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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000686-TA|BGIBMGA000686-PA|IPR005399|KCNAB voltage-gated
K+ channel, beta subunit, IPR001395|Aldo/keto reductase
         (529 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.)              55   1e-07
SB_51365| Best HMM Match : ig (HMM E-Value=0.00037)                    53   5e-07
SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1)              48   2e-05
SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0)                46   8e-05
SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.)               46   8e-05
SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   4e-04
SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0)                 42   0.001
SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16)             39   0.011
SB_3970| Best HMM Match : Drf_FH1 (HMM E-Value=1.2)                    31   2.3  
SB_45482| Best HMM Match : BTB (HMM E-Value=5.6e-11)                   31   3.0  
SB_21418| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   3.0  
SB_49745| Best HMM Match : A2M_comp (HMM E-Value=0)                    30   4.0  
SB_2841| Best HMM Match : No HMM Matches (HMM E-Value=.)               30   4.0  
SB_39858| Best HMM Match : Spectrin (HMM E-Value=2.6e-05)              29   7.0  
SB_226| Best HMM Match : Tektin (HMM E-Value=0)                        29   7.0  
SB_53736| Best HMM Match : Borrelia_orfA (HMM E-Value=0.64)            29   9.3  
SB_3573| Best HMM Match : DUF1168 (HMM E-Value=1)                      29   9.3  

>SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 394

 Score = 55.2 bits (127), Expect = 1e-07
 Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 19/163 (11%)

Query: 127 EESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFH 186
           E   EDV + AL+NG  + D ++ +  + E E+G  ++K  ++R  I +TTK+  S + H
Sbjct: 43  ETGCEDVCLFALKNGYRMLDTADIY--QNEKEVGSAVRKSGLKREDIYVTTKLKPSEEGH 100

Query: 187 TNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGW 246
           +N        + K+  ES+K    +L + Y+D+ L+H   P   +     ++  +  EG 
Sbjct: 101 SN--------ALKYAKESIK----KLDIGYVDLFLIHTPRPGNIIAAYDALLT-LKEEGL 147

Query: 247 VMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
           +   G + +    + +     R+  C TP + Q E + F R++
Sbjct: 148 IRSVGVSNFGVHHLEE----LRKAGCRTPAINQIEINPFWRQE 186


>SB_51365| Best HMM Match : ig (HMM E-Value=0.00037)
          Length = 498

 Score = 53.2 bits (122), Expect = 5e-07
 Identities = 35/139 (25%), Positives = 67/139 (48%), Gaps = 4/139 (2%)

Query: 148 SEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDER---GLSRKHVIES 204
           S AH +   A + +++   +       I+  +   T+ HT + S  R   GL    V+E 
Sbjct: 284 SSAHISNTRAVVKQLMPSTSATPHPTTISLVVANGTQ-HTPSGSRNRVAGGLKFDRVLEQ 342

Query: 205 VKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
           +  SL R++ + +D+  LH  D   P+EE ++ ++ +  EG    +G + ++  E+ + Y
Sbjct: 343 MNTSLKRMKRDKVDIFYLHAPDHKTPIEESLKAVDQLHKEGKFKEFGLSNYAAWEVAEIY 402

Query: 265 TNCRQFNCITPIVEQTEYH 283
             C+  N I P + Q  Y+
Sbjct: 403 YLCKANNYILPTLYQGMYN 421


>SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1)
          Length = 93

 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/88 (29%), Positives = 48/88 (54%), Gaps = 4/88 (4%)

Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
           G ++P  GLGL+  L E+  +  V+ ALENG  + D + ++    E  +G  L++  V R
Sbjct: 6   GYKIPRFGLGLYD-LDEKHTKQAVLWALENGYRMIDTAASY--NNEKRVGEALRESAVPR 62

Query: 171 TSIIITTKIYWSTK-FHTNNRSDERGLS 197
           + + + TK+Y +   +    ++ +R LS
Sbjct: 63  SEVYLVTKVYHTDHGYEKTMKAYDRSLS 90


>SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0)
          Length = 333

 Score = 46.0 bits (104), Expect = 8e-05
 Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 23/179 (12%)

Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
           G ++P +GLG   + S+++    V+ ALE+G  L D +  +    E  +G  ++  N+ R
Sbjct: 73  GRKIPLLGLGAHDIHSKQA----VLWALESGYRLIDTASRY--HNEQSVGEAVRCSNIPR 126

Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCP 230
             I + TK+Y++          E G   K  +++   SL RL + Y+D+ L+H   P   
Sbjct: 127 CEIYVVTKVYFT----------EHGY--KETMDAFYKSLTRLGLGYVDLYLIHFPVPSGV 174

Query: 231 MEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
           +    + M  + + G +   G + ++   +       RQ   + P V Q E H F + K
Sbjct: 175 VGSW-QAMIDLRSRGLIRSIGVSNFNIQHL----EALRQQTGVVPAVNQIEVHPFLQMK 228


>SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 619

 Score = 46.0 bits (104), Expect = 8e-05
 Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 15/114 (13%)

Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
           SG  +P +G G  T L E+++  VV TALE G  L D ++ +    E ++ + +    + 
Sbjct: 333 SGYTMPVMGFGTAT-LGEDTLS-VVKTALETGYRLIDTAQGY-PLSEPQVAKAIADSGIP 389

Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
           R  I I TK++             R L  +  ++SV+ SL  L  +YID+ L+H
Sbjct: 390 RKDIFIITKLH------------PRYLGYEPTLKSVEMSLRALSTDYIDLFLIH 431


>SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 340

 Score = 43.6 bits (98), Expect = 4e-04
 Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 18/117 (15%)

Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKK---R 166
           +GL +P +GLG W       +E+ V  A++ G    D + A+  + E E+G  L++    
Sbjct: 8   NGLEMPVLGLGTWKS-KPGQVENAVKFAIKEGYRHIDCAYAY--RNEKEVGDALRELLGS 64

Query: 167 NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
            V R  + IT+K+ W+TK   +N  D     R + ++S+K  LG   ++Y+D+ L+H
Sbjct: 65  VVERKDLFITSKL-WNTK---HNPKD----VRSNCVDSLK-DLG---LDYLDLYLIH 109


>SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0)
          Length = 407

 Score = 41.9 bits (94), Expect = 0.001
 Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 14/100 (14%)

Query: 126 SEESIEDVVMTALENGINLFDLSEAHCAKGEA--ELGRILKKRNVRRTSIIITTKIYWST 183
           S+E + + V  A+E G    D +E +  +GE    L  +L +  V+R  + +T+K+ W  
Sbjct: 63  SKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEGKVKREELFVTSKL-WCD 121

Query: 184 KFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
             H ++           V+ + +A+L  LQ++Y+D+ L+H
Sbjct: 122 SHHPDD-----------VLPACQATLKNLQLDYLDLYLIH 150


>SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16)
          Length = 195

 Score = 38.7 bits (86), Expect = 0.011
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
           S   ++ S + SL RL ++ ID+ LLH    V P+EE V     +++EG +  WG +   
Sbjct: 40  SEMKMMLSCEKSLERLGIDRIDLYLLHWEGRV-PLEETVDAFRELVDEGMIARWGVSNLD 98

Query: 257 PSEIMDAYTNCRQFNCITPIVEQ 279
             + ++  + CR  +    +V Q
Sbjct: 99  LGDPLE--STCRHASLALAVVLQ 119


>SB_3970| Best HMM Match : Drf_FH1 (HMM E-Value=1.2)
          Length = 558

 Score = 31.1 bits (67), Expect = 2.3
 Identities = 14/40 (35%), Positives = 24/40 (60%)

Query: 4   KGVEGGGKEGSQMSRSESTVSRCTPHTPLGLPDSASVDSN 43
           K  EGGG EG+   +S S+ +  TP  P+ + +  ++DS+
Sbjct: 319 KKEEGGGLEGTTQRQSVSSSTSSTPKEPIPIKEVLAMDSS 358


>SB_45482| Best HMM Match : BTB (HMM E-Value=5.6e-11)
          Length = 3037

 Score = 30.7 bits (66), Expect = 3.0
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 399  MRSSGSKEQVTGE---EPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNC 450
            +R +  KE+V G    EPR    K +  + L+N     + +  V  C K+ESVNC
Sbjct: 1228 LRGNNDKEEVVGAQNIEPRKDNVKDQITSELSNKRKLIVDEENVGNCDKDESVNC 1282


>SB_21418| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 887

 Score = 30.7 bits (66), Expect = 3.0
 Identities = 29/146 (19%), Positives = 62/146 (42%), Gaps = 5/146 (3%)

Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
           G  L + N +   ++ITT+  +ST  +T+N  +   L + + ++    S  RL +   ++
Sbjct: 43  GTKLCENNSQHLPVLITTRHDYSTSANTHNARNSSNLLKINSVKITPDSAPRLHLATWNI 102

Query: 220 -VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
             +  K   +C +    R+    + E W+     ++   + + D  T     NC  P V 
Sbjct: 103 RAMNRKAASICDLVISKRIDVLALVETWLTAENNSK--STVVEDTSTRLPVPNCSDPTVA 160

Query: 279 QTEYHMFCREKPELYMPELYHKIGVG 304
               ++  R+   +++P      G+G
Sbjct: 161 DVINNL--RDFDFIHLPRAGRGGGIG 184


>SB_49745| Best HMM Match : A2M_comp (HMM E-Value=0)
          Length = 1079

 Score = 30.3 bits (65), Expect = 4.0
 Identities = 13/47 (27%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 103  RYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSE 149
            RYK  GK+G+ + ++G+     + E S+++ +   +E  I  +++SE
Sbjct: 959  RYKKAGKTGMAIIDVGVFTGFAVDERSLKE-LQKKMEGSIGKYEISE 1004


>SB_2841| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3297

 Score = 30.3 bits (65), Expect = 4.0
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 169 RRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
           R+TS++      W      ++ S+E  L RKH+ E ++A LGR
Sbjct: 648 RKTSLMSRYMWQWDRSSGLDSDSEEDLLDRKHLQEFIQAELGR 690


>SB_39858| Best HMM Match : Spectrin (HMM E-Value=2.6e-05)
          Length = 3397

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 158  ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
            E GR++++R VRRT   +TTK   +T+  T++++    +  K V+ES +   G    E  
Sbjct: 2064 EEGRVVRRRIVRRT---VTTKTL-TTRTVTSDQAGPEEMPTKEVLESAEPVKGTEVPEEG 2119

Query: 218  DV 219
            DV
Sbjct: 2120 DV 2121


>SB_226| Best HMM Match : Tektin (HMM E-Value=0)
          Length = 534

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 3/69 (4%)

Query: 358 SAITTGKGLGREEITGLFAKSRFNRKYSTFSWCEEDLAVPEMRSSGSKEQVTGEEPRTYG 417
           S I  G   G E +      SR   KYS   W   ++      SSG KE+ T E  R   
Sbjct: 65  SKILNGSSSGLEHLPYTAVSSRAIHKYSPQQWRSSNMLNV---SSGEKERATAERLRDEC 121

Query: 418 DKLRDLANL 426
            +LR   +L
Sbjct: 122 SRLRTETSL 130


>SB_53736| Best HMM Match : Borrelia_orfA (HMM E-Value=0.64)
          Length = 520

 Score = 29.1 bits (62), Expect = 9.3
 Identities = 25/123 (20%), Positives = 58/123 (47%), Gaps = 10/123 (8%)

Query: 371 ITGLFAKSRFNRKYSTFSWCEEDLAVPEMRSSGSKEQVTGEEPRTYGDKLRDLANLANSL 430
           +T LF+KSR + ++      + + A+ ++ ++ +++Q    EP+   D + D   L N++
Sbjct: 3   LTFLFSKSRIDEEFKRRVLAKYEQAIDDIDANAARDQAL--EPQELRDTITDSTELENAI 60

Query: 431 NCSMSQLAVAWCLK----NESVNCLLLGATSVEQFKENIHALQVYIKKIFKVCVKSFKLL 486
               ++ +     K     E V   LL  + + + + N    Q+  K +  V   + +LL
Sbjct: 61  ESLHTKFSKRMSFKLTELQEEVGNDLLTDSGLSEEEAN----QIVAKLMANVAATNKRLL 116

Query: 487 QQS 489
           +++
Sbjct: 117 EEA 119


>SB_3573| Best HMM Match : DUF1168 (HMM E-Value=1)
          Length = 782

 Score = 29.1 bits (62), Expect = 9.3
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 158 ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
           E GR++K+R VRRT   +TTK   +T+  T++++    +  + V+ES +   G    E  
Sbjct: 595 EEGRVVKRRIVRRT---VTTKTL-TTRTVTSDQAGPEEMPTEEVLESAEPVKGTEVPEEG 650

Query: 218 DV 219
           DV
Sbjct: 651 DV 652


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.320    0.135    0.409 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 17,408,478
Number of Sequences: 59808
Number of extensions: 704466
Number of successful extensions: 1534
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1523
Number of HSP's gapped (non-prelim): 19
length of query: 529
length of database: 16,821,457
effective HSP length: 85
effective length of query: 444
effective length of database: 11,737,777
effective search space: 5211572988
effective search space used: 5211572988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 62 (29.1 bits)

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