal cone Na-Ca+K exchanger) (Solute carrier family
           24 member 2).; n=1; Takifugu rubripes|Rep:
           Sodium/potassium/calcium exchanger 2 precursor
           (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone
           Na-Ca+K exchanger) (Solute carrier family 24 member 2).
           - Takifugu rubripes
          Length = 449

 Score =  155 bits (376), Expect = 2e-36
 Identities = 70/159 (44%), Positives = 105/159 (66%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           ++P+D  T  +R+ G+++LH F  LY F+ L  VC+++FVPA+ +I E+L I+ D+AGAT
Sbjct: 2   DYPTDLFTIEERRQGYVVLHMFGMLYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 61

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PELF + +G FV+  ++G+G +VGSAVFN+L V   CALF+  V+ L WW +
Sbjct: 62  FMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKEVLHLTWWPL 121

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            RD   Y      LI   LD++I   E++ L+  Y  Y+
Sbjct: 122 FRDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYV 160



 Score =  116 bits (279), Expect = 1e-24
 Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 2/127 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K++ +++  PI   LW T+PD R   S   +P+TFI  I+WI   SYL+ W    VG+T 
Sbjct: 257 KQITYLVILPIVFPLWLTLPDVRRESSERFFPITFIGSISWIAFFSYLMVWWAHQVGETF 316

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            V + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L  PWL+ +
Sbjct: 317 WVTEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLLFN 376

Query: 405 LFYPSTP 411
           +     P
Sbjct: 377 IINDFQP 383



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 23/62 (37%), Positives = 36/62 (58%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           +TV+ + L + D + G T +AAG S PE  +SV+     H  +GI   +GS  F+IL  +
Sbjct: 44  LTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVI 103

Query: 397 GL 398
           G+
Sbjct: 104 GM 105



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 15/47 (31%), Positives = 27/47 (57%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           +  +I G T +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 318 VTEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 364


>UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4;
           Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis
           elegans
          Length = 596

 Score =  155 bits (376), Expect = 2e-36
 Identities = 63/158 (39%), Positives = 106/158 (67%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           +FP D  +  QRQ+GF++LH    +Y F+ L  VC+++FVP+++++ E+L+++ D+AGAT
Sbjct: 86  QFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVLTEKLSLSDDVAGAT 145

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PE F + +G F+ + ++G+G +VGSA FN+L V A C LF+ ++++L WW +
Sbjct: 146 FMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSKSILDLTWWPL 205

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            RD  +Y      L+   +D+ I + EAL +  +Y  Y
Sbjct: 206 FRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVY 243



 Score =  127 bits (307), Expect = 5e-28
 Identities = 56/118 (47%), Positives = 81/118 (68%), Gaps = 2/118 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K+L +VL  P+ + +W TIPD R  H   +YP TFI+ I WI   SYL+ W    +G+T 
Sbjct: 395 KRLTYVLLAPVVIPMWVTIPDVRKSHNRGLYPATFIISILWIAFFSYLMVWWANTIGETF 454

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
            +P  I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FD+ + L +PWL+
Sbjct: 455 VIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLL 512



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 22/60 (36%), Positives = 34/60 (56%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ + L++ D + G T +AAG S PE  +SV+        +GI   +GS TF+IL  L
Sbjct: 128 LDVLTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVL 187



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 19/53 (35%), Positives = 30/53 (56%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           I E   I ++I G T +AA +S P+L  + +      GD+ V + VGS +F+V
Sbjct: 450 IGETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDV 502


>UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium
           exchanger, putative; n=2; Culicidae|Rep:
           Potassium-dependent sodium-calcium exchanger, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 549

 Score =  154 bits (374), Expect = 4e-36
 Identities = 65/165 (39%), Positives = 105/165 (63%), Gaps = 1/165 (0%)

Query: 68  AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127
           +AI E P D  T+ QR  G I+LH   A+Y F LL  +  +YF+P++E ICE L +  D+
Sbjct: 86  SAIDELPDDVFTQEQRLQGAIILHFIGAIYFFTLLAYIVGEYFLPSVECICEDLKLTQDV 145

Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187
           A ATFMA A + PE F N + TF+ + D+G+G ++GS +FN L V     L     ++LD
Sbjct: 146 AAATFMAIAGTIPEFFTNTISTFIADSDMGIGTIMGSLLFNTLGVACLAGLACKKPVQLD 205

Query: 188 WWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALL-LVLMYTFYIL 231
           WW +TRDC+++      L+    D +IYW+E+++ ++L++T++++
Sbjct: 206 WWPITRDCIVFAFHISVLVGFAWDGRIYWYESMVFVILLFTYFVV 250



 Score =  138 bits (333), Expect = 3e-31
 Identities = 64/178 (35%), Positives = 112/178 (62%), Gaps = 7/178 (3%)

Query: 240 SQRMTPRSVQNGDLERGIEMTRRHDSTGSD-ISTSSVWSFPGDKISFWKKLFWVLTWPIR 298
           S +M  + ++ GDL+    +  RH    ++     S+W    +  +  + ++W+ +WPIR
Sbjct: 312 SDQMAEKPMKVGDLQ----IPSRHVLPDTEEYPPMSLWKIARE--TKLRTIWWLYSWPIR 365

Query: 299 LILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAA 358
            +L  TIP+  +    YPLTFIMCI +IG  S+L  W+++++G TL +PD + GLT LA 
Sbjct: 366 FVLTFTIPNPTYMRRWYPLTFIMCIIFIGLTSFLTFWMMSIIGYTLGIPDGVMGLTFLAM 425

Query: 359 GTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416
           G  +PEA+S+VL+ + G+G +G+SN++G+N+  I+  LGLPW ++++   ++  N +V
Sbjct: 426 GGCMPEAISAVLIIRTGNGAVGVSNALGANSLSIVFSLGLPWFIRTVADGASTTNAYV 483


>UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-5 - Caenorhabditis elegans
          Length = 591

 Score =  149 bits (360), Expect = 2e-34
 Identities = 67/158 (42%), Positives = 99/158 (62%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           +FP+D  +   R+ G +++H  L +Y F+ L  VC+++FVP++ +I E L I+ D+AGAT
Sbjct: 18  QFPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVLAISDDVAGAT 77

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
           FMAA  S+PE F +  G FV + ++GVG +VGSA FN+L V A C LF+  V+ L WW +
Sbjct: 78  FMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPL 137

Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            RD   Y      L++   D+ I W EAL++  MY  Y
Sbjct: 138 FRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAY 175



 Score =  114 bits (274), Expect = 5e-24
 Identities = 53/118 (44%), Positives = 76/118 (64%), Gaps = 2/118 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHR--HSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           KKL ++   PI   L  T+PD R       + +TFI  I WI + SYL+ W    +G+T 
Sbjct: 392 KKLIYLFLAPITFPLAYTLPDVRKPSLRKFFAITFIGAILWIAAYSYLMVWWANTIGETF 451

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
            +P  I GLTILAAGTS+P+ ++SV+V ++G G M +S+SIGSN FD+ + L +PWL+
Sbjct: 452 GIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDVCVGLPIPWLI 509



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           ++V+ + L + D + G T +AAG S PE  +S+         +G+   +GS TF+IL  L
Sbjct: 60  LSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVL 119



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           I E   I ++I G T +AA +S P+L  + +      GD+ V + +GS +F+V
Sbjct: 447 IGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDV 499


>UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger
           5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
           (Solute carrier family 24 member 5). - Xenopus
           tropicalis
          Length = 555

 Score =  148 bits (359), Expect = 2e-34
 Identities = 65/136 (47%), Positives = 104/136 (76%), Gaps = 7/136 (5%)

Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331
           SV++ P + +   K++ WVL+ PI  +L+ T+PDCR +   +++ LTF+M   WI +V+Y
Sbjct: 348 SVFTMPENDL---KRIIWVLSLPIITLLYLTVPDCRRKRWKNLFILTFLMSAVWISAVTY 404

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ-GHGTMGISNSIGSNTF 390
           ++ W++TVVG+TL++PD++ GLT+LAAGTS+P+ V+SVLV ++ G G M +SN +GSN F
Sbjct: 405 ILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVF 464

Query: 391 DILLCLGLPWLVKSLF 406
           D +LCLG+PW +K++F
Sbjct: 465 D-MLCLGVPWFIKTVF 479



 Score =  129 bits (312), Expect = 1e-28
 Identities = 68/174 (39%), Positives = 100/174 (57%), Gaps = 9/174 (5%)

Query: 59  VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIIC 118
           +E E  C  +   EFP D  T  +R+ G +++H  + LY FL +  VCE YF+P++E+I 
Sbjct: 1   LENETLCIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVIS 60

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV-PACCA 177
           ERL ++ D+AGATFMA  SS+PE     +G FVT+GD+GV  +VGSAV+N+L +  ACC 
Sbjct: 61  ERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCL 120

Query: 178 LFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           L    +  L  W      M +         T+  D    +E+  L+L+Y  YI+
Sbjct: 121 LSLSLLYMLKVWRYVCPWMYFS--------TIHWDAWNRYESASLILIYGIYIV 166



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL-LC 395
           + V+ + L +   + G T +A G+S PE V+  L      G +G+S  +GS  +++L +C
Sbjct: 56  LEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGIC 115

Query: 396 LGLPWLVKSLFY 407
                L  SL Y
Sbjct: 116 AACCLLSLSLLY 127



 Score = 36.3 bits (80), Expect = 1.5
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 1/60 (1%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINC-VGTFVTEGDLGVGAVVGSAVFNVLAV 172
           + ++ E L+I   + G T +AA +S P+   +  V     +GD+ +  +VGS VF++L +
Sbjct: 410 VTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVFDMLCL 469


>UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7;
           Murinae|Rep: Sodium/potassium/calcium exchanger 5
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus
           musculus (Mouse)
          Length = 501

 Score =  148 bits (358), Expect = 3e-34
 Identities = 63/167 (37%), Positives = 103/167 (61%)

Query: 65  CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
           C  +   EFP    T+ +   G I+++  + LY  + +  VC+ YF+P++EII + L ++
Sbjct: 46  CAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLS 105

Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
            D+AGATFMAA SS+PEL    +G F+T+GD+G+  ++GSA++N+L + A C L +  V 
Sbjct: 106 QDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVS 165

Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            L  W + RDC +Y      +   + D++IYW+E   L+L+Y  Y+L
Sbjct: 166 TLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVL 212



 Score =  144 bits (349), Expect = 4e-33
 Identities = 65/135 (48%), Positives = 96/135 (71%), Gaps = 6/135 (4%)

Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSY 331
           SV+S P   +   +++FWVL+ PI  +L  T PDCR +   + + +TF M   WI + +Y
Sbjct: 295 SVFSMPEADL---RRIFWVLSLPIITLLALTTPDCRRKFWKNYFVITFFMSALWISAFTY 351

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           ++ W++TV G+TL +PD++ GLT+LAAGTS+P+ V+SVLV ++G G M ISN +GSN FD
Sbjct: 352 ILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFD 411

Query: 392 ILLCLGLPWLVKSLF 406
            +LCLGLPW +K+ F
Sbjct: 412 -MLCLGLPWFIKTAF 425



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 19/57 (33%), Positives = 34/57 (59%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           + ++ D+L +   + G T +AAG+S PE V++ L      G +GIS  +GS  +++L
Sbjct: 95  LEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLL 151



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 17/59 (28%), Positives = 32/59 (54%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           + +  E L I   + G T +AA +S P+   + +     +GD+ +  +VGS VF++L +
Sbjct: 357 VTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDMLCL 415


>UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis
           pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis
           pacifica SIR-1
          Length = 361

 Score =  147 bits (355), Expect = 7e-34
 Identities = 103/314 (32%), Positives = 153/314 (48%), Gaps = 26/314 (8%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV--TE 153
           L  F  + +V E  F+ +++ I ER+ ++S +AGAT +A  +S+PEL    V  F     
Sbjct: 11  LVAFYAMSAVVEGPFMASLDRIAERMGLSSSVAGATLLAFGTSAPELSTALVALFAEGAH 70

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
              GVG++VGSA+F +L V    A+   +   LDW  V RD + Y      LI  + DD+
Sbjct: 71  ASTGVGSIVGSAIFQILVVVGFAAVVRAST--LDWRPVIRDALFYALSIVLLIAFVHDDR 128

Query: 214 IYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTS 273
           +   EA +LV  Y  Y+            +  R V   + E  +E     D    +    
Sbjct: 129 LTLVEAAILVGSYGLYL--------GVMWIWTRRVDEPEPEPELEPEPEVDPEAPE---- 176

Query: 274 SVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLV 333
                PG     + +L   LTWPI  +L A +PD   +       F + +  IG   Y +
Sbjct: 177 -----PGP----FARLRRALTWPIDRLL-ALVPDPASQARWTLPVFALSLGLIGFSCYWL 226

Query: 334 AWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
            +    +   L VP +I  LTILA G+S+PE VSS  V +QG   M ++N++GSN FDIL
Sbjct: 227 VFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFDIL 286

Query: 394 LCLGLPWLVKSLFY 407
           + LGLP L+  L +
Sbjct: 287 VSLGLPVLLYCLLH 300



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 7/137 (5%)

Query: 101 LLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGA 160
           L+G  C  + V A E I + L +   I   T +A  SS PEL  +         D+ V  
Sbjct: 218 LIGFSCY-WLVFAAEAIAQALAVPPAIIALTILAGGSSIPELVSSATVARQGRADMAVAN 276

Query: 161 VVGSAVFNV---LAVPACC-ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216
            VGS +F++   L +P     L  G ++ L   ++T   ++       ++  L   +   
Sbjct: 277 AVGSNIFDILVSLGLPVLLYCLLHGDLVGLGGATITSSLVLLGATLAMVVGLLAAQRFRA 336

Query: 217 HEAL--LLVLMYTFYIL 231
             A   LL+  Y  Y++
Sbjct: 337 SRAFGALLISAYAAYVV 353


>UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias
           amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis
           (Starfish)
          Length = 616

 Score =  144 bits (350), Expect = 3e-33
 Identities = 84/239 (35%), Positives = 134/239 (56%), Gaps = 16/239 (6%)

Query: 2   LIRTRQYERKHRVATIVRVVLFFGI----PIVYMVAKSIASNQVIVFDEPEAFSSRHLLG 57
           ++ TR   +K     +VR+ + FGI     +++ ++   ASN      EP  +++R LLG
Sbjct: 20  IMLTRPSTKKLGTRWLVRIGILFGIFATSTLIFALSSVGASNA-----EPSMYNTRQLLG 74

Query: 58  IVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEII 117
             +       +    +  + +        F+ ++  L    F+ L  +C+D+FVP++E I
Sbjct: 75  TGDTNATVVDSCTTLYEVNHVPGL-----FVTIYIILIFVLFISLAIICDDFFVPSLEAI 129

Query: 118 CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCA 177
            ERL ++ D+AGATFMAA SS+PELFI+ +G    E D+GVG +VG+AVFN+L + A  A
Sbjct: 130 SERLELSEDVAGATFMAAGSSAPELFISIIGV-SKESDVGVGTIVGTAVFNILIIIALTA 188

Query: 178 LFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI-LEKIN 235
             AG V++LDW  + RDC+ Y       I+   D  I  +EA++L+ +Y  YI L K+N
Sbjct: 189 ALAGQVLKLDWRPLVRDCISYGISIICFIIFAWDGVIEIYEAIILLGLYVAYIVLMKLN 247



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 49/129 (37%), Positives = 77/129 (59%), Gaps = 3/129 (2%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K   +++++P       TIP+C +     +Y ++F+M I WI  +S  +  ++   G  L
Sbjct: 414 KWAMFIVSFPFMCAFTWTIPNCSNPKYKRLYLVSFLMSIVWIAGLSTAMVTLVERAGCIL 473

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           N+     GL  +A GTS+P+A+SS+LV + G G M +SN+IGSN FDI L LGLP+ ++ 
Sbjct: 474 NIDHYFMGLVFVAVGTSVPDALSSILVARDGFGDMAVSNAIGSNVFDINLGLGLPFFIRI 533

Query: 405 LFYPSTPEN 413
           L   S+P N
Sbjct: 534 LI-TSSPIN 541



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 18/63 (28%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLC 395
           +  + + L + + + G T +AAG+S PE   S++ V+K+    +G+   +G+  F+IL+ 
Sbjct: 126 LEAISERLELSEDVAGATFMAAGSSAPELFISIIGVSKE--SDVGVGTIVGTAVFNILII 183

Query: 396 LGL 398
           + L
Sbjct: 184 IAL 186


>UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 209

 Score =  144 bits (348), Expect = 5e-33
 Identities = 62/116 (53%), Positives = 89/116 (76%), Gaps = 1/116 (0%)

Query: 63  RNCTPAAILEFPSDGLTRFQRQ-HGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121
           +NC   +I +FPSD +T++QRQ  G I+ H F+A+Y F  L +VC++YFV ++E IC+ L
Sbjct: 65  KNCVNPSISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCDEYFVSSLERICDGL 124

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCA 177
           N+ SD+AGATFMAA SS+PE F + +G F+T+GD+G+G +VGSAVFN+L + A CA
Sbjct: 125 NLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAICA 180



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 21/57 (36%), Positives = 32/57 (56%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           D LN+   + G T +AAG+S PE  +SV+      G +GI   +GS  F+IL  + +
Sbjct: 122 DGLNLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAI 178


>UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger
           3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3).; n=2;
           Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
           (Solute carrier family 24 member 3). - Xenopus
           tropicalis
          Length = 524

 Score =  141 bits (341), Expect = 4e-32
 Identities = 61/112 (54%), Positives = 82/112 (73%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           EFP D  +   R+HG ++LH   A+Y F  L  VC+D+FVP++E I ERL ++ D+AGAT
Sbjct: 1   EFPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAGAT 60

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           FMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L +   C LFAG V
Sbjct: 61  FMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQV 112



 Score =  135 bits (327), Expect = 2e-30
 Identities = 56/120 (46%), Positives = 89/120 (74%), Gaps = 2/120 (1%)

Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
           K+ W++TWP+ L+L+ T+P+C        + +TF+    WI ++SY++ W++T++G TL 
Sbjct: 333 KVKWMVTWPLCLLLYFTVPNCAKPRWEKWFMVTFVSSSMWIAALSYVMVWMVTIIGFTLG 392

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +PD I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 393 IPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 452



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + + L + + + G T +AAG+S PE  +SV+      G +G+   +GS  F+IL  +G+ 
Sbjct: 46  ISERLQLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVC 105

Query: 400 WL----VKSLFYPSTP 411
            L    V+S+   S P
Sbjct: 106 GLFAGQVRSMLLVSLP 121



 Score = 36.3 bits (80), Expect = 1.5
 Identities = 20/57 (35%), Positives = 30/57 (52%)

Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           + II   L I   I G TF+AA +S P+   + +      GD+ V   +GS VF++L
Sbjct: 384 VTIIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 440


>UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+
           exchanger-like protein; n=1; Microscilla marina ATCC
           23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like
           protein - Microscilla marina ATCC 23134
          Length = 389

 Score =  141 bits (341), Expect = 4e-32
 Identities = 95/322 (29%), Positives = 153/322 (47%), Gaps = 10/322 (3%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           I L   + L  F ++  + + +F+ +++ I E + +   +AGAT +A  +S+PE+     
Sbjct: 3   IWLALVVILLAFYVMTEIVDRHFIKSLDNIAEWMKLPPSVAGATLLALGTSAPEISTALF 62

Query: 148 GTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXL 205
             F+   +   GVG +VGSA+F +L V    A+   +   L+W  V RD + Y      L
Sbjct: 63  ALFLEGANPATGVGTIVGSAIFQILVVIGFAAVVKTSY--LNWRPVMRDSIFYAFSVGLL 120

Query: 206 ILTLLDDKIYWHEALLLVLMYTFY--ILEKINPLDASQRMTPRS---VQNGDLERGIEMT 260
           IL + D+K    E +  V  Y  Y  +L         +  TP++      G      E  
Sbjct: 121 ILFVADNKFTLIEGIAFVCSYFLYLFVLFLWTKYVNEEATTPKNGFETPAGSARAEFEGA 180

Query: 261 RRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFI 320
             H  T   I           + + +K L   L +P+  ++   IPD   +       F+
Sbjct: 181 AHHLDTPRPIEAIEKDMEDETRRNPFKILQKTLGYPVEFLM-NLIPDPEEKPRWTIPVFL 239

Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380
           + +  I   SY +      +   +++P +I  LTILA G+S+PE +SS +V KQG G M 
Sbjct: 240 LSLVIIAGASYFLVVAAEALAKAMDIPPAIIALTILAGGSSIPEMISSAIVAKQGRGDMA 299

Query: 381 ISNSIGSNTFDILLCLGLPWLV 402
           I+N+IGSN FDIL+ LGLP L+
Sbjct: 300 IANAIGSNIFDILMSLGLPVLI 321


>UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium
           exchanger; n=2; Eumetazoa|Rep: Testis potassium
           dependent sodium/calcium exchanger - Strongylocentrotus
           purpuratus (Purple sea urchin)
          Length = 652

 Score =  140 bits (339), Expect = 6e-32
 Identities = 64/152 (42%), Positives = 97/152 (63%), Gaps = 2/152 (1%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           +++ +    +  F+ +  +C+D+FVP++E+I E L+++ D+AGATFMAA SS+PELF   
Sbjct: 113 WVIFYAIFVIILFIAIAIICDDFFVPSLEVISETLSLSEDVAGATFMAAGSSAPELFTAV 172

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
           +G    E D+GVG +VGSAVFN+L + A  A  AG V+ LDW  + RD   Y       I
Sbjct: 173 IGV-AFESDVGVGTIVGSAVFNILIIIALTAALAGQVLNLDWRPLARDSFFYGLSLVCFI 231

Query: 207 LTLLDDKIYWHEALLLVLMYTFY-ILEKINPL 237
           +   D +  W E+L+LV++Y  Y IL K+NP+
Sbjct: 232 VFSWDTEFTWWESLILVILYVIYLILMKVNPI 263



 Score =  101 bits (243), Expect = 3e-20
 Identities = 48/119 (40%), Positives = 77/119 (64%), Gaps = 2/119 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           K L +V+++P       TIP+C        Y  +F++ I WI ++S+ +  ++  +G  L
Sbjct: 448 KWLLFVISFPFMCAFSWTIPNCSVPRLRKWYVASFLLSIFWIAALSFGMVTLVVKIGCIL 507

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           N+ D   GL I+A GTS+P+A+SS+LV + G+G M +SN+IGSN FDI L +GLP+L++
Sbjct: 508 NISDYTMGLVIVAVGTSVPDALSSILVARDGYGDMAVSNAIGSNVFDINLGIGLPYLIR 566



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 19/62 (30%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           + V+ +TL++ + + G T +AAG+S PE  ++V +       +G+   +GS  F+IL+ +
Sbjct: 140 LEVISETLSLSEDVAGATFMAAGSSAPELFTAV-IGVAFESDVGVGTIVGSAVFNILIII 198

Query: 397 GL 398
            L
Sbjct: 199 AL 200


>UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila
           melanogaster|Rep: CG17167-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 441

 Score =  135 bits (327), Expect = 2e-30
 Identities = 59/145 (40%), Positives = 95/145 (65%), Gaps = 1/145 (0%)

Query: 268 SDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIG 327
           +D+   S++++P D  S W + +W+  +PI++ L   IP       +YPL+FIMCI  IG
Sbjct: 230 ADVVPGSIYAYPRDA-SGWMQFWWIFVFPIKVTLSLLIPHPMKYRRLYPLSFIMCILCIG 288

Query: 328 SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGS 387
             +YL+ W++T  G  ++VP  + GLT LAAG+++PEAVSS++  + G   +G+SNS+G+
Sbjct: 289 GNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGA 348

Query: 388 NTFDILLCLGLPWLVKSLFYPSTPE 412
           N+  ILL LG+PW +K+  +  T E
Sbjct: 349 NSLAILLSLGVPWFIKNCIHYGTGE 373



 Score =  113 bits (272), Expect = 8e-24
 Identities = 48/104 (46%), Positives = 70/104 (67%)

Query: 75  SDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMA 134
           +D  T  Q + G+++LH F A+Y F+LL  +C DYF+P +E ICE L+++ D+A ATFMA
Sbjct: 70  ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAAATFMA 129

Query: 135 AASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
            A+S PE F N + T + E D+G+G ++GS +FN L V    AL
Sbjct: 130 TATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173


>UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependent
           Na,Ca exchanger; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to K-dependent Na,Ca exchanger -
           Strongylocentrotus purpuratus
          Length = 259

 Score =  130 bits (313), Expect = 9e-29
 Identities = 52/127 (40%), Positives = 89/127 (70%), Gaps = 3/127 (2%)

Query: 284 SFWKKLFWVLTWPIRLILWATIPDCRHR---HSIYPLTFIMCITWIGSVSYLVAWIITVV 340
           S++ ++ W +  P+ LI++ T+PDCR       +Y  TF +   W+  ++Y++ W+I V+
Sbjct: 57  SWFFRVLWFVGLPVILIMFLTVPDCRKPGLWRRLYFFTFFISTVWLAGLAYVLYWMIVVI 116

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
           G TL++PD++ G+++LAAGTS+P+A++SVLV + G+G M +SN +GSN F++ +CLGL W
Sbjct: 117 GYTLDIPDTVMGISLLAAGTSVPDAIASVLVARDGYGDMALSNIVGSNIFEVFICLGLLW 176

Query: 401 LVKSLFY 407
            +  L Y
Sbjct: 177 FIYGLVY 183


>UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 346

 Score =  128 bits (309), Expect = 3e-28
 Identities = 63/165 (38%), Positives = 103/165 (62%), Gaps = 8/165 (4%)

Query: 246 RSVQNGDLERGIEMTRRHDSTGSDISTS---SVWSFPGDKISFWKKLFWVLTWPIRLILW 302
           RS  + DLER       +D+   D + +   S +  P   ++ + ++   L +PI  + +
Sbjct: 108 RSDPHRDLERNDRRNTDNDNFVDDENETEPGSPFRLPEKGVNRYAQM---LAFPIIAVFF 164

Query: 303 ATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360
            +IPDCR +     Y LTFI  + WIG ++Y++ W++T  GDT+ +PD++ GLT+LAAG 
Sbjct: 165 ISIPDCRRKRWKRCYVLTFICSLLWIGFLTYILVWMVTAFGDTIGIPDTVMGLTLLAAGA 224

Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           S P+ + S++  + G+G M IS+SIGSN FDIL+ LGLPW ++++
Sbjct: 225 STPDTMLSIIAARGGYGDMAISHSIGSNLFDILVGLGLPWFIQTV 269



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 92  CF-LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTF 150
           C+ L   C LL         V  +    + + I   + G T +AA +S+P+  ++ +   
Sbjct: 178 CYVLTFICSLLWIGFLTYILVWMVTAFGDTIGIPDTVMGLTLLAAGASTPDTMLSIIAAR 237

Query: 151 VTEGDLGVGAVVGSAVFNVL 170
              GD+ +   +GS +F++L
Sbjct: 238 GGYGDMAISHSIGSNLFDIL 257


>UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform
           1; n=2; Ostreococcus|Rep: Solute carrier family 24
           member 4, isoform 1 - Ostreococcus tauri
          Length = 545

 Score =  126 bits (305), Expect = 8e-28
 Identities = 60/154 (38%), Positives = 90/154 (58%), Gaps = 2/154 (1%)

Query: 79  TRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASS 138
           T    + G ++ +    +Y F+ +  VC+D+FV ++E ICERL ++ D+AGATFMAA SS
Sbjct: 57  TESWEKKGGLVAYFVGVVYLFIGIAIVCDDFFVASLEKICERLGLSDDVAGATFMAAGSS 116

Query: 139 SPELFINCVGTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCM 196
           +PEL  + +    +  D  +GVG +VGSAVFN+L +     +FAG  ++LDW  + RDC 
Sbjct: 117 APELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFAGETLKLDWRPLARDCT 176

Query: 197 MYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            Y      + LT     + W E L+ V +Y  YI
Sbjct: 177 FYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYI 210



 Score =  102 bits (245), Expect = 2e-20
 Identities = 50/119 (42%), Positives = 76/119 (63%), Gaps = 5/119 (4%)

Query: 286 WKKL-FWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVS-YLVAWIITVVG 341
           WKK   WVL+ P   +L  T+P C  +   + Y ++F + + +IG +S Y+V W   + G
Sbjct: 352 WKKRPMWVLSLPWYTVLTFTVPPCHRKEWENWYIVSFCVSVAYIGVISHYMVEWCARI-G 410

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
             L++P  + G T+LAAGTS+P+A+SS+ V + G   M ++N++GSN FDI L LGLPW
Sbjct: 411 CILSIPPVVMGTTVLAAGTSIPDALSSISVARDGFADMAVANAVGSNVFDIWLGLGLPW 469



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSV--LVTKQGHGTMGISNSIGSNTFDILLCLG 397
           + L + D + G T +AAG+S PE  +S   L+       +G+   +GS  F+IL+ +G
Sbjct: 97  ERLGLSDDVAGATFMAAGSSAPELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIG 154


>UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone
           sodium-calcium potassium exchanger; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           cone sodium-calcium potassium exchanger -
           Strongylocentrotus purpuratus
          Length = 651

 Score =  121 bits (291), Expect = 4e-26
 Identities = 56/123 (45%), Positives = 85/123 (69%), Gaps = 3/123 (2%)

Query: 286 WKK-LFWVLTWPIRLILWATIPDCRHRHSI--YPLTFIMCITWIGSVSYLVAWIITVVGD 342
           W+K + ++L  P+  +L+ T+PD R   S   Y +TFI CI WI   SYL+ W+   VGD
Sbjct: 457 WRKQVTYILLAPLVYVLYFTLPDVRRVESRKWYSVTFIGCIFWIAGFSYLMVWMAKEVGD 516

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           T+ + + + GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPW++
Sbjct: 517 TIGIEERVMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWIL 576

Query: 403 KSL 405
            S+
Sbjct: 577 WSI 579



 Score =  113 bits (272), Expect = 8e-24
 Identities = 48/98 (48%), Positives = 71/98 (72%)

Query: 73  FPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATF 132
           +P D  T  Q++ G I+LH  L +Y F+ L  VC+++FVPA+ +I ++L+++ D+AGATF
Sbjct: 107 YPRDLFTLQQKKDGAIVLHVILMIYMFVALAIVCDEFFVPALSVITDKLDLSDDVAGATF 166

Query: 133 MAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           MAA  S+PELF + +G F    D+GVG +VGSAVFN+L
Sbjct: 167 MAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 19/57 (33%), Positives = 33/57 (57%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           ++V+ D L++ D + G T +AAG S PE  +S++        +G+   +GS  F+IL
Sbjct: 148 LSVITDKLDLSDDVAGATFMAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFNIL 204



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
           + + I   + G T +AA +S P+L  + +      GD+ V + VGS +F++ + +P    
Sbjct: 516 DTIGIEERVMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWI 575

Query: 178 LFA----GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL-VLMYTFYI 230
           L++    GA + +D  S    C ++      +++ +L     W    ++   M+ FY+
Sbjct: 576 LWSISQNGASVSVD--SKGLFCSIFLLFGMLILVVILIAVNKWRMTKIMGGCMFLFYL 631


>UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep:
           Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 231

 Score =  112 bits (269), Expect = 2e-23
 Identities = 47/96 (48%), Positives = 70/96 (72%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
           E+P D  T  QR+ G ++LH F  +Y F+ L  VC+++FVPA+ +I E+L I+ D+AGAT
Sbjct: 116 EYPEDLFTLEQRRQGAVVLHMFGMMYMFIALAIVCDEFFVPALTVITEKLEISDDVAGAT 175

Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           FMAA  S+PELF + +G F++  ++G+G +VGSAVF
Sbjct: 176 FMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 20/54 (37%), Positives = 30/54 (55%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390
           +TV+ + L + D + G T +AAG S PE  +SV+     H  +GI   +GS  F
Sbjct: 158 LTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211


>UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger - Nasonia
           vitripennis
          Length = 418

 Score =  107 bits (258), Expect = 4e-22
 Identities = 47/97 (48%), Positives = 68/97 (70%), Gaps = 1/97 (1%)

Query: 315 YPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374
           + +TFI  I WI + SYL+ W   VVGDT+ +P  + GLT LAAGTS+P+ ++SV+V ++
Sbjct: 259 FAVTFIGSILWIAAYSYLMVWWANVVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARK 318

Query: 375 GHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTP 411
           G G M +S+S+GSN FD+ + L +PWL+  L Y  TP
Sbjct: 319 GFGDMAVSSSVGSNIFDVTVGLPVPWLLYGLIY-GTP 354



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 17/54 (31%), Positives = 32/54 (59%)

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           ++ + + I  ++ G TF+AA +S P+L  + +      GD+ V + VGS +F+V
Sbjct: 283 VVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDV 336


>UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep:
           CG12061-PB.3 - Drosophila melanogaster (Fruit fly)
          Length = 110

 Score =  104 bits (249), Expect = 5e-21
 Identities = 46/94 (48%), Positives = 62/94 (65%), Gaps = 1/94 (1%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L +  D+AGATF+AA++S+PELF+N VGTFVT GD+G+G +VGS+VFN+L +   C +F 
Sbjct: 17  LRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT 76

Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214
               +LDWW VTRD   Y      L   L D  +
Sbjct: 77  QPT-KLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
           G+ L +   + G T LAA TS PE   + + T   +G +G+   +GS+ F+IL+  G+  
Sbjct: 14  GNALRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCG 73

Query: 401 L----VKSLFYPSTPENHW 415
           +     K  ++P T +  W
Sbjct: 74  IFTQPTKLDWWPVTRDTAW 92


>UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger
           antiporter; n=1; Pirellula sp.|Rep: Probable
           sodium/calcium exchanger antiporter - Rhodopirellula
           baltica
          Length = 432

 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 82/343 (23%), Positives = 145/343 (42%), Gaps = 35/343 (10%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           G ++    + L C L++   C+ + + A E I    N++  + G T  A +SS PELF  
Sbjct: 2   GIVIPLVLIFLTC-LVIWRACDGFEI-ASEYIGR--NLSEGVRGGTINAISSSIPELFTT 57

Query: 146 CVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL-FAGAVI--------ELDWWSVT 192
            +  FV        +G+G   GSA+FN + +PA C L   G V+         +    + 
Sbjct: 58  LIALFVLSDRDGFSIGIGTTAGSALFNGMIIPAVCILSVVGFVVMGVRVTSVNVSTRVLL 117

Query: 193 RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGD 252
           RD +        LIL +  ++++W + L+L+LMY  Y++  +  + +S+        + D
Sbjct: 118 RDGISLILCEFILILLINGEQLHWWQGLILMLMYATYLVYMLTTMKSSELSANDEQPDND 177

Query: 253 LERGIEMTRR------HDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIP 306
            E   E  R       +  +G  +     W          K+  W   W + L     I 
Sbjct: 178 GEEEDESPRGPLASLFYWISGGPLLDLERWFVKDHHREQMKEETW-NGWGLLLTSTGVI- 235

Query: 307 DCRHRHSIYPLTFIMCITWIGS-VSYLVAWIITVVGDT---LNVPDSITGLTILAAGTSL 362
                 ++   T ++   W+GS  + +      + G T   L +P     +   +  TS+
Sbjct: 236 ------AMACWTLVLACEWLGSGPANVENPSYELFGQTFEGLGMPAMFVAVIFASMATSV 289

Query: 363 PEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           P+ V S+   + G     ++N++GSN FDI   LG P  + +L
Sbjct: 290 PDTVMSIRDARDGDYDDAVANALGSNIFDICFALGFPLFLYTL 332


>UniRef50_UPI000155609B Cluster: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           potassium-dependent sodium-calcium exchanger NCKX1 -
           Ornithorhynchus anatinus
          Length = 543

 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 37/81 (45%), Positives = 58/81 (71%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           + + S+LV      VG+T+ + + I GL+ILAAGTS+P+ ++SV+V ++G G M +S+S+
Sbjct: 392 VWAFSFLVFLWAAQVGETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSSSV 451

Query: 386 GSNTFDILLCLGLPWLVKSLF 406
           GSN FDI + L +PW + SLF
Sbjct: 452 GSNIFDITVGLPVPWFLYSLF 472



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 20/50 (40%), Positives = 32/50 (64%)

Query: 72  EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121
           E+P D  +  +R+ G++LLH     Y F+ L  VC++YFVPA+ +I  +L
Sbjct: 87  EYPEDVFSVEERRRGWVLLHVSGMAYVFVALAIVCDEYFVPALGVITAKL 136



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 176 CALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILE-KI 234
           CAL +  ++ L WW + RD   Y      LI    D  + W E+LLL+  Y  Y+   K 
Sbjct: 144 CALCSREILRLTWWPLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKW 203

Query: 235 N-PLDA 239
           N PL+A
Sbjct: 204 NRPLEA 209



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 16/51 (31%), Positives = 30/51 (58%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           E + I+ +I G + +AA +S P+L  + +      GD+ V + VGS +F++
Sbjct: 408 ETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 458


>UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_128,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 378

 Score = 77.8 bits (183), Expect = 5e-13
 Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 19/323 (5%)

Query: 95  ALYCFLLLGS--VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           AL+ ++L G   +  DY +P +E +  + ++ S+      MA   S PEL  N +  F +
Sbjct: 6   ALFFYVLSGQTYLSNDYLMPCLESLSTKWHL-SETGTGILMALGMSIPELTTNILSCFKS 64

Query: 153 EG-DLGVGAVVGSAVFNVLAVPACCALFAG----AVIELDWWSVTRDCMMYXXXXXXLIL 207
                G GA+VGS VF+        +LF+       + ++  ++ RD  +Y      L  
Sbjct: 65  SRIGYGFGAIVGSGVFDFTVCFGLMSLFSNYYHKRALRMNLKALMRDIYVYLLTLLFLTF 124

Query: 208 TLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTG 267
              D +I   EAL+L L Y  Y+L  +  ++        S Q       ++    H    
Sbjct: 125 VFWDYEISLTEALILTLFYPSYLLYSLVQMEQKDDF-QLSHQKHHFPTLLQFLDFHPEQA 183

Query: 268 SDISTSSV---WSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCIT 324
            D+             +++   ++   +L  P  L+   TIP  +H    + +    C  
Sbjct: 184 EDLDVDGKEIGQENQQEQVQEEQQPSKILL-PFTLLFKFTIP--KHPELAFIIISFYCFL 240

Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384
            +     +V   +    +  +V  +  GLTI + G ++ + +++ L  K     +  S+ 
Sbjct: 241 TVNVTMTVVDEFV----EQFSVSPAFVGLTIASWGGNIQDILNASLAAKNKKTELATSSI 296

Query: 385 IGSNTFDILLCLGLPWLVKSLFY 407
           IGS   ++ +CLG PW++  L +
Sbjct: 297 IGSQIMNLQICLGFPWVLTMLIW 319


>UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium
           difficile|Rep: Ca2+/Na+ antiporter - Clostridium
           difficile (strain 630)
          Length = 331

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 79/307 (25%), Positives = 134/307 (43%), Gaps = 45/307 (14%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           FI +  FL  +  +  G+   D F+     I ++ NI+  I GAT ++ A++ PE  ++ 
Sbjct: 2   FITVVLFLVGFLLITKGA---DIFINCTVEIGKKTNISEIILGATIVSFATTLPEFTVSL 58

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
           + +      + +G  VGS + N   +     +F      +D        ++       LI
Sbjct: 59  LASIDGHTTMSLGNAVGSIICNT-GLALGLVVFISP-FNVDKKMFFSKSLLLIVSVIVLI 116

Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDST 266
           L  LD  I   ++LLL+++  FY++     +        R+++N              +T
Sbjct: 117 LLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKNRNIKN--------------NT 162

Query: 267 GSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWI 326
             DIST    ++ G         F VL     L+L+AT               IM I  I
Sbjct: 163 IKDISTKKGKNYRG---------FSVLEIVKILLLFAT-------------GLIMMI--I 198

Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
           GS   + + +I  +   LN+P  I  LTI+A GTSLPE VSS+   ++ H  + + N +G
Sbjct: 199 GSQILIESGVI--IASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILG 256

Query: 387 SNTFDIL 393
           +N  +I+
Sbjct: 257 ANILNIV 263



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 23/59 (38%), Positives = 35/59 (59%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +G   N+ + I G TI++  T+LPE   S+L +  GH TM + N++GS   +  L LGL
Sbjct: 29  IGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGL 87



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 35/148 (23%), Positives = 62/148 (41%), Gaps = 4/148 (2%)

Query: 86  GFILLHCFLALYCF---LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPEL 142
           GF +L     L  F   L++  +     + +  II   LNI   I   T +A  +S PE+
Sbjct: 176 GFSVLEIVKILLLFATGLIMMIIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEI 235

Query: 143 FINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXX 202
             +         ++ VG ++G+ + N+++V A  A+     I L          M     
Sbjct: 236 VSSITAIRKNHHEISVGNILGANILNIVSVIAVSAIPNNIPI-LSQNRQLDIPFMILLLL 294

Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFYI 230
             +I TL  +K+   + +L++  Y  YI
Sbjct: 295 IVIIPTLKSNKLSRIQGILMLFTYFLYI 322


>UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium
           ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family
           transporter: sodium ion/calcium ion - Ostreococcus
           lucimarinus CCE9901
          Length = 603

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 9/146 (6%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG----T 149
           LAL  F  L SV E +FVPA+  I   L +  D+AGAT ++  + +P++F          
Sbjct: 95  LALTLFAALASVAERFFVPALRNIARGLALRDDVAGATLLSFGNGAPDIFAQIAALSHED 154

Query: 150 FVTEGDLGVGAVVGSAVFNVLAVPACCALFA-----GAVIELDWWSVTRDCMMYXXXXXX 204
                 L VGAV G+  F    V  C  L A     G  + LD W+  RD   Y      
Sbjct: 155 VAESAALAVGAVTGAGAFIASFVFPCVVLIATRAASGRGLVLDKWNFGRDVGFYAVASAM 214

Query: 205 LILTLLDDKIYWHEALLLVLMYTFYI 230
            +   LD ++  +EA  L  +Y  Y+
Sbjct: 215 ALGFFLDGRVEAYEAAALFSLYAAYL 240



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 302 WATIPDCRH-RHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360
           W+ I D    R  +  + F   I W+ + +  +  +++ +G    V +++ G T+LA G 
Sbjct: 422 WSHIGDVASIRALLVAVAFFQSILWMNTAASELVSLLSAIGKVTGVSEALLGATVLAWGN 481

Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394
           S+ + VS+ +V + G+  M I+        ++L+
Sbjct: 482 SVGDFVSNTVVARAGNPNMAIAACFAGPLMNLLV 515


>UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 1117

 Score = 69.7 bits (163), Expect = 1e-10
 Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 5/188 (2%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           +LL     L+ F  +G V  D+F P +  I  RL +    AG TF+A  + SP++F    
Sbjct: 181 LLLILMWMLFLFSWVGVVASDFFCPNLSTIASRLGLNESTAGVTFLAFGNGSPDVFSTFG 240

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207
                 G L +G ++G+A F V  +     L   A  +++ W   RD   +       + 
Sbjct: 241 AMKTDSGSLAIGELLGAASFIVSVISGSMMLI--APFKVNAWPFCRDVGFFTVAVALTLT 298

Query: 208 TLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTG 267
            L D K+   E + L+ +Y  Y    I     S     R  Q   LE   E   RH    
Sbjct: 299 FLFDGKLRRIETIALICLYLLYATTVI---IGSWWQERRRKQKRRLEVAREEYDRHADDR 355

Query: 268 SDISTSSV 275
           S +S  S+
Sbjct: 356 SILSRGSI 363



 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 319  FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
            F + + WI ++   V  I+  VG  + + D+I GLT+ A G SL + V+++ + K GH  
Sbjct: 950  FTVSVMWIMTIVDEVVSILQTVGIIVGLSDAILGLTVFAVGNSLGDLVANITIAKLGHPV 1009

Query: 379  MGISNSIGSNTFDILLCLGL--PWLV 402
            M IS        ++LL +G+   WL+
Sbjct: 1010 MAISACFAGPMLNLLLGIGISGTWLL 1035


>UniRef50_UPI000023E8AF Cluster: hypothetical protein FG08070.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG08070.1 - Gibberella zeae PH-1
          Length = 389

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 70/301 (23%), Positives = 122/301 (40%), Gaps = 16/301 (5%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV    I+  R  I   +     + A +   EL +           L VG ++GSA+ 
Sbjct: 26  DKFVDHTAIVAHRTGIPDTVIA--LLTAGAEWEELVVVIASLAQGRPSLAVGNIIGSAIS 83

Query: 168 NVLAVPACCALFA--GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEA-LLLVL 224
           N+L   +   LF   G+ +  D  S      +         +T    +I W     +L+ 
Sbjct: 84  NILGAFSLGLLFRPKGSHVTFDRSSRIYSLFLLIITTFVTPITYFSHRIIWLICGSILIA 143

Query: 225 MYTFYILE-----KINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFP 279
           ++  Y++          L A +     S  +      IE TR  +    +I  S     P
Sbjct: 144 LFAIYLISIGWAISRGSLTAPEGSDDDSSDDESDTSSIESTRSINRRRHEIQASQEEREP 203

Query: 280 GDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSI-YPLTFIMC-ITWIGSVSYLVAWII 337
            ++     +L   +      ++   +   R R S+ Y + F+M     I    Y++A   
Sbjct: 204 ENR----NELDQRVGGSAEGVVVTNVSSRRRRRSLGYHIGFLMLGFLAICLAGYVLAHAA 259

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
             + D + + D + G+ ILA  T+LPE   +VL   +GH  + ++N++GSN F + LCLG
Sbjct: 260 INITDAIGISDVLFGIIILAIATTLPEKFVAVLSGNRGHIGILVANTVGSNVFLLSLCLG 319

Query: 398 L 398
           +
Sbjct: 320 I 320


>UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 433

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 39/153 (25%), Positives = 73/153 (47%), Gaps = 2/153 (1%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L+ F++LG   +DYF P++ +I + L ++ ++AG TF+A  + +P++F + +      
Sbjct: 41  LMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIF-SAIAAVSAH 99

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
                 A +G+ +F    V     L  G    L+    TRD + Y      + +T+   +
Sbjct: 100 SKNPNAAQLGAGIFVTTVVVGSVTLCTGG-FHLNNRPFTRDVLFYLGAVSWMFITMYRQR 158

Query: 214 IYWHEALLLVLMYTFYILEKINPLDASQRMTPR 246
           I   EA+  ++ Y  Y++  I     +QR   R
Sbjct: 159 ITMLEAIGFIIFYFAYVVVVIVGRYVNQRWKRR 191



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 24/78 (30%), Positives = 37/78 (47%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L FI+ + WI   +  +  I+   G  L + ++I GLT LA G S+ + V+   + +QG 
Sbjct: 355 LAFIVSVVWIYVTANEIVNILQSFGIVLGLSNAILGLTFLAWGNSIGDLVADTTMARQGF 414

Query: 377 GTMGISNSIGSNTFDILL 394
             M      G     ILL
Sbjct: 415 PNMATGACFGGPMLSILL 432


>UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep:
           Predicted protein - Aspergillus oryzae
          Length = 363

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 68/298 (22%), Positives = 126/298 (42%), Gaps = 28/298 (9%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D F+    II +RL ++  +     + A +   EL +        +  L +G V+GS + 
Sbjct: 25  DKFIDHTVIIGQRLGVSQTLIAV--LTAGAEYEELAVVVAAVLQKQSPLALGNVMGSTIS 82

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD--DKIYWHEALLLVLM 225
           N+L   +   L     I  D  +     ++        ILT  +  +KI     + + LM
Sbjct: 83  NILGAFSLGLLLHPGPIAFDQSAKVYTALLLSITTAFYILTYFNMLNKITGGVLVAIFLM 142

Query: 226 Y---TFYILEK--INPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPG 280
           Y   T Y + K  + P +AS   +       D E     +R  DS   D S +S      
Sbjct: 143 YIICTCYAIHKGAMEPPEASDSDSDSDDDASDDEHSYSTSRPQDSRVQDESETSP----- 197

Query: 281 DKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVV 340
                      +LT    L+   + P     H    +  ++ +T  G   YL++   +V+
Sbjct: 198 -----------LLTHEEALVAKKSAPRSLFYHISQLVMGLLTLTISG---YLLSRSASVI 243

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
            D  ++  ++ GLT+++  T+LPE + +++   +GH  + ++++ GSN F + LC G+
Sbjct: 244 ADCFHLSGTVVGLTVVSFATTLPEKMVAIISGSRGHSGIVVASTAGSNIFLLTLCAGV 301


>UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus
           kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus
           kandleri
          Length = 329

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 67  PAAILEFPSDGLTRFQRQHGF-ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIAS 125
           P ++   P  G  R        +++ CF+  + FL       +  V A   +  +  ++ 
Sbjct: 6   PCSVRALPVRGSDRVDPWSALAVMMGCFVGFH-FL------SELLVDATVGLARKYGLSE 58

Query: 126 DIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
            +AGAT  A  +S+PE   +     +   ++GVG ++GSAV+NV  +P   AL AG  + 
Sbjct: 59  SVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAGG-LT 117

Query: 186 LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           L+     RD + Y      ++++L D  +   EAL  V +Y  Y+L
Sbjct: 118 LERAVYRRDVLFYLLALVVVLVSLWDRVVLRVEALAWVALYGLYVL 163



 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 28/79 (35%), Positives = 51/79 (64%)

Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380
           + +  I ++S L+        +   + +S   L + AAGTS+P+ ++SV   ++G G++ 
Sbjct: 193 VAVVGIAALSDLMVRATVDFCEGFGLSESRVSLLLNAAGTSVPDTLASVHAARRGFGSLA 252

Query: 381 ISNSIGSNTFDILLCLGLP 399
           +SN++GSNTFD+L+CLG+P
Sbjct: 253 VSNAVGSNTFDLLVCLGVP 271



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 17/51 (33%), Positives = 28/51 (54%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +S+ G T+ A GTS PE  SS+      H  +G+   +GS  +++ +  GL
Sbjct: 58  ESVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGL 108


>UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr8 scaffold_150, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 593

 Score = 67.3 bits (157), Expect = 7e-10
 Identities = 40/147 (27%), Positives = 78/147 (53%), Gaps = 3/147 (2%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           G+ +L  +LA+  F LLG+   +YF  ++E +   L ++  IAG T ++  + + ++F +
Sbjct: 110 GYTVLLLWLAVL-FYLLGNTAANYFCSSLENLSRVLKLSPTIAGVTLLSLGNGAADVFAS 168

Query: 146 CVG-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXX 203
            V  T  ++GD+G+  V+G A F    V    ++F G   I +D  S  RD + +     
Sbjct: 169 IVSFTRTSDGDVGLNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFFLIALA 228

Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI 230
            L++ ++  K+ +  ++  V +Y FY+
Sbjct: 229 SLLVIIIIGKVSFWGSVCFVSIYFFYV 255



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--H 376
           F+M +TW   ++  +  ++   G+ L +  ++ GLT+LA G SL + +++V +   G   
Sbjct: 435 FLMSVTWTYIIAEELVSLLVSFGNILGISPAVLGLTVLAWGNSLGDLIANVALAANGGQD 494

Query: 377 GT-MGISNSIGSNTFDILLCLGL 398
           G  + +S       F+ L+ LGL
Sbjct: 495 GVQIAVSGCYAGAMFNTLVGLGL 517


>UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein ncx-3 - Caenorhabditis elegans
          Length = 807

 Score = 67.3 bits (157), Expect = 7e-10
 Identities = 32/100 (32%), Positives = 60/100 (60%), Gaps = 2/100 (2%)

Query: 315 YPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374
           YP  F++ +  IG V+ +V  + ++ G  + + D++T +T++A GTSLP+  +S +  + 
Sbjct: 634 YPC-FVVALIGIGLVTAVVGDVASIFGCMVGLKDAVTAITLVALGTSLPDTFASKIAAES 692

Query: 375 GH-GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413
                  + N  GSN+ ++ L LGLPW++ SL++ S  E+
Sbjct: 693 DDTADNAVGNVTGSNSVNVFLGLGLPWVIASLYWASKGES 732



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 15/152 (9%)

Query: 127 IAGATFMAAASSSPELF---INCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
           +A  T MA  SS+PE+    I  VG     GDLG G +VGSA FN+  + A C    G  
Sbjct: 92  VANLTLMALGSSAPEILLSIIEIVGNGFKAGDLGPGTIVGSAAFNLFCISAICVFAVGTQ 151

Query: 184 ---IEL-DWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYILEKINPL 237
              IEL   + VT     +      L+L ++   +   W EA+L +L +   ++      
Sbjct: 152 TKRIELYRVFVVTAFFGTFAYIWVFLVLIVITPNVVDVW-EAILTLLFFIILVVVSY--- 207

Query: 238 DASQRMTPRSVQNGDLERGIEMTRRHDSTGSD 269
            A      +  ++ DL+  +EM  +HD    D
Sbjct: 208 -AVDAQIWKKKKSSDLQEELEMA-QHDGKVDD 237


>UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4;
           Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 344

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 29/71 (40%), Positives = 46/71 (64%)

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           L+   +T +  T ++P  + G+TILAA TSLP+A+ SV   + GHG   + N +GSNTFD
Sbjct: 207 LLVGAVTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLGSNTFD 266

Query: 392 ILLCLGLPWLV 402
           +L+ + +  L+
Sbjct: 267 LLVAIPIGVLI 277



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 31/103 (30%), Positives = 46/103 (44%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           A E +     + + + G+  +A  SS PEL    V        LGVGA+VGSA+FN+L V
Sbjct: 35  AAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVGAIVGSAIFNILVV 94

Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215
           P    +     ++     V ++   Y      L+LT     IY
Sbjct: 95  PGLAGITTTQPLDATRTVVYKEAQFYMLAVSTLLLTFALAVIY 137



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 24/78 (30%), Positives = 38/78 (48%)

Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163
           SV  +  V A+  +    +I S +AG T +AAA+S P+  ++        G   +G V+G
Sbjct: 202 SVAVELLVGAVTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLG 261

Query: 164 SAVFNVLAVPACCALFAG 181
           S  F++L       L AG
Sbjct: 262 SNTFDLLVAIPIGVLIAG 279



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGIS 382
           + W GS S+L A     +     +P  + G  ++A G+S PE +S ++    G   +G+ 
Sbjct: 24  LIWAGS-SWLEA-AAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVG 81

Query: 383 NSIGSNTFDILLCLGL 398
             +GS  F+IL+  GL
Sbjct: 82  AIVGSAIFNILVVPGL 97


>UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus
           ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter -
           Mariprofundus ferrooxydans PV-1
          Length = 322

 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 34/86 (39%), Positives = 50/86 (58%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F++ +  +   S +V W    +   L V D I GLTI+A GTSLPE V+S++   +G 
Sbjct: 174 LWFVVGLALLIISSRMVVWGAVEIAHLLGVSDLIIGLTIVAIGTSLPELVASLVSALKGE 233

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLV 402
             + I N IGSN F++L  L +P L+
Sbjct: 234 ADLAIGNVIGSNMFNLLAVLAMPALI 259



 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 28/63 (44%), Positives = 38/63 (60%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           V   L VP  + GLTI++ GTSLPE + S +    G+  +GI N +GSN  +I L LG+ 
Sbjct: 29  VAKNLRVPPMVIGLTIVSLGTSLPEMIVSAMAALDGNRDLGIGNVLGSNIANIGLVLGIT 88

Query: 400 WLV 402
            LV
Sbjct: 89  ALV 91



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           A+EI    L ++  I G T +A  +S PEL  + V     E DL +G V+GS +FN+LAV
Sbjct: 194 AVEI-AHLLGVSDLIIGLTIVAIGTSLPELVASLVSALKGEADLAIGNVIGSNMFNLLAV 252

Query: 173 PACCAL 178
            A  AL
Sbjct: 253 LAMPAL 258



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 20/71 (28%), Positives = 35/71 (49%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV     + + L +   + G T ++  +S PE+ ++ +       DLG+G V+GS + 
Sbjct: 20  DRFVDGAASVAKNLRVPPMVIGLTIVSLGTSLPEMIVSAMAALDGNRDLGIGNVLGSNIA 79

Query: 168 NVLAVPACCAL 178
           N+  V    AL
Sbjct: 80  NIGLVLGITAL 90


>UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep:
           F15I1.21 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 644

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 5/147 (3%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           G+ILL  +L    F LLG+   DYF  ++E + + L +   +AG T +   + +P++F +
Sbjct: 136 GYILLGVWLVAL-FYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS 194

Query: 146 CVGTFV--TEGDLGVGAVVGSAVFNVLAVPACCAL-FAGAVIELDWWSVTRDCMMYXXXX 202
            +  FV   +G++G+ +V+G AVF    V    +L  A   +++D     RD   +    
Sbjct: 195 -IAAFVGSDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTL 253

Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFY 229
             L++ L+  K+    A+  V +Y FY
Sbjct: 254 VALMVILMVGKVTVGIAIAFVSIYVFY 280



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 4/102 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHG- 377
           FIM I W   ++  +  ++   G    +  SI GLT+LA G S+ + VS++ ++  G   
Sbjct: 485 FIMSIVWFYMIANELVALLVTFGGIYGINPSILGLTVLAWGNSMGDLVSNIALSMNGGDG 544

Query: 378 -TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418
             + +S       F+ L+ LG+   + +  +  +PE + + +
Sbjct: 545 VQIALSGCYAGPMFNTLVGLGMSMFLGA--WSKSPETYMIPE 584


>UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr7 scaffold_42, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 560

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 6/129 (4%)

Query: 281 DKISFW-KKLFW-VLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIIT 338
           D I  W  ++FW +L  P R  L+A +P     H  +   FI  + +I  ++Y+V  +  
Sbjct: 356 DNIYLWVARIFWQLLLLPWRF-LFAFVPPPHIAHGWF--AFICSLIFISGIAYIVTKLTD 412

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           ++  T  +   +   T LAAGTS P+ V+S +   +Q      I+N I SN+ +I + +G
Sbjct: 413 LISCTSGINSYVIAFTALAAGTSWPDLVASKIAAERQTTADSAIANIICSNSVNIYMGIG 472

Query: 398 LPWLVKSLF 406
           +PWL+ + +
Sbjct: 473 IPWLINTTY 481


>UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4;
           Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
           - Methanosarcina acetivorans
          Length = 350

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 35/89 (39%), Positives = 50/89 (56%), Gaps = 5/89 (5%)

Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           + C   +    Y V   I    + L +PD++ G T++A GTSLPE V +V   +QG+G++
Sbjct: 213 LSCAAIVIGAKYFVEESI-FFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQGYGSI 271

Query: 380 GISNSIGSNTFDILLCLGLPWLVKSLFYP 408
            + N IGSN  +I L LGL      LFYP
Sbjct: 272 ALGNVIGSNITNIFLILGL----SGLFYP 296



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
           FL+ GS   DYFV +   I ++L ++  + G T +A  +S PEL  +   +      + +
Sbjct: 15  FLVKGS---DYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVI 71

Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218
           G VVGS + NV  +    AL +    E+D   + RD  +         +   + ++   E
Sbjct: 72  GNVVGSNIANVGLIVGVAALLSPMKTEID--MLKRDGYIMLFSAVLFFVFAFNRELSMLE 129

Query: 219 ALLLVLMYTFYI 230
           A L VL+Y  Y+
Sbjct: 130 AGLFVLLYIAYV 141



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 22/68 (32%), Positives = 39/68 (57%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           + +   L V + + GLT++A GTS+PE  SS+  + Q    + I N +GSN  ++ L +G
Sbjct: 28  STIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVIGNVVGSNIANVGLIVG 87

Query: 398 LPWLVKSL 405
           +  L+  +
Sbjct: 88  VAALLSPM 95



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 3/124 (2%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           YFV       E L I   + G T +A  +S PEL +         G + +G V+GS + N
Sbjct: 224 YFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQGYGSIALGNVIGSNITN 283

Query: 169 VLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           +  +     LF   +V E+  +  T   +M       LI      +I   E ++L++ Y 
Sbjct: 284 IFLILGLSGLFYPLSVAEMSLFFTTP--VMIAISLILLIFISTGWEIKRWEGVVLMMFYV 341

Query: 228 FYIL 231
            +++
Sbjct: 342 AFLV 345


>UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Firmicutes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Clostridium
           perfringens (strain SM101 / Type A)
          Length = 331

 Score = 64.5 bits (150), Expect = 5e-09
 Identities = 35/79 (44%), Positives = 48/79 (60%), Gaps = 4/79 (5%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L + + + GLTI+A GTSLPE V+S++  K+G   + + N +GSNTF+ILL LGL     
Sbjct: 213 LGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFNILLILGL----S 268

Query: 404 SLFYPSTPENHWVTDLYFI 422
           SL  P T       DL F+
Sbjct: 269 SLISPITIAASLSVDLIFL 287



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 51/190 (26%), Positives = 88/190 (46%), Gaps = 13/190 (6%)

Query: 97  YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           Y FL++G +      D FV     I ++L + + I G T ++  +S+PEL ++       
Sbjct: 3   YIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISAALKG 62

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL-----DW-WSVTRDCMMYXXXXXXLI 206
             D+ +G V+GS +FN+LA   C A+ A  VI+      D+  ++    ++Y      LI
Sbjct: 63  SNDITMGNVLGSNLFNLLAALGCTAIVAPLVIKKHIIKNDFIVNLLATFVLYVFTFTGLI 122

Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMT-RRHDS 265
            +   + +   + L+LVLM   YI+  I  +  S +         + E   E   +  +S
Sbjct: 123 GS--KNSLSRMDGLVLVLMCITYIIYLIYTVKRSHKKEDEVAVTVEFEDFEEKNIKSPNS 180

Query: 266 TGSDISTSSV 275
           TG +I  S V
Sbjct: 181 TGKNILLSIV 190



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 25/66 (37%), Positives = 36/66 (54%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +   L VP  I GLTI++ GTS PE   S+    +G   + + N +GSN F++L  LG  
Sbjct: 27  IAKKLGVPAVIIGLTIVSLGTSAPELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCT 86

Query: 400 WLVKSL 405
            +V  L
Sbjct: 87  AIVAPL 92



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 21/74 (28%), Positives = 36/74 (48%)

Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           V +   I   L ++  + G T +A  +S PEL  + V     E D+ +G ++GS  FN+L
Sbjct: 203 VDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFNIL 262

Query: 171 AVPACCALFAGAVI 184
            +    +L +   I
Sbjct: 263 LILGLSSLISPITI 276


>UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related
           family protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           K+-dependent Na+-Ca+ exchanger related family protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 325

 Score = 64.5 bits (150), Expect = 5e-09
 Identities = 29/73 (39%), Positives = 43/73 (58%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S ++ W    +   LN+ D I GLTI+A GTSLPE  SS++  ++    M + N +GSN 
Sbjct: 187 SRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNI 246

Query: 390 FDILLCLGLPWLV 402
           F+ L  +GL  L+
Sbjct: 247 FNALAVVGLSGLI 259



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I + LNI+  I G T +A  +S PEL  + V     + D+ +G +VGS +FN LAV    
Sbjct: 197 IAQALNISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNIFNALAVVGLS 256

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLL------DDKIYWHEALLLVLMYTFY 229
            L      E +   +TRD ++       L +  L      + ++     L+L+++Y  Y
Sbjct: 257 GLITPFAAEPE--ILTRDLVVMTIVTAVLFVMGLIRRRDHNAELKLAHGLILLIIYLLY 313



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 19/59 (32%), Positives = 31/59 (52%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408
           + G+ I+  GTS PE + SV      +  + + N+ GSN  +I L LG+  L+  +  P
Sbjct: 41  VIGIVIIGFGTSAPEMIVSVTAALNHNSGIALGNAYGSNIVNIGLILGISALIAPIPMP 99



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 2/132 (1%)

Query: 95  ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           A+   L+L     D+FV     + +   ++  + G   +   +S+PE+ ++         
Sbjct: 9   AIIIGLILLVKSADWFVDGAAALAKIAGLSPLVIGIVIIGFGTSAPEMIVSVTAALNHNS 68

Query: 155 DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214
            + +G   GS + N+  +    AL   A I +    V+ +  +         L L DD I
Sbjct: 69  GIALGNAYGSNIVNIGLILGISALI--APIPMPKKLVSGELFILLLITLLCFLWLQDDYI 126

Query: 215 YWHEALLLVLMY 226
              EAL++++++
Sbjct: 127 SRSEALVMLVLF 138


>UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6;
           Trichocomaceae|Rep: Sodium/calcium exchanger protein -
           Aspergillus clavatus
          Length = 994

 Score = 64.5 bits (150), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 51/89 (57%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F++ I WI +++  V  ++  VG  LN+ DS+ GLT+ A G SL + V+ + V + G+
Sbjct: 833 LGFVVAIFWIATIATEVVSLLKTVGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 892

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSL 405
             M +S   G    +ILL +GL  L  +L
Sbjct: 893 PVMALSACFGGPMLNILLGIGLGGLYMTL 921



 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 3/145 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           FI+L  +L+L  F  +G    D+    +  +   L ++  + G TF+A  + SP++F   
Sbjct: 114 FIILILWLSLL-FSTIGIAASDFLCIDLSTLASILGMSESLTGVTFLAFGNGSPDVFSTF 172

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                  G L +G ++G+A F    V    AL      ++   S  RD   +       +
Sbjct: 173 AAMRSNSGSLAIGELLGAASFITSVVAGSMALV--QPFKVARRSFVRDVGYFVIAVSFSM 230

Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231
           + L D +++  E+  +V +Y FY++
Sbjct: 231 VLLADGRLHVWESAAMVGLYCFYVV 255



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367
           PL FI+ I W+         + S  +   ++ +   L + +S+TG+T LA G   P+  S
Sbjct: 111 PLAFIILILWLSLLFSTIGIAASDFLCIDLSTLASILGMSESLTGVTFLAFGNGSPDVFS 170

Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           +    +   G++ I   +G+ +F   +  G   LV+
Sbjct: 171 TFAAMRSNSGSLAIGELLGAASFITSVVAGSMALVQ 206


>UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7
           precursor (Na(+)/Ca(2+)-exchange protein 7); n=2;
           Caenorhabditis|Rep: Putative sodium/calcium exchanger 7
           precursor (Na(+)/Ca(2+)-exchange protein 7) -
           Caenorhabditis elegans
          Length = 672

 Score = 64.5 bits (150), Expect = 5e-09
 Identities = 32/87 (36%), Positives = 51/87 (58%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FIM I WI  +S  V  ++T++G    V   + GLTILA   S+ + ++ V V KQG+  
Sbjct: 518 FIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPR 577

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405
           M ++ +IG   F++L+  GLP+ +  L
Sbjct: 578 MAMAAAIGGPLFNLLMGFGLPFTIAKL 604



 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 6/151 (3%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---I 144
           I++     L  F+++ S  +D+F P+I  I   L I+  +AG TFMA  + +P++F    
Sbjct: 91  IIVGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIA 150

Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204
           + + +   + DL +G + G  +F    V +   L +   +E+  +S  RD + Y      
Sbjct: 151 SVLSSPTPKADLALGELFGGGLFVTTMVVSTIILTSPFDVEV--FSTIRDLLFYLVALSF 208

Query: 205 LILT-LLDDKIYWHEALLLVLMYTFYILEKI 234
           L    +  +++     L  + +Y  Y++  I
Sbjct: 209 LAFCFVFYNRVTLWMPLTFLGLYLLYVITVI 239


>UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:
           CG5685-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 950

 Score = 64.1 bits (149), Expect = 7e-09
 Identities = 29/94 (30%), Positives = 54/94 (57%), Gaps = 1/94 (1%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           +TF++ I  IG ++ ++    +  G  LN+ DS+T +  +A GTS+P+  +S++  K   
Sbjct: 779 VTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDE 838

Query: 377 GTMG-ISNSIGSNTFDILLCLGLPWLVKSLFYPS 409
           G    I N  GSN  ++ L +GL W + ++++ S
Sbjct: 839 GADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSS 872



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 3/59 (5%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTE---GDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           +A  T MA  SS+PE+ ++ +  +  +   GDLG G +VGSA +N+  + A C ++  A
Sbjct: 180 VANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPA 238


>UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1;
           Aspergillus oryzae|Rep: K+-dependent Na+:Ca2+ antiporter
           - Aspergillus oryzae
          Length = 785

 Score = 64.1 bits (149), Expect = 7e-09
 Identities = 32/89 (35%), Positives = 51/89 (57%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L FI+ I WI +++  V  ++  +G  LN+ DS+ GLT+ A G SL + V+ + V + G+
Sbjct: 624 LGFIVAICWIATIATEVVSLLKTLGVILNISDSLLGLTVFAVGNSLGDLVADITVARLGY 683

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSL 405
             M +S   G    +ILL +GL  L  +L
Sbjct: 684 PVMALSACFGGPMLNILLGIGLGGLYMTL 712


>UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+
           antiporter, CaCA family - Fervidobacterium nodosum
           Rt17-B1
          Length = 314

 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 39/113 (34%), Positives = 62/113 (54%), Gaps = 7/113 (6%)

Query: 318 TFIMCITWIGSVSYLV---AWIITVVGD---TLNVPDSITGLTILAAGTSLPEAVSSVLV 371
           T I  +  IG ++ LV    WI+    D      V D + GLTI+AAGTS+PE  +S+  
Sbjct: 169 TIISILYIIGGLAGLVFGGRWIVNGAVDIAKAFGVSDKLIGLTIVAAGTSIPELATSLAA 228

Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRI 424
             +G+  + + N++GSN F++   LG+  ++K + Y +T  N  VT L  I +
Sbjct: 229 IIKGNNEIALGNAVGSNIFNVFFILGISAVIKPIVY-TTVLNFDVTLLVIITV 280



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 25/98 (25%), Positives = 52/98 (53%), Gaps = 1/98 (1%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           ++L   L +  F+ + S+  D  V     + ++L ++  + G T +A  +S+PEL +N V
Sbjct: 1   MILSILLLIIGFVFV-SIGSDKLVEGASTLAKKLKVSDLLIGLTIVAFGTSAPELAVNIV 59

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
            +     ++ +G V+GS +FN+L V    A+    +++
Sbjct: 60  SSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPVIVQ 97



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 24/60 (40%), Positives = 39/60 (65%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L V D + GLTI+A GTS PE   +++ + +G   + + N IGSN F+IL+ +GL  +++
Sbjct: 33  LKVSDLLIGLTIVAFGTSAPELAVNIVSSIKGTSNISLGNVIGSNIFNILVVVGLSAVIR 92



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I +   ++  + G T +AA +S PEL  +         ++ +G  VGS +FNV  +    
Sbjct: 197 IAKAFGVSDKLIGLTIVAAGTSIPELATSLAAIIKGNNEIALGNAVGSNIFNVFFILGIS 256

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           A+    V       +  D  +       L+L   + KI   E LL+V  Y  Y +
Sbjct: 257 AVIKPIVYTT---VLNFDVTLLVIITVILLLFSKNLKIEKFEGLLMVSTYVGYTI 308


>UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum
           symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum
           symbiosum
          Length = 294

 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 27/83 (32%), Positives = 52/83 (62%)

Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGIS 382
           +  +G+ ++L      V+     + + + G T++A GTSLPE V+SV+  K+GH  +G+ 
Sbjct: 161 VALLGAGAWLAVENAVVLARAFGLSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVG 220

Query: 383 NSIGSNTFDILLCLGLPWLVKSL 405
           N IGSN ++IL+ +G+  ++ ++
Sbjct: 221 NIIGSNIYNILMIMGVASMIAAV 243



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 17/69 (24%), Positives = 35/69 (50%)

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           ++     ++  + G T +A  +S PEL  + V       D+GVG ++GS ++N+L +   
Sbjct: 177 VLARAFGLSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGV 236

Query: 176 CALFAGAVI 184
            ++ A   +
Sbjct: 237 ASMIAAVPV 245



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 18/67 (26%), Positives = 39/67 (58%), Gaps = 4/67 (5%)

Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           W+++   ++     +   + G+T++A GTS PE  +S+  + + HG + + N IGSN  +
Sbjct: 8   WLVSGGVMLARRFGISSLVIGMTVVAYGTSTPELAASLAASGE-HGELILGNVIGSNIAN 66

Query: 392 ILLCLGL 398
           + + +G+
Sbjct: 67  VGMIIGI 73


>UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6); n=2;
           Caenorhabditis|Rep: Putative sodium/calcium exchanger 6
           precursor (Na(+)/Ca(2+)-exchange protein 6) -
           Caenorhabditis elegans
          Length = 590

 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 30/87 (34%), Positives = 51/87 (58%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F+M I WI  +S  V  ++T++G    V   + GLTILA   S+ + ++ V V KQG+  
Sbjct: 436 FLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPR 495

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405
           M ++ +IG   F++L+  GLP+ +  +
Sbjct: 496 MAMAAAIGGQLFNLLIGFGLPFTIAKI 522



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 3/75 (4%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---INCVGTFVT 152
           L  F+++ S  +D+F P+I  I   L I+  +AG TFMA  + +P++F    + + +   
Sbjct: 108 LVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTP 167

Query: 153 EGDLGVGAVVGSAVF 167
           + DL +G + G+ +F
Sbjct: 168 KADLALGELFGAGLF 182


>UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 441

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 29/109 (26%), Positives = 60/109 (55%), Gaps = 1/109 (0%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           +++A +P     +S   +TF++ + +I  ++ ++  + T+ G  + +   +T +T +A G
Sbjct: 252 VIFACVPPPHFLNSRGYITFVVALCFIAVLTAIIGDLATIFGCLIGLLAPVTAITFVALG 311

Query: 360 TSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           TSLP+   S      +      I N  GSN+ ++ L LGLPWL+ ++++
Sbjct: 312 TSLPDTFASKTAAVNEATADNSIGNVTGSNSVNVFLGLGLPWLIAAIYW 360


>UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis
           thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 570

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 45/180 (25%), Positives = 86/180 (47%), Gaps = 7/180 (3%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           G ++L  +L +  F LLG     YF P+++ + + L ++  +AG T ++  + +P+LF +
Sbjct: 101 GHLVLSAWLFVL-FYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSS 159

Query: 146 CVG-TFVTEGDLGVGAVVGSAVF-NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXX 203
            V  T    GD G+ +++G A F +   V   C L     + +D  S  RD +       
Sbjct: 160 VVSFTRSNNGDFGLNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALC 219

Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI--LEKINPLDASQRMTPRSVQNGD--LERGIEM 259
            L L +   K+    AL  + +Y  Y+  L   +  D  +RM+ + +++ +   E G+ +
Sbjct: 220 CLGLIIFIGKVTIWVALCYLSIYLLYVGFLSVSHFFDRKKRMSDQILRSREDLAEMGVSL 279



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 4/94 (4%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--- 375
           F M +TW   ++  +  ++  +G+   +  S+ GLT+LA G SL + +++V V   G   
Sbjct: 410 FTMSVTWTYMIAQELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAFHGGND 469

Query: 376 HGTMGISNSIGSNTFDILLCLGLPWLVKSLF-YP 408
              + +S       F+ ++ LG+P ++ SL  YP
Sbjct: 470 GAQIALSGCYAGPLFNTVIGLGVPLVISSLAEYP 503


>UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein;
           n=1; Clostridium tetani|Rep: Putative sodium/calcium
           exchanger protein - Clostridium tetani
          Length = 347

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 76/311 (24%), Positives = 133/311 (42%), Gaps = 51/311 (16%)

Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE--GDLGVGAV 161
           S   D    A+ I+  +L I + + GATF A +SS PE     +   V +   D+GV  +
Sbjct: 26  SKASDKLGDALHILGVKLKIPTSVRGATFDAISSSFPEFSTAMIAVIVYKRFTDVGVPTI 85

Query: 162 VGSAVFNVLAVP-ACCALFAG--AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218
            GS VFN+L +P A    + G   +I++D   V RD + Y      L+            
Sbjct: 86  AGSGVFNILIIPMATIFAYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYLGSYTVFA 145

Query: 219 ALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSF 278
            ++LVL+Y  YI      L    +   +++         E  + ++   +++ T    S+
Sbjct: 146 GIVLVLIYIGYIF----VLYGETKNYRKNIS--------EENKAYEEIAAELDTEEDMSY 193

Query: 279 PGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIIT 338
                    K+F ++   I LI W +I        I   T I   T+     Y+V+  + 
Sbjct: 194 --------LKIFIIMAITIALI-WVSIDGI-----IQSTTVIS--TFFNIPQYIVS--VV 235

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           ++    ++PD     T+L+  +S           + G     ++N++GSN FDI +CLG+
Sbjct: 236 IIAACTSIPD-----TLLSIKSS-----------QDGDVEGAVANAVGSNIFDICICLGV 279

Query: 399 PWLVKSLFYPS 409
           P ++     P+
Sbjct: 280 PIIIAGKTLPA 290


>UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyces
           pombe CaCA sodium/calcium exchanger; n=1; Yarrowia
           lipolytica|Rep: Similar to tr|P87122 Schizosaccharomyces
           pombe CaCA sodium/calcium exchanger - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 812

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 3/148 (2%)

Query: 84  QHGFILLHCFL-ALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPEL 142
           Q  F+L+   L  L  F+ LG    D+  P +  I   L ++  +AG TF+A  + SP+L
Sbjct: 92  QRPFLLIMLLLWLLTLFMTLGIAASDFLCPNLGTISSLLGMSESLAGVTFLAFGNGSPDL 151

Query: 143 FINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXX 202
           F       +  G L +G ++G+A F    V    AL      ++   S  RD   +    
Sbjct: 152 FSTYSSMKIGSGSLAIGELIGAASFISAVVVGAMAL--ARPFKVARKSFVRDIGFFTAAV 209

Query: 203 XXLILTLLDDKIYWHEALLLVLMYTFYI 230
              +  + D K+   E +L++++Y  Y+
Sbjct: 210 LCTMAFISDGKLRRSECILMLIIYMIYV 237



 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F+  I W+  ++ +V  ++  +G  L + D + GLT+ A G SL + +++  + K G   
Sbjct: 659 FLTSIAWVSHIADVVVGVLKALGAILGISDPVLGLTVFAFGNSLGDLIANTTIAKMGFPM 718

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRIN 425
           M +S   G    ++L+ +G    V  L   S+P N      Y I I+
Sbjct: 719 MALSACFGGPLLNVLVGVG----VSGLIVTSSPGNAVKNGSYHIEIS 761



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 17/58 (29%), Positives = 30/58 (51%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           +   L + +S+ G+T LA G   P+  S+    K G G++ I   IG+ +F   + +G
Sbjct: 126 ISSLLGMSESLAGVTFLAFGNGSPDLFSTYSSMKIGSGSLAIGELIGAASFISAVVVG 183


>UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 1004

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 3/145 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F LL  +LAL  F  +G    D+F   +  I   L ++  +AG TF+A  + SP++F   
Sbjct: 101 FGLLAAWLALL-FTTIGIAASDFFSINLSTIASILGLSESLAGVTFLAFGNGSPDVFSTF 159

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                  G + VG ++G+A F    V    AL      ++   +  RD   +       +
Sbjct: 160 AAMGSNSGSMAVGELIGAAGFITAVVAGSMALV--REFKVVKRTFVRDICFFILAASFAM 217

Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231
             L D  +++ E +++V  Y FY++
Sbjct: 218 AVLADGHLHFWECIIMVAFYIFYVM 242



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 34/104 (32%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 297 IRLILWATIPDCRHR-HSIYP-LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLT 354
           + L+L +T P+ R R H ++  L FI+ + WI +V+  V  ++   G  L + ++I GLT
Sbjct: 809 LALLLSSTSPNVRPRYHFLFCFLGFIISVAWISTVAGEVVGVLKAFGVILGISEAILGLT 868

Query: 355 ILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           I A G SL + V+ + V + G+  M ++   G    +ILL +G+
Sbjct: 869 IFAVGNSLGDLVADITVARLGYPVMALAACFGGPMLNILLGIGI 912



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 17/67 (25%), Positives = 31/67 (46%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           ++ +   L + +S+ G+T LA G   P+  S+        G+M +   IG+  F   +  
Sbjct: 127 LSTIASILGLSESLAGVTFLAFGNGSPDVFSTFAAMGSNSGSMAVGELIGAAGFITAVVA 186

Query: 397 GLPWLVK 403
           G   LV+
Sbjct: 187 GSMALVR 193


>UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca
           exchanger - Aedes aegypti (Yellowfever mosquito)
          Length = 583

 Score = 62.5 bits (145), Expect = 2e-08
 Identities = 34/144 (23%), Positives = 74/144 (51%), Gaps = 3/144 (2%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           + L  F+ + CF +L +  + +F P + +I + L+I+  +AG T +A  + SP+LF   V
Sbjct: 77  VALLTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLF-TAV 135

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207
                + +L  G ++G+ +F V+ + A   L       +   +V RD + +      + +
Sbjct: 136 SNPNDDTELMFGELLGAGLF-VVGIVAGTILVI-RPFHVYSAAVVRDVVFFIFAVSWITV 193

Query: 208 TLLDDKIYWHEALLLVLMYTFYIL 231
              D++    +A+++V++Y  Y++
Sbjct: 194 CAYDERFTLSDAIVVVVVYVLYLV 217



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 1/94 (1%)

Query: 312 HSIYPL-TFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVL 370
           H +Y L  F+  I  I  V+  V  ++  +G  L +  S+ GL++LA G S+ +  S++ 
Sbjct: 407 HLVYALLAFVGSIQVIYVVAQEVVSLLMTLGLVLELSKSMLGLSVLAWGNSIGDLFSNIA 466

Query: 371 VTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           + K+G+G M  +   G   F++ L LG   +V++
Sbjct: 467 LAKRGYGKMAFAACFGGPLFNLCLGLGSTMIVRA 500



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 317 LTF--IMCITWIGSVS-YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369
           LTF  I+C T + + +      ++ V+  TL++ +S+ G+TILA G   P+  ++V
Sbjct: 80  LTFMLILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLFTAV 135


>UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family
           transporter precursor; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Ca2+:cation antiporter (CaCA) family
           transporter precursor - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 329

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 26/71 (36%), Positives = 44/71 (61%)

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           ++ W    + +  +VP+ I GLTI+A GTSLPE  +++   K+G   + I N +GSN F+
Sbjct: 196 MMVWGAVEIAEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKKGEADLMIGNILGSNLFN 255

Query: 392 ILLCLGLPWLV 402
           +L  + +P L+
Sbjct: 256 LLAVMSMPALI 266



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           A+EI  E  ++   I G T +A  +S PEL          E DL +G ++GS +FN+LAV
Sbjct: 201 AVEI-AEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKKGEADLMIGNILGSNLFNLLAV 259

Query: 173 PACCALFAGAVIE 185
            +  AL A +VI+
Sbjct: 260 MSMPALIAPSVID 272



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 20/67 (29%), Positives = 36/67 (53%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           +N+   I G+ +L  GTS PE + ++L +      + I N +GSN  +I L LG+  ++ 
Sbjct: 37  MNISPLIIGVVVLGFGTSAPEILVAILASIDNSPGLAIGNVVGSNIANIGLVLGVTAIIS 96

Query: 404 SLFYPST 410
            +   S+
Sbjct: 97  PVVIKSS 103



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 8/163 (4%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           + L+  L L     D F+         +NI+  I G   +   +S+PE+ +  + +    
Sbjct: 10  IVLFVGLALLVWSSDIFIEGAASTAIHMNISPLIIGVVVLGFGTSAPEILVAILASIDNS 69

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD-- 211
             L +G VVGS + N+  V    A+ +  VI+     + R+  +        IL +LD  
Sbjct: 70  PGLAIGNVVGSNIANIGLVLGVTAIISPVVIKSS--LLKREFPILLGISLVGILLMLDKD 127

Query: 212 ----DKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQN 250
               D I     LL+V+ +     + I+P D     T   +++
Sbjct: 128 LDITDGIILLALLLIVMTWMIRANKNISPSDPLAEETIEEIED 170


>UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein;
           n=1; marine gamma proteobacterium HTCC2080|Rep: Putative
           sodium/calcium exchanger protein - marine gamma
           proteobacterium HTCC2080
          Length = 321

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 1/85 (1%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           IGS   LV W    + ++  V + + GLTI+A GTSLPE  +S++   +GH  + I   +
Sbjct: 179 IGSSKALV-WAAVNIAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGAVV 237

Query: 386 GSNTFDILLCLGLPWLVKSLFYPST 410
           GSN F++L+ L +P L   L   +T
Sbjct: 238 GSNMFNLLIVLAIPGLFSPLELSTT 262



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I E   ++  + G T +A  +S PEL  + V       D+ +GAVVGS +FN+L V A  
Sbjct: 192 IAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGAVVGSNMFNLLIVLAIP 251

Query: 177 ALFAGAVIELDWWSVTRD 194
            LF  + +EL    + RD
Sbjct: 252 GLF--SPLELSTTDLQRD 267



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 21/61 (34%), Positives = 34/61 (55%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409
           I G+T+++ GTS PE + S+     G G + + N+ GSN  +I L LGL  ++  +    
Sbjct: 39  IIGMTVVSLGTSAPEILVSLSAAASGAGALAVGNAFGSNIANIGLVLGLTLIISPILVGR 98

Query: 410 T 410
           T
Sbjct: 99  T 99



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 16/62 (25%), Positives = 29/62 (46%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D F+     +  R  ++  I G T ++  +S+PE+ ++        G L VG   GS + 
Sbjct: 20  DLFIKGAAAVASRFGMSPLIIGMTVVSLGTSAPEILVSLSAAASGAGALAVGNAFGSNIA 79

Query: 168 NV 169
           N+
Sbjct: 80  NI 81


>UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 858

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 3/144 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F +L  +LA+  F  +G    D+    +  I   L ++  + G TF+A  + SP++F   
Sbjct: 175 FAILAVWLAVL-FNTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFSTF 233

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                  G L +G +VG+A F    V    AL       +   S  RD + +       +
Sbjct: 234 AAMNSNSGGLAIGELVGAAGFITAVVAGSMALV--RPFRVARRSFVRDVVFFVFSASFTM 291

Query: 207 LTLLDDKIYWHEALLLVLMYTFYI 230
           + L D K+Y  E + ++L Y FY+
Sbjct: 292 VLLADGKLYAWECVAMILSYVFYV 315



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 32/97 (32%), Positives = 54/97 (55%)

Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           R R  +  L F++ I WI +++  V  ++  +G  L++ DS+ GLTI A G SL + V+ 
Sbjct: 675 RFRPFVAFLGFVVSIAWISTLASEVVNLLKAIGVILSISDSLLGLTIFAVGNSLGDLVAD 734

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           + V + G+  M +S   G    +ILL +G+  L  +L
Sbjct: 735 ITVARLGYPVMALSACFGGPMLNILLGVGMGGLYMTL 771



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 9/104 (8%)

Query: 308 CRHRHSIYPLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           C+  H+  P+ F +   W+         + S  +   ++ +   L + +S+TG+T LA G
Sbjct: 165 CKLAHA-KPIAFAILAVWLAVLFNTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFG 223

Query: 360 TSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
              P+  S+        G + I   +G+  F   +  G   LV+
Sbjct: 224 NGSPDVFSTFAAMNSNSGGLAIGELVGAAGFITAVVAGSMALVR 267


>UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep:
           Uvs037 - uncultured bacterium
          Length = 354

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 29/60 (48%), Positives = 42/60 (70%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           V +++ GLTI+AAGTSLPE V+SV+ T +G   + + N +GSN F+IL  LG+  LV  +
Sbjct: 201 VNEAVIGLTIVAAGTSLPEVVTSVVATIKGERDIAVGNVVGSNIFNILCVLGISGLVSPI 260



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 26/60 (43%), Positives = 35/60 (58%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           VP  + GLT++A GTS PE   SV     G   + I+N +GSN F+IL  LG+  L+  L
Sbjct: 33  VPALVIGLTVVAFGTSAPELAVSVKAAFSGQAELAIANVVGSNIFNILFILGVAALISPL 92



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 5/141 (3%)

Query: 93  FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           ++ L+  L+L  +  D  V     +     + + + G T +A  +S+PEL ++    F  
Sbjct: 3   WVLLFAGLVLLVIGADLLVKGAARLAANFGVPALVIGLTVVAFGTSAPELAVSVKAAFSG 62

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
           + +L +  VVGS +FN+L +    AL +  +I      + +D  +        +L  LD 
Sbjct: 63  QAELAIANVVGSNIFNILFILGVAALISPLIISHQ--LIRQDVPIMVGVSIVAVLMTLDG 120

Query: 213 KIYWHEALLL---VLMYTFYI 230
            I   EA +L   ++ YT+++
Sbjct: 121 NINKLEASILTIGLISYTWFL 141



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 21/46 (45%), Positives = 29/46 (63%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           + G T +AA +S PE+  + V T   E D+ VG VVGS +FN+L V
Sbjct: 205 VIGLTIVAAGTSLPEVVTSVVATIKGERDIAVGNVVGSNIFNILCV 250


>UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Marinomonas sp. MWYL1
          Length = 332

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           IGS S L+ W    +   L V + + GLTI+A GTSLPE  +SV   ++GH  + I N +
Sbjct: 193 IGS-SKLLVWGAIGIATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIAIGNIL 251

Query: 386 GSNTFDILLCLGLPWLV 402
           GSN F++   L LP L+
Sbjct: 252 GSNIFNLATVLPLPALL 268



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 26/91 (28%), Positives = 47/91 (51%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           +AL   L+L  +  D F+    ++ E+LN+   I G T +A  +S+PE+ ++ +      
Sbjct: 18  IALIVGLILLVMSSDKFIEHSALVAEKLNVNPMIIGITLVAFGTSAPEMVVSAIAALDNA 77

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
            ++ VG V+GS + N+  V     LF+   I
Sbjct: 78  PEIAVGNVLGSNIANIALVFGITLLFSAIPI 108



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 23/67 (34%), Positives = 36/67 (53%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +V + LNV   I G+T++A GTS PE V S +        + + N +GSN  +I L  G+
Sbjct: 40  LVAEKLNVNPMIIGITLVAFGTSAPEMVVSAIAALDNAPEIAVGNVLGSNIANIALVFGI 99

Query: 399 PWLVKSL 405
             L  ++
Sbjct: 100 TLLFSAI 106



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 19/69 (27%), Positives = 34/69 (49%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I   L ++  + G T +A  +S PEL  +         D+ +G ++GS +FN+  V    
Sbjct: 206 IATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIAIGNILGSNIFNLATVLPLP 265

Query: 177 ALFAGAVIE 185
           AL A  +++
Sbjct: 266 ALLAPGLVD 274


>UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 320

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 29/67 (43%), Positives = 39/67 (58%)

Query: 333 VAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDI 392
           V W  + +  TL V D + GLT++A GTSLPE  +SV    +G   M I N +GSN F++
Sbjct: 186 VVWGASEIASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNL 245

Query: 393 LLCLGLP 399
           L  L  P
Sbjct: 246 LAVLPFP 252



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 21/62 (33%), Positives = 35/62 (56%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + V   + G+ I+  GTS PE + S +    G G + + N++GSN  +I L LG+  L+K
Sbjct: 35  MGVSPLLVGMLIVGLGTSAPEMLVSAMAALDGSGGIALGNAVGSNITNIGLVLGVSALIK 94

Query: 404 SL 405
            +
Sbjct: 95  PI 96



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 26/127 (20%), Positives = 55/127 (43%), Gaps = 2/127 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV     +  R+ ++  + G   +   +S+PE+ ++ +      G + +G  VGS + 
Sbjct: 22  DRFVFGASTLARRMGVSPLLVGMLIVGLGTSAPEMLVSAMAALDGSGGIALGNAVGSNIT 81

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  V    AL     +  D   V R+  +       ++L L+D ++   +  +LV    
Sbjct: 82  NIGLVLGVSALIKPIRLHRD--VVRREIPVVLLITFGVVLLLVDWQLRPVDGAILVATLI 139

Query: 228 FYILEKI 234
            +++  I
Sbjct: 140 LFLVRAI 146



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 20/56 (35%), Positives = 30/56 (53%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I   L ++  + G T +A  +S PEL  +       E  + +G V+GS VFN+LAV
Sbjct: 193 IASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNLLAV 248


>UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+
           antiporter, CaCA family - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 296

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 23/60 (38%), Positives = 42/60 (70%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           ++     + + I GLT++A GTSLPE ++S++  ++GH  +G+ N IGSN ++IL+ +G+
Sbjct: 179 ILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILMIMGV 238



 Score = 46.4 bits (105), Expect = 0.001
 Identities = 21/72 (29%), Positives = 37/72 (51%)

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           I+ +   ++  I G T +A  +S PEL  + +       D+GVG ++GS ++N+L +   
Sbjct: 179 ILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILMIMGV 238

Query: 176 CALFAGAVIELD 187
            A   G +I  D
Sbjct: 239 GAALGGVMISDD 250



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 4/67 (5%)

Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           W+++    +     + + + G+TI+A GTS PE  +S+    + H  + + N IGSN  +
Sbjct: 8   WLVSGGVAIARKFRISNLVIGMTIVAYGTSTPELAASIAAAGE-HSAIILGNIIGSNIAN 66

Query: 392 ILLCLGL 398
           + + +G+
Sbjct: 67  VGMVIGI 73


>UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to
           sodium-calcium exchanger; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to sodium-calcium
           exchanger - Strongylocentrotus purpuratus
          Length = 766

 Score = 60.9 bits (141), Expect = 6e-08
 Identities = 34/119 (28%), Positives = 69/119 (57%), Gaps = 4/119 (3%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           +++A +P  ++    +P  F+  + +I +++ +V  I T++     +  S+ G+TI+A G
Sbjct: 583 VIFAMVPP-KNYFGGWP-AFLGSLLFIFALTAVVEQIATLLSCVALIEPSVAGITIIALG 640

Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLF-YPSTPENHWV 416
           TS+P+  +S     Q  H    I N  GSN+ ++ L LGLPW++K ++ Y ++ + ++V
Sbjct: 641 TSVPDTFASRTAAIQDQHADAAIGNITGSNSVNVFLGLGLPWIIKVMYLYVNSDQPYYV 699



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 7/59 (11%)

Query: 127 IAGATFMAAASSSPELFINCVGTF--VTE-----GDLGVGAVVGSAVFNVLAVPACCAL 178
           +A  T MA  SS+PE+ +N V T   +TE       LG   ++GSA FN+L + A C +
Sbjct: 103 VANLTLMALGSSAPEILLNTVETLQNLTEPPNRKDSLGTFTIIGSAAFNLLIITAVCVV 161


>UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=2; Chlorobiaceae|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Chlorobium phaeobacteroides BS1
          Length = 325

 Score = 60.9 bits (141), Expect = 6e-08
 Identities = 31/83 (37%), Positives = 49/83 (59%), Gaps = 3/83 (3%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + + L +P  I GLT++A GTSLPE V+S++ T QG   + + N +GSN F++LL  G  
Sbjct: 206 IAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNG-- 263

Query: 400 WLVKSLFYPSTPENHWVTDLYFI 422
            +  S+   + P N    DL+ +
Sbjct: 264 -VCSSITQIAVPVNGGFYDLFMM 285



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 4/120 (3%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I E L I   I G T +A  +S PEL  + V TF  + D+ VG VVGS +FN+L V   C
Sbjct: 206 IAEALEIPQVIIGLTVVAIGTSLPELVTSLVATFQGKTDIAVGNVVGSNIFNLLLVNGVC 265

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK--IYWHEALLLVLMYTFYILEKI 234
           +      + ++        MM       L +++   K  + W  A+LL  MY  Y + +I
Sbjct: 266 SSITQIAVPVNGGFYDL-FMMILLAVFLLPMSITHKKKIVRWEGAVLLA-MYLGYNVWRI 323



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 1/80 (1%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           +G  ++LV    + +   L V   + GLT++A GTS PE   ++L   QG+G +   N I
Sbjct: 16  LGGGNFLVTGA-SAMARNLGVSPLVIGLTVVAFGTSAPELSINLLGALQGNGGISFGNII 74

Query: 386 GSNTFDILLCLGLPWLVKSL 405
           GSN  +I L LGL  L++ L
Sbjct: 75  GSNIANIGLVLGLTALIRPL 94



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 88  ILLHCFLALYCF-LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           +L+  F+ ++   LLLG    ++ V     +   L ++  + G T +A  +S+PEL IN 
Sbjct: 1   MLIDSFMLVFGLTLLLGG--GNFLVTGASAMARNLGVSPLVIGLTVVAFGTSAPELSINL 58

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
           +G     G +  G ++GS + N+  V    AL     IE
Sbjct: 59  LGALQGNGGISFGNIIGSNIANIGLVLGLTALIRPLTIE 97


>UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Algoriphagus sp. PR1
          Length = 318

 Score = 60.9 bits (141), Expect = 6e-08
 Identities = 30/69 (43%), Positives = 44/69 (63%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           V+  +  V + I GLTI+AAGTSLPE  +SV+ + + +  + I N IGSN F+I L LG+
Sbjct: 196 VMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDIAIGNIIGSNIFNIFLILGV 255

Query: 399 PWLVKSLFY 407
             ++  L Y
Sbjct: 256 SSIINPLDY 264



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 6/94 (6%)

Query: 323 ITWIGSVSYLVA---WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           I  IG +  LV    W++   +V+  T  V D   GLTI+A GTS PE V + + +    
Sbjct: 6   ILLIGGLLLLVKGADWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHL 65

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPST 410
             +   N IGSN F++ + LG+  L+  L   S+
Sbjct: 66  PDLVFGNVIGSNNFNLFIILGIAGLIAPLSVQSS 99



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 6/118 (5%)

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           ++ +   ++  I G T +AA +S PEL  + V +     D+ +G ++GS +FN+  +   
Sbjct: 196 VMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDIAIGNIIGSNIFNIFLILGV 255

Query: 176 CALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK---IYWHEALLLVLMYTFYI 230
            ++      +L   S  +D  +       L L +   K   +   EA +L+L Y  YI
Sbjct: 256 SSIINPLDYQL---SFNKDLYILLGGTIFLFLAMFTGKRKSLDRWEAGILLLTYLVYI 310



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 20/73 (27%), Positives = 35/73 (47%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V    ++ +   ++    G T +A  +S+PEL +N + +     DL  G V+GS  F
Sbjct: 20  DWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHLPDLVFGNVIGSNNF 79

Query: 168 NVLAVPACCALFA 180
           N+  +     L A
Sbjct: 80  NLFIILGIAGLIA 92


>UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS
          Length = 253

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 5/100 (5%)

Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIIT---VVGDTLNVPDSITGLTILAAGTSLPEA 365
           RH H I  L FI  +  +G +     W++    V+     + + I  LT+++ GTSLPE 
Sbjct: 60  RHLHIILQLVFI--VAGLGLLVQGSNWLVNGAIVIAQFYGISELIIALTVISIGTSLPEL 117

Query: 366 VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            + ++ T +G   + + N +GSN F+ILL LGL  LV  +
Sbjct: 118 ATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPI 157



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 6/147 (4%)

Query: 90  LHCFLALYCFLL-LGSVCE--DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           LH  L L   +  LG + +  ++ V    +I +   I+  I   T ++  +S PEL    
Sbjct: 62  LHIILQLVFIVAGLGLLVQGSNWLVNGAIVIAQFYGISELIIALTVISIGTSLPELATVI 121

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
           +GTF  E +L VG VVGS +FN+L V     L +   I++   ++  D  +        +
Sbjct: 122 IGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVSQAAIFLDMPVMIAVAIACL 181

Query: 207 LTLLDDKI-YWHEALLLV--LMYTFYI 230
               ++ I  W   L L   + YT Y+
Sbjct: 182 PIFFNNLIERWEGGLFLAYYIAYTLYL 208


>UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 737

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 6/118 (5%)

Query: 290 FWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDS 349
           F  L W +   ++A +P C        +TF + + +IG ++ +V  + T+ G  + + + 
Sbjct: 625 FLTLAWKV---IFAAVPPCTWAGGW--VTFSVALCFIGILTAIVGDLATIFGCLVGLKNE 679

Query: 350 ITGLTILAAGTSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406
           +T  T +A GTSLP+   S      + +    I N  GSN+ ++ L LG PW++ +++
Sbjct: 680 VTAFTFVALGTSLPDLFASKAAAINEKYADACIGNVTGSNSVNVFLGLGTPWVIATIY 737



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 4/56 (7%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL 178
           +A  T MA  SS+PE+ ++ +   +  G     LG   +VGSA FN+L +   C +
Sbjct: 98  VANLTLMALGSSAPEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVM 153


>UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 837

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 33/109 (30%), Positives = 66/109 (60%), Gaps = 3/109 (2%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           +L+A IP  R     +P  F++ + +I +++ ++  +  ++G  +++ +S+TG+TI+A G
Sbjct: 651 VLFAFIPP-RPLLGGWP-AFVVSLLFIAALTAVIEQLGKLLGCVVDLRNSVTGITIIAIG 708

Query: 360 TSLPEAVSSVLVTKQGHGT-MGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           TSLP+ ++S     Q  G    I N  G N+ ++ L LGLPW++ + ++
Sbjct: 709 TSLPDTMASRSAALQDTGADAAIGNITGYNSVNVFLGLGLPWVMSTCYH 757



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 10/61 (16%)

Query: 127 IAGATFMAAASSSPELFINCVGT---------FVTEGDLGVGAVVGSAVFNVLAVPACCA 177
           +A  T MA  SS+PE+ +  V T           T+G LG   +VGSA FN+L + A C 
Sbjct: 95  VANLTLMALGSSAPEILLAVVETGQELALGQTTATDG-LGTFTIVGSASFNLLLITAVCV 153

Query: 178 L 178
           +
Sbjct: 154 V 154


>UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces
           cerevisiae YDL206w; n=1; Kluyveromyces lactis|Rep:
           Similar to sgd|S0002365 Saccharomyces cerevisiae YDL206w
           - Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 684

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 38/132 (28%), Positives = 73/132 (55%), Gaps = 6/132 (4%)

Query: 287 KKLFWVLTWPIRLIL---WATIPDCRHRHSIYPLTFIMCITWIGSVS--YLVAWIITVVG 341
           +KLF VLT+ + L +   +A + D   R+   PL+ + C   +G ++  YL   +  +  
Sbjct: 6   RKLF-VLTFYLGLTVIVGFAQLSDEVFRYVFSPLSLLTCFIALGIITSDYLTPNLTVISQ 64

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401
           + L + D I+G+T+LA G ++P+  S+    K+G  T+ I  S+G+  F + + +G   L
Sbjct: 65  ELLFISDRISGMTLLALGNAIPDITSTYKAMKRGTTTLAIGESLGAIFFLLTVVIGSMLL 124

Query: 402 VKSLFYPSTPEN 413
           V+++   + PE+
Sbjct: 125 VRNIKLSTPPES 136



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 26/80 (32%), Positives = 44/80 (55%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F++ I+ I  V  LV  I+T   +T N+ ++I GLT+ A G S+ + VS+V  T+ G   
Sbjct: 524 FVLSISSISFVVGLVLDILTNWAETFNLSEAILGLTVFAWGNSIGDLVSNVTFTRIGVLE 583

Query: 379 MGISNSIGSNTFDILLCLGL 398
           + + +  GS     L  +G+
Sbjct: 584 IALGSCFGSPLLYFLFGVGV 603



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 2/78 (2%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASD-IAGATFMAAASSSPELFINCVGTFVTEG 154
           L CF+ LG +  DY  P + +I + L   SD I+G T +A  ++ P++            
Sbjct: 41  LTCFIALGIITSDYLTPNLTVISQELLFISDRISGMTLLALGNAIPDITSTYKAMKRGTT 100

Query: 155 DLGVGAVVGSAVFNVLAV 172
            L +G  +G A+F +L V
Sbjct: 101 TLAIGESLG-AIFFLLTV 117


>UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida
           albicans IPF11817 unknown function; n=1; Debaryomyces
           hansenii|Rep: Similar to CA1231|IPF11817 Candida
           albicans IPF11817 unknown function - Debaryomyces
           hansenii (Yeast) (Torulaspora hansenii)
          Length = 710

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 39/181 (21%), Positives = 81/181 (44%), Gaps = 4/181 (2%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           LL C   L  F+ LG    DY  P +  I + L ++ ++AG T +A  + SP++      
Sbjct: 86  LLSCLSLL--FIALGMTASDYLCPNLYTISKFLELSDNLAGLTLLAFGNGSPDVLSTYKA 143

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208
             +  G L +  ++G+A+F +  +    A+     +  D +   RD   +      ++++
Sbjct: 144 MSLDSGSLAISELMGAALFIITVIVGSMAVVHPFKVPRDLF--IRDAGFFLGVIALVLIS 201

Query: 209 LLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGS 268
           LL+  +     +LL+ +Y  Y++  +      +    R V+         +TR  D++G+
Sbjct: 202 LLNSYLSMVNCILLIGVYVIYVVIVVLNHSFLKSKIRRRVREERSRGNYSLTRPQDNSGT 261

Query: 269 D 269
           +
Sbjct: 262 E 262



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 18/68 (26%), Positives = 32/68 (47%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F + I+WI   +  +  I+  V    ++ D I G+T+ A G S+ + +S+  + K G   
Sbjct: 557 FAIAISWISIFATEIISILKTVSIIYDLSDDILGITVFALGNSIGDFISNFTIAKMGMPL 616

Query: 379 MGISNSIG 386
           M      G
Sbjct: 617 MAFGACFG 624


>UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1060

 Score = 60.5 bits (140), Expect = 8e-08
 Identities = 28/90 (31%), Positives = 50/90 (55%)

Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           +HR  +  + F++ I WI +++  V  ++   G  L + D+I GLTI A G SL + V+ 
Sbjct: 872 KHRFVLCFVGFVVAIAWISTIANEVVGVLKAFGVILGISDAILGLTIFAVGNSLGDLVAD 931

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + V + G+  M +S   G    +IL+ +G+
Sbjct: 932 ITVARLGYPVMALSACFGGPMLNILIGIGV 961



 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 3/145 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F +L  +L L  F  +G    D+F   +  I   L ++  +AG TF+A  + SP++F   
Sbjct: 119 FAILILWLGLL-FSTIGIAASDFFCINLSTIASILGMSESMAGVTFLAFGNGSPDVFSTF 177

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                  G L VG ++G+A F    V    AL      ++   +  RD   +       +
Sbjct: 178 AAMSSHSGSLAVGELIGAAGFITAVVAGSMALV--REFKVGKKTFVRDIGFFIVAASFSM 235

Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231
           + L D  ++  E  +++  Y FY++
Sbjct: 236 VFLADGALHLWECFVMIGFYLFYVV 260



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367
           PL F + I W+G        + S      ++ +   L + +S+ G+T LA G   P+  S
Sbjct: 116 PLAFAILILWLGLLFSTIGIAASDFFCINLSTIASILGMSESMAGVTFLAFGNGSPDVFS 175

Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           +        G++ +   IG+  F   +  G   LV+
Sbjct: 176 TFAAMSSHSGSLAVGELIGAAGFITAVVAGSMALVR 211


>UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sodium/calcium
           exchanger - Lentisphaera araneosa HTCC2155
          Length = 319

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 25/62 (40%), Positives = 43/62 (69%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L V  ++ GLTI+A GTSLPE  +S++ + +GHG M + N IGS  F++L  +G+  +++
Sbjct: 201 LGVSQAVIGLTIVALGTSLPELAASIMASLKGHGDMALGNVIGSCIFNLLAIMGITSMIE 260

Query: 404 SL 405
           ++
Sbjct: 261 TI 262



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 4/83 (4%)

Query: 94  LALYCFLLLGSVCEDY----FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149
           LAL+  +  G     Y    FV     I   L ++  + G T +A  +S PEL  + + +
Sbjct: 170 LALFGLIFAGLAGVTYGGSIFVDGASTIAAGLGVSQAVIGLTIVALGTSLPELAASIMAS 229

Query: 150 FVTEGDLGVGAVVGSAVFNVLAV 172
               GD+ +G V+GS +FN+LA+
Sbjct: 230 LKGHGDMALGNVIGSCIFNLLAI 252



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 21/56 (37%), Positives = 31/56 (55%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           + GLT++A GTS PE    +  T  G   + + N IGSN  +I L L +  L+K +
Sbjct: 39  VVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNICNIGLVLAIAALLKPI 94



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 2/123 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V     +  R  ++  + G T +A  +S+PEL +    T     D+ +G V+GS + 
Sbjct: 20  DWLVDGAVGLSLRWGMSPLVVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNIC 79

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  V A  AL     ++     +  D  +         L + D ++ +   ++L  M  
Sbjct: 80  NIGLVLAIAALLKPIAVQSQLIKI--DVPVSIIAALAFFLQIQDGQLDFSNGIILFAMVV 137

Query: 228 FYI 230
            Y+
Sbjct: 138 CYV 140


>UniRef50_Q2HE40 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 221

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)

Query: 289 LFWVLTWPIRL--ILWATIPDCRHRHSIYP--LTFIMCITWIGSVSYLVAWIITVVGDTL 344
           L+ +LT  I L  +L  T P  + R+      L FI+ + WI +++  V  ++  +G  L
Sbjct: 3   LYTLLTSLILLAALLATTTPHKKPRYHFLLCFLGFIISVAWISTIAGEVVGVLKALGVIL 62

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
            + ++I GLT+ A G SL + V+ V V + G+  M ++ S+G    +ILL +G+
Sbjct: 63  GISEAILGLTVFAVGNSLGDLVADVTVARLGYPVMALAASVGGPMLNILLGVGI 116


>UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 1013

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 3/145 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F+++  +L+L  F  +G    D+    +  I   L ++  + G TF+A  + SP++F   
Sbjct: 118 FVIIALWLSLL-FSTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFSTF 176

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                  G L +G ++G+A F    V    AL       +   S  RD   +       +
Sbjct: 177 AAMSSNSGSLAIGELIGAAGFISAVVAGSMALV--RPFRVARRSFVRDIAFFTCAATVSL 234

Query: 207 LTLLDDKIYWHEALLLVLMYTFYIL 231
           + + D K+Y  E +L++  Y FY++
Sbjct: 235 VFIADGKLYIWECVLMIGFYIFYVV 259



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 33/105 (31%), Positives = 58/105 (55%), Gaps = 1/105 (0%)

Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           R R  +  L F++ I WI +++  V  ++  +G  L++ DS+ GLT+ A G SL + V+ 
Sbjct: 827 RARPFVAFLGFLVSIAWISTLATEVVNVLKSIGVILSISDSLLGLTVFAVGNSLGDLVAD 886

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413
           V V + G+  M +S   G    +IL+ +G+  L  +L  P+ P +
Sbjct: 887 VTVARLGYPVMALSACFGGPMLNILIGIGVGGLYMTL-SPNQPSS 930



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 316 PLTFIMCITWIG--------SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367
           PL F++   W+         + S  +   ++ +   L + +S+TG+T LA G   P+  S
Sbjct: 115 PLAFVIIALWLSLLFSTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFS 174

Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           +        G++ I   IG+  F   +  G   LV+
Sbjct: 175 TFAAMSSNSGSLAIGELIGAAGFISAVVAGSMALVR 210


>UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 996

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 3/144 (2%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F+++  +LA+  F  +G    D+F   +  I   L ++  +AG T +A  + SP++F   
Sbjct: 109 FVIMTLWLAML-FSTIGIAASDFFCVNLNTIARMLGMSESLAGVTLLAFGNGSPDVFSTF 167

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                    L VG ++G+A F    V    AL     +     S  RD   +       +
Sbjct: 168 AAFRTHAASLAVGELIGAACFITAVVSGSMALIRPFAVARK--SFIRDVGFFLVAAAFSM 225

Query: 207 LTLLDDKIYWHEALLLVLMYTFYI 230
             ++D K++  E+L +V  Y FY+
Sbjct: 226 GFIIDGKLHLWESLAMVAFYIFYV 249



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 29/80 (36%), Positives = 45/80 (56%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F + I WI +++  V  ++  +G  LN+ D+I GLTI A G SL + V+ + V + G   
Sbjct: 825 FAVAIAWISTIANEVVGVLRTLGVILNMSDAILGLTIFAVGNSLGDLVADITVARLGFPI 884

Query: 379 MGISNSIGSNTFDILLCLGL 398
           M +S   G    +ILL +GL
Sbjct: 885 MALSACFGGPMLNILLGIGL 904


>UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=4; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Desulfovibrio desulfuricans (strain G20)
          Length = 322

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 27/69 (39%), Positives = 41/69 (59%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S ++ W    +     V D I GLTI+A GTSLPE  SS++ T++G   + + N +GSN 
Sbjct: 188 SRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALGNVLGSNL 247

Query: 390 FDILLCLGL 398
           F+ L  +G+
Sbjct: 248 FNTLAVVGI 256



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 22/60 (36%), Positives = 34/60 (56%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +P  + G+ I+  GTS PE V S L   QG+  + + N+ GSN  +I L LG+  L+  +
Sbjct: 35  MPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITNIALILGVTALISPI 94



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 1/60 (1%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           A+EI      ++  I G T +A  +S PEL  + + T   E D+ +G V+GS +FN LAV
Sbjct: 195 AVEI-AHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKGEHDIALGNVLGSNLFNTLAV 253


>UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 305

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 6/142 (4%)

Query: 97  YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           Y  L++G V      D+FV     +   L I S I G T +A  +S+PE  ++       
Sbjct: 3   YLLLIIGFVLLIKGADFFVEGSSSLARFLKIPSVIIGLTIVAMGTSAPEASVSINAALAG 62

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
             D+ V  ++GS +FN L V   CA  +G     D   + RD  +       L + + + 
Sbjct: 63  NNDIAVSNIIGSNIFNGLIVVGICAFISGFKTNKD--ILKRDMPVNILITVILCIMIANG 120

Query: 213 KIYWHEALLLVLMYTFYILEKI 234
           K+   E +LL+    FYIL  I
Sbjct: 121 KLSRIEGILLLAGMIFYILNMI 142



 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 27/63 (42%), Positives = 41/63 (65%)

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           +  V  +  GLTI+A GTSLPE V+S++ T++G   + + N+IGSN F+IL  LG+   +
Sbjct: 191 SFGVSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFNILFILGMSATI 250

Query: 403 KSL 405
             L
Sbjct: 251 SPL 253



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV- 402
           L +P  I GLTI+A GTS PEA  S+     G+  + +SN IGSN F+ L+ +G+   + 
Sbjct: 31  LKIPSVIIGLTIVAMGTSAPEASVSINAALAGNNDIAVSNIIGSNIFNGLIVVGICAFIS 90

Query: 403 -----KSLFYPSTPENHWVTDLYFIRINNG 427
                K +     P N  +T +  I I NG
Sbjct: 91  GFKTNKDILKRDMPVNILITVILCIMIANG 120



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 17/56 (30%), Positives = 29/56 (51%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I     ++ +  G T +A  +S PEL  + V T   +  L +G  +GS +FN+L +
Sbjct: 188 IAVSFGVSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFNILFI 243


>UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1;
           Schizosaccharomyces pombe|Rep: Sodium/calcium exchanger
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 743

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 26/87 (29%), Positives = 49/87 (56%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F++ I WI +++  V  I+  +G   N+ +SI GLT+ AAG SL + ++ +++ + G   
Sbjct: 589 FVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPE 648

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405
           M +    G  T +IL+ +G+     S+
Sbjct: 649 MAMGGVFGGPTLNILIGIGISSFYSSI 675



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 3/137 (2%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155
           ++ F+ +G    D+F   +  I   L +   + G TF+A  + SP++        V  G 
Sbjct: 120 IFLFITIGISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNSGG 179

Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLL-DDKI 214
           + +G ++GSA F V  V     L      ++      RD          +I+ +L D  +
Sbjct: 180 MAIGELLGSAFFIVAIVAGSVCLI--KPFKIPRRHFLRDVAFLTGTILLVIMFVLHDGSL 237

Query: 215 YWHEALLLVLMYTFYIL 231
              ++L+++L Y  Y+L
Sbjct: 238 SIWQSLVMILYYLLYVL 254



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 4/106 (3%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F+     I +  +    ++T+    L +PDS+ G+T LA G   P+ +S+    +   
Sbjct: 119 LIFLFITIGISASDFFSTNLVTISW-LLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNS 177

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFI 422
           G M I   +GS  F + +  G   L+K       P  H++ D+ F+
Sbjct: 178 GGMAIGELLGSAFFIVAIVAGSVCLIKPF---KIPRRHFLRDVAFL 220


>UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Gammaproteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
           17024)
          Length = 331

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 26/73 (35%), Positives = 43/73 (58%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S ++ W      +  +V   I GLT++A GTSLPE  +SV+   +GH  + + N IGSN 
Sbjct: 193 SEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHDIALGNIIGSNI 252

Query: 390 FDILLCLGLPWLV 402
           F++L  + +P ++
Sbjct: 253 FNLLAVMAVPGII 265



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 26/88 (29%), Positives = 45/88 (51%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +  +  V   + GLTI++ GTS PE + S+  + +  G + I N++GSN  +I L LG  
Sbjct: 36  IAKSFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIANIGLVLGAT 95

Query: 400 WLVKSLFYPSTPENHWVTDLYFIRINNG 427
            L+ ++        H +  L  + I +G
Sbjct: 96  LLIAAIPVQKHIFRHELPVLLLVTIISG 123



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 21/81 (25%), Positives = 41/81 (50%)

Query: 105 VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGS 164
           +  +  V   +   E  +++  I G T +A  +S PEL  + +       D+ +G ++GS
Sbjct: 191 ISSEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHDIALGNIIGS 250

Query: 165 AVFNVLAVPACCALFAGAVIE 185
            +FN+LAV A   + +  ++E
Sbjct: 251 NIFNLLAVMAVPGIISPPIME 271



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 20/78 (25%), Positives = 37/78 (47%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV     I +   +A  + G T ++  +S+PE+ ++   +    GDL +G  +GS + 
Sbjct: 27  DRFVAGSAAIAKSFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIA 86

Query: 168 NVLAVPACCALFAGAVIE 185
           N+  V     L A   ++
Sbjct: 87  NIGLVLGATLLIAAIPVQ 104


>UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma
           proteobacterium HTCC2207|Rep: Putative Ca2+/Na+
           antiporter - gamma proteobacterium HTCC2207
          Length = 330

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 47/80 (58%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L FI+ +  + + + +  W    +  +L + + I GLT++A GTSLPE  +SV+   +GH
Sbjct: 175 LWFIVGLAVLLASAEVTVWSAKTIAQSLGISELIIGLTVVAIGTSLPELAASVVSAMRGH 234

Query: 377 GTMGISNSIGSNTFDILLCL 396
             + I N  GSN F+++L +
Sbjct: 235 HDIAIGNVFGSNLFNLMLVM 254



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409
           I GLT+++ GTS PE + S+         + + N++GSN  +I L LG   L+     P+
Sbjct: 42  IIGLTVVSIGTSAPEVLVSINAALSNAAELAVGNALGSNMANIGLVLGATLLIA----PT 97

Query: 410 TPENHWVT 417
             + H +T
Sbjct: 98  PVQKHLLT 105



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 21/68 (30%), Positives = 33/68 (48%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I + L I+  I G T +A  +S PEL  + V       D+ +G V GS +FN++ V    
Sbjct: 198 IAQSLGISELIIGLTVVAIGTSLPELAASVVSAMRGHHDIAIGNVFGSNLFNLMLVMPAA 257

Query: 177 ALFAGAVI 184
            + +   I
Sbjct: 258 GIISPMTI 265


>UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 336

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 6/109 (5%)

Query: 87  FILLHCFLAL-YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           F L+  FL + + FL+ G+   D+FV     I ++L + S I G T +A  +S PE  ++
Sbjct: 10  FALVIMFLIIGFVFLIKGA---DFFVEGSSSIAKKLKVPSIIIGLTIVAMGTSLPETAVS 66

Query: 146 CVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRD 194
              + V   +L V  VVGS +FN++ V   CA+    +++ D  ++ RD
Sbjct: 67  VTASLVHNNELAVSNVVGSNIFNLMFVIGVCAIMTPIMVQKD--TIVRD 113



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 7/89 (7%)

Query: 315 YPLTFIMCITWIGSVSYLVAWIITV-----VGDTLNVPDSITGLTILAAGTSLPEAVSSV 369
           YP + I+CI   G+V+      +TV     +   L +  ++ GLTI++ GTSLPE V+SV
Sbjct: 191 YPKS-ILCIVG-GAVAIAFGGDMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSV 248

Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +  ++    M + N++GSN F+IL+ LG+
Sbjct: 249 VAARKNEVDMAVGNAVGSNIFNILMVLGI 277



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 24/59 (40%), Positives = 36/59 (61%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +   L VP  I GLTI+A GTSLPE   SV  +   +  + +SN +GSN F+++  +G+
Sbjct: 38  IAKKLKVPSIIIGLTIVAMGTSLPETAVSVTASLVHNNELAVSNVVGSNIFNLMFVIGV 96



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 2/122 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D  V A   I   L ++  + G T ++  +S PEL  + V     E D+ VG  VGS +F
Sbjct: 210 DMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIF 269

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+L V    +  A + + L   +V    ++             D KI  +E + +V MY 
Sbjct: 270 NILMVLGIAS--AISPMSLISENVIDILVLVGFSVVVWFFARSDRKITRNEGIAMVAMYL 327

Query: 228 FY 229
            Y
Sbjct: 328 IY 329


>UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 386

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 30/101 (29%), Positives = 61/101 (60%), Gaps = 3/101 (2%)

Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364
           IP     HS++ +  ++ ++  G   Y+++  +T +  +L++  ++ G TIL+  T+LPE
Sbjct: 235 IPRSTLYHSVHLILGLLALSLSG---YILSHSLTSLATSLSLSTNVLGTTILSIATTLPE 291

Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            + ++L  K+  G + ++N++GSNTF + LC G+ +L   L
Sbjct: 292 KLVAILSGKRRQGGIIVANTVGSNTFLLTLCAGILFLAGDL 332


>UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep: Ca2+/Na+
           antiporter - Methanobrevibacter smithii (strain PS /
           ATCC 35061 / DSM 861)
          Length = 313

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 30/66 (45%), Positives = 41/66 (62%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +   L +P  I GLTI+A GTS PEA  S+  + QG   + +SN IGSN F+IL  +G+ 
Sbjct: 32  IATILKIPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNALAVSNVIGSNIFNILGIIGIC 91

Query: 400 WLVKSL 405
            L+K L
Sbjct: 92  ALLKEL 97



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 26/51 (50%), Positives = 35/51 (68%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +++ GLTI+A GTSLPE V+S+   K+    + I N IGSN F+IL  LGL
Sbjct: 203 ETLVGLTIVAIGTSLPELVTSLTALKRDENQLVIGNVIGSNIFNILFVLGL 253



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 97  YCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156
           +  L+ GS   D FV     I   L I + I G T +A  +S+PE  ++   +      L
Sbjct: 15  FAILIKGS---DIFVSGSSNIATILKIPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNAL 71

Query: 157 GVGAVVGSAVFNVLAVPACCAL 178
            V  V+GS +FN+L +   CAL
Sbjct: 72  AVSNVIGSNIFNILGIIGICAL 93



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 17/50 (34%), Positives = 27/50 (54%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           ++  + G T +A  +S PEL  +       E  L +G V+GS +FN+L V
Sbjct: 201 MSETLVGLTIVAIGTSLPELVTSLTALKRDENQLVIGNVIGSNIFNILFV 250


>UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 1
           precursor (Na(+)/Ca(2+)-exchange protein 1). - Takifugu
           rubripes
          Length = 900

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 27/90 (30%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           FI+CI+ IG ++ ++  I +  G T+ + DS+T +  +A GTS+P+   S V   +  + 
Sbjct: 731 FIVCISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 790

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
              I N  GSN  ++ L +G+ W + ++++
Sbjct: 791 DASIGNVTGSNAVNVFLGIGVAWSIAAIYH 820



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ++  T MA  SS+PE+ ++ V   G     G+LG   +VGSA FN+  +   C
Sbjct: 121 VSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLC 173



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 5/55 (9%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
           ++++ LT++A G+S PE + SV V   GH    G +G +  +GS  F++ + +GL
Sbjct: 119 ETVSNLTLMALGSSAPEILLSV-VEVCGHNFDAGELGPNTIVGSAAFNMFVIIGL 172


>UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family
           precursor - Psychrobacter sp. PRwf-1
          Length = 322

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 30/88 (34%), Positives = 50/88 (56%)

Query: 318 TFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHG 377
           T I+ ++ + + S  + W    +     + + + GLTI+A GTSLPE V+SV   ++G  
Sbjct: 175 TLILGLSLLIASSRAIVWGAVELATLWGMSELLIGLTIVAIGTSLPELVASVAAARRGEH 234

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSL 405
            M + N IGSN F+ L  +GL  ++K +
Sbjct: 235 DMALGNVIGSNLFNTLGVVGLAAIIKPM 262



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 2/127 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D F+     +  R N+ S + G   +   +S+PEL ++ +  F    DL +G   GS + 
Sbjct: 20  DTFIDGATSLAVRFNMPSFLIGVIILGIGTSAPELVVSALAAFAGSPDLALGNAYGSNII 79

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  V    AL +  +I  D   +  D M+         + L+D  +   + ++LV+   
Sbjct: 80  NITLVLGVTALISPILIRSD--VIRYDLMLLLAVTALAAIQLVDGNLSRLDGIVLVVALV 137

Query: 228 FYILEKI 234
             +L +I
Sbjct: 138 AVLLIQI 144



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 24/65 (36%), Positives = 34/65 (52%)

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           N+P  + G+ IL  GTS PE V S L    G   + + N+ GSN  +I L LG+  L+  
Sbjct: 34  NMPSFLIGVIILGIGTSAPELVVSALAAFAGSPDLALGNAYGSNIINITLVLGVTALISP 93

Query: 405 LFYPS 409
           +   S
Sbjct: 94  ILIRS 98



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186
           + G T +A  +S PEL  +       E D+ +G V+GS +FN L V    A+    +  +
Sbjct: 207 LIGLTIVAIGTSLPELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIK-PMQHI 265

Query: 187 DWWSVTRDCMMYXXXXXXL-ILTLL----DDKIYWHEALLLVLMYTFY 229
           D   ++RD MM       L IL ++      ++     ++L+L + FY
Sbjct: 266 DPQILSRDVMMVGMVSVLLFILAIIAFKRQGEMKHGSGVVLILTFIFY 313


>UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=3; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Stappia aggregata
           IAM 12614
          Length = 337

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 27/63 (42%), Positives = 40/63 (63%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +   L +P+ + GLTI+A GTS PE V S+    +G G + I N +GSN  ++LL LG+P
Sbjct: 29  IAQRLGIPNLVIGLTIVAFGTSAPELVISLKAALEGAGGIAIGNVVGSNIANVLLVLGMP 88

Query: 400 WLV 402
            L+
Sbjct: 89  ALI 91



 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 25/71 (35%), Positives = 44/71 (61%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +  +  V +++ GLT++A GTSLPE  ++V+   + HG + I N IGSN F++L  +G
Sbjct: 213 TSIATSWGVSEAVIGLTVIALGTSLPELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIG 272

Query: 398 LPWLVKSLFYP 408
           +  ++  +  P
Sbjct: 273 ITAVIVPIDVP 283



 Score = 46.4 bits (105), Expect = 0.001
 Identities = 30/92 (32%), Positives = 47/92 (51%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +L  +++L   L++  +  D  V     I +RL I + + G T +A  +S+PEL I+   
Sbjct: 1   MLFDYISLAGGLVVLIIAGDVLVRGSVGIAQRLGIPNLVIGLTIVAFGTSAPELVISLKA 60

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
                G + +G VVGS + NVL V    AL A
Sbjct: 61  ALEGAGGIAIGNVVGSNIANVLLVLGMPALIA 92



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 5/72 (6%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA-- 180
           ++  + G T +A  +S PEL    +      G + +G V+GS VFN+LA+    A+    
Sbjct: 221 VSEAVIGLTVIALGTSLPELATTVMAAIRQHGAVAIGNVIGSNVFNLLAIIGITAVIVPI 280

Query: 181 ---GAVIELDWW 189
                V++LD W
Sbjct: 281 DVPQEVLKLDIW 292


>UniRef50_Q21609 Cluster: Sodium-calcium exchanger; n=3;
           Caenorhabditis|Rep: Sodium-calcium exchanger -
           Caenorhabditis elegans
          Length = 880

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 36/122 (29%), Positives = 64/122 (52%), Gaps = 4/122 (3%)

Query: 282 KISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVG 341
           +++  +K+   +  P +L L+A IP   + +    L F++ I  IG ++  +  I    G
Sbjct: 676 EVTTMEKVMHYIALPWKL-LFALIPPTDYFNGW--LCFVVAIAMIGLLTAFIGDIAAAFG 732

Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG-ISNSIGSNTFDILLCLGLPW 400
            T+ + DS+T LT++A GTSLP+  +S           G I N  GSN  ++ L +G+ W
Sbjct: 733 CTVGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAW 792

Query: 401 LV 402
           ++
Sbjct: 793 MI 794



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           ++  T MA  SS+PE+ ++ +   G     G+LG   +VGSA FN+  + A C +
Sbjct: 130 VSNLTLMALGSSAPEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVCIM 184


>UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23;
           Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio
           vulnificus
          Length = 321

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 26/68 (38%), Positives = 40/68 (58%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           ++     + D + GLTI+A GTSLPE  +S+    +G   M + N IGSN F+IL  +G+
Sbjct: 198 IIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVGNIIGSNVFNILAVMGI 257

Query: 399 PWLVKSLF 406
           P ++   F
Sbjct: 258 PGILNPSF 265



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 39/73 (53%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           L+L  +  D  V    II +   ++  + G T +A  +S PEL  +  G    E D+ VG
Sbjct: 182 LILLPLAADMLVDNAVIIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVG 241

Query: 160 AVVGSAVFNVLAV 172
            ++GS VFN+LAV
Sbjct: 242 NIIGSNVFNILAV 254



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 2/143 (1%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +L     L   L+L     D  V     +   + I+  + G T +A  SS+PE+ ++   
Sbjct: 1   MLEAVALLIVGLILLVWSADKLVFGSAALARNIGISPLVIGMTILAMGSSAPEMMVSATA 60

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208
               + D  VG V+GS + N+  +    AL     + ++   V R+  +         + 
Sbjct: 61  ALDGKTDTAVGNVLGSNIANIALILGITALV--RPLSINSAVVRRELPLMIGVTILAGIL 118

Query: 209 LLDDKIYWHEALLLVLMYTFYIL 231
           L D  + ++E +LL +++T +++
Sbjct: 119 LWDSHLGFYEGVLLFVLFTLFLV 141



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 22/62 (35%), Positives = 33/62 (53%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + +   + G+TILA G+S PE + S      G     + N +GSN  +I L LG+  LV+
Sbjct: 33  IGISPLVIGMTILAMGSSAPEMMVSATAALDGKTDTAVGNVLGSNIANIALILGITALVR 92

Query: 404 SL 405
            L
Sbjct: 93  PL 94


>UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Halothermothrix orenii H 168|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Halothermothrix orenii H 168
          Length = 383

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 4/135 (2%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
           FL++GS      +PA+EI   R+ I   I  AT +A  +S PEL           G+L V
Sbjct: 245 FLVIGS--SKVLIPAVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAV 302

Query: 159 GAVVGSAVFNVL-AVPACCALFAGAV-IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYW 216
           G +VG+ + NVL  V +  ++ AG + +  +++ +    M+       L     +++I  
Sbjct: 303 GNIVGADILNVLFVVGSAASVTAGGLNVPANFYRLQIPTMVIILVTFRLFSRGRNEEITK 362

Query: 217 HEALLLVLMYTFYIL 231
            E ++L L+Y  Y++
Sbjct: 363 KEGIVLFLLYVIYLI 377



 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 22/72 (30%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           IGS   L+   + +    + +P+SI   T++A GTSLPE ++++   ++GHG + + N +
Sbjct: 248 IGSSKVLIP-AVEITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAVGNIV 306

Query: 386 GSNTFDILLCLG 397
           G++  ++L  +G
Sbjct: 307 GADILNVLFVVG 318



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 26/62 (41%), Positives = 37/62 (59%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L VP  I G TI++ GT+LPEA  SVL    G+  + + N++GS   D  L +G+  L+ 
Sbjct: 73  LGVPKVIIGATIVSLGTTLPEAAVSVLAAINGNPDLALGNAVGSIIADTGLIIGVAALLG 132

Query: 404 SL 405
           SL
Sbjct: 133 SL 134


>UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Marinobacter sp. ELB17|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Marinobacter sp. ELB17
          Length = 328

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 27/65 (41%), Positives = 41/65 (63%)

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
           G  L VP+++ G+T++A GTSLPE  +SV   ++G   M I   +GSN F+IL  + +  
Sbjct: 200 GFALGVPEAVIGMTVIAFGTSLPELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITA 259

Query: 401 LVKSL 405
           +VK L
Sbjct: 260 VVKPL 264



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 21/65 (32%), Positives = 35/65 (53%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L +   + G T +A  +S PEL  +       + D+ +G +VGS +FN+L+V A  A+  
Sbjct: 203 LGVPEAVIGMTVIAFGTSLPELTASVAAARKGQSDMIIGGIVGSNIFNILSVMAITAVVK 262

Query: 181 GAVIE 185
             VI+
Sbjct: 263 PLVID 267



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 5/110 (4%)

Query: 76  DGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAA 135
           DGLT +Q     I L         L+ G    D  + +   I ER  ++     AT +A 
Sbjct: 2   DGLTTYQL--AVIALGAIFFGVWLLVKGG---DLTIDSAVRIAERSGLSKMFIAATIVAF 56

Query: 136 ASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
            +S+PELF +          + VG V+GS + NVL V    A+ A  V +
Sbjct: 57  GTSAPELFTSVNANISGFAGISVGNVIGSNIANVLMVIGISAMIAPIVFD 106



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 18/54 (33%), Positives = 31/54 (57%)

Query: 354 TILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           TI+A GTS PE  +SV     G   + + N IGSN  ++L+ +G+  ++  + +
Sbjct: 52  TIVAFGTSAPELFTSVNANISGFAGISVGNVIGSNIANVLMVIGISAMIAPIVF 105


>UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3;
           Caenorhabditis|Rep: Na/ca exchangers protein 8 -
           Caenorhabditis elegans
          Length = 703

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 27/95 (28%), Positives = 53/95 (55%)

Query: 310 HRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369
           H+     L F+M I WI + +  +  ++T+VG    +   + GLT+++    + + V+ +
Sbjct: 540 HKEVYSYLGFLMSIAWIYATANEIISVMTMVGVVTGLSQELLGLTVMSWSDCIGDIVADI 599

Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            V KQG+  M ++ +IG   F++L+  GLP+ + S
Sbjct: 600 AVIKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIAS 634



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 8/152 (5%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELF---I 144
           I++     ++ F+++ ++ +D+F P+I  I   L ++  IAG TF+A  + +P++F    
Sbjct: 105 IIVGIIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSIS 164

Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204
           + + T   +  L +G + G+++F V  V     +F  +  ++      RD + Y      
Sbjct: 165 SVLSTPKPKAALALGDLFGTSIF-VTTVVLAIIIFTKS-FKVAIIPTLRDLIFYMITLAF 222

Query: 205 LILTLLD-DKI-YWHEALLLVLMYTFYILEKI 234
           +    L  DKI  W  A  L + Y  Y+L  I
Sbjct: 223 ITFCFLKFDKIEVWMPATFLGI-YAVYLLTVI 253


>UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2;
           Bacteria|Rep: Na+/Ca2+-exchanging protein - Salinibacter
           ruber (strain DSM 13855)
          Length = 350

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 24/62 (38%), Positives = 40/62 (64%)

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
           GD    P  + G+T++AAGTS+P+A  S+  ++ G+    ++N +GSN FD+L+C+    
Sbjct: 214 GDIFGTPSFLWGITVVAAGTSVPDAFVSIRASRAGNPVTSVANVLGSNIFDLLVCIPAAA 273

Query: 401 LV 402
           LV
Sbjct: 274 LV 275



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGD--LGVGAVVGSAVFNVLAVPACCALFAGAVI 184
           + G+  +A  SS PEL    V +    GD  LGV AVVGSA+FN+L +PA   L+A   +
Sbjct: 45  VQGSIVLAVGSSFPELS-TAVLSAALHGDFELGVAAVVGSALFNILMIPALAGLWAEERL 103

Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215
           E     + ++   Y      L+L      IY
Sbjct: 104 ESTRDLIYKETQFYLISIVVLLLMFSFAVIY 134



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLCLGLPWL 401
           +P  + G  +LA G+S PE  ++VL     G   +G++  +GS  F+IL+   L  L
Sbjct: 41  LPPLVQGSIVLAVGSSFPELSTAVLSAALHGDFELGVAAVVGSALFNILMIPALAGL 97


>UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein precursor; n=11; Proteobacteria|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein precursor
           - Azotobacter vinelandii AvOP
          Length = 360

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 9/93 (9%)

Query: 316 PLTFIMCITWIGSVSYLVAWIITVVGDT------LNVPDSITGLTILAAGTSLPEAVSSV 369
           PLTFI C+  I  ++ L+A    +V           +P  I GLT++A GTS PE   SV
Sbjct: 3   PLTFI-CL--IAGLALLIAGAEALVRGAARLAARFGIPPLIIGLTVVAFGTSAPEMAVSV 59

Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
                G G + + N+IGSN F++L+ LGL  LV
Sbjct: 60  RSASGGQGDIAVGNAIGSNIFNVLMILGLSALV 92



 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 49/154 (31%), Positives = 69/154 (44%), Gaps = 3/154 (1%)

Query: 79  TRFQRQ-HGFILLHCFLALYCFLLLGSVC-EDYFVPAIEIICERLNIASDIAGATFMAAA 136
           T F R+  G + L   LAL    L   V   D  + A   +   L ++    G T +AA 
Sbjct: 162 TEFGRKPEGRLALPGHLALVALGLAMLVWGSDLLIDATVTLARALGLSELAIGLTMVAAG 221

Query: 137 SSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDC- 195
           +S PEL  + V     E D+ VG +VGS +FN+LAV    AL + A IE+   ++  D  
Sbjct: 222 TSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALVSPAPIEVSPNALAFDYP 281

Query: 196 MMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
           +M       L + L   +I   E LL    Y  Y
Sbjct: 282 VMIAAAAACLPIFLTGYRIGRWEGLLFFGYYLAY 315



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 25/59 (42%), Positives = 38/59 (64%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L + +   GLT++AAGTSLPE  +S++   +G   + + N +GSN F++L  LGL  LV
Sbjct: 206 LGLSELAIGLTMVAAGTSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALV 264



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 3/87 (3%)

Query: 92  CFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV 151
           C +A    L+ G+   +  V     +  R  I   I G T +A  +S+PE+ ++      
Sbjct: 8   CLIAGLALLIAGA---EALVRGAARLAARFGIPPLIIGLTVVAFGTSAPEMAVSVRSASG 64

Query: 152 TEGDLGVGAVVGSAVFNVLAVPACCAL 178
            +GD+ VG  +GS +FNVL +    AL
Sbjct: 65  GQGDIAVGNAIGSNIFNVLMILGLSAL 91


>UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Reinekea sp. MED297|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Reinekea sp. MED297
          Length = 321

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 26/71 (36%), Positives = 41/71 (57%)

Query: 332 LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           ++ W    + D   + +++ G TI+A GTSLPE  +SV    + H  + I N +GSN F+
Sbjct: 188 VLVWGAVGIADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFN 247

Query: 392 ILLCLGLPWLV 402
           IL  L +P L+
Sbjct: 248 ILAVLSVPGLI 258



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 24/63 (38%), Positives = 39/63 (61%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + + L VP  I G+TI++ GTS PE ++++    +G   + + N+IGSN  +I L LG+ 
Sbjct: 29  LANNLGVPHLIIGVTIVSLGTSAPEIIAAIFAALEGRIELAMGNAIGSNVANIGLVLGIT 88

Query: 400 WLV 402
            LV
Sbjct: 89  ALV 91



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 22/71 (30%), Positives = 36/71 (50%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I +   I+  + GAT +A  +S PEL  +         D+ +G V+GS +FN+LAV +  
Sbjct: 196 IADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFNILAVLSVP 255

Query: 177 ALFAGAVIELD 187
            L A    + +
Sbjct: 256 GLIAPGAFDAE 266



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 23/87 (26%), Positives = 37/87 (42%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           LA+   L+   +  D FV     +   L +   I G T ++  +S+PE+           
Sbjct: 6   LAILVGLIFLVLSADRFVAGAAALANNLGVPHLIIGVTIVSLGTSAPEIIAAIFAALEGR 65

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFA 180
            +L +G  +GS V N+  V    AL A
Sbjct: 66  IELAMGNAIGSNVANIGLVLGITALVA 92


>UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Chloroflexus|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Chloroflexus
           aurantiacus J-10-fl
          Length = 361

 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 5/137 (3%)

Query: 93  FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           F+A    L+LG+   D  V     +   L ++S I G T +A  +SSPE+ ++    F  
Sbjct: 6   FIAGIVLLVLGA---DLLVRGAASLAAGLGVSSLIIGLTVVAVGTSSPEIAVSLQAAFDG 62

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
           +G + +G +VGS + NV+ +    A+F    + +D     RD  +         L  LD 
Sbjct: 63  QGAITLGNIVGSNIANVMLILGVAAMFGS--LPVDQQIFRRDLPIMIGASLLTFLLALDR 120

Query: 213 KIYWHEALLLVLMYTFY 229
            + W + ++++L  T Y
Sbjct: 121 TLSWVDGMIMLLALTGY 137



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 24/51 (47%), Positives = 33/51 (64%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           V + I GLTI+A GTSLPE  +SV+   +G   + + N IGSN  ++LL L
Sbjct: 198 VSELIIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLVL 248



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 24/62 (38%), Positives = 35/62 (56%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L V   I GLT++A GTS PE   S+     G G + + N +GSN  +++L LG+  +  
Sbjct: 31  LGVSSLIIGLTVVAVGTSSPEIAVSLQAAFDGQGAITLGNIVGSNIANVMLILGVAAMFG 90

Query: 404 SL 405
           SL
Sbjct: 91  SL 92



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 17/46 (36%), Positives = 26/46 (56%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I G T +A  +S PE+  + +     E D+ VG V+GS + N+L V
Sbjct: 202 IIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLV 247


>UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3;
           Flavobacteriales|Rep: Sodium/calcium exchanger -
           Robiginitalea biformata HTCC2501
          Length = 315

 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 6/98 (6%)

Query: 305 IPDCRHRHSIYPLTFIMCI----TWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGT 360
           +P  R    +Y +  ++ +     W GS   LV    ++  D L V D + G+T+++ GT
Sbjct: 158 LPVARRPLPLYKMALLLLVGGVALWAGS-ELLVRGATSLAAD-LGVSDRVIGITVVSVGT 215

Query: 361 SLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           S+PE  +SV+   +    M + N IGSN F++L  LGL
Sbjct: 216 SIPELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGL 253



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 6/114 (5%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L ++  + G T ++  +S PEL  + +     E  + VG ++GS +FN+LAV    A+ A
Sbjct: 199 LGVSDRVIGITVVSVGTSIPELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLTAILA 258

Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLL----DDKIYWHEALLLVLMYTFYI 230
              + LD   +TRD + +      L+L L+      ++ W + ++L+  Y  ++
Sbjct: 259 PVPV-LDDRLLTRD-VFWMLGISFLVLPLVFFPKGLRLGWRDGIVLLACYGAFL 310



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 18/59 (30%), Positives = 34/59 (57%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L++P  + G+T+++  TS PE + S      G+  + + N +GSNT ++ L L +  L+
Sbjct: 35  LSIPKIVIGMTVVSLATSAPELIVSAQAALAGYPDLALGNVVGSNTANLGLVLAVTLLI 93



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 21/59 (35%), Positives = 31/59 (52%)

Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           RL+I   + G T ++ A+S+PEL ++         DL +G VVGS   N+  V A   L
Sbjct: 34  RLSIPKIVIGMTVVSLATSAPELIVSAQAALAGYPDLALGNVVGSNTANLGLVLAVTLL 92


>UniRef50_Q59GN4 Cluster: Solute carrier family 8 (Sodium/calcium
           exchanger), member 1 variant; n=24; Bilateria|Rep:
           Solute carrier family 8 (Sodium/calcium exchanger),
           member 1 variant - Homo sapiens (Human)
          Length = 411

 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           FI+ I  IG ++  +  + +  G T+ + DS+T +  +A GTS+P+   S V  T+  + 
Sbjct: 242 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 301

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
              I N  GSN  ++ L +G+ W + ++++ +  E   V+
Sbjct: 302 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 341


>UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1); n=185;
           Euteleostomi|Rep: Sodium/calcium exchanger 1 precursor
           (Na(+)/Ca(2+)-exchange protein 1) - Homo sapiens (Human)
          Length = 973

 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           FI+ I  IG ++  +  + +  G T+ + DS+T +  +A GTS+P+   S V  T+  + 
Sbjct: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
              I N  GSN  ++ L +G+ W + ++++ +  E   V+
Sbjct: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 903



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ++  T MA  SS+PE+ ++ +   G   T GDLG   +VGSA FN+  + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186


>UniRef50_UPI0000498A17 Cluster: sodium/calcium exchanger protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: sodium/calcium
           exchanger protein - Entamoeba histolytica HM-1:IMSS
          Length = 510

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 1/104 (0%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F++ + +I   +  +  ++  +G  + +  SI GLT+L  G S+ + VS+V+V+ QG+  
Sbjct: 354 FVISVLYIYIFASELVALLQSIGVAMKIDSSILGLTVLCWGNSVGDFVSNVIVSSQGYSE 413

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKS-LFYPSTPENHWVTDLYF 421
           MGI  S G   F++L+ LG   L +S L +P + +      L+F
Sbjct: 414 MGIIASYGGPCFNLLIGLGGGVLARSILHFPKSQQIVMTDSLFF 457



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 53/241 (21%), Positives = 107/241 (44%), Gaps = 22/241 (9%)

Query: 87  FILLHCFLA--LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFI 144
           +I+L C +   +  F LL     D+FVP + I+ + L++++D+AG T +A  + +P++F 
Sbjct: 53  WIVLVCMVIGIIIIFYLLSVSSSDHFVPILTILSKHLSMSADLAGITILAIGNGAPDVFS 112

Query: 145 NCVGTFVT-EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXX 203
             V  + T + +L    V+GS  F    + A   L     I++   ++  +   Y     
Sbjct: 113 TFVAIYNTGDVELATAEVIGSGCFVSSIIVASIVLLGKEDIKMP-ETLIHNISCYILALL 171

Query: 204 XLILTLLDDKIYWHEALLLVLMYTFYI-----LEKINPL---------DASQRMTPRSVQ 249
            +        +    +++ +L+Y  Y+     + K  PL         +   ++   ++ 
Sbjct: 172 FVYFICTTGSVSIIHSIIFILIYILYVCFIGYITKNKPLIKISEQLDSENKTKLIDNTLN 231

Query: 250 NGD--LERGIEMTRRHDSTGSDISTSSVWSFPGD-KISFW-KKLFWVLTWPIRLILWATI 305
           N D  L    E T  +++  SD   +S ++     K++ W  K+  +L+ P R I+  T 
Sbjct: 232 NIDEELNSSNECTTLNNNISSDKGFTSQYNILEQIKLTNWFNKILLILSIPFRFIMEFTT 291

Query: 306 P 306
           P
Sbjct: 292 P 292


>UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family -
           Thermosipho melanesiensis BI429
          Length = 311

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 34/118 (28%), Positives = 63/118 (53%)

Query: 289 LFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
           L++++T    ++      + +++  I  L  ++ I  I     L    +  +  +L + +
Sbjct: 141 LYYLITSAKNVVEEEFKDEVKYKTHIALLLIVVGIVGIWLGGDLTIGNVIKLAKSLGLSE 200

Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406
           +  GLTI+A GTSLPE V S++ T +    + + N +GSN F+IL  LG+  LV +L+
Sbjct: 201 TFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVSSLVGNLY 258



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 3/117 (2%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + + L ++    G T +A  +S PE+ ++ + T   E D+ VG +VGS +FN+L +    
Sbjct: 192 LAKSLGLSETFVGLTIVAIGTSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVS 251

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILT-LLDDKIYWHEALLLVLMYTFYILE 232
           +L     +++   + T D ++       L  T LL  KI   E +  + +Y FYI +
Sbjct: 252 SLVGNLYVDVQ--NFTIDLIIMNLFVFILFFTSLLRKKIGKVEGIFFLTIYVFYIYQ 306



 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 3/74 (4%)

Query: 335 WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           W++   T +   L V   + GL+++A GTSLPE V+S++   +GH ++ ISN +GSN  +
Sbjct: 21  WLVDGATSIALNLGVSKIVVGLSVVAFGTSLPELVASLVSVIKGHSSVSISNVVGSNIAN 80

Query: 392 ILLCLGLPWLVKSL 405
           I + L L  L  S+
Sbjct: 81  IAIALALSSLFVSI 94



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 27/127 (21%), Positives = 56/127 (44%), Gaps = 4/127 (3%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V     I   L ++  + G + +A  +S PEL  + V        + +  VVGS + 
Sbjct: 20  DWLVDGATSIALNLGVSKIVVGLSVVAFGTSLPELVASLVSVIKGHSSVSISNVVGSNIA 79

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALL---LVL 224
           N+    A  +LF    I+ +        M+        +L + D+ + W+  ++   L++
Sbjct: 80  NIAIALALSSLFVSINIKKNTIKAEMPFMIISTIVFT-VLFIKDNSLTWNYGVVFISLLV 138

Query: 225 MYTFYIL 231
           +Y +Y++
Sbjct: 139 IYLYYLI 145


>UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter,
           CaCA family protein precursor - Psychromonas ingrahamii
           (strain 37)
          Length = 326

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 31/83 (37%), Positives = 46/83 (55%)

Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           I+ I  + + S L+ W    V     V D I GLTI+A GTSLPE  +++   ++    +
Sbjct: 180 IIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDL 239

Query: 380 GISNSIGSNTFDILLCLGLPWLV 402
            + N IGSN F+IL  + LP L+
Sbjct: 240 AVGNIIGSNIFNILGVMALPGLI 262



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 4/66 (6%)

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           + ++   I G+ I+  GTS PE + S +   QG+  + I N+IGSN  +I L LG    V
Sbjct: 35  SFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTGLSIGNAIGSNITNIGLMLG----V 90

Query: 403 KSLFYP 408
            ++FYP
Sbjct: 91  TAIFYP 96



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 20/48 (41%), Positives = 26/48 (54%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174
           I G T +A  +S PEL          E DL VG ++GS +FN+L V A
Sbjct: 210 IIGLTIVAIGTSLPELAATIAAARKKEFDLAVGNIIGSNIFNILGVMA 257


>UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Mycobacterium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 335

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 1/112 (0%)

Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364
           +PD       + +T +     +    +LV   + +  +   V D++ GLTI+A GTS PE
Sbjct: 179 MPDTGSLVRYFAMTIVGITVVVVGADWLVEGAVGIARE-FGVSDALIGLTIVAIGTSAPE 237

Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWV 416
            V++++ T +G   + I N +GS+ ++I+L LG   LV +   P      W+
Sbjct: 238 LVTTIVSTVRGERDIAIGNLLGSSVYNIVLILGATCLVPADGLPLNSSLVWI 289



 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 21/62 (33%), Positives = 36/62 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + +   + G+T+++ GTSLPE    V    +G G + + N  G+NT ++L  LGL  L++
Sbjct: 33  MGISPIVVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLSALLR 92

Query: 404 SL 405
            L
Sbjct: 93  PL 94



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 1/124 (0%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V     I     ++  + G T +A  +S+PEL    V T   E D+ +G ++GS+V+
Sbjct: 204 DWLVEGAVGIAREFGVSDALIGLTIVAIGTSAPELVTTIVSTVRGERDIAIGNLLGSSVY 263

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD-KIYWHEALLLVLMY 226
           N++ +     L     + L+   V  D  +       LI       +++  E   +V+ Y
Sbjct: 264 NIVLILGATCLVPADGLPLNSSLVWIDIPVMVVATLLLIPVFFSGRRVHRAEGGAMVVAY 323

Query: 227 TFYI 230
             Y+
Sbjct: 324 LAYL 327



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 18/69 (26%), Positives = 31/69 (44%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           +  R+ I+  + G T ++  +S PEL +         G L VG + G+   N+L +    
Sbjct: 29  MASRMGISPIVVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLS 88

Query: 177 ALFAGAVIE 185
           AL     I+
Sbjct: 89  ALLRPLAIQ 97


>UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 974

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 6/146 (4%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           FIL   F+  + F  +G    D+F P +  +   L +    AG TF+A  + SP++F   
Sbjct: 78  FILFLLFILAFLFSFIGISAADFFCPNLSTVAAYLGLNESTAGVTFLAFGNGSPDVF--S 135

Query: 147 VGTFVTEGDLG--VGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXX 204
             + ++ G LG  VG ++G+A F V  V    A      +  +  +  RD + +      
Sbjct: 136 TFSAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIRPFHVPKN--AFRRDVIFFTIAVLM 193

Query: 205 LILTLLDDKIYWHEALLLVLMYTFYI 230
           LI+ L D  + + E+  +V +Y  Y+
Sbjct: 194 LIVALHDGHLTFAESGSMVGLYVVYV 219



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FI  + WI +++  V  +++ +G+ L + D+I GLTI A G SL + V++V V  Q    
Sbjct: 819 FICSMMWIAAIADEVVDVLSTLGEILGLSDAIIGLTIFAVGNSLADLVANVTVA-QFAPA 877

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418
           M  +   G    ++LL +G       LF  S+P +  + D
Sbjct: 878 MAYAACFGGPMLNLLLGVGGSGTYHLLF--SSPHSPIIVD 915



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 24/111 (21%), Positives = 47/111 (42%), Gaps = 4/111 (3%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           ++ L F+     I +  +    + TV    L + +S  G+T LA G   P+  S+     
Sbjct: 83  LFILAFLFSFIGISAADFFCPNLSTVAA-YLGLNESTAGVTFLAFGNGSPDVFSTFSAMS 141

Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFIRI 424
            G   + +   IG+ +F + + +G    ++       P+N +  D+ F  I
Sbjct: 142 SGTLGLAVGELIGAASFIVSIVVGSIAFIRPF---HVPKNAFRRDVIFFTI 189


>UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 704

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 2/135 (1%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155
           + CF+ +G    +Y  P +  I + L +   +AG T +A  +SSP++F           +
Sbjct: 100 ILCFISVGITASEYLCPNLYTISQFLKLPDTLAGLTLLAFGNSSPDVFGTYHAIGSNSLN 159

Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215
           L +  ++G+++F +  V    A+     +  + +   RDCMMY      ++++L+  ++ 
Sbjct: 160 LAIAELIGASLFIMTVVVGTIAIIEPFNVPKNLF--IRDCMMYIMVFALVVISLIIGELT 217

Query: 216 WHEALLLVLMYTFYI 230
               +LLV  Y  Y+
Sbjct: 218 SIICILLVSCYIIYV 232



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 8/110 (7%)

Query: 313 SIYPLTF--IMCITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           SI PLT   I+C   +G  +  YL   + T+    L +PD++ GLT+LA G S P+   +
Sbjct: 91  SILPLTICLILCFISVGITASEYLCPNLYTI-SQFLKLPDTLAGLTLLAFGNSSPDVFGT 149

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTD 418
                     + I+  IG++ F + + +G   +++     + P+N ++ D
Sbjct: 150 YHAIGSNSLNLAIAELIGASLFIMTVVVGTIAIIEPF---NVPKNLFIRD 196



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 19/68 (27%), Positives = 33/68 (48%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FI+ I WI  +S  +  I+ ++     + + I GLTI A G S+ + +S+  +   G   
Sbjct: 555 FILSICWISLISDEIINILHIISIIYQLSEDILGLTIFALGNSIGDFISNYTIAMMGKPI 614

Query: 379 MGISNSIG 386
           M  +   G
Sbjct: 615 MAFTACFG 622


>UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2;
           Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
           - Methanosarcina acetivorans
          Length = 315

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 28/85 (32%), Positives = 51/85 (60%), Gaps = 5/85 (5%)

Query: 326 IGSVSYLVAWIITV-----VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380
           +GS+S ++   I V     + + + +P+ I  LT +A GTSLPE V+++   ++GH  + 
Sbjct: 176 LGSLSVVIGSRILVDSGIKIAEWIGIPEVIIALTAVAIGTSLPELVTAIASLRKGHQDLS 235

Query: 381 ISNSIGSNTFDILLCLGLPWLVKSL 405
           I N +G+NT D+ + LG+   ++ L
Sbjct: 236 IGNILGANTMDVAMILGVSSQIRVL 260



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 31/142 (21%), Positives = 64/142 (45%), Gaps = 3/142 (2%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           LL  FL L    ++ S   D+F+ A   I  +  I   + GAT ++ A+++PE  ++   
Sbjct: 3   LLLIFLFLLSLAMI-SKGSDWFIEAAVAISNKSGIPKMLIGATIVSFATTAPEFAVSATA 61

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208
            ++   D+ +G  VGS + N   V           ++ D + +    M+       LI+ 
Sbjct: 62  AYLGHTDVTIGNAVGSVICNTGLVLGSIIAVKAIPMKDDTFPIKSGLML--LSGIILIIV 119

Query: 209 LLDDKIYWHEALLLVLMYTFYI 230
             D  +   + ++L+L++  ++
Sbjct: 120 SRDGNVNRLDGIILLLVFFAFL 141



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 22/87 (25%), Positives = 38/87 (43%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           F++ +  I   S         + +   +P  + G TI++  T+ PE   S      GH  
Sbjct: 9   FLLSLAMISKGSDWFIEAAVAISNKSGIPKMLIGATIVSFATTAPEFAVSATAAYLGHTD 68

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405
           + I N++GS   +  L LG    VK++
Sbjct: 69  VTIGNAVGSVICNTGLVLGSIIAVKAI 95


>UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1;
           Methanosarcina mazei|Rep: Sodium-calcium exchanger
           protein - Methanosarcina mazei (Methanosarcina frisia)
          Length = 392

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 27/67 (40%), Positives = 42/67 (62%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L VP++I G++++A GTSLPE + +V   + G+ ++ + N IGSN  + LL LG   LV+
Sbjct: 277 LEVPETIIGISLVAVGTSLPELMVTVSAARNGYASIALGNVIGSNITNTLLILGCTGLVQ 336

Query: 404 SLFYPST 410
            L    T
Sbjct: 337 PLMVTGT 343



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 2/124 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV +   I +R  ++  I G T ++  +S PE   +   +F     + +G V+GS + 
Sbjct: 21  DLFVTSSSWIAKRFGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGNVLGSNIA 80

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  + +  AL +   ++ +   + RD  +        +L ++D +I   EA + +L+Y 
Sbjct: 81  NIGLIVSTAALLSN--VKTEELMLRRDGYIMLFSVFLFLLFVVDFRISRFEAFIFLLLYF 138

Query: 228 FYIL 231
            YIL
Sbjct: 139 VYIL 142



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 3/124 (2%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           YF+         L +   I G + +A  +S PEL +           + +G V+GS + N
Sbjct: 265 YFIDKSIFFALLLEVPETIIGISLVAVGTSLPELMVTVSAARNGYASIALGNVIGSNITN 324

Query: 169 VLAVPACCALFAGAVIE-LDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
            L +  C  L    ++     + +T   +++       I T    +I  HE L+L L+Y+
Sbjct: 325 TLLILGCTGLVQPLMVTGTAVYYITPFMLVFSLLLLLFIRT--GWRIKRHEGLILFLLYS 382

Query: 228 FYIL 231
            +++
Sbjct: 383 GFMV 386



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 20/66 (30%), Positives = 36/66 (54%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +     V + I GLT+++ GTS+PE  SS+  + +    + I N +GSN  +I L +   
Sbjct: 30  IAKRFGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGNVLGSNIANIGLIVSTA 89

Query: 400 WLVKSL 405
            L+ ++
Sbjct: 90  ALLSNV 95


>UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+
           antiporter, CaCA family precursor - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 327

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 25/64 (39%), Positives = 39/64 (60%)

Query: 335 WIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394
           W  T + +   V +++ GLT++A GTSLPE  + +   ++  G + I N IGSN F++L 
Sbjct: 197 WAATGLAERAGVAETVVGLTLVAVGTSLPELATCLAAARRSQGDIAIGNIIGSNIFNLLG 256

Query: 395 CLGL 398
            LGL
Sbjct: 257 VLGL 260



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 8/118 (6%)

Query: 68  AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127
           A +   P D  TR  R     LL   L L   L+         V A   + ER  +A  +
Sbjct: 161 APVNGLPEDAPTRLPRA----LLWLLLGLVVLLISAQTA----VWAATGLAERAGVAETV 212

Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
            G T +A  +S PEL         ++GD+ +G ++GS +FN+L V    A      +E
Sbjct: 213 VGLTLVAVGTSLPELATCLAAARRSQGDIAIGNIIGSNIFNLLGVLGLAATLRPVALE 270



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 25/62 (40%), Positives = 34/62 (54%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +   + GLTI+A GTS PE + S L    G   + + N+IGSN  ++ L LGL  L  
Sbjct: 33  LGLSPLLVGLTIVAFGTSAPELLVSALAALAGSPGLAVGNAIGSNIANMGLILGLTALFA 92

Query: 404 SL 405
            L
Sbjct: 93  PL 94



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           +LL   L    F LL +   D FV         L ++  + G T +A  +S+PEL ++ +
Sbjct: 1   MLLQIILLGLSFALL-AWSADRFVLGASATAALLGLSPLLVGLTIVAFGTSAPELLVSAL 59

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
                   L VG  +GS + N+  +    ALFA  +I
Sbjct: 60  AALAGSPGLAVGNAIGSNIANMGLILGLTALFAPLLI 96


>UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+
           antiporter, CaCA family - Alkaliphilus metalliredigens
           QYMF
          Length = 334

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 26/82 (31%), Positives = 48/82 (58%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           + FI+   +I   + L+     ++ + L VP+ +  LT++A GTSLPE  +++    +GH
Sbjct: 176 IMFIVGAVFIALGARLLVNNGVIIANILGVPEQVVSLTLIALGTSLPELTTAISSVVKGH 235

Query: 377 GTMGISNSIGSNTFDILLCLGL 398
             + + N +G+N  DI++ LGL
Sbjct: 236 QGISVGNILGANILDIVMVLGL 257



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 34/150 (22%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+FV +   + +   + + + GAT ++ A++ PEL ++ + T     D+ +G V+GS + 
Sbjct: 22  DWFVESAVWVAKVTGVPNVLIGATIVSIATTLPELLVSVIATQQHYYDVAIGNVIGSMIC 81

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           NV  +     LF+   +    +++    M+       ++  L D  I   E    ++++T
Sbjct: 82  NVGLILGLTTLFSPIKLNRSGFAIRGFFML--GSTALMLFFLRDRMISPREGTWFIVLFT 139

Query: 228 FYILEKINPLDASQRMTPRSV-QNGDLERG 256
            YIL  +   + +Q+  P  + Q  D+ +G
Sbjct: 140 IYILINLQEFNKNQKRVPHVLNQEQDVPQG 169



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 4/67 (5%)

Query: 335 WIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILL 394
           W+  V G    VP+ + G TI++  T+LPE + SV+ T+Q +  + I N IGS   ++ L
Sbjct: 30  WVAKVTG----VPNVLIGATIVSIATTLPELLVSVIATQQHYYDVAIGNVIGSMICNVGL 85

Query: 395 CLGLPWL 401
            LGL  L
Sbjct: 86  ILGLTTL 92


>UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3;
           Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor
           (Sorghum) (Sorghum vulgare)
          Length = 573

 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 20/229 (8%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE-GDLG 157
           F LLG    +YF  ++E +   L +   +AG T ++  + +P++F + V     + G +G
Sbjct: 120 FYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVSFASGDGGGVG 179

Query: 158 VGAVVGSAVFNVLAVPACCALFAGAV---IELDWWSVTRDCMMYXXXXXXLILTLLDDKI 214
           + + +G A+F    V    AL  G     + ++W    RD          L+  L++  I
Sbjct: 180 LSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDLCFLLLALCYLLAVLVNGVI 239

Query: 215 YWHEALLLVLMYTFYIL---------EKINPLDASQRMTPRSVQNGDLERGIEMTRRHDS 265
               A+  V +Y  Y++         EK  P+D S         +GD E  +     H  
Sbjct: 240 TVWVAVSFVSLYVGYVVLVWTSHCCAEKGKPVDESLSAPLLLDDDGD-EDDVPSLPSHSK 298

Query: 266 TGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPD-CRHRHS 313
           T      SS  +  G  +  W  L   L  P+ L    TIPD   HR S
Sbjct: 299 T---TEASSTATSRGRAMLHW--LAGALCMPLYLPRRLTIPDIAGHRWS 342



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ---G 375
           F+M + W  +++  +  ++  +G  + +  S+ G+T+LA G SL + VS+V +      G
Sbjct: 416 FVMSVLWAYTLARELVALLVSIGYVVGIKPSVLGVTVLAWGDSLGDLVSNVAMAVHGGAG 475

Query: 376 HGTMGISNSIGSNTFDILLCLGL 398
                +S       F+ ++ LGL
Sbjct: 476 GAQTAVSGCYAGPLFNTVVGLGL 498



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 1/48 (2%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH-GTMGISNSIGSNTF 390
           L +P ++ G+T+L+ G   P+  +SV+    G  G +G+S+++G   F
Sbjct: 142 LRLPPAVAGVTLLSLGNGAPDVFASVVSFASGDGGGVGLSSALGGALF 189


>UniRef50_Q4RED7 Cluster: Chromosome 10 SCAF15123, whole genome
           shotgun sequence; n=10; Clupeocephala|Rep: Chromosome 10
           SCAF15123, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1007

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 28/96 (29%), Positives = 52/96 (54%), Gaps = 1/96 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           FI+ I  IG ++ ++  + +  G T+ + DS+T +  +A GTS+P+   S V   +  + 
Sbjct: 796 FIVSIIIIGLLTAVIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDMFASKVSAVQDAYA 855

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413
              I N  GSN  ++ L +G+ W V ++++    EN
Sbjct: 856 DASIGNVTGSNAVNVFLGIGMAWSVAAIYWNMKGEN 891



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ++  T MA  SS+PE+ ++ +   G     G+LG   +VGSA FN+  +   C
Sbjct: 97  VSNLTLMALGSSAPEILLSVIEVCGHDFKPGELGPATIVGSAAFNMFVIIGLC 149



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
           ++++ LT++A G+S PE + SV +   GH    G +G +  +GS  F++ + +GL
Sbjct: 95  ETVSNLTLMALGSSAPEILLSV-IEVCGHDFKPGELGPATIVGSAAFNMFVIIGL 148


>UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep:
           Ca2+/Na+ antiporter - Idiomarina loihiensis
          Length = 325

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 1/88 (1%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S  + W    +  +L V D + GLT++A GTSLPE  S++  T++    + + N IGSN 
Sbjct: 188 SRALVWGAVNIAVSLGVSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNM 247

Query: 390 FDILLCLGLPWLVKSL-FYPSTPENHWV 416
           F+ L  +G+   ++ +   P      WV
Sbjct: 248 FNTLAVVGIAGAIEPVSLEPLVLSRDWV 275



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 21/55 (38%), Positives = 32/55 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           L +   + G+ I+  GTS PE V S L + QG+  + + N+ GSN  +I L LG+
Sbjct: 33  LGMAPLVIGMVIIGFGTSAPEMVVSALASMQGNPALALGNAYGSNITNIALVLGI 87



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 13/125 (10%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I   L ++  + G T +A  +S PEL      T   E DL +G V+GS +FN LAV    
Sbjct: 198 IAVSLGVSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNMFNTLAVVG-- 255

Query: 177 ALFAGAV--IELDWWSVTRDCMMYXXXXXXLILTLLD-------DKIYWHEALLLVLMYT 227
              AGA+  + L+   ++RD +        L++  +        ++++    + L L+YT
Sbjct: 256 --IAGAIEPVSLEPLVLSRDWVAMAVLTLLLMVFGIRKARQGRINRVHGFIFICLYLLYT 313

Query: 228 FYILE 232
            Y+L+
Sbjct: 314 LYLLK 318


>UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45;
           Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio
           fischeri (strain ATCC 700601 / ES114)
          Length = 323

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 27/64 (42%), Positives = 38/64 (59%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           V+     + + + GLTI+A GTSLPE  +SV    +G   M   N IGSN F+IL  +G+
Sbjct: 201 VIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAGNIIGSNVFNILAVMGI 260

Query: 399 PWLV 402
           P L+
Sbjct: 261 PALI 264



 Score = 46.4 bits (105), Expect = 0.001
 Identities = 27/88 (30%), Positives = 43/88 (48%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           L+L  V  +  +    +I +   ++  + G T +A  +S PEL  +  G    E D+  G
Sbjct: 185 LILLPVGANMLIDNAVVIAKYFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAG 244

Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELD 187
            ++GS VFN+LAV    AL   + I  D
Sbjct: 245 NIIGSNVFNILAVMGIPALINPSEISPD 272



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 23/56 (41%), Positives = 31/56 (55%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           + G+TILA G+S PE + S      G     + N IGSN  +I L LG+  L+K L
Sbjct: 42  VIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNIANIALILGITALIKPL 97



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 24/115 (20%), Positives = 51/115 (44%), Gaps = 2/115 (1%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           +     I+  + G T +A  SS+PE+ ++       + D  VG V+GS + N+  +    
Sbjct: 32  LARNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNIANIALILGIT 91

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           AL     I      + R+  +           + ++ + ++E LLL+ ++  +I+
Sbjct: 92  ALIKPLAISSA--IIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFII 144


>UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep:
           Slr0681 protein - Synechocystis sp. (strain PCC 6803)
          Length = 433

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 24/58 (41%), Positives = 39/58 (67%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           +  +L + + + GLT++AAGTSLPE  +SV+ + +G   + + N +GSN F+IL  LG
Sbjct: 269 IAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVGNVVGSNIFNILAVLG 326



 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           FI +   +     L+LGS      V +   I + L I+  + G T +AA +S PEL  + 
Sbjct: 242 FIQIAYVVGGVALLVLGS---SLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSV 298

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           V ++  E D+ VG VVGS +FN+LAV    A+F+
Sbjct: 299 VASYRGERDIAVGNVVGSNIFNILAVLGFAAIFS 332



 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 25/56 (44%), Positives = 35/56 (62%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           I GLTI+A GTS+PE V S+     G   + I N +GSN F++LL LG+  ++  L
Sbjct: 106 IIGLTIVAYGTSMPEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPL 161



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 18/58 (31%), Positives = 32/58 (55%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
           I G T +A  +S PE+ ++       + D+ +G VVGS +FNVL +   C++    ++
Sbjct: 106 IIGLTIVAYGTSMPEMVVSLQAAIAGQADISIGNVVGSNIFNVLLILGVCSIITPLIV 163


>UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1;
           Planctomyces maris DSM 8797|Rep: Sodium/calcium
           exchanger protein - Planctomyces maris DSM 8797
          Length = 368

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 2/84 (2%)

Query: 322 CITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGI 381
           C+  +GS   L+     VV     V + + GLTILA GTSLPE   SVL   +GHG +G 
Sbjct: 230 CLVVLGS--RLLVTNAVVVARYFEVSELLIGLTILAIGTSLPEYTISVLSIIKGHGALGT 287

Query: 382 SNSIGSNTFDILLCLGLPWLVKSL 405
            N IG+N  +I + + +  L+  L
Sbjct: 288 GNIIGANVLNINMVIAICALIHPL 311



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 29/93 (31%), Positives = 47/93 (50%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +L+C L +   +L  +   D F  +   I     I   I GAT ++ +++ PEL ++  G
Sbjct: 23  ILYCSLLILLGMLSITKGGDLFTDSSVEIARLTRIPPVIIGATIVSMSTTFPELMVSVTG 82

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG 181
           T   +GDL VG  +GS + N+  +   CAL  G
Sbjct: 83  TLAGKGDLAVGNALGSCLCNIGLIIGSCALLKG 115



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F L   F    C ++LGS      V    ++     ++  + G T +A  +S PE  I+ 
Sbjct: 219 FKLALMFFCGACLVVLGS---RLLVTNAVVVARYFEVSELLIGLTILAIGTSLPEYTISV 275

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           +      G LG G ++G+ V N+  V A CAL
Sbjct: 276 LSIIKGHGALGTGNIIGANVLNINMVIAICAL 307



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 21/58 (36%), Positives = 33/58 (56%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           +P  I G TI++  T+ PE + SV  T  G G + + N++GS   +I L +G   L+K
Sbjct: 57  IPPVIIGATIVSMSTTFPELMVSVTGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLK 114


>UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein
           precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+
           antiporter, CaCA family protein precursor - Psychromonas
           ingrahamii (strain 37)
          Length = 320

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 25/66 (37%), Positives = 42/66 (63%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + +  NVP+++ GLT++A GTSLPE   SV+   + H  + + N +GSN F++L  LG+ 
Sbjct: 199 IAEHFNVPEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGILGVS 258

Query: 400 WLVKSL 405
             ++ L
Sbjct: 259 SFLQPL 264



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 24/55 (43%), Positives = 32/55 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           L V   ++GL I+  GTS PE V SV    +G   + I N +GSN  +ILL LG+
Sbjct: 32  LGVSPLLSGLVIVGFGTSAPELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGI 86



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 19/56 (33%), Positives = 31/56 (55%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I E  N+   + G T +A  +S PEL I+ +       D+ VG ++GS +FN+L +
Sbjct: 199 IAEHFNVPEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGI 254



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 17/67 (25%), Positives = 36/67 (53%)

Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           +RL ++  ++G   +   +S+PEL ++       + D+ +G VVGS + N+L +   CA+
Sbjct: 30  KRLGVSPLLSGLVIVGFGTSAPELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAV 89

Query: 179 FAGAVIE 185
                ++
Sbjct: 90  ITPLAVK 96


>UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1;
           Arabidopsis thaliana|Rep: Na/Ca,K-exchanger-like protein
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 559

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 7/150 (4%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFIN 145
           G  LL  +L L  F LLG    +YF  ++E + + LN++  +AG T ++  + +P+LF +
Sbjct: 91  GQFLLFLWLLLL-FYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFAS 149

Query: 146 CVGTFVTEG----DLGVGAVVGSAVFNVLAVPACCAL-FAGAVIELDWWSVTRDCMMYXX 200
            V +F+ E     D+G+  VVG + F    V    ++      + ++  +  RD   +  
Sbjct: 150 LV-SFMGESKGTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCA 208

Query: 201 XXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
               L L L+  KI +  AL    +Y  Y+
Sbjct: 209 AIGSLALILVYGKINFWGALGFCSLYAVYV 238



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 5/84 (5%)

Query: 319 FIMCITWIG-SVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSV-LVTKQGH 376
           F+M +TW   S   LVA ++T +G    V  SI GLT+LA G S+ + ++++ +    G+
Sbjct: 402 FVMSMTWSYISAQELVA-LLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALHDGN 460

Query: 377 --GTMGISNSIGSNTFDILLCLGL 398
               + +S       F+ L  LG+
Sbjct: 461 EGAQVAVSGCYAGPIFNTLFALGI 484


>UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_11,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 498

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 33/146 (22%), Positives = 69/146 (47%), Gaps = 1/146 (0%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           FIL+  F+ L  F  + ++   Y  PAIE I E+LNI+  ++  T +A A+ + ++    
Sbjct: 49  FILMAIFVVLIVFRFMSTLVMFYLTPAIEFITEKLNISQSLSAVTLLAFANGAGDVVTAI 108

Query: 147 VGTFVTEG-DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXL 205
           V T   +     +G++ G+  F    V     + + + I +  + + RD + Y      +
Sbjct: 109 VATETLDAISYNIGSLYGAGFFVATLVVGITIINSQSYIVMKSYFIWRDILFYIVATIIV 168

Query: 206 ILTLLDDKIYWHEALLLVLMYTFYIL 231
           I+  +  +    ++  L+L+Y   ++
Sbjct: 169 IIYGIVGEFSLIDSAFLLLIYIILVI 194



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 26/86 (30%), Positives = 50/86 (58%)

Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           I+ + WI  +S ++   +T  G   N+ ++  G+TI+A G +LP+ + ++ + KQG+  M
Sbjct: 338 IVSLVWIYCLSGILIDTLTFFGMLTNLSNTYLGMTIIAMGNALPDGIVTMTLAKQGYAVM 397

Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL 405
           GI+ +     F +L+ LG+  L  +L
Sbjct: 398 GITGAYFGQIFGLLVGLGISLLKTNL 423


>UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome D of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 638

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 14/174 (8%)

Query: 98  CFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE--GD 155
           CF+LLG    D+  P +  + +  N +  +  +  +A  +SSP+LF N +    +E    
Sbjct: 39  CFVLLGICASDHLCPNVAYLTKSGNTSKGVIASILLAWCNSSPDLFSNLISWLNSESPAT 98

Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILT-----LL 210
           L +G V+GS    +  +     LF     +LD   V R+ ++       L +T     ++
Sbjct: 99  LSLGEVLGSCGIIICIIQG--LLFYCMKEQLDLTIVQRNSLVTDLLFALLAMTCVLWIVV 156

Query: 211 DDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQN-----GDLERGIEM 259
            + + W+ + ++V +Y  Y++ K+   D+ Q     +  N     G LE G  M
Sbjct: 157 ANSVTWYASFIMVAIYVMYVVSKMKLHDSLQGTDDSNKDNIIVGSGRLENGFTM 210


>UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Eubacterium ventriosum ATCC 27560
          Length = 339

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 26/58 (44%), Positives = 38/58 (65%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +++ GLTI+A GTSLPE V+S +   +G   + I N +GSN  +ILL LGL   + S+
Sbjct: 226 ETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGLSAAISSV 283



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 25/66 (37%), Positives = 37/66 (56%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           V   L VP  + GLTI+A GTSLPE   S     +    + + N +GSN F++L+ +G+ 
Sbjct: 31  VAKRLRVPSIVIGLTIVAVGTSLPELAVSTFAAVKHSNAIALGNVVGSNIFNLLMVIGIT 90

Query: 400 WLVKSL 405
            L K +
Sbjct: 91  ALFKDM 96



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +L   L L  F+LL     DYFV     + +RL + S + G T +A  +S PEL ++   
Sbjct: 4   ILDIILLLVGFVLLIKGA-DYFVDGSCAVAKRLRVPSIVIGLTIVAVGTSLPELAVSTFA 62

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
                  + +G VVGS +FN+L V    ALF   +++
Sbjct: 63  AVKHSNAIALGNVVGSNIFNLLMVIGITALFKDMLVK 99



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAG- 181
           ++  + G T +A  +S PEL  + V     E DL +G VVGS + N+L V    A  +  
Sbjct: 224 MSETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGLSAAISSV 283

Query: 182 AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
            V  +++  +    +         I+      I   E + LV++Y FY+
Sbjct: 284 GVTAMNFVDI---IVSLAATIIVFIVASTQRTIKKKEGIFLVIIYAFYM 329


>UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
           Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA
           family - Rhodobacter sphaeroides (strain ATCC 17029 /
           ATH 2.4.9)
          Length = 305

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 25/65 (38%), Positives = 40/65 (61%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +  +  + +++ GLTI+A GTSLPE  +S +   + H  + + N IGSN F++L  LG
Sbjct: 186 TQIARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGILG 245

Query: 398 LPWLV 402
           +  LV
Sbjct: 246 ITGLV 250



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 23/63 (36%), Positives = 35/63 (55%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           V  +  +   + GLTI+  GTS PE + S+     G  ++ + N +GSN  +ILL LGL 
Sbjct: 27  VARSYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIANILLILGLT 86

Query: 400 WLV 402
            L+
Sbjct: 87  ALI 89



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 18/56 (32%), Positives = 30/56 (53%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I     I+  + G T +A  +S PEL  + +  +    ++ VG V+GS +FNVL +
Sbjct: 188 IARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGI 243



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 2/116 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           ++ V     +     I+  + G T +   +S+PEL ++          + VG V+GS + 
Sbjct: 18  EFLVRGAANVARSYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIA 77

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223
           N+L +    AL     + +D   V +D          L + LL D +   EA +LV
Sbjct: 78  NILLILGLTALI--YPVAVDGRRVWKDLAFMVGATVLLWIMLLGDGLSRIEAGVLV 131


>UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2;
           Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya
           sp. PCC 8106
          Length = 315

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 33/91 (36%), Positives = 49/91 (53%)

Query: 314 IYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           I+ L F++ +  +   S +       +G +L     I G+TI+A GTSLPE VSS+    
Sbjct: 6   IWILVFVVSLIVLIKFSDIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVY 65

Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           QG   +  SN IGSN  +I L +G+  L+ S
Sbjct: 66  QGATEIVASNVIGSNVANIFLIIGVATLLSS 96



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 23/72 (31%), Positives = 40/72 (55%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           I  + D L +   +  ++ +A GTSLPE   +   +++G   + I N +GSN F+ L+ +
Sbjct: 194 IIKIADILGIGKELIAISAVALGTSLPELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVM 253

Query: 397 GLPWLVKSLFYP 408
           G+P L + L  P
Sbjct: 254 GVPGLFEDLIIP 265



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 13/169 (7%)

Query: 65  CTPAAILEFPSDGLTR--FQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
           C      E PSDG TR  +  +   +LL C   ++    LG+   ++ + +I  I + L 
Sbjct: 150 CGQVETPEMPSDGSTRSSYLFKQIIVLLICTACMF----LGA---NFTIQSIIKIADILG 202

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           I  ++   + +A  +S PEL +    +   + ++ +G V+GS +FN L V     LF   
Sbjct: 203 IGKELIAISAVALGTSLPELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVMGVPGLFEDL 262

Query: 183 VIELDWWSVTRDCM-MYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           +I  D   + RD + M             D K+   E  L  ++Y ++I
Sbjct: 263 IIP-D--IIIRDGLPMLLASTLLFFFVTQDKKVTKWEGWLFFVLYAWFI 308



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 4/144 (2%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D F      I   L  +  I G T +A  +S PEL  +    +    ++    V+GS V 
Sbjct: 23  DIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVYQGATEIVASNVIGSNVA 82

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  +     L + + +++ +  +  D  ++      L  TL D    + EA+L +L Y 
Sbjct: 83  NIFLIIGVATLLS-SPLKITYNLLDVDLPLFVGSAFLLYFTLSDGDFSFGEAILCILAYL 141

Query: 228 FYILEKINPLDASQRMTPRSVQNG 251
            ++   I      Q  TP    +G
Sbjct: 142 IHLTYTIR---CGQVETPEMPSDG 162


>UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH0465
           protein - Bacillus halodurans
          Length = 318

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 28/62 (45%), Positives = 39/62 (62%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           LNV   + GLTI+A GTS PEA +S++    G+  + + N IGSN F+I L +GL  L+ 
Sbjct: 31  LNVSPLLIGLTIVAFGTSSPEATASIIAALNGNPDVALGNVIGSNMFNITLVVGLTALLS 90

Query: 404 SL 405
            L
Sbjct: 91  PL 92



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 97  YCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           Y  LLLG        D+FV     I   LN++  + G T +A  +SSPE   + +     
Sbjct: 3   YVLLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNG 62

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
             D+ +G V+GS +FN+  V    AL +  ++
Sbjct: 63  NPDVALGNVIGSNMFNITLVVGLTALLSPLIV 94



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 21/60 (35%), Positives = 36/60 (60%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +  +  + +++ GLTI+A GTSLPE V+S+    +    + + N +GS+ F+I   LG
Sbjct: 198 TAIAFSHGMSETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFNIFFVLG 257



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 2/109 (1%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           ++  + G T +A  +S PEL  +       E ++ +G +VGS++FN+  V    A     
Sbjct: 206 MSETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFNIFFVLGTAATI--T 263

Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            + +D   V    ++       L+ +     +  +E L+L   Y  Y++
Sbjct: 264 PMHVDSRVVVDLLLLIFLTLLLLVFSRTRYTVGKYEGLILASFYIGYMV 312


>UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6;
           Bacteria|Rep: Sodium/calcium exchanger - Shewanella
           oneidensis
          Length = 316

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 28/57 (49%), Positives = 38/57 (66%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           V + I GLTI+A GTS+PE V+SVL   +G   + I N +GSN F+IL  LG+  +V
Sbjct: 198 VSEIIIGLTIVAIGTSMPELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAIV 254



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 25/68 (36%), Positives = 37/68 (54%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +   L +   + GLTI+A GTS PE   SV     G+  + + N IGSN  +I L LG
Sbjct: 26  TTIALRLGITPLVIGLTIVAFGTSAPELAVSVKAALAGNSGIALGNVIGSNIVNIGLILG 85

Query: 398 LPWLVKSL 405
           +  L++ +
Sbjct: 86  ITALIRPI 93



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 93  FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           F+A+   +L+G      FV     + +   ++  I G T +A  +S PEL  + +     
Sbjct: 170 FIAVGISMLVGGGI--LFVNGAVDLAKVFGVSEIIIGLTIVAIGTSMPELVTSVLAALKG 227

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCAL 178
           + D+ +G +VGS +FN+L +    A+
Sbjct: 228 QSDIAIGNIVGSNIFNILGILGVTAI 253



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 3/133 (2%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
           FL+L ++  +  V     I  RL I   + G T +A  +S+PEL ++          + +
Sbjct: 11  FLIL-TLGAEALVRGATTIALRLGITPLVIGLTIVAFGTSAPELAVSVKAALAGNSGIAL 69

Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218
           G V+GS + N+  +    AL     IE+    V RD  +           LLD ++   +
Sbjct: 70  GNVIGSNIVNIGLILGITALI--RPIEVKSEMVKRDIPIMILASMLFWGLLLDGELSLID 127

Query: 219 ALLLVLMYTFYIL 231
            ++L+     Y++
Sbjct: 128 GVILLSFMLGYLV 140


>UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;
           Loktanella vestfoldensis SKA53|Rep: Putative
           sodium/calcium exchanger - Loktanella vestfoldensis
           SKA53
          Length = 305

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 1/86 (1%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           LT +  +T +    YLV    +++     V +++ GL+I+A GTSLPE  ++V+   +G 
Sbjct: 165 LTILGLVTVMVGAHYLVQ-SASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGE 223

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLV 402
             + + N +GSN F+IL  LG+  +V
Sbjct: 224 RDIALGNIVGSNIFNILAILGITAVV 249



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 20/64 (31%), Positives = 35/64 (54%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           Y V +  II  +  ++  + G + +A  +S PEL    +     E D+ +G +VGS +FN
Sbjct: 179 YLVQSASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMAAIRGERDIALGNIVGSNIFN 238

Query: 169 VLAV 172
           +LA+
Sbjct: 239 ILAI 242



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 2/123 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V     +  R  +A  I GA  +   +S+PEL ++       +  + +G V+GS + 
Sbjct: 19  DWLVKGASGLALRFGVAPIIVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIA 78

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+L V    AL    V  L +  V +D +        L       ++   E L+L+    
Sbjct: 79  NILLVLGTAALIGPLV--LTFADVRKDLLWMTGAVLFLPYAFWSGEVSHVEGLVLIGALA 136

Query: 228 FYI 230
            Y+
Sbjct: 137 VYL 139



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 22/56 (39%), Positives = 29/56 (51%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           I G  ++  GTS PE + S+     G   + I N IGSN  +ILL LG   L+  L
Sbjct: 38  IVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIANILLVLGTAALIGPL 93


>UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter,
           CaCA family - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 311

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 22/63 (34%), Positives = 41/63 (65%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + +   +P  + G++++A GTSLPE  +S++   +  G++ I N +GSN F++LL LG+ 
Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGIS 251

Query: 400 WLV 402
            L+
Sbjct: 252 LLL 254



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 21/53 (39%), Positives = 30/53 (56%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +  ++ G TI+A GTSLPE V S      G+  + + N IGSN  ++ L L L
Sbjct: 35  ISPALIGSTIIAFGTSLPELVVSTNAAVTGNSGIALGNVIGSNIANVALVLAL 87



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 20/68 (29%), Positives = 34/68 (50%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + E   I + + G + +A  +S PEL  + V     EG + +G ++GS +FN+L V    
Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGIS 251

Query: 177 ALFAGAVI 184
            L A   +
Sbjct: 252 LLLAPVTV 259



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 21/77 (27%), Positives = 35/77 (45%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV     +  R  I+  + G+T +A  +S PEL ++          + +G V+GS + 
Sbjct: 20  DLFVGGGSGLALRYRISPALIGSTIIAFGTSLPELVVSTNAAVTGNSGIALGNVIGSNIA 79

Query: 168 NVLAVPACCALFAGAVI 184
           NV  V A C      ++
Sbjct: 80  NVALVLALCTFIRPGMV 96


>UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep:
           Sodium/calcium exchanger 3 precursor
           (Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human)
          Length = 927

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           +L+A +P   + H      F + I  IG ++ ++  + +  G T+ + DS+T +  +A G
Sbjct: 741 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 798

Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           TS+P+  +S     Q  +    I N  GSN  ++ L +GL W V ++++
Sbjct: 799 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 847



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ++  T MA  SS+PE+ ++ +   G     GDLG   +VGSA FN+  +   C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
           ++++ LT++A G+S PE + S L+   GH    G +G S  +GS  F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184


>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
            n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
            exchanger protein - Tetrahymena thermophila SB210
          Length = 5392

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 4/187 (2%)

Query: 82   QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141
            Q     I+L   ++L  F LL S  E Y  PA+  I + L  +  +AG T +A  + +P+
Sbjct: 4832 QNVPSLIILTIVISLVAFHLLSSTAESYLSPALAKISDSLKCSQTLAGVTLLALGNGAPD 4891

Query: 142  LFINCV--GTFVTEG-DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMY 198
            +F   +  G    EG +L +G++ G+ +F V  V     +     ++ D     RD   Y
Sbjct: 4892 VFTAIIAGGGNDDEGINLAIGSIFGAGLF-VTTVTLAKVIKNSDELKADKNIFIRDVGFY 4950

Query: 199  XXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQNGDLERGIE 258
                  +++ LL  K+ +  A+    +Y  +I+  I     ++R     +    +    E
Sbjct: 4951 CFAAFLILIYLLIGKVNFPMAVAFFSLYFVFIIVVIYQEWDAKRKRKNGINAQLISDENE 5010

Query: 259  MTRRHDS 265
            +  RH S
Sbjct: 5011 LQNRHMS 5017



 Score = 36.3 bits (80), Expect = 1.5
 Identities = 18/60 (30%), Positives = 31/60 (51%)

Query: 345  NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
            NV  +  GLT LA G S  +  ++  + K G+G M ++       F+ LL  G+  ++K+
Sbjct: 5284 NVNKAYLGLTFLAFGNSAGDFFTNPQLAKMGYGIMAMTGCFAGQLFNTLLGFGIALILKT 5343


>UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1;
           Pirellula sp.|Rep: Putative uncharacterized protein -
           Rhodopirellula baltica
          Length = 339

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 26/55 (47%), Positives = 38/55 (69%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           L V + + GLTI++AGTSLPE V+SV  T +G   + I N++GS T +I+  LG+
Sbjct: 218 LGVSELVIGLTIVSAGTSLPELVTSVAATIKGERGIAIGNAVGSTTLNIVAVLGI 272



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 1/124 (0%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV     +   L ++  + G T ++A +S PEL  +   T   E  + +G  VGS   
Sbjct: 205 DLFVDGAVSMARILGVSELVIGLTIVSAGTSLPELVTSVAATIKGERGIAIGNAVGSTTL 264

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDC-MMYXXXXXXLILTLLDDKIYWHEALLLVLMY 226
           N++AV    ++ A + + +    +  D  +M        IL      I   E +L++++Y
Sbjct: 265 NIVAVLGITSVIAPSGLNVADEILRLDMPLMVIAAMLSWILYRTGRTIVRWEGVLMIVIY 324

Query: 227 TFYI 230
             Y+
Sbjct: 325 CSYV 328



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 316 PLTFIMCITWIGSVSYLVA---WII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSV 369
           P+  I+ +  +G V  L+    W++   + +     +     GLT+++ GTS PE   S 
Sbjct: 6   PMNGIIALQILGGVLLLLIGGEWVVRGASRLAIAAKLSPLFVGLTVVSLGTSAPEMAVSF 65

Query: 370 LVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
               +G   + I N +GSN F++L+ +G   L   L
Sbjct: 66  ATALRGQADITIGNVVGSNLFNMLMIVGFSALFAPL 101



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 30/115 (26%), Positives = 59/115 (51%), Gaps = 8/115 (6%)

Query: 120 RLNIASDIA----GATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           RL IA+ ++    G T ++  +S+PE+ ++       + D+ +G VVGS +FN+L +   
Sbjct: 35  RLAIAAKLSPLFVGLTVVSLGTSAPEMAVSFATALRGQADITIGNVVGSNLFNMLMIVGF 94

Query: 176 CALFAGAVIELDWWSVTR-DCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            ALFA   ++     +TR D  +       +++  L+  I   + ++L+L+   Y
Sbjct: 95  SALFAPLPVDR---QITRFDVPVMIAATIAMLVASLNGIIGRFDGIVLILIMIGY 146


>UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
           Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
           - Parvibaculum lavamentivorans DS-1
          Length = 334

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 27/64 (42%), Positives = 40/64 (62%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           V DS+ GLT++A GTSLPE  +SVL   +    + I N +GSN F++L   G+  +VK +
Sbjct: 223 VSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPV 282

Query: 406 FYPS 409
             P+
Sbjct: 283 PVPA 286



 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%)

Query: 309 RHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           R +   Y    +  +  +G   +LV    ++    L V   + GLT++  GTS PE V+S
Sbjct: 14  REQELTYLFLVVGLVLLLGGAEFLVKGAASLA-TRLGVSPFLIGLTLVGFGTSAPELVAS 72

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           +    QG+  + + N +GSN  +ILL LG+  L+
Sbjct: 73  LEGAFQGYPGIAVGNVVGSNIANILLILGIAGLI 106



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 2/118 (1%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           A+EI   R  ++  + G T +A  +S PE+  + +  F  + D+ +G VVGS +FNVL +
Sbjct: 214 AVEI-ATRHGVSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGI 272

Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
               A+     +  D        +M       L+      +I   EALLL+  Y  Y+
Sbjct: 273 AGMVAVVKPVPVPADIAGFD-IWVMGAASLLFLVFAWTGSRIGRVEALLLLGGYGAYV 329



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 80  RFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSS 139
           RF+ Q    L + FL +   LLLG    ++ V     +  RL ++  + G T +   +S+
Sbjct: 12  RFREQE---LTYLFLVVGLVLLLGGA--EFLVKGAASLATRLGVSPFLIGLTLVGFGTSA 66

Query: 140 PELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           PEL  +  G F     + VG VVGS + N+L +
Sbjct: 67  PELVASLEGAFQGYPGIAVGNVVGSNIANILLI 99


>UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1;
           Moritella sp. PE36|Rep: Putative uncharacterized protein
           - Moritella sp. PE36
          Length = 340

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 3/142 (2%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           +LL     L  F+LL +V  D  +     + ++  ++    G T +A  +S PEL ++ +
Sbjct: 3   LLLPIIAVLVGFILL-TVSADRLILVSSTLAKQFGVSVMFIGMTVIAFGTSFPELVVSAI 61

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207
            +F     L VG  +GS + N   V A CALF   VI++ +  + R+  +        I 
Sbjct: 62  ASFNGAEGLAVGNAIGSNIINCGLVLALCALFMPLVIKVRF--IKRELPILVFALIATIA 119

Query: 208 TLLDDKIYWHEALLLVLMYTFY 229
            + +  I   ++L+L+L+   Y
Sbjct: 120 LMSNGSITMWDSLILILLLALY 141



 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 26/73 (35%), Positives = 42/73 (57%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S ++ W    +   + V D + GLTI+A GTSLPE  +++   ++G   +  +  IGSNT
Sbjct: 183 SQIMVWGSVQLAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNT 242

Query: 390 FDILLCLGLPWLV 402
           F++L  L  P L+
Sbjct: 243 FNLLGVLAFPGLI 255



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 19/47 (40%), Positives = 28/47 (59%)

Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           G+T++A GTS PE V S + +  G   + + N+IGSN  +  L L L
Sbjct: 43  GMTVIAFGTSFPELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLAL 89



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + + + ++  + G T +A  +S PEL     G      ++    V+GS  FN+L V A  
Sbjct: 193 LAKAMGVSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNTFNLLGVLAFP 252

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILT 208
            L  G  ++L    +TRD  M       ++++
Sbjct: 253 GLI-GDGLQLPAEVLTRDLPMLSIMTAFMVIS 283


>UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2;
           Hyphomonadaceae|Rep: Sodium/calcium exchanger -
           Oceanicaulis alexandrii HTCC2633
          Length = 334

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 29/73 (39%), Positives = 40/73 (54%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +     VP  + GLTI+A GTS PE V S     +G   + I N +GSN  ++LL LG
Sbjct: 30  TALASKAGVPPLLVGLTIVAFGTSAPEMVVSAAAAVEGAPGLAIGNIVGSNIANVLLVLG 89

Query: 398 LPWLVKSLFYPST 410
           LP L+  +   +T
Sbjct: 90  LPALLAPIASTAT 102



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 27/60 (45%), Positives = 37/60 (61%)

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           NVPD++ GLTILA GTSLPE  ++++   +    M I N +GSN F+I    G+  L  S
Sbjct: 208 NVPDAVIGLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAAS 267



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 22/64 (34%), Positives = 31/64 (48%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I    N+   + G T +A  +S PEL    V     + D+ +G VVGS +FN+ AV    
Sbjct: 203 IAALFNVPDAVIGLTILAFGTSLPELATALVAALRKQADMAIGNVVGSNIFNISAVGGIT 262

Query: 177 ALFA 180
            L A
Sbjct: 263 GLAA 266



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 94  LALYCFLLLGSVCE-----DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           + L+  ++LG +       D  V     +  +  +   + G T +A  +S+PE+ ++   
Sbjct: 4   ILLFSLMVLGGIVVLLTGGDILVRGATALASKAGVPPLLVGLTIVAFGTSAPEMVVSAAA 63

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
                  L +G +VGS + NVL V    AL A
Sbjct: 64  AVEGAPGLAIGNIVGSNIANVLLVLGLPALLA 95


>UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25;
           Enterobacteriaceae|Rep: Inner membrane protein yrbG -
           Escherichia coli (strain K12)
          Length = 325

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 24/65 (36%), Positives = 41/65 (63%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           TV+ +   + +   GLT +A GTSLPE  +++   ++G   + + N IG+N F+I++ LG
Sbjct: 198 TVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLG 257

Query: 398 LPWLV 402
           LP L+
Sbjct: 258 LPALI 262



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 23/61 (37%), Positives = 37/61 (60%)

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           T  +P  I G+T+++ GTSLPE + S+  +      + +  ++GSN  +ILL LGL  LV
Sbjct: 32  TFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALV 91

Query: 403 K 403
           +
Sbjct: 92  R 92



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 26/88 (29%), Positives = 40/88 (45%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           LLL     D  V A  I+C    I   I G T ++  +S PE+ ++   +   + DL VG
Sbjct: 12  LLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVG 71

Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELD 187
             +GS + N+L +    AL     +  D
Sbjct: 72  TALGSNIINILLILGLAALVRPFTVHSD 99



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 4/140 (2%)

Query: 55  LLGIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAI 114
           LL IV++ R            + L    R  G  +   FL L   L++  V     V   
Sbjct: 140 LLFIVKLARQAERQGTDSLTREQLAELPRDGGLPV--AFLWLGIALIIMPVATRMVVDNA 197

Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174
            ++     I+    G T +A  +S PEL     G    E D+ VG ++G+ +FN++ V  
Sbjct: 198 TVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLG 257

Query: 175 CCALFAGAVIELDWWSVTRD 194
             AL      E+D  + +RD
Sbjct: 258 LPALITPG--EIDPLAYSRD 275


>UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1;
           Takifugu rubripes|Rep: Sodium/calcium exchanger 2
           precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu
           rubripes
          Length = 953

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 30/109 (27%), Positives = 58/109 (53%), Gaps = 3/109 (2%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           IL+A IP   + +      FI+ +  IG ++ ++  + +  G T+ + D++T +  +A G
Sbjct: 767 ILFACIPPTEYWNGW--ACFIVSVVGIGFLTAIIGDVASHFGCTVGLRDTVTAVVFVALG 824

Query: 360 TSLPEA-VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
           TSLP+   S    T+  +    + N  GSN  ++ L +GL W V ++++
Sbjct: 825 TSLPDTFASKFAATQDQYADACVGNVTGSNAVNVFLGIGLAWSVAAVYW 873



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA--- 180
           ++  T MA  SS+PE+ ++ +   G     G+LG G +VGSA FN+  +   C L     
Sbjct: 80  VSNLTLMALGSSAPEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLCVLIIPEG 139

Query: 181 --GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYIL 231
               +  L  + VT    ++      LIL ++   I   W   + LV    F IL
Sbjct: 140 EHRRIKHLRVYFVTAFWSVFAYIWLYLILAVISPGIVEVWEAVVTLVYFPLFVIL 194



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 348 DSITGLTILAAGTSLPEAVSSVL-VTKQGH--GTMGISNSIGSNTFDILLCLGLPWLV 402
           ++++ LT++A G+S PE + SV+ V   G   G +G    +GS  F++ + +GL  L+
Sbjct: 78  ETVSNLTLMALGSSAPEILLSVIEVCGHGFNAGELGPGTIVGSAAFNMFVIIGLCVLI 135


>UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF10698,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 793

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 1/95 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           F++ I+ IG ++ ++  I +  G T+ + DS+T +  +A GTS+P+   S V   +  + 
Sbjct: 624 FMVSISIIGVLTAIIGDIASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVSAVQDQYA 683

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPE 412
              I N  GSN  ++ L +G+ W + ++++ S  E
Sbjct: 684 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGE 718



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 4/69 (5%)

Query: 112 PAIEIICERLNIASD-IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVF 167
           P  E I  R+ + ++ ++  T MA  SS+PE+ ++ V   G     G+LG   +VGSA F
Sbjct: 54  PGGEKISTRVRVWNETVSNLTLMALGSSAPEILLSVVEVCGHNFNAGELGPNTIVGSAAF 113

Query: 168 NVLAVPACC 176
           N+  +   C
Sbjct: 114 NMFVIIGLC 122



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 5/55 (9%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
           ++++ LT++A G+S PE + SV V   GH    G +G +  +GS  F++ + +GL
Sbjct: 68  ETVSNLTLMALGSSAPEILLSV-VEVCGHNFNAGELGPNTIVGSAAFNMFVIIGL 121


>UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 313

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 2/114 (1%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I + L ++  + G T +AA +S PEL  + V  +  + D+ +G +VGS +FN+L +   C
Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC 253

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           +L     IE    +     +M       L L     KI   E  +L+L Y  Y+
Sbjct: 254 SLI--HPIEAKNVNYIDLLVMLGISVLLLPLVKSGQKISRTEGFVLILFYVIYM 305



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 23/58 (39%), Positives = 36/58 (62%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           +   L V +++ GLTI+AAGTS+PE  +S++   +    + I N +GSN F+IL   G
Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAG 251



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 24/49 (48%), Positives = 32/49 (65%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + GLTI+A GTS PE V S+  T  G G + I N +GSN F+I + LG+
Sbjct: 39  VVGLTIVAFGTSAPELVVSLNATLSGQGDIAIGNIVGSNIFNIGVILGV 87



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 18/61 (29%), Positives = 34/61 (55%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           + V     +  +  I+  + G T +A  +S+PEL ++   T   +GD+ +G +VGS +FN
Sbjct: 21  WLVQGSSALALKAKISPLVVGLTIVAFGTSAPELVVSLNATLSGQGDIAIGNIVGSNIFN 80

Query: 169 V 169
           +
Sbjct: 81  I 81


>UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Parvularcula bermudensis
           HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Parvularcula bermudensis HTCC2503
          Length = 327

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 25/66 (37%), Positives = 38/66 (57%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +   L +P  + GLTI+A GTS PE V S+     G   + + N +GSN  ++ L LGLP
Sbjct: 29  IATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGSNIANVFLVLGLP 88

Query: 400 WLVKSL 405
            L+ ++
Sbjct: 89  ALISAI 94



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 21/54 (38%), Positives = 33/54 (61%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           L V + + GLT++A GTSLPE  + +   ++   ++ + N IGSN F+IL   G
Sbjct: 204 LGVREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFNILFVGG 257



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 25/76 (32%), Positives = 37/76 (48%)

Query: 105 VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGS 164
           V  D+ V     I  RL I S + G T +A  +S+PEL ++       +  + VG +VGS
Sbjct: 17  VAGDFLVRGAVGIATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGS 76

Query: 165 AVFNVLAVPACCALFA 180
            + NV  V    AL +
Sbjct: 77  NIANVFLVLGLPALIS 92



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 29/111 (26%), Positives = 43/111 (38%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L +  ++ G T +A  +S PEL          E  + VG V+GS +FN+L V     +F 
Sbjct: 204 LGVREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFNILFVGGAMGVFG 263

Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
             V       +     M        I   L   I     +L +L Y  YI+
Sbjct: 264 TTVFSDPGTKIYDVPAMVVAALALAIPLYLRMTITRTVGILFILAYIAYIV 314


>UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2;
           Caenorhabditis|Rep: Na/ca exchangers protein 10 -
           Caenorhabditis elegans
          Length = 668

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 25/83 (30%), Positives = 46/83 (55%), Gaps = 3/83 (3%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           I++     L+ F+++  V +D+F P+I  I   L I+  IAG TF+A  + +P++F +  
Sbjct: 104 IIISIIYLLFLFVVMTVVADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIA 163

Query: 148 GTFVT---EGDLGVGAVVGSAVF 167
               T   + DL +G ++G  +F
Sbjct: 164 SVITTPKPKADLAIGDIIGGGIF 186



 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 29/77 (37%), Positives = 42/77 (54%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F+M I WI ++S  +  +IT++G    V   I GLTI+A    + + VS V V KQG 
Sbjct: 495 LGFLMSIAWIYTISSEIINVITMIGVATGVSQEILGLTIMAWSNCIGDIVSDVAVVKQGF 554

Query: 377 GTMGISNSIGSNTFDIL 393
             M ++ +IG   F  L
Sbjct: 555 PKMAMAAAIGGPLFSKL 571


>UniRef50_Q5CI48 Cluster: Cation exchanger; n=2;
           Cryptosporidium|Rep: Cation exchanger - Cryptosporidium
           hominis
          Length = 940

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 29/86 (33%), Positives = 48/86 (55%)

Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           IM I W G +   +   I V+G TL +  +I GLTI+A G S+ +  ++V V++ GH  M
Sbjct: 790 IMSIYWNGVLVNELVECIKVIGLTLGIKPAILGLTIVAMGNSIADLFANVAVSRAGHAHM 849

Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL 405
           G++   G+  F +L   G    V+++
Sbjct: 850 GLAGCYGACVFLLLFGFGSSVFVRAI 875



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 23/94 (24%), Positives = 50/94 (53%), Gaps = 5/94 (5%)

Query: 92  CFLALYCFLLL--GSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149
           C L   C L +  G+V + Y    +  + E L+++   AG+T +A ++++ ++ +  +  
Sbjct: 104 CLLVWSCILFIACGTVADTYISSLMIKLAECLSLSDTFAGSTLLAFSNAASDVILGIISV 163

Query: 150 FVTEG---DLGVGAVVGSAVFNVLAVPACCALFA 180
            + E    D+ +G V+G+ +F +L V  C  +F+
Sbjct: 164 SIGEKDAVDVFLGDVIGACLFIILVVFGCVMVFS 197


>UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+
           antiporter, CaCA family - Parvibaculum lavamentivorans
           DS-1
          Length = 350

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 26/68 (38%), Positives = 40/68 (58%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +     V D++ GL+++A GTSLPE  +SV+   + +  M + N IGSN  +IL  LG
Sbjct: 223 TEIAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILG 282

Query: 398 LPWLVKSL 405
           +  L+  L
Sbjct: 283 VTALIAPL 290



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 24/65 (36%), Positives = 34/65 (52%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +     V   +  LTI+A GTS PE + S+     G   + + N +GSN  +I L LG
Sbjct: 27  TALAARYGVSPLLIALTIVAFGTSAPELLVSIRAALAGSPGIALGNVVGSNIANIFLILG 86

Query: 398 LPWLV 402
           LP L+
Sbjct: 87  LPALI 91



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 21/72 (29%), Positives = 38/72 (52%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I +   ++  + G + +A  +S PEL  + +  F    D+ VG ++GS + N+LA+    
Sbjct: 225 IAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILGVT 284

Query: 177 ALFAGAVIELDW 188
           AL A   I+ D+
Sbjct: 285 ALIAPLPIDPDF 296



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 6/142 (4%)

Query: 94  LALYCFLLLGSV----CEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGT 149
           + +Y +L+ G V    C D+ V     +  R  ++  +   T +A  +S+PEL ++    
Sbjct: 2   IEMYAYLIGGLVILLVCGDFLVRGATALAARYGVSPLLIALTIVAFGTSAPELLVSIRAA 61

Query: 150 FVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTL 209
                 + +G VVGS + N+  +    AL     I     +V  + ++       LI+  
Sbjct: 62  LAGSPGIALGNVVGSNIANIFLILGLPALI--YPIACTGRTVPHNMIVMMAASVLLIVLC 119

Query: 210 LDDKIYWHEALLLVLMYTFYIL 231
               + + + +LL+ + T Y++
Sbjct: 120 FVGTLSFWQGVLLISLLTAYLV 141


>UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;
           n=1; Plesiocystis pacifica SIR-1|Rep: K+-dependent
           Na+/Ca+ exchanger protein - Plesiocystis pacifica SIR-1
          Length = 325

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 25/59 (42%), Positives = 38/59 (64%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L     + GLTI+AAGTSLPE V+SV+ + +G   + ++N +GSN F++   LG   L+
Sbjct: 209 LGASQRVVGLTIVAAGTSLPELVTSVIASVRGRDDIALTNVLGSNIFNVFGILGTTTLI 267



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 28/68 (41%), Positives = 39/68 (57%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +   L V  ++ GLTI+AAGTS+PE V S      G   + ++N IGSN F+I   +G
Sbjct: 27  TSLAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIALANVIGSNIFNIAAIVG 86

Query: 398 LPWLVKSL 405
           +  LV  L
Sbjct: 87  VAALVAPL 94



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + + L ++  + G T +AA +S PEL ++       E D+ +  V+GS +FN+ A+    
Sbjct: 29  LAQLLRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIALANVIGSNIFNIAAIVGVA 88

Query: 177 ALFA-----GAVIELDW 188
           AL A     G  + L+W
Sbjct: 89  ALVAPLRVLGNSVRLEW 105



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 4/124 (3%)

Query: 68  AAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDI 127
           A  L  P  G  R  +   F  L   L +   +L GSV     V     +   L  +  +
Sbjct: 160 AEALPAPLGGELRGAKAWLFSGLGLVLGMALLVLGGSV----LVNGASALALGLGASQRV 215

Query: 128 AGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187
            G T +AA +S PEL  + + +     D+ +  V+GS +FNV  +     L A   ++ +
Sbjct: 216 VGLTIVAAGTSLPELVTSVIASVRGRDDIALTNVLGSNIFNVFGILGTTTLIAPVAVDPE 275

Query: 188 WWSV 191
             SV
Sbjct: 276 LVSV 279


>UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+
           exchanger related-protein - Pseudomonas stutzeri (strain
           A1501)
          Length = 361

 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 28/60 (46%), Positives = 36/60 (60%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +P  I GLT++A GTS PE   SV  +  G G + + N IGSN  +ILL LGL  L+  L
Sbjct: 36  IPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIAPL 95



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 22/54 (40%), Positives = 35/54 (64%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           L + + + GLT++A GTS+PE  +SVL   +G   + + N +GS  F++LL LG
Sbjct: 207 LGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLVLG 260



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 22/68 (32%), Positives = 35/68 (51%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           +  R  I   I G T +A  +S+PE  ++   +    GD+ VG V+GS + N+L +    
Sbjct: 30  LASRFGIPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLS 89

Query: 177 ALFAGAVI 184
           AL A  V+
Sbjct: 90  ALIAPLVV 97



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 3/112 (2%)

Query: 62  ERNCTPAAILEFPSD-GLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICER 120
           +R   PA   EF ++ G     +   ++     + L   LL+G    +  +     +   
Sbjct: 149 KREKAPAGDDEFATEFGPDESDKPFAWVFQLLLILLGLGLLVGG--SNLLIEGAVGLARA 206

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           L ++  + G T +A  +S PEL  + +     E D+ VG VVGS +FN+L V
Sbjct: 207 LGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLV 258


>UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa
           (japonica cultivar-group)|Rep: Os11g0148000 protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 293

 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 3/139 (2%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L  F +L +    +F PA+  +  RL ++  +A  T +A  + +P+ F +        
Sbjct: 73  LLLLHFRVLAAAAGTHFSPAVSRLAARLRLSPSMAAVTLLALGNGAPDAFASAAALGGAG 132

Query: 154 G--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLD 211
           G    G+ A++ +  F    V    AL A A   +   S  RD   Y      L    L 
Sbjct: 133 GMRRAGLAAILSAGAFVSAFVVGAVALIA-APFAVPPASFARDVFFYLLAASGLFYIYLS 191

Query: 212 DKIYWHEALLLVLMYTFYI 230
            +IY  +A+ LVL Y F++
Sbjct: 192 AEIYLWQAIGLVLFYVFFV 210


>UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2;
           Pichia stipitis|Rep: Sodium/calcium exchanger protein -
           Pichia stipitis (Yeast)
          Length = 686

 Score = 54.0 bits (124), Expect = 7e-06
 Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 2/132 (1%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
           F+ LG    DY  P +  I + L ++ +++G T +A  + SP++           G L +
Sbjct: 62  FISLGLTASDYLCPNLYTISKFLKLSDNLSGLTLLALGNGSPDVLSTFKAMSFGSGSLAI 121

Query: 159 GAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHE 218
             ++G+++F    V  C A+     +++      RD + Y      LI TL+   +    
Sbjct: 122 SELMGASLFVTTVVIGCIAIV--HPLKVPRRLFVRDTIFYLMIACLLIFTLVRQSLTLPI 179

Query: 219 ALLLVLMYTFYI 230
           +++LV  Y  Y+
Sbjct: 180 SIILVSSYVLYV 191



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FI+ +TWI   +  +  I+  +    ++ D I G+T+ A G S+ + +S+  + K G   
Sbjct: 534 FIVSVTWIAIFATEIIAILKSISIIYSLSDDILGVTVFALGNSIGDLISNFTIAKMGMPA 593

Query: 379 MGISNSIGSNTFDILLCLGLPWLV 402
           M +   +G      L  LG+  L+
Sbjct: 594 MALGACLGGPLLS-LCSLGMSGLI 616



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 20/65 (30%), Positives = 36/65 (55%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L + D+++GLT+LA G   P+ +S+      G G++ IS  +G++ F   + +G   +V 
Sbjct: 84  LKLSDNLSGLTLLALGNGSPDVLSTFKAMSFGSGSLAISELMGASLFVTTVVIGCIAIVH 143

Query: 404 SLFYP 408
            L  P
Sbjct: 144 PLKVP 148


>UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein;
           n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
           exchanger protein - Tetrahymena thermophila SB210
          Length = 602

 Score = 53.6 bits (123), Expect = 9e-06
 Identities = 36/179 (20%), Positives = 81/179 (45%), Gaps = 5/179 (2%)

Query: 57  GIVE-IERNCTPAAILEFPSDGLTRFQRQHGFI-LLHCFLALYCFLLLGSVCEDYFVPAI 114
           G+ E +++NCT  +++ F      +       + LL   + L  F +L S  E Y  PA+
Sbjct: 20  GVCEYVDQNCTAESLVRFSYFYFCQVSENIIVLDLLTVLVPLMAFHMLSSTAESYLSPAL 79

Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG--DLGVGAVVGSAVFNVLAV 172
               + L ++  +AG T +A  + +P++    +      G   + +G++ G+ +F V   
Sbjct: 80  AKCSKILRLSESVAGVTLLALGNGAPDVITAIIAGGDDNGGISIAIGSIFGAGLF-VTTA 138

Query: 173 PACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
                +F G  I++D  +  RD + Y      +++  +  K+    + + + +Y  +++
Sbjct: 139 TLSAVIFHGKNIKIDKKTFMRDMVFYLLGCLVILVYAIIGKVNIIMSSIFMSIYLIFLV 197



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 17/88 (19%), Positives = 44/88 (50%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F++ + +I +++ ++   I        +  +  GLT+LA G S  +  ++  ++K G+
Sbjct: 435 LAFVISVAYISTIAQILIDFIQFFQILSGINQTFLGLTLLAYGNSSGDFFTNTQLSKMGY 494

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVKS 404
           G M ++       F++ +  G   ++++
Sbjct: 495 GVMAMTGCFAGQGFNLYIGFGFALVMQT 522


>UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=8; Bacteroidales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 317

 Score = 53.6 bits (123), Expect = 9e-06
 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 3/91 (3%)

Query: 311 RHSIYPLTFIMCITWIGSVSY---LVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVS 367
           R    PL+ IM I  + ++ +   L      ++   + V +S+  +TI+A GTSLPE V+
Sbjct: 165 RQFALPLSIIMVIGGLVALVFGGDLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPELVT 224

Query: 368 SVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +++   +    M I N +GSN F+ILL LG+
Sbjct: 225 TLVAAIKKRPGMAIGNIVGSNLFNILLILGV 255



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 1/80 (1%)

Query: 326 IGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSI 385
           +G  ++L     ++      + D + GLT+LA GTS PE   S++   +G   + I N I
Sbjct: 16  VGGANFLTDGAASIA-KRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVI 74

Query: 386 GSNTFDILLCLGLPWLVKSL 405
           GSN F+IL  +G+  L+  L
Sbjct: 75  GSNIFNILAIVGITALIMPL 94



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 20/62 (32%), Positives = 36/62 (58%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I +R  ++  + G T +A  +S+PEL ++ +       D+ +G V+GS +FN+LA+    
Sbjct: 29  IAKRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVIGSNIFNILAIVGIT 88

Query: 177 AL 178
           AL
Sbjct: 89  AL 90



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 18/65 (27%), Positives = 32/65 (49%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV    ++  R+ ++  +   T +A  +S PEL    V        + +G +VGS +F
Sbjct: 188 DLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPELVTTLVAAIKKRPGMAIGNIVGSNLF 247

Query: 168 NVLAV 172
           N+L +
Sbjct: 248 NILLI 252


>UniRef50_Q8MYP5 Cluster: Na/ca exchangers protein 2, isoform a;
           n=7; Caenorhabditis|Rep: Na/ca exchangers protein 2,
           isoform a - Caenorhabditis elegans
          Length = 975

 Score = 53.6 bits (123), Expect = 9e-06
 Identities = 32/117 (27%), Positives = 64/117 (54%), Gaps = 4/117 (3%)

Query: 292 VLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSIT 351
           VLT P +L  +ATIP   +       TF++ I  IG ++ +V  + +  G  + + D++T
Sbjct: 782 VLTVPWKLT-FATIPPTDYFGGW--ATFVVAIFMIGVLTAVVGDLASQFGCWVGLKDAVT 838

Query: 352 GLTILAAGTSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
            ++ +A GTS+P+  +S V   +  +    + N  GSN  ++ L +G+ W + ++++
Sbjct: 839 AISFVALGTSVPDTFASKVSAVQDKYADNAVGNVTGSNAVNVFLGIGIAWSMAAIYH 895



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 4/71 (5%)

Query: 112 PAIEIICERLNIASD-IAGATFMAAASSSPELFINCVGTFVT---EGDLGVGAVVGSAVF 167
           P ++ +  ++ I +D ++  T MA  SS+PE+ ++ +         GDLG   +VGSA F
Sbjct: 99  PGLDPMAVQVRIWNDTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAF 158

Query: 168 NVLAVPACCAL 178
           N+  + A C +
Sbjct: 159 NLFMIIAICVV 169



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 16/54 (29%), Positives = 34/54 (62%), Gaps = 3/54 (5%)

Query: 348 DSITGLTILAAGTSLPEAVSSVL-VTKQGH--GTMGISNSIGSNTFDILLCLGL 398
           D+++ LT++A G+S PE + S++ V  +G   G +G +  +GS  F++ + + +
Sbjct: 113 DTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAI 166


>UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2;
           Methanosarcina|Rep: Sodium/calcium exchanger protein -
           Methanosarcina acetivorans
          Length = 418

 Score = 53.6 bits (123), Expect = 9e-06
 Identities = 23/62 (37%), Positives = 40/62 (64%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +P+++ G++++A GTSLPE + ++   + G+ ++ + N IGSN  + LL LG   LV 
Sbjct: 303 LEIPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIGSNITNTLLILGCSGLVN 362

Query: 404 SL 405
            L
Sbjct: 363 PL 364



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 2/124 (1%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D FV +   I ER  ++  I G T ++  +S PEL      +      + +G V+GS + 
Sbjct: 21  DLFVMSSSWIAERFGVSEFIIGLTLVSIGTSVPELASALTASLEHASGIVIGDVLGSNIA 80

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  + +  AL +   +  +   + RD  +        +L++LD +I   EAL+ +L Y 
Sbjct: 81  NIGLIVSTAALLSN--VRTEELMLRRDGYIMLFSLFIFLLSILDFRISRLEALIFLLFYF 138

Query: 228 FYIL 231
            Y+L
Sbjct: 139 VYLL 142



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 18/66 (27%), Positives = 37/66 (56%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + +   V + I GLT+++ GTS+PE  S++  + +    + I + +GSN  +I L +   
Sbjct: 30  IAERFGVSEFIIGLTLVSIGTSVPELASALTASLEHASGIVIGDVLGSNIANIGLIVSTA 89

Query: 400 WLVKSL 405
            L+ ++
Sbjct: 90  ALLSNV 95



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 3/119 (2%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFN 168
           YF+         L I   + G + +A  +S PEL +           + +G V+GS + N
Sbjct: 291 YFIEQSIFFALLLEIPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIGSNITN 350

Query: 169 VLAVPACCALFAG-AVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMY 226
            L +  C  L     V ++  + +T    M       L+      +I   E ++L+L+Y
Sbjct: 351 TLLILGCSGLVNPLTVTKISIYYITP--FMLFISLLLLLFIRTGWRIKRTEGVILLLLY 407


>UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependent
           Na/Ca exchanger NCKX4, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to K-dependent Na/Ca
           exchanger NCKX4, partial - Strongylocentrotus purpuratus
          Length = 76

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 24/58 (41%), Positives = 36/58 (62%)

Query: 62  ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICE 119
           E NCT   I +FP    T  QR+ G ++++  ++LY    +G VC  YFVP++EI+CE
Sbjct: 19  EDNCTVRGISKFPRGVFTNEQRKGGALVVNFLVSLYLCGAIGYVCAAYFVPSLEILCE 76


>UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Clostridium oremlandii OhILAs|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Clostridium oremlandii OhILAs
          Length = 310

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 6/116 (5%)

Query: 309 RHRHSIYPLTFIMCITWIGSV--SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAV 366
           R    +  + F + +  IG V   Y +      +   L    +  GLT++A GTSLPE +
Sbjct: 159 RQSMDLIHILFYLVLGIIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSLPELI 218

Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTDLYFI 422
           + ++   + +  + + N IGSN F+IL  L     V SL  P    +H + DL F+
Sbjct: 219 TCLVACHKKNDDIAVGNIIGSNIFNILFVLS----VSSLISPIAFSSHLIIDLAFM 270



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 3/132 (2%)

Query: 101 LLGSVCEDYFVPAIEI-ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           ++G V   Y++    + I   L  +    G T +A  +S PEL    V       D+ VG
Sbjct: 175 IIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSLPELITCLVACHKKNDDIAVG 234

Query: 160 AVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEA 219
            ++GS +FN+L V +  +L   + I      +     M        I +    KI   E 
Sbjct: 235 NIIGSNIFNILFVLSVSSLI--SPIAFSSHLIIDLAFMLLFTFLLFIFSYTHKKISRLEG 292

Query: 220 LLLVLMYTFYIL 231
            +L+++Y FY +
Sbjct: 293 FVLMMLYLFYFV 304



 Score = 43.2 bits (97), Expect = 0.013
 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 317 LTFIMCITWIGSVSYLVAWII---TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           + FI+ I    ++     W+I   + +   L +   I GLT++A GTS PEA  +++ + 
Sbjct: 4   IPFIVLIVSFLAIIKSADWLIDASSALALYLGISPLIVGLTVVAFGTSAPEASVNIIASF 63

Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           Q    + I N  GSN  +I + +G+  L+ ++
Sbjct: 64  QKKSEIVIGNITGSNIINIGIVIGITSLIYTI 95


>UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1;
           Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein
           - Haloarcula marismortui (Halobacterium marismortui)
          Length = 335

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 109 YFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV-TEGDLGVGAVVGSAVF 167
           YF  A E + +   +   + GA  +A  SS PE+    + T +  E  LGVGA+VGSA+F
Sbjct: 24  YFERAAERLSKYYGLPVAVHGAIVVAVGSSFPEISSVVISTVIHDEFSLGVGAIVGSAIF 83

Query: 168 NVLAVPACCAL 178
           N+L +PA  AL
Sbjct: 84  NLLVIPALAAL 94



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           +G   + P  + GLT++AAGTSLP+A  SV   K       ++N +GSNTF++L+ +
Sbjct: 205 LGVIFDTPTFLWGLTVIAAGTSLPDAFVSVRAAKDDDSVTSLTNVLGSNTFNLLVAI 261


>UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 309

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 25/58 (43%), Positives = 35/58 (60%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           V   L V D+  GLTI+A GTSLPE  +SV+   +    + + N +GSN F++L  LG
Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILG 249



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 19/64 (29%), Positives = 35/64 (54%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + + L ++    G T +A  +S PEL  + +  +  + ++ VG +VGS +FNVL +    
Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGAT 251

Query: 177 ALFA 180
           A+ A
Sbjct: 252 AVIA 255



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 22/59 (37%), Positives = 34/59 (57%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L +P  + GLT++  GTS PE + SV    +G   + + N +GSN  +ILL  G+  L+
Sbjct: 31  LGLPPLLIGLTVVGFGTSTPELLVSVDAALRGVPDIALGNILGSNIANILLIGGITSLI 89



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 8/118 (6%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + +RL +   + G T +   +S+PEL ++         D+ +G ++GS + N+L +    
Sbjct: 27  LAQRLGLPPLLIGLTVVGFGTSTPELLVSVDAALRGVPDIALGNILGSNIANILLIGGIT 86

Query: 177 AL---FAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           +L     G  + L W    RD  +       L   LL  ++     L+L+L    Y++
Sbjct: 87  SLIWPIRGKPVGL-W----RDLTVMILATLALTPILLGGQVIRVVGLVLLLSLVAYLV 139


>UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21;
           Bacteria|Rep: Na+/Ca+ antiporter, CaCA family -
           Roseiflexus sp. RS-1
          Length = 367

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 24/57 (42%), Positives = 37/57 (64%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           V + + GLTI+A GTSLPE  +S++   +G   + + N +GSN F++L  LGL  +V
Sbjct: 210 VSELVIGLTIVAVGTSLPEIATSIVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVV 266



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 22/60 (36%), Positives = 34/60 (56%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186
           + G T +A  +S PE+  + V     E D+ VG VVGS +FN+L+V    ++ A A I +
Sbjct: 214 VIGLTIVAVGTSLPEIATSIVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVVAPAGISV 273



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQG-HGT-MGISNSIGSNTFDILLCLGL 398
           L +   + GLT++A GTS PE   S+     G +G  + + N +GSN  ++LL LG+
Sbjct: 34  LGISPLVVGLTVVAFGTSAPELAVSIQSALSGPNGADVALGNVVGSNIANVLLILGI 90



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 7/118 (5%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFV--TEGDLGVGAVVGSAVFNVLAVPACCAL 178
           L I+  + G T +A  +S+PEL ++           D+ +G VVGS + NVL +    A 
Sbjct: 34  LGISPLVVGLTVVAFGTSAPELAVSIQSALSGPNGADVALGNVVGSNIANVLLILGISAA 93

Query: 179 FAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLL---VLMYTFYILEK 233
               V++     +  D  +       + +  LD  I   + L+L   ++ YT + + +
Sbjct: 94  ITPLVVQQQ--LIRLDVPLMIGISVVVFVMALDGTISRIDGLILFAGIIAYTVFAIRQ 149


>UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23;
           Cyanobacteria|Rep: Ca2+/Na+ antiporter - Synechococcus
           sp. (strain WH7803)
          Length = 372

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 3/119 (2%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L ++  + G T ++A +S PEL  + V       DL +G VVGS + N L V    A+ A
Sbjct: 205 LGVSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDLAIGNVVGSNLLNQLLVLGASAVAA 264

Query: 181 --GAVIELDWWSVTRDC-MMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINP 236
             GA +++    + RD  +M       L +     +I   E  +LV +Y FY+++++ P
Sbjct: 265 AGGAGLQVSPMLIARDLPVMVLAALACLPIFWTRGQITRLEGGILVTLYVFYVVDQVLP 323



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 26/78 (33%), Positives = 45/78 (57%)

Query: 320 IMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           ++ I  +G  S ++    +     L V  ++ GLTI++AGTS+PE ++S++   +G   +
Sbjct: 181 VVGIVLLGVGSRVLVHGASAAATFLGVSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDL 240

Query: 380 GISNSIGSNTFDILLCLG 397
            I N +GSN  + LL LG
Sbjct: 241 AIGNVVGSNLLNQLLVLG 258



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 23/60 (38%), Positives = 36/60 (60%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +P  + GLT+++ GTS PE   S+    QG   + +SN +GSN F++++ LG   LV  L
Sbjct: 38  IPQLVIGLTVVSFGTSAPELFVSLSSVTQGFDALAVSNVVGSNIFNVMVVLGSSALVMPL 97



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 7/138 (5%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           LL C   L    LL    E  FV     +     I   + G T ++  +S+PELF++   
Sbjct: 5   LLSCLEVLVGIALLFGGGE-LFVQGAVTLSLIFGIPQLVIGLTVVSFGTSAPELFVSL-- 61

Query: 149 TFVTEG--DLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
           + VT+G   L V  VVGS +FNV+ V    AL     +E     V RD  +       + 
Sbjct: 62  SSVTQGFDALAVSNVVGSNIFNVMVVLGSSALVMPLRVESR--LVRRDVPLLIAVSAAVW 119

Query: 207 LTLLDDKIYWHEALLLVL 224
                 ++ W   + L+L
Sbjct: 120 GMASAGRVTWQAGIALLL 137


>UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Roseobacter sp. CCS2|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Roseobacter sp. CCS2
          Length = 326

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)

Query: 341 GDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPW 400
           G  + VP+++ G+T++A GTSLPE  + +   ++    + + N IGSNTF+IL  + L  
Sbjct: 204 GSAIGVPEAVIGMTVVAFGTSLPELSTCIAAARKQSVGLILGNIIGSNTFNILSIIALTA 263

Query: 401 LVKSL 405
            +K L
Sbjct: 264 AIKPL 268



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 21/46 (45%), Positives = 30/46 (65%)

Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           G TI++ GTS+PE  +SV    QG+  + + N +GSN  +ILL LG
Sbjct: 50  GATIVSFGTSVPELFTSVNANLQGYPGISLGNVLGSNVANILLVLG 95



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F+L    +A   +LL+     D+ V A   + ER  ++    GAT ++  +S PELF + 
Sbjct: 10  FVLAAGAMAFGLYLLIKG--GDWTVDAAVFVAERTGLSPLFIGATIVSFGTSVPELFTSV 67

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                    + +G V+GS V N+L V    A      +  D   + +D  M       ++
Sbjct: 68  NANLQGYPGISLGNVLGSNVANILLVLGATAFV--FKVTADPKHLAKDLAMMLFATAIMV 125

Query: 207 LTLLDDKIYWHEALLL-VLMYTFYILE 232
             +L D       L++  ++ TF + +
Sbjct: 126 YGMLTDSFSQVFGLIMFAILVTFVVYQ 152


>UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; Erythrobacter|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Erythrobacter sp.
           NAP1
          Length = 328

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 23/52 (44%), Positives = 35/52 (67%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           VP+++ GLT++A GTSLPE  +S+    +G   + I N +GSN ++ILL  G
Sbjct: 197 VPETVIGLTVVAIGTSLPELAASIAAALRGKSGLAIGNVLGSNIYNILLIGG 248



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 24/63 (38%), Positives = 34/63 (53%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + + L V    TGL I+   TS+PE V+SV  +  G   +   N +GSN  + LL LG+ 
Sbjct: 29  IAEKLGVSTLFTGLVIVGFATSMPEMVASVQASLAGSPEIAWGNIVGSNLANTLLILGVS 88

Query: 400 WLV 402
            LV
Sbjct: 89  ALV 91


>UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Rep:
           F7G19.17 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 546

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 25/81 (30%), Positives = 45/81 (55%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           + FIM + WI +++  +   +  +G  L +P ++ GLT+LA G S+ + V+ V V K G 
Sbjct: 391 VAFIMSVFWISTIAGELLNCLAALGTLLKLPPALLGLTVLAWGNSVGDLVADVAVAKAGR 450

Query: 377 GTMGISNSIGSNTFDILLCLG 397
             M ++       F++L+ LG
Sbjct: 451 PAMAMAGCFAGPMFNMLVGLG 471



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 1/137 (0%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L  F +L    + +F      + +RLN++  +A  T +A  + +P++F +       +
Sbjct: 99  LILLHFYILIKTAQTHFSTVTTKLADRLNLSPSMAAVTLLALGNGAPDVFASVAALRGGQ 158

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
              G GA++ +  F    V    A++A A   +D  S  RD + Y      L    L  +
Sbjct: 159 YRTGFGAILSAGTFVSAFVVGFVAIYA-APFPVDAASFVRDVLFYLIAALFLFYVYLSGE 217

Query: 214 IYWHEALLLVLMYTFYI 230
           I+  +A+  V  Y F++
Sbjct: 218 IFVWQAIGFVGFYIFFV 234



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 336 IITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTF 390
           + T + D LN+  S+  +T+LA G   P+  +SV   + G    G    + + TF
Sbjct: 118 VTTKLADRLNLSPSMAAVTLLALGNGAPDVFASVAALRGGQYRTGFGAILSAGTF 172


>UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_5,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 536

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 3/175 (1%)

Query: 59  VEIERNCTPAAILEFPSDGLTRFQRQHGFILLHC-FLALYCFLLLGSVCEDYFVPAIEII 117
           V ++ NC    I +F      +       ++L    L  + F  L    +DY  PA+  I
Sbjct: 18  VYVKENCNDQEIFKFTHYYFCQLDENWVILILIAPLLFFFLFNFLARTVDDYLSPAVTFI 77

Query: 118 CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL-GVGAVVGSAVFNVLAVPACC 176
            E   ++   AG T +A A+  P+ F   + +   +G L  VG++ GS +     V    
Sbjct: 78  AEYFKMSQTFAGVTLIAFANGVPDFFCAVLASQDDDGILIAVGSIFGSCLCMTTLVFGAV 137

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
            LF+G +I+       RD +        L++     +I  + A+    +Y  YI+
Sbjct: 138 ILFSG-IIKAQKVPFIRDILFNGVAIFLLMVFAFIGQINHYMAIGFCSLYLVYIV 191


>UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=17; Rhodobacterales|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Silicibacter
           pomeroyi
          Length = 319

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 22/69 (31%), Positives = 43/69 (62%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           ++L+    +++  T  V +++ GLT++A GTSLPE  ++V+   +    + + N IGSN 
Sbjct: 192 AHLLVENASIIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNM 251

Query: 390 FDILLCLGL 398
           F++L  +G+
Sbjct: 252 FNLLAIIGV 260



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 27/62 (43%), Positives = 38/62 (61%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L VP  I  LTI+A GTS PE + S+    +    + + N +GSNT +ILL LG+P L+ 
Sbjct: 32  LGVPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALLA 91

Query: 404 SL 405
           +L
Sbjct: 92  TL 93



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 19/64 (29%), Positives = 33/64 (51%)

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           II     ++  + G T +A  +S PEL    +     + D+ +G V+GS +FN+LA+   
Sbjct: 201 IIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNMFNLLAIIGV 260

Query: 176 CALF 179
             +F
Sbjct: 261 ATMF 264



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 21/61 (34%), Positives = 30/61 (49%)

Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALF 179
           RL + + I   T +A  +S+PEL I+          + +G VVGS   N+L V    AL 
Sbjct: 31  RLGVPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALL 90

Query: 180 A 180
           A
Sbjct: 91  A 91


>UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Desulfovibrio desulfuricans
           G20|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Desulfovibrio desulfuricans (strain G20)
          Length = 339

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/76 (39%), Positives = 44/76 (57%)

Query: 330 SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNT 389
           S LV    T +   L V + + GLTI+A GTSLPE V+ V+ + +G   M + N IGS+ 
Sbjct: 208 SRLVVNGATAIAAWLGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMMLGNLIGSDL 267

Query: 390 FDILLCLGLPWLVKSL 405
           F+    LG+  L++ L
Sbjct: 268 FNFAGVLGITALLRPL 283



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 21/54 (38%), Positives = 35/54 (64%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           + + + + GLTI+A GTSLPE + S      G+ ++ ++N +GSN F++ L LG
Sbjct: 34  VGISELVIGLTIVALGTSLPEFLVSFTAAVTGYSSISVANVVGSNIFNLGLILG 87



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 93  FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           FLAL   LL      D  V     +  R+ I+  + G T +A  +S PE  ++       
Sbjct: 8   FLALGGLLLWFGA--DRLVEGASALARRVGISELVIGLTIVALGTSLPEFLVSFTAAVTG 65

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187
              + V  VVGS +FN+  +    A+    + E D
Sbjct: 66  YSSISVANVVGSNIFNLGLILGGVAMLRPVMPERD 100



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L ++  + G T +A  +S PEL    V +F    ++ +G ++GS +FN   V    AL  
Sbjct: 222 LGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMMLGNLIGSDLFNFAGVLGITALL- 280

Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223
              + +D  ++    +        L+L  L  ++   E LLL+
Sbjct: 281 -RPLSVDASALPNLALSVFTVLLILLLLRLRGRLGKAEGLLLL 322


>UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Prosthecochloris aestuarii DSM
           271|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Prosthecochloris aestuarii DSM 271
          Length = 334

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 5/95 (5%)

Query: 314 IYPLTFIMCITWIGSVSYLV-AWIITV----VGDTLNVPDSITGLTILAAGTSLPEAVSS 368
           I PL   + +   GSV     AW        + + LN+P    GL+I+A GTSLPE  +S
Sbjct: 174 ILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATS 233

Query: 369 VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           ++   +    + + N IGSN F+IL  LG   ++K
Sbjct: 234 LVGAIRRESEISVGNLIGSNIFNILFVLGGVSMIK 268



 Score = 46.4 bits (105), Expect = 0.001
 Identities = 24/63 (38%), Positives = 36/63 (57%)

Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           FV +   I E+LNI     G + +A  +S PEL  + VG    E ++ VG ++GS +FN+
Sbjct: 198 FVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRRESEISVGNLIGSNIFNI 257

Query: 170 LAV 172
           L V
Sbjct: 258 LFV 260



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 323 ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV-TKQGHGTMGI 381
           + +IG+  +L+   + + G    +   + GLT++A GTS+PE V S      +   ++ +
Sbjct: 24  LLFIGA-EWLIRGSVDLAGK-FGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSISL 81

Query: 382 SNSIGSNTFDILLCLGLPWLV 402
            N IGSN  +I L LGL  L+
Sbjct: 82  GNVIGSNITNIGLILGLSALI 102


>UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1;
           uncultured marine bacterium EB0_49D07|Rep: K+-dependent
           Na+/Ca+ antiporter - uncultured marine bacterium
           EB0_49D07
          Length = 313

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 23/53 (43%), Positives = 35/53 (66%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           L VP  I GLTI+A GTSLPE  ++++  ++G   M + N IGSN F+++  +
Sbjct: 192 LGVPQLIIGLTIIALGTSLPELAATIVALRKGKHQMVVGNIIGSNVFNLVFII 244



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 6/130 (4%)

Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           FV    +I + + I+  + G T +A  +S+PE+F+          ++ +G  +GS + N+
Sbjct: 24  FVDHASVIAKHMGISDLVIGLTLIAFGTSAPEIFVGISSIINQNEEIALGTAIGSNISNI 83

Query: 170 LAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEAL--LLVLMYT 227
             +     L+     +   W+     + +      L LTL+D KI ++E++  + +LM  
Sbjct: 84  ALIFGVSCLYLTEPSKTQLWNF----VPFGLSVVLLGLTLVDGKISFNESMGFVGILMIF 139

Query: 228 FYILEKINPL 237
            ++L K + L
Sbjct: 140 MFVLFKTDGL 149



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 19/64 (29%), Positives = 33/64 (51%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           +V+   + + D + GLT++A GTS PE    +      +  + +  +IGSN  +I L  G
Sbjct: 29  SVIAKHMGISDLVIGLTLIAFGTSAPEIFVGISSIINQNEEIALGTAIGSNISNIALIFG 88

Query: 398 LPWL 401
           +  L
Sbjct: 89  VSCL 92



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           L +   I G T +A  +S PEL    V     +  + VG ++GS VFN++ +      F 
Sbjct: 192 LGVPQLIIGLTIIALGTSLPELAATIVALRKGKHQMVVGNIIGSNVFNLVFIIPMIGFFG 251

Query: 181 GA-----VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
                  V++ D++ +    M++      L        I+    ++L+  Y  YI
Sbjct: 252 SVELSPMVMQRDFYILLVLSMVFILLAVVLTKLQFRKNIFSISGVVLIASYVLYI 306


>UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative,
           expressed; n=6; Magnoliophyta|Rep: Magnesium/proton
           exchanger, putative, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 523

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 3/108 (2%)

Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
           +L+A +P     H    + FI  + +I  ++Y V  I   +     V   +   T LAAG
Sbjct: 339 MLFAFVPPYEIAHGW--IAFICSLIFISGIAYGVTKITDQISCVTGVSPYVIAFTALAAG 396

Query: 360 TSLPEAVSS-VLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLF 406
           TS P+ V+S +   +Q      I+N   SN+ +I + +G+PWLV +++
Sbjct: 397 TSWPDLVASKIAAERQITADSAITNITCSNSVNIYVGIGVPWLVDTMY 444



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 13/117 (11%)

Query: 127 IAGATFMAAASSSPELFINCVGTF-----VTEGDLGVGAVVGSAVFNVLAVPACCALF-- 179
           IA    +A  +S P++ +  +        +T G LG G +VGSA F++  + A C +   
Sbjct: 88  IADVALLAFGTSFPQISLATIDAIRNLGQLTAGGLGPGTLVGSAAFDLFPIHAVCVVMPR 147

Query: 180 AGA---VIELDWWSVTRDCMMYXXXXXXLILTLLDDKI--YWHEALLLVLMYTFYIL 231
           AG+   + +L  W V      +      +IL +   ++   W EALL VL Y   +L
Sbjct: 148 AGSKKKISDLGVWLVELFWSFWAYIWLYIILEVWTPRVITLW-EALLTVLQYGLLLL 203


>UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Pseudomonas syringae group|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Pseudomonas syringae pv. phaseolicola (strain 1448A /
           Race 6)
          Length = 343

 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 32/87 (36%), Positives = 44/87 (50%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L   LLL +      V A  +I   L ++  I G T +A  +S P L  + +  F  E
Sbjct: 162 LMLAAGLLLLTAGGHLLVDASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGE 221

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFA 180
            D+ VG V+GS +FN+L V    ALFA
Sbjct: 222 RDIAVGNVIGSNLFNLLGVLGVTALFA 248



 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           V+   L + + I GLTI+A GTSLP  ++S++   +G   + + N IGSN F++L  LG+
Sbjct: 184 VIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGV 243

Query: 399 PWLVKSLFYPSTPENHWVTDL 419
             L   +    +P N  V DL
Sbjct: 244 TALFAPVPLTVSP-NAMVFDL 263



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 18/52 (34%), Positives = 31/52 (59%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           + G T +A  +S+P++ ++    F    D+ VG+V+G  +FNVL +   CAL
Sbjct: 32  LIGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLCAL 83



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           + GLT++A GTS P+   S+      +  + + + IG N F++L+ LGL  L+
Sbjct: 32  LIGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGLCALI 84


>UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Desulfuromonas acetoxidans DSM
           684|Rep: K+-dependent Na+/Ca+ exchanger related-protein
           - Desulfuromonas acetoxidans DSM 684
          Length = 314

 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 3/67 (4%)

Query: 335 WIIT---VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFD 391
           W+++   ++  ++ + +   G+TI+A GTSLPE  +S++   +G   + I N IGSN F+
Sbjct: 188 WMVSSAVIIARSIGLSELFIGMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIFN 247

Query: 392 ILLCLGL 398
           IL  LG+
Sbjct: 248 ILFVLGV 254



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 23/78 (29%), Positives = 40/78 (51%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           ++ V +  II   + ++    G T +A  +S PEL  + +     E D+ +G V+GS +F
Sbjct: 187 NWMVSSAVIIARSIGLSELFIGMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIF 246

Query: 168 NVLAVPACCALFAGAVIE 185
           N+L V   C +F    +E
Sbjct: 247 NILFVLGVCPIFQPIAVE 264



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 22/59 (37%), Positives = 34/59 (57%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408
           I G+TI++  TS+PE + S+L   +G   + + N +GSN  +I L LG   L+  L  P
Sbjct: 39  IIGMTIVSFATSMPEMMVSLLAVGKGSSDIAVGNIVGSNIANIGLILGTSALLMPLNVP 97



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 18/71 (25%), Positives = 33/71 (46%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V     +     +   I G T ++ A+S PE+ ++ +       D+ VG +VGS + 
Sbjct: 20  DFLVDGSSRLALSFGVRPLIIGMTIVSFATSMPEMMVSLLAVGKGSSDIAVGNIVGSNIA 79

Query: 168 NVLAVPACCAL 178
           N+  +    AL
Sbjct: 80  NIGLILGTSAL 90


>UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Hyphomonas neptunium ATCC
           15444|Rep: K+-dependent Na+/Ca+ exchanger
           related-protein - Hyphomonas neptunium (strain ATCC
           15444)
          Length = 339

 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 25/60 (41%), Positives = 39/60 (65%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + + +++ GLTI+A GTSLPE  +SV+   +    + + N IGSN F+IL  LG+  LV+
Sbjct: 201 IGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILGITALVQ 260



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           V   LN+ + + GLT++  GTS+PE V+S+    QG   + I N +GSN  ++LL L +
Sbjct: 27  VARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVLLVLAI 85



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 20/62 (32%), Positives = 35/62 (56%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           +  ++ I+  + G T +A  +S PEL  + V  F  + D+ +G V+GS +FN+L +    
Sbjct: 197 LARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILGIT 256

Query: 177 AL 178
           AL
Sbjct: 257 AL 258



 Score = 36.7 bits (81), Expect = 1.2
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +++  +A   FLL   V  +  V     +  +LNI+  + G T +   +S PEL  +   
Sbjct: 1   MMYLMIAAGLFLLF--VGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQA 58

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
                  + +G VVGS + NVL V A   + +  ++
Sbjct: 59  VGQGAVGISIGNVVGSNIANVLLVLAIAVILSPIIV 94


>UniRef50_O83997 Cluster: Conserved hypothetical integral membrane
           protein; n=1; Treponema pallidum|Rep: Conserved
           hypothetical integral membrane protein - Treponema
           pallidum
          Length = 341

 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 20/52 (38%), Positives = 34/52 (65%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           VP  I   TI+A GTS+PE VS++   ++GHG + + N +G++  ++L  +G
Sbjct: 222 VPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAVGNIVGADILNVLFVVG 273



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 99  FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
           FL+LGS      +P +EI+  R  + + I  AT +A  +S PEL           G L V
Sbjct: 201 FLVLGS---RVLIPTVEIMALRAGVPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAV 257

Query: 159 GAVVGSAVFNVLAVPACCA 177
           G +VG+ + NVL V    A
Sbjct: 258 GNIVGADILNVLFVVGAAA 276



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + +++ G T+++ GT+ PEA  SV     G+  + + N+IGS   D    LGL
Sbjct: 48  ISEALLGATLVSLGTTTPEAAVSVYAALCGNADLALGNAIGSIVVDTGFILGL 100



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 23/92 (25%), Positives = 40/92 (43%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155
           L C L   +   D  V +   +  R  I+  + GAT ++  +++PE  ++         D
Sbjct: 21  LLCALYFLARSADCLVESASALSRRWGISEALLGATLVSLGTTTPEAAVSVYAALCGNAD 80

Query: 156 LGVGAVVGSAVFNVLAVPACCALFAGAVIELD 187
           L +G  +GS V +   +    AL A   + LD
Sbjct: 81  LALGNAIGSIVVDTGFILGLGALLARPGLALD 112


>UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
           n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter,
           CaCA family precursor - Ruthia magnifica subsp.
           Calyptogena magnifica
          Length = 317

 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 3/88 (3%)

Query: 318 TFIMCITWIGSV---SYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQ 374
           T+IM I  + S+   + LV W    V     V D I GL+++A GT LPE   S+    +
Sbjct: 173 TWIMLIVNLVSLISSAKLVVWGSIEVAKVFGVSDLIIGLSVVALGTGLPELAVSITSVLK 232

Query: 375 GHGTMGISNSIGSNTFDILLCLGLPWLV 402
               M I N IGSN F+ +  L +P L+
Sbjct: 233 KQYAMVIGNVIGSNLFNTIAVLAIPGLI 260



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 24/68 (35%), Positives = 37/68 (54%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T + +   +   I GL I   GTS PE + S L   +G+  + I N+IGSN F+I L LG
Sbjct: 30  TKIANIFKISPLIIGLIIFGFGTSTPEMLVSALAAIEGNTGLSIGNAIGSNIFNISLVLG 89

Query: 398 LPWLVKSL 405
           +  ++  +
Sbjct: 90  ISAIISPI 97



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           ILL     L  F+LL     D F      I     I+  I G       +S+PE+ ++ +
Sbjct: 4   ILLPIIALLSGFVLL-IWSADKFTENGTKIANIFKISPLIIGLIIFGFGTSTPEMLVSAL 62

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207
                   L +G  +GS +FN+  V    A+ +   ++ D +   ++ +        L L
Sbjct: 63  AAIEGNTGLSIGNAIGSNIFNISLVLGISAIISPIEVQGDVFK--KEWLFLMVVTLCLGL 120

Query: 208 TLLDDKIYWHEAL----LLVLMYTFYILEKINPL 237
            L D ++ + + +    LLVL + + I +  N +
Sbjct: 121 LLWDYRLDFTDGMILLSLLVLFFAYTIKQAKNKM 154


>UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like
           protein; n=1; Salinibacter ruber DSM 13855|Rep:
           K+-dependent Na+/Ca+ exchanger-like protein -
           Salinibacter ruber (strain DSM 13855)
          Length = 317

 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 23/58 (39%), Positives = 36/58 (62%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           + D LN+   + GLT++A GTSLPE  +S++ T +    M + N IGSN  ++L  +G
Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVG 257



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I + LNI   + G T +A  +S PEL  + VGT   E D+ VG V+GS + NVL V    
Sbjct: 200 ISDVLNIDHVVIGLTVVAIGTSLPELAASMVGTLKQEVDMTVGNVIGSNLLNVLFVVGTL 259

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           A+     ++ +   +    M+       + LT  D KI   E   +V+ +  +++
Sbjct: 260 AIAEPITVDPETIRLHFPVML-GFCALLVPLTWWDQKITRVEGAFMVIAFLGFMV 313



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 21/48 (43%), Positives = 29/48 (60%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           I GLT++A GTS+PE + +V     G   + I N IGSN  ++ L LG
Sbjct: 39  ILGLTVVALGTSMPEYLVNVFALISGESPLAIGNIIGSNISNVALILG 86



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           ++L+ FL     LLL    E     A  I  +   I   I G T +A  +S PE  +N  
Sbjct: 1   MILYVFLFFVGLLLLYLGAEGLIQGASSIALQ-YGIRPVILGLTVVALGTSMPEYLVNVF 59

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
                E  L +G ++GS + NV  +   CA+
Sbjct: 60  ALISGESPLAIGNIIGSNISNVALILGACAV 90


>UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
           Salinispora|Rep: Na+/Ca+ antiporter, CaCA family -
           Salinispora tropica CNB-440
          Length = 352

 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 304 TIPDCRHRHSIY-PLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSL 362
           T P  R R + + P+  ++ +  + + + L+      +   L VP  + G+T++A GTSL
Sbjct: 198 TEPTPRQRPARWEPVRTVLGLVGVLAGAQLLVVNAAAIATDLGVPQLVIGMTLVAVGTSL 257

Query: 363 PEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           PE V+++   +QG   + + N  GSN F+ L
Sbjct: 258 PELVTTIQAQRQGESDLLVGNLFGSNLFNSL 288



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 27/101 (26%), Positives = 45/101 (44%)

Query: 85  HGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFI 144
           H  I+L   L     LLL +V  D+ V     +  RL I   + G   +   +S+PEL +
Sbjct: 19  HERIMLIRILLAVAGLLLLTVAADHLVLGASRLAHRLRIRPVVVGVVVIGLGTSAPELLV 78

Query: 145 NCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIE 185
           + V     +  + +G + GS + N+  V    AL A   ++
Sbjct: 79  SGVAAARDDTSIAMGNIAGSNILNLTMVLGVAALVAKVTVK 119



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 18/67 (26%), Positives = 34/67 (50%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +   + G+ ++  GTS PE + S +   +   ++ + N  GSN  ++ + LG+  LV 
Sbjct: 55  LRIRPVVVGVVVIGLGTSAPELLVSGVAAARDDTSIAMGNIAGSNILNLTMVLGVAALVA 114

Query: 404 SLFYPST 410
            +   ST
Sbjct: 115 KVTVKST 121



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 23/68 (33%), Positives = 30/68 (44%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I   L +   + G T +A  +S PEL          E DL VG + GS +FN LA  A  
Sbjct: 235 IATDLGVPQLVIGMTLVAVGTSLPELVTTIQAQRQGESDLLVGNLFGSNLFNSLAGGAVI 294

Query: 177 ALFAGAVI 184
           A  A   +
Sbjct: 295 AFAAPTTV 302


>UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Petrotoga mobilis SJ95|Rep: Na+/Ca+ antiporter, CaCA
           family - Petrotoga mobilis SJ95
          Length = 320

 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 22/64 (34%), Positives = 41/64 (64%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           +   ++ + +S+ G+TI+A GTSLPE V++++   +    + + N +GSNTF+I   LG+
Sbjct: 199 IFAKSIGISESLIGVTIVAVGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGI 258

Query: 399 PWLV 402
             L+
Sbjct: 259 SALI 262



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 1/59 (1%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L V +   GLT++A GTS PE V ++  + +G  ++G+ N +GSN  +I L LG+ +L+
Sbjct: 32  LGVSELFAGLTVVAFGTSAPELVVTISSSIKG-ASVGLGNVLGSNVANIGLILGISFLI 89



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 2/108 (1%)

Query: 75  SDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMA 134
           ++ + + +++  +  +  F AL   +L+  +  +  V    I  + + I+  + G T +A
Sbjct: 160 NEEMKKVEKEESWAKIITFSALGLAMLI--IGGELTVSNAVIFAKSIGISESLIGVTIVA 217

Query: 135 AASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
             +S PEL    V       D+ +G +VGS  FN+ A+    AL  GA
Sbjct: 218 VGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGISALINGA 265



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           +AL  FLL+     D  +     +  +L ++   AG T +A  +S+PEL +  + + +  
Sbjct: 7   IALGIFLLIRGA--DRLIEGALGLTRKLGVSELFAGLTVVAFGTSAPELVVT-ISSSIKG 63

Query: 154 GDLGVGAVVGSAVFNV 169
             +G+G V+GS V N+
Sbjct: 64  ASVGLGNVLGSNVANI 79


>UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1;
           Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger -
           Algoriphagus sp. PR1
          Length = 312

 Score = 51.2 bits (117), Expect = 5e-05
 Identities = 22/60 (36%), Positives = 37/60 (61%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           V + + G+TI+A GTSLPE ++S++        M I N +GSN  ++L  LG+  ++K +
Sbjct: 202 VSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMNVLSILGITAIIKPI 261



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +   + GLTI+A GTS PE + SV    +G+  + + N IGSN  +I + LG    + 
Sbjct: 32  LGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDISVGNVIGSNIANIGMVLG----IS 87

Query: 404 SLFYPSTPENHWVTDLYFIRI 424
            LFYP       +   YFI +
Sbjct: 88  GLFYPILIRKSTLRFDYFITV 108



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 20/69 (28%), Positives = 34/69 (49%)

Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           V     I  +L +++ + G T +A  +S+PEL ++         D+ VG V+GS + N+ 
Sbjct: 22  VDGASAIAVKLGMSAGLIGLTIVAFGTSAPELLVSVNAALKGNSDISVGNVIGSNIANIG 81

Query: 171 AVPACCALF 179
            V     LF
Sbjct: 82  MVLGISGLF 90



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 24/116 (20%), Positives = 54/116 (46%), Gaps = 5/116 (4%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I     ++  + G T +A  +S PEL  + +     + D+ +G ++GS + NVL++    
Sbjct: 196 ISREFGVSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMNVLSILGIT 255

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK--IYWHEALLLVLMYTFYI 230
           A+     +  ++    +   ++      ++  L+  K  I + E L+L++ Y  Y+
Sbjct: 256 AIIKPIGVSDEF---LQSDFLWMIGFTLILFPLIRTKMRISFIEGLILLIGYCTYL 308


>UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter
           thermautotrophicus|Rep: ORF318 - Methanobacterium
           thermoformicicum
          Length = 160

 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 25/63 (39%), Positives = 38/63 (60%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + D   +P  I GL  LA GTS+PE V ++    +G   + I   +GSNTF+IL+ +G+P
Sbjct: 39  LADIAGIPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVP 98

Query: 400 WLV 402
            L+
Sbjct: 99  ALI 101



 Score = 37.1 bits (82), Expect = 0.88
 Identities = 27/112 (24%), Positives = 48/112 (42%)

Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
           I + I G   +A  +S PEL +          +L +G V+GS  FN+L      AL A  
Sbjct: 45  IPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVPALIAPV 104

Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKI 234
            +E          M+       L++   D K+     ++L+ +Y  Y++ ++
Sbjct: 105 PVEPLSLRFDAPIMILVTVLLVLLIKQGDMKLKRSGGIILLAVYISYVVMRL 156


>UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+
           antiporter, CaCA family - Halorubrum lacusprofundi ATCC
           49239
          Length = 326

 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 24/60 (40%), Positives = 37/60 (61%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           V D   G TI+AAGTS PE   S++  ++GH  M + N +GSN F++L  +G+   ++ L
Sbjct: 212 VSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVGNVVGSNVFNVLGIMGIAAFLRPL 271



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384
           WIG+ + + A +   V     V +   GLTI+A GTS PE V +V     G G +G+ N 
Sbjct: 21  WIGARALVDATVR--VARRFGVGELTIGLTIVAMGTSTPELVVTVDAALAGLGEIGVGNI 78

Query: 385 IGSNTFDILLCLGLPWLVK 403
           IGSN +++   LG   L++
Sbjct: 79  IGSNAYNLAFILGAVSLLR 97



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           L L  V   + V A   +     ++    G T +AA +S+PEL ++ V        + VG
Sbjct: 189 LALVLVSGHFMVEAASTLARSAGVSDWAIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVG 248

Query: 160 AVVGSAVFNVLAVPACCALF-----AGAVIELDWW 189
            VVGS VFNVL +    A        GA IE   W
Sbjct: 249 NVVGSNVFNVLGIMGIAAFLRPLAVGGAAIETVLW 283



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 2/119 (1%)

Query: 111 VPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
           V A   +  R  +     G T +A  +S+PEL +         G++GVG ++GS  +N+ 
Sbjct: 28  VDATVRVARRFGVGELTIGLTIVAMGTSTPELVVTVDAALAGLGEIGVGNIIGSNAYNLA 87

Query: 171 AVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
            +    +L    VI ++   V RD              L D  +   E  LL  ++  Y
Sbjct: 88  FILGAVSLL--RVIPVERSLVHRDGAALVLSTLVGAAALFDRTVTGVEGALLAGLFVAY 144


>UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1;
           Aquifex aeolicus|Rep: Putative uncharacterized protein -
           Aquifex aeolicus
          Length = 322

 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 26/65 (40%), Positives = 39/65 (60%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +P+ + GLT++A GTSLPE   +V    +    + + N IGSN  +ILL LG+  L+K L
Sbjct: 35  IPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGISLGNVIGSNIANILLILGVASLIKPL 94

Query: 406 FYPST 410
              +T
Sbjct: 95  TVHAT 99



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%)

Query: 311 RHSIYPLT-FIMCITWIGSVSYLVAWIIT-VVG--DTLNVPDSITGLTILAAGTSLPEAV 366
           + SI P   FI  I  +  +S    W +   VG    L V +++ GL ++A GTSLPE  
Sbjct: 166 KESISPFKGFIYFILGLTGLSLGADWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELF 225

Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408
           +S +   +G+  + + N  GSN F+  L LG   +++ +  P
Sbjct: 226 ASAVSAYKGNPDIALGNVAGSNIFNATLVLGTSSVIRDIPVP 267



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 20/69 (28%), Positives = 34/69 (49%)

Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163
           S+  D+ V     + + L ++  + G   +A  +S PELF + V  +    D+ +G V G
Sbjct: 186 SLGADWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAG 245

Query: 164 SAVFNVLAV 172
           S +FN   V
Sbjct: 246 SNIFNATLV 254



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L  FLL+     D  +     +  R  I   + G T +A  +S PE  +N        
Sbjct: 8   LTLGFFLLVKGA--DMLIEGAGGLARRFGIPEFVIGLTLVAFGTSLPEFTVNVSAALKDA 65

Query: 154 GDLGVGAVVGSAVFNVLAVPACCAL 178
             + +G V+GS + N+L +    +L
Sbjct: 66  SGISLGNVIGSNIANILLILGVASL 90


>UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=9; Bacteroidetes|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Flavobacteria
           bacterium BBFL7
          Length = 317

 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 30/112 (26%), Positives = 53/112 (47%)

Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALF 179
           +L ++  I G T ++ A+S+PEL ++          L +G V+GS + N+  V    AL 
Sbjct: 30  KLRLSRMIIGLTVVSFATSAPELIVSIQSALDGFSGLAIGNVIGSNIANIALVLGATALI 89

Query: 180 AGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
           A   I+ D++      MM       ++L   ++ + W   +LL  +  F IL
Sbjct: 90  APLAIDKDFFKFNWPWMMAFSILLYILLLSDNNLVRWEGGILLGSIIVFLIL 141



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 2/81 (2%)

Query: 325 WIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384
           W GS   LV   + +   +L +P+SI  ++++A GTS+PE  +S++   +    + + N 
Sbjct: 179 WQGS-ELLVKGAVDIAA-SLGIPESIIAVSMVALGTSVPELAASIIAALKKEKAISLGNL 236

Query: 385 IGSNTFDILLCLGLPWLVKSL 405
           IGSN F+I   LG+  L++ +
Sbjct: 237 IGSNIFNIGSVLGITALIQPI 257



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 23/62 (37%), Positives = 32/62 (51%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           L +   I GLT+++  TS PE + S+     G   + I N IGSN  +I L LG   L+ 
Sbjct: 31  LRLSRMIIGLTVVSFATSAPELIVSIQSALDGFSGLAIGNVIGSNIANIALVLGATALIA 90

Query: 404 SL 405
            L
Sbjct: 91  PL 92



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 8/143 (5%)

Query: 96  LYCFLLLGSVC----EDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV 151
           ++ FL LG +      +  V     I   L I   I   + +A  +S PEL  + +    
Sbjct: 167 IFMFLALGGLALWQGSELLVKGAVDIAASLGIPESIIAVSMVALGTSVPELAASIIAALK 226

Query: 152 TEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTL-L 210
            E  + +G ++GS +FN+ +V    AL     I+ +   +  + + +       +L L  
Sbjct: 227 KEKAISLGNLIGSNIFNIGSVLGITALIQPIQIQPEGMGLLNNDIFWMLGISFALLPLAF 286

Query: 211 DDKIYW---HEALLLVLMYTFYI 230
             K+Y    ++ +L +  Y  +I
Sbjct: 287 LPKVYHISRYKGILFLAAYLLFI 309


>UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=2; delta proteobacterium MLMS-1|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein - delta
           proteobacterium MLMS-1
          Length = 351

 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 38/67 (56%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           + + + + GLT+ A GTSLPE  +     +Q   T+ + N IGSN F++L+ LG+   + 
Sbjct: 239 MGISELVIGLTLAAIGTSLPELATCFAAIRQRQDTLLVGNIIGSNIFNLLMVLGITGTLL 298

Query: 404 SLFYPST 410
               P+T
Sbjct: 299 PFALPAT 305



 Score = 35.9 bits (79), Expect = 2.0
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYP 408
           + GLT++A GTSLPE   ++  + +G   + + N IGSN  +I    GL   +  LF+P
Sbjct: 79  LIGLTVVAFGTSLPELFIALGASWRGVPGIMLGNVIGSNIANI----GLILAISLLFFP 133


>UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 682

 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 3/139 (2%)

Query: 93  FLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           FL L CF L+G++  D+  P +  I + L ++  +AG TF+A  + +P++        + 
Sbjct: 97  FLIL-CFTLVGTIASDFLCPNLYTISKILRLSDRLAGLTFLALGNGAPDVLGTYKAMSMN 155

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
              L V  +VG+A F    V    A+     ++ D  S   D   +      + + ++  
Sbjct: 156 TESLAVSELVGAAFFATTIVVGLIAVIHPFEVKRD--SFIIDFGFFLLAAMVVFVAIVRS 213

Query: 213 KIYWHEALLLVLMYTFYIL 231
            +    +L L L+Y  Y+L
Sbjct: 214 TLSIWTSLSLCLIYLSYVL 232



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 304 TIPDCRHRHSIYP--LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTS 361
           TIP C+H   +      F+  I WI   +  +  I   +  + N+ D I GLT+ A G S
Sbjct: 510 TIPSCKHYIIMTGSLFGFVSSICWIALFATEIISIFQAIATSYNLSDDILGLTVFAWGNS 569

Query: 362 LPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + + +S+  + + G   M      G+    + L LG+
Sbjct: 570 VGDLISNFTIARMGLPLMAFGACFGAPLLSLCL-LGI 605


>UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30;
           Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6
           precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo
           sapiens (Human)
          Length = 584

 Score = 50.4 bits (115), Expect = 9e-05
 Identities = 27/87 (31%), Positives = 47/87 (54%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F+    WI + +  V  I+  +G    + +++ GLT+LA G S+ +A S   + +QG+
Sbjct: 424 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 483

Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403
             M  S   G   F+IL+ +GL  L++
Sbjct: 484 PRMAFSACFGGIIFNILVGVGLGCLLQ 510



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 3/148 (2%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           + L+    LY FL+LG     +F P +  I   L ++ ++AG TF+A  + +P++F   V
Sbjct: 100 VTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALV 159

Query: 148 G-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
             +      L +GA+ G+ V     V     +    +         RD + Y        
Sbjct: 160 AFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASR--PFFRDIVFYMVAVFLTF 217

Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKI 234
           L L   ++    AL  + +Y FY++  I
Sbjct: 218 LMLFRGRVTLAWALGYLGLYVFYVVTVI 245


>UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: Na/Ca,K-exchanger - Entamoeba
           histolytica HM-1:IMSS
          Length = 575

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 25/118 (21%), Positives = 59/118 (50%), Gaps = 2/118 (1%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
           +++ +V  WP+ +IL  TIPD + +    + P+T ++ + +IG  +++  +    + + +
Sbjct: 378 QRIVYVFNWPLLVILAYTIPDVKIKTCARMTPVTILISLLYIGVFAFVGVFCGYRLSEVI 437

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
             P  + G T +A   S+   +S  +  +     + I NS   + F   + + +PW++
Sbjct: 438 TCPPDVLGFTFVALFLSIRHIISGWVSGRMMCANLAILNSYSMSLFFTNVAIVIPWMI 495


>UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14779,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 880

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
           F + I+ IG ++ +   + +  G T+ + DS+T +  +A GTS+P+   S V   +  + 
Sbjct: 712 FFVSISLIGVLTAITGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYA 771

Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSL 405
              I N  GSN  ++ L +G+ W + ++
Sbjct: 772 DASIGNVTGSNAVNVFLGIGVAWTIAAV 799



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           ++  T MA  SS+PE+ ++ +   G     G LG   +VGSA FN+  + A C
Sbjct: 77  VSNLTLMALGSSAPEILLSVIEVCGHNFESGALGPSTIVGSAAFNMFVIIAIC 129


>UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
           n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+
           antiporter, CaCA family - Sulfurovum sp. (strain
           NBC37-1)
          Length = 310

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 24/58 (41%), Positives = 35/58 (60%)

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           N+P+ I G T++A GTSLPE  +S+  +      + ISN IGSN  +I L L   +L+
Sbjct: 32  NIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLASVFLI 89



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)

Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174
           E I  + NI   I GAT +A  +S PE+  +   +   + ++ +  V+GS + N+  V A
Sbjct: 25  EKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLA 84

Query: 175 CCALFAGAVI-ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
              L A  +  + D+++  +D           IL +LD  I   +A+LL+L+   Y+L
Sbjct: 85  SVFLIARNISPKRDFFA--KDSTWALVPVLVFILMILDGVISRFDAVLLLLLMGAYLL 140



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 18/58 (31%), Positives = 32/58 (55%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           +  +  + + + G+ +++ GTS+PE V S+    +G   M I N IGSN  +  + LG
Sbjct: 192 IAKSFGISEWVIGIVMISLGTSMPELVVSISAAMKGKVDMAIGNIIGSNLANTTVVLG 249


>UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella
           pneumophila|Rep: Na/Ca antiporter - Legionella
           pneumophila (strain Corby)
          Length = 319

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 23/51 (45%), Positives = 35/51 (68%)

Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           GLTI+A G+SLPE  +S++   +G  ++ I   IGSN +++LL L LP L+
Sbjct: 209 GLTIIAIGSSLPELTTSLVAAIKGEDSIAIGTIIGSNIYNLLLILALPGLL 259



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 24/81 (29%), Positives = 40/81 (49%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L++   LL+  +C  Y V     I +   I+    G T +A  SS PEL  + V     E
Sbjct: 174 LSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGE 233

Query: 154 GDLGVGAVVGSAVFNVLAVPA 174
             + +G ++GS ++N+L + A
Sbjct: 234 DSIAIGTIIGSNIYNLLLILA 254



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 23/52 (44%), Positives = 33/52 (63%)

Query: 352 GLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           GLTI+A GTS PE   S++ + +    + I N+IGSN  +I L LG+  L+K
Sbjct: 40  GLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANIGLILGIIILIK 91



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 16/50 (32%), Positives = 30/50 (60%)

Query: 120 RLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           R  ++  + G T +A  +S+PELFI+ + +   + DL +G  +GS + N+
Sbjct: 31  RFQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANI 80


>UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091;
           n=9; Methanococcales|Rep: Uncharacterized membrane
           protein MJ0091 - Methanococcus jannaschii
          Length = 302

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 25/123 (20%), Positives = 62/123 (50%), Gaps = 4/123 (3%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+FV   E I    N+++ + GAT MA  +S PE+  +   +++    + +G  +GS + 
Sbjct: 21  DWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCIC 80

Query: 168 NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYT 227
           N+  V    A+ +  +++    ++ ++ ++Y        +  +D    W + ++L++++ 
Sbjct: 81  NIGLVLGLSAIISPIIVDK---NLQKNILVYLLFVIFAAVIGIDG-FSWIDGVVLLILFI 136

Query: 228 FYI 230
            Y+
Sbjct: 137 IYL 139



 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 36/102 (35%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGD-----TLNVPDSITGLTILAAGTSLPEAVSSVLV 371
           + F + +  IG +  LV   + V G       L++ D + G T++A GTSLPE + S+  
Sbjct: 161 VVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAA 220

Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPEN 413
            K+  G M + N IGSN  DI    G    V SLF     EN
Sbjct: 221 AKRNLGGMVLGNVIGSNIADI----GGALAVGSLFMHLPAEN 258



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 24/78 (30%), Positives = 41/78 (52%)

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           NV + + G T++A GTSLPE ++S   +      + I N+IGS   +I L LGL  ++  
Sbjct: 35  NVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISP 94

Query: 405 LFYPSTPENHWVTDLYFI 422
           +      + + +  L F+
Sbjct: 95  IIVDKNLQKNILVYLLFV 112



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 94  LALYCFLLLGS-VCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           L L    L+G  V  + FV   + I   L+I+  + G T +A  +S PEL ++       
Sbjct: 165 LVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRN 224

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALF 179
            G + +G V+GS + ++    A  +LF
Sbjct: 225 LGGMVLGNVIGSNIADIGGALAVGSLF 251


>UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute
           carrier family 24 member 6; n=1; Apis mellifera|Rep:
           PREDICTED: similar to solute carrier family 24 member 6
           - Apis mellifera
          Length = 451

 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 2/105 (1%)

Query: 305 IPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPE 364
           IP   +  + +     M + ++  V+  V  ++  VG   ++ D++ G+T+LA G S+ +
Sbjct: 270 IPKFHNAFAFFGFFTAMMVVYL--VAKEVMAVLQCVGYAFSISDAMLGITLLAWGNSIGD 327

Query: 365 AVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409
            +++V + +QG   MG +   G   F+ LL LGL + V++   P+
Sbjct: 328 LIANVTIARQGFPRMGYAACFGGPMFNTLLGLGLTYGVEAAKDPN 372


>UniRef50_Q4SAM5 Cluster: Chromosome undetermined SCAF14681, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14681,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 473

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 25/57 (43%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVG 341
           K+L ++L  PI L LW T+PD R   S   +P+TF+  I WI   SYL+ W    VG
Sbjct: 135 KRLTYLLIVPIVLPLWLTLPDVRKPSSKKFFPITFLGAICWIAFFSYLMVWWAHQVG 191


>UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=1; Silicibacter sp. TM1040|Rep:
           K+-dependent Na+/Ca+ exchanger related-protein -
           Silicibacter sp. (strain TM1040)
          Length = 327

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 20/51 (39%), Positives = 34/51 (66%)

Query: 343 TLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDIL 393
           +  + +++ GLTI+A GTS+PE V+SV+   +  G +   N +GSN ++IL
Sbjct: 212 SFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNIL 262



 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 41/179 (22%), Positives = 70/179 (39%)

Query: 2   LIRTRQYERKHRVATIVRVVLFFGIPIVYMVAKSIASNQVIVFDEPEAFSSRHLLGIVEI 61
           +I  R   R+  V  ++  ++F G+  V+ + +   +  +I       F  R      + 
Sbjct: 94  IIVARAALRRDAVVMLLAALVFSGLAAVWPMGRLSGAALIIAMIGYITFVVRQERQNADT 153

Query: 62  ERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERL 121
                    L   + GL   Q + G  L    L     L+L  V     V     +    
Sbjct: 154 GALHDKGEALAGAAPGLDPAQTKSGRGLAVSLLLALGGLVLVVVGGAALVNGAVALARSF 213

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
            I+  + G T +A  +S PEL  + +     +GD+  G VVGS ++N+L +    AL A
Sbjct: 214 EISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNILGIGGTTALIA 272



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 23/59 (38%), Positives = 32/59 (54%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L V   + GLT++  GTS PE V+SV     G   +   N +GSN  +ILL  G+  L+
Sbjct: 33  LGVSPLVIGLTLVGFGTSTPELVTSVQAGLSGAPGIAYGNVVGSNIANILLIAGISALL 91



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 25/96 (26%), Positives = 39/96 (40%)

Query: 89  LLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVG 148
           +L   L L   L L  V  D  V        RL ++  + G T +   +S+PEL  +   
Sbjct: 1   MLEIGLLLVVGLALLMVGGDLLVRGAVQAAARLGVSPLVIGLTLVGFGTSTPELVTSVQA 60

Query: 149 TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
                  +  G VVGS + N+L +    AL    ++
Sbjct: 61  GLSGAPGIAYGNVVGSNIANILLIAGISALLCPIIV 96


>UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger
           related-protein; n=4; Chlorobium|Rep: K+-dependent
           Na+/Ca+ exchanger related-protein - Chlorobium
           ferrooxidans DSM 13031
          Length = 318

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 21/68 (30%), Positives = 39/68 (57%)

Query: 338 TVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
           T +     +   + G T++A GTS+PE  SS++   +GH  +G+   +GSN F+ LL +G
Sbjct: 188 TAIALAFGMDKFLIGATVVALGTSMPELASSLIAKYRGHDEVGLGTILGSNIFNGLLIVG 247

Query: 398 LPWLVKSL 405
           +  ++  +
Sbjct: 248 VTAMINPI 255



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 127 IAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIEL 186
           + GAT +A  +S PEL  + +  +    ++G+G ++GS +FN L +    A+     + L
Sbjct: 200 LIGATVVALGTSMPELASSLIAKYRGHDEVGLGTILGSNIFNGLLIVGVTAMINPIQVTL 259

Query: 187 DWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
                T   ++       L   L D +I   + + L+++Y  Y++
Sbjct: 260 ---RETGTALLIGITALLLTFPLSDGRIKKSQGVFLIMLYAGYLI 301



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 6/139 (4%)

Query: 97  YCFLLLG----SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVT 152
           Y +LL G    ++  D FV     I     IA  I GAT  A A+S+PEL +        
Sbjct: 4   YAYLLFGILFAALGGDLFVRGAVGIASSFRIAPGIIGATVAAFATSTPELSVAVNAGIAG 63

Query: 153 EGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
              + +G  +GS + N+  +       +G  I+    ++ RD  +         + LLD 
Sbjct: 64  SPQIAMGDALGSNIVNIAFILGIVLAISG--IDAPQDTIRRDYTVALLVPVITGILLLDG 121

Query: 213 KIYWHEALLLVLMYTFYIL 231
            +   +  L+V ++ F+ L
Sbjct: 122 LVSRLDGFLMVSIFLFWFL 140


>UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1;
           Thermococcus kodakarensis KOD1|Rep: Sodium/calcium
           antiporter - Pyrococcus kodakaraensis (Thermococcus
           kodakaraensis)
          Length = 311

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 22/66 (33%), Positives = 40/66 (60%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + + L V + + G TI+A GTSLPE  +++    +  G++ + N IG+N  + L+ LGL 
Sbjct: 192 IAEALGVAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLA 251

Query: 400 WLVKSL 405
            L++ +
Sbjct: 252 SLIRPI 257



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 20/62 (32%), Positives = 31/62 (50%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I E L +A  + GAT +A  +S PE+     G     G + VG ++G+ + N L V    
Sbjct: 192 IAEALGVAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLA 251

Query: 177 AL 178
           +L
Sbjct: 252 SL 253



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 19/69 (27%), Positives = 35/69 (50%)

Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
           I  V +   V   I  L +++  T+LPE  +S + +      + + N++GS   +I L L
Sbjct: 28  IVEVAEKAGVSPLIISLVVISLATTLPEITTSAMASITKAEGIALGNALGSIFANIALIL 87

Query: 397 GLPWLVKSL 405
           GL  +++ L
Sbjct: 88  GLASVIRPL 96


>UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5;
           Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
           - Dinoroseobacter shibae DFL 12
          Length = 321

 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 22/60 (36%), Positives = 39/60 (65%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           V D++ GL+++A GTSLPE  ++V+   +    + + N IGSN F+IL  LG+  +++ +
Sbjct: 205 VSDAVIGLSLVAIGTSLPELATAVVAAIKRQSDVVLGNVIGSNIFNILAILGITVVIQPM 264



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 19/59 (32%), Positives = 31/59 (52%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           + +   +   + GL I+  GTS PE + SV     G   + + N +GSN  +ILL +G+
Sbjct: 29  IAERFGISKLLIGLVIVGFGTSTPELLVSVNAALDGAPEIALGNVVGSNIANILLIIGI 87



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D  V     I     ++  + G + +A  +S PEL    V     + D+ +G V+GS +F
Sbjct: 190 DLLVQGSVSIARAYGVSDAVIGLSLVAIGTSLPELATAVVAAIKRQSDVVLGNVIGSNIF 249

Query: 168 NVLAV 172
           N+LA+
Sbjct: 250 NILAI 254



 Score = 34.3 bits (75), Expect = 6.2
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
           I ER  I+  + G   +   +S+PEL ++         ++ +G VVGS + N+L +
Sbjct: 29  IAERFGISKLLIGLVIVGFGTSTPELLVSVNAALDGAPEIALGNVVGSNIANILLI 84


>UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Sodium/calcium exchanger -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 329

 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 33/82 (40%), Positives = 42/82 (51%), Gaps = 8/82 (9%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL- 398
           V   L VPD   GLTILA GTSLPE  + +    +  G +   N +GSN F+IL   G+ 
Sbjct: 199 VARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVAGNILGSNVFNILGAGGIV 258

Query: 399 ----PWLVKSLFYPSTPENHWV 416
               P+ V  LF      +HWV
Sbjct: 259 ALFGPFEVAPLF---LQYDHWV 277



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 11/121 (9%)

Query: 115 EIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPA 174
           E +   L +  +  G T +A  +S PE+       F   GD+  G ++GS VFN+L    
Sbjct: 197 EGVARELGVPDEWIGLTILALGTSLPEIGAGLAAAFRQRGDVVAGNILGSNVFNILGAGG 256

Query: 175 CCALF-----AGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFY 229
             ALF     A   ++ D W +    +++        L +L  ++     +LL+L+Y  Y
Sbjct: 257 IVALFGPFEVAPLFLQYDHWVMGITAVLFAG------LVMLRVRMGRLLGVLLLLIYAAY 310

Query: 230 I 230
           I
Sbjct: 311 I 311



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 25/86 (29%), Positives = 44/86 (51%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           ++L+  LLL ++  D  V     +   + ++  +AG   +   +S+PE+FI+        
Sbjct: 8   ISLFGGLLLMALAGDLLVRGALGLGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGN 67

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALF 179
             L +G +VGS + N+L V A  ALF
Sbjct: 68  PGLAIGNIVGSNIANLLMVAAIPALF 93



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +G  + V   + G+ I+  GTS PE   S      G+  + I N +GSN  ++L+   +P
Sbjct: 31  LGRAMGVSPLVAGIFIVGFGTSAPEMFISANAALNGNPGLAIGNIVGSNIANLLMVAAIP 90

Query: 400 WLVKSLFYP 408
               +LF+P
Sbjct: 91  ----ALFFP 95


>UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane
           protein; n=3; Pyrococcus|Rep: Na+/Ca2+ exchange integral
           membrane protein - Pyrococcus abyssi
          Length = 314

 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 18/60 (30%), Positives = 39/60 (65%)

Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
           +P+ + G+T+++ GTSLPE  +S+    +G   + + N IG++  DIL+ +G+  +++ +
Sbjct: 196 IPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGIASIIRPI 255



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 313 SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVT 372
           +I    FI+ +  +   S +     T + +T  V + +  L + +  T+LPEA  S + +
Sbjct: 4   AIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISS 63

Query: 373 KQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            +G+  + + N++GS   +I L LG+  ++  L
Sbjct: 64  YKGNSGIALGNAVGSALANIALILGISAMITPL 96



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 6/143 (4%)

Query: 88  ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
           I+   F+     L+ GS   D FV A   I E   ++  +      + A++ PE  ++ +
Sbjct: 5   IVTAVFILGLILLIKGS---DIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAI 61

Query: 148 GTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLIL 207
            ++     + +G  VGSA+ N+  +    A+     +++D  +     +M        +L
Sbjct: 62  SSYKGNSGIALGNAVGSALANIALILGISAMI--TPLKVDEVANENSLIMLGVTLYAWLL 119

Query: 208 TLLDDKIYWHEALLLVLMYTFYI 230
            +++ +I   E L LVL+Y  ++
Sbjct: 120 -MINGEISRIEGLTLVLIYGAFL 141


>UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 318

 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           +     I+  + G + +A  +S PEL I+ V  F  E D+ VG V+GS ++N+LAV    
Sbjct: 197 LARNFGISELVVGLSVVAVGTSLPELAISTVAAFRKESDICVGNVLGSNIYNILAVLGIT 256

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY--WHEALLLVLMYTFYIL 231
           A+     ++++  S+  D  +       LI  ++   I   W E + L++ Y FY++
Sbjct: 257 AII--HPLQINTSSLQFDMPVMIVFSLLLIPMIMRKFILTRW-EGVFLLVGYIFYMI 310



 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FI   T IG    LV   I +  +   + + + GL+++A GTSLPE   S +   +    
Sbjct: 177 FIGLTTLIGGAHLLVNSAIYLARN-FGISELVVGLSVVAVGTSLPELAISTVAAFRKESD 235

Query: 379 MGISNSIGSNTFDILLCLGLPWLVKSL 405
           + + N +GSN ++IL  LG+  ++  L
Sbjct: 236 ICVGNVLGSNIYNILAVLGITAIIHPL 262



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 24/62 (38%), Positives = 36/62 (58%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
           LN+   I GLTI+A GTS PE V+ ++   +    + I N IGSN  ++ L LG+  ++ 
Sbjct: 34  LNIKPIIIGLTIIAFGTSAPELVTGIISGIRNLNDIAIGNVIGSNIANVGLVLGVTAIIL 93

Query: 404 SL 405
            L
Sbjct: 94  PL 95



 Score = 40.3 bits (90), Expect = 0.095
 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 121 LNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFA 180
           LNI   I G T +A  +S+PEL    +       D+ +G V+GS + NV  V    A+  
Sbjct: 34  LNIKPIIIGLTIIAFGTSAPELVTGIISGIRNLNDIAIGNVIGSNIANVGLVLGVTAIIL 93

Query: 181 GAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKI-YWHEALLLV--LMYTFYI 230
              +E++   + R+  +       L L   +  +  W   LL+V  ++YT YI
Sbjct: 94  PLKVEMN--LLRREIPIIIGISGLLYLMCRNGILSRWEGGLLVVGIVVYTCYI 144


>UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein,
           expressed; n=8; Oryza sativa|Rep: Sodium/calcium
           exchanger protein, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 597

 Score = 48.0 bits (109), Expect = 5e-04
 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 4/103 (3%)

Query: 306 PDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA 365
           P   H  +     F+M + W  +V+  +  ++      + V  +  GLT+LA G SL + 
Sbjct: 427 PPADHLAAWLAAGFVMSVAWAYAVATELLALLVSAAHVMGVDSAALGLTVLAWGNSLGDL 486

Query: 366 VSSVLVTKQGHGTMG----ISNSIGSNTFDILLCLGLPWLVKS 404
           V+++ V  +G G  G    ++   G   FD+L+ LG+  L+ S
Sbjct: 487 VANLAVASRGGGGGGAQVAVAGCYGGPVFDVLVGLGVSMLLSS 529



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 9/157 (5%)

Query: 82  QRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPE 141
           +R  G+ ++  +LA+  F LLG     YF  ++E +   L ++  IAG T ++  + +P+
Sbjct: 114 RRVLGYAVMAAWLAVL-FYLLGDTAAVYFCSSLEGLSRLLRLSPAIAGVTLLSLGNGAPD 172

Query: 142 LFINCVGTFVT---EGD---LGVGAVVGSAVFNVLAVPACCALFAGA-VIELDWWSVTRD 194
             ++ + +F +   EG+   +G+  V+GSA+    AV     +  GA  + +D     RD
Sbjct: 173 A-LSTIASFASGGGEGETTAVGLNGVLGSAMLVSSAVLGVIGVRLGARGVAVDRVDFYRD 231

Query: 195 CMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
                     + + L   ++    AL    +Y  Y++
Sbjct: 232 ASFLLAALAAVAVVLAAGEVTIWGALAFTSLYVVYVV 268


>UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           Na(+)/Ca(2+) antiporter - Uncultured methanogenic
           archaeon RC-I
          Length = 308

 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGD---TLNVPDSITGLTILAAGTSLPEAVSSVLVTK 373
           L  I  +  IG +     W++    D      +P S+ GLT++A GTS+PE V  +    
Sbjct: 5   LELIGLLVGIGLLVKGADWLVESARDLAFAAGIPASVIGLTLVAMGTSVPEFVVGIDSAL 64

Query: 374 QGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            G G + + N IG+N  ++ L +G+  +V  +
Sbjct: 65  SGVGQIAVGNVIGANISNLCLIIGVAAIVNRI 96



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 20/66 (30%), Positives = 37/66 (56%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           + +   V   +  +TI+A GTS+PE V++++ +++  G + + N IGS   + L  LG  
Sbjct: 190 LANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKDEGDLVMGNCIGSVIVNTLFILGAA 249

Query: 400 WLVKSL 405
            +V  L
Sbjct: 250 AIVSPL 255



 Score = 41.1 bits (92), Expect = 0.054
 Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 8/141 (5%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           + + C +L G V  D  V     +     ++  +   T +A  +S PE+    V +   E
Sbjct: 171 IGIACVILGGKVTVDSAVS----LANAFQVSPFLIAVTIIAIGTSMPEMVTALVASRKDE 226

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
           GDL +G  +GS + N L +    A+    V  L    V    ++       L + +   +
Sbjct: 227 GDLVMGNCIGSVIVNTLFILGAAAI----VSPLPIAGVIDILILLGIIVLLLPILVTRSQ 282

Query: 214 IYWHEALLLVLMYTFYILEKI 234
           I   E +LLV++Y  ++  K+
Sbjct: 283 IGHREGILLVVLYVIFVGYKV 303


>UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger
           antiporter; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Probable sodium/calcium exchanger antiporter -
           Psychroflexus torquis ATCC 700755
          Length = 158

 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 36/121 (29%), Positives = 56/121 (46%), Gaps = 13/121 (10%)

Query: 122 NIASDIAGATFMAAASSSPELFINCVGTFVTEGDL----GVGAVVGSAVFNVLAVPACCA 177
           N+   + GAT  A ASS PELFI     F  +  +    G+G   GS +FN L +P+   
Sbjct: 35  NLRDGVKGATINAVASSMPELFIALFFLFFLKDVVGFSGGLGTSFGSVLFNSLIIPSAAV 94

Query: 178 LFAGAVIELDWWSVT-------RDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
           L  G + + +  SV+       RD          LI  +   +I W E+ +L+ +Y  Y+
Sbjct: 95  L--GVLSKTNKKSVSVSRKIILRDGFWLLFVEFMLIYFIQQGEISWIESSVLITIYVLYV 152

Query: 231 L 231
           +
Sbjct: 153 M 153


>UniRef50_A0VUH2 Cluster: Sodium/calcium exchanger membrane region;
           n=10; Alphaproteobacteria|Rep: Sodium/calcium exchanger
           membrane region - Dinoroseobacter shibae DFL 12
          Length = 390

 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 23/77 (29%), Positives = 41/77 (53%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
           L F++ +  +GS  + +A +  V+     +  S+ G  + A  TS PE V+++   ++G 
Sbjct: 243 LQFVLLMLIMGSAGWCIAQLAQVLITRYELSSSMVGALMTAVVTSFPELVTTLAAVRRGA 302

Query: 377 GTMGISNSIGSNTFDIL 393
             + +   IG NTFDIL
Sbjct: 303 LQLAVGGIIGGNTFDIL 319


>UniRef50_A7THZ1 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 678

 Score = 47.2 bits (107), Expect = 8e-04
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 96  LYCFLLLGSVCEDYFVPAIEII-CERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG 154
           L CF+LLG V  DY +P++ II  +  NI+S I+G T ++  +S P++            
Sbjct: 40  LECFILLGLVTSDYLLPSLSIISTDVFNISSRISGITILSLGNSIPDITGTYQSMKKDAT 99

Query: 155 DLGVGAVVGSAVFNVLAVPACCAL 178
            L +G ++G  +F +  V    AL
Sbjct: 100 SLAIGELLGGLLFVLTVVIGLMAL 123



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 314 IYPLTFIMCITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLV 371
           + PL  + C   +G V+  YL+  +  +  D  N+   I+G+TIL+ G S+P+   +   
Sbjct: 34  VNPLFLLECFILLGLVTSDYLLPSLSIISTDVFNISSRISGITILSLGNSIPDITGTYQS 93

Query: 372 TKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
            K+   ++ I   +G   F + + +GL  L +++
Sbjct: 94  MKKDATSLAIGELLGGLLFVLTVVIGLMALSRTI 127



 Score = 41.5 bits (93), Expect = 0.041
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 4/116 (3%)

Query: 310 HRHSIYPLTFIMCITWIGSVSYLVAWIITVVG---DTLNVPDSITGLTILAAGTSLPEAV 366
           +R++   +  I  I  + ++SY V  ++ ++    +  N+   I GLTI A G S+ + +
Sbjct: 506 YRYNSNVVAIIEFIVSLCTISYSVKHVVRILTNWTERYNLTQEILGLTIFAWGNSVGDLI 565

Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL-FYPSTPENHWVTDLYF 421
           S+V  T+ G   + IS   G      L  LG+  L+  L  Y     + W T L F
Sbjct: 566 SNVTFTQLGAIDIAISACFGGPLLCFLFGLGIDGLLILLNNYGQEDSSIWKTSLVF 621


>UniRef50_Q4RST3 Cluster: Chromosome 12 SCAF14999, whole genome
            shotgun sequence; n=6; Deuterostomia|Rep: Chromosome 12
            SCAF14999, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1206

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 23/78 (29%), Positives = 44/78 (56%)

Query: 317  LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
            L F++    I + +  V  ++ ++G  L++ +++ GLT+LA G S+ +  S + + +QG+
Sbjct: 1025 LGFMVSAVLISAAASEVVSLLHMLGVVLSLSNTVLGLTLLAWGNSIGDCFSDITIARQGY 1084

Query: 377  GTMGISNSIGSNTFDILL 394
              M IS   G   F IL+
Sbjct: 1085 PRMAISACFGGIVFSILV 1102


>UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr6 scaffold_15, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 562

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 2/138 (1%)

Query: 96  LYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGD 155
           L  F LLG+   +YF  ++E +   L ++ +IAG T ++  + +P+LF + V     E +
Sbjct: 129 LVLFYLLGNTAANYFCCSLEGLSRILKLSPNIAGVTLLSLGNGAPDLFASIVSFMGDETE 188

Query: 156 -LGVGAVVGSAVF-NVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
            +G+ +++G A F + + V         +   ++  S   D   +      L++ ++  K
Sbjct: 189 KVGLNSILGGAFFVSSIVVGIISISVCHSRPSIERSSFIWDVTFFLLSLACLLVIIMLGK 248

Query: 214 IYWHEALLLVLMYTFYIL 231
           I    A+    +Y  Y+L
Sbjct: 249 INLWGAISFFSLYFIYVL 266



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG--- 375
           F+M ITW    +  +  ++  +G  L +  SI GLT+LA G SL + VS+V +   G   
Sbjct: 406 FLMSITWTYIAADELISLLVSLGLILGISPSILGLTVLAWGNSLGDLVSNVTMALNGGAE 465

Query: 376 HGTMGISNSIGSNTFDILLCLGLP 399
              + +S       F+ L+ LGLP
Sbjct: 466 GAQVALSGCYAGPIFNTLIGLGLP 489


>UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:
           ENSANGP00000016911 - Anopheles gambiae str. PEST
          Length = 563

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 42/127 (33%), Positives = 59/127 (46%), Gaps = 25/127 (19%)

Query: 74  PSDGLTRFQR-QHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIIC-------------- 118
           P D LT   R   G  L++ F  LY F+ + S+  D F+ AIE+I               
Sbjct: 58  PEDNLTTGDRIARG--LVYFFSLLYLFIGV-SIVSDRFMAAIEVITSKEKEVRVRKAGGE 114

Query: 119 ERLNIA----SDIAGATFMAAASSSPELF---INCVGTFVTEGDLGVGAVVGSAVFNVLA 171
           E++ +       +A  T MA  SS+PE+    I  V      GDLG G +VGSA +N+  
Sbjct: 115 EQIVVVRVWNETVANLTLMALGSSAPEILLSIIEIVAKNFNAGDLGPGTIVGSAAYNLFV 174

Query: 172 VPACCAL 178
           + A C L
Sbjct: 175 IMAICVL 181


>UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces
           cerevisiae YDL206w; n=1; Candida glabrata|Rep: Similar
           to tr|Q12424 Saccharomyces cerevisiae YDL206w - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 748

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 3/133 (2%)

Query: 275 VWSFPGDKIS--FWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYL 332
           V+SF  D +   +W  L  ++     LI  A + D + +H      F++ +  I    +L
Sbjct: 539 VFSFTLDNMFNIYWLSLVSIILLFSLLIFEAPLKDYQ-KHITSCFAFVLSLGGISFTVHL 597

Query: 333 VAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDI 392
           +  ++T   D+ N+  S+ GLTI A G S+ + VS++   + G   + +    GS    I
Sbjct: 598 ILDVLTSWADSFNLSPSVLGLTIFAWGNSIGDLVSNITFVQLGVIDVALGACFGSPLLYI 657

Query: 393 LLCLGLPWLVKSL 405
           L  +G+  ++  L
Sbjct: 658 LFGIGIDGILVML 670



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 3/92 (3%)

Query: 322 CITWIGSVS--YLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTM 379
           C   +G ++  YL+  +  +  D L + D ++G+T+LA G ++P+  ++    K+   ++
Sbjct: 45  CFMMLGILTSDYLIPSLSFISRDILKISDRVSGMTLLALGNAIPDITTTYQSMKRNETSL 104

Query: 380 GISNSIGSNTFDILLCLGLPWLVKSL-FYPST 410
            +   IG   F + + LG+  +V ++ F PST
Sbjct: 105 ALGELIGGVFFLLTVILGVVGIVSTVKFEPST 136



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%)

Query: 98  CFLLLGSVCEDYFVPAIEIIC-ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDL 156
           CF++LG +  DY +P++  I  + L I+  ++G T +A  ++ P++          E  L
Sbjct: 45  CFMMLGILTSDYLIPSLSFISRDILKISDRVSGMTLLALGNAIPDITTTYQSMKRNETSL 104

Query: 157 GVGAVVGSAVF 167
            +G ++G   F
Sbjct: 105 ALGELIGGVFF 115


>UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula
           marina DSM 3645|Rep: Cation antiporter - Blastopirellula
           marina DSM 3645
          Length = 382

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 4/72 (5%)

Query: 329 VSYLVAWIITVVGDTLNVPDSI----TGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNS 384
           V ++ A  +++V D + V   +     G T LA  TSLPE V++++  + G   M I N 
Sbjct: 178 VIFVAARYLSIVADRVAVVTGLGGTFVGSTFLALTTSLPELVTTIVAVRMGAADMAIGNI 237

Query: 385 IGSNTFDILLCL 396
           +GSN F+I + L
Sbjct: 238 LGSNAFNIAILL 249



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 24/62 (38%), Positives = 38/62 (61%), Gaps = 4/62 (6%)

Query: 113 AIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFV---TEG-DLGVGAVVGSAVFN 168
           A ++I E+  + S +AG   +AAA+S PE  IN     +   T G DL +G ++GS++FN
Sbjct: 4   AADVIGEKSGLGSSLAGLVLLAAATSLPEFAINVNAVQLPDYTNGVDLAMGNILGSSLFN 63

Query: 169 VL 170
           +L
Sbjct: 64  LL 65



 Score = 39.1 bits (87), Expect = 0.22
 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 114 IEIICERLNIASDIAG----ATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           + I+ +R+ + + + G    +TF+A  +S PEL    V   +   D+ +G ++GS  FN+
Sbjct: 186 LSIVADRVAVVTGLGGTFVGSTFLALTTSLPELVTTIVAVRMGAADMAIGNILGSNAFNI 245

Query: 170 -LAVPACCALFAGAVIE 185
            + +P       GA+++
Sbjct: 246 AILLPVDAFYTRGALLQ 262



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 6/94 (6%)

Query: 339 VVGDTLNVPDSITGLTILAAGTSLPE---AVSSVLVTKQGHGT-MGISNSIGSNTFDILL 394
           V+G+   +  S+ GL +LAA TSLPE    V++V +    +G  + + N +GS+ F++L+
Sbjct: 7   VIGEKSGLGSSLAGLVLLAAATSLPEFAINVNAVQLPDYTNGVDLAMGNILGSSLFNLLI 66

Query: 395 --CLGLPWLVKSLFYPSTPENHWVTDLYFIRINN 426
              + L +  K   + S    H ++ L  I + +
Sbjct: 67  LGIIDLAFRSKQRMFSSVSAAHALSALGSIALTS 100


>UniRef50_A1G1U8 Cluster: Sodium/calcium exchanger membrane region
           precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
           Sodium/calcium exchanger membrane region precursor -
           Stenotrophomonas maltophilia R551-3
          Length = 321

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 19/61 (31%), Positives = 40/61 (65%)

Query: 350 ITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPS 409
           + GL  +A GT+LPE  +++   ++GHG M +++ +GS+  ++LL +G   +++ L  P+
Sbjct: 207 LVGLLPVAIGTALPEVATAIAAARRGHGDMVMAHVLGSSVVNLLLVIGAMAVLQPLALPA 266

Query: 410 T 410
           +
Sbjct: 267 S 267



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           LLL ++  D  V A+  + +R   +   AG   +   +S PEL +N     V + +L +G
Sbjct: 13  LLLLALGGDSIVKAVSGLAQRFGASPFTAGLLLLGVTTSLPELAVNARALAVGQPELALG 72

Query: 160 AVVGSAVFNV---LAVPACCA--LFAGAVIELDWWSV 191
             VGS++ N+   LAV A  A  L    +  + WWS+
Sbjct: 73  NAVGSSIVNLGLTLAVAAMAAPLLLRARLQTVLWWSL 109


>UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
           n=3; Epsilonproteobacteria|Rep: Calcium:H+/Na+
           antiporter, CaCA family - Nitratiruptor sp. (strain
           SB155-2)
          Length = 308

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 25/66 (37%), Positives = 35/66 (53%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLP 399
           +  +L V + + GL ++A GTSLPE V S++        M I N IGSN  +  + LG  
Sbjct: 192 IARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMNDKADMSIGNIIGSNVANFSVVLGSA 251

Query: 400 WLVKSL 405
            LV  L
Sbjct: 252 ALVNPL 257



 Score = 44.4 bits (100), Expect = 0.006
 Identities = 22/64 (34%), Positives = 35/64 (54%)

Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
           ++ + + G T++A GTSLPE  +S+  +      + ISN IGS   +I L LG+ +L   
Sbjct: 32  DISEFVIGATLVALGTSLPEMAASIAASYNHKSDLAISNVIGSVIINITLVLGIVFLFSK 91

Query: 405 LFYP 408
              P
Sbjct: 92  KVTP 95



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 21/76 (27%), Positives = 38/76 (50%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ +   E I    +I+  + GAT +A  +S PE+  +   ++  + DL +  V+GS + 
Sbjct: 18  DFIIKESEKIALHFDISEFVIGATLVALGTSLPEMAASIAASYNHKSDLAISNVIGSVII 77

Query: 168 NVLAVPACCALFAGAV 183
           N+  V     LF+  V
Sbjct: 78  NITLVLGIVFLFSKKV 93



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 20/71 (28%), Positives = 34/71 (47%)

Query: 108 DYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVF 167
           D+ V +   I   L ++  + G   +A  +S PEL ++ V     + D+ +G ++GS V 
Sbjct: 183 DFAVESASHIARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMNDKADMSIGNIIGSNVA 242

Query: 168 NVLAVPACCAL 178
           N   V    AL
Sbjct: 243 NFSVVLGSAAL 253


>UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein
           B14D6.440; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein B14D6.440 - Neurospora crassa
          Length = 898

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 22/59 (37%), Positives = 34/59 (57%)

Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQG 375
           L F++ I WI +++  V  I+   G  L + ++I GLTI A G SL + V+ V V + G
Sbjct: 758 LGFVISIAWISTIANEVVGILKAFGVILGISEAILGLTIFAVGNSLGDLVADVTVARLG 816



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 154 GDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDK 213
           G + VG ++G+A F    V    AL     ++    +  RD + +       ++ LLD +
Sbjct: 6   GSMAVGELIGAAGFITAVVAGSMALVREFKVQKR--TFVRDIVYFIVSISFTMMFLLDQE 63

Query: 214 IYWHEALLLVLMYTFYIL 231
           ++  EA  +V  Y FY++
Sbjct: 64  LHLWEANAMVGCYIFYVI 81


>UniRef50_A1CY62 Cluster: Sodium/calcium transporter, putative; n=1;
           Neosartorya fischeri NRRL 181|Rep: Sodium/calcium
           transporter, putative - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 316

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 1/95 (1%)

Query: 305 IPDCRHRHSIYPLTFIMC-ITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363
           IP+      +Y +T ++  +  +    Y ++     + D+L++  ++ GLTI++  T+LP
Sbjct: 143 IPERSTTSLLYHVTQLLFGLIALSLAGYFLSHSAVSIADSLHLSGTVFGLTIVSFATTLP 202

Query: 364 EAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           E + +V+   +GH  +    + GSN F + LC G+
Sbjct: 203 EKLIAVVSGSRGHVNILAVTTAGSNIFLLTLCAGV 237


>UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane region;
           n=1; Syntrophomonas wolfei subsp. wolfei str.
           Goettingen|Rep: Sodium/calcium exchanger membrane region
           - Syntrophomonas wolfei subsp. wolfei (strain
           Goettingen)
          Length = 336

 Score = 45.6 bits (103), Expect = 0.003
 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 23/166 (13%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEG----D 155
           +LLG+   + FV  +E + E+LN++    G+   A  ++ PE  I  +    + G    D
Sbjct: 14  ILLGA---EVFVNGVEWLGEKLNLSEGAVGSVLAAVGTALPETLIPVIAIVFSHGKEGHD 70

Query: 156 LGVGAVVGS-AVFNVLA--VPACCALF------AGAVIELDWWSVTRDCMMYXXXXXXLI 206
           +G+GA++G+  + + LA  V     +F       G  ++ D+ S+TRD   +       I
Sbjct: 71  IGIGAILGAPLMLSTLAMFVTGLAVVFFSRRRIKGNKVQADYSSMTRDLSFFIIVFAAAI 130

Query: 207 LTLLDDKIYWHEALL----LVLMYTFYILEKIN---PLDASQRMTP 245
           +T        H  L+    +VL Y  Y+   I+    LD+S  + P
Sbjct: 131 ITGTMPPYLRHWQLIIAGFMVLSYFLYVYVMISEERDLDSSYELPP 176



 Score = 34.7 bits (76), Expect = 4.7
 Identities = 16/48 (33%), Positives = 25/48 (52%)

Query: 340 VGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGS 387
           +G+ LN+ +   G  + A GT+LPE +  V+     HG  G    IG+
Sbjct: 28  LGEKLNLSEGAVGSVLAAVGTALPETLIPVIAIVFSHGKEGHDIGIGA 75


>UniRef50_Q75D63 Cluster: ABR160Cp; n=1; Eremothecium gossypii|Rep:
           ABR160Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 650

 Score = 45.6 bits (103), Expect = 0.003
 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 10/171 (5%)

Query: 86  GFILLHCFLALYCFLLLGSVCEDYFVP-AIEIICERLNIASDIAGATFMAAASSSPELFI 144
           GF++L       CF+LLG    DY  P  + +  +R      I  A  +A  +SSP+LF 
Sbjct: 26  GFVVLTVLHLSVCFVLLGVSASDYLCPIVVTLTSQRNRPHKGILAAILLAWCNSSPDLFS 85

Query: 145 NCVGTFVTE--GDLGVGAVVGSAVFNVLAVP-ACCALFAGAVIEL---DWWSVTRDCMMY 198
           + +          L VG V+G+    +  V  A   +   A + L   +  S+  D +  
Sbjct: 86  SLMSWNAANNAAALSVGEVLGACGVIICVVQGAIFMVMRSAWVNLSAAERHSIIVDLLFA 145

Query: 199 XXXXXXLILTLLDDKIYWHEALLLVLMYTFYILEKINPLDASQRMTPRSVQ 249
                 +    L + +   + ++++L+Y  YI+ KI+   A QR  P +++
Sbjct: 146 MLAVCIIGYVCLMNAVSVLDCVVMLLIYAAYIVSKIS---AGQRHAPPTIE 193


>UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protein;
           n=3; Coxiella burnetii|Rep: Sodium/calcium antiporter
           family protein - Coxiella burnetii
          Length = 322

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 9/125 (7%)

Query: 56  LGIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIE 115
           + I  +++   P  + E P + L    ++    ++  FL L    +   +  D  V A +
Sbjct: 146 MSITSLKKKVAP--LQELPQEKLQMSAKKS---VIWWFLGLALLFISSELLVDGAVGAAQ 200

Query: 116 IICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPAC 175
           +    L I+  + G T +   +S PE     +G    E D+ +G ++GS +FN LAV A 
Sbjct: 201 L----LGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEHDIAIGHIIGSNIFNSLAVLAM 256

Query: 176 CALFA 180
            AL A
Sbjct: 257 PALIA 261



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 2/68 (2%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVL-VTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L + D + GLTI+   TSLPE  ++++ V K+ H  + I + IGSN F+ L  L +P L+
Sbjct: 202 LGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEH-DIAIGHIIGSNIFNSLAVLAMPALI 260

Query: 403 KSLFYPST 410
               +PS+
Sbjct: 261 APGRFPSS 268



 Score = 42.7 bits (96), Expect = 0.018
 Identities = 20/59 (33%), Positives = 32/59 (54%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLV 402
           L +P  + G+ ++  GTS PE + S +    G   + I N +GSN  +I L LG+  L+
Sbjct: 36  LKIPSLVIGIILVGFGTSFPELIVSAIAAFHGKTQISIGNVVGSNIANIGLILGVVALI 94



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 19/69 (27%), Positives = 33/69 (47%)

Query: 110 FVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
           F+ A   +   L I S + G   +   +S PEL ++ +  F  +  + +G VVGS + N+
Sbjct: 25  FITASAALARHLKIPSLVIGIILVGFGTSFPELIVSAIAAFHGKTQISIGNVVGSNIANI 84

Query: 170 LAVPACCAL 178
             +    AL
Sbjct: 85  GLILGVVAL 93


>UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein;
           n=1; Pisum sativum|Rep: Putative senescence-associated
           protein - Pisum sativum (Garden pea)
          Length = 284

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 6/122 (4%)

Query: 59  VEIERNCTPAAILEFPSDGLTRFQ--RQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEI 116
           +++   CT    +++      + Q  R  G+++L  +LA   F LLG+   DYF P++E 
Sbjct: 112 LKVNPQCTSEGYIDYLRFFFCKCQSFRVLGYLVLGVWLAAL-FYLLGNTAADYFCPSLEH 170

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           + E L +   +AG   +   + +P++F + + +FV  G   V  V+       L    CC
Sbjct: 171 LSELLKLPPTVAGVVLLPLGNGAPDVFAS-IASFV--GTDTVKLVLTCIAVPCLLQCCCC 227

Query: 177 AL 178
            +
Sbjct: 228 VV 229


>UniRef50_Q2GS93 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 401

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 36/148 (24%), Positives = 62/148 (41%), Gaps = 2/148 (1%)

Query: 94  LALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
           L L    L+ SVC DY V +I+ +    NI+    G   +    ++ E    CV     +
Sbjct: 250 LVLVVVTLIISVCADYMVDSIDALVATGNISKTFIGLILIPIVGNATEHVTACVVAVKDK 309

Query: 154 GDLGVGAVVGSAV-FNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDD 212
            DL +G  +GS++   +L  PA   L      ++     T + + +      +  T+ D 
Sbjct: 310 MDLAMGVAIGSSIQIALLVTPALVMLGWAIGQDMTLHFETFETIAFALSVLVVTYTVQDG 369

Query: 213 KIYWHEALLLVLMYTFYILE-KINPLDA 239
           K  + E  +L+ +Y    L    +P DA
Sbjct: 370 KSNYLEGAMLLGLYMIIALAFWASPADA 397


>UniRef50_Q9HS69 Cluster: Cation antiporter; n=2;
           Halobacteriaceae|Rep: Cation antiporter - Halobacterium
           salinarium (Halobacterium halobium)
          Length = 318

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 19/51 (37%), Positives = 31/51 (60%)

Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           D   GLT++A GTS+PE  +SV+   +      I N +GSN +++L  +G+
Sbjct: 209 DLFIGLTVIAFGTSVPELATSVVSALRDEADFSIGNVVGSNIYNVLAVIGI 259



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 24/79 (30%), Positives = 39/79 (49%)

Query: 100 LLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVG 159
           +LL  V  +  V A   +     I +   G T +A A+++PELF++ VG       + +G
Sbjct: 16  ILLLYVGAELLVSAASALALSHGIKAATVGVTVVAFATTAPELFVSTVGGITAGDSIALG 75

Query: 160 AVVGSAVFNVLAVPACCAL 178
            +VGS + N+  V    AL
Sbjct: 76  NIVGSNIANIGLVLGTAAL 94



 Score = 40.7 bits (91), Expect = 0.072
 Identities = 21/50 (42%), Positives = 28/50 (56%)

Query: 129 GATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCAL 178
           G T +A  +S PEL  + V     E D  +G VVGS ++NVLAV    A+
Sbjct: 213 GLTVIAFGTSVPELATSVVSALRDEADFSIGNVVGSNIYNVLAVIGIVAI 262


>UniRef50_Q31GA5 Cluster: Ca2+:cation antiporter (CaCA) family
           transporter precursor; n=1; Thiomicrospira crunogena
           XCL-2|Rep: Ca2+:cation antiporter (CaCA) family
           transporter precursor - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 339

 Score = 44.8 bits (101), Expect = 0.004
 Identities = 21/76 (27%), Positives = 40/76 (52%)

Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGT 378
           FI+     G   +++     V+ D   + D++ G  + A  TS PE V+++   + G  T
Sbjct: 192 FIILAVVTGIAGWVLMEAAKVISDQTGLSDTLVGGLLTALATSTPELVTTIAAIRYGALT 251

Query: 379 MGISNSIGSNTFDILL 394
           + +SN  G+N F++L+
Sbjct: 252 LAVSNIFGTNCFNMLV 267


>UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3;
           Borrelia burgdorferi group|Rep: Na+/Ca+ exchange
           protein, putative - Borrelia burgdorferi (Lyme disease
           spirochete)
          Length = 337

 Score = 44.4 bits (100), Expect = 0.006
 Identities = 22/55 (40%), Positives = 34/55 (61%)

Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
           L VP  + G+TI++  TS PE  +S++   +G   + +SN IGSN  ++LL L L
Sbjct: 44  LKVPTLLIGVTIVSFSTSAPELFTSLVAAFKGKNEIVVSNVIGSNIINMLLALPL 98



 Score = 43.6 bits (98), Expect = 0.010
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%)

Query: 321 MCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMG 380
           M   ++GS   LV   + +  +  NV + + G+ ++A GTS+PE V S+    +    + 
Sbjct: 201 MYFLYLGS-KLLVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSLFAIIRKESDIA 259

Query: 381 ISNSIGSNTFDI 392
             N IGSN F+I
Sbjct: 260 FGNIIGSNIFNI 271



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 7/150 (4%)

Query: 87  FILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINC 146
           F LL   +++Y FL LGS        A+ I     N++  + G   +A  +S PEL ++ 
Sbjct: 192 FNLLSFAISMY-FLYLGSKL--LVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSL 248

Query: 147 VGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
                 E D+  G ++GS +FN+  + A  + F   +++ D + +    M++      L+
Sbjct: 249 FAIIRKESDIAFGNIIGSNIFNIGFILASSSFFRPILLQ-DIYILDFSIMVFITLVLFLV 307

Query: 207 LTLLDDKIYWHE-ALLLVLMYTFYILEKIN 235
           +      ++    +L+ +L+Y  Y L   N
Sbjct: 308 VKF--KGVFGRGISLIFLLLYFLYNLMLFN 335



 Score = 38.3 bits (85), Expect = 0.38
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 117 ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
           I   L + + + G T ++ ++S+PELF + V  F  + ++ V  V+GS + N+L      
Sbjct: 40  IATYLKVPTLLIGVTIVSFSTSAPELFTSLVAAFKGKNEIVVSNVIGSNIINMLLALPLA 99

Query: 177 ALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIY 215
             F    I+ D+  +    M        L+L   D + Y
Sbjct: 100 GFF--LKIKADFKRLKLSFMFLFLLMFLLLLLSFDFRSY 136


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.327    0.141    0.449 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 470,374,848
Number of Sequences: 1657284
Number of extensions: 19064628
Number of successful extensions: 54884
Number of sequences better than 10.0: 316
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 53734
Number of HSP's gapped (non-prelim): 1043
length of query: 427
length of database: 575,637,011
effective HSP length: 103
effective length of query: 324
effective length of database: 404,936,759
effective search space: 131199509916
effective search space used: 131199509916
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 74 (33.9 bits)

- SilkBase 1999-2023 -