Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000686-TA|BGIBMGA000686-PA|IPR005399|KCNAB voltage-gated
K+ channel, beta subunit, IPR001395|Aldo/keto reductase
(529 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 345 2e-93
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 330 5e-89
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 248 4e-64
UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 241 4e-62
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 240 7e-62
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 202 2e-50
UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 173 7e-42
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 163 8e-39
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 157 9e-37
UniRef50_Q5D8T1 Cluster: SJCHGC06048 protein; n=1; Schistosoma j... 155 3e-36
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 153 8e-36
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 145 2e-33
UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 142 2e-32
UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 138 3e-31
UniRef50_A0DXM3 Cluster: Chromosome undetermined scaffold_69, wh... 138 4e-31
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 136 2e-30
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 134 7e-30
UniRef50_Q39EI1 Cluster: Aldo/keto reductase; n=12; Burkholderia... 132 2e-29
UniRef50_UPI00006CB156 Cluster: oxidoreductase, aldo/keto reduct... 125 3e-27
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 124 4e-27
UniRef50_Q9PGD5 Cluster: Voltage-gated potassium channel beta su... 122 2e-26
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 109 1e-22
UniRef50_Q4TBS9 Cluster: Chromosome undetermined SCAF7094, whole... 108 3e-22
UniRef50_Q4RV93 Cluster: Chromosome 15 SCAF14992, whole genome s... 107 1e-21
UniRef50_Q5K978 Cluster: Aryl-alcohol dehydrogenase, putative; n... 106 1e-21
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 105 3e-21
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 105 4e-21
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 103 2e-20
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 101 5e-20
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 99 3e-19
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 99 3e-19
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 99 3e-19
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 97 1e-18
UniRef50_A1CYI6 Cluster: Oxidoreductase; n=15; cellular organism... 95 4e-18
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 92 3e-17
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 91 5e-17
UniRef50_A5DEF4 Cluster: Putative uncharacterized protein; n=1; ... 90 1e-16
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 90 2e-16
UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 89 2e-16
UniRef50_Q3VZ80 Cluster: Aldo/keto reductase precursor; n=1; Fra... 89 4e-16
UniRef50_Q82PN0 Cluster: Putative oxidoreductase; n=1; Streptomy... 88 6e-16
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 87 8e-16
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 87 8e-16
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 87 1e-15
UniRef50_A4FC65 Cluster: Oxidoreductase, aldo/keto reductase fam... 86 2e-15
UniRef50_Q2UT23 Cluster: Voltage-gated shaker-like K+ channel; n... 86 2e-15
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 86 3e-15
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 85 3e-15
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 85 4e-15
UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 85 6e-15
UniRef50_Q15JF3 Cluster: Putative oxidoreductase; n=1; Streptomy... 84 8e-15
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 84 8e-15
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 84 1e-14
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 84 1e-14
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 83 1e-14
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 83 2e-14
UniRef50_A1CWM8 Cluster: Aldo-keto reductase, putative; n=14; As... 83 2e-14
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 83 2e-14
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 83 2e-14
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 81 5e-14
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 81 5e-14
UniRef50_A6WAF9 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 81 5e-14
UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 81 5e-14
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 81 7e-14
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 81 7e-14
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 81 9e-14
UniRef50_Q6FV29 Cluster: Similar to tr|Q02895 Saccharomyces cere... 81 9e-14
UniRef50_Q02895 Cluster: Putative aryl-alcohol dehydrogenase YPL... 81 9e-14
UniRef50_A7TRU8 Cluster: Putative uncharacterized protein; n=1; ... 80 1e-13
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 80 2e-13
UniRef50_Q13PH6 Cluster: Putative oxidoreductase; n=1; Burkholde... 80 2e-13
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 80 2e-13
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 79 2e-13
UniRef50_Q0LSA5 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 79 2e-13
UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n... 79 2e-13
UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductas... 79 4e-13
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 79 4e-13
UniRef50_A6VR43 Cluster: Aldo/keto reductase precursor; n=3; Pas... 78 5e-13
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 78 7e-13
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 77 9e-13
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 77 1e-12
UniRef50_Q9S0N9 Cluster: DTDP-4-keto-6-deoxy-L-hexose 2,3-reduct... 77 2e-12
UniRef50_Q11BF4 Cluster: Twin-arginine translocation pathway sig... 77 2e-12
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 77 2e-12
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 77 2e-12
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 76 3e-12
UniRef50_Q9HPH9 Cluster: Aryl-alcohol dehydrogenase; n=3; Haloba... 76 3e-12
UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep... 75 4e-12
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 75 4e-12
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 75 4e-12
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 75 5e-12
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 75 6e-12
UniRef50_Q1YGH2 Cluster: Putative aldo/keto reductase; n=1; Aura... 74 8e-12
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 74 8e-12
UniRef50_A6VL42 Cluster: Aldo/keto reductase; n=3; Pasteurellace... 74 1e-11
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 73 1e-11
UniRef50_Q75ZG2 Cluster: Aldo-keto reductase; n=10; Pezizomycoti... 73 2e-11
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 73 3e-11
UniRef50_Q64UL3 Cluster: Aldo/keto reductase family oxidoreducta... 73 3e-11
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 73 3e-11
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 73 3e-11
UniRef50_Q2S286 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 3e-11
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 72 3e-11
UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 72 4e-11
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 71 6e-11
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 71 8e-11
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 71 8e-11
UniRef50_A1WAL7 Cluster: Aldo/keto reductase; n=35; cellular org... 71 8e-11
UniRef50_Q747Y9 Cluster: Oxidoreductase, aldo/keto reductase fam... 71 1e-10
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 71 1e-10
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 70 1e-10
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 70 1e-10
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 70 2e-10
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 70 2e-10
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 69 3e-10
UniRef50_Q7NFR4 Cluster: Gll3460 protein; n=5; Bacteria|Rep: Gll... 69 4e-10
UniRef50_Q0LP92 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 69 4e-10
UniRef50_A3US12 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 4e-10
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 69 4e-10
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 69 4e-10
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 69 4e-10
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 5e-10
UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 5e-10
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 5e-10
UniRef50_Q1IH94 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:... 68 5e-10
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 68 5e-10
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 68 7e-10
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 67 9e-10
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 67 1e-09
UniRef50_Q0UI32 Cluster: Putative uncharacterized protein; n=1; ... 67 1e-09
UniRef50_Q3WFM1 Cluster: Aldo/keto reductase:Bacterial regulator... 66 2e-09
UniRef50_Q5TG84 Cluster: Potassium voltage-gated channel, shaker... 66 2e-09
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 66 2e-09
UniRef50_Q1NH47 Cluster: Rhizopine catabolism protein; n=7; Prot... 66 2e-09
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 66 2e-09
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 66 2e-09
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 66 2e-09
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 66 3e-09
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 66 3e-09
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 65 4e-09
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 64 7e-09
UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 64 7e-09
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 64 7e-09
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 64 9e-09
UniRef50_A5CUU8 Cluster: Putative oxidoreductase; n=1; Clavibact... 64 9e-09
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 64 1e-08
UniRef50_Q8NQC2 Cluster: Predicted oxidoreductases; n=5; Coryneb... 64 1e-08
UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc... 64 1e-08
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 64 1e-08
UniRef50_A5G9P4 Cluster: Aldo/keto reductase precursor; n=1; Geo... 64 1e-08
UniRef50_A4AHH2 Cluster: Oxidoreductase; n=3; Actinobacteria (cl... 64 1e-08
UniRef50_O25804 Cluster: Aldo-keto reductase, putative; n=5; Pro... 63 2e-08
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 63 2e-08
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 63 2e-08
UniRef50_Q9HI90 Cluster: NDP-hexose 2, 3-enoyl reductase TylCII ... 63 2e-08
UniRef50_A7D4B7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 63 2e-08
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 63 2e-08
UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib... 62 3e-08
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 62 3e-08
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 62 3e-08
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 62 3e-08
UniRef50_A4III4 Cluster: Kcnab2 protein; n=2; Euteleostomi|Rep: ... 62 4e-08
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 62 4e-08
UniRef50_Q1FMI0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 62 4e-08
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 62 4e-08
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 62 4e-08
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 62 4e-08
UniRef50_O34185 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R... 62 4e-08
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 62 5e-08
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 62 5e-08
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 62 5e-08
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 62 5e-08
UniRef50_Q4TA27 Cluster: Chromosome undetermined SCAF7470, whole... 61 6e-08
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 61 6e-08
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 61 6e-08
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 61 6e-08
UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 61 6e-08
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 61 6e-08
UniRef50_A4WGJ6 Cluster: Aldo/keto reductase precursor; n=4; Bac... 61 6e-08
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 6e-08
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 61 6e-08
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 61 6e-08
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 61 8e-08
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 61 8e-08
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 61 8e-08
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 61 8e-08
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 61 8e-08
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 8e-08
UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 60 1e-07
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 60 1e-07
UniRef50_A6LCA8 Cluster: Aldo/keto reductase; n=3; Bacteroidales... 60 1e-07
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07
UniRef50_A7Q5Z6 Cluster: Chromosome chr14 scaffold_54, whole gen... 60 1e-07
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 60 2e-07
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 60 2e-07
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 60 2e-07
UniRef50_A3YG17 Cluster: Oxidoreductase; n=1; Marinomonas sp. ME... 60 2e-07
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 60 2e-07
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 60 2e-07
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 2e-07
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 59 2e-07
UniRef50_Q03X89 Cluster: Aryl-alcohol dehydrogenase family enzym... 59 2e-07
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 59 2e-07
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 59 3e-07
UniRef50_A2QBJ9 Cluster: Remark: AFAR is a protein in rat liver ... 59 3e-07
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 59 3e-07
UniRef50_Q00258 Cluster: Norsolorinic acid reductase; n=17; Dika... 59 3e-07
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 58 4e-07
UniRef50_Q39G79 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 58 4e-07
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 58 4e-07
UniRef50_A6WDF5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 58 4e-07
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 58 4e-07
UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 58 6e-07
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 6e-07
UniRef50_Q82LM1 Cluster: Putative aryl-alcohol dehydrogenase; n=... 58 6e-07
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 6e-07
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 58 6e-07
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 58 8e-07
UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta... 58 8e-07
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 57 1e-06
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 57 1e-06
UniRef50_Q5FK30 Cluster: Aldo-keto oxidoreductase; n=3; Bacteria... 57 1e-06
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 57 1e-06
UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri... 57 1e-06
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 1e-06
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 57 1e-06
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 57 1e-06
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 56 2e-06
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 56 2e-06
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 56 2e-06
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 56 2e-06
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 56 2e-06
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 56 2e-06
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 56 2e-06
UniRef50_Q0CZ87 Cluster: Norsolorinic acid reductase; n=1; Asper... 56 2e-06
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 56 3e-06
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 56 3e-06
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 56 3e-06
UniRef50_A5FGY2 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 56 3e-06
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 56 3e-06
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 55 4e-06
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 55 4e-06
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 55 5e-06
UniRef50_A3XNV0 Cluster: Aldo/keto reductase family protein; n=1... 55 5e-06
UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila pseudoobscu... 55 5e-06
UniRef50_A2QN65 Cluster: Function: A. parasiticus norA has norso... 55 5e-06
UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 55 5e-06
UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus Ni... 55 5e-06
UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce... 55 5e-06
UniRef50_Q8A8Q2 Cluster: Aldo/keto reductase; n=3; Bacteroidales... 54 7e-06
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 54 7e-06
UniRef50_Q3Y3S0 Cluster: Aldo/keto reductase; n=1; Enterococcus ... 54 7e-06
UniRef50_A6VSN1 Cluster: Aldo/keto reductase; n=8; Proteobacteri... 54 7e-06
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 54 7e-06
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 54 7e-06
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 54 7e-06
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 54 7e-06
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 54 9e-06
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 54 9e-06
UniRef50_Q9F825 Cluster: TDP-4-keto-6-deoxyglucose 2,3 dehydrata... 54 9e-06
UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 54 9e-06
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 54 9e-06
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 54 9e-06
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 1e-05
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 54 1e-05
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 54 1e-05
UniRef50_Q8A1P5 Cluster: Putative oxidoreductase; n=3; Bacteroid... 53 2e-05
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 53 2e-05
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 53 2e-05
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 2e-05
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 53 2e-05
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 53 2e-05
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 53 2e-05
UniRef50_Q5DG65 Cluster: SJCHGC04213 protein; n=1; Schistosoma j... 53 2e-05
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 53 2e-05
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 53 2e-05
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 53 2e-05
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 52 3e-05
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 3e-05
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 52 3e-05
UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21... 52 3e-05
UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 52 3e-05
UniRef50_A0YA12 Cluster: Sugar-phosphate dehydrogenase; n=1; mar... 52 3e-05
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 52 3e-05
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 52 4e-05
UniRef50_A6FYD6 Cluster: Putative aldo/keto reductase; n=1; Ples... 52 4e-05
UniRef50_A5V047 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 52 4e-05
UniRef50_Q23TY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 4e-05
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 52 4e-05
UniRef50_Q98G15 Cluster: Mll3531 protein; n=3; Bacteria|Rep: Mll... 52 5e-05
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 52 5e-05
UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 52 5e-05
UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 52 5e-05
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 51 7e-05
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 51 7e-05
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 51 7e-05
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 51 9e-05
UniRef50_Q2RWD2 Cluster: Aldo/keto reductase; n=1; Rhodospirillu... 51 9e-05
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 51 9e-05
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 51 9e-05
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 51 9e-05
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 9e-05
UniRef50_A5BAI3 Cluster: Putative uncharacterized protein; n=2; ... 51 9e-05
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 50 1e-04
UniRef50_Q9KZ45 Cluster: Putative oxidoreductase; n=3; Bacteria|... 50 1e-04
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 50 1e-04
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-04
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 50 1e-04
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 50 1e-04
UniRef50_Q9HNN3 Cluster: General stress protein 69; n=5; Halobac... 50 1e-04
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 50 1e-04
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 50 2e-04
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 50 2e-04
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 50 2e-04
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 50 2e-04
UniRef50_Q0SFJ5 Cluster: Aryl-alcohol dehydrogenase; n=4; Actino... 50 2e-04
UniRef50_Q08VS2 Cluster: Twin-arginine translocation pathway sig... 50 2e-04
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 50 2e-04
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 50 2e-04
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 50 2e-04
UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox... 50 2e-04
UniRef50_Q2USD3 Cluster: Voltage-gated shaker-like K+ channel; n... 50 2e-04
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 50 2e-04
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 50 2e-04
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 50 2e-04
UniRef50_A6P1K7 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04
UniRef50_A6NRH9 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 50 2e-04
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 50 2e-04
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 50 2e-04
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 50 2e-04
UniRef50_Q8Y8L9 Cluster: Lmo0878 protein; n=12; Listeria|Rep: Lm... 49 3e-04
UniRef50_Q82GZ5 Cluster: Putative uncharacterized protein; n=1; ... 49 3e-04
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 49 3e-04
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 49 3e-04
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 49 3e-04
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 49 3e-04
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 49 3e-04
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 49 3e-04
UniRef50_Q4R9Q7 Cluster: Chromosome undetermined SCAF25547, whol... 49 4e-04
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 49 4e-04
UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 49 4e-04
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 49 4e-04
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 48 5e-04
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 48 5e-04
UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ... 48 5e-04
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 48 5e-04
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 48 5e-04
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 48 5e-04
UniRef50_Q1PBI2 Cluster: L-galactose dehydrogenase; n=15; Magnol... 48 5e-04
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 48 5e-04
UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 48 5e-04
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 48 5e-04
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 48 5e-04
UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 48 5e-04
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 48 5e-04
UniRef50_Q07747 Cluster: Probable aryl-alcohol dehydrogenase AAD... 48 5e-04
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 48 6e-04
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 48 6e-04
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 48 6e-04
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 48 6e-04
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 48 6e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 48 6e-04
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 48 8e-04
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 48 8e-04
UniRef50_Q5WEI0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 48 8e-04
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 48 8e-04
UniRef50_A6NS61 Cluster: Putative uncharacterized protein; n=1; ... 48 8e-04
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 48 8e-04
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 8e-04
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 48 8e-04
UniRef50_A2R5N3 Cluster: Function: A. parasiticus norA has norso... 48 8e-04
UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ... 48 8e-04
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 48 8e-04
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 47 0.001
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 47 0.001
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 47 0.001
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 47 0.001
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 47 0.001
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001
UniRef50_A6RHV7 Cluster: Putative uncharacterized protein; n=2; ... 47 0.001
UniRef50_Q01752 Cluster: Aryl-alcohol dehydrogenase [NADP+]; n=7... 47 0.001
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 47 0.001
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 47 0.001
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 47 0.001
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 47 0.001
UniRef50_Q2AQ04 Cluster: Aldo/keto reductase; n=7; Bacillus cere... 47 0.001
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 47 0.001
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 47 0.001
UniRef50_Q2UHM0 Cluster: Predicted protein; n=1; Aspergillus ory... 47 0.001
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 46 0.002
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 46 0.002
UniRef50_Q8DHB7 Cluster: Tlr2042 protein; n=16; Cyanobacteria|Re... 46 0.002
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 46 0.002
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 46 0.002
UniRef50_A7CR51 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 46 0.002
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 46 0.002
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 46 0.002
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 46 0.002
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 46 0.002
UniRef50_A0RX58 Cluster: Oxidoreductase; n=1; Cenarchaeum symbio... 46 0.002
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 46 0.002
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 46 0.002
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 46 0.002
UniRef50_Q397L1 Cluster: Aldo/keto reductase; n=33; Bacteria|Rep... 46 0.002
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 46 0.002
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 46 0.002
UniRef50_Q20127 Cluster: Mechanosensory abnormality protein 14; ... 46 0.002
UniRef50_Q8X1V7 Cluster: Arylalcohol dehydrogenase; n=2; Dikarya... 46 0.002
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 46 0.002
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 46 0.003
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 46 0.003
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 46 0.003
UniRef50_A4BF67 Cluster: Putative oxidoreductase; n=1; Reinekea ... 46 0.003
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 46 0.003
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 46 0.003
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.003
UniRef50_A3DM42 Cluster: Aldo/keto reductase; n=1; Staphylotherm... 46 0.003
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 46 0.003
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 45 0.004
UniRef50_Q02C17 Cluster: Aldo/keto reductase precursor; n=1; Sol... 45 0.004
UniRef50_A5ZND2 Cluster: Putative uncharacterized protein; n=1; ... 45 0.004
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 45 0.004
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 45 0.004
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 45 0.004
UniRef50_A0L9G8 Cluster: Aldo/keto reductase precursor; n=1; Mag... 45 0.004
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 45 0.004
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 45 0.004
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 45 0.004
UniRef50_Q6Q875 Cluster: SirO; n=1; Leptosphaeria maculans|Rep: ... 45 0.004
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 45 0.004
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 45 0.006
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 45 0.006
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 45 0.006
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 45 0.006
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 45 0.006
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 45 0.006
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 45 0.006
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 45 0.006
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 45 0.006
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 45 0.006
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 44 0.008
UniRef50_Q15XR1 Cluster: Aldo/keto reductase; n=1; Pseudoalterom... 44 0.008
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 44 0.008
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 44 0.010
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 44 0.010
UniRef50_Q47Q46 Cluster: Putative oxidoreductase; n=1; Thermobif... 44 0.010
UniRef50_Q2P313 Cluster: Voltage-gated potassium channel beta su... 44 0.010
UniRef50_A7CYG2 Cluster: Oxidoreductase domain protein; n=2; Opi... 44 0.010
UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.010
UniRef50_A3UGV7 Cluster: Oxidoreductase; n=1; Oceanicaulis alexa... 44 0.010
UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re... 44 0.010
UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 44 0.010
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 44 0.010
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.010
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 44 0.010
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 44 0.010
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 44 0.013
UniRef50_Q0IRD6 Cluster: Os11g0645200 protein; n=6; Oryza sativa... 44 0.013
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 44 0.013
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.013
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 44 0.013
UniRef50_Q4PB30 Cluster: Putative uncharacterized protein; n=1; ... 44 0.013
UniRef50_Q0UIH5 Cluster: Putative uncharacterized protein; n=1; ... 44 0.013
UniRef50_Q9C4S6 Cluster: Stress inducible protein; n=1; Halofera... 44 0.013
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 43 0.018
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 43 0.018
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 43 0.018
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 43 0.018
UniRef50_Q28U95 Cluster: Aldo/keto reductase; n=6; Alphaproteoba... 43 0.018
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 43 0.018
UniRef50_A1VNV6 Cluster: Aldo/keto reductase precursor; n=7; Pro... 43 0.018
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 43 0.018
UniRef50_A2XRY8 Cluster: Putative uncharacterized protein; n=2; ... 43 0.018
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 43 0.018
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 43 0.018
UniRef50_Q5KB03 Cluster: Expressed protein; n=1; Filobasidiella ... 43 0.018
UniRef50_Q0CCE6 Cluster: Predicted protein; n=1; Aspergillus ter... 43 0.018
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 43 0.018
UniRef50_A1C8R6 Cluster: Aldo-keto reductase (YakC), putative; n... 43 0.018
UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 43 0.023
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 43 0.023
UniRef50_Q5H3V6 Cluster: Rhizopine catabolism protein mocA; n=2;... 43 0.023
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 43 0.023
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 43 0.023
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 43 0.023
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 43 0.023
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 43 0.023
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 43 0.023
UniRef50_Q2UTA2 Cluster: Predicted oxidoreductase; n=9; Eurotiom... 43 0.023
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 43 0.023
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.031
>UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:
ENSANGP00000006086 - Anopheles gambiae str. PEST
Length = 421
Score = 345 bits (847), Expect = 2e-93
Identities = 170/273 (62%), Positives = 209/273 (76%), Gaps = 27/273 (9%)
Query: 36 DSASVDSNPMPTIYRCRAPIASLDCMDDFSANSQQMLDQAGEVTVTRHMSTYMGNHTAMP 95
D+ S DSNP+ TIYRCRAPIASLDCM++FS ++ L + + + +T
Sbjct: 21 DNISEDSNPV-TIYRCRAPIASLDCMEEFSRSTS--LGSNPAIQIRSNATT--------- 68
Query: 96 SAVTPGLRYKNLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINLFDLSEAH 151
TPGLRYKNLGKSGLRV N+GLG W + +SEE E ++ A+++GINLFDLSEAH
Sbjct: 69 ---TPGLRYKNLGKSGLRVSNVGLGTWPIFSPGVSEEQAEAILRLAVDSGINLFDLSEAH 125
Query: 152 CAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
G LG+I++K +RTS +ITTKIYWSTK S+ERGLSRKH+IESV+ASL R
Sbjct: 126 --SGRQGLGKIIQKAGWKRTSFVITTKIYWSTK------SEERGLSRKHIIESVQASLQR 177
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
LQ+ YIDV+L+HK D +CPMEE+VR MNYVI++GW MYWGTARWSP EIM+AYTNCRQFN
Sbjct: 178 LQLPYIDVILVHKADSMCPMEEIVRAMNYVISQGWSMYWGTARWSPVEIMEAYTNCRQFN 237
Query: 272 CITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
C+TPIVEQ+EYHMFCREK ELY+PE+Y+KIGVG
Sbjct: 238 CVTPIVEQSEYHMFCREKAELYLPEMYNKIGVG 270
Score = 83.8 bits (198), Expect = 1e-14
Identities = 45/140 (32%), Positives = 74/140 (52%), Gaps = 2/140 (1%)
Query: 355 MVWSAITTGKGLGREEITGLFAKSRFNRKYSTFSWCEEDLAVPEMRSSGSKEQVTG--EE 412
M W ++ G + K K ++SW E+++ S ++ + +E
Sbjct: 272 MAWGPLSMYLGDAQNGEKLWIPKGSLKSKSQSYSWIEDEVNKEVSERSATRPHCSDLQDE 331
Query: 413 PRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
R DK RD++NLA L C+ QL++AW LK+E V CLLLGATS EQ +++ ALQ+
Sbjct: 332 ARRLYDKARDISNLAEKLGCNAVQLSIAWSLKHEPVQCLLLGATSPEQLHQSLQALQLLP 391
Query: 473 KKIFKVCVKSFKLLQQSPLR 492
+ V ++ ++L+ P+R
Sbjct: 392 RLSTGVMLEIERILENKPVR 411
>UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4;
Sophophora|Rep: CG32688-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 547
Score = 330 bits (811), Expect = 5e-89
Identities = 164/277 (59%), Positives = 209/277 (75%), Gaps = 37/277 (13%)
Query: 36 DSASVDSNPMPTIYRCRAPIASLDCMDDFSANSQQMLDQAGEVTVTRHMSTYMGNHTAMP 95
D+ S +SNP+ TIYRCRAPIASLDCM++FS S +G++ A+P
Sbjct: 152 DNTSDESNPV-TIYRCRAPIASLDCMEEFS------------------RSISLGSNPALP 192
Query: 96 ----SAVTPGLRYKNLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINLFDL 147
S TPGLRYKNLGKSGLR+ N+GLG W + +S++ E ++ A+E+GINLFD+
Sbjct: 193 LRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDI 252
Query: 148 SEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKA 207
SEAH E E+G+IL++ +RT+ +ITTK+YWSTK S+ERGLSRKH+IE V+A
Sbjct: 253 SEAH---SETEIGKILQRAGWKRTAYVITTKVYWSTK------SEERGLSRKHIIECVRA 303
Query: 208 SLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNC 267
SL RLQ++YID+V++HK DP+CPM E+VR M+YVI +GW MYWGTARWS EIM+AYTNC
Sbjct: 304 SLQRLQLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNC 362
Query: 268 RQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
RQFNCITPIVEQ+EYHMFCREK ELY+PE+Y+KIGVG
Sbjct: 363 RQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVG 399
Score = 87.0 bits (206), Expect = 1e-15
Identities = 45/113 (39%), Positives = 72/113 (63%), Gaps = 5/113 (4%)
Query: 383 KYSTFSWCEEDL---AVPEMRSSGSKEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAV 439
K +FSW E+++ A + S K+++ +E R + D+LRDLA LA L CS +QL++
Sbjct: 427 KTKSFSWTEDEINRNAALSPQGSWGKDRI--DEGRRHCDRLRDLAALAEKLGCSPTQLSI 484
Query: 440 AWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKVCVKSFKLLQQSPLR 492
AW LK+E V CLLLGATS EQ +++ +LQ+ + V ++ ++L+ P+R
Sbjct: 485 AWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVR 537
>UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit
beta-3 (K(+) channel subunit beta-3); n=69;
Euteleostomi|Rep: Voltage-gated potassium channel
subunit beta-3 (K(+) channel subunit beta-3) - Homo
sapiens (Human)
Length = 404
Score = 248 bits (606), Expect = 4e-64
Identities = 115/211 (54%), Positives = 154/211 (72%), Gaps = 10/211 (4%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTALENGINLFDLSEAHCA-KG 155
G++Y+NLGKSGLRV +GLG W + +S+E+ EDV+ A E+G+NLFD +E + A K
Sbjct: 77 GMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKA 136
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E LG ILK + RR+S +ITTKI+W + T ERGLSRKH+IE ++ SL RLQ+
Sbjct: 137 ERTLGNILKSKGWRRSSYVITTKIFWGGQAET-----ERGLSRKHIIEGLRGSLERLQLG 191
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+V ++ DP CPMEE+VR M YVIN+G +YWGT+RW +EIM+AY+ RQFN I P
Sbjct: 192 YVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPP 251
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ EQ E+H+F REK E+ +PELYHKIGVG +
Sbjct: 252 VCEQAEHHLFQREKVEMQLPELYHKIGVGSV 282
Score = 65.3 bits (152), Expect = 4e-09
Identities = 29/66 (43%), Positives = 47/66 (71%)
Query: 405 KEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKEN 464
K++V E+ + K+ DL +A+ L C+++QLA+AWCL++E V+ +LLG +S EQ E+
Sbjct: 315 KDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEH 374
Query: 465 IHALQV 470
+ ALQV
Sbjct: 375 LGALQV 380
>UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit
beta-1 (K(+) channel subunit beta-1); n=70;
Euteleostomi|Rep: Voltage-gated potassium channel
subunit beta-1 (K(+) channel subunit beta-1) - Homo
sapiens (Human)
Length = 419
Score = 241 bits (589), Expect = 4e-62
Identities = 117/211 (55%), Positives = 151/211 (71%), Gaps = 10/211 (4%)
Query: 99 TPGLRYKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDLSEAHCA- 153
T G+ ++NLGKSGLRV +GLG W +S+E E ++ A E+G+NLFD +E + A
Sbjct: 86 TTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAG 145
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
K E LG I+KK+ RR+S++ITTK+YW K T ERGLSRKH+IE +K SL RLQ
Sbjct: 146 KAEVILGSIIKKKGWRRSSLVITTKLYWGGKAET-----ERGLSRKHIIEGLKGSLQRLQ 200
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+EY+DVV ++ D PMEE+VR M +VIN+G MYWGT+RWS EIM+AY+ RQFN I
Sbjct: 201 LEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMI 260
Query: 274 TPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
P+ EQ EYH+F REK E+ +PELYHKIGVG
Sbjct: 261 PPVCEQAEYHLFQREKVEVQLPELYHKIGVG 291
Score = 77.0 bits (181), Expect = 1e-12
Identities = 37/86 (43%), Positives = 56/86 (65%)
Query: 405 KEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKEN 464
KE++ EE R +KL+DL+ +A L C++ QLAVAWCL+NE V+ +LLG+++ EQ EN
Sbjct: 326 KERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIEN 385
Query: 465 IHALQVYIKKIFKVCVKSFKLLQQSP 490
+ A+QV K V + +L+ P
Sbjct: 386 LGAIQVLPKMTSHVVNEIDNILRNKP 411
>UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 462
Score = 240 bits (587), Expect = 7e-62
Identities = 117/227 (51%), Positives = 157/227 (69%), Gaps = 18/227 (7%)
Query: 83 HMSTYMGNHTAMPSAVTPGLRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTAL 138
HM +G HT+M +Y+NLGKSGLRV +GLG W + +S+E E+++ A
Sbjct: 91 HMKEAIGRHTSM--------KYRNLGKSGLRVSCLGLGTWVTFGSQISDEMAENLMTIAY 142
Query: 139 ENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS 197
ENG+NLFD +E + + + E LG I+KK+ RR+S +ITTKIYW + T ERGLS
Sbjct: 143 ENGVNLFDTAEVYASGRAEITLGNIIKKKGWRRSSFVITTKIYWGGQAET-----ERGLS 197
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
RKH+IE ++ SL RLQ++Y+D+V ++ D PMEE+VR M +VIN+G MYWGT+RWS
Sbjct: 198 RKHIIEGLRGSLSRLQLDYVDIVFANRNDVNSPMEEIVRAMTFVINQGMAMYWGTSRWSA 257
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
EIM+AY+ RQFN I P+ EQ EYH F R+K E+ +PELYHKIGVG
Sbjct: 258 MEIMEAYSVARQFNLIPPVCEQAEYHYFQRDKVEVQLPELYHKIGVG 304
Score = 41.1 bits (92), Expect = 0.071
Identities = 20/63 (31%), Positives = 35/63 (55%)
Query: 428 NSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKVCVKSFKLLQ 487
N L S +AWCL++E V+ +LLG ++ +Q EN+ AL++ + ++ + LL
Sbjct: 392 NMLQIQGSFSFLAWCLRSEGVSSVLLGVSTTDQLLENLGALRILTQMTPQIVTEIDALLG 451
Query: 488 QSP 490
P
Sbjct: 452 NKP 454
>UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7044,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 440
Score = 202 bits (492), Expect = 2e-50
Identities = 103/221 (46%), Positives = 145/221 (65%), Gaps = 15/221 (6%)
Query: 92 TAMPSAVTPGLRYKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDL 147
+A +A+TP +NLGKSGLRV +GLG W ++++ E+++ A E+G+NLFD
Sbjct: 71 SAQFAALTPACPSRNLGKSGLRVSCLGLGTWVTFGGQVTDQVAEELLTLAYESGVNLFDT 130
Query: 148 SEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVK 206
+E + + E LG+I+KK+ RR+S++ITTK++W + ERGLSRKH+IE ++
Sbjct: 131 AEVYNGGRSEVVLGKIIKKKGWRRSSLVITTKLFWGGRAEM-----ERGLSRKHIIEGLR 185
Query: 207 ASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMN-----YVINEGWVMYWGTARWSPSEIM 261
SL RLQ++Y+DVV ++ DP P+E VIN+G MYWGT+RWS EIM
Sbjct: 186 ESLQRLQLDYVDVVFANRPDPTTPIEGRAETCTRAHDPMVINQGMAMYWGTSRWSSVEIM 245
Query: 262 DAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIG 302
+AY+ RQFN I P+ EQ EYHMF REK E+ +PEL KIG
Sbjct: 246 EAYSMARQFNQIPPVCEQAEYHMFQREKVEVQLPELALKIG 286
Score = 70.5 bits (165), Expect = 1e-10
Identities = 36/86 (41%), Positives = 52/86 (60%)
Query: 405 KEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKEN 464
K+++ EE R KL +L LA L C+++QLA+AWCL+N V+ +LLGA+ EQ EN
Sbjct: 347 KDRLLSEEGRRQQRKLGELQALAQRLGCTLAQLAIAWCLRNPGVSAVLLGASGTEQLAEN 406
Query: 465 IHALQVYIKKIFKVCVKSFKLLQQSP 490
+ A+QV K V + +LL P
Sbjct: 407 LRAVQVLPKLSPSVLSEVEQLLGNKP 432
>UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular
organisms|Rep: K+ channel protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 328
Score = 173 bits (422), Expect = 7e-42
Identities = 84/209 (40%), Positives = 128/209 (61%), Gaps = 12/209 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
++YKNLGKSGL+V + G W L + + ++ ++G+N FD +E + A G A
Sbjct: 1 MQYKNLGKSGLKVSTLSFGAWVTFGNQLDVKEAKSILQCCRDHGVNFFDNAEVY-ANGRA 59
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G+ +++ RR+ I+I+TKI+W +++GLSRKH++E KASL RL ++
Sbjct: 60 EEIMGQAIRELGWRRSDIVISTKIFWG-----GPGPNDKGLSRKHIVEGTKASLKRLDMD 114
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+DV+ H+ D P+EE VR MNYVI++GW YWG + WS +I +A+ + + + P
Sbjct: 115 YVDVLYCHRPDASTPIEEAVRAMNYVIDKGWAFYWGISEWSAQQITEAWGAADRLDLVGP 174
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
IVEQ EY+MF R K E LY G+G
Sbjct: 175 IVEQPEYNMFARHKVETEFLPLYTNHGIG 203
Score = 48.0 bits (109), Expect = 6e-04
Identities = 25/74 (33%), Positives = 41/74 (55%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKV 478
K+ L +A L +++QLA+AWC N +V+ ++ GAT Q +EN+ A+ V V
Sbjct: 250 KVSGLKPIAGELGVTLAQLAIAWCASNPNVSSVITGATRGSQIQENMKAVDVIPLLTPIV 309
Query: 479 CVKSFKLLQQSPLR 492
K +++Q P R
Sbjct: 310 LDKIEQVIQSKPKR 323
>UniRef50_Q40648 Cluster: Probable voltage-gated potassium channel
subunit beta (K(+) channel subunit beta); n=5;
Eukaryota|Rep: Probable voltage-gated potassium channel
subunit beta (K(+) channel subunit beta) - Oryza sativa
subsp. japonica (Rice)
Length = 328
Score = 163 bits (397), Expect = 8e-39
Identities = 78/209 (37%), Positives = 126/209 (60%), Gaps = 12/209 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
++YKNLG+SGLRV + G W L + + ++ + G+N FD +E + A G A
Sbjct: 1 MQYKNLGRSGLRVSQLSYGAWVTFGNQLDVKEAKALLQACRDAGVNFFDNAEVY-ANGRA 59
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G+ ++ RR+ ++++TK++W +++GLSRKH++E ++ SL RL ++
Sbjct: 60 EEIMGQAMRDLGWRRSDVVVSTKLFWG-----GQGPNDKGLSRKHIVEGLRGSLKRLDMD 114
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+DVV H+ D P+EE VR MN+VI+ G YWGT+ WS +I +A++ + + + P
Sbjct: 115 YVDVVYCHRPDATTPVEETVRAMNWVIDHGMAFYWGTSEWSAQQITEAWSVANRLDLVGP 174
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
IVEQ EY++F R K E LY G+G
Sbjct: 175 IVEQPEYNLFSRHKVESEFLPLYSTYGLG 203
Score = 51.2 bits (117), Expect = 7e-05
Identities = 27/74 (36%), Positives = 41/74 (55%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKV 478
K+ L +A+ L S++QLA+AWC N +V+ ++ GAT Q EN+ AL V +V
Sbjct: 250 KVNGLKPIASELGVSLAQLAIAWCASNPNVSSVITGATKENQIVENMKALDVIPLLTPEV 309
Query: 479 CVKSFKLLQQSPLR 492
K ++Q P R
Sbjct: 310 VDKIEAVVQSKPKR 323
>UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: Aldo/keto reductase -
Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 157 bits (380), Expect = 9e-37
Identities = 78/208 (37%), Positives = 122/208 (58%), Gaps = 12/208 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTALENGINLFDLSEAHC-AKGE 156
+ Y+ +GK GL++ + LG W L S + VV A+ENGIN D +EA+ E
Sbjct: 1 MEYRKVGKWGLKISEVSLGSWLTFGNQLDLNSTKQVVRYAVENGINFIDTAEAYANGIAE 60
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
A LG +LK+ RR ++I+TKI+W + +++GLSRKH++E SL RLQ++Y
Sbjct: 61 AMLGMVLKE--YRREDLVISTKIFWG-----GDGPNQKGLSRKHLLEGTWNSLKRLQLDY 113
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D++ H+ DP PMEE+V M+ ++ G YWGT+ WS EI A + N + P+
Sbjct: 114 VDILYCHRPDPEVPMEEVVYTMDQILKSGLAFYWGTSEWSAEEIEQACKVAEKMNAMPPV 173
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVG 304
VEQ +Y++ +++ E +Y K G+G
Sbjct: 174 VEQPQYNLIFKKRVEEEYAPIYEKYGIG 201
Score = 57.6 bits (133), Expect = 8e-07
Identities = 23/52 (44%), Positives = 39/52 (75%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
KL+ + +A L +M+QL++AWCL+N V+ ++LG +S++Q KENI A++V
Sbjct: 250 KLKRIKEIAEGLGVTMAQLSIAWCLRNPHVSSVILGVSSLDQLKENIKAVEV 301
>UniRef50_Q5D8T1 Cluster: SJCHGC06048 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06048 protein - Schistosoma
japonicum (Blood fluke)
Length = 237
Score = 155 bits (376), Expect = 3e-36
Identities = 89/222 (40%), Positives = 135/222 (60%), Gaps = 15/222 (6%)
Query: 104 YKNLGKSGLRVPNIGLG----LWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE- 158
Y+NLG +GLRV + LG + +E E ++ A +GIN+F+ EA+ + GEAE
Sbjct: 17 YRNLGSTGLRVSVLSLGTDVTFGNQIPDEMAEKIITMAYTSGINVFETGEAY-SNGEAER 75
Query: 159 -LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
LGRIL +N RR+S I+ ++ S + T E+GLSRKH+ E +++SL RLQ+EY+
Sbjct: 76 TLGRILTAKNWRRSSYIVCCRLSKSGEAET-----EKGLSRKHLFEGLRSSLERLQLEYV 130
Query: 218 DVVLLHKV-DPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
D+V++ + D P+EE+VR + I+ GW YWGT+ W P EIM A T RQFN I P
Sbjct: 131 DIVIVTRQRDSPIPVEEVVRTCTHFIHLGWTFYWGTSEWLPCEIMQAQTVARQFNLIPPS 190
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVGKIYI-LFFIQLNYR 317
V+Q E ++ + + M E+ K+ V ++ + FF ++N R
Sbjct: 191 VDQNELNLLNKSHLQ-NMREICLKLNVSRLSVSRFFREMNNR 231
>UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=16; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 365
Score = 153 bits (372), Expect = 8e-36
Identities = 76/210 (36%), Positives = 124/210 (59%), Gaps = 7/210 (3%)
Query: 102 LRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTALENGINLFDLSEAH-CAKGE 156
+ Y+ LG +G++V IGLG + T E I +V A GIN FD +E++ +GE
Sbjct: 1 MEYRFLGNTGIKVSAIGLGNYLNGETPDKREKIIQIVKKAYSLGINFFDTAESYGYGEGE 60
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNN--RSDERGLSRKHVIESVKASLGRLQV 214
+ G K+ + R +++++KI+W+ T+ + ++ GLSRKH+IE VK SL RLQ+
Sbjct: 61 LQYGEAFKELGIPREELVVSSKIFWAVTPFTSQIQKVNQIGLSRKHIIEGVKVSLKRLQL 120
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+Y+D+V H+ D P+EE ++ N +I +G + YWGT+ WS +I +A C + N
Sbjct: 121 DYLDIVYCHRFDEDTPLEETIKAFNDLIQQGLIHYWGTSEWSCGQIFEAREICAKLNLTP 180
Query: 275 PIVEQTEYHMFCREKPELYMPELYHKIGVG 304
P+ EQ +Y+M RE+ E+ L+ K +G
Sbjct: 181 PVCEQPQYNMMVRERFEVEYGRLFDKYRMG 210
Score = 46.8 bits (106), Expect = 0.001
Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKI 475
L L +AN + C+ +QLA+AW L N V+ + AT EQ E + +L+V +KK+
Sbjct: 266 LNALGEVANKIGCTQTQLAMAWVLANRDVSTAITSATKPEQLDEIVKSLEV-VKKL 320
>UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyces
pombe Putative potassium channel subunit; n=1; Yarrowia
lipolytica|Rep: Similar to tr|O59826 Schizosaccharomyces
pombe Putative potassium channel subunit - Yarrowia
lipolytica (Candida lipolytica)
Length = 347
Score = 145 bits (352), Expect = 2e-33
Identities = 79/199 (39%), Positives = 115/199 (57%), Gaps = 12/199 (6%)
Query: 97 AVTPGLRYKNLGKSGLRVPNIGLGLWTMLSEESIED-----VVMTALENGINLFDLSEAH 151
++ P Y+ LG SGLRV ++ LG W + +ED + A ++GIN FD +E +
Sbjct: 2 SLIPKQEYRFLGPSGLRVSSLSLGSWINYGDGGVEDKKTLEIFDKAFKSGINFFDTAEVY 61
Query: 152 CAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
A GEAE +G+I+K +RT +I+TK++W N GLSRKHV+E + SL
Sbjct: 62 RA-GEAETSMGKIIKDLGWKRTEYVISTKLFWGPTKTVN----ALGLSRKHVLEGIDESL 116
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RLQ++Y+DVV H+ D P+EE+VR VIN+G YWGT+ W+ EI A +
Sbjct: 117 KRLQLDYVDVVFAHRPDRYTPIEEVVRAFTQVINDGKAFYWGTSMWTSYEIERANHAATK 176
Query: 270 FNCITPIVEQTEYHMFCRE 288
+ I PI EQ Y++ R+
Sbjct: 177 YGLIPPIAEQPVYNLLERD 195
Score = 48.4 bits (110), Expect = 5e-04
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 397 PEMRSSGSKEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGAT 456
P ++ +KE + + K+ L+ L + LA+AW LK + ++LGAT
Sbjct: 246 PMLKRLATKE-LESDSGLANAKKVAKFVELSEELGVKPANLALAWLLKQPHTSTVILGAT 304
Query: 457 SVEQFKENIHALQVYIKKIFKVCVKSFKLLQQSPLR 492
VEQ +EN+ ++ K +V K K+ P R
Sbjct: 305 RVEQLEENLQTYEILDKVTDEVLEKIEKIFDNKPAR 340
>UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel,
shaker-related subfamily, beta member; n=5;
Bacteria|Rep: Potassium voltage-gated channel,
shaker-related subfamily, beta member - Bdellovibrio
bacteriovorus
Length = 318
Score = 142 bits (345), Expect = 2e-32
Identities = 73/214 (34%), Positives = 125/214 (58%), Gaps = 14/214 (6%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGLWTMLSEE-----SIEDVVMTALENGINLFDLSEAHCAK 154
P + Y+++G+ GL++ LG WT S+ ++ A E GIN FD+++ + AK
Sbjct: 4 PNMPYRSVGRCGLKIGTYSLGGWTTFGGTVKDFTSVRSILRLAYEAGINFFDIADIY-AK 62
Query: 155 GEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
GE+E +G LK + R ++I++K++W N ++GLSRKH++ESV SL R+
Sbjct: 63 GESERIMGGALK--DFPRHELVISSKVFWPMSEDIN----DKGLSRKHILESVNKSLQRI 116
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
+Y+D+ H+ DP P+EE VR+M+ +I+ G ++YWGT+ W+ +I +A C +
Sbjct: 117 GTDYLDIYFCHRYDPETPVEETVRIMDDLIHHGKILYWGTSEWTAEQIQEAMDICDKGGY 176
Query: 273 ITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
P VEQ +Y++ R+K E + + G+G +
Sbjct: 177 YKPQVEQPQYNLLVRDKFETNVQPKAQQHGMGLV 210
Score = 54.0 bits (124), Expect = 9e-06
Identities = 24/51 (47%), Positives = 36/51 (70%)
Query: 422 DLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+L +A+ L CS +QLA+AW V+ ++LGATS+EQ +EN+ AL+V I
Sbjct: 254 ELKGIADKLECSRTQLALAWTAAQPGVSSVILGATSIEQLQENLGALKVEI 304
>UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=8;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_141, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 349
Score = 138 bits (334), Expect = 3e-31
Identities = 72/195 (36%), Positives = 109/195 (55%), Gaps = 8/195 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIED----VVMTALENGINLFDLSEAHC-AKGE 156
+ Y+ LG +GL+V I G W ++ +D ++ A E GIN FD +E + K E
Sbjct: 1 MEYRRLGATGLKVSAISYGNWVNSDDKDTQDRNTKIIQKAWELGINFFDTAEIYGDGKAE 60
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
LG LK NV+R I+I+TKIY N+ + + LSRKH+IE ++ SL RL Y
Sbjct: 61 IHLGHALKTLNVQRQDIVISTKIYGGDG---NDFPNSKYLSRKHLIEGLRNSLKRLDTPY 117
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D+V H+ D P+EE R +++I G YWGT+ W+ +I A C + + P+
Sbjct: 118 VDIVFAHRYDYQTPLEETCRAFDWIIRHGLAHYWGTSEWTAQQIHQAIGICDRLSLHKPV 177
Query: 277 VEQTEYHMFCREKPE 291
VEQ +Y+M R++ E
Sbjct: 178 VEQPQYNMMVRDRFE 192
Score = 48.8 bits (111), Expect = 4e-04
Identities = 27/74 (36%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 406 EQVTGE-EPRT-YGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKE 463
+Q+ G+ E RT ++L+ L +A L + +QL++AW LKN+ V+ + AT EQ +E
Sbjct: 243 QQILGDPEKRTKIQNQLKQLGEVAKELGVTQAQLSLAWALKNKDVSTAITSATRPEQLEE 302
Query: 464 NIHALQVYIKKIFK 477
+ ++QV +K I K
Sbjct: 303 TVKSVQV-VKLITK 315
>UniRef50_A0DXM3 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_69,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 349
Score = 138 bits (333), Expect = 4e-31
Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 4/194 (2%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIE---DVVMTALENGINLFDLSEAH-CAKGEA 157
+ Y LG +GL + I G + E E +++ T E G+N FD +E + K E
Sbjct: 1 MEYNRLGNTGLLISKISFGNMVNFAPEDEEVNTEIIKTCYEAGVNFFDTAELYENGKAEE 60
Query: 158 ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
+LGR +KK N+ R II++ KI + + N + L+RKHVIE V ASL RLQ++Y
Sbjct: 61 QLGRSIKKLNIPRERIIVSVKILANLEQGGNPINRSFTLNRKHVIEGVNASLKRLQLDYA 120
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIV 277
D+ H +D ++E+ R N VI +G YWGT+ W PS++ +A+ C + I P+V
Sbjct: 121 DIAYAHFLDQDIQVDEICRGFNQVIEDGKAFYWGTSNWKPSKVQEAFNYCDKHGLIRPVV 180
Query: 278 EQTEYHMFCREKPE 291
EQ Y+M R E
Sbjct: 181 EQCIYNMVIRNLVE 194
Score = 55.2 bits (127), Expect = 4e-06
Identities = 27/72 (37%), Positives = 47/72 (65%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKV 478
KL+ L +LA SL + +QL++AW L N+ V+ ++GA +V+Q K+++ AL++Y K ++
Sbjct: 262 KLKKLGDLAQSLGYTQTQLSIAWVLYNKDVSTAIIGAKNVQQVKDSLKALELYKKWDKEL 321
Query: 479 CVKSFKLLQQSP 490
K +LQ P
Sbjct: 322 EQKVEAILQNKP 333
>UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:
Aldo/keto reductase - Herpetosiphon aurantiacus ATCC
23779
Length = 310
Score = 136 bits (328), Expect = 2e-30
Identities = 71/209 (33%), Positives = 122/209 (58%), Gaps = 14/209 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
+ Y+ LGK+G+RV + LG W + + + A++NGIN D+++A+ A GEA
Sbjct: 1 MEYRRLGKAGMRVSAVSLGAWLTYGGSVEGDQAAQCLRAAIDNGINFIDVADAY-AYGEA 59
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G ++ R+ +R+ +++++K+YW +NN +D+ GLSRKH++ES+ SL +
Sbjct: 60 EKVVGGVI--RDYKRSDLVLSSKLYWPM---SNNVNDQ-GLSRKHIMESIDKSLRHFGTD 113
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ H+ D P+EE VR M+ ++ G ++YWGT+ W +I A + +Q+N P
Sbjct: 114 YLDIYFCHRFDANTPLEETVRAMSDLVQAGKILYWGTSVWEAEQIEQAVSIAKQYNGYLP 173
Query: 276 IVEQTEYHMFCREKPELYMPEL-YHKIGV 303
VEQ Y+M R +P H +G+
Sbjct: 174 QVEQPRYNMLDRHIEPAIIPTCEQHGLGL 202
Score = 43.2 bits (97), Expect = 0.018
Identities = 20/55 (36%), Positives = 33/55 (60%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+K+R L +A L + SQLA+AW L+ ++ ++ GAT E +NI A +V +
Sbjct: 243 NKVRQLTTIAGDLGLTTSQLALAWVLRLPQISSVITGATKPEHVLDNIKAGEVQL 297
>UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellular
organisms|Rep: Potassium channel subunit -
Schizosaccharomyces pombe (Fission yeast)
Length = 344
Score = 134 bits (323), Expect = 7e-30
Identities = 72/207 (34%), Positives = 112/207 (54%), Gaps = 9/207 (4%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEESIE-----DVVMTALENGINLFDLSEAHC-AKGEA 157
++ LG+SGL+V LG W E + + + A + GIN FD +E + E
Sbjct: 15 FRFLGRSGLKVSAFSLGGWLTYGNEGYDVEHTKNCLKQAWDLGINTFDTAEIYSNGNSET 74
Query: 158 ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
+G+ +K+ R+ +ITTK+++ N + GLSRKH+IE + ASL RL + Y+
Sbjct: 75 VMGKAIKELGWDRSEYVITTKVFFGAGTKLPNTT---GLSRKHIIEGLNASLKRLGLPYV 131
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIV 277
DV++ H+ DP PMEE+VR +I +G YWGT+ WS EI A+ ++N I P+
Sbjct: 132 DVIMAHRPDPSVPMEEVVRAFTQLIQDGKAFYWGTSEWSAFEIEHAHHIATKYNLIAPVA 191
Query: 278 EQTEYHMFCREKPELYMPELYHKIGVG 304
+Q +Y+ R+ E + L G G
Sbjct: 192 DQPQYNYLTRDHFEKDLLPLQQIYGYG 218
Score = 56.4 bits (130), Expect = 2e-06
Identities = 29/85 (34%), Positives = 50/85 (58%)
Query: 407 QVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIH 466
Q+ E +T D++R ++ +A + + SQLA+AW LKN V+ +LGA+ EQ EN+
Sbjct: 254 QLQTPEGKTQLDQVRQISKIAEQIGATPSQLALAWTLKNPYVSTTILGASKPEQIVENVK 313
Query: 467 ALQVYIKKIFKVCVKSFKLLQQSPL 491
A++ K ++ K ++L +PL
Sbjct: 314 AVEFIDKLTPEILKKIDEILNFTPL 338
>UniRef50_Q39EI1 Cluster: Aldo/keto reductase; n=12; Burkholderia
cepacia complex|Rep: Aldo/keto reductase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 323
Score = 132 bits (320), Expect = 2e-29
Identities = 69/208 (33%), Positives = 113/208 (54%), Gaps = 8/208 (3%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDLSEAHCA-KGE 156
+ Y+ LG+SGL++ + LG W + + + + A + G+N FD +E + K E
Sbjct: 1 MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSE 60
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+G+ LK + R S I++TK +W N L+RK+++ ++ SL RLQ++Y
Sbjct: 61 EIMGQALKSLDWPRVSYIVSTKFFWGLAEAPNQYHT---LNRKYLLNAIDGSLRRLQLDY 117
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D+V H+ DP P+EE V M+ +I G +YWGT+ WS EI A + + P+
Sbjct: 118 VDLVYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAACEIAERHHLHKPV 177
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVG 304
VEQ +Y++F R + E LY G+G
Sbjct: 178 VEQPQYNLFHRTRVEQEYARLYDDYGLG 205
Score = 50.0 bits (114), Expect = 2e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
D + L +A L CS +QLA+AW L N V+ ++ GA+ +EQ ++N+ AL V
Sbjct: 250 DIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRALDV 302
>UniRef50_UPI00006CB156 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 443
Score = 125 bits (301), Expect = 3e-27
Identities = 69/211 (32%), Positives = 113/211 (53%), Gaps = 10/211 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
+ YK GKSGL+V +I + + L + +V+ A GIN ++ SE +C G+
Sbjct: 74 MEYKYFGKSGLKVSSICFSAYNLNIKNLKKSEFTNVIKKAYSLGINFYETSEQYC-NGQL 132
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWST--KFHTNNRSDER-GLSRKHVIESVKASLGRL 212
+ LG + + R ++I+ I + NN+ G S K +IESVK SL RL
Sbjct: 133 DVLLGEAFQTLAIPREELVISQTIRQPEVDQIQKNNKKTSIFGHSHKQIIESVKNSLNRL 192
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
Q+ Y+D+V + D P+EE ++ N++I +G V YWGT+RW+ ++I +A C +
Sbjct: 193 QISYLDIVYCDRFDEDTPLEETIKAFNHLIKQGLVNYWGTSRWTAAQIFEARCICAKLKL 252
Query: 273 ITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
P+++Q EY+M R+ E+ L+ K V
Sbjct: 253 SPPVIQQVEYNMLFRDTFEVEYSRLFDKYKV 283
Score = 35.1 bits (77), Expect = 4.7
Identities = 12/51 (23%), Positives = 28/51 (54%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
++ ++ + L C+ SQLA+AW L N ++ + Q +E + ++++
Sbjct: 340 IKKISLITKKLECTFSQLAMAWILANRDATSVIFCTNNQNQLEEIVESIEI 390
>UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5;
Bacteria|Rep: K+ channel beta subunit - Geobacillus
kaustophilus
Length = 315
Score = 124 bits (300), Expect = 4e-27
Identities = 69/192 (35%), Positives = 113/192 (58%), Gaps = 13/192 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
++Y+ LG++GL+V I LG W + +E+ V+ A E GIN FD + + A+GEA
Sbjct: 1 MKYRKLGRTGLKVSEISLGSWLTYGNSVEKETAIRVIDKAYELGINSFDTANVY-ARGEA 59
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G L+K R S +I TK++W + ++RGLSRKHV E + ASL RLQ++
Sbjct: 60 EKIVGEALRK--YPRESYVIATKVFWPM----GDGPNDRGLSRKHVFEQLHASLKRLQLD 113
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ H+ D P+EE +R ++ ++ +G V+Y G + W+ +I +A ++
Sbjct: 114 YVDIYYCHRYDKETPVEETLRTIDDLVRQGKVLYVGVSEWTAQQIQEALGVADRYLLDRI 173
Query: 276 IVEQTEYHMFCR 287
+V Q +Y+MF R
Sbjct: 174 VVNQPQYNMFHR 185
Score = 46.0 bits (104), Expect = 0.002
Identities = 21/56 (37%), Positives = 35/56 (62%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
K+ L +A L ++SQLA+AW L+ +V L+GA+ EQ +EN+ A+ V + +
Sbjct: 249 KVEQLEKVAAELGITLSQLALAWVLRQPNVASALIGASRPEQVEENVKAVDVVLSE 304
>UniRef50_Q9PGD5 Cluster: Voltage-gated potassium channel beta
subunit; n=33; Bacteria|Rep: Voltage-gated potassium
channel beta subunit - Xylella fastidiosa
Length = 387
Score = 122 bits (294), Expect = 2e-26
Identities = 69/209 (33%), Positives = 117/209 (55%), Gaps = 10/209 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIED----VVMTALENGINLFDLSEAHCAKGEA 157
+ Y+ LG +GL++ + G W + D +V A ++G+N FD +E + A+G A
Sbjct: 67 MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAENY-AQGRA 125
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E LG ++ + R +++K+++ R + GLSRKHV ++ A+L RL+V+
Sbjct: 126 EQVLGDVIADLRLPRDGYCVSSKVFFGPV--KEPRPTQCGLSRKHVHDACHAALKRLRVD 183
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ H+ D P+EE VR M +I +G V+YWGT+ WS ++I +A + + P
Sbjct: 184 YLDLFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAAQIAEAIAIASREHLERP 243
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
VEQ +Y++ RE+ E LY + G+G
Sbjct: 244 WVEQPQYNLLHRERVEREYVSLYAQ-GLG 271
Score = 52.4 bits (120), Expect = 3e-05
Identities = 24/50 (48%), Positives = 34/50 (68%)
Query: 421 RDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
R + +A L +QLA+AWCL+N V+ ++LGA+ V Q KEN+ ALQV
Sbjct: 321 RRFSEVAADLGQPPAQLAIAWCLRNPHVSTVILGASRVAQLKENLRALQV 370
>UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep:
Aldo/keto reductase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 335
Score = 109 bits (263), Expect = 1e-22
Identities = 67/210 (31%), Positives = 107/210 (50%), Gaps = 12/210 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLGLW----TMLSEESIEDVVMTALENGINLFDLSEAHC-AKGE 156
++ + LG SGLR+ I G W + + EE+ V AL+ GI FD ++ + E
Sbjct: 1 MQTRTLGSSGLRISEIAYGNWLTHGSQVEEEAATACVRQALDEGITTFDTADVYANTAAE 60
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+ LGR L RR + I TK+YW T +N + GLSRKH++ES+ SL RL +Y
Sbjct: 61 SVLGRALAGE--RREGLEIFTKVYWPTGPGGHN---DHGLSRKHIMESIDGSLRRLGTDY 115
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D+ H+ D P+EE + V+ +G +Y G + W +I A+ R+ I +
Sbjct: 116 VDLYQAHRYDDETPLEETMEAFADVVRQGKALYIGVSEWRAEQIRAAHELARELR-IPLV 174
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVGKI 306
Q +Y M R +P ++G+G++
Sbjct: 175 SNQPQYSMLWRVIEAEVVPTCV-ELGIGQV 203
Score = 43.6 bits (98), Expect = 0.013
Identities = 20/53 (37%), Positives = 35/53 (66%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
++++ L +A SM+QLAVAW L+N++V+ ++GA+ EQ +N+ A V
Sbjct: 249 ERVQLLEPIAAEAGLSMAQLAVAWVLQNDNVSAAIIGASRPEQVTDNVAAAGV 301
>UniRef50_Q4TBS9 Cluster: Chromosome undetermined SCAF7094, whole
genome shotgun sequence; n=3; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7094,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 474
Score = 108 bits (260), Expect = 3e-22
Identities = 68/165 (41%), Positives = 98/165 (59%), Gaps = 30/165 (18%)
Query: 89 GNHTAMPSAVTPGLRYKNLGKSGLRVPNIGLGLWT----MLSEE---------------S 129
G + ++PS G+ +NLGKSGLRV +GLG W +S+E
Sbjct: 220 GENFSLPS----GIFQRNLGKSGLRVSCLGLGTWVTFGGQISDERHGGCSELASVCDCCQ 275
Query: 130 IEDVVMT-ALENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHT 187
+ + +MT A E G+NLFD +E + + E LG I+KK+ RR+S++ITTK+YW K T
Sbjct: 276 VAEQLMTIAYEGGVNLFDTAEVYAGGRAEVILGSIIKKKCWRRSSLVITTKLYWGGKAET 335
Query: 188 NNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPME 232
ERGLSRKH+IE +K SL R+Q+EY+DVV ++ D P++
Sbjct: 336 -----ERGLSRKHIIEGLKGSLQRMQLEYVDVVFANRPDSNTPID 375
>UniRef50_Q4RV93 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14992, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 343
Score = 107 bits (256), Expect = 1e-21
Identities = 45/75 (60%), Positives = 57/75 (76%)
Query: 232 EELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPE 291
+++VR M +VIN+G MYWGT+RWS EIM+AY+ RQFN I P+ EQ EYH F R+K E
Sbjct: 125 QKIVRAMTHVINQGMSMYWGTSRWSAMEIMEAYSVARQFNLIPPVCEQAEYHFFQRDKVE 184
Query: 292 LYMPELYHKIGVGKI 306
+PELYHKIGVG +
Sbjct: 185 TQLPELYHKIGVGVV 199
Score = 72.1 bits (169), Expect = 3e-11
Identities = 34/64 (53%), Positives = 46/64 (71%), Gaps = 5/64 (7%)
Query: 169 RRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPV 228
RR+S++ITTK+YW K T ERGL+RKH+IE +K SL R+Q+EY+DVV ++ D
Sbjct: 1 RRSSLVITTKLYWGGKAET-----ERGLNRKHIIEGLKGSLQRMQLEYVDVVFANRPDSN 55
Query: 229 CPME 232
PME
Sbjct: 56 TPME 59
Score = 70.5 bits (165), Expect = 1e-10
Identities = 29/68 (42%), Positives = 49/68 (72%)
Query: 405 KEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKEN 464
+E++ E+ R KL++LA++A L C++ QLA+AWCL+NE V+ +LLG+++ Q EN
Sbjct: 232 REKIMSEDGRKQQAKLKELAHIAEKLGCTLPQLAIAWCLRNEGVSSVLLGSSNPSQLTEN 291
Query: 465 IHALQVYI 472
+ A+QV +
Sbjct: 292 LGAIQVNV 299
>UniRef50_Q5K978 Cluster: Aryl-alcohol dehydrogenase, putative; n=3;
Filobasidiella neoformans|Rep: Aryl-alcohol
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 357
Score = 106 bits (255), Expect = 1e-21
Identities = 74/229 (32%), Positives = 114/229 (49%), Gaps = 27/229 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGL----------WTMLSEESIEDVVMTALENGINLFDLSEAH 151
+RY LGKSGL+V I LG W + +E IE + A NGIN FD ++ +
Sbjct: 7 MRYVRLGKSGLKVSKIILGCMSYGDPEWHEWVLREKEGIEH-IKYAYANGINTFDTADIY 65
Query: 152 -CAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHT------------NNRSDERGLSR 198
C E LG+ +++ + R ++I TK++ + + +++ GLSR
Sbjct: 66 SCGASEEILGKAIREIDCSREDVVILTKLFMPVTHDSRAPPPPFPDLDKSGYTNQYGLSR 125
Query: 199 KHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG-TARWSP 257
KH+ +V+ASL RL VEYIDV+ H+ D P+EE ++ ++ V+ +GWV Y G ++ W+
Sbjct: 126 KHIFAAVQASLKRLNVEYIDVLQCHRFDYNTPIEETMQALHDVVQKGWVRYIGMSSCWAY 185
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
A N N +TP V +H + E M GVG I
Sbjct: 186 Q--FHAMQNYAINNRLTPFVSMQNFHNAAYREEEREMIPTLQMFGVGCI 232
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/66 (24%), Positives = 37/66 (56%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKIFKVCVKS 482
+ +A SM+Q+A+AW L E + ++G TS+++ K+ + A+ + + + K ++
Sbjct: 279 IEQIAEKRGISMAQVALAWSLSKEYITAPIVGTTSLDKLKDLLAAVNLELTEEEKKAIEE 338
Query: 483 FKLLQQ 488
+ Q+
Sbjct: 339 HYVPQE 344
>UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Aldo/keto reductase -
Herpetosiphon aurantiacus ATCC 23779
Length = 325
Score = 105 bits (252), Expect = 3e-21
Identities = 67/217 (30%), Positives = 115/217 (52%), Gaps = 17/217 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGL----WTMLSEESIEDVVMTALENGINLFDLSE-------- 149
+RY+ LG++GL+V + LG W++ ES ++ AL+ GIN FD ++
Sbjct: 1 MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFA-IMSQALDAGINFFDTADVYSRWDPR 59
Query: 150 AHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
++ K E +GR L + RR +++ TK+ + ++ +++GLSRKH+I +V ASL
Sbjct: 60 SYAGKTEEIIGRWLAEEPSRRDKVVLATKV----RGQMGDQPNDQGLSRKHIIAAVDASL 115
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RLQ +YID+ H D P+EE +R ++ ++ G V Y G + + ++++A +
Sbjct: 116 RRLQTDYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSNYRAWQLIEALWTSDK 175
Query: 270 FNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
N Q YH+ R + E + + K GVG I
Sbjct: 176 LNLARYDSLQPHYHLLNRAEFERELQPVCAKYGVGVI 212
>UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep:
Aldo/keto reductase - Shewanella sp. (strain W3-18-1)
Length = 360
Score = 105 bits (251), Expect = 4e-21
Identities = 71/218 (32%), Positives = 111/218 (50%), Gaps = 22/218 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLG---------LWTM---LSEESIEDVVMTALENGINLFDLSE 149
+RYK LG SGL V + LG +W + L +E +++V AL+ GIN D +
Sbjct: 14 IRYKALGNSGLMVSELCLGTMTFGGDEDIWGLIGQLRQEQADELVRIALQAGINFIDTAN 73
Query: 150 AHCAKGEAEL--GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKA 207
+ G +EL G+ LK VRR +++ TK+ N RG SR H++ KA
Sbjct: 74 IY-GLGASELIVGQSLKNLGVRREDVVLATKVLGPMGEGPN----ARGASRGHIMNECKA 128
Query: 208 SLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNC 267
SL RLQ +YID+ +H DP P+EE + +N ++ +G+V Y G + W+ ++M A
Sbjct: 129 SLSRLQTDYIDLYQIHGFDPATPIEETLEALNTLVQQGYVRYVGLSNWAAWQVMKA-IGI 187
Query: 268 RQFNCITPIVE-QTEYHMFCREKPELYMPEL-YHKIGV 303
Q + P+ Q Y + R+ +P L K+G+
Sbjct: 188 SQARNLCPVTSLQAYYTLVGRDLEREVIPMLSSEKVGL 225
Score = 41.9 bits (94), Expect = 0.041
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 433 SMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
S++Q+A+AW L ESV+ +++GA EQ K NI A Q+
Sbjct: 286 SVAQIALAWLLHQESVSSIIVGAKRPEQLKANIRAAQI 323
>UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia
xenovorans LB400|Rep: Aldo/keto reductase - Burkholderia
xenovorans (strain LB400)
Length = 340
Score = 103 bits (246), Expect = 2e-20
Identities = 69/204 (33%), Positives = 106/204 (51%), Gaps = 15/204 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGL-------WT--MLSEESIEDVVMTALENGINLFDLSEAHC 152
++YK LGKSGLRV + LG+ W +L + + VM ALE+GIN FD ++ +
Sbjct: 1 MQYKQLGKSGLRVSGLCLGMMSYGSSKWAPWVLDKSAGAAFVMQALEHGINFFDTADFYS 60
Query: 153 -AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
E LG + RR +I+TK+ TN R GLSRKH+ ESV ASL R
Sbjct: 61 YGASEEVLGEAINSVG-RRHETVISTKVGLPMDQSTNGR----GLSRKHIHESVNASLRR 115
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
L+ +YID+ LH D P+EE V +N ++ G ++Y+G + + ++ A+ +
Sbjct: 116 LKTDYIDLYTLHVPDSATPIEETVDALNDLVGAGKILYYGASNYMTWQLAHAHYTALSRS 175
Query: 272 CITPIVEQTEYHMFCREKPELYMP 295
Q +Y++ RE+ +P
Sbjct: 176 GRGFTSMQLQYNLLYREEERDMLP 199
>UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium
thermophilum|Rep: Oxidoreductase - Symbiobacterium
thermophilum
Length = 316
Score = 101 bits (242), Expect = 5e-20
Identities = 69/210 (32%), Positives = 114/210 (54%), Gaps = 14/210 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLG---LWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
+ Y+NLG+SGL+V + LG T E + +V AL+ GINL D ++ + +GE+E
Sbjct: 1 MEYRNLGRSGLKVSKMALGTNAFGTRTDEATAIRIVHAALDAGINLIDTADMY-GQGESE 59
Query: 159 --LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+G LK R R+ ++ TK ++ T + ++RG SRKH++++V ASL RLQ +Y
Sbjct: 60 RMIGLALKDR---RSRAVLATKCWYPT----GDGPNDRGASRKHIMDAVDASLRRLQTDY 112
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ +H+ D P+EE +R + ++ G V Y G + ++ +I+ A + I
Sbjct: 113 IDLYQIHRWDGDTPIEETMRALEDLVRAGKVRYIGCSNFAAWQIVMANAVADRHGWSRFI 172
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVGKI 306
Q EY R+ + +P GVG+I
Sbjct: 173 SNQPEYSPVSRQIEQEVIPACLAD-GVGQI 201
Score = 36.7 bits (81), Expect = 1.5
Identities = 15/55 (27%), Positives = 30/55 (54%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
D + + ++A +++QL +AW + V ++GA+ EQ EN+ A +V +
Sbjct: 245 DLVEAMEHVAREAGLTLTQLTLAWVMARPGVTAAIVGASRPEQVAENVSACEVQL 299
>UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10;
Proteobacteria|Rep: Aldo/keto reductase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 340
Score = 99.1 bits (236), Expect = 3e-19
Identities = 70/216 (32%), Positives = 110/216 (50%), Gaps = 22/216 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---------LSEESIEDVVMTALENGINLFDLSEAHC 152
+ Y LG+SGL+V + LG M E E +V AL+ G+N DL++ +
Sbjct: 1 MEYVRLGQSGLKVSRLCLGTMNMGTPEWKPWIFDEAQSEPIVRRALDAGVNFIDLADFYS 60
Query: 153 AK-GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
GE +GRILK RN RR +++TTK+ + + N G SRKHV++ + SL R
Sbjct: 61 TGVGEEVVGRILK-RNARREELVVTTKVGYDMGSYPN----AGGHSRKHVLDGIDGSLKR 115
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA---RWSPSEIMDAYTNCR 268
L ++YID+ +LH D P+EE + ++ ++ G Y G + W ++IM A C
Sbjct: 116 LGMDYIDIFMLHFFDVNTPVEETMSTLHDIVRAGKARYIGVSTMYTWQFAKIMQA---CE 172
Query: 269 QFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ PI Q + ++ RE+ +P + GVG
Sbjct: 173 RNGWDKPINMQLQLNLAYREEEREMVPYCIDQ-GVG 207
>UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia
ambifaria AMMD|Rep: Aldo/keto reductase - Burkholderia
cepacia (strain ATCC 53795 / AMMD)
Length = 364
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/214 (29%), Positives = 109/214 (50%), Gaps = 18/214 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT---------MLSEESIEDVVMTALENGINLFDLSEAHC 152
+ Y LG SGL+V + LG T +++EE+ + AL+ G+ FD ++ +
Sbjct: 1 MEYVRLGMSGLKVSKLCLGCMTYGDPSWRPWVMNEEAARPFIRAALDAGVTFFDTADIYS 60
Query: 153 AKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
A GE+E LGR L+ R ++I TK + F T + + RGLSRKH++ S+ ASL
Sbjct: 61 A-GESERILGRALRDF-ATRDDVVIATKAF----FPTGDGPNARGLSRKHLLASIDASLQ 114
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQF 270
RL +Y+D+ ++H+ DP P+EE + ++ ++ G V Y + + M +
Sbjct: 115 RLGTDYVDLYVIHRFDPDTPIEETLDTLDAIVKSGKVRYLAASSMHAWQFMIMLAFQQHH 174
Query: 271 NCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ Q++Y + CR+ +P L G+G
Sbjct: 175 GLARFVSMQSQYSLICRDDEREMLP-LCTDAGIG 207
>UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium
phytofermentans ISDg|Rep: Aldo/keto reductase -
Clostridium phytofermentans ISDg
Length = 323
Score = 98.7 bits (235), Expect = 3e-19
Identities = 64/208 (30%), Positives = 111/208 (53%), Gaps = 14/208 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
++Y+ + +GL+V + LG T SE+ +++ AL G+N D ++A+ KGE+E
Sbjct: 1 MKYRKMNATGLKVSELCLGTMTFGAQTSEKESLEIIDYALSQGVNFIDTADAY-NKGESE 59
Query: 159 --LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+G+ LK R II+ +K+ F T + + RGL+R+H+I+ ++ S+ LQ +Y
Sbjct: 60 RIVGKALKGC---REDIILASKVC----FKTGDDINARGLNRRHIIKQIEESIKSLQTDY 112
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D+ LH +D EE + M ++ G V Y G + + ++ + + N I PI
Sbjct: 113 LDIYYLHAMDGEVDFEETLDTMTTLVRSGKVRYIGISNYPAWQLSEMLWTADKRNLIPPI 172
Query: 277 VEQTEYHMFCRE-KPELYMPELYHKIGV 303
V Q Y++ RE + EL L H IG+
Sbjct: 173 VTQNMYNIITREVEHELVPCLLKHHIGM 200
Score = 41.9 bits (94), Expect = 0.041
Identities = 17/51 (33%), Positives = 32/51 (62%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
+ +R L+ +AN N S+ L++ WCL + V+ ++ G + + Q ++NI AL
Sbjct: 244 EAVRRLSEVANQHNMSLLSLSLNWCLAHSYVDSIICGVSKLSQLEQNIEAL 294
>UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep:
AGR_pAT_274p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 361
Score = 96.7 bits (230), Expect = 1e-18
Identities = 63/195 (32%), Positives = 98/195 (50%), Gaps = 18/195 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM------------LSEESIEDVVMTALENGINLFDLSE 149
++ + LG+SGL V + G T L +E + +V ALE GINLFD +
Sbjct: 24 MQMRKLGESGLFVSELCFGAMTFGGTDGLWGKVGRLDQEDADALVKAALEAGINLFDTAN 83
Query: 150 AHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKAS 208
+ + E LGR LK V R+ ++I TK+ + N+R G SR H+I +AS
Sbjct: 84 VYAHGRSEEILGRSLKNLGVSRSDVVIATKVASAMGDGPNHR----GASRGHIISECRAS 139
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCR 268
LGRL +++ID+ +H D P+EE + ++ ++ G V Y G + W+ +IM A R
Sbjct: 140 LGRLGLDHIDLYQIHAFDSATPIEETLEALDTLVRAGDVRYIGLSNWAAWQIMKAIGITR 199
Query: 269 QFNCITPIVEQTEYH 283
+ PI Y+
Sbjct: 200 A-RALAPITSLQAYY 213
Score = 40.7 bits (91), Expect = 0.094
Identities = 18/48 (37%), Positives = 30/48 (62%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
L +A S +Q+A+AW LK + V+ +++GA VEQ +ENI + +
Sbjct: 281 LKAVAEKHGSSPAQIAIAWLLKQKVVSTVIIGAKRVEQLQENIRSASI 328
>UniRef50_A1CYI6 Cluster: Oxidoreductase; n=15; cellular
organisms|Rep: Oxidoreductase - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 371
Score = 95.1 bits (226), Expect = 4e-18
Identities = 70/234 (29%), Positives = 116/234 (49%), Gaps = 27/234 (11%)
Query: 98 VTPGLRYKNLGKSGLRVPNIGLGLWTM----------LSEESIEDVVMTALENGINLFDL 147
V+ ++Y LG SGLRV I +G + L EE V+ A +G+N FD
Sbjct: 24 VSVKMKYVQLGSSGLRVSPICVGCMSYGSPEKRFDWALGEEDALPVLDHAYRSGLNFFDT 83
Query: 148 SEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTK-------FHTNNRSD------ 192
+ + + G++E LG+ +KK N RR +I+I TK++ F +N D
Sbjct: 84 ANVY-SNGDSEVILGKAIKKYNWRRENIVIATKVWAPVGRGKEYPLFMSNEERDNAGYVN 142
Query: 193 ERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGT 252
E GLSRKH+ +S++ASL RL + Y+D++ +H+ D P++E + ++ V+ G V Y G
Sbjct: 143 EYGLSRKHIFDSIEASLKRLDLPYVDLLQIHRFDDNTPVKETMEALHDVVKSGKVRYIGA 202
Query: 253 ARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ ++++ Y + N T + +H + E M K G+G I
Sbjct: 203 SSMWAHQLLE-YQYTARMNGWTEFISMQNFHNPIYREEEREMFPACAKFGMGAI 255
>UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;
Bacteria|Rep: Uncharacterized conserved protein -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 337
Score = 92.3 bits (219), Expect = 3e-17
Identities = 55/201 (27%), Positives = 111/201 (55%), Gaps = 11/201 (5%)
Query: 101 GLR-YKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMT---ALENGINLFDLSEAHCAKGE 156
GL+ Y+N G++G+++ + LG ++ ++D V A++ GIN+ D + + A+G
Sbjct: 2 GLKDYRNFGRTGVKISPLTLGCMMFGNKTELDDTVRIIDRAIDAGINIIDTANVY-ARGR 60
Query: 157 AE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
+E G LK RN +R I + +K++ H + + RG SR+H+I+ V+ SL RLQ
Sbjct: 61 SEEFTGEALK-RNGKRKDIFLASKVH--LPMHDTD-GNLRGSSRRHIIQQVEDSLRRLQT 116
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+Y+D+ +H+ +P ++E +R ++ ++ G V Y G+ ++ ++++A ++
Sbjct: 117 DYLDLYQIHRPEPTTAIDETLRALDDLVKSGKVRYIGSTTFAGWQVVEALWASKELGLNR 176
Query: 275 PIVEQTEYHMFCREKPELYMP 295
+ EQ Y++ R +P
Sbjct: 177 FVSEQPPYNLLDRRIERELLP 197
Score = 36.3 bits (80), Expect = 2.0
Identities = 16/53 (30%), Positives = 29/53 (54%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
D + L+ LA +SQLA+AW + V + G ++EQ ++ + A++V
Sbjct: 250 DVIEPLSELAAEKGVPLSQLALAWVAQQRGVTSAITGPRTLEQLEDALQAIEV 302
>UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=77;
cellular organisms|Rep: Uncharacterized oxidoreductase
yajO - Escherichia coli (strain K12)
Length = 324
Score = 91.5 bits (217), Expect = 5e-17
Identities = 66/217 (30%), Positives = 104/217 (47%), Gaps = 20/217 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-----------LSEESIEDVVMTALENGINLFDLSEA 150
++Y LGK+ LRV + LG T L EES ++ ALE GIN FD + +
Sbjct: 1 MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS 60
Query: 151 HCAKGEAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ E+ GR L+ RR +++ TK+ FH E GLSR ++ S+ SL
Sbjct: 61 YSDGSSEEIVGRALRDF-ARREDVVVATKV-----FHRVGDLPE-GLSRAQILRSIDDSL 113
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RL ++Y+D++ +H+ D P+EE + +N V+ G Y G + S+ A +Q
Sbjct: 114 RRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQ 173
Query: 270 FNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ Q Y++ RE+ +P Y + GV I
Sbjct: 174 HGWAQFVSMQDHYNLIYREEEREMLPLCYQE-GVAVI 209
>UniRef50_A5DEF4 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 339
Score = 90.2 bits (214), Expect = 1e-16
Identities = 58/212 (27%), Positives = 106/212 (50%), Gaps = 8/212 (3%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMT-ALENGINLFDLSEAHCA-KGEAE 158
GLR + + + +G + +S+E+ ++ + G+ FD ++ + A E
Sbjct: 15 GLRINHAVVGTMLLGKVGYENYNGVSDEAESIAILKQCYDAGLRTFDTADIYSAGNSERV 74
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRS----DERGLSRKHVIESVKASLGRLQV 214
+G LK+ N+ R ++I TK Y+ + +++GLSRKH++++VK S+ RL
Sbjct: 75 IGEFLKQHNIPREDVVIMTKCYFRLADRQGDSGKLQFNDKGLSRKHILDAVKDSVARLGT 134
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
YID++ +H+ DP P EE++R +N V+ G V Y G + + + +
Sbjct: 135 -YIDLLQIHRYDPDVPDEEIMRALNDVVESGQVRYLGASSMKLYQFIQLQHTAEKHGWHK 193
Query: 275 PIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ Q+ Y++ RE E + E +K GVG I
Sbjct: 194 FVSMQSMYNLIYRE-DERELNEYCNKTGVGLI 224
>UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 344
Score = 89.8 bits (213), Expect = 2e-16
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 30/211 (14%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFDLS 148
++Y NLG+SG++V + +G W + + +E+ ++ A + G+N D +
Sbjct: 8 MKYVNLGESGVKVSQVAIGTWFLPRLQEKDELGIYKVDKETTLKILKRAYDEGVNFIDTA 67
Query: 149 EA-----------HCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS 197
H E +G LK V R S++I+TK+ N GLS
Sbjct: 68 NRYHGAMAPVDLPHVGNAERIVGEFLK--TVDRESVVISTKVRGKMGDFVNGE----GLS 121
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
RKH++ +K SL RL YIDV +H DP P E +R +N ++N G V Y G + S
Sbjct: 122 RKHILWQIKESLKRLGTSYIDVYFIHWPDPDTPKLETLRTLNSLVNNGLVYYLGVSNHSA 181
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCRE 288
++M+ + N IV Q +Y+M R+
Sbjct: 182 VDVMEFLQLSERHNLEKFIVMQEKYNMLERD 212
Score = 37.5 bits (83), Expect = 0.87
Identities = 19/58 (32%), Positives = 36/58 (62%), Gaps = 4/58 (6%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLK-NESVNCL---LLGATSVEQFKENIHALQVYIK 473
L L ++A+ L ++SQLA++W LK E + L+GA+ +E ++N+ AL + ++
Sbjct: 276 LLGLKDVASELGITLSQLAISWLLKRGEQLGITVIPLIGASKIEHLEDNLSALNINLR 333
>UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23;
Bacteria|Rep: Sugar-phosphate dehydrogenase - Xylella
fastidiosa
Length = 362
Score = 89.4 bits (212), Expect = 2e-16
Identities = 69/235 (29%), Positives = 119/235 (50%), Gaps = 20/235 (8%)
Query: 86 TYMGNHTAMPSAVTPGLRYKNLGKSGLRVPNIGLGLWTM--LSEESIEDVVMT-ALENGI 142
T A A+ G YK+LG++GL+V I LG L++E +M+ AL++G+
Sbjct: 19 TARAQSAAAARAIGSG-NYKHLGRTGLKVSRIALGCMNFGELTDEPNSFRIMSEALDSGV 77
Query: 143 NLFDLSEAH-------CAKG----EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRS 191
NLFD ++ + KG E +GR L + RR I++ TK+Y N++
Sbjct: 78 NLFDTADVYGGPQTPDMEKGFGTSEEYIGRWLAQDKSRRDRIVLATKVYQPMGTGPNDKY 137
Query: 192 DERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG 251
LS H+ + +ASL RL+ ++ID+ +H VD P +E+ + M ++ EG + Y G
Sbjct: 138 ----LSAYHIRRACEASLKRLKTDHIDLYQMHHVDRSTPWQEIWQAMEQLVREGKITYVG 193
Query: 252 TARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
++ ++ +I A N + + EQ+ Y++ R EL + ++G+G I
Sbjct: 194 SSNFAAWDIARAQGVAESRNFLGLVSEQSLYNLIQR-TIELEVIPAVRELGIGLI 247
>UniRef50_Q3VZ80 Cluster: Aldo/keto reductase precursor; n=1;
Frankia sp. EAN1pec|Rep: Aldo/keto reductase precursor -
Frankia sp. EAN1pec
Length = 340
Score = 88.6 bits (210), Expect = 4e-16
Identities = 65/213 (30%), Positives = 103/213 (48%), Gaps = 18/213 (8%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSEESI----------EDVVMTALENGINLFDLSEAHCAK 154
+ +G+SGLR ++ LG T S E+ VV AL+ GI+ FD + + +
Sbjct: 5 RGVGRSGLRFSSLSLGGMTFGSNEAFGAIGSDPTEAARVVALALDAGIDTFDTANVY-GE 63
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNR---SDERGLSRKHVIESVKASLGR 211
E LGR+L++R R ++I TK + T H + S GLSR V+ SV+ASL R
Sbjct: 64 SEQLLGRLLRRR---RDDVVICTKARFPTSGHVGDGLPPSSSYGLSRAAVVRSVEASLRR 120
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
L + IDV+ LH D P+EE + + ++ +G V Y G + + + +A R
Sbjct: 121 LDTDRIDVLWLHMQDRSVPIEETLSATDLLVRQGKVRYLGLSNFMAYRVAEAVLTARARA 180
Query: 272 CITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
P+ Q + R+ +P H +G+G
Sbjct: 181 LEPPVALQVPWSAVSRDVERELVPAARH-LGLG 212
>UniRef50_Q82PN0 Cluster: Putative oxidoreductase; n=1; Streptomyces
avermitilis|Rep: Putative oxidoreductase - Streptomyces
avermitilis
Length = 321
Score = 87.8 bits (208), Expect = 6e-16
Identities = 58/208 (27%), Positives = 99/208 (47%), Gaps = 13/208 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIED---VVMTALENGINLFDLSEAHCAKGEAE 158
+R++ LG G V +GLG W LS + +V A + GI LFD + ++ G+AE
Sbjct: 1 MRHRTLGAGGPVVSEVGLGTWRPLSRDGRRGAARLVGAARDLGITLFDTAGSY---GDAE 57
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
+ R R S +++TK+Y+ GLSR V V+ SL L+ E+ID
Sbjct: 58 EALGIALRGAPRESYVLSTKVYYEPG------GTVAGLSRAAVRAGVERSLRALRTEHID 111
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
++ H+ D P+ E + ++ EG + ++G + W+ +I A + P+
Sbjct: 112 LLSAHRFDDRTPLAETLTAFGELLEEGKIAHYGFSEWTAQQIAAACAAATEVGVRPPVAS 171
Query: 279 QTEYHMFCREKPELYMPELYHKIGVGKI 306
Q +Y + R PE + L +G+G +
Sbjct: 172 QPQYSVLWR-VPEKAVVPLCQDLGIGTV 198
Score = 34.3 bits (75), Expect = 8.1
Identities = 17/57 (29%), Positives = 30/57 (52%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
++++ A LA + +QLAV+W L V L+GA++ EQ + A V + +
Sbjct: 243 ERVQLFARLARHQGMTPAQLAVSWVLNRPGVTSALVGASTPEQLNQTASAAGVLLSE 299
>UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 342
Score = 87.4 bits (207), Expect = 8e-16
Identities = 63/213 (29%), Positives = 111/213 (52%), Gaps = 17/213 (7%)
Query: 105 KNLGKSGLRVPNIGLG--LWTMLSEESIEDVVMTAL-ENGINLFDLSEAHCA-------- 153
++LG++GL + I G ++ ++E ++ A + G N D ++ + A
Sbjct: 30 RSLGRTGLSIAPIVFGGNVFGWTADEKTSFALLDAFFDVGFNAIDTADVYSAWVDGHVGG 89
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
+ EA +G+ LK+ +V+R +I TK+ + +NR + GLS K + E+V+ASL RLQ
Sbjct: 90 ESEAIIGKWLKQSSVKREDAVIVTKVGF------DNRGQKTGLSAKWIAEAVEASLKRLQ 143
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+YID+ L HK DP P+EE + + +G + G + +S S++ +A + N
Sbjct: 144 TDYIDLYLAHKPDPEVPLEETLAAFAKLKEQGKIRAIGCSNYSASQLQEALDVATKNNLP 203
Query: 274 TPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
V Q EY+++ R E + +L K +G I
Sbjct: 204 RYDVLQPEYNLYNRADFEGPIADLCVKEEIGVI 236
>UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter
violaceus|Rep: Gll2696 protein - Gloeobacter violaceus
Length = 345
Score = 87.4 bits (207), Expect = 8e-16
Identities = 55/166 (33%), Positives = 87/166 (52%), Gaps = 18/166 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESI------------EDVVMTALENGINLFDLSE 149
++Y LG +GL V + G T S E + +V AL+ GIN F+ ++
Sbjct: 1 MQYTRLGNTGLIVSRLAFGAMTFGSGEGAFASVYKVDQAGADRLVAQALDAGINFFNTAD 60
Query: 150 AHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
A+ A G++E+ + K RR + I TK+ T GLSR+H+I S + SL
Sbjct: 61 AY-AGGQSEI-MLGKALGNRRQDVAIATKV----GMRTGEALVHSGLSRRHIIASAEGSL 114
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARW 255
RL +YIDV L+H++DP P+EE + ++ ++ +G V Y G + W
Sbjct: 115 RRLGTDYIDVYLVHRIDPYTPLEETLEALDSLVRQGKVRYVGYSNW 160
>UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomyces
griseus|Rep: Putative oxidoreductase - Streptomyces
griseus
Length = 341
Score = 87.0 bits (206), Expect = 1e-15
Identities = 55/166 (33%), Positives = 91/166 (54%), Gaps = 10/166 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE--ESIEDVVMTAL-ENGINLFDLSEAHCAKGEAE 158
+RY+ LGK+GLRV + LG T E E+ ++ E G D ++ + A E
Sbjct: 1 MRYRYLGKTGLRVSELCLGAMTFGREADETTSHALLDRFTEAGGTFVDTADIYSAGASEE 60
Query: 159 -LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
LGR LK++ RR ++I TK+ ++ T ++RGL R H+I V++SL RL ++I
Sbjct: 61 ILGRWLKRQ--RRDDVVIATKV----RYGTGEGPNDRGLGRNHLIAGVESSLRRLGTDHI 114
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
D+ +H DP P+EE + ++ ++ G V Y G + +S ++ A
Sbjct: 115 DLYQVHAWDPGTPLEETLATLDALVTSGKVRYIGASNFSGWQLQKA 160
>UniRef50_A4FC65 Cluster: Oxidoreductase, aldo/keto reductase
family; n=1; Saccharopolyspora erythraea NRRL 2338|Rep:
Oxidoreductase, aldo/keto reductase family -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 327
Score = 86.2 bits (204), Expect = 2e-15
Identities = 59/203 (29%), Positives = 93/203 (45%), Gaps = 9/203 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGR 161
+R++ +G+SGL V I G + + ALE GI F + A G AE
Sbjct: 1 MRHRRIGRSGLLVSEISYG--NRFAHRESANCARAALEAGITTFHTAAAW-GHGAAEEAL 57
Query: 162 ILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVL 221
R RR I++ T ++W H + + GL RKH++ S+ SL RL +++DV
Sbjct: 58 AEGLREARRDDIVLCTGVFWLE--HPG--ASQFGLGRKHLMSSLHGSLRRLGTDHVDVFQ 113
Query: 222 LHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTE 281
L + D P+EE ++ V+ EG V Y GTA W+ +++ A + + +
Sbjct: 114 LWRFDHRTPLEETFLALSDVVREGKVRYVGTAEWTAEQLLRADALANELR-VPLLCNHAH 172
Query: 282 YHMFCREKPELYMPELYHKIGVG 304
Y M R MP + G+G
Sbjct: 173 YSMLWRAPESQVMPAA-ARAGIG 194
Score = 37.5 bits (83), Expect = 0.87
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
Query: 339 AREVRRVKLLNNANSMMVWSAITTG--KGLGREEITGLFAKSRFNRKYSTFSWCEEDLAV 396
A E+R L N+A+ M+W A + R I G FA + T + ++ +
Sbjct: 159 ANELRVPLLCNHAHYSMLWRAPESQVMPAAARAGI-GHFASMPLAQGILTGKYRQQRIP- 216
Query: 397 PEMRSSGSKEQVTGEEP---RTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLL 453
P R+ + + P + +++ L +A +M+QLA+AW L +E V ++
Sbjct: 217 PGSRADNDERGRSAVRPFLDASLLERVDLLRGIAEEAGLTMAQLAIAWALHHEGVASAVV 276
Query: 454 GATSVEQFKENIHA 467
GA+ Q EN A
Sbjct: 277 GASRPAQVAENARA 290
>UniRef50_Q2UT23 Cluster: Voltage-gated shaker-like K+ channel;
n=11; Pezizomycotina|Rep: Voltage-gated shaker-like K+
channel - Aspergillus oryzae
Length = 351
Score = 86.2 bits (204), Expect = 2e-15
Identities = 61/213 (28%), Positives = 107/213 (50%), Gaps = 24/213 (11%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGLWT-----------MLSEESIEDVVMTALENGINLFDLS 148
P ++Y+ LG SGL+V I LG T +L E ++ A + GIN +D +
Sbjct: 14 PKMQYQRLGNSGLKVSKIILGCMTFGNPSWEGSPWVLPEAEALPLLKKAYDCGINTWDTA 73
Query: 149 EAHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRS-----------DERGL 196
+ E +G+ L++ N+ R+ ++I TK+Y+ +N ++ GL
Sbjct: 74 NTYSNGMSEIIIGKALERYNIPRSKVVIMTKLYYPVLEPESNARPNPAINDGVLVNQMGL 133
Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
SRKH+ E+V ASL RL+ YIDV+ LH++D P EE++R ++ ++ G + Y G +
Sbjct: 134 SRKHIFEAVDASLARLKSSYIDVLQLHRIDDTHP-EEVMRALHDLVQMGKIHYLGASSMY 192
Query: 257 PSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+++ + + N Q Y++ RE+
Sbjct: 193 CWQLVRLHYAAKMNNWTVFTSMQGLYNLLYREE 225
Score = 37.9 bits (84), Expect = 0.66
Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Query: 426 LANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKKI 475
LA S CSMS LA+AW L E C ++G S+E+ + AL V + +
Sbjct: 287 LARSKGCSMSALAIAWLL--EKGACPIVGLNSIERIESASEALAVRLSDV 334
>UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Sphingomonas wittichii RW1
Length = 340
Score = 85.8 bits (203), Expect = 3e-15
Identities = 50/176 (28%), Positives = 91/176 (51%), Gaps = 18/176 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFDLS 148
+RYK LG++GL V + LG T L + ++ ++ +L+ GIN D +
Sbjct: 1 MRYKPLGRTGLHVSELCLGTMTFGGGSEGMWAPIGNLQQGDVDQLLRQSLDAGINFVDTA 60
Query: 149 EAHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKA 207
+ + E G+ ++ + R I++ TK+ ++ GLSR H++E+VKA
Sbjct: 61 NVYGDGRSERITGQAIRNLGIARDEIVVATKVMG----RMGKGPNQVGLSRYHIMEAVKA 116
Query: 208 SLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
SL RL +++ID+ +H D P+EE + ++ ++ G V Y G + W+ +I+ A
Sbjct: 117 SLTRLGLDHIDLYQVHGFDATTPIEETIEALDTLVRHGHVRYVGVSNWAAWQIVKA 172
Score = 34.3 bits (75), Expect = 8.1
Identities = 14/47 (29%), Positives = 29/47 (61%)
Query: 426 LANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+A + S++Q+A+AW L +V +++GA +Q +NI + +V +
Sbjct: 263 IAAAKGVSVAQIALAWLLHQPAVTSVIIGARRADQLADNIASTKVVL 309
>UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3;
Bacteria|Rep: Oxido-reductase/dehydratase - Pseudomonas
sp. ND6
Length = 343
Score = 85.4 bits (202), Expect = 3e-15
Identities = 59/215 (27%), Positives = 111/215 (51%), Gaps = 20/215 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-----------LSEESIEDVVMTALENGINLFDLSEA 150
+ Y++LGKSGL V + G + L + + + +V AL+ GIN FD ++
Sbjct: 1 MHYRSLGKSGLLVSELCFGTMSFGQQGYWEKIGGLDQSAAQRLVDIALDAGINFFDSADV 60
Query: 151 HC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ + E LG+ LK + R +++ TK+ + + ++ GLSR+H+I+S + SL
Sbjct: 61 YSYGQSEEILGKTLKGK---RDKVVLATKV----RGRMSQEINDVGLSRRHIIQSCENSL 113
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RL +Y+D+ ++H D + P+EE + +N +++ G V Y G + + ++M A + +
Sbjct: 114 RRLGTDYLDLYIVHSFDFMTPLEETLSTLNDLVHSGKVRYLGCSNYFAWQLMKALSISER 173
Query: 270 FNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ I Q Y + R+ E+ + L G+G
Sbjct: 174 HHWEKFISLQAYYSLLSRD-VEIELAPLCRDQGLG 207
>UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126;
Bacteria|Rep: Uncharacterized protein yghZ - Escherichia
coli (strain K12)
Length = 346
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/216 (29%), Positives = 105/216 (48%), Gaps = 19/216 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE----ESIEDVVMTALENGINLFDLSEAHCAK-GE 156
++Y+ GKSGLR+P + LGLW ES ++ A + GI FDL+ + G
Sbjct: 13 MQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGS 72
Query: 157 AE--LGRILKKRNVR-RTSIIITTKI---YWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
AE GR+L++ R +II+TK W + + G SRK+++ S+ SL
Sbjct: 73 AEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGS-------GGSRKYLLASLDQSLK 125
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQF 270
R+ +EY+D+ H+VD PMEE + + + G +Y G + +SP R++
Sbjct: 126 RMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVELLREW 185
Query: 271 NCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
I ++ Q Y++ R + + + GVG I
Sbjct: 186 K-IPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCI 220
Score = 46.8 bits (106), Expect = 0.001
Identities = 21/51 (41%), Positives = 34/51 (66%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
+ LR L +A SM+Q+A++W LK++ V +L+GA+ EQ +EN+ AL
Sbjct: 265 NSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQAL 315
>UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp.
BAL39|Rep: Oxidoreductase - Pedobacter sp. BAL39
Length = 341
Score = 84.6 bits (200), Expect = 6e-15
Identities = 48/141 (34%), Positives = 81/141 (57%), Gaps = 10/141 (7%)
Query: 120 GLWT---MLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSII 174
G+WT L ++ + +++ +++GIN D ++ + + G+AE LG+ LK V+R ++
Sbjct: 29 GMWTNIGQLQQKEVNNMLEAVIDSGINFIDTADVY-SFGQAERLLGQGLKDLQVQRDELV 87
Query: 175 ITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEEL 234
I TK+ K NN GLSR H+ +V SL RLQ+++ID++ +H VD +EE+
Sbjct: 88 IATKVLGKMKEKPNNS----GLSRYHIFNAVGDSLKRLQLDHIDILYVHGVDFKTSLEEI 143
Query: 235 VRVMNYVINEGWVMYWGTARW 255
VR +N V+ G V + W
Sbjct: 144 VRSLNDVVESGKVRHIAICNW 164
>UniRef50_Q15JF3 Cluster: Putative oxidoreductase; n=1; Streptomyces
hygroscopicus subsp. limoneus|Rep: Putative
oxidoreductase - Streptomyces hygroscopicus subsp.
limoneus
Length = 359
Score = 84.2 bits (199), Expect = 8e-15
Identities = 57/160 (35%), Positives = 93/160 (58%), Gaps = 18/160 (11%)
Query: 104 YKNLGKSGLRVPNIGLGL----------WTMLSEESIEDVVMTALENGINLFDLSEAHCA 153
Y+ LG++GL+V NI LG+ WTM + E+ + ++ AL++GIN FD + +
Sbjct: 6 YRLLGRTGLKVSNIALGVATFGSQWGPRWTMPAAEA-DTLLGVALDHGINFFDTANVY-N 63
Query: 154 KGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
+GE+E LGR L++R+ R ++I TK + T N G SR++V+ SV+ SL R
Sbjct: 64 RGESETWLGRALRRRSAR-DQVVIATKCGYRTDPRDVNSG---GCSRRNVVASVERSLRR 119
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG 251
L ++ID++ LH D V P+EE + +++ G + Y G
Sbjct: 120 LGTDHIDLLYLHLWDGVTPVEESLAAAADLVSAGKIRYVG 159
>UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep:
Aldo/keto reductase - Caldivirga maquilingensis IC-167
Length = 351
Score = 84.2 bits (199), Expect = 8e-15
Identities = 66/227 (29%), Positives = 106/227 (46%), Gaps = 32/227 (14%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFDLS 148
+RY G SGL+V + LGLW + + EE ++ A++ GIN D +
Sbjct: 1 MRYVRFGNSGLQVSQLCLGLWHLPPSRVRDEYGVYKVDEEESVRIIRRAIDLGINFIDTA 60
Query: 149 EA-----------HCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS 197
H E LG+ +K + R S++I TK+ N GLS
Sbjct: 61 NVYHGTMQGPDYIHAGNAERILGKAIKGYD--RESLVIATKVRGRMAPWPNGE----GLS 114
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
RKH+ +K SL RL Y+D+ L+H+ DP P+EE + + ++++G V Y G + + P
Sbjct: 115 RKHIRWQIKESLRRLDTSYVDIYLMHRPDPSTPIEETLDTLKDLVSQGLVNYVGESYFHP 174
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+I RQ + + I Q Y++ R+ + +P L K G+G
Sbjct: 175 EDIEYIVNYSRQIH-LPFIAMQEPYNLIERDIEKDKIP-LASKYGLG 219
Score = 37.5 bits (83), Expect = 0.87
Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 7/81 (8%)
Query: 396 VPEMRSSGSKEQVTGE--EPRTYGDKLRDLANLANSLNCSMSQLAVAWCL-KNESVNCL- 451
+PEM +G +++ P T +R+ LA L + +QLA+AW L K+E +
Sbjct: 239 IPEMSRAGYVDEIRWRYLTPETL-KAMREFHELAMELGVTDAQLALAWILRKSEEMGVTV 297
Query: 452 --LLGATSVEQFKENIHALQV 470
++GATSV Q ++++ ++ V
Sbjct: 298 IPIIGATSVTQLEDDVGSINV 318
>UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 368
Score = 83.8 bits (198), Expect = 1e-14
Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 30/183 (16%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFDLS 148
+ Y G SGL+V LG W + + EE + ++ A++ G+N FD +
Sbjct: 18 MEYMKFGNSGLKVSKFCLGTWHLPPSKERDSYGVYKVDEEESKKTIVKAIDLGVNFFDTA 77
Query: 149 EA-----------HCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS 197
H E LG +K + R S+++ TK+ H N GLS
Sbjct: 78 NVYHGVMQGPDVFHVGNAERILGEAIKGYD--RESLVLATKVRGKMAEHANGE----GLS 131
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
RKH++ V+ SL RL +YID+ L+H+ DP P+EE + + ++ +G + Y G + + P
Sbjct: 132 RKHIMWQVRESLKRLNTDYIDIYLMHRPDPDTPIEETMETFHDLVRQGKIHYIGESYFDP 191
Query: 258 SEI 260
++I
Sbjct: 192 TDI 194
Score = 40.3 bits (90), Expect = 0.12
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 4/57 (7%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCL----LLGATSVEQFKENIHALQVYI 472
LR+ +A L + +QLA+AW K + +N + ++G T + Q +ENI +L V I
Sbjct: 281 LREFHEIAKELGVTDTQLALAWIFKIQEINQITIVPIIGVTKINQLEENIESLNVKI 337
>UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 344
Score = 83.8 bits (198), Expect = 1e-14
Identities = 52/160 (32%), Positives = 88/160 (55%), Gaps = 17/160 (10%)
Query: 104 YKNLGKSGLRVPNIGLGL--------WTMLSEESIEDVVMTALENGINLFDLSEAHCAKG 155
Y LG +GL V + LG W + E ++ AL+ GIN FD + A+ + G
Sbjct: 23 YTTLGSTGLDVSELCLGTMNFGSAEPWMLNDEAESRRILERALDLGINFFDTANAY-SNG 81
Query: 156 EAELGRILKKR--NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
E+E RIL + + R +++ +K+Y F ++ + GLS+KH+I+ A+L RL
Sbjct: 82 ESE--RILGEAVDSAHRGELVLASKVY----FDMHDGPNGSGLSKKHIIDQCHATLDRLG 135
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
V+Y+D+ +H+ D P+EE + + Y+++EG V Y G +
Sbjct: 136 VDYLDLYQIHRWDDDTPIEETLDALTYLVDEGLVRYIGAS 175
>UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative oxidoreductase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 359
Score = 83.4 bits (197), Expect = 1e-14
Identities = 61/212 (28%), Positives = 102/212 (48%), Gaps = 18/212 (8%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM-----------LSEESIEDVVMTALENGINLFDLSEAHC 152
Y LG SGL V LG +S++ ++ AL+ GIN FD + +
Sbjct: 3 YTQLGNSGLSVSKYALGSIPFTGTNGFENAGGMSQDMTNHMIDYALDQGINQFDTANLY- 61
Query: 153 AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
+KG++E+ + K +R ++I++K T F + ++ G R ++ S+ SL RL
Sbjct: 62 SKGDSEIA-LGKAIRDKRHQMVISSK----TGFQLTDNPNDGGAGRVNIEHSIDESLQRL 116
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
+YID+ H D P+EE ++VMN +I +G + YWG + +S + +T +
Sbjct: 117 NTDYIDLYYTHLWDGQTPVEETIQVMNDLIQKGKIRYWGVSNYSGWALAKTHTLAVANHM 176
Query: 273 ITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
PI +Q Y RE +P ++GVG
Sbjct: 177 APPIAQQIYYTPESREAEYELLP-AGKELGVG 207
>UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2;
Bacteria|Rep: Putative aldo/keto reductase -
Lactobacillus sakei subsp. sakei (strain 23K)
Length = 328
Score = 83.0 bits (196), Expect = 2e-14
Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 15/193 (7%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEE----SIEDVVMTALENGINLFDLSEAH---CAKGE 156
Y+ +G SGL++P I LGLW E + ++++ A + GI FDL+ + E
Sbjct: 14 YRRVGHSGLKLPAISLGLWHNFGETDKVATQKEIIFGAFDMGITHFDLANNYGPPAGSAE 73
Query: 157 AELGRILKKRNVR-RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
GRIL + R +II++K + + E G S+K++I S SL R+Q++
Sbjct: 74 ENFGRILHSDLKQYRDEMIISSKAGY---YMWPGPYGEWG-SKKNLIASCDQSLQRMQLD 129
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ H+ DP P+EE R ++ ++++G +Y G + +S + R+ TP
Sbjct: 130 YVDIFYSHRPDPETPIEETARALDLLVHQGKALYIGISNYSAEQTKAITKIFRELG--TP 187
Query: 276 -IVEQTEYHMFCR 287
I+ Q Y+M R
Sbjct: 188 FIIHQPRYNMLDR 200
Score = 38.7 bits (86), Expect = 0.38
Identities = 15/49 (30%), Positives = 34/49 (69%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
+++L +A S++++A+AW L+ +V +L+GA+ + Q ++++HAL
Sbjct: 262 VQELNKIAQQRGQSLAEMALAWNLQQPTVASVLVGASRLSQLQDSVHAL 310
>UniRef50_A1CWM8 Cluster: Aldo-keto reductase, putative; n=14;
Ascomycota|Rep: Aldo-keto reductase, putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 369
Score = 83.0 bits (196), Expect = 2e-14
Identities = 68/225 (30%), Positives = 104/225 (46%), Gaps = 27/225 (12%)
Query: 107 LGKSGLRVPNIGLGL-------WT--MLSEESIEDVVMTALENGINLFDLSEAHC-AKGE 156
LG SGL++ I LG W +L E+ ++ A + GIN +D ++ + E
Sbjct: 30 LGNSGLKISKIILGAMSYGSKKWQDWVLDEDEALPLIEHAYKRGINTWDTADTYSHGLSE 89
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTN----------NRSD-----ERGLSRKHV 201
+G+ LKK ++ R ++I TK Y+ TN NR+D GLSRKH+
Sbjct: 90 EIIGKALKKYSIPRHRVVILTKCYFGVTDETNESKMPPISACNRNDGDWVNRVGLSRKHI 149
Query: 202 IESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIM 261
++V AS+ RL YIDV+ +H++D P EE+++ +N V+ G V Y G + + E
Sbjct: 150 FDAVDASVKRLGT-YIDVLQIHRLDRETPREEIMKALNDVVESGKVRYIGASTMAAWE-F 207
Query: 262 DAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
N N + YH + E M GVG I
Sbjct: 208 QTLQNIAARNGWHQFISMQNYHNLLAREEEREMIPYCLDSGVGLI 252
Score = 34.3 bits (75), Expect = 8.1
Identities = 17/47 (36%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 426 LANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+A N SM+Q+A+AW L + N +LG +S E+ E + A++V +
Sbjct: 302 IAKKKNISMAQVAIAWVLSHPKEN-PILGLSSKERIDEAVAAIKVQL 347
>UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep:
Aldo/keto reductase - Frankia sp. (strain CcI3)
Length = 348
Score = 82.6 bits (195), Expect = 2e-14
Identities = 58/210 (27%), Positives = 108/210 (51%), Gaps = 16/210 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-----LSEESIEDVVMTALENGINLFDLSEAHCAKGE 156
++Y+ L ++G+ V LG + E ++ AL+ GIN D ++ + ++GE
Sbjct: 1 MKYRKLARTGVEVSTQCLGAMMFGAFGNTDHDECERIIHRALDAGINFLDTADIY-SQGE 59
Query: 157 AE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
+E +GR +K RR +++ TK + N+R G SR+ +I +V+ SL RL
Sbjct: 60 SEEIVGRAIK---TRRDDVVLATKCFSPMGDERNSR----GGSRRWIIRAVEDSLRRLGT 112
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+YID+ +H+ D +E+ + ++ +++ G V Y G++ + I++A R+ N
Sbjct: 113 DYIDLYQVHRHDWDTDLEDTLGALSDLVHAGKVRYLGSSSFPADWIVEAQWAARRRNSER 172
Query: 275 PIVEQTEYHMFCREKPELYMPELY-HKIGV 303
+ EQ +Y +F R E +P H IG+
Sbjct: 173 FVCEQPQYSIFARSIEEAVLPAAQRHTIGI 202
>UniRef50_P80874 Cluster: General stress protein 69; n=16; cellular
organisms|Rep: General stress protein 69 - Bacillus
subtilis
Length = 331
Score = 82.6 bits (195), Expect = 2e-14
Identities = 58/202 (28%), Positives = 98/202 (48%), Gaps = 19/202 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAH-CA 153
+ Y ++ +G+ IGLG W + E++ + + AL+ GI L D + A+
Sbjct: 1 MEYTSIADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFG 60
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
+ E +G+ +K+ +R +I+ TK T N R +R ++E V+ SL RLQ
Sbjct: 61 QSEEIVGKAIKEYG-KRDQVILATK----TALDWKNNQLFRHANRARIVEEVENSLKRLQ 115
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+YID+ +H DP+ P+EE VM + + G + G + +S E MD + + I
Sbjct: 116 TDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAIGVSNFS-IEQMDTFRAVAPLHTI 174
Query: 274 TPIVEQTEYHMFCREKPELYMP 295
P Y++F RE E +P
Sbjct: 175 QP-----PYNLFEREMEESVLP 191
>UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_03000103;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000103 - Ferroplasma acidarmanus fer1
Length = 342
Score = 81.4 bits (192), Expect = 5e-14
Identities = 56/212 (26%), Positives = 108/212 (50%), Gaps = 31/212 (14%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM------------LSEESIEDVVMTALENGINLFDLSE 149
++Y N+GKSGL+V + +G W + ++EE + + A + GIN +D ++
Sbjct: 1 MKYVNVGKSGLKVSTVAIGTWHLPGSGQFVNKVESVNEEEFKKIFKKAYDFGINFYDTAD 60
Query: 150 AH---------CAK--GEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGL 196
+ C + G +E LG I+K + R S++I+TK+ ++ N+ GL
Sbjct: 61 IYHGRVENNEDCIECTGNSERVLGNIIKDYD--RESLVISTKVAGPMNYYVNSS----GL 114
Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
SRKH++ +K+SL RL+ +Y+D+ H D P+ E ++ M+++++ Y G + +
Sbjct: 115 SRKHIMHGIKSSLERLKTDYVDLYQFHWSDNDTPLIETLKAMSHIVDLDLSRYIGMSNVN 174
Query: 257 PSEIMDAYTNCRQFNCITPIVEQTEYHMFCRE 288
+I + ++N I Q Y++ R+
Sbjct: 175 ACDIPEFMNLSEKYNLNNFITMQEAYNILDRK 206
Score = 36.7 bits (81), Expect = 1.5
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLK-NESVNCL---LLGATSVEQFKENIHALQVYIK 473
++ L A+ + ++SQLA+AW LK +N LLG T+++ +NI+AL V +K
Sbjct: 264 VKKLKEFADENDITLSQLAIAWLLKRGAELNIKIIPLLGITNIKYLDDNINALNVNLK 321
>UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6;
Bacteria|Rep: Aldo-keto oxidoreductase - Nostoc commune
UTEX 584
Length = 374
Score = 81.4 bits (192), Expect = 5e-14
Identities = 64/224 (28%), Positives = 103/224 (45%), Gaps = 13/224 (5%)
Query: 91 HTAMPSAVTPGLRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDL 147
HT + ++ L NLGK+GL V + LG T EE+ ++ TA + GIN D
Sbjct: 34 HTFSINNISMTLPTTNLGKTGLTVSRLCLGTMTFGLQTDEETSRQILDTAADGGINFLDT 93
Query: 148 SEAH-CAKGEAELGR----ILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVI 202
++ + G A GR + + +R I+ TK ++G SRKH++
Sbjct: 94 ADVYPLGGGLATAGRTEEIVGRWLKGKREHFILATKCVG----RVGPAPWDQGASRKHIL 149
Query: 203 ESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
+++ ASL RL +YID+ LH D P++E + ++ V+ G V Y G + + +
Sbjct: 150 DAIDASLRRLGTDYIDLYQLHSDDASTPLDETLEALDAVVRAGKVRYIGVSNFLAYRLAR 209
Query: 263 AYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
A N I Q Y++ RE +P L + G+G I
Sbjct: 210 ALGRAETRNLTKFISIQPRYNLLFREIERELLP-LAKEEGLGVI 252
Score = 39.5 bits (88), Expect = 0.22
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
++LR +A+LA S++ LAVAW L N + ++GA+ EQ +N+ AL++
Sbjct: 301 EELRTVADLAGF---SLTTLAVAWVLSNPIITAPIIGASRPEQLADNLKALEL 350
>UniRef50_A6WAF9 Cluster: Aldo/keto reductase; n=1; Kineococcus
radiotolerans SRS30216|Rep: Aldo/keto reductase -
Kineococcus radiotolerans SRS30216
Length = 341
Score = 81.4 bits (192), Expect = 5e-14
Identities = 61/205 (29%), Positives = 100/205 (48%), Gaps = 18/205 (8%)
Query: 107 LGKSGLRVP-----NIGLGLWTMLSEESIEDVVM-TALENGINLFDLSEAHCA-KGEAEL 159
LG GLRV +G+ +W +++ + AL++G+ FD +EA+ + E L
Sbjct: 20 LGSQGLRVSAQALGTMGMSVWYGPRDDAESLATLHQALDSGVTFFDTAEAYGPFRNEQLL 79
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
++L N RR + TK W T F + S + S +H +++ SL L VE +DV
Sbjct: 80 AQVL---NTRRAEATVATK--WGTDFAPDGTSLGQDGSAEHCRRAIERSLTHLGVEAVDV 134
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQ 279
LH+VDP P+EE V M ++ G V + G +P I A+ +T + Q
Sbjct: 135 YYLHRVDPKVPVEESVGAMGELVTAGKVRFIGICEAAPDTIRRAHATFP----LTAV--Q 188
Query: 280 TEYHMFCREKPELYMPELYHKIGVG 304
+EY +F R+ + E ++G+G
Sbjct: 189 SEYSLFARDVERNGVLETVRELGIG 213
>UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia
phytofirmans PsJN|Rep: Aldo/keto reductase -
Burkholderia phytofirmans PsJN
Length = 339
Score = 81.4 bits (192), Expect = 5e-14
Identities = 48/172 (27%), Positives = 90/172 (52%), Gaps = 17/172 (9%)
Query: 102 LRYKNLGKSGLRVPNI---------GLGLW---TMLSEESIEDVVMTALENGINLFDLSE 149
+ Y LG+SGLR+ + G G+W L +V A+E GINL D ++
Sbjct: 1 MEYNTLGRSGLRISRLCLGAMTFGAGTGIWGEIAGLDRARAARLVSIAVEQGINLIDTAD 60
Query: 150 AHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKAS 208
A+ + E +G++L + + +++ TK+ + T ++ GL R H++ SV+ S
Sbjct: 61 AYSQGQSEVVVGQVLADLGLDESRMLVATKV----RLRTGPGHNDVGLGRSHIMRSVETS 116
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
L R+ ++ID+ LH D + P+EE +R ++ ++ +G V + G +S ++
Sbjct: 117 LRRIGRDHIDLFQLHDRDALVPLEETLRALDDLVTQGKVRHIGVCNFSAGDL 168
Score = 38.7 bits (86), Expect = 0.38
Identities = 18/59 (30%), Positives = 33/59 (55%)
Query: 412 EPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
+P +R L +A L+ S +Q+A+AW L+ V +++GA + EQ N+ A ++
Sbjct: 246 DPARADPVVRVLQEVATELDASPAQVALAWILQRREVCSVIIGARTAEQLAANLDAQRI 304
>UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 370
Score = 81.0 bits (191), Expect = 7e-14
Identities = 56/207 (27%), Positives = 100/207 (48%), Gaps = 21/207 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGL-----------WTMLSEESIEDVVMTALENGINLFDLSEA 150
+ Y+ LG+SGL VP + LG W ++ LE G+++FD ++
Sbjct: 30 MEYRRLGRSGLMVPALSLGTGTFGGVGRLAAWGTTDASEARRLLDICLEAGVSMFDTADV 89
Query: 151 HCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKAS 208
+ + GE+E LG +K R R ++I+TK F + ++ G SR+H++ ++ S
Sbjct: 90 Y-SLGESERVLGEAIKGR---RDKVLISTK----ATFRFGDGPNDIGSSRQHLLAAIDGS 141
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCR 268
L RL +YID+ LH D P EE++ ++ ++ G + Y G + +S +M + +
Sbjct: 142 LARLGTDYIDLFQLHGFDAFTPPEEVLATLDVLVRAGKIRYVGVSNFSGWHLMKSLSIAD 201
Query: 269 QFNCITPIVEQTEYHMFCREKPELYMP 295
+ + QT Y + R+ MP
Sbjct: 202 KHGFPRYVANQTYYSLIGRDYEWELMP 228
Score = 35.1 bits (77), Expect = 4.7
Identities = 15/43 (34%), Positives = 28/43 (65%)
Query: 426 LANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
+A S+SQ+A+ W L+ +V+ L++GA + Q +EN+ A+
Sbjct: 289 VARETGKSVSQIALNWLLQRPTVSTLIIGARNETQLRENLGAV 331
>UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|Rep:
Aldo/keto reductase - Roseiflexus sp. RS-1
Length = 333
Score = 81.0 bits (191), Expect = 7e-14
Identities = 54/199 (27%), Positives = 100/199 (50%), Gaps = 11/199 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
+ Y+ G++G+RV + +G E ++ AL+ GIN+FD + ++ GE+E
Sbjct: 1 MEYRLFGRTGVRVAPLCIGAMNFGNPTDEAEALRIIDRALDAGINMFDTANSY-NNGESE 59
Query: 159 --LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+GR L R+ +R + + TK + F ++RG SR H++ + + SL RLQ ++
Sbjct: 60 RIIGRALA-RDGKRDRVFLATKGH----FPVGPGPNDRGNSRLHLMRACEDSLRRLQTDH 114
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ +H+ DP P+EE + + ++ +G V Y G + +M+A + +
Sbjct: 115 IDLYQIHRPDPATPVEETLAALTDLVRQGKVRYVGCSTHPAWRVMEALMVSELKGYVRYV 174
Query: 277 VEQTEYHMFCREKPELYMP 295
EQ Y++ R +P
Sbjct: 175 SEQPPYNLLDRRIENELLP 193
>UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzyme;
n=3; Lactobacillales|Rep: Aryl-alcohol dehydrogenase
related enzyme - Lactobacillus casei (strain ATCC 334)
Length = 334
Score = 80.6 bits (190), Expect = 9e-14
Identities = 61/217 (28%), Positives = 103/217 (47%), Gaps = 22/217 (10%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSEESI----EDVVMTALENGINLFDLSEAHCAKGEAE-- 158
++ GK+GL +P I LGLW V++ A ++G+ FD++ H G+ E
Sbjct: 15 RHAGKTGLMLPAISLGLWQHYGNLDPFGPRRSVILDAFDHGVFHFDVAN-HYGNGDHEPG 73
Query: 159 -------LGRILKKR-NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
LG+IL R ++I+TK+ + + H G SRK VI+ + SL
Sbjct: 74 FGSSESLLGQILATDLKAYRDELVISTKVGY--EIHPGPYGV--GTSRKAVIQGLNDSLK 129
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQF 270
RLQ++Y+D+ H+ D +EE V ++ + +G +Y G + + + DA +
Sbjct: 130 RLQLDYVDIYYAHRFDDTVDLEETVNALDQTVRDGKALYIGISNFDTQQTKDAIAMFKDL 189
Query: 271 NCITP-IVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ TP ++ Q Y+MF RE + + G G I
Sbjct: 190 H--TPFVLNQFSYNMFNREAETSGLTKALQADGAGLI 224
Score = 41.1 bits (92), Expect = 0.071
Identities = 16/51 (31%), Positives = 34/51 (66%)
Query: 419 KLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQ 469
KL +L +A+ +++Q+A+AW L++ V +++G TSV+ ++N+ A +
Sbjct: 266 KLNELNEVAHDRGQTLTQMALAWLLRDPVVTSVIIGTTSVDHLEDNLKATE 316
>UniRef50_Q6FV29 Cluster: Similar to tr|Q02895 Saccharomyces
cerevisiae YPL088w; n=5; Saccharomycetales|Rep: Similar
to tr|Q02895 Saccharomyces cerevisiae YPL088w - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 346
Score = 80.6 bits (190), Expect = 9e-14
Identities = 50/189 (26%), Positives = 94/189 (49%), Gaps = 16/189 (8%)
Query: 122 WTMLSEESIEDVVMTALENGINLFDLSEAHC-AKGEAELGRILKKRNVRRTSIIITTKIY 180
W + +E I ++ A + G+ +D ++ + E L +K ++R +++I TK++
Sbjct: 37 WVLEDKEKIFGILKHAYDRGLRTYDTADVYSNGYSERLLKEFFEKYQIKRETVVIMTKVF 96
Query: 181 WST----KFHT-----NNRSD-----ERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVD 226
+ H N+ D +RGLSRKH++E VK S RL YIDV+ +H++D
Sbjct: 97 FGVDEDLNLHHGLKAYNDHDDLILTNQRGLSRKHILEGVKNSTERLGT-YIDVLQIHRLD 155
Query: 227 PVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFC 286
PM+E+++ +N V+ G+ Y G++ +E + + N + Q+ Y++
Sbjct: 156 KETPMKEIMKALNDVVEAGYARYIGSSSMLATEFAELQFIAEKHNWFQFVSLQSFYNLLN 215
Query: 287 REKPELYMP 295
RE +P
Sbjct: 216 REDEREIIP 224
>UniRef50_Q02895 Cluster: Putative aryl-alcohol dehydrogenase
YPL088W; n=22; Ascomycota|Rep: Putative aryl-alcohol
dehydrogenase YPL088W - Saccharomyces cerevisiae
(Baker's yeast)
Length = 342
Score = 80.6 bits (190), Expect = 9e-14
Identities = 58/222 (26%), Positives = 107/222 (48%), Gaps = 26/222 (11%)
Query: 107 LGKSGLRVPNIGLGL----------WTMLSEESIEDVVMTALENGINLFDLSEAHC-AKG 155
LG SGL++ I +G W + + I ++ + G+ FD ++ +
Sbjct: 9 LGNSGLKISPIVIGCMSYGSKKWADWVIEDKTQIFKIMKHCYDKGLRTFDTADFYSNGLS 68
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWST-------------KFHTNNRSDERGLSRKHVI 202
E + L+ +++R +++I TKIY+ +F + S++RGLSRKH+I
Sbjct: 69 ERIIKEFLEYYSIKRETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQRGLSRKHII 128
Query: 203 ESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
V+ S+ RL YID++ +H++D PM+E+++ +N V+ G V Y G + +E +
Sbjct: 129 AGVENSVKRLGT-YIDLLQIHRLDHETPMKEIMKALNDVVEAGHVRYIGASSMLATEFAE 187
Query: 263 AYTNCRQFNCITPIVEQTEYHMFCREKPELYMP-ELYHKIGV 303
++ I Q+ Y++ RE +P H IG+
Sbjct: 188 LQFTADKYGWFQFISSQSYYNLLYREDERELIPFAKRHNIGL 229
>UniRef50_A7TRU8 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 341
Score = 80.2 bits (189), Expect = 1e-13
Identities = 59/218 (27%), Positives = 103/218 (47%), Gaps = 26/218 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGL----------WTMLSEESIEDVVMTALENGINLFDLSEAH 151
L+ K G +GL+V I +G W E I ++ A + G+ +D + +
Sbjct: 4 LQQKKFGNTGLKVSPIIIGCMSFGSKKWSEWVEDDREKIFKILKYAYDKGLRTYDTANVY 63
Query: 152 CAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTN------------NRSDERGLS 197
+ GE+E LG LK + R ++II TK+Y+ T + + N + GLS
Sbjct: 64 -SNGESEIILGEFLKNYKIPRETVIIMTKLYFPTNDNADYDIFSMTPEAILNNVNITGLS 122
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
RK++I S + S+ RL Y D++ +H+ DP P EE +R +N ++ +G Y G +
Sbjct: 123 RKNIINSARDSVRRLGT-YADIIQIHRADPDTPFEETMRALNDIVVDGLTRYIGASSMLA 181
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMP 295
+E ++ + + I Q+ Y++ RE +P
Sbjct: 182 TEFVEMQFIAEKNDWFKFINSQSCYNLLYREDERELIP 219
>UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;
n=5; Bacteria|Rep: Oxido-reductase, and dehydratase;
MocA - Rhizobium loti (Mesorhizobium loti)
Length = 347
Score = 79.8 bits (188), Expect = 2e-13
Identities = 54/206 (26%), Positives = 100/206 (48%), Gaps = 18/206 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM--------LSEESIED---VVMTALENGINLFDLSEA 150
+ Y+ LG+SGL+V + LG T + + + ++ ++ GINL D +
Sbjct: 1 MEYRTLGRSGLKVSTLTLGTMTFGGTGPFAAVGNSDLGEARRMIDMCIDAGINLIDTANV 60
Query: 151 HC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ E +G L + RR ++I +K + + ++ GLSR H+I + SL
Sbjct: 61 YSNGLSEEIIGEALGGK--RRNDVLIASK----ARMRIGSGPNDEGLSRHHLIRECEKSL 114
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RL+ + ID+ +H+ D + P+EE V ++ ++N+G V Y G + WS ++M A +
Sbjct: 115 KRLKTDVIDIYFVHQWDGLTPVEETVAALDTLVNQGKVRYIGCSNWSGWQVMKALSISDS 174
Query: 270 FNCITPIVEQTEYHMFCREKPELYMP 295
+ + +Q Y + RE +P
Sbjct: 175 RHQQRFVTQQIHYTLEAREAEYELLP 200
>UniRef50_Q13PH6 Cluster: Putative oxidoreductase; n=1; Burkholderia
xenovorans LB400|Rep: Putative oxidoreductase -
Burkholderia xenovorans (strain LB400)
Length = 326
Score = 79.8 bits (188), Expect = 2e-13
Identities = 66/205 (32%), Positives = 96/205 (46%), Gaps = 17/205 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGL-------WT--MLSEESIEDVVMTALENGINLFDLSEAHC 152
+ Y G+S LRV IGLG W +L+E D+V TA++ GIN D + +
Sbjct: 1 MEYVRFGRSSLRVSRIGLGAMGFGDPAWRKWVLAENDAWDIVRTAVDAGINFVDTCDFYS 60
Query: 153 A-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
A E +G L R +++ TK+ H N RG SRKH+ +V+ASL R
Sbjct: 61 AGASETIIGNTLWDC-APRDQMVLATKLGNPMGTHPN----ARGYSRKHIFSAVEASLRR 115
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
L+ +YID++ H P +EELV + ++ G V Y G A P+ N Q +
Sbjct: 116 LKTDYIDLLQTHIWQPETDLEELVIAFDELVRSGKVRYVG-ATTMPAWAFVQCVNIAQRS 174
Query: 272 CITPIVE-QTEYHMFCREKPELYMP 295
+ Q EY++ RE MP
Sbjct: 175 GRSAFASMQCEYNVCHREAERELMP 199
Score = 35.5 bits (78), Expect = 3.5
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
+A +A +C SQ+A+AW L+ + + GAT K + AL++
Sbjct: 255 VARIAAKHDCEPSQVALAWALRQPGITSPIFGATQTAHVKSAVDALKL 302
>UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep:
Aldo/keto reductase - Arthrobacter sp. (strain FB24)
Length = 325
Score = 79.8 bits (188), Expect = 2e-13
Identities = 58/208 (27%), Positives = 100/208 (48%), Gaps = 9/208 (4%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGE 156
Y+ LG SGL V +GLG + S+E + VV AL+ GI LFD+++ + +
Sbjct: 4 YRRLGNSGLTVSVVGLGCNNLGRANTVTESQEGTDAVVHAALDAGITLFDVADTYGREPG 63
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+ K RR I+ TK + RG SR++++++ +ASL RL ++
Sbjct: 64 VSETMLGKALAGRRGDAIVATKFGMDMRGANGKDFGARG-SRRYIVQAAEASLRRLGTDW 122
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ H DP+ P++E + ++ ++ G V Y G + + +I +A R + I
Sbjct: 123 IDLYQFHTPDPLTPIDETLAALDDLVTSGKVRYIGHSNRAGWQIAEAEFVARARGGVRFI 182
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVG 304
Q Y++ R + EL + G+G
Sbjct: 183 STQNHYNLLDR-RAELEVTPAAEAYGLG 209
>UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular
organisms|Rep: Lmo2005 protein - Listeria monocytogenes
Length = 331
Score = 79.4 bits (187), Expect = 2e-13
Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 18/207 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGL--------WT---MLSEESIEDVVMTALENGINLFDLSEA 150
++Y G +G+ V I LG W +L E + ++ AL+ GIN FD +
Sbjct: 1 MKYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLDEANSRPIIKKALDLGINFFDTANI 60
Query: 151 HCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKAS 208
+ + GE+E +GR LK R I++ TK+ + + +R + GLSRK ++ + S
Sbjct: 61 Y-SYGESEKIVGRALKDY-ANRDDIVLATKVQQTMR---PDRPNSGGLSRKTILSEIDHS 115
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCR 268
L RL+ +Y+D+ ++H+ D P+EE + ++ V+ G Y G + + A
Sbjct: 116 LKRLETDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGASAMYAWQFQKAQRVAE 175
Query: 269 QFNCITPIVEQTEYHMFCREKPELYMP 295
+ + Q Y+M RE+ +P
Sbjct: 176 RNGWTKFVSMQNHYNMIYREEEREMIP 202
>UniRef50_Q0LSA5 Cluster: Aldo/keto reductase; n=2;
Proteobacteria|Rep: Aldo/keto reductase - Caulobacter
sp. K31
Length = 368
Score = 79.4 bits (187), Expect = 2e-13
Identities = 58/199 (29%), Positives = 91/199 (45%), Gaps = 12/199 (6%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM------LSEESIEDVVMTALENGINLFDLSEAHCA-KGE 156
Y+ LG+SGL V + LG T + E V +E G NL D ++ + A GE
Sbjct: 6 YRPLGRSGLIVSPLALGTMTFGVARWGMERPDAEAVFDAYVEAGGNLIDTADVYAAGAGE 65
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
LG +L +R R +++ TK + F T G KH+ +++ SL RL+ +Y
Sbjct: 66 TMLGEMLAERG-NRHELVLATK----SGFATGRGPHAGGNGAKHIHAALEGSLRRLKTDY 120
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ +H D V P E+L+ M+ ++ G + YWG + + T PI
Sbjct: 121 IDLYWIHVWDSVTPPEQLLETMSALVRAGKIRYWGMSNTPAWYVARVVTLAMARGQPGPI 180
Query: 277 VEQTEYHMFCREKPELYMP 295
Q Y + RE ++P
Sbjct: 181 ALQYFYSLVSREIEAEHVP 199
>UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n=6;
Bacteria|Rep: Aryl-alcohol dehydrogenase (NADP(+)) -
Arthrobacter sp. (strain FB24)
Length = 343
Score = 79.4 bits (187), Expect = 2e-13
Identities = 53/193 (27%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALEN----GINLFDLSEAHCAKGEA 157
++Y+ LG SG V N LG T E+ E+ L++ G N D ++ + ++G +
Sbjct: 1 MQYRTLGNSGAVVSNYALGTMTF-GAEATEETSFAILDDYFAAGGNFIDTADVY-SQGVS 58
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +GR L R + ++ TK +F ++ G SR+H+ ++ SL RL VE
Sbjct: 59 EEIIGRWLAARPDVKDRAVLATK----GRFPMGQAPNDLGTSRRHLTRALDDSLRRLGVE 114
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
ID+ +H DP+ P+EE +R ++ ++ G + Y+G + + ++ A + P
Sbjct: 115 QIDLYQMHAWDPITPLEETLRFLHDSVSSGKIAYYGFSNFLGWQLTKAVHLAKAHGWSAP 174
Query: 276 IVEQTEYHMFCRE 288
+ Q +Y + RE
Sbjct: 175 VTLQPQYSLLVRE 187
Score = 38.7 bits (86), Expect = 0.38
Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 407 QVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIH 466
Q ++PRT+ + + + +A S SQ+A+AW +V ++LGA + EQ +N+
Sbjct: 242 QARNDDPRTW-EVIGTVEKIAADHGVSASQVALAWLADRPAVTSVILGARTTEQLADNLA 300
Query: 467 A 467
A
Sbjct: 301 A 301
>UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductases
(related to aryl-alcohol dehydrogenases); n=1;
Brevibacterium linens BL2|Rep: COG0667: Predicted
oxidoreductases (related to aryl-alcohol dehydrogenases)
- Brevibacterium linens BL2
Length = 342
Score = 78.6 bits (185), Expect = 4e-13
Identities = 49/170 (28%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 137 ALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDER 194
ALE G+N D + + A G+AE LG+I+ R R +++T+K + T + ++
Sbjct: 32 ALERGVNFIDTANLYSA-GDAERVLGKIMGNR---RDDVVLTSK----ARMPTGDGPNDS 83
Query: 195 GLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTAR 254
G SR H+I +V SL RL+ +++D++ +H+ D P+ E + +N +I G + YWG +
Sbjct: 84 GASRHHLIRAVDDSLSRLRTDHLDLLYIHQWDGQTPITETIATVNELIRAGKIRYWGVSN 143
Query: 255 WSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
++ ++ + PI +Q Y RE +P +GVG
Sbjct: 144 FNGWQLAKTVYEAKLAGLEPPIAQQVYYTPEAREIEYEIIPAA-RDLGVG 192
>UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Rep:
Oxidoreductase; MocA - Rhizobium loti (Mesorhizobium
loti)
Length = 344
Score = 78.6 bits (185), Expect = 4e-13
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 20/205 (9%)
Query: 104 YKNLGKSGLRVPNIGLGL------------WTMLSEESIEDVVMTALENGINLFDLSEAH 151
Y+ LG SGL+VP + G W + +V LE G+NLFD ++ +
Sbjct: 3 YRRLGASGLKVPALSFGAGTFGGSGPLFGAWGNSDAKEARRLVDICLEAGVNLFDTADVY 62
Query: 152 C-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
E LG +K R R +++I+TK T + + G SR +I+SV A+L
Sbjct: 63 SNGASEEVLGEAIKGR---RDAVLISTK----TSLPMGDGPADYGSSRSRLIKSVDAALK 115
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQF 270
RL +YID++ LH D P+EE++ ++ ++ G + Y G + +S ++M + +
Sbjct: 116 RLGTDYIDLLQLHAFDAGTPVEEVLSTLDELVRAGKLRYVGVSNFSGWQVMKSLAQADRH 175
Query: 271 NCITPIVEQTEYHMFCREKPELYMP 295
+ Q Y + R+ MP
Sbjct: 176 GYPRYVAHQVYYSLVGRDYEWELMP 200
>UniRef50_A6VR43 Cluster: Aldo/keto reductase precursor; n=3;
Pasteurellaceae|Rep: Aldo/keto reductase precursor -
Actinobacillus succinogenes 130Z
Length = 381
Score = 78.2 bits (184), Expect = 5e-13
Identities = 53/180 (29%), Positives = 89/180 (49%), Gaps = 14/180 (7%)
Query: 127 EESIEDVVMTALENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKF 185
E+S+ V+ A ++G+ FD +EA+ K EA +G +K R I++ TK W
Sbjct: 80 EQSVR-VIRQAFDHGVTFFDTAEAYGPFKSEAIVGEAIKPF---RKQIVLATKYGWDIDQ 135
Query: 186 HTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEG 245
T R+ + H+ V L RLQ +YID++ H+ DP P+EE+ M ++ G
Sbjct: 136 ATGQRTGKVNSKPAHIKRVVDNMLKRLQTDYIDLLYQHRADPEVPVEEIAGTMQELMKAG 195
Query: 246 WVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
++ +G SP I R+ + I PI Q+EY + R + +P + ++G+G
Sbjct: 196 KILGYGLCEVSPQTI-------RKAHAIAPITAVQSEYSLLFRGRENDVLP-VCRELGIG 247
>UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 313
Score = 77.8 bits (183), Expect = 7e-13
Identities = 48/163 (29%), Positives = 87/163 (53%), Gaps = 12/163 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE- 158
+R + LGKS L VP + G + + E +++ + T LE GI FD ++ + KG E
Sbjct: 8 MRRQMLGKSMLEVPVVAAGCMRIQGMDETEVDEYIHTCLELGIQFFDHADIY-GKGACES 66
Query: 159 -LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
GR+ ++ RR II+ +K + S++H+++SV+ SL RL+ +Y+
Sbjct: 67 LFGRVFEQTEFRREDIILQSKCGIVPGVMYD-------FSKEHILQSVEESLRRLRTDYL 119
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
D++LLH+ D + EE+ + + G V ++G + +P +I
Sbjct: 120 DILLLHRPDALMEPEEVAEAFDLLEGSGKVRHFGVSNHTPMQI 162
>UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1;
Leptospirillum sp. Group II UBA|Rep: Putative
oxidoreductase - Leptospirillum sp. Group II UBA
Length = 337
Score = 77.4 bits (182), Expect = 9e-13
Identities = 63/212 (29%), Positives = 106/212 (50%), Gaps = 21/212 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLS-------EESIEDVVMTALENGINLFDLSEAH-CA 153
++ + LG+SGL V +IGLGL M EES+ + + A+E G+ D ++ +
Sbjct: 1 MQKRRLGRSGLSVSSIGLGLMGMSEFYGQSDREESLRTLHL-AIEKGMTFLDTADMYGMG 59
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
+ E LG + R+ RR + I TK + N R ++ + + SL RL
Sbjct: 60 ENEKLLGEAI--RDHRREDLFIATKC-GIQRDPANGRFVGVNGKPDYIKKCCEESLRRLG 116
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+E ID+ LH++DP P+EE M ++ EG + +G + SP++I AY +
Sbjct: 117 IETIDLYYLHRIDPATPVEESASAMAELVREGKIRAYGLSEASPNDIRKAYK-------V 169
Query: 274 TPIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
P+ Q+EY +F R+ EL + ++G+G
Sbjct: 170 YPLAALQSEYSLFTRD-VELEVLGTTRELGIG 200
>UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep:
Oxidoreductase - Hartmannella vermiformis (Amoeba)
Length = 325
Score = 77.0 bits (181), Expect = 1e-12
Identities = 59/195 (30%), Positives = 95/195 (48%), Gaps = 16/195 (8%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM----------LSEESIEDVVMTALENGINLFDLSEAHCA 153
Y LG +GL+V I LG T EE+ ++ E G N D ++ +
Sbjct: 1 YNYLGHTGLKVSEICLGTMTFGASDNYGIPTCDEETSFKLMDRYRELGGNFLDTADVYGP 60
Query: 154 -KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
E +G +KK +VR+ +II TK + T F N + GLSRKH+IE+V++SL L
Sbjct: 61 YNSEKIVGSWIKKNDVRK-EMIIATKGRFETGFGPN----DGGLSRKHIIEAVESSLSNL 115
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
Q +YID+ +H D P+ E + +N ++ G + Y G + +S ++ A +Q
Sbjct: 116 QTDYIDLYQVHLWDAGAPLRETLMTLNDLVRIGKIRYIGCSNFSGWQLQKAIDLSKQMGL 175
Query: 273 ITPIVEQTEYHMFCR 287
Q +Y++ R
Sbjct: 176 EMFASVQQQYNLLDR 190
Score = 37.9 bits (84), Expect = 0.66
Identities = 18/61 (29%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 407 QVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIH 466
Q + P T+ L + +A LN SM+Q+++ W ++ SV ++GA +++Q ++N
Sbjct: 250 QYWAKNPTTW-TVLDKVEQIAKQLNKSMAQVSLRWVMQRPSVGATIIGARNMQQLEDNCA 308
Query: 467 A 467
A
Sbjct: 309 A 309
>UniRef50_Q9S0N9 Cluster: DTDP-4-keto-6-deoxy-L-hexose
2,3-reductase; n=11; Bacteria|Rep:
DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase -
Streptomyces avermitilis
Length = 347
Score = 76.6 bits (180), Expect = 2e-12
Identities = 58/209 (27%), Positives = 103/209 (49%), Gaps = 13/209 (6%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAH---CAKGEA 157
+ LG++ LR+ + LG + + E ++ AL GI LFD + + KG
Sbjct: 22 HTELGRTRLRISRLALGTVNIGGRVEEPEARRLMDHALAQGITLFDTANTYGWRVHKGYT 81
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +GR L R RR +++ TK+ + ++ GLS ++++ + ASL RL+ +
Sbjct: 82 EEVIGRWLADRPARREQVVLATKV----GDPMGSGPNDHGLSVRNIVAACDASLRRLRTD 137
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
+ID+ LH +D +E+ + M+ +I +G V Y G++ ++ +I A R+ N +
Sbjct: 138 WIDLYQLHHIDRRAGWDEVWQAMDLLITQGKVRYVGSSNFAGWDIASAQEAARRRNALGL 197
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
EQ Y++ R EL + GVG
Sbjct: 198 ASEQCVYNLVTRH-AELEVIPAASAYGVG 225
>UniRef50_Q11BF4 Cluster: Twin-arginine translocation pathway signal
precursor; n=42; Bacteria|Rep: Twin-arginine
translocation pathway signal precursor - Mesorhizobium
sp. (strain BNC1)
Length = 385
Score = 76.6 bits (180), Expect = 2e-12
Identities = 59/209 (28%), Positives = 101/209 (48%), Gaps = 21/209 (10%)
Query: 105 KNLGKSGLRVPNIGLGLWTML--------SEESIEDVVMTALENGINLFDLSEAHCAKGE 156
+NLG L V ++GLG+ M S + +++ TA E G+ FD +EA+ G
Sbjct: 53 RNLG--ALEVSSVGLGVQNMARTYQTTIPSRPEMINIIRTAHERGVTFFDTAEAY---GP 107
Query: 157 AELGRILKKRNVR-RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E RIL + R ++IT+K W+ T R H+ +V+ L RL+ +
Sbjct: 108 HECERILGEAIAPFRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGMLERLRTD 167
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
+D++ H+VDP P+E++ + +++EG V++WG + M T R +
Sbjct: 168 RVDLLYQHRVDPEVPIEDVAGAIKDLMDEGKVLHWGLSE------MGLNTLRRAHAALPV 221
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
Q+EY M R PE + + ++G+G
Sbjct: 222 SAVQSEYSMLWR-GPEDEVLSVCEELGIG 249
>UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzyme;
n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Aryl-alcohol dehydrogenase family enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 325
Score = 76.6 bits (180), Expect = 2e-12
Identities = 67/201 (33%), Positives = 102/201 (50%), Gaps = 21/201 (10%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLS-------EESIEDVVMTALENGINLFDLSEAHC-AKGE 156
+NLG GL+V ++GLG M S +ESI + A+ NG++LFD + + E
Sbjct: 4 RNLGSQGLKVSSVGLGCMGMSSTYGRADDKESIASI-RQAVVNGVSLFDTANVYGNGHNE 62
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
LG+ LK + + T + TK+ R + R ++ V+ SL RL EY
Sbjct: 63 KLLGKALKGVDKQVT---VATKVGIQEMQLNQKRINGRP---DYIRSEVEKSLIRLDREY 116
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ LH+VDP P+EE + M+ ++ EG V Y G + S S I A+ Q + IT +
Sbjct: 117 IDLYYLHRVDPDVPIEESIGEMSRLVEEGKVKYIGISEASLSTIKRAH----QTHPITAV 172
Query: 277 VEQTEYHMFCREKPELYMPEL 297
Q+EY ++ R + MP L
Sbjct: 173 --QSEYSLWSRGVEKEIMPYL 191
Score = 40.7 bits (91), Expect = 0.094
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 8/88 (9%)
Query: 404 SKEQVTGEEPRTYGDKL-------RDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGAT 456
SKE V PR GD L + + NL+ L + SQLA+AW L+ S + G+
Sbjct: 218 SKEDVRQYLPRFQGDNLTANQEVFKVIRNLSQKLGMTSSQLALAWLLQKNSNLIAIPGSK 277
Query: 457 SVEQFKENIHALQVYI-KKIFKVCVKSF 483
S++ ENI + + + KI + K F
Sbjct: 278 SIQHINENIASSHIDLDDKIIHILDKIF 305
>UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacifica
SIR-1|Rep: Oxidoreductase - Plesiocystis pacifica SIR-1
Length = 344
Score = 76.6 bits (180), Expect = 2e-12
Identities = 60/222 (27%), Positives = 108/222 (48%), Gaps = 25/222 (11%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFD 146
P + Y+NLG+SGL V + LG T +E + ++ AL+ GIN FD
Sbjct: 2 PTMEYRNLGRSGLEVSTLCLGTMTFGEANENSFMHGVGANEPTSFRIMDKALDAGINFFD 61
Query: 147 LSEAHCAKGEAELGRILKK---RNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIE 203
++ + G E R++ K + RR +++ TK +F G SR+ ++
Sbjct: 62 TADVYGEDGLTE--RVIGKWFTEHKRRDEVVLATKF----RFRMGPGPLGTGASRRRIVR 115
Query: 204 SVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
V+ SL RLQ + ID+ +H D P EE +R ++ ++ G V+Y G + ++ + ++
Sbjct: 116 CVEDSLRRLQTDRIDLYQVHMQDIDTPEEETLRALDDLVRAGKVLYIGASNYAAYRLTES 175
Query: 264 YTNCRQFNCITPIVE-QTEYHMFCRE-KPELYMPELYHKIGV 303
+F+ + V Q +Y + CR+ + EL H++G+
Sbjct: 176 VMR-SEFDRLERYVSLQAQYSLVCRDIERELVPTCRRHELGI 216
>UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 317
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/174 (29%), Positives = 90/174 (51%), Gaps = 13/174 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCA- 153
+ Y GK+ LRV + LG W + S+ES D + A++ GIN D + A+
Sbjct: 4 MEYTEFGKTQLRVSRMCLGTWGIGGAGWDSYSDESRMDAIKAAVDCGINFIDTAPAYNGG 63
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
+ E +G ++ K VR+ +I+ TK +F N + G + K ++ + SL L+
Sbjct: 64 RAEQYIGEVVHKLGVRK-EVILATKC--GNEF-INGKYVRCGSADK-IMRECEESLRNLK 118
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNC 267
+YIDV L+H DP PMEE + +N + +G +++ G + ++ ++ +A C
Sbjct: 119 TDYIDVYLVHWPDPNVPMEETMDALNTLKKQGKILHIGVSNFTKEQMEEAEKYC 172
>UniRef50_Q9HPH9 Cluster: Aryl-alcohol dehydrogenase; n=3;
Halobacteriaceae|Rep: Aryl-alcohol dehydrogenase -
Halobacterium salinarium (Halobacterium halobium)
Length = 324
Score = 75.8 bits (178), Expect = 3e-12
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 17/169 (10%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLWTMLSEESIEDV---------VMTALEN-GINLFDLSEA 150
GL LG++GLRV + G W E D+ ++ A N G D ++
Sbjct: 2 GLDAVPLGRTGLRVTELAFGTWRFGRETDAGDIEVGEQRAHELLDAYANAGGRFIDTADM 61
Query: 151 HCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ + E +G L R+ R +I +K+YW T N R GL+RKH+ SV L
Sbjct: 62 YGGGRAERYIGDWLADRD--RDRYVIASKVYWPTSTAPNGR----GLNRKHLRASVDNIL 115
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPS 258
RL +YID++ +H+ D P + L+R ++ + EG V Y G + + P+
Sbjct: 116 DRLGTDYIDILYIHRWDDATPADALMRTLDGFVREGTVHYLGASTFHPN 164
>UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep:
Aldo/keto reductase - Rhizobium loti (Mesorhizobium
loti)
Length = 334
Score = 75.4 bits (177), Expect = 4e-12
Identities = 69/216 (31%), Positives = 106/216 (49%), Gaps = 27/216 (12%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIED------VVMTALENGINLFDLSEAHCAK- 154
L + LG GL V IGLG M D + A+E G D +E +
Sbjct: 3 LATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGPHT 62
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRK--HVIESVKASLGRL 212
EA LGR LK + R + I TK F N G+ + H+ E V+ASLGRL
Sbjct: 63 NEALLGRALKGK---RDQVTIATKF----GFRIENGKQLSGVDSRPEHIREVVEASLGRL 115
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
++ID++ H+VDP PME++ + ++ EG V ++G SE A N R+ +
Sbjct: 116 ATDHIDLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGL-----SEAGSA--NIRRAHA 168
Query: 273 ITPI-VEQTEYHMFCRE-KPELYMPELYHKIGVGKI 306
+ P+ Q+EY ++ R +PE+ +P L ++G+G +
Sbjct: 169 VFPVSALQSEYSLWERNLEPEI-IP-LLKELGIGLV 202
>UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus
radiotolerans SRS30216|Rep: Aldo/keto reductase -
Kineococcus radiotolerans SRS30216
Length = 344
Score = 75.4 bits (177), Expect = 4e-12
Identities = 61/210 (29%), Positives = 107/210 (50%), Gaps = 19/210 (9%)
Query: 104 YKNLGKSGLRVPN--IG---LGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
Y+ LG++G+ V +G LG W E +V AL+ GIN D ++ + A GE+E
Sbjct: 3 YRTLGRTGVSVSTTCLGAMMLGPWGNPDPEEGVAIVQQALDAGINFIDTADVYSA-GESE 61
Query: 159 LGRILKKRNV--RRTSIIITTKIYWSTKFHTNNRSD--ERGLSRKHVIESVKASLGRLQV 214
RI+ K RR ++++ +TKFH D +RG SR+ ++ +V+ SL RL
Sbjct: 62 --RIVGKALAGGRRENVVL------ATKFHNAMGQDRNQRGNSRRWIMTAVEDSLRRLGT 113
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
++ID+ +H+ +EE + ++ ++++G V Y G+ + S+I++A R +
Sbjct: 114 DWIDLYQVHRPSTEVDVEETLAALSDLVHQGKVRYVGSTTFPASQIVEAQWVARDRHLQR 173
Query: 275 PIVEQTEYHMFCREKPELYMP-ELYHKIGV 303
+ EQ Y + R +P H +GV
Sbjct: 174 FVTEQPSYSLLTRGAENDVLPTAARHGMGV 203
>UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2;
Arthrobacter|Rep: Aldo/keto reductase - Arthrobacter sp.
(strain FB24)
Length = 357
Score = 75.4 bits (177), Expect = 4e-12
Identities = 50/181 (27%), Positives = 98/181 (54%), Gaps = 12/181 (6%)
Query: 126 SEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWST 183
++ESI ++ AL+ GI D ++ + ++G++E +GR LK R R + I TK +
Sbjct: 49 ADESIR-IINAALDAGITAVDTADVY-SQGQSEQVVGRALKGR---RDDVFIATKFHGQM 103
Query: 184 KFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVIN 243
+ + G SR+ ++++V+ SL RLQ + ID+ H+ D + E + +N +I
Sbjct: 104 SANPAHS----GNSRRWIMQAVEGSLRRLQTDRIDLYQAHRPDYNTDVLETITALNDLIR 159
Query: 244 EGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
+G ++Y+GT+ ++P+++++A + I P+ Q Y M R +P + + G+
Sbjct: 160 QGKILYYGTSVFTPAQLVEAQWLATTNHLIPPVANQVPYSMLVRGTERDVLP-IAQQYGL 218
Query: 304 G 304
G
Sbjct: 219 G 219
>UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga
mobilis SJ95|Rep: Aldo/keto reductase - Petrotoga
mobilis SJ95
Length = 311
Score = 74.9 bits (176), Expect = 5e-12
Identities = 46/169 (27%), Positives = 87/169 (51%), Gaps = 18/169 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM------LSEESIEDVVMTALENGINLFDLSEAHCAKG 155
+R+K GK+ + V +G G W + + +E+ ++ A +NG+N FD + A+ +G
Sbjct: 1 MRFKKFGKTDMSVSVVGYGAWELGGNWGPIEKENGVKILNLAYDNGVNFFDTAPAY-GRG 59
Query: 156 EAE--LGRILKKRNVRRTSIIITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
++E +G LK + +R + I TK + W K N L ++ V++ + SL R
Sbjct: 60 QSEEIVGEFLKGK--KREDLYIATKCGLEWDQKGRIRNN-----LKKERVLKEIDDSLKR 112
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
L+ +Y+D+ +H DP P+EE + +++ Y G + +S +I
Sbjct: 113 LKCDYVDLYQIHWPDPNTPLEETAEAIQQILDSKKARYIGVSNFSAQQI 161
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/50 (32%), Positives = 30/50 (60%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHA 467
+K+ +L LAN + S+SQ+A+ W ++ V+ ++ G+ + ENI A
Sbjct: 243 EKVEELKILANKIGRSLSQMAINWLSHHKQVSTVIAGSKDEKHVLENIEA 292
>UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2
family; n=1; Enterococcus faecalis|Rep: Oxidoreductase,
aldo/keto reductase 2 family - Enterococcus faecalis
(Streptococcus faecalis)
Length = 303
Score = 74.5 bits (175), Expect = 6e-12
Identities = 47/161 (29%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE--L 159
++ G S V ++ LG + E+ + V+ TA ++GI FD ++ + G+ E
Sbjct: 1 MKQLQFGTSDETVSSVILGCMRLNGAENPQQVIETAYDHGITFFDHADIY-GGGDCETIF 59
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G+ LK+ +RR I I TK F S+ H++E+V+ SL RL V+ +D
Sbjct: 60 GKALKESTIRREDIFIQTKCGIRQGFFD--------FSKAHILEAVEGSLQRLGVDSVDA 111
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
+LLH+ D + EE+ + + +G V Y+G + +P +I
Sbjct: 112 LLLHRPDTLVEPEEVAEAFHLLEKQGKVRYFGVSNQTPGQI 152
>UniRef50_Q1YGH2 Cluster: Putative aldo/keto reductase; n=1;
Aurantimonas sp. SI85-9A1|Rep: Putative aldo/keto
reductase - Aurantimonas sp. SI85-9A1
Length = 336
Score = 74.1 bits (174), Expect = 8e-12
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 8/162 (4%)
Query: 139 ENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS 197
E G N D ++++ K EA LGR+LK+R R ++ TK+ + GLS
Sbjct: 44 EVGGNFIDTADSYTGGKSEAMLGRLLKER---RADCVLATKV----GNPVTDVEGSGGLS 96
Query: 198 RKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
+ + + S RLQ E ID+ LH D P++E++ + +I +G + +WG + +
Sbjct: 97 PAWIARAAEMSRERLQTETIDLYYLHLDDETTPLDEVIGALGELIAKGTIRHWGFSNFRG 156
Query: 258 SEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYH 299
+I D + P+V Q YHM R Y+P +H
Sbjct: 157 WKIADMVRIADRLGVARPVVAQPYYHMLNRTAEPDYLPACHH 198
>UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Aldo/keto reductase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 343
Score = 74.1 bits (174), Expect = 8e-12
Identities = 55/210 (26%), Positives = 107/210 (50%), Gaps = 23/210 (10%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLS------EESIEDVVMTALENGINLFDLSEAHCAK-GEA 157
+ LG G V IGLG + + E+ +D+V A++ G+ LFD ++ + + E
Sbjct: 11 RRLGSGGPEVSAIGLGFMSFRAGSGPDDEKQAKDIVDAAIDLGVTLFDTADIYGPEHSEV 70
Query: 158 ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRK--HVIESVKASLGRLQVE 215
LG+ ++ R R S++I TK + + +D R L + +V +++ SL RL V+
Sbjct: 71 LLGKAIRGR---RDSLVIATK--FGNRLDRGTSTDGRALDGRPEYVRSAIEGSLRRLGVD 125
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
++D+ H+VDP P+E+ V + ++ G V + G + P + R+ + + P
Sbjct: 126 HVDLYYQHRVDPQVPIEDTVGALAELVQAGKVRHIGLSEPGPQTL-------RRAHAVHP 178
Query: 276 IVE-QTEYHMFCREKPELYMPELYHKIGVG 304
+ Q E+ +F R+ + +P + ++G+G
Sbjct: 179 VAAIQNEWSLFTRDIEDETVP-IARELGIG 207
>UniRef50_A6VL42 Cluster: Aldo/keto reductase; n=3;
Pasteurellaceae|Rep: Aldo/keto reductase -
Actinobacillus succinogenes 130Z
Length = 299
Score = 73.7 bits (173), Expect = 1e-11
Identities = 46/156 (29%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 120 GLWTMLSEESIEDVVMT----ALENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSII 174
G W + S + ++T LE GI+ FD + + + EAELGR L R+ +
Sbjct: 18 GFWRLKSWQKSPQELLTFIKQGLEFGIDTFDHAACYGSFTAEAELGRALALDKSLRSQLT 77
Query: 175 ITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPME 232
+ TK I + + +S S +H+I S + S+ +LQ EY+DV+L+H++ P E
Sbjct: 78 LVTKCGILYPNDELSQIKSHHYDNSYRHIIWSAQRSIEKLQCEYLDVLLIHRLSPCADPE 137
Query: 233 ELVRVMNYVINEGWVMYWGTARWSPSE--IMDAYTN 266
++ R N + G V Y+G + ++P++ ++ +Y N
Sbjct: 138 QIARAFNELHQSGKVRYFGVSNYTPAKFSMLQSYVN 173
>UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: MocA - Stigmatella aurantiaca DW4/3-1
Length = 341
Score = 73.3 bits (172), Expect = 1e-11
Identities = 54/219 (24%), Positives = 105/219 (47%), Gaps = 23/219 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------------LSEESIEDVVMTALENGINLFDLS 148
+ Y+ LG SGL+V ++ LG T E++ ++ AL+ GIN +D +
Sbjct: 1 MEYRKLGHSGLKVSSLCLGTMTFGEPSEGSTMHGVACDEKTAFSIMDRALDAGINFWDTA 60
Query: 149 EAHCAKGEAELGRILKK---RNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESV 205
+ G E R+L + RR +++ TK +F ++ G SR + +V
Sbjct: 61 NVYGNDGLTE--RVLGNWFAHSQRRDEVVLATKF----RFRMGKGPNDTGASRYQIRSAV 114
Query: 206 KASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYT 265
+ SL RL+ + ID+ +H D P EE +R ++ ++++G V+Y G + ++ ++D+
Sbjct: 115 EQSLRRLKTDRIDLYQVHMQDIDTPEEETLRALDDLVHQGKVLYLGASNYAAYRLVDSLW 174
Query: 266 NCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ N + Q +Y + R+ + P + + G+G
Sbjct: 175 TSKSQNLSRFVALQAQYSLVVRDLEREHTP-VCEQFGLG 212
>UniRef50_Q75ZG2 Cluster: Aldo-keto reductase; n=10;
Pezizomycotina|Rep: Aldo-keto reductase - Alternaria
alternata (Alternaria rot fungus)
Length = 367
Score = 72.9 bits (171), Expect = 2e-11
Identities = 69/233 (29%), Positives = 107/233 (45%), Gaps = 32/233 (13%)
Query: 104 YKNLGKSGLRVPN-------IGLGLWT--MLSEESIEDVVMTALENGINLFDLSEAHCAK 154
Y+ LG SGL V N IG W +L E+ ++ A + GIN +D + + +
Sbjct: 25 YRRLGNSGLLVSNPILGGMHIGDPRWYDWVLDEKDSIALLKAAYDRGINTWDTANIY-SN 83
Query: 155 GEAE--LGRILKKRNVRRTSIIITTKIYW-------------STKFH---TNNRSD---E 193
GE+E +GR L+ N+ R+ ++I TK + ST F T D
Sbjct: 84 GESERIMGRALRSHNIPRSKVVIMTKCFRAVTDPDVDGDIGSSTAFFPDLTRQSKDYVNH 143
Query: 194 RGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
GLSR V + V+ASL RL +YIDV+ +H+ D P EE ++ ++ ++ V Y G +
Sbjct: 144 CGLSRASVFQQVEASLRRLNTDYIDVLHIHRFDHHVPPEETMKALHDLVQMNKVRYLGAS 203
Query: 254 RWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
E + N + Q Y++ RE+ E M + + GVG I
Sbjct: 204 SMWAHEFAILQHTAEKNNWTKFVSMQNHYNLLYREE-EREMIKYCNLTGVGLI 255
>UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria
monocytogenes|Rep: Lmo0084 protein - Listeria
monocytogenes
Length = 327
Score = 72.5 bits (170), Expect = 3e-11
Identities = 59/214 (27%), Positives = 103/214 (48%), Gaps = 24/214 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAK 154
++ + LG +GL +G G + + +VV TA++ GI +FD +E +
Sbjct: 1 MKKRQLGNAGLVTSELGFGCMGLNYHRGPAKDRNEMIEVVRTAMDAGITMFDTAEVYGPY 60
Query: 155 GEAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
EL G L + R + I TK + NN D R S K +E SL RL+
Sbjct: 61 TNEELVGEALVGK---RNHVQIATKGGFKIN-GLNNEVDSRPESIKAAVEG---SLKRLK 113
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+YID+ +H++DP P+EE+ + + EG +++WG + S I R+ + +
Sbjct: 114 TDYIDLYYIHRIDPSIPIEEVAGTIQNLKQEGKILHWGLSEASAKTI-------RRAHKV 166
Query: 274 TPIVE-QTEYHMFCREKPELYMPELYHKIGVGKI 306
P+ ++EY ++ RE + P L ++G+G +
Sbjct: 167 EPLAAVESEYSIWWREAEKEVFPVL-EELGIGLV 199
>UniRef50_Q64UL3 Cluster: Aldo/keto reductase family oxidoreductase;
n=8; Bacteria|Rep: Aldo/keto reductase family
oxidoreductase - Bacteroides fragilis
Length = 333
Score = 72.5 bits (170), Expect = 3e-11
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIED------VVMTALENGINLFDLSEAHCAKG 155
++Y+ LGK+ + + IGLG M + + D + ALE GIN +D ++ +
Sbjct: 1 MKYRKLGKTEVNLSAIGLGCMGMSAAYGVADEKESIKTLHRALELGINFWDTADVYGNGA 60
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNN----RSDERGLSRKHVIESVKASLGR 211
EL + K +R I I TK + + + S ++V ++V+ SL R
Sbjct: 61 NEEL--LSKVLAEKRNQIFIATKFGFRLRNSQGSVFAGGESYVDASPRYVKQAVENSLKR 118
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
L +E ID+ H++DP P+EE V M ++ EG V Y G + SP + A
Sbjct: 119 LNIETIDLYYAHRIDPTIPIEETVEAMAELVKEGKVRYLGLSECSPKSLKRA 170
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 72.5 bits (170), Expect = 3e-11
Identities = 56/198 (28%), Positives = 105/198 (53%), Gaps = 30/198 (15%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIE--------DVVMTALENGINLFDLSEAHCA 153
+ +KNL + +++P IGLG WT+ + + + TA++ GI D +EA+ A
Sbjct: 1 MEFKNLSNN-IKIPVIGLGTWTIGGGDEADTTYDKENISAIKTAIKLGITHIDNAEAY-A 58
Query: 154 KGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
+G +E +GR + + R S+ IT+K+ S E LS +++ S K SL R
Sbjct: 59 QGHSEELVGRAIV--GLDRKSLFITSKV-----------SPEH-LSYDNLLASAKGSLQR 104
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
L +YID+ L+H +P P++E ++ M++++ + V G + +S +I +A +++
Sbjct: 105 LNTDYIDLYLIHAPNPDIPIQETMKAMDFLVEQKLVRCIGVSNFSVDQIKEA----QKYT 160
Query: 272 CITPIVEQTEYHMFCREK 289
+ Q EY++ R+K
Sbjct: 161 KNKIVANQIEYNLLVRDK 178
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 72.5 bits (170), Expect = 3e-11
Identities = 50/176 (28%), Positives = 83/176 (47%), Gaps = 19/176 (10%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G +P +G G W + E++ V TAL+ G D ++ + EA +G K+ V+
Sbjct: 8 NGADIPKLGFGTWQLEDEDAARGVA-TALKTGYRHIDTAQIY--GNEAAVGDGWKQSGVK 64
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R +TTK+ W KF + SVK SL +L+ +Y+D++LLH P
Sbjct: 65 REDFFLTTKV-WRDKFRDGDLQ-----------ASVKESLDKLKTDYVDLLLLHWPVPEV 112
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMF 285
P+ E ++ MN V G V + G + ++ +D R + + Q EYH +
Sbjct: 113 PIAETMKAMNEVKEAGQVRHIGVSNFT----VDLLDEARAHSGAPLVANQVEYHPY 164
>UniRef50_Q2S286 Cluster: Oxidoreductase, aldo/keto reductase
family; n=1; Salinibacter ruber DSM 13855|Rep:
Oxidoreductase, aldo/keto reductase family -
Salinibacter ruber (strain DSM 13855)
Length = 333
Score = 72.1 bits (169), Expect = 3e-11
Identities = 48/168 (28%), Positives = 86/168 (51%), Gaps = 13/168 (7%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAH-CAKG 155
P RY LG +G++V + LG T + + E GIN+FD + + +
Sbjct: 4 PSPRY--LGDTGVKVSPLCLGTMTFGGPADRATAAAMFRRCREAGINVFDCANVYEDGRS 61
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E LG ++ R +++TTK Y F + + RG SR H++ +V+ SL RL +
Sbjct: 62 EEILGELVADC---RDEVVLTTKAY----FPVGDDPNARGASRYHLVRAVEDSLRRLDTD 114
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
IDV +H+ D ++E +R ++ ++ +G V+Y G + ++ ++M A
Sbjct: 115 RIDVFFVHRFDEQTRLDETLRALDTLVQQGKVLYLGASNFAAWQVMKA 162
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 72.1 bits (169), Expect = 3e-11
Identities = 46/176 (26%), Positives = 87/176 (49%), Gaps = 17/176 (9%)
Query: 114 VPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSI 173
+P +GLG W ++ I DVV L G D ++A+ E E+G+ +K+ V R
Sbjct: 16 IPVLGLGTWQSTGQDCI-DVVSQGLRMGYEHIDTAQAY--GNEVEVGKGIKQSGVARDKF 72
Query: 174 IITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEE 233
+TTKI+ D+ + ++ + K SL L +Y+D++LLH D P+ E
Sbjct: 73 FLTTKIF----------PDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPDDRVPLSE 122
Query: 234 LVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ + + +G G + ++ + I++A +++ + +V Q E+H F ++K
Sbjct: 123 TIPALCELQKQGLTRNIGVSNFNIANIIEA----KRYADVPIVVNQVEFHPFIKQK 174
>UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2;
Desulfurococcales|Rep: Universally conserved protein -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 336
Score = 71.7 bits (168), Expect = 4e-11
Identities = 66/212 (31%), Positives = 102/212 (48%), Gaps = 27/212 (12%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLWTMLSE----ESIEDVVMTA---LENGINLFDLSEAHCA 153
GL Y LG+SGLRV +GLGLW S S+ DVV A LE G+NLFD +E + A
Sbjct: 5 GLLYVVLGRSGLRVSRVGLGLWQAGSRLWGGVSLGDVVAAAERGLELGLNLFDTAELYGA 64
Query: 154 -KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
+ EA LG L++ R +++ TK+ R G+ + +E + LGR
Sbjct: 65 GRSEALLGEALRRAGA-RDGVVVVTKV-------AGYRVTWAGV--RKALEGSRRRLGRS 114
Query: 213 QVEYIDVVLLHKVDPV-CPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
D+VL H PV + +VR++ ++EG Y G + ++ E+ +A R+
Sbjct: 115 P----DIVLYHWPPPVPFTVCRVVRLLERAVDEGLAAYMGVSNFNARELEEAVQCTRRHE 170
Query: 272 CITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
+V+Q Y + PE + ++GV
Sbjct: 171 I---VVDQVHYSI-AHRVPENRLIPTARRLGV 198
>UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Aldo/keto reductase -
Stigmatella aurantiaca DW4/3-1
Length = 330
Score = 71.3 bits (167), Expect = 6e-11
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 11/165 (6%)
Query: 133 VVMTALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNR 190
+V ALE GI FD + A+ GE+E LG+ L+ R R + I TK ++ +
Sbjct: 44 IVHRALERGILFFDTANAY-GNGESERILGQALRGR---RAQVGIATKAGFARV-----Q 94
Query: 191 SDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYW 250
GLS V +++ SL RL +++D+ LH+ DP P+EE + + ++ G +W
Sbjct: 95 GKPEGLSAPVVERALEQSLERLGTDHVDLFYLHQPDPATPIEETLGAVERLLRAGKARHW 154
Query: 251 GTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMP 295
G + ++ ++++ T C P V Q Y++ R+ Y+P
Sbjct: 155 GVSNFAAWQLLELDTLCDARGMPRPAVSQVLYNLVVRQIEMEYLP 199
>UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomyces
viridochromogenes|Rep: Putative oxidoreductase -
Streptomyces viridochromogenes
Length = 330
Score = 70.9 bits (166), Expect = 8e-11
Identities = 57/201 (28%), Positives = 95/201 (47%), Gaps = 17/201 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLS-----EESIEDVVMTALENGINLFDLSEAHCA-KG 155
+RY+ LG+ G V ++ LG W + E + V A + G+N FD + A+ A
Sbjct: 1 MRYRTLGRQGPEVSSVCLGTWALSGFWGSRTEPAVEAVRRAFDLGVNFFDTAHAYGAGMA 60
Query: 156 EAELGRILKKR-NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
EA L R L RR+ I+I+TK + R+ + G R ++ +S++ SLG
Sbjct: 61 EAGLARGLGDLLRTRRSDIVISTKGGLELRGDGVVRNSDAGFLRANLTDSLR-SLG---T 116
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+Y+DV L+H DP P E + + EG Y G + ++ E+ + + +T
Sbjct: 117 DYVDVFLVHWPDPRVPPAETAGALAGFVEEGLARYVGVSNFTVEEMAEF------SSVVT 170
Query: 275 PIVEQTEYHMFCREKPELYMP 295
P V Q ++M R + +P
Sbjct: 171 PQVAQVPFNMLDRGIEKQVLP 191
>UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzyme;
n=3; Firmicutes|Rep: Aryl-alcohol dehydrogenase related
enzyme - Pediococcus pentosaceus (strain ATCC 25745 /
183-1w)
Length = 340
Score = 70.9 bits (166), Expect = 8e-11
Identities = 50/165 (30%), Positives = 85/165 (51%), Gaps = 25/165 (15%)
Query: 102 LRYKNLGKSGLRVPNIGLGL-----------WTMLSEESIEDVVMTALENGINLFDLSEA 150
++Y LGK+ + V I +G WT+ ES E V+ AL GIN FD +
Sbjct: 6 MQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPES-EKVIRHALNLGINFFDTANV 64
Query: 151 HCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKAS 208
+ +KG +E LGR LK+ N+ R ++I +K+Y++ E LS+ + + +
Sbjct: 65 Y-SKGTSEEFLGRALKENNIARDQVVIASKVYFN----------EGRLSKDAINREIDGT 113
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
L RL +Y+D+ ++H+ D P+EE + +N ++ G V G +
Sbjct: 114 LRRLGTDYLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGAS 158
>UniRef50_A1WAL7 Cluster: Aldo/keto reductase; n=35; cellular
organisms|Rep: Aldo/keto reductase - Acidovorax sp.
(strain JS42)
Length = 354
Score = 70.9 bits (166), Expect = 8e-11
Identities = 55/208 (26%), Positives = 101/208 (48%), Gaps = 14/208 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
++Y+ LGKS L+V + LG + +V A +G+N D ++ + KG +E
Sbjct: 22 MQYRFLGKSQLQVSTLCLGTMMFGDQTDKAEAASIVAHARAHGVNYMDTADVY-TKGASE 80
Query: 159 --LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
LG +L+ + R ++ TK+ K + R +E SR ++ V+ASL RLQ ++
Sbjct: 81 RMLGTLLQGQ---RHDWVLATKL--GNKM--SERPNEGRYSRAWMLREVEASLTRLQTDH 133
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+D++ LH+ +EE + ++ ++ G + YWG + + I + R+ P+
Sbjct: 134 VDILYLHRDYEGMDLEEPLFAIDALLRAGKIRYWGVSNFRGWRIAELVHGARRIGMPGPV 193
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVG 304
V Q Y++ R +P H G+G
Sbjct: 194 VCQPYYNLLNRMPEVEILPACQH-YGLG 220
>UniRef50_Q747Y9 Cluster: Oxidoreductase, aldo/keto reductase
family; n=28; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Geobacter sulfurreducens
Length = 334
Score = 70.5 bits (165), Expect = 1e-10
Identities = 61/212 (28%), Positives = 101/212 (47%), Gaps = 23/212 (10%)
Query: 107 LGKSGLRVPNIGLGLWTML-------SEESIEDVVMTALENGINLFDLSEAHCAKGEAEL 159
LGKSGL V +GLG M E + ++ TA+E GI FD +E + EL
Sbjct: 6 LGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPFINEEL 65
Query: 160 -GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGL--SR-KHVIESVKASLGRLQVE 215
G L R ++I TK + T + + SR +H+ +ASL RL+ +
Sbjct: 66 VGEALAPLRER---VVIATKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLRTD 122
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
ID+ H+VDP P+EE+ + +I EG V ++G + + R+ + + P
Sbjct: 123 VIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLSEAGIETV-------RRAHAVQP 175
Query: 276 IV-EQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ Q EY ++ R +PE + + ++G+G +
Sbjct: 176 VACVQNEYSLWFR-RPEEGLLQALEELGIGLV 206
>UniRef50_A0QHX8 Cluster: General stress protein 69; n=2;
Mycobacterium avium|Rep: General stress protein 69 -
Mycobacterium avium (strain 104)
Length = 328
Score = 70.5 bits (165), Expect = 1e-10
Identities = 56/206 (27%), Positives = 98/206 (47%), Gaps = 21/206 (10%)
Query: 108 GKSGLRVPNIGLGLWTMLSE--ESIEDVVMTALEN----GINLFDLSEAH-CAKGEAELG 160
GK+GL V + G W S+ + ED +T + + GIN FD ++ + E LG
Sbjct: 7 GKTGLEVSRLAFGTWEFCSDWGHADEDAAITMIRSARDLGINFFDTAQQYGFGASERLLG 66
Query: 161 RILKKRNVR-RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
+ L+ R R ++I TK + R S + + + V++SL L +++IDV
Sbjct: 67 KALRDDLARARDEVVIATK----GGLRATDSGLVRDASPQWLRKGVESSLTALGIDHIDV 122
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI-VE 278
L+H DP P E + +++EG + + G + + +++ +F+ P+ V
Sbjct: 123 YLVHWPDPRMPAAETAGALAELVSEGKIRHVGVSNYDTAQV-------EEFSATLPVEVV 175
Query: 279 QTEYHMFCREKPELYMP-ELYHKIGV 303
Q YH+F R+ + +P H IGV
Sbjct: 176 QPPYHLFRRDIEDTLLPYAREHDIGV 201
>UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Frankia
alni ACN14a|Rep: Putative aldoketoreductase - Frankia
alni (strain ACN14a)
Length = 336
Score = 70.1 bits (164), Expect = 1e-10
Identities = 52/193 (26%), Positives = 93/193 (48%), Gaps = 17/193 (8%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLS-------EESIEDVVMTALENGINLFDLSEAHCA-KG 155
Y+ +G+SGL+V LG S E ++ L+ G N+ D ++ + +
Sbjct: 3 YRTMGRSGLKVSQACLGAMNFGSVGLGSCDETEATRIINAFLDAGHNVIDTADIYSGGQS 62
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +GR + + RR +++ TK + N R G SR H+ ++ ASL RL +
Sbjct: 63 EQIVGRAI---SARRDEVVLATKGHMPAGPGPNGR----GSSRVHLTRALDASLSRLGTD 115
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ +H+ D P+EE + ++ + G V Y G + ++ S I++A + + TP
Sbjct: 116 YVDLYQVHQPDDETPIEETMATLDGFVRAGKVRYLGCSNYNASRIVEAQWAAERIHG-TP 174
Query: 276 IVE-QTEYHMFCR 287
V Q +Y + R
Sbjct: 175 FVSLQPQYSLVAR 187
>UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3;
Desulfurococcales|Rep: Aldo/keto reductase -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 272
Score = 70.1 bits (164), Expect = 1e-10
Identities = 56/192 (29%), Positives = 93/192 (48%), Gaps = 17/192 (8%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCA-KGEAELGRIL 163
K +GK+G V IGLG W + + + A+ENGI+ D +E + K E +GR++
Sbjct: 12 KPIGKTGETVTAIGLGTWAIRDYSKAYNAFVYAIENGIDNIDTAEMYDGGKAEEFVGRVV 71
Query: 164 KKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
R V + + +TTK+ H SDE V+++ KASL RL + +D+ L+H
Sbjct: 72 --RAVGKDKVFVTTKMLP----HHLVSSDE-------VLKAAKASLKRLGLSEVDLFLIH 118
Query: 224 KVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYH 283
+ +EE VR V EG Y G + ++ E+ A R+ +V+Q Y
Sbjct: 119 WPNESLTIEEQVRNFEIVYEEGLARYIGVSNFNVYELEKAIHATRKAEI---VVDQVHYS 175
Query: 284 MFCREKPELYMP 295
+ ++ + +P
Sbjct: 176 VLTKDIEKDLLP 187
>UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep:
Oxidoreductase - Stigmatella aurantiaca DW4/3-1
Length = 331
Score = 69.7 bits (163), Expect = 2e-10
Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 8/169 (4%)
Query: 138 LENGINLFDLSEAHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGL 196
L G N FD ++ + EA LG+ + + VR +++TTK + +F N G
Sbjct: 10 LAAGGNFFDTADFYTQGTSEAMLGKFVAEAGVR-DRVVLTTKFSNNVEFGNPNAG---GN 65
Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
RK ++ +V+ASL RL+ +YID+ LLH D + P EE++R + ++ G + Y G +
Sbjct: 66 GRKSMMRAVEASLRRLRTDYIDLYLLHTWDRITPAEEVMRTFDDLVRAGKIRYAGLSD-V 124
Query: 257 PSEIMDAYTNCRQFNCITPIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
P + + +TP++ Q +Y + R ++P L +G+G
Sbjct: 125 PGWYAGRAQTYAEAHALTPLINLQLQYSLIERNIEPEFVP-LAQTLGLG 172
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 69.7 bits (163), Expect = 2e-10
Identities = 61/196 (31%), Positives = 97/196 (49%), Gaps = 30/196 (15%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINL----FDLSEAHCAKG 155
+K+L K+G +P +G G W M + + +D + A+ GI D +E + A G
Sbjct: 6 WKSL-KNGFAIPVLGQGTWRMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMY-AGG 63
Query: 156 EAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
AE +G +K + +RR +T K+ W T R D+ V+ + +ASL RL
Sbjct: 64 HAEELVGIAMKGQGIRRADYFLTDKV-WKTHL----RYDD-------VLRAAEASLKRLG 111
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
+YID+ L+H+V+P P EE +R MN + EG + + G + +S + A Q
Sbjct: 112 TDYIDLYLIHQVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRA-----QAASD 166
Query: 274 TPIV-EQTEYHMFCRE 288
PIV Q Y++ RE
Sbjct: 167 APIVANQLHYNLRIRE 182
>UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Silicibacter sp. (strain TM1040)
Length = 331
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/215 (27%), Positives = 99/215 (46%), Gaps = 27/215 (12%)
Query: 105 KNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
+ +G+SG+ IGLG W + E + ++E G++L D + A+ +G A
Sbjct: 8 REIGRSGIEASAIGLGTWAIGGWMWGGTDEARSIAAIQASIEAGVSLIDTAPAY-GQGVA 66
Query: 158 E--LGRILKKRNVRRTSIIITTK--IYWSTK-----FHTNNRSDERGLSRKHVIESVKAS 208
E +G+ +K R R +++ TK + W T+ F + R L + +I V+ S
Sbjct: 67 EEIVGKAIKDR---RDKVVLATKCGLVWHTQKGNHFFDYDGAPVHRYLGKDAIIYEVEQS 123
Query: 209 LGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCR 268
L RL +YID + H DP P+ E + + + +G + G + +P ++ AY
Sbjct: 124 LTRLGTDYIDHYITHWQDPTTPIAETMEALEQLKTQGKIRSIGASNTTPLDVR-AYLEAG 182
Query: 269 QFNCITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
Q + + Q EY M R E M L H+ GV
Sbjct: 183 QLDAV-----QEEYSMVNR-AVEAEMAPLCHENGV 211
>UniRef50_Q7NFR4 Cluster: Gll3460 protein; n=5; Bacteria|Rep:
Gll3460 protein - Gloeobacter violaceus
Length = 367
Score = 68.5 bits (160), Expect = 4e-10
Identities = 62/213 (29%), Positives = 104/213 (48%), Gaps = 19/213 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGL--------WTMLSEESIEDVVMTALENGINLFDLSEAHC- 152
+RYK LG+SGLRV + LG W SEES + + A G N D + A+
Sbjct: 9 MRYKLLGRSGLRVSELCLGTMTFGDEWGWGGSSEESRKMFDIFANVGG-NFIDTANAYTN 67
Query: 153 AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
E +G + R ++ TK +T+ N G +RK +++ ++ SL RL
Sbjct: 68 GTSEKLVGEFIAPE---RDRFVVATKYTANTRPGDPNAG---GNARKSLVQGIEGSLKRL 121
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
EYID++ +H D + P+EE++R ++ + +G V+Y G + +P+ I+ Q
Sbjct: 122 GTEYIDLLWVHAWDFMTPIEEVMRSLDDAVRQGKVLYIGISD-TPAWIVSRANTLAQCYG 180
Query: 273 ITPIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
TP + Q EY + R PE + + + + +G
Sbjct: 181 WTPFIGLQIEYSLIER-TPERDLVPMANALELG 212
>UniRef50_Q0LP92 Cluster: Aldo/keto reductase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Aldo/keto reductase -
Herpetosiphon aurantiacus ATCC 23779
Length = 326
Score = 68.5 bits (160), Expect = 4e-10
Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Query: 122 WTMLSEESIEDVVMTALENGINLFDLSEAHC-AKGEAELGRILKKRNVRRTSIIITTKIY 180
WT E + ALE I LFD ++ + K E G +L ++ R I++ +K
Sbjct: 35 WTSSEYEIGRKALAAALEQSITLFDHADIYTRGKSERLFGELLAEQPSLRQQIVLQSKCG 94
Query: 181 WSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNY 240
S +H+I SV+ SL RL +++D++LLH+ D + EE+ + +
Sbjct: 95 IRFADEPPGSPQRYDFSYEHIITSVEGSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQ 154
Query: 241 VINEGWVMYWGTARWSPSEI 260
+ G V Y+G + SP++I
Sbjct: 155 LQQSGKVRYFGVSNHSPAQI 174
>UniRef50_A3US12 Cluster: Oxidoreductase, aldo/keto reductase
family; n=11; Proteobacteria|Rep: Oxidoreductase,
aldo/keto reductase family - Vibrio splendidus 12B01
Length = 336
Score = 68.5 bits (160), Expect = 4e-10
Identities = 40/129 (31%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
Query: 133 VVMTALENGINLFDLSEAHC-AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRS 191
V+ T+LE+GINLFD ++ + +K E G+ L++ R + I +K +F
Sbjct: 56 VIDTSLESGINLFDHADIYTFSKAEQAFGQALQQAPELREQMFIQSKC--GIRFEGEGNV 113
Query: 192 DERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG 251
S V +SV + L RL E +DV+LLH+ DP+ ++EL R + ++ +G V ++G
Sbjct: 114 GRYDFSADWVSQSVDSILNRLNTEKLDVLLLHRPDPLMELDELARALEHLKAQGKVDFFG 173
Query: 252 TARWSPSEI 260
+ + +I
Sbjct: 174 VSNMNSHQI 182
>UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular
organisms|Rep: Aldo/keto reductase - Bacillus coagulans
36D1
Length = 329
Score = 68.5 bits (160), Expect = 4e-10
Identities = 45/169 (26%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDV--VMTALENGINLFDLSEAH-CAKGEAELGRILKKR 166
SG+ + +G W + +E + + A++ GIN+ D + A+ + E +G+ L +
Sbjct: 15 SGVALGTWAIGGWMWGGTDEMESIKTIQAAIDLGINVIDTAPAYGFGRSEEIVGKALAEV 74
Query: 167 NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVD 226
+R ++I+TK+ K N R S++ ++ + SL RLQ +YID+ +H D
Sbjct: 75 G-QRDKVVISTKVALEWK----NGEVFRNGSKERILAEIDDSLKRLQTDYIDIYQVHWPD 129
Query: 227 PVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
P P+EE M + + G + G + +SP E M+A+ + + P
Sbjct: 130 PKVPIEETAEAMKTLYDSGKIRAIGVSNFSP-EQMEAFRTVAPLHTVQP 177
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 68.5 bits (160), Expect = 4e-10
Identities = 51/190 (26%), Positives = 97/190 (51%), Gaps = 22/190 (11%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLWTMLSEESIEDV--VMTALENGINLFDLSEAHCAKGEAE 158
G++ +G +V IG+G W++ S E+V + AL++G+N D +E + E
Sbjct: 3 GMQTAEFDGTGRKVSVIGVGTWSLEGSRS-ENVRSIRYALDHGVNFIDTAEMYGT--EDI 59
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
+G +K RR + I TK+ W T F ++ V++S + SL +L +Y+D
Sbjct: 60 VGEAIK--GYRREDLFIATKV-WPTHFAYHD-----------VLKSCEESLKKLGTDYVD 105
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
+ LH +P ++E + M +++EG + Y G + +S E+ +A + ++ ++
Sbjct: 106 LYQLHWPNPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVS---N 162
Query: 279 QTEYHMFCRE 288
Q EY++ RE
Sbjct: 163 QLEYNVATRE 172
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 68.5 bits (160), Expect = 4e-10
Identities = 51/187 (27%), Positives = 95/187 (50%), Gaps = 23/187 (12%)
Query: 107 LGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKR 166
LGK+G R+ +IG+G W M S + + L+ G N D +EA+ + EA +GR ++ R
Sbjct: 5 LGKTGERISSIGIGTWQMKSNDQSIMAIRAGLDAGSNFVDTAEAY--RNEAMVGRAIESR 62
Query: 167 NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVD 226
V I TK+ F + + D +I + + SL RL V+ ID+ LH +
Sbjct: 63 EV-----FIATKV-----FPNHFKYDS-------LIRACENSLKRLNVKTIDLYQLHWPN 105
Query: 227 PVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFC 286
++E ++ M ++++ G + Y G + ++ +E+ A + ++ ++ Q EY+
Sbjct: 106 RHVDIKETMKAMEHLVDTGMIRYIGVSNFNVNELKSAMSAMSKYEIVS---NQVEYNPLV 162
Query: 287 RE-KPEL 292
R +PE+
Sbjct: 163 RYIEPEI 169
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 68.1 bits (159), Expect = 5e-10
Identities = 55/210 (26%), Positives = 103/210 (49%), Gaps = 29/210 (13%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM--------LSEESIEDVVMTALENGINLFDLSEAHCAKG 155
YK LG++G +P +GLG W + +E + +++ TA++ G D +E +
Sbjct: 3 YKELGRTGEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGH 62
Query: 156 EAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
EL G+ +K + RR + I +K+ W T L R ++ S++ +L RL
Sbjct: 63 TEELIGKAIK--DFRREDLFIVSKV-WPTH-----------LRRDDLLRSLENTLKRLDT 108
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+Y+D+ L+H +P P+EE + M + +G + Y G + + + +A + ++
Sbjct: 109 DYVDLYLIHWPNPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQE----- 163
Query: 275 PIV-EQTEYHMFCREKPELYMPELYHKIGV 303
PIV +Q +Y++ R+ + E K GV
Sbjct: 164 PIVCDQVKYNIEDRDPERDGLLEFCQKNGV 193
>UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase
family; n=28; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Streptococcus pneumoniae
Length = 308
Score = 68.1 bits (159), Expect = 5e-10
Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 10/160 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTML--SEESIEDVVMTALENGINLFDLSEAHCAKGEAE- 158
+RY LG+ + I LG+ + S + +E++V TAL GIN FDL++ + +G E
Sbjct: 1 MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGINAFDLADIY-GRGRCEE 59
Query: 159 -LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
LG +LK R R + I +K + D S+ ++I+SV L RL+++++
Sbjct: 60 LLGLVLKNRPDLREKMWIQSKC--GIRIEEFTYFD---FSKDYIIKSVDGILQRLKIDHL 114
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
D +LLH+ D + +++ N + +G V +G + +P
Sbjct: 115 DSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNP 154
>UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=17; Bacillales|Rep: Oxidoreductase, aldo/keto
reductase family - Staphylococcus aureus (strain USA300)
Length = 302
Score = 68.1 bits (159), Expect = 5e-10
Identities = 51/172 (29%), Positives = 92/172 (53%), Gaps = 9/172 (5%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSE-ESIEDVVMTALENGINLFDLSEAHCAKG--EAELGR 161
KN+ KSG+ + +GLG ++ ++ + E ++ A+ENGI FD ++ + KG E+ +G+
Sbjct: 3 KNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMY-DKGINESVVGK 61
Query: 162 ILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVL 221
L K +R I I TK+ + T + S S+ ++ E+VK SL RL +++ID+
Sbjct: 62 ALLKYQ-QRDDIFIGTKV--GNRL-TKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQ 117
Query: 222 LHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
LH P++E + + + EG + +G + P+ ++D Y Q I
Sbjct: 118 LHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPN-VIDYYLKHSQIETI 168
>UniRef50_Q1IH94 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:
Aldo/keto reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 358
Score = 68.1 bits (159), Expect = 5e-10
Identities = 54/201 (26%), Positives = 95/201 (47%), Gaps = 14/201 (6%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCA-KG 155
Y LG+SGL+V + LG T +E++ + L+ G N D + +
Sbjct: 6 YNVLGRSGLKVSPLCLGTMTFGTEWGWGSAEDTARQIFNAYLDAGGNFIDTANGYTGGTS 65
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G+ +K R R I++ TK ++ N G RK++ +V+ASL RLQ +
Sbjct: 66 ETLIGKFIKDRG-DRDRIVLATKFAFAMGEGDPNGG---GNGRKNIYAAVEASLRRLQTD 121
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ +H D P+EE++ + ++ EG V Y G + SP+ + + +F+ +
Sbjct: 122 YLDLYWVHNWDRFTPVEEVMATLTGLVREGKVRYIGMSN-SPAWYVARAQSLAEFHGLEK 180
Query: 276 IVE-QTEYHMFCREKPELYMP 295
Q EY + R ++P
Sbjct: 181 FCAWQLEYSLLERNIEREHIP 201
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 68.1 bits (159), Expect = 5e-10
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 21/177 (11%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G VP +GLG W L+ +S + V TAL G D ++A+ E ++G + V R
Sbjct: 8 GTSVPALGLGTW-QLTGQSCRETVETALGMGYRHIDTAQAY--GNERQVGLGMDAAAVDR 64
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDP--V 228
+ +TTK+ S + DER + R S + SL +L +Y+D++L+H + +
Sbjct: 65 EDVFLTTKLDGSNR-------DERSVRR-----STRESLNKLGTDYLDLLLIHWPNTPWM 112
Query: 229 CPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMF 285
+ E + MN V+ EG V + G + +SPS ++D R + +Q +YH +
Sbjct: 113 ASLSETLGAMNDVVEEGLVRHIGVSNFSPS-LLD---RARDISSAPIFTDQVQYHPY 165
>UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga
maquilingensis IC-167|Rep: Aldo/keto reductase -
Caldivirga maquilingensis IC-167
Length = 337
Score = 67.7 bits (158), Expect = 7e-10
Identities = 54/202 (26%), Positives = 96/202 (47%), Gaps = 15/202 (7%)
Query: 108 GKSGLRVPNI---GLGLWTMLSEESIEDVVMTALENGINLFDLSEAHC-AKGEAELGRIL 163
G + PN+ G W +++++ V+ A + GIN D + + + E +G ++
Sbjct: 19 GAMSIGDPNLQSHGSSSWVAGRDQALK-VLKRAWDLGINFIDTANVYSRGRSEEIVGELV 77
Query: 164 KKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
K R ++I TK++ N + RGLSRKH++ V+ SL RL YID+ +H
Sbjct: 78 KGM---REDVVIATKVFGQM----GNGPNARGLSRKHIMWQVRESLRRLNTGYIDLYQIH 130
Query: 224 KVDPVCPMEELVRVMNYVINEGWVMYWG-TARWSPSEIMDAYTNCRQFNCITPIVEQTEY 282
+ D P+EE + + ++++G V Y G ++ W+ YT + Q Y
Sbjct: 131 RFDYDTPIEETLSTLTDLVHQGLVRYIGASSMWTWQFAKMIYT-AEMKGYEKFVSMQNVY 189
Query: 283 HMFCREKPELYMPEL-YHKIGV 303
++ RE+ +P H IG+
Sbjct: 190 NLLYREEEREMIPFCKAHGIGI 211
Score = 35.5 bits (78), Expect = 3.5
Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 394 LAVPEMRSS---GSKEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNC 450
+ VPE + GS + EP + LR + +AN+ + +Q+A AW L ++ V
Sbjct: 232 IIVPETETRVRPGSGDYRIYVEPPENAEILRRVIEVANNKGATPTQIAYAWLL-HKGVTA 290
Query: 451 LLLGATSVEQFKENIHALQV 470
++G T E +E ++A+ +
Sbjct: 291 PIIGTTKPEHVEEAVNAISI 310
>UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related
oxidoreductase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: Aryl-alcohol dehydrogenase-related
oxidoreductase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 314
Score = 67.3 bits (157), Expect = 9e-10
Identities = 49/181 (27%), Positives = 93/181 (51%), Gaps = 21/181 (11%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGE 156
Y L K+ L+V + +G W + E ++AL+ GIN D ++A+ KG+
Sbjct: 8 YITLPKTDLKVSRLSIGTWLFGGLRWGYVDNRESEKTFLSALDLGINFIDTADAY-GKGQ 66
Query: 157 AE--LGRILKKRNVRRTSIIITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
+E + R+ K R + +++I TK + W+T R D LS++H+ E+ + SL RL
Sbjct: 67 SEEFVSRLTKGR---KENLVIGTKAGVVWNTD--GTRRID---LSKRHLTEAAERSLQRL 118
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
+++ ID+ LH+ D +EE + + + +G + Y G + + P E + + + +C
Sbjct: 119 KLDKIDLYYLHEPDVNTDIEETIEALQLLKAQGKIRYIGLSNF-PKETVAQFNSMMHVSC 177
Query: 273 I 273
+
Sbjct: 178 L 178
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 1/139 (0%)
Query: 332 PLADIGSAREVRRVKLLNNANSMMVWSAITTGKGLGREEITGLFAKSRFNRKYSTFSWCE 391
P + + V L + S++ A T +E G A S ++ T + +
Sbjct: 162 PKETVAQFNSMMHVSCLQDELSLIRREAELTNLKFAKENNLGFLAYSPLSKGLLTGKF-K 220
Query: 392 EDLAVPEMRSSGSKEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCL 451
D P + E +GE + +K+ L+ A L + S +++AW L +SV +
Sbjct: 221 FDSQFPSDDNRSGNEDFSGERLKKNIEKVAILSQFAKRLGYTASAVSIAWVLGIDSVTSV 280
Query: 452 LLGATSVEQFKENIHALQV 470
+LGA + EQ +E + +L+V
Sbjct: 281 VLGARTQEQLEEQMKSLEV 299
>UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11;
Proteobacteria|Rep: Aldo/keto reductase - Mesorhizobium
sp. (strain BNC1)
Length = 355
Score = 66.9 bits (156), Expect = 1e-09
Identities = 53/199 (26%), Positives = 88/199 (44%), Gaps = 19/199 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE-----------ESIEDVVMTALENGINLFDLSEA 150
L Y+ LG SGL V + LG T E S +V A++ G+N D +
Sbjct: 6 LEYRQLGSSGLSVSVLTLGTMTFGGEGVFAKVGTTDLRSAARLVDMAVDAGVNHIDTANV 65
Query: 151 HCAKGEAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ + E+ G +++ + R ++I TK N +ERG R H+I +ASL
Sbjct: 66 YSSGASEEIVGEVVQGK---RDKLLIATK----AGMPAGNGPNERGSGRAHLIAQCEASL 118
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RL+ ++ID+ +H D + P+EE + + + G + Y G + +S +M A
Sbjct: 119 RRLKTDHIDLYYVHAWDGLTPLEETLGALQTLQEHGKIRYTGCSNFSGWHVMKALGVAES 178
Query: 270 FNCITPIVEQTEYHMFCRE 288
+Q Y + RE
Sbjct: 179 HGFPRFCSQQIHYTLLARE 197
Score = 39.9 bits (89), Expect = 0.16
Identities = 16/53 (30%), Positives = 34/53 (64%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+ +L ++A S + +Q+A+AW ++ V+ L++GATS +Q +N+ A + +
Sbjct: 258 VEELVDVAQSRGATAAQVALAWTMRRPGVSNLIIGATSEKQLADNLAAADLVL 310
>UniRef50_Q0UI32 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 66.9 bits (156), Expect = 1e-09
Identities = 49/178 (27%), Positives = 89/178 (50%), Gaps = 25/178 (14%)
Query: 104 YKNLGKSGLRVP-------NIGLGLWT--MLSEESIEDVVMTALENGINLFDLSEAHC-A 153
Y+ LG SGL+V +IG W ++ EE ++ A + G+ +D + +
Sbjct: 18 YRRLGNSGLKVSVPILGAMSIGSSKWQPWVIEEEESLPLLKAAYDRGLTTWDTANVYSNG 77
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWST---------KFHTN-----NRSDERGLSRK 199
E +G+ +KK + R ++I TK Y T ++ T + +++ GLSR+
Sbjct: 78 VSEEIIGKAIKKYELPRHKLVILTKCYGYTGEDPGLRTIQYGTELPQLRDYTNQGGLSRQ 137
Query: 200 HVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG-TARWS 256
+ V ASL RL +YID++ +H+ D P+EE + ++ ++ G V Y G ++ W+
Sbjct: 138 AIFNQVNASLKRLDTDYIDLLQIHRFDHNTPIEETMEALHDLVKSGKVHYIGASSMWA 195
>UniRef50_Q3WFM1 Cluster: Aldo/keto reductase:Bacterial regulatory
protein, TetR; n=1; Frankia sp. EAN1pec|Rep: Aldo/keto
reductase:Bacterial regulatory protein, TetR - Frankia
sp. EAN1pec
Length = 540
Score = 66.5 bits (155), Expect = 2e-09
Identities = 63/233 (27%), Positives = 111/233 (47%), Gaps = 24/233 (10%)
Query: 89 GNHTAMPSAVTPGLRYKNLGKSGLRVPNIGLGLWTMLSEESIED------VVMTALENGI 142
G A+P A P + Y+ LG+SGL V + LG+ + + + D V+ L+ G
Sbjct: 231 GEGPAVPRASWP-MEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGG 289
Query: 143 NLFDLSEA-HCAKG-------EAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDE 193
NL D + A +G AEL GR ++ R R+S+++ + S + +
Sbjct: 290 NLLDTTAAGDIGRGGTDPDGAAAELCGRAVRDR---RSSVVLAS----SVGRPSGQGPHD 342
Query: 194 RGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
G SR+H+ + +A+L RL+ +Y+D++ L DP P+EE + ++ ++ G V+Y G A
Sbjct: 343 GGNSRRHIRAACEATLRRLRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVGVA 402
Query: 254 RWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ A + + I + Y + RE ++P L + G+G I
Sbjct: 403 NLHVYRVTKALSVSDRLGRARFISFRGPYGLLSRELEHEHLPLLAEE-GLGLI 454
>UniRef50_Q5TG84 Cluster: Potassium voltage-gated channel,
shaker-related subfamily, beta member 2; n=5;
Hominidae|Rep: Potassium voltage-gated channel,
shaker-related subfamily, beta member 2 - Homo sapiens
(Human)
Length = 173
Score = 66.5 bits (155), Expect = 2e-09
Identities = 34/72 (47%), Positives = 47/72 (65%), Gaps = 5/72 (6%)
Query: 104 YKNLGKSGLRVPNIGLGLWT----MLSEESIEDVVMTALENGINLFDLSEAHCA-KGEAE 158
Y+NLGKSGLRV +GLG W +++E E ++ A +NGINLFD +E + A K E
Sbjct: 39 YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVV 98
Query: 159 LGRILKKRNVRR 170
LG I+KK+ R+
Sbjct: 99 LGNIIKKKGWRQ 110
>UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 354
Score = 66.5 bits (155), Expect = 2e-09
Identities = 40/159 (25%), Positives = 88/159 (55%), Gaps = 14/159 (8%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSE------ESIEDVVMTALENGINLFDLSEAHC-AKGE 156
Y+ +G + + V IG+G+W+++++ ED++ A E GIN +D ++ + KGE
Sbjct: 31 YRRIGDTNITVSEIGIGVWSLVTDWWGADTNKAEDIIRRAYEVGINFYDTADTYGEGKGE 90
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
+ ++L+ +R +I+I TKI + +H + ++ ++K SL RL+ +Y
Sbjct: 91 EIIAKVLE---TKRDNIVILTKIGYDF-YHKEGGKIRQRFDIPYLEFALKRSLERLRTDY 146
Query: 217 IDVVLLH--KVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
ID++++H K++ + + E++ + + +G + +G A
Sbjct: 147 IDILMIHNPKMNAIKNL-EILSFLRSLKKDGIIRMYGVA 184
>UniRef50_Q1NH47 Cluster: Rhizopine catabolism protein; n=7;
Proteobacteria|Rep: Rhizopine catabolism protein -
Sphingomonas sp. SKA58
Length = 359
Score = 66.1 bits (154), Expect = 2e-09
Identities = 52/209 (24%), Positives = 104/209 (49%), Gaps = 17/209 (8%)
Query: 104 YKNLGKSGLRVPNIGLGLWTM-----LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
Y+ LG+SGLRV + LG T E+ + + ++ G N D + + A G +E
Sbjct: 18 YRLLGRSGLRVSPLALGTMTFGEEWGADEQESRRIFDSYVDQGGNFIDTA-GYYADGASE 76
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
+ K +R ++++TK + N + G SR++++++V+ SL RL+ + ID
Sbjct: 77 I-LAGKFAEAKRERLVLSTKYSLTRSVGDPNAA---GNSRRNMVQTVETSLKRLKTDRID 132
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWG---TARWSPSEIMDAYTNCRQFNCITP 275
+ LH D + P +E++R + ++ +G ++Y G T W + + + R ++ +
Sbjct: 133 LFFLHVWDDMTPADEILRAFDDLVTQGKILYLGLSDTPAWQMAR-LQTMSELRGWSQLVA 191
Query: 276 IVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ Q+EY++ R +P +G+G
Sbjct: 192 L--QSEYNLVERTAERDLIPAA-KALGIG 217
Score = 39.9 bits (89), Expect = 0.16
Identities = 17/48 (35%), Positives = 32/48 (66%)
Query: 426 LANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIK 473
+A+ + + +Q+A+AW L N +V LLGA ++ Q+ +N+ AL V ++
Sbjct: 271 VADEMGVTSAQVAIAWTLANPAVVSPLLGARTMRQYADNVAALSVRLE 318
>UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina
ATCC 23134|Rep: Oxidoreductase - Microscilla marina ATCC
23134
Length = 299
Score = 66.1 bits (154), Expect = 2e-09
Identities = 45/163 (27%), Positives = 83/163 (50%), Gaps = 7/163 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIE-DVVMTALENGINLFDLSEAH-CAKGEAEL 159
++Y LG+S L+V I G ++ S ++ VV AL+ GIN FD ++ + K E L
Sbjct: 1 MKYNQLGRSSLQVSQIAFGCMSLQSTQAQPVRVVREALDLGINFFDTADLYEQGKNEILL 60
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
GR L + +R +II TK+ +++ + + ++I +++ SL RL +YID+
Sbjct: 61 GRALGQ---KRQEVIIATKV--GNQWNAEGTAWNWNPRKDYIITAIENSLKRLSTDYIDL 115
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
LH P++E++ + G + +G + P+ I +
Sbjct: 116 YQLHGGTIDDPIDEVIEAFEQLKTHGKIRAYGISSIRPNVIRE 158
>UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium
adolescentis|Rep: Oxidoreductase - Bifidobacterium
adolescentis (strain ATCC 15703 / DSM 20083)
Length = 326
Score = 66.1 bits (154), Expect = 2e-09
Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 107 LGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE------ 158
+GKS + LG+ M L ++ +VV TA E+G+N FD ++ + +
Sbjct: 6 IGKSAVVASQAALGVMRMDALDADAAAEVVRTAAEHGVNFFDTADIYGFNVNRDHASSRV 65
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNR--SDERGLSRKHVIESVKASLGRLQVEY 216
LGR K ++R I + TK + F N + S KH+I + L L +Y
Sbjct: 66 LGRAWKDAGLKREDIFLQTKFGINIDFSDPNNVHATRYDFSAKHLITRLDEELEALGTDY 125
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
+D LLH+ D + EE+V + G V ++G + +P
Sbjct: 126 VDFALLHRPDTLMEAEEIVEAFTTLHKAGKVRHFGVSNVNP 166
>UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter sp.
FB24|Rep: Aldo/keto reductase - Arthrobacter sp. (strain
FB24)
Length = 330
Score = 66.1 bits (154), Expect = 2e-09
Identities = 41/134 (30%), Positives = 66/134 (49%), Gaps = 3/134 (2%)
Query: 128 ESIEDVVMTALENGINLFDLSEAH-CAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFH 186
E + AL++GI+LFD ++ + K EA G +L R I + TK + +
Sbjct: 43 EQAAAAIDAALDSGISLFDHADIYRSGKSEAVFGEVLAITPGLRERIRLQTKC--GIRLN 100
Query: 187 TNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGW 246
LSR ++E V SL RL+ +Y+DV+LLH+ DP+ E+ + ++ EG
Sbjct: 101 EQGLETHYDLSRDSILERVNGSLKRLKTDYVDVLLLHRPDPLADPAEVASAVGQLMQEGK 160
Query: 247 VMYWGTARWSPSEI 260
V G + S +I
Sbjct: 161 VRQVGVSNMSAPQI 174
>UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative,
expressed; n=11; Magnoliophyta|Rep: Auxin-induced
protein PCNT115, putative, expressed - Oryza sativa
subsp. japonica (Rice)
Length = 343
Score = 65.7 bits (153), Expect = 3e-09
Identities = 61/207 (29%), Positives = 100/207 (48%), Gaps = 22/207 (10%)
Query: 107 LGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAK-GEAE 158
LG GL V +G G + ++EE VV A E G+ FD S+A+ E
Sbjct: 11 LGTQGLEVSKLGFGCMGLTGVYNAPVAEEDGVAVVRRAFEAGVTFFDTSDAYGPHTNEVL 70
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
LG+ LK+ + R + + TK + F N +G + +V +ASL RL V+YID
Sbjct: 71 LGKALKQ--LPREKVQVATK-FGIAGFDANGML-VKG-TPDYVRACCEASLERLAVDYID 125
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
+ H++D P+EE + + ++ EG V + G + S I R+ + + PI
Sbjct: 126 LYYQHRIDQSVPIEETMGELKKLVEEGKVKFVGLSEASADTI-------RRAHAVYPITA 178
Query: 279 -QTEYHMFCREKPELYMPELYHKIGVG 304
Q E+ ++ R+ E +P L ++G+G
Sbjct: 179 VQMEWSLWTRDIEEEIIP-LCRELGIG 204
Score = 34.3 bits (75), Expect = 8.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
+ LA CS +QLA++W L + G T V+ +NI A++V + K
Sbjct: 252 IEELATKYGCSPAQLALSWVLHQGDDVVPIPGTTKVKNLDDNIGAVKVKLSK 303
>UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=12;
Bacillales|Rep: Uncharacterized oxidoreductase yccK -
Bacillus subtilis
Length = 310
Score = 65.7 bits (153), Expect = 3e-09
Identities = 47/167 (28%), Positives = 84/167 (50%), Gaps = 14/167 (8%)
Query: 105 KNLGKSGLRVPNIGLG--------LWTMLSEESIEDVVMTALENGINLFDLSEAH-CAKG 155
+ LGK+ L+V IG G L+ L++E+ +D+V TAL+ G+N D + + +
Sbjct: 5 RTLGKTKLKVKRIGFGANAVGGHNLFPNLNDETGKDLVRTALDGGVNFIDTAFIYGLGRS 64
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +G ++++R VR II T + + S E SR+ + V+ SL RL+ +
Sbjct: 65 EELIGEVVQERGVRNELIIATKGAHKEV-----DGSIELDNSREFLRSEVEKSLKRLKTD 119
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
YID+ +H D P+ E+ + + +EG + G + ++ D
Sbjct: 120 YIDLYYVHFPDGKTPLAEVAGTLKELKDEGKIKAIGASNLDYQQLQD 166
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 65.3 bits (152), Expect = 4e-09
Identities = 53/188 (28%), Positives = 90/188 (47%), Gaps = 23/188 (12%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G ++P IGLG T L ++ ++ + ALE GI LFD + + E E+G +++ N+ R
Sbjct: 42 GYQIPIIGLGT-TSLHNQTCKNAIKAALEIGIRLFDTASLY--GNEKEVGETIRESNINR 98
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCP 230
I + TK+Y +F + +++ +L +L +YID++LLH P
Sbjct: 99 NEIFVITKLYPGAQFANPEK-------------AIEEALNKLNTDYIDMMLLH--HPGEN 143
Query: 231 MEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKP 290
+ + + I +G + G + W EI Q N I P + Q E H++ +EK
Sbjct: 144 DVKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLP---QIN-IKPSLIQNEIHIYYQEKE 199
Query: 291 EL-YMPEL 297
+ YM L
Sbjct: 200 VVPYMHNL 207
>UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 306
Score = 64.5 bits (150), Expect = 7e-09
Identities = 43/158 (27%), Positives = 79/158 (50%), Gaps = 10/158 (6%)
Query: 106 NLGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCAKGEAEL-GRI 162
NLG S ++ ++ LG+ M L V+ TA + GIN D ++ + + + G+
Sbjct: 5 NLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTIFGQA 64
Query: 163 LKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
LK+ +V R + I +K R D S++H++ +V L RL V+Y+D LL
Sbjct: 65 LKQAHVSRDQLYIQSK----GGIVPGKRYD---FSKQHILAAVDGELQRLGVDYLDTFLL 117
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
H+ D + EE+ + + G V ++G + ++P ++
Sbjct: 118 HRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQV 155
>UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 329
Score = 64.5 bits (150), Expect = 7e-09
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 13/190 (6%)
Query: 111 GLRVPNIGLGLWTMLSEESIED-----VVMTALENGINLFDLSEAHCAKGEAE-LGRILK 164
GL++P L L TM +++++ +V AL+ GI D + A+ E L R+LK
Sbjct: 12 GLKLPISRLVLGTMTFGDTVDEATAGRMVEEALDAGITTIDTANAYVGGTTEEMLSRLLK 71
Query: 165 KRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHK 224
R R +I+ +K H +N LS + SV+ SL RL V+ ID+ LH+
Sbjct: 72 GR---RGDVILASKAGMPHADHGSNSP----LSPAGLRASVEGSLRRLGVDSIDLFYLHQ 124
Query: 225 VDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHM 284
D P+ + + + + EG + G + ++ +I D R+ P+V Q Y++
Sbjct: 125 PDRATPLRDTLATVAELFAEGKICALGVSNFAAWQIADVIHTAREVGAPRPVVAQQLYNL 184
Query: 285 FCREKPELYM 294
R E Y+
Sbjct: 185 VARRVEEEYL 194
Score = 40.3 bits (90), Expect = 0.12
Identities = 16/51 (31%), Positives = 31/51 (60%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
D + +L+ +A+ S+++L++ W + V +LLG + VEQ + NI A+
Sbjct: 250 DAIEELSRIADGAGISLAELSLRWLAYRDGVGSMLLGGSKVEQLQSNIAAV 300
>UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3;
Trichocomaceae|Rep: Aldo/keto reductase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 345
Score = 64.5 bits (150), Expect = 7e-09
Identities = 60/192 (31%), Positives = 93/192 (48%), Gaps = 20/192 (10%)
Query: 105 KNLGKSGLRVPNIGLGL-----WTMLSEESIED---VVMTALENGINLFDLSEAHCAKGE 156
+ LGK+G VP +GLGL W S S E+ V+ A+E G +D S+ + E
Sbjct: 9 RQLGKNGPTVPALGLGLMGMSFWVYGSIPSDEERFKVLDRAVELGETFWDTSDLY-GDNE 67
Query: 157 AELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEY 216
LG+ + R +R I + TK F + E S ++ ++ ASL RL V+
Sbjct: 68 ELLGKWFR-RTGKRDQIFLATKF----GFVQGGKPHEINSSAEYCKKACDASLKRLGVDS 122
Query: 217 IDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
ID+ LH +P P+EE +R M + EG + + G + S + + A C+ N +
Sbjct: 123 IDLYYLHSPNPQTPIEETMRAMAELQAEGKIKHIGVSSVSSATLRRA---CKIANV---V 176
Query: 277 VEQTEYHMFCRE 288
QTEY +F R+
Sbjct: 177 AVQTEYCVFSRD 188
Score = 39.1 bits (87), Expect = 0.29
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 411 EEPRTYGDKLRD-LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQ 469
EE R K+ A LA C++SQLA+AW LK + + G VE +EN ALQ
Sbjct: 245 EENRERNVKVASQFAALAEKKGCTVSQLALAWLLKQGNDIFAIPGTRRVEYLEENWAALQ 304
Query: 470 VYIKKIFKVCVKSF 483
+ + + +++F
Sbjct: 305 ISLTDSEEAEIRTF 318
>UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 342
Score = 64.1 bits (149), Expect = 9e-09
Identities = 56/202 (27%), Positives = 92/202 (45%), Gaps = 21/202 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLW-------TMLSEES-------IEDVVMTALENGINLFDL 147
++Y+ LG S L+V +I LG T L++ S V+ A+ GIN FD
Sbjct: 1 MQYRQLGTSDLKVSSIALGCMGFGAGTGTALNQRSWAVGQTQANQVLDRAISLGINFFDT 60
Query: 148 SEAHCA-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVK 206
+ + A E LG+ LKK +R +++ TK T N R+HV+ S+
Sbjct: 61 APVYQAGASERVLGQGLKK--FQRDQLVLATKFTNRTTQEIENHVS----GREHVLRSLD 114
Query: 207 ASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTN 266
SL LQ +Y+D+ + H D + PM E++ +N + G V Y G + +I
Sbjct: 115 QSLQNLQTDYVDLYIYHIWDWLTPMAEIMAGLNEAVQAGKVRYIGISNAYSWQIAQINAL 174
Query: 267 CRQFNCITPIVEQTEYHMFCRE 288
++ + Q+ Y++ RE
Sbjct: 175 AVRYGYPQFVSIQSHYNLVYRE 196
>UniRef50_A5CUU8 Cluster: Putative oxidoreductase; n=1; Clavibacter
michiganensis subsp. michiganensis NCPPB 382|Rep:
Putative oxidoreductase - Clavibacter michiganensis
subsp. michiganensis (strain NCPPB 382)
Length = 328
Score = 64.1 bits (149), Expect = 9e-09
Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 22/219 (10%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGL----WTMLSEESIEDVVMTALENGINLFDLSEAHC--- 152
PG R + LG SG+ V +GLG WT EE+ ++ E G D + ++
Sbjct: 6 PGPRTRALGTSGVVVSTLGLGTSGFGWTADREEAWA-ILDAYREEGGTFVDTASSYSQWV 64
Query: 153 ---AKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKA 207
A GE+E +G L R R +++ TK+ D G S + V A
Sbjct: 65 PGHAGGESEAIIGGWLAARGCR-DDLVVGTKV--------GKSRDAPGTSADSIRRGVDA 115
Query: 208 SLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNC 267
SL RL ++DVV H D P+EE V ++ ++ EG G + + P I +A
Sbjct: 116 SLRRLGTGHVDVVHAHLDDTRTPLEETVAALSDLVKEGKARLVGVSGFRPERIEEALALA 175
Query: 268 RQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ V Q EY + R+ E + L + G+G +
Sbjct: 176 HGSGAVPVGVVQEEYSLLARDHAEGRLQALVRQEGLGLV 214
Score = 36.7 bits (81), Expect = 1.5
Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Query: 364 KGLGREEITGLFAKSRFNRKYSTFSWCEEDLAVPEMRSSGSKEQVTGEEPRTYGDKLRDL 423
+ L R+E GL A S + + T + AVP R+ +++ ++ T +R
Sbjct: 203 QALVRQEGLGLVAHSVLAKGFLTGKYLPGAPAVPSARALDAEQYMSAGGHAT----VRTA 258
Query: 424 ANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI 472
+A +++++A+AW L + L+GA + Q ++ + A Q+ +
Sbjct: 259 EEIARMRGVTVAEVAIAWVLGRPGIASALVGARTARQIRQLMPAAQLVL 307
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 63.7 bits (148), Expect = 1e-08
Identities = 54/207 (26%), Positives = 100/207 (48%), Gaps = 31/207 (14%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELG--RILKKRN 167
+G ++P +GLG W M + + V A++NG D ++A+ + E G + K
Sbjct: 9 NGYKIPKLGLGTW-MSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAKGY 67
Query: 168 VRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH---- 223
V+R + +TTK+ WST H + R +ES+K +LQ+EY+D+ ++H
Sbjct: 68 VKREELFVTTKL-WSTDKHKED-------VRPACLESLK----KLQLEYLDLYIIHIPLT 115
Query: 224 -------KVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI 276
+ + P+EE R M ++ EG V G + ++ ++ + + I P
Sbjct: 116 ADKKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAK----IQPA 171
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGV 303
V Q E+H++ ++P+L+ H I +
Sbjct: 172 VNQFEFHIY-YQRPKLHQFCKKHNIHI 197
>UniRef50_Q8NQC2 Cluster: Predicted oxidoreductases; n=5;
Corynebacterineae|Rep: Predicted oxidoreductases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 316
Score = 63.7 bits (148), Expect = 1e-08
Identities = 67/275 (24%), Positives = 118/275 (42%), Gaps = 22/275 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIE---DVVMTALENGINLFDLSEAHCAKGEAE 158
++ + +G SGLRV +GLG T S + D+ + +G L D+S + E
Sbjct: 1 MKQRMVGSSGLRVSRLGLGTSTWGSGTELAEAGDIFKAFINSGGTLIDVSPNYTTGVAEE 60
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
+ + V R++++I++ + R D SR+++I + +L L +Y+D
Sbjct: 61 MLGTMLDAEVSRSAVVISSSAGVNPALPLGRRVD---CSRRNLIAQLDVTLRALNTDYLD 117
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSE--IMDAYTNCRQFNCITPI 276
+ + D P E+ ++Y + G V Y G +S + + A +N + +
Sbjct: 118 LWSVGYWDEGTPPHEVADTLDYAVRTGRVRYAGVRGYSGWQLAVTHAASNHAAASARPVV 177
Query: 277 VEQTEYHMFCREKPELYMPELYHKIGVGKI----YILFFIQLNYRSLVPCNSIWVKLLKP 332
V Q EY + R + +P H +GVG + YRS +P +S
Sbjct: 178 VAQNEYSLLERRAEQELLPATQH-LGVGFFAGAPLGQGVLTAKYRSEIPHDS-------R 229
Query: 333 LADIGSAREVRRVKLLNNANSMMVWSAITTGKGLG 367
A G EV+ L+N ++V + T KGLG
Sbjct: 230 AASTGRDAEVQ--SYLDNRGRIIVDALDTAAKGLG 262
>UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3;
Actinomycetales|Rep: Possible oxidoreductase -
Streptomyces fradiae
Length = 352
Score = 63.7 bits (148), Expect = 1e-08
Identities = 63/213 (29%), Positives = 98/213 (46%), Gaps = 18/213 (8%)
Query: 102 LRYKNLGK-SGLRVPNIGLGLWTMLSE------ESIEDVVMTALENGINLFDLSEAHCAK 154
+RY+ G+ SGLRV LG S E + + ++ G D+S +
Sbjct: 1 MRYQTFGRHSGLRVSEYVLGTANFGSSPAAAGREGARAIFESFVDAGGTTVDVSNIY-QD 59
Query: 155 GEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
GEAE LG+++ +R R ++ TK S H + G SRK ++ S++ SL RL
Sbjct: 60 GEAETLLGQLMGQR---RDDYVVITKYSGSRSAHVPPGTT--GNSRKVMVRSLEESLRRL 114
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
+ +Y+DV + H D V PM E++ +I G + Y G + + + A
Sbjct: 115 RTDYVDVFMPHLPDGVTPMPEILAGFEDLIRAGKIRYGGLSNFPAWRVAGAAVRSELSGR 174
Query: 273 ITPIVEQTEYHMFCR--EKPELYMPELYHKIGV 303
+ I QTEY + R E+ L M E H +GV
Sbjct: 175 VPLIGIQTEYSLAERSAEREILPMAEA-HGLGV 206
>UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:
Aldo/keto reductase - Ochrobactrum anthropi (strain ATCC
49188 / DSM 6882 / NCTC 12168)
Length = 331
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/171 (26%), Positives = 78/171 (45%), Gaps = 18/171 (10%)
Query: 105 KNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAH-CAKGE 156
+ +G+SG+R +GLG W + E + +L+ G+ L D + A+ + E
Sbjct: 8 REIGRSGVRASAVGLGTWAIGGWMWGGTDEAQSIAAIQASLDAGVTLIDTAPAYGLGRSE 67
Query: 157 AELGRILKKRNVRRTSIIITTK--IYWSTK-----FHTNNRSDERGLSRKHVIESVKASL 209
+G+ + R R +I TK + W T+ F + R L R +I V+ SL
Sbjct: 68 EIVGKAIAGR---RDKAVIATKCGLVWHTQKGQHFFDQDGNPVHRYLGRDAIIHEVEESL 124
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
RL +YID+ + H DP P+EE V + + G + G + + E+
Sbjct: 125 RRLGTDYIDLYITHWQDPTTPIEETVAALEELKQAGKIRAVGASNLNRPEL 175
>UniRef50_A5G9P4 Cluster: Aldo/keto reductase precursor; n=1;
Geobacter uraniumreducens Rf4|Rep: Aldo/keto reductase
precursor - Geobacter uraniumreducens Rf4
Length = 363
Score = 63.7 bits (148), Expect = 1e-08
Identities = 53/205 (25%), Positives = 96/205 (46%), Gaps = 21/205 (10%)
Query: 112 LRVPNIGLGLWTMLS--------EESIEDVVMTALENGINLFDLSEAHCAKGEAEL-GRI 162
L V IGLG +M S + + ++ A++ G+ FD +EA+ EL G
Sbjct: 45 LEVSAIGLGCMSMNSGNYNPPKDKREMIRLIHAAVDRGVTYFDTAEAYGPFVNEELVGEA 104
Query: 163 LKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
L R ++I TK + + T R+ +H+ + +ASL RL+ + ID++
Sbjct: 105 LVPF---RGKVVIGTKFGFDIDYATGRRTGGLNSRPEHIRKVAEASLKRLRTDAIDLLYQ 161
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE-QTE 281
H+VDP P+E++ + +I EG V ++G + R+ + + P+ Q E
Sbjct: 162 HRVDPKVPIEDVAGTVKELITEGKVKHFGLSE-------PGMQTLRRAHAVQPVAAVQNE 214
Query: 282 YHMFCREKPELYMPELYHKIGVGKI 306
Y + R PE ++ ++G+G +
Sbjct: 215 YSLLWR-GPEKEELAIFEELGIGLV 238
>UniRef50_A4AHH2 Cluster: Oxidoreductase; n=3; Actinobacteria
(class)|Rep: Oxidoreductase - marine actinobacterium
PHSC20C1
Length = 330
Score = 63.7 bits (148), Expect = 1e-08
Identities = 50/210 (23%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 100 PGLRYKNLGKSGLRVPNIGLGL----WTMLSEESIEDVVMTALENGINLFDLSEAHCA-K 154
P + +G S LRV + L WT + + ++ T + G N D ++++ + +
Sbjct: 22 PHFTTRVIGSSDLRVFPVALSGNVFGWTA-DDPATTSILDTFADGGGNFIDTADSYASGR 80
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E +GR ++ R R +I++ TK+ + G+ + + SV ASL RL
Sbjct: 81 SELMIGRWMRDRR-NRDNIVVATKV--------GKSRENPGMRAEAIKRSVAASLSRLGT 131
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+ID++ LH D +E + ++ +I EG V Y+G + + + ++ A C Q
Sbjct: 132 SHIDLLYLHVDDESVDFDETLLAVDELIGEGKVRYFGGSDHTGNRLIQARIACGQMGVAP 191
Query: 275 PIVEQTEYHMFCREKPELYMPELYHKIGVG 304
+ Q+ Y++ R+ E + + G+G
Sbjct: 192 MVAVQSHYNLLHRKDYETGLAHVAAIQGLG 221
>UniRef50_O25804 Cluster: Aldo-keto reductase, putative; n=5;
Proteobacteria|Rep: Aldo-keto reductase, putative -
Helicobacter pylori (Campylobacter pylori)
Length = 329
Score = 63.3 bits (147), Expect = 2e-08
Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 19/190 (10%)
Query: 107 LGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKR 166
+G L + G + ++ + ++ ALE GIN FD +EA+ E LG +K
Sbjct: 11 VGALALGCMGMTYGYGEVHDKKQMVKLIHKALELGINFFDTAEAYGEDNEKLLGEAIKPF 70
Query: 167 NVRRTSIIITTK--IYWSTKFHTNNRSDERGL--SRKHVIESVKASLGRLQVEYIDVVLL 222
+ +++ +K IY++ N++ L S + +++ SL RL+VE ID+
Sbjct: 71 ---KDKVVVASKFGIYYADP---NDKYATMFLDSSPNRIKSAIEGSLKRLKVECIDLYYQ 124
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI-VEQTE 281
H++D P+ E+ VM +I EG + WG + S I A+ C P+ Q+E
Sbjct: 125 HRMDTNTPIGEVAEVMQLLIKEGKIKAWGMSEAGLSSIQKAHQIC-------PLSALQSE 177
Query: 282 YHMFCREKPE 291
Y ++ RE PE
Sbjct: 178 YSLWWRE-PE 186
>UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothrix
orenii H 168|Rep: Aldo/keto reductase - Halothermothrix
orenii H 168
Length = 312
Score = 63.3 bits (147), Expect = 2e-08
Identities = 52/177 (29%), Positives = 90/177 (50%), Gaps = 23/177 (12%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---------LSEESIEDVVMTALENGINLFDLSEAHC 152
L+ + LG +GL V IG G W + E++I +V A+E G N FD + +
Sbjct: 2 LKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIR-LVHKAIEMGCNFFDTAPNYA 60
Query: 153 A-KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
K E LG+ LK + R +II++K + T S + L +K SV+ SLGR
Sbjct: 61 GGKSEELLGKALKGK---RDKVIISSKFGHTPDGQT---SFDPSLLKK----SVEESLGR 110
Query: 212 LQVEYIDVVLLHK--VDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTN 266
L+ +Y+D++LLH V+ + + ++M + EG + ++G + + +++D N
Sbjct: 111 LETDYLDILLLHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQMLDVINN 167
>UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothece
sp. CCY 0110|Rep: Putative oxidoreductase - Cyanothece
sp. CCY 0110
Length = 321
Score = 62.9 bits (146), Expect = 2e-08
Identities = 48/174 (27%), Positives = 86/174 (49%), Gaps = 18/174 (10%)
Query: 107 LGKSGLRVPNIGLGLWTMLSEESIED---VVMTALENGINLFDLSEAH---CAKG----- 155
L +G+ V + LG + ++ E+ V+ +E G N D + A+ C +G
Sbjct: 7 LSHTGVEVSCLCLGTLRFGTRKTYEESAKVMDMYIEAGGNFIDTANAYDQWCEQGKGGES 66
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
E +GR L++R R I + TK+ F N D GL+ +I ++SL RL V+
Sbjct: 67 EITIGRWLRERG-NRQDIFLATKV----GFGYQNVPD--GLAASTIISECESSLRRLGVD 119
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
+ID+ H DP P+EE ++ ++ +G + ++G + + P + DA C++
Sbjct: 120 HIDLYYAHHDDPHTPLEETLKAFEKLVQDGKIRFYGASNYLPWRLADADAICQR 173
>UniRef50_Q9HI90 Cluster: NDP-hexose 2, 3-enoyl reductase TylCII
related protein; n=2; Thermoplasma|Rep: NDP-hexose 2,
3-enoyl reductase TylCII related protein - Thermoplasma
acidophilum
Length = 343
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/127 (30%), Positives = 72/127 (56%), Gaps = 10/127 (7%)
Query: 125 LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWS 182
+++E + +V A + GINL+D ++ + +G++E LG+ LK R ++I TK+
Sbjct: 38 VTQELSDKMVKAAFDAGINLYDTADVY-DEGDSEIMLGKSLKPY---RDQVMIATKV--- 90
Query: 183 TKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVI 242
+ T N +E GLSR H+ +++ SL RL ++ID+ H D +E + M + +
Sbjct: 91 -RGRTGNGINESGLSRHHMSIAIRKSLERLDTKWIDIYQYHGWDLHGEFDEFLSTMEHFV 149
Query: 243 NEGWVMY 249
+ G+V+Y
Sbjct: 150 DSGYVIY 156
Score = 44.4 bits (100), Expect = 0.008
Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
D + ++ N+A C+MSQ A+AW + V ++GA ++EQ +EN+ ++ V +KK
Sbjct: 255 DIVDEVRNIAQEQGCTMSQAALAWIVSKGHV--AIIGARNMEQLQENLESINVNLKK 309
>UniRef50_A7D4B7 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 337
Score = 62.9 bits (146), Expect = 2e-08
Identities = 47/164 (28%), Positives = 79/164 (48%), Gaps = 18/164 (10%)
Query: 107 LGKSGLRVPNIGLGLW-----TMLSEESIEDVVMTALENGINL-----FDLSEAHCAKGE 156
LG++GLR LG W T I++ L +G D ++ + G+
Sbjct: 15 LGRTGLRTNEFQLGTWRFGRVTEAGNVEIDEARAHELLDGYEAAGGRYIDTADVY-GGGD 73
Query: 157 AE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E +G L +R+ R +I +K+YW + + + RG +RK+V V A L RL
Sbjct: 74 CERWIGDWLAERDRERYTI--ASKVYWQIR---DGDPNSRGTNRKNVRHRVDALLDRLDT 128
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPS 258
+Y+DV+ +H+ D P EL++ +N ++ G V Y G + P+
Sbjct: 129 DYLDVLYIHRWDDETPARELMKTLNGLVESGKVHYLGASTLRPN 172
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 62.9 bits (146), Expect = 2e-08
Identities = 44/118 (37%), Positives = 70/118 (59%), Gaps = 21/118 (17%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRIL----KK 165
SG +P IGLGLW L ++ +++V++ A++ G FD + AH K EA++G L K
Sbjct: 8 SGYEMPVIGLGLWR-LEKDELKEVILNAIKIGYRHFDCA-AHY-KSEADVGEALAEAFKT 64
Query: 166 RNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
V+R + ITTKI W++ + G HV+E+ K SL +LQ++Y+D+ L+H
Sbjct: 65 GLVKREELFITTKI-WNS---------DHG----HVVEACKNSLEKLQIDYLDLYLVH 108
>UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1;
Propionibacterium acnes|Rep: Putative oxidoreductase -
Propionibacterium acnes
Length = 324
Score = 62.5 bits (145), Expect = 3e-08
Identities = 52/207 (25%), Positives = 90/207 (43%), Gaps = 10/207 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT---MLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
+R + +G SGL+V IGLG T + +V ++ G NL D + A+ +
Sbjct: 3 MRMRTVGASGLKVSAIGLGSLTWGGQTDAREVRSLVRRFVDAGGNLVDTAPAYGGGFAEQ 62
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
L L ++ R ++I TK + + H SR ++ ++ SL RL +++D
Sbjct: 63 LIGKLTHTDISRDDLVIATKAGFIVEGHKRIVD----TSRSALLRDLEGSLRRLHTDHVD 118
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIV- 277
+ +H P+EE +++ + G Y G + + + A T R TP+V
Sbjct: 119 LWQVHAWGD-APIEETCAALDHAVTSGMARYVGVSNFVGWQAATAATWQRATGTRTPLVS 177
Query: 278 EQTEYHMFCREKPELYMPELYHKIGVG 304
Q EY + R +P H G+G
Sbjct: 178 NQVEYSLLARRAEIEVVPSAQHH-GMG 203
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 62.5 bits (145), Expect = 3e-08
Identities = 48/147 (32%), Positives = 69/147 (46%), Gaps = 25/147 (17%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
SG +P IGLG W E +E+ V AL G D A C + E E+G KK V
Sbjct: 11 SGYNIPAIGLGTWLSKPHE-VENAVEAALRAGYRHIDA--AACYQNENEVGNGWKKSGVP 67
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH------ 223
R I IT+K+ W+T H +HV E+V +L LQ +Y+D+ L+H
Sbjct: 68 RDQIFITSKL-WNTHHHP-----------EHVEEAVNKTLKDLQTDYLDLYLIHWPVAFE 115
Query: 224 ----KVDPVCPMEELVRVMNYVINEGW 246
+ P+ P+ + R+ N I + W
Sbjct: 116 HTNETLTPIDPVTKRFRLANVPIADTW 142
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 62.5 bits (145), Expect = 3e-08
Identities = 46/150 (30%), Positives = 77/150 (51%), Gaps = 13/150 (8%)
Query: 114 VPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSI 173
VP +G G + + + V AL+ G D + A+ + EA +GR +++ +V R I
Sbjct: 20 VPTLGFGTYRTGGYKCY-NAVKNALDCGYTHIDTAMAY--ENEAAVGRAIEQSSVDREDI 76
Query: 174 IITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEE 233
+TTKI K + ER +IE+ K L RL EY+D++L+H +P+ MEE
Sbjct: 77 FLTTKI----KGYPEMVEYER------LIEAAKGCLERLGTEYLDLLLVHWWNPLADMEE 126
Query: 234 LVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
+N ++++G V G + +S E+ A
Sbjct: 127 TFNALNTLVDDGLVGQIGVSNFSIKELKQA 156
>UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2;
Thermoprotei|Rep: Aldo/keto reductase - Thermofilum
pendens (strain Hrk 5)
Length = 322
Score = 62.5 bits (145), Expect = 3e-08
Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 26/174 (14%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT------MLSEESIEDVVMTALENGINLFDLSEAH-CAK 154
+ Y LGK+G +V IGLG W + E + VV ALE GIN FD + +
Sbjct: 1 MEYTVLGKTGEKVSRIGLGAWEFSEAWGLTDYEKAKSVVKRALELGINFFDTAMVYGNGF 60
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E LG L++ +R II++TKI +F L+ + +V+ S+ L +
Sbjct: 61 SEKTLGSALRELGAKRDEIIVSTKI--PGEF----------LNPLDIPRAVEHSVKLLGL 108
Query: 215 EYIDVVLLHKVDPVC----PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
Y+DV+L H P C P + R M ++N G V Y G + + P E+++++
Sbjct: 109 GYVDVLLAHW--PPCWHNYPTKVYARAMEQLVNVGLVRYLGLSNF-PVELVESF 159
>UniRef50_A4III4 Cluster: Kcnab2 protein; n=2; Euteleostomi|Rep:
Kcnab2 protein - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 145
Score = 62.1 bits (144), Expect = 4e-08
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 80 VTRHMSTYMGNHTAM---PSAVTPGLRYKNLGKSGLRVPNIGLGLWT----MLSEESIED 132
+ R + T+ H +A G++Y+NLGKSGLRV +GLG W +S+E E
Sbjct: 45 IARSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAEQ 104
Query: 133 VVMTALENGINLFDLSEAHCA 153
++ A ENG+NLFD +E + A
Sbjct: 105 LMTIAYENGVNLFDTAEVYAA 125
>UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus
plantarum|Rep: Oxidoreductase - Lactobacillus plantarum
Length = 264
Score = 62.1 bits (144), Expect = 4e-08
Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 18/152 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEES----IEDVVMTALENGINLFDLSEAHC-AKGE 156
L + +GK+GL++P + LGLW +E+ VV+ A ++G+ FDL+ + +KG
Sbjct: 14 LPIRRVGKTGLQLPVVSLGLWRNFGDEAPFANSRKVVLDAFDHGVFSFDLANNYGPSKGS 73
Query: 157 AE--LGRILKKR-NVRRTSIIITTKI---YWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
AE G+I+++ R ++ITTK WS + SRK +I S+ SL
Sbjct: 74 AERTFGQIMQRDLKPYRDELVITTKAGYPAWSGPYGAFG-------SRKTLISSLDRSLK 126
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVI 242
++ ++Y+D+ H+ DP + E ++ ++
Sbjct: 127 QMHLDYVDIFYSHRPDPNIDLYETAAALDQLV 158
Score = 36.3 bits (80), Expect = 2.0
Identities = 14/50 (28%), Positives = 31/50 (62%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHA 467
++L L +A +++Q+A+AW L+++ V +++G T+V+ N+ A
Sbjct: 196 NQLNALNRIAEQRGQTLAQMALAWLLRSQVVTSVIIGTTNVDHLHANLEA 245
>UniRef50_Q1FMI0 Cluster: Aldo/keto reductase; n=1; Clostridium
phytofermentans ISDg|Rep: Aldo/keto reductase -
Clostridium phytofermentans ISDg
Length = 337
Score = 62.1 bits (144), Expect = 4e-08
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 13/153 (8%)
Query: 112 LRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAHCA------KGEAELGRI 162
L+V NI LG L+EE + V+ + G N D ++ +C+ E LGR
Sbjct: 11 LKVSNICLGAGNFGDKLNEEEVYQVLDAFVSAGGNFIDTAKVYCSWATGDNSSEQYLGRW 70
Query: 163 LKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
LK RN + +++I TK F+ ++ + +SR+ + ++ SL L ++ I + L
Sbjct: 71 LKLRNAYQ-NVMIATK---GGHFYIGDKEKKSRVSRQEIATDLEESLQTLGLDCIGMYYL 126
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARW 255
H+ D + P+EE+V + EG + Y+ + W
Sbjct: 127 HRDDKLLPVEEIVDFCEDFVKEGKIRYYAFSNW 159
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 62.1 bits (144), Expect = 4e-08
Identities = 45/156 (28%), Positives = 82/156 (52%), Gaps = 16/156 (10%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G+ +P +GLG W M +E+ + V TA+E G L D +E + K E +G+ ++ V
Sbjct: 14 NGVEMPQLGLGTWPMTDDEAAK-AVATAIETGYRLIDTAENY--KNETGVGQGIRDAGVA 70
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDP-V 228
R + +TTK+ + ++H+ + G R + +ASL RL ++YID+ L+H +P
Sbjct: 71 RDEVFLTTKM--NKQWHSVD-----GARR-----ACEASLERLGLDYIDLFLIHWPNPDQ 118
Query: 229 CPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
E + +++ G V GT+ + P + D +
Sbjct: 119 GTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLF 154
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 62.1 bits (144), Expect = 4e-08
Identities = 47/179 (26%), Positives = 90/179 (50%), Gaps = 21/179 (11%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G ++P GLG++ + E EDV + AL+NG + D ++ + + E E+G ++K ++R
Sbjct: 18 GRKMPLFGLGVFRL--ETGCEDVCLFALKNGYRMLDTADIY--QNEKEVGSAVRKSGLKR 73
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCP 230
I +TTK+ S + H+N + K+ ES+K +L + Y+D+ L+H P
Sbjct: 74 EDIYVTTKLKPSEEGHSN--------ALKYAKESIK----KLDIGYVDLFLIHTPRPGNI 121
Query: 231 MEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ ++ + EG + G + + + + R+ C TP + Q E + F R++
Sbjct: 122 IAAYDALLT-LKEEGLIRSVGVSNFGVHHLEE----LRKAGCRTPAINQIEINPFWRQE 175
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 62.1 bits (144), Expect = 4e-08
Identities = 60/218 (27%), Positives = 100/218 (45%), Gaps = 35/218 (16%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+GL++P IGLG W E++ +TAL+NG D + A+ E ++GR + V
Sbjct: 16 NGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAY--GNEDQVGRAIADSGVS 73
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH---KVD 226
R I +TTK+ W+ + D G ++ SL +L +EY+D+ L+H VD
Sbjct: 74 RDEIFVTTKL-WN-----DQHKDPEG--------ALDESLKKLGLEYVDLYLIHWPLSVD 119
Query: 227 PVC--PME-----ELVRVMNYVINEG-WVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
P P + + R + + EG V G + ++ + +D N N + P++
Sbjct: 120 PKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKK-LDKLLNSEGVN-VVPVIN 177
Query: 279 QTEYHMFCREKPELYMPELYHKIGVGKIYILFFIQLNY 316
Q E H P L P+L+ + IYI + L +
Sbjct: 178 QIEAH------PLLTQPDLFDYLKSKDIYITAYSPLGH 209
>UniRef50_O34185 Cluster: Oxidoreductase; n=2; Halobacteriaceae|Rep:
Oxidoreductase - Halobacterium volcanii (Haloferax
volcanii)
Length = 336
Score = 62.1 bits (144), Expect = 4e-08
Identities = 57/216 (26%), Positives = 96/216 (44%), Gaps = 21/216 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAK------- 154
L + G++GL+ + G W +E+ + V E L D EA +
Sbjct: 9 LDFVPFGQTGLQTSELQFGTWRF-GKETEQGNVEIDEERAHELLDAYEAAGGRFIDTADI 67
Query: 155 ---GEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
G +E +G L+ R+ R I +KIYW + + + RG +RK+V + A L
Sbjct: 68 YGGGASERWIGDWLEDRD--RERFTIASKIYWQIR---DGDPNSRGTNRKNVRHRIDALL 122
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTN--C 267
RL +Y+DV+ +H+ D P E+++ +N ++ +G V Y G + P+ A N
Sbjct: 123 DRLDTDYVDVLYIHRWDDETPTREMMKTLNGLVEDGKVHYLGASTLRPNAWKVARANEIA 182
Query: 268 RQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
R V Q Y++ RE Y+ E+ G+
Sbjct: 183 RAEGWEPFTVAQPRYNLVDREIEGDYL-EMTRSYGI 217
Score = 37.5 bits (83), Expect = 0.87
Identities = 23/93 (24%), Positives = 42/93 (45%)
Query: 378 SRFNRKYSTFSWCEEDLAVPEMRSSGSKEQVTGEEPRTYGDKLRDLANLANSLNCSMSQL 437
S + + T + ED E R++ S D +L +A ++ + +Q
Sbjct: 223 SPLGQGFLTGKYTREDGLTGESRAAESSRFEESYLTEENFDVHDELDAVAGEVDATPAQT 282
Query: 438 AVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
A+AW + + V ++GA +VEQ EN+ A +
Sbjct: 283 ALAWLMHRDGVTAPIVGARTVEQLTENLEAATI 315
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 61.7 bits (143), Expect = 5e-08
Identities = 50/198 (25%), Positives = 95/198 (47%), Gaps = 23/198 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALEN-GINLFDLSEAHCAKGEAELG 160
++Y L +GL +P IGLG++ E+ E+ ++ A+++ G + D ++ + E +G
Sbjct: 1 MKYIKLA-NGLHMPIIGLGVYKA-EGENCENTIIKAIDDYGYRMIDTAQVYF--NEEFVG 56
Query: 161 RILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVV 220
+K+ ++R I ITTK+ W + + NN + S+ SL +LQ YID+V
Sbjct: 57 NAIKQTKIKREDIFITTKV-WISNYGYNN-----------TMYSISKSLKKLQTNYIDLV 104
Query: 221 LLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQT 280
LLH+ P + + + +G V G + + ++D C + + P++ Q
Sbjct: 105 LLHQ--PFGDYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDF---CLHVD-VKPVINQI 158
Query: 281 EYHMFCREKPELYMPELY 298
E H + +L+ Y
Sbjct: 159 ELHPLRQRIEDLHWNNKY 176
>UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 317
Score = 61.7 bits (143), Expect = 5e-08
Identities = 41/162 (25%), Positives = 84/162 (51%), Gaps = 9/162 (5%)
Query: 107 LGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRI 162
+G S L+ + LG+ M L ++ +V+ T + G+N D ++ + G++E G+
Sbjct: 6 IGASQLKASAVALGIMRMVRLDTDAAANVLETVHDRGVNFIDSADIY-GNGDSERIFGQA 64
Query: 163 LKKRNVRRTSIIITTK---IYWSTKFHTNNRSDER-GLSRKHVIESVKASLGRLQVEYID 218
LK+ +++R I +K + K +R S++H+I +V L R+Q++Y+D
Sbjct: 65 LKQSSLKREDFFIQSKGGIVLDPEKSSGELVFGQRYDFSKQHLIATVDKILQRMQLDYLD 124
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
LLH+ DP+ E+ + + G V ++G + ++P ++
Sbjct: 125 SFLLHRPDPLMDPAEVAAAFDELQATGKVRHFGVSNFNPMQV 166
>UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14;
Proteobacteria|Rep: Aldo/keto reductase - Marinomonas
sp. MWYL1
Length = 350
Score = 61.7 bits (143), Expect = 5e-08
Identities = 46/133 (34%), Positives = 68/133 (51%), Gaps = 14/133 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGL--WTMLSEESIEDV-VMTALENGINLFDLSEAHCA----- 153
++Y LG++GL V + LG W + ++ DV + AL NG+N D +E +
Sbjct: 1 MKYVPLGRTGLEVSRVCLGTMTWGTQNNQADADVQIEYALANGVNFIDTAEMYSVPPTPE 60
Query: 154 ---KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
K E +G L + RR I+ TKI + + S+ +S K VIE+V ASL
Sbjct: 61 SYGKTETIIGDWLSRNPSRREEFILATKIAGPGMKYVRDGSN---ISGKTVIEAVDASLK 117
Query: 211 RLQVEYIDVVLLH 223
RLQ +YID+ LH
Sbjct: 118 RLQTDYIDLYQLH 130
Score = 39.5 bits (88), Expect = 0.22
Identities = 16/40 (40%), Positives = 29/40 (72%)
Query: 435 SQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
+QLA+AWC + + V+ ++GATS+EQ KE++ A + + +
Sbjct: 294 AQLALAWCDQVDGVSSTIIGATSLEQLKEDMAAFDMTLSE 333
>UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=23;
Bacteria|Rep: Uncharacterized oxidoreductase ydjG -
Escherichia coli (strain K12)
Length = 326
Score = 61.7 bits (143), Expect = 5e-08
Identities = 52/175 (29%), Positives = 82/175 (46%), Gaps = 21/175 (12%)
Query: 107 LGKSGLRVPNIGLGLWTM---------LSEESIEDVVMTALENGINLFDLSEAH-CAKGE 156
LG + + + +GLG W + L + D ++ A GINL D + + E
Sbjct: 6 LGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSE 65
Query: 157 AELGRILKKRNVRRTSIIITTK--IYWSTKFHTNNRSDER----GLSRKHVIESVKASLG 210
+G+ LKK + R +++ TK I W K N+ +R LS + + E V ASL
Sbjct: 66 VIVGQALKK--LPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQ 123
Query: 211 RLQVEYIDVVLLH--KVDP-VCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
RL ++YID+ + H V P P+ E V V+N + +EG + G A I +
Sbjct: 124 RLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHIRE 178
Score = 41.9 bits (94), Expect = 0.041
Identities = 20/53 (37%), Positives = 29/53 (54%)
Query: 418 DKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
D L L C++ LA+AW LK + +L GAT+ EQ +EN+ AL +
Sbjct: 255 DMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNI 307
>UniRef50_Q4TA27 Cluster: Chromosome undetermined SCAF7470, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7470,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 381
Score = 61.3 bits (142), Expect = 6e-08
Identities = 28/66 (42%), Positives = 44/66 (66%)
Query: 405 KEQVTGEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKEN 464
KE++ +E + K+R+L LA L CS QLA+AWCL++E V+ +LLG ++ EQ EN
Sbjct: 291 KERLHSDEGKQQLSKIRELHLLAARLKCSAPQLAIAWCLRSEGVSSVLLGVSNTEQLMEN 350
Query: 465 IHALQV 470
+ ++ V
Sbjct: 351 LGSIGV 356
>UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=11;
Bacteria|Rep: Aldo/keto reductase family protein -
Leptospira interrogans
Length = 355
Score = 61.3 bits (142), Expect = 6e-08
Identities = 51/181 (28%), Positives = 90/181 (49%), Gaps = 11/181 (6%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE-ESIED--VVMTALENGINLFDLSEAHCAKGEA- 157
L+ + LGKSG+ V I +G T S + +E ++ A + GI+ +D +E + +A
Sbjct: 18 LKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAGIDFYDTAEVYPVPPDAS 77
Query: 158 ---ELGRILKK--RNVRRTSIIITTKIYWSTK--FHTNNRSDERGLSRKHVIESVKASLG 210
E RI K + +R SI+I TK+ F R + L RK++ +++ SL
Sbjct: 78 YVHETERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGKTALDRKNIRTAIEGSLR 137
Query: 211 RLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQF 270
RL +++D+ H D EE ++V+ +I EG V Y G + + +M + + +F
Sbjct: 138 RLGTDFVDLYQTHWPDHDFGYEETLQVLTELIKEGKVRYIGNSNETAWGMMKSLSISEKF 197
Query: 271 N 271
+
Sbjct: 198 S 198
Score = 37.1 bits (82), Expect = 1.2
Identities = 17/52 (32%), Positives = 31/52 (59%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYIKK 474
L +A S++ LAVAW +++ V ++GA +VEQ +E++ A V + +
Sbjct: 286 LMKIAQEAGMSVTVLAVAWSKQHDYVASTIIGANTVEQLEESLKAKNVILSE 337
>UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3;
Bacteria|Rep: Putative oxidoreductase - Mycoplasma
penetrans
Length = 343
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/192 (24%), Positives = 96/192 (50%), Gaps = 11/192 (5%)
Query: 107 LGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRILK 164
LG G G+ W +L + ++++ AL+ GIN FD + + A+G +E LGR ++
Sbjct: 18 LGCMGFGDNKSGVHKW-ILDYQQTKEIIKLALDKGINFFDTAPVY-AEGTSEEFLGRAIQ 75
Query: 165 KRNVRRTSIIITTKIYWSTKFHTNNRSDERGLS-RKHVIESVKASLGRLQVEYIDVVLLH 223
+ +R +++I TK F + + E+G++ ++ V ++++ SL RL +Y+D+ +LH
Sbjct: 76 ELT-KRENVVIATKF-----FPRSREAYEKGITGQQWVQQNLEQSLKRLNTDYVDLYILH 129
Query: 224 KVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYH 283
D P+E+++ +N + V G + ++ A + + Q Y+
Sbjct: 130 LWDYNTPIEDILEGLNNAVKSKKVRAIGISNCYAWQLQKANDIAKANGWSQFVSIQGHYN 189
Query: 284 MFCREKPELYMP 295
+ RE+ +P
Sbjct: 190 LIFREEEREMIP 201
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 15/154 (9%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G R+P IGLG W LS VV AL G D ++ + E E+G ++ VR
Sbjct: 7 NGARIPAIGLGTWE-LSGRPCARVVEQALRLGYRHIDTAQVY--DNEREVGDGVRASGVR 63
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R + +TTK+ W+ F N+ L R SVK SL RL++ +D++LLH +
Sbjct: 64 RDDVFLTTKV-WTNHFAPND------LER-----SVKESLARLRLPSVDLLLLHWPNSHV 111
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
P+ E + +++ G + G + ++ + I A
Sbjct: 112 PLAETLGALSHARQMGLTRHIGVSNFTVALIEQA 145
>UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Marinomonas sp. MWYL1
Length = 326
Score = 61.3 bits (142), Expect = 6e-08
Identities = 60/212 (28%), Positives = 105/212 (49%), Gaps = 22/212 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE-ESIED-----VVMTALENGINLFDLSEAHCAKG 155
++ + LGK+G V IGLG W + ++ +ED ++ TA++ GI +D ++ + G
Sbjct: 1 MKTRTLGKTGFEVSEIGLGCWQLGNDFGPVEDNEAIAILQTAVDEGIRFYDTADVY--GG 58
Query: 156 EAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
RI + R + S +I TK+ S + + N G S+ V +S++AS RL VE
Sbjct: 59 GLSEQRIGQWRKSLKKSPVIATKVGRSAELYPN------GYSKAAVKKSLQASAQRLGVE 112
Query: 216 YIDVVLLHKVD-PVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
ID+ LH V V +++ M + EG + ++G + E++D C +
Sbjct: 113 SIDLAQLHCVPREVLFSGDILAWMEDLKTEGVIKHFGAS----VEMLDEAMFCCGHTELA 168
Query: 275 PIVEQTEYHMFCREKPELYMPELYHKIGVGKI 306
+ Q +++F ++ E +P L K GVG I
Sbjct: 169 SL--QILFNVFRQDATESLLP-LAEKNGVGII 197
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 61.3 bits (142), Expect = 6e-08
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 22/180 (12%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G+ +P IG+G+WT+ E++ E V AL+ G L D + + + E +GR ++ +
Sbjct: 49 NGIEMPIIGIGVWTLTPEQT-EKSVGEALKAGYRLIDTARMY--RNEQAVGRAVRDSGIP 105
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R I ITTKIY S + + ++ L L +YID++LLH D
Sbjct: 106 REEIFITTKIYGSGDY-------------ANAEAAINERLRLLDTDYIDLLLLHYPDQ-- 150
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ +VM + G + G + + + Q ITP V Q E H++ ++K
Sbjct: 151 NDTKAWKVMEQFVKAGKIRAIGLSNYH----RKTFNRIMQAATITPAVVQNEVHIYNQDK 206
>UniRef50_A4WGJ6 Cluster: Aldo/keto reductase precursor; n=4;
Bacteria|Rep: Aldo/keto reductase precursor -
Enterobacter sp. 638
Length = 390
Score = 61.3 bits (142), Expect = 6e-08
Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 16/172 (9%)
Query: 134 VMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDE 193
+ A G+ LFD +E + EL V + +++ ++KF + +
Sbjct: 101 IREAHARGVTLFDTAEVYGPYTNEEL--------VGEALAPVRNQVFIASKFGFDIQHGG 152
Query: 194 RGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
KH+ + ++ASL RL+ + ID+ H+VDP P+E++ + +I EG V+++G +
Sbjct: 153 LNSQPKHIRKVLEASLRRLRTDRIDLYYQHRVDPGVPIEDVAGTIQDLIKEGKVLHFGLS 212
Query: 254 RWSPSEIMDAYTNCRQFNCITPIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
SPS I Q + I P+ QTEY + R+ + + ++G+G
Sbjct: 213 EASPSTI-------HQAHAIQPVTAVQTEYSVMNRDPEHNGVLDTCEELGIG 257
>UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=5; Flavobacteriales|Rep: Oxidoreductase,
aldo/keto reductase family protein - Croceibacter
atlanticus HTCC2559
Length = 293
Score = 61.3 bits (142), Expect = 6e-08
Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 4/145 (2%)
Query: 120 GLW-TMLSEESIEDVVMTALENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITT 177
G W +S + + + + L+ GI FD ++ + EAE G+ K+ V R + + +
Sbjct: 19 GAWGAKMSTQQMAEQIEHVLDLGITTFDHADIYGGYTTEAEFGKAFKESGVNREDVQLIS 78
Query: 178 K--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELV 235
K I + + NR +++E+ + SL +L Y+D++LLH+ P+ E+
Sbjct: 79 KLGIQYLSDERPYNRVKHYQYDATYILENTERSLQKLNTNYLDLLLLHRPSPLMDPLEIK 138
Query: 236 RVMNYVINEGWVMYWGTARWSPSEI 260
+ ++ EG + +G + ++PS++
Sbjct: 139 GAIERLLTEGKIKSFGVSNFTPSQV 163
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 61.3 bits (142), Expect = 6e-08
Identities = 39/144 (27%), Positives = 74/144 (51%), Gaps = 15/144 (10%)
Query: 113 RVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTS 172
+ P++G G + L ++++ D+V AL G D ++A+ + E ++G L++ +VRR
Sbjct: 10 QTPSLGFGTF-QLEQDTVADMVAAALSEGFRHIDTAQAY--QNEEQVGEGLRRADVRRDE 66
Query: 173 IIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPME 232
+ +TTKI S + + ASL RL +Y+D++LLH P+
Sbjct: 67 VFLTTKIL------------PEHFSPEAFTAAADASLKRLGTDYVDLLLLHWPSKEVPIA 114
Query: 233 ELVRVMNYVINEGWVMYWGTARWS 256
E + +N +I+ G V + G + ++
Sbjct: 115 ETIGALNDLISAGKVRHGGVSNFT 138
>UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4;
Thermoproteaceae|Rep: Aldo-keto reductase, putative -
Pyrobaculum aerophilum
Length = 317
Score = 61.3 bits (142), Expect = 6e-08
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 32/204 (15%)
Query: 107 LGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE- 158
LG++ +RV IGLG W ++ E + VV ALE GIN FD + + +G +E
Sbjct: 6 LGRTDMRVSRIGLGAWQFSGDAWGAITYEQAKAVVSKALEVGINFFDTAAVY-GRGRSEE 64
Query: 159 -LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
LGR +++ R +Y +TK H + L R ++ SV+ RL V+ I
Sbjct: 65 FLGRAIRELGAR-------DHVYIATKIHGD------WLRRIDILTSVENQRRRLGVDAI 111
Query: 218 DVVLLHKVDPVC----PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCI 273
D+ +H P C P+ E ++ + +++ G V Y G + + P +++ +C + +
Sbjct: 112 DLYQIHW--PACWHNTPICETMKTLEELVDRGLVRYIGVSNF-PLALLERARSC--LSRV 166
Query: 274 TPIVEQTEYHMFCREKPELYMPEL 297
+ Q Y++ RE + +P L
Sbjct: 167 DIVTSQNRYNIIEREADKELLPYL 190
>UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp.
CcI3|Rep: Aldo/keto reductase - Frankia sp. (strain
CcI3)
Length = 322
Score = 60.9 bits (141), Expect = 8e-08
Identities = 49/172 (28%), Positives = 86/172 (50%), Gaps = 13/172 (7%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIED-----VVMTALENGINLFDLSEAHCA 153
++ + LG +G+ V IGLG M E ++D V+ A++ G+ L D ++ + A
Sbjct: 1 MQVRKLGATGVEVGGIGLGCMGMSWLYKESELDDNRSVEVIREAVDLGVTLLDTADIYGA 60
Query: 154 KGEAELGRILKKRNV-RRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
EL L + V RR +++ TK + RS G S ++ +++ASL RL
Sbjct: 61 GHNEEL---LGRAAVGRREDVVVATKFGIVIEDLAARRSHLDG-SPAYLRTAIEASLRRL 116
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
E ID+ LH+VD P+ + M ++ EG V + G + S ++ ++A+
Sbjct: 117 GTEVIDLYYLHRVDSAVPLADTWGAMAELVAEGKVRFLGLSEVSVAQAVEAH 168
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 60.9 bits (141), Expect = 8e-08
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 15/153 (9%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G +P +G G++ M S+ +E ++ ALE G FD ++ + + EA LGR L++ RR
Sbjct: 8 GATIPALGFGVFRM-SDAEVERIIPAALEAGFRHFDTAQIY--QNEAALGRALERAGARR 64
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCP 230
+ +TTK++ +N S ++ SV SL +L+V+ +D++LLH P
Sbjct: 65 EDLFLTTKVW------VDNYSADK------FAASVDESLEKLKVDQVDLLLLHWPAHEVP 112
Query: 231 MEELVRVMNYVINEGWVMYWGTARWSPSEIMDA 263
+ + +N V + G + G + + +++ ++
Sbjct: 113 VAAQIERLNAVKDAGKTRFIGVSNQNIAQMRES 145
>UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50;
Bacteria|Rep: Possible aldo/keto reductase - Rhodococcus
sp. (strain RHA1)
Length = 379
Score = 60.9 bits (141), Expect = 8e-08
Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 14/196 (7%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEE----SIEDVVMTALENGINLFDLSEAHCAKGEA-- 157
Y G SGL +P GLW + + ++++ A + GI FD ++ + A
Sbjct: 58 YHRTGNSGLDLPAFSFGLWQKFGSDYAFATQREIILHAFDLGITHFDNADRYGPPHRAAQ 117
Query: 158 -ELGRILKKRNVR-RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
G +L K R +I++TK +G SRK ++ S+ SL L +
Sbjct: 118 KNFGAVLAKDLAPYRDELILSTK----AGNPIGPSPYLKGGSRKSILTSLDHSLRDLGTD 173
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
Y+D+ H D P+EE V + + +G +Y G + + P +A RQ +
Sbjct: 174 YVDIFYHHSPDLSTPLEESVGALVSAVEQGKALYVGISNYLPDRTHEAAELLRQAG-VPL 232
Query: 276 IVEQTEYHMFCREKPE 291
++ Q Y ++ R +PE
Sbjct: 233 LIHQARYSIYDR-RPE 247
Score = 45.2 bits (102), Expect = 0.004
Identities = 21/54 (38%), Positives = 32/54 (59%)
Query: 415 TYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHAL 468
TY + +L +A + S++QLA+ W L+ + V L+GA+S EQ NI AL
Sbjct: 301 TYRQRTAELNKIAEARGQSLAQLALQWVLRRQEVTSALIGASSTEQLDHNIAAL 354
>UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|Rep:
Aldo/keto reductase - Marinomonas sp. MWYL1
Length = 299
Score = 60.9 bits (141), Expect = 8e-08
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 10/161 (6%)
Query: 103 RYKNLGKSGLRVPN--IGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCA-KGEAEL 159
+Y LG G R+ L W + S E++ + + L+ G+ FD ++ + + EA
Sbjct: 4 QYHPLGFEGSRIAQGFWRLNEWNITSTEALS-FIESCLDLGVTTFDHADIYGGYQCEALF 62
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDER----GLSRKHVIESVKASLGRLQVE 215
G LK++ R + I TK + NR D + S +H++ SV SL LQ E
Sbjct: 63 GDALKQKPALRDKMEIITKC--GILLPSENRPDIQVHRYEYSAEHILASVDKSLANLQCE 120
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
YID +LLH+ P+ +E+ + + + G V ++G + ++
Sbjct: 121 YIDTLLLHRPSPLMDADEVAQAFDLLFTLGKVKHFGVSNFT 161
Score = 38.7 bits (86), Expect = 0.38
Identities = 15/48 (31%), Positives = 28/48 (58%)
Query: 423 LANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
L +L+ NCSM QL VAW L++ + C ++G+ + + + A+ +
Sbjct: 232 LKDLSGKYNCSMDQLVVAWLLRHPAGICPVMGSGKINRLVSAVEAISI 279
>UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n=1;
Pedobacter sp. BAL39|Rep: Putative Norsolorinic acid
reductase - Pedobacter sp. BAL39
Length = 323
Score = 60.9 bits (141), Expect = 8e-08
Identities = 41/132 (31%), Positives = 74/132 (56%), Gaps = 8/132 (6%)
Query: 126 SEESIEDVVMTALENGINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWST 183
S E IE ++ T + G N D+++ + GEAE +G+ L + R + II TK S+
Sbjct: 33 SPEEIEKILTTYTDAGGNFIDIADQY-QLGEAEEVIGKFLAGQ---RENFIICTKYTRSS 88
Query: 184 KFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVIN 243
+ + ++ G RK + + ++ASL RL+ +YID+ + H D P++E+VR + ++
Sbjct: 89 EKEPSFQNS--GNHRKAMRQGIEASLKRLKTDYIDIYMPHYDDGYTPIDEIVRGLEDLVK 146
Query: 244 EGWVMYWGTARW 255
G V++ G A +
Sbjct: 147 SGKVLFTGLANF 158
>UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Eukaryota|Rep: Oxidoreductase, aldo/keto
reductase family protein - Trichomonas vaginalis G3
Length = 286
Score = 60.9 bits (141), Expect = 8e-08
Identities = 48/186 (25%), Positives = 88/186 (47%), Gaps = 22/186 (11%)
Query: 106 NLGKSGLRVPNIGLGLWTMLSE----ESIEDVVMTALENGINLFDLSEAHCAKGEAELGR 161
N+ +G ++P IGLG W + E+ + V TA+ G+ L D +E + G
Sbjct: 8 NILSNGNKIPKIGLGCWNFGNPGCPLETEQSAVKTAVNGGMVLLDTAELY--------GD 59
Query: 162 ILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVL 221
L + ++ I K++ +K +N RK++ S + SL L +EY+D+ L
Sbjct: 60 GLSEEFLKDLIKPIREKLFIVSKVLPSNAG------RKNIFNSCEKSLQHLGIEYLDLYL 113
Query: 222 LHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTE 281
LH V P++E V M ++ +G + WG + + ++ + ++ +C +V Q
Sbjct: 114 LHWRGRV-PLKETVECMEELVKQGKIKQWGVSNFDVDDMKELWSIPNGDHC---VVNQVL 169
Query: 282 YHMFCR 287
YH+ R
Sbjct: 170 YHLGSR 175
>UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2;
Proteobacteria|Rep: Aldo/keto reductase - Delftia
acidovorans SPH-1
Length = 360
Score = 60.5 bits (140), Expect = 1e-07
Identities = 62/213 (29%), Positives = 101/213 (47%), Gaps = 22/213 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMT------ALENGINLFDLSEAHCAKG 155
++ + LG L+V +GLG M D + A+E+GI+ D ++ +
Sbjct: 34 MQQRTLGHD-LQVSALGLGCMGMSEFYGPRDDALALQALDHAVESGIDFLDTADVYGPHH 92
Query: 156 EAEL-GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
EL GR L R R + I TK K RS + S ++ +S + SL RL V
Sbjct: 93 NEELIGRFLASRRPR---VKIATKFGIVRKAGEYRRSIDN--SAQYARQSCEDSLRRLGV 147
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
E ID+ +H+VD P+EE ++ + ++ EG + AR E+ A R+ + +
Sbjct: 148 ERIDLYYVHRVDATRPIEETMQGLAQLVQEGKI-----ARIGLCEVSAA--TLRRAHAVH 200
Query: 275 PIVE-QTEYHMFCREKPELYMPELYHKIGVGKI 306
P+ QTEY ++ RE E +P ++GVG +
Sbjct: 201 PVAAVQTEYSLWTREVEEEVLPAC-RELGVGLV 232
>UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha
proteobacterium HTCC2255|Rep: Aldo/keto reductase -
alpha proteobacterium HTCC2255
Length = 327
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/171 (26%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLS------EESIEDVVMTALENGINLFDLSEAH-CAK 154
++ + LG GL V IG G ++ +++ + + +A +NGI+ FD ++ +
Sbjct: 1 MKIRKLGNEGLNVSAIGFGAMSITGFFGPTDDKTSQKCLASAYDNGIDFFDTADVYGSGS 60
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTK-FHTNNRSDERGLSRKHVIESVKASLGRLQ 213
E +G+ LK+ + I I TK T+ N S+E ++ +S+ SL RL
Sbjct: 61 SEKLIGQFLKETKAK---IKIATKSGIQTEPIRQFNNSNE------YLSDSLDKSLHRLG 111
Query: 214 VEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
V+Y+D+ +H+ + P+EE+V + I G + +G + SP+ + A+
Sbjct: 112 VDYVDLFYIHRREASRPIEEVVETLTGFIKSGKIGGYGLSEVSPTTLRRAH 162
>UniRef50_A6LCA8 Cluster: Aldo/keto reductase; n=3;
Bacteroidales|Rep: Aldo/keto reductase - Parabacteroides
distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 387
Score = 60.1 bits (139), Expect = 1e-07
Identities = 50/174 (28%), Positives = 87/174 (50%), Gaps = 14/174 (8%)
Query: 133 VVMTALENGINLFDLSEAHCAK-GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNR- 190
+V A++ G+ LFD +E++ + E +G LK + R + +TTK + KF +
Sbjct: 95 LVHEAIDRGVTLFDTAESYGYQTNERLVGEALKGYSDR---VFVTTK--FGHKFVDGVQI 149
Query: 191 SDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYW 250
E S ++ + + SL L VE + + H+ DP P+E + +N +I EG V+++
Sbjct: 150 KTEEDSSPNNIRKVCENSLRNLGVETLGMFYQHRADPNTPIEVVAETVNELIREGKVLHF 209
Query: 251 GTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
G + I A+ C +T I Q+EYH+ R E +P L ++G+G
Sbjct: 210 GLCEVNADTIRRAHRICP----VTAI--QSEYHLMHRAVEESVLP-LCEELGIG 256
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 60.1 bits (139), Expect = 1e-07
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 19/176 (10%)
Query: 114 VPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSI 173
+P +GLGL+ ED + A++NG L D + A+ K E +G + K V R +
Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAY--KNEEFVGCGIAKCGVPRKDL 58
Query: 174 IITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEE 233
ITTKI W+ + D G + + SL RL ++YID+ L+H P C +
Sbjct: 59 FITTKI-WN---NAQRLGDVEG--------AFQRSLDRLGLDYIDLYLIHWPVPGCFLNT 106
Query: 234 LVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ M ++ G + G + + + + R+ + I P V Q E H C K
Sbjct: 107 W-KDMEKILESGRALSIGVSNFEIRHLEE----LRRVSGIVPAVNQIECHPLCYPK 157
>UniRef50_A7Q5Z6 Cluster: Chromosome chr14 scaffold_54, whole genome
shotgun sequence; n=20; Magnoliophyta|Rep: Chromosome
chr14 scaffold_54, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 351
Score = 60.1 bits (139), Expect = 1e-07
Identities = 55/205 (26%), Positives = 94/205 (45%), Gaps = 19/205 (9%)
Query: 107 LGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGEAEL 159
LG GL V +G G + +SEE ++ A GI D S+ + E +
Sbjct: 16 LGNQGLEVSKLGFGCAGLFGVYDNPVSEELAVSIIKYAFSKGITFLDTSDFYGPNAELLV 75
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G++LK+ + R I + TK T+ + + ++V +A+L L V YID+
Sbjct: 76 GKVLKE--LPREKIQLATKFGLVRAEPTHMVVNG---TPEYVRSCCEATLKHLDVGYIDL 130
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQ 279
H++D P+EE + + ++ EG + Y G S I A+ + IT I +
Sbjct: 131 YYQHRIDTSIPIEETMGELKKLVEEGKIKYIGLCEASSDTIRRAHA----VHPITAI--E 184
Query: 280 TEYHMFCREKPELYMPELYHKIGVG 304
E+ ++ RE E +P L ++G+G
Sbjct: 185 MEWSLWTREIEEEILP-LCRELGIG 208
>UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella
pneumophila|Rep: Aldo/keto reductase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 336
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 18/195 (9%)
Query: 102 LRYKNLGKSGLRVPNIG---LGLWTMLSEESIEDVVMTALENG-----INLFDLSEAHC- 152
++Y+ LGK G V +G +GL + + D + + N +N FD ++ +
Sbjct: 1 MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGK 60
Query: 153 AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
K E +G+ +K R II+ TK + +N+ S ++ + + SL RL
Sbjct: 61 GKNEELVGKAIKPF---RNQIILATKC-GVVRTGSNDEMSVNN-SSAYIRTACEKSLKRL 115
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
++ID+ LH+ D P+EE++ +M+ +I+EG + Y G + I AYT +
Sbjct: 116 NTDHIDLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDADTIRAAYTAVKD--- 172
Query: 273 ITPIVEQTEYHMFCR 287
+ QTEY + R
Sbjct: 173 -KLVAVQTEYSLRVR 186
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 59.7 bits (138), Expect = 2e-07
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 21/186 (11%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G+++P +G G++ + + VV LE G L D ++ + E +G +K NV
Sbjct: 9 NGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIY--GNEQAVGDAIKHSNVP 66
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R I IT+KI W + +N +++ S+ +LQ++YID+ L+HK P
Sbjct: 67 REDIFITSKI-WVDDYGYDN-----------TLKAFDDSMKKLQLDYIDLYLIHK--PYN 112
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCRE- 288
R + + EG + G + + + D T FN + P V Q E +++ +E
Sbjct: 113 DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLIT----FNDVKPAVNQIETNVWNQEW 168
Query: 289 KPELYM 294
K + YM
Sbjct: 169 KSQQYM 174
>UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2;
Bacillus|Rep: Putative uncharacterized protein -
Bacillus sp. SG-1
Length = 307
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/198 (26%), Positives = 89/198 (44%), Gaps = 14/198 (7%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSE-ESIEDVVMTALENGINLFDLSEAH-CAKGEAELGRI 162
+ LG S L V +GLG ++ + + + ++ ALE GIN FD ++ + + E +G+
Sbjct: 4 RRLGNSDLHVSRMGLGCMSLGKDLKKAQPIIEAALEEGINYFDTADLYDFGENEQIVGKA 63
Query: 163 LKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
L + R +II TK ++ S+ ++ E+ K SL RL +YID+ L
Sbjct: 64 L---HSVRDKVIIATKA--GNRWDDVEDGWHWDPSKHYIKEAAKRSLKRLGTDYIDLYQL 118
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEY 282
H EE + + EG + Y+G + P+ I ++F+ + IV
Sbjct: 119 HGGTMEDHAEETIEAFEELKQEGIIRYYGISSIRPNVI-------KRFSESSNIVSVMMQ 171
Query: 283 HMFCREKPELYMPELYHK 300
+ +PE P L K
Sbjct: 172 YSLLDRRPEEVFPRLKEK 189
>UniRef50_A3YG17 Cluster: Oxidoreductase; n=1; Marinomonas sp.
MED121|Rep: Oxidoreductase - Marinomonas sp. MED121
Length = 342
Score = 59.7 bits (138), Expect = 2e-07
Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 11/188 (5%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTA---LENGINLFDLSEAHCAK-GEAEL 159
Y+ LG++G V + LG T +E + D + G D ++ + A E +
Sbjct: 3 YQQLGQNGPIVSRLALGTMTFGAETNEVDAFRQLDCFADYGGTFIDTADVYSAGLSEEII 62
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
GR +K+R I+ +TK + G SR+ +++SV+ASL RLQ+E IDV
Sbjct: 63 GRWIKQRGGLGQMIL-------ATKGRFAPPAGSYGGSRRAIVKSVEASLKRLQLESIDV 115
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQ 279
+H D +EE V + +I G + + + S +I + C + P+ Q
Sbjct: 116 YYMHGWDTQTDIEETVNTLGDLIRMGKIHHIAWSNVSGWQIQKIVSTCDKLGVSRPVSVQ 175
Query: 280 TEYHMFCR 287
+Y++ R
Sbjct: 176 PQYNLLDR 183
Score = 41.9 bits (94), Expect = 0.041
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 420 LRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQVYI--KKIFK 477
L L ++A MS +A+ W L +V+ LLLGA ++EQ ++N++++++ + K+I
Sbjct: 250 LDTLESIATQHQIPMSHVALTWLLSRPAVSTLLLGARTIEQLEDNLNSIRLVLESKEINA 309
Query: 478 VCVKSFKLLQQSPLRF 493
+ S L + P +F
Sbjct: 310 LTKVSAPGLPEYPYQF 325
>UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma
proteobacterium HTCC2143|Rep: Aldo/keto reductase -
marine gamma proteobacterium HTCC2143
Length = 345
Score = 59.7 bits (138), Expect = 2e-07
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 15/205 (7%)
Query: 107 LGKSGLRVPNIG-LGLWTMLSEESIEDVVMTALENGINLFDLSEAH-CAKGEAELGRILK 164
LG P G G WT+ E+ + + A++ G+ FD ++ + E +G +LK
Sbjct: 22 LGTMNFGQPGRGHQGDWTLGPNEA-KAIFSAAIDRGLFYFDCADIYGLGATEEVVGEVLK 80
Query: 165 KRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHK 224
+ R ++TTK+ + RGLSRKH++E + SL RL +Y+D +++H+
Sbjct: 81 GL-LPRDEYVLTTKV----SMPMGENPNLRGLSRKHIMEGIDKSLKRLGHDYVDQLVIHR 135
Query: 225 ------VDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
P+EE + +N V+ G +Y G + + + + I
Sbjct: 136 HPHGVPGHGDVPIEETMEALNDVVKAGKALYLGGSSMFAWQFAELQMTAEKNGWNKFISM 195
Query: 279 QTEYHMFCREKPELYMPELYHKIGV 303
Q Y++ RE+ E M K GV
Sbjct: 196 QNHYNLIYREE-EREMNPYCEKTGV 219
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 59.7 bits (138), Expect = 2e-07
Identities = 47/202 (23%), Positives = 97/202 (48%), Gaps = 31/202 (15%)
Query: 102 LRYKNLGKSGLRVPNIGLGL-----WTMLSEESIE-------DVVMTALENGINLFDLSE 149
+ YK G +G++V ++G+G W LS +++ + TA++ G+ L D +E
Sbjct: 8 MEYKEFGNTGVKVSSVGIGTYYDPGWMALSRFNVKRDAEKKIQAIRTAIDAGVTLIDTAE 67
Query: 150 AHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASL 209
+ + E + + ++ N R + I TK+ W R D+ VI++ KASL
Sbjct: 68 IYGS--EDLVAKAIEGHN--REELFIATKV-WINHL----RYDK-------VIKACKASL 111
Query: 210 GRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQ 269
RL +Y+D+ +H P ++E + M ++++G V + G + +S ++ + ++
Sbjct: 112 SRLNTKYVDLYQIHFPSPTANLQETFKAMEKLVDDGLVKFIGVSNFSRGKLEKSMEYVKK 171
Query: 270 FNCITPIVEQTEYHMFCREKPE 291
+ ++ Q Y + R+ E
Sbjct: 172 YEIVS---NQIHYSLKKRDAEE 190
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 59.3 bits (137), Expect = 2e-07
Identities = 44/172 (25%), Positives = 84/172 (48%), Gaps = 19/172 (11%)
Query: 114 VPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSI 173
+P +G G W + + ++ +V ALE G D ++ + E ++G ++ V+R I
Sbjct: 15 MPALGFGTWQLENGTAVP-LVEKALEIGYRHIDTAQIY--GNERDVGAAIRNSGVKRDEI 71
Query: 174 IITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEE 233
+TTK+ W +F + L R S + SL +L V+ +D++LLH P P+ E
Sbjct: 72 FLTTKV-WIDQFADGD------LQR-----SAEKSLEKLGVDQVDLLLLHWPKPEVPLAE 119
Query: 234 LVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMF 285
++ +N V +GW G + + +++ +A + + +Q EYH +
Sbjct: 120 TLKALNAVRAKGWTRAIGLSNFPSAQLEEA----AKLSEAPIATDQVEYHPY 167
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 59.3 bits (137), Expect = 2e-07
Identities = 53/189 (28%), Positives = 91/189 (48%), Gaps = 23/189 (12%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G ++P+IG G++ + EE+ D V A+ G L D ++A+ + E LG +K V+
Sbjct: 13 NGNKIPSIGFGVFQIPKEETA-DCVKKAISIGYRLIDTAQAYHNEKETGLG--IKLSGVK 69
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R I +TTK+ W + + + ESV SL RL Y+D++LLH+ P
Sbjct: 70 REEIFLTTKV-WVSNY-------------ERCYESVIESLKRLDTSYLDLILLHQ--PFG 113
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ + + + E V G + + + I+D C FN I P+V Q E + F +
Sbjct: 114 NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDL---C-FFNQIKPMVNQIEINPFHQRI 169
Query: 290 PELYMPELY 298
+ + + Y
Sbjct: 170 EDRFYNDKY 178
>UniRef50_Q03X89 Cluster: Aryl-alcohol dehydrogenase family enzyme;
n=6; Bacteria|Rep: Aryl-alcohol dehydrogenase family
enzyme - Leuconostoc mesenteroides subsp. mesenteroides
(strain ATCC 8293 /NCDO 523)
Length = 329
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 103 RYKNLGKSGLRVPNIGLGLWTML-------SEESIEDVVMTALENGINLFDLSEAHCA-K 154
R+ + V IGLG M E+S+ V+ A+E G + D +E +
Sbjct: 4 RFLGSDNHSIEVSTIGLGTMGMSFAYGHLPDEQSMIPVLQEAVEMGEHFIDTAEVYGPFT 63
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E+ +G+ L R ++I TK N + G + + S++ SL RL+V
Sbjct: 64 NESLIGKALYPY---RHDMVIATKGGIQI---VNGKQVIDGHPQT-LENSIEGSLKRLKV 116
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+ ID+ LH+VD P+EE+ M +I G + +WG + I R+ + IT
Sbjct: 117 DAIDLYYLHRVDTSVPIEEVADFMGRMIKAGKIKHWGLSEAGVQTI-------RKAHAIT 169
Query: 275 PIVE-QTEYHMFCREKPELYMPELYHKIGVG 304
P+ ++EY ++ RE E +P L ++G+G
Sbjct: 170 PLTAVESEYSLWYREPEEQLLPTL-KELGIG 199
>UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4;
Bacteria|Rep: Aldo/keto reductase precursor -
Acidiphilium cryptum (strain JF-5)
Length = 326
Score = 59.3 bits (137), Expect = 2e-07
Identities = 50/168 (29%), Positives = 83/168 (49%), Gaps = 11/168 (6%)
Query: 137 ALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGL 196
ALE GI FD ++ + L K N R+ I++ TK + +F + +
Sbjct: 40 ALERGITFFDSADMYGFGDNERLLSDFVKAN--RSRIVLATK--FGNEFTEDRQRVGING 95
Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
+V + ASL RL ++ ID+ H+VDP P+EE V M ++ G V + G + +
Sbjct: 96 RPDYVRRACDASLKRLGIDTIDLYYQHRVDPNVPIEETVGAMADLVKAGKVRHLGLSEAA 155
Query: 257 PSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGVG 304
P+ I A+ + + IT + QTEY ++ RE PE + ++G+G
Sbjct: 156 PATIRRAH----KVHPITAL--QTEYSLWSRE-PEGEILATVRELGIG 196
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 58.8 bits (136), Expect = 3e-07
Identities = 38/113 (33%), Positives = 63/113 (55%), Gaps = 15/113 (13%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G R+P +G+G W + EE V +A+E G L D +EA+ E +G+ +++ R
Sbjct: 16 GTRMPMLGMGTWPLKGEEC-RAAVASAIEQGYRLVDTAEAY--GNEEAVGKAVREAGPDR 72
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH 223
I +TTK +S ++H SRK V E+++ SL RL ++Y+D+ L+H
Sbjct: 73 AEIFVTTK--FSKQWH----------SRKGVHEALEHSLERLGLDYVDLFLMH 113
>UniRef50_A2QBJ9 Cluster: Remark: AFAR is a protein in rat liver
cytosol that reduces aflatoxin B1-dialdehyde; n=1;
Aspergillus niger|Rep: Remark: AFAR is a protein in rat
liver cytosol that reduces aflatoxin B1-dialdehyde -
Aspergillus niger
Length = 336
Score = 58.8 bits (136), Expect = 3e-07
Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 6/193 (3%)
Query: 112 LRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRT 171
+ V GL ++ I+ V+ ++G D S A+ AKG +E +L + +
Sbjct: 16 MTVGQAGLSGCRQTNQAEIKAVLDVFQKHGHTEVDTSRAY-AKGTSE--ELLGQSQWQNR 72
Query: 172 SIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPM 231
+ + TKIY + +T+ D+ L + +++ SL LQ E +D+ LH D P+
Sbjct: 73 GLQLATKIYPTA--NTSMPGDKYTLRAADLRQALSQSLEALQTESVDIWYLHAPDRTTPL 130
Query: 232 EELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPE 291
EE +R ++ + EG G + + E+ A C Q N + P V Q Y+ R
Sbjct: 131 EETLRAVDELYREGKFKRLGLSNFMSWEVARACDLCEQNNWVRPSVYQGIYNPLHRAIEN 190
Query: 292 LYMPEL-YHKIGV 303
+P L ++KI +
Sbjct: 191 ELVPCLRFYKIAL 203
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 58.8 bits (136), Expect = 3e-07
Identities = 49/184 (26%), Positives = 90/184 (48%), Gaps = 24/184 (13%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
SG +P +GLG + L ++ I D V AL +G D +E + E +G +L + +
Sbjct: 41 SGDTLPALGLGTYA-LDDDQIADSVRAALSSGYTHIDTAEGY--HNEEAIGEVLAEYD-- 95
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R + +T+K+ + L + +I+S +ASL RL+ +Y+D+ L+H +P
Sbjct: 96 RDDVFLTSKVL------------AKNLGYESLIQSCEASLERLETDYLDLYLIHWPNPAI 143
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPI-VEQTEYHMFCRE 288
+ E ++ M + + G V G + +S ++ +C PI V Q E+H + +
Sbjct: 144 SLRESLQAMAELHDRGLVRNVGVSNFSAYQL-----SCANHISEVPIAVNQIEFHPWF-Q 197
Query: 289 KPEL 292
+P L
Sbjct: 198 RPNL 201
>UniRef50_Q00258 Cluster: Norsolorinic acid reductase; n=17;
Dikarya|Rep: Norsolorinic acid reductase - Aspergillus
parasiticus
Length = 388
Score = 58.8 bits (136), Expect = 3e-07
Identities = 54/195 (27%), Positives = 99/195 (50%), Gaps = 11/195 (5%)
Query: 86 TYMGNHTAM-PSAVTPGLRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINL 144
T +G H + PSA G+R L + N G+ + + +++ T E+G N
Sbjct: 11 TLLGYHRILSPSA---GVRVSPLCLGTMSFGNGWKGVMGECDQATSFNMLDTFYESGGNF 67
Query: 145 FDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWS-TKFHTNN-RSDERGLSRKH 200
D++ + G+ E +G + +R R I+++TK T F +S+ +G K
Sbjct: 68 IDVANFYQG-GDTERWVGEWMAQRQ-NRDEIVLSTKYTMGYTMFGPQKIKSNFQGNHAKS 125
Query: 201 VIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
+ SVKASL +LQ +YID++ +H D +EE++R +N+++ G V+Y G + +P+ +
Sbjct: 126 LRLSVKASLQKLQTDYIDLLYVHMWDFTTSVEEVMRSLNHLVANGKVLYLGVSD-TPAWL 184
Query: 261 MDAYTNCRQFNCITP 275
+ + N +TP
Sbjct: 185 VVKCNAFARANGLTP 199
>UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1;
Mesorhizobium loti|Rep: Aryl-alcohol dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 306
Score = 58.4 bits (135), Expect = 4e-07
Identities = 40/162 (24%), Positives = 76/162 (46%), Gaps = 9/162 (5%)
Query: 107 LGKSGLRVPNIGLGLWTMLS------EESIEDVVMTALENGINLFDLSEAHCA-KGEAEL 159
L + G+ + + G W +L + + ++ TA++ G+ FD ++ + + EA
Sbjct: 9 LTRDGVSLSRLVFGAWRLLDGGVRPDADQVARLIGTAVDLGLTSFDHADIYGNYEVEAAF 68
Query: 160 GRILKKRNVRRTSIIITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
G L + +R I + +K I + NR S H+ SV SL L +Y+
Sbjct: 69 GAGLSRWRGKRDQIELVSKCDIMLPSANRPQNRLKHYDTSAAHITASVDRSLANLGTDYL 128
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSE 259
D++LLH+ DP+ +E + ++N G G + ++PS+
Sbjct: 129 DLLLLHRPDPLMDADETAAALAGLVNAGKARAVGVSNFTPSQ 170
>UniRef50_Q39G79 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 332
Score = 58.4 bits (135), Expect = 4e-07
Identities = 43/149 (28%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 141 GINLFDLSEAHCAKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSR 198
G NL D ++ + + G +E +G R R +I TK+ + H N + G
Sbjct: 22 GGNLIDTAKVY-SNGHSEKIIGDFFATRKGTRNQSVIATKL--AANLHLRNPNGG-GTGH 77
Query: 199 KHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPS 258
K +I+ +ASL RLQ +YID+ +H D P+EE +R ++ ++ G V Y G +
Sbjct: 78 KAIIDQCEASLRRLQTDYIDLYQMHIWDRHTPIEETMRALDDLVTAGKVRYIGISDTPAW 137
Query: 259 EIMDAYTNCRQFNCITPIVEQTEYHMFCR 287
++ A T I Q EY + R
Sbjct: 138 KVAQAQTTALFRGWAALISMQVEYSLLQR 166
>UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10;
Bacteria|Rep: Predicted oxidoreductase - Hahella
chejuensis (strain KCTC 2396)
Length = 345
Score = 58.4 bits (135), Expect = 4e-07
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWT---MLSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
++Y+ LGK+ L+V I LG T +E + + A+E GIN D +E + +A+
Sbjct: 1 MQYRQLGKTDLKVSAICLGTMTWGQQNTEVEAHEQLDYAVEQGINFIDTAEMYPVPPQAD 60
Query: 159 --------LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLG 210
LG LKKR+ R +I+ TK+ R R L+ H+ E++ ASL
Sbjct: 61 TQGRTESYLGSWLKKRS-DRNKLIVATKVTGPAASFGYLRGGPR-LTAAHISEAIDASLK 118
Query: 211 RLQVEYIDVVLLHKVD 226
RLQ +Y+D+ +H D
Sbjct: 119 RLQTDYVDLYQVHWPD 134
>UniRef50_A6WDF5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 310
Score = 58.4 bits (135), Expect = 4e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 107 LGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCA---KGEAELGR 161
LG S L+VPN+ LGL + + +E+I +V E GI + D ++ + + E +
Sbjct: 6 LGGSDLQVPNVVLGLMRIADMEDEAIRTLVAAGREAGITMLDHADVYGGSMHRCEERFAQ 65
Query: 162 ILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVL 221
+ + R + II TK + S ER + SV+ SL L +Y+DV+L
Sbjct: 66 AVTLSSSEREATIIQTKAGIVPDGPYFDFSHER------ITSSVEGSLKALGTDYLDVLL 119
Query: 222 LHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
LH+ D + EE+ R + + G V ++G + +P ++
Sbjct: 120 LHRPDALVEPEEVARAFDELHAAGKVRHFGVSNQTPGQM 158
>UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Eubacterium ventriosum ATCC 27560
Length = 333
Score = 58.4 bits (135), Expect = 4e-07
Identities = 41/175 (23%), Positives = 83/175 (47%), Gaps = 10/175 (5%)
Query: 123 TMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR--RTSIIITTK-- 178
T+ +++ E+++ A++ G FD +E + + L +R R I++ +K
Sbjct: 28 TVSTQKEAEELIEKAIDEGCTFFDTAEIYGTTEDPHHNEKLLGEVLRPYRNKIVLASKCG 87
Query: 179 IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVM 238
I++ T N+ + + S++ SL RL +++D+ +H++D P+EE M
Sbjct: 88 IHFDETATTVNKPLIPDGRPETIKASIEGSLMRLNTDHLDLYYIHRIDMTVPIEETAGAM 147
Query: 239 NYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELY 293
++ +G + +WG + S I A+ C +T I Q Y M R+ +L+
Sbjct: 148 KELMEQGKITHWGLSEASEEIIQRAHKVCP----VTAI--QNRYSMMYRDYEKLF 196
>UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1;
Methylophilales bacterium HTCC2181|Rep: Aldo/keto
reductase - Methylophilales bacterium HTCC2181
Length = 355
Score = 58.0 bits (134), Expect = 6e-07
Identities = 43/139 (30%), Positives = 71/139 (51%), Gaps = 13/139 (9%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMT---ALENGINLFDLSEAH--------C 152
Y+ +G S L V I LG T + + E+ A++ GIN D++E +
Sbjct: 7 YRLVGNSSLLVSPITLGTMTFGDQNTQEEAFHQLDFAIDQGINCLDVAELYPVPPKADTY 66
Query: 153 AKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
K E +G LK + +R ++++TK+ + + R L RK++IESV+ SL RL
Sbjct: 67 TKTEIIIGNWLKYQ--KREELVLSTKVAGPRRDLSWIRGGPLSLDRKNIIESVEKSLQRL 124
Query: 213 QVEYIDVVLLHKVDPVCPM 231
Q +Y+D++ LH + PM
Sbjct: 125 QTDYVDLLYLHWPERNVPM 143
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 58.0 bits (134), Expect = 6e-07
Identities = 54/194 (27%), Positives = 91/194 (46%), Gaps = 25/194 (12%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRN-- 167
+G+ +P +G G++ + E E+ V A++ G L D + ++ E +GR +K+
Sbjct: 10 NGVEMPILGYGVF-QIPPEKTEECVYEAIKVGYRLIDTAASYM--NEEGVGRAIKRAIDE 66
Query: 168 --VRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKV 225
VRR + +TTK+ W SD S K E SL +LQ+EYID+ L+H+
Sbjct: 67 GIVRREELFVTTKL-WV--------SDVGYESTKKAFEK---SLKKLQLEYIDLYLIHQ- 113
Query: 226 DPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMF 285
P + + M + +G V G + + P +MD + + I P V Q E H F
Sbjct: 114 -PFGDVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVH----HEIVPAVNQIEIHPF 168
Query: 286 CREKPELYMPELYH 299
+ + E+ Y+
Sbjct: 169 YQRQEEIEFMRNYN 182
>UniRef50_Q82LM1 Cluster: Putative aryl-alcohol dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative aryl-alcohol
dehydrogenase - Streptomyces avermitilis
Length = 342
Score = 58.0 bits (134), Expect = 6e-07
Identities = 56/204 (27%), Positives = 96/204 (47%), Gaps = 18/204 (8%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSEESI-------EDVVMTALENGINLFDLSEAHCAK 154
+RY+ LG++GLRV + LG T + + ++ E G N+ D + +
Sbjct: 1 MRYRLLGRTGLRVSELFLGAMTFGEQGGVGAPRPECARILDAYAEAGGNVIDTA-INYRG 59
Query: 155 GEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRL 212
GE+E +G +LK + R +++TK S N + G RK++ S++ SL RL
Sbjct: 60 GESETIVGELLKGQ---RDRFVLSTKYTISRDGADPNAA---GNHRKNLTLSLETSLRRL 113
Query: 213 QVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNC 272
+YIDV +H D P+EE VR ++ + G V+Y G + P+ ++ ++
Sbjct: 114 GTDYIDVYWVHIWDRNTPIEETVRALDDAVRSGKVLYVGISD-VPAWVVSRANTLAEWRG 172
Query: 273 ITPI-VEQTEYHMFCREKPELYMP 295
TP Q Y + R+ +P
Sbjct: 173 WTPFSALQVPYSLLNRDIERELLP 196
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/181 (27%), Positives = 85/181 (46%), Gaps = 20/181 (11%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G +P +GLG++ +++E +E+VV TAL+ G FD A+ E LG LK NV
Sbjct: 10 NGYPMPAVGLGVYK-IADEQMEEVVRTALDAGYRAFD--TAYFYGNEKALGSALKHSNVE 66
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLH-KVDPV 228
R + IT+K++ +D +G + IE SL L ++Y+D+ L+H +
Sbjct: 67 RDELFITSKLW----------NDYQGYDQ--TIEYFNKSLDNLGLDYLDLFLIHWPCEND 114
Query: 229 CPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCRE 288
E + + ++ EG + G + + + ITP V Q E H + +
Sbjct: 115 QLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETK----ITPQVNQIELHPYFNQ 170
Query: 289 K 289
+
Sbjct: 171 Q 171
>UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2;
Thermoplasmatales|Rep: Oxidoreductase - Picrophilus
torridus
Length = 320
Score = 58.0 bits (134), Expect = 6e-07
Identities = 51/208 (24%), Positives = 96/208 (46%), Gaps = 21/208 (10%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEE------SIEDVVMTALENGINLFDLSEAHCAKGEA 157
Y NLG + LRV + LG + S E + ++ A+++GIN D + + + GE+
Sbjct: 3 YVNLGHTDLRVSRLCLGGMSFGSSEWMVRGGDADRIIKKAIDSGINFIDTANIY-SNGES 61
Query: 158 E--LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSD-ERGLSRKHVIESVKASLGRLQV 214
E +G +K R ++I+TK SD +G +++ + + SL L+
Sbjct: 62 EIIIGNAIKD---YRDDLVISTK-------GGGKLSDFYQGFNKRVIKREIDMSLKNLKT 111
Query: 215 EYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCIT 274
+Y+DV +H + + +L++ ++ +I+ Y G + + S + + Y
Sbjct: 112 DYVDVYFMHTIFYSTDLNDLIKTLSELIDLNKTHYIGLSNFPGSLLGEFYAISDLVYNFR 171
Query: 275 PIVEQTEYHMFCREKPELYMPELY-HKI 301
P++ Q Y+ RE +P Y HKI
Sbjct: 172 PVIVQNHYNAVYREDERDVIPFCYKHKI 199
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 57.6 bits (133), Expect = 8e-07
Identities = 43/182 (23%), Positives = 83/182 (45%), Gaps = 20/182 (10%)
Query: 111 GLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRR 170
G +P +G G++ + + + V +A+ NG L D +EA+ + +G +K +V R
Sbjct: 12 GNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAY--NNQTAVGEAIKNSDVNR 69
Query: 171 TSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCP 230
I +TTK+ W + F S +++ L L +YID++LLH+
Sbjct: 70 DDIFLTTKL-WVSNFTYEKAS-----------KAIDEDLKELGTDYIDMMLLHQA--YGD 115
Query: 231 MEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKP 290
+ R + G G + + P ++M N + + + P+V Q E + + + +P
Sbjct: 116 VAGAWRALEDAQKAGKTKSIGVSNFWPDQLM----NLQLMSNVKPVVNQIEVNPWFQREP 171
Query: 291 EL 292
E+
Sbjct: 172 EV 173
>UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11;
Actinomycetales|Rep: Aldo/keto reductase - Nocardioides
sp. (strain BAA-499 / JS614)
Length = 315
Score = 57.6 bits (133), Expect = 8e-07
Identities = 49/198 (24%), Positives = 83/198 (41%), Gaps = 8/198 (4%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALENGINLFDLSEAHCAKGEAE 158
++ + +G +GL V + LG T E D ++ E G L D + + E
Sbjct: 1 MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEE 60
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
L L V R +++ TK + + E SR H++ ++ ASL RL V ++D
Sbjct: 61 LIGTLIGDVVARDDVVLATKAGITAR----RGGREYNTSRGHLLATLDASLRRLGVAHVD 116
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE 278
+ +H P+EE + ++ + G Y G + +S + A T R TP+
Sbjct: 117 LWQVHIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQAATWQRAVPGRTPLAS 176
Query: 279 -QTEYHMFCREKPELYMP 295
Q EY + R +P
Sbjct: 177 TQVEYSLLNRVAEHEVLP 194
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 57.2 bits (132), Expect = 1e-06
Identities = 48/183 (26%), Positives = 83/183 (45%), Gaps = 20/183 (10%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G+ VP +G G + + E V A++ G D ++++ E +GR + V
Sbjct: 8 NGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYM--NEEAVGRGIAASGVD 65
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R + ITTKI+ +S K V+ S SL RL ++Y+D++L+H+ P
Sbjct: 66 RKELFITTKIW------------VENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQ--PFN 111
Query: 230 PMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREK 289
+ M + G + G + +SP ++D FN +TP V Q E + F ++
Sbjct: 112 DVYGAWIAMEELQASGKIRAIGVSNFSPDRVID----LAAFNEVTPQVNQIEVNPFQQQT 167
Query: 290 PEL 292
L
Sbjct: 168 ANL 170
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 57.2 bits (132), Expect = 1e-06
Identities = 44/180 (24%), Positives = 91/180 (50%), Gaps = 21/180 (11%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
+G+ +P +GLG+W S + ++ V+ ALE G D + + E ++G+ +++ +
Sbjct: 16 NGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIY--DNEVDVGQAIRESGIP 73
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVC 229
R I ITTK++ + + SD+ +RK +++ SL RL ++++D+ L+H PV
Sbjct: 74 RKEIFITTKLW-----NADQGSDK---TRK----ALENSLDRLGIDFVDLYLIH--FPVT 119
Query: 230 PME-ELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCRE 288
+ + + + ++ G + ++ + + N + ITP V Q E+H F +
Sbjct: 120 SKRMDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQ----ITPAVNQVEFHPFLNQ 175
>UniRef50_Q5FK30 Cluster: Aldo-keto oxidoreductase; n=3;
Bacteria|Rep: Aldo-keto oxidoreductase - Lactobacillus
acidophilus
Length = 207
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 125 LSEESIEDVVMTALENGINLFDLSEAHCA---KGEAELGRILKKRNVR--RTSIIITTKI 179
+ EE + A G FD +E + G L + + R +++I TK
Sbjct: 30 MDEEEAIKTIQAAYNAGERFFDTAEIYQGVNPDGSTNYNEELVGKVLHDVRDNVVIATKF 89
Query: 180 -YWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVM 238
+ + ++ + S + + +SV+ SL RL ++ID+ H++DP EE+ +VM
Sbjct: 90 GIHNIEGKSSTQEIAVDSSPEAIRKSVEGSLKRLNTDHIDLYYQHRIDPKFSPEEVAQVM 149
Query: 239 NYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE-QTEYHMFCREKPELYMPEL 297
+I EG + +WG + +P + R+ N +T + Q Y M RE E++ L
Sbjct: 150 GELIKEGKITHWGISEATPDYL-------RRANKVTKVTAIQNRYSMMYREYEEMF--PL 200
Query: 298 YHKIGVG 304
++ VG
Sbjct: 201 LEELNVG 207
>UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1;
Psychroflexus torquis ATCC 700755|Rep: Aryl-alcohol
dehydrogenase - Psychroflexus torquis ATCC 700755
Length = 276
Score = 57.2 bits (132), Expect = 1e-06
Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 3/144 (2%)
Query: 120 GLW-TMLSEESIEDVVMTALENGINLFDLSEAHCA-KGEAELGRILKKRNVRRTSIIITT 177
G W LS + + L G+ FD ++ + EAE G + ++R SI + +
Sbjct: 4 GRWGKQLSTSQMASQIEDCLSLGVTTFDHADIYGDYTTEAEFGIAFTESKIKRESIQLIS 63
Query: 178 KIYWS-TKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVR 236
K + NNR +++I V+ S+ L +Y+D LLH+ P+ ++E+ +
Sbjct: 64 KCGLQLSNSARNNRVKHYQYDSEYIIAQVEQSISNLNCDYLDAFLLHRPSPLMDLQEIAK 123
Query: 237 VMNYVINEGWVMYWGTARWSPSEI 260
+ Y+ +G + ++G + ++ +I
Sbjct: 124 SIIYLKEQGKIKHFGVSNFTAQQI 147
>UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9;
Proteobacteria|Rep: Aldo/keto reductase - Silicibacter
sp. (strain TM1040)
Length = 296
Score = 57.2 bits (132), Expect = 1e-06
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 8/156 (5%)
Query: 110 SGLRVPNIGLGLWTM-----LSEESIEDVVMTALENGINLFDLSEAHCAKG-EAELGRIL 163
S L + G+W + S +E + LE GI FD ++ + G EA LG L
Sbjct: 8 SDLSFSRLVYGMWRIGDVKDTSPAHVEAKIAACLEQGITTFDQADIYGDYGAEAILGGAL 67
Query: 164 KKRNVRRTSIIITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVL 221
K R + I TK I + + SR H++ SV+ SL + +E ID++L
Sbjct: 68 KANPSLRDQMEIVTKCDIVAPIGRYADKSVKYYDTSRAHIMHSVETSLSEMGIEQIDLLL 127
Query: 222 LHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSP 257
+H+ DP+ E ++ ++ G V G + + P
Sbjct: 128 IHRPDPLMDHNETGAALDELVTSGKVRAVGVSNFRP 163
>UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase
family; n=4; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Arthrobacter aurescens (strain TC1)
Length = 334
Score = 57.2 bits (132), Expect = 1e-06
Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 19/206 (9%)
Query: 101 GLRYKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAEL- 159
GL+ LG G+ + + G+ EE ++ + A++ GI D ++ + A EL
Sbjct: 9 GLKVSPLGFGGMALTPVYGGIEP---EEGLQ-TLRHAVDAGITFIDTADVYGAGSNEELV 64
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
GR+LK+R R I + TK + + + RG ++ ++ +ASL RL + ID+
Sbjct: 65 GRLLKER---REEIQVATK-FGIEGNPADGYTGVRG-DAPYIRQAAEASLRRLGTDAIDL 119
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE- 278
+H+ D P+ E V M ++ EG V + G + + E+ RQ N + PI
Sbjct: 120 YYMHRRDLRVPIVETVEAMAELVREGKVRHLGLSEVTAEEL-------RQANAVHPIAAV 172
Query: 279 QTEYHMFCREKPELYMPELYHKIGVG 304
Q+E+ ++ R+ EL + ++GVG
Sbjct: 173 QSEWSIWSRD-VELNVVPAAKELGVG 197
>UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3;
Bacteroidales|Rep: Putative aldo/keto reductase -
Bacteroides fragilis
Length = 338
Score = 56.8 bits (131), Expect = 1e-06
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 11/165 (6%)
Query: 132 DVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRS 191
+ + A + G FD +EA+ G+ + + V + ++ +TKFH S
Sbjct: 36 EAIRGAYDYGCTHFDTAEAY---GKEQFYAGHNEELVGKAIEPFRKEVVLATKFHIGELS 92
Query: 192 --DERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMY 249
DE L R+ V ++ S+ RL+ +YID+ LH+++ +E++ VM ++ EG +
Sbjct: 93 KPDETSLYRE-VRRHLEDSMSRLRTDYIDLYYLHRINETVRLEDVATVMGRLVKEGLIRG 151
Query: 250 WGTARWSPSEIMDAY--TNCRQFNCITPIVE---QTEYHMFCREK 289
WG ++ S +I A+ T I +VE +TE C EK
Sbjct: 152 WGLSQVSADQIRAAHKITPLSAVQNIYSMVERDCETEIFPVCLEK 196
>UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:
Aldo/keto reductase - Lactobacillus reuteri 100-23
Length = 327
Score = 56.8 bits (131), Expect = 1e-06
Identities = 45/147 (30%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
Query: 118 GLGLWTMLSEESIEDVVMTALENGINLFDLSEAH-CAKGEAELGRILKKRNVRRTSIIIT 176
G L+ L +++ D+V TAL+NGINL D + + E +G+ ++ + R III
Sbjct: 26 GYNLFPGLDDQAGIDLVKTALDNGINLLDTAYVYGLGHSEELIGQAIQDYD--RHKIIIA 83
Query: 177 TKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVR 236
TK + F T + + V SL RLQ +YID+ LH D P E V
Sbjct: 84 TK--GAHDFSTGKEVINN--DPDFITKQVNDSLKRLQTDYIDIYYLHFPDHDTPKAEAVG 139
Query: 237 VMNYVINEGWVMYWGTARWSPSEIMDA 263
+ + EG + G + +S ++I +A
Sbjct: 140 ALQKLREEGKIRAIGISNFSLAQIKEA 166
>UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: Ydhf chain A - Stigmatella aurantiaca
DW4/3-1
Length = 305
Score = 56.4 bits (130), Expect = 2e-06
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 9/162 (5%)
Query: 107 LGKSGLRVPNIGLGLWTMLSEESIEDV------VMTALENGINLFDLSEAHCAKGEAEL- 159
+ G V + G+W M + D V L+ GI FD ++ + EL
Sbjct: 9 MAPQGPEVSRLVYGVWRMQEDAQGTDPQRVLGKVQACLDLGITTFDHADIYGGYRCEELF 68
Query: 160 GRILKKRNVRRTSIIITTK--IYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
G L+ R + + TK I + N SR+H+I SV+ SL L +YI
Sbjct: 69 GAALRTNPGLRQRLELVTKCGIMLTHPARPQNWIKHYDYSRQHLIGSVEQSLRNLATDYI 128
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSE 259
DV+LLH+ P+ E + ++ +G V + G + ++P++
Sbjct: 129 DVLLLHRPSPLLDPAEAAEALRLLVEQGKVRHVGVSNFTPAQ 170
>UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2;
Planctomycetaceae|Rep: Aldo/keto reductase -
Planctomyces maris DSM 8797
Length = 317
Score = 56.4 bits (130), Expect = 2e-06
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 105 KNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAHCAKGEA 157
+N+G + +++ I +G W + ++E++ + A E+GIN FD + + +GE+
Sbjct: 5 RNIGNTDIQITPIAMGCWPISGVTSVDVTEQASLATLNAAFESGINFFDTAYCYGYEGES 64
Query: 158 ELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYI 217
E I + RR I+I TK H R S + + SL RL + +
Sbjct: 65 ER-LIAQALGDRRDQIVIATK----GGIHWQGTKQVRDASPARIRQECDESLQRLNTDRV 119
Query: 218 DVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNC 267
++ LH DP P+ E ++ G ++ G + ++ ++ + C
Sbjct: 120 ELYYLHGPDPEIPVSESAGAFQELLASGKILSVGVSNFTLEQLQEFARVC 169
Score = 47.6 bits (108), Expect = 8e-04
Identities = 23/60 (38%), Positives = 33/60 (55%)
Query: 410 GEEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQ 469
GEE D L L LAN +N +++Q+ V W ++ + C L GA EQ +EN AL+
Sbjct: 235 GEEWEKNQDFLDVLRTLANEMNRTVAQIVVRWTIQQPGITCALCGAKRPEQIRENAEALE 294
>UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus
solfataricus|Rep: Oxidoreductase - Sulfolobus
solfataricus
Length = 304
Score = 56.4 bits (130), Expect = 2e-06
Identities = 61/246 (24%), Positives = 107/246 (43%), Gaps = 32/246 (13%)
Query: 105 KNLGKSGLRVPNIGLGLW-----TMLSEESIEDVVMTALENGINLFDLSEAHC-AKGEAE 158
K LG + ++ + LG W +++ E + + A+E GIN D +E++ E
Sbjct: 4 KPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLSETI 63
Query: 159 LGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYID 218
+GR + K +R + I TK+ + R D+ V+++ + SL RL YID
Sbjct: 64 IGRAISK--FKREDLFIITKVSID-----HLRYDD-------VLKASEGSLKRLNTSYID 109
Query: 219 VVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI---------MDAYTNCRQ 269
+ L+H + P+ E + M + NEG + Y G + +S + D N
Sbjct: 110 LYLVHWPNHYVPIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSKTDVAANELH 169
Query: 270 FNCITPIVEQTEYHMFCREKPELYMPELYHKIGVGKIYILFFIQLNYRSLVPCNSIWVKL 329
+N + VE+ RE L Y +G+G + ++ YR V ++K
Sbjct: 170 YNVLFRDVEKEVLPYMLRENIPLL---AYDALGLGYLIGRKEVRNEYRWYVLARETYIKN 226
Query: 330 LKPLAD 335
L+PL +
Sbjct: 227 LEPLIE 232
>UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG18547-PA - Nasonia vitripennis
Length = 346
Score = 56.0 bits (129), Expect = 2e-06
Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 13/132 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM------LSEESIEDVVMTALENGINLFDLSEAHC-AK 154
+ Y+ LGK+GL V + LG T+ E+ + + A++ GIN D + + K
Sbjct: 22 MEYRTLGKTGLMVSKLSLGGGTLGCHYAAFDEDEAIETIRKAIKKGINYIDTAYWYGQGK 81
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E +G+ LK + R + I TK+ + N D S + V +SVK SL RLQ+
Sbjct: 82 SELIIGKALK--GIPRQAYYIGTKV-GRYELDFANMFD---FSMERVRQSVKQSLERLQL 135
Query: 215 EYIDVVLLHKVD 226
+Y+DV+ +H ++
Sbjct: 136 DYVDVIQIHDIE 147
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 56.0 bits (129), Expect = 2e-06
Identities = 45/184 (24%), Positives = 85/184 (46%), Gaps = 25/184 (13%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILK---KR 166
+G+++P +GLG +++ + + + A+E G LFD ++ + EAELG + K
Sbjct: 8 NGVKMPILGLGTYSLTGKAG-QKAMSEAIEVGYRLFDSAQMY--NNEAELGAAINAAVKG 64
Query: 167 NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVD 226
++R I TK+ S L++K S++ SL L ++YID +L+H
Sbjct: 65 GIKREEFFIQTKLL---------ESSSEDLAKK----SIEKSLKTLGLDYIDSLLIHM-- 109
Query: 227 PVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFC 286
P + + R M +G + G + + + +C + P + Q E H+
Sbjct: 110 PYSQSKAMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCE----VIPAINQCETHLLL 165
Query: 287 REKP 290
++KP
Sbjct: 166 QQKP 169
>UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2;
Clostridiales|Rep: Predicted oxidoreductases -
Pelotomaculum thermopropionicum SI
Length = 335
Score = 56.0 bits (129), Expect = 2e-06
Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 20/126 (15%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM--LSEESIEDVVMTALENGINLFDLSEAHCAKGEAEL 159
+RY+ LG++GL+V IG G + +S E V+ ALE GIN FD + A+ E +L
Sbjct: 1 MRYRRLGRTGLQVAEIGFGGIPIQRISGEEAAAVINRALELGINFFDTARAY-TDSEEKL 59
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G +L+K RR +II TK +R+ + ++ SL + +EYID+
Sbjct: 60 GAVLRK---RRGDVIIATK--------------SMARTREKMAADIRRSLEVMGLEYIDL 102
Query: 220 VLLHKV 225
+H V
Sbjct: 103 YQMHNV 108
>UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp.
PR1|Rep: Oxidoreductase - Algoriphagus sp. PR1
Length = 296
Score = 56.0 bits (129), Expect = 2e-06
Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 7/158 (4%)
Query: 105 KNLGKSGLRVPNIGLGLWTMLSE-ESIEDVVMTALENGINLFDLSEAHCAKGEAE-LGRI 162
+ L ++ L++ + LG ++ E +S + ++ A+E GI+L D ++ + E LG+
Sbjct: 4 RELSETKLQISELSLGCMSLPEEYDSSKKILDAAIEGGISLLDTADLYQQGWNEEMLGKA 63
Query: 163 LKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
LK R R +++ TK+ + + + +++++ +V+ SL RLQ +YID+ L
Sbjct: 64 LKGR---RNQLVLATKV--GNQLRPDGSGWDWNPKKEYILGAVEQSLKRLQTDYIDLYQL 118
Query: 223 HKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEI 260
H P +E + + +G + +G + P+ I
Sbjct: 119 HGGTIEDPWDETLEAFELLKTQGKIRAFGISSIRPNVI 156
>UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 324
Score = 56.0 bits (129), Expect = 2e-06
Identities = 44/178 (24%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 126 SEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTKF 185
++ES E V+ L G+ D + + EA +G++ K RT +I TK+ F
Sbjct: 19 TQESREKVLDLLLSYGVKNIDTARLYGGSEEA-IGKLAK-----RTEFVIDTKLVGG--F 70
Query: 186 HTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEG 245
N + + VI + SL R+ ++ DV+ +H D P EE + +N V +G
Sbjct: 71 SPGN------VHKDQVIADAQHSLDRVGIKQFDVLYIHAPDETIPFEETLEGVNEVYKKG 124
Query: 246 WVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMPELYHKIGV 303
+G + ++ +++ Y ++ + P + Q Y R L P L K+G+
Sbjct: 125 IFRRFGLSNFNSAQVQQVYDISKKNGWVLPTMYQGNYSPIARHLETLLFP-LLKKLGI 181
>UniRef50_Q0CZ87 Cluster: Norsolorinic acid reductase; n=1;
Aspergillus terreus NIH2624|Rep: Norsolorinic acid
reductase - Aspergillus terreus (strain NIH 2624)
Length = 387
Score = 56.0 bits (129), Expect = 2e-06
Identities = 45/169 (26%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 103 RYKNLGKS-GLRVPNIGLGL------WTM--------LSEESIEDVVMTALENGINLFDL 147
RY+ L S GLRV +GLG W + + ++ +++ E G N D
Sbjct: 15 RYRLLAPSAGLRVSPLGLGSMAFGEKWLLDRSAVLGKCEKPTVFEILDFFYEQGGNFIDT 74
Query: 148 SEAHC-AKGEAELGRILKKRNVRRTSIIIT--TKIYWSTKFHTNNRSDERGLSRKHVIES 204
+ + + EA +G + R+ R II T + Y + R++ G + K +++S
Sbjct: 75 ANNYQEGESEAWIGEWMVARSNREELIIATKYSSAYTQDGSESTIRANRGGNATKSMVQS 134
Query: 205 VKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTA 253
++ SL RLQ Y+D++ +H D + EL++ +N+++ G V+Y G +
Sbjct: 135 LEKSLQRLQTRYVDILYVHYWDFTTSIPELMQSLNHLVASGKVLYLGVS 183
Score = 37.9 bits (84), Expect = 0.66
Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 411 EEPRTYGDKLRDLANLANSLNCSMSQLAVAWCLKNESVNCLLLGATSVEQFKENIHALQV 470
+E R G+K+R NLA + + LA+A+ + ++G +VEQ K+N+ AL++
Sbjct: 264 KEMRKIGEKIR---NLAEQMKTHPTALALAYIMSKAPYTFPIVGVRTVEQLKQNLQALEL 320
Query: 471 YI 472
I
Sbjct: 321 QI 322
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 56.0 bits (129), Expect = 2e-06
Identities = 41/113 (36%), Positives = 56/113 (49%), Gaps = 15/113 (13%)
Query: 110 SGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVR 169
SG +P +GLG W E +E+ V TAL G D A C E E+G KK V
Sbjct: 11 SGYDMPAVGLGTWLSKPHE-VENAVETALRLGYRHIDA--AACYLNENEVGNGWKKSGVP 67
Query: 170 RTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLL 222
R I IT+K+ W+T H + HV E+V +L LQ +Y+D+ L+
Sbjct: 68 RDQIFITSKL-WNTHHHPD-----------HVEEAVNKTLKDLQTDYLDLYLV 108
>UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagus
degradans 2-40|Rep: Aldo/keto reductase - Saccharophagus
degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length = 332
Score = 55.6 bits (128), Expect = 3e-06
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 10/159 (6%)
Query: 114 VPNIGLGLWTMLSEESIEDVV--MTALENGINL----FDLSEAH-CAKGEAELGRILKKR 166
VP +GLG M D + L NL FD ++ + E +G+ + +
Sbjct: 10 VPAVGLGCMGMSEFYGAADEATSLQTLNEAFNLGYRHFDTADMYGFGHNETLVGKFINQE 69
Query: 167 NVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESV-KASLGRLQVEYIDVVLLHKV 225
N+ R + I+TK N++ + S + I + +ASL RL EYID+ LH++
Sbjct: 70 NINREELFISTK--GGIVRDVNDKYNVSVNSTEQYIRAACEASLKRLNTEYIDLYYLHRL 127
Query: 226 DPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAY 264
DP +EE + + ++ EG + G S ++ A+
Sbjct: 128 DPAIELEESIGTLKALVKEGKIKNIGLCEVSEDQLAKAH 166
>UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,
putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B, putative - Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain
OCh 114)) (Roseobacter denitrificans)
Length = 272
Score = 55.6 bits (128), Expect = 3e-06
Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 20/160 (12%)
Query: 125 LSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGRILKKRNVRRTSIIITTKIYWSTK 184
L + D ++TA E G FD ++ + + EAE G LK+ + R ++ +TTK+
Sbjct: 18 LKGTACRDAILTAAEVGYRAFDTAQMY--RNEAETGAALKETGIPRDTLCVTTKV----- 70
Query: 185 FHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINE 244
N+ DE + SV+ASL LQ++Y+DV+LLH +E + ++
Sbjct: 71 --ENDNYDE-----SKFLASVEASLKALQLDYVDVLLLHWPPADFQIEGSLTLLEQAHKR 123
Query: 245 GWVMYWGTARWSPSEIMDAYTNCRQFNCITPIV-EQTEYH 283
G G + ++ + DA T + TP+V Q E+H
Sbjct: 124 GMARNIGVSNYTVQMMRDA-TRIIE----TPLVTNQIEFH 158
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 55.6 bits (128), Expect = 3e-06
Identities = 46/193 (23%), Positives = 97/193 (50%), Gaps = 25/193 (12%)
Query: 104 YKNLGKSGLRVPNIGLGLWTMLSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGR-I 162
YK L SG+ +P +G G++ + + + + V+ A++ G L D + ++ E E+G I
Sbjct: 3 YKTLA-SGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASY--GNEREVGEAI 59
Query: 163 LKKRN---VRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
L+ N V+R + +T+K++ + +S + ++++SL RL ++Y+D+
Sbjct: 60 LEAINQGIVKREELFVTSKMW------------VQDVSAQQATAAIQSSLQRLNLDYLDL 107
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQ 279
L+H+ P + R M G + G + + +++ TN +F+ I P++ Q
Sbjct: 108 YLIHQ--PYNDVFGAWRAMESAYRSGQLKAIGVSNFDIAQL----TNLAEFSDIKPMLNQ 161
Query: 280 TEYHMFCREKPEL 292
E + F + K ++
Sbjct: 162 IEVNPFQQNKKDI 174
>UniRef50_A5FGY2 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Flavobacterium johnsoniae UW101
Length = 328
Score = 55.6 bits (128), Expect = 3e-06
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 19/198 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM-------LSEESIEDVVMTALENGINLFDLSEAH-CA 153
+ Y+ LGK+ + I LG W + ++++ ++++ TA++NG+N D ++ +
Sbjct: 1 MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENG 60
Query: 154 KGEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQ 213
E +GR+++ R+ R I + TK H N G K + + V+ SL R
Sbjct: 61 LSETAVGRVVRSRSER---IYVATKCGRQINPHVN-----EGYQPKVLQKFVEDSLKRTG 112
Query: 214 VEYIDVVLLH-KVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDA--YTNCRQF 270
+E +D++ LH V E+ + + + ++G + G + E + A Y+N
Sbjct: 113 LETLDLIQLHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEALKAIEYSNVTTV 172
Query: 271 NCITPIVEQTEYHMFCRE 288
I + Q +F E
Sbjct: 173 QIIFNLFRQRPSQLFFSE 190
>UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 247
Score = 55.6 bits (128), Expect = 3e-06
Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 8/137 (5%)
Query: 102 LRYKNLGKSGLRVPNIGLG-LWTMLSEESIEDVVMTALENGINLFDLSEAHC-AKGEAEL 159
+RY+ LGK+GL+V + G ++ EE VV AL++GIN D + + K E L
Sbjct: 12 MRYRLLGKTGLQVSVLSFGSVFRETREEESIQVVHHALKSGINYIDTAPWYGHGKSEMVL 71
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G+ L+ + R + I++TK+ + D S + V++SV SL RL ++Y+D+
Sbjct: 72 GKALQ--GIPREAYILSTKVGRYLP-EVDKMFD---FSAERVLKSVDESLARLGLDYVDI 125
Query: 220 VLLHKVDPVCPMEELVR 236
+ +H ++ ++ +V+
Sbjct: 126 IQVHDMEFAQSLDIIVK 142
>UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagus
degradans 2-40|Rep: Aldo/keto reductase - Saccharophagus
degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length = 301
Score = 55.2 bits (127), Expect = 4e-06
Identities = 47/189 (24%), Positives = 83/189 (43%), Gaps = 16/189 (8%)
Query: 106 NLGKSGLRVPNIGLGLWTM----LSEESIEDVVMTALENGINLFDLSEAHCAKGEAELGR 161
++ + G + G W + ++++ + + LE GI D A + E GR
Sbjct: 7 SMAEDGFEFSRLIAGFWRLKDWGMNDQEVLAFIEQCLELGITTMD--HAMVYRSEEPFGR 64
Query: 162 ILKKRNVRRTSIIITTKI------YWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVE 215
L + R + I TK + N D S KH++ SV+ SL L+ +
Sbjct: 65 ALALKPELRDRMEIVTKCGIRPVGFGKLGAKAVNHYDS---SPKHIVASVEQSLRDLKTQ 121
Query: 216 YIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITP 275
YID++L+H+ D + MEE+ V + + + G V +G + ++ + C IT
Sbjct: 122 YIDLLLIHRPDYLMEMEEIAEVFDRLESSGKVRNFGVSNFTTHQFAALQQAC-DHKLITN 180
Query: 276 IVEQTEYHM 284
VE + Y+M
Sbjct: 181 QVEFSPYNM 189
>UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2;
Trichocomaceae|Rep: Aldo/keto reductase - Aspergillus
clavatus
Length = 332
Score = 55.2 bits (127), Expect = 4e-06
Identities = 56/195 (28%), Positives = 97/195 (49%), Gaps = 26/195 (13%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM---LSEESIEDVVMTALEN----GINLFDLSEAHCAK 154
L ++LG+ G +VP IG GL ++ D + LE+ G+ +D+++ + A
Sbjct: 3 LPLRSLGRDGPQVPAIGFGLGSLGGFYGPVGTLDEKVALLEHAHASGLRFWDMADVY-AD 61
Query: 155 GEAELGRILKKRNVRRTSIIITTK---IYWSTKFHTNNRSDERGLSRKHVIESVKASLGR 211
E +G +K R+ +R I + TK + T H RSD +++ E+ + SL R
Sbjct: 62 SEDVVGEWIK-RSGKRGDIFLATKGALLRQPTGGHAF-RSDP-----EYIKEACEKSLQR 114
Query: 212 LQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFN 271
L V+ ID+ H+VD + P+E+ + M + N+G + Y G SE+ + R+ +
Sbjct: 115 LGVDTIDLYYCHRVDGMTPIEKTIEAMVELKNQGKIRYLGL-----SEV--SVATLRRAH 167
Query: 272 CITPIVE-QTEYHMF 285
+ PI Q EY +F
Sbjct: 168 AVHPIAALQMEYSLF 182
>UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep:
Aldo/keto reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 286
Score = 54.8 bits (126), Expect = 5e-06
Identities = 48/194 (24%), Positives = 95/194 (48%), Gaps = 18/194 (9%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLSE-ESIEDVVMTALENGINLFDLSEAHCAK-GEAEL 159
L LG +R+ G G+W + E ++V+ A+E G+N D ++++ + E +
Sbjct: 17 LEINRLGFGAMRIT--GNGIWGEPPDREKAKEVLRKAVELGVNFIDTADSYGPQVSERLI 74
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G L + +++ TK + N+ E G +++++ V+ SL L+VE +D+
Sbjct: 75 GEALAPY---KKGVVVATKAGFLRT--GPNKWHELG-KPEYLVQQVELSLRNLKVERLDL 128
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVE- 278
LH++DP P+E+ + + + +G + + G + S EI Q + PIV
Sbjct: 129 WQLHRIDPKFPVEDSLSAIKKLQEQGKIRHVGLSEVSVKEI-------EQARKVMPIVSV 181
Query: 279 QTEYHMFCREKPEL 292
Q EY++ R+ ++
Sbjct: 182 QNEYNLANRKSEDV 195
>UniRef50_A3XNV0 Cluster: Aldo/keto reductase family protein; n=1;
Leeuwenhoekiella blandensis MED217|Rep: Aldo/keto
reductase family protein - Leeuwenhoekiella blandensis
MED217
Length = 314
Score = 54.8 bits (126), Expect = 5e-06
Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 15/159 (9%)
Query: 138 LENGINLFDLSEAHC------AKGEAE--LGRILKKRNVRRTSIIITTKIYWSTKFHTNN 189
LE G+N+ D + + + GE+E +G+ L +R R +II TK+ +NN
Sbjct: 39 LERGLNVIDTANVYSYWGEGNSGGESETVIGQWLHERK-NRDQVIIATKVGSPIGDESNN 97
Query: 190 RSDERGLSRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMY 249
LS ++ E + SL RLQ +Y+D+ HK D E + ++INEG V
Sbjct: 98 ------LSAAYIKEQIDLSLKRLQTDYVDIYFSHKYDESVTQRETLAAYKHLINEGKVRE 151
Query: 250 WGTARWSPSEIMDAYTNCRQFNCITPIVEQTEYHMFCRE 288
G + + + + DA + + Q +Y++ RE
Sbjct: 152 IGASNFPLAVLRDAIELSKAEDLPMYNYVQPQYNLMERE 190
>UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila
pseudoobscura|Rep: GA14985-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 364
Score = 54.8 bits (126), Expect = 5e-06
Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTMLS------EESIEDVVMTALENGINLFDLSEAHC-AK 154
+ Y+ LGK+GL V I G + + EE I+ V AL++GIN D + + +
Sbjct: 22 MEYRKLGKTGLEVSKISFGGGALCANYGFDLEEGIK-TVQDALKSGINYIDTAPWYGQGR 80
Query: 155 GEAELGRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQV 214
E LG+ LK +V R S I TK+ + N D S K ESV+ SL L +
Sbjct: 81 SEEVLGQALK--DVPRESYYIATKVA-RYELDPNKMFD---FSAKKTRESVEKSLKLLGL 134
Query: 215 EYIDVVLLHKVDPV----CPMEELVRVMNYVINEGWVMYWGTARWSPSEIMD 262
+Y+DV+ +H ++ + E + + ++ EG Y G + + S + +
Sbjct: 135 QYVDVIQIHDIEFAENLDIVLHETLPTLEALVKEGKAKYIGVSAYPISVLKE 186
>UniRef50_A2QN65 Cluster: Function: A. parasiticus norA has
norsolorinic acid reductase; n=1; Aspergillus niger|Rep:
Function: A. parasiticus norA has norsolorinic acid
reductase - Aspergillus niger
Length = 387
Score = 54.8 bits (126), Expect = 5e-06
Identities = 44/159 (27%), Positives = 76/159 (47%), Gaps = 4/159 (2%)
Query: 141 GINLFDLSEAHCA-KGEAELGRILKKRN-VRRTSIIITTKIYWST--KFHTNNRSDERGL 196
G N D + A+ A + E +G + R+ RR+ ++I TK S + + S+ G
Sbjct: 67 GGNFIDTANAYQAGQSEEWIGEWMATRSPTRRSEMVIATKYTLSPIPQGSSIQESNFGGN 126
Query: 197 SRKHVIESVKASLGRLQVEYIDVVLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWS 256
K + S++ SL RL+ +YID+ +H D +EEL++ +N+++ +G V+Y G +
Sbjct: 127 GTKSMRVSIEESLRRLRTDYIDIYYVHAWDYSTNIEELMQSLNHLVAQGKVLYLGISDAP 186
Query: 257 PSEIMDAYTNCRQFNCITPIVEQTEYHMFCREKPELYMP 295
+ A T R V Q Y CR+ +P
Sbjct: 187 AWVVSKANTYARVHGLRGFSVYQGRYGATCRDLEREIIP 225
>UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;
n=10; Pezizomycotina|Rep: Aldo-keto reductase (AKR13),
puatative - Aspergillus clavatus
Length = 348
Score = 54.8 bits (126), Expect = 5e-06
Identities = 54/209 (25%), Positives = 97/209 (46%), Gaps = 19/209 (9%)
Query: 107 LGKSGLRVPNIGLGLWTMLS-----EESIEDVVM--TALENGINLFDLSEAHCAKGEAEL 159
LG +G +V +G GL + S + E + + A E G +D ++ + E L
Sbjct: 9 LGANGPQVSRLGFGLMGLSSFYGPAKPDSERLALLDAAYELGETFWDSADIY-GDSEELL 67
Query: 160 GRILKKRNVRRTSIIITTKIYWSTKFHTNNRSDERGLSRKHVIESVKASLGRLQVEYIDV 219
G+ K +R + + TK ++ + +T+ G S ++V + + SL RL +E ID+
Sbjct: 68 GKWFKANPSKRQDVFLVTK--FANRQNTDGDWYVDG-SPEYVRAACERSLSRLGIETIDL 124
Query: 220 VLLHKVDPVCPMEELVRVMNYVINEGWVMYWGTARWSPSEIMDAYTNCRQFNCITPIVEQ 279
H++D P+E+ + M + NEG + Y G + S D+ + + IT + Q
Sbjct: 125 YYCHRIDRKTPIEKTIEAMVQLKNEGKIKYLGLSECS----ADSLRRAHKVHPITAV--Q 178
Query: 280 TEYHMFCR--EKPELYMPELYHKIGVGKI 306
EY F E P+ + E ++GV +
Sbjct: 179 MEYSPFALDIESPQYKVLETARELGVAVV 207
>UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: Aldo/keto reductase -
Candidatus Nitrosopumilus maritimus SCM1
Length = 332
Score = 54.8 bits (126), Expect = 5e-06
Identities = 40/134 (29%), Positives = 72/134 (53%), Gaps = 16/134 (11%)
Query: 102 LRYKNLGKSGLRVPNIGLGLWTM--------LSEESIEDVVMTALENGINLFDLSEAHCA 153
++YK LGKSG+ V IG G W++ + E+ + ++ A + GIN F+ ++ +
Sbjct: 1 MKYKKLGKSGIEVSEIGFGAWSIALDWWGKKVEEDEAKRMLKKAYDLGINYFETADMY-G 59
Query: 154 KGEAE--LGRILKKRNVRRTSIIITTKI-Y-WSTKFHTNNRSDERGLSRKHVIESVKASL 209
KG++E +G + K R ++I+TK Y +S + + S ++ ++V A L
Sbjct: 60 KGKSERLIGEVFKG---MRDEVVISTKYGYDFSDVEQIGHAELPQDYSPEYTRKAVDACL 116
Query: 210 GRLQVEYIDVVLLH 223
RLQ +Y+D + LH
Sbjct: 117 ERLQTDYLDSLGLH 130
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 581,200,765
Number of Sequences: 1657284
Number of extensions: 23852655
Number of successful extensions: 53971
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 309
Number of HSP's successfully gapped in prelim test: 373
Number of HSP's that attempted gapping in prelim test: 52898
Number of HSP's gapped (non-prelim): 975
length of query: 529
length of database: 575,637,011
effective HSP length: 104
effective length of query: 425
effective length of database: 403,279,475
effective search space: 171393776875
effective search space used: 171393776875
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)
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