Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000688-TA|BGIBMGA000688-PA|IPR004481|K+-dependent
Na+/Ca+ exchanger related-protein, IPR004837|Sodium/calcium exchanger
membrane region
(427 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 2... 268 2e-71
BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 2... 268 2e-71
AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX pro... 268 2e-71
BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 2... 212 2e-54
AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca excha... 212 2e-54
AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca excha... 212 2e-54
AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca excha... 209 1e-53
AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 2... 194 4e-49
AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 2... 194 4e-49
AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 2... 194 4e-49
AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 2... 194 4e-49
AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 2... 194 4e-49
AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 2... 194 4e-49
AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/... 194 4e-49
BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein. 166 2e-40
AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 166 2e-40
AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 166 2e-40
AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein. 166 2e-40
AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+... 165 2e-40
BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 2... 158 3e-38
AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 2... 158 3e-38
AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 2... 158 3e-38
AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 2... 158 3e-38
AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 2... 158 3e-38
AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 2... 158 3e-38
AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 2... 158 3e-38
AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium pot... 158 3e-38
AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium pot... 158 3e-38
BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein. 143 1e-33
AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein pr... 130 9e-30
AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens ... 91 9e-18
M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein. 58 8e-08
BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein. 58 8e-08
BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein. 58 8e-08
AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchange... 58 8e-08
AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchange... 58 8e-08
AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchange... 58 8e-08
AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8... 58 8e-08
AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3 pr... 56 3e-07
AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3 pr... 56 3e-07
AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isof... 56 3e-07
AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchange... 56 3e-07
AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchange... 56 3e-07
AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 56 3e-07
AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isof... 56 3e-07
AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 56 3e-07
AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein. 52 3e-06
BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein. 50 1e-05
AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent... 50 1e-05
AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent... 50 1e-05
AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein. 44 0.001
AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isof... 40 0.022
BC114217-1|AAI14218.1| 210|Homo sapiens SLC8A3 protein protein. 35 0.48
AC007377-1|AAX81985.1| 245|Homo sapiens unknown protein. 33 1.5
AL513323-4|CAI15595.1| 329|Homo sapiens olfactory receptor, fam... 32 3.4
AL512764-1|CAC21681.1| 793|Homo sapiens hypothetical protein pr... 32 3.4
AC007254-1|AAF19235.1| 124|Homo sapiens unknown protein. 32 4.5
BC130437-1|AAI30438.1| 504|Homo sapiens DMRT-like family A1 pro... 31 7.8
BC130435-1|AAI30436.1| 504|Homo sapiens DMRT-like family A1 pro... 31 7.8
AY424283-1|AAR08371.1| 330|Homo sapiens progestin and adipoQ re... 31 7.8
AL161730-1|CAH73857.1| 504|Homo sapiens DMRT-like family A1 pro... 31 7.8
AK096011-1|BAC04672.1| 504|Homo sapiens protein ( Homo sapiens ... 31 7.8
AK000197-1|BAA91004.1| 330|Homo sapiens protein ( Homo sapiens ... 31 7.8
AJ290954-1|CAC16590.1| 263|Homo sapiens putative DMO orthologue... 31 7.8
>BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 268 bits (658), Expect = 2e-71
Identities = 139/380 (36%), Positives = 219/380 (57%), Gaps = 39/380 (10%)
Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
C + EFP TR +R+ G I+++ + +Y F+ + VC++YF+P++EII E L ++
Sbjct: 46 CVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLS 105
Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
D+AG TFMAA SS+PEL +G F+T+GD+G+ ++GSA++N+L + A C L + V
Sbjct: 106 QDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVS 165
Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTF-------------YIL 231
L W + RDC Y ++ + D+++YW+E LL+L+Y YI+
Sbjct: 166 TLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYII 225
Query: 232 EKINPLDAS-QRMTPRSVQN---GDLERGIEMTRRHDSTGSDI---------------ST 272
+K +P A + RS Q G + G RR T S I
Sbjct: 226 KKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSISLHGL 285
Query: 273 SSVWSFPGDKISF----WKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWI 326
S V P + K++FWVL+ PI +L+ T PDCR + + + +TF M WI
Sbjct: 286 SQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWI 345
Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
+ +Y++ W++T+ G+TL +PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +G
Sbjct: 346 SAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVG 405
Query: 387 SNTFDILLCLGLPWLVKSLF 406
SN FD +LCLG+PW +K+ F
Sbjct: 406 SNVFD-MLCLGIPWFIKTAF 424
>BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 268 bits (658), Expect = 2e-71
Identities = 139/380 (36%), Positives = 219/380 (57%), Gaps = 39/380 (10%)
Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
C + EFP TR +R+ G I+++ + +Y F+ + VC++YF+P++EII E L ++
Sbjct: 46 CVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLS 105
Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
D+AG TFMAA SS+PEL +G F+T+GD+G+ ++GSA++N+L + A C L + V
Sbjct: 106 QDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVS 165
Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTF-------------YIL 231
L W + RDC Y ++ + D+++YW+E LL+L+Y YI+
Sbjct: 166 TLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYII 225
Query: 232 EKINPLDAS-QRMTPRSVQN---GDLERGIEMTRRHDSTGSDI---------------ST 272
+K +P A + RS Q G + G RR T S I
Sbjct: 226 KKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSISLHGL 285
Query: 273 SSVWSFPGDKISF----WKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWI 326
S V P + K++FWVL+ PI +L+ T PDCR + + + +TF M WI
Sbjct: 286 SQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWI 345
Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
+ +Y++ W++T+ G+TL +PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +G
Sbjct: 346 SAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVG 405
Query: 387 SNTFDILLCLGLPWLVKSLF 406
SN FD +LCLG+PW +K+ F
Sbjct: 406 SNVFD-MLCLGIPWFIKTAF 424
>AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX
protein.
Length = 500
Score = 268 bits (658), Expect = 2e-71
Identities = 139/380 (36%), Positives = 219/380 (57%), Gaps = 39/380 (10%)
Query: 65 CTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIA 124
C + EFP TR +R+ G I+++ + +Y F+ + VC++YF+P++EII E L ++
Sbjct: 46 CVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLS 105
Query: 125 SDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVI 184
D+AG TFMAA SS+PEL +G F+T+GD+G+ ++GSA++N+L + A C L + V
Sbjct: 106 QDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVS 165
Query: 185 ELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTF-------------YIL 231
L W + RDC Y ++ + D+++YW+E LL+L+Y YI+
Sbjct: 166 TLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYII 225
Query: 232 EKINPLDAS-QRMTPRSVQN---GDLERGIEMTRRHDSTGSDI---------------ST 272
+K +P A + RS Q G + G RR T S I
Sbjct: 226 KKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSISLHGL 285
Query: 273 SSVWSFPGDKISF----WKKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWI 326
S V P + K++FWVL+ PI +L+ T PDCR + + + +TF M WI
Sbjct: 286 SQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWI 345
Query: 327 GSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIG 386
+ +Y++ W++T+ G+TL +PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +G
Sbjct: 346 SAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVG 405
Query: 387 SNTFDILLCLGLPWLVKSLF 406
SN FD +LCLG+PW +K+ F
Sbjct: 406 SNVFD-MLCLGIPWFIKTAF 424
>BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 4 protein.
Length = 605
Score = 212 bits (517), Expect = 2e-54
Identities = 100/211 (47%), Positives = 142/211 (67%), Gaps = 5/211 (2%)
Query: 47 PEAFSSRHLLGIV---EIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLG 103
P+ + +R L+ V + +NCT AI EFP+D + +RQHG +LLH ALY F L
Sbjct: 39 PDTWRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALA 98
Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163
VC+D+FVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VG
Sbjct: 99 IVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVG 158
Query: 164 SAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223
SAVFN+L + C LFAG V+ L WW+V RD + Y LI+ + D++I W E L+L+
Sbjct: 159 SAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLI 218
Query: 224 LMYTFYIL-EKIN-PLDASQRMTPRSVQNGD 252
++Y FYIL K N + A + +S+ NG+
Sbjct: 219 ILYVFYILIMKYNVKMQAFFTVKQKSIANGN 249
Score = 130 bits (314), Expect = 9e-30
Identities = 55/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
K+ WV TWP+ +L TIP+C + +TFI WI SY++ W++T++G TL
Sbjct: 407 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 466
Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
+PD I G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 467 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 526
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/57 (35%), Positives = 35/57 (61%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ HG +G+ +GS F+IL +G+
Sbjct: 114 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 458 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 514
>AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 586
Score = 212 bits (517), Expect = 2e-54
Identities = 100/211 (47%), Positives = 142/211 (67%), Gaps = 5/211 (2%)
Query: 47 PEAFSSRHLLGIV---EIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLG 103
P+ + +R L+ V + +NCT AI EFP+D + +RQHG +LLH ALY F L
Sbjct: 39 PDTWRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALA 98
Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163
VC+D+FVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VG
Sbjct: 99 IVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVG 158
Query: 164 SAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223
SAVFN+L + C LFAG V+ L WW+V RD + Y LI+ + D++I W E L+L+
Sbjct: 159 SAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLI 218
Query: 224 LMYTFYIL-EKIN-PLDASQRMTPRSVQNGD 252
++Y FYIL K N + A + +S+ NG+
Sbjct: 219 ILYVFYILIMKYNVKMQAFFTVKQKSIANGN 249
Score = 130 bits (314), Expect = 9e-30
Identities = 55/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
K+ WV TWP+ +L TIP+C + +TFI WI SY++ W++T++G TL
Sbjct: 388 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 447
Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
+PD I G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 448 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 507
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/57 (35%), Positives = 35/57 (61%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ HG +G+ +GS F+IL +G+
Sbjct: 114 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 439 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 495
>AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 605
Score = 212 bits (517), Expect = 2e-54
Identities = 100/211 (47%), Positives = 142/211 (67%), Gaps = 5/211 (2%)
Query: 47 PEAFSSRHLLGIV---EIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLG 103
P+ + +R L+ V + +NCT AI EFP+D + +RQHG +LLH ALY F L
Sbjct: 39 PDTWRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALA 98
Query: 104 SVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVG 163
VC+D+FVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VG
Sbjct: 99 IVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVG 158
Query: 164 SAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLV 223
SAVFN+L + C LFAG V+ L WW+V RD + Y LI+ + D++I W E L+L+
Sbjct: 159 SAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLI 218
Query: 224 LMYTFYIL-EKIN-PLDASQRMTPRSVQNGD 252
++Y FYIL K N + A + +S+ NG+
Sbjct: 219 ILYVFYILIMKYNVKMQAFFTVKQKSIANGN 249
Score = 130 bits (314), Expect = 9e-30
Identities = 55/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
K+ WV TWP+ +L TIP+C + +TFI WI SY++ W++T++G TL
Sbjct: 407 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 466
Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
+PD I G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 467 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 526
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/57 (35%), Positives = 35/57 (61%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ HG +G+ +GS F+IL +G+
Sbjct: 114 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 458 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 514
>AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 558
Score = 209 bits (511), Expect = 1e-53
Identities = 96/192 (50%), Positives = 133/192 (69%), Gaps = 2/192 (1%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT AI EFP+D + +RQHG +LLH ALY F L VC+D+FVP++E ICERL+
Sbjct: 11 KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLH 70
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 71 LSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 130
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL-EKIN-PLDAS 240
V+ L WW+V RD + Y LI+ + D++I W E L+L+++Y FYIL K N + A
Sbjct: 131 VVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 190
Query: 241 QRMTPRSVQNGD 252
+ +S+ NG+
Sbjct: 191 FTVKQKSIANGN 202
Score = 130 bits (314), Expect = 9e-30
Identities = 55/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
K+ WV TWP+ +L TIP+C + +TFI WI SY++ W++T++G TL
Sbjct: 360 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 419
Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
+PD I G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 420 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 479
Score = 46.4 bits (105), Expect = 2e-04
Identities = 20/57 (35%), Positives = 35/57 (61%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ HG +G+ +GS F+IL +G+
Sbjct: 67 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 123
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 411 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 467
>AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 144
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 204
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 205 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 253
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 509
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 510 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 566
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 141 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 554
>AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/Ca
exchanger NCKX3 protein.
Length = 625
Score = 194 bits (474), Expect = 4e-49
Identities = 85/169 (50%), Positives = 119/169 (70%)
Query: 63 RNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLN 122
+NCT A+ EFP+D T R+ G ++LH A+Y F L VC+D+FVP++E ICERL+
Sbjct: 66 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLH 125
Query: 123 IASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGA 182
++ D+AGATFMAA SS+PELF + +G F+T+GD+GVG +VGSAVFN+L + C LFAG
Sbjct: 126 LSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ 185
Query: 183 VIELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
V+ L W + RD + Y LI+ + D+K+ W E+L+LVLMY YI+
Sbjct: 186 VVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIV 234
Score = 132 bits (318), Expect = 3e-30
Identities = 54/117 (46%), Positives = 82/117 (70%), Gaps = 2/117 (1%)
Query: 291 WVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPD 348
W TWP+ +L+ T+P+C + +TF WI + SY++ W++T++G TL +PD
Sbjct: 431 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPD 490
Query: 349 SITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
I G+T LAAGTS+P+ ++S++V +QG G M +SNSIGSN FDIL+ LGLPW +++L
Sbjct: 491 VIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTL 547
Score = 42.7 bits (96), Expect = 0.002
Identities = 19/57 (33%), Positives = 34/57 (59%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGL 398
+ L++ + + G T +AAG+S PE +SV+ G +G+ +GS F+IL +G+
Sbjct: 122 ERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 178
Score = 36.7 bits (81), Expect = 0.16
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 479 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDIL 535
>BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein.
Length = 1069
Score = 166 bits (403), Expect = 2e-40
Identities = 72/159 (45%), Positives = 107/159 (67%)
Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498
Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW +
Sbjct: 499 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
RD Y LIL LD I W E+LLL+L Y FY+
Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597
Score = 81.8 bits (193), Expect = 4e-15
Identities = 42/100 (42%), Positives = 67/100 (67%), Gaps = 4/100 (4%)
Query: 306 PDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA 365
P+ R + +IY F++ I + + V + VG+T+ + + I GLTILAAGTS+P+
Sbjct: 902 PETRQKQAIY--LFLLPIVF--PLWLTVPDVRRQVGETIGISEEIMGLTILAAGTSIPDL 957
Query: 366 VSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
++SV+V ++G G M +S+S+GSN FDI + L +PWL+ SL
Sbjct: 958 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSL 997
Score = 47.2 bits (107), Expect = 1e-04
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G
Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 39.1 bits (87), Expect = 0.029
Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 95 ALYCFLLLGSVCEDYFVPAIEI-ICERLNIASDIAGATFMAAASSSPELFINCVGTFVTE 153
A+Y FLL VP + + E + I+ +I G T +AA +S P+L + +
Sbjct: 909 AIYLFLLPIVFPLWLTVPDVRRQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGL 968
Query: 154 GDLGVGAVVGSAVFNV-LAVPACCALFA 180
GD+ V + VGS +F++ + +P LF+
Sbjct: 969 GDMAVSSSVGSNIFDITVGLPVPWLLFS 996
>AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger protein.
Length = 1099
Score = 166 bits (403), Expect = 2e-40
Identities = 72/159 (45%), Positives = 107/159 (67%)
Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498
Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW +
Sbjct: 499 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
RD Y LIL LD I W E+LLL+L Y FY+
Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597
Score = 115 bits (276), Expect = 4e-25
Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
K+ ++ PI LW T+PD R + S + TF+ I WI SYL+ W VG+T+
Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETI 966
Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
+ + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 967 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1026
Query: 405 L 405
L
Sbjct: 1027 L 1027
Score = 47.2 bits (107), Expect = 1e-04
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G
Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 38.7 bits (86), Expect = 0.039
Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P
Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023
Query: 178 LFA 180
LF+
Sbjct: 1024 LFS 1026
>AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger splice variant protein.
Length = 1099
Score = 166 bits (403), Expect = 2e-40
Identities = 72/159 (45%), Positives = 107/159 (67%)
Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498
Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW +
Sbjct: 499 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
RD Y LIL LD I W E+LLL+L Y FY+
Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597
Score = 115 bits (276), Expect = 4e-25
Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
K+ ++ PI LW T+PD R + S + TF+ I WI SYL+ W VG+T+
Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETI 966
Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
+ + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 967 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1026
Query: 405 L 405
L
Sbjct: 1027 L 1027
Score = 47.2 bits (107), Expect = 1e-04
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G
Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 38.7 bits (86), Expect = 0.039
Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P
Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023
Query: 178 LFA 180
LF+
Sbjct: 1024 LFS 1026
>AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein.
Length = 988
Score = 166 bits (403), Expect = 2e-40
Identities = 72/159 (45%), Positives = 107/159 (67%)
Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 442 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 501
Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW +
Sbjct: 502 FMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 561
Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
RD Y LIL LD I W E+LLL+L Y FY+
Sbjct: 562 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 600
Score = 47.2 bits (107), Expect = 1e-04
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G
Sbjct: 486 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 544
Score = 41.9 bits (94), Expect = 0.004
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAW 335
K+ ++ PI LW T+PD R + S + TF+ I WI SYL+ W
Sbjct: 892 KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVW 942
>AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+
exchanger protein.
Length = 1081
Score = 165 bits (402), Expect = 2e-40
Identities = 72/159 (45%), Positives = 107/159 (67%)
Query: 72 EFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGAT 131
E+P D + +R+ G+++LH F +Y F+ L VC++YFVPA+ +I ++L I+ D+AGAT
Sbjct: 439 EYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGAT 498
Query: 132 FMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSV 191
FMAA S+PELF + +G F++ ++G+G +VGSAVFN+L V C+LF+ ++ L WW +
Sbjct: 499 FMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Query: 192 TRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYI 230
RD Y LIL LD I W E+LLL+L Y FY+
Sbjct: 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYV 597
Score = 115 bits (276), Expect = 4e-25
Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 2/121 (1%)
Query: 287 KKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
K+ ++ PI LW T+PD R + S + TF+ I WI SYL+ W VG+T+
Sbjct: 889 KQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETI 948
Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
+ + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L +PWL+ S
Sbjct: 949 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFS 1008
Query: 405 L 405
L
Sbjct: 1009 L 1009
Score = 46.8 bits (106), Expect = 1e-04
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 339 VVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLG 397
V+ D L + + + G T +AAG S PE +S++ H +GI +GS F+IL +G
Sbjct: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 38.7 bits (86), Expect = 0.039
Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV-LAVPACCA 177
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++ + +P
Sbjct: 946 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1005
Query: 178 LFA 180
LF+
Sbjct: 1006 LFS 1008
>BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 588 TVIHRFQP 595
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 395 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 451
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 452 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 510
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 511 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 570
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 571 TVIHRFQP 578
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 559
>AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 588 TVIHRFQP 595
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 588 TVIHRFQP 595
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 395 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 451
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 452 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 510
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 511 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 570
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 571 TVIHRFQP 578
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 559
>AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 588 TVIHRFQP 595
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 395 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 451
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 452 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 510
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 511 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 570
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 571 TVIHRFQP 578
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 559
>AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium
potassium exchanger splice variant protein.
Length = 644
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 395 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 451
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 452 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 510
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 511 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 570
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 571 TVIHRFQP 578
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 559
>AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium
potassium exchanger protein.
Length = 661
Score = 158 bits (384), Expect = 3e-38
Identities = 71/168 (42%), Positives = 107/168 (63%)
Query: 64 NCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNI 123
N T A ++P D + +R+ G I+LH +Y F+ L VC+++FVP++ +I E+L I
Sbjct: 111 NSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGI 170
Query: 124 ASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAV 183
+ D+AGATFMAA S+PELF + +G F+ ++G+G +VGSAVFN+L V CALF+ +
Sbjct: 171 SDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREI 230
Query: 184 IELDWWSVTRDCMMYXXXXXXLILTLLDDKIYWHEALLLVLMYTFYIL 231
+ L WW + RD Y LI+ LD+ I W E+LLL+ Y Y++
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVV 278
Score = 127 bits (306), Expect = 9e-29
Identities = 71/188 (37%), Positives = 108/188 (57%), Gaps = 11/188 (5%)
Query: 231 LEKINPLDASQRMTPRS-----VQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISF 285
+E N MTP S VQNG+L IE + + S+ ++P +
Sbjct: 412 IELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSL-AWPSETR-- 468
Query: 286 WKKLFWVLTWPIRLILWATIPDCRHRHS--IYPLTFIMCITWIGSVSYLVAWIITVVGDT 343
K++ +++ +PI LW T+PD R S +P+TF ITWI SYL+ W VG+T
Sbjct: 469 -KQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGET 527
Query: 344 LNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVK 403
+ + + I GLTILAAGTS+P+ ++SV+V ++G G M +S+S+GSN FDI + L LPWL+
Sbjct: 528 IGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLY 587
Query: 404 SLFYPSTP 411
++ + P
Sbjct: 588 TVIHRFQP 595
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 337 ITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCL 396
+TV+ + L + D + G T +AAG S PE +S++ H +GI +GS F+IL +
Sbjct: 161 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVI 220
Query: 397 GL 398
G+
Sbjct: 221 GM 222
Score = 37.5 bits (83), Expect = 0.090
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 119 ERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNV 169
E + I+ +I G T +AA +S P+L + + GD+ V + VGS +F++
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein.
Length = 218
Score = 143 bits (346), Expect = 1e-33
Identities = 58/122 (47%), Positives = 91/122 (74%), Gaps = 3/122 (2%)
Query: 287 KKLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTL 344
K++FWVL+ PI +L+ T PDCR + + + +TF M WI + +Y++ W++T+ G+TL
Sbjct: 22 KRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGETL 81
Query: 345 NVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKS 404
+PD++ GLT+LAAGTS+P+ ++SVLV ++G G M +SN +GSN FD +LCLG+PW +K+
Sbjct: 82 EIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFD-MLCLGIPWFIKT 140
Query: 405 LF 406
F
Sbjct: 141 AF 142
Score = 36.7 bits (81), Expect = 0.16
Identities = 18/59 (30%), Positives = 32/59 (54%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAV 172
+ I E L I + G T +AA +S P+ + + +GD+ + +VGS VF++L +
Sbjct: 74 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCL 132
>AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein
protein.
Length = 316
Score = 130 bits (314), Expect = 9e-30
Identities = 55/120 (45%), Positives = 84/120 (70%), Gaps = 2/120 (1%)
Query: 288 KLFWVLTWPIRLILWATIPDCRHRH--SIYPLTFIMCITWIGSVSYLVAWIITVVGDTLN 345
K+ WV TWP+ +L TIP+C + +TFI WI SY++ W++T++G TL
Sbjct: 118 KVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLG 177
Query: 346 VPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSL 405
+PD I G+T LAAGTS+P+ ++S++V +QG G M +SN+IGSN FDIL+ LG+PW ++++
Sbjct: 178 IPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTM 237
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 114 IEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVL 170
+ II L I I G TF+AA +S P+ + + GD+ V +GS VF++L
Sbjct: 169 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 225
>AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens
cDNA FLJ38852 fis, clone MESAN2010312, weakly similar to
Homo sapiens sodium/calcium exchanger NCKX3 (SLC24A3)
mRNA. ).
Length = 352
Score = 90.6 bits (215), Expect = 9e-18
Identities = 37/63 (58%), Positives = 51/63 (80%)
Query: 99 FLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGV 158
F L VC+D+FVP++E ICERL+++ D+AGATFMAA SS+PELF + +G F+T GD+GV
Sbjct: 2 FYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGV 61
Query: 159 GAV 161
G +
Sbjct: 62 GTI 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 288 KLFWVLTWPIRLILWATIPDCR--HRHSIYPLTFIMCITWIGSVSYLVAWI 336
K+ WV TWP+ +L TIP+ + +TFI WI SY++ W+
Sbjct: 276 KVKWVFTWPLIFLLCVTIPNSSKPRWEKFFMVTFITATLWIAVFSYIMVWL 326
Score = 37.5 bits (83), Expect = 0.090
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 205 LILTLLDDKIYWHEALLLVLMYTFYIL-EKIN-PLDASQRMTPRSVQNGD 252
LI+ + D++I W E L+L+++Y FYIL K N + A + +S+ NG+
Sbjct: 69 LIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTVKQKSIANGN 118
Score = 33.9 bits (74), Expect = 1.1
Identities = 14/40 (35%), Positives = 25/40 (62%)
Query: 342 DTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGI 381
+ L++ + + G T +AAG+S PE +SV+ HG +G+
Sbjct: 22 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGV 61
>M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein.
Length = 973
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 903
Score = 43.6 bits (98), Expect = 0.001
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + SV + GH G +G S +GS F++ + + L
Sbjct: 132 ETVSNLTLMALGSSAPEILLSV-IEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
>BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein.
Length = 335
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 166 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 225
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 226 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 265
>BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein.
Length = 384
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 215 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 274
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 275 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 314
>AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchanger
isoform NCX1.7 precursor protein.
Length = 960
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 890
Score = 43.6 bits (98), Expect = 0.001
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + SV + GH G +G S +GS F++ + + L
Sbjct: 132 ETVSNLTLMALGSSAPEILLSV-IEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
>AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchanger
isoform NaCa3 protein.
Length = 937
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 768 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 827
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 828 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 867
Score = 43.6 bits (98), Expect = 0.001
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + SV + GH G +G S +GS F++ + + L
Sbjct: 132 ETVSNLTLMALGSSAPEILLSV-IEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
>AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchanger
isoform NaCa7 protein.
Length = 960
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 890
Score = 43.6 bits (98), Expect = 0.001
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + SV + GH G +G S +GS F++ + + L
Sbjct: 132 ETVSNLTLMALGSSAPEILLSV-IEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
>AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8
(sodium/calcium exchanger), member 1 variant protein.
Length = 411
Score = 57.6 bits (133), Expect = 8e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEA-VSSVLVTKQGHG 377
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P+ S V T+ +
Sbjct: 242 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 301
Query: 378 TMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 302 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 341
>AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 298
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 112 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 169
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 170 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 218
>AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 284
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 98 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 155
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 156 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 204
>AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isoform
4 protein.
Length = 771
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 585 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 642
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 643 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 691
>AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 924
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 738 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 795
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 796 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 844
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 925
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 739 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 796
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 797 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 845
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 3 protein.
Length = 927
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 741 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 798
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 799 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 847
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 2 protein.
Length = 921
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 735 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 792
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 793 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 841
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 protein.
Length = 927
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 741 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 798
Query: 360 TSLPEAVSSVLVTKQG-HGTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S Q + I N GSN ++ L +GL W V ++++
Sbjct: 799 TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYW 847
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein.
Length = 952
Score = 52.4 bits (120), Expect = 3e-06
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ L+ + + G T+ + DS+ + +A G
Sbjct: 766 VLFACVPPTEYCHGW--ACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALG 823
Query: 360 TSLPEAVSSVLVTKQGH-GTMGISNSIGSNTFDILLCLGLPWLVKSLFY 407
TS+P+ +S + Q I N GSN ++ L LG+ W V ++++
Sbjct: 824 TSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYW 872
Score = 42.7 bits (96), Expect = 0.002
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G G+LG G +VGSA FN+ V A C
Sbjct: 159 VSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVC 211
>BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein.
Length = 584
Score = 50.4 bits (115), Expect = 1e-05
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
L F+ WI + + V I+ +G + +++ GLT+LA G S+ +A S + +QG+
Sbjct: 424 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 483
Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403
M S G F+IL+ +GL L++
Sbjct: 484 PRMAFSACFGGIIFNILVGVGLGCLLQ 510
Score = 49.6 bits (113), Expect = 2e-05
Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
+ L+ LY FL+LG +F P + I L ++ ++AG TF+A + +P++F V
Sbjct: 100 VTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALV 159
Query: 148 G-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
+ L +GA+ G+ V V + + RD + Y
Sbjct: 160 AFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASR--PFFRDIVFYMVAVFLTF 217
Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKI 234
L L ++ AL + +Y FY++ I
Sbjct: 218 LMLFRGRVTLAWALGYLGLYVFYVVTVI 245
>AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent
exchanger short splice isoform protein.
Length = 528
Score = 50.4 bits (115), Expect = 1e-05
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
L F+ WI + + V I+ +G + +++ GLT+LA G S+ +A S + +QG+
Sbjct: 368 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 427
Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403
M S G F+IL+ +GL L++
Sbjct: 428 PRMAFSACFGGIIFNILVGVGLGCLLQ 454
Score = 46.8 bits (106), Expect = 1e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
+ L+ LY FL+LG +F P + I L ++ ++AG TF+A + +P++F V
Sbjct: 100 VTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALV 159
Query: 148 G-TFVTEGDLGVGAV---VGSAVFNVLAVPACCALF 179
+ L +GA+ +G VF V+ V C ++
Sbjct: 160 AFSDPHTAGLALGALFGYLGLYVFYVVTVILCTWIY 195
>AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent
exchanger protein.
Length = 584
Score = 50.4 bits (115), Expect = 1e-05
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
L F+ WI + + V I+ +G + +++ GLT+LA G S+ +A S + +QG+
Sbjct: 424 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 483
Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403
M S G F+IL+ +GL L++
Sbjct: 484 PRMAFSACFGGIIFNILVGVGLGCLLQ 510
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 88 ILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCV 147
+ L+ LY FL+LG +F P + I L ++ ++AG TF+A + +P++F V
Sbjct: 100 VTLYVSWLLYLFLILGVTAAKFFCPNLSAIPTTLKLSHNVAGVTFLAFGNGAPDIFSALV 159
Query: 148 G-TFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYXXXXXXLI 206
+ L +GA+ G+ V V + + RD + Y
Sbjct: 160 AFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASR--PFFRDIVFYMVAVFLTF 217
Query: 207 LTLLDDKIYWHEALLLVLMYTFYILEKI 234
L L ++ AL + +Y FY++ I
Sbjct: 218 LMLFRGRVTLAWALGYLGLYVFYVVTVI 245
>AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22233 fis, clone HRC02016. ).
Length = 389
Score = 50.4 bits (115), Expect = 1e-05
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 317 LTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGH 376
L F+ WI + + V I+ +G + +++ GLT+LA G S+ +A S + +QG+
Sbjct: 229 LGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGY 288
Query: 377 GTMGISNSIGSNTFDILLCLGLPWLVK 403
M S G F+IL+ +GL L++
Sbjct: 289 PRMAFSACFGGIIFNILVGVGLGCLLQ 315
>AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein.
Length = 603
Score = 43.6 bits (98), Expect = 0.001
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G T GDLG +VGSA FN+ + A C
Sbjct: 134 VSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALC 186
Score = 33.1 bits (72), Expect = 1.9
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + SV + GH G +G S +GS F++ + + L
Sbjct: 132 ETVSNLTLMALGSSAPEILLSV-IEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
>AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 4 protein.
Length = 620
Score = 39.5 bits (88), Expect = 0.022
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 127 IAGATFMAAASSSPELFINCV---GTFVTEGDLGVGAVVGSAVFNVLAVPACC 176
++ T MA SS+PE+ ++ + G GDLG +VGSA FN+ + C
Sbjct: 133 VSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGIC 185
Score = 34.7 bits (76), Expect = 0.63
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 5/55 (9%)
Query: 348 DSITGLTILAAGTSLPEAVSSVLVTKQGH----GTMGISNSIGSNTFDILLCLGL 398
++++ LT++A G+S PE + S L+ GH G +G S +GS F++ + +G+
Sbjct: 131 ETVSNLTLMALGSSAPEILLS-LIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184
>BC114217-1|AAI14218.1| 210|Homo sapiens SLC8A3 protein protein.
Length = 210
Score = 35.1 bits (77), Expect = 0.48
Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ ++ + + G T+ + DS+T + +A G
Sbjct: 98 VLFACVPPTEYCHGW--ACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG 155
Query: 360 TSLPEAVSSVLVTKQG 375
TS+P L ++G
Sbjct: 156 TSVPGESERCLNLQRG 171
>AC007377-1|AAX81985.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 33.5 bits (73), Expect = 1.5
Identities = 15/45 (33%), Positives = 27/45 (60%)
Query: 319 FIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLP 363
FI+ I IG ++ + + + G T+ + DS+T + +A GTS+P
Sbjct: 201 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVP 245
>AL513323-4|CAI15595.1| 329|Homo sapiens olfactory receptor, family
10, subfamily J, member 3 protein.
Length = 329
Score = 32.3 bits (70), Expect = 3.4
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 70 ILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSV 105
+ EF +G + F+RQH + FL LY L G+V
Sbjct: 9 VTEFLFEGFSSFRRQHKLVFFVVFLTLYLLTLSGNV 44
>AL512764-1|CAC21681.1| 793|Homo sapiens hypothetical protein
protein.
Length = 793
Score = 32.3 bits (70), Expect = 3.4
Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 300 ILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAG 359
+L+A +P + H F + I IG ++ L+ + + G T+ + DS+ + +A G
Sbjct: 531 VLFACVPPTEYCHGW--ACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALG 588
Query: 360 TSLP 363
TS+P
Sbjct: 589 TSIP 592
>AC007254-1|AAF19235.1| 124|Homo sapiens unknown protein.
Length = 124
Score = 31.9 bits (69), Expect = 4.5
Identities = 13/51 (25%), Positives = 26/51 (50%)
Query: 367 SSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVT 417
S V T+ + I N GSN ++ L +G+ W + ++++ + E V+
Sbjct: 4 SKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS 54
>BC130437-1|AAI30438.1| 504|Homo sapiens DMRT-like family A1
protein.
Length = 504
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLF 290
+PRS+ + DLE G E D T + S +V S P D + K+F
Sbjct: 291 SPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIF 337
>BC130435-1|AAI30436.1| 504|Homo sapiens DMRT-like family A1
protein.
Length = 504
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLF 290
+PRS+ + DLE G E D T + S +V S P D + K+F
Sbjct: 291 SPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIF 337
>AY424283-1|AAR08371.1| 330|Homo sapiens progestin and adipoQ
receptor family member V protein.
Length = 330
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 254 ERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKL--FWVLTWPIRLILWATIPDCRHR 311
E+GI RH + + S++ + ++ W L FW W L+ T D ++
Sbjct: 21 EQGILFGYRHPQSSATACILSLFQMTNETLNIWTHLLPFWFFAWRFVTALYMT--DIKND 78
Query: 312 HSIYPLTFIMCITWI 326
+P+ MC + +
Sbjct: 79 SYSWPMLVYMCTSCV 93
>AL161730-1|CAH73857.1| 504|Homo sapiens DMRT-like family A1
protein.
Length = 504
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLF 290
+PRS+ + DLE G E D T + S +V S P D + K+F
Sbjct: 291 SPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIF 337
>AK096011-1|BAC04672.1| 504|Homo sapiens protein ( Homo sapiens
cDNA FLJ38692 fis, clone KIDNE2001713, weakly similar to
Oreochromis niloticus sex-determining protein DMO mRNA.
).
Length = 504
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLF 290
+PRS+ + DLE G E D T + S +V S P D + K+F
Sbjct: 291 SPRSLSSSDLESGNESEWVKDLTSTKASLPTVSSRPRDPLDILTKIF 337
>AK000197-1|BAA91004.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ20190 fis, clone COLF0714. ).
Length = 330
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 254 ERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKL--FWVLTWPIRLILWATIPDCRHR 311
E+GI RH + + S++ + ++ W L FW W L+ T D ++
Sbjct: 21 EQGILFGYRHPQSSATACILSLFQMTNETLNIWTHLLPFWFFAWRFVTALYMT--DIKND 78
Query: 312 HSIYPLTFIMCITWI 326
+P+ MC + +
Sbjct: 79 SYSWPMLVYMCTSCV 93
>AJ290954-1|CAC16590.1| 263|Homo sapiens putative DMO orthologue
protein.
Length = 263
Score = 31.1 bits (67), Expect = 7.8
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 244 TPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLF 290
+PRS+ + DLE G E D T + S +V S P D + K+F
Sbjct: 194 SPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIF 240
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.327 0.141 0.449
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 64,383,162
Number of Sequences: 224733
Number of extensions: 2746136
Number of successful extensions: 11568
Number of sequences better than 10.0: 65
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 11328
Number of HSP's gapped (non-prelim): 194
length of query: 427
length of database: 73,234,838
effective HSP length: 92
effective length of query: 335
effective length of database: 52,559,402
effective search space: 17607399670
effective search space used: 17607399670
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 67 (31.1 bits)
- SilkBase 1999-2023 -