Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000684-TA|BGIBMGA000684-PA|IPR001611|Leucine-rich
repeat, IPR003591|Leucine-rich repeat, typical subtype
(563 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 122 3e-27
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 122 3e-27
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 122 3e-27
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 121 6e-27
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 119 3e-26
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 119 3e-26
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 119 3e-26
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 119 3e-26
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 119 3e-26
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 117 1e-25
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 117 1e-25
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 117 1e-25
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 117 1e-25
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 109 3e-23
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 109 3e-23
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 108 4e-23
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 108 4e-23
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 108 4e-23
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 108 4e-23
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 107 8e-23
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 107 1e-22
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 107 1e-22
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 107 1e-22
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 107 1e-22
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 107 1e-22
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 107 1e-22
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 107 1e-22
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 106 2e-22
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 106 2e-22
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 105 3e-22
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 103 2e-21
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 103 2e-21
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 102 3e-21
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 102 3e-21
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 102 3e-21
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 99 5e-20
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 99 5e-20
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 99 5e-20
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 99 5e-20
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 93 2e-18
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 93 2e-18
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 93 2e-18
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 93 2e-18
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 93 2e-18
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 93 2e-18
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 92 4e-18
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 92 4e-18
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 91 7e-18
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 91 7e-18
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 91 1e-17
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 91 1e-17
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 90 2e-17
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 90 2e-17
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 90 2e-17
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 90 2e-17
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 90 2e-17
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 90 2e-17
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 89 4e-17
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 89 4e-17
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 89 4e-17
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 88 7e-17
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 88 7e-17
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 88 7e-17
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 88 7e-17
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 88 9e-17
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 88 9e-17
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 88 9e-17
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 88 9e-17
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 87 2e-16
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 87 2e-16
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 87 2e-16
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 87 2e-16
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 87 2e-16
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 87 2e-16
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 87 2e-16
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 87 2e-16
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 87 2e-16
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 87 2e-16
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 87 2e-16
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 87 2e-16
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 86 3e-16
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 86 4e-16
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 86 4e-16
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 86 4e-16
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 86 4e-16
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 86 4e-16
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 86 4e-16
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 85 5e-16
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 85 5e-16
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 85 5e-16
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 85 5e-16
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 85 5e-16
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 85 5e-16
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 85 5e-16
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 85 5e-16
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 84 1e-15
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 83 2e-15
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 83 2e-15
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 83 3e-15
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 83 3e-15
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 83 3e-15
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 83 3e-15
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 83 3e-15
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 83 3e-15
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 83 3e-15
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 80 2e-14
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 80 2e-14
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 80 2e-14
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 80 2e-14
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 79 3e-14
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 79 3e-14
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 77 1e-13
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 77 1e-13
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 77 1e-13
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 77 1e-13
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 77 1e-13
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 77 2e-13
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 77 2e-13
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 77 2e-13
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 77 2e-13
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 77 2e-13
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 77 2e-13
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 77 2e-13
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 77 2e-13
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 76 3e-13
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 76 3e-13
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 76 3e-13
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 76 3e-13
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 76 4e-13
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 76 4e-13
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 76 4e-13
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 76 4e-13
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 76 4e-13
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 76 4e-13
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 75 5e-13
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 75 5e-13
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 75 5e-13
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 75 5e-13
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 75 5e-13
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 75 5e-13
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 75 5e-13
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 75 5e-13
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 74 1e-12
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 74 1e-12
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 74 2e-12
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 74 2e-12
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 74 2e-12
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 73 2e-12
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 73 2e-12
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 73 2e-12
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 73 2e-12
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 73 3e-12
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 73 3e-12
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 73 3e-12
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 73 3e-12
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 73 3e-12
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 73 3e-12
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 73 3e-12
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 73 3e-12
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 73 3e-12
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 73 3e-12
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 73 3e-12
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 73 3e-12
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 72 5e-12
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 72 5e-12
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 72 5e-12
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 72 5e-12
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 72 5e-12
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 72 5e-12
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 72 5e-12
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 72 6e-12
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 72 6e-12
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 72 6e-12
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 72 6e-12
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 72 6e-12
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 71 1e-11
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 71 1e-11
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 71 1e-11
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 71 1e-11
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 71 1e-11
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 71 1e-11
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 71 1e-11
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 71 1e-11
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 71 1e-11
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 71 1e-11
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 71 1e-11
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 71 1e-11
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 71 1e-11
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 71 1e-11
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 71 1e-11
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 71 1e-11
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 70 2e-11
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 70 2e-11
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 70 2e-11
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 70 2e-11
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 70 3e-11
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 70 3e-11
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 70 3e-11
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 69 3e-11
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 69 4e-11
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 69 4e-11
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 69 4e-11
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 69 4e-11
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 69 4e-11
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 69 6e-11
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 69 6e-11
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 69 6e-11
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 69 6e-11
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 69 6e-11
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 69 6e-11
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 69 6e-11
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 69 6e-11
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 69 6e-11
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 69 6e-11
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 69 6e-11
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 69 6e-11
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 68 1e-10
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 68 1e-10
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 68 1e-10
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 68 1e-10
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 68 1e-10
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 67 1e-10
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 67 1e-10
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 67 1e-10
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 67 1e-10
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 67 2e-10
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 67 2e-10
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 67 2e-10
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 66 2e-10
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 66 2e-10
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 66 2e-10
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 66 2e-10
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 66 2e-10
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 66 3e-10
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 66 3e-10
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 66 3e-10
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 66 3e-10
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 66 3e-10
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 66 3e-10
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 66 3e-10
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 66 3e-10
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 66 3e-10
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 66 3e-10
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 66 4e-10
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 65 5e-10
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 65 5e-10
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 65 5e-10
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 65 5e-10
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 65 5e-10
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 65 5e-10
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 65 5e-10
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 65 5e-10
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 65 5e-10
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 65 5e-10
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 65 5e-10
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 65 5e-10
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 65 5e-10
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 65 5e-10
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 65 7e-10
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 65 7e-10
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 64 9e-10
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 64 9e-10
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 64 9e-10
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 64 9e-10
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 64 9e-10
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 64 9e-10
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 64 9e-10
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 64 9e-10
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 64 9e-10
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 64 9e-10
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 64 9e-10
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 64 1e-09
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 64 1e-09
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 64 1e-09
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 64 1e-09
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 64 1e-09
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 64 1e-09
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 64 2e-09
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 64 2e-09
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 64 2e-09
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 64 2e-09
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 64 2e-09
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 64 2e-09
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 64 2e-09
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 63 2e-09
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 63 2e-09
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 63 2e-09
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 63 2e-09
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 63 2e-09
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 63 2e-09
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 63 2e-09
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 63 3e-09
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 63 3e-09
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 62 4e-09
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 62 4e-09
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 62 4e-09
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 62 4e-09
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 62 4e-09
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 62 4e-09
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 62 4e-09
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 62 4e-09
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 62 4e-09
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 62 4e-09
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 62 4e-09
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 62 5e-09
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 5e-09
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 5e-09
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 5e-09
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 5e-09
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 62 5e-09
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 62 5e-09
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 5e-09
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 62 5e-09
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 62 5e-09
X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein. 61 9e-09
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 61 9e-09
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 61 9e-09
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 61 9e-09
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 61 1e-08
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 61 1e-08
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 61 1e-08
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 61 1e-08
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 61 1e-08
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 61 1e-08
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 61 1e-08
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 61 1e-08
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 61 1e-08
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 61 1e-08
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 61 1e-08
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 61 1e-08
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 61 1e-08
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 61 1e-08
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 61 1e-08
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 61 1e-08
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 60 2e-08
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 60 2e-08
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 60 2e-08
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 60 2e-08
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 60 2e-08
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 60 2e-08
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 60 2e-08
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 60 2e-08
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 60 2e-08
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 60 2e-08
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 60 2e-08
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 60 2e-08
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 60 2e-08
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 60 2e-08
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 60 2e-08
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 60 2e-08
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 60 2e-08
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 60 2e-08
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 60 2e-08
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 60 3e-08
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 60 3e-08
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 60 3e-08
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 60 3e-08
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 59 5e-08
BC132983-1|AAI32984.1| 313|Homo sapiens leucine rich repeat con... 59 5e-08
BC132981-1|AAI32982.1| 313|Homo sapiens leucine rich repeat con... 59 5e-08
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 59 5e-08
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 59 5e-08
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 59 5e-08
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 59 5e-08
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 59 5e-08
AL157714-2|CAI15338.1| 313|Homo sapiens novel protein protein. 59 5e-08
AK098677-1|BAC05375.1| 313|Homo sapiens protein ( Homo sapiens ... 59 5e-08
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 59 5e-08
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 59 5e-08
BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein. 58 6e-08
AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat con... 58 6e-08
AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat con... 58 6e-08
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 58 8e-08
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 58 1e-07
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 58 1e-07
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 58 1e-07
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 58 1e-07
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 58 1e-07
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 58 1e-07
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 58 1e-07
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 58 1e-07
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 58 1e-07
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 58 1e-07
BC126156-1|AAI26157.1| 370|Homo sapiens leucine rich repeat con... 57 2e-07
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 57 2e-07
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 57 2e-07
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 57 2e-07
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 57 2e-07
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 57 2e-07
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 57 2e-07
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 57 2e-07
AK222987-1|BAD96707.1| 370|Homo sapiens leucine rich repeat con... 57 2e-07
AK024955-1|BAB15042.1| 370|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 57 2e-07
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 57 2e-07
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 57 2e-07
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 57 2e-07
U88881-1|AAC34136.1| 365|Homo sapiens Toll-like receptor 5 prot... 56 3e-07
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 56 3e-07
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 56 3e-07
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 56 3e-07
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 56 3e-07
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 56 3e-07
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 56 3e-07
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 56 3e-07
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 56 3e-07
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 56 3e-07
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 56 3e-07
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 56 3e-07
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 56 3e-07
AY090637-1|AAM09084.1| 320|Homo sapiens tumor endothelial marke... 56 3e-07
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 56 3e-07
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 56 3e-07
AK027296-1|BAB55022.1| 185|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 56 3e-07
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 56 3e-07
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 56 3e-07
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 56 3e-07
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 56 3e-07
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 56 3e-07
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 56 3e-07
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 56 3e-07
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 56 3e-07
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 56 3e-07
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 56 3e-07
BC027903-1|AAH27903.1| 441|Homo sapiens leucine rich repeat con... 56 3e-07
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 56 3e-07
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 56 3e-07
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 56 3e-07
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 56 3e-07
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 56 3e-07
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 56 4e-07
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 56 4e-07
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 56 4e-07
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 56 4e-07
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 56 4e-07
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 56 4e-07
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 56 4e-07
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 56 4e-07
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 56 4e-07
AF051152-1|AAC34377.1| 784|Homo sapiens Toll/interleukin-1 rece... 56 4e-07
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 55 6e-07
DQ864979-1|ABI23432.1| 193|Homo sapiens RTN4RL2 protein. 55 8e-07
AY358889-1|AAQ89248.1| 440|Homo sapiens p37NB protein. 55 8e-07
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 55 8e-07
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 54 1e-06
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 54 1e-06
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 54 1e-06
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 54 1e-06
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 54 1e-06
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 54 1e-06
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 54 1e-06
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 54 1e-06
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 54 1e-06
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 54 2e-06
BC019687-1|AAH19687.1| 430|Homo sapiens LRRC4B protein protein. 52 4e-06
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 52 4e-06
AF502291-1|AAM23001.1| 586|Homo sapiens toll-like receptor 2 pr... 52 4e-06
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 52 4e-06
BC110418-1|AAI10419.1| 504|Homo sapiens adhesion molecule with ... 51 9e-06
BC101365-1|AAI01366.1| 504|Homo sapiens adhesion molecule with ... 51 9e-06
BC101364-1|AAI01365.1| 504|Homo sapiens adhesion molecule with ... 51 9e-06
BC101363-1|AAI01364.1| 504|Homo sapiens adhesion molecule with ... 51 9e-06
AY358134-1|AAQ88501.1| 504|Homo sapiens TWLV6084 protein. 51 9e-06
AY237003-1|AAO48944.1| 504|Homo sapiens transmembrane protein A... 51 9e-06
AB058754-1|BAB47480.1| 523|Homo sapiens KIAA1851 protein protein. 51 9e-06
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 51 1e-05
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 51 1e-05
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 51 1e-05
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 51 1e-05
U32907-1|AAB41565.1| 313|Homo sapiens p37NB protein. 50 2e-05
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 50 2e-05
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 50 2e-05
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 50 2e-05
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 50 2e-05
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 50 2e-05
AC073127-2|AAS07483.1| 313|Homo sapiens unknown protein. 50 2e-05
BC037982-1|AAH37982.1| 685|Homo sapiens leucine rich repeat con... 49 4e-05
AY386262-1|AAR28083.1| 820|Homo sapiens c114 SLIT-like testicul... 49 4e-05
AK127591-1|BAC87047.1| 341|Homo sapiens protein ( Homo sapiens ... 49 4e-05
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 122 bits (294), Expect = 3e-27
Identities = 113/425 (26%), Positives = 177/425 (41%), Gaps = 18/425 (4%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
EA G CP C C+ D +E V C ++ +P D + + + D N
Sbjct: 35 EAEGPACPAACVCSYDDDADE---LSVFCSSRNLTRLP-DGVPGGTQALWL----DGNNL 86
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQF---SFWGLQNLRVLNLTHNNLTSVVADN 126
++ PA F NL L +N +G + GL+NL L+L N L S+
Sbjct: 87 SSV-----PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGT 141
Query: 127 FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
F L L L +N + ++ F L SL L L N ++ L FR L L L L
Sbjct: 142 FAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVL 201
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
+ N L L P +F + LR R LR I ++ +PRL++L L NL +
Sbjct: 202 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 261
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
F+ LK L+ L L N+++ ++++ F L VL LS N +
Sbjct: 262 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQL 321
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
HN+I + ++F + L+ + N L + L L + + L+ L+ +P+
Sbjct: 322 GHNRIRQLAERSFEG-LGQLEVLTLDHNQLQEVKAGAFLG-LTNVAVMNLSGNCLRNLPE 379
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
F L +L L + L R + L+RL + N L + EQ L L + E+
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 427 NLMKN 431
+L N
Sbjct: 440 DLTSN 444
Score = 105 bits (253), Expect = 3e-22
Identities = 73/252 (28%), Positives = 118/252 (46%), Gaps = 1/252 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L + ++ V + + +F GL LRVL L+HN + S+ F+ L L EL L HN I
Sbjct: 268 LRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 327
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
Q++ +F L L+ L L +NQ+ + + F L +++++LS N L +L +VF+ +
Sbjct: 328 QLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGK 387
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L RI + + L L L +N + L L +L L NQL+
Sbjct: 388 LHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLT 447
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ +F +L L LSRNR D+SHN+++ AP +
Sbjct: 448 HLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP-LG 506
Query: 325 SLKTINFSGNNL 336
L+ ++ N+L
Sbjct: 507 RLRYLSLRNNSL 518
Score = 103 bits (246), Expect = 2e-21
Identities = 88/352 (25%), Positives = 160/352 (45%), Gaps = 6/352 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LREL + + + + F GL LR L+L+ N L ++ A+ F L L +L+LD N I
Sbjct: 195 SLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLI 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ F L +L+ L L++N+++ L+ F L L +L LS N + L P FKD+
Sbjct: 255 AAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLH 314
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + +R++ + + + +LE L L N + + + F+ L + + L GN L
Sbjct: 315 FLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCL 374
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + +F +LH L L + + N + Q+ +
Sbjct: 375 RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLA 434
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ + N L + + Q L ++ + L+ L E+P + + LD+S N
Sbjct: 435 ELLE-LDLTSNQL-THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
+L P LL+ L+ L + +N L+T + Q + + L N W C
Sbjct: 493 RLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDC 540
Score = 102 bits (244), Expect = 4e-21
Identities = 96/348 (27%), Positives = 148/348 (42%), Gaps = 2/348 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + S+ +F L L L++N L+ + F GL +L +L+L N +
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ FR L SL+ L+LA N+++ L LF LA+L LDLS N L + VF +
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ R L+ + + + L LDL N L D F L L+ L+L N +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L L NR + HN++ F +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
++ +N SGN L N V + L ++H + L L I + FT L L L N
Sbjct: 363 -NVAVMNLSGNCL-RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L LD++ N+L L + Q L + + L +N
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 5/252 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ LR L + ++ + S+ +F L L L L HN + + +F GL L L LDHN
Sbjct: 290 LGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQ 349
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ + F LT++ + L+ N + L ++FR L KL L L + L + P F +
Sbjct: 350 LQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 409
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
LR + L I Q + L ELDL N +L F L +L+ L L N+
Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 469
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
L+ + + G + L +S NR + +N L+TF P
Sbjct: 470 LAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNS-----LRTFTPQ 524
Query: 323 VDSLKTINFSGN 334
L+ + GN
Sbjct: 525 PPGLERLWLEGN 536
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 122 bits (294), Expect = 3e-27
Identities = 113/425 (26%), Positives = 177/425 (41%), Gaps = 18/425 (4%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
EA G CP C C+ D +E V C ++ +P D + + + D N
Sbjct: 35 EAEGPACPAACVCSYDDDADE---LSVFCSSRNLTRLP-DGVPGGTQALWL----DGNNL 86
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQF---SFWGLQNLRVLNLTHNNLTSVVADN 126
++ PA F NL L +N +G + GL+NL L+L N L S+
Sbjct: 87 SSV-----PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGT 141
Query: 127 FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
F L L L +N + ++ F L SL L L N ++ L FR L L L L
Sbjct: 142 FAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVL 201
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
+ N L L P +F + LR R LR I ++ +PRL++L L NL +
Sbjct: 202 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 261
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
F+ LK L+ L L N+++ ++++ F L VL LS N +
Sbjct: 262 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQL 321
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
HN+I + ++F + L+ + N L + L L + + L+ L+ +P+
Sbjct: 322 GHNRIRQLAERSFEG-LGQLEVLTLDHNQLQEVKAGAFLG-LTNVAVMNLSGNCLRNLPE 379
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
F L +L L + L R + L+RL + N L + EQ L L + E+
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 427 NLMKN 431
+L N
Sbjct: 440 DLTSN 444
Score = 105 bits (253), Expect = 3e-22
Identities = 73/252 (28%), Positives = 118/252 (46%), Gaps = 1/252 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L + ++ V + + +F GL LRVL L+HN + S+ F+ L L EL L HN I
Sbjct: 268 LRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 327
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
Q++ +F L L+ L L +NQ+ + + F L +++++LS N L +L +VF+ +
Sbjct: 328 QLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGK 387
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L RI + + L L L +N + L L +L L NQL+
Sbjct: 388 LHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLT 447
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ +F +L L LSRNR D+SHN+++ AP +
Sbjct: 448 HLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP-LG 506
Query: 325 SLKTINFSGNNL 336
L+ ++ N+L
Sbjct: 507 RLRYLSLRNNSL 518
Score = 103 bits (246), Expect = 2e-21
Identities = 88/352 (25%), Positives = 160/352 (45%), Gaps = 6/352 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LREL + + + + F GL LR L+L+ N L ++ A+ F L L +L+LD N I
Sbjct: 195 SLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLI 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ F L +L+ L L++N+++ L+ F L L +L LS N + L P FKD+
Sbjct: 255 AAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLH 314
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + +R++ + + + +LE L L N + + + F+ L + + L GN L
Sbjct: 315 FLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCL 374
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + +F +LH L L + + N + Q+ +
Sbjct: 375 RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLA 434
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ + N L + + Q L ++ + L+ L E+P + + LD+S N
Sbjct: 435 ELLE-LDLTSNQL-THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
+L P LL+ L+ L + +N L+T + Q + + L N W C
Sbjct: 493 RLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDC 540
Score = 102 bits (244), Expect = 4e-21
Identities = 96/348 (27%), Positives = 148/348 (42%), Gaps = 2/348 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + S+ +F L L L++N L+ + F GL +L +L+L N +
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ FR L SL+ L+LA N+++ L LF LA+L LDLS N L + VF +
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ R L+ + + + L LDL N L D F L L+ L+L N +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L L NR + HN++ F +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
++ +N SGN L N V + L ++H + L L I + FT L L L N
Sbjct: 363 -NVAVMNLSGNCL-RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L LD++ N+L L + Q L + + L +N
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 5/252 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ LR L + ++ + S+ +F L L L L HN + + +F GL L L LDHN
Sbjct: 290 LGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQ 349
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ + F LT++ + L+ N + L ++FR L KL L L + L + P F +
Sbjct: 350 LQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 409
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
LR + L I Q + L ELDL N +L F L +L+ L L N+
Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 469
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
L+ + + G + L +S NR + +N L+TF P
Sbjct: 470 LAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNS-----LRTFTPQ 524
Query: 323 VDSLKTINFSGN 334
L+ + GN
Sbjct: 525 PPGLERLWLEGN 536
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 122 bits (294), Expect = 3e-27
Identities = 113/425 (26%), Positives = 177/425 (41%), Gaps = 18/425 (4%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
EA G CP C C+ D +E V C ++ +P D + + + D N
Sbjct: 35 EAEGPACPAACVCSYDDDADE---LSVFCSSRNLTRLP-DGVPGGTQALWL----DGNNL 86
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQF---SFWGLQNLRVLNLTHNNLTSVVADN 126
++ PA F NL L +N +G + GL+NL L+L N L S+
Sbjct: 87 SSV-----PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGT 141
Query: 127 FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
F L L L +N + ++ F L SL L L N ++ L FR L L L L
Sbjct: 142 FAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVL 201
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
+ N L L P +F + LR R LR I ++ +PRL++L L NL +
Sbjct: 202 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 261
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
F+ LK L+ L L N+++ ++++ F L VL LS N +
Sbjct: 262 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQL 321
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
HN+I + ++F + L+ + N L + L L + + L+ L+ +P+
Sbjct: 322 GHNRIRQLAERSFEG-LGQLEVLTLDHNQLQEVKAGAFLG-LTNVAVMNLSGNCLRNLPE 379
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
F L +L L + L R + L+RL + N L + EQ L L + E+
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 427 NLMKN 431
+L N
Sbjct: 440 DLTSN 444
Score = 105 bits (253), Expect = 3e-22
Identities = 73/252 (28%), Positives = 118/252 (46%), Gaps = 1/252 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L + ++ V + + +F GL LRVL L+HN + S+ F+ L L EL L HN I
Sbjct: 268 LRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 327
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
Q++ +F L L+ L L +NQ+ + + F L +++++LS N L +L +VF+ +
Sbjct: 328 QLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGK 387
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L RI + + L L L +N + L L +L L NQL+
Sbjct: 388 LHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLT 447
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ +F +L L LSRNR D+SHN+++ AP +
Sbjct: 448 HLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP-LG 506
Query: 325 SLKTINFSGNNL 336
L+ ++ N+L
Sbjct: 507 RLRYLSLRNNSL 518
Score = 103 bits (246), Expect = 2e-21
Identities = 88/352 (25%), Positives = 160/352 (45%), Gaps = 6/352 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LREL + + + + F GL LR L+L+ N L ++ A+ F L L +L+LD N I
Sbjct: 195 SLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLI 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ F L +L+ L L++N+++ L+ F L L +L LS N + L P FKD+
Sbjct: 255 AAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLH 314
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + +R++ + + + +LE L L N + + + F+ L + + L GN L
Sbjct: 315 FLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCL 374
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + +F +LH L L + + N + Q+ +
Sbjct: 375 RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLA 434
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ + N L + + Q L ++ + L+ L E+P + + LD+S N
Sbjct: 435 ELLE-LDLTSNQL-THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
+L P LL+ L+ L + +N L+T + Q + + L N W C
Sbjct: 493 RLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDC 540
Score = 102 bits (244), Expect = 4e-21
Identities = 96/348 (27%), Positives = 148/348 (42%), Gaps = 2/348 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + S+ +F L L L++N L+ + F GL +L +L+L N +
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ FR L SL+ L+LA N+++ L LF LA+L LDLS N L + VF +
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ R L+ + + + L LDL N L D F L L+ L+L N +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L L NR + HN++ F +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
++ +N SGN L N V + L ++H + L L I + FT L L L N
Sbjct: 363 -NVAVMNLSGNCL-RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L LD++ N+L L + Q L + + L +N
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 5/252 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ LR L + ++ + S+ +F L L L L HN + + +F GL L L LDHN
Sbjct: 290 LGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQ 349
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ + F LT++ + L+ N + L ++FR L KL L L + L + P F +
Sbjct: 350 LQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 409
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
LR + L I Q + L ELDL N +L F L +L+ L L N+
Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 469
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
L+ + + G + L +S NR + +N L+TF P
Sbjct: 470 LAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNS-----LRTFTPQ 524
Query: 323 VDSLKTINFSGN 334
L+ + GN
Sbjct: 525 PPGLERLWLEGN 536
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 121 bits (292), Expect = 6e-27
Identities = 113/425 (26%), Positives = 177/425 (41%), Gaps = 18/425 (4%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
EA G CP C C+ D +E V C ++ +P D + + + D N
Sbjct: 35 EAEGPACPAACVCSYDDDADE---LSVFCSSRNLTRLP-DGVPGGTQALWL----DGNNL 86
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQF---SFWGLQNLRVLNLTHNNLTSVVADN 126
++ PA F NL L +N +G + GL+NL L+L N L S+
Sbjct: 87 SSV-----PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGT 141
Query: 127 FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
F L L L +N + ++ F L SL L L N ++ L FR L L L L
Sbjct: 142 FAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVL 201
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
+ N L L P +F + LR R LR I ++ +PRL++L L NL +
Sbjct: 202 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 261
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
F+ LK L+ L L N+++ ++++ F L VL LS N +
Sbjct: 262 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQL 321
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
HN+I + ++F + L+ + N L + L L + + L+ L+ +P+
Sbjct: 322 GHNRIRQLAERSFEG-LGQLEVLTLDHNQLQEVKAGAFLG-LTNMAVMNLSGNCLRNLPE 379
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
F L +L L + L R + L+RL + N L + EQ L L + E+
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 427 NLMKN 431
+L N
Sbjct: 440 DLTSN 444
Score = 106 bits (254), Expect = 2e-22
Identities = 73/252 (28%), Positives = 118/252 (46%), Gaps = 1/252 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L + ++ V + + +F GL LRVL L+HN + S+ F+ L L EL L HN I
Sbjct: 268 LRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 327
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
Q++ +F L L+ L L +NQ+ + + F L +++++LS N L +L +VF+ +
Sbjct: 328 QLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGK 387
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L RI + + L L L +N + L L +L L NQL+
Sbjct: 388 LHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLT 447
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ +F +L L LSRNR D+SHN+++ AP +
Sbjct: 448 HLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP-LG 506
Query: 325 SLKTINFSGNNL 336
L+ ++ N+L
Sbjct: 507 RLRYLSLRNNSL 518
Score = 103 bits (247), Expect = 2e-21
Identities = 88/352 (25%), Positives = 160/352 (45%), Gaps = 6/352 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LREL + + + + F GL LR L+L+ N L ++ A+ F L L +L+LD N I
Sbjct: 195 SLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLI 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ F L +L+ L L++N+++ L+ F L L +L LS N + L P FKD+
Sbjct: 255 AAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLH 314
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + +R++ + + + +LE L L N + + + F+ L + + L GN L
Sbjct: 315 FLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCL 374
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + +F +LH L L + + N + Q+ +
Sbjct: 375 RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLA 434
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ + N L + + Q L ++ + L+ L E+P + + LD+S N
Sbjct: 435 ELLE-LDLTSNQL-THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHN 492
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
+L P LL+ L+ L + +N L+T + Q + + L N W C
Sbjct: 493 RLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQP----PGLERLWLEGNPWDC 540
Score = 102 bits (245), Expect = 3e-21
Identities = 96/348 (27%), Positives = 148/348 (42%), Gaps = 2/348 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + S+ +F L L L++N L+ + F GL +L +L+L N +
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ FR L SL+ L+LA N+++ L LF LA+L LDLS N L + VF +
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ R L+ + + + L LDL N L D F L L+ L+L N +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L L NR + HN++ F +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
++ +N SGN L N V + L ++H + L L I + FT L L L N
Sbjct: 363 -NMAVMNLSGNCL-RNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L LD++ N+L L + Q L + + L +N
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRN 468
Score = 84.6 bits (200), Expect = 8e-16
Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 5/252 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ LR L + ++ + S+ +F L L L L HN + + +F GL L L LDHN
Sbjct: 290 LGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQ 349
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ + F LT++ + L+ N + L ++FR L KL L L + L + P F +
Sbjct: 350 LQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 409
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
LR + L I Q + L ELDL N +L F L +L+ L L N+
Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 469
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
L+ + + G + L +S NR + +N L+TF P
Sbjct: 470 LAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNS-----LRTFTPQ 524
Query: 323 VDSLKTINFSGN 334
L+ + GN
Sbjct: 525 PPGLERLWLEGN 536
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 119 bits (286), Expect = 3e-26
Identities = 76/225 (33%), Positives = 111/225 (49%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N+L + + F+GL LT L+LDHNHI + F + LK LIL++N+IS +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ FR + L LDLS N L L E F+ ++ L R LR I +I+ LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L + F + RLK+L L+ NQ S + +F R L L L N+
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N+I+ F + V +L+ +N N L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/183 (34%), Positives = 92/183 (50%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F GL L L L HN+++++ + F G+ L EL L N I + TFR +T+L+ L L
Sbjct: 81 FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDL 140
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ NQ+ +L S FR L KL L L N L + +F+D ++L + +R + +
Sbjct: 141 SYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNV 200
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + RL+EL L N F L F L L+ L L N++SVI M L L L
Sbjct: 201 FAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDL 260
Query: 283 SRN 285
S N
Sbjct: 261 SGN 263
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/176 (26%), Positives = 89/176 (50%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++++ +I + +F G++ L+ L L+ N ++ + + FR + NL L L +N + +
Sbjct: 90 LYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE FR L L +L L +N + T+ R+F+ L +LDL N + L VF + L+
Sbjct: 150 SEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++N ++ + L+ L L N + + L++L L GN++
Sbjct: 210 LHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Score = 72.1 bits (169), Expect = 5e-12
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + +F + NLR L+L++N L S+ ++ FRGL L LHL N +
Sbjct: 111 LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L+ L L N+I +L +F + +L L L N + LN +F +
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ + + I + L+ LDL G + + F + L++L LD N+L
Sbjct: 231 LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ I + L+ ++L+ N
Sbjct: 291 TFIGQEILDSWISLNDISLAGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ ++++ +I F +NL +L+L +N + S+ + F G+I L ELHL+HN
Sbjct: 159 LLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN-PEVFKDIQ 203
+++ F L SL+ L L N+IS + + + L LDLS N + + P VF+ +
Sbjct: 219 KLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVP 278
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+L+ L I +I L ++ L N+++
Sbjct: 279 NLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWE 315
Score = 70.1 bits (164), Expect = 2e-11
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 9/289 (3%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L L FK + L + I+ ++ + RL+EL L N Y
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
++ F + L+ L L NQL + F R+L L L N
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+ +N+I FA ++ LK ++ N +A+ +++ + + L +
Sbjct: 186 LDLGYNRIRSLARNVFAGMI-RLKELHLEHNQFSKLNLALFPRLV-SLQNLYLQWNKISV 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPF-KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I Q L LDLS N++ F + LQRL++ NKL + ++ L +
Sbjct: 244 IGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWIS 303
Query: 423 IAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ +++L N W C + CS N L N+ I C SP L+G
Sbjct: 304 LNDISLAGNIWECSRNICSLVNWLKSFKGLRENTII----CASPKELQG 348
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + S+G F GL+ L L+L N+L ++ F+ NL L L +
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I ++ F + LK L L +NQ S L LF L L L L N ++ + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 201 DIQHLRIFKCRRCLLRRIN-TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
L+ + + ++ VP L+ L+L N ++ + S L + L
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 260 GN 261
GN
Sbjct: 311 GN 312
Score = 33.1 bits (72), Expect = 2.7
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A + L+ELH+ ++ + F L +L+ L L N ++ + +L L L
Sbjct: 202 AGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLS 261
Query: 140 HNHIEQMSS-ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N IE S F+ + +L+ L L +N+++ + + L+ + L+ N + + + +
Sbjct: 262 GNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN-IWECSRNI 320
Query: 199 FKDIQHLRIFK 209
+ L+ FK
Sbjct: 321 CSLVNWLKSFK 331
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 119 bits (286), Expect = 3e-26
Identities = 76/225 (33%), Positives = 111/225 (49%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N+L + + F+GL LT L+LDHNHI + F + LK LIL++N+IS +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ FR + L LDLS N L L E F+ ++ L R LR I +I+ LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L + F + RLK+L L+ NQ S + +F R L L L N+
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N+I+ F + V +L+ +N N L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/183 (34%), Positives = 92/183 (50%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F GL L L L HN+++++ + F G+ L EL L N I + TFR +T+L+ L L
Sbjct: 81 FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDL 140
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ NQ+ +L S FR L KL L L N L + +F+D ++L + +R + +
Sbjct: 141 SYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNV 200
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + RL+EL L N F L F L L+ L L N++SVI M L L L
Sbjct: 201 FAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDL 260
Query: 283 SRN 285
S N
Sbjct: 261 SGN 263
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/176 (26%), Positives = 89/176 (50%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++++ +I + +F G++ L+ L L+ N ++ + + FR + NL L L +N + +
Sbjct: 90 LYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE FR L L +L L +N + T+ R+F+ L +LDL N + L VF + L+
Sbjct: 150 SEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++N ++ + L+ L L N + + L++L L GN++
Sbjct: 210 LHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Score = 72.1 bits (169), Expect = 5e-12
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + +F + NLR L+L++N L S+ ++ FRGL L LHL N +
Sbjct: 111 LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L+ L L N+I +L +F + +L L L N + LN +F +
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ + + I + L+ LDL G + + F + L++L LD N+L
Sbjct: 231 LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ I + L+ ++L+ N
Sbjct: 291 TFIGQEILDSWISLNDISLAGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ ++++ +I F +NL +L+L +N + S+ + F G+I L ELHL+HN
Sbjct: 159 LLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN-PEVFKDIQ 203
+++ F L SL+ L L N+IS + + + L LDLS N + + P VF+ +
Sbjct: 219 KLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVP 278
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+L+ L I +I L ++ L N+++
Sbjct: 279 NLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWE 315
Score = 70.1 bits (164), Expect = 2e-11
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 9/289 (3%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L L FK + L + I+ ++ + RL+EL L N Y
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
++ F + L+ L L NQL + F R+L L L N
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+ +N+I FA ++ LK ++ N +A+ +++ + + L +
Sbjct: 186 LDLGYNRIRSLARNVFAGMI-RLKELHLEHNQFSKLNLALFPRLV-SLQNLYLQWNKISV 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPF-KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I Q L LDLS N++ F + LQRL++ NKL + ++ L +
Sbjct: 244 IGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWIS 303
Query: 423 IAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ +++L N W C + CS N L N+ I C SP L+G
Sbjct: 304 LNDISLAGNIWECSRNICSLVNWLKSFKGLRENTII----CASPKELQG 348
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + S+G F GL+ L L+L N+L ++ F+ NL L L +
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I ++ F + LK L L +NQ S L LF L L L L N ++ + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 201 DIQHLRIFKCRRCLLRRIN-TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
L+ + + ++ VP L+ L+L N ++ + S L + L
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 260 GN 261
GN
Sbjct: 311 GN 312
Score = 33.1 bits (72), Expect = 2.7
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A + L+ELH+ ++ + F L +L+ L L N ++ + +L L L
Sbjct: 202 AGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLS 261
Query: 140 HNHIEQMSS-ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N IE S F+ + +L+ L L +N+++ + + L+ + L+ N + + + +
Sbjct: 262 GNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN-IWECSRNI 320
Query: 199 FKDIQHLRIFK 209
+ L+ FK
Sbjct: 321 CSLVNWLKSFK 331
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 119 bits (286), Expect = 3e-26
Identities = 76/225 (33%), Positives = 111/225 (49%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N+L + + F+GL LT L+LDHNHI + F + LK LIL++N+IS +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ FR + L LDLS N L L E F+ ++ L R LR I +I+ LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L + F + RLK+L L+ NQ S + +F R L L L N+
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N+I+ F + V +L+ +N N L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/183 (34%), Positives = 92/183 (50%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F GL L L L HN+++++ + F G+ L EL L N I + TFR +T+L+ L L
Sbjct: 81 FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDL 140
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ NQ+ +L S FR L KL L L N L + +F+D ++L + +R + +
Sbjct: 141 SYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNV 200
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + RL+EL L N F L F L L+ L L N++SVI M L L L
Sbjct: 201 FAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDL 260
Query: 283 SRN 285
S N
Sbjct: 261 SGN 263
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/176 (26%), Positives = 89/176 (50%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++++ +I + +F G++ L+ L L+ N ++ + + FR + NL L L +N + +
Sbjct: 90 LYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE FR L L +L L +N + T+ R+F+ L +LDL N + L VF + L+
Sbjct: 150 SEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++N ++ + L+ L L N + + L++L L GN++
Sbjct: 210 LHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Score = 72.1 bits (169), Expect = 5e-12
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + +F + NLR L+L++N L S+ ++ FRGL L LHL N +
Sbjct: 111 LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L+ L L N+I +L +F + +L L L N + LN +F +
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ + + I + L+ LDL G + + F + L++L LD N+L
Sbjct: 231 LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ I + L+ ++L+ N
Sbjct: 291 TFIGQEILDSWISLNDISLAGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ ++++ +I F +NL +L+L +N + S+ + F G+I L ELHL+HN
Sbjct: 159 LLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN-PEVFKDIQ 203
+++ F L SL+ L L N+IS + + + L LDLS N + + P VF+ +
Sbjct: 219 KLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVP 278
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+L+ L I +I L ++ L N+++
Sbjct: 279 NLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWE 315
Score = 70.1 bits (164), Expect = 2e-11
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 9/289 (3%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L L FK + L + I+ ++ + RL+EL L N Y
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
++ F + L+ L L NQL + F R+L L L N
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+ +N+I FA ++ LK ++ N +A+ +++ + + L +
Sbjct: 186 LDLGYNRIRSLARNVFAGMI-RLKELHLEHNQFSKLNLALFPRLV-SLQNLYLQWNKISV 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPF-KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I Q L LDLS N++ F + LQRL++ NKL + ++ L +
Sbjct: 244 IGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWIS 303
Query: 423 IAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ +++L N W C + CS N L N+ I C SP L+G
Sbjct: 304 LNDISLAGNIWECSRNICSLVNWLKSFKGLRENTII----CASPKELQG 348
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + S+G F GL+ L L+L N+L ++ F+ NL L L +
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I ++ F + LK L L +NQ S L LF L L L L N ++ + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 201 DIQHLRIFKCRRCLLRRIN-TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
L+ + + ++ VP L+ L+L N ++ + S L + L
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 260 GN 261
GN
Sbjct: 311 GN 312
Score = 33.1 bits (72), Expect = 2.7
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A + L+ELH+ ++ + F L +L+ L L N ++ + +L L L
Sbjct: 202 AGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLS 261
Query: 140 HNHIEQMSS-ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N IE S F+ + +L+ L L +N+++ + + L+ + L+ N + + + +
Sbjct: 262 GNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN-IWECSRNI 320
Query: 199 FKDIQHLRIFK 209
+ L+ FK
Sbjct: 321 CSLVNWLKSFK 331
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 119 bits (286), Expect = 3e-26
Identities = 76/225 (33%), Positives = 111/225 (49%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N+L + + F+GL LT L+LDHNHI + F + LK LIL++N+IS +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ FR + L LDLS N L L E F+ ++ L R LR I +I+ LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L + F + RLK+L L+ NQ S + +F R L L L N+
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N+I+ F + V +L+ +N N L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/183 (34%), Positives = 92/183 (50%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F GL L L L HN+++++ + F G+ L EL L N I + TFR +T+L+ L L
Sbjct: 81 FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDL 140
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ NQ+ +L S FR L KL L L N L + +F+D ++L + +R + +
Sbjct: 141 SYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNV 200
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + RL+EL L N F L F L L+ L L N++SVI M L L L
Sbjct: 201 FAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDL 260
Query: 283 SRN 285
S N
Sbjct: 261 SGN 263
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/176 (26%), Positives = 89/176 (50%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++++ +I + +F G++ L+ L L+ N ++ + + FR + NL L L +N + +
Sbjct: 90 LYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE FR L L +L L +N + T+ R+F+ L +LDL N + L VF + L+
Sbjct: 150 SEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++N ++ + L+ L L N + + L++L L GN++
Sbjct: 210 LHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Score = 72.1 bits (169), Expect = 5e-12
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + +F + NLR L+L++N L S+ ++ FRGL L LHL N +
Sbjct: 111 LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L+ L L N+I +L +F + +L L L N + LN +F +
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ + + I + L+ LDL G + + F + L++L LD N+L
Sbjct: 231 LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ I + L+ ++L+ N
Sbjct: 291 TFIGQEILDSWISLNDISLAGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ ++++ +I F +NL +L+L +N + S+ + F G+I L ELHL+HN
Sbjct: 159 LLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN-PEVFKDIQ 203
+++ F L SL+ L L N+IS + + + L LDLS N + + P VF+ +
Sbjct: 219 KLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVP 278
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+L+ L I +I L ++ L N+++
Sbjct: 279 NLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWE 315
Score = 70.1 bits (164), Expect = 2e-11
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 9/289 (3%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L L FK + L + I+ ++ + RL+EL L N Y
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
++ F + L+ L L NQL + F R+L L L N
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+ +N+I FA ++ LK ++ N +A+ +++ + + L +
Sbjct: 186 LDLGYNRIRSLARNVFAGMI-RLKELHLEHNQFSKLNLALFPRLV-SLQNLYLQWNKISV 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPF-KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I Q L LDLS N++ F + LQRL++ NKL + ++ L +
Sbjct: 244 IGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWIS 303
Query: 423 IAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ +++L N W C + CS N L N+ I C SP L+G
Sbjct: 304 LNDISLAGNIWECSRNICSLVNWLKSFKGLRENTII----CASPKELQG 348
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + S+G F GL+ L L+L N+L ++ F+ NL L L +
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I ++ F + LK L L +NQ S L LF L L L L N ++ + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 201 DIQHLRIFKCRRCLLRRIN-TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
L+ + + ++ VP L+ L+L N ++ + S L + L
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 260 GN 261
GN
Sbjct: 311 GN 312
Score = 33.1 bits (72), Expect = 2.7
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A + L+ELH+ ++ + F L +L+ L L N ++ + +L L L
Sbjct: 202 AGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLS 261
Query: 140 HNHIEQMSS-ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N IE S F+ + +L+ L L +N+++ + + L+ + L+ N + + + +
Sbjct: 262 GNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN-IWECSRNI 320
Query: 199 FKDIQHLRIFK 209
+ L+ FK
Sbjct: 321 CSLVNWLKSFK 331
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 119 bits (286), Expect = 3e-26
Identities = 76/225 (33%), Positives = 111/225 (49%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N+L + + F+GL LT L+LDHNHI + F + LK LIL++N+IS +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ FR + L LDLS N L L E F+ ++ L R LR I +I+ LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L + F + RLK+L L+ NQ S + +F R L L L N+
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N+I+ F + V +L+ +N N L
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Score = 93.1 bits (221), Expect = 2e-18
Identities = 63/183 (34%), Positives = 92/183 (50%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F GL L L L HN+++++ + F G+ L EL L N I + TFR +T+L+ L L
Sbjct: 81 FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDL 140
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ NQ+ +L S FR L KL L L N L + +F+D ++L + +R + +
Sbjct: 141 SYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNV 200
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + RL+EL L N F L F L L+ L L N++SVI M L L L
Sbjct: 201 FAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDL 260
Query: 283 SRN 285
S N
Sbjct: 261 SGN 263
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/176 (26%), Positives = 89/176 (50%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++++ +I + +F G++ L+ L L+ N ++ + + FR + NL L L +N + +
Sbjct: 90 LYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE FR L L +L L +N + T+ R+F+ L +LDL N + L VF + L+
Sbjct: 150 SEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++N ++ + L+ L L N + + L++L L GN++
Sbjct: 210 LHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Score = 72.1 bits (169), Expect = 5e-12
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + +F + NLR L+L++N L S+ ++ FRGL L LHL N +
Sbjct: 111 LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L+ L L N+I +L +F + +L L L N + LN +F +
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ + + I + L+ LDL G + + F + L++L LD N+L
Sbjct: 231 LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ I + L+ ++L+ N
Sbjct: 291 TFIGQEILDSWISLNDISLAGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ ++++ +I F +NL +L+L +N + S+ + F G+I L ELHL+HN
Sbjct: 159 LLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN-PEVFKDIQ 203
+++ F L SL+ L L N+IS + + + L LDLS N + + P VF+ +
Sbjct: 219 KLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVP 278
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+L+ L I +I L ++ L N+++
Sbjct: 279 NLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWE 315
Score = 70.1 bits (164), Expect = 2e-11
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 9/289 (3%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L L FK + L + I+ ++ + RL+EL L N Y
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
++ F + L+ L L NQL + F R+L L L N
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+ +N+I FA ++ LK ++ N +A+ +++ + + L +
Sbjct: 186 LDLGYNRIRSLARNVFAGMI-RLKELHLEHNQFSKLNLALFPRLV-SLQNLYLQWNKISV 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPF-KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I Q L LDLS N++ F + LQRL++ NKL + ++ L +
Sbjct: 244 IGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWIS 303
Query: 423 IAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ +++L N W C + CS N L N+ I C SP L+G
Sbjct: 304 LNDISLAGNIWECSRNICSLVNWLKSFKGLRENTII----CASPKELQG 348
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + S+G F GL+ L L+L N+L ++ F+ NL L L +
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I ++ F + LK L L +NQ S L LF L L L L N ++ + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 201 DIQHLRIFKCRRCLLRRIN-TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
L+ + + ++ VP L+ L+L N ++ + S L + L
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 260 GN 261
GN
Sbjct: 311 GN 312
Score = 33.1 bits (72), Expect = 2.7
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A + L+ELH+ ++ + F L +L+ L L N ++ + +L L L
Sbjct: 202 AGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLS 261
Query: 140 HNHIEQMSS-ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N IE S F+ + +L+ L L +N+++ + + L+ + L+ N + + + +
Sbjct: 262 GNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN-IWECSRNI 320
Query: 199 FKDIQHLRIFK 209
+ L+ FK
Sbjct: 321 CSLVNWLKSFK 331
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 117 bits (282), Expect = 1e-25
Identities = 81/246 (32%), Positives = 120/246 (48%), Gaps = 2/246 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L HN++T + D F LT LHLDHN I + + F+ L LK LIL++N+I L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L LDLS N L+ L+PE+F ++ L+ R LR I +++ LE
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N + L + F L +L++L L+ NQL+ I F R LH L L N+
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D++ N+I L F + +LK + N L + + +L L +
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVF-ETMPNLKILLMDNNKLNSLD-SKILNSLRSL 303
Query: 352 HGVGLA 357
VGL+
Sbjct: 304 TTVGLS 309
Score = 85.4 bits (202), Expect = 5e-16
Identities = 64/209 (30%), Positives = 94/209 (44%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q A F L LH+ ++ + ++ + +F GL L+ L L+ N + + F LINL L
Sbjct: 80 QFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLD 139
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N + + E F L L+TL L +N + T+ RLF L LDLS N L L
Sbjct: 140 LSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 199
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + LR L +IN + + L L L N LT + L+KL
Sbjct: 200 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLD 259
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L GN++ I +F L +L + N+
Sbjct: 260 LTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Score = 83.8 bits (198), Expect = 1e-15
Identities = 49/156 (31%), Positives = 87/156 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ LH+ ++++ +I FW ++L L+L+ N L S+ + F GLI L ELHL+HN +
Sbjct: 159 LQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLT 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+++ F L+SL TL L N+IS L + L LDL+ N + ++ VF+ + +
Sbjct: 219 KINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPN 278
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
L+I L ++++I + + L + L NL++
Sbjct: 279 LKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
Score = 82.6 bits (195), Expect = 3e-15
Identities = 67/247 (27%), Positives = 106/247 (42%), Gaps = 1/247 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++++ + + F L L+L HN +++V D F+GL L EL L N I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ TF L +L+ L L+ NQ+S+L LF L KL L L N L + +F D + L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
LR + + + +L EL L N + F+ L L L L N++S +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
M L L L+ N + +NK++ + + SL
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNS-LRSLT 304
Query: 328 TINFSGN 334
T+ SGN
Sbjct: 305 TVGLSGN 311
Score = 66.5 bits (155), Expect = 2e-10
Identities = 68/288 (23%), Positives = 112/288 (38%), Gaps = 8/288 (2%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N +T+L + F L + + + + +L+EL L N YL
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ F L L+ L L NQLS + +F R+L L L N
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+S N++ FA ++ L+ ++ N L A L+ L +H + L +
Sbjct: 186 LDLSTNRLRSLARNGFAGLI-KLRELHLEHNQLTKINFAHFLR-LSSLHTLFLQWNKISN 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ L LDL+ N++ + L+ L + +NKL +L + L L ++
Sbjct: 244 LTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSL 303
Query: 424 AEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
V L N W C C+ ++ L +S + CHSP +G
Sbjct: 304 TTVGLSGNLWECSARICALASWLGSFQGRWEHSIL----CHSPDHTQG 347
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 117 bits (282), Expect = 1e-25
Identities = 81/246 (32%), Positives = 120/246 (48%), Gaps = 2/246 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L HN++T + D F LT LHLDHN I + + F+ L LK LIL++N+I L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L LDLS N L+ L+PE+F ++ L+ R LR I +++ LE
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N + L + F L +L++L L+ NQL+ I F R LH L L N+
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D++ N+I L F + +LK + N L + + +L L +
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVF-ETMPNLKILLMDNNKLNSLD-SKILNSLRSL 303
Query: 352 HGVGLA 357
VGL+
Sbjct: 304 TTVGLS 309
Score = 85.4 bits (202), Expect = 5e-16
Identities = 64/209 (30%), Positives = 94/209 (44%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q A F L LH+ ++ + ++ + +F GL L+ L L+ N + + F LINL L
Sbjct: 80 QFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLD 139
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N + + E F L L+TL L +N + T+ RLF L LDLS N L L
Sbjct: 140 LSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 199
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + LR L +IN + + L L L N LT + L+KL
Sbjct: 200 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLD 259
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L GN++ I +F L +L + N+
Sbjct: 260 LTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Score = 83.8 bits (198), Expect = 1e-15
Identities = 49/156 (31%), Positives = 87/156 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ LH+ ++++ +I FW ++L L+L+ N L S+ + F GLI L ELHL+HN +
Sbjct: 159 LQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLT 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+++ F L+SL TL L N+IS L + L LDL+ N + ++ VF+ + +
Sbjct: 219 KINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPN 278
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
L+I L ++++I + + L + L NL++
Sbjct: 279 LKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
Score = 82.6 bits (195), Expect = 3e-15
Identities = 67/247 (27%), Positives = 106/247 (42%), Gaps = 1/247 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++++ + + F L L+L HN +++V D F+GL L EL L N I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ TF L +L+ L L+ NQ+S+L LF L KL L L N L + +F D + L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
LR + + + +L EL L N + F+ L L L L N++S +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
M L L L+ N + +NK++ + + SL
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNS-LRSLT 304
Query: 328 TINFSGN 334
T+ SGN
Sbjct: 305 TVGLSGN 311
Score = 66.5 bits (155), Expect = 2e-10
Identities = 68/288 (23%), Positives = 112/288 (38%), Gaps = 8/288 (2%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N +T+L + F L + + + + +L+EL L N YL
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ F L L+ L L NQLS + +F R+L L L N
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+S N++ FA ++ L+ ++ N L A L+ L +H + L +
Sbjct: 186 LDLSTNRLRSLARNGFAGLI-KLRELHLEHNQLTKINFAHFLR-LSSLHTLFLQWNKISN 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ L LDL+ N++ + L+ L + +NKL +L + L L ++
Sbjct: 244 LTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSL 303
Query: 424 AEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
V L N W C C+ ++ L +S + CHSP +G
Sbjct: 304 TTVGLSGNLWECSARICALASWLGSFQGRWEHSIL----CHSPDHTQG 347
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 117 bits (282), Expect = 1e-25
Identities = 81/246 (32%), Positives = 120/246 (48%), Gaps = 2/246 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L HN++T + D F LT LHLDHN I + + F+ L LK LIL++N+I L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L LDLS N L+ L+PE+F ++ L+ R LR I +++ LE
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N + L + F L +L++L L+ NQL+ I F R LH L L N+
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D++ N+I L F + +LK + N L + + +L L +
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVF-ETMPNLKILLMDNNKLNSLD-SKILNSLRSL 303
Query: 352 HGVGLA 357
VGL+
Sbjct: 304 TTVGLS 309
Score = 85.4 bits (202), Expect = 5e-16
Identities = 64/209 (30%), Positives = 94/209 (44%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q A F L LH+ ++ + ++ + +F GL L+ L L+ N + + F LINL L
Sbjct: 80 QFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLD 139
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N + + E F L L+TL L +N + T+ RLF L LDLS N L L
Sbjct: 140 LSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 199
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + LR L +IN + + L L L N LT + L+KL
Sbjct: 200 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLD 259
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L GN++ I +F L +L + N+
Sbjct: 260 LTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Score = 83.8 bits (198), Expect = 1e-15
Identities = 49/156 (31%), Positives = 87/156 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ LH+ ++++ +I FW ++L L+L+ N L S+ + F GLI L ELHL+HN +
Sbjct: 159 LQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLT 218
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+++ F L+SL TL L N+IS L + L LDL+ N + ++ VF+ + +
Sbjct: 219 KINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPN 278
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
L+I L ++++I + + L + L NL++
Sbjct: 279 LKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
Score = 82.6 bits (195), Expect = 3e-15
Identities = 67/247 (27%), Positives = 106/247 (42%), Gaps = 1/247 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++++ + + F L L+L HN +++V D F+GL L EL L N I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ TF L +L+ L L+ NQ+S+L LF L KL L L N L + +F D + L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
LR + + + +L EL L N + F+ L L L L N++S +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
M L L L+ N + +NK++ + + SL
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNS-LRSLT 304
Query: 328 TINFSGN 334
T+ SGN
Sbjct: 305 TVGLSGN 311
Score = 66.5 bits (155), Expect = 2e-10
Identities = 68/288 (23%), Positives = 112/288 (38%), Gaps = 8/288 (2%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N +T+L + F L + + + + +L+EL L N YL
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ F L L+ L L NQLS + +F R+L L L N
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+S N++ FA ++ L+ ++ N L A L+ L +H + L +
Sbjct: 186 LDLSTNRLRSLARNGFAGLI-KLRELHLEHNQLTKINFAHFLR-LSSLHTLFLQWNKISN 243
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ L LDL+ N++ + L+ L + +NKL +L + L L ++
Sbjct: 244 LTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSL 303
Query: 424 AEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
V L N W C C+ ++ L +S + CHSP +G
Sbjct: 304 TTVGLSGNLWECSARICALASWLGSFQGRWEHSIL----CHSPDHTQG 347
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 117 bits (282), Expect = 1e-25
Identities = 81/246 (32%), Positives = 120/246 (48%), Gaps = 2/246 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L HN++T + D F LT LHLDHN I + + F+ L LK LIL++N+I L
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L LDLS N L+ L+PE+F ++ L+ R LR I +++ LE
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N + L + F L +L++L L+ NQL+ I F R LH L L N+
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D++ N+I L F + +LK + N L + + +L L +
Sbjct: 259 CGMEWTWGTLEKLDLTGNEIKAIDLTVF-ETMPNLKILLMDNNKLNSLD-SKILNSLRSL 316
Query: 352 HGVGLA 357
VGL+
Sbjct: 317 TTVGLS 322
Score = 85.4 bits (202), Expect = 5e-16
Identities = 64/209 (30%), Positives = 94/209 (44%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q A F L LH+ ++ + ++ + +F GL L+ L L+ N + + F LINL L
Sbjct: 93 QFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLD 152
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N + + E F L L+TL L +N + T+ RLF L LDLS N L L
Sbjct: 153 LSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 212
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + LR L +IN + + L L L N LT + L+KL
Sbjct: 213 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLD 272
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L GN++ I +F L +L + N+
Sbjct: 273 LTGNEIKAIDLTVFETMPNLKILLMDNNK 301
Score = 83.8 bits (198), Expect = 1e-15
Identities = 49/156 (31%), Positives = 87/156 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ LH+ ++++ +I FW ++L L+L+ N L S+ + F GLI L ELHL+HN +
Sbjct: 172 LQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLT 231
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+++ F L+SL TL L N+IS L + L LDL+ N + ++ VF+ + +
Sbjct: 232 KINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPN 291
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
L+I L ++++I + + L + L NL++
Sbjct: 292 LKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 327
Score = 82.6 bits (195), Expect = 3e-15
Identities = 67/247 (27%), Positives = 106/247 (42%), Gaps = 1/247 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++++ + + F L L+L HN +++V D F+GL L EL L N I +
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ TF L +L+ L L+ NQ+S+L LF L KL L L N L + +F D + L
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
LR + + + +L EL L N + F+ L L L L N++S +
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
M L L L+ N + +NK++ + + SL
Sbjct: 259 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNS-LRSLT 317
Query: 328 TINFSGN 334
T+ SGN
Sbjct: 318 TVGLSGN 324
Score = 66.5 bits (155), Expect = 2e-10
Identities = 68/288 (23%), Positives = 112/288 (38%), Gaps = 8/288 (2%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N +T+L + F L + + + + +L+EL L N YL
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ F L L+ L L NQLS + +F R+L L L N
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
D+S N++ FA ++ L+ ++ N L A L+ L +H + L +
Sbjct: 199 LDLSTNRLRSLARNGFAGLI-KLRELHLEHNQLTKINFAHFLR-LSSLHTLFLQWNKISN 256
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ L LDL+ N++ + L+ L + +NKL +L + L L ++
Sbjct: 257 LTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSL 316
Query: 424 AEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
V L N W C C+ ++ L +S + CHSP +G
Sbjct: 317 TTVGLSGNLWECSARICALASWLGSFQGRWEHSIL----CHSPDHTQG 360
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 109 bits (262), Expect = 3e-23
Identities = 84/324 (25%), Positives = 139/324 (42%), Gaps = 2/324 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + N+ + + F GL +L L L+ N L + +F NL EL L NH+
Sbjct: 102 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 161
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + F HL L L L N ++ + R+F+ L L +L L +N LTD+ F +
Sbjct: 162 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 221
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ ++ + ++ ++H L+ L L N L F+ L +L +L L GN L
Sbjct: 222 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSL 281
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ +FG L L L N +S N+I F +
Sbjct: 282 KELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLT 341
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ N L + V ++L + + L N L+++P N F L+A+ L N
Sbjct: 342 E-LRELSLHTNALQ-DLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNN 399
Query: 384 KLSRFPFKLLSKTKFLQRLDISHN 407
+L P + L L + N
Sbjct: 400 QLENLPLGIFDHLGKLCELRLYDN 423
Score = 103 bits (247), Expect = 2e-21
Identities = 98/415 (23%), Positives = 167/415 (40%), Gaps = 27/415 (6%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P P+ N L I+N+++ + + F + L L + N L+ + FR L +L L L
Sbjct: 50 PLPW-NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSL 108
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+N ++ + F+ L SL++L+L++NQ+ + F + L L L N L +
Sbjct: 109 ANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGA 168
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F + L + L I+ +++ + L+ L L EN + F L L++L L
Sbjct: 169 FDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELAL 228
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
NQ+ ++ +F N L L LS N + N +
Sbjct: 229 QQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGI 288
Query: 319 FAPV------------VDSLKTINFSGNN------LPLNEIAIV----LQILPEIHGVGL 356
F P+ + SL FS L N+I+ + L E+ + L
Sbjct: 289 FGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSL 348
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
+LQ++ N F +L + L N+L + P + + L + + +N+L+ L
Sbjct: 349 HTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGI 408
Query: 417 LQRLEAIAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
L + E+ L N W CD N LL + T+ V C SP +RG
Sbjct: 409 FDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPV--CFSPANVRG 461
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 109 bits (262), Expect = 3e-23
Identities = 84/324 (25%), Positives = 139/324 (42%), Gaps = 2/324 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + N+ + + F GL +L L L+ N L + +F NL EL L NH+
Sbjct: 102 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 161
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + F HL L L L N ++ + R+F+ L L +L L +N LTD+ F +
Sbjct: 162 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 221
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ ++ + ++ ++H L+ L L N L F+ L +L +L L GN L
Sbjct: 222 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSL 281
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ +FG L L L N +S N+I F +
Sbjct: 282 KELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLT 341
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ N L + V ++L + + L N L+++P N F L+A+ L N
Sbjct: 342 E-LRELSLHTNALQ-DLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNN 399
Query: 384 KLSRFPFKLLSKTKFLQRLDISHN 407
+L P + L L + N
Sbjct: 400 QLENLPLGIFDHLGKLCELRLYDN 423
Score = 103 bits (247), Expect = 2e-21
Identities = 98/415 (23%), Positives = 167/415 (40%), Gaps = 27/415 (6%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P P+ N L I+N+++ + + F + L L + N L+ + FR L +L L L
Sbjct: 50 PLPW-NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSL 108
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+N ++ + F+ L SL++L+L++NQ+ + F + L L L N L +
Sbjct: 109 ANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGA 168
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F + L + L I+ +++ + L+ L L EN + F L L++L L
Sbjct: 169 FDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELAL 228
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
NQ+ ++ +F N L L LS N + N +
Sbjct: 229 QQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGI 288
Query: 319 FAPV------------VDSLKTINFSGNN------LPLNEIAIV----LQILPEIHGVGL 356
F P+ + SL FS L N+I+ + L E+ + L
Sbjct: 289 FGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSL 348
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
+LQ++ N F +L + L N+L + P + + L + + +N+L+ L
Sbjct: 349 HTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGI 408
Query: 417 LQRLEAIAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
L + E+ L N W CD N LL + T+ V C SP +RG
Sbjct: 409 FDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPV--CFSPANVRG 461
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 108 bits (260), Expect = 4e-23
Identities = 75/239 (31%), Positives = 116/239 (48%), Gaps = 2/239 (0%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L L+L +N+L+ + A F GL+ LT L+LDHNHI + + F+ L +K L L++N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI+ L + FR + L +DLS N L L P++F ++ L R ++ + +I+
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ LD+G N K L + F L +L +L L+ N L + F R LH L L RN
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
+ D+S N+I+ F V L+++ N L E I+
Sbjct: 244 K-VAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF-ETVPHLQSLQLDSNRLTYIEPRIL 300
Score = 87.8 bits (208), Expect = 9e-17
Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 1/201 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
++EL + ++ + + +F + NLR ++L++N L ++ D F GL LT LH+ N I+
Sbjct: 115 VKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ SLK L + NQ+ +L F L KL+ L L N L +N F +
Sbjct: 175 FVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLIS 234
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L RR + + + + V LE++DL N +Y+ F ++ L+ L+LD N+L+
Sbjct: 235 LHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLT 293
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I + + L +TL+ N
Sbjct: 294 YIEPRILNSWKSLTSITLAGN 314
Score = 65.3 bits (152), Expect = 5e-10
Identities = 50/204 (24%), Positives = 92/204 (45%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ L L++ ++++ S+ +F L+ ++ L L+ N +T + FR + NL + L +N
Sbjct: 89 MQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNK 148
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ ++ + F L L TL + N I + R+F+ L LD+ N L L F +
Sbjct: 149 LQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGL 208
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L L ++N + + L L L N + S + L+K+ L GN+
Sbjct: 209 FKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNE 267
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
+ + ++F L L L NR
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNR 291
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 25/183 (13%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQN------------------------LRVLNLTH 116
P NLR + + + + ++ F GL+ L+ L++ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFR 176
N L S+ ++F GL LTELHL+HN + +++ F L SL +L L N+++ +VS L
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-D 253
Query: 177 MLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
+ L +DLS N + + P VF+ + HL+ + L I +I + L + L
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Query: 237 NLF 239
NL+
Sbjct: 314 NLW 316
Score = 62.5 bits (145), Expect = 4e-09
Identities = 59/263 (22%), Positives = 112/263 (42%), Gaps = 9/263 (3%)
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E +L+ L L L N +S L + F L +L+ L L N + + + F+ ++ ++
Sbjct: 58 TEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKE 117
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ + +P L +DL N + L D F L++L L + N + +
Sbjct: 118 LTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+F R L L + N+ + HN + + + F P + SL
Sbjct: 178 VRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHF-PRLISLH 236
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI---PQNFFTYNEHLVALDLSWNK 384
++ L N++AIV+ L + + +LS EI + F HL +L L N+
Sbjct: 237 SL-----CLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNR 291
Query: 385 LSRFPFKLLSKTKFLQRLDISHN 407
L+ ++L+ K L + ++ N
Sbjct: 292 LTYIEPRILNSWKSLTSITLAGN 314
Score = 38.7 bits (86), Expect = 0.054
Identities = 21/85 (24%), Positives = 41/85 (48%)
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+P + V L+ LQ + + F L L + N + P ++ + L+ LDI +N
Sbjct: 136 MPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYN 195
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN 432
+L++L+ L + E++L N+
Sbjct: 196 QLKSLARNSFAGLFKLTELHLEHND 220
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 108 bits (260), Expect = 4e-23
Identities = 75/239 (31%), Positives = 116/239 (48%), Gaps = 2/239 (0%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L L+L +N+L+ + A F GL+ LT L+LDHNHI + + F+ L +K L L++N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI+ L + FR + L +DLS N L L P++F ++ L R ++ + +I+
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ LD+G N K L + F L +L +L L+ N L + F R LH L L RN
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
+ D+S N+I+ F V L+++ N L E I+
Sbjct: 244 K-VAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF-ETVPHLQSLQLDSNRLTYIEPRIL 300
Score = 87.8 bits (208), Expect = 9e-17
Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 1/201 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
++EL + ++ + + +F + NLR ++L++N L ++ D F GL LT LH+ N I+
Sbjct: 115 VKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ SLK L + NQ+ +L F L KL+ L L N L +N F +
Sbjct: 175 FVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLIS 234
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L RR + + + + V LE++DL N +Y+ F ++ L+ L+LD N+L+
Sbjct: 235 LHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLT 293
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I + + L +TL+ N
Sbjct: 294 YIEPRILNSWKSLTSITLAGN 314
Score = 65.3 bits (152), Expect = 5e-10
Identities = 50/204 (24%), Positives = 92/204 (45%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ L L++ ++++ S+ +F L+ ++ L L+ N +T + FR + NL + L +N
Sbjct: 89 MQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNK 148
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ ++ + F L L TL + N I + R+F+ L LD+ N L L F +
Sbjct: 149 LQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGL 208
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L L ++N + + L L L N + S + L+K+ L GN+
Sbjct: 209 FKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNE 267
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
+ + ++F L L L NR
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNR 291
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 25/183 (13%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQN------------------------LRVLNLTH 116
P NLR + + + + ++ F GL+ L+ L++ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFR 176
N L S+ ++F GL LTELHL+HN + +++ F L SL +L L N+++ +VS L
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-D 253
Query: 177 MLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
+ L +DLS N + + P VF+ + HL+ + L I +I + L + L
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Query: 237 NLF 239
NL+
Sbjct: 314 NLW 316
Score = 62.5 bits (145), Expect = 4e-09
Identities = 59/263 (22%), Positives = 112/263 (42%), Gaps = 9/263 (3%)
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E +L+ L L L N +S L + F L +L+ L L N + + + F+ ++ ++
Sbjct: 58 TEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKE 117
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ + +P L +DL N + L D F L++L L + N + +
Sbjct: 118 LTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+F R L L + N+ + HN + + + F P + SL
Sbjct: 178 VRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHF-PRLISLH 236
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI---PQNFFTYNEHLVALDLSWNK 384
++ L N++AIV+ L + + +LS EI + F HL +L L N+
Sbjct: 237 SL-----CLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNR 291
Query: 385 LSRFPFKLLSKTKFLQRLDISHN 407
L+ ++L+ K L + ++ N
Sbjct: 292 LTYIEPRILNSWKSLTSITLAGN 314
Score = 38.7 bits (86), Expect = 0.054
Identities = 21/85 (24%), Positives = 41/85 (48%)
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+P + V L+ LQ + + F L L + N + P ++ + L+ LDI +N
Sbjct: 136 MPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYN 195
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN 432
+L++L+ L + E++L N+
Sbjct: 196 QLKSLARNSFAGLFKLTELHLEHND 220
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 108 bits (260), Expect = 4e-23
Identities = 75/239 (31%), Positives = 116/239 (48%), Gaps = 2/239 (0%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L L+L +N+L+ + A F GL+ LT L+LDHNHI + + F+ L +K L L++N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI+ L + FR + L +DLS N L L P++F ++ L R ++ + +I+
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ LD+G N K L + F L +L +L L+ N L + F R LH L L RN
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
+ D+S N+I+ F V L+++ N L E I+
Sbjct: 244 K-VAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF-ETVPHLQSLQLDSNRLTYIEPRIL 300
Score = 87.8 bits (208), Expect = 9e-17
Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 1/201 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
++EL + ++ + + +F + NLR ++L++N L ++ D F GL LT LH+ N I+
Sbjct: 115 VKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ SLK L + NQ+ +L F L KL+ L L N L +N F +
Sbjct: 175 FVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLIS 234
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L RR + + + + V LE++DL N +Y+ F ++ L+ L+LD N+L+
Sbjct: 235 LHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLT 293
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I + + L +TL+ N
Sbjct: 294 YIEPRILNSWKSLTSITLAGN 314
Score = 65.3 bits (152), Expect = 5e-10
Identities = 50/204 (24%), Positives = 92/204 (45%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ L L++ ++++ S+ +F L+ ++ L L+ N +T + FR + NL + L +N
Sbjct: 89 MQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNK 148
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ ++ + F L L TL + N I + R+F+ L LD+ N L L F +
Sbjct: 149 LQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGL 208
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L L ++N + + L L L N + S + L+K+ L GN+
Sbjct: 209 FKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNE 267
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
+ + ++F L L L NR
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNR 291
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 25/183 (13%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQN------------------------LRVLNLTH 116
P NLR + + + + ++ F GL+ L+ L++ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFR 176
N L S+ ++F GL LTELHL+HN + +++ F L SL +L L N+++ +VS L
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-D 253
Query: 177 MLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
+ L +DLS N + + P VF+ + HL+ + L I +I + L + L
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Query: 237 NLF 239
NL+
Sbjct: 314 NLW 316
Score = 62.5 bits (145), Expect = 4e-09
Identities = 59/263 (22%), Positives = 112/263 (42%), Gaps = 9/263 (3%)
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E +L+ L L L N +S L + F L +L+ L L N + + + F+ ++ ++
Sbjct: 58 TEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKE 117
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ + +P L +DL N + L D F L++L L + N + +
Sbjct: 118 LTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+F R L L + N+ + HN + + + F P + SL
Sbjct: 178 VRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHF-PRLISLH 236
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI---PQNFFTYNEHLVALDLSWNK 384
++ L N++AIV+ L + + +LS EI + F HL +L L N+
Sbjct: 237 SL-----CLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNR 291
Query: 385 LSRFPFKLLSKTKFLQRLDISHN 407
L+ ++L+ K L + ++ N
Sbjct: 292 LTYIEPRILNSWKSLTSITLAGN 314
Score = 38.7 bits (86), Expect = 0.054
Identities = 21/85 (24%), Positives = 41/85 (48%)
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+P + V L+ LQ + + F L L + N + P ++ + L+ LDI +N
Sbjct: 136 MPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYN 195
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN 432
+L++L+ L + E++L N+
Sbjct: 196 QLKSLARNSFAGLFKLTELHLEHND 220
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 108 bits (260), Expect = 4e-23
Identities = 75/239 (31%), Positives = 116/239 (48%), Gaps = 2/239 (0%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L L+L +N+L+ + A F GL+ LT L+LDHNHI + + F+ L +K L L++N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI+ L + FR + L +DLS N L L P++F ++ L R ++ + +I+
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ LD+G N K L + F L +L +L L+ N L + F R LH L L RN
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
+ D+S N+I+ F V L+++ N L E I+
Sbjct: 244 K-VAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF-ETVPHLQSLQLDSNRLTYIEPRIL 300
Score = 87.8 bits (208), Expect = 9e-17
Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 1/201 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
++EL + ++ + + +F + NLR ++L++N L ++ D F GL LT LH+ N I+
Sbjct: 115 VKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQ 174
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ SLK L + NQ+ +L F L KL+ L L N L +N F +
Sbjct: 175 FVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLIS 234
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L RR + + + + V LE++DL N +Y+ F ++ L+ L+LD N+L+
Sbjct: 235 LHSLCLRRNKVAIVVSSL-DWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLT 293
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I + + L +TL+ N
Sbjct: 294 YIEPRILNSWKSLTSITLAGN 314
Score = 65.3 bits (152), Expect = 5e-10
Identities = 50/204 (24%), Positives = 92/204 (45%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ L L++ ++++ S+ +F L+ ++ L L+ N +T + FR + NL + L +N
Sbjct: 89 MQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNK 148
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ ++ + F L L TL + N I + R+F+ L LD+ N L L F +
Sbjct: 149 LQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGL 208
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L L ++N + + L L L N + S + L+K+ L GN+
Sbjct: 209 FKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNE 267
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
+ + ++F L L L NR
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNR 291
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 25/183 (13%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQN------------------------LRVLNLTH 116
P NLR + + + + ++ F GL+ L+ L++ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFR 176
N L S+ ++F GL LTELHL+HN + +++ F L SL +L L N+++ +VS L
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL-D 253
Query: 177 MLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
+ L +DLS N + + P VF+ + HL+ + L I +I + L + L
Sbjct: 254 WVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Query: 237 NLF 239
NL+
Sbjct: 314 NLW 316
Score = 62.5 bits (145), Expect = 4e-09
Identities = 59/263 (22%), Positives = 112/263 (42%), Gaps = 9/263 (3%)
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E +L+ L L L N +S L + F L +L+ L L N + + + F+ ++ ++
Sbjct: 58 TEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKE 117
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ + +P L +DL N + L D F L++L L + N + +
Sbjct: 118 LTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+F R L L + N+ + HN + + + F P + SL
Sbjct: 178 VRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHF-PRLISLH 236
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI---PQNFFTYNEHLVALDLSWNK 384
++ L N++AIV+ L + + +LS EI + F HL +L L N+
Sbjct: 237 SL-----CLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNR 291
Query: 385 LSRFPFKLLSKTKFLQRLDISHN 407
L+ ++L+ K L + ++ N
Sbjct: 292 LTYIEPRILNSWKSLTSITLAGN 314
Score = 38.7 bits (86), Expect = 0.054
Identities = 21/85 (24%), Positives = 41/85 (48%)
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+P + V L+ LQ + + F L L + N + P ++ + L+ LDI +N
Sbjct: 136 MPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYN 195
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN 432
+L++L+ L + E++L N+
Sbjct: 196 QLKSLARNSFAGLFKLTELHLEHND 220
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 107 bits (258), Expect = 8e-23
Identities = 84/324 (25%), Positives = 139/324 (42%), Gaps = 2/324 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + N+ + + F GL +L L L+ N L + +F NL EL L NH+
Sbjct: 102 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 161
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + F HL L L L N ++ + R+F+ L L +L L +N LTD+ F +
Sbjct: 162 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 221
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ ++ + ++ ++H L+ L L N L F+ L +L +L L GN L
Sbjct: 222 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSL 281
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ +FG L L L N +S N+I F +
Sbjct: 282 KELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLT 341
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+ L+ ++ N L + V ++L + + L N L+++P N F L+A+ L N
Sbjct: 342 E-LRELSLHTNALQ-DLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNN 399
Query: 384 KLSRFPFKLLSKTKFLQRLDISHN 407
+L P + L L + N
Sbjct: 400 QLENLPLGIFDHLGKLCELRLYDN 423
Score = 106 bits (254), Expect = 2e-22
Identities = 99/415 (23%), Positives = 168/415 (40%), Gaps = 27/415 (6%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P P+ N L I+N+++ + + F + L L + N L+ + FR L +L L L
Sbjct: 50 PLPW-NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSL 108
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+N ++ + F+ L SL++L+L++NQ+ + F + L L L N L +
Sbjct: 109 ANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGA 168
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F + L + L I+ +++ + L+ L L EN + F L L++L L
Sbjct: 169 FDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELAL 228
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
NQ+ ++ +F N L L LS N + N + L
Sbjct: 229 QQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGI 288
Query: 319 FAPV------------VDSLKTINFSGNN------LPLNEIAIV----LQILPEIHGVGL 356
F P+ + SL FS L N+I+ + L E+ + L
Sbjct: 289 FGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSL 348
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
+LQ++ N F +L + L N+L + P + + L + + +N+L+ L
Sbjct: 349 HTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGI 408
Query: 417 LQRLEAIAEVNLMKNNWHCDQ--CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
L + E+ L N W CD N LL + T+ V C SP +RG
Sbjct: 409 FDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPV--CFSPANVRG 461
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 289
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 309
Query: 333 GN 334
GN
Sbjct: 310 GN 311
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 171 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 231 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 290
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 291 NISQETVNAWISLISITLSGN 311
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 90 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 150 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 210 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 270 PGTFKCLPNLQKLNLDSNK 288
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 239
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 240 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 279
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 280 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 337
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 338 ICAGPKHIQG 347
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 149 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 209 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 268
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 269 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 314
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 261 N 261
N
Sbjct: 311 N 311
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 289
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 309
Query: 333 GN 334
GN
Sbjct: 310 GN 311
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 171 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 231 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 290
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 291 NISQETVNAWISLISITLSGN 311
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 90 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 150 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 210 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 270 PGTFKCLPNLQKLNLDSNK 288
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 239
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 240 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 279
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 280 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 337
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 338 ICAGPKHIQG 347
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 149 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 209 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 268
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 269 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 314
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 261 N 261
N
Sbjct: 311 N 311
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 290
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 310
Query: 333 GN 334
GN
Sbjct: 311 GN 312
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 112 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 171
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 172 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 231
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 232 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 291
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 292 NISQETVNAWISLISITLSGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 91 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 150
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 151 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 210
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 211 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 270
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 271 PGTFKCLPNLQKLNLDSNK 289
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 240
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 241 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 280
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 281 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 338
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 339 ICAGPKHIQG 348
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 150 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 209
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 210 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 269
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 270 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 315
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Query: 261 N 261
N
Sbjct: 312 N 312
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 290
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 310
Query: 333 GN 334
GN
Sbjct: 311 GN 312
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 112 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 171
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 172 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 231
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 232 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 291
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 292 NISQETVNAWISLISITLSGN 312
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 91 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 150
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 151 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 210
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 211 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 270
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 271 PGTFKCLPNLQKLNLDSNK 289
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 240
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 241 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 280
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 281 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 338
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 339 ICAGPKHIQG 348
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 150 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 209
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 210 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 269
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 270 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 315
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Query: 261 N 261
N
Sbjct: 312 N 312
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 289
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 309
Query: 333 GN 334
GN
Sbjct: 310 GN 311
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 171 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 231 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 290
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 291 NISQETVNAWISLISITLSGN 311
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 90 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 150 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 210 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 270 PGTFKCLPNLQKLNLDSNK 288
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 239
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 240 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 279
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 280 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 337
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 338 ICAGPKHIQG 347
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 149 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 209 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 268
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 269 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 314
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 261 N 261
N
Sbjct: 311 N 311
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 289
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 309
Query: 333 GN 334
GN
Sbjct: 310 GN 311
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 171 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 231 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 290
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 291 NISQETVNAWISLISITLSGN 311
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 90 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 150 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 210 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 270 PGTFKCLPNLQKLNLDSNK 288
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 239
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 240 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 279
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 280 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 337
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 338 ICAGPKHIQG 347
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 149 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 209 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 268
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 269 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 314
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 261 N 261
N
Sbjct: 311 N 311
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 107 bits (256), Expect = 1e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 1/225 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L N++ + ++ F GL L L+LDHN+I + + F+ + LK LIL++N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
++ F + L LDLS N L L E FK ++ L I R L+ + +++ L+
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDLG N + L+ + F L +LK+L L+ NQ S I F R L + L NR
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D+S N I TF + +L+ +N N L
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQGIEPGTF-KCLPNLQKLNLDSNKL 289
Score = 91.9 bits (218), Expect = 5e-18
Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+++ + F GL L L L HN ++SV D F+G+ L EL L N I + ++TF
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
+ +L+ L L+ N++ TL S F+ L KL IL L N L + VF+D ++L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
LR ++ + + +L+EL L N F + F L L+ + L N++ I +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
LH L LS N ++ NK+ +T + SL +I S
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWI-SLISITLS 309
Query: 333 GN 334
GN
Sbjct: 310 GN 311
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/201 (28%), Positives = 96/201 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + ++ + + +F + NLR L+L++N L ++ ++ F+GL L LHL N ++
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLK 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ +L L L N++ +L F L KL L L N + +N F + +
Sbjct: 171 TVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFN 230
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
LR + +R I+ + L LDL N + + F L L+KL LD N+L+
Sbjct: 231 LRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLT 290
Query: 265 VIVDNMFGRNRELHVLTLSRN 285
I L +TLS N
Sbjct: 291 NISQETVNAWISLISITLSGN 311
Score = 71.7 bits (168), Expect = 6e-12
Identities = 51/199 (25%), Positives = 89/199 (44%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ ++ + S+ + +F G++ L+ L L+ N +T + F + NL L L +N ++ +
Sbjct: 90 LYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQ 149
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE F+ L L L L +N + T+ R+F+ L LDL N L L+ F + L+
Sbjct: 150 SEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKE 209
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+IN + + L + L N + ++ + L L L GN + I
Sbjct: 210 LHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE 269
Query: 268 DNMFGRNRELHVLTLSRNR 286
F L L L N+
Sbjct: 270 PGTFKCLPNLQKLNLDSNK 288
Score = 68.9 bits (161), Expect = 4e-11
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 28/310 (9%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I L S F L +L L L N ++ ++ + F+ I+ L+ + ++
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
+ +H VP L LDL N + L S++F L++L L L N L + +F R L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
L L NR + HN+ + + F P + +L++I L N
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHF-PRLFNLRSIY-----LQWN 239
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
I + Q GL +T++ L LDLS N + L
Sbjct: 240 RIRSISQ--------GLT-----------WTWSS-LHNLDLSGNDIQGIEPGTFKCLPNL 279
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
Q+L++ NKL +S++ + ++ + L N W C + L Y + +
Sbjct: 280 QKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICP--LFYWLKNFKGNKESTM 337
Query: 460 KCHSPLRLRG 469
C P ++G
Sbjct: 338 ICAGPKHIQG 347
Score = 68.1 bits (159), Expect = 8e-11
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 3/166 (1%)
Query: 78 QPAPFVNLREL---HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
Q F LR+L H+ ++++ ++ F +NL L+L +N L S+ + F GL+ L
Sbjct: 149 QSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
ELHL+HN +++ F L +L+++ L N+I ++ L + L LDLS N + +
Sbjct: 209 ELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGI 268
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
P FK + +L+ L I+ + + L + L N+++
Sbjct: 269 EPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWE 314
Score = 58.4 bits (135), Expect = 6e-08
Identities = 46/181 (25%), Positives = 79/181 (43%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NLR L + + + ++ F GL+ L +L+L N+L +V F+ NL L L +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + +S F L LK L L +NQ S + F L L + L N + ++ +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
L ++ I + +P L++L+L N ++ + + L + L G
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 261 N 261
N
Sbjct: 311 N 311
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 106 bits (254), Expect = 2e-22
Identities = 104/406 (25%), Positives = 164/406 (40%), Gaps = 10/406 (2%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
+ + V ++ ++ +F NL + + L D F GL L +L + +
Sbjct: 52 KNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLN 111
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+S+ F +LTSL L L N + L LF+ LA L L L N L L +F+ + HL
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
+ + LL ++ +++H + L+ L L N L F L L++L LD N +S
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
+ +F + L L L RN + N + FA
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHT-PC 290
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L ++ + N L L + + L+ ++ +P F E LV L L N L
Sbjct: 291 LVGLSLTHNQLETVAEGTFAH-LSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS---N 442
+ L L+ L +S N+L TL E + + L N W CD C + N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCD-CHLAYLFN 408
Query: 443 MLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
L T +LN I+ C P L+G +L+ +QL CP T +
Sbjct: 409 WLQQYTDRLLN--IQTY-CAGPAYLKGQVVPALNEKQL-VCPVTRD 450
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 106 bits (254), Expect = 2e-22
Identities = 104/406 (25%), Positives = 164/406 (40%), Gaps = 10/406 (2%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
+ + V ++ ++ +F NL + + L D F GL L +L + +
Sbjct: 52 KNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLN 111
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+S+ F +LTSL L L N + L LF+ LA L L L N L L +F+ + HL
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
+ + LL ++ +++H + L+ L L N L F L L++L LD N +S
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
+ +F + L L L RN + N + FA
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHT-PC 290
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L ++ + N L L + + L+ ++ +P F E LV L L N L
Sbjct: 291 LVGLSLTHNQLETVAEGTFAH-LSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS---N 442
+ L L+ L +S N+L TL E + + L N W CD C + N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCD-CHLAYLFN 408
Query: 443 MLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
L T +LN I+ C P L+G +L+ +QL CP T +
Sbjct: 409 WLQQYTDRLLN--IQTY-CAGPAYLKGQVVPALNEKQL-VCPVTRD 450
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 105 bits (253), Expect = 3e-22
Identities = 104/406 (25%), Positives = 164/406 (40%), Gaps = 10/406 (2%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
+ + V ++ ++ +F NL + + L D F GL L +L + +
Sbjct: 52 KNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLN 111
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+S+ F +LTSL L L N + L LF+ LA L L L N L L +F+ + HL
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHL 171
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
+ + LL ++ +++H + L+ L L N L F L L++L LD N +S
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
+ +F + L L L RN + N + FA
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHT-PC 290
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L ++ + N L L + + L+ ++ +P F E LV L L N L
Sbjct: 291 LVGLSLTHNQLETVAEGTFAH-LSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS---N 442
+ L L+ L +S N+L TL E + + L N W CD C + N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCD-CHLAYLFN 408
Query: 443 MLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
L T +LN I+ C P L+G +L+ +QL CP T +
Sbjct: 409 WLQQYTDRLLN--IQTY-CAGPAYLKGQVVPALNEKQL-VCPVTRD 450
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 103 bits (247), Expect = 2e-21
Identities = 90/356 (25%), Positives = 147/356 (41%), Gaps = 9/356 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L I +S++ ++ +F L L+ L L+ N +T + ++ L +L LDHN +
Sbjct: 76 LQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALR 135
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ L +L+ L L NQ+ L + LF L L +LDLS N LT L +
Sbjct: 136 GIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAK 195
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L +++ + + + L EL N + + F L L L L N L+
Sbjct: 196 LERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLA 255
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF-APVV 323
+ +F + L +LTL N + ++R L+T A
Sbjct: 256 FLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGG-----LQELWLNRTQLRTLPAAAF 310
Query: 324 DSLKTINFSGNNLPLNEIAI---VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDL 380
+L + + G L A+ Q L E+ + L + L +P L + L
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 381 SWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCD 436
N+L P L L+ + + HN+L+TL L + EV L N+W CD
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCD 426
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 118/279 (42%), Gaps = 5/279 (1%)
Query: 35 QVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSN 94
Q+ H +R I + + V++ +A ++ +FL +FT NL+ L + +N
Sbjct: 126 QLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPAS-LFTN---LENLKLLDLSGNN 181
Query: 95 VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL 154
+ + + L L L N L S+ + L LTEL NHI ++ F L
Sbjct: 182 LTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRL 241
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
+L +L L+ N ++ L S LF L++L L +NPL +L +F ++ L+ R
Sbjct: 242 PNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQ 301
Query: 215 LRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
LR + + + RL L + L F L L+ L L N L+ + D +
Sbjct: 302 LRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRG 361
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
+L ++L RNR + HN+++
Sbjct: 362 LGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/270 (22%), Positives = 111/270 (41%), Gaps = 4/270 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T+L ++L L S+ F + L L +SD+ ++ + P F D+ L+ + R
Sbjct: 50 TNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNK 109
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
+ + + + LE+L L N + + + F L L++L L+ NQL + ++F
Sbjct: 110 ITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNL 169
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L +L LS N + N++ + +L + F N
Sbjct: 170 ENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLD-SGLLNSLGALTELQFHRN 228
Query: 335 NLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ + IA LP + + L+ L +P F ++ +L L L N L+ P L
Sbjct: 229 H--IRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ LQ L ++ +L+TL + L +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Score = 60.9 bits (141), Expect = 1e-08
Identities = 73/313 (23%), Positives = 127/313 (40%), Gaps = 11/313 (3%)
Query: 124 ADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSI 183
+ +F G+ L L + +HI ++ TF L LKTL L+ N+I+ L L + L
Sbjct: 67 SQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQ 126
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L ++ +F+ + +L+ + L + ++ + L+ LDL N +L
Sbjct: 127 LFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLP 186
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ +L++L L N+L + + L L RN
Sbjct: 187 KGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSS 246
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL---PLNEI-AIVLQILPEIHGVGLANL 359
+S N HL F P L + N + L PL E+ ++ + + + L
Sbjct: 247 LTLSRN-----HL-AFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRT 300
Query: 360 SLQEIPQNFFTYNEHLVALDLSWN-KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+ +P F L L ++ + +LS P LQ L + N L L + L+
Sbjct: 301 QLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLR 360
Query: 419 RLEAIAEVNLMKN 431
L + +V+L +N
Sbjct: 361 GLGKLRQVSLRRN 373
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 103 bits (247), Expect = 2e-21
Identities = 90/356 (25%), Positives = 147/356 (41%), Gaps = 9/356 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L I +S++ ++ +F L L+ L L+ N +T + ++ L +L LDHN +
Sbjct: 76 LQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALR 135
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F+ L +L+ L L NQ+ L + LF L L +LDLS N LT L +
Sbjct: 136 GIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAK 195
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L +++ + + + L EL N + + F L L L L N L+
Sbjct: 196 LERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLA 255
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF-APVV 323
+ +F + L +LTL N + ++R L+T A
Sbjct: 256 FLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGG-----LQELWLNRTQLRTLPAAAF 310
Query: 324 DSLKTINFSGNNLPLNEIAI---VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDL 380
+L + + G L A+ Q L E+ + L + L +P L + L
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 381 SWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCD 436
N+L P L L+ + + HN+L+TL L + EV L N+W CD
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCD 426
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 118/279 (42%), Gaps = 5/279 (1%)
Query: 35 QVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSN 94
Q+ H +R I + + V++ +A ++ +FL +FT NL+ L + +N
Sbjct: 126 QLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPAS-LFTN---LENLKLLDLSGNN 181
Query: 95 VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL 154
+ + + L L L N L S+ + L LTEL NHI ++ F L
Sbjct: 182 LTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRL 241
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
+L +L L+ N ++ L S LF L++L L +NPL +L +F ++ L+ R
Sbjct: 242 PNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQ 301
Query: 215 LRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
LR + + + RL L + L F L L+ L L N L+ + D +
Sbjct: 302 LRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRG 361
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
+L ++L RNR + HN+++
Sbjct: 362 LGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/270 (22%), Positives = 111/270 (41%), Gaps = 4/270 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T+L ++L L S+ F + L L +SD+ ++ + P F D+ L+ + R
Sbjct: 50 TNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNK 109
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
+ + + + LE+L L N + + + F L L++L L+ NQL + ++F
Sbjct: 110 ITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNL 169
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L +L LS N + N++ + +L + F N
Sbjct: 170 ENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLD-SGLLNSLGALTELQFHRN 228
Query: 335 NLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ + IA LP + + L+ L +P F ++ +L L L N L+ P L
Sbjct: 229 H--IRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+ LQ L ++ +L+TL + L +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Score = 60.9 bits (141), Expect = 1e-08
Identities = 73/313 (23%), Positives = 127/313 (40%), Gaps = 11/313 (3%)
Query: 124 ADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSI 183
+ +F G+ L L + +HI ++ TF L LKTL L+ N+I+ L L + L
Sbjct: 67 SQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQ 126
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L N L ++ +F+ + +L+ + L + ++ + L+ LDL N +L
Sbjct: 127 LFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLP 186
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
+ +L++L L N+L + + L L RN
Sbjct: 187 KGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSS 246
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL---PLNEI-AIVLQILPEIHGVGLANL 359
+S N HL F P L + N + L PL E+ ++ + + + L
Sbjct: 247 LTLSRN-----HL-AFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRT 300
Query: 360 SLQEIPQNFFTYNEHLVALDLSWN-KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+ +P F L L ++ + +LS P LQ L + N L L + L+
Sbjct: 301 QLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLR 360
Query: 419 RLEAIAEVNLMKN 431
L + +V+L +N
Sbjct: 361 GLGKLRQVSLRRN 373
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 102 bits (245), Expect = 3e-21
Identities = 65/204 (31%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NLR L++ + V + + F L +++ LNL N LT + + F G++ L L L +N+
Sbjct: 132 LNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNN 191
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I ++S F+HL +L L L +N ++ + S F +L L L LS NP+ + P FK +
Sbjct: 192 ILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGL 251
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + +R + + + L+ L L N + L SD F LK L LKLD N+
Sbjct: 252 ANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
Query: 263 -LSVIVDNMFGRNRELHVLTLSRN 285
+S+ D L +L LS N
Sbjct: 312 IISIDNDTFENMGASLKILNLSFN 335
Score = 88.2 bits (209), Expect = 7e-17
Identities = 65/253 (25%), Positives = 114/253 (45%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L++ NSN+ + +F L++L L L +N + + F+GL+NL L+L +N +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L S++ L L N+++ L S F + L ILDLS+N + ++ F+ ++
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L ++ + + ++ L L L N + + F L L+ L L +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L LS N + N+I TF +
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMG 324
Query: 324 DSLKTINFSGNNL 336
SLK +N S NNL
Sbjct: 325 ASLKILNLSFNNL 337
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/233 (27%), Positives = 102/233 (43%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N+ I + GL +L L L ++N+ V F L +L L L++N I+++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
F+ L +L+ L L NQ+S + +F L + L+L N LT L F + LRI
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ RI+ + + L L LG N + S+ F LK L++L L N + I
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
F L L L +R +SHN ++ + TF+
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Score = 67.3 bits (157), Expect = 1e-10
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 1/108 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L + NS + ++ + F G+ NL+ L L+HN+L ++ +D F L NL L LD N I
Sbjct: 253 NLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
Query: 144 EQMSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ ++TF ++ SLK L L+ N ++ L R+ + L+ L L + NP
Sbjct: 313 ISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNP 360
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 102 bits (245), Expect = 3e-21
Identities = 65/204 (31%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NLR L++ + V + + F L +++ LNL N LT + + F G++ L L L +N+
Sbjct: 132 LNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNN 191
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I ++S F+HL +L L L +N ++ + S F +L L L LS NP+ + P FK +
Sbjct: 192 ILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGL 251
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + +R + + + L+ L L N + L SD F LK L LKLD N+
Sbjct: 252 ANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
Query: 263 -LSVIVDNMFGRNRELHVLTLSRN 285
+S+ D L +L LS N
Sbjct: 312 IISIDNDTFENMGASLKILNLSFN 335
Score = 88.2 bits (209), Expect = 7e-17
Identities = 65/253 (25%), Positives = 114/253 (45%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L++ NSN+ + +F L++L L L +N + + F+GL+NL L+L +N +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L S++ L L N+++ L S F + L ILDLS+N + ++ F+ ++
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L ++ + + ++ L L L N + + F L L+ L L +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L LS N + N+I TF +
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMG 324
Query: 324 DSLKTINFSGNNL 336
SLK +N S NNL
Sbjct: 325 ASLKILNLSFNNL 337
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/233 (27%), Positives = 102/233 (43%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N+ I + GL +L L L ++N+ V F L +L L L++N I+++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
F+ L +L+ L L NQ+S + +F L + L+L N LT L F + LRI
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ RI+ + + L L LG N + S+ F LK L++L L N + I
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
F L L L +R +SHN ++ + TF+
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Score = 67.3 bits (157), Expect = 1e-10
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 1/108 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L + NS + ++ + F G+ NL+ L L+HN+L ++ +D F L NL L LD N I
Sbjct: 253 NLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
Query: 144 EQMSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ ++TF ++ SLK L L+ N ++ L R+ + L+ L L + NP
Sbjct: 313 ISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNP 360
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 102 bits (245), Expect = 3e-21
Identities = 65/204 (31%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NLR L++ + V + + F L +++ LNL N LT + + F G++ L L L +N+
Sbjct: 132 LNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNN 191
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I ++S F+HL +L L L +N ++ + S F +L L L LS NP+ + P FK +
Sbjct: 192 ILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGL 251
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + +R + + + L+ L L N + L SD F LK L LKLD N+
Sbjct: 252 ANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
Query: 263 -LSVIVDNMFGRNRELHVLTLSRN 285
+S+ D L +L LS N
Sbjct: 312 IISIDNDTFENMGASLKILNLSFN 335
Score = 88.2 bits (209), Expect = 7e-17
Identities = 65/253 (25%), Positives = 114/253 (45%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L++ NSN+ + +F L++L L L +N + + F+GL+NL L+L +N +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L S++ L L N+++ L S F + L ILDLS+N + ++ F+ ++
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L ++ + + ++ L L L N + + F L L+ L L +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F L L LS N + N+I TF +
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMG 324
Query: 324 DSLKTINFSGNNL 336
SLK +N S NNL
Sbjct: 325 ASLKILNLSFNNL 337
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/233 (27%), Positives = 102/233 (43%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N+ I + GL +L L L ++N+ V F L +L L L++N I+++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
F+ L +L+ L L NQ+S + +F L + L+L N LT L F + LRI
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ RI+ + + L L LG N + S+ F LK L++L L N + I
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
F L L L +R +SHN ++ + TF+
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Score = 67.3 bits (157), Expect = 1e-10
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 1/108 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L + NS + ++ + F G+ NL+ L L+HN+L ++ +D F L NL L LD N I
Sbjct: 253 NLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
Query: 144 EQMSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ ++TF ++ SLK L L+ N ++ L R+ + L+ L L + NP
Sbjct: 313 ISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNP 360
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 98.7 bits (235), Expect = 5e-20
Identities = 76/264 (28%), Positives = 125/264 (47%), Gaps = 7/264 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 151 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 210
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 211 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 270
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + R+ + +N + + +L+ELDLG N + L F LK L +L L N
Sbjct: 271 SNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNP 330
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+ I N F +L L+L ++SH +F +AP
Sbjct: 331 IQKIQANQFDYLVKLKSLSLE-----GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPH 385
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQ 346
V S K N G + N +A ++Q
Sbjct: 386 VRSCKP-NTDGISSLENLLASIIQ 408
Score = 81.4 bits (192), Expect = 8e-15
Identities = 61/227 (26%), Positives = 107/227 (47%), Gaps = 2/227 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L L L N+
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
++S+N I + F +V LK+++ G
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLV-KLKSLSLEG 352
Score = 61.7 bits (143), Expect = 7e-09
Identities = 66/256 (25%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N+T + L N I ++ + F++ L+ L L NN+I+++ FR L L+ L LS N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
T L P VF+D+ RLE L + +N ++ F L
Sbjct: 187 TFLKPGVFEDLH------------------------RLEWLIIEDNHLSRISPPTFYGLN 222
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNR-ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
L L L N L+ + D ++ LH L L N + NK
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
I+ + TFAP+ L ++ N + N ++ + L E+ + L+ +Q+I N F
Sbjct: 283 INHLNENTFAPL-QKLDELDLGSNKIE-NLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 371 YNEHLVALDLSWNKLS 386
Y L +L L ++S
Sbjct: 341 YLVKLKSLSLEGIEIS 356
Score = 48.0 bits (109), Expect = 9e-05
Identities = 47/200 (23%), Positives = 79/200 (39%), Gaps = 1/200 (0%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L NL + L D F + L+KL L N+++ I F L L LS NR
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
I N + R TF + +SL + N L + Q +P +
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRL 249
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H + L + + F +L L + NK++ + + L LD+ NK++
Sbjct: 250 HWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIEN 309
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
L + L+ ++++NL N
Sbjct: 310 LPPLIFKDLKELSQLNLSYN 329
Score = 42.3 bits (95), Expect = 0.004
Identities = 40/215 (18%), Positives = 82/215 (38%), Gaps = 1/215 (0%)
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L+R++ + L++L L N ++ F L L KL L N+++ + +F
Sbjct: 137 LIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFED 196
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
L L + N + +N + R + + L ++ G
Sbjct: 197 LHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEG 256
Query: 334 NNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
N++ N + + + + + + +N F + L LDL NK+ P +
Sbjct: 257 NHIH-NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
K L +L++S+N +Q + L + ++L
Sbjct: 316 KDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSL 350
Score = 41.1 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 39/78 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L EL + ++ + ++ F L+ L LNL++N + + A+ F L+ L L L+
Sbjct: 292 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 351
Query: 140 HNHIEQMSSETFRHLTSL 157
I + FR L +L
Sbjct: 352 GIEISNIQQRMFRPLMNL 369
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 125 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 184
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 98.7 bits (235), Expect = 5e-20
Identities = 76/264 (28%), Positives = 125/264 (47%), Gaps = 7/264 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 151 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 210
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 211 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 270
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + R+ + +N + + +L+ELDLG N + L F LK L +L L N
Sbjct: 271 SNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNP 330
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+ I N F +L L+L ++SH +F +AP
Sbjct: 331 IQKIQANQFDYLVKLKSLSLE-----GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPH 385
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQ 346
V S K N G + N +A ++Q
Sbjct: 386 VRSCKP-NTDGISSLENLLASIIQ 408
Score = 81.4 bits (192), Expect = 8e-15
Identities = 61/227 (26%), Positives = 107/227 (47%), Gaps = 2/227 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L L L N+
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
++S+N I + F +V LK+++ G
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLV-KLKSLSLEG 352
Score = 61.7 bits (143), Expect = 7e-09
Identities = 66/256 (25%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N+T + L N I ++ + F++ L+ L L NN+I+++ FR L L+ L LS N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
T L P VF+D+ RLE L + +N ++ F L
Sbjct: 187 TFLKPGVFEDLH------------------------RLEWLIIEDNHLSRISPPTFYGLN 222
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNR-ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
L L L N L+ + D ++ LH L L N + NK
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
I+ + TFAP+ L ++ N + N ++ + L E+ + L+ +Q+I N F
Sbjct: 283 INHLNENTFAPL-QKLDELDLGSNKIE-NLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 371 YNEHLVALDLSWNKLS 386
Y L +L L ++S
Sbjct: 341 YLVKLKSLSLEGIEIS 356
Score = 48.0 bits (109), Expect = 9e-05
Identities = 47/200 (23%), Positives = 79/200 (39%), Gaps = 1/200 (0%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L NL + L D F + L+KL L N+++ I F L L LS NR
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
I N + R TF + +SL + N L + Q +P +
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRL 249
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H + L + + F +L L + NK++ + + L LD+ NK++
Sbjct: 250 HWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIEN 309
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
L + L+ ++++NL N
Sbjct: 310 LPPLIFKDLKELSQLNLSYN 329
Score = 42.3 bits (95), Expect = 0.004
Identities = 40/215 (18%), Positives = 82/215 (38%), Gaps = 1/215 (0%)
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L+R++ + L++L L N ++ F L L KL L N+++ + +F
Sbjct: 137 LIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFED 196
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
L L + N + +N + R + + L ++ G
Sbjct: 197 LHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEG 256
Query: 334 NNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
N++ N + + + + + + +N F + L LDL NK+ P +
Sbjct: 257 NHIH-NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
K L +L++S+N +Q + L + ++L
Sbjct: 316 KDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSL 350
Score = 41.1 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 39/78 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L EL + ++ + ++ F L+ L LNL++N + + A+ F L+ L L L+
Sbjct: 292 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 351
Query: 140 HNHIEQMSSETFRHLTSL 157
I + FR L +L
Sbjct: 352 GIEISNIQQRMFRPLMNL 369
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 125 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 184
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 98.7 bits (235), Expect = 5e-20
Identities = 76/264 (28%), Positives = 125/264 (47%), Gaps = 7/264 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 118 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 177
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 178 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 237
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + R+ + +N + + +L+ELDLG N + L F LK L +L L N
Sbjct: 238 SNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNP 297
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+ I N F +L L+L ++SH +F +AP
Sbjct: 298 IQKIQANQFDYLVKLKSLSLE-----GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPH 352
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQ 346
V S K N G + N +A ++Q
Sbjct: 353 VRSCKP-NTDGISSLENLLASIIQ 375
Score = 81.4 bits (192), Expect = 8e-15
Identities = 61/227 (26%), Positives = 107/227 (47%), Gaps = 2/227 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 94 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 153
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 154 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 213
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L L L N+
Sbjct: 214 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 273
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
++S+N I + F +V LK+++ G
Sbjct: 274 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLV-KLKSLSLEG 319
Score = 61.7 bits (143), Expect = 7e-09
Identities = 66/256 (25%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N+T + L N I ++ + F++ L+ L L NN+I+++ FR L L+ L LS N +
Sbjct: 94 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 153
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
T L P VF+D+ RLE L + +N ++ F L
Sbjct: 154 TFLKPGVFEDLH------------------------RLEWLIIEDNHLSRISPPTFYGLN 189
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNR-ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
L L L N L+ + D ++ LH L L N + NK
Sbjct: 190 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 249
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
I+ + TFAP+ L ++ N + N ++ + L E+ + L+ +Q+I N F
Sbjct: 250 INHLNENTFAPL-QKLDELDLGSNKIE-NLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 307
Query: 371 YNEHLVALDLSWNKLS 386
Y L +L L ++S
Sbjct: 308 YLVKLKSLSLEGIEIS 323
Score = 48.0 bits (109), Expect = 9e-05
Identities = 47/200 (23%), Positives = 79/200 (39%), Gaps = 1/200 (0%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L NL + L D F + L+KL L N+++ I F L L LS NR
Sbjct: 98 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 157
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
I N + R TF + +SL + N L + Q +P +
Sbjct: 158 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRL 216
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H + L + + F +L L + NK++ + + L LD+ NK++
Sbjct: 217 HWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIEN 276
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
L + L+ ++++NL N
Sbjct: 277 LPPLIFKDLKELSQLNLSYN 296
Score = 42.3 bits (95), Expect = 0.004
Identities = 40/215 (18%), Positives = 82/215 (38%), Gaps = 1/215 (0%)
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L+R++ + L++L L N ++ F L L KL L N+++ + +F
Sbjct: 104 LIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFED 163
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
L L + N + +N + R + + L ++ G
Sbjct: 164 LHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEG 223
Query: 334 NNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
N++ N + + + + + + +N F + L LDL NK+ P +
Sbjct: 224 NHIH-NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 282
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
K L +L++S+N +Q + L + ++L
Sbjct: 283 KDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSL 317
Score = 41.1 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 39/78 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L EL + ++ + ++ F L+ L LNL++N + + A+ F L+ L L L+
Sbjct: 259 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 318
Query: 140 HNHIEQMSSETFRHLTSL 157
I + FR L +L
Sbjct: 319 GIEISNIQQRMFRPLMNL 336
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 92 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 151
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 98.7 bits (235), Expect = 5e-20
Identities = 76/264 (28%), Positives = 125/264 (47%), Gaps = 7/264 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 151 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 210
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 211 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 270
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L + R+ + +N + + +L+ELDLG N + L F LK L +L L N
Sbjct: 271 SNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNP 330
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+ I N F +L L+L ++SH +F +AP
Sbjct: 331 IQKIQANQFDYLVKLKSLSLE-----GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPH 385
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQ 346
V S K N G + N +A ++Q
Sbjct: 386 VRSCKP-NTDGISSLENLLASIIQ 408
Score = 81.4 bits (192), Expect = 8e-15
Identities = 61/227 (26%), Positives = 107/227 (47%), Gaps = 2/227 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L L L N+
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 306
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
++S+N I + F +V LK+++ G
Sbjct: 307 IENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLV-KLKSLSLEG 352
Score = 61.7 bits (143), Expect = 7e-09
Identities = 66/256 (25%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N+T + L N I ++ + F++ L+ L L NN+I+++ FR L L+ L LS N +
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
T L P VF+D+ RLE L + +N ++ F L
Sbjct: 187 TFLKPGVFEDLH------------------------RLEWLIIEDNHLSRISPPTFYGLN 222
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNR-ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
L L L N L+ + D ++ LH L L N + NK
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
I+ + TFAP+ L ++ N + N ++ + L E+ + L+ +Q+I N F
Sbjct: 283 INHLNENTFAPL-QKLDELDLGSNKIE-NLPPLIFKDLKELSQLNLSYNPIQKIQANQFD 340
Query: 371 YNEHLVALDLSWNKLS 386
Y L +L L ++S
Sbjct: 341 YLVKLKSLSLEGIEIS 356
Score = 48.0 bits (109), Expect = 9e-05
Identities = 47/200 (23%), Positives = 79/200 (39%), Gaps = 1/200 (0%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L NL + L D F + L+KL L N+++ I F L L LS NR
Sbjct: 131 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 190
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
I N + R TF + +SL + N L + Q +P +
Sbjct: 191 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRL 249
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H + L + + F +L L + NK++ + + L LD+ NK++
Sbjct: 250 HWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIEN 309
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
L + L+ ++++NL N
Sbjct: 310 LPPLIFKDLKELSQLNLSYN 329
Score = 42.3 bits (95), Expect = 0.004
Identities = 40/215 (18%), Positives = 82/215 (38%), Gaps = 1/215 (0%)
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L+R++ + L++L L N ++ F L L KL L N+++ + +F
Sbjct: 137 LIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFED 196
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSG 333
L L + N + +N + R + + L ++ G
Sbjct: 197 LHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEG 256
Query: 334 NNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
N++ N + + + + + + +N F + L LDL NK+ P +
Sbjct: 257 NHIH-NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
K L +L++S+N +Q + L + ++L
Sbjct: 316 KDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSL 350
Score = 41.1 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 39/78 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L EL + ++ + ++ F L+ L LNL++N + + A+ F L+ L L L+
Sbjct: 292 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 351
Query: 140 HNHIEQMSSETFRHLTSL 157
I + FR L +L
Sbjct: 352 GIEISNIQQRMFRPLMNL 369
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 125 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 184
>AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 variant
protein.
Length = 627
Score = 93.5 bits (222), Expect = 2e-18
Identities = 61/195 (31%), Positives = 99/195 (50%), Gaps = 1/195 (0%)
Query: 89 HIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+ ++S
Sbjct: 26 YLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISP 85
Query: 149 ETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
TF L SL L+L NN ++ L + L + + +L LDL N + +L F +L +
Sbjct: 86 PTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 145
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
R+ + +N + + +L+ELDLG N + L F LK L +L L N + I
Sbjct: 146 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 205
Query: 268 DNMFGRNRELHVLTL 282
N F +L L+L
Sbjct: 206 ANQFDYLVKLKSLSL 220
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/198 (27%), Positives = 92/198 (46%), Gaps = 2/198 (1%)
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
+L +N I +S FR L SL L L++N+I+ L +F L +L L + DN L+ ++P
Sbjct: 26 YLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISP 85
Query: 197 EVFKDIQHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
F + L + +L R+ + + +PRL LDL N L + FIS L
Sbjct: 86 PTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 145
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L + N+++ + +N F ++L L L N+ ++S+N I +
Sbjct: 146 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 205
Query: 316 LQTFAPVVDSLKTINFSG 333
F +V LK+++ G
Sbjct: 206 ANQFDYLV-KLKSLSLEG 222
Score = 52.8 bits (121), Expect = 3e-06
Identities = 31/99 (31%), Positives = 55/99 (55%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L + + + + + +F LQ L L+L N + ++ F+ L L++L+L +N I
Sbjct: 142 NLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPI 201
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLS 182
+++ + F +L LK+L L +IS + R+FR L LS
Sbjct: 202 QKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLS 240
Score = 48.0 bits (109), Expect = 9e-05
Identities = 33/127 (25%), Positives = 58/127 (45%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
+ L L+L N++ ++ F NLT L + N I ++ TF L L L L +N
Sbjct: 116 MPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 175
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
+I L +F+ L +LS L+LS NP+ + F + L+ + I +++
Sbjct: 176 KIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRP 235
Query: 226 VPRLEEL 232
+ L +
Sbjct: 236 LMNLSHI 242
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 27/226 (11%)
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
L NN+I+++ FR L L+ L LS N +T L P VF+D+
Sbjct: 27 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLH------------------ 68
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNR-ELHVL 280
RLE L + +N ++ F L L L L N L+ + D ++ LH L
Sbjct: 69 ------RLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWL 122
Query: 281 TLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNE 340
L N + NKI+ + TFAP+ L ++ N + N
Sbjct: 123 DLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPL-QKLDELDLGSNKIE-NL 180
Query: 341 IAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLS 386
++ + L E+ + L+ +Q+I N F Y L +L L ++S
Sbjct: 181 PPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEIS 226
Score = 41.1 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 39/78 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L EL + ++ + ++ F L+ L LNL++N + + A+ F L+ L L L+
Sbjct: 162 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 221
Query: 140 HNHIEQMSSETFRHLTSL 157
I + FR L +L
Sbjct: 222 GIEISNIQQRMFRPLMNL 239
Score = 37.1 bits (82), Expect = 0.16
Identities = 38/174 (21%), Positives = 66/174 (37%), Gaps = 1/174 (0%)
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L N+++ I F L L LS NR I N + R
Sbjct: 27 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 86
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
TF + +SL + N L + Q +P +H + L + + F +L
Sbjct: 87 TFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 145
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + NK++ + + L LD+ NK++ L + L+ ++++NL N
Sbjct: 146 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYN 199
Score = 37.1 bits (82), Expect = 0.16
Identities = 34/182 (18%), Positives = 68/182 (37%), Gaps = 1/182 (0%)
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
F L L KL L N+++ + +F L L + N +
Sbjct: 40 FRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVL 99
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
+N + R + + L ++ GN++ N + + + + + + +
Sbjct: 100 MNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH-NLRNLTFISCSNLTVLVMRKNKINHLNE 158
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
N F + L LDL NK+ P + K L +L++S+N +Q + L + +
Sbjct: 159 NTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSL 218
Query: 427 NL 428
+L
Sbjct: 219 SL 220
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 93.1 bits (221), Expect = 2e-18
Identities = 92/397 (23%), Positives = 175/397 (44%), Gaps = 12/397 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+E+++ + + I F L NL+ + L +N LT+V + ++ L L HN I
Sbjct: 93 NLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLG-AASSHVVSLFLQHNKI 151
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI- 202
+ + SL+ L L+ N I+ + + F + L+L+ N + L F +
Sbjct: 152 RSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLS 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+ L + + + ++ + + L PRL +LDL N + + F L L+ LKL N
Sbjct: 212 RSLLTLRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNN 270
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + D F ++HVL L N +S+N I R H + ++
Sbjct: 271 ISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWS-F 329
Query: 323 VDSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLS 381
L + S NNL L+E + L L + + L++ S+ I + F L LDL
Sbjct: 330 CQKLHELVLSFNNLTRLDEES--LAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLD 387
Query: 382 WNKLS---RFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQC 438
N++S S L +L++ N ++++ +++ + E+++ +++ CD C
Sbjct: 388 HNEISGTIEDTSGAFSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCD-C 446
Query: 439 SASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
+ ++ +L + + C P L+G + S+
Sbjct: 447 QLKWLPPWLIGRMLQAFV-TATCAHPESLKGQSIFSV 482
Score = 80.6 bits (190), Expect = 1e-14
Identities = 77/323 (23%), Positives = 141/323 (43%), Gaps = 5/323 (1%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R LNL++N L+ + F L NL E++L +N + ++ F L +L+ + L NN++ T
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL-T 129
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
V L + + L L N + + K L + + + + P +
Sbjct: 130 AVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPI 189
Query: 230 EELDLGENLFKYLTSDEFISLKR-LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
+EL+L N L F L R L L+L N+++ + F R L L L+RNR
Sbjct: 190 KELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPR-LTQLDLNRNRIR 248
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
+ N I + F + + ++ N+L + + L L
Sbjct: 249 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGL-SKMHVLHLEYNSL-VEVNSGSLYGL 306
Query: 349 PEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
+H + L+N S+ I + +++ + L L LS+N L+R + L++ L L +SHN
Sbjct: 307 TALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNS 366
Query: 409 LQTLSEQDLQRLEAIAEVNLMKN 431
+ ++E + L ++ ++L N
Sbjct: 367 ISHIAEGAFKGLRSLRVLDLDHN 389
Score = 49.6 bits (113), Expect = 3e-05
Identities = 27/89 (30%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---FRGLINLTEL 136
A +L L + ++++ I + +F GL++LRVL+L HN ++ + D F GL +L++L
Sbjct: 352 AELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKL 411
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANN 165
+L N I + + F + +LK L ++++
Sbjct: 412 NLGGNAIRSVQFDAFVKMKNLKELHISSD 440
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/203 (29%), Positives = 99/203 (48%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L+++ + ++ + I + +F+GL NL++L L HN +T++ F+ L LT L LD N
Sbjct: 160 YTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDN 219
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
I ++S F L SL L + NN + L ++ + +L+ +DL N + L F
Sbjct: 220 PITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLS 279
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + R + + + + + L ELDL N L+ F LK L+KL L N
Sbjct: 280 CDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSN 339
Query: 262 QLSVIVDNMFGRNRELHVLTLSR 284
L + N F ++L L L R
Sbjct: 340 PLMYLHKNQFESLKQLQSLDLER 362
Score = 90.6 bits (215), Expect = 1e-17
Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 4/233 (1%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
EL VN ++ S+ S N+ +L+L N + S+ F L ++ L HN I +
Sbjct: 121 ELECVNGDLKSVPMIS----NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHI 176
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
S + F L +L+ L L +N I+TL +F+ L +L+ L L DNP+T ++ +F + L
Sbjct: 177 SRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLF 236
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
L + Q+ +P+L +DL N KYLT+ F+S L L L NQ+ +
Sbjct: 237 FLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFV 296
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
+ F + L L LS N ++S N + H F
Sbjct: 297 PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQF 349
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/182 (28%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Query: 78 QPAPFVNLRELH--IVNSN-VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
+P F +L +L I++ N + I Q F GL +L L++ +N L ++ + L
Sbjct: 201 RPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLN 260
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
+ L+ N I+ +++ TF SL L L NQI + + F L L LDLS N +T+L
Sbjct: 261 WVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITEL 320
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P +FKD++ L+ L ++ + + +L+ LDL + + F +K L
Sbjct: 321 SPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Query: 255 KL 256
+
Sbjct: 381 HI 382
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/250 (24%), Positives = 101/250 (40%)
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
G + + P N+ L + + + S+ F L+ + L HN + + F GL N
Sbjct: 127 GDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L+L+HN I + F+ L L LIL +N I+ + RLF L L L + +N L
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L ++ + L ++ + + L L L N ++ F SLK
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKN 306
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L +L L N ++ + ++F + L L LS N D+ +I
Sbjct: 307 LGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIP 366
Query: 313 RFHLQTFAPV 322
+ + F P+
Sbjct: 367 NINTRMFQPM 376
Score = 48.8 bits (111), Expect = 5e-05
Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 2/200 (1%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L +N L FI +LKK+ L N + I F L +L L+ N
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ N I R + F + +SL ++ N L + Q +P++
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGL-NSLFFLSMVNNYLEALPKQMCAQ-MPQL 259
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ V L ++ + + F + L L L N++ P K S K L LD+S N +
Sbjct: 260 NWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITE 319
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
LS + L+ + ++NL N
Sbjct: 320 LSPHLFKDLKLLQKLNLSSN 339
Score = 48.0 bits (109), Expect = 9e-05
Identities = 63/249 (25%), Positives = 100/249 (40%), Gaps = 28/249 (11%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
+++L L N + L +VF L+ IF C+ R I+ + + + L+ L L N
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCI-RHISRKAFFGLCNLQILYLNHNCI 197
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXX 299
L F L +L L LD N ++ I +F L L++ N
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 300 XXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
D+ N+I TF DSL T+ F LP N+I V
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSC-DSL-TVLF----LPRNQIGFV--------------- 296
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
P+ F+ ++L LDLS N ++ L K LQ+L++S N L L + +
Sbjct: 297 -----PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFES 351
Query: 420 LEAIAEVNL 428
L+ + ++L
Sbjct: 352 LKQLQSLDL 360
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/203 (29%), Positives = 99/203 (48%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L+++ + ++ + I + +F+GL NL++L L HN +T++ F+ L LT L LD N
Sbjct: 160 YTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDN 219
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
I ++S F L SL L + NN + L ++ + +L+ +DL N + L F
Sbjct: 220 PITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLS 279
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + R + + + + + L ELDL N L+ F LK L+KL L N
Sbjct: 280 CDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSN 339
Query: 262 QLSVIVDNMFGRNRELHVLTLSR 284
L + N F ++L L L R
Sbjct: 340 PLMYLHKNQFESLKQLQSLDLER 362
Score = 90.6 bits (215), Expect = 1e-17
Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 4/233 (1%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
EL VN ++ S+ S N+ +L+L N + S+ F L ++ L HN I +
Sbjct: 121 ELECVNGDLKSVPMIS----NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHI 176
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
S + F L +L+ L L +N I+TL +F+ L +L+ L L DNP+T ++ +F + L
Sbjct: 177 SRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLF 236
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
L + Q+ +P+L +DL N KYLT+ F+S L L L NQ+ +
Sbjct: 237 FLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFV 296
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
+ F + L L LS N ++S N + H F
Sbjct: 297 PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQF 349
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/182 (28%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Query: 78 QPAPFVNLRELH--IVNSN-VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
+P F +L +L I++ N + I Q F GL +L L++ +N L ++ + L
Sbjct: 201 RPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLN 260
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
+ L+ N I+ +++ TF SL L L NQI + + F L L LDLS N +T+L
Sbjct: 261 WVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITEL 320
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P +FKD++ L+ L ++ + + +L+ LDL + + F +K L
Sbjct: 321 SPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Query: 255 KL 256
+
Sbjct: 381 HI 382
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/250 (24%), Positives = 101/250 (40%)
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
G + + P N+ L + + + S+ F L+ + L HN + + F GL N
Sbjct: 127 GDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L+L+HN I + F+ L L LIL +N I+ + RLF L L L + +N L
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L ++ + L ++ + + L L L N ++ F SLK
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKN 306
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L +L L N ++ + ++F + L L LS N D+ +I
Sbjct: 307 LGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIP 366
Query: 313 RFHLQTFAPV 322
+ + F P+
Sbjct: 367 NINTRMFQPM 376
Score = 48.8 bits (111), Expect = 5e-05
Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 2/200 (1%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L +N L FI +LKK+ L N + I F L +L L+ N
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ N I R + F + +SL ++ N L + Q +P++
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGL-NSLFFLSMVNNYLEALPKQMCAQ-MPQL 259
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ V L ++ + + F + L L L N++ P K S K L LD+S N +
Sbjct: 260 NWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITE 319
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
LS + L+ + ++NL N
Sbjct: 320 LSPHLFKDLKLLQKLNLSSN 339
Score = 48.0 bits (109), Expect = 9e-05
Identities = 63/249 (25%), Positives = 100/249 (40%), Gaps = 28/249 (11%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
+++L L N + L +VF L+ IF C+ R I+ + + + L+ L L N
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCI-RHISRKAFFGLCNLQILYLNHNCI 197
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXX 299
L F L +L L LD N ++ I +F L L++ N
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 300 XXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
D+ N+I TF DSL T+ F LP N+I V
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSC-DSL-TVLF----LPRNQIGFV--------------- 296
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
P+ F+ ++L LDLS N ++ L K LQ+L++S N L L + +
Sbjct: 297 -----PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFES 351
Query: 420 LEAIAEVNL 428
L+ + ++L
Sbjct: 352 LKQLQSLDL 360
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/203 (29%), Positives = 99/203 (48%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L+++ + ++ + I + +F+GL NL++L L HN +T++ F+ L LT L LD N
Sbjct: 160 YTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDN 219
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
I ++S F L SL L + NN + L ++ + +L+ +DL N + L F
Sbjct: 220 PITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLS 279
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + R + + + + + L ELDL N L+ F LK L+KL L N
Sbjct: 280 CDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSN 339
Query: 262 QLSVIVDNMFGRNRELHVLTLSR 284
L + N F ++L L L R
Sbjct: 340 PLMYLHKNQFESLKQLQSLDLER 362
Score = 90.6 bits (215), Expect = 1e-17
Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 4/233 (1%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
EL VN ++ S+ S N+ +L+L N + S+ F L ++ L HN I +
Sbjct: 121 ELECVNGDLKSVPMIS----NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHI 176
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
S + F L +L+ L L +N I+TL +F+ L +L+ L L DNP+T ++ +F + L
Sbjct: 177 SRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLF 236
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
L + Q+ +P+L +DL N KYLT+ F+S L L L NQ+ +
Sbjct: 237 FLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFV 296
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
+ F + L L LS N ++S N + H F
Sbjct: 297 PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQF 349
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/182 (28%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Query: 78 QPAPFVNLRELH--IVNSN-VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
+P F +L +L I++ N + I Q F GL +L L++ +N L ++ + L
Sbjct: 201 RPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLN 260
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
+ L+ N I+ +++ TF SL L L NQI + + F L L LDLS N +T+L
Sbjct: 261 WVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITEL 320
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P +FKD++ L+ L ++ + + +L+ LDL + + F +K L
Sbjct: 321 SPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Query: 255 KL 256
+
Sbjct: 381 HI 382
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/250 (24%), Positives = 101/250 (40%)
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
G + + P N+ L + + + S+ F L+ + L HN + + F GL N
Sbjct: 127 GDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L+L+HN I + F+ L L LIL +N I+ + RLF L L L + +N L
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L ++ + L ++ + + L L L N ++ F SLK
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKN 306
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L +L L N ++ + ++F + L L LS N D+ +I
Sbjct: 307 LGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIP 366
Query: 313 RFHLQTFAPV 322
+ + F P+
Sbjct: 367 NINTRMFQPM 376
Score = 48.8 bits (111), Expect = 5e-05
Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 2/200 (1%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L +N L FI +LKK+ L N + I F L +L L+ N
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ N I R + F + +SL ++ N L + Q +P++
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGL-NSLFFLSMVNNYLEALPKQMCAQ-MPQL 259
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ V L ++ + + F + L L L N++ P K S K L LD+S N +
Sbjct: 260 NWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITE 319
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
LS + L+ + ++NL N
Sbjct: 320 LSPHLFKDLKLLQKLNLSSN 339
Score = 48.0 bits (109), Expect = 9e-05
Identities = 63/249 (25%), Positives = 100/249 (40%), Gaps = 28/249 (11%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
+++L L N + L +VF L+ IF C+ R I+ + + + L+ L L N
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCI-RHISRKAFFGLCNLQILYLNHNCI 197
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXX 299
L F L +L L LD N ++ I +F L L++ N
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 300 XXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
D+ N+I TF DSL T+ F LP N+I V
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSC-DSL-TVLF----LPRNQIGFV--------------- 296
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
P+ F+ ++L LDLS N ++ L K LQ+L++S N L L + +
Sbjct: 297 -----PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFES 351
Query: 420 LEAIAEVNL 428
L+ + ++L
Sbjct: 352 LKQLQSLDL 360
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/203 (29%), Positives = 99/203 (48%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L+++ + ++ + I + +F+GL NL++L L HN +T++ F+ L LT L LD N
Sbjct: 160 YTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDN 219
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
I ++S F L SL L + NN + L ++ + +L+ +DL N + L F
Sbjct: 220 PITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLS 279
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + R + + + + + L ELDL N L+ F LK L+KL L N
Sbjct: 280 CDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSN 339
Query: 262 QLSVIVDNMFGRNRELHVLTLSR 284
L + N F ++L L L R
Sbjct: 340 PLMYLHKNQFESLKQLQSLDLER 362
Score = 90.6 bits (215), Expect = 1e-17
Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 4/233 (1%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
EL VN ++ S+ S N+ +L+L N + S+ F L ++ L HN I +
Sbjct: 121 ELECVNGDLKSVPMIS----NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHI 176
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
S + F L +L+ L L +N I+TL +F+ L +L+ L L DNP+T ++ +F + L
Sbjct: 177 SRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLF 236
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
L + Q+ +P+L +DL N KYLT+ F+S L L L NQ+ +
Sbjct: 237 FLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFV 296
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
+ F + L L LS N ++S N + H F
Sbjct: 297 PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQF 349
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/182 (28%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Query: 78 QPAPFVNLRELH--IVNSN-VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
+P F +L +L I++ N + I Q F GL +L L++ +N L ++ + L
Sbjct: 201 RPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLN 260
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
+ L+ N I+ +++ TF SL L L NQI + + F L L LDLS N +T+L
Sbjct: 261 WVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITEL 320
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P +FKD++ L+ L ++ + + +L+ LDL + + F +K L
Sbjct: 321 SPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 380
Query: 255 KL 256
+
Sbjct: 381 HI 382
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/250 (24%), Positives = 101/250 (40%)
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
G + + P N+ L + + + S+ F L+ + L HN + + F GL N
Sbjct: 127 GDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L+L+HN I + F+ L L LIL +N I+ + RLF L L L + +N L
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L ++ + L ++ + + L L L N ++ F SLK
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKN 306
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L +L L N ++ + ++F + L L LS N D+ +I
Sbjct: 307 LGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIP 366
Query: 313 RFHLQTFAPV 322
+ + F P+
Sbjct: 367 NINTRMFQPM 376
Score = 48.8 bits (111), Expect = 5e-05
Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 2/200 (1%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L +N L FI +LKK+ L N + I F L +L L+ N
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ N I R + F + +SL ++ N L + Q +P++
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGL-NSLFFLSMVNNYLEALPKQMCAQ-MPQL 259
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ V L ++ + + F + L L L N++ P K S K L LD+S N +
Sbjct: 260 NWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITE 319
Query: 412 LSEQDLQRLEAIAEVNLMKN 431
LS + L+ + ++NL N
Sbjct: 320 LSPHLFKDLKLLQKLNLSSN 339
Score = 48.0 bits (109), Expect = 9e-05
Identities = 63/249 (25%), Positives = 100/249 (40%), Gaps = 28/249 (11%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
+++L L N + L +VF L+ IF C+ R I+ + + + L+ L L N
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCI-RHISRKAFFGLCNLQILYLNHNCI 197
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXX 299
L F L +L L LD N ++ I +F L L++ N
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 300 XXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
D+ N+I TF DSL T+ F LP N+I V
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSC-DSL-TVLF----LPRNQIGFV--------------- 296
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
P+ F+ ++L LDLS N ++ L K LQ+L++S N L L + +
Sbjct: 297 -----PEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFES 351
Query: 420 LEAIAEVNL 428
L+ + ++L
Sbjct: 352 LKQLQSLDL 360
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 92.3 bits (219), Expect = 4e-18
Identities = 79/278 (28%), Positives = 124/278 (44%), Gaps = 16/278 (5%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
+AA CP C C D H VAC++ ++ +P D + + N
Sbjct: 43 QAAAQRCPQACIC----DNSRRH---VACRYQNLTEVP------DAIPELTQRLDLQGNL 89
Query: 70 LTIGPIFT-QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
L + P Q P +L L + + V + + +F GL L +LNL N+L + +
Sbjct: 90 LKVIPAAAFQGVP--HLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 147
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
GL +L L L+ N +E++ TF L +L TL LA+N + L + F+ L ++ L LS
Sbjct: 148 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 207
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L+ L PE + LR L+ + + L L+LG N Y ++ +
Sbjct: 208 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 267
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L++L LDG L + F LH L L N+
Sbjct: 268 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQ 305
Score = 56.0 bits (129), Expect = 3e-07
Identities = 50/210 (23%), Positives = 88/210 (41%), Gaps = 3/210 (1%)
Query: 220 TQIYHLVPRL-EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
T++ +P L + LDL NL K + + F + L L L ++ ++ + F L
Sbjct: 70 TEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 129
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPL 338
+L L+ N ++ N ++ TF + +L T+N + N L
Sbjct: 130 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFG-ALGALATLNLAHNALVY 188
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
A+ Q L + + L++ +L + L L L N+L P +LS+ +
Sbjct: 189 LP-AMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARG 247
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L RL++ HN L E+D L + E+ L
Sbjct: 248 LARLELGHNPLTYAGEEDGLALPGLRELLL 277
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/184 (25%), Positives = 75/184 (40%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++ PS+ + +F GL +L L+L H + + A GL L L+L N + +S
Sbjct: 446 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 505
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ L L L N+ + R L L L L DN + L P + LR
Sbjct: 506 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRW 565
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ LE+L L N + + + L L +L+L GN L +
Sbjct: 566 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 625
Query: 268 DNMF 271
D F
Sbjct: 626 DGAF 629
Score = 51.2 bits (117), Expect = 9e-06
Identities = 51/210 (24%), Positives = 80/210 (38%), Gaps = 1/210 (0%)
Query: 128 RGLINLTEL-HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
RG + T+L L NH + F L L +L L + I+ L + L +L L L
Sbjct: 437 RGFRSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYL 496
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
SDN L L+ + L R ++ +P L L L +N L +
Sbjct: 497 SDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGD 556
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
+ L+ + L GN+++ + G REL L L RN+ +
Sbjct: 557 LGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQL 616
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
S N + F PV SL+ + + + L
Sbjct: 617 SGNPLRALRDGAFQPVGRSLQHLFLNSSGL 646
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/114 (28%), Positives = 48/114 (42%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ +R L + ++ + + + GL LR L+L HN L ++ L L L HN
Sbjct: 198 LRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNP 257
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
+ E L L+ L+L + L R F +L LDL N L L P
Sbjct: 258 LTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 42/177 (23%), Positives = 76/177 (42%), Gaps = 6/177 (3%)
Query: 65 DRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVA 124
+R FL + + P +L LH+ ++ V + + LR + L+ N +T V
Sbjct: 521 ERNRFLQVPGAALRALP--SLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 578
Query: 125 DNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSI 183
L +LHLD N + ++ + L +L L L+ N + L F+ + + L
Sbjct: 579 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 638
Query: 184 LDLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
L L+ + L + P F + L+ ++ LR + + +LE +DL N F
Sbjct: 639 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRAL--PALPSLSQLELIDLSSNPF 693
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 329 INFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRF 388
++ GN L + A Q +P + + L + ++ + + F L+ L+L+ N L
Sbjct: 83 LDLQGNLLKVIPAA-AFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLREL 141
Query: 389 PFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
P + L L+RL++ N L+ L L A+A +NL N
Sbjct: 142 PQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN 184
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 92.3 bits (219), Expect = 4e-18
Identities = 79/278 (28%), Positives = 124/278 (44%), Gaps = 16/278 (5%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
+AA CP C C D H VAC++ ++ +P D + + N
Sbjct: 27 QAAAQRCPQACIC----DNSRRH---VACRYQNLTEVP------DAIPELTQRLDLQGNL 73
Query: 70 LTIGPIFT-QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
L + P Q P +L L + + V + + +F GL L +LNL N+L + +
Sbjct: 74 LKVIPAAAFQGVP--HLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 131
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
GL +L L L+ N +E++ TF L +L TL LA+N + L + F+ L ++ L LS
Sbjct: 132 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 191
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L+ L PE + LR L+ + + L L+LG N Y ++ +
Sbjct: 192 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 251
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L++L LDG L + F LH L L N+
Sbjct: 252 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQ 289
Score = 56.4 bits (130), Expect = 3e-07
Identities = 47/184 (25%), Positives = 75/184 (40%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++ PS+ + +F GL +L L+L H + + A GL L L+L N + +S
Sbjct: 430 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 489
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ L L L N+ + R L L L L DN + L P + LR
Sbjct: 490 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 549
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ LE+L L N + + + L L +L+L GN L +
Sbjct: 550 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 609
Query: 268 DNMF 271
D F
Sbjct: 610 DGAF 613
Score = 56.0 bits (129), Expect = 3e-07
Identities = 50/210 (23%), Positives = 88/210 (41%), Gaps = 3/210 (1%)
Query: 220 TQIYHLVPRL-EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
T++ +P L + LDL NL K + + F + L L L ++ ++ + F L
Sbjct: 54 TEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 113
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPL 338
+L L+ N ++ N ++ TF + +L T+N + N L
Sbjct: 114 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFG-ALGALATLNLAHNALVY 172
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
A+ Q L + + L++ +L + L L L N+L P +LS+ +
Sbjct: 173 LP-AMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARG 231
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L RL++ HN L E+D L + E+ L
Sbjct: 232 LARLELGHNPLTYAGEEDGLALPGLRELLL 261
Score = 51.2 bits (117), Expect = 9e-06
Identities = 51/210 (24%), Positives = 80/210 (38%), Gaps = 1/210 (0%)
Query: 128 RGLINLTEL-HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
RG + T+L L NH + F L L +L L + I+ L + L +L L L
Sbjct: 421 RGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYL 480
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
SDN L L+ + L R ++ +P L L L +N L +
Sbjct: 481 SDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGD 540
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
+ L+ + L GN+++ + G REL L L RN+ +
Sbjct: 541 LGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQL 600
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
S N + F PV SL+ + + + L
Sbjct: 601 SGNPLRALRDGAFQPVGRSLQHLFLNSSGL 630
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/114 (28%), Positives = 48/114 (42%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ +R L + ++ + + + GL LR L+L HN L ++ L L L HN
Sbjct: 182 LRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNP 241
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
+ E L L+ L+L + L R F +L LDL N L L P
Sbjct: 242 LTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP 295
Score = 39.9 bits (89), Expect = 0.023
Identities = 42/177 (23%), Positives = 76/177 (42%), Gaps = 6/177 (3%)
Query: 65 DRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVA 124
+R FL + + P +L LH+ ++ V + + LR + L+ N +T V
Sbjct: 505 ERNRFLQVPGAALRALP--SLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 562
Query: 125 DNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSI 183
L +LHLD N + ++ + L +L L L+ N + L F+ + + L
Sbjct: 563 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 622
Query: 184 LDLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
L L+ + L + P F + L+ ++ LR + + +LE +DL N F
Sbjct: 623 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRAL--PALPSLSQLELIDLSSNPF 677
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 329 INFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRF 388
++ GN L + A Q +P + + L + ++ + + F L+ L+L+ N L
Sbjct: 67 LDLQGNLLKVIPAA-AFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLREL 125
Query: 389 PFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
P + L L+RL++ N L+ L L A+A +NL N
Sbjct: 126 PQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN 168
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 91.5 bits (217), Expect = 7e-18
Identities = 68/252 (26%), Positives = 115/252 (45%), Gaps = 3/252 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ + + + SF GL +L+ L L HN L + F GL NL LHL+ N +
Sbjct: 119 LLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ S F L +L+ L++ N++ ++ FR LA L L L+ L +++ + +Q
Sbjct: 179 AIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQS 238
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L R+ + VP L+ LDL +N + + +F ++ LK+L L+ +
Sbjct: 239 LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEEL 298
Query: 265 VIVDNMFGRN-RELHVLTLSRN-RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
V +D N EL L ++ N R +++N + H QT A
Sbjct: 299 VSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT-AES 357
Query: 323 VDSLKTINFSGN 334
+ +L+ + GN
Sbjct: 358 LPNLQEVGLHGN 369
Score = 74.9 bits (176), Expect = 7e-13
Identities = 76/302 (25%), Positives = 118/302 (39%), Gaps = 2/302 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N++ V L NLTEL L N F L L +L L NQ++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
L F LA L L L+ N L + P F + +L LLR I+++ + ++P L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E L +G N + F L L+ L L G L I D + L L+ N+
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
D++ N + R FA ++ LK + + ++ L LP
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQRVGPGDFANML-HLKELGLNNMEELVSIDKFALVNLP 310
Query: 350 EIHGVGLA-NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
E+ + + N L I F + + L L+ N LS + LQ + + N
Sbjct: 311 ELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTAESLPNLQEVGLHGNP 370
Query: 409 LQ 410
++
Sbjct: 371 IR 372
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/200 (28%), Positives = 88/200 (44%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL EL + ++ F L L L+L N LT + +F GL +L EL+L+HN +
Sbjct: 94 NLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQL 153
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+++ F L++L L L +N + + SR F ML L IL + N + + F+ +
Sbjct: 154 YRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLA 213
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+LR LR I+ + LE L +N + + LK L L+ N L
Sbjct: 214 NLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPL 273
Query: 264 SVIVDNMFGRNRELHVLTLS 283
+ F L L L+
Sbjct: 274 QRVGPGDFANMLHLKELGLN 293
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 4/209 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A +L+EL++ ++ + I +F GL NL L+L N L ++ + F L NL L +
Sbjct: 138 AGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIG 197
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N ++ + FR L +L++L+LA + + L L L DN L +
Sbjct: 198 GNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRAL 257
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF--ISLKRLKKLK 257
+ + L+ + L+R+ + + L+EL L N+ + ++ D+F ++L L KL
Sbjct: 258 EQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNMEELVSIDKFALVNLPELTKLD 316
Query: 258 LDGN-QLSVIVDNMFGRNRELHVLTLSRN 285
+ N +LS I F ++ L L+ N
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNN 345
Score = 63.3 bits (147), Expect = 2e-09
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 4/217 (1%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
FLT P PA + L + ++++ + Q L NL L+L+ N+ + +F
Sbjct: 59 FLTAVP----PALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH 114
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L LHL+ N + ++ +F L SL+ L L +NQ+ + R F L+ L L L+
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L ++ F+ + +L I + I + + L L L + ++
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L+ L NQL+ + + L L L++N
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Score = 59.3 bits (137), Expect = 4e-08
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 2/212 (0%)
Query: 217 RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE 276
R++ + L ELDL +N F +F +L +L L L+ NQL+ + D+ F
Sbjct: 83 RVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS 142
Query: 277 LHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
L L L+ N+ ++ N + + F ++ +L+ + GN +
Sbjct: 143 LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE-MLPNLEILMIGGNKV 201
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + + L + + LA ++L+EI + L +L N+L+R P + L +
Sbjct: 202 DAI-LDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQV 260
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L+ LD++ N LQ + D + + E+ L
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGL 292
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 91.5 bits (217), Expect = 7e-18
Identities = 68/252 (26%), Positives = 115/252 (45%), Gaps = 3/252 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ + + + SF GL +L+ L L HN L + F GL NL LHL+ N +
Sbjct: 119 LLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ S F L +L+ L++ N++ ++ FR LA L L L+ L +++ + +Q
Sbjct: 179 AIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQS 238
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L R+ + VP L+ LDL +N + + +F ++ LK+L L+ +
Sbjct: 239 LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEEL 298
Query: 265 VIVDNMFGRN-RELHVLTLSRN-RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
V +D N EL L ++ N R +++N + H QT A
Sbjct: 299 VSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT-AES 357
Query: 323 VDSLKTINFSGN 334
+ +L+ + GN
Sbjct: 358 LPNLQEVGLHGN 369
Score = 74.9 bits (176), Expect = 7e-13
Identities = 76/302 (25%), Positives = 118/302 (39%), Gaps = 2/302 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N++ V L NLTEL L N F L L +L L NQ++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
L F LA L L L+ N L + P F + +L LLR I+++ + ++P L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E L +G N + F L L+ L L G L I D + L L+ N+
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
D++ N + R FA ++ LK + + ++ L LP
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQRVGPGDFANML-HLKELGLNNMEELVSIDKFALVNLP 310
Query: 350 EIHGVGLA-NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
E+ + + N L I F + + L L+ N LS + LQ + + N
Sbjct: 311 ELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTAESLPNLQEVGLHGNP 370
Query: 409 LQ 410
++
Sbjct: 371 IR 372
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/200 (28%), Positives = 88/200 (44%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL EL + ++ F L L L+L N LT + +F GL +L EL+L+HN +
Sbjct: 94 NLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQL 153
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+++ F L++L L L +N + + SR F ML L IL + N + + F+ +
Sbjct: 154 YRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLA 213
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+LR LR I+ + LE L +N + + LK L L+ N L
Sbjct: 214 NLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPL 273
Query: 264 SVIVDNMFGRNRELHVLTLS 283
+ F L L L+
Sbjct: 274 QRVGPGDFANMLHLKELGLN 293
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 4/209 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A +L+EL++ ++ + I +F GL NL L+L N L ++ + F L NL L +
Sbjct: 138 AGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIG 197
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N ++ + FR L +L++L+LA + + L L L DN L +
Sbjct: 198 GNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRAL 257
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF--ISLKRLKKLK 257
+ + L+ + L+R+ + + L+EL L N+ + ++ D+F ++L L KL
Sbjct: 258 EQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNMEELVSIDKFALVNLPELTKLD 316
Query: 258 LDGN-QLSVIVDNMFGRNRELHVLTLSRN 285
+ N +LS I F ++ L L+ N
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNN 345
Score = 63.3 bits (147), Expect = 2e-09
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 4/217 (1%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
FLT P PA + L + ++++ + Q L NL L+L+ N+ + +F
Sbjct: 59 FLTAVP----PALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH 114
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L LHL+ N + ++ +F L SL+ L L +NQ+ + R F L+ L L L+
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L ++ F+ + +L I + I + + L L L + ++
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L+ L NQL+ + + L L L++N
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Score = 59.3 bits (137), Expect = 4e-08
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 2/212 (0%)
Query: 217 RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE 276
R++ + L ELDL +N F +F +L +L L L+ NQL+ + D+ F
Sbjct: 83 RVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS 142
Query: 277 LHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
L L L+ N+ ++ N + + F ++ +L+ + GN +
Sbjct: 143 LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE-MLPNLEILMIGGNKV 201
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + + L + + LA ++L+EI + L +L N+L+R P + L +
Sbjct: 202 DAI-LDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQV 260
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L+ LD++ N LQ + D + + E+ L
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGL 292
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 91.1 bits (216), Expect = 1e-17
Identities = 63/203 (31%), Positives = 102/203 (50%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L++ + + I SF L++L +L L+ N++ ++ F GL NL L L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+S+ F +L+ LK L L NN I ++ S F + L LDL + L+ ++ F+ +
Sbjct: 137 TTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR C LR I + L+ +L+ELDL N + F L L+KL + +Q
Sbjct: 197 SNLRYLNLAMCNLREI-PNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+ VI N F + L + L+ N
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHN 277
Score = 63.3 bits (147), Expect = 2e-09
Identities = 51/225 (22%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+L+L +N + + FK ++HL I + R +R I ++ + L L+L +N +
Sbjct: 80 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 139
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
++ F+ L +LK+L L N + I F R L L L +
Sbjct: 140 SNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNL 199
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
++ + + P++ L ++ SGN+L Q L + + + +Q
Sbjct: 200 RY-LNLAMCNLREIPNLTPLI-KLDELDLSGNHLSAIRPGS-FQGLMHLQKLWMIQSQIQ 256
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
I +N F + LV ++L+ N L+ P L + L+R+ + HN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 60.9 bits (141), Expect = 1e-08
Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 22/280 (7%)
Query: 4 LVVYNTEAAGTICPDECTCTMTF-----------DLEEGHTTQVACQHGH---MRIIPVD 49
LVV A T CP C+C+ F ++ +G +T + H ++II V+
Sbjct: 36 LVVAGLVRAQT-CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVN 94
Query: 50 YMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNL 109
H+ I+ + + IG NL L + ++ + +I +F L L
Sbjct: 95 SFKHLRHLEILQLSRNHIRTIEIGAF----NGLANLNTLELFDNRLTTISNGAFVYLSKL 150
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDH-NHIEQMSSETFRHLTSLKTLILANNQIS 168
+ L L +N + S+ + F + +L L L + +S F L++L+ L LA +
Sbjct: 151 KELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLR 210
Query: 169 TLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPR 228
+ + L KL LDLS N L+ + P F+ + HL+ + ++ I + +
Sbjct: 211 EIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQS 268
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVD 268
L E++L N L D F L L+++ L N S D
Sbjct: 269 LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWSCNCD 308
Score = 49.6 bits (113), Expect = 3e-05
Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 5/202 (2%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L+L EN + + + F L+ L+ L+L N + I F L+ L L NR
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIS 140
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VLQILPE 350
+ +N I+ F + SL+ ++ G L+ I+ + L
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRI-PSLRRLDL-GELKRLSYISEGAFEGLSN 198
Query: 351 IHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQ 410
+ + LA +L+EIP T L LDLS N LS LQ+L + +++Q
Sbjct: 199 LRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQ 256
Query: 411 TLSEQDLQRLEAIAEVNLMKNN 432
+ L+++ E+NL NN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNN 278
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/270 (19%), Positives = 102/270 (37%), Gaps = 4/270 (1%)
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
R+ ++ I + + LE L L N + + F L L L+L N+L+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
I + F +L L L N D+ K + + + +
Sbjct: 139 ISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L+ +N + NL EI + ++ ++ + L+ L I F HL L + +++
Sbjct: 199 LRYLNLAMCNL--REIPNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLL 445
+ L ++++HN L L L + ++L N W C+ C +
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWSCN-CDILWLSW 314
Query: 446 YMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ ++T +C++P L+G G L
Sbjct: 315 WIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 90.6 bits (215), Expect = 1e-17
Identities = 87/358 (24%), Positives = 144/358 (40%), Gaps = 9/358 (2%)
Query: 76 FTQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
F P L+EL ++ N+ + ++ + GL L+ L L N++TSV D+F GL+
Sbjct: 176 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 235
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L LD N + ++ +L +L+ L LA N+IS++ F L+ L +L L +N +
Sbjct: 236 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 295
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L+ F + +L L Q +P L+EL N + F
Sbjct: 296 SLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSISVIPDGAFDGNPL 354
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L+ + L N LS + ++ F +LH L + R ++ KI
Sbjct: 355 LRTIHLYDNPLSFVGNSAFHNLSDLHSLVI-RGASMVQQFPNLTGTVHLESLTLTGTKIS 413
Query: 313 RFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYN 372
L+T++ S NN+ L EI L + +I + F
Sbjct: 414 SIP-NNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEI---SLQRNQIYQIKEGTFQGL 469
Query: 373 EHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMK 430
L LDLS N + + + + LD+S N+L + + L L + V K
Sbjct: 470 ISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFK 527
Score = 85.4 bits (202), Expect = 5e-16
Identities = 91/379 (24%), Positives = 153/379 (40%), Gaps = 11/379 (2%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L+++ NN+T + D F+ L EL L N + + + L LK L L NNQ+ T
Sbjct: 141 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 200
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ S R L+ L L L N +T + + F+ + LR L + +P L
Sbjct: 201 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 260
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
+ L L N + F +L L L L N++ + + F L L L+ N
Sbjct: 261 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE 320
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQIL 348
S N I F L+TI+ N PL+ + L
Sbjct: 321 FPQAIKALPSLKELGFHS-NSISVIPDGAFDGN-PLLRTIHLYDN--PLSFVGNSAFHNL 376
Query: 349 PEIHGVGLANLSL-QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
++H + + S+ Q+ P T HL +L L+ K+S P L + K L+ LD+S+N
Sbjct: 377 SDLHSLVIRGASMVQQFPN--LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 434
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN-WHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLR 466
++ L A+ E++L +N + + + ++ + + I + +
Sbjct: 435 NIRDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFAT 492
Query: 467 LRGATFGSLSFEQLDPCPT 485
L T +SF +L PT
Sbjct: 493 LGPITNLDVSFNELTSFPT 511
Score = 62.1 bits (144), Expect = 5e-09
Identities = 43/135 (31%), Positives = 67/135 (49%), Gaps = 5/135 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L L + + + SI + LR L+L++NN+ + +F G L E+ L N
Sbjct: 400 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQRNQ 457
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I Q+ TF+ L SL+ L L+ N I + SR F L ++ LD+S N LT E +
Sbjct: 458 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGL 517
Query: 203 QHLRI---FKCRRCL 214
L++ FK + L
Sbjct: 518 NQLKLVGNFKLKEAL 532
Score = 60.9 bits (141), Expect = 1e-08
Identities = 74/347 (21%), Positives = 133/347 (38%), Gaps = 6/347 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L I +N+ + + +F L L L N+L+ + GL L L L +N ++ +
Sbjct: 143 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 202
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE R L++L++L L N I+++ F L +L L L DN LT++ ++ L+
Sbjct: 203 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 262
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ I + + L L L N + L+ F L L+ L L+ N L
Sbjct: 263 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF- 321
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
L L N + N + F + D L
Sbjct: 322 PQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSD-LH 380
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
++ G ++ + + + + L + IP N + L LDLS+N +
Sbjct: 381 SLVIRGASMVQQFPNLTGTV--HLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRD 438
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
P + L+ + + N++ + E Q L ++ ++L +N H
Sbjct: 439 LP--SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 483
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V + L +P+ + + ALD+S N +++ P FL+ L ++ N L +
Sbjct: 122 VDCSGKGLTAVPEGLSAFTQ---ALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 178
Query: 414 EQDLQRLEAIAEVNLMKN 431
+ L L+ + + L N
Sbjct: 179 PKALSGLKELKVLTLQNN 196
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 90.2 bits (214), Expect = 2e-17
Identities = 87/358 (24%), Positives = 144/358 (40%), Gaps = 9/358 (2%)
Query: 76 FTQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
F P L+EL ++ N+ + ++ + GL L+ L L N++TSV D+F GL+
Sbjct: 71 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 130
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L LD N + ++ +L +L+ L LA N+IS++ F L+ L +L L +N +
Sbjct: 131 LRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 190
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L+ F + +L L Q +P L+EL N + F
Sbjct: 191 SLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSISVIPDGAFDGNPL 249
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L+ + L N LS + ++ F +LH L + R ++ KI
Sbjct: 250 LRTIHLYDNPLSFVGNSAFHNLSDLHSLVI-RGASMVQQFPNLTGTVHLESLTLTGTKIS 308
Query: 313 RFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYN 372
L+T++ S NN+ L EI L + +I + F
Sbjct: 309 SIP-NNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEI---SLQRNQIYQIKEGTFQGL 364
Query: 373 EHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMK 430
L LDLS N + + + + LD+S N+L + + L L + V K
Sbjct: 365 ISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFK 422
Score = 64.1 bits (149), Expect = 1e-09
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 3/203 (1%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L+ N L+ ++P+ ++ L++ + L+ + ++ + L+ L L N +
Sbjct: 62 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 121
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
D F L +L+ L LD N L+ + + L LTL+ N+
Sbjct: 122 EDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 181
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQE 363
+ +NKI F +D+L+T++ + NN L E ++ LP + +G + S+
Sbjct: 182 LHLHNNKIRSLSQHCF-DGLDNLETLDLNYNN--LGEFPQAIKALPSLKELGFHSNSISV 238
Query: 364 IPQNFFTYNEHLVALDLSWNKLS 386
IP F N L + L N LS
Sbjct: 239 IPDGAFDGNPLLRTIHLYDNPLS 261
Score = 55.6 bits (128), Expect = 4e-07
Identities = 69/325 (21%), Positives = 124/325 (38%), Gaps = 6/325 (1%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N+L+ + GL L L L +N ++ + SE R L++L++L L N I++
Sbjct: 60 QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS 119
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ F L +L L L DN LT++ ++ L+ + I + + L
Sbjct: 120 VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSL 179
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
L L N + L+ F L L+ L L+ N L L L N
Sbjct: 180 VVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSISV 238
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
+ N + F + D L ++ G ++ + +
Sbjct: 239 IPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSD-LHSLVIRGASMVQQFPNLTGTV-- 295
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L + IP N + L LDLS+N + P + L+ + + N++
Sbjct: 296 HLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQI 353
Query: 410 QTLSEQDLQRLEAIAEVNLMKNNWH 434
+ E Q L ++ ++L +N H
Sbjct: 354 YQIKEGTFQGLISLRILDLSRNLIH 378
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 90.2 bits (214), Expect = 2e-17
Identities = 65/236 (27%), Positives = 108/236 (45%), Gaps = 4/236 (1%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
EL VN ++ S+ S N+ +L+L N + S+ F L ++ L HN I +
Sbjct: 121 ELECVNGDLKSVPMIS----NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHI 176
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
S + F L +L+ L L +N I+TL +F+ L +L+ L L DNP+T ++ +F + L
Sbjct: 177 SRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLF 236
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
L + Q+ +P+L +DL N KYLT+ F+S L L L N ++ +
Sbjct: 237 FLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITEL 296
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
++F + L L LS N D+ +I + + F P+
Sbjct: 297 SPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPM 352
Score = 88.6 bits (210), Expect = 5e-17
Identities = 53/190 (27%), Positives = 98/190 (51%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L+++ + ++ + I + +F+GL NL++L L HN +T++ F+ L LT L LD N
Sbjct: 160 YTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDN 219
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
I ++S F L SL L + NN + L ++ + +L+ +DL N + L F
Sbjct: 220 PITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLS 279
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + + ++ ++ + L++L+L N YL ++F SLK+L+ L L+
Sbjct: 280 CDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERI 339
Query: 262 QLSVIVDNMF 271
++ I MF
Sbjct: 340 EIPNINTRMF 349
Score = 75.8 bits (178), Expect = 4e-13
Identities = 59/212 (27%), Positives = 91/212 (42%)
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
G + + P N+ L + + + S+ F L+ + L HN + + F GL N
Sbjct: 127 GDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L+L+HN I + F+ L L LIL +N I+ + RLF L L L + +N L
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L ++ + L ++ + + L LDL N L+ F LK
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKL 306
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
L+KL L N L + N F ++L L L R
Sbjct: 307 LQKLNLSSNPLMYLHKNQFESLKQLQSLDLER 338
Score = 50.0 bits (114), Expect = 2e-05
Identities = 47/197 (23%), Positives = 80/197 (40%), Gaps = 2/197 (1%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L +N L FI +LKK+ L N + I F L +L L+ N
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ N I R + F + +SL ++ N L + Q +P++
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGL-NSLFFLSMVNNYLEALPKQMCAQ-MPQL 259
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ V L ++ + + F + L LDLS N ++ L K LQ+L++S N L
Sbjct: 260 NWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMY 319
Query: 412 LSEQDLQRLEAIAEVNL 428
L + + L+ + ++L
Sbjct: 320 LHKNQFESLKQLQSLDL 336
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/103 (24%), Positives = 49/103 (47%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A L + + + + + +F +L VL+L+ N +T + F+ L L +L+L
Sbjct: 254 AQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLS 313
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLS 182
N + + F L L++L L +I + +R+F+ + LS
Sbjct: 314 SNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLS 356
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/278 (28%), Positives = 123/278 (44%), Gaps = 16/278 (5%)
Query: 10 EAAGTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNF 69
+AA CP C C D H VAC++ ++ +P D + + N
Sbjct: 33 QAATQRCPQACIC----DNSRRH---VACRYQNLTEVP------DAIPELTQRLDLQGNL 79
Query: 70 LTIGPIFT-QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
L + P Q P +L L + + V + + +F GL L +LNL N+L + +
Sbjct: 80 LKVIPAAAFQGVP--HLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 137
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
GL +L L L+ N +E + TF L +L TL LA+N + L + F+ L ++ L LS
Sbjct: 138 GLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 197
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L+ L PE + LR L+ + + L L+LG N Y ++ +
Sbjct: 198 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGL 257
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L++L LDG L + F LH L L N+
Sbjct: 258 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQ 295
Score = 55.2 bits (127), Expect = 6e-07
Identities = 50/210 (23%), Positives = 88/210 (41%), Gaps = 3/210 (1%)
Query: 220 TQIYHLVPRL-EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
T++ +P L + LDL NL K + + F + L L L ++ ++ + F L
Sbjct: 60 TEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 119
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPL 338
+L L+ N ++ N ++ TF + +L T+N + N L
Sbjct: 120 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFG-ALGALATLNLAHNALVY 178
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
A+ Q L + + L++ +L + L L L N+L P +LS+ +
Sbjct: 179 LP-AMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARG 237
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L RL++ HN L E+D L + E+ L
Sbjct: 238 LARLELGHNPLTYAGEEDGLALPGLRELLL 267
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/184 (25%), Positives = 75/184 (40%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + ++ PS+ + +F GL +L L+L H + + A GL L ++L N + +S
Sbjct: 436 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLS 495
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ L L L N+ + R L L L L DN + L P + LR
Sbjct: 496 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 555
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ ++ LE+L L N + + + L L +L+L GN L +
Sbjct: 556 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 615
Query: 268 DNMF 271
D F
Sbjct: 616 DGAF 619
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/210 (23%), Positives = 80/210 (38%), Gaps = 1/210 (0%)
Query: 128 RGLINLTEL-HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL 186
RG + T+L L NH + F L L +L L + I+ L + L +L + L
Sbjct: 427 RGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYL 486
Query: 187 SDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDE 246
SDN L L+ + L R ++ +P L L L +N L +
Sbjct: 487 SDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGD 546
Query: 247 FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI 306
+ L+ + L GN+++ + G REL L L RN+ +
Sbjct: 547 LGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQL 606
Query: 307 SHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
S N + F PV SL+ + + + L
Sbjct: 607 SGNPLRALRDGAFQPVGRSLQHLFLNSSGL 636
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/114 (28%), Positives = 48/114 (42%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ +R L + ++ + + + GL LR L+L HN L ++ L L L HN
Sbjct: 188 LRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNP 247
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
+ E L L+ L+L + L R F +L LDL N L L P
Sbjct: 248 LTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP 301
Score = 38.7 bits (86), Expect = 0.054
Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Query: 65 DRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVA 124
+R FL + + P +L LH+ ++ V + + LR + L+ N +T V
Sbjct: 511 ERNRFLQVPGAALRALP--SLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 568
Query: 125 DNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSI 183
L +LHLD N + ++ + L +L L L+ N + L F+ + + L
Sbjct: 569 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 628
Query: 184 LDLSDNPLTDLNPEVFKDI 202
L L+ + L + P F +
Sbjct: 629 LFLNSSGLEQICPGAFSGL 647
Score = 36.3 bits (80), Expect = 0.29
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 329 INFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRF 388
++ GN L + A Q +P + + L + ++ + + F L+ L+L+ N L
Sbjct: 73 LDLQGNLLKVIPAA-AFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLREL 131
Query: 389 PFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
P + L L+RL++ N L+ L L A+A +NL N
Sbjct: 132 PQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHN 174
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 89.8 bits (213), Expect = 2e-17
Identities = 67/252 (26%), Positives = 114/252 (45%), Gaps = 3/252 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ + + + SF GL +L+ L L HN L + F GL NL LHL+ N +
Sbjct: 119 LLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ S F L +L+ L++ N++ ++ FR LA L L L+ L +++ + +Q
Sbjct: 179 AIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQS 238
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L R+ + VP L+ LDL +N + + +F ++ LK+L L+ +
Sbjct: 239 LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEEL 298
Query: 265 VIVDNMFGRN-RELHVLTLSRN-RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
V +D N EL L ++ N R +++N + H QT
Sbjct: 299 VSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT-VES 357
Query: 323 VDSLKTINFSGN 334
+ +L+ + GN
Sbjct: 358 LPNLQEVGLHGN 369
Score = 75.8 bits (178), Expect = 4e-13
Identities = 76/302 (25%), Positives = 119/302 (39%), Gaps = 2/302 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N++ V L NLTEL L N F L L +L L NQ++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
L F LA L L L+ N L + P F + +L LLR I+++ + ++P L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E L +G N + F L L+ L L G L I D + L L+ N+
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
D++ N + R FA ++ LK + + ++ L LP
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQRVGPGDFANML-HLKELGLNNMEELVSIDKFALVNLP 310
Query: 350 EIHGVGLA-NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
E+ + + N L I F + + L L+ N LS + + LQ + + N
Sbjct: 311 ELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNP 370
Query: 409 LQ 410
++
Sbjct: 371 IR 372
Score = 74.5 bits (175), Expect = 9e-13
Identities = 70/275 (25%), Positives = 114/275 (41%), Gaps = 4/275 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL EL + ++ F L L L+L N LT + +F GL +L EL+L+HN +
Sbjct: 94 NLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQL 153
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+++ F L++L L L +N + + SR F ML L IL + N + + F+ +
Sbjct: 154 YRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLA 213
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+LR LR I+ + LE L +N + + LK L L+ N L
Sbjct: 214 NLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPL 273
Query: 264 SVIVDNMFGRNRELHVLTLSR-NRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAP 321
+ F L L L+ DI++N ++ H + F
Sbjct: 274 QRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHH 333
Query: 322 VVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGL 356
+ ++T+ + N L V + LP + VGL
Sbjct: 334 -LPQMETLMLNNNALSALHQQTV-ESLPNLQEVGL 366
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 4/209 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A +L+EL++ ++ + I +F GL NL L+L N L ++ + F L NL L +
Sbjct: 138 AGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIG 197
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N ++ + FR L +L++L+LA + + L L L DN L +
Sbjct: 198 GNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRAL 257
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF--ISLKRLKKLK 257
+ + L+ + L+R+ + + L+EL L N+ + ++ D+F ++L L KL
Sbjct: 258 EQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNMEELVSIDKFALVNLPELTKLD 316
Query: 258 LDGN-QLSVIVDNMFGRNRELHVLTLSRN 285
+ N +LS I F ++ L L+ N
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNN 345
Score = 63.3 bits (147), Expect = 2e-09
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 4/217 (1%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
FLT P PA + L + ++++ + Q L NL L+L+ N+ + +F
Sbjct: 59 FLTAVP----PALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH 114
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L LHL+ N + ++ +F L SL+ L L +NQ+ + R F L+ L L L+
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L ++ F+ + +L I + I + + L L L + ++
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L+ L NQL+ + + L L L++N
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Score = 59.3 bits (137), Expect = 4e-08
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 2/212 (0%)
Query: 217 RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE 276
R++ + L ELDL +N F +F +L +L L L+ NQL+ + D+ F
Sbjct: 83 RVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS 142
Query: 277 LHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
L L L+ N+ ++ N + + F ++ +L+ + GN +
Sbjct: 143 LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE-MLPNLEILMIGGNKV 201
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + + L + + LA ++L+EI + L +L N+L+R P + L +
Sbjct: 202 DAI-LDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQV 260
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L+ LD++ N LQ + D + + E+ L
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGL 292
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 89.8 bits (213), Expect = 2e-17
Identities = 67/252 (26%), Positives = 114/252 (45%), Gaps = 3/252 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ + + + SF GL +L+ L L HN L + F GL NL LHL+ N +
Sbjct: 119 LLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ S F L +L+ L++ N++ ++ FR LA L L L+ L +++ + +Q
Sbjct: 179 AIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQS 238
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L R+ + VP L+ LDL +N + + +F ++ LK+L L+ +
Sbjct: 239 LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEEL 298
Query: 265 VIVDNMFGRN-RELHVLTLSRN-RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
V +D N EL L ++ N R +++N + H QT
Sbjct: 299 VSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT-VES 357
Query: 323 VDSLKTINFSGN 334
+ +L+ + GN
Sbjct: 358 LPNLQEVGLHGN 369
Score = 75.8 bits (178), Expect = 4e-13
Identities = 76/302 (25%), Positives = 119/302 (39%), Gaps = 2/302 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N++ V L NLTEL L N F L L +L L NQ++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
L F LA L L L+ N L + P F + +L LLR I+++ + ++P L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E L +G N + F L L+ L L G L I D + L L+ N+
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
D++ N + R FA ++ LK + + ++ L LP
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQRVGPGDFANML-HLKELGLNNMEELVSIDKFALVNLP 310
Query: 350 EIHGVGLA-NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
E+ + + N L I F + + L L+ N LS + + LQ + + N
Sbjct: 311 ELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNP 370
Query: 409 LQ 410
++
Sbjct: 371 IR 372
Score = 74.5 bits (175), Expect = 9e-13
Identities = 70/275 (25%), Positives = 114/275 (41%), Gaps = 4/275 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL EL + ++ F L L L+L N LT + +F GL +L EL+L+HN +
Sbjct: 94 NLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQL 153
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+++ F L++L L L +N + + SR F ML L IL + N + + F+ +
Sbjct: 154 YRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLA 213
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+LR LR I+ + LE L +N + + LK L L+ N L
Sbjct: 214 NLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPL 273
Query: 264 SVIVDNMFGRNRELHVLTLSR-NRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAP 321
+ F L L L+ DI++N ++ H + F
Sbjct: 274 QRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHH 333
Query: 322 VVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGL 356
+ ++T+ + N L V + LP + VGL
Sbjct: 334 -LPQMETLMLNNNALSALHQQTV-ESLPNLQEVGL 366
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 4/209 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A +L+EL++ ++ + I +F GL NL L+L N L ++ + F L NL L +
Sbjct: 138 AGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIG 197
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N ++ + FR L +L++L+LA + + L L L DN L +
Sbjct: 198 GNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRAL 257
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF--ISLKRLKKLK 257
+ + L+ + L+R+ + + L+EL L N+ + ++ D+F ++L L KL
Sbjct: 258 EQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNMEELVSIDKFALVNLPELTKLD 316
Query: 258 LDGN-QLSVIVDNMFGRNRELHVLTLSRN 285
+ N +LS I F ++ L L+ N
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNN 345
Score = 63.3 bits (147), Expect = 2e-09
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 4/217 (1%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
FLT P PA + L + ++++ + Q L NL L+L+ N+ + +F
Sbjct: 59 FLTAVP----PALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH 114
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L LHL+ N + ++ +F L SL+ L L +NQ+ + R F L+ L L L+
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L ++ F+ + +L I + I + + L L L + ++
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L+ L NQL+ + + L L L++N
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Score = 59.3 bits (137), Expect = 4e-08
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 2/212 (0%)
Query: 217 RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE 276
R++ + L ELDL +N F +F +L +L L L+ NQL+ + D+ F
Sbjct: 83 RVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS 142
Query: 277 LHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
L L L+ N+ ++ N + + F ++ +L+ + GN +
Sbjct: 143 LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE-MLPNLEILMIGGNKV 201
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + + L + + LA ++L+EI + L +L N+L+R P + L +
Sbjct: 202 DAI-LDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQV 260
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L+ LD++ N LQ + D + + E+ L
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGL 292
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 89.8 bits (213), Expect = 2e-17
Identities = 67/252 (26%), Positives = 114/252 (45%), Gaps = 3/252 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L LH+ + + + SF GL +L+ L L HN L + F GL NL LHL+ N +
Sbjct: 119 LLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ S F L +L+ L++ N++ ++ FR LA L L L+ L +++ + +Q
Sbjct: 179 AIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQS 238
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L R+ + VP L+ LDL +N + + +F ++ LK+L L+ +
Sbjct: 239 LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEEL 298
Query: 265 VIVDNMFGRN-RELHVLTLSRN-RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
V +D N EL L ++ N R +++N + H QT
Sbjct: 299 VSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT-VES 357
Query: 323 VDSLKTINFSGN 334
+ +L+ + GN
Sbjct: 358 LPNLQEVGLHGN 369
Score = 75.8 bits (178), Expect = 4e-13
Identities = 76/302 (25%), Positives = 119/302 (39%), Gaps = 2/302 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L L N++ V L NLTEL L N F L L +L L NQ++
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
L F LA L L L+ N L + P F + +L LLR I+++ + ++P L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E L +G N + F L L+ L L G L I D + L L+ N+
Sbjct: 192 EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLAR 251
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
D++ N + R FA ++ LK + + ++ L LP
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQRVGPGDFANML-HLKELGLNNMEELVSIDKFALVNLP 310
Query: 350 EIHGVGLA-NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
E+ + + N L I F + + L L+ N LS + + LQ + + N
Sbjct: 311 ELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNP 370
Query: 409 LQ 410
++
Sbjct: 371 IR 372
Score = 74.5 bits (175), Expect = 9e-13
Identities = 70/275 (25%), Positives = 114/275 (41%), Gaps = 4/275 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL EL + ++ F L L L+L N LT + +F GL +L EL+L+HN +
Sbjct: 94 NLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQL 153
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+++ F L++L L L +N + + SR F ML L IL + N + + F+ +
Sbjct: 154 YRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLA 213
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+LR LR I+ + LE L +N + + LK L L+ N L
Sbjct: 214 NLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPL 273
Query: 264 SVIVDNMFGRNRELHVLTLSR-NRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAP 321
+ F L L L+ DI++N ++ H + F
Sbjct: 274 QRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHH 333
Query: 322 VVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGL 356
+ ++T+ + N L V + LP + VGL
Sbjct: 334 -LPQMETLMLNNNALSALHQQTV-ESLPNLQEVGL 366
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 4/209 (1%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A +L+EL++ ++ + I +F GL NL L+L N L ++ + F L NL L +
Sbjct: 138 AGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIG 197
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N ++ + FR L +L++L+LA + + L L L DN L +
Sbjct: 198 GNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRAL 257
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF--ISLKRLKKLK 257
+ + L+ + L+R+ + + L+EL L N+ + ++ D+F ++L L KL
Sbjct: 258 EQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNMEELVSIDKFALVNLPELTKLD 316
Query: 258 LDGN-QLSVIVDNMFGRNRELHVLTLSRN 285
+ N +LS I F ++ L L+ N
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNN 345
Score = 63.3 bits (147), Expect = 2e-09
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 4/217 (1%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFR 128
FLT P PA + L + ++++ + Q L NL L+L+ N+ + +F
Sbjct: 59 FLTAVP----PALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH 114
Query: 129 GLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L LHL+ N + ++ +F L SL+ L L +NQ+ + R F L+ L L L+
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 189 NPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI 248
N L ++ F+ + +L I + I + + L L L + ++
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 249 SLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L+ L NQL+ + + L L L++N
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKN 271
Score = 59.3 bits (137), Expect = 4e-08
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 2/212 (0%)
Query: 217 RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE 276
R++ + L ELDL +N F +F +L +L L L+ NQL+ + D+ F
Sbjct: 83 RVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS 142
Query: 277 LHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
L L L+ N+ ++ N + + F ++ +L+ + GN +
Sbjct: 143 LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE-MLPNLEILMIGGNKV 201
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + + L + + LA ++L+EI + L +L N+L+R P + L +
Sbjct: 202 DAI-LDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQV 260
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
L+ LD++ N LQ + D + + E+ L
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGL 292
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 89.0 bits (211), Expect = 4e-17
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L++ + + I SF L++L +L L+ N++ ++ F GL NL L L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ + F +L+ LK L L NN I ++ S F + L LDL + L+ ++ F+ +
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR C LR I + L+ +L+ELDL N + F L L+KL + +Q
Sbjct: 197 SNLRYLNLAMCNLREI-PNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+ VI N F + L + L+ N
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHN 277
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/225 (22%), Positives = 95/225 (42%), Gaps = 3/225 (1%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+L+L +N + + FK ++HL I + R +R I ++ + L L+L +N +
Sbjct: 80 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 139
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
+ F+ L +LK+L L N + I F R L L L +
Sbjct: 140 PNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNL 199
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
++ + + P++ L ++ SGN+L Q L + + + +Q
Sbjct: 200 RY-LNLAMCNLREIPNLTPLI-KLDELDLSGNHLSAIRPGS-FQGLMHLQKLWMIQSQIQ 256
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
I +N F + LV ++L+ N L+ P L + L+R+ + HN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/273 (24%), Positives = 117/273 (42%), Gaps = 22/273 (8%)
Query: 4 LVVYNTEAAGTICPDECTCTMTF-----------DLEEGHTTQVACQHGH---MRIIPVD 49
LVV A T CP C+C+ F ++ +G +T + H ++II V+
Sbjct: 36 LVVAGLVRAQT-CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVN 94
Query: 50 YMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNL 109
H+ I+ + + IG NL L + ++ + +I +F L L
Sbjct: 95 SFKHLRHLEILQLSRNHIRTIEIGAF----NGLANLNTLELFDNRLTTIPNGAFVYLSKL 150
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDH-NHIEQMSSETFRHLTSLKTLILANNQIS 168
+ L L +N + S+ + F + +L L L + +S F L++L+ L LA +
Sbjct: 151 KELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLR 210
Query: 169 TLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPR 228
+ + L KL LDLS N L+ + P F+ + HL+ + ++ I + +
Sbjct: 211 EIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQS 268
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L E++L N L D F L L+++ L N
Sbjct: 269 LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 49.6 bits (113), Expect = 3e-05
Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ N+ I + L L L+L+ N+L+++ +F+GL++L +L + + I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ + F +L SL + LA+N ++ L LF L L + L NP
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
Score = 47.6 bits (108), Expect = 1e-04
Identities = 53/270 (19%), Positives = 103/270 (38%), Gaps = 4/270 (1%)
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
R+ ++ I + + LE L L N + + F L L L+L N+L+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
I + F +L L L N D+ K + + + +
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L+ +N + NL EI + ++ ++ + L+ L I F HL L + +++
Sbjct: 199 LRYLNLAMCNL--REIPNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLL 445
+ L ++++HN L L L + ++L N W+C+ C +
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSW 314
Query: 446 YMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ ++T +C++P L+G G L
Sbjct: 315 WIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 89.0 bits (211), Expect = 4e-17
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L++ + + I SF L++L +L L+ N++ ++ F GL NL L L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ + F +L+ LK L L NN I ++ S F + L LDL + L+ ++ F+ +
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR C LR I + L+ +L+ELDL N + F L L+KL + +Q
Sbjct: 197 SNLRYLNLAMCNLREI-PNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+ VI N F + L + L+ N
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHN 277
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/225 (22%), Positives = 95/225 (42%), Gaps = 3/225 (1%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+L+L +N + + FK ++HL I + R +R I ++ + L L+L +N +
Sbjct: 80 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 139
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
+ F+ L +LK+L L N + I F R L L L +
Sbjct: 140 PNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNL 199
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
++ + + P++ L ++ SGN+L Q L + + + +Q
Sbjct: 200 RY-LNLAMCNLREIPNLTPLI-KLDELDLSGNHLSAIRPGS-FQGLMHLQKLWMIQSQIQ 256
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
I +N F + LV ++L+ N L+ P L + L+R+ + HN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/273 (24%), Positives = 117/273 (42%), Gaps = 22/273 (8%)
Query: 4 LVVYNTEAAGTICPDECTCTMTF-----------DLEEGHTTQVACQHGH---MRIIPVD 49
LVV A T CP C+C+ F ++ +G +T + H ++II V+
Sbjct: 36 LVVAGLVRAQT-CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVN 94
Query: 50 YMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNL 109
H+ I+ + + IG NL L + ++ + +I +F L L
Sbjct: 95 SFKHLRHLEILQLSRNHIRTIEIGAF----NGLANLNTLELFDNRLTTIPNGAFVYLSKL 150
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDH-NHIEQMSSETFRHLTSLKTLILANNQIS 168
+ L L +N + S+ + F + +L L L + +S F L++L+ L LA +
Sbjct: 151 KELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLR 210
Query: 169 TLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPR 228
+ + L KL LDLS N L+ + P F+ + HL+ + ++ I + +
Sbjct: 211 EIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQS 268
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L E++L N L D F L L+++ L N
Sbjct: 269 LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 49.6 bits (113), Expect = 3e-05
Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ N+ I + L L L+L+ N+L+++ +F+GL++L +L + + I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ + F +L SL + LA+N ++ L LF L L + L NP
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
Score = 47.6 bits (108), Expect = 1e-04
Identities = 53/270 (19%), Positives = 103/270 (38%), Gaps = 4/270 (1%)
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
R+ ++ I + + LE L L N + + F L L L+L N+L+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
I + F +L L L N D+ K + + + +
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L+ +N + NL EI + ++ ++ + L+ L I F HL L + +++
Sbjct: 199 LRYLNLAMCNL--REIPNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLL 445
+ L ++++HN L L L + ++L N W+C+ C +
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSW 314
Query: 446 YMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ ++T +C++P L+G G L
Sbjct: 315 WIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 89.0 bits (211), Expect = 4e-17
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L++ + + I SF L++L +L L+ N++ ++ F GL NL L L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ + F +L+ LK L L NN I ++ S F + L LDL + L+ ++ F+ +
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR C LR I + L+ +L+ELDL N + F L L+KL + +Q
Sbjct: 197 SNLRYLNLAMCNLREI-PNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+ VI N F + L + L+ N
Sbjct: 255 IQVIERNAFDNLQSLVEINLAHN 277
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/225 (22%), Positives = 95/225 (42%), Gaps = 3/225 (1%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+L+L +N + + FK ++HL I + R +R I ++ + L L+L +N +
Sbjct: 80 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 139
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
+ F+ L +LK+L L N + I F R L L L +
Sbjct: 140 PNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNL 199
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
++ + + P++ L ++ SGN+L Q L + + + +Q
Sbjct: 200 RY-LNLAMCNLREIPNLTPLI-KLDELDLSGNHLSAIRPGS-FQGLMHLQKLWMIQSQIQ 256
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
I +N F + LV ++L+ N L+ P L + L+R+ + HN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/273 (24%), Positives = 117/273 (42%), Gaps = 22/273 (8%)
Query: 4 LVVYNTEAAGTICPDECTCTMTF-----------DLEEGHTTQVACQHGH---MRIIPVD 49
LVV A T CP C+C+ F ++ +G +T + H ++II V+
Sbjct: 36 LVVAGLVRAQT-CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVN 94
Query: 50 YMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNL 109
H+ I+ + + IG NL L + ++ + +I +F L L
Sbjct: 95 SFKHLRHLEILQLSRNHIRTIEIGAF----NGLANLNTLELFDNRLTTIPNGAFVYLSKL 150
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDH-NHIEQMSSETFRHLTSLKTLILANNQIS 168
+ L L +N + S+ + F + +L L L + +S F L++L+ L LA +
Sbjct: 151 KELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLR 210
Query: 169 TLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPR 228
+ + L KL LDLS N L+ + P F+ + HL+ + ++ I + +
Sbjct: 211 EIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQS 268
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L E++L N L D F L L+++ L N
Sbjct: 269 LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 49.6 bits (113), Expect = 3e-05
Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ N+ I + L L L+L+ N+L+++ +F+GL++L +L + + I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ + F +L SL + LA+N ++ L LF L L + L NP
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
Score = 47.6 bits (108), Expect = 1e-04
Identities = 53/270 (19%), Positives = 103/270 (38%), Gaps = 4/270 (1%)
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
R+ ++ I + + LE L L N + + F L L L+L N+L+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
I + F +L L L N D+ K + + + +
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L+ +N + NL EI + ++ ++ + L+ L I F HL L + +++
Sbjct: 199 LRYLNLAMCNL--REIPNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLL 445
+ L ++++HN L L L + ++L N W+C+ C +
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSW 314
Query: 446 YMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ ++T +C++P L+G G L
Sbjct: 315 WIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 88.2 bits (209), Expect = 7e-17
Identities = 97/356 (27%), Positives = 154/356 (43%), Gaps = 40/356 (11%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
NL+E+++ N+ VPS+G S ++ L L HN + SV + ++L L L
Sbjct: 93 NLQEVYLNNNELTAVPSLGAAS----SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSL 148
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F H +K L LA N+I TL F L++ L L LS N +T L F
Sbjct: 149 NNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF 208
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
K +PRL +LDL N + + F L L+ LKL
Sbjct: 209 K-------------------------LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQ 243
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
N +S + D F ++HVL L N +S+N I R H + +
Sbjct: 244 RNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGW 303
Query: 320 APVVDSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVAL 378
+ L + S NNL L+E + L L + + L++ S+ I + F L L
Sbjct: 304 S-FCQKLHELVLSFNNLTRLDEES--LAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 379 DLSWNKLS---RFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
DL N++S S L +L + NK+++++++ LE + +NL N
Sbjct: 361 DLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGN 416
Score = 79.4 bits (187), Expect = 3e-14
Identities = 53/203 (26%), Positives = 97/203 (47%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L + +N+ + +FWGL + VL+L +N+L V + + GL L +LHL +N I
Sbjct: 236 SLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSI 295
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + + L L+L+ N ++ L L+ LS+L LS N ++ + FK ++
Sbjct: 296 ARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLR 355
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
LR+ + + + + L +L L N K + F L+ L+ L L G
Sbjct: 356 SLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGG 415
Query: 261 NQLSVIVDNMFGRNRELHVLTLS 283
N + + + F + + L L +S
Sbjct: 416 NAIRSVQFDAFVKMKNLKELHIS 438
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---FRGLINLTEL 136
A +L L + ++++ I + +F GL++LRVL+L HN ++ + D F GL +L++L
Sbjct: 328 AELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKL 387
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
L N I+ ++ F L L+ L L N I ++ F + L L +S +
Sbjct: 388 TLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSD 440
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 88.2 bits (209), Expect = 7e-17
Identities = 87/358 (24%), Positives = 143/358 (39%), Gaps = 9/358 (2%)
Query: 76 FTQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
F P L+EL ++ N+ + ++ + GL L+ L L N++TSV D+F GL+
Sbjct: 95 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 154
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L LD N + ++ +L +L+ L LA N+IS++ F L+ L +L L +N +
Sbjct: 155 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 214
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L+ F + +L L Q P L+EL N + F
Sbjct: 215 GLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSISVIPDGAFDGNPL 273
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L+ + L N LS + ++ F +LH L + R ++ KI
Sbjct: 274 LRTIHLYDNPLSFVGNSAFHNLSDLHSLVI-RGASMVQQFPNLTGTVHLESLTLTGTKIS 332
Query: 313 RFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYN 372
L+T++ S NN+ L EI L + +I + F
Sbjct: 333 SIP-NNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEI---SLQRNQIYQIKEGTFQGL 388
Query: 373 EHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMK 430
L LDLS N + + + + LD+S N+L + + L L + V K
Sbjct: 389 ISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFK 446
Score = 86.2 bits (204), Expect = 3e-16
Identities = 92/379 (24%), Positives = 153/379 (40%), Gaps = 11/379 (2%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L+++ NN+T + D F+ L EL L N + + + L LK L L NNQ+ T
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ S R L+ L L L N +T + + F+ + LR L + +P L
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
+ L L N + F +L L L L N++ + + F L L LS N
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQIL 348
S N I F L+TI+ N PL+ + L
Sbjct: 240 FPQAIKARPSLKELGFHS-NSISVIPDGAFDGN-PLLRTIHLYDN--PLSFVGNSAFHNL 295
Query: 349 PEIHGVGLANLSL-QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
++H + + S+ Q+ P T HL +L L+ K+S P L + K L+ LD+S+N
Sbjct: 296 SDLHSLVIRGASMVQQFPN--LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 353
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN-WHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLR 466
++ L A+ E++L +N + + + ++ + + I + +
Sbjct: 354 NIRDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFAT 411
Query: 467 LRGATFGSLSFEQLDPCPT 485
L T +SF +L PT
Sbjct: 412 LGPITNLDVSFNELTSFPT 430
Score = 62.9 bits (146), Expect = 3e-09
Identities = 75/347 (21%), Positives = 134/347 (38%), Gaps = 6/347 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L I +N+ + + +F L L L N+L+ + GL L L L +N ++ +
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE R L++L++L L N I+++ F L +L L L DN LT++ ++ L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ I + + L L L N + L+ F L L+ L L N L
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFP 241
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+ R L L N + N + F + D L
Sbjct: 242 QAIKAR-PSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSD-LH 299
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
++ G ++ + + + + L + IP N + L LDLS+N +
Sbjct: 300 SLVIRGASMVQQFPNLTGTV--HLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRD 357
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
P + L+ + + N++ + E Q L ++ ++L +N H
Sbjct: 358 LP--SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Score = 62.1 bits (144), Expect = 5e-09
Identities = 43/135 (31%), Positives = 67/135 (49%), Gaps = 5/135 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L L + + + SI + LR L+L++NN+ + +F G L E+ L N
Sbjct: 319 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQRNQ 376
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I Q+ TF+ L SL+ L L+ N I + SR F L ++ LD+S N LT E +
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGL 436
Query: 203 QHLRI---FKCRRCL 214
L++ FK + L
Sbjct: 437 NQLKLVGNFKLKEAL 451
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V + L +P+ + + ALD+S N +++ P FL+ L ++ N L +
Sbjct: 41 VDCSGKGLTAVPEGLSAFTQ---ALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 97
Query: 414 EQDLQRLEAIAEVNLMKN 431
+ L L+ + + L N
Sbjct: 98 PKALSGLKELKVLTLQNN 115
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 88.2 bits (209), Expect = 7e-17
Identities = 54/173 (31%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 88 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 147
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 148 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 207
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+L + R+ + +N + + +L+ELDLG N + L F LK L +
Sbjct: 208 SNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQ 260
Score = 76.2 bits (179), Expect = 3e-13
Identities = 53/180 (29%), Positives = 91/180 (50%), Gaps = 1/180 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 64 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 123
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 124 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 183
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L L L N+
Sbjct: 184 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 243
Score = 64.9 bits (151), Expect = 7e-10
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 1/176 (0%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F +L+ L L +N +TS+ FRGL +LT+L+L HN I + F L L+ LI+
Sbjct: 83 FKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLII 142
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDL-NPEVFKDIQHLRIFKCRRCLLRRINTQ 221
+N +S + F L L +L L +N LT L + + + + L + +
Sbjct: 143 EDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNL 202
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
+ L L + +N +L + F L++L +L L N++ + +F +EL
Sbjct: 203 TFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKEL 258
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/194 (22%), Positives = 75/194 (38%), Gaps = 1/194 (0%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L NL + L D F + L+KL L N+++ I F L L LS NR
Sbjct: 68 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLK 127
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
I N + R TF + +SL + N L + Q +P +
Sbjct: 128 PGVFEDLHRLEWLIIEDNHLSRISPPTFYGL-NSLILLVLMNNVLTRLPDKPLCQHMPRL 186
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H + L + + F +L L + NK++ + + L LD+ NK++
Sbjct: 187 HWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIEN 246
Query: 412 LSEQDLQRLEAIAE 425
L + L+ +++
Sbjct: 247 LPPLIFKDLKELSQ 260
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 62 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 121
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 88.2 bits (209), Expect = 7e-17
Identities = 97/356 (27%), Positives = 154/356 (43%), Gaps = 40/356 (11%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
NL+E+++ N+ VPS+G S ++ L L HN + SV + ++L L L
Sbjct: 93 NLQEVYLNNNELTAVPSLGAAS----SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSL 148
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F H +K L LA N+I TL F L++ L L LS N +T L F
Sbjct: 149 NNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF 208
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
K +PRL +LDL N + + F L L+ LKL
Sbjct: 209 K-------------------------LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQ 243
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF 319
N +S + D F ++HVL L N +S+N I R H + +
Sbjct: 244 RNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGW 303
Query: 320 APVVDSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVAL 378
+ L + S NNL L+E + L L + + L++ S+ I + F L L
Sbjct: 304 S-FCQKLHELVLSFNNLTRLDEES--LAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 379 DLSWNKLS---RFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
DL N++S S L +L + NK+++++++ LE + +NL N
Sbjct: 361 DLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGN 416
Score = 79.4 bits (187), Expect = 3e-14
Identities = 53/203 (26%), Positives = 97/203 (47%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L + +N+ + +FWGL + VL+L +N+L V + + GL L +LHL +N I
Sbjct: 236 SLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSI 295
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + + L L+L+ N ++ L L+ LS+L LS N ++ + FK ++
Sbjct: 296 ARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLR 355
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
LR+ + + + + L +L L N K + F L+ L+ L L G
Sbjct: 356 SLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGG 415
Query: 261 NQLSVIVDNMFGRNRELHVLTLS 283
N + + + F + + L L +S
Sbjct: 416 NAIRSVQFDAFVKMKNLKELHIS 438
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---FRGLINLTEL 136
A +L L + ++++ I + +F GL++LRVL+L HN ++ + D F GL +L++L
Sbjct: 328 AELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKL 387
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
L N I+ ++ F L L+ L L N I ++ F + L L +S +
Sbjct: 388 TLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSD 440
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 87.8 bits (208), Expect = 9e-17
Identities = 86/388 (22%), Positives = 167/388 (43%), Gaps = 13/388 (3%)
Query: 88 LHIVNSNVPSIGQFSFWG--LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
L V N + + ++G N+ +L+L HN + + A + L L L N I +
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLF-RMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ + +F + LK L L+NN+I+TL + F + + L ++ L+ N ++ + P++FK + H
Sbjct: 159 IKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L+ + +R ++ + + + L L + N L F L +++L+L+ N L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ R L L +S+N D+S+N++ R F +
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVG-LS 335
Query: 325 SLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEHLVALDLS 381
L+ +N G+N + V + L + + L N + E F L L L
Sbjct: 336 LLERLNL-GDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQ 394
Query: 382 WNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS 441
N++ K + L+ LD+++N + ++ E + + E+ L ++ CD C
Sbjct: 395 GNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCD-CHLK 452
Query: 442 NMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+L ++ ++ V C P L G
Sbjct: 453 WLLQWLVDNNFQHSVNV-SCAHPEWLAG 479
Score = 83.4 bits (197), Expect = 2e-15
Identities = 57/193 (29%), Positives = 96/193 (49%), Gaps = 3/193 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + + + + +F+GL N+ L L HNNLT V GL L +L++ N I
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E++S + + L L L+ NQ++ L F L+ L L+L DN +T + VF+ +
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+L+ R + ++ + + L +L L N K +T FI L+ L+ L L+
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 261 NQLSVIVDNMFGR 273
N + I +N F +
Sbjct: 420 NAIMSIQENAFSQ 432
Score = 66.5 bits (155), Expect = 2e-10
Identities = 76/319 (23%), Positives = 140/319 (43%), Gaps = 10/319 (3%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL- 130
I I Q F E ++SN+ S + S + L+ LNL++N +T++ A F L
Sbjct: 132 IPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLS 191
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L + L+ N + + + F+ L L+ L L N+I + F+ L L L + N
Sbjct: 192 SSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
++ L F + ++ + L R+N + + L++L + +N + ++ D +
Sbjct: 251 ISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFC 310
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+RL +L L NQL+ + ++ F L L L NR D+ +N+
Sbjct: 311 QRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNE 370
Query: 311 ID---RFHLQTFAPVVDSLKTINFSGNNL-PLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
I + FA + SL + GN + + + A + L + + L N ++ I +
Sbjct: 371 ISWAIEDASEAFAGLT-SLTKLILQGNQIKSITKKAFI--GLESLEHLDLNNNAIMSIQE 427
Query: 367 NFFTYNEHLVALDLSWNKL 385
N F+ HL L L+ + L
Sbjct: 428 NAFS-QTHLKELILNTSSL 445
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 87.8 bits (208), Expect = 9e-17
Identities = 86/388 (22%), Positives = 167/388 (43%), Gaps = 13/388 (3%)
Query: 88 LHIVNSNVPSIGQFSFWG--LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
L V N + + ++G N+ +L+L HN + + A + L L L N I +
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLF-RMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ + +F + LK L L+NN+I+TL + F + + L ++ L+ N ++ + P++FK + H
Sbjct: 159 IKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L+ + +R ++ + + + L L + N L F L +++L+L+ N L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ R L L +S+N D+S+N++ R F +
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVG-LS 335
Query: 325 SLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEHLVALDLS 381
L+ +N G+N + V + L + + L N + E F L L L
Sbjct: 336 LLERLNL-GDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQ 394
Query: 382 WNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS 441
N++ K + L+ LD+++N + ++ E + + E+ L ++ CD C
Sbjct: 395 GNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCD-CHLK 452
Query: 442 NMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+L ++ ++ V C P L G
Sbjct: 453 WLLQWLVDNNFQHSVNV-SCAHPEWLAG 479
Score = 83.4 bits (197), Expect = 2e-15
Identities = 57/193 (29%), Positives = 96/193 (49%), Gaps = 3/193 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + + + + +F+GL N+ L L HNNLT V GL L +L++ N I
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E++S + + L L L+ NQ++ L F L+ L L+L DN +T + VF+ +
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+L+ R + ++ + + L +L L N K +T FI L+ L+ L L+
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 261 NQLSVIVDNMFGR 273
N + I +N F +
Sbjct: 420 NAIMSIQENAFSQ 432
Score = 66.5 bits (155), Expect = 2e-10
Identities = 76/319 (23%), Positives = 140/319 (43%), Gaps = 10/319 (3%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL- 130
I I Q F E ++SN+ S + S + L+ LNL++N +T++ A F L
Sbjct: 132 IPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLS 191
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L + L+ N + + + F+ L L+ L L N+I + F+ L L L + N
Sbjct: 192 SSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
++ L F + ++ + L R+N + + L++L + +N + ++ D +
Sbjct: 251 ISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFC 310
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+RL +L L NQL+ + ++ F L L L NR D+ +N+
Sbjct: 311 QRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNE 370
Query: 311 ID---RFHLQTFAPVVDSLKTINFSGNNL-PLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
I + FA + SL + GN + + + A + L + + L N ++ I +
Sbjct: 371 ISWAIEDASEAFAGLT-SLTKLILQGNQIKSITKKAFI--GLESLEHLDLNNNAIMSIQE 427
Query: 367 NFFTYNEHLVALDLSWNKL 385
N F+ HL L L+ + L
Sbjct: 428 NAFS-QTHLKELILNTSSL 445
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 87.8 bits (208), Expect = 9e-17
Identities = 86/388 (22%), Positives = 167/388 (43%), Gaps = 13/388 (3%)
Query: 88 LHIVNSNVPSIGQFSFWG--LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
L V N + + ++G N+ +L+L HN + + A + L L L N I +
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLF-RMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ + +F + LK L L+NN+I+TL + F + + L ++ L+ N ++ + P++FK + H
Sbjct: 159 IKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L+ + +R ++ + + + L L + N L F L +++L+L+ N L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ R L L +S+N D+S+N++ R F +
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVG-LS 335
Query: 325 SLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEHLVALDLS 381
L+ +N G+N + V + L + + L N + E F L L L
Sbjct: 336 LLERLNL-GDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQ 394
Query: 382 WNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS 441
N++ K + L+ LD+++N + ++ E + + E+ L ++ CD C
Sbjct: 395 GNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCD-CHLK 452
Query: 442 NMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+L ++ ++ V C P L G
Sbjct: 453 WLLQWLVDNNFQHSVNV-SCAHPEWLAG 479
Score = 83.4 bits (197), Expect = 2e-15
Identities = 57/193 (29%), Positives = 96/193 (49%), Gaps = 3/193 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + + + + +F+GL N+ L L HNNLT V GL L +L++ N I
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E++S + + L L L+ NQ++ L F L+ L L+L DN +T + VF+ +
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+L+ R + ++ + + L +L L N K +T FI L+ L+ L L+
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 261 NQLSVIVDNMFGR 273
N + I +N F +
Sbjct: 420 NAIMSIQENAFSQ 432
Score = 66.5 bits (155), Expect = 2e-10
Identities = 76/319 (23%), Positives = 140/319 (43%), Gaps = 10/319 (3%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL- 130
I I Q F E ++SN+ S + S + L+ LNL++N +T++ A F L
Sbjct: 132 IPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLS 191
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L + L+ N + + + F+ L L+ L L N+I + F+ L L L + N
Sbjct: 192 SSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
++ L F + ++ + L R+N + + L++L + +N + ++ D +
Sbjct: 251 ISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFC 310
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+RL +L L NQL+ + ++ F L L L NR D+ +N+
Sbjct: 311 QRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNE 370
Query: 311 ID---RFHLQTFAPVVDSLKTINFSGNNL-PLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
I + FA + SL + GN + + + A + L + + L N ++ I +
Sbjct: 371 ISWAIEDASEAFAGLT-SLTKLILQGNQIKSITKKAFI--GLESLEHLDLNNNAIMSIQE 427
Query: 367 NFFTYNEHLVALDLSWNKL 385
N F+ HL L L+ + L
Sbjct: 428 NAFS-QTHLKELILNTSSL 445
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 87.8 bits (208), Expect = 9e-17
Identities = 86/388 (22%), Positives = 167/388 (43%), Gaps = 13/388 (3%)
Query: 88 LHIVNSNVPSIGQFSFWG--LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
L V N + + ++G N+ +L+L HN + + A + L L L N I +
Sbjct: 107 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 166
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLF-RMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ + +F + LK L L+NN+I+TL + F + + L ++ L+ N ++ + P++FK + H
Sbjct: 167 IKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 224
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L+ + +R ++ + + + L L + N L F L +++L+L+ N L+
Sbjct: 225 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 284
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ R L L +S+N D+S+N++ R F +
Sbjct: 285 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVG-LS 343
Query: 325 SLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEHLVALDLS 381
L+ +N G+N + V + L + + L N + E F L L L
Sbjct: 344 LLERLNL-GDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQ 402
Query: 382 WNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSAS 441
N++ K + L+ LD+++N + ++ E + + E+ L ++ CD C
Sbjct: 403 GNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCD-CHLK 460
Query: 442 NMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+L ++ ++ V C P L G
Sbjct: 461 WLLQWLVDNNFQHSVNV-SCAHPEWLAG 487
Score = 83.4 bits (197), Expect = 2e-15
Identities = 57/193 (29%), Positives = 96/193 (49%), Gaps = 3/193 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L + + + + +F+GL N+ L L HNNLT V GL L +L++ N I
Sbjct: 248 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 307
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E++S + + L L L+ NQ++ L F L+ L L+L DN +T + VF+ +
Sbjct: 308 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 367
Query: 204 HLRIFKCRRCLLR---RINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+L+ R + ++ + + L +L L N K +T FI L+ L+ L L+
Sbjct: 368 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 427
Query: 261 NQLSVIVDNMFGR 273
N + I +N F +
Sbjct: 428 NAIMSIQENAFSQ 440
Score = 66.5 bits (155), Expect = 2e-10
Identities = 76/319 (23%), Positives = 140/319 (43%), Gaps = 10/319 (3%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL- 130
I I Q F E ++SN+ S + S + L+ LNL++N +T++ A F L
Sbjct: 140 IPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLS 199
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L + L+ N + + + F+ L L+ L L N+I + F+ L L L + N
Sbjct: 200 SSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 258
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
++ L F + ++ + L R+N + + L++L + +N + ++ D +
Sbjct: 259 ISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFC 318
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+RL +L L NQL+ + ++ F L L L NR D+ +N+
Sbjct: 319 QRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNE 378
Query: 311 ID---RFHLQTFAPVVDSLKTINFSGNNL-PLNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
I + FA + SL + GN + + + A + L + + L N ++ I +
Sbjct: 379 ISWAIEDASEAFAGLT-SLTKLILQGNQIKSITKKAFI--GLESLEHLDLNNNAIMSIQE 435
Query: 367 NFFTYNEHLVALDLSWNKL 385
N F+ HL L L+ + L
Sbjct: 436 NAFS-QTHLKELILNTSSL 453
>BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine rich
transmembrane protein 1 protein.
Length = 674
Score = 87.0 bits (206), Expect = 2e-16
Identities = 75/262 (28%), Positives = 116/262 (44%), Gaps = 12/262 (4%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTL 282
+PR L EL L +N + + D + L+KL LD N +S I ++ F +++L +L L
Sbjct: 125 LPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFL 184
Query: 283 SRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA 342
SRN D N+I L F + +SL+ + GN L IA
Sbjct: 185 SRNHLSSIPSGLPHTLEELRLDD---NRISTIPLHAFKGL-NSLRRLVLDGNLLANQRIA 240
Query: 343 I-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQR 401
L + + L SL P N + HL L L N +S P+ L+K + L+R
Sbjct: 241 DDTFSRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELER 298
Query: 402 LDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKC 461
LD+S+N L TL L +A++ L N W C C+ + ++ +R L C
Sbjct: 299 LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCG-CNLMWLRDWVKARAAVVNVRGLMC 357
Query: 462 HSPLRLRGATFGSLSFEQLDPC 483
P ++RG ++ E +D C
Sbjct: 358 QGPEKVRGMAIKDITSE-MDEC 378
Score = 66.5 bits (155), Expect = 2e-10
Identities = 77/287 (26%), Positives = 121/287 (42%), Gaps = 28/287 (9%)
Query: 4 LVVYNTEAA-GTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAA 62
L+ + TE T CP C C F + C + IP D D D + +
Sbjct: 41 LIAFLTEVIDSTTCPSVCRCDNGF---------IYCNDRGLTSIPADIPD-DATTLYL-- 88
Query: 63 PPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV 122
+ N + I VN++ +++ ++ + +F ++LR L+L NN+ ++
Sbjct: 89 ---QNNQINNAGIPQDLKTKVNVQVIYLYEND---LDEFPINLPRSLRELHLQDNNVRTI 142
Query: 123 VADNFRGLINLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAK 180
D+ + L +LHLD N + +S E F LK L L+ N +S++ S L L +
Sbjct: 143 ARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEE 202
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHLVPRLEELDLGENL 238
L L DN ++ + FK + LR LL +RI + + L EL L N
Sbjct: 203 LR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRN- 258
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L+KL L N +S I N + REL L LS N
Sbjct: 259 -SLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNN 304
Score = 58.4 bits (135), Expect = 6e-08
Identities = 58/208 (27%), Positives = 97/208 (46%), Gaps = 13/208 (6%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT--SVVADNFRGLINLTELHLDHN 141
+LRELH+ ++NV +I + S + L L+L N+++ S+ D F L L L N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H+ + S H +L+ L L +N+IST+ F+ L L L L N L + + + F
Sbjct: 188 HLSSIPS-GLPH--TLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 200 KDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
+Q+L R L +N H L++L L +N ++ + ++ L++L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNLPSAH----LQKLYLQDNAISHIPYNTLAKMRELERLD 300
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L N L+ + +F L L L N
Sbjct: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 43.2 bits (97), Expect = 0.003
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F LQNL L+L N+L + + +L +L+L N I + T + L
Sbjct: 239 IADDTFSRLQNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMREL 296
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ L L+NN ++TL LF L L+ L L +NP
Sbjct: 297 ERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNP 329
>AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein.
Length = 674
Score = 87.0 bits (206), Expect = 2e-16
Identities = 75/262 (28%), Positives = 116/262 (44%), Gaps = 12/262 (4%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTL 282
+PR L EL L +N + + D + L+KL LD N +S I ++ F +++L +L L
Sbjct: 125 LPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFL 184
Query: 283 SRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA 342
SRN D N+I L F + +SL+ + GN L IA
Sbjct: 185 SRNHLSSIPSGLPHTLEELRLDD---NRISTIPLHAFKGL-NSLRRLVLDGNLLANQRIA 240
Query: 343 I-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQR 401
L + + L SL P N + HL L L N +S P+ L+K + L+R
Sbjct: 241 DDTFSRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELER 298
Query: 402 LDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKC 461
LD+S+N L TL L +A++ L N W C C+ + ++ +R L C
Sbjct: 299 LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCG-CNLMWLRDWVKARAAVVNVRGLMC 357
Query: 462 HSPLRLRGATFGSLSFEQLDPC 483
P ++RG ++ E +D C
Sbjct: 358 QGPEKVRGMAIKDITSE-MDEC 378
Score = 66.5 bits (155), Expect = 2e-10
Identities = 77/287 (26%), Positives = 121/287 (42%), Gaps = 28/287 (9%)
Query: 4 LVVYNTEAA-GTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAA 62
L+ + TE T CP C C F + C + IP D D D + +
Sbjct: 41 LIAFLTEVIDSTTCPSVCRCDNGF---------IYCNDRGLTSIPADIPD-DATTLYL-- 88
Query: 63 PPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV 122
+ N + I VN++ +++ ++ + +F ++LR L+L NN+ ++
Sbjct: 89 ---QNNQINNAGIPQDLKTKVNVQVIYLYEND---LDEFPINLPRSLRELHLQDNNVRTI 142
Query: 123 VADNFRGLINLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAK 180
D+ + L +LHLD N + +S E F LK L L+ N +S++ S L L +
Sbjct: 143 ARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEE 202
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHLVPRLEELDLGENL 238
L L DN ++ + FK + LR LL +RI + + L EL L N
Sbjct: 203 LR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRN- 258
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L+KL L N +S I N + REL L LS N
Sbjct: 259 -SLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNN 304
Score = 58.4 bits (135), Expect = 6e-08
Identities = 58/208 (27%), Positives = 97/208 (46%), Gaps = 13/208 (6%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT--SVVADNFRGLINLTELHLDHN 141
+LRELH+ ++NV +I + S + L L+L N+++ S+ D F L L L N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H+ + S H +L+ L L +N+IST+ F+ L L L L N L + + + F
Sbjct: 188 HLSSIPS-GLPH--TLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 200 KDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
+Q+L R L +N H L++L L +N ++ + ++ L++L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNLPSAH----LQKLYLQDNAISHIPYNTLAKMRELERLD 300
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L N L+ + +F L L L N
Sbjct: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 43.2 bits (97), Expect = 0.003
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F LQNL L+L N+L + + +L +L+L N I + T + L
Sbjct: 239 IADDTFSRLQNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMREL 296
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ L L+NN ++TL LF L L+ L L +NP
Sbjct: 297 ERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNP 329
>AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat
transmembrane protein FLRT1 protein.
Length = 674
Score = 87.0 bits (206), Expect = 2e-16
Identities = 75/262 (28%), Positives = 116/262 (44%), Gaps = 12/262 (4%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTL 282
+PR L EL L +N + + D + L+KL LD N +S I ++ F +++L +L L
Sbjct: 125 LPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFL 184
Query: 283 SRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA 342
SRN D N+I L F + +SL+ + GN L IA
Sbjct: 185 SRNHLSSIPSGLPHTLEELRLDD---NRISTIPLHAFKGL-NSLRRLVLDGNLLANQRIA 240
Query: 343 I-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQR 401
L + + L SL P N + HL L L N +S P+ L+K + L+R
Sbjct: 241 DDTFSRLQNLTELSLVRNSLAAPPLNL--PSAHLQKLYLQDNAISHIPYNTLAKMRELER 298
Query: 402 LDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKC 461
LD+S+N L TL L +A++ L N W C C+ + ++ +R L C
Sbjct: 299 LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCG-CNLMWLRDWVKARAAVVNVRGLMC 357
Query: 462 HSPLRLRGATFGSLSFEQLDPC 483
P ++RG ++ E +D C
Sbjct: 358 QGPEKVRGMAIKDITSE-MDEC 378
Score = 66.5 bits (155), Expect = 2e-10
Identities = 77/287 (26%), Positives = 121/287 (42%), Gaps = 28/287 (9%)
Query: 4 LVVYNTEAA-GTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAA 62
L+ + TE T CP C C F + C + IP D D D + +
Sbjct: 41 LIAFLTEVIDSTTCPSVCRCDNGF---------IYCNDRGLTSIPADIPD-DATTLYL-- 88
Query: 63 PPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV 122
+ N + I VN++ +++ ++ + +F ++LR L+L NN+ ++
Sbjct: 89 ---QNNQINNAGIPQDLKTKVNVQVIYLYEND---LDEFPINLPRSLRELHLQDNNVRTI 142
Query: 123 VADNFRGLINLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAK 180
D+ + L +LHLD N + +S E F LK L L+ N +S++ S L L +
Sbjct: 143 ARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEE 202
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHLVPRLEELDLGENL 238
L L DN ++ + FK + LR LL +RI + + L EL L N
Sbjct: 203 LR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRN- 258
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L+KL L N +S I N + REL L LS N
Sbjct: 259 -SLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNN 304
Score = 58.4 bits (135), Expect = 6e-08
Identities = 58/208 (27%), Positives = 97/208 (46%), Gaps = 13/208 (6%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT--SVVADNFRGLINLTELHLDHN 141
+LRELH+ ++NV +I + S + L L+L N+++ S+ D F L L L N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H+ + S H +L+ L L +N+IST+ F+ L L L L N L + + + F
Sbjct: 188 HLSSIPS-GLPH--TLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 200 KDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
+Q+L R L +N H L++L L +N ++ + ++ L++L
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLNLPSAH----LQKLYLQDNAISHIPYNTLAKMRELERLD 300
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L N L+ + +F L L L N
Sbjct: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 43.2 bits (97), Expect = 0.003
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F LQNL L+L N+L + + +L +L+L N I + T + L
Sbjct: 239 IADDTFSRLQNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMREL 296
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ L L+NN ++TL LF L L+ L L +NP
Sbjct: 297 ERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNP 329
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 86.6 bits (205), Expect = 2e-16
Identities = 85/340 (25%), Positives = 150/340 (44%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ L +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL +N +++ F L L+ L L+G
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 294 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 349
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 350 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 409 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 447
Score = 80.6 bits (190), Expect = 1e-14
Identities = 77/321 (23%), Positives = 130/321 (40%), Gaps = 8/321 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNN-LDEF 249
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
N I F + + L+T+ +G + + E L +
Sbjct: 250 PTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPE-LRTLTLNGAS-QITEFP-DLTGTANL 306
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFP-FKLLSKTKFLQRLDISHNKLQ 410
+ L + +PQ +L LDLS+N L P F + K LQ++D+ HN++
Sbjct: 307 ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQK---LQKIDLRHNEIY 363
Query: 411 TLSEQDLQRLEAIAEVNLMKN 431
+ Q+L ++ +NL N
Sbjct: 364 EIKVDTFQQLLSLRSLNLAWN 384
Score = 64.5 bits (150), Expect = 9e-10
Identities = 76/328 (23%), Positives = 128/328 (39%), Gaps = 10/328 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+ L L L N LT + F GL +L L L +N + + +E ++L SL++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
IS + F L L L L DN LT++ + F+ + L+ + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLTLS 283
+ L L L N L F L L+ L L+ N L +ELH
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
Query: 284 RNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI 343
S +I F T ++SL ++LP
Sbjct: 269 IQFVGRSAFQHLPELRTLTLNGAS--QITEFPDLTGTANLESLTLTGAQISSLP----QT 322
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
V LP + + L+ L+++P F+ + L +DL N++ + L+ L+
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLN 380
Query: 404 ISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
++ NK+ + L ++ +++L N
Sbjct: 381 LAWNKIAIIHPNAFSTLPSLIKLDLSSN 408
Score = 34.7 bits (76), Expect = 0.88
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N L + SL+ L++L+L GN L+ I F L VL L N+
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ ++D H+ P FSG L +
Sbjct: 131 TEALQNLRS-----LQSLRLDANHISYVPPSC-------FSG--------------LHSL 164
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ L + +L EIP F L A+ L+ NK+ P L L + +N++ +
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
L ++ L ++ ++L NN
Sbjct: 225 LGKKCFDGLHSLETLDLNYNN 245
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 86.6 bits (205), Expect = 2e-16
Identities = 85/340 (25%), Positives = 150/340 (44%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ L +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL +N +++ F L L+ L L+G
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 294 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 349
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 350 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 409 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 447
Score = 80.6 bits (190), Expect = 1e-14
Identities = 77/321 (23%), Positives = 130/321 (40%), Gaps = 8/321 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNN-LDEF 249
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
N I F + + L+T+ +G + + E L +
Sbjct: 250 PTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPE-LRTLTLNGAS-QITEFP-DLTGTANL 306
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFP-FKLLSKTKFLQRLDISHNKLQ 410
+ L + +PQ +L LDLS+N L P F + K LQ++D+ HN++
Sbjct: 307 ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQK---LQKIDLRHNEIY 363
Query: 411 TLSEQDLQRLEAIAEVNLMKN 431
+ Q+L ++ +NL N
Sbjct: 364 EIKVDTFQQLLSLRSLNLAWN 384
Score = 64.5 bits (150), Expect = 9e-10
Identities = 76/328 (23%), Positives = 128/328 (39%), Gaps = 10/328 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+ L L L N LT + F GL +L L L +N + + +E ++L SL++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
IS + F L L L L DN LT++ + F+ + L+ + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLTLS 283
+ L L L N L F L L+ L L+ N L +ELH
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
Query: 284 RNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI 343
S +I F T ++SL ++LP
Sbjct: 269 IQFVGRSAFQHLPELRTLTLNGAS--QITEFPDLTGTANLESLTLTGAQISSLP----QT 322
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
V LP + + L+ L+++P F+ + L +DL N++ + L+ L+
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLN 380
Query: 404 ISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
++ NK+ + L ++ +++L N
Sbjct: 381 LAWNKIAIIHPNAFSTLPSLIKLDLSSN 408
Score = 34.7 bits (76), Expect = 0.88
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N L + SL+ L++L+L GN L+ I F L VL L N+
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ ++D H+ P FSG L +
Sbjct: 131 TEALQNLRS-----LQSLRLDANHISYVPPSC-------FSG--------------LHSL 164
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ L + +L EIP F L A+ L+ NK+ P L L + +N++ +
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
L ++ L ++ ++L NN
Sbjct: 225 LGKKCFDGLHSLETLDLNYNN 245
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 86.6 bits (205), Expect = 2e-16
Identities = 80/329 (24%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + I + W L +L+ L L N ++ V +F GL +L L LD N +
Sbjct: 63 SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL 122
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +L +L+ + LA N+IS + F+ L L +L L +N + L F+ +
Sbjct: 123 TEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLH 182
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L+ I L RL+EL N K + F+ L+ + N +
Sbjct: 183 NLETLDLNYNKLQEFPVAIRTL-GRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI 241
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F +LH L+L+ ++ I R +
Sbjct: 242 QFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPSGMCQQL 299
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ + S N + E L ++ +GL + + EI + F+ L ALDLSWN
Sbjct: 300 PRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
+ + S L +LD++ N+L TL
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTL 385
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/321 (24%), Positives = 136/321 (42%), Gaps = 10/321 (3%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L L L L N ++ + F+ + LR L I + + +P L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
L N ++ F +L L L L N++ + + F L L L+ N+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK-LQEFP 198
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPEI 351
+N I + F L+TI+F N P+ + Q LP++
Sbjct: 199 VAIRTLGRLQELGFHNNNIKAIPEKAFMG-NPLLQTIHFYDN--PIQFVGRSAFQYLPKL 255
Query: 352 HGVGL-ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQ 410
H + L + +QE P T + ++ L + +L P + + L+ L++SHN+++
Sbjct: 256 HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRL--LPSGMCQQLPRLRVLELSHNQIE 313
Query: 411 TLSEQDLQRLEAIAEVNLMKN 431
L L R + + E+ L N
Sbjct: 314 EL--PSLHRCQKLEEIGLQHN 332
Score = 69.7 bits (163), Expect = 3e-11
Identities = 77/307 (25%), Positives = 129/307 (42%), Gaps = 8/307 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + + + SF GL +LR L L N LT + L L + L N I
Sbjct: 87 SLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRI 146
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++LTSL L L NN+I L + F L L LDL+ N L + P + +
Sbjct: 147 SHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLG 205
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ ++ I + + P L+ + +N +++ F L +L L L+G
Sbjct: 206 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD 265
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L +LTL+R ++SHN+I+
Sbjct: 266 IQEFPDLKGTT-SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL---PSLHRC 321
Query: 324 DSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L+ I N + EI A L + + L+ +++ I F+ LV LDL+
Sbjct: 322 QKLEEIGLQHNRIW--EIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTD 379
Query: 383 NKLSRFP 389
N+L+ P
Sbjct: 380 NQLTTLP 386
Score = 69.3 bits (162), Expect = 3e-11
Identities = 79/356 (22%), Positives = 148/356 (41%), Gaps = 12/356 (3%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q + ++ R+L + +N+ + F L+ L L L+ N+L+ + F GL +L L
Sbjct: 11 QVSIIISARDLSM--NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILM 68
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L +N + + +E L SL++L L N IS + R F L+ L L L DN LT++
Sbjct: 69 LQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVR 128
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ L+ + I + + L L L N ++L + F L L+ L
Sbjct: 129 ALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLD 188
Query: 258 LDGNQLS--VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L+ N+L + GR +E L N N I +F
Sbjct: 189 LNYNKLQEFPVAIRTLGRLQE---LGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI-QFV 244
Query: 316 LQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHL 375
++ + L T++ +G + + E L+ + + L ++ +P L
Sbjct: 245 GRSAFQYLPKLHTLSLNG-AMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+LS N++ P L + + L+ + + HN++ + +L ++ ++L N
Sbjct: 303 RVLELSHNQIEELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 299 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 398
Score = 48.4 bits (110), Expect = 7e-05
Identities = 49/207 (23%), Positives = 84/207 (40%), Gaps = 5/207 (2%)
Query: 82 FVNLRELHIVNSNVPSIGQF--SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
F L L ++ N + +F + L L+ L +NN+ ++ F G L +H
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I+ + F++L L TL L N + + L IL L+ + L +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMC 296
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ + LR+ + + + + H +LEE+ L N + +D F L L+ L L
Sbjct: 297 QQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS 354
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRNR 286
N + I F L L L+ N+
Sbjct: 355 WNAIRSIHPEAFSTLHSLVKLDLTDNQ 381
Score = 47.6 bits (108), Expect = 1e-04
Identities = 69/313 (22%), Positives = 116/313 (37%), Gaps = 9/313 (2%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+S DLS N LT+L P +F ++ L + L I Q + + L+ L L N
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 241 YLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXX 300
+ ++ L L+ L+LD N +S++ + F L L L N
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 301 XXXXDISHNKIDRFHLQTFA-PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
++ N+I H+ +A + SL ++ N + + + L + + L
Sbjct: 136 LQAMTLALNRIS--HIPDYAFQNLTSLVVLHLHNNRIQ-HLGTHSFEGLHNLETLDLNYN 192
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
LQE P T L L N + P K LQ + N +Q + Q
Sbjct: 193 KLQEFPVAIRTLG-RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQY 251
Query: 420 LEAIAEVNL--MKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
L + ++L + + L +T T + IR+L +L LS
Sbjct: 252 LPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLT--RAGIRLLPSGMCQQLPRLRVLELSH 309
Query: 478 EQLDPCPTTHEAQ 490
Q++ P+ H Q
Sbjct: 310 NQIEELPSLHRCQ 322
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 86.6 bits (205), Expect = 2e-16
Identities = 77/275 (28%), Positives = 116/275 (42%), Gaps = 4/275 (1%)
Query: 159 TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
T L N I+ + + F L +L LDL N + L+P+ F+ + L LL+ +
Sbjct: 63 TYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQAL 122
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+ +L L N L+ F L+ L KL+LDGN L + D +F L
Sbjct: 123 APGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLL 182
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVDSLKTINFSGNNL 336
L L NR ++S N++ H TFAP + SL ++ S N+L
Sbjct: 183 YLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAP-LRSLSSLILSANSL 241
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + Q LP + + L L + F E L L L N+LS+ P LL
Sbjct: 242 Q-HLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPL 300
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ LD+S N+L L L + E++L N
Sbjct: 301 HSLEALDLSGNELSALHPATFGHLGRLRELSLRNN 335
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 2/203 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L EL++ N+ + ++ + L+ LR+L N ++ + +F GL +L +L LD N +
Sbjct: 109 LEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALG 168
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
+ F L +L L L +N+I L F L KL L+LS N L + F +
Sbjct: 169 ALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPL 228
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+ L L+ + +I+ +PRL L L N +L + F L+ L++L+L+GN+
Sbjct: 229 RSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNR 288
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
LS + + L L LS N
Sbjct: 289 LSQLPTALLEPLHSLEALDLSGN 311
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/208 (31%), Positives = 94/208 (45%), Gaps = 2/208 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP LR L+ + + + + SF GL++L L L N L ++ F L NL LHL+
Sbjct: 128 APLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLE 187
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQI--STLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
N I + F L L+ L L+ N++ S + F L LS L LS N L L P
Sbjct: 188 SNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPR 247
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
+F+ + L + R L + + + + L EL L N L + L L+ L
Sbjct: 248 IFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALD 307
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L GN+LS + FG L L+L N
Sbjct: 308 LSGNELSALHPATFGHLGRLRELSLRNN 335
Score = 82.6 bits (195), Expect = 3e-15
Identities = 63/204 (30%), Positives = 99/204 (48%), Gaps = 2/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L +L + + + ++ F L NL L+L N + + + F L L L+L N +
Sbjct: 156 SLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANEL 215
Query: 144 EQM--SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
+ + TF L SL +LIL+ N + L R+F+ L +L +L L N LT L PE F
Sbjct: 216 QPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWG 275
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
++ LR + L ++ T + + LE LDL N L F L RL++L L N
Sbjct: 276 LEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNN 335
Query: 262 QLSVIVDNMFGRNRELHVLTLSRN 285
LS + ++F + L+ L L N
Sbjct: 336 ALSALSGDIFAASPALYRLDLDGN 359
Score = 78.2 bits (184), Expect = 7e-14
Identities = 88/349 (25%), Positives = 134/349 (38%), Gaps = 11/349 (3%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N I +++ F L L+ L L NQI +L + F L++L L L +N L L P
Sbjct: 66 LGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPG 125
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ LRI + R++ + + L +L L N L F L L L
Sbjct: 126 TLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLH 185
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI--SHNKIDRFH 315
L+ N++ + N F + +L L LS N + S N +
Sbjct: 186 LESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLG 245
Query: 316 LQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNE 373
+ F + L ++ GN L E L+ L E+ L L ++P
Sbjct: 246 PRIFQHL-PRLGLLSLRGNQLTHLAPEAFWGLEALRELR---LEGNRLSQLPTALLEPLH 301
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
L ALDLS N+LS L+ L + +N L LS A+ ++L N W
Sbjct: 302 SLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGW 361
Query: 434 HCDQCSASNMLLYMTTTVLNSTIRV--LKCHSPLRLRGATFGSLSFEQL 480
CD C + +M + ++C P LRG L +QL
Sbjct: 362 TCD-CRLRGLKRWMGDWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQQL 409
Score = 75.8 bits (178), Expect = 4e-13
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 4/297 (1%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L N +T++ A +F L L L L +N I + +TF L+ L+ L L NN + L
Sbjct: 65 SLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAP 124
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L KL IL + N ++ L+ F+ ++ L + L + ++ + L L
Sbjct: 125 GTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYL 184
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDN--MFGRNRELHVLTLSRNRXXXX 290
L N ++L + F L +L+ L L N+L + + F R L L LS N
Sbjct: 185 HLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHL 244
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPE 350
+ N++ + F +++L+ + GN L A+ L+ L
Sbjct: 245 GPRIFQHLPRLGLLSLRGNQLTHLAPEAFWG-LEALRELRLEGNRLSQLPTAL-LEPLHS 302
Query: 351 IHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+ + L+ L + F + L L L N LS + + + L RLD+ N
Sbjct: 303 LEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
Score = 73.3 bits (172), Expect = 2e-12
Identities = 72/291 (24%), Positives = 116/291 (39%), Gaps = 4/291 (1%)
Query: 95 VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL 154
+ +I F F L LR L+L +N + S+ F L L EL+L +N ++ ++ T L
Sbjct: 71 ITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPL 130
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
L+ L N+IS L F L L L L N L L VF + +L
Sbjct: 131 RKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 190
Query: 215 LRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
+R + + + +L L+L N + + F L+ L L L N L + +F
Sbjct: 191 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQ 250
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
L +L+L N+ + N++ + P + SL+ ++ S
Sbjct: 251 HLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEP-LHSLEALDLS 309
Query: 333 GNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
GN L A L + + L N +L + + F + L LDL N
Sbjct: 310 GNELSALHPA-TFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/121 (32%), Positives = 54/121 (44%), Gaps = 2/121 (1%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
+GP Q P + L L + + + +FWGL+ LR L L N L+ + L
Sbjct: 244 LGPRIFQHLPRLGLLSLR--GNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLH 301
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+L L L N + + TF HL L+ L L NN +S L +F L LDL N
Sbjct: 302 SLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGW 361
Query: 192 T 192
T
Sbjct: 362 T 362
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 86.6 bits (205), Expect = 2e-16
Identities = 80/329 (24%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + I + W L +L+ L L N ++ V +F GL +L L LD N +
Sbjct: 63 SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL 122
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +L +L+ + LA N+IS + F+ L L +L L +N + L F+ +
Sbjct: 123 TEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLH 182
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L+ I L RL+EL N K + F+ L+ + N +
Sbjct: 183 NLETLDLNYNKLQEFPVAIRTL-GRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI 241
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F +LH L+L+ ++ I R +
Sbjct: 242 QFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPSGMCQQL 299
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ + S N + E L ++ +GL + + EI + F+ L ALDLSWN
Sbjct: 300 PRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
+ + S L +LD++ N+L TL
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTL 385
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/321 (24%), Positives = 136/321 (42%), Gaps = 10/321 (3%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L L L L N ++ + F+ + LR L I + + +P L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
L N ++ F +L L L L N++ + + F L L L+ N+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK-LQEFP 198
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPEI 351
+N I + F L+TI+F N P+ + Q LP++
Sbjct: 199 VAIRTLGRLQELGFHNNNIKAIPEKAFMG-NPLLQTIHFYDN--PIQFVGRSAFQYLPKL 255
Query: 352 HGVGL-ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQ 410
H + L + +QE P T + ++ L + +L P + + L+ L++SHN+++
Sbjct: 256 HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRL--LPSGMCQQLPRLRVLELSHNQIE 313
Query: 411 TLSEQDLQRLEAIAEVNLMKN 431
L L R + + E+ L N
Sbjct: 314 EL--PSLHRCQKLEEIGLQHN 332
Score = 69.7 bits (163), Expect = 3e-11
Identities = 77/307 (25%), Positives = 129/307 (42%), Gaps = 8/307 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + + + SF GL +LR L L N LT + L L + L N I
Sbjct: 87 SLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRI 146
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++LTSL L L NN+I L + F L L LDL+ N L + P + +
Sbjct: 147 SHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLG 205
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ ++ I + + P L+ + +N +++ F L +L L L+G
Sbjct: 206 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD 265
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L +LTL+R ++SHN+I+
Sbjct: 266 IQEFPDLKGTT-SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL---PSLHRC 321
Query: 324 DSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L+ I N + EI A L + + L+ +++ I F+ LV LDL+
Sbjct: 322 QKLEEIGLQHNRIW--EIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTD 379
Query: 383 NKLSRFP 389
N+L+ P
Sbjct: 380 NQLTTLP 386
Score = 69.3 bits (162), Expect = 3e-11
Identities = 79/356 (22%), Positives = 148/356 (41%), Gaps = 12/356 (3%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q + ++ R+L + +N+ + F L+ L L L+ N+L+ + F GL +L L
Sbjct: 11 QVSIIISARDLSM--NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILM 68
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L +N + + +E L SL++L L N IS + R F L+ L L L DN LT++
Sbjct: 69 LQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVR 128
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ L+ + I + + L L L N ++L + F L L+ L
Sbjct: 129 ALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLD 188
Query: 258 LDGNQLS--VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L+ N+L + GR +E L N N I +F
Sbjct: 189 LNYNKLQEFPVAIRTLGRLQE---LGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI-QFV 244
Query: 316 LQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHL 375
++ + L T++ +G + + E L+ + + L ++ +P L
Sbjct: 245 GRSAFQYLPKLHTLSLNG-AMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+LS N++ P L + + L+ + + HN++ + +L ++ ++L N
Sbjct: 303 RVLELSHNQIEELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 299 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 398
Score = 48.4 bits (110), Expect = 7e-05
Identities = 49/207 (23%), Positives = 84/207 (40%), Gaps = 5/207 (2%)
Query: 82 FVNLRELHIVNSNVPSIGQF--SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
F L L ++ N + +F + L L+ L +NN+ ++ F G L +H
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I+ + F++L L TL L N + + L IL L+ + L +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMC 296
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ + LR+ + + + + H +LEE+ L N + +D F L L+ L L
Sbjct: 297 QQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS 354
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRNR 286
N + I F L L L+ N+
Sbjct: 355 WNAIRSIHPEAFSTLHSLVKLDLTDNQ 381
Score = 47.6 bits (108), Expect = 1e-04
Identities = 69/313 (22%), Positives = 116/313 (37%), Gaps = 9/313 (2%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+S DLS N LT+L P +F ++ L + L I Q + + L+ L L N
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 241 YLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXX 300
+ ++ L L+ L+LD N +S++ + F L L L N
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 301 XXXXDISHNKIDRFHLQTFA-PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
++ N+I H+ +A + SL ++ N + + + L + + L
Sbjct: 136 LQAMTLALNRIS--HIPDYAFQNLTSLVVLHLHNNRIQ-HLGTHSFEGLHNLETLDLNYN 192
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
LQE P T L L N + P K LQ + N +Q + Q
Sbjct: 193 KLQEFPVAIRTLG-RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQY 251
Query: 420 LEAIAEVNL--MKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
L + ++L + + L +T T + IR+L +L LS
Sbjct: 252 LPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLT--RAGIRLLPSGMCQQLPRLRVLELSH 309
Query: 478 EQLDPCPTTHEAQ 490
Q++ P+ H Q
Sbjct: 310 NQIEELPSLHRCQ 322
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 86.6 bits (205), Expect = 2e-16
Identities = 80/329 (24%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + I + W L +L+ L L N ++ V +F GL +L L LD N +
Sbjct: 63 SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL 122
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +L +L+ + LA N+IS + F+ L L +L L +N + L F+ +
Sbjct: 123 TEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLH 182
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L+ I L RL+EL N K + F+ L+ + N +
Sbjct: 183 NLETLDLNYNKLQEFPVAIRTL-GRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI 241
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F +LH L+L+ ++ I R +
Sbjct: 242 QFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPSGMCQQL 299
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ + S N + E L ++ +GL + + EI + F+ L ALDLSWN
Sbjct: 300 PRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
+ + S L +LD++ N+L TL
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTL 385
Score = 80.6 bits (190), Expect = 1e-14
Identities = 80/321 (24%), Positives = 136/321 (42%), Gaps = 10/321 (3%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L L L L N ++ + F+ + LR L I + + +P L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
L N ++ F +L L L L N++ + + F L L L+ N+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK-LQEFP 198
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPEI 351
+N I + F L+TI+F N P+ + Q LP++
Sbjct: 199 VAIRTLGRLQELGFHNNNIKAIPEKAFMG-NPLLQTIHFYDN--PIQFVGRSAFQYLPKL 255
Query: 352 HGVGL-ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQ 410
H + L + +QE P T + ++ L + +L P + + L+ L++SHN+++
Sbjct: 256 HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRL--LPSGMCQQLPRLRVLELSHNQIE 313
Query: 411 TLSEQDLQRLEAIAEVNLMKN 431
L L R + + E+ L N
Sbjct: 314 EL--PSLHRCQKLEEIGLQHN 332
Score = 69.7 bits (163), Expect = 3e-11
Identities = 77/307 (25%), Positives = 129/307 (42%), Gaps = 8/307 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + + + SF GL +LR L L N LT + L L + L N I
Sbjct: 87 SLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRI 146
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++LTSL L L NN+I L + F L L LDL+ N L + P + +
Sbjct: 147 SHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLG 205
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ ++ I + + P L+ + +N +++ F L +L L L+G
Sbjct: 206 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD 265
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L +LTL+R ++SHN+I+
Sbjct: 266 IQEFPDLKGTT-SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL---PSLHRC 321
Query: 324 DSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L+ I N + EI A L + + L+ +++ I F+ LV LDL+
Sbjct: 322 QKLEEIGLQHNRIW--EIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTD 379
Query: 383 NKLSRFP 389
N+L+ P
Sbjct: 380 NQLTTLP 386
Score = 69.3 bits (162), Expect = 3e-11
Identities = 79/356 (22%), Positives = 148/356 (41%), Gaps = 12/356 (3%)
Query: 78 QPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELH 137
Q + ++ R+L + +N+ + F L+ L L L+ N+L+ + F GL +L L
Sbjct: 11 QVSIIISARDLSM--NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILM 68
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L +N + + +E L SL++L L N IS + R F L+ L L L DN LT++
Sbjct: 69 LQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVR 128
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ L+ + I + + L L L N ++L + F L L+ L
Sbjct: 129 ALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLD 188
Query: 258 LDGNQLS--VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L+ N+L + GR +E L N N I +F
Sbjct: 189 LNYNKLQEFPVAIRTLGRLQE---LGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI-QFV 244
Query: 316 LQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHL 375
++ + L T++ +G + + E L+ + + L ++ +P L
Sbjct: 245 GRSAFQYLPKLHTLSLNG-AMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+LS N++ P L + + L+ + + HN++ + +L ++ ++L N
Sbjct: 303 RVLELSHNQIEELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 299 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 398
Score = 48.4 bits (110), Expect = 7e-05
Identities = 49/207 (23%), Positives = 84/207 (40%), Gaps = 5/207 (2%)
Query: 82 FVNLRELHIVNSNVPSIGQF--SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
F L L ++ N + +F + L L+ L +NN+ ++ F G L +H
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I+ + F++L L TL L N + + L IL L+ + L +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMC 296
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ + LR+ + + + + H +LEE+ L N + +D F L L+ L L
Sbjct: 297 QQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS 354
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRNR 286
N + I F L L L+ N+
Sbjct: 355 WNAIRSIHPEAFSTLHSLVKLDLTDNQ 381
Score = 47.6 bits (108), Expect = 1e-04
Identities = 69/313 (22%), Positives = 116/313 (37%), Gaps = 9/313 (2%)
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK 240
+S DLS N LT+L P +F ++ L + L I Q + + L+ L L N
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 241 YLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXX 300
+ ++ L L+ L+LD N +S++ + F L L L N
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 301 XXXXDISHNKIDRFHLQTFA-PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANL 359
++ N+I H+ +A + SL ++ N + + + L + + L
Sbjct: 136 LQAMTLALNRIS--HIPDYAFQNLTSLVVLHLHNNRIQ-HLGTHSFEGLHNLETLDLNYN 192
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
LQE P T L L N + P K LQ + N +Q + Q
Sbjct: 193 KLQEFPVAIRTLG-RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQY 251
Query: 420 LEAIAEVNL--MKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
L + ++L + + L +T T + IR+L +L LS
Sbjct: 252 LPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLT--RAGIRLLPSGMCQQLPRLRVLELSH 309
Query: 478 EQLDPCPTTHEAQ 490
Q++ P+ H Q
Sbjct: 310 NQIEELPSLHRCQ 322
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 86.6 bits (205), Expect = 2e-16
Identities = 79/329 (24%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + I + W L +L+ L L N ++ V +F GL +L L LD N +
Sbjct: 115 SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +L +L+ + LA N+IS + F+ L L +L L +N + L F+ +
Sbjct: 175 TEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L+ I + RL+EL N K + F+ L+ + N +
Sbjct: 235 NLETLDLNYNKLQEFPVAI-RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F +LH L+L+ ++ I R +
Sbjct: 294 QFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPSGMCQQL 351
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ + S N + E L ++ +GL + + EI + F+ L ALDLSWN
Sbjct: 352 PRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
+ + S L +LD++ N+L TL
Sbjct: 409 AIRSIHPEAFSTLHSLVKLDLTDNQLTTL 437
Score = 82.2 bits (194), Expect = 4e-15
Identities = 81/322 (25%), Positives = 137/322 (42%), Gaps = 10/322 (3%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ L L L L N ++ + F+ + LR L I + + +P L+
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + + F L L L+ N+
Sbjct: 191 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK-LQEF 249
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
+N I + F L+TI+F N P+ + Q LP+
Sbjct: 250 PVAIRTLGRLQELGFHNNNIKAIPEKAFMG-NPLLQTIHFYDN--PIQFVGRSAFQYLPK 306
Query: 351 IHGVGL-ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+H + L + +QE P T + ++ L + +L P + + L+ L++SHN++
Sbjct: 307 LHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRL--LPSGMCQQLPRLRVLELSHNQI 364
Query: 410 QTLSEQDLQRLEAIAEVNLMKN 431
+ L L R + + E+ L N
Sbjct: 365 EEL--PSLHRCQKLEEIGLQHN 384
Score = 69.7 bits (163), Expect = 3e-11
Identities = 77/307 (25%), Positives = 129/307 (42%), Gaps = 8/307 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + + + SF GL +LR L L N LT + L L + L N I
Sbjct: 139 SLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRI 198
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++LTSL L L NN+I L + F L L LDL+ N L + P + +
Sbjct: 199 SHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLG 257
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ ++ I + + P L+ + +N +++ F L +L L L+G
Sbjct: 258 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD 317
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L +LTL+R ++SHN+I+
Sbjct: 318 IQEFPDLKGTT-SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL---PSLHRC 373
Query: 324 DSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L+ I N + EI A L + + L+ +++ I F+ LV LDL+
Sbjct: 374 QKLEEIGLQHNRIW--EIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTD 431
Query: 383 NKLSRFP 389
N+L+ P
Sbjct: 432 NQLTTLP 438
Score = 68.9 bits (161), Expect = 4e-11
Identities = 77/346 (22%), Positives = 142/346 (41%), Gaps = 10/346 (2%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + +N+ + F L+ L L L+ N+L+ + F GL +L L L +N + +
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E L SL++L L N IS + R F L+ L L L DN LT++ ++ L+
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 190
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS--V 265
+ I + + L L L N ++L + F L L+ L L+ N+L
Sbjct: 191 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP 250
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
+ GR +E L N N I +F ++ +
Sbjct: 251 VAIRTLGRLQE---LGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI-QFVGRSAFQYLPK 306
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L T++ +G + + E L+ + + L ++ +P L L+LS N++
Sbjct: 307 LHTLSLNG-AMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQI 364
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
P L + + L+ + + HN++ + +L ++ ++L N
Sbjct: 365 EELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 408
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 351 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 408
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 409 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 450
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/209 (26%), Positives = 81/209 (38%), Gaps = 5/209 (2%)
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
L P LDL N L F L+ L++L+L GN LS I F L +L L
Sbjct: 64 LDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQN 123
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI- 343
N+ + N I ++F + SL+ + N L EI +
Sbjct: 124 NQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEG-LSSLRHLWLDDN--ALTEIPVR 180
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
L LP + + LA + IP F LV L L N++ L+ LD
Sbjct: 181 ALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLD 240
Query: 404 ISHNKLQTLSEQDLQRLEAIAEVNLMKNN 432
+++NKLQ ++ L + E+ NN
Sbjct: 241 LNYNKLQEFPVA-IRTLGRLQELGFHNNN 268
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 86.6 bits (205), Expect = 2e-16
Identities = 79/329 (24%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + I + W L +L+ L L N ++ V +F GL +L L LD N +
Sbjct: 76 SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +L +L+ + LA N+IS + F+ L L +L L +N + L F+ +
Sbjct: 136 TEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLH 195
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L L+ I + RL+EL N K + F+ L+ + N +
Sbjct: 196 NLETLDLNYNKLQEFPVAI-RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI 254
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F +LH L+L+ ++ I R +
Sbjct: 255 QFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPSGMCQQL 312
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ + S N + E L ++ +GL + + EI + F+ L ALDLSWN
Sbjct: 313 PRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 369
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
+ + S L +LD++ N+L TL
Sbjct: 370 AIRSIHPEAFSTLHSLVKLDLTDNQLTTL 398
Score = 82.2 bits (194), Expect = 4e-15
Identities = 81/322 (25%), Positives = 137/322 (42%), Gaps = 10/322 (3%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ +
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ L L L L N ++ + F+ + LR L I + + +P L+
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 151
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + + F L L L+ N+
Sbjct: 152 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK-LQEF 210
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
+N I + F L+TI+F N P+ + Q LP+
Sbjct: 211 PVAIRTLGRLQELGFHNNNIKAIPEKAFMG-NPLLQTIHFYDN--PIQFVGRSAFQYLPK 267
Query: 351 IHGVGL-ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+H + L + +QE P T + ++ L + +L P + + L+ L++SHN++
Sbjct: 268 LHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRL--LPSGMCQQLPRLRVLELSHNQI 325
Query: 410 QTLSEQDLQRLEAIAEVNLMKN 431
+ L L R + + E+ L N
Sbjct: 326 EEL--PSLHRCQKLEEIGLQHN 345
Score = 69.7 bits (163), Expect = 3e-11
Identities = 77/307 (25%), Positives = 129/307 (42%), Gaps = 8/307 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + + + SF GL +LR L L N LT + L L + L N I
Sbjct: 100 SLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRI 159
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++LTSL L L NN+I L + F L L LDL+ N L + P + +
Sbjct: 160 SHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLG 218
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L+ ++ I + + P L+ + +N +++ F L +L L L+G
Sbjct: 219 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD 278
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L +LTL+R ++SHN+I+
Sbjct: 279 IQEFPDLKGTT-SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL---PSLHRC 334
Query: 324 DSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L+ I N + EI A L + + L+ +++ I F+ LV LDL+
Sbjct: 335 QKLEEIGLQHNRIW--EIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTD 392
Query: 383 NKLSRFP 389
N+L+ P
Sbjct: 393 NQLTTLP 399
Score = 68.9 bits (161), Expect = 4e-11
Identities = 77/346 (22%), Positives = 142/346 (41%), Gaps = 10/346 (2%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + +N+ + F L+ L L L+ N+L+ + F GL +L L L +N + +
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+E L SL++L L N IS + R F L+ L L L DN LT++ ++ L+
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 151
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS--V 265
+ I + + L L L N ++L + F L L+ L L+ N+L
Sbjct: 152 MTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFP 211
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
+ GR +E L N N I +F ++ +
Sbjct: 212 VAIRTLGRLQE---LGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPI-QFVGRSAFQYLPK 267
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L T++ +G + + E L+ + + L ++ +P L L+LS N++
Sbjct: 268 LHTLSLNG-AMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQI 325
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
P L + + L+ + + HN++ + +L ++ ++L N
Sbjct: 326 EELP--SLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 369
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 312 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 369
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 370 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 411
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/209 (26%), Positives = 81/209 (38%), Gaps = 5/209 (2%)
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
L P LDL N L F L+ L++L+L GN LS I F L +L L
Sbjct: 25 LDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQN 84
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI- 343
N+ + N I ++F + SL+ + N L EI +
Sbjct: 85 NQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEG-LSSLRHLWLDDN--ALTEIPVR 141
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
L LP + + LA + IP F LV L L N++ L+ LD
Sbjct: 142 ALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLD 201
Query: 404 ISHNKLQTLSEQDLQRLEAIAEVNLMKNN 432
+++NKLQ ++ L + E+ NN
Sbjct: 202 LNYNKLQEFPVA-IRTLGRLQELGFHNNN 229
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 86.6 bits (205), Expect = 2e-16
Identities = 77/275 (28%), Positives = 116/275 (42%), Gaps = 4/275 (1%)
Query: 159 TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
T L N I+ + + F L +L LDL N + L+P+ F+ + L LL+ +
Sbjct: 139 TYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQAL 198
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+ +L L N L+ F L+ L KL+LDGN L + D +F L
Sbjct: 199 APGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLL 258
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVDSLKTINFSGNNL 336
L L NR ++S N++ H TFAP + SL ++ S N+L
Sbjct: 259 YLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAP-LRSLSSLILSANSL 317
Query: 337 PLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
+ + Q LP + + L L + F E L L L N+LS+ P LL
Sbjct: 318 Q-HLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPL 376
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ LD+S N+L L L + E++L N
Sbjct: 377 HSLEALDLSGNELSALHPATFGHLGRLRELSLRNN 411
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 2/203 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L EL++ N+ + ++ + L+ LR+L N ++ + +F GL +L +L LD N +
Sbjct: 185 LEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALG 244
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
+ F L +L L L +N+I L F L KL L+LS N L + F +
Sbjct: 245 ALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPL 304
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+ L L+ + +I+ +PRL L L N +L + F L+ L++L+L+GN+
Sbjct: 305 RSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNR 364
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
LS + + L L LS N
Sbjct: 365 LSQLPTALLEPLHSLEALDLSGN 387
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/208 (31%), Positives = 94/208 (45%), Gaps = 2/208 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP LR L+ + + + + SF GL++L L L N L ++ F L NL LHL+
Sbjct: 204 APLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLE 263
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQI--STLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
N I + F L L+ L L+ N++ S + F L LS L LS N L L P
Sbjct: 264 SNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPR 323
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
+F+ + L + R L + + + + L EL L N L + L L+ L
Sbjct: 324 IFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALD 383
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L GN+LS + FG L L+L N
Sbjct: 384 LSGNELSALHPATFGHLGRLRELSLRNN 411
Score = 82.6 bits (195), Expect = 3e-15
Identities = 63/204 (30%), Positives = 99/204 (48%), Gaps = 2/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L +L + + + ++ F L NL L+L N + + + F L L L+L N +
Sbjct: 232 SLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANEL 291
Query: 144 EQM--SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
+ + TF L SL +LIL+ N + L R+F+ L +L +L L N LT L PE F
Sbjct: 292 QPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWG 351
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
++ LR + L ++ T + + LE LDL N L F L RL++L L N
Sbjct: 352 LEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNN 411
Query: 262 QLSVIVDNMFGRNRELHVLTLSRN 285
LS + ++F + L+ L L N
Sbjct: 412 ALSALSGDIFAASPALYRLDLDGN 435
Score = 78.2 bits (184), Expect = 7e-14
Identities = 88/349 (25%), Positives = 134/349 (38%), Gaps = 11/349 (3%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N I +++ F L L+ L L NQI +L + F L++L L L +N L L P
Sbjct: 142 LGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPG 201
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ LRI + R++ + + L +L L N L F L L L
Sbjct: 202 TLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLH 261
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDI--SHNKIDRFH 315
L+ N++ + N F + +L L LS N + S N +
Sbjct: 262 LESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLG 321
Query: 316 LQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNE 373
+ F + L ++ GN L E L+ L E+ L L ++P
Sbjct: 322 PRIFQHL-PRLGLLSLRGNQLTHLAPEAFWGLEALRELR---LEGNRLSQLPTALLEPLH 377
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
L ALDLS N+LS L+ L + +N L LS A+ ++L N W
Sbjct: 378 SLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGW 437
Query: 434 HCDQCSASNMLLYMTTTVLNSTIRV--LKCHSPLRLRGATFGSLSFEQL 480
CD C + +M + ++C P LRG L +QL
Sbjct: 438 TCD-CRLRGLKRWMGDWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQQL 485
Score = 75.8 bits (178), Expect = 4e-13
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 4/297 (1%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L N +T++ A +F L L L L +N I + +TF L+ L+ L L NN + L
Sbjct: 141 SLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAP 200
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L KL IL + N ++ L+ F+ ++ L + L + ++ + L L
Sbjct: 201 GTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYL 260
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDN--MFGRNRELHVLTLSRNRXXXX 290
L N ++L + F L +L+ L L N+L + + F R L L LS N
Sbjct: 261 HLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHL 320
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPE 350
+ N++ + F +++L+ + GN L A+ L+ L
Sbjct: 321 GPRIFQHLPRLGLLSLRGNQLTHLAPEAFWG-LEALRELRLEGNRLSQLPTAL-LEPLHS 378
Query: 351 IHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
+ + L+ L + F + L L L N LS + + + L RLD+ N
Sbjct: 379 LEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
Score = 73.3 bits (172), Expect = 2e-12
Identities = 72/291 (24%), Positives = 116/291 (39%), Gaps = 4/291 (1%)
Query: 95 VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL 154
+ +I F F L LR L+L +N + S+ F L L EL+L +N ++ ++ T L
Sbjct: 147 ITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPL 206
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
L+ L N+IS L F L L L L N L L VF + +L
Sbjct: 207 RKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 266
Query: 215 LRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
+R + + + +L L+L N + + F L+ L L L N L + +F
Sbjct: 267 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQ 326
Query: 273 RNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS 332
L +L+L N+ + N++ + P + SL+ ++ S
Sbjct: 327 HLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEP-LHSLEALDLS 385
Query: 333 GNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
GN L A L + + L N +L + + F + L LDL N
Sbjct: 386 GNELSALHPA-TFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/121 (32%), Positives = 54/121 (44%), Gaps = 2/121 (1%)
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
+GP Q P + L L + + + +FWGL+ LR L L N L+ + L
Sbjct: 320 LGPRIFQHLPRLGLLSLR--GNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLH 377
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+L L L N + + TF HL L+ L L NN +S L +F L LDL N
Sbjct: 378 SLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGW 437
Query: 192 T 192
T
Sbjct: 438 T 438
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 86.2 bits (204), Expect = 3e-16
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 1/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + + +F GL+ L L L+HN++ V A F L LT L+LDHN +
Sbjct: 76 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKV 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ L +L L L NN+I L + F+ L L LS+N L+ L P D++
Sbjct: 136 TELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVE 195
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR-LKKLKLDGNQ 262
+L F R L + + +EEL L N K + + F S R L+ L LD
Sbjct: 196 NLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN 255
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
L D F L + L NR
Sbjct: 256 LEKFSDGAFLGVTTLKHVHLENNR 279
Score = 83.4 bits (197), Expect = 2e-15
Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 4/248 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N P + SF + NL L+L H + V A FRGL L L+L HN I +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVR 115
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ F LT L L L +N+++ L L L L IL L++N + +L F+ + LR
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRW 175
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
L + V L + + N S L+ +++LKL N L I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 268 DNMF-GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSL 326
DN F R L L L + +N++++ L + P DSL
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ--LPSNFP-FDSL 292
Query: 327 KTINFSGN 334
+T+ + N
Sbjct: 293 ETLALTNN 300
Score = 79.0 bits (186), Expect = 4e-14
Identities = 52/179 (29%), Positives = 83/179 (46%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ ++LNL NN + A++FR + NL LHL H I ++++ FR L L L L++N
Sbjct: 51 EKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHND 110
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I + + F L +L+ L L N +T+L + + +L I + +R + +
Sbjct: 111 IRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGA 170
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L L L EN L ++ L K +D NQLS + R + L LS N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHN 229
Score = 52.4 bits (120), Expect = 4e-06
Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 8/211 (3%)
Query: 226 VPRLEE----LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
+P++ E L+L N F L ++ F ++ L L L Q+ + F ++L L
Sbjct: 46 IPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLY 105
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS N + HNK+ +P+V+ L + NN + E+
Sbjct: 106 LSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN-LFILQL--NNNKIREL 162
Query: 342 -AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A Q ++ + L+ +L + E+L + N+LS +P LSK + ++
Sbjct: 163 RAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L +SHN L+++ + Q E + N
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 85.8 bits (203), Expect = 4e-16
Identities = 83/363 (22%), Positives = 155/363 (42%), Gaps = 11/363 (3%)
Query: 72 IGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
I + P P + L EL + + + I + +F GL +L+VL L +N L V + + L
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L L LD NHI + F L SL+ L L +N ++ + + FR L+ L + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFIS 249
+ + F ++ L + + + + + + LE LDL NL ++ T+ +
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIR--T 255
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISH- 308
L LK+L N + I + F N L + N ++
Sbjct: 256 LSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGA 315
Query: 309 NKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNF 368
++I F T ++SL ++LP V LP + + L+ L+++P
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQT----VCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 369 FTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
F+ + L +DL N++ + L+ L+++ NK+ + L ++ +++L
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDL 429
Query: 429 MKN 431
N
Sbjct: 430 SSN 432
Score = 84.6 bits (200), Expect = 8e-16
Identities = 88/340 (25%), Positives = 147/340 (43%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + +++ + F GL +LR L L N LT + FR L L + L N I
Sbjct: 139 SLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI 198
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F +L+SL L L NN+I +L + F L L LDL+ N L + P + +
Sbjct: 199 HHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLS 257
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ +R I + + P L + +N +++ F L L+ L L+G
Sbjct: 258 NLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 317
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 318 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 373
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 374 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 433 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 471
Score = 77.4 bits (182), Expect = 1e-13
Identities = 75/328 (22%), Positives = 138/328 (42%), Gaps = 6/328 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ L +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL N + + F+ L + N +
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPI 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F EL LTL+ ++ +I QT +
Sbjct: 294 QFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTGAQISSLP-QTVCNQL 351
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+L+ ++ S N L E + ++ + L + + EI + F L +L+L+WN
Sbjct: 352 PNLQVLDLSYN---LLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQT 411
K++ S L +LD+S N L +
Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSS 436
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/315 (26%), Positives = 133/315 (42%), Gaps = 9/315 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
S+N I + F SL TI+F N P+ + Q LPE
Sbjct: 251 TAIRTLSNLKELGFHSNN-IRSIPEKAFVG-NPSLITIHFYDN--PIQFVGRSAFQHLPE 306
Query: 351 IHGVGLANLS-LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L S + E P T +L +L L+ ++S P + ++ LQ LD+S+N L
Sbjct: 307 LRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLL 364
Query: 410 QTL-SEQDLQRLEAI 423
+ L S Q+L+ I
Sbjct: 365 EDLPSFSVCQKLQKI 379
Score = 34.7 bits (76), Expect = 0.88
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N L + SL+ L++L+L GN L+ I F L VL L N+
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ ++D H+ P FSG L +
Sbjct: 131 TEALQNLRS-----LQSLRLDANHISYVPPSC-------FSG--------------LHSL 164
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ L + +L EIP F L A+ L+ NK+ P L L + +N++ +
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
L ++ L ++ ++L NN
Sbjct: 225 LGKKCFDGLHSLETLDLNYNN 245
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 85.8 bits (203), Expect = 4e-16
Identities = 83/363 (22%), Positives = 155/363 (42%), Gaps = 11/363 (3%)
Query: 72 IGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
I + P P + L EL + + + I + +F GL +L+VL L +N L V + + L
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L L LD NHI + F L SL+ L L +N ++ + + FR L+ L + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFIS 249
+ + F ++ L + + + + + + LE LDL NL ++ T+ +
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIR--T 255
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISH- 308
L LK+L N + I + F N L + N ++
Sbjct: 256 LSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGA 315
Query: 309 NKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNF 368
++I F T ++SL ++LP V LP + + L+ L+++P
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQT----VCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 369 FTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
F+ + L +DL N++ + L+ L+++ NK+ + L ++ +++L
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDL 429
Query: 429 MKN 431
N
Sbjct: 430 SSN 432
Score = 84.6 bits (200), Expect = 8e-16
Identities = 88/340 (25%), Positives = 147/340 (43%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + +++ + F GL +LR L L N LT + FR L L + L N I
Sbjct: 139 SLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI 198
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F +L+SL L L NN+I +L + F L L LDL+ N L + P + +
Sbjct: 199 HHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLS 257
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ +R I + + P L + +N +++ F L L+ L L+G
Sbjct: 258 NLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 317
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 318 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 373
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 374 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 433 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 471
Score = 77.4 bits (182), Expect = 1e-13
Identities = 75/328 (22%), Positives = 138/328 (42%), Gaps = 6/328 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ L +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL N + + F+ L + N +
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPI 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F EL LTL+ ++ +I QT +
Sbjct: 294 QFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTGAQISSLP-QTVCNQL 351
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+L+ ++ S N L E + ++ + L + + EI + F L +L+L+WN
Sbjct: 352 PNLQVLDLSYN---LLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQT 411
K++ S L +LD+S N L +
Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSS 436
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/315 (26%), Positives = 133/315 (42%), Gaps = 9/315 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
S+N I + F SL TI+F N P+ + Q LPE
Sbjct: 251 TAIRTLSNLKELGFHSNN-IRSIPEKAFVG-NPSLITIHFYDN--PIQFVGRSAFQHLPE 306
Query: 351 IHGVGLANLS-LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L S + E P T +L +L L+ ++S P + ++ LQ LD+S+N L
Sbjct: 307 LRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLL 364
Query: 410 QTL-SEQDLQRLEAI 423
+ L S Q+L+ I
Sbjct: 365 EDLPSFSVCQKLQKI 379
Score = 34.7 bits (76), Expect = 0.88
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N L + SL+ L++L+L GN L+ I F L VL L N+
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ ++D H+ P FSG L +
Sbjct: 131 TEALQNLRS-----LQSLRLDANHISYVPPSC-------FSG--------------LHSL 164
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ L + +L EIP F L A+ L+ NK+ P L L + +N++ +
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
L ++ L ++ ++L NN
Sbjct: 225 LGKKCFDGLHSLETLDLNYNN 245
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 64/204 (31%), Positives = 94/204 (46%), Gaps = 1/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + + +F GL+ L L L+HN++ + A F L LT L+LDHN +
Sbjct: 76 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ L +L L L NN+I L + F+ L L LS+N L+ L P D++
Sbjct: 136 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 195
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR-LKKLKLDGNQ 262
+L F R L + + +EEL L N K + + F S R L+ L LD
Sbjct: 196 NLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN 255
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
L D F L + L NR
Sbjct: 256 LEKFSDGAFLGVTTLKHVHLENNR 279
Score = 84.6 bits (200), Expect = 8e-16
Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 4/248 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N P + SF + NL L+L H + V A FRGL L L+L HN I +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ F LT L L L +N+++ L L L L IL L++N + +L F+ + LR
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
L + V L + + N S L+ +++LKL N L I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 268 DNMF-GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSL 326
DN F R L L L + +N++++ L + P DSL
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ--LPSNFP-FDSL 292
Query: 327 KTINFSGN 334
+T+ + N
Sbjct: 293 ETLALTNN 300
Score = 81.0 bits (191), Expect = 1e-14
Identities = 53/179 (29%), Positives = 83/179 (46%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ ++LNL NN + A++FR + NL LHL H I ++++ FR L L L L++N
Sbjct: 51 EKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHND 110
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I L + F L +L+ L L N +T+L + + +L I + +R + +
Sbjct: 111 IRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGA 170
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L L L EN L ++ L K +D NQLS + R + L LS N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHN 229
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 8/211 (3%)
Query: 226 VPRLEE----LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
+P++ E L+L N F L ++ F ++ L L L Q+ + F ++L L
Sbjct: 46 IPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLY 105
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS N + HNK+ +P+V+ L + NN + E+
Sbjct: 106 LSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN-LFILQL--NNNKIREL 162
Query: 342 -AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A Q ++ + L+ +L + E+L + N+LS +P LSK + ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L +SHN L+++ + Q E + N
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 64/204 (31%), Positives = 94/204 (46%), Gaps = 1/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + + +F GL+ L L L+HN++ + A F L LT L+LDHN +
Sbjct: 76 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ L +L L L NN+I L + F+ L L LS+N L+ L P D++
Sbjct: 136 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 195
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR-LKKLKLDGNQ 262
+L F R L + + +EEL L N K + + F S R L+ L LD
Sbjct: 196 NLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN 255
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
L D F L + L NR
Sbjct: 256 LEKFSDGAFLGVTTLKHVHLENNR 279
Score = 84.6 bits (200), Expect = 8e-16
Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 4/248 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N P + SF + NL L+L H + V A FRGL L L+L HN I +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ F LT L L L +N+++ L L L L IL L++N + +L F+ + LR
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
L + V L + + N S L+ +++LKL N L I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 268 DNMF-GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSL 326
DN F R L L L + +N++++ L + P DSL
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ--LPSNFP-FDSL 292
Query: 327 KTINFSGN 334
+T+ + N
Sbjct: 293 ETLALTNN 300
Score = 81.0 bits (191), Expect = 1e-14
Identities = 53/179 (29%), Positives = 83/179 (46%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ ++LNL NN + A++FR + NL LHL H I ++++ FR L L L L++N
Sbjct: 51 EKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHND 110
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I L + F L +L+ L L N +T+L + + +L I + +R + +
Sbjct: 111 IRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGA 170
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L L L EN L ++ L K +D NQLS + R + L LS N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHN 229
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 8/211 (3%)
Query: 226 VPRLEE----LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
+P++ E L+L N F L ++ F ++ L L L Q+ + F ++L L
Sbjct: 46 IPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLY 105
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS N + HNK+ +P+V+ L + NN + E+
Sbjct: 106 LSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN-LFILQL--NNNKIREL 162
Query: 342 -AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A Q ++ + L+ +L + E+L + N+LS +P LSK + ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L +SHN L+++ + Q E + N
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 64/204 (31%), Positives = 94/204 (46%), Gaps = 1/204 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL LH+ + + + +F GL+ L L L+HN++ + A F L LT L+LDHN +
Sbjct: 76 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ L +L L L NN+I L + F+ L L LS+N L+ L P D++
Sbjct: 136 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 195
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR-LKKLKLDGNQ 262
+L F R L + + +EEL L N K + + F S R L+ L LD
Sbjct: 196 NLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN 255
Query: 263 LSVIVDNMFGRNRELHVLTLSRNR 286
L D F L + L NR
Sbjct: 256 LEKFSDGAFLGVTTLKHVHLENNR 279
Score = 84.6 bits (200), Expect = 8e-16
Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 4/248 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ +N P + SF + NL L+L H + V A FRGL L L+L HN I +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
+ F LT L L L +N+++ L L L L IL L++N + +L F+ + LR
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
L + V L + + N S L+ +++LKL N L I
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIP 235
Query: 268 DNMF-GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSL 326
DN F R L L L + +N++++ L + P DSL
Sbjct: 236 DNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ--LPSNFP-FDSL 292
Query: 327 KTINFSGN 334
+T+ + N
Sbjct: 293 ETLALTNN 300
Score = 81.0 bits (191), Expect = 1e-14
Identities = 53/179 (29%), Positives = 83/179 (46%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ ++LNL NN + A++FR + NL LHL H I ++++ FR L L L L++N
Sbjct: 51 EKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHND 110
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I L + F L +L+ L L N +T+L + + +L I + +R + +
Sbjct: 111 IRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGA 170
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L L L EN L ++ L K +D NQLS + R + L LS N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHN 229
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 8/211 (3%)
Query: 226 VPRLEE----LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
+P++ E L+L N F L ++ F ++ L L L Q+ + F ++L L
Sbjct: 46 IPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLY 105
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS N + HNK+ +P+V+ L + NN + E+
Sbjct: 106 LSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN-LFILQL--NNNKIREL 162
Query: 342 -AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A Q ++ + L+ +L + E+L + N+LS +P LSK + ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L +SHN L+++ + Q E + N
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 85.8 bits (203), Expect = 4e-16
Identities = 83/363 (22%), Positives = 155/363 (42%), Gaps = 11/363 (3%)
Query: 72 IGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
I + P P + L EL + + + I + +F GL +L+VL L +N L V + + L
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L L LD NHI + F L SL+ L L +N ++ + + FR L+ L + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFIS 249
+ + F ++ L + + + + + + LE LDL NL ++ T+ +
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIR--T 255
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISH- 308
L LK+L N + I + F N L + N ++
Sbjct: 256 LSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGA 315
Query: 309 NKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNF 368
++I F T ++SL ++LP V LP + + L+ L+++P
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQT----VCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 369 FTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
F+ + L +DL N++ + L+ L+++ NK+ + L ++ +++L
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDL 429
Query: 429 MKN 431
N
Sbjct: 430 SSN 432
Score = 84.6 bits (200), Expect = 8e-16
Identities = 88/340 (25%), Positives = 147/340 (43%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + +++ + F GL +LR L L N LT + FR L L + L N I
Sbjct: 139 SLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI 198
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F +L+SL L L NN+I +L + F L L LDL+ N L + P + +
Sbjct: 199 HHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLS 257
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ +R I + + P L + +N +++ F L L+ L L+G
Sbjct: 258 NLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 317
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 318 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 373
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 374 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 433 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 471
Score = 77.4 bits (182), Expect = 1e-13
Identities = 75/328 (22%), Positives = 138/328 (42%), Gaps = 6/328 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ L +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL N + + F+ L + N +
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPI 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F EL LTL+ ++ +I QT +
Sbjct: 294 QFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTGAQISSLP-QTVCNQL 351
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+L+ ++ S N L E + ++ + L + + EI + F L +L+L+WN
Sbjct: 352 PNLQVLDLSYN---LLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQT 411
K++ S L +LD+S N L +
Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSS 436
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/315 (26%), Positives = 133/315 (42%), Gaps = 9/315 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
S+N I + F SL TI+F N P+ + Q LPE
Sbjct: 251 TAIRTLSNLKELGFHSNN-IRSIPEKAFVG-NPSLITIHFYDN--PIQFVGRSAFQHLPE 306
Query: 351 IHGVGLANLS-LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L S + E P T +L +L L+ ++S P + ++ LQ LD+S+N L
Sbjct: 307 LRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLL 364
Query: 410 QTL-SEQDLQRLEAI 423
+ L S Q+L+ I
Sbjct: 365 EDLPSFSVCQKLQKI 379
Score = 34.7 bits (76), Expect = 0.88
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 26/201 (12%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
LDL N L + SL+ L++L+L GN L+ I F L VL L N+
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
+ ++D H+ P FSG L +
Sbjct: 131 TEALQNLRS-----LQSLRLDANHISYVPPSC-------FSG--------------LHSL 164
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
+ L + +L EIP F L A+ L+ NK+ P L L + +N++ +
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
L ++ L ++ ++L NN
Sbjct: 225 LGKKCFDGLHSLETLDLNYNN 245
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/204 (30%), Positives = 99/204 (48%), Gaps = 3/204 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VN R L++ + + I +F L++L +L L+ N + + F GL +L L L N
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKD 201
+ + ++ F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+ +LR C L+ I + LV RLEEL+L N + F L L+KL L
Sbjct: 206 LVNLRYLNLGMCNLKDI-PNLTALV-RLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 262 QLSVIVDNMFGRNRELHVLTLSRN 285
Q++ I N F + L L LS N
Sbjct: 264 QVATIERNAFDDLKSLEELNLSHN 287
Score = 73.3 bits (172), Expect = 2e-12
Identities = 58/216 (26%), Positives = 94/216 (43%), Gaps = 3/216 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N R LNL N + + D F+ L +L L L N + ++ F L SL TL L +N++
Sbjct: 87 NTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRL 146
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC-LLRRINTQIYHLV 226
+T+ ++ F L+KL L L +NP+ + F + LR L I+ + +
Sbjct: 147 TTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGL 206
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L+LG K + + +L RL++L+L GN+L +I F L L L +
Sbjct: 207 VNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQ 264
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
++SHN + F P+
Sbjct: 265 VATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPL 300
Score = 72.5 bits (170), Expect = 4e-12
Identities = 60/207 (28%), Positives = 92/207 (44%), Gaps = 4/207 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N L+L N I+ + ++TF+HL L+ L L+ N + + F L L+ L+L DN
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE-NLFKYLTSDEFIS 249
LT + + F+ + LR R + I + ++ VP L LDLGE +Y++ F
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHN 309
L L+ L L L I N+ R L L LS NR + H
Sbjct: 206 LVNLRYLNLGMCNLKDI-PNLTALVR-LEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 310 KIDRFHLQTFAPVVDSLKTINFSGNNL 336
++ F + SL+ +N S NNL
Sbjct: 264 QVATIERNAFDD-LKSLEELNLSHNNL 289
Score = 63.7 bits (148), Expect = 2e-09
Identities = 62/258 (24%), Positives = 101/258 (39%), Gaps = 4/258 (1%)
Query: 218 INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
I T + + LE L L +NL + + F L L L+L N+L+ + F +L
Sbjct: 101 IRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKL 160
Query: 278 HVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP 337
L L N D+ K + + + +L+ +N NL
Sbjct: 161 RELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNL- 219
Query: 338 LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTK 397
+I L L + + L+ L I F L L L +++ K
Sbjct: 220 -KDIPN-LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK 277
Query: 398 FLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIR 457
L+ L++SHN L +L L + V+L N WHC+ C + ++ TV ++T
Sbjct: 278 SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLSWWLKETVPSNTTC 336
Query: 458 VLKCHSPLRLRGATFGSL 475
+CH+P L+G G L
Sbjct: 337 CARCHAPAGLKGRYIGEL 354
Score = 48.0 bits (109), Expect = 9e-05
Identities = 24/58 (41%), Positives = 39/58 (67%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LR+L ++++ V +I + +F L++L LNL+HNNL S+ D F L L +HL+HN
Sbjct: 254 SLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Score = 46.8 bits (106), Expect = 2e-04
Identities = 45/172 (26%), Positives = 81/172 (47%), Gaps = 6/172 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN 126
N LT P TQ +++ LREL + N+ + SI ++F + +LR L+L +++
Sbjct: 144 NRLTTVP--TQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEA 201
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
F GL+NL L+L +++ + + T L L+ L L+ N++ + F+ L L L
Sbjct: 202 AFEGLVNLRYLNLGMCNLKDIPNLTA--LVRLEELELSGNRLDLIRPGSFQGLTSLRKLW 259
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + F D++ L L + ++ + RLE + L N
Sbjct: 260 LMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 29/207 (14%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L + + V + +FWGL N+ +L L HNNLT + GL+ L ELHL N I
Sbjct: 241 LKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN 300
Query: 145 QMSSE-------------TFRHLTS-----------LKTLILANNQISTLVSRLFRMLAK 180
++S + TF HL+ L TL + NN++S + FR L+
Sbjct: 301 RISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSS 360
Query: 181 LSILDLSDNPLT----DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
L LDL +N ++ D+N F + LR + +R I + + + LE LDL +
Sbjct: 361 LKTLDLKNNEISWTIEDMN-GAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 237 NLFKYLTSDEFISLKRLKKLKLDGNQL 263
N L + F +K+L++L L+ + L
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 78.6 bits (185), Expect = 5e-14
Identities = 89/402 (22%), Positives = 175/402 (43%), Gaps = 22/402 (5%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
+LRE+ + N+ +P++G S N+ +L+L N + ++ ++ + +L L L
Sbjct: 99 SLREVKLNNNELETIPNLGPVS----ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 154
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F L LK L L +N+++++ F LA L +L L+ N ++ + P++F
Sbjct: 155 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 212
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
K +QHL + R ++ ++ + + L+ L + N L F L ++ L+
Sbjct: 213 KLPQLQHLEL---NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 269
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
LD N L+ I L L LS+N D++ N + R
Sbjct: 270 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDS 329
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEH 374
+F + L T++ GNN + L + + L N + E F+ +
Sbjct: 330 SFLGL-SLLNTLHI-GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDK 387
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N++ K + L+ LD+S N + +L +++ + +++L ++
Sbjct: 388 LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLS 476
CD C + ++ S + C P L+G + ++S
Sbjct: 448 CD-CQLKWLPQWVAENNFQSFVNA-SCAHPQLLKGRSIFAVS 487
Score = 73.7 bits (173), Expect = 2e-12
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 12/303 (3%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ L L HN + + + + HL SL+ + L NN++ T + L + A +++L L+ N +
Sbjct: 76 VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRIV 134
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL-K 251
++ PE K+ Q L + + T L +L+ L L N + F +L
Sbjct: 135 EILPEHLKEFQSLETLDLSSNNISELQTAFPAL--QLKYLYLNSNRVTSMEPGYFDNLAN 192
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
L LKL+ N++S I MF + +L L L+RN+ + N +
Sbjct: 193 TLLVLKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGV 251
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFF 369
+ F + +++ + NNL L +L E+H L+ ++ I + +
Sbjct: 252 TKLMDGAFWG-LSNMEILQLDHNNLTEITKGWLYGLLMLQELH---LSQNAINRISPDAW 307
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ + L LDL++N LSR L L I +N++ +++ + L ++ ++L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDL- 366
Query: 430 KNN 432
KNN
Sbjct: 367 KNN 369
Score = 67.7 bits (158), Expect = 1e-10
Identities = 61/231 (26%), Positives = 102/231 (44%), Gaps = 4/231 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN-LTELHLDH 140
F +L L + ++N+ + Q +F LQ L+ L L N +TS+ F L N L L L+
Sbjct: 144 FQSLETLDLSSNNISEL-QTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNR 201
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I + + F+ L L+ L L N+I + F+ L L L + N +T L F
Sbjct: 202 NRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFW 260
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+ ++ I + L I + + L+EL L +N ++ D + ++L +L L
Sbjct: 261 GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTF 320
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
N LS + D+ F L+ L + NR D+ +N+I
Sbjct: 321 NHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEI 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LD S +L+R P L S ++ RLD+SHN+L + + L+++ EV L N
Sbjct: 58 LDCSRKRLARLPEPLPS---WVARLDLSHNRLSFIKASSMSHLQSLREVKLNNN 108
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 29/207 (14%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L + + V + +FWGL N+ +L L HNNLT + GL+ L ELHL N I
Sbjct: 241 LKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN 300
Query: 145 QMSSE-------------TFRHLTS-----------LKTLILANNQISTLVSRLFRMLAK 180
++S + TF HL+ L TL + NN++S + FR L+
Sbjct: 301 RISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSS 360
Query: 181 LSILDLSDNPLT----DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
L LDL +N ++ D+N F + LR + +R I + + + LE LDL +
Sbjct: 361 LKTLDLKNNEISWTIEDMN-GAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 237 NLFKYLTSDEFISLKRLKKLKLDGNQL 263
N L + F +K+L++L L+ + L
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 78.6 bits (185), Expect = 5e-14
Identities = 89/402 (22%), Positives = 175/402 (43%), Gaps = 22/402 (5%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
+LRE+ + N+ +P++G S N+ +L+L N + ++ ++ + +L L L
Sbjct: 99 SLREVKLNNNELETIPNLGPVS----ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 154
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F L LK L L +N+++++ F LA L +L L+ N ++ + P++F
Sbjct: 155 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 212
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
K +QHL + R ++ ++ + + L+ L + N L F L ++ L+
Sbjct: 213 KLPQLQHLEL---NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 269
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
LD N L+ I L L LS+N D++ N + R
Sbjct: 270 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDS 329
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEH 374
+F + L T++ GNN + L + + L N + E F+ +
Sbjct: 330 SFLGL-SLLNTLHI-GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDK 387
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N++ K + L+ LD+S N + +L +++ + +++L ++
Sbjct: 388 LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLS 476
CD C + ++ S + C P L+G + ++S
Sbjct: 448 CD-CQLKWLPQWVAENNFQSFVNA-SCAHPQLLKGRSIFAVS 487
Score = 73.7 bits (173), Expect = 2e-12
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 12/303 (3%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ L L HN + + + + HL SL+ + L NN++ T + L + A +++L L+ N +
Sbjct: 76 VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRIV 134
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL-K 251
++ PE K+ Q L + + T L +L+ L L N + F +L
Sbjct: 135 EILPEHLKEFQSLETLDLSSNNISELQTAFPAL--QLKYLYLNSNRVTSMEPGYFDNLAN 192
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
L LKL+ N++S I MF + +L L L+RN+ + N +
Sbjct: 193 TLLVLKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGV 251
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFF 369
+ F + +++ + NNL L +L E+H L+ ++ I + +
Sbjct: 252 TKLMDGAFWG-LSNMEILQLDHNNLTEITKGWLYGLLMLQELH---LSQNAINRISPDAW 307
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ + L LDL++N LSR L L I +N++ +++ + L ++ ++L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDL- 366
Query: 430 KNN 432
KNN
Sbjct: 367 KNN 369
Score = 67.7 bits (158), Expect = 1e-10
Identities = 61/231 (26%), Positives = 102/231 (44%), Gaps = 4/231 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN-LTELHLDH 140
F +L L + ++N+ + Q +F LQ L+ L L N +TS+ F L N L L L+
Sbjct: 144 FQSLETLDLSSNNISEL-QTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNR 201
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I + + F+ L L+ L L N+I + F+ L L L + N +T L F
Sbjct: 202 NRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFW 260
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+ ++ I + L I + + L+EL L +N ++ D + ++L +L L
Sbjct: 261 GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTF 320
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
N LS + D+ F L+ L + NR D+ +N+I
Sbjct: 321 NHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEI 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LD S +L+R P L S ++ RLD+SHN+L + + L+++ EV L N
Sbjct: 58 LDCSRKRLARLPEPLPS---WVARLDLSHNRLSFIKASSMSHLQSLREVKLNNN 108
>BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for
IMAGE:5200456) protein.
Length = 634
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/204 (30%), Positives = 99/204 (48%), Gaps = 3/204 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VN R L++ + + I +F L++L +L L+ N + + F GL +L L L N
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKD 201
+ + ++ F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+ +LR C L+ I + LV RLEEL+L N + F L L+KL L
Sbjct: 206 LVNLRYLNLGMCNLKDI-PNLTALV-RLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 262 QLSVIVDNMFGRNRELHVLTLSRN 285
Q++ I N F + L L LS N
Sbjct: 264 QVATIERNAFDDLKSLEELNLSHN 287
Score = 73.3 bits (172), Expect = 2e-12
Identities = 58/216 (26%), Positives = 94/216 (43%), Gaps = 3/216 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N R LNL N + + D F+ L +L L L N + ++ F L SL TL L +N++
Sbjct: 87 NTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRL 146
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC-LLRRINTQIYHLV 226
+T+ ++ F L+KL L L +NP+ + F + LR L I+ + +
Sbjct: 147 TTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGL 206
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L+LG K + + +L RL++L+L GN+L +I F L L L +
Sbjct: 207 VNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQ 264
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
++SHN + F P+
Sbjct: 265 VATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPL 300
Score = 72.5 bits (170), Expect = 4e-12
Identities = 60/207 (28%), Positives = 92/207 (44%), Gaps = 4/207 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N L+L N I+ + ++TF+HL L+ L L+ N + + F L L+ L+L DN
Sbjct: 86 VNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNR 145
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE-NLFKYLTSDEFIS 249
LT + + F+ + LR R + I + ++ VP L LDLGE +Y++ F
Sbjct: 146 LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEG 205
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHN 309
L L+ L L L I N+ R L L LS NR + H
Sbjct: 206 LVNLRYLNLGMCNLKDI-PNLTALVR-LEELELSGNRLDLIRPGSFQGLTSLRKLWLMHA 263
Query: 310 KIDRFHLQTFAPVVDSLKTINFSGNNL 336
++ F + SL+ +N S NNL
Sbjct: 264 QVATIERNAFDD-LKSLEELNLSHNNL 289
Score = 63.7 bits (148), Expect = 2e-09
Identities = 62/258 (24%), Positives = 101/258 (39%), Gaps = 4/258 (1%)
Query: 218 INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
I T + + LE L L +NL + + F L L L+L N+L+ + F +L
Sbjct: 101 IRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKL 160
Query: 278 HVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP 337
L L N D+ K + + + +L+ +N NL
Sbjct: 161 RELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNL- 219
Query: 338 LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTK 397
+I L L + + L+ L I F L L L +++ K
Sbjct: 220 -KDIPN-LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK 277
Query: 398 FLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIR 457
L+ L++SHN L +L L + V+L N WHC+ C + ++ TV ++T
Sbjct: 278 SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLSWWLKETVPSNTTC 336
Query: 458 VLKCHSPLRLRGATFGSL 475
+CH+P L+G G L
Sbjct: 337 CARCHAPAGLKGRYIGEL 354
Score = 48.0 bits (109), Expect = 9e-05
Identities = 24/58 (41%), Positives = 39/58 (67%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LR+L ++++ V +I + +F L++L LNL+HNNL S+ D F L L +HL+HN
Sbjct: 254 SLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Score = 46.8 bits (106), Expect = 2e-04
Identities = 45/172 (26%), Positives = 81/172 (47%), Gaps = 6/172 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN 126
N LT P TQ +++ LREL + N+ + SI ++F + +LR L+L +++
Sbjct: 144 NRLTTVP--TQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEA 201
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
F GL+NL L+L +++ + + T L L+ L L+ N++ + F+ L L L
Sbjct: 202 AFEGLVNLRYLNLGMCNLKDIPNLTA--LVRLEELELSGNRLDLIRPGSFQGLTSLRKLW 259
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + F D++ L L + ++ + RLE + L N
Sbjct: 260 LMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 29/207 (14%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L + + V + +FWGL N+ +L L HNNLT + GL+ L ELHL N I
Sbjct: 241 LKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN 300
Query: 145 QMSSE-------------TFRHLTS-----------LKTLILANNQISTLVSRLFRMLAK 180
++S + TF HL+ L TL + NN++S + FR L+
Sbjct: 301 RISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSS 360
Query: 181 LSILDLSDNPLT----DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
L LDL +N ++ D+N F + LR + +R I + + + LE LDL +
Sbjct: 361 LKTLDLKNNEISWTIEDMN-GAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 237 NLFKYLTSDEFISLKRLKKLKLDGNQL 263
N L + F +K+L++L L+ + L
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 78.6 bits (185), Expect = 5e-14
Identities = 89/402 (22%), Positives = 175/402 (43%), Gaps = 22/402 (5%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
+LRE+ + N+ +P++G S N+ +L+L N + ++ ++ + +L L L
Sbjct: 99 SLREVKLNNNELETIPNLGPVS----ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 154
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F L LK L L +N+++++ F LA L +L L+ N ++ + P++F
Sbjct: 155 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 212
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
K +QHL + R ++ ++ + + L+ L + N L F L ++ L+
Sbjct: 213 KLPQLQHLEL---NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 269
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
LD N L+ I L L LS+N D++ N + R
Sbjct: 270 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDS 329
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEH 374
+F + L T++ GNN + L + + L N + E F+ +
Sbjct: 330 SFLGL-SLLNTLHI-GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDK 387
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N++ K + L+ LD+S N + +L +++ + +++L ++
Sbjct: 388 LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLS 476
CD C + ++ S + C P L+G + ++S
Sbjct: 448 CD-CQLKWLPQWVAENNFQSFVNA-SCAHPQLLKGRSIFAVS 487
Score = 73.7 bits (173), Expect = 2e-12
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 12/303 (3%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ L L HN + + + + HL SL+ + L NN++ T + L + A +++L L+ N +
Sbjct: 76 VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRIV 134
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL-K 251
++ PE K+ Q L + + T L +L+ L L N + F +L
Sbjct: 135 EILPEHLKEFQSLETLDLSSNNISELQTAFPAL--QLKYLYLNSNRVTSMEPGYFDNLAN 192
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
L LKL+ N++S I MF + +L L L+RN+ + N +
Sbjct: 193 TLLVLKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGV 251
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFF 369
+ F + +++ + NNL L +L E+H L+ ++ I + +
Sbjct: 252 TKLMDGAFWG-LSNMEILQLDHNNLTEITKGWLYGLLMLQELH---LSQNAINRISPDAW 307
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ + L LDL++N LSR L L I +N++ +++ + L ++ ++L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDL- 366
Query: 430 KNN 432
KNN
Sbjct: 367 KNN 369
Score = 67.7 bits (158), Expect = 1e-10
Identities = 61/231 (26%), Positives = 102/231 (44%), Gaps = 4/231 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN-LTELHLDH 140
F +L L + ++N+ + Q +F LQ L+ L L N +TS+ F L N L L L+
Sbjct: 144 FQSLETLDLSSNNISEL-QTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNR 201
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I + + F+ L L+ L L N+I + F+ L L L + N +T L F
Sbjct: 202 NRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFW 260
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+ ++ I + L I + + L+EL L +N ++ D + ++L +L L
Sbjct: 261 GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTF 320
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
N LS + D+ F L+ L + NR D+ +N+I
Sbjct: 321 NHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEI 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LD S +L+R P L S ++ RLD+SHN+L + + L+++ EV L N
Sbjct: 58 LDCSRKRLARLPEPLPS---WVARLDLSHNRLSFIKASSMSHLQSLREVKLNNN 108
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 29/207 (14%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L + + V + +FWGL N+ +L L HNNLT + GL+ L ELHL N I
Sbjct: 181 LKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN 240
Query: 145 QMSSE-------------TFRHLTS-----------LKTLILANNQISTLVSRLFRMLAK 180
++S + TF HL+ L TL + NN++S + FR L+
Sbjct: 241 RISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSS 300
Query: 181 LSILDLSDNPLT----DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
L LDL +N ++ D+N F + LR + +R I + + + LE LDL +
Sbjct: 301 LKTLDLKNNEISWTIEDMN-GAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 359
Query: 237 NLFKYLTSDEFISLKRLKKLKLDGNQL 263
N L + F +K+L++L L+ + L
Sbjct: 360 NAIMSLQGNAFSQMKKLQQLHLNTSSL 386
Score = 78.6 bits (185), Expect = 5e-14
Identities = 89/402 (22%), Positives = 175/402 (43%), Gaps = 22/402 (5%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
+LRE+ + N+ +P++G S N+ +L+L N + ++ ++ + +L L L
Sbjct: 39 SLREVKLNNNELETIPNLGPVS----ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 94
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F L LK L L +N+++++ F LA L +L L+ N ++ + P++F
Sbjct: 95 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 152
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
K +QHL + R ++ ++ + + L+ L + N L F L ++ L+
Sbjct: 153 KLPQLQHLEL---NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 209
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
LD N L+ I L L LS+N D++ N + R
Sbjct: 210 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDS 269
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEH 374
+F + L T++ GNN + L + + L N + E F+ +
Sbjct: 270 SFLGL-SLLNTLHI-GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDK 327
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N++ K + L+ LD+S N + +L +++ + +++L ++
Sbjct: 328 LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 387
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLS 476
CD C + ++ S + C P L+G + ++S
Sbjct: 388 CD-CQLKWLPQWVAENNFQSFVNA-SCAHPQLLKGRSIFAVS 427
Score = 73.7 bits (173), Expect = 2e-12
Identities = 72/306 (23%), Positives = 136/306 (44%), Gaps = 12/306 (3%)
Query: 130 LINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
L +++ L HN + + + + HL SL+ + L NN++ T + L + A +++L L+ N
Sbjct: 13 LFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGN 71
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFIS 249
+ ++ PE K+ Q L + + T L +L+ L L N + F +
Sbjct: 72 RIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL--QLKYLYLNSNRVTSMEPGYFDN 129
Query: 250 L-KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISH 308
L L LKL+ N++S I MF + +L L L+RN+ +
Sbjct: 130 LANTLLVLKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQR 188
Query: 309 NKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQ 366
N + + F + +++ + NNL L +L E+H L+ ++ I
Sbjct: 189 NGVTKLMDGAFWG-LSNMEILQLDHNNLTEITKGWLYGLLMLQELH---LSQNAINRISP 244
Query: 367 NFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
+ + + + L LDL++N LSR L L I +N++ +++ + L ++ +
Sbjct: 245 DAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTL 304
Query: 427 NLMKNN 432
+L KNN
Sbjct: 305 DL-KNN 309
Score = 67.7 bits (158), Expect = 1e-10
Identities = 61/231 (26%), Positives = 102/231 (44%), Gaps = 4/231 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN-LTELHLDH 140
F +L L + ++N+ + Q +F LQ L+ L L N +TS+ F L N L L L+
Sbjct: 84 FQSLETLDLSSNNISEL-QTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNR 141
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I + + F+ L L+ L L N+I + F+ L L L + N +T L F
Sbjct: 142 NRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFW 200
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+ ++ I + L I + + L+EL L +N ++ D + ++L +L L
Sbjct: 201 GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTF 260
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
N LS + D+ F L+ L + NR D+ +N+I
Sbjct: 261 NHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEI 311
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 85.4 bits (202), Expect = 5e-16
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 29/207 (14%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L + + V + +FWGL N+ +L L HNNLT + GL+ L ELHL N I
Sbjct: 241 LKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAIN 300
Query: 145 QMSSE-------------TFRHLTS-----------LKTLILANNQISTLVSRLFRMLAK 180
++S + TF HL+ L TL + NN++S + FR L+
Sbjct: 301 RISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSS 360
Query: 181 LSILDLSDNPLT----DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGE 236
L LDL +N ++ D+N F + LR + +R I + + + LE LDL +
Sbjct: 361 LKTLDLKNNEISWTIEDMN-GAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 237 NLFKYLTSDEFISLKRLKKLKLDGNQL 263
N L + F +K+L++L L+ + L
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 78.6 bits (185), Expect = 5e-14
Identities = 89/402 (22%), Positives = 175/402 (43%), Gaps = 22/402 (5%)
Query: 84 NLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
+LRE+ + N+ +P++G S N+ +L+L N + ++ ++ + +L L L
Sbjct: 99 SLREVKLNNNELETIPNLGPVS----ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 154
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVF 199
N+I ++ + F L LK L L +N+++++ F LA L +L L+ N ++ + P++F
Sbjct: 155 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 212
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
K +QHL + R ++ ++ + + L+ L + N L F L ++ L+
Sbjct: 213 KLPQLQHLEL---NRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 269
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
LD N L+ I L L LS+N D++ N + R
Sbjct: 270 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDS 329
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ---EIPQNFFTYNEH 374
+F + L T++ GNN + L + + L N + E F+ +
Sbjct: 330 SFLGL-SLLNTLHI-GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDK 387
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N++ K + L+ LD+S N + +L +++ + +++L ++
Sbjct: 388 LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLS 476
CD C + ++ S + C P L+G + ++S
Sbjct: 448 CD-CQLKWLPQWVAENNFQSFVNA-SCAHPQLLKGRSIFAVS 487
Score = 73.7 bits (173), Expect = 2e-12
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 12/303 (3%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ L L HN + + + + HL SL+ + L NN++ T + L + A +++L L+ N +
Sbjct: 76 VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRIV 134
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL-K 251
++ PE K+ Q L + + T L +L+ L L N + F +L
Sbjct: 135 EILPEHLKEFQSLETLDLSSNNISELQTAFPAL--QLKYLYLNSNRVTSMEPGYFDNLAN 192
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
L LKL+ N++S I MF + +L L L+RN+ + N +
Sbjct: 193 TLLVLKLNRNRISAIPPKMF-KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGV 251
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIVLQILPEIHGVGLANLSLQEIPQNFF 369
+ F + +++ + NNL L +L E+H L+ ++ I + +
Sbjct: 252 TKLMDGAFWG-LSNMEILQLDHNNLTEITKGWLYGLLMLQELH---LSQNAINRISPDAW 307
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ + L LDL++N LSR L L I +N++ +++ + L ++ ++L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDL- 366
Query: 430 KNN 432
KNN
Sbjct: 367 KNN 369
Score = 67.7 bits (158), Expect = 1e-10
Identities = 61/231 (26%), Positives = 102/231 (44%), Gaps = 4/231 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN-LTELHLDH 140
F +L L + ++N+ + Q +F LQ L+ L L N +TS+ F L N L L L+
Sbjct: 144 FQSLETLDLSSNNISEL-QTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNR 201
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N I + + F+ L L+ L L N+I + F+ L L L + N +T L F
Sbjct: 202 NRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFW 260
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
+ ++ I + L I + + L+EL L +N ++ D + ++L +L L
Sbjct: 261 GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTF 320
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
N LS + D+ F L+ L + NR D+ +N+I
Sbjct: 321 NHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEI 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LD S +L+R P L S ++ RLD+SHN+L + + L+++ EV L N
Sbjct: 58 LDCSRKRLARLPEPLPS---WVARLDLSHNRLSFIKASSMSHLQSLREVKLNNN 108
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 85.4 bits (202), Expect = 5e-16
Identities = 92/379 (24%), Positives = 153/379 (40%), Gaps = 11/379 (2%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
+ L+++ NN+T + D F+ L EL L N + + + L LK L L NNQ+ T
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ S R L+ L L L N +T + + F+ + LR L + +P L
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
+ L L N + F +L L L L N++ + + F L L LS N
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQIL 348
S N I F L+TI+ N PL+ + L
Sbjct: 240 FPQAIKARPSLKELGFHS-NSISVIPDGAFDGN-PLLRTIHLYDN--PLSFVGNSASHNL 295
Query: 349 PEIHGVGLANLSL-QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
++H + + S+ Q+ P T HL +L L+ K+S P L + K L+ LD+S+N
Sbjct: 296 SDLHSLVIRGASMVQQFPN--LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 353
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNN-WHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLR 466
++ L A+ E++L +N + + + ++ + + I + +
Sbjct: 354 NIRDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFAT 411
Query: 467 LRGATFGSLSFEQLDPCPT 485
L T +SF +L PT
Sbjct: 412 LGPITNLDVSFNELTSFPT 430
Score = 82.2 bits (194), Expect = 4e-15
Identities = 85/358 (23%), Positives = 141/358 (39%), Gaps = 9/358 (2%)
Query: 76 FTQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
F P L+EL ++ N+ + ++ + GL L+ L L N++TSV D+F GL+
Sbjct: 95 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 154
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
L L LD N + ++ +L +L+ L LA N+IS++ F L+ L +L L +N +
Sbjct: 155 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 214
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
L+ F + +L L Q P L+EL N + F
Sbjct: 215 GLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSISVIPDGAFDGNPL 273
Query: 253 LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKID 312
L+ + L N LS + ++ +LH L + R ++ KI
Sbjct: 274 LRTIHLYDNPLSFVGNSASHNLSDLHSLVI-RGASMVQQFPNLTGTVHLESLTLTGTKIS 332
Query: 313 RFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYN 372
L+T++ S NN+ L EI L + +I + F
Sbjct: 333 SIP-NNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEI---SLQRNQIYQIKEGTFQGL 388
Query: 373 EHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMK 430
L LDLS N + + + + LD+S N+L + + L + V K
Sbjct: 389 ISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPNGLNQLKLVGNFK 446
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 3/205 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
F L EL + +++ I + GL+ L+VL L +N L +V ++ RGL L L LD N
Sbjct: 80 FPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDAN 139
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
HI + ++F L L+ L L +N ++ + L L L L+ N ++ + F +
Sbjct: 140 HITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTN 199
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFISLKRLKKLKLDG 260
+ L + +R ++ + + LE LDL NL ++ + LK+L
Sbjct: 200 LSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF--PQAIKARPSLKELGFHS 257
Query: 261 NQLSVIVDNMFGRNRELHVLTLSRN 285
N +SVI D F N L + L N
Sbjct: 258 NSISVIPDGAFDGNPLLRTIHLYDN 282
Score = 61.7 bits (143), Expect = 7e-09
Identities = 74/347 (21%), Positives = 135/347 (38%), Gaps = 6/347 (1%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L I +N+ + + +F L L L N+L+ + GL L L L +N ++ +
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
SE R L++L++L L N I+++ F L +L L L DN LT++ ++ L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIV 267
+ I + + L L L N + L+ F L L+ L L N L
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFP 241
Query: 268 DNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLK 327
+ R L L N + N + F + + + L
Sbjct: 242 QAIKAR-PSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS-FVGNSASHNLSDLH 299
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
++ G ++ + + + + L + IP N + L LDLS+N +
Sbjct: 300 SLVIRGASMVQQFPNLTGTV--HLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRD 357
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
P + L+ + + N++ + E Q L ++ ++L +N H
Sbjct: 358 LP--SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/135 (31%), Positives = 67/135 (49%), Gaps = 5/135 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L L + + + SI + LR L+L++NN+ + +F G L E+ L N
Sbjct: 319 VHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQRNQ 376
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I Q+ TF+ L SL+ L L+ N I + SR F L ++ LD+S N LT E +
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPNGL 436
Query: 203 QHLRI---FKCRRCL 214
L++ FK + L
Sbjct: 437 NQLKLVGNFKLKEAL 451
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V + L +P+ + + ALD+S N +++ P FL+ L ++ N L +
Sbjct: 41 VDCSGKGLTAVPEGLSAFTQ---ALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH 97
Query: 414 EQDLQRLEAIAEVNLMKN 431
+ L L+ + + L N
Sbjct: 98 PKALSGLKELKVLTLQNN 115
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 83.8 bits (198), Expect = 1e-15
Identities = 82/363 (22%), Positives = 155/363 (42%), Gaps = 11/363 (3%)
Query: 72 IGPIFTQPAPFVN-LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
I + P P ++ L EL + + + I + +F GL +L+VL L +N L V + + L
Sbjct: 78 ISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L L LD NHI + F L SL+ L L +N ++ + + FR L+ L + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG-ENLFKYLTSDEFIS 249
+ + F ++ + + + + + + LE LDL NL ++ T+ +
Sbjct: 198 IHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIR--T 255
Query: 250 LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISH- 308
L LK+L N + I + F N L + N ++
Sbjct: 256 LSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGA 315
Query: 309 NKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNF 368
++I F T ++SL ++LP V LP + + L+ L+++P
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQT----VCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 369 FTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNL 428
F+ + L +DL N++ + L+ L+++ NK+ + L ++ +++L
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDL 429
Query: 429 MKN 431
N
Sbjct: 430 SSN 432
Score = 82.2 bits (194), Expect = 4e-15
Identities = 87/340 (25%), Positives = 146/340 (42%), Gaps = 7/340 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + +++ + F GL +LR L L N LT + FR L L + L N I
Sbjct: 139 SLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI 198
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F +L+S L L NN+I +L + F L L LDL+ N L + P + +
Sbjct: 199 HHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLS 257
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L+ +R I + + P L + +N +++ F L L+ L L+G
Sbjct: 258 NLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQ 317
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
++ G L LTL+ + D+S+N ++ L +F+ V
Sbjct: 318 ITEFPDLTG-TANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFS-VC 373
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L+ I+ N + ++ Q+L + + LA + I N F+ L+ LDLS N
Sbjct: 374 QKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
LS FP L L +L +H +S ++ L+ I
Sbjct: 433 LLSSFPITGLHGLTHL-KLTGNHALQSLISSENFPELKVI 471
Score = 74.9 bits (176), Expect = 7e-13
Identities = 74/328 (22%), Positives = 137/328 (41%), Gaps = 6/328 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + N+ + + + L++L+ L L N+++ V F GL +L L LD N +
Sbjct: 115 SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNAL 174
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + FR L++L+ + LA N+I + F L+ +L L +N + L + F +
Sbjct: 175 TEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLH 234
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L L T I + L+EL N + + F+ L + N +
Sbjct: 235 SLETLDLNYNNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPI 293
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
+ + F EL LTL+ ++ +I QT +
Sbjct: 294 QFVGRSAFQHLPELRTLTLN-GASQITEFPDLTGTANLESLTLTGAQISSLP-QTVCNQL 351
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
+L+ ++ S N L E + ++ + L + + EI + F L +L+L+WN
Sbjct: 352 PNLQVLDLSYN---LLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408
Query: 384 KLSRFPFKLLSKTKFLQRLDISHNKLQT 411
K++ S L +LD+S N L +
Sbjct: 409 KIAIIHPNAFSTLPSLIKLDLSSNLLSS 436
Score = 72.9 bits (171), Expect = 3e-12
Identities = 82/315 (26%), Positives = 132/315 (41%), Gaps = 9/315 (2%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L+ NN++ ++ + L L EL L N + + F L SLK L+L NNQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ + L L L L N ++ + P F + LR L I Q + + L+
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
+ L N ++ F +L L L N++ + F L L L+ N
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIA-IVLQILPE 350
S+N I + F SL TI+F N P+ + Q LPE
Sbjct: 251 TAIRTLSNLKELGFHSNN-IRSIPEKAFVG-NPSLITIHFYDN--PIQFVGRSAFQHLPE 306
Query: 351 IHGVGLANLS-LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L S + E P T +L +L L+ ++S P + ++ LQ LD+S+N L
Sbjct: 307 LRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLL 364
Query: 410 QTL-SEQDLQRLEAI 423
+ L S Q+L+ I
Sbjct: 365 EDLPSFSVCQKLQKI 379
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V ++L L E+P N + +L DLS N +S+ L FL+ L ++ N L +
Sbjct: 50 VDCSDLGLSELPSNLSVFTSYL---DLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIP 106
Query: 414 EQDLQRLEAIAEVNLMKNN 432
+ L ++ +V +++NN
Sbjct: 107 KGAFTGLYSL-KVLMLQNN 124
>BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat
containing 33 protein.
Length = 692
Score = 83.4 bits (197), Expect = 2e-15
Identities = 88/333 (26%), Positives = 145/333 (43%), Gaps = 17/333 (5%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L L N L ++ + + L L L H+E++S F+ L++L+L +N +S
Sbjct: 60 RMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSE 119
Query: 170 L---VSRLFRMLAKLSILDLSDNPLT-DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
+ L L LDLS N LT D+ + +++ LR + R++ ++
Sbjct: 120 NYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEG 179
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ RL ELDL N + F L L+ L L N L IVD FG R L VL +S N
Sbjct: 180 LERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVD--FGLTR-LRVLNVSYN 236
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL----PLNEI 341
D+SHN++ F L P L+T+ NN+ L
Sbjct: 237 VLEWFLATGGEAAFELETLDLSHNQLLFFPL---LPQYSKLRTLLLRDNNMGFYRDLYNT 293
Query: 342 AIVLQILPEIHGV--GLANLSLQEIPQNFFTYN-EHLVALDLSWNKLSRFPFKLLSKTKF 398
+ +++ + V + N++ + + F + + L LD+S N+ P L K
Sbjct: 294 SSPREMVAQFLLVDGNVTNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPS 353
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L L++ N L TL ++ + A+ E++L N
Sbjct: 354 LSHLNLHQNCLMTLHIREHEPPGALTELDLSHN 386
Score = 53.2 bits (122), Expect = 2e-06
Identities = 74/307 (24%), Positives = 123/307 (40%), Gaps = 20/307 (6%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L++ +N+P I F GL LRVLN+++N L +A L L L HN +
Sbjct: 207 LRHLNLAFNNLPCIVDF---GLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQL- 262
Query: 145 QMSSETFRHLTSLKTLILANNQISTL-----VSRLFRMLAKLSILDLSDNPLTDLNP-EV 198
+ + L+TL+L +N + S M+A+ ++D + +T ++ E
Sbjct: 263 -LFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNVTNITTVSLWEE 321
Query: 199 F--KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
F D+ LR + + + +P L L+L +N L E L +L
Sbjct: 322 FSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTEL 381
Query: 257 KLDGNQLSV--IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L NQLS + + L + LS N+ D+SHN+I
Sbjct: 382 DLSHNQLSELHLAPGLASCLGSLRLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISLC 441
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIV---LQILPEIHGVGLANLSLQEIPQNFFTY 371
L + V ++F N L +++ L LP+ G +L+ ++ N+
Sbjct: 442 PLPAASDRVGPPSCVDFR-NMASLRSLSLEGCGLGALPDCPFQG-TSLTYLDLSSNWGVL 499
Query: 372 NEHLVAL 378
N L L
Sbjct: 500 NGSLAPL 506
Score = 46.4 bits (105), Expect = 3e-04
Identities = 73/284 (25%), Positives = 112/284 (39%), Gaps = 35/284 (12%)
Query: 85 LRELHIV-NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
LR L + N+ + L +LR ++L N + + F GL L EL L N+I
Sbjct: 134 LRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYI 193
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP----LTDLNPEVF 199
++ F L L+ L LA N + +V F L +L +L++S N L F
Sbjct: 194 FEIEGGAFDGLAELRHLNLAFNNLPCIVD--FG-LTRLRVLNVSYNVLEWFLATGGEAAF 250
Query: 200 K----DIQHLRIF---------KCRRCLLRRINTQIYHLV-----PR--LEELDLGENLF 239
+ D+ H ++ K R LLR N Y + PR + + L +
Sbjct: 251 ELETLDLSHNQLLFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNV 310
Query: 240 KYLTS----DEFIS--LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXX 293
+T+ +EF S L L+ L + NQ + D + L L L +N
Sbjct: 311 TNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIR 370
Query: 294 XXXXXXXXXXXDISHNKIDRFHLQT-FAPVVDSLKTINFSGNNL 336
D+SHN++ HL A + SL+ N S N L
Sbjct: 371 EHEPPGALTELDLSHNQLSELHLAPGLASCLGSLRLFNLSSNQL 414
>AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein.
Length = 692
Score = 83.4 bits (197), Expect = 2e-15
Identities = 88/333 (26%), Positives = 145/333 (43%), Gaps = 17/333 (5%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L L N L ++ + + L L L H+E++S F+ L++L+L +N +S
Sbjct: 60 RMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSE 119
Query: 170 L---VSRLFRMLAKLSILDLSDNPLT-DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
+ L L LDLS N LT D+ + +++ LR + R++ ++
Sbjct: 120 NYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEG 179
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ RL ELDL N + F L L+ L L N L IVD FG R L VL +S N
Sbjct: 180 LERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVD--FGLTR-LRVLNVSYN 236
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL----PLNEI 341
D+SHN++ F L P L+T+ NN+ L
Sbjct: 237 VLEWFLATGGEAAFELETLDLSHNQLLFFPL---LPQYSKLRTLLLRDNNMGFYRDLYNT 293
Query: 342 AIVLQILPEIHGV--GLANLSLQEIPQNFFTYN-EHLVALDLSWNKLSRFPFKLLSKTKF 398
+ +++ + V + N++ + + F + + L LD+S N+ P L K
Sbjct: 294 SSPREMVAQFLLVDGNVTNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPS 353
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L L++ N L TL ++ + A+ E++L N
Sbjct: 354 LSHLNLHQNCLMTLHIREHEPPGALTELDLSHN 386
Score = 53.2 bits (122), Expect = 2e-06
Identities = 74/307 (24%), Positives = 123/307 (40%), Gaps = 20/307 (6%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L++ +N+P I F GL LRVLN+++N L +A L L L HN +
Sbjct: 207 LRHLNLAFNNLPCIVDF---GLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQL- 262
Query: 145 QMSSETFRHLTSLKTLILANNQISTL-----VSRLFRMLAKLSILDLSDNPLTDLNP-EV 198
+ + L+TL+L +N + S M+A+ ++D + +T ++ E
Sbjct: 263 -LFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNVTNITTVSLWEE 321
Query: 199 F--KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
F D+ LR + + + +P L L+L +N L E L +L
Sbjct: 322 FSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTEL 381
Query: 257 KLDGNQLSV--IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L NQLS + + L + LS N+ D+SHN+I
Sbjct: 382 DLSHNQLSELHLAPGLASCLGSLRLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISLC 441
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIV---LQILPEIHGVGLANLSLQEIPQNFFTY 371
L + V ++F N L +++ L LP+ G +L+ ++ N+
Sbjct: 442 PLPAASDRVGPPSCVDFR-NMASLRSLSLEGCGLGALPDCPFQG-TSLTYLDLSSNWGVL 499
Query: 372 NEHLVAL 378
N L L
Sbjct: 500 NGSLAPL 506
Score = 46.4 bits (105), Expect = 3e-04
Identities = 73/284 (25%), Positives = 112/284 (39%), Gaps = 35/284 (12%)
Query: 85 LRELHIV-NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
LR L + N+ + L +LR ++L N + + F GL L EL L N+I
Sbjct: 134 LRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYI 193
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP----LTDLNPEVF 199
++ F L L+ L LA N + +V F L +L +L++S N L F
Sbjct: 194 FEIEGGAFDGLAELRHLNLAFNNLPCIVD--FG-LTRLRVLNVSYNVLEWFLATGGEAAF 250
Query: 200 K----DIQHLRIF---------KCRRCLLRRINTQIYHLV-----PR--LEELDLGENLF 239
+ D+ H ++ K R LLR N Y + PR + + L +
Sbjct: 251 ELETLDLSHNQLLFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNV 310
Query: 240 KYLTS----DEFIS--LKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXX 293
+T+ +EF S L L+ L + NQ + D + L L L +N
Sbjct: 311 TNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIR 370
Query: 294 XXXXXXXXXXXDISHNKIDRFHLQT-FAPVVDSLKTINFSGNNL 336
D+SHN++ HL A + SL+ N S N L
Sbjct: 371 EHEPPGALTELDLSHNQLSELHLAPGLASCLGSLRLFNLSSNQL 414
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 83.0 bits (196), Expect = 3e-15
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L++ + + I SF L++L +L L+ N++ ++ F G N L L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRL 136
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ + F +L+ LK L L NN I ++ S F + L LDL + L+ ++ F+ +
Sbjct: 137 ATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR C LR I + L+ +L+ELDL N + F L L+KL + +Q
Sbjct: 197 SNLRYLNLAMCNLREI-PNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQ 254
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+ VI N F + L + L+ N
Sbjct: 255 IRVIERNAFDNLQSLVEINLAHN 277
Score = 61.3 bits (142), Expect = 9e-09
Identities = 70/273 (25%), Positives = 118/273 (43%), Gaps = 22/273 (8%)
Query: 4 LVVYNTEAAGTICPDECTCTMTFD-----------LEEGHTTQVACQHGH---MRIIPVD 49
LVV A T CP C+C+ F + +G +T + H ++II V+
Sbjct: 36 LVVAGLVRAQT-CPSVCSCSNQFSKVICVRKNLRGVPDGISTNTRLLNLHENQIQIIKVN 94
Query: 50 YMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNL 109
H+ I+ + + IG F PA N L + ++ + +I +F L L
Sbjct: 95 SFKHLRHLEILQLSRNHIRTIEIGA-FNGPA---NPNTLELFDNRLATIPNGAFVYLSKL 150
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDH-NHIEQMSSETFRHLTSLKTLILANNQIS 168
+ L L +N + S+ + F + +L L L + +S F L++L+ L LA +
Sbjct: 151 KELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLR 210
Query: 169 TLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPR 228
+ + L KL LDLS N L+ + P F+ + HL+ + +R I + +
Sbjct: 211 EIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRVIERNAFDNLQS 268
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L E++L N L D F L L+++ L N
Sbjct: 269 LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 56.8 bits (131), Expect = 2e-07
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 3/225 (1%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+L+L +N + + FK ++HL I + R +R I ++ L+L +N +
Sbjct: 80 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLATI 139
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
+ F+ L +LK+L L N + I F R L L L +
Sbjct: 140 PNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNL 199
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
++ + + P++ L ++ SGN+L Q L + + + ++
Sbjct: 200 RY-LNLAMCNLREIPNLTPLI-KLDELDLSGNHLSAIRPGS-FQGLMHLQKLWMIQSQIR 256
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
I +N F + LV ++L+ N L+ P L + L+R+ + HN
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 48.8 bits (111), Expect = 5e-05
Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ N+ I + L L L+L+ N+L+++ +F+GL++L +L + + I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F +L SL + LA+N ++ L LF L L + L NP
Sbjct: 256 RVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
Score = 41.5 bits (93), Expect = 0.008
Identities = 51/270 (18%), Positives = 101/270 (37%), Gaps = 4/270 (1%)
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV 265
R+ ++ I + + LE L L N + + F L+L N+L+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLAT 138
Query: 266 IVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS 325
I + F +L L L N D+ K + + + +
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 326 LKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
L+ +N + NL EI + ++ ++ + L+ L I F HL L + +++
Sbjct: 199 LRYLNLAMCNL--REIPNLTPLI-KLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 386 SRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLL 445
+ L ++++HN L L L + ++L N W+C+ C +
Sbjct: 256 RVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSW 314
Query: 446 YMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ ++T +C++P L+G G L
Sbjct: 315 WIKDMAPSNTACCARCNTPPNLKGRYIGEL 344
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 83.0 bits (196), Expect = 3e-15
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ C ++ + + LV LEEL++ N F + F L LKKL + +Q
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+S+I N F L L L+ N
Sbjct: 254 VSLIERNAFDGLASLVELNLAHN 276
Score = 60.9 bits (141), Expect = 1e-08
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+Q+S + F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 56.0 bits (129), Expect = 3e-07
Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 30/287 (10%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N + ++ R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSQVSLIE-------RNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 291
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L N W+CD C + ++ + ++ +CH+P+ +RG
Sbjct: 292 LVELHLHHNPWNCD-CDILWLAWWLREYIPTNSTCCGRCHAPMHMRG 337
Score = 52.4 bits (120), Expect = 4e-06
Identities = 28/58 (48%), Positives = 38/58 (65%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS V I + +F GL +L LNL HNNL+S+ D F L L ELHL HN
Sbjct: 243 SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/85 (32%), Positives = 47/85 (55%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + ++ ++ + + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 141 NHIEQMSSETFRHLTSLKTLILANN 165
N++ + + F L L L L +N
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++ +
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQV 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F L SL L LA+N +S+L LF L L L L NP
Sbjct: 255 SLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 301
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 83.0 bits (196), Expect = 3e-15
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ C ++ + + LV LEEL++ N F + F L LKKL + +Q
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+S+I N F L L L+ N
Sbjct: 254 VSLIERNAFDGLASLVELNLAHN 276
Score = 60.9 bits (141), Expect = 1e-08
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+Q+S + F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 56.0 bits (129), Expect = 3e-07
Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 30/287 (10%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N + ++ R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSQVSLIE-------RNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 291
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L N W+CD C + ++ + ++ +CH+P+ +RG
Sbjct: 292 LVELHLHHNPWNCD-CDILWLAWWLREYIPTNSTCCGRCHAPMHMRG 337
Score = 52.4 bits (120), Expect = 4e-06
Identities = 28/58 (48%), Positives = 38/58 (65%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS V I + +F GL +L LNL HNNL+S+ D F L L ELHL HN
Sbjct: 243 SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/85 (32%), Positives = 47/85 (55%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + ++ ++ + + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 141 NHIEQMSSETFRHLTSLKTLILANN 165
N++ + + F L L L L +N
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++ +
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQV 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F L SL L LA+N +S+L LF L L L L NP
Sbjct: 255 SLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 301
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 83.0 bits (196), Expect = 3e-15
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ C ++ + + LV LEEL++ N F + F L LKKL + +Q
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+S+I N F L L L+ N
Sbjct: 254 VSLIERNAFDGLASLVELNLAHN 276
Score = 60.9 bits (141), Expect = 1e-08
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+Q+S + F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 56.0 bits (129), Expect = 3e-07
Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 30/287 (10%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N + ++ R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSQVSLIE-------RNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 291
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L N W+CD C + ++ + ++ +CH+P+ +RG
Sbjct: 292 LVELHLHHNPWNCD-CDILWLAWWLREYIPTNSTCCGRCHAPMHMRG 337
Score = 52.4 bits (120), Expect = 4e-06
Identities = 28/58 (48%), Positives = 38/58 (65%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS V I + +F GL +L LNL HNNL+S+ D F L L ELHL HN
Sbjct: 243 SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/85 (32%), Positives = 47/85 (55%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + ++ ++ + + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 141 NHIEQMSSETFRHLTSLKTLILANN 165
N++ + + F L L L L +N
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++ +
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQV 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F L SL L LA+N +S+L LF L L L L NP
Sbjct: 255 SLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 301
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 83.0 bits (196), Expect = 3e-15
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ C ++ + + LV LEEL++ N F + F L LKKL + +Q
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+S+I N F L L L+ N
Sbjct: 254 VSLIERNAFDGLASLVELNLAHN 276
Score = 60.9 bits (141), Expect = 1e-08
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+Q+S + F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 53.2 bits (122), Expect = 2e-06
Identities = 61/287 (21%), Positives = 119/287 (41%), Gaps = 30/287 (10%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N + ++ R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSQVSLIE-------RNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 291
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L + W+CD C + + + ++ +CH+P+ +RG
Sbjct: 292 LVELHLHHDPWNCD-CDILWLAWWFREYIPTNSTCCGRCHAPMHMRG 337
Score = 50.4 bits (115), Expect = 2e-05
Identities = 27/58 (46%), Positives = 38/58 (65%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS V I + +F GL +L LNL HNNL+S+ D F L L ELHL H+
Sbjct: 243 SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHD 300
Score = 48.8 bits (111), Expect = 5e-05
Identities = 27/82 (32%), Positives = 45/82 (54%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + ++ ++ + + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 141 NHIEQMSSETFRHLTSLKTLIL 162
N++ + + F L L L L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 41.5 bits (93), Expect = 0.008
Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++ +
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQV 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F L SL L LA+N +S+L LF L L L L +P
Sbjct: 255 SLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHDP 301
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 83.0 bits (196), Expect = 3e-15
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ C ++ + + LV LEEL++ N F + F L LKKL + +Q
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
+S+I N F L L L+ N
Sbjct: 254 VSLIERNAFDGLASLVELNLAHN 276
Score = 60.9 bits (141), Expect = 1e-08
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+Q+S + F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 56.0 bits (129), Expect = 3e-07
Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 30/287 (10%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N + ++ R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSQVSLIE-------RNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 291
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L N W+CD C + ++ + ++ +CH+P+ +RG
Sbjct: 292 LVELHLHHNPWNCD-CDILWLAWWLREYIPTNSTCCGRCHAPMHMRG 337
Score = 52.4 bits (120), Expect = 4e-06
Identities = 28/58 (48%), Positives = 38/58 (65%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS V I + +F GL +L LNL HNNL+S+ D F L L ELHL HN
Sbjct: 243 SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/85 (32%), Positives = 47/85 (55%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + ++ ++ + + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 141 NHIEQMSSETFRHLTSLKTLILANN 165
N++ + + F L L L L +N
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++ +
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQV 254
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ F L SL L LA+N +S+L LF L L L L NP
Sbjct: 255 SLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 301
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 82.6 bits (195), Expect = 3e-15
Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 2/202 (0%)
Query: 85 LRELHIVNSNVPSIGQFSFWGL-QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++EL++ + + ++ +F GL ++L L L+ N +T + F+ L LT+L L+ N I
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRI 223
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ TF+ L SL+ L L N IS L F L+K+ +L L N L ++N +
Sbjct: 224 RLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLT 283
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + RI+ + + +L EL L N L + L L L+L N +
Sbjct: 284 ALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
S I + F R L VL L N
Sbjct: 344 SHIAEGAFKGLRSLRVLDLDHN 365
Score = 80.6 bits (190), Expect = 1e-14
Identities = 77/303 (25%), Positives = 131/303 (43%), Gaps = 7/303 (2%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L++ + I F L NL+ + L +N LT+V + ++ L L HN I
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASS-HVVSLFLQHNKIRS 129
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI-QH 204
+ + SL+ L L+ N I+ + + F + L+L+ N + L F + +
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L + + + ++ + + L PRL +LDL N + + F L L+ LKL N +S
Sbjct: 190 LLTLRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 265 VIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVD 324
+ D F ++HVL L N +S+N I R H + ++
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWS-FCQ 307
Query: 325 SLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWN 383
L + S NNL L+E + L L + + L++ S+ I + F L LDL N
Sbjct: 308 KLHELVLSFNNLTRLDEES--LAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHN 365
Query: 384 KLS 386
++S
Sbjct: 366 EIS 368
Score = 71.7 bits (168), Expect = 6e-12
Identities = 53/177 (29%), Positives = 84/177 (47%), Gaps = 3/177 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L +L + + + I +F GL +L VL L NN++ + F GL + LHL++N +
Sbjct: 213 LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLV 272
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+++S + LT+L L L+NN I+ + + + KL L LS N LT L+ E ++
Sbjct: 273 EVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSS 332
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL---TSDEFISLKRLKKLKL 258
L + + + I + + L LDL N TS F L L KL L
Sbjct: 333 LSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLL 389
Score = 71.3 bits (167), Expect = 8e-12
Identities = 37/124 (29%), Positives = 67/124 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L + +N+ + +FWGL + VL+L +N+L V + + GL L +LHL +N I
Sbjct: 236 SLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSI 295
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ + + L L+L+ N ++ L L+ LS+L LS N ++ + FK ++
Sbjct: 296 ARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLR 355
Query: 204 HLRI 207
LR+
Sbjct: 356 SLRV 359
Score = 68.1 bits (159), Expect = 8e-11
Identities = 91/345 (26%), Positives = 137/345 (39%), Gaps = 61/345 (17%)
Query: 69 FLTIGPIFTQPAPFVNLRELHIVNSN---VPSIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
F I P + P NL+E+++ N+ VPS+G S ++ L L HN + SV
Sbjct: 80 FSEIDPAGFEDLP--NLQEVYLNNNELTAVPSLGAAS----SHVVSLFLQHNKIRSVEGS 133
Query: 126 NFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAK-LSIL 184
+ ++L L L N+I ++ + F H +K L LA N+I TL F L++ L L
Sbjct: 134 QLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTL 193
Query: 185 DLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTS 244
LS N +T L FK +PRL +LDL N + +
Sbjct: 194 RLSKNRITQLPVRAFK-------------------------LPRLTQLDLNRNRIRLIEG 228
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L L+ LKL N +S + D F ++HVL L N
Sbjct: 229 LTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQL 288
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+S+N I R H + ++ F L+E+ + L + LA LS
Sbjct: 289 HLSNNSIARIHRKGWS----------FCQK---LHELVLSFNNLTRLDEESLAELS---- 331
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
L L LS N +S + L+ LD+ HN++
Sbjct: 332 ---------SLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Score = 63.7 bits (148), Expect = 2e-09
Identities = 80/325 (24%), Positives = 141/325 (43%), Gaps = 33/325 (10%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS--ETFRHLTSLKTLILANNQI 167
R LNL++N + + F L NL E++L++N + + S H+ SL L +N+I
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSL---FLQHNKI 127
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
++ + L +LDLS N +T++ F ++ + + + +
Sbjct: 128 RSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLS 187
Query: 228 R-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
R L L L +N L F L RL +L L+ N++ +I F L VL L RN
Sbjct: 188 RSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNN 246
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQ 346
+K+ HL+ +SL +N SG+ L
Sbjct: 247 ISKLTDGAFWGL----------SKMHVLHLE-----YNSLVEVN-SGS----------LY 280
Query: 347 ILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISH 406
L +H + L+N S+ I + +++ + L L LS+N L+R + L++ L L +SH
Sbjct: 281 GLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSH 340
Query: 407 NKLQTLSEQDLQRLEAIAEVNLMKN 431
N + ++E + L ++ ++L N
Sbjct: 341 NSISHIAEGAFKGLRSLRVLDLDHN 365
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 9/183 (4%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L +LH+ N+++ I + + Q L L L+ NNLT + ++ L +L+ L L HN I
Sbjct: 285 LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSIS 344
Query: 145 QMSSETFRHLTSLKTLILANNQISTLV---SRLFR---MLAKLSILDLSDNPLTDLNPEV 198
++ F+ L SL+ L L +N+IS + S F L+KL +L+ S + +
Sbjct: 345 HIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLLLEPSQSAGCSSPSQP 404
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+F + ++ + + + + LE L+LG N + + D F+ +K LK+L +
Sbjct: 405 HMSAGGRTLFGNK---IKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHI 461
Query: 259 DGN 261
+
Sbjct: 462 SSD 464
Score = 50.4 bits (115), Expect = 2e-05
Identities = 37/131 (28%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---FRGLINLTE- 135
A +L L + ++++ I + +F GL++LRVL+L HN ++ + D F GL +L++
Sbjct: 328 AELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKL 387
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L+ + SS + H+ S L N+I ++ R F L L L+L N + +
Sbjct: 388 LLLEPSQSAGCSSPSQPHM-SAGGRTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQ 446
Query: 196 PEVFKDIQHLR 206
+ F +++L+
Sbjct: 447 FDAFVKMKNLK 457
Score = 34.3 bits (75), Expect = 1.2
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L+L N F + F L L+++ L+ N+L+ V ++ + + L L N+
Sbjct: 73 LNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTA-VPSLGAASSHVVSLFLQHNKIRSVE 131
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D+S N I F P +K +N +GN + E+
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCF-PHGPPIKELNLAGNRIGTLELGA-------- 182
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
F + L+ L LS N++++ P + K L +LD++ N+++
Sbjct: 183 ----------------FDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIRL 225
Query: 412 LSEQDLQRLEAIAEVNLMKNN 432
+ Q L ++ + L +NN
Sbjct: 226 IEGLTFQGLNSLEVLKLQRNN 246
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 80.2 bits (189), Expect = 2e-14
Identities = 91/334 (27%), Positives = 152/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ L HL+ N
Sbjct: 263 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL---HLEKN 319
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 320 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 379
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 380 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 436
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L ++ G R +HVL + RN ++ N++ L
Sbjct: 437 LSGNRLHMLPP---GLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALG 493
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 494 PRAWVDLAHLQLLDIAGNQ--LTEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 548
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 549 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 582
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 18/261 (6%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
NLR +++ N+ + G F G N+ VL L+ N L V L +LHL +N
Sbjct: 192 NLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNN 248
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+E++ F L+SL+ L L NN ++ L + F L+ L LDLS N L+ + +
Sbjct: 249 KLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP 308
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLK 257
+ + L + + +R ++ + + LE L L N + + F LKRL +
Sbjct: 309 RSLVLLHL---EKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVH 365
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFH 315
L N L + G R + L + N+ ++S+N+I + H
Sbjct: 366 LYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 422
Query: 316 LQTFAPVVDSLKTINFSGNNL 336
F + L++++ SGN L
Sbjct: 423 RDAFRK-LRLLRSLDLSGNRL 442
Score = 58.4 bits (135), Expect = 6e-08
Identities = 86/357 (24%), Positives = 140/357 (39%), Gaps = 24/357 (6%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDHNHIEQ 145
L + N+ + I L L LNL +N LTS + F L NL L+L +N +
Sbjct: 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 160
Query: 146 MSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
R L +L ++ A N ++ + F L + L +N L D L +F
Sbjct: 161 AP----RFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGS 216
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
++ + LR + HL P L +L L N + + F L L++L L N
Sbjct: 217 SNVEVLILSSNFLRHVPK---HLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNY 273
Query: 263 LS-VIVDN-MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L+ +DN F + L L LS N + N I
Sbjct: 274 LTDEGLDNETFWKLSSLEYLDLSSNN---LSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 330
Query: 321 PVVDSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALD 379
P + SL+ + N L I + Q L +H V L N +L+ +P L+ L
Sbjct: 331 P-IRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH 389
Query: 380 LSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT--LSEQDLQRLEAIAEVNLMKNNWH 434
+ R F + T FL+ L++S+N++ + + ++L + ++L N H
Sbjct: 390 NQITGIGREDF---ATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLH 443
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 79.8 bits (188), Expect = 2e-14
Identities = 91/334 (27%), Positives = 151/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ L HL+ N
Sbjct: 311 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL---HLEKN 367
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 368 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 427
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 428 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 484
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L + G R +HVL + RN ++ N++ L
Sbjct: 485 LSGNRLHTLPP---GLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALG 541
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 542 PRAWVDLAHLQLLDIAGNQL--TEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 596
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 597 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 18/261 (6%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
NLR +++ N+ + G F G N+ VL L+ N L V L +LHL +N
Sbjct: 240 NLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNN 296
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+E++ F L+SL+ L L NN ++ L + F L+ L LDLS N L+ + +
Sbjct: 297 KLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP 356
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLK 257
+ + L + + +R ++ + + LE L L N + + F LKRL +
Sbjct: 357 RSLVLLHL---EKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVH 413
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFH 315
L N L + G R + L + N+ ++S+N+I + H
Sbjct: 414 LYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 470
Query: 316 LQTFAPVVDSLKTINFSGNNL 336
F + L++++ SGN L
Sbjct: 471 RDAFRK-LRLLRSLDLSGNRL 490
Score = 58.4 bits (135), Expect = 6e-08
Identities = 86/357 (24%), Positives = 140/357 (39%), Gaps = 24/357 (6%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDHNHIEQ 145
L + N+ + I L L LNL +N LTS + F L NL L+L +N +
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 146 MSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
R L +L ++ A N ++ + F L + L +N L D L +F
Sbjct: 209 AP----RFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGS 264
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
++ + LR + HL P L +L L N + + F L L++L L N
Sbjct: 265 SNVEVLILSSNFLRHVPK---HLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNY 321
Query: 263 LS-VIVDN-MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L+ +DN F + L L LS N + N I
Sbjct: 322 LTDEGLDNETFWKLSSLEYLDLSSNN---LSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 378
Query: 321 PVVDSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALD 379
P + SL+ + N L I + Q L +H V L N +L+ +P L+ L
Sbjct: 379 P-IRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH 437
Query: 380 LSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT--LSEQDLQRLEAIAEVNLMKNNWH 434
+ R F + T FL+ L++S+N++ + + ++L + ++L N H
Sbjct: 438 NQITGIGREDF---ATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLH 491
>BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein.
Length = 402
Score = 79.8 bits (188), Expect = 2e-14
Identities = 91/334 (27%), Positives = 151/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ LHL+ N
Sbjct: 52 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLV---LLHLEKN 108
Query: 142 HIEQMSSETFRHLTSLKTLILANNQI--STLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 109 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 168
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF--KYLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 169 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 225
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L + G R +HVL + RN ++ N++ L
Sbjct: 226 LSGNRLHTLPP---GLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALG 282
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 283 PRAWVDLAHLQLLDIAGNQ--LTEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 337
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 338 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 371
Score = 54.4 bits (125), Expect = 1e-06
Identities = 62/240 (25%), Positives = 104/240 (43%), Gaps = 16/240 (6%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F G N+ VL L+ N L V L +LHL +N +E++ F L+SL+ L L
Sbjct: 2 FNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNNKLEKIPPGAFSELSSLRELYL 58
Query: 163 ANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINT 220
NN ++ L + F L+ L LDLS N L+ + + + + L + + +R ++
Sbjct: 59 QNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHL---EKNAIRSVDA 115
Query: 221 QIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+ + LE L L N + + F LKRL + L N L + G R +
Sbjct: 116 NVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPS---GLPRRVR 172
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFHLQTFAPVVDSLKTINFSGNNL 336
L + N+ ++S+N+I + H F + L++++ SGN L
Sbjct: 173 TLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRK-LRLLRSLDLSGNRL 231
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 79.8 bits (188), Expect = 2e-14
Identities = 91/334 (27%), Positives = 151/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ L HL+ N
Sbjct: 292 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL---HLEKN 348
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 349 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 408
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 409 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 465
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L + G R +HVL + RN ++ N++ L
Sbjct: 466 LSGNRLHTLPP---GLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALG 522
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 523 PRAWVDLAHLQLLDIAGNQL--TEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 577
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 578 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 611
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 18/261 (6%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
NLR +++ N+ + G F G N+ VL L+ N L V L +LHL +N
Sbjct: 221 NLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNN 277
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+E++ F L+SL+ L L NN ++ L + F L+ L LDLS N L+ + +
Sbjct: 278 KLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP 337
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLK 257
+ + L + + +R ++ + + LE L L N + + F LKRL +
Sbjct: 338 RSLVLLHL---EKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVH 394
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFH 315
L N L + G R + L + N+ ++S+N+I + H
Sbjct: 395 LYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 451
Query: 316 LQTFAPVVDSLKTINFSGNNL 336
F + L++++ SGN L
Sbjct: 452 RDAFRK-LRLLRSLDLSGNRL 471
Score = 58.4 bits (135), Expect = 6e-08
Identities = 86/357 (24%), Positives = 140/357 (39%), Gaps = 24/357 (6%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDHNHIEQ 145
L + N+ + I L L LNL +N LTS + F L NL L+L +N +
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 146 MSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
R L +L ++ A N ++ + F L + L +N L D L +F
Sbjct: 190 AP----RFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGS 245
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
++ + LR + HL P L +L L N + + F L L++L L N
Sbjct: 246 SNVEVLILSSNFLRHVPK---HLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNY 302
Query: 263 LS-VIVDN-MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L+ +DN F + L L LS N + N I
Sbjct: 303 LTDEGLDNETFWKLSSLEYLDLSSNN---LSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 359
Query: 321 PVVDSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALD 379
P + SL+ + N L I + Q L +H V L N +L+ +P L+ L
Sbjct: 360 P-IRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH 418
Query: 380 LSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT--LSEQDLQRLEAIAEVNLMKNNWH 434
+ R F + T FL+ L++S+N++ + + ++L + ++L N H
Sbjct: 419 NQITGIGREDF---ATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLH 472
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 79.4 bits (187), Expect = 3e-14
Identities = 91/334 (27%), Positives = 151/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ L HL+ N
Sbjct: 292 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL---HLEKN 348
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 349 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 408
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 409 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 465
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L + G R +HVL + RN ++ N++ L
Sbjct: 466 LSGNRLHTLPP---GLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALG 522
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 523 PRAWVDLAHLQLLDIAGNQL--TEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 577
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 578 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 611
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 18/261 (6%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
NLR +++ N+ + G F G N+ VL L+ N L V L +LHL +N
Sbjct: 221 NLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNN 277
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+E++ F L+SL+ L L NN ++ L + F L+ L LDLS N L+ + +
Sbjct: 278 KLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP 337
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLK 257
+ + L + + +R ++ + + LE L L N + + F LKRL +
Sbjct: 338 RSLVLLHL---EKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVH 394
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFH 315
L N L + G R + L + N+ ++S+N+I + H
Sbjct: 395 LYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 451
Query: 316 LQTFAPVVDSLKTINFSGNNL 336
F + L++++ SGN L
Sbjct: 452 RDAFRK-LRLLRSLDLSGNRL 471
Score = 58.4 bits (135), Expect = 6e-08
Identities = 86/357 (24%), Positives = 140/357 (39%), Gaps = 24/357 (6%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDHNHIEQ 145
L + N+ + I L L LNL +N LTS + F L NL L+L +N +
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 146 MSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
R L +L ++ A N ++ + F L + L +N L D L +F
Sbjct: 190 AP----RFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGS 245
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
++ + LR + HL P L +L L N + + F L L++L L N
Sbjct: 246 SNVEVLILSSNFLRHVPK---HLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNY 302
Query: 263 LS-VIVDN-MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L+ +DN F + L L LS N + N I
Sbjct: 303 LTDEGLDNETFWKLSSLEYLDLSSNN---LSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 359
Query: 321 PVVDSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALD 379
P + SL+ + N L I + Q L +H V L N +L+ +P L+ L
Sbjct: 360 P-IRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH 418
Query: 380 LSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT--LSEQDLQRLEAIAEVNLMKNNWH 434
+ R F + T FL+ L++S+N++ + + ++L + ++L N H
Sbjct: 419 NQITGIGREDF---ATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLH 472
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 79.4 bits (187), Expect = 3e-14
Identities = 91/334 (27%), Positives = 151/334 (45%), Gaps = 24/334 (7%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+LREL++ N+ + G +FW L +L L+L+ NNL+ V A R L+ L HL+ N
Sbjct: 311 SLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLL---HLEKN 367
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
I + + + SL+ L+L +NQ+ + F+ L +L + L +N L + +
Sbjct: 368 AIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP 427
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFK--YLTSDEFISLKRLKKLK 257
+ ++ L I + + I + + LEEL+L N + D F L+ L+ L
Sbjct: 428 RRVRTLMILHNQ---ITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLD 484
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
L GN+L + G R +HVL + RN ++ N++ L
Sbjct: 485 LSGNRLHTLPP---GLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALG 541
Query: 318 TFAPV-VDSLKTINFSGNNLPLNEIAIVLQILPE-IHGVGLANLSLQEIPQNFFTYNEHL 375
A V + L+ ++ +GN L EI + LPE + + L N + +P N F +L
Sbjct: 542 PRAWVDLAHLQLLDIAGNQL--TEIP---EGLPESLEYLYLQNNKISAVPANAFDSTPNL 596
Query: 376 VALDLSWNKLS--RFPFKLLSKTKFLQRLDISHN 407
+ L +NKL+ + K LQ LDI N
Sbjct: 597 KGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630
Score = 59.3 bits (137), Expect = 4e-08
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 18/261 (6%)
Query: 84 NLRELHIVNSNVPSIG--QFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
NLR +++ N+ + G F G N+ VL L+ N L V L +LHL +N
Sbjct: 240 NLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALY---KLHLKNN 296
Query: 142 HIEQMSSETFRHLTSLKTLILANNQIST--LVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+E++ F L+SL+ L L NN ++ L + F L+ L LDLS N L+ + +
Sbjct: 297 KLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP 356
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY--LTSDEFISLKRLKKLK 257
+ + L + + +R ++ + + LE L L N + + F LKRL +
Sbjct: 357 RSLVLLHL---EKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVH 413
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI--DRFH 315
L N L + G R + L + N+ ++S+N+I + H
Sbjct: 414 LYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 470
Query: 316 LQTFAPVVDSLKTINFSGNNL 336
F + L++++ SGN L
Sbjct: 471 RDAFRK-LRLLRSLDLSGNRL 490
Score = 58.4 bits (135), Expect = 6e-08
Identities = 86/357 (24%), Positives = 140/357 (39%), Gaps = 24/357 (6%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDHNHIEQ 145
L + N+ + I L L LNL +N LTS + F L NL L+L +N +
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 146 MSSETFRHL-TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVFKDI 202
R L +L ++ A N ++ + F L + L +N L D L +F
Sbjct: 209 AP----RFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGS 264
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
++ + LR + HL P L +L L N + + F L L++L L N
Sbjct: 265 SNVEVLILSSNFLRHVPK---HLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNY 321
Query: 263 LS-VIVDN-MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L+ +DN F + L L LS N + N I
Sbjct: 322 LTDEGLDNETFWKLSSLEYLDLSSNN---LSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 378
Query: 321 PVVDSLKTINFSGNNLPLNEI-AIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALD 379
P + SL+ + N L I + Q L +H V L N +L+ +P L+ L
Sbjct: 379 P-IRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH 437
Query: 380 LSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT--LSEQDLQRLEAIAEVNLMKNNWH 434
+ R F + T FL+ L++S+N++ + + ++L + ++L N H
Sbjct: 438 NQITGIGREDF---ATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLH 491
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 77.4 bits (182), Expect = 1e-13
Identities = 56/194 (28%), Positives = 87/194 (44%)
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
NLT + A+ +G L ELHL N +E +S E R + L+ L L N ++ L S LF+
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQA 138
Query: 178 LAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
A L L L +N L L ++ L LR++ + L LDLGEN
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 238 LFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXX 297
+ L D +L++L L+GN+L V+ ++ +L L L+ N+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 298 XXXXXXXDISHNKI 311
D+S+N +
Sbjct: 259 LRQLDMLDLSNNSL 272
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/181 (29%), Positives = 80/181 (44%)
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
G L+ L+L+ N L S+ + R + L L L N + + S F+ +L TL+L
Sbjct: 90 GASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKE 149
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
NQ+ L L L LDLS N L L P + + LR L + +
Sbjct: 150 NQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLR 209
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+LE L L N + L D + L+ L L+GN+L+ + F R+L +L LS
Sbjct: 210 GPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSN 269
Query: 285 N 285
N
Sbjct: 270 N 270
Score = 65.7 bits (153), Expect = 4e-10
Identities = 49/187 (26%), Positives = 82/187 (43%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ELH+ ++ + S+ + LRVL+LT N LT + + F+ L L L N +E
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLE 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ L +L L L+ N++ L L L LDL +N L L P++ +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L+ + + P L L L N + + F L++L L L N L+
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 265 VIVDNMF 271
+ + ++
Sbjct: 274 SVPEGLW 280
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 2/167 (1%)
Query: 71 TIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
++ P F +P P LR L + + + + F L L L N L + GL
Sbjct: 106 SLSPEFLRPVP--QLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGL 163
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L N + ++ + T L+TL L NQ+ TL L R +L L L N
Sbjct: 164 KALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L L ++ LR L R+ + + +L+ LDL N
Sbjct: 224 LQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Score = 44.8 bits (101), Expect = 8e-04
Identities = 35/151 (23%), Positives = 65/151 (43%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L ++ ++ + + + + L+ L L++N + +L R + +L +LDL+ N LT L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+F+ L + L + H + L LDL N + L + L+
Sbjct: 133 SGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L NQL + ++ +L L L N+
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 41.5 bits (93), Expect = 0.008
Identities = 42/187 (22%), Positives = 77/187 (41%), Gaps = 2/187 (1%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L+EL L N + L+ + + +L+ L L N L+ + +F + L L L N+
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQL 152
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQI 347
D+S N++ + A L+T++ N L ++
Sbjct: 153 EVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFT-LLRTLDLGENQLETLPPDLLRGP 211
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L ++ + L LQ + ++ L L L+ NKL+R + L LD+S+N
Sbjct: 212 L-QLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 408 KLQTLSE 414
L ++ E
Sbjct: 271 SLASVPE 277
Score = 35.5 bits (78), Expect = 0.50
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 331 FSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPF 390
F+ +LP N +LQ ++ + L++ L+ + F L LDL+ N L+ P
Sbjct: 78 FNLTHLPAN----LLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPS 133
Query: 391 KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L + N+L+ L L L+A+ ++L N
Sbjct: 134 GLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
Score = 31.9 bits (69), Expect = 6.2
Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 2/181 (1%)
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
+L++L L N L + +L VL L+RN + N++
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQL 152
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTY 371
+ + ++ + +L ++ SGN L ++ + + L L+ +P +
Sbjct: 153 EVLEV-SWLHGLKALGHLDLSGNRLRKLPPGLLANFTL-LRTLDLGENQLETLPPDLLRG 210
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L L L NKL LL L+ L ++ NKL ++ Q L + ++L N
Sbjct: 211 PLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 432 N 432
+
Sbjct: 271 S 271
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 77.4 bits (182), Expect = 1e-13
Identities = 61/202 (30%), Positives = 107/202 (52%), Gaps = 8/202 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL++L++ ++ + + + L+NL+ L L HN LT +++ F L NL +L L +NH+
Sbjct: 129 NLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT-CISEGFEQLSNLEDLDLSNNHL 186
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + +F L+SL L L++N++ +L + + RM +L LD + N L + PE+ ++
Sbjct: 187 TTVPA-SFSSLSSLVRLNLSSNELKSLPAEINRM-KRLKHLDCNSNLLETIPPEL-AGME 243
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + RR LR + + L+EL +GEN + L ++ L + L L N+L
Sbjct: 244 SLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKL 301
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ D + R L L LS N
Sbjct: 302 KSVPDEII-LLRSLERLDLSNN 322
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 7/181 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+NL+ LN++HN L ++ + L NL L+L HN + + SE F L++L+ L L+NN
Sbjct: 127 LENLQKLNVSHNKL-KILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN 184
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
++T V F L+ L L+LS N L L E+ + ++ L+ C LL I ++ +
Sbjct: 185 HLTT-VPASFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPELAGM 242
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
LE L L N ++L EF S LK+L + NQ+ ++ + VL L N
Sbjct: 243 -ESLELLYLRRNKLRFL--PEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDN 299
Query: 286 R 286
+
Sbjct: 300 K 300
Score = 70.9 bits (166), Expect = 1e-11
Identities = 88/351 (25%), Positives = 152/351 (43%), Gaps = 19/351 (5%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L + N+++ ++ SF L +L LNL+ N L S+ A+ R + L L + N +
Sbjct: 175 NLEDLDLSNNHLTTVPA-SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLL 232
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + E + SL+ L L N++ L F + L L + +N + L E K +
Sbjct: 233 ETIPPE-LAGMESLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + R L+ + +I L+ LE LDL N L + LK L L+GN L
Sbjct: 290 SILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSLPYS--LGNLHLKFLALEGNPL 346
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
I + + + VL R++ S ++++ H +
Sbjct: 347 RTIRREIISKGTQ-EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVN-IH------AI 398
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEI-HGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
+LK +++S L + + I + + L EIP+ E + +DLS+
Sbjct: 399 ITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSF 458
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
NKLS +L K L LD+ +N L +L E +++ L + +NL N +
Sbjct: 459 NKLSFISLELCVLQK-LTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRF 507
Score = 65.7 bits (153), Expect = 4e-10
Identities = 78/301 (25%), Positives = 136/301 (45%), Gaps = 14/301 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
LNL+ NL+ V +R IN+ + ++ ++E + T L LI++NN++ +L
Sbjct: 41 LNLSGRNLSEVPQCVWR--INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLT 98
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
L R+L L++LD+ DN LT L P +++++L+ L+ + +I +L L+
Sbjct: 99 DDL-RLLPALTVLDIHDNQLTSL-PSAIRELENLQKLNVSHNKLKILPEEITNL-RNLKC 155
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L N + S+ F L L+ L L N L+ V F L L LS N
Sbjct: 156 LYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTT-VPASFSSLSSLVRLNLSSNE-LKSL 212
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D + N ++ + ++SL+ + N L +L E+
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAG--MESLELLYLRRNKLRFLPEFPSCSLLKEL 270
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H VG + + E + ++ LDL NKL P +++ + L+RLD+S+N + +
Sbjct: 271 H-VGENQIEMLE--AEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISS 326
Query: 412 L 412
L
Sbjct: 327 L 327
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
LQ L L+L +N L S+ + L+ L ++L N + + +R T L+T++++NN
Sbjct: 471 LQKLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYRIFT-LETILISNN 528
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
Q+ ++ + +M+ L+ LDL +N L + PE+
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL 561
Score = 52.4 bits (120), Expect = 4e-06
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 79 PAPFVNLREL-HI-VNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
PA ++ L H+ NSN+ G+++L +L L N L + F L EL
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFL--PEFPSCSLLKEL 270
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
H+ N IE + +E +HL S+ L L +N++ ++ + +L L LDLS+N ++ L P
Sbjct: 271 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSL-P 328
Query: 197 EVFKDIQHLRIFKCRRCLLRRINTQI 222
++ HL+ LR I +I
Sbjct: 329 YSLGNL-HLKFLALEGNPLRTIRREI 353
Score = 33.9 bits (74), Expect = 1.5
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L LD+ N+L+ P + + + LQ+L++SHNKL+ L E ++ L + + L N
Sbjct: 107 LTVLDIHDNQLTSLP-SAIRELENLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT 164
Query: 435 C 435
C
Sbjct: 165 C 165
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 77.4 bits (182), Expect = 1e-13
Identities = 61/202 (30%), Positives = 107/202 (52%), Gaps = 8/202 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL++L++ ++ + + + L+NL+ L L HN LT +++ F L NL +L L +NH+
Sbjct: 108 NLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT-CISEGFEQLSNLEDLDLSNNHL 165
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + +F L+SL L L++N++ +L + + RM +L LD + N L + PE+ ++
Sbjct: 166 TTVPA-SFSSLSSLVRLNLSSNELKSLPAEINRM-KRLKHLDCNSNLLETIPPEL-AGME 222
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + RR LR + + L+EL +GEN + L ++ L + L L N+L
Sbjct: 223 SLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKL 280
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ D + R L L LS N
Sbjct: 281 KSVPDEII-LLRSLERLDLSNN 301
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 7/181 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+NL+ LN++HN L ++ + L NL L+L HN + + SE F L++L+ L L+NN
Sbjct: 106 LENLQKLNVSHNKL-KILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN 163
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
++T V F L+ L L+LS N L L E+ + ++ L+ C LL I ++ +
Sbjct: 164 HLTT-VPASFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPELAGM 221
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
LE L L N ++L EF S LK+L + NQ+ ++ + VL L N
Sbjct: 222 -ESLELLYLRRNKLRFL--PEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDN 278
Query: 286 R 286
+
Sbjct: 279 K 279
Score = 70.9 bits (166), Expect = 1e-11
Identities = 88/351 (25%), Positives = 152/351 (43%), Gaps = 19/351 (5%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L + N+++ ++ SF L +L LNL+ N L S+ A+ R + L L + N +
Sbjct: 154 NLEDLDLSNNHLTTVPA-SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLL 211
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + E + SL+ L L N++ L F + L L + +N + L E K +
Sbjct: 212 ETIPPE-LAGMESLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLN 268
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + R L+ + +I L+ LE LDL N L + LK L L+GN L
Sbjct: 269 SILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSLPYS--LGNLHLKFLALEGNPL 325
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
I + + + VL R++ S ++++ H +
Sbjct: 326 RTIRREIISKGTQ-EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVN-IH------AI 377
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEI-HGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
+LK +++S L + + I + + L EIP+ E + +DLS+
Sbjct: 378 ITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSF 437
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
NKLS +L K L LD+ +N L +L E +++ L + +NL N +
Sbjct: 438 NKLSFISLELCVLQK-LTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRF 486
Score = 65.7 bits (153), Expect = 4e-10
Identities = 78/301 (25%), Positives = 136/301 (45%), Gaps = 14/301 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
LNL+ NL+ V +R IN+ + ++ ++E + T L LI++NN++ +L
Sbjct: 20 LNLSGRNLSEVPQCVWR--INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLT 77
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
L R+L L++LD+ DN LT L P +++++L+ L+ + +I +L L+
Sbjct: 78 DDL-RLLPALTVLDIHDNQLTSL-PSAIRELENLQKLNVSHNKLKILPEEITNL-RNLKC 134
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L N + S+ F L L+ L L N L+ V F L L LS N
Sbjct: 135 LYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTT-VPASFSSLSSLVRLNLSSNE-LKSL 191
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D + N ++ + ++SL+ + N L +L E+
Sbjct: 192 PAEINRMKRLKHLDCNSNLLETIPPELAG--MESLELLYLRRNKLRFLPEFPSCSLLKEL 249
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H VG + + E + ++ LDL NKL P +++ + L+RLD+S+N + +
Sbjct: 250 H-VGENQIEMLE--AEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISS 305
Query: 412 L 412
L
Sbjct: 306 L 306
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
LQ L L+L +N L S+ + L+ L ++L N + + +R T L+T++++NN
Sbjct: 450 LQKLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYRIFT-LETILISNN 507
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
Q+ ++ + +M+ L+ LDL +N L + PE+
Sbjct: 508 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL 540
Score = 52.4 bits (120), Expect = 4e-06
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 79 PAPFVNLREL-HI-VNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
PA ++ L H+ NSN+ G+++L +L L N L + F L EL
Sbjct: 192 PAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFL--PEFPSCSLLKEL 249
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
H+ N IE + +E +HL S+ L L +N++ ++ + +L L LDLS+N ++ L P
Sbjct: 250 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSL-P 307
Query: 197 EVFKDIQHLRIFKCRRCLLRRINTQI 222
++ HL+ LR I +I
Sbjct: 308 YSLGNL-HLKFLALEGNPLRTIRREI 332
Score = 33.9 bits (74), Expect = 1.5
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L LD+ N+L+ P + + + LQ+L++SHNKL+ L E ++ L + + L N
Sbjct: 86 LTVLDIHDNQLTSLP-SAIRELENLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT 143
Query: 435 C 435
C
Sbjct: 144 C 144
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 77.4 bits (182), Expect = 1e-13
Identities = 61/202 (30%), Positives = 107/202 (52%), Gaps = 8/202 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL++L++ ++ + + + L+NL+ L L HN LT +++ F L NL +L L +NH+
Sbjct: 129 NLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT-CISEGFEQLSNLEDLDLSNNHL 186
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + +F L+SL L L++N++ +L + + RM +L LD + N L + PE+ ++
Sbjct: 187 TTVPA-SFSSLSSLVRLNLSSNELKSLPAEINRM-KRLKHLDCNSNLLETIPPEL-AGME 243
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + RR LR + + L+EL +GEN + L ++ L + L L N+L
Sbjct: 244 SLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKL 301
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ D + R L L LS N
Sbjct: 302 KSVPDEII-LLRSLERLDLSNN 322
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 7/181 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+NL+ LN++HN L ++ + L NL L+L HN + + SE F L++L+ L L+NN
Sbjct: 127 LENLQKLNVSHNKL-KILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN 184
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
++T V F L+ L L+LS N L L E+ + ++ L+ C LL I ++ +
Sbjct: 185 HLTT-VPASFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPELAGM 242
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
LE L L N ++L EF S LK+L + NQ+ ++ + VL L N
Sbjct: 243 -ESLELLYLRRNKLRFL--PEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDN 299
Query: 286 R 286
+
Sbjct: 300 K 300
Score = 70.9 bits (166), Expect = 1e-11
Identities = 88/351 (25%), Positives = 152/351 (43%), Gaps = 19/351 (5%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L + N+++ ++ SF L +L LNL+ N L S+ A+ R + L L + N +
Sbjct: 175 NLEDLDLSNNHLTTVPA-SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLL 232
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + E + SL+ L L N++ L F + L L + +N + L E K +
Sbjct: 233 ETIPPE-LAGMESLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + R L+ + +I L+ LE LDL N L + LK L L+GN L
Sbjct: 290 SILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSLPYS--LGNLHLKFLALEGNPL 346
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
I + + + VL R++ S ++++ H +
Sbjct: 347 RTIRREIISKGTQ-EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVN-IH------AI 398
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEI-HGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
+LK +++S L + + I + + L EIP+ E + +DLS+
Sbjct: 399 ITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSF 458
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
NKLS +L K L LD+ +N L +L E +++ L + +NL N +
Sbjct: 459 NKLSFISLELCVLQK-LTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRF 507
Score = 65.7 bits (153), Expect = 4e-10
Identities = 78/301 (25%), Positives = 136/301 (45%), Gaps = 14/301 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
LNL+ NL+ V +R IN+ + ++ ++E + T L LI++NN++ +L
Sbjct: 41 LNLSGRNLSEVPQCVWR--INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLT 98
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
L R+L L++LD+ DN LT L P +++++L+ L+ + +I +L L+
Sbjct: 99 DDL-RLLPALTVLDIHDNQLTSL-PSAIRELENLQKLNVSHNKLKILPEEITNL-RNLKC 155
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L N + S+ F L L+ L L N L+ V F L L LS N
Sbjct: 156 LYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTT-VPASFSSLSSLVRLNLSSNE-LKSL 212
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D + N ++ + ++SL+ + N L +L E+
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAG--MESLELLYLRRNKLRFLPEFPSCSLLKEL 270
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H VG + + E + ++ LDL NKL P +++ + L+RLD+S+N + +
Sbjct: 271 H-VGENQIEMLE--AEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISS 326
Query: 412 L 412
L
Sbjct: 327 L 327
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
LQ L L+L +N L S+ + L+ L ++L N + + +R T L+T++++NN
Sbjct: 471 LQKLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYRIFT-LETILISNN 528
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
Q+ ++ + +M+ L+ LDL +N L + PE+
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL 561
Score = 52.4 bits (120), Expect = 4e-06
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 79 PAPFVNLREL-HI-VNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
PA ++ L H+ NSN+ G+++L +L L N L + F L EL
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFL--PEFPSCSLLKEL 270
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
H+ N IE + +E +HL S+ L L +N++ ++ + +L L LDLS+N ++ L P
Sbjct: 271 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSL-P 328
Query: 197 EVFKDIQHLRIFKCRRCLLRRINTQI 222
++ HL+ LR I +I
Sbjct: 329 YSLGNL-HLKFLALEGNPLRTIRREI 353
Score = 33.9 bits (74), Expect = 1.5
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L LD+ N+L+ P + + + LQ+L++SHNKL+ L E ++ L + + L N
Sbjct: 107 LTVLDIHDNQLTSLP-SAIRELENLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT 164
Query: 435 C 435
C
Sbjct: 165 C 165
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 77.4 bits (182), Expect = 1e-13
Identities = 61/202 (30%), Positives = 107/202 (52%), Gaps = 8/202 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL++L++ ++ + + + L+NL+ L L HN LT +++ F L NL +L L +NH+
Sbjct: 129 NLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT-CISEGFEQLSNLEDLDLSNNHL 186
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + +F L+SL L L++N++ +L + + RM +L LD + N L + PE+ ++
Sbjct: 187 TTVPA-SFSSLSSLVRLNLSSNELKSLPAEINRM-KRLKHLDCNSNLLETIPPEL-AGME 243
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
L + RR LR + + L+EL +GEN + L ++ L + L L N+L
Sbjct: 244 SLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKL 301
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ D + R L L LS N
Sbjct: 302 KSVPDEII-LLRSLERLDLSNN 322
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 7/181 (3%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L+NL+ LN++HN L ++ + L NL L+L HN + + SE F L++L+ L L+NN
Sbjct: 127 LENLQKLNVSHNKL-KILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN 184
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
++T V F L+ L L+LS N L L E+ + ++ L+ C LL I ++ +
Sbjct: 185 HLTT-VPASFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPELAGM 242
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
LE L L N ++L EF S LK+L + NQ+ ++ + VL L N
Sbjct: 243 -ESLELLYLRRNKLRFL--PEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDN 299
Query: 286 R 286
+
Sbjct: 300 K 300
Score = 70.9 bits (166), Expect = 1e-11
Identities = 88/351 (25%), Positives = 152/351 (43%), Gaps = 19/351 (5%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L + N+++ ++ SF L +L LNL+ N L S+ A+ R + L L + N +
Sbjct: 175 NLEDLDLSNNHLTTVPA-SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLL 232
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
E + E + SL+ L L N++ L F + L L + +N + L E K +
Sbjct: 233 ETIPPE-LAGMESLELLYLRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + R L+ + +I L+ LE LDL N L + LK L L+GN L
Sbjct: 290 SILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSLPYS--LGNLHLKFLALEGNPL 346
Query: 264 SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVV 323
I + + + VL R++ S ++++ H +
Sbjct: 347 RTIRREIISKGTQ-EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVN-IH------AI 398
Query: 324 DSLKTINFSGNNLPLNEIAIVLQILPEI-HGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
+LK +++S L + + I + + L EIP+ E + +DLS+
Sbjct: 399 ITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSF 458
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
NKLS +L K L LD+ +N L +L E +++ L + +NL N +
Sbjct: 459 NKLSFISLELCVLQK-LTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRF 507
Score = 65.7 bits (153), Expect = 4e-10
Identities = 78/301 (25%), Positives = 136/301 (45%), Gaps = 14/301 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
LNL+ NL+ V +R IN+ + ++ ++E + T L LI++NN++ +L
Sbjct: 41 LNLSGRNLSEVPQCVWR--INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLT 98
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
L R+L L++LD+ DN LT L P +++++L+ L+ + +I +L L+
Sbjct: 99 DDL-RLLPALTVLDIHDNQLTSL-PSAIRELENLQKLNVSHNKLKILPEEITNL-RNLKC 155
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L L N + S+ F L L+ L L N L+ V F L L LS N
Sbjct: 156 LYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTT-VPASFSSLSSLVRLNLSSNE-LKSL 212
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
D + N ++ + ++SL+ + N L +L E+
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAG--MESLELLYLRRNKLRFLPEFPSCSLLKEL 270
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQT 411
H VG + + E + ++ LDL NKL P +++ + L+RLD+S+N + +
Sbjct: 271 H-VGENQIEMLE--AEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISS 326
Query: 412 L 412
L
Sbjct: 327 L 327
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
LQ L L+L +N L S+ + L+ L ++L N + + +R T L+T++++NN
Sbjct: 471 LQKLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYRIFT-LETILISNN 528
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
Q+ ++ + +M+ L+ LDL +N L + PE+
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL 561
Score = 52.4 bits (120), Expect = 4e-06
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 79 PAPFVNLREL-HI-VNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
PA ++ L H+ NSN+ G+++L +L L N L + F L EL
Sbjct: 213 PAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFL--PEFPSCSLLKEL 270
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
H+ N IE + +E +HL S+ L L +N++ ++ + +L L LDLS+N ++ L P
Sbjct: 271 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII-LLRSLERLDLSNNDISSL-P 328
Query: 197 EVFKDIQHLRIFKCRRCLLRRINTQI 222
++ HL+ LR I +I
Sbjct: 329 YSLGNL-HLKFLALEGNPLRTIRREI 353
Score = 33.9 bits (74), Expect = 1.5
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L LD+ N+L+ P + + + LQ+L++SHNKL+ L E ++ L + + L N
Sbjct: 107 LTVLDIHDNQLTSLP-SAIRELENLQKLNVSHNKLKILPE-EITNLRNLKCLYLQHNELT 164
Query: 435 C 435
C
Sbjct: 165 C 165
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 77.4 bits (182), Expect = 1e-13
Identities = 56/194 (28%), Positives = 87/194 (44%)
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
NLT + A+ +G L ELHL N +E +S E R + L+ L L N ++ L S LF+
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQA 138
Query: 178 LAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
A L L L +N L L ++ L LR++ + L LDLGEN
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 238 LFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXX 297
+ L D +L++L L+GN+L V+ ++ +L L L+ N+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 298 XXXXXXXDISHNKI 311
D+S+N +
Sbjct: 259 LRQLDMLDLSNNSL 272
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/181 (29%), Positives = 80/181 (44%)
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
G L+ L+L+ N L S+ + R + L L L N + + S F+ +L TL+L
Sbjct: 90 GASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKE 149
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
NQ+ L L L LDLS N L L P + + LR L + +
Sbjct: 150 NQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLR 209
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+LE L L N + L D + L+ L L+GN+L+ + F R+L +L LS
Sbjct: 210 GPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSN 269
Query: 285 N 285
N
Sbjct: 270 N 270
Score = 65.7 bits (153), Expect = 4e-10
Identities = 49/187 (26%), Positives = 82/187 (43%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ELH+ ++ + S+ + LRVL+LT N LT + + F+ L L L N +E
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLE 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ L +L L L+ N++ L L L LDL +N L L P++ +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L+ + + P L L L N + + F L++L L L N L+
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 265 VIVDNMF 271
+ + ++
Sbjct: 274 SVPEGLW 280
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 2/167 (1%)
Query: 71 TIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
++ P F +P P LR L + + + + F L L L N L + GL
Sbjct: 106 SLSPEFLRPVP--QLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGL 163
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L N + ++ + T L+TL L NQ+ TL L R +L L L N
Sbjct: 164 KALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L L ++ LR L R+ + + +L+ LDL N
Sbjct: 224 LQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Score = 44.8 bits (101), Expect = 8e-04
Identities = 35/151 (23%), Positives = 65/151 (43%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L ++ ++ + + + + L+ L L++N + +L R + +L +LDL+ N LT L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+F+ L + L + H + L LDL N + L + L+
Sbjct: 133 SGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L NQL + ++ +L L L N+
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 41.5 bits (93), Expect = 0.008
Identities = 42/187 (22%), Positives = 77/187 (41%), Gaps = 2/187 (1%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L+EL L N + L+ + + +L+ L L N L+ + +F + L L L N+
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQL 152
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQI 347
D+S N++ + A L+T++ N L ++
Sbjct: 153 EVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFT-LLRTLDLGENQLETLPPDLLRGP 211
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L ++ + L LQ + ++ L L L+ NKL+R + L LD+S+N
Sbjct: 212 L-QLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 408 KLQTLSE 414
L ++ E
Sbjct: 271 SLASVPE 277
Score = 35.5 bits (78), Expect = 0.50
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 331 FSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPF 390
F+ +LP N +LQ ++ + L++ L+ + F L LDL+ N L+ P
Sbjct: 78 FNLTHLPAN----LLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPS 133
Query: 391 KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L + N+L+ L L L+A+ ++L N
Sbjct: 134 GLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
Score = 31.9 bits (69), Expect = 6.2
Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 2/181 (1%)
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKI 311
+L++L L N L + +L VL L+RN + N++
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQL 152
Query: 312 DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTY 371
+ + ++ + +L ++ SGN L ++ + + L L+ +P +
Sbjct: 153 EVLEV-SWLHGLKALGHLDLSGNRLRKLPPGLLANFTL-LRTLDLGENQLETLPPDLLRG 210
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L L L NKL LL L+ L ++ NKL ++ Q L + ++L N
Sbjct: 211 PLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 432 N 432
+
Sbjct: 271 S 271
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 77.0 bits (181), Expect = 2e-13
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 9/307 (2%)
Query: 108 NLRVLNLTHNNLTSV-VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
N ++L L NN+ + + +F +NLT L L N++ +++ + + L ++ L N+
Sbjct: 70 NTQILLLQTNNIAKIEYSTDFP--VNLTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L+ L L ++ N L+ ++P F + +L L+ IN++ + +
Sbjct: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
P LE L +GEN + F L L+ L + G L+ I DN L ++ NR
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIV 344
D++ N I+R F+ ++ LK + NN+P ++ ++
Sbjct: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNML-HLKELGI--NNMPELISIDSLA 304
Query: 345 LQILPEIHGV-GLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
+ LP++ + N L I N F L +L L+ N LS + L+ +
Sbjct: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
Query: 404 ISHNKLQ 410
I N ++
Sbjct: 365 IHSNPIR 371
Score = 61.3 bits (142), Expect = 9e-09
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 2/203 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +N+ S+ + + L + L N LT + L NL EL+++HN
Sbjct: 92 VNLTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S F L +L L L +N++ + S+ F L L IL + +NP+ + FK +
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR L I + LE + +N + + LK L L+ N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
++ I F + LH+ L N
Sbjct: 272 INRIRRGDF--SNMLHLKELGIN 292
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P +NLR L I N+ I + GL+NL ++ N L V + ++NL L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 141 NHIEQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I ++ F ++ LK L + N ++ ++ S L L ++ ++NP L+ ++P
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
F + L L + +P L+E+ + N
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L I + + I +F L NLR L + NLT + + GL NL + N +
Sbjct: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEVFKDI 202
++ + + +LK L L N I+ + F + L L +++ P L ++ ++
Sbjct: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
Query: 203 QHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
LR I L I+ + +P+LE L L N L SL LK++ + N
Sbjct: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Query: 262 QL 263
+
Sbjct: 369 PI 370
Score = 45.6 bits (103), Expect = 5e-04
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L LDL +N +T+ + +L + L+ N+L+ + + L L ++ N
Sbjct: 94 LTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV-LQI 347
++ N++ + + F + +L+ + N P+ I + +
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWF-DALPNLEILMIGEN--PIIRIKDMNFKP 210
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L + + +A ++L EIP N E+L ++ N+L + P L K L+ LD++ N
Sbjct: 211 LINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKN 270
Query: 408 KLQTLSEQDLQRLEAIAEVNL 428
+ + D + + E+ +
Sbjct: 271 PINRIRRGDFSNMLHLKELGI 291
Score = 36.3 bits (80), Expect = 0.29
Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 8/76 (10%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
+ N++++++PQ L+++ L NKL+ P K LS+ LQ L I+HN L T+S
Sbjct: 107 VTNINVKKMPQ--------LLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 416 DLQRLEAIAEVNLMKN 431
L + ++L N
Sbjct: 159 AFIGLHNLLRLHLNSN 174
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 63.7 bits (148), Expect = 2e-09
Identities = 93/395 (23%), Positives = 164/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N + P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFNEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 63.3 bits (147), Expect = 2e-09
Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N ++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 76.6 bits (180), Expect = 2e-13
Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 27/379 (7%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + +N+ +G SF L L L +NN+ + + + GL N+ L+L +
Sbjct: 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
Query: 142 HIEQMSSE---------TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN--P 190
+Q S +F+ L L+ L + +N I + S +F L L L LS++
Sbjct: 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
Query: 191 LTDLNPEVFKDIQH--LRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEF 247
L L E F + H L I + + +I + + + LE LDLG N + + LT E+
Sbjct: 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN--RXXXXXXXXXXXXXXXXXXD 305
L+ + ++ L N+ + N F L L L R + D
Sbjct: 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNL--------PLNEIAIVLQILPEIHGVGLA 357
+S+N I + ++ L+ ++ NNL P I L+ L +H + L
Sbjct: 513 LSNNNIANIN-DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-LKGLSHLHILNLE 570
Query: 358 NLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL 417
+ EIP F L +DL N L+ P + + L+ L++ N + ++ ++
Sbjct: 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
Query: 418 -QRLEAIAEVNLMKNNWHC 435
+ E+++ N + C
Sbjct: 631 GPAFRNLTELDMRFNPFDC 649
Score = 68.5 bits (160), Expect = 6e-11
Identities = 51/160 (31%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ VLNLTHN L + A NF LT L + N I ++ E + L LK L L +N++
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLL--RRINTQIYHL 225
S L + F L+ L L N + + F ++L L ++ TQ+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ-- 169
Query: 226 VPRLEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQL 263
+ L+EL L N + L S+E + LKKL+L NQ+
Sbjct: 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 77 TQPAPFVNLRELHIV---NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN------- 126
+ P+PF LR L I+ N+N+ +I GL+ L +L+L HNNL +
Sbjct: 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
Query: 127 -FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILD 185
+GL +L L+L+ N +++ E F+ L LK + L N ++TL + +F L L+
Sbjct: 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
Query: 186 LSDNPLTDLNPEVF 199
L N +T + +VF
Sbjct: 617 LQKNLITSVEKKVF 630
Score = 63.3 bits (147), Expect = 2e-09
Identities = 93/395 (23%), Positives = 163/395 (41%), Gaps = 34/395 (8%)
Query: 68 NFLTIGPIFTQPAPF----VNLRELHIVNSNVPSIGQFSFWGLQ--NLRVLNLTHNNLTS 121
N + +GP T+ ++R L + NS + + +F GL+ NL +L+L++NNL
Sbjct: 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
Query: 122 VVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN---QISTLVSR----- 173
V D+F L L L++N+I+ + S + L +++ L L + Q +L S
Sbjct: 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
Query: 174 -LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL--LRRINTQIYHLVPR-- 228
F+ L L L++ DN + + +F + +L+ LR + + + +
Sbjct: 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRE-LHVLTLSRNRX 287
L L+L +N + SD F L L+ L L N++ + R E + + LS N+
Sbjct: 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
Query: 288 XXXXXXXXX---XXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP-LNEIAI 343
++ +D F P + +L ++ S NN+ +N+ +
Sbjct: 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQP-LRNLTILDLSNNNIANINDDML 526
Query: 344 ----VLQILPEIHGVGLANLSLQEIPQN---FFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L+IL H LA L P F HL L+L N P ++
Sbjct: 527 EGLEKLEILDLQHN-NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
Query: 397 KFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L+ +D+ N L TL ++ +NL KN
Sbjct: 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
Score = 58.4 bits (135), Expect = 6e-08
Identities = 90/372 (24%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF-----------RH- 153
L L+VLNL HN L+ + F NLTELHL N I+++ + F H
Sbjct: 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
Query: 154 ------------LTSLKTLILANNQISTLVSRLFRMLAKLSI--LDLSDNPLTDLNPEVF 199
L +L+ L+L+NN+I L S + A S+ L+LS N + + +P F
Sbjct: 158 GLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLV---PRLEELDLGENLFKYLTSDEFISLK--RLK 254
I L L T+ L + L L + ++ F+ LK L
Sbjct: 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L L N L+V+ ++ F +L L N ++ + +
Sbjct: 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS 337
Query: 315 HLQTFAPVVDS--------LKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN--LSLQEI 364
P +D L+ +N N++P + + ++ + + L+N SL+ +
Sbjct: 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI-NLKYLSLSNSFTSLRTL 396
Query: 365 PQNFFTYNEH--LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL-QTLSEQDLQRLE 421
F H L L+L+ NK+S+ S L+ LD+ N++ Q L+ Q+ + LE
Sbjct: 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
Query: 422 AIAEVNLMKNNW 433
I E+ L N +
Sbjct: 457 NIFEIYLSYNKY 468
Score = 56.0 bits (129), Expect = 3e-07
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ L++ ++ + + +F L L++ N ++ + + + L L L+L HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL--TDLNPEV-FK 200
Q+S +TF T+L L L +N I + + F L LDLS N L T L +V +
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 201 DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDG 260
++Q L + + L+ I+ L++L+L N K + F ++ RL L L+
Sbjct: 172 NLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
Query: 261 NQL 263
QL
Sbjct: 231 VQL 233
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
V + +H LT V D N+T L+L HN + ++ + F + L +L + N IS L
Sbjct: 34 VADCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
L + L L +L+L N L+ L+ + F +L +++I + L
Sbjct: 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG--RNRELHVLTLSRNR 286
LDL N + L+ L++L L N++ + N L L LS N+
Sbjct: 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP- 337
VL L+ N+ D+ N I + + + LK +N N L
Sbjct: 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPMLKVLNLQHNELSQ 113
Query: 338 LNEIAIVLQI-LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKT 396
L++ L E+H L + S+Q+I N F ++L+ LDLS N LS +
Sbjct: 114 LSDKTFAFCTNLTELH---LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
Query: 397 KFLQRLDISHNKLQTLSEQDL 417
+ LQ L +S+NK+Q L ++L
Sbjct: 171 ENLQELLLSNNKIQALKSEEL 191
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L + L+ +P FT L +LD+ +N +S+ +L K L+ L++ HN+L LS
Sbjct: 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS 115
Query: 414 EQDLQRLEAIAEVNLMKNN 432
++ + E++LM N+
Sbjct: 116 DKTFAFCTNLTELHLMSNS 134
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++HN++ R F L +++ N + E + Q LP + + L + L ++
Sbjct: 57 NLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHNELSQL 114
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
F + +L L L N + + K K L LD+SHN L + +LE +
Sbjct: 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
Query: 425 EVNLMKNN 432
E+ L+ NN
Sbjct: 175 EL-LLSNN 181
Score = 35.1 bits (77), Expect = 0.66
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 357 ANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQD 416
++L L ++P + T ++ L+L+ N+L R P ++ L LD+ N + L +
Sbjct: 38 SHLKLTQVPDDLPT---NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
Query: 417 LQRLEAIAEVNLMKN 431
Q+L + +NL N
Sbjct: 95 CQKLPMLKVLNLQHN 109
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 9/307 (2%)
Query: 108 NLRVLNLTHNNLTSV-VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
N ++L L NN+ + + +F +NLT L L N++ +++ + + L ++ L N+
Sbjct: 70 NTQILLLQTNNIAKIEYSTDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L+ L L ++ N L+ ++P F + +L L+ IN++ + +
Sbjct: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
P LE L +GEN + F L L+ L + G L+ I DN L ++ NR
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIV 344
D++ N I+R F+ ++ LK + NN+P ++ ++
Sbjct: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNML-HLKELGI--NNMPELISIDSLA 304
Query: 345 LQILPEIHGV-GLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
+ LP++ + N L I N F L +L L+ N LS + L+ +
Sbjct: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
Query: 404 ISHNKLQ 410
I N ++
Sbjct: 365 IHSNPIR 371
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 2/203 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +N+ S+ + + L + L N LT + L NL EL+++HN
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S F L +L L L +N++ + S+ F L L IL + +NP+ + FK +
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR L I + LE + +N + + LK L L+ N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
++ I F + LH+ L N
Sbjct: 272 INRIRRGDF--SNMLHLKELGIN 292
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P +NLR L I N+ I + GL+NL ++ N L V + ++NL L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 141 NHIEQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I ++ F ++ LK L + N ++ ++ S L L ++ ++NP L+ ++P
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
F + L L + +P L+E+ + N
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L I + + I +F L NLR L + NLT + + GL NL + N +
Sbjct: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEVFKDI 202
++ + + +LK L L N I+ + F + L L +++ P L ++ ++
Sbjct: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
Query: 203 QHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
LR I L I+ + +P+LE L L N L SL LK++ + N
Sbjct: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Query: 262 QL 263
+
Sbjct: 369 PI 370
Score = 44.8 bits (101), Expect = 8e-04
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L LDL +N +T+ + +L + L+ N+L+ + + L L ++ N
Sbjct: 94 LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV-LQI 347
++ N++ + + F + +L+ + N P+ I + +
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWF-DALPNLEILMIGEN--PIIRIKDMNFKP 210
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L + + +A ++L EIP N E+L ++ N+L + P L K L+ LD++ N
Sbjct: 211 LINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKN 270
Query: 408 KLQTLSEQDLQRLEAIAEVNL 428
+ + D + + E+ +
Sbjct: 271 PINRIRRGDFSNMLHLKELGI 291
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/79 (30%), Positives = 38/79 (48%)
Query: 353 GVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
G+ L+ +L + L+++ L NKL+ P K LS+ LQ L I+HN L T+
Sbjct: 96 GLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTI 155
Query: 413 SEQDLQRLEAIAEVNLMKN 431
S L + ++L N
Sbjct: 156 SPGAFIGLHNLLRLHLNSN 174
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 9/307 (2%)
Query: 108 NLRVLNLTHNNLTSV-VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
N ++L L NN+ + + +F +NLT L L N++ +++ + + L ++ L N+
Sbjct: 70 NTQILLLQTNNIAKIEYSTDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L+ L L ++ N L+ ++P F + +L L+ IN++ + +
Sbjct: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
P LE L +GEN + F L L+ L + G L+ I DN L ++ NR
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIV 344
D++ N I+R F+ ++ LK + NN+P ++ ++
Sbjct: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNML-HLKELGI--NNMPELISIDSLA 304
Query: 345 LQILPEIHGV-GLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
+ LP++ + N L I N F L +L L+ N LS + L+ +
Sbjct: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
Query: 404 ISHNKLQ 410
I N ++
Sbjct: 365 IHSNPIR 371
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 2/203 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +N+ S+ + + L + L N LT + L NL EL+++HN
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S F L +L L L +N++ + S+ F L L IL + +NP+ + FK +
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR L I + LE + +N + + LK L L+ N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
++ I F + LH+ L N
Sbjct: 272 INRIRRGDF--SNMLHLKELGIN 292
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P +NLR L I N+ I + GL+NL ++ N L V + ++NL L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 141 NHIEQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I ++ F ++ LK L + N ++ ++ S L L ++ ++NP L+ ++P
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
F + L L + +P L+E+ + N
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L I + + I +F L NLR L + NLT + + GL NL + N +
Sbjct: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEVFKDI 202
++ + + +LK L L N I+ + F + L L +++ P L ++ ++
Sbjct: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
Query: 203 QHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
LR I L I+ + +P+LE L L N L SL LK++ + N
Sbjct: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Query: 262 QL 263
+
Sbjct: 369 PI 370
Score = 44.8 bits (101), Expect = 8e-04
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L LDL +N +T+ + +L + L+ N+L+ + + L L ++ N
Sbjct: 94 LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV-LQI 347
++ N++ + + F + +L+ + N P+ I + +
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWF-DALPNLEILMIGEN--PIIRIKDMNFKP 210
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L + + +A ++L EIP N E+L ++ N+L + P L K L+ LD++ N
Sbjct: 211 LINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKN 270
Query: 408 KLQTLSEQDLQRLEAIAEVNL 428
+ + D + + E+ +
Sbjct: 271 PINRIRRGDFSNMLHLKELGI 291
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/79 (30%), Positives = 38/79 (48%)
Query: 353 GVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
G+ L+ +L + L+++ L NKL+ P K LS+ LQ L I+HN L T+
Sbjct: 96 GLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTI 155
Query: 413 SEQDLQRLEAIAEVNLMKN 431
S L + ++L N
Sbjct: 156 SPGAFIGLHNLLRLHLNSN 174
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 9/307 (2%)
Query: 108 NLRVLNLTHNNLTSV-VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
N ++L L NN+ + + +F +NLT L L N++ +++ + + L ++ L N+
Sbjct: 70 NTQILLLQTNNIAKIEYSTDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L+ L L ++ N L+ ++P F + +L L+ IN++ + +
Sbjct: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
P LE L +GEN + F L L+ L + G L+ I DN L ++ NR
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIV 344
D++ N I+R F+ ++ LK + NN+P ++ ++
Sbjct: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNML-HLKELGI--NNMPELISIDSLA 304
Query: 345 LQILPEIHGV-GLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
+ LP++ + N L I N F L +L L+ N LS + L+ +
Sbjct: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
Query: 404 ISHNKLQ 410
I N ++
Sbjct: 365 IHSNPIR 371
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 2/203 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +N+ S+ + + L + L N LT + L NL EL+++HN
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S F L +L L L +N++ + S+ F L L IL + +NP+ + FK +
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR L I + LE + +N + + LK L L+ N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
++ I F + LH+ L N
Sbjct: 272 INRIRRGDF--SNMLHLKELGIN 292
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P +NLR L I N+ I + GL+NL ++ N L V + ++NL L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 141 NHIEQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I ++ F ++ LK L + N ++ ++ S L L ++ ++NP L+ ++P
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
F + L L + +P L+E+ + N
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L I + + I +F L NLR L + NLT + + GL NL + N +
Sbjct: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEVFKDI 202
++ + + +LK L L N I+ + F + L L +++ P L ++ ++
Sbjct: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
Query: 203 QHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
LR I L I+ + +P+LE L L N L SL LK++ + N
Sbjct: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Query: 262 QL 263
+
Sbjct: 369 PI 370
Score = 44.8 bits (101), Expect = 8e-04
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L LDL +N +T+ + +L + L+ N+L+ + + L L ++ N
Sbjct: 94 LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV-LQI 347
++ N++ + + F + +L+ + N P+ I + +
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWF-DALPNLEILMIGEN--PIIRIKDMNFKP 210
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L + + +A ++L EIP N E+L ++ N+L + P L K L+ LD++ N
Sbjct: 211 LINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKN 270
Query: 408 KLQTLSEQDLQRLEAIAEVNL 428
+ + D + + E+ +
Sbjct: 271 PINRIRRGDFSNMLHLKELGI 291
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/79 (30%), Positives = 38/79 (48%)
Query: 353 GVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
G+ L+ +L + L+++ L NKL+ P K LS+ LQ L I+HN L T+
Sbjct: 96 GLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTI 155
Query: 413 SEQDLQRLEAIAEVNLMKN 431
S L + ++L N
Sbjct: 156 SPGAFIGLHNLLRLHLNSN 174
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 9/307 (2%)
Query: 108 NLRVLNLTHNNLTSV-VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
N ++L L NN+ + + +F +NLT L L N++ +++ + + L ++ L N+
Sbjct: 70 NTQILLLQTNNIAKIEYSTDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L+ L L ++ N L+ ++P F + +L L+ IN++ + +
Sbjct: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
P LE L +GEN + F L L+ L + G L+ I DN L ++ NR
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLP--LNEIAIV 344
D++ N I+R F+ ++ LK + NN+P ++ ++
Sbjct: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNML-HLKELGI--NNMPELISIDSLA 304
Query: 345 LQILPEIHGV-GLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
+ LP++ + N L I N F L +L L+ N LS + L+ +
Sbjct: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
Query: 404 ISHNKLQ 410
I N ++
Sbjct: 365 IHSNPIR 371
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 2/203 (0%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +N+ S+ + + L + L N LT + L NL EL+++HN
Sbjct: 92 VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S F L +L L L +N++ + S+ F L L IL + +NP+ + FK +
Sbjct: 152 LSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPL 211
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR L I + LE + +N + + LK L L+ N
Sbjct: 212 INLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNP 271
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
++ I F + LH+ L N
Sbjct: 272 INRIRRGDF--SNMLHLKELGIN 292
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P +NLR L I N+ I + GL+NL ++ N L V + ++NL L L+
Sbjct: 210 PLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK 269
Query: 141 NHIEQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I ++ F ++ LK L + N ++ ++ S L L ++ ++NP L+ ++P
Sbjct: 270 NPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
F + L L + +P L+E+ + N
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL L I + + I +F L NLR L + NLT + + GL NL + N +
Sbjct: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEVFKDI 202
++ + + +LK L L N I+ + F + L L +++ P L ++ ++
Sbjct: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
Query: 203 QHLR-IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
LR I L I+ + +P+LE L L N L SL LK++ + N
Sbjct: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
Query: 262 QL 263
+
Sbjct: 369 PI 370
Score = 44.8 bits (101), Expect = 8e-04
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L LDL +N +T+ + +L + L+ N+L+ + + L L ++ N
Sbjct: 94 LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLS 153
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV-LQI 347
++ N++ + + F + +L+ + N P+ I + +
Sbjct: 154 TISPGAFIGLHNLLRLHLNSNRLQMINSKWF-DALPNLEILMIGEN--PIIRIKDMNFKP 210
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L + + +A ++L EIP N E+L ++ N+L + P L K L+ LD++ N
Sbjct: 211 LINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKN 270
Query: 408 KLQTLSEQDLQRLEAIAEVNL 428
+ + D + + E+ +
Sbjct: 271 PINRIRRGDFSNMLHLKELGI 291
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/79 (30%), Positives = 38/79 (48%)
Query: 353 GVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
G+ L+ +L + L+++ L NKL+ P K LS+ LQ L I+HN L T+
Sbjct: 96 GLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTI 155
Query: 413 SEQDLQRLEAIAEVNLMKN 431
S L + ++L N
Sbjct: 156 SPGAFIGLHNLLRLHLNSN 174
>BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 75.8 bits (178), Expect = 4e-13
Identities = 65/222 (29%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + ++ + + SF L L L+L++N+ V NF + +L
Sbjct: 515 SQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 574
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 575 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 633
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 634 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALT 693
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 694 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 735
Score = 66.5 bits (155), Expect = 2e-10
Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 458 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 517
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ L + + +PRLE LDL N + F++ L+ L
Sbjct: 518 LPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 577
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 578 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 636
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 637 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNQLKALTNG 695
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 696 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 755
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 756 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 798
Score = 61.7 bits (143), Expect = 7e-09
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L + F
Sbjct: 271 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAF 330
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 331 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 390
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 391 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 450
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 451 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 509
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 510 QAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYN 555
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 568 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 627 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 687 NQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 746
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 747 PLASALQILDVSAN 760
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/188 (29%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L++N++
Sbjct: 477 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLY 536
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 537 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 596
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 597 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 655
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 656 QVLRLRDN 663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 120 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 179
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL NLT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 180 YKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 235
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 236 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 295
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDE-FISLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + F L +L+KL L N
Sbjct: 296 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFN 344
Score = 31.5 bits (68), Expect = 8.2
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
+L L L +N L+ P L S ++L +S+N++ L+ +DL L A+ +++ N
Sbjct: 200 NLTHLSLKYNNLTVVPRNLPSSLEYLL---LSYNRIVKLAPEDLANLTALRVLDVGGNCR 256
Query: 434 HCD 436
CD
Sbjct: 257 RCD 259
>AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein.
Length = 709
Score = 75.8 bits (178), Expect = 4e-13
Identities = 45/152 (29%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L++L++ N+ + SI ++F GL +L L L+HN +T + F L L L ++ NH+
Sbjct: 151 DLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHL 210
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSR-LFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++S TF L SL L+L NN ++ L + L + + +L LDL N + +L F
Sbjct: 211 SRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISC 270
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+L + R+ + +N + + +L+E L
Sbjct: 271 SNLTVLVMRKNKINHLNENTFAPLQKLDEFSL 302
Score = 73.3 bits (172), Expect = 2e-12
Identities = 64/240 (26%), Positives = 110/240 (45%), Gaps = 7/240 (2%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ ++L N + + D F+ +L +L+L +N I +S FR L SL L L++N+I
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI-NTQIYHLV 226
+ L +F L +L L + DN L+ ++P F + L + +L R+ + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
PRL LDL N L + FIS L L + N+++ + +N F ++L +L
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLE--- 303
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQ 346
++SH +F +AP V S K N G + N +A ++Q
Sbjct: 304 --GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKP-NTDGISSLENLLASIIQ 360
Score = 68.1 bits (159), Expect = 8e-11
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F +L+ L L +N +TS+ FRGL +LT+L+L HN I + F L L+ LI+
Sbjct: 146 FKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLII 205
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDL-NPEVFKDIQHLRIFKCRRCLLRRINTQ 221
+N +S + F L L +L L +N LT L + + + + L + +
Sbjct: 206 EDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNL 265
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ L L + +N +L + F L++L + L+G ++S I MF
Sbjct: 266 TFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQRMF 315
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/77 (31%), Positives = 36/77 (46%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
+ L L+L N++ ++ F NLT L + N I ++ TF L L L
Sbjct: 246 MPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGI 305
Query: 166 QISTLVSRLFRMLAKLS 182
+IS + R+FR L LS
Sbjct: 306 EISNIQQRMFRPLMNLS 322
Score = 31.5 bits (68), Expect = 8.2
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 372 NEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ ++ A+ L WN + + P LQ+L + +NK+ ++S + L ++ ++ L N
Sbjct: 125 SSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHN 184
>AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein.
Length = 1032
Score = 75.8 bits (178), Expect = 4e-13
Identities = 65/222 (29%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + ++ + + SF L L L+L++N+ V NF + +L
Sbjct: 515 SQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 574
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 575 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 633
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 634 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALT 693
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 694 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 735
Score = 66.5 bits (155), Expect = 2e-10
Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 458 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 517
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ L + + +PRLE LDL N + F++ L+ L
Sbjct: 518 LPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 577
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 578 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 636
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 637 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNQLKALTNG 695
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 696 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 755
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 756 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 798
Score = 59.3 bits (137), Expect = 4e-08
Identities = 74/286 (25%), Positives = 118/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L +
Sbjct: 271 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAL 330
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 331 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 390
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 391 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 450
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 451 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 509
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 510 QAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYN 555
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 568 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 627 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 687 NQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 746
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 747 PLASALQILDVSAN 760
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/188 (29%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L++N++
Sbjct: 477 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLY 536
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 537 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 596
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 597 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 655
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 656 QVLRLRDN 663
Score = 44.0 bits (99), Expect = 0.001
Identities = 61/229 (26%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 120 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 179
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL +LT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 180 YKNPCRQALEVAPGALLGLGSLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 235
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 236 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 295
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDEFI-SLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + + L +L+KL L N
Sbjct: 296 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKALQGLTQLRKLNLSFN 344
>AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 form
B protein.
Length = 975
Score = 75.8 bits (178), Expect = 4e-13
Identities = 65/222 (29%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + ++ + + SF L L L+L++N+ V NF + +L
Sbjct: 458 SQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 517
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 518 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 576
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 577 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALT 636
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 637 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 678
Score = 66.5 bits (155), Expect = 2e-10
Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 401 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 460
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ L + + +PRLE LDL N + F++ L+ L
Sbjct: 461 LPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 520
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 521 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 579
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 580 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNQLKALTNG 638
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 639 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 698
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 699 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 741
Score = 61.7 bits (143), Expect = 7e-09
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L + F
Sbjct: 214 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAF 273
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 274 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 333
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 334 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 393
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 394 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 452
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 453 QAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYN 498
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 511 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 569
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 570 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 629
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 630 NQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 689
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 690 PLASALQILDVSAN 703
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/188 (29%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L++N++
Sbjct: 420 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLY 479
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 480 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 539
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 540 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 598
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 599 QVLRLRDN 606
Score = 47.2 bits (107), Expect = 2e-04
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 63 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 122
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL NLT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 123 YKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 178
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 179 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 238
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDE-FISLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + F L +L+KL L N
Sbjct: 239 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFN 287
Score = 31.5 bits (68), Expect = 8.2
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
+L L L +N L+ P L S ++L +S+N++ L+ +DL L A+ +++ N
Sbjct: 143 NLTHLSLKYNNLTVVPRNLPSSLEYLL---LSYNRIVKLAPEDLANLTALRVLDVGGNCR 199
Query: 434 HCD 436
CD
Sbjct: 200 RCD 202
>AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 form
A protein.
Length = 1032
Score = 75.8 bits (178), Expect = 4e-13
Identities = 65/222 (29%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + ++ + + SF L L L+L++N+ V NF + +L
Sbjct: 515 SQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 574
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 575 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 633
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 634 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALT 693
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 694 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 735
Score = 66.5 bits (155), Expect = 2e-10
Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 458 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 517
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ L + + +PRLE LDL N + F++ L+ L
Sbjct: 518 LPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 577
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 578 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 636
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 637 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNQLKALTNG 695
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 696 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 755
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 756 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 798
Score = 61.7 bits (143), Expect = 7e-09
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L + F
Sbjct: 271 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAF 330
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 331 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 390
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 391 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 450
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 451 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 509
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 510 QAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYN 555
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 568 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 627 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 687 NQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 746
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 747 PLASALQILDVSAN 760
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/188 (29%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L++N++
Sbjct: 477 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLY 536
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 537 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 596
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 597 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 655
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 656 QVLRLRDN 663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 120 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 179
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL NLT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 180 YKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 235
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 236 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 295
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDE-FISLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + F L +L+KL L N
Sbjct: 296 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFN 344
Score = 31.5 bits (68), Expect = 8.2
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
+L L L +N L+ P L S ++L +S+N++ L+ +DL L A+ +++ N
Sbjct: 200 NLTHLSLKYNNLTVVPRNLPSSLEYLL---LSYNRIVKLAPEDLANLTALRVLDVGGNCR 256
Query: 434 HCD 436
CD
Sbjct: 257 RCD 259
>AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 75.8 bits (178), Expect = 4e-13
Identities = 65/222 (29%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + ++ + + SF L L L+L++N+ V NF + +L
Sbjct: 515 SQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 574
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 575 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 633
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 634 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALT 693
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 694 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 735
Score = 66.5 bits (155), Expect = 2e-10
Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 458 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 517
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ L + + +PRLE LDL N + F++ L+ L
Sbjct: 518 LPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 577
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 578 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 636
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 637 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNQLKALTNG 695
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 696 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 755
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 756 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 798
Score = 61.7 bits (143), Expect = 7e-09
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L + F
Sbjct: 271 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAF 330
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 331 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 390
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 391 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 450
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 451 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 509
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 510 QAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYN 555
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 568 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 627 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 687 NQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 746
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 747 PLASALQILDVSAN 760
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/188 (29%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L++N++
Sbjct: 477 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLY 536
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 537 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 596
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 597 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 655
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 656 QVLRLRDN 663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 120 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 179
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL NLT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 180 YKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 235
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 236 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 295
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDE-FISLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + F L +L+KL L N
Sbjct: 296 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFN 344
Score = 31.5 bits (68), Expect = 8.2
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
+L L L +N L+ P L S ++L +S+N++ L+ +DL L A+ +++ N
Sbjct: 200 NLTHLSLKYNNLTVVPRNLPSSLEYLL---LSYNRIVKLAPEDLANLTALRVLDVGGNCR 256
Query: 434 HCD 436
CD
Sbjct: 257 RCD 259
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 75.4 bits (177), Expect = 5e-13
Identities = 55/194 (28%), Positives = 86/194 (44%)
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
NLT + A+ +G L ELHL N +E +S E R + L+ L L N ++ L LF+
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQA 138
Query: 178 LAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
A L L L +N L L ++ L LR++ + L LDLGEN
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 238 LFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXX 297
+ L D +L++L L+GN+L V+ ++ +L L L+ N+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 298 XXXXXXXDISHNKI 311
D+S+N +
Sbjct: 259 LRQLDMLDLSNNSL 272
Score = 67.3 bits (157), Expect = 1e-10
Identities = 53/181 (29%), Positives = 79/181 (43%)
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
G L+ L+L+ N L S+ + R + L L L N + + F+ +L TL+L
Sbjct: 90 GASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKE 149
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
NQ+ L L L LDLS N L L P + + LR L + +
Sbjct: 150 NQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLR 209
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+LE L L N + L D + L+ L L+GN+L+ + F R+L +L LS
Sbjct: 210 GPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSN 269
Query: 285 N 285
N
Sbjct: 270 N 270
Score = 64.9 bits (151), Expect = 7e-10
Identities = 49/187 (26%), Positives = 81/187 (43%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ELH+ ++ + S+ + LRVL+LT N LT + F+ L L L N +E
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ L +L L L+ N++ L L L LDL +N L L P++ +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L+ + + P L L L N + + F L++L L L N L+
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 265 VIVDNMF 271
+ + ++
Sbjct: 274 SVPEGLW 280
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 2/203 (0%)
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L + +KL L LS N L L+PE + + LR+ R L + ++
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+ L L EN + L LK L L L GN+L + + L L L N+
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQ 346
+ NK+ P D L+ + +GN L A Q
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPD-LRYLFLNGNKL-ARVAAGAFQ 257
Query: 347 ILPEIHGVGLANLSLQEIPQNFF 369
L ++ + L+N SL +P+ +
Sbjct: 258 GLRQLDMLDLSNNSLASVPEGLW 280
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 2/167 (1%)
Query: 71 TIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
++ P F +P P LR L + + + + F L L L N L + GL
Sbjct: 106 SLSPEFLRPVP--QLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGL 163
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L N + ++ + T L+TL L NQ+ TL L R +L L L N
Sbjct: 164 KALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L L ++ LR L R+ + + +L+ LDL N
Sbjct: 224 LQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/151 (23%), Positives = 66/151 (43%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L ++ ++ + + + + L+ L L++N + +L R + +L +LDL+ N LT L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
P +F+ L + L + H + L LDL N + L + L+
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L NQL + ++ +L L L N+
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 77/187 (41%), Gaps = 2/187 (1%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L+EL L N + L+ + + +L+ L L N L+ + +F + L L L N+
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQL 152
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQI 347
D+S N++ + A L+T++ N L ++
Sbjct: 153 EVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFT-LLRTLDLGENQLETLPPDLLRGP 211
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L ++ + L LQ + ++ L L L+ NKL+R + L LD+S+N
Sbjct: 212 L-QLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 408 KLQTLSE 414
L ++ E
Sbjct: 271 SLASVPE 277
Score = 34.7 bits (76), Expect = 0.88
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 331 FSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPF 390
F+ +LP N +LQ ++ + L++ L+ + F L LDL+ N L+ P
Sbjct: 78 FNLTHLPAN----LLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPP 133
Query: 391 KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L + N+L+ L L L+A+ ++L N
Sbjct: 134 GLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
Score = 31.5 bits (68), Expect = 8.2
Identities = 23/87 (26%), Positives = 39/87 (44%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
L+ +P++ + L +L +P F + L L L N+L L K L LD+
Sbjct: 112 LRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDL 171
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKN 431
S N+L+ L L + ++L +N
Sbjct: 172 SGNRLRKLPPGLLANFTLLRTLDLGEN 198
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 75.4 bits (177), Expect = 5e-13
Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 17/343 (4%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +++ S+ S L+ LR+L+L HN L + + +R L +LT L+L N
Sbjct: 146 VNLMTLALSENSLTSLPD-SLDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNR 203
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + + ++L+ L L + N+I L + + L L LD++ N L L E+
Sbjct: 204 ITTVEKD-IKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKEIGNCT 261
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
Q + LL +T I +L L L L N + L++L L+ N
Sbjct: 262 QITNLDLQHNELLDLPDT-IGNL-SSLSRLGLRYNRLSAIPRS-LAKCSALEELNLENNN 318
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + +++ +L+ LTL+RN ++ HN+I++ F+
Sbjct: 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L +N N L + + + + LA L +IP++ L L LS
Sbjct: 379 -KVLSKLNMKDNQL--TSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS-LEVLILSN 434
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ-----DLQRL 420
N L + P L + K L+ LD+ NKL++L + DLQ+L
Sbjct: 435 NLLKKLPHGLGNLRK-LRELDLEENKLESLPNEIAYLKDLQKL 476
Score = 71.7 bits (168), Expect = 6e-12
Identities = 81/340 (23%), Positives = 153/340 (45%), Gaps = 12/340 (3%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
+SN I + + +N L+L+ ++ ++ + + L LTEL+L N ++ + +E
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV- 142
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L TL L+ N +++L L L KL +LDL N L ++ P V + L R
Sbjct: 143 GCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLREI-PSVVYRLDSLTTLYLR 200
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + I +L +L L + EN K L + E L L L + NQL + +
Sbjct: 201 FNRITTVEKDIKNL-SKLSMLSIRENKIKQLPA-EIGELCNLITLDVAHNQLEHLPKEI- 257
Query: 272 GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINF 331
G ++ L L N + +N++ ++ A +L+ +N
Sbjct: 258 GNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG-LRYNRLSAIP-RSLAKC-SALEELNL 314
Query: 332 SGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
NN+ ++ L L +++ + LA Q P + + +L++ N++++ PF
Sbjct: 315 ENNNISTLPESL-LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ S+ K L +L++ N+L +L D ++ E+NL N
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVELNLATN 412
Score = 64.5 bits (150), Expect = 9e-10
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ F + L++ ++ + I F + L LN+ N LTS+ D F ++ EL+L
Sbjct: 351 PSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNL 409
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N + ++ E L SL+ LIL+NN + L L L KL LDL +N L L E+
Sbjct: 410 ATNQLTKI-PEDVSGLVSLEVLILSNNLLKKLPHGLGN-LRKLRELDLEENKLESLPNEI 467
Query: 199 --FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
KD+Q L + + L R I HL L L LGENL +L +E +L+ L++L
Sbjct: 468 AYLKDLQKLVLTNNQLTTLPR---GIGHLT-NLTHLGLGENLLTHL-PEEIGTLENLEEL 522
Query: 257 KLDGN 261
L+ N
Sbjct: 523 YLNDN 527
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LREL + + + S+ + L++L+ L LT+N LT++ L NLT L L N +
Sbjct: 450 LRELDLEENKLESLPNEIAY-LKDLQKLVLTNNQLTTLPR-GIGHLTNLTHLGLGENLLT 507
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+ E L +L+ L L +N + + +KLSI+ + + PL+ L P++
Sbjct: 508 HLPEE-IGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQI 560
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 75.4 bits (177), Expect = 5e-13
Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 17/343 (4%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +++ S+ S L+ LR+L+L HN L + + +R L +LT L+L N
Sbjct: 146 VNLMTLALSENSLTSLPD-SLDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNR 203
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + + ++L+ L L + N+I L + + L L LD++ N L L E+
Sbjct: 204 ITTVEKD-IKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKEIGNCT 261
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
Q + LL +T I +L L L L N + L++L L+ N
Sbjct: 262 QITNLDLQHNELLDLPDT-IGNL-SSLSRLGLRYNRLSAIPRS-LAKCSALEELNLENNN 318
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + +++ +L+ LTL+RN ++ HN+I++ F+
Sbjct: 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L +N N L + + + + LA L +IP++ L L LS
Sbjct: 379 -KVLSKLNMKDNQL--TSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS-LEVLILSN 434
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ-----DLQRL 420
N L + P L + K L+ LD+ NKL++L + DLQ+L
Sbjct: 435 NLLKKLPHGLGNLRK-LRELDLEENKLESLPNEIAYLKDLQKL 476
Score = 71.7 bits (168), Expect = 6e-12
Identities = 81/340 (23%), Positives = 153/340 (45%), Gaps = 12/340 (3%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
+SN I + + +N L+L+ ++ ++ + + L LTEL+L N ++ + +E
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV- 142
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L TL L+ N +++L L L KL +LDL N L ++ P V + L R
Sbjct: 143 GCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLREI-PSVVYRLDSLTTLYLR 200
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + I +L +L L + EN K L + E L L L + NQL + +
Sbjct: 201 FNRITTVEKDIKNL-SKLSMLSIRENKIKQLPA-EIGELCNLITLDVAHNQLEHLPKEI- 257
Query: 272 GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINF 331
G ++ L L N + +N++ ++ A +L+ +N
Sbjct: 258 GNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG-LRYNRLSAIP-RSLAKC-SALEELNL 314
Query: 332 SGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
NN+ ++ L L +++ + LA Q P + + +L++ N++++ PF
Sbjct: 315 ENNNISTLPESL-LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ S+ K L +L++ N+L +L D ++ E+NL N
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVELNLATN 412
Score = 64.5 bits (150), Expect = 9e-10
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ F + L++ ++ + I F + L LN+ N LTS+ D F ++ EL+L
Sbjct: 351 PSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNL 409
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N + ++ E L SL+ LIL+NN + L L L KL LDL +N L L E+
Sbjct: 410 ATNQLTKI-PEDVSGLVSLEVLILSNNLLKKLPHGLGN-LRKLRELDLEENKLESLPNEI 467
Query: 199 --FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
KD+Q L + + L R I HL L L LGENL +L +E +L+ L++L
Sbjct: 468 AYLKDLQKLVLTNNQLTTLPR---GIGHLT-NLTHLGLGENLLTHL-PEEIGTLENLEEL 522
Query: 257 KLDGN 261
L+ N
Sbjct: 523 YLNDN 527
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LREL + + + S+ + L++L+ L LT+N LT++ L NLT L L N +
Sbjct: 450 LRELDLEENKLESLPNEIAY-LKDLQKLVLTNNQLTTLPR-GIGHLTNLTHLGLGENLLT 507
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+ E L +L+ L L +N + + +KLSI+ + + PL+ L P++
Sbjct: 508 HLPEE-IGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQI 560
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 75.4 bits (177), Expect = 5e-13
Identities = 55/194 (28%), Positives = 86/194 (44%)
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
NLT + A+ +G L ELHL N +E +S E R + L+ L L N ++ L LF+
Sbjct: 79 NLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQA 138
Query: 178 LAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
A L L L +N L L ++ L LR++ + L LDLGEN
Sbjct: 139 SATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGEN 198
Query: 238 LFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXX 297
+ L D +L++L L+GN+L V+ ++ +L L L+ N+
Sbjct: 199 QLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQG 258
Query: 298 XXXXXXXDISHNKI 311
D+S+N +
Sbjct: 259 LRQLDMLDLSNNSL 272
Score = 67.3 bits (157), Expect = 1e-10
Identities = 53/181 (29%), Positives = 79/181 (43%)
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
G L+ L+L+ N L S+ + R + L L L N + + F+ +L TL+L
Sbjct: 90 GASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKE 149
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
NQ+ L L L LDLS N L L P + + LR L + +
Sbjct: 150 NQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLR 209
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+LE L L N + L D + L+ L L+GN+L+ + F R+L +L LS
Sbjct: 210 GPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSN 269
Query: 285 N 285
N
Sbjct: 270 N 270
Score = 64.9 bits (151), Expect = 7e-10
Identities = 49/187 (26%), Positives = 81/187 (43%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ELH+ ++ + S+ + LRVL+LT N LT + F+ L L L N +E
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ L +L L L+ N++ L L L LDL +N L L P++ +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L L+ + + P L L L N + + F L++L L L N L+
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 265 VIVDNMF 271
+ + ++
Sbjct: 274 SVPEGLW 280
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 2/203 (0%)
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
++ L + L + +KL L LS N L L+PE + + LR+ R L + ++
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+ L L EN + L LK L L L GN+L + + L L L N+
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQ 346
+ NK+ P D L+ + +GN L A Q
Sbjct: 200 LETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPD-LRYLFLNGNKL-ARVAAGAFQ 257
Query: 347 ILPEIHGVGLANLSLQEIPQNFF 369
L ++ + L+N SL +P+ +
Sbjct: 258 GLRQLDMLDLSNNSLASVPEGLW 280
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 2/167 (1%)
Query: 71 TIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL 130
++ P F +P P LR L + + + + F L L L N L + GL
Sbjct: 106 SLSPEFLRPVP--QLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGL 163
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L N + ++ + T L+TL L NQ+ TL L R +L L L N
Sbjct: 164 KALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L L ++ LR L R+ + + +L+ LDL N
Sbjct: 224 LQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/151 (23%), Positives = 66/151 (43%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L ++ ++ + + + + L+ L L++N + +L R + +L +LDL+ N LT L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
P +F+ L + L + H + L LDL N + L + L+
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L NQL + ++ +L L L N+
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 77/187 (41%), Gaps = 2/187 (1%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L+EL L N + L+ + + +L+ L L N L+ + +F + L L L N+
Sbjct: 93 KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQL 152
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQI 347
D+S N++ + A L+T++ N L ++
Sbjct: 153 EVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFT-LLRTLDLGENQLETLPPDLLRGP 211
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L ++ + L LQ + ++ L L L+ NKL+R + L LD+S+N
Sbjct: 212 L-QLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN 270
Query: 408 KLQTLSE 414
L ++ E
Sbjct: 271 SLASVPE 277
Score = 34.7 bits (76), Expect = 0.88
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 331 FSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPF 390
F+ +LP N +LQ ++ + L++ L+ + F L LDL+ N L+ P
Sbjct: 78 FNLTHLPAN----LLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPP 133
Query: 391 KLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
L + L L + N+L+ L L L+A+ ++L N
Sbjct: 134 GLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
Score = 31.5 bits (68), Expect = 8.2
Identities = 23/87 (26%), Positives = 39/87 (44%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
L+ +P++ + L +L +P F + L L L N+L L K L LD+
Sbjct: 112 LRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDL 171
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKN 431
S N+L+ L L + ++L +N
Sbjct: 172 SGNRLRKLPPGLLANFTLLRTLDLGEN 198
>AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 75.4 bits (177), Expect = 5e-13
Identities = 65/222 (29%), Positives = 103/222 (46%), Gaps = 14/222 (6%)
Query: 77 TQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLT---SVVADNFRGLINL 133
+Q P L+ L + + + + SF L L L+L++N+ V NF + +L
Sbjct: 515 SQFLPLTGLQVLDLSRNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHL 574
Query: 134 TEL-HLD--HNHIEQMSSETFRHLTSLKTLILANNQIS------TLVSRLFRMLAKLSIL 184
L HL HN+I S+ TSL+ L + N + L F+ L+ L L
Sbjct: 575 RTLRHLSLAHNNIHSQVSQQLCS-TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWL 633
Query: 185 DLSDNPLTDLNPEVFKDI-QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
DLS N L L P+ +++ + L++ + R L H +P+LE LDL N K LT
Sbjct: 634 DLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNRLKALT 693
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + RL++L + N +S + F + +EL L LS N
Sbjct: 694 NGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSAN 735
Score = 68.1 bits (159), Expect = 8e-11
Identities = 91/345 (26%), Positives = 144/345 (41%), Gaps = 22/345 (6%)
Query: 143 IEQMSSETFR-HLTSLK-TLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVF 199
++ SSE FR + ++L TL L+ N + T+ +F L+ L L LS N ++ +N F
Sbjct: 458 VDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQF 517
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD-----EFIS-LKRL 253
+ L++ R L + + +PRLE LDL N + F++ L+ L
Sbjct: 518 LPLTGLQVLDLSRNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTL 577
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX------DIS 307
+ L L N + V + L L S N D+S
Sbjct: 578 RHLSLAHNNIHSQVSQQLC-STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLS 636
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
N++ QT + SL+ + N L + L LP++ + LA L+ +
Sbjct: 637 QNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS-LHFLPKLEVLDLAGNRLKALTNG 695
Query: 368 FFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL-EAIAEV 426
L LD+S N +S SK K L+ L++S N L+T+ L A+ +
Sbjct: 696 SLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQIL 755
Query: 427 NLMKNNWHCDQCSASNM--LLYMTTTVLNSTIRVLKCHSPLRLRG 469
++ N HC C A+ M LL + V RV KC SP +L+G
Sbjct: 756 DVSANPLHC-ACGAAFMDFLLEVQAAVPGLPSRV-KCGSPGQLQG 798
Score = 61.3 bits (142), Expect = 9e-09
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 21/286 (7%)
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEVF 199
H Q+ +TF HL+ L+ L+L ++ +S L + FR L L +LDLS+N L + F
Sbjct: 271 HFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAF 330
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVP------RLEELDLGENLFKYLTSDEFISLKRL 253
+ + LR +R++ L P L+ELD+ F+ L L RL
Sbjct: 331 QGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARL 390
Query: 254 KKLKLDGNQLSVIVDNMFGRNRE---LHVLTLSRNRXXXXXXXXXXXXXXXXX------- 303
L+ Q++ I G R L + LS NR
Sbjct: 391 PMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP 450
Query: 304 XDISHNKIDRFHLQTFAPVVDSLK-TINFSGNNLPLNEIAIVLQILPEIHGVGLA-NLSL 361
D++ +D + F P +L T++ S NNL + + Q L + + L+ N
Sbjct: 451 GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQ-LSHLQCLRLSHNCIS 509
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
Q + + F L LDLS NKL + ++ L+ LD+S+N
Sbjct: 510 QAVNGSQFLPLTGLQVLDLSRNKLDLYHEHSFTELPRLEALDLSYN 555
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 101 FSFWG-LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSET------FRH 153
FSF L+ LR L+L HNN+ S V+ +L L N + M +E F+
Sbjct: 568 FSFVAHLRTLRHLSLAHNNIHSQVSQQLCST-SLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAK-LSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L+ L L L+ N++ TL+ + R L K L +L L DN L + L +
Sbjct: 627 LSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFG 272
L+ + RL LD+ N ++ F K L++L L N L + + FG
Sbjct: 687 NRLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFG 746
Query: 273 -RNRELHVLTLSRN 285
L +L +S N
Sbjct: 747 PLASALQILDVSAN 760
Score = 48.4 bits (110), Expect = 7e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 15/188 (7%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ-MSSETFRHLTSLKTLILANNQISTL 170
L+L+ NNL +V + F L +L L L HN I Q ++ F LT L+ L L+ N++
Sbjct: 477 LDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSRNKLDLY 536
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEV---FKDIQHLRIFKCRRCLLRRINTQIYHLV- 226
F L +L LDLS N V F + HLR + I++Q+ +
Sbjct: 537 HEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLC 596
Query: 227 -PRLEELDLGENLFKYLTSDE------FISLKRLKKLKLDGNQLSVIVDNMFGRN--REL 277
L LD N ++ ++ F L L L L N+L ++ RN + L
Sbjct: 597 STSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTL-RNLPKSL 655
Query: 278 HVLTLSRN 285
VL L N
Sbjct: 656 QVLRLRDN 663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 31/229 (13%)
Query: 60 IAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-- 117
+A P L+ I T PA +L L + ++N+ + S GL LR L + N
Sbjct: 120 LAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCY 179
Query: 118 ------NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHL-TSLKTLILANNQISTL 170
V GL NLT L L +N++ + R+L +SL+ L+L+ N+I L
Sbjct: 180 YKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP----RNLPSSLEYLLLSYNRIVKL 235
Query: 171 VSRLFRMLAKLSILDL---------SDNPLTD-------LNPEVFKDIQHLRIFKCRRCL 214
L L +LD+ + NP + L+P+ F + L +
Sbjct: 236 APEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSS 295
Query: 215 LRRINTQIYHLVPRLEELDLGEN-LFKYLTSDE-FISLKRLKKLKLDGN 261
L +N + + L LDL EN L+K +T + F L +L+KL L N
Sbjct: 296 LSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFN 344
Score = 31.5 bits (68), Expect = 8.2
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 374 HLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNW 433
+L L L +N L+ P L S ++L +S+N++ L+ +DL L A+ +++ N
Sbjct: 200 NLTHLSLKYNNLTVVPRNLPSSLEYLL---LSYNRIVKLAPEDLANLTALRVLDVGGNCR 256
Query: 434 HCD 436
CD
Sbjct: 257 RCD 259
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 75.4 bits (177), Expect = 5e-13
Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 17/343 (4%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +++ S+ S L+ LR+L+L HN L + + +R L +LT L+L N
Sbjct: 146 VNLMTLALSENSLTSLPD-SLDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNR 203
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + + ++L+ L L + N+I L + + L L LD++ N L L E+
Sbjct: 204 ITTVEKD-IKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKEIGNCT 261
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
Q + LL +T I +L L L L N + L++L L+ N
Sbjct: 262 QITNLDLQHNELLDLPDT-IGNL-SSLSRLGLRYNRLSAIPRS-LAKCSALEELNLENNN 318
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + +++ +L+ LTL+RN ++ HN+I++ F+
Sbjct: 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L +N N L + + + + LA L +IP++ L L LS
Sbjct: 379 -KVLSKLNMKDNQL--TSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS-LEVLILSN 434
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ-----DLQRL 420
N L + P L + K L+ LD+ NKL++L + DLQ+L
Sbjct: 435 NLLKKLPHGLGNLRK-LRELDLEENKLESLPNEIAYLKDLQKL 476
Score = 71.7 bits (168), Expect = 6e-12
Identities = 81/340 (23%), Positives = 153/340 (45%), Gaps = 12/340 (3%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
+SN I + + +N L+L+ ++ ++ + + L LTEL+L N ++ + +E
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV- 142
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L TL L+ N +++L L L KL +LDL N L ++ P V + L R
Sbjct: 143 GCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLREI-PSVVYRLDSLTTLYLR 200
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + I +L +L L + EN K L + E L L L + NQL + +
Sbjct: 201 FNRITTVEKDIKNL-SKLSMLSIRENKIKQLPA-EIGELCNLITLDVAHNQLEHLPKEI- 257
Query: 272 GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINF 331
G ++ L L N + +N++ ++ A +L+ +N
Sbjct: 258 GNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG-LRYNRLSAIP-RSLAKC-SALEELNL 314
Query: 332 SGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
NN+ ++ L L +++ + LA Q P + + +L++ N++++ PF
Sbjct: 315 ENNNISTLPESL-LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ S+ K L +L++ N+L +L D ++ E+NL N
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVELNLATN 412
Score = 64.5 bits (150), Expect = 9e-10
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ F + L++ ++ + I F + L LN+ N LTS+ D F ++ EL+L
Sbjct: 351 PSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNL 409
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N + ++ E L SL+ LIL+NN + L L L KL LDL +N L L E+
Sbjct: 410 ATNQLTKI-PEDVSGLVSLEVLILSNNLLKKLPHGLGN-LRKLRELDLEENKLESLPNEI 467
Query: 199 --FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
KD+Q L + + L R I HL L L LGENL +L +E +L+ L++L
Sbjct: 468 AYLKDLQKLVLTNNQLTTLPR---GIGHLT-NLTHLGLGENLLTHL-PEEIGTLENLEEL 522
Query: 257 KLDGN 261
L+ N
Sbjct: 523 YLNDN 527
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LREL + + + S+ + L++L+ L LT+N LT++ L NLT L L N +
Sbjct: 450 LRELDLEENKLESLPNEIAY-LKDLQKLVLTNNQLTTLPR-GIGHLTNLTHLGLGENLLT 507
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+ E L +L+ L L +N + + +KLSI+ + + PL+ L P++
Sbjct: 508 HLPEE-IGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQI 560
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 75.4 bits (177), Expect = 5e-13
Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 17/343 (4%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +++ S+ S L+ LR+L+L HN L + + +R L +LT L+L N
Sbjct: 146 VNLMTLALSENSLTSLPD-SLDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNR 203
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + + ++L+ L L + N+I L + + L L LD++ N L L E+
Sbjct: 204 ITTVEKD-IKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKEIGNCT 261
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
Q + LL +T I +L L L L N + L++L L+ N
Sbjct: 262 QITNLDLQHNELLDLPDT-IGNL-SSLSRLGLRYNRLSAIPRS-LAKCSALEELNLENNN 318
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + +++ +L+ LTL+RN ++ HN+I++ F+
Sbjct: 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L +N N L + + + + LA L +IP++ L L LS
Sbjct: 379 -KVLSKLNMKDNQL--TSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS-LEVLILSN 434
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ-----DLQRL 420
N L + P L + K L+ LD+ NKL++L + DLQ+L
Sbjct: 435 NLLKKLPHGLGNLRK-LRELDLEENKLESLPNEIAYLKDLQKL 476
Score = 71.7 bits (168), Expect = 6e-12
Identities = 81/340 (23%), Positives = 153/340 (45%), Gaps = 12/340 (3%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
+SN I + + +N L+L+ ++ ++ + + L LTEL+L N ++ + +E
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV- 142
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L TL L+ N +++L L L KL +LDL N L ++ P V + L R
Sbjct: 143 GCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLREI-PSVVYRLDSLTTLYLR 200
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + I +L +L L + EN K L + E L L L + NQL + +
Sbjct: 201 FNRITTVEKDIKNL-SKLSMLSIRENKIKQLPA-EIGELCNLITLDVAHNQLEHLPKEI- 257
Query: 272 GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINF 331
G ++ L L N + +N++ ++ A +L+ +N
Sbjct: 258 GNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG-LRYNRLSAIP-RSLAKC-SALEELNL 314
Query: 332 SGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
NN+ ++ L L +++ + LA Q P + + +L++ N++++ PF
Sbjct: 315 ENNNISTLPESL-LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ S+ K L +L++ N+L +L D ++ E+NL N
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVELNLATN 412
Score = 64.5 bits (150), Expect = 9e-10
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ F + L++ ++ + I F + L LN+ N LTS+ D F ++ EL+L
Sbjct: 351 PSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNL 409
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N + ++ E L SL+ LIL+NN + L L L KL LDL +N L L E+
Sbjct: 410 ATNQLTKI-PEDVSGLVSLEVLILSNNLLKKLPHGLGN-LRKLRELDLEENKLESLPNEI 467
Query: 199 --FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
KD+Q L + + L R I HL L L LGENL +L +E +L+ L++L
Sbjct: 468 AYLKDLQKLVLTNNQLTTLPR---GIGHLT-NLTHLGLGENLLTHL-PEEIGTLENLEEL 522
Query: 257 KLDGN 261
L+ N
Sbjct: 523 YLNDN 527
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LREL + + + S+ + L++L+ L LT+N LT++ L NLT L L N +
Sbjct: 450 LRELDLEENKLESLPNEIAY-LKDLQKLVLTNNQLTTLPR-GIGHLTNLTHLGLGENLLT 507
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+ E L +L+ L L +N + + +KLSI+ + + PL+ L P++
Sbjct: 508 HLPEE-IGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQI 560
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 75.4 bits (177), Expect = 5e-13
Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 17/343 (4%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL L + +++ S+ S L+ LR+L+L HN L + + +R L +LT L+L N
Sbjct: 148 VNLMTLALSENSLTSLPD-SLDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNR 205
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + + ++L+ L L + N+I L + + L L LD++ N L L E+
Sbjct: 206 ITTVEKD-IKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKEIGNCT 263
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
Q + LL +T I +L L L L N + L++L L+ N
Sbjct: 264 QITNLDLQHNELLDLPDT-IGNL-SSLSRLGLRYNRLSAIPRS-LAKCSALEELNLENNN 320
Query: 263 LSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV 322
+S + +++ +L+ LTL+RN ++ HN+I++ F+
Sbjct: 321 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 380
Query: 323 VDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSW 382
L +N N L + + + + LA L +IP++ L L LS
Sbjct: 381 -KVLSKLNMKDNQL--TSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS-LEVLILSN 436
Query: 383 NKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ-----DLQRL 420
N L + P L + K L+ LD+ NKL++L + DLQ+L
Sbjct: 437 NLLKKLPHGLGNLRK-LRELDLEENKLESLPNEIAYLKDLQKL 478
Score = 71.7 bits (168), Expect = 6e-12
Identities = 81/340 (23%), Positives = 153/340 (45%), Gaps = 12/340 (3%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
+SN I + + +N L+L+ ++ ++ + + L LTEL+L N ++ + +E
Sbjct: 87 SSNAEVIKELNKCREENSMRLDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV- 144
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L TL L+ N +++L L L KL +LDL N L ++ P V + L R
Sbjct: 145 GCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLREI-PSVVYRLDSLTTLYLR 202
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + I +L +L L + EN K L + E L L L + NQL + +
Sbjct: 203 FNRITTVEKDIKNL-SKLSMLSIRENKIKQLPA-EIGELCNLITLDVAHNQLEHLPKEI- 259
Query: 272 GRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINF 331
G ++ L L N + +N++ ++ A +L+ +N
Sbjct: 260 GNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG-LRYNRLSAIP-RSLAKC-SALEELNL 316
Query: 332 SGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
NN+ ++ L L +++ + LA Q P + + +L++ N++++ PF
Sbjct: 317 ENNNISTLPESL-LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 375
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
+ S+ K L +L++ N+L +L D ++ E+NL N
Sbjct: 376 IFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVELNLATN 414
Score = 64.5 bits (150), Expect = 9e-10
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ F + L++ ++ + I F + L LN+ N LTS+ D F ++ EL+L
Sbjct: 353 PSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNL 411
Query: 139 DHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
N + ++ E L SL+ LIL+NN + L L L KL LDL +N L L E+
Sbjct: 412 ATNQLTKI-PEDVSGLVSLEVLILSNNLLKKLPHGLGN-LRKLRELDLEENKLESLPNEI 469
Query: 199 --FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
KD+Q L + + L R I HL L L LGENL +L +E +L+ L++L
Sbjct: 470 AYLKDLQKLVLTNNQLTTLPR---GIGHLT-NLTHLGLGENLLTHL-PEEIGTLENLEEL 524
Query: 257 KLDGN 261
L+ N
Sbjct: 525 YLNDN 529
Score = 41.5 bits (93), Expect = 0.008
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LREL + + + S+ + L++L+ L LT+N LT++ L NLT L L N +
Sbjct: 452 LRELDLEENKLESLPNEIAY-LKDLQKLVLTNNQLTTLPR-GIGHLTNLTHLGLGENLLT 509
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV 198
+ E L +L+ L L +N + + +KLSI+ + + PL+ L P++
Sbjct: 510 HLPEE-IGTLENLEELYLNDNPNLHSLPLELALCSKLSIMSIENCPLSHLPPQI 562
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 74.1 bits (174), Expect = 1e-12
Identities = 95/379 (25%), Positives = 150/379 (39%), Gaps = 14/379 (3%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIS--- 168
L+L+ N L S++A L L L N I + F+ LT L+ L LA+N+++
Sbjct: 54 LDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 113
Query: 169 TLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L + L +++ LDLS N L + L + + L L R+ + +P
Sbjct: 114 ALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
LE+LDL N+ + F L RL L L N L+ I D ++L VL LS N
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSL---QQLRVLDLSCNSI 230
Query: 288 XXXXXXXX-XXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIV 344
D+ NK+ H A + L +N S N LP
Sbjct: 231 EAFQTASQPQAEFQLTWLDLRENKL--LHFPDLA-ALPRLIYLNLSNNLIRLPTGPPQDS 287
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
I G LS + ++ L+ LDLS+N++ P L L L++
Sbjct: 288 KGIHAPSEGWSALPLSAPSGNASGRPLSQ-LLNLDLSYNEIELIPDSFLEHLTSLCFLNL 346
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSP 464
S N L+T + L L + ++L N + A + T + + +R L ++
Sbjct: 347 SRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTF 406
Query: 465 LRLRGATFGSLSFEQLDPC 483
L +L ++ PC
Sbjct: 407 ANLASLQRLNLQGNRVSPC 425
Score = 68.9 bits (161), Expect = 4e-11
Identities = 82/312 (26%), Positives = 131/312 (41%), Gaps = 16/312 (5%)
Query: 109 LRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ---MSSETFRHLTSLKTLILANN 165
LR L+L+ N ++ + F+ L +L L L HN + +S+ L + +L L+ N
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGN 134
Query: 166 QI-STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
+ S L+ RL L L L++N LT L F+D+ L +L I +
Sbjct: 135 SLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFE 194
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PRL L+L N LT SL++L+ L L N + E + L
Sbjct: 195 GLPRLTHLNLSRN---SLTCISDFSLQQLRVLDLSCNSIEAF-QTASQPQAEFQLTWLDL 250
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS--LKTINFSGNNLPLNEIA 342
++S+N I L T P DS + + + LPL+ +
Sbjct: 251 RENKLLHFPDLAALPRLIYLNLSNNLI---RLPT-GPPQDSKGIHAPSEGWSALPLSAPS 306
Query: 343 --IVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
+ L ++ + L+ ++ IP +F + L L+LS N L F + L L
Sbjct: 307 GNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLM 366
Query: 401 RLDISHNKLQTL 412
LD+SHN L+TL
Sbjct: 367 LLDLSHNALETL 378
Score = 41.9 bits (94), Expect = 0.006
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 12/196 (6%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P L L + + + I L +L LNL+ N L + A L L L L H
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL-NPE-- 197
N +E + R L SL+TL+L N + L F LA L L+L N ++ P+
Sbjct: 373 NALETLELGA-RALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEP 431
Query: 198 ------VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
F I LR + + + P L ELDL N + + L+
Sbjct: 432 GPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP-LTELDLSSNPGLEVATGALGGLE 490
Query: 252 -RLKKLKLDGNQLSVI 266
L+ L L GN L V+
Sbjct: 491 ASLEVLALQGNGLMVL 506
Score = 41.5 bits (93), Expect = 0.008
Identities = 68/299 (22%), Positives = 122/299 (40%), Gaps = 26/299 (8%)
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK---DIQHLRIFKCRRCL 214
+TL L+ NQ+ ++++ L LDLS N ++ L P F+ ++HL + R +
Sbjct: 52 ETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAM 111
Query: 215 LRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
++ +PR+ LDL G +L+ L L L L N L+ + + F
Sbjct: 112 ATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRD 171
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK---IDRFHLQTFAPV------VD 324
L L L N ++S N I F LQ + ++
Sbjct: 172 MPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIE 231
Query: 325 SLKTIN-----FSGNNLPLNEIAIV----LQILPEIHGVGLANLSLQEIPQNFFTYNEHL 375
+ +T + F L L E ++ L LP + + L+N +L +P ++ +
Sbjct: 232 AFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSN-NLIRLPTGPPQDSKGI 290
Query: 376 VALDLSWNKLS-RFPFKLLSKTKFLQ--RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
A W+ L P S Q LD+S+N+++ + + L+ L ++ +NL +N
Sbjct: 291 HAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRN 349
Score = 41.1 bits (92), Expect = 0.010
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 19/194 (9%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---------FRGLINLT 134
+LR L + + + + ++F L +L+ LNL N ++ + F G+ +L
Sbjct: 387 SLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLR 446
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTD 193
L L N IE + + F H T L L L++N + L + A L +L L N L
Sbjct: 447 SLSLVDNEIELLRAGAFLH-TPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMV 505
Query: 194 LNPEV--FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L ++ F ++ L + + R L + LE LDL N F L L+
Sbjct: 506 LQVDLPCFICLKRLNLAENRLSHLPAWTQAV-----SLEVLDLRNNSFSLLPGSAMGGLE 560
Query: 252 -RLKKLKLDGNQLS 264
L++L L GN LS
Sbjct: 561 TSLRRLYLQGNPLS 574
Score = 37.9 bits (84), Expect = 0.094
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
+L L+L N+LT + FR + L +L L N + + F L L L L+ N +
Sbjct: 150 SLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSL 209
Query: 168 STLVSRLFRMLAKLSILDLSDNPL 191
T +S L +L +LDLS N +
Sbjct: 210 -TCISDF--SLQQLRVLDLSCNSI 230
Score = 32.3 bits (70), Expect = 4.7
Identities = 34/163 (20%), Positives = 61/163 (37%), Gaps = 4/163 (2%)
Query: 276 ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNN 335
+ L LS N+ D+S N+I F + L+ ++ + N
Sbjct: 50 DTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTH-LEHLSLAHNR 108
Query: 336 LPLNEIAIV--LQILPEIHGVGLANLSLQE-IPQNFFTYNEHLVALDLSWNKLSRFPFKL 392
L + L LP + + L+ SL + + L L L+ N L+R
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 393 LSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L++LD+ N L + + + L + +NL +N+ C
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTC 211
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 74.1 bits (174), Expect = 1e-12
Identities = 95/379 (25%), Positives = 150/379 (39%), Gaps = 14/379 (3%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIS--- 168
L+L+ N L S++A L L L N I + F+ LT L+ L LA+N+++
Sbjct: 54 LDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 113
Query: 169 TLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L + L +++ LDLS N L + L + + L L R+ + +P
Sbjct: 114 ALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
LE+LDL N+ + F L RL L L N L+ I D ++L VL LS N
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSL---QQLRVLDLSCNSI 230
Query: 288 XXXXXXXX-XXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIV 344
D+ NK+ H A + L +N S N LP
Sbjct: 231 EAFQTASQPQAEFQLTWLDLRENKL--LHFPDLA-ALPRLIYLNLSNNLIRLPTGPPQDS 287
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
I G LS + ++ L+ LDLS+N++ P L L L++
Sbjct: 288 KGIHAPSEGWSALPLSAPSGNASGRPLSQ-LLNLDLSYNEIELIPDSFLEHLTSLCFLNL 346
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSP 464
S N L+T + L L + ++L N + A + T + + +R L ++
Sbjct: 347 SRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTF 406
Query: 465 LRLRGATFGSLSFEQLDPC 483
L +L ++ PC
Sbjct: 407 ANLASLQRLNLQGNRVSPC 425
Score = 68.9 bits (161), Expect = 4e-11
Identities = 82/312 (26%), Positives = 131/312 (41%), Gaps = 16/312 (5%)
Query: 109 LRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ---MSSETFRHLTSLKTLILANN 165
LR L+L+ N ++ + F+ L +L L L HN + +S+ L + +L L+ N
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGN 134
Query: 166 QI-STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
+ S L+ RL L L L++N LT L F+D+ L +L I +
Sbjct: 135 SLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFE 194
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PRL L+L N LT SL++L+ L L N + E + L
Sbjct: 195 GLPRLTHLNLSRN---SLTCISDFSLQQLRVLDLSCNSIEAF-QTASQPQAEFQLTWLDL 250
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDS--LKTINFSGNNLPLNEIA 342
++S+N I L T P DS + + + LPL+ +
Sbjct: 251 RENKLLHFPDLAALPRLIYLNLSNNLI---RLPT-GPPQDSKGIHAPSEGWSALPLSAPS 306
Query: 343 --IVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
+ L ++ + L+ ++ IP +F + L L+LS N L F + L L
Sbjct: 307 GNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLM 366
Query: 401 RLDISHNKLQTL 412
LD+SHN L+TL
Sbjct: 367 LLDLSHNALETL 378
Score = 41.9 bits (94), Expect = 0.006
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 12/196 (6%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P L L + + + I L +L LNL+ N L + A L L L L H
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL-NPE-- 197
N +E + R L SL+TL+L N + L F LA L L+L N ++ P+
Sbjct: 373 NALETLELGA-RALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEP 431
Query: 198 ------VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
F I LR + + + P L ELDL N + + L+
Sbjct: 432 GPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP-LTELDLSSNPGLEVATGALGGLE 490
Query: 252 -RLKKLKLDGNQLSVI 266
L+ L L GN L V+
Sbjct: 491 ASLEVLALQGNGLMVL 506
Score = 41.5 bits (93), Expect = 0.008
Identities = 68/299 (22%), Positives = 122/299 (40%), Gaps = 26/299 (8%)
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK---DIQHLRIFKCRRCL 214
+TL L+ NQ+ ++++ L LDLS N ++ L P F+ ++HL + R +
Sbjct: 52 ETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAM 111
Query: 215 LRRINTQIYHLVPRLEELDL-GENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
++ +PR+ LDL G +L+ L L L L N L+ + + F
Sbjct: 112 ATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRD 171
Query: 274 NRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK---IDRFHLQTFAPV------VD 324
L L L N ++S N I F LQ + ++
Sbjct: 172 MPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIE 231
Query: 325 SLKTIN-----FSGNNLPLNEIAIV----LQILPEIHGVGLANLSLQEIPQNFFTYNEHL 375
+ +T + F L L E ++ L LP + + L+N +L +P ++ +
Sbjct: 232 AFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSN-NLIRLPTGPPQDSKGI 290
Query: 376 VALDLSWNKLS-RFPFKLLSKTKFLQ--RLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
A W+ L P S Q LD+S+N+++ + + L+ L ++ +NL +N
Sbjct: 291 HAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRN 349
Score = 41.1 bits (92), Expect = 0.010
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 19/194 (9%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN---------FRGLINLT 134
+LR L + + + + ++F L +L+ LNL N ++ + F G+ +L
Sbjct: 387 SLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLR 446
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTD 193
L L N IE + + F H T L L L++N + L + A L +L L N L
Sbjct: 447 SLSLVDNEIELLRAGAFLH-TPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMV 505
Query: 194 LNPEV--FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L ++ F ++ L + + R L + LE LDL N F L L+
Sbjct: 506 LQVDLPCFICLKRLNLAENRLSHLPAWTQAV-----SLEVLDLRNNSFSLLPGSAMGGLE 560
Query: 252 -RLKKLKLDGNQLS 264
L++L L GN LS
Sbjct: 561 TSLRRLYLQGNPLS 574
Score = 37.9 bits (84), Expect = 0.094
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
+L L+L N+LT + FR + L +L L N + + F L L L L+ N +
Sbjct: 150 SLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSL 209
Query: 168 STLVSRLFRMLAKLSILDLSDNPL 191
T +S L +L +LDLS N +
Sbjct: 210 -TCISDF--SLQQLRVLDLSCNSI 230
Score = 32.3 bits (70), Expect = 4.7
Identities = 34/163 (20%), Positives = 61/163 (37%), Gaps = 4/163 (2%)
Query: 276 ELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNN 335
+ L LS N+ D+S N+I F + L+ ++ + N
Sbjct: 50 DTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTH-LEHLSLAHNR 108
Query: 336 LPLNEIAIV--LQILPEIHGVGLANLSLQE-IPQNFFTYNEHLVALDLSWNKLSRFPFKL 392
L + L LP + + L+ SL + + L L L+ N L+R
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 393 LSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L++LD+ N L + + + L + +NL +N+ C
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTC 211
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 73.7 bits (173), Expect = 2e-12
Identities = 74/337 (21%), Positives = 135/337 (40%), Gaps = 12/337 (3%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL NL LHL+ N + + F+ L L+ L L N+
Sbjct: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ KL+ LDLS+N + + + F+ I ++ + + I + +
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-----SVIVDNMFGRNRELHVLT 281
LE L L N + F + +++ L+L N L + + + R + T
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 240
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF---APVVDSLKTINFSGNNLPL 338
L H++ + + +P S ++ G L
Sbjct: 241 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGL-- 298
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
+ I + I + L S++ IP FT + L +D+S N++S K
Sbjct: 299 --MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKS 356
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L L + NK+ +++ L ++ + L N +C
Sbjct: 357 LTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393
Score = 69.3 bits (162), Expect = 3e-11
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 15 ICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGP 74
+CP++C C EG T V C + + IP + +V + + + L
Sbjct: 504 VCPEKCRC-------EG--TIVDCSNQKLVRIPSHLPE---YVTDLRLNDNEVSVLEATG 551
Query: 75 IFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
IF + NLR++++ N+ + + + +F G +++ L LT N L +V FRGL L
Sbjct: 552 IFKK---LPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLK 608
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L N I +S++TF L+S++ L L +N+I+T+ F L LS ++L NP
Sbjct: 609 TLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664
Score = 68.9 bits (161), Expect = 4e-11
Identities = 41/154 (26%), Positives = 74/154 (48%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+NLRVL+L N ++ + F+ L L L L+ N +
Sbjct: 62 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + F+ L L L+ NQI + + FR + + L L +N ++ + F+ ++
Sbjct: 122 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L I + RI ++ +P++ L L N
Sbjct: 182 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSN 215
Score = 66.1 bits (154), Expect = 3e-10
Identities = 37/103 (35%), Positives = 56/103 (54%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L NLR +NL++N + V F G ++ EL L N +E + FR L+ LKTL+L
Sbjct: 553 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 612
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N IS + + F L+ + +L L DN +T + P F + L
Sbjct: 613 RSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSL 655
Score = 62.5 bits (145), Expect = 4e-09
Identities = 34/120 (28%), Positives = 68/120 (56%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
E+ + +++ +I +F + L+ ++++ N ++ + D F+GL +LT L L N I ++
Sbjct: 311 EIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEI 370
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
+ F L SL+ L+L N+I+ L F+ L L++L L DN L ++ +F +Q ++
Sbjct: 371 AKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQ 430
Score = 62.5 bits (145), Expect = 4e-09
Identities = 71/363 (19%), Positives = 145/363 (39%), Gaps = 16/363 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
+ L N++ ++ A F L + + N I ++ + F+ L SL +L+L N+I+ +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
LF L L +L L+ N + L F+D+Q+L + L+ I+ ++ + ++
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 431
Query: 232 LDLGENLF----------KYLTSD--EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
L L +N F YL + E + +L ++S I F +
Sbjct: 432 LHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDY 491
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
+ + D S+ K+ R + + P + + + + N + +
Sbjct: 492 RSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVR--IPSHLP--EYVTDLRLNDNEVSVL 547
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
E + + LP + + L+N ++E+ + F + L L+ N+L ++ L
Sbjct: 548 EATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGL 607
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
+ L + N + +S L ++ ++L N A L+ ++T L S
Sbjct: 608 KTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNC 667
Query: 460 KCH 462
CH
Sbjct: 668 NCH 670
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP CTC+ V C+ + IP + + +V I + + G
Sbjct: 280 CPSPCTCSNNI---------VDCRGKGLMEIPANLPEG---IVEIRLEQNSIKAIPAGA- 326
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
FTQ + L+ + I + + I +F GL++L L L N +T + F GL++L
Sbjct: 327 FTQ---YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQL 383
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L+ N I + TF+ L +L L L +N++ T+ LF L + L L+ NP
Sbjct: 384 LLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNP 438
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/107 (29%), Positives = 51/107 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F L L+L+ N + + FRG+ ++ L LD+NHI
Sbjct: 111 LERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN IS ++ F + K+ L L N L
Sbjct: 171 CIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 52.0 bits (119), Expect = 5e-06
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F LK L+ L L+ NQ+SVI F ++L L L++
Sbjct: 59 IPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNK 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N+I + F + D +K + N++ E
Sbjct: 119 NKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITD-VKNLQLDNNHISCIEDG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ I F + + L L N L
Sbjct: 177 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 51.2 bits (117), Expect = 9e-06
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP++CTC T V C + +R +P M +DV + + N LT P
Sbjct: 725 CPEQCTCMETV---------VRCSNKGLRALPRG-MPKDVTELYLEG-----NHLTAVP- 768
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + +L + + N+++ + ++F + +L L L++N L + F GL +L
Sbjct: 769 -RELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRV 827
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + +F LTSL L L N +
Sbjct: 828 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 44.8 bits (101), Expect = 8e-04
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D+ N I R FA + +L+ ++ N + + E Q L ++ + L LQ +
Sbjct: 67 DLDRNNITRITKMDFAGL-KNLRVLHLEDNQVSVIERG-AFQDLKQLERLRLNKNKLQVL 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N + + + + L +
Sbjct: 125 PELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 185 ILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCH 222
Score = 41.1 bits (92), Expect = 0.010
Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 13/262 (4%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL--INLTELHLDHN 141
+++ L + N+++ I +F L++L +L L +NN++ ++ +F + I LH +H
Sbjct: 158 DVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Query: 142 HIE---QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL--SDNPLTDLNP 196
+ + S+ R ++ L + + + K + S+ P + N
Sbjct: 218 YCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANS 277
Query: 197 EVFKD--IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
I CR L I +L + E+ L +N K + + F K+LK
Sbjct: 278 ISCPSPCTCSNNIVDCRGKGLMEIPA---NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK 334
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
++ + NQ+S I + F + L L L N+ ++ NKI+
Sbjct: 335 RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCL 394
Query: 315 HLQTFAPVVDSLKTINFSGNNL 336
+ TF + +L ++ N L
Sbjct: 395 RVNTFQD-LQNLNLLSLYDNKL 415
Score = 41.1 bits (92), Expect = 0.010
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
L L + + L+N S+ + F+ HL L LS+N+L P + + L+ L +
Sbjct: 771 LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTL 830
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCS 439
N + ++ E L +++ + L N HCD CS
Sbjct: 831 HGNDISSVPEGSFNDLTSLSHLALGTNPLHCD-CS 864
Score = 39.9 bits (89), Expect = 0.023
Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
LK I+ S N + ++IA Q L + + L + EI + F L L L+ NK
Sbjct: 333 LKRIDISKNQI--SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANK 390
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NKLQT+S+ L++I ++L +N + CD C +
Sbjct: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCD-CHLKWLA 449
Query: 445 LYMTTTVLNSTIRVLKCHSPLRL 467
Y+ + ++ +C SP RL
Sbjct: 450 DYLQDNPIETS--GARCSSPRRL 470
Score = 35.1 bits (77), Expect = 0.66
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N + T V R L L+++DLS+N ++ L F ++ HL LR I
Sbjct: 757 LYLEGNHL-TAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++ + L L L N + F L L L L N L
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 32.7 bits (71), Expect = 3.5
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+DL N LT+ F ++ L L L N+L I + F R L VLTL N
Sbjct: 780 IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 833
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 73.7 bits (173), Expect = 2e-12
Identities = 74/337 (21%), Positives = 135/337 (40%), Gaps = 12/337 (3%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL NL LHL+ N + + F+ L L+ L L N+
Sbjct: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ KL+ LDLS+N + + + F+ I ++ + + I + +
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-----SVIVDNMFGRNRELHVLT 281
LE L L N + F + +++ L+L N L + + + R + T
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 240
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF---APVVDSLKTINFSGNNLPL 338
L H++ + + +P S ++ G L
Sbjct: 241 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGL-- 298
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
+ I + I + L S++ IP FT + L +D+S N++S K
Sbjct: 299 --MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKS 356
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L L + NK+ +++ L ++ + L N +C
Sbjct: 357 LTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393
Score = 68.9 bits (161), Expect = 4e-11
Identities = 41/154 (26%), Positives = 74/154 (48%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+NLRVL+L N ++ + F+ L L L L+ N +
Sbjct: 62 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + F+ L L L+ NQI + + FR + + L L +N ++ + F+ ++
Sbjct: 122 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L I + RI ++ +P++ L L N
Sbjct: 182 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSN 215
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 15 ICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGP 74
+CP++C C EG T V C + + IP + +V + + + L
Sbjct: 504 VCPEKCRC-------EG--TIVDCSNQKLVRIPSHLPE---YVTDLRLNDNEVSVLEATG 551
Query: 75 IFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
IF + NLR++++ N+ + + + +F G +++ L LT N L +V FRGL L
Sbjct: 552 IFKK---LPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLK 608
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L N I +S++TF L+S++ L L +N+I+T+ F L LS ++L NP
Sbjct: 609 TLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664
Score = 64.5 bits (150), Expect = 9e-10
Identities = 36/103 (34%), Positives = 55/103 (53%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L NLR +NL++N + V F G ++ EL L N +E + FR L+ LKTL+L
Sbjct: 553 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 612
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N I + + F L+ + +L L DN +T + P F + L
Sbjct: 613 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSL 655
Score = 62.5 bits (145), Expect = 4e-09
Identities = 34/120 (28%), Positives = 68/120 (56%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
E+ + +++ +I +F + L+ ++++ N ++ + D F+GL +LT L L N I ++
Sbjct: 311 EIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEI 370
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
+ F L SL+ L+L N+I+ L F+ L L++L L DN L ++ +F +Q ++
Sbjct: 371 AKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQ 430
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/363 (19%), Positives = 145/363 (39%), Gaps = 16/363 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
+ L N++ ++ A F L + + N I ++ + F+ L SL +L+L N+I+ +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
LF L L +L L+ N + L F+D+Q+L + L+ I+ ++ + ++
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 431
Query: 232 LDLGENLF----------KYLTSD--EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
L L +N F YL + E + +L ++S I F +
Sbjct: 432 LHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDY 491
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
+ + D S+ K+ R + + P + + + + N + +
Sbjct: 492 RSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVR--IPSHLP--EYVTDLRLNDNEVSVL 547
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
E + + LP + + L+N ++E+ + F + L L+ N+L ++ L
Sbjct: 548 EATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGL 607
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
+ L + N + +S L ++ ++L N A L+ ++T L S
Sbjct: 608 KTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNC 667
Query: 460 KCH 462
CH
Sbjct: 668 NCH 670
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP CTC+ V C+ + IP + + +V I + + G
Sbjct: 280 CPSPCTCSNNI---------VDCRGKGLMEIPANLPEG---IVEIRLEQNSIKAIPAGA- 326
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
FTQ + L+ + I + + I +F GL++L L L N +T + F GL++L
Sbjct: 327 FTQ---YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQL 383
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L+ N I + TF+ L +L L L +N++ T+ LF L + L L+ NP
Sbjct: 384 LLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNP 438
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/107 (29%), Positives = 51/107 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F L L+L+ N + + FRG+ ++ L LD+NHI
Sbjct: 111 LERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN IS ++ F + K+ L L N L
Sbjct: 171 CIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 52.0 bits (119), Expect = 5e-06
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F LK L+ L L+ NQ+SVI F ++L L L++
Sbjct: 59 IPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNK 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N+I + F + D +K + N++ E
Sbjct: 119 NKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITD-VKNLQLDNNHISCIEDG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ I F + + L L N L
Sbjct: 177 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 51.2 bits (117), Expect = 9e-06
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP++CTC T V C + +R +P M +DV + + N LT P
Sbjct: 725 CPEQCTCMETV---------VRCSNKGLRALPRG-MPKDVTELYLEG-----NHLTAVP- 768
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + +L + + N+++ + ++F + +L L L++N L + F GL +L
Sbjct: 769 -RELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRV 827
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + +F LTSL L L N +
Sbjct: 828 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 44.8 bits (101), Expect = 8e-04
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D+ N I R FA + +L+ ++ N + + E Q L ++ + L LQ +
Sbjct: 67 DLDRNNITRITKMDFAGL-KNLRVLHLEDNQVSVIERG-AFQDLKQLERLRLNKNKLQVL 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N + + + + L +
Sbjct: 125 PELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 185 ILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCH 222
Score = 41.1 bits (92), Expect = 0.010
Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 13/262 (4%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL--INLTELHLDHN 141
+++ L + N+++ I +F L++L +L L +NN++ ++ +F + I LH +H
Sbjct: 158 DVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Query: 142 HIE---QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL--SDNPLTDLNP 196
+ + S+ R ++ L + + + K + S+ P + N
Sbjct: 218 YCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANS 277
Query: 197 EVFKD--IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
I CR L I +L + E+ L +N K + + F K+LK
Sbjct: 278 ISCPSPCTCSNNIVDCRGKGLMEIPA---NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK 334
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
++ + NQ+S I + F + L L L N+ ++ NKI+
Sbjct: 335 RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCL 394
Query: 315 HLQTFAPVVDSLKTINFSGNNL 336
+ TF + +L ++ N L
Sbjct: 395 RVNTFQD-LQNLNLLSLYDNKL 415
Score = 41.1 bits (92), Expect = 0.010
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
L L + + L+N S+ + F+ HL L LS+N+L P + + L+ L +
Sbjct: 771 LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTL 830
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCS 439
N + ++ E L +++ + L N HCD CS
Sbjct: 831 HGNDISSVPEGSFNDLTSLSHLALGTNPLHCD-CS 864
Score = 39.9 bits (89), Expect = 0.023
Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
LK I+ S N + ++IA Q L + + L + EI + F L L L+ NK
Sbjct: 333 LKRIDISKNQI--SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANK 390
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NKLQT+S+ L++I ++L +N + CD C +
Sbjct: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCD-CHLKWLA 449
Query: 445 LYMTTTVLNSTIRVLKCHSPLRL 467
Y+ + ++ +C SP RL
Sbjct: 450 DYLQDNPIETS--GARCSSPRRL 470
Score = 35.1 bits (77), Expect = 0.66
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N + T V R L L+++DLS+N ++ L F ++ HL LR I
Sbjct: 757 LYLEGNHL-TAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++ + L L L N + F L L L L N L
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 32.7 bits (71), Expect = 3.5
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+DL N LT+ F ++ L L L N+L I + F R L VLTL N
Sbjct: 780 IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 833
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 73.7 bits (173), Expect = 2e-12
Identities = 74/337 (21%), Positives = 135/337 (40%), Gaps = 12/337 (3%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL NL LHL+ N + + F+ L L+ L L N+
Sbjct: 97 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 156
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ KL+ LDLS+N + + + F+ I ++ + + I + +
Sbjct: 157 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 216
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-----SVIVDNMFGRNRELHVLT 281
LE L L N + F + +++ L+L N L + + + R + T
Sbjct: 217 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 276
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTF---APVVDSLKTINFSGNNLPL 338
L H++ + + +P S ++ G L
Sbjct: 277 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGL-- 334
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
+ I + I + L S++ IP FT + L +D+S N++S K
Sbjct: 335 --MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKS 392
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L L + NK+ +++ L ++ + L N +C
Sbjct: 393 LTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 429
Score = 68.9 bits (161), Expect = 4e-11
Identities = 41/154 (26%), Positives = 74/154 (48%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+NLRVL+L N ++ + F+ L L L L+ N +
Sbjct: 98 NAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 157
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + F+ L L L+ NQI + + FR + + L L +N ++ + F+ ++
Sbjct: 158 QVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 217
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L I + RI ++ +P++ L L N
Sbjct: 218 DLEILTLNNNNISRILVTSFNHMPKIRTLRLHSN 251
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 15 ICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGP 74
+CP++C C EG T V C + + IP + +V + + + L
Sbjct: 540 VCPEKCRC-------EG--TIVDCSNQKLVRIPSHLPE---YVTDLRLNDNEVSVLEATG 587
Query: 75 IFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLT 134
IF + NLR++++ N+ + + + +F G +++ L LT N L +V FRGL L
Sbjct: 588 IFKK---LPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLK 644
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L N I +S++TF L+S++ L L +N+I+T+ F L LS ++L NP
Sbjct: 645 TLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 700
Score = 64.5 bits (150), Expect = 9e-10
Identities = 36/103 (34%), Positives = 55/103 (53%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L NLR +NL++N + V F G ++ EL L N +E + FR L+ LKTL+L
Sbjct: 589 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 648
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N I + + F L+ + +L L DN +T + P F + L
Sbjct: 649 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSL 691
Score = 62.5 bits (145), Expect = 4e-09
Identities = 34/120 (28%), Positives = 68/120 (56%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
E+ + +++ +I +F + L+ ++++ N ++ + D F+GL +LT L L N I ++
Sbjct: 347 EIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEI 406
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
+ F L SL+ L+L N+I+ L F+ L L++L L DN L ++ +F +Q ++
Sbjct: 407 AKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQ 466
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/363 (19%), Positives = 145/363 (39%), Gaps = 16/363 (4%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
+ L N++ ++ A F L + + N I ++ + F+ L SL +L+L N+I+ +
Sbjct: 348 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 407
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
LF L L +L L+ N + L F+D+Q+L + L+ I+ ++ + ++
Sbjct: 408 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 467
Query: 232 LDLGENLF----------KYLTSD--EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
L L +N F YL + E + +L ++S I F +
Sbjct: 468 LHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDY 527
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLN 339
+ + D S+ K+ R + + P + + + + N + +
Sbjct: 528 RSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVR--IPSHLP--EYVTDLRLNDNEVSVL 583
Query: 340 EIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFL 399
E + + LP + + L+N ++E+ + F + L L+ N+L ++ L
Sbjct: 584 EATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGL 643
Query: 400 QRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVL 459
+ L + N + +S L ++ ++L N A L+ ++T L S
Sbjct: 644 KTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNC 703
Query: 460 KCH 462
CH
Sbjct: 704 NCH 706
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP CTC+ V C+ + IP + + +V I + + G
Sbjct: 316 CPSPCTCSNNI---------VDCRGKGLMEIPANLPEG---IVEIRLEQNSIKAIPAGA- 362
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
FTQ + L+ + I + + I +F GL++L L L N +T + F GL++L
Sbjct: 363 FTQ---YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQL 419
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L+ N I + TF+ L +L L L +N++ T+ LF L + L L+ NP
Sbjct: 420 LLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNP 474
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/107 (29%), Positives = 51/107 (47%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F L L+L+ N + + FRG+ ++ L LD+NHI
Sbjct: 147 LERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHIS 206
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN IS ++ F + K+ L L N L
Sbjct: 207 CIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 52.0 bits (119), Expect = 5e-06
Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F LK L+ L L+ NQ+SVI F ++L L L++
Sbjct: 95 IPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNK 154
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N+I + F + D +K + N++ E
Sbjct: 155 NKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITD-VKNLQLDNNHISCIEDG-A 212
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ I F + + L L N L
Sbjct: 213 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 51.2 bits (117), Expect = 9e-06
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP++CTC T V C + +R +P M +DV + + N LT P
Sbjct: 761 CPEQCTCMETV---------VRCSNKGLRALPRG-MPKDVTELYLEG-----NHLTAVP- 804
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + +L + + N+++ + ++F + +L L L++N L + F GL +L
Sbjct: 805 -RELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRV 863
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + +F LTSL L L N +
Sbjct: 864 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 895
Score = 44.8 bits (101), Expect = 8e-04
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D+ N I R FA + +L+ ++ N + + E Q L ++ + L LQ +
Sbjct: 103 DLDRNNITRITKMDFAGL-KNLRVLHLEDNQVSVIERG-AFQDLKQLERLRLNKNKLQVL 160
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N + + + + L +
Sbjct: 161 PELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLE 220
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 221 ILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCH 258
Score = 41.1 bits (92), Expect = 0.010
Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 13/262 (4%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGL--INLTELHLDHN 141
+++ L + N+++ I +F L++L +L L +NN++ ++ +F + I LH +H
Sbjct: 194 DVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Query: 142 HIE---QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDL--SDNPLTDLNP 196
+ + S+ R ++ L + + + K + S+ P + N
Sbjct: 254 YCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANS 313
Query: 197 EVFKD--IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
I CR L I +L + E+ L +N K + + F K+LK
Sbjct: 314 ISCPSPCTCSNNIVDCRGKGLMEIPA---NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK 370
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
++ + NQ+S I + F + L L L N+ ++ NKI+
Sbjct: 371 RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCL 430
Query: 315 HLQTFAPVVDSLKTINFSGNNL 336
+ TF + +L ++ N L
Sbjct: 431 RVNTFQD-LQNLNLLSLYDNKL 451
Score = 41.1 bits (92), Expect = 0.010
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
L L + + L+N S+ + F+ HL L LS+N+L P + + L+ L +
Sbjct: 807 LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTL 866
Query: 405 SHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCS 439
N + ++ E L +++ + L N HCD CS
Sbjct: 867 HGNDISSVPEGSFNDLTSLSHLALGTNPLHCD-CS 900
Score = 39.9 bits (89), Expect = 0.023
Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
LK I+ S N + ++IA Q L + + L + EI + F L L L+ NK
Sbjct: 369 LKRIDISKNQI--SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANK 426
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NKLQT+S+ L++I ++L +N + CD C +
Sbjct: 427 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCD-CHLKWLA 485
Query: 445 LYMTTTVLNSTIRVLKCHSPLRL 467
Y+ + ++ +C SP RL
Sbjct: 486 DYLQDNPIETS--GARCSSPRRL 506
Score = 35.1 bits (77), Expect = 0.66
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N + T V R L L+++DLS+N ++ L F ++ HL LR I
Sbjct: 793 LYLEGNHL-TAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 851
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
++ + L L L N + F L L L L N L
Sbjct: 852 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 895
Score = 32.7 bits (71), Expect = 3.5
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 232 LDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+DL N LT+ F ++ L L L N+L I + F R L VLTL N
Sbjct: 816 IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 869
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETFRHLTSLKTLILANNQ 166
NL L L NNL+++ FR L L EL L D+ H+ + +TF+ L L++L L Q
Sbjct: 83 NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQ 142
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+S+L +FR L L L L +N L L ++F D+ +L LR + ++ +
Sbjct: 143 LSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGL 202
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L N + + F L RL L L N L+ + L L L+ N
Sbjct: 203 GSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/152 (34%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
L L +N I + TF ++L TL L +N +ST+ FR L L LDL DN L L
Sbjct: 65 LFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
P+ F+ ++ L+ RC L + I+ + L+ L L EN +L D F L L
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN+L ++ +++F L L L NR
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Score = 69.7 bits (163), Expect = 3e-11
Identities = 66/208 (31%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Query: 58 VIIAAPPDRPN-FLTIGPIFT-QPAPF-VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNL 114
V ++ PP FL I T +P F NL L + ++N+ +I +F LQ L L+L
Sbjct: 54 VPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDL 113
Query: 115 THN-NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
N +L S+ D F+GL L LHL + + FR L SL+ L L N + L
Sbjct: 114 GDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDD 173
Query: 174 LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELD 233
LF LA LS L L N L L VF+ + L L+ ++ + + RL L
Sbjct: 174 LFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILY 233
Query: 234 LGENLFKYLTSDEFISLKRLKKLKLDGN 261
L N L + L L+ L+L+ N
Sbjct: 234 LFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 52/108 (48%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L+ L++ +++ + F L NL L L N L + FRGL +L L L N
Sbjct: 155 VSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
++ + FR L+ L L L NN +++L L L L L+ NP
Sbjct: 215 LQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANP 262
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETFRHLTSLKTLILANNQ 166
NL L L NNL+++ FR L L EL L D+ H+ + +TF+ L L++L L Q
Sbjct: 83 NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQ 142
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+S+L +FR L L L L +N L L ++F D+ +L LR + ++ +
Sbjct: 143 LSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGL 202
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L N + + F L RL L L N L+ + L L L+ N
Sbjct: 203 GSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/152 (34%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
L L +N I + TF ++L TL L +N +ST+ FR L L LDL DN L L
Sbjct: 65 LFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
P+ F+ ++ L+ RC L + I+ + L+ L L EN +L D F L L
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN+L ++ +++F L L L NR
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Score = 69.7 bits (163), Expect = 3e-11
Identities = 66/208 (31%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Query: 58 VIIAAPPDRPN-FLTIGPIFT-QPAPF-VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNL 114
V ++ PP FL I T +P F NL L + ++N+ +I +F LQ L L+L
Sbjct: 54 VPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDL 113
Query: 115 THN-NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
N +L S+ D F+GL L LHL + + FR L SL+ L L N + L
Sbjct: 114 GDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDD 173
Query: 174 LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELD 233
LF LA LS L L N L L VF+ + L L+ ++ + + RL L
Sbjct: 174 LFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILY 233
Query: 234 LGENLFKYLTSDEFISLKRLKKLKLDGN 261
L N L + L L+ L+L+ N
Sbjct: 234 LFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 52/108 (48%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L+ L++ +++ + F L NL L L N L + FRGL +L L L N
Sbjct: 155 VSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
++ + FR L+ L L L NN +++L L L L L+ NP
Sbjct: 215 LQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANP 262
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/152 (34%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
L L +N I + TF ++L TL L +N +ST+ FR L L LDL DN L L
Sbjct: 65 LFLQNNLIRTLRPSTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
P+ F+ ++ L+ RC L + I+ + L+ L L EN +L D F L L
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN+L ++ +++F L L L NR
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETFRHLTSLKTLILANNQ 166
NL L L NNL+++ FR L L EL L D+ H+ + +TF+ L L++L L Q
Sbjct: 83 NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQ 142
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+S+L +FR L L L L +N L L ++F D+ +L LR + ++ +
Sbjct: 143 LSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGL 202
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L N + + F L RL L L N L+ + L L L+ N
Sbjct: 203 GSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 70.1 bits (164), Expect = 2e-11
Identities = 66/208 (31%), Positives = 95/208 (45%), Gaps = 4/208 (1%)
Query: 58 VIIAAPPDRPN-FLTIGPIFT-QPAPF-VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNL 114
V ++ PP FL I T +P+ F NL L + ++N+ +I +F LQ L L+L
Sbjct: 54 VPLSLPPSTQRLFLQNNLIRTLRPSTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDL 113
Query: 115 THN-NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
N +L S+ D F+GL L LHL + + FR L SL+ L L N + L
Sbjct: 114 GDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDD 173
Query: 174 LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELD 233
LF LA LS L L N L L VF+ + L L+ ++ + + RL L
Sbjct: 174 LFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILY 233
Query: 234 LGENLFKYLTSDEFISLKRLKKLKLDGN 261
L N L + L L+ L+L+ N
Sbjct: 234 LFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 52/108 (48%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L+ L++ +++ + F L NL L L N L + FRGL +L L L N
Sbjct: 155 VSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
++ + FR L+ L L L NN +++L L L L L+ NP
Sbjct: 215 LQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANP 262
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETFRHLTSLKTLILANNQ 166
NL L L NNL+++ FR L L EL L D+ H+ + +TF+ L L++L L Q
Sbjct: 83 NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQ 142
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+S+L +FR L L L L +N L L ++F D+ +L LR + ++ +
Sbjct: 143 LSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGL 202
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L N + + F L RL L L N L+ + L L L+ N
Sbjct: 203 GSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/152 (34%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
L L +N I + TF ++L TL L +N +ST+ FR L L LDL DN L L
Sbjct: 65 LFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
P+ F+ ++ L+ RC L + I+ + L+ L L EN +L D F L L
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN+L ++ +++F L L L NR
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Score = 69.7 bits (163), Expect = 3e-11
Identities = 66/208 (31%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Query: 58 VIIAAPPDRPN-FLTIGPIFT-QPAPF-VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNL 114
V ++ PP FL I T +P F NL L + ++N+ +I +F LQ L L+L
Sbjct: 54 VPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDL 113
Query: 115 THN-NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
N +L S+ D F+GL L LHL + + FR L SL+ L L N + L
Sbjct: 114 GDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDD 173
Query: 174 LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELD 233
LF LA LS L L N L L VF+ + L L+ ++ + + RL L
Sbjct: 174 LFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILY 233
Query: 234 LGENLFKYLTSDEFISLKRLKKLKLDGN 261
L N L + L L+ L+L+ N
Sbjct: 234 LFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 52/108 (48%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V+L+ L++ +++ + F L NL L L N L + FRGL +L L L N
Sbjct: 155 VSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR 214
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
++ + FR L+ L L L NN +++L L L L L+ NP
Sbjct: 215 LQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANP 262
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 72.9 bits (171), Expect = 3e-12
Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 8/147 (5%)
Query: 53 RDVHVVIIAAPPDRPNFLTIGPIFT-----QPAPFVNLRELHIV---NSNVPSIGQFSFW 104
R +H+++ A P P + F QP F LR L+ + N+ + I +F
Sbjct: 65 RCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFE 124
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L+NL+ L L N + S+ F+GL +L +L+L N IE + ++F+HL L+ L L N
Sbjct: 125 DLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHN 184
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPL 191
N+I+ LV F L + L L N L
Sbjct: 185 NRITHLVPGTFNHLESMKRLRLDSNTL 211
Score = 66.9 bits (156), Expect = 2e-10
Identities = 40/128 (31%), Positives = 61/128 (47%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L N I ++ FR L +L TL+L NNQI + S F L L L L N + ++
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+ FK + L + ++ + +P+LE L L N +L F L+ +K+
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 256 LKLDGNQL 263
L+LD N L
Sbjct: 204 LRLDSNTL 211
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + FR L NL L L++N I+++ S F L +LK L L N+I ++
Sbjct: 83 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 142
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
+ F+ LA L L L N + L+P+ F QHL K R L N +I HLVP
Sbjct: 143 DRQAFKGLASLEQLYLHFNQIETLDPDSF---QHLP--KLERLFLH--NNRITHLVP 192
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/126 (26%), Positives = 62/126 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N+I + FR L L+ L L++N + + F+D+++L+ + ++ I+
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
Q + + LE+L L N + L D F L +L++L L N+++ +V F +
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 280 LTLSRN 285
L L N
Sbjct: 204 LRLDSN 209
Score = 41.5 bits (93), Expect = 0.008
Identities = 28/105 (26%), Positives = 50/105 (47%)
Query: 182 SILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY 241
SILDL N + ++ P F+ +++L ++RI + + + L+ L L +N +
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 242 LTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ F L L++L L NQ+ + + F +L L L NR
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNR 186
Score = 35.1 bits (77), Expect = 0.66
Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+Q I + F L L L +N++ L+RL + +N++ L L
Sbjct: 139 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 198
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK-CHSPLRLRGATFGSLSFEQ 479
E++ + L N HCD C + + T + + C P R++G + +++ E+
Sbjct: 199 ESMKRLRLDSNTLHCD-CEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEE 257
Query: 480 LD 481
L+
Sbjct: 258 LN 259
>BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 11/266 (4%)
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLT 281
+L + L L EN + ++ L +L++L LD N +S + D F L +L
Sbjct: 106 NLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLF 165
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS+N + N+I F + SL+ + GN L I
Sbjct: 166 LSKNHLSSVPVGLPVDLQELR---VDENRIAVISDMAFQNLT-SLERLIVDGNLLTNKGI 221
Query: 342 AI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A L ++ + SL P + HL+ L L N+++ P S + L+
Sbjct: 222 AEGTFSHLTKLKEFSIVRNSLSHPPPDL--PGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK 460
RLDIS+N+L+ L++ L + ++ N W CD CS + ++ + +R
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD-CSIKWVTEWLKYIPSSLNVRGFM 338
Query: 461 CHSPLRLRGATFGSLSFEQLDPCPTT 486
C P ++RG L+ L CPTT
Sbjct: 339 CQGPEQVRGMAVRELNMNLLS-CPTT 363
Score = 62.5 bits (145), Expect = 4e-09
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
PA N++ +H V + +F +N+RVL+L NN+ ++ L+ L ELHL
Sbjct: 81 PAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHL 140
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N I + E FR SLK L L+ N +S++ L L L + +N + ++
Sbjct: 141 DDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL---PVDLQELRVDENRIAVISD 197
Query: 197 EVFKDIQHL-RIFKCRRCLLRR-INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
F+++ L R+ L + I + + +L+E + N + D + L
Sbjct: 198 MAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD--LPGTHLI 255
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L NQ++ I F R+L L +S N+
Sbjct: 256 RLYLQDNQINHIPLTAFSNLRKLERLDISNNQ 287
Score = 47.2 bits (107), Expect = 2e-04
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDH 140
V+L+EL + + + I +F L +L L + N LT+ + F L L E +
Sbjct: 180 VDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVR 239
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + + T L L L +NQI+ + F L KL LD+S+N L L VF
Sbjct: 240 NSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFD 297
Query: 201 DIQHLRIFKCR 211
++ +L+ R
Sbjct: 298 NLSNLKQLTAR 308
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 82 FVNLRELH--IVNSNV---PSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
F NL L IV+ N+ I + +F L L+ ++ N+L+ D G +L L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD-LPGT-HLIRL 257
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L N I + F +L L+ L ++NNQ+ L +F L+ L L +NP
Sbjct: 258 YLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNP 311
>BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 11/266 (4%)
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLT 281
+L + L L EN + ++ L +L++L LD N +S + D F L +L
Sbjct: 106 NLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLF 165
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS+N + N+I F + SL+ + GN L I
Sbjct: 166 LSKNHLSSVPVGLPVDLQELR---VDENRIAVISDMAFQNLT-SLERLIVDGNLLTNKGI 221
Query: 342 AI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A L ++ + SL P + HL+ L L N+++ P S + L+
Sbjct: 222 AEGTFSHLTKLKEFSIVRNSLSHPPPDL--PGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK 460
RLDIS+N+L+ L++ L + ++ N W CD CS + ++ + +R
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD-CSIKWVTEWLKYIPSSLNVRGFM 338
Query: 461 CHSPLRLRGATFGSLSFEQLDPCPTT 486
C P ++RG L+ L CPTT
Sbjct: 339 CQGPEQVRGMAVRELNMNLLS-CPTT 363
Score = 62.5 bits (145), Expect = 4e-09
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
PA N++ +H V + +F +N+RVL+L NN+ ++ L+ L ELHL
Sbjct: 81 PAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHL 140
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N I + E FR SLK L L+ N +S++ L L L + +N + ++
Sbjct: 141 DDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL---PVDLQELRVDENRIAVISD 197
Query: 197 EVFKDIQHL-RIFKCRRCLLRR-INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
F+++ L R+ L + I + + +L+E + N + D + L
Sbjct: 198 MAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD--LPGTHLI 255
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L NQ++ I F R+L L +S N+
Sbjct: 256 RLYLQDNQINHIPLTAFSNLRKLERLDISNNQ 287
Score = 47.2 bits (107), Expect = 2e-04
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDH 140
V+L+EL + + + I +F L +L L + N LT+ + F L L E +
Sbjct: 180 VDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVR 239
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + + T L L L +NQI+ + F L KL LD+S+N L L VF
Sbjct: 240 NSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFD 297
Query: 201 DIQHLRIFKCR 211
++ +L+ R
Sbjct: 298 NLSNLKQLTAR 308
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 82 FVNLRELH--IVNSNV---PSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
F NL L IV+ N+ I + +F L L+ ++ N+L+ D G +L L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD-LPGT-HLIRL 257
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L N I + F +L L+ L ++NNQ+ L +F L+ L L +NP
Sbjct: 258 YLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNP 311
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 72.9 bits (171), Expect = 3e-12
Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 8/147 (5%)
Query: 53 RDVHVVIIAAPPDRPNFLTIGPIFT-----QPAPFVNLRELHIV---NSNVPSIGQFSFW 104
R +H+++ A P P + F QP F LR L+ + N+ + I +F
Sbjct: 43 RCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFE 102
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L+NL+ L L N + S+ F+GL +L +L+L N IE + ++F+HL L+ L L N
Sbjct: 103 DLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHN 162
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPL 191
N+I+ LV F L + L L N L
Sbjct: 163 NRITHLVPGTFNHLESMKRLRLDSNTL 189
Score = 66.9 bits (156), Expect = 2e-10
Identities = 40/128 (31%), Positives = 61/128 (47%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L N I ++ FR L +L TL+L NNQI + S F L L L L N + ++
Sbjct: 62 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 121
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+ FK + L + ++ + +P+LE L L N +L F L+ +K+
Sbjct: 122 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 181
Query: 256 LKLDGNQL 263
L+LD N L
Sbjct: 182 LRLDSNTL 189
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + FR L NL L L++N I+++ S F L +LK L L N+I ++
Sbjct: 61 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 120
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
+ F+ LA L L L N + L+P+ F QHL K R L N +I HLVP
Sbjct: 121 DRQAFKGLASLEQLYLHFNQIETLDPDSF---QHLP--KLERLFLH--NNRITHLVP 170
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/126 (26%), Positives = 62/126 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N+I + FR L L+ L L++N + + F+D+++L+ + ++ I+
Sbjct: 62 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 121
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
Q + + LE+L L N + L D F L +L++L L N+++ +V F +
Sbjct: 122 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 181
Query: 280 LTLSRN 285
L L N
Sbjct: 182 LRLDSN 187
Score = 41.5 bits (93), Expect = 0.008
Identities = 28/105 (26%), Positives = 50/105 (47%)
Query: 182 SILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY 241
SILDL N + ++ P F+ +++L ++RI + + + L+ L L +N +
Sbjct: 60 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 119
Query: 242 LTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ F L L++L L NQ+ + + F +L L L NR
Sbjct: 120 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNR 164
Score = 35.1 bits (77), Expect = 0.66
Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+Q I + F L L L +N++ L+RL + +N++ L L
Sbjct: 117 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 176
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK-CHSPLRLRGATFGSLSFEQ 479
E++ + L N HCD C + + T + + C P R++G + +++ E+
Sbjct: 177 ESMKRLRLDSNTLHCD-CEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEE 235
Query: 480 LD 481
L+
Sbjct: 236 LN 237
>AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein.
Length = 660
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 11/266 (4%)
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLT 281
+L + L L EN + ++ L +L++L LD N +S + D F L +L
Sbjct: 106 NLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLF 165
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS+N + N+I F + SL+ + GN L I
Sbjct: 166 LSKNHLSSVPVGLPVDLQELR---VDENRIAVISDMAFQNLT-SLERLIVDGNLLTNKGI 221
Query: 342 AI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A L ++ + SL P + HL+ L L N+++ P S + L+
Sbjct: 222 AEGTFSHLTKLKEFSIVRNSLSHPPPDL--PGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK 460
RLDIS+N+L+ L++ L + ++ N W CD CS + ++ + +R
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD-CSIKWVTEWLKYIPSSLNVRGFM 338
Query: 461 CHSPLRLRGATFGSLSFEQLDPCPTT 486
C P ++RG L+ L CPTT
Sbjct: 339 CQGPEQVRGMAVRELNMNLLS-CPTT 363
Score = 62.5 bits (145), Expect = 4e-09
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
PA N++ +H V + +F +N+RVL+L NN+ ++ L+ L ELHL
Sbjct: 81 PAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHL 140
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N I + E FR SLK L L+ N +S++ L L L + +N + ++
Sbjct: 141 DDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL---PVDLQELRVDENRIAVISD 197
Query: 197 EVFKDIQHL-RIFKCRRCLLRR-INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
F+++ L R+ L + I + + +L+E + N + D + L
Sbjct: 198 MAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD--LPGTHLI 255
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L NQ++ I F R+L L +S N+
Sbjct: 256 RLYLQDNQINHIPLTAFSNLRKLERLDISNNQ 287
Score = 47.2 bits (107), Expect = 2e-04
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDH 140
V+L+EL + + + I +F L +L L + N LT+ + F L L E +
Sbjct: 180 VDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVR 239
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + + T L L L +NQI+ + F L KL LD+S+N L L VF
Sbjct: 240 NSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFD 297
Query: 201 DIQHLRIFKCR 211
++ +L+ R
Sbjct: 298 NLSNLKQLTAR 308
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 82 FVNLRELH--IVNSNV---PSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
F NL L IV+ N+ I + +F L L+ ++ N+L+ D G +L L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD-LPGT-HLIRL 257
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L N I + F +L L+ L ++NNQ+ L +F L+ L L +NP
Sbjct: 258 YLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNP 311
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 540 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 599
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 600 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 656
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 559 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 618
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 619 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 665
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 169 LTLNNN 174
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 94 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 154 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + I +F GL++L L L N +T + F GL L L L+ N I + + F
Sbjct: 335 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 394
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 395 QDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 439
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/102 (26%), Positives = 55/102 (53%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L +N I +++ + F+ L SL +L+L N+I+ L +F L L +L L+ N + + P+
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
F+D+Q+L + ++ + + + ++ L L +N F
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 50 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 107
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 108 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 167
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 168 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 205
Score = 48.4 bits (110), Expect = 7e-05
Identities = 28/94 (29%), Positives = 49/94 (52%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L++N + + D F+GL +L L L N I + F L +L+ L+L N+I+ +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
F+ L LS+L L DN + L F ++ ++
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQ 425
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 533 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 592
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 593 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 652
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 653 LQSLSTLNLLANPF 666
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 42 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 101
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 102 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 159
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 160 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 534 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 593
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 594 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 653
Query: 275 RELHVLTLSRN 285
+ L L L N
Sbjct: 654 QSLSTLNLLAN 664
Score = 42.7 bits (96), Expect = 0.003
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 10/139 (7%)
Query: 133 LTELHLDHNHIEQMSSETF---RHLTSLKTLI-------LANNQISTLVSRLFRMLAKLS 182
+TE+ L+ N I+ + F R L ++ L L+NNQI+ + F+ L L+
Sbjct: 294 MTEIRLELNGIKSIPPGAFSPYRKLRRIRPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLN 353
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
L L N +TDL VF + L++ + I + + L L L +N + L
Sbjct: 354 SLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSL 413
Query: 243 TSDEFISLKRLKKLKLDGN 261
F SL+ ++ L L N
Sbjct: 414 AKGTFTSLRAIQTLHLAQN 432
Score = 39.5 bits (88), Expect = 0.031
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 4/143 (2%)
Query: 334 NNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKL 392
+N + EIA Q L ++ + L + ++P+ F L L L+ NK++
Sbjct: 334 SNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDA 393
Query: 393 LSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVL 452
+ L L + NK+Q+L++ L AI ++L +N + CD C+ + ++ T +
Sbjct: 394 FQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLADFLRTNPI 452
Query: 453 NSTIRVLKCHSPLRLRGATFGSL 475
++ +C SP RL G +
Sbjct: 453 ETS--GARCASPRRLANKRIGQI 473
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 141 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 35.5 bits (78), Expect = 0.50
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 184 LDLSDNPLTDLNPE-VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
L L++N ++ L +FK + HL+ + I + + EL L N + +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
S F L L+ L L N++S I ++ F R + +L+L N+
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 641
Score = 33.1 bits (72), Expect = 2.7
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 432
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 540 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 598
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 599 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 658
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 659 LNLLANPFNCN 669
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 663
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 330 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 389
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 390 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 186 LTLNNN 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 205 LR 206
++
Sbjct: 431 IQ 432
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 429 RAIQTLHLAQNPF 441
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 431 IQTLHLAQN 439
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 111 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 171 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 819
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 660
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 661 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 721 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 775
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 776 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 67 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 125 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 185 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 222
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 660 LQSLSTLNLLANPF 673
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 734 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 777
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 778 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 836
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 818
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 819 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 177 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 335 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 451
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 452 DFLRTNPIETS--GARCASPRRLANKRIGQI 480
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 158 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 334 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 393
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 394 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 439
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 849 EGIFADVTSLSHLAIGANPLYCD 871
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 605
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 606 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 665
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 666 LNLLANPFNCN 676
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 663
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 330 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 389
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 390 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 186 LTLNNN 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 205 LR 206
++
Sbjct: 431 IQ 432
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 429 RAIQTLHLAQNPF 441
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 431 IQTLHLAQN 439
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 111 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 171 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 819
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 660
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 661 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 721 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 775
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 776 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 67 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 125 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 185 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 222
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 660 LQSLSTLNLLANPF 673
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 734 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 777
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 778 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 836
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 818
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 819 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 177 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 335 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 451
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 452 DFLRTNPIETS--GARCASPRRLANKRIGQI 480
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 158 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 334 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 393
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 394 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 439
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 849 EGIFADVTSLSHLAIGANPLYCD 871
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 605
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 606 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 665
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 666 LNLLANPFNCN 676
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 540 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 599
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 600 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 656
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 559 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 618
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 619 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 665
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 169 LTLNNN 174
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 94 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 153
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 154 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + I +F GL++L L L N +T + F GL L L L+ N I + + F
Sbjct: 335 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 394
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 395 QDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 439
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/102 (26%), Positives = 55/102 (53%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L +N I +++ + F+ L SL +L+L N+I+ L +F L L +L L+ N + + P+
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
F+D+Q+L + ++ + + + ++ L L +N F
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 50 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 107
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 108 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 167
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 168 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 205
Score = 48.4 bits (110), Expect = 7e-05
Identities = 28/94 (29%), Positives = 49/94 (52%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L++N + + D F+GL +L L L N I + F L +L+ L+L N+I+ +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLR 206
F+ L LS+L L DN + L F ++ ++
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQ 425
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 533 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 592
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 593 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 652
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 653 LQSLSTLNLLANPF 666
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 42 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 101
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 102 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 159
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 160 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 534 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 593
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 594 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 653
Query: 275 RELHVLTLSRN 285
+ L L L N
Sbjct: 654 QSLSTLNLLAN 664
Score = 42.3 bits (95), Expect = 0.004
Identities = 36/139 (25%), Positives = 60/139 (43%), Gaps = 10/139 (7%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLI----------LANNQISTLVSRLFRMLAKLS 182
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+
Sbjct: 294 MTEIRLELNGIKSIPPGAFSPYRKLRRICPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLN 353
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
L L N +TDL VF + L++ + I + + L L L +N + L
Sbjct: 354 SLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSL 413
Query: 243 TSDEFISLKRLKKLKLDGN 261
F SL+ ++ L L N
Sbjct: 414 AKGTFTSLRAIQTLHLAQN 432
Score = 39.5 bits (88), Expect = 0.031
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 4/143 (2%)
Query: 334 NNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKL 392
+N + EIA Q L ++ + L + ++P+ F L L L+ NK++
Sbjct: 334 SNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDA 393
Query: 393 LSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVL 452
+ L L + NK+Q+L++ L AI ++L +N + CD C+ + ++ T +
Sbjct: 394 FQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLADFLRTNPI 452
Query: 453 NSTIRVLKCHSPLRLRGATFGSL 475
++ +C SP RL G +
Sbjct: 453 ETS--GARCASPRRLANKRIGQI 473
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 141 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 35.5 bits (78), Expect = 0.50
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 184 LDLSDNPLTDLNPE-VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
L L++N ++ L +FK + HL+ + I + + EL L N + +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
S F L L+ L L N++S I ++ F R + +L+L N+
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 641
Score = 33.1 bits (72), Expect = 2.7
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 432
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 540 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 598
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 599 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 658
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 659 LNLLANPFNCN 669
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 663
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 330 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 389
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 390 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 186 LTLNNN 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 205 LR 206
++
Sbjct: 431 IQ 432
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 429 RAIQTLHLAQNPF 441
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 431 IQTLHLAQN 439
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 111 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 171 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 819
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 660
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 661 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 721 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 775
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 776 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 67 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 125 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 185 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 222
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 660 LQSLSTLNLLANPF 673
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 734 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 777
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 778 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 836
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 818
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 819 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 177 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 335 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 451
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 452 DFLRTNPIETS--GARCASPRRLANKRIGQI 480
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 158 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 334 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 393
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 394 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 439
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 849 EGIFADVTSLSHLAIGANPLYCD 871
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 605
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 606 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 665
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 666 LNLLANPFNCN 676
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 663
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 330 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 389
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 390 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Score = 59.3 bits (137), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 186 LTLNNN 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 205 LR 206
++
Sbjct: 431 IQ 432
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 429 RAIQTLHLAQNPF 441
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 431 IQTLHLAQN 439
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 111 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 171 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 819
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 660
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 661 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 721 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 775
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 776 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 67 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 125 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 185 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 222
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 660 LQSLSTLNLLANPF 673
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 734 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 777
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 778 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 836
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 818
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 819 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 177 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 335 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 451
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 452 DFLRTNPIETS--GARCASPRRLANKRIGQI 480
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 158 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 334 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 393
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 394 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 439
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 849 EGIFADVTSLSHLAIGANPLYCD 871
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 605
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 606 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 665
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 666 LNLLANPFNCN 676
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 72.9 bits (171), Expect = 3e-12
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 3/174 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N R L+++ +N+ I +F L +L VL L N++ + F GL +L L L N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD-NPLTDLNPEVFKDI 202
+ S F +L+ L+ L L NN I ++ S F + L LDL + L ++ F+ +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKL 256
+L+ C ++ + + LV LEEL++ N F + F L LKKL
Sbjct: 196 FNLKYLNLGMCNIKDM-PNLTPLV-GLEELEMSGNHFPEIRPGSFHGLSSLKKL 247
Score = 65.7 bits (153), Expect = 4e-10
Identities = 52/165 (31%), Positives = 77/165 (46%), Gaps = 3/165 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N R LNL NN+ + AD FR L +L L L N I Q+ F L SL TL L +N +
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL-RIFKCRRCLLRRINTQIYHLV 226
+ + S F L+KL L L +NP+ + F + L R+ L I+ + +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
L+ L+LG K + + L L++L++ GN I F
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSF 238
Score = 55.2 bits (127), Expect = 6e-07
Identities = 63/287 (21%), Positives = 118/287 (41%), Gaps = 34/287 (11%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L +N + + + F+ + HL + + R +R+I ++ + L L+L +N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
S F L +L++L L N + I F R L L L +
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANLSLQ 362
++ + + P+V L+ + SGN+ P +I P HG+ SL+
Sbjct: 200 Y-LNLGMCNIKDMPNLTPLV-GLEELEMSGNHFP--------EIRPGSFHGLS----SLK 245
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
++ + N H R F L+ L L+++HN L +L L
Sbjct: 246 KL----WVMNSH-----------ERNAFDGLAS---LVELNLAHNNLSSLPHDLFTPLRY 287
Query: 423 IAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRG 469
+ E++L N W+CD C + ++ + ++ +CH+P+ +RG
Sbjct: 288 LVELHLHHNPWNCD-CDILWLAWWLREYIPTNSTCCGRCHAPMHMRG 333
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 6/108 (5%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I + +F GL NL+ LNL N+ + N L+ L EL + NH ++ +F L+SL
Sbjct: 187 ISEGAFEGLFNLKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
K L + N+ F LA L L+L+ N L+ L ++F +++L
Sbjct: 245 KKLWVMNSH----ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 288
Score = 44.4 bits (100), Expect = 0.001
Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 4/58 (6%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+L++L ++NS+ + +F GL +L LNL HNNL+S+ D F L L ELHL HN
Sbjct: 243 SLKKLWVMNSHERN----AFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 296
Score = 43.6 bits (98), Expect = 0.002
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P V L EL + ++ P I SF GL +L+ L + + S + F GL +L EL+L H
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWV----MNSHERNAFDGLASLVELNLAH 271
Query: 141 NHIEQMSSETFRHLTSLKTLILANN 165
N++ + + F L L L L +N
Sbjct: 272 NNLSSLPHDLFTPLRYLVELHLHHN 296
Score = 39.1 bits (87), Expect = 0.041
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L++ N+ + + L L L ++ N+ + +F GL +L +L + ++H
Sbjct: 197 NLKYLNLGMCNIKDMPNLT--PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSH- 253
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
F L SL L LA+N +S+L LF L L L L NP
Sbjct: 254 ---ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 297
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 72.9 bits (171), Expect = 3e-12
Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 8/147 (5%)
Query: 53 RDVHVVIIAAPPDRPNFLTIGPIFT-----QPAPFVNLRELHIV---NSNVPSIGQFSFW 104
R +H+++ A P P + F QP F LR L+ + N+ + I +F
Sbjct: 65 RCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFE 124
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L+NL+ L L N + S+ F+GL +L +L+L N IE + ++F+HL L+ L L N
Sbjct: 125 DLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHN 184
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPL 191
N+I+ LV F L + L L N L
Sbjct: 185 NRITHLVPGTFNHLESMKRLRLDSNTL 211
Score = 66.9 bits (156), Expect = 2e-10
Identities = 40/128 (31%), Positives = 61/128 (47%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L N I ++ FR L +L TL+L NNQI + S F L L L L N + ++
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
+ FK + L + ++ + +P+LE L L N +L F L+ +K+
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 256 LKLDGNQL 263
L+LD N L
Sbjct: 204 LRLDSNTL 211
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + FR L NL L L++N I+++ S F L +LK L L N+I ++
Sbjct: 83 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 142
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
+ F+ LA L L L N + L+P+ F QHL K R L N +I HLVP
Sbjct: 143 DRQAFKGLASLEQLYLHFNQIETLDPDSF---QHLP--KLERLFLH--NNRITHLVP 192
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/126 (26%), Positives = 62/126 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N+I + FR L L+ L L++N + + F+D+++L+ + ++ I+
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
Q + + LE+L L N + L D F L +L++L L N+++ +V F +
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 280 LTLSRN 285
L L N
Sbjct: 204 LRLDSN 209
Score = 41.5 bits (93), Expect = 0.008
Identities = 28/105 (26%), Positives = 50/105 (47%)
Query: 182 SILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY 241
SILDL N + ++ P F+ +++L ++RI + + + L+ L L +N +
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 242 LTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ F L L++L L NQ+ + + F +L L L NR
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNR 186
Score = 35.1 bits (77), Expect = 0.66
Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+Q I + F L L L +N++ L+RL + +N++ L L
Sbjct: 139 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 198
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK-CHSPLRLRGATFGSLSFEQ 479
E++ + L N HCD C + + T + + C P R++G + +++ E+
Sbjct: 199 ESMKRLRLDSNTLHCD-CEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEE 257
Query: 480 LD 481
L+
Sbjct: 258 LN 259
>AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat
transmembrane protein FLRT2 protein.
Length = 660
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 11/266 (4%)
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLT 281
+L + L L EN + ++ L +L++L LD N +S + D F L +L
Sbjct: 106 NLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLF 165
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS+N + N+I F + SL+ + GN L I
Sbjct: 166 LSKNHLSSVPVGLPVDLQELR---VDENRIAVISDMAFQNLT-SLERLIVDGNLLTNKGI 221
Query: 342 AI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A L ++ + SL P + HL+ L L N+++ P S + L+
Sbjct: 222 AEGTFSHLTKLKEFSIVRNSLSHPPPDL--PGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK 460
RLDIS+N+L+ L++ L + ++ N W CD CS + ++ + +R
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD-CSIKWVTEWLKYIPSSLNVRGFM 338
Query: 461 CHSPLRLRGATFGSLSFEQLDPCPTT 486
C P ++RG L+ L CPTT
Sbjct: 339 CQGPEQVRGMAVRELNMNLLS-CPTT 363
Score = 62.5 bits (145), Expect = 4e-09
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
PA N++ +H V + +F +N+RVL+L NN+ ++ L+ L ELHL
Sbjct: 81 PAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHL 140
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N I + E FR SLK L L+ N +S++ L L L + +N + ++
Sbjct: 141 DDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL---PVDLQELRVDENRIAVISD 197
Query: 197 EVFKDIQHL-RIFKCRRCLLRR-INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
F+++ L R+ L + I + + +L+E + N + D + L
Sbjct: 198 MAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD--LPGTHLI 255
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L NQ++ I F R+L L +S N+
Sbjct: 256 RLYLQDNQINHIPLTAFSNLRKLERLDISNNQ 287
Score = 47.2 bits (107), Expect = 2e-04
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDH 140
V+L+EL + + + I +F L +L L + N LT+ + F L L E +
Sbjct: 180 VDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVR 239
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + + T L L L +NQI+ + F L KL LD+S+N L L VF
Sbjct: 240 NSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFD 297
Query: 201 DIQHLRIFKCR 211
++ +L+ R
Sbjct: 298 NLSNLKQLTAR 308
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 82 FVNLRELH--IVNSNV---PSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
F NL L IV+ N+ I + +F L L+ ++ N+L+ D G +L L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD-LPGT-HLIRL 257
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L N I + F +L L+ L ++NNQ+ L +F L+ L L +NP
Sbjct: 258 YLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNP 311
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 663
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRAL 180
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 1e-08
Identities = 38/125 (30%), Positives = 62/125 (49%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L ++ + + ++ + +F ++ L L L N L + F+ L+ L L N I+
Sbjct: 87 LRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQ 146
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ + FR T LK L L NQIS + FR L L +L L++N +T + F +
Sbjct: 147 AIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPK 206
Query: 205 LRIFK 209
LR F+
Sbjct: 207 LRTFR 211
Score = 60.1 bits (139), Expect = 2e-08
Identities = 38/154 (24%), Positives = 67/154 (43%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L+ N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALR 181
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 59.7 bits (138), Expect = 3e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEV 185
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 186 LTLNNN 191
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 330 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 389
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 390 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 205 LR 206
++
Sbjct: 431 IQ 432
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 429 RAIQTLHLAQNPF 441
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 431 IQTLHLAQN 439
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 111 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQIS 170
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 171 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 819
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 660
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 661 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 721 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 775
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 776 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822
Score = 49.2 bits (112), Expect = 4e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALR 181
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 48.0 bits (109), Expect = 9e-05
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + E + E+ + L L +
Sbjct: 67 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGAVERG-AFDDMKELERLRLNRNQLHML 124
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 125 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLE 184
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 185 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 222
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 660 LQSLSTLNLLANPF 673
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 734 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 777
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 778 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 836
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 818
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 819 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L L+R
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLRLDKNQISCIEEG-A 176
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 177 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 335 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 451
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 452 DFLRTNPIETS--GARCASPRRLANKRIGQI 480
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 158 DLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 334 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 393
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 394 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 439
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 849 EGIFADVTSLSHLAIGANPLYCD 871
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 605
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 606 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 665
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 666 LNLLANPFNCN 676
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 72.9 bits (171), Expect = 3e-12
Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Query: 91 VNSNVPSIGQFS--FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSS 148
+N+N SI + + F L +L+ +NL++N ++ + F G +++ELHL N +E + S
Sbjct: 631 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 690
Query: 149 ETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
FR L L+TL+L NN+IS + + F L + +L L DN +T ++P F +Q L
Sbjct: 691 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSL 747
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/107 (34%), Positives = 62/107 (57%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+++++ N+ V I +F G ++ L+LT N L S+ + FRGL L L L +N I
Sbjct: 650 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 709
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L +++ L L +NQI+T+ F L LS L+L NP
Sbjct: 710 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 756
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L NQ
Sbjct: 145 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQ 204
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ L LF+ LS LDLS+N + + + F+ L+ + + + I + +
Sbjct: 205 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 264
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N + F + +L+ +L N L
Sbjct: 265 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 59.7 bits (138), Expect = 3e-08
Identities = 38/154 (24%), Positives = 66/154 (42%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + V F + L L L+ N +
Sbjct: 146 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQL 205
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F++ +L L L+ N I + + FR L L L N ++ + F+ ++
Sbjct: 206 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 265
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + I ++ +P+L L N
Sbjct: 266 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 299
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 414 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 473
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLN 195
N I + + F+ L +L L L +N+I +L F L + L L+ NP + D N
Sbjct: 474 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 530
Score = 58.8 bits (136), Expect = 5e-08
Identities = 39/126 (30%), Positives = 58/126 (46%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L +L +L L +N + + F D++ L + R L +
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ L LDL EN + + F LK L+LD NQ+S I + F R L V
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 269
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 270 LTLNNN 275
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/122 (27%), Positives = 63/122 (51%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 395 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 454
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ F L +L+ L+L N+I+ + F+ L LS+L L DN + L F ++
Sbjct: 455 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 514
Query: 205 LR 206
++
Sbjct: 515 IQ 516
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/133 (24%), Positives = 66/133 (49%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 393 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 452
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L +F L L +L L+ N + + P+ F+D+Q+L + ++ + + +
Sbjct: 453 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 512
Query: 227 PRLEELDLGENLF 239
++ L L +N F
Sbjct: 513 RAIQTLHLAQNPF 525
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 395 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 454
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
DL VF + L++ + I + + L L L +N + L F SL+
Sbjct: 455 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 514
Query: 253 LKKLKLDGN 261
++ L L N
Sbjct: 515 IQTLHLAQN 523
Score = 52.8 bits (121), Expect = 3e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + + + + + F Q L L+L+ N + ++ FRG +L L LD N I
Sbjct: 195 LERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 254
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 255 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/109 (31%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
Query: 84 NLRELHIVNSNVPSI-GQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
N+ EL++ + + GQ S + + L++++L++N ++S+ +F + LT L L +N
Sbjct: 846 NVTELYLDGNQFTLVPGQLSTF--KYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNA 903
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
++ + F+ L SL+ L L N ISTL +F + LS L + NPL
Sbjct: 904 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 952
Score = 52.0 bits (119), Expect = 5e-06
Identities = 63/288 (21%), Positives = 115/288 (39%), Gaps = 14/288 (4%)
Query: 156 SLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
S L L NN+IS L + +F+ L L ++LS+N ++++ F+ +
Sbjct: 625 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 684
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L I + ++ + L L L N + +D F L+ ++ L L NQ++ + F
Sbjct: 685 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL 744
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK-------IDRFHLQTFAPVVDSLK 327
+ L L L N ++ N + + LQ A +
Sbjct: 745 QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 804
Query: 328 TINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSR 387
G LP + L + V +N L+ +P+ +++ L L N+ +
Sbjct: 805 EGQEEGGCLPRPQCPQECACLDTV--VRCSNKHLRALPKGI---PKNVTELYLDGNQFTL 859
Query: 388 FPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
P + LS K+LQ +D+S+NK+ +LS + + + L N C
Sbjct: 860 VPGQ-LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 906
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 66/154 (42%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L L L+ N L
Sbjct: 146 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQL 205
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L +F++ Q L ++ I + + L+ L L +N + F +L+
Sbjct: 206 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 265
Query: 252 RLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L L+ N ++ I + F +L L N
Sbjct: 266 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 299
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
+++ N I R H FA + L+ + N + + E + E+ + L L +
Sbjct: 151 ELNGNNITRIHKNDFAGL-KQLRVLQLMENQIGVVERG-AFDDMKELERLRLNRNQLHML 208
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F N+ L LDLS N + P K L+ L + N++ + E + L +
Sbjct: 209 PELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLE 268
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN S+ N + + T L+S CH
Sbjct: 269 VLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 306
Score = 48.8 bits (111), Expect = 5e-05
Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ V+ F +EL L L+R
Sbjct: 143 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNR 202
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N+ D+S N I + F D LK + N + E
Sbjct: 203 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATD-LKNLQLDKNQISCIEEG-A 260
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L + + L N ++ IP + F + L L N L
Sbjct: 261 FRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 48.0 bits (109), Expect = 9e-05
Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 107 QNLRVLNLTHNNLTSVVADN-FRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
Q+ L L +N ++ + A F+ L +L +++L +N + ++ F S+ L L N
Sbjct: 624 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 683
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
Q+ ++ S +FR L L L L +N ++ ++ + F ++++R+ + ++ +
Sbjct: 684 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 743
Query: 226 VPRLEELDLGENLF 239
+ L L+L N F
Sbjct: 744 LQSLSTLNLLANPF 757
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP EC C T V C + H+R +P + ++V + + N T+ P
Sbjct: 818 CPQECACL---------DTVVRCSNKHLRALPKG-IPKNVTELYLDG-----NQFTLVP- 861
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
Q + F L+ + + N+ + S+ SF + L L L++N L + F+GL +L
Sbjct: 862 -GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRL 920
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F +TSL L + N +
Sbjct: 921 LSLHGNDISTLQEGIFADVTSLSHLAIGANPL 952
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Query: 132 NLTELHLDHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
N+TEL+LD N + + TF++L + + L+NN+IS+L + F +++L+ L LS N
Sbjct: 846 NVTELYLDGNQFTLVPGQLSTFKYL---QLVDLSNNKISSLSNSSFTNMSQLTTLILSYN 902
Query: 190 PLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + P F+ ++ LR+ + + I+ V L L +G N
Sbjct: 903 ALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 950
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
Query: 326 LKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNK 384
L+ I+ S N + EIA Q L ++ + L + ++P+ F L L L+ NK
Sbjct: 419 LRRIDLSNNQIA--EIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 476
Query: 385 LSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNML 444
++ + L L + NK+Q+L++ L AI ++L +N + CD C+ +
Sbjct: 477 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICD-CNLKWLA 535
Query: 445 LYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
++ T + ++ +C SP RL G +
Sbjct: 536 DFLRTNPIETS--GARCASPRRLANKRIGQI 564
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 242 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 36.3 bits (80), Expect = 0.29
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRX 287
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 418 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKI 477
Query: 288 XXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
+ NKI TF + +++T++ + N
Sbjct: 478 NCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTS-LRAIQTLHLAQN 523
Score = 35.1 bits (77), Expect = 0.66
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
V L+N + + + FT L L LS+N L P + L+ L + N + TL
Sbjct: 873 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 932
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E + +++ + + N +CD
Sbjct: 933 EGIFADVTSLSHLAIGANPLYCD 955
Score = 31.9 bits (69), Expect = 6.2
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 306 ISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIP 365
+++N+I + LK IN S N + E + + + L L+ I
Sbjct: 631 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDG-AFEGAASVSELHLTANQLESIR 689
Query: 366 QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAE 425
F + L L L N++S + + ++ L + N++ T+S L++++
Sbjct: 690 SGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLST 749
Query: 426 VNLMKNNWHCD 436
+NL+ N ++C+
Sbjct: 750 LNLLANPFNCN 760
>AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein.
Length = 706
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 11/266 (4%)
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI--VDNMFGRNRELHVLT 281
+L + L L EN + ++ L +L++L LD N +S + D F L +L
Sbjct: 152 NLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLF 211
Query: 282 LSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI 341
LS+N + N+I F + SL+ + GN L I
Sbjct: 212 LSKNHLSSVPVGLPVDLQELR---VDENRIAVISDMAFQNLT-SLERLIVDGNLLTNKGI 267
Query: 342 AI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQ 400
A L ++ + SL P + HL+ L L N+++ P S + L+
Sbjct: 268 AEGTFSHLTKLKEFSIVRNSLSHPPPDL--PGTHLIRLYLQDNQINHIPLTAFSNLRKLE 325
Query: 401 RLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLK 460
RLDIS+N+L+ L++ L + ++ N W CD CS + ++ + +R
Sbjct: 326 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD-CSIKWVTEWLKYIPSSLNVRGFM 384
Query: 461 CHSPLRLRGATFGSLSFEQLDPCPTT 486
C P ++RG L+ L CPTT
Sbjct: 385 CQGPEQVRGMAVRELNMNLLS-CPTT 409
Score = 62.5 bits (145), Expect = 4e-09
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
PA N++ +H V + +F +N+RVL+L NN+ ++ L+ L ELHL
Sbjct: 127 PAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHL 186
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N I + E FR SLK L L+ N +S++ L L L + +N + ++
Sbjct: 187 DDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGL---PVDLQELRVDENRIAVISD 243
Query: 197 EVFKDIQHL-RIFKCRRCLLRR-INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
F+++ L R+ L + I + + +L+E + N + D + L
Sbjct: 244 MAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD--LPGTHLI 301
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L L NQ++ I F R+L L +S N+
Sbjct: 302 RLYLQDNQINHIPLTAFSNLRKLERLDISNNQ 333
Score = 47.2 bits (107), Expect = 2e-04
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTS--VVADNFRGLINLTELHLDH 140
V+L+EL + + + I +F L +L L + N LT+ + F L L E +
Sbjct: 226 VDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVR 285
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N + + T L L L +NQI+ + F L KL LD+S+N L L VF
Sbjct: 286 NSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFD 343
Query: 201 DIQHLRIFKCR 211
++ +L+ R
Sbjct: 344 NLSNLKQLTAR 354
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 82 FVNLRELH--IVNSNV---PSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTEL 136
F NL L IV+ N+ I + +F L L+ ++ N+L+ D G +L L
Sbjct: 246 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD-LPGT-HLIRL 303
Query: 137 HLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+L N I + F +L L+ L ++NNQ+ L +F L+ L L +NP
Sbjct: 304 YLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNP 357
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 72.1 bits (169), Expect = 5e-12
Identities = 61/206 (29%), Positives = 93/206 (45%), Gaps = 1/206 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A LR L + + S+ + L LR L +NL V RGL NLT HL+
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALREL-AAFDNLFRRVPGALRGLANLTHAHLE 190
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
IE ++S + + L L++L L N++ + + F L L L+DN L +L + F
Sbjct: 191 RGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAF 250
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ ++ LR L R+ + + LE L L N ++ F +L L L L+
Sbjct: 251 RGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLN 310
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRN 285
GN+L+V+ F L L L RN
Sbjct: 311 GNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/212 (30%), Positives = 96/212 (45%), Gaps = 24/212 (11%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN-HIEQMSSETFRHLTS 156
+G+ +F L +LR L+L HNNL+ + F+GL L EL L HN + + + TF L+
Sbjct: 77 LGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSR 136
Query: 157 LKTLILANNQISTLVSRLFRMLAKLSILDLSDN-------------PLTDLNPE------ 197
L+ L LA ++ ++ RL L L L DN LT + E
Sbjct: 137 LRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEA 196
Query: 198 ----VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++ LR + +R ++ + LE L L +NL L +D F L+RL
Sbjct: 197 VASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRL 256
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L L GN L + F EL +L L RN
Sbjct: 257 RTLNLGGNALDRVARAWFADLAELELLYLDRN 288
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 3/230 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTL 170
++L N L + F L +L L L HN++ ++ F+ L L L LA+N + L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
+R F L++L LDL+ L + + ++ LR L RR+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLA-NLT 185
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXX 290
L + + S L+RL+ L L N++ + FG L L L+ N
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNE 340
++ N +DR FA + + L+ + N++ E
Sbjct: 246 PADAFRGLRRLRTLNLGGNALDRVARAWFADLAE-LELLYLDRNSIAFVE 294
Score = 50.4 bits (115), Expect = 2e-05
Identities = 75/343 (21%), Positives = 128/343 (37%), Gaps = 32/343 (9%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN-PLTDL 194
+ LD N + + F L SL+ L L +N +S + F+ L +L+ L L+ N L L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ F + LR C L + ++ +P L EL +NLF+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLT 185
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L+ ++ + + R L L+L NR ++ N +
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEH 374
F + L+T+N GN L+ +A LA L L + +N + E
Sbjct: 246 PADAFRGL-RRLRTLNLGGN--ALDRVA-------RAWFADLAELELLYLDRNSIAFVEE 295
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
+LS L L ++ N+L L+ Q + + L +N W
Sbjct: 296 GAFQNLSG----------------LLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWC 339
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
CD C + +M + + + C SP + G ++F
Sbjct: 340 CD-CRLEWLRDWMEG---SGRVTDVPCASPGSVAGLDLSQVTF 378
Score = 44.4 bits (100), Expect = 0.001
Identities = 32/89 (35%), Positives = 43/89 (48%)
Query: 102 SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLI 161
+F GL+ LR LNL N L V F L L L+LD N I + F++L+ L L
Sbjct: 249 AFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALH 308
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNP 190
L N+++ L F+ L L L NP
Sbjct: 309 LNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 72.1 bits (169), Expect = 5e-12
Identities = 61/206 (29%), Positives = 93/206 (45%), Gaps = 1/206 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A LR L + + S+ + L LR L +NL V RGL NLT HL+
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALREL-AAFDNLFRRVPGALRGLANLTHAHLE 190
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
IE ++S + + L L++L L N++ + + F L L L+DN L +L + F
Sbjct: 191 RGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAF 250
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ ++ LR L R+ + + LE L L N ++ F +L L L L+
Sbjct: 251 RGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLN 310
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRN 285
GN+L+V+ F L L L RN
Sbjct: 311 GNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/212 (30%), Positives = 96/212 (45%), Gaps = 24/212 (11%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN-HIEQMSSETFRHLTS 156
+G+ +F L +LR L+L HNNL+ + F+GL L EL L HN + + + TF L+
Sbjct: 77 LGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSR 136
Query: 157 LKTLILANNQISTLVSRLFRMLAKLSILDLSDN-------------PLTDLNPE------ 197
L+ L LA ++ ++ RL L L L DN LT + E
Sbjct: 137 LRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEA 196
Query: 198 ----VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++ LR + +R ++ + LE L L +NL L +D F L+RL
Sbjct: 197 VASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRL 256
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L L GN L + F EL +L L RN
Sbjct: 257 RTLNLGGNALDRVARAWFADLAELELLYLDRN 288
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 3/230 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTL 170
++L N L + F L +L L L HN++ ++ F+ L L L LA+N + L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
+R F L++L LDL+ L + + ++ LR L RR+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLA-NLT 185
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXX 290
L + + S L+RL+ L L N++ + FG L L L+ N
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNE 340
++ N +DR FA + + L+ + N++ E
Sbjct: 246 PADAFRGLRRLRTLNLGGNALDRVARAWFADLAE-LELLYLDRNSIAFVE 294
Score = 50.4 bits (115), Expect = 2e-05
Identities = 75/343 (21%), Positives = 128/343 (37%), Gaps = 32/343 (9%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN-PLTDL 194
+ LD N + + F L SL+ L L +N +S + F+ L +L+ L L+ N L L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ F + LR C L + ++ +P L EL +NLF+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLT 185
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L+ ++ + + R L L+L NR ++ N +
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEH 374
F + L+T+N GN L+ +A LA L L + +N + E
Sbjct: 246 PADAFRGL-RRLRTLNLGGN--ALDRVA-------RAWFADLAELELLYLDRNSIAFVEE 295
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
+LS L L ++ N+L L+ Q + + L +N W
Sbjct: 296 GAFQNLSG----------------LLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWC 339
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
CD C + +M + + + C SP + G ++F
Sbjct: 340 CD-CRLEWLRDWMEG---SGRVTDVPCASPGSVAGLDLSQVTF 378
Score = 44.4 bits (100), Expect = 0.001
Identities = 32/89 (35%), Positives = 43/89 (48%)
Query: 102 SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLI 161
+F GL+ LR LNL N L V F L L L+LD N I + F++L+ L L
Sbjct: 249 AFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALH 308
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNP 190
L N+++ L F+ L L L NP
Sbjct: 309 LNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 72.1 bits (169), Expect = 5e-12
Identities = 75/283 (26%), Positives = 118/283 (41%), Gaps = 6/283 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L+ L+L++N L+++ F GL +L L L N + M F L++L L L N
Sbjct: 83 LSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLN 142
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI + F L L L++ DN L + P F + L RC L +
Sbjct: 143 QIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALAR 202
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVD--NMFGRNRELHVLTLS 283
+P L L L E L + L +LK+L++ +D ++ G N L L ++
Sbjct: 203 LPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLN--LSSLAIT 260
Query: 284 RNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI 343
R D+S N I + +P+V L+ + SG L + A
Sbjct: 261 RCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLV-RLQELRLSGACL-TSIAAH 318
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLS 386
L H + +A+ +LQ + + F + LV L LS N L+
Sbjct: 319 AFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLT 361
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 57/110 (51%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I N+ S+ + + L LRVL+L+ N ++++ A L+ L EL L
Sbjct: 252 LNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGAC 311
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ +++ F LT+ L +A+N + TL F KL L LS NPLT
Sbjct: 312 LTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLT 361
Score = 52.8 bits (121), Expect = 3e-06
Identities = 62/273 (22%), Positives = 103/273 (37%), Gaps = 4/273 (1%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L+ N++ L + L+ L LDLS N L+ L P F +Q L + + LR +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ + L LDL N F L L+KL++ N L + F +L
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS-GNNLPL 338
LTL R + I R + LK + +L
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRG-LGQLKELEIHLWPSLEA 243
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
+ ++ + + + + +L +P + L LDLS N +S P + LS
Sbjct: 244 LDPGSLVGL--NLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVR 301
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LQ L +S L +++ L A +++ N
Sbjct: 302 LQELRLSGACLTSIAAHAFHGLTAFHLLDVADN 334
Score = 52.0 bits (119), Expect = 5e-06
Identities = 79/276 (28%), Positives = 109/276 (39%), Gaps = 25/276 (9%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + + + ++ +F GLQ+L L L N L + F GL LT L L N I
Sbjct: 86 LQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIV 145
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSIL-----DLSDNP---LTDLNP 196
F L SL+ L + +N + + F LAKLS L +LS P L L
Sbjct: 146 LFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPA 205
Query: 197 EVFKDIQHLRIFKCRRCLLR---RINTQIYHLVPRLEELD----LGENLFKY------LT 243
V ++ L I + LR ++ HL P LE LD +G NL L+
Sbjct: 206 LVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLS 265
Query: 244 SDEFISLKR---LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXX 300
S F +L L+ L L N +S I L L LS
Sbjct: 266 SVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTA 325
Query: 301 XXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D++ N + +T P D L T+ SGN L
Sbjct: 326 FHLLDVADNALQTLE-ETAFPSPDKLVTLRLSGNPL 360
Score = 49.2 bits (112), Expect = 4e-05
Identities = 71/307 (23%), Positives = 111/307 (36%), Gaps = 14/307 (4%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L N + + L+ L+ L L+ NQ+STL F L L L L N L +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
P VF + L + R + + + L++L++G+N ++ F L +L
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L L+ LS + R L L L + K H
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRE--------LDIGRLPAGALRGLGQLKELEIH 236
Query: 316 LQTFAPVVD--SLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLS---LQEIPQNFF 369
L +D SL +N S + N ++ Q L + + + +LS + IP
Sbjct: 237 LWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRL 296
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ L L LS L+ LD++ N LQTL E + + + L
Sbjct: 297 SPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLS 356
Query: 430 KNNWHCD 436
N CD
Sbjct: 357 GNPLTCD 363
Score = 46.0 bits (104), Expect = 4e-04
Identities = 58/227 (25%), Positives = 100/227 (44%), Gaps = 26/227 (11%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L + + + +G F GL L +L+L N + + F L +L +L + NH+
Sbjct: 109 SLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHL 168
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL----VSRLFRMLA-KLSILDLSDNP-------- 190
++ F L L TL L +ST+ ++RL ++A +L LD+ P
Sbjct: 169 VFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLG 228
Query: 191 -LTDLNPEVFKDIQ----------HLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENL 238
L +L ++ ++ +L RC L + Q +YHL L LDL +N
Sbjct: 229 QLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHL-SFLRVLDLSQNP 287
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + L RL++L+L G L+ I + F H+L ++ N
Sbjct: 288 ISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADN 334
Score = 39.5 bits (88), Expect = 0.031
Identities = 57/250 (22%), Positives = 92/250 (36%), Gaps = 10/250 (4%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+LDLS N L L + + L+ L + +H + L L L N + +
Sbjct: 64 LLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIM 123
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
F L L L L NQ+ + +D FG L L + N
Sbjct: 124 GPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLS 183
Query: 303 XXDISHNKIDRFHLQTFA--PVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANL 359
+ + A P + +L+ LP + + Q+ EIH
Sbjct: 184 TLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIH----LWP 239
Query: 360 SLQEI-PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
SL+ + P + N L +L ++ LS PF+ L FL+ LD+S N + + + L
Sbjct: 240 SLEALDPGSLVGLN--LSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLS 297
Query: 419 RLEAIAEVNL 428
L + E+ L
Sbjct: 298 PLVRLQELRL 307
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat
neuronal 6D protein.
Length = 593
Score = 72.1 bits (169), Expect = 5e-12
Identities = 75/283 (26%), Positives = 118/283 (41%), Gaps = 6/283 (2%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L L+ L+L++N L+++ F GL +L L L N + M F L++L L L N
Sbjct: 83 LSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLN 142
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHL 225
QI + F L L L++ DN L + P F + L RC L +
Sbjct: 143 QIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALAR 202
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVD--NMFGRNRELHVLTLS 283
+P L L L E L + L +LK+L++ +D ++ G N L L ++
Sbjct: 203 LPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLN--LSSLAIT 260
Query: 284 RNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI 343
R D+S N I + +P+V L+ + SG L + A
Sbjct: 261 RCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLV-RLQELRLSGACL-TSIAAH 318
Query: 344 VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLS 386
L H + +A+ +LQ + + F + LV L LS N L+
Sbjct: 319 AFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLT 361
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 57/110 (51%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I N+ S+ + + L LRVL+L+ N ++++ A L+ L EL L
Sbjct: 252 LNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGAC 311
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+ +++ F LT+ L +A+N + TL F KL L LS NPLT
Sbjct: 312 LTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLT 361
Score = 52.8 bits (121), Expect = 3e-06
Identities = 62/273 (22%), Positives = 103/273 (37%), Gaps = 4/273 (1%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L+ N++ L + L+ L LDLS N L+ L P F +Q L + + LR +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ + L LDL N F L L+KL++ N L + F +L
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 280 LTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFS-GNNLPL 338
LTL R + I R + LK + +L
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRG-LGQLKELEIHLWPSLEA 243
Query: 339 NEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKF 398
+ ++ + + + + +L +P + L LDLS N +S P + LS
Sbjct: 244 LDPGSLVGL--NLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVR 301
Query: 399 LQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKN 431
LQ L +S L +++ L A +++ N
Sbjct: 302 LQELRLSGACLTSIAAHAFHGLTAFHLLDVADN 334
Score = 52.0 bits (119), Expect = 5e-06
Identities = 79/276 (28%), Positives = 109/276 (39%), Gaps = 25/276 (9%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL + + + ++ +F GLQ+L L L N L + F GL LT L L N I
Sbjct: 86 LQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIV 145
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSIL-----DLSDNP---LTDLNP 196
F L SL+ L + +N + + F LAKLS L +LS P L L
Sbjct: 146 LFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPA 205
Query: 197 EVFKDIQHLRIFKCRRCLLR---RINTQIYHLVPRLEELD----LGENLFKY------LT 243
V ++ L I + LR ++ HL P LE LD +G NL L+
Sbjct: 206 LVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLS 265
Query: 244 SDEFISLKR---LKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXX 300
S F +L L+ L L N +S I L L LS
Sbjct: 266 SVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTA 325
Query: 301 XXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
D++ N + +T P D L T+ SGN L
Sbjct: 326 FHLLDVADNALQTLE-ETAFPSPDKLVTLRLSGNPL 360
Score = 49.2 bits (112), Expect = 4e-05
Identities = 71/307 (23%), Positives = 111/307 (36%), Gaps = 14/307 (4%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLN 195
L L N + + L+ L+ L L+ NQ+STL F L L L L N L +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 196 PEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKK 255
P VF + L + R + + + L++L++G+N ++ F L +L
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 256 LKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFH 315
L L+ LS + R L L L + K H
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRE--------LDIGRLPAGALRGLGQLKELEIH 236
Query: 316 LQTFAPVVD--SLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLS---LQEIPQNFF 369
L +D SL +N S + N ++ Q L + + + +LS + IP
Sbjct: 237 LWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRL 296
Query: 370 TYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLM 429
+ L L LS L+ LD++ N LQTL E + + + L
Sbjct: 297 SPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLS 356
Query: 430 KNNWHCD 436
N CD
Sbjct: 357 GNPLTCD 363
Score = 46.0 bits (104), Expect = 4e-04
Identities = 58/227 (25%), Positives = 100/227 (44%), Gaps = 26/227 (11%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L L + + + +G F GL L +L+L N + + F L +L +L + NH+
Sbjct: 109 SLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHL 168
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL----VSRLFRMLA-KLSILDLSDNP-------- 190
++ F L L TL L +ST+ ++RL ++A +L LD+ P
Sbjct: 169 VFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLG 228
Query: 191 -LTDLNPEVFKDIQ----------HLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENL 238
L +L ++ ++ +L RC L + Q +YHL L LDL +N
Sbjct: 229 QLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHL-SFLRVLDLSQNP 287
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ + L RL++L+L G L+ I + F H+L ++ N
Sbjct: 288 ISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADN 334
Score = 39.5 bits (88), Expect = 0.031
Identities = 57/250 (22%), Positives = 92/250 (36%), Gaps = 10/250 (4%)
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
+LDLS N L L + + L+ L + +H + L L L N + +
Sbjct: 64 LLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIM 123
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
F L L L L NQ+ + +D FG L L + N
Sbjct: 124 GPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLS 183
Query: 303 XXDISHNKIDRFHLQTFA--PVVDSLKTINFSGNNLPLNEIAIVLQILP-EIHGVGLANL 359
+ + A P + +L+ LP + + Q+ EIH
Sbjct: 184 TLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIH----LWP 239
Query: 360 SLQEI-PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
SL+ + P + N L +L ++ LS PF+ L FL+ LD+S N + + + L
Sbjct: 240 SLEALDPGSLVGLN--LSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLS 297
Query: 419 RLEAIAEVNL 428
L + E+ L
Sbjct: 298 PLVRLQELRL 307
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 72.1 bits (169), Expect = 5e-12
Identities = 43/126 (34%), Positives = 62/126 (49%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL+ LRVL L N + +V F + L L L N I
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAI 121
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ + + FR T LK L L NQIS + FR L L +L L++N +T + F +
Sbjct: 122 QAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMP 181
Query: 204 HLRIFK 209
LR F+
Sbjct: 182 KLRTFR 187
Score = 57.6 bits (133), Expect = 1e-07
Identities = 33/107 (30%), Positives = 54/107 (50%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR L ++ + + ++ + +F ++ L L+L+ N + ++ FRG +L L LD N I
Sbjct: 87 LRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRGATDLKNLQLDKNQIS 146
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+T+ F + KL L N L
Sbjct: 147 CIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 193
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/102 (31%), Positives = 51/102 (50%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L+L+ N +T ++ F ++ LR+ + + + + + LE LDL EN + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F LK L+LD NQ+S I + F R L VLTL+ N
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNN 167
Score = 51.6 bits (118), Expect = 7e-06
Identities = 33/131 (25%), Positives = 56/131 (42%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L L NN+T + ++F GL L L L N I + F + L+ L L+ N
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENA 120
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I + + FR L L L N ++ + F+ ++ L + + I ++ +
Sbjct: 121 IQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHM 180
Query: 227 PRLEELDLGEN 237
P+L L N
Sbjct: 181 PKLRTFRLHSN 191
Score = 48.8 bits (111), Expect = 5e-05
Identities = 33/132 (25%), Positives = 57/132 (43%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L L+ N+I ++ F L L+ L L NQI + F + +L LDLS+N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAI 121
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
+ + F+ L+ + + + I + + LE L L N + F +
Sbjct: 122 QAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMP 181
Query: 252 RLKKLKLDGNQL 263
+L+ +L N L
Sbjct: 182 KLRTFRLHSNHL 193
Score = 48.8 bits (111), Expect = 5e-05
Identities = 26/96 (27%), Positives = 50/96 (52%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + S+ F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 285 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 344
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I+ L +F L L +L L+ N + + P+ F+D+
Sbjct: 345 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/94 (27%), Positives = 49/94 (52%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + SI +F + LR ++L++N + + D F+GL +L L L N I
Sbjct: 287 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 346
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRML 178
+ F L +L+ L+L N+I+ + F+ L
Sbjct: 347 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 41.5 bits (93), Expect = 0.008
Identities = 24/75 (32%), Positives = 40/75 (53%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQI+ + F+ L L+ L L N +T
Sbjct: 287 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 346
Query: 193 DLNPEVFKDIQHLRI 207
DL VF + L++
Sbjct: 347 DLPRGVFGGLYTLQL 361
Score = 39.5 bits (88), Expect = 0.031
Identities = 23/75 (30%), Positives = 38/75 (50%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + I +F GL++L L L N +T + F GL L L L+
Sbjct: 306 SPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 365
Query: 140 HNHIEQMSSETFRHL 154
N I + + F+ L
Sbjct: 366 ANKINCIRPDAFQDL 380
Score = 37.9 bits (84), Expect = 0.094
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+L+ L + + + I + +F L+ L VL L +NN+T++ +F + L L NH+
Sbjct: 134 DLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 193
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 2/112 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E L+L N + ++F LK+L+ L+L NQ+ + F +EL L LS
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSE 118
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
N + N+I F + L+ + + NN+
Sbjct: 119 NAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFR-ALRGLEVLTLNNNNI 169
Score = 35.5 bits (78), Expect = 0.50
Identities = 26/115 (22%), Positives = 46/115 (40%)
Query: 348 LPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHN 407
L ++ + L + + + F + L LDLS N + P K L+ L + N
Sbjct: 84 LKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRGATDLKNLQLDKN 143
Query: 408 KLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
++ + E + L + + L NN S+ N + + T L+S CH
Sbjct: 144 QISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCH 198
Score = 34.7 bits (76), Expect = 0.88
Identities = 18/59 (30%), Positives = 30/59 (50%)
Query: 228 RLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+L +DL N + D F L+ L L L GN+++ + +FG L +L L+ N+
Sbjct: 310 KLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 368
Score = 33.5 bits (73), Expect = 2.0
Identities = 23/95 (24%), Positives = 40/95 (42%)
Query: 360 SLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQR 419
++ I +N F + L L L N++ K L+RLD+S N +Q + + +
Sbjct: 72 NITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRG 131
Query: 420 LEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNS 454
+ + L KN C + A L + LN+
Sbjct: 132 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 166
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 72.1 bits (169), Expect = 5e-12
Identities = 61/206 (29%), Positives = 93/206 (45%), Gaps = 1/206 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A LR L + + S+ + L LR L +NL V RGL NLT HL+
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALREL-AAFDNLFRRVPGALRGLANLTHAHLE 190
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
IE ++S + + L L++L L N++ + + F L L L+DN L +L + F
Sbjct: 191 RGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAF 250
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ ++ LR L R+ + + LE L L N ++ F +L L L L+
Sbjct: 251 RGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLN 310
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRN 285
GN+L+V+ F L L L RN
Sbjct: 311 GNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/212 (30%), Positives = 96/212 (45%), Gaps = 24/212 (11%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN-HIEQMSSETFRHLTS 156
+G+ +F L +LR L+L HNNL+ + F+GL L EL L HN + + + TF L+
Sbjct: 77 LGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSR 136
Query: 157 LKTLILANNQISTLVSRLFRMLAKLSILDLSDN-------------PLTDLNPE------ 197
L+ L LA ++ ++ RL L L L DN LT + E
Sbjct: 137 LRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEA 196
Query: 198 ----VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++ LR + +R ++ + LE L L +NL L +D F L+RL
Sbjct: 197 VASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRL 256
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L L GN L + F EL +L L RN
Sbjct: 257 RTLNLGGNALDRVARAWFADLAELELLYLDRN 288
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 3/230 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTL 170
++L N L + F L +L L L HN++ ++ F+ L L L LA+N + L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
+R F L++L LDL+ L + + ++ LR L RR+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLA-NLT 185
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXX 290
L + + S L+RL+ L L N++ + FG L L L+ N
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNE 340
++ N +DR FA + + L+ + N++ E
Sbjct: 246 PADAFRGLRRLRTLNLGGNALDRVARAWFADLAE-LELLYLDRNSIAFVE 294
Score = 50.4 bits (115), Expect = 2e-05
Identities = 75/343 (21%), Positives = 128/343 (37%), Gaps = 32/343 (9%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN-PLTDL 194
+ LD N + + F L SL+ L L +N +S + F+ L +L+ L L+ N L L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ F + LR C L + ++ +P L EL +NLF+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLT 185
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L+ ++ + + R L L+L NR ++ N +
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEH 374
F + L+T+N GN L+ +A LA L L + +N + E
Sbjct: 246 PADAFRGL-RRLRTLNLGGN--ALDRVA-------RAWFADLAELELLYLDRNSIAFVEE 295
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
+LS L L ++ N+L L+ Q + + L +N W
Sbjct: 296 GAFQNLSG----------------LLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWC 339
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
CD C + +M + + + C SP + G ++F
Sbjct: 340 CD-CRLEWLRDWMEG---SGRVTDVPCASPGSVAGLDLSQVTF 378
Score = 44.4 bits (100), Expect = 0.001
Identities = 32/89 (35%), Positives = 43/89 (48%)
Query: 102 SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLI 161
+F GL+ LR LNL N L V F L L L+LD N I + F++L+ L L
Sbjct: 249 AFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALH 308
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNP 190
L N+++ L F+ L L L NP
Sbjct: 309 LNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 72.1 bits (169), Expect = 5e-12
Identities = 61/206 (29%), Positives = 93/206 (45%), Gaps = 1/206 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A LR L + + S+ + L LR L +NL V RGL NLT HL+
Sbjct: 132 AALSRLRRLDLAACRLFSVPERLLAELPALREL-AAFDNLFRRVPGALRGLANLTHAHLE 190
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
IE ++S + + L L++L L N++ + + F L L L+DN L +L + F
Sbjct: 191 RGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAF 250
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLD 259
+ ++ LR L R+ + + LE L L N ++ F +L L L L+
Sbjct: 251 RGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLN 310
Query: 260 GNQLSVIVDNMFGRNRELHVLTLSRN 285
GN+L+V+ F L L L RN
Sbjct: 311 GNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/212 (30%), Positives = 96/212 (45%), Gaps = 24/212 (11%)
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN-HIEQMSSETFRHLTS 156
+G+ +F L +LR L+L HNNL+ + F+GL L EL L HN + + + TF L+
Sbjct: 77 LGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSR 136
Query: 157 LKTLILANNQISTLVSRLFRMLAKLSILDLSDN-------------PLTDLNPE------ 197
L+ L LA ++ ++ RL L L L DN LT + E
Sbjct: 137 LRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEA 196
Query: 198 ----VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++ LR + +R ++ + LE L L +NL L +D F L+RL
Sbjct: 197 VASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRL 256
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+ L L GN L + F EL +L L RN
Sbjct: 257 RTLNLGGNALDRVARAWFADLAELELLYLDRN 288
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 3/230 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTL 170
++L N L + F L +L L L HN++ ++ F+ L L L LA+N + L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLE 230
+R F L++L LDL+ L + + ++ LR L RR+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLA-NLT 185
Query: 231 ELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXX 290
L + + S L+RL+ L L N++ + FG L L L+ N
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 291 XXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNE 340
++ N +DR FA + + L+ + N++ E
Sbjct: 246 PADAFRGLRRLRTLNLGGNALDRVARAWFADLAE-LELLYLDRNSIAFVE 294
Score = 50.4 bits (115), Expect = 2e-05
Identities = 75/343 (21%), Positives = 128/343 (37%), Gaps = 32/343 (9%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN-PLTDL 194
+ LD N + + F L SL+ L L +N +S + F+ L +L+ L L+ N L L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ F + LR C L + ++ +P L EL +NLF+ + L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLT 185
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
L+ ++ + + R L L+L NR ++ N +
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEH 374
F + L+T+N GN L+ +A LA L L + +N + E
Sbjct: 246 PADAFRGL-RRLRTLNLGGN--ALDRVA-------RAWFADLAELELLYLDRNSIAFVEE 295
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
+LS L L ++ N+L L+ Q + + L +N W
Sbjct: 296 GAFQNLSG----------------LLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWC 339
Query: 435 CDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSF 477
CD C + +M + + + C SP + G ++F
Sbjct: 340 CD-CRLEWLRDWMEG---SGRVTDVPCASPGSVAGLDLSQVTF 378
Score = 44.4 bits (100), Expect = 0.001
Identities = 32/89 (35%), Positives = 43/89 (48%)
Query: 102 SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLI 161
+F GL+ LR LNL N L V F L L L+LD N I + F++L+ L L
Sbjct: 249 AFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALH 308
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNP 190
L N+++ L F+ L L L NP
Sbjct: 309 LNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
>BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 63/248 (25%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN--FRGLINLTELHLDH 140
+++++L++ + + ++ SF +L+ +NL+HN + S D F L NL +LHL+H
Sbjct: 91 MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEV 198
N++E+ F SL+ L+L N+IS L + L L++LDL N L D L ++
Sbjct: 151 NNLEEF---PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F ++ ++ + C R+ + L L L L N + F L +L L++
Sbjct: 208 FAKME--KLMQLNLC-SNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
N+L I N+F + L++ N+ + +N+I++ +L
Sbjct: 265 SHNKLQDIPYNIFNLPNIVE-LSVGHNKLKQAFYIPRNLEHLY----LQNNEIEKMNLTV 319
Query: 319 FAPVVDSL 326
P +D L
Sbjct: 320 MCPSIDPL 327
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A NL +LH+ ++N+ +F F ++L L L +N ++ + + GL+NLT L L
Sbjct: 138 AKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 140 HNHIEQ--MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
+N++ + + F + L L L +N++ ++ L + L L L +N ++ + +
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEK 251
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + L + L+ I I++L P + EL +G N K F + L+ L
Sbjct: 252 YFDKLPKLHTLRMSHNKLQDIPYNIFNL-PNIVELSVGHNKLK----QAFYIPRNLEHLY 306
Query: 258 LDGNQL 263
L N++
Sbjct: 307 LQNNEI 312
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 229 LEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+E++L N K D F L L +L L+ N L + F + L L L N
Sbjct: 117 LKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNE 173
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKI-DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVL 345
D+ +N + D ++ L +N N L +
Sbjct: 174 ISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS 233
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
++ + L N S+ IP+ +F L L +S NKL P+ + + ++ L +
Sbjct: 234 SLMY----LSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVE-LSVG 288
Query: 406 HNKLQ 410
HNKL+
Sbjct: 289 HNKLK 293
>AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein.
Length = 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 63/248 (25%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN--FRGLINLTELHLDH 140
+++++L++ + + ++ SF +L+ +NL+HN + S D F L NL +LHL+H
Sbjct: 91 MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEV 198
N++E+ F SL+ L+L N+IS L + L L++LDL N L D L ++
Sbjct: 151 NNLEEF---PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F ++ ++ + C R+ + L L L L N + F L +L L++
Sbjct: 208 FAKME--KLMQLNLC-SNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
N+L I N+F + L++ N+ + +N+I++ +L
Sbjct: 265 SHNKLQDIPYNIFNLPNIVE-LSVGHNKLKQAFYIPRNLEHLY----LQNNEIEKMNLTV 319
Query: 319 FAPVVDSL 326
P +D L
Sbjct: 320 MCPSIDPL 327
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A NL +LH+ ++N+ +F F ++L L L +N ++ + + GL+NLT L L
Sbjct: 138 AKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 140 HNHIEQ--MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
+N++ + + F + L L L +N++ ++ L + L L L +N ++ + +
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEK 251
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + L + L+ I I++L P + EL +G N K F + L+ L
Sbjct: 252 YFDKLPKLHTLRMSHNKLQDIPYNIFNL-PNIVELSVGHNKLK----QAFYIPRNLEHLY 306
Query: 258 LDGNQL 263
L N++
Sbjct: 307 LQNNEI 312
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 229 LEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+E++L N K D F L L +L L+ N L + F + L L L N
Sbjct: 117 LKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNE 173
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKI-DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVL 345
D+ +N + D ++ L +N N L +
Sbjct: 174 ISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS 233
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
++ + L N S+ IP+ +F L L +S NKL P+ + + ++ L +
Sbjct: 234 SLMY----LSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVE-LSVG 288
Query: 406 HNKLQ 410
HNKL+
Sbjct: 289 HNKLK 293
>AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 63/248 (25%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN--FRGLINLTELHLDH 140
+++++L++ + + ++ SF +L+ +NL+HN + S D F L NL +LHL+H
Sbjct: 91 MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEV 198
N++E+ F SL+ L+L N+IS L + L L++LDL N L D L ++
Sbjct: 151 NNLEEF---PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F ++ ++ + C R+ + L L L L N + F L +L L++
Sbjct: 208 FAKME--KLMQLNLC-SNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
N+L I N+F + L++ N+ + +N+I++ +L
Sbjct: 265 SHNKLQDIPYNIFNLPNIVE-LSVGHNKLKQAFYIPRNLEHLY----LQNNEIEKMNLTV 319
Query: 319 FAPVVDSL 326
P +D L
Sbjct: 320 MCPSIDPL 327
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A NL +LH+ ++N+ +F F ++L L L +N ++ + + GL+NLT L L
Sbjct: 138 AKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 140 HNHIEQ--MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
+N++ + + F + L L L +N++ ++ L + L L L +N ++ + +
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEK 251
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + L + L+ I I++L P + EL +G N K F + L+ L
Sbjct: 252 YFDKLPKLHTLRMSHNKLQDIPYNIFNL-PNIVELSVGHNKLK----QAFYIPRNLEHLY 306
Query: 258 LDGNQL 263
L N++
Sbjct: 307 LQNNEI 312
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 229 LEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+E++L N K D F L L +L L+ N L + F + L L L N
Sbjct: 117 LKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNE 173
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKI-DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVL 345
D+ +N + D ++ L +N N L +
Sbjct: 174 ISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS 233
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
++ + L N S+ IP+ +F L L +S NKL P+ + + ++ L +
Sbjct: 234 SLMY----LSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVE-LSVG 288
Query: 406 HNKLQ 410
HNKL+
Sbjct: 289 HNKLK 293
>AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein.
Length = 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 63/248 (25%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN--FRGLINLTELHLDH 140
+++++L++ + + ++ SF +L+ +NL+HN + S D F L NL +LHL+H
Sbjct: 91 MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEV 198
N++E+ F SL+ L+L N+IS L + L L++LDL N L D L ++
Sbjct: 151 NNLEEF---PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F ++ ++ + C R+ + L L L L N + F L +L L++
Sbjct: 208 FAKME--KLMQLNLC-SNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
N+L I N+F + L++ N+ + +N+I++ +L
Sbjct: 265 SHNKLQDIPYNIFNLPNIVE-LSVGHNKLKQAFYIPRNLEHLY----LQNNEIEKMNLTV 319
Query: 319 FAPVVDSL 326
P +D L
Sbjct: 320 MCPSIDPL 327
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A NL +LH+ ++N+ +F F ++L L L +N ++ + + GL+NLT L L
Sbjct: 138 AKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 140 HNHIEQ--MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
+N++ + + F + L L L +N++ ++ L + L L L +N ++ + +
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEK 251
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + L + L+ I I++L P + EL +G N K F + L+ L
Sbjct: 252 YFDKLPKLHTLRMSHNKLQDIPYNIFNL-PNIVELSVGHNKLK----QAFYIPRNLEHLY 306
Query: 258 LDGNQL 263
L N++
Sbjct: 307 LQNNEI 312
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 229 LEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+E++L N K D F L L +L L+ N L + F + L L L N
Sbjct: 117 LKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNE 173
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKI-DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVL 345
D+ +N + D ++ L +N N L +
Sbjct: 174 ISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS 233
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
++ + L N S+ IP+ +F L L +S NKL P+ + + ++ L +
Sbjct: 234 SLMY----LSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVE-LSVG 288
Query: 406 HNKLQ 410
HNKL+
Sbjct: 289 HNKLK 293
>AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 71.7 bits (168), Expect = 6e-12
Identities = 63/248 (25%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADN--FRGLINLTELHLDH 140
+++++L++ + + ++ SF +L+ +NL+HN + S D F L NL +LHL+H
Sbjct: 91 MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD--LNPEV 198
N++E+ F SL+ L+L N+IS L + L L++LDL N L D L ++
Sbjct: 151 NNLEEF---PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
Query: 199 FKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
F ++ ++ + C R+ + L L L L N + F L +L L++
Sbjct: 208 FAKME--KLMQLNLC-SNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 259 DGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQT 318
N+L I N+F + L++ N+ + +N+I++ +L
Sbjct: 265 SHNKLQDIPYNIFNLPNIVE-LSVGHNKLKQAFYIPRNLEHLY----LQNNEIEKMNLTV 319
Query: 319 FAPVVDSL 326
P +D L
Sbjct: 320 MCPSIDPL 327
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A NL +LH+ ++N+ +F F ++L L L +N ++ + + GL+NLT L L
Sbjct: 138 AKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 140 HNHIEQ--MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
+N++ + + F + L L L +N++ ++ L + L L L +N ++ + +
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEK 251
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
F + L + L+ I I++L P + EL +G N K F + L+ L
Sbjct: 252 YFDKLPKLHTLRMSHNKLQDIPYNIFNL-PNIVELSVGHNKLK----QAFYIPRNLEHLY 306
Query: 258 LDGNQL 263
L N++
Sbjct: 307 LQNNEI 312
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 229 LEELDLGENLFKYLTSDE--FISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L+E++L N K D F L L +L L+ N L + F + L L L N
Sbjct: 117 LKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE---EFPFPLPKSLERLLLGYNE 173
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKI-DRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVL 345
D+ +N + D ++ L +N N L +
Sbjct: 174 ISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS 233
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
++ + L N S+ IP+ +F L L +S NKL P+ + + ++ L +
Sbjct: 234 SLMY----LSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVE-LSVG 288
Query: 406 HNKLQ 410
HNKL+
Sbjct: 289 HNKLK 293
>BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein.
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 70.9 bits (166), Expect = 1e-11
Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 12/260 (4%)
Query: 16 CPDECTCTMT--FDLEEGH--TTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLT 71
CP C C + F + + T V C + IP + + D V+++ +
Sbjct: 32 CPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSN-LSSDTQVLLLQSN-------N 83
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
I + NL EL +N +I + L L L+L N +T + + L
Sbjct: 84 IAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLS 143
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
NL EL+++HN I +S+ F L +L L L +N++ + SR F L IL + +NP+
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
+ FK + +LR L I + LE L +N + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 252 RLKKLKLDGNQLSVIVDNMF 271
LK L L+ N + I + F
Sbjct: 264 NLKFLDLNKNPIHKIQEGDF 283
Score = 62.5 bits (145), Expect = 4e-09
Identities = 53/205 (25%), Positives = 96/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+EL+I ++ + +I +F GL+NL L+L N L + + F NL L + N +
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F+ L +L++L+LA ++ + L L L DN L + + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI--SLKRLKKLKLDGN 261
+L+ + + +I + + RL+EL + N+ + ++ D + +L L KL+ N
Sbjct: 264 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGI-NNMGELVSVDRYALDNLPELTKLEATNN 322
Query: 262 -QLSVIVDNMFGRNRELHVLTLSRN 285
+LS I F L L L+ N
Sbjct: 323 PKLSYIHRLAFRSVPALESLMLNNN 347
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 2/200 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L ELD +N F + +L +L L L+ NQ++ + D L L ++ N+
Sbjct: 97 LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQIS 156
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
++ NK+ + F + I G N + + + + L
Sbjct: 157 TISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNL--EILMIGENPVIGILDMNFKPL 214
Query: 349 PEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
+ + LA + L +IP N + L +L NKL + P L K L+ LD++ N
Sbjct: 215 ANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNP 274
Query: 409 LQTLSEQDLQRLEAIAEVNL 428
+ + E D + + + E+ +
Sbjct: 275 IHKIQEGDFKNMLRLKELGI 294
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTH-NNLTSVVADNFRGLINLTELHLDHN- 141
NL+ L + + + I + F + L+ L + + L SV L LT+L +N
Sbjct: 264 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNP 323
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR + +L++L+L NN ++ + + L L + + NPL
Sbjct: 324 KLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/190 (32%), Positives = 98/190 (51%), Gaps = 6/190 (3%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
VNL+ L +++ ++ I S + L NL L+L NNL +V +F+ L NL+ L L HN+
Sbjct: 585 VNLKSLELISCDLERIPH-SIFSLNNLHELDLRENNLKTVEEISFQHLQNLSCLKLWHNN 643
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
I + ++ L++L+ L L +N I L +LF + KL LDLS N LT + PE + +
Sbjct: 644 IAYIPAQ-IGALSNLEQLSLDHNNIENLPLQLF-LCTKLHYLDLSYNHLTFI-PEEIQYL 700
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+L+ F + + ++ +L+ L LG+N L S L L L+L GN
Sbjct: 701 SNLQYFAVTNNNIEMLPDGLFQ-CKKLQCLLLGKNSLMNL-SPHVGELSNLTHLELIGNY 758
Query: 263 LSVIVDNMFG 272
L + + G
Sbjct: 759 LETLPPELEG 768
Score = 38.7 bits (86), Expect = 0.054
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 343 IVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRL 402
+V +LP + + L N + + N +L +L+L L R P + S L L
Sbjct: 555 VVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNN-LHEL 613
Query: 403 DISHNKLQTLSEQDLQRLEAIAEVNLMKNN 432
D+ N L+T+ E Q L+ ++ + L NN
Sbjct: 614 DLRENNLKTVEEISFQHLQNLSCLKLWHNN 643
>AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ90428 fis, clone NT2RP3000616, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens
cDNA FLJ90402 fis, clone NT2RP2006004, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 627
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ14788 fis, clone NT2RP4000925, weakly similar to
FIBROMODULIN PRECURSOR. ).
Length = 623
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 80 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 139
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 140 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 195
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 196 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 253
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 254 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 312
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 313 KVRGMAIKDLNAELFD 328
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 50 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 109
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 110 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 166
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 167 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 224
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 225 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 255
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 186 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 243
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 244 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 280
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 151 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 210
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 211 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 268
Query: 203 QHL 205
++
Sbjct: 269 DNI 271
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 209 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 265
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 266 DDLDNITQLILRNN 279
>AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ14391 fis, clone HEMBA1003077, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat
transmembrane protein FLRT3 protein.
Length = 649
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 221
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 279
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 280 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 338
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 339 KVRGMAIKDLNAELFD 354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 76 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 135
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 136 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 192
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 193 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 250
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 251 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 212 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 269
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 270 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 177 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 236
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 237 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294
Query: 203 QHL 205
++
Sbjct: 295 DNI 297
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 235 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 291
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 292 DDLDNITQLILRNN 305
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 70.9 bits (166), Expect = 1e-11
Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 12/260 (4%)
Query: 16 CPDECTCTMT--FDLEEGH--TTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLT 71
CP C C + F + + T V C + IP + + D V+++ +
Sbjct: 32 CPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSN-LSSDTQVLLLQSN-------N 83
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
I + NL EL +N +I + L L L+L N +T + + L
Sbjct: 84 IAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLS 143
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
NL EL+++HN I +S+ F L +L L L +N++ + SR F L IL + +NP+
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
+ FK + +LR L I + LE L +N + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 252 RLKKLKLDGNQLSVIVDNMF 271
LK L L+ N + I + F
Sbjct: 264 NLKFLDLNKNPIHKIQEGDF 283
Score = 62.5 bits (145), Expect = 4e-09
Identities = 53/205 (25%), Positives = 96/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+EL+I ++ + +I +F GL+NL L+L N L + + F NL L + N +
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F+ L +L++L+LA ++ + L L L DN L + + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI--SLKRLKKLKLDGN 261
+L+ + + +I + + RL+EL + N+ + ++ D + +L L KL+ N
Sbjct: 264 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGI-NNMGELVSVDRYALDNLPELTKLEATNN 322
Query: 262 -QLSVIVDNMFGRNRELHVLTLSRN 285
+LS I F L L L+ N
Sbjct: 323 PKLSYIHRLAFRSVPALESLMLNNN 347
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 2/200 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L ELD +N F + +L +L L L+ NQ++ + D L L ++ N+
Sbjct: 97 LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQIS 156
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
++ NK+ + F + I G N + + + + L
Sbjct: 157 TISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNL--EILMIGENPVIGILDMNFKPL 214
Query: 349 PEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
+ + LA + L +IP N + L +L NKL + P L K L+ LD++ N
Sbjct: 215 ANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNP 274
Query: 409 LQTLSEQDLQRLEAIAEVNL 428
+ + E D + + + E+ +
Sbjct: 275 IHKIQEGDFKNMLRLKELGI 294
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTH-NNLTSVVADNFRGLINLTELHLDHN- 141
NL+ L + + + I + F + L+ L + + L SV L LT+L +N
Sbjct: 264 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNP 323
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR + +L++L+L NN ++ + + L L + + NPL
Sbjct: 324 KLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 70.9 bits (166), Expect = 1e-11
Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 12/260 (4%)
Query: 16 CPDECTCTMT--FDLEEGH--TTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLT 71
CP C C + F + + T V C + IP + + D V+++ +
Sbjct: 46 CPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSN-LSSDTQVLLLQSN-------N 97
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
I + NL EL +N +I + L L L+L N +T + + L
Sbjct: 98 IAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLS 157
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
NL EL+++HN I +S+ F L +L L L +N++ + SR F L IL + +NP+
Sbjct: 158 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 217
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
+ FK + +LR L I + LE L +N + +
Sbjct: 218 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 277
Query: 252 RLKKLKLDGNQLSVIVDNMF 271
LK L L+ N + I + F
Sbjct: 278 NLKFLDLNKNPIHKIQEGDF 297
Score = 62.5 bits (145), Expect = 4e-09
Identities = 53/205 (25%), Positives = 96/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+EL+I ++ + +I +F GL+NL L+L N L + + F NL L + N +
Sbjct: 158 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 217
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F+ L +L++L+LA ++ + L L L DN L + + +
Sbjct: 218 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 277
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI--SLKRLKKLKLDGN 261
+L+ + + +I + + RL+EL + N+ + ++ D + +L L KL+ N
Sbjct: 278 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGI-NNMGELVSVDRYALDNLPELTKLEATNN 336
Query: 262 -QLSVIVDNMFGRNRELHVLTLSRN 285
+LS I F L L L+ N
Sbjct: 337 PKLSYIHRLAFRSVPALESLMLNNN 361
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 2/200 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L ELD +N F + +L +L L L+ NQ++ + D L L ++ N+
Sbjct: 111 LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQIS 170
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
++ NK+ + F + I G N + + + + L
Sbjct: 171 TISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNL--EILMIGENPVIGILDMNFKPL 228
Query: 349 PEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
+ + LA + L +IP N + L +L NKL + P L K L+ LD++ N
Sbjct: 229 ANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNP 288
Query: 409 LQTLSEQDLQRLEAIAEVNL 428
+ + E D + + + E+ +
Sbjct: 289 IHKIQEGDFKNMLRLKELGI 308
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTH-NNLTSVVADNFRGLINLTELHLDHN- 141
NL+ L + + + I + F + L+ L + + L SV L LT+L +N
Sbjct: 278 NLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNP 337
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR + +L++L+L NN ++ + + L L + + NPL
Sbjct: 338 KLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 387
>AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein.
Length = 662
Score = 70.9 bits (166), Expect = 1e-11
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 10/256 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSV--IVDNMFGRNRELHVLTLSRNR 286
++EL L EN + +T D + L++L LD N +S I + F + L +L LSRN
Sbjct: 119 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 178
Query: 287 XXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAI-VL 345
D + I LQ SLK + GN L + + V
Sbjct: 179 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLT----SLKRLVLDGNLLNNHGLGDKVF 234
Query: 346 QILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDIS 405
L + + L SL P N N L L L N ++R P S + L RLD+S
Sbjct: 235 FNLVNLTELSLVRNSLTAAPVNLPGTN--LRKLYLQDNHINRVPPNAFSYLRQLYRLDMS 292
Query: 406 HNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPL 465
+N L L + L+ I ++ L N W+C C + ++ + + +R L C +P
Sbjct: 293 NNNLSNLPQGIFDDLDNITQLILRNNPWYCG-CKMKWVRDWLQSLPVKVNVRGLMCQAPE 351
Query: 466 RLRGATFGSLSFEQLD 481
++RG L+ E D
Sbjct: 352 KVRGMAIKDLNAELFD 367
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 79 PAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL 138
P+ NL ++ + S+ +F + ++ L+L NN+ ++ D+ + L ELHL
Sbjct: 89 PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHL 148
Query: 139 DHNHIEQMSSE--TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP 196
D N + +S E FR L+ L L+ N +ST+ L R + +L L DN ++ ++
Sbjct: 149 DDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR---LDDNRISTISS 205
Query: 197 EVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+ + L+ LL + +++ + L EL L N + + L+
Sbjct: 206 PSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRN--SLTAAPVNLPGTNLR 263
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
KL L N ++ + N F R+L+ L +S N
Sbjct: 264 KLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 294
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 94 NVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRH 153
N +G F+ L NL L+L N+LT+ N G NL +L+L NHI ++ F +
Sbjct: 225 NNHGLGDKVFFNLVNLTELSLVRNSLTAAPV-NLPGT-NLRKLYLQDNHINRVPPNAFSY 282
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
L L L ++NN +S L +F L ++ L L +NP
Sbjct: 283 LRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 319
Score = 50.8 bits (116), Expect = 1e-05
Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-VADN-FRGLINLTELHLDHNH 142
+ EL + ++ + +I S GL +L+ L L N L + + D F L+NLTEL L N
Sbjct: 190 IEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNS 249
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ ++ T+L+ L L +N I+ + F L +L LD+S+N L++L +F D+
Sbjct: 250 LT--AAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 307
Query: 203 QHL 205
++
Sbjct: 308 DNI 310
Score = 38.3 bits (85), Expect = 0.071
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Query: 68 NFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNF 127
N LT P+ P NLR+L++ ++++ + +F L+ L L++++NNL+++ F
Sbjct: 248 NSLTAAPV---NLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIF 304
Query: 128 RGLINLTELHLDHN 141
L N+T+L L +N
Sbjct: 305 DDLDNITQLILRNN 318
>BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
+L ++N+ + + F GL N ++L NN+ + F GL L +LH++HN +E +
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
+TF L +L+ L NN I+ + F L +L +L L+DN + L P +F+
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFR 181
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 60 IAAPPDRP---NFLTIGPIFTQPAPF---VNLRELHIVNSNVPSIGQFSFWGLQNLRVLN 113
I+ PP RP + L G F N +H+ +N+ I +F GL L+ L+
Sbjct: 59 ISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLH 118
Query: 114 LTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
+ HN+L + D F GL NL L D+N I + F L LK LIL +N I +L
Sbjct: 119 INHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN 178
Query: 174 LFRMLAKLSILDLSDNPLTDL 194
+FR + L+ LDL N L L
Sbjct: 179 IFRFV-PLTHLDLRGNQLQTL 198
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N LT + ++F GL N +HL N+I + F L LK L + +N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L +N +T + P F + L++ + + I+ VP L
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTH 187
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGNQ 262
LDL N + L F+ + R+ L+L+ N+
Sbjct: 188 LDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L LH+ N+ + + + SF L L+ L L N+LT + F GL NL L+L++N
Sbjct: 386 YFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 445
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
I+++ TF + LK L L NN + L +F + L+ ++L N T L
Sbjct: 446 AIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGV-PLTKVNLKTNQFTHL 497
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNE--------HLVALDLSWNKLSRFPFKLLSKT 396
L+IL E GL NL + NF T E L L L+ N + P +
Sbjct: 124 LEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV 183
Query: 397 KFLQRLDISHNKLQTLSEQD-LQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNST 455
L LD+ N+LQTL L+ + I ++ L N W C+ C + ++ S
Sbjct: 184 P-LTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACN-CDLLQLKTWLENMPPQSI 241
Query: 456 IRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
I + C+SP +G+ L E + P P +E
Sbjct: 242 IGDVVCNSPPFFKGSILSRLKKESICPTPPVYE 274
Score = 40.7 bits (91), Expect = 0.013
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
LE L LG N + L F++L RL+KL L+GN L+ + MF L L L N
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVD-SLKTINFSGNNLPLNEIAIVL 345
+++N + H+ + P+ +LKT F+ +LP++ I L
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFT--HLPVSNILDDL 506
Query: 346 QILPEI 351
+L +I
Sbjct: 507 DLLTQI 512
Score = 38.7 bits (86), Expect = 0.054
Identities = 28/112 (25%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NN ++ L + F L + L N + D+ F + L+ L +
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+H + LE L N + F L RLK L L+ N + + N+F
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 180
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 47/102 (46%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L +N LT L+ F + + + I ++ + L++L + N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
D F L+ L+ L+ D N ++VI + F + L VL L+ N
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
>BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
+L ++N+ + + F GL N ++L NN+ + F GL L +LH++HN +E +
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
+TF L +L+ L NN I+ + F L +L +L L+DN + L P +F+
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFR 181
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 60 IAAPPDRP---NFLTIGPIFTQPAPF---VNLRELHIVNSNVPSIGQFSFWGLQNLRVLN 113
I+ PP RP + L G F N +H+ +N+ I +F GL L+ L+
Sbjct: 59 ISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLH 118
Query: 114 LTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
+ HN+L + D F GL NL L D+N I + F L LK LIL +N I +L
Sbjct: 119 INHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN 178
Query: 174 LFRMLAKLSILDLSDNPLTDL 194
+FR + L+ LDL N L L
Sbjct: 179 IFRFV-PLTHLDLRGNQLQTL 198
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N LT + ++F GL N +HL N+I + F L LK L + +N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L +N +T + P F + L++ + + I+ VP L
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTH 187
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGNQ 262
LDL N + L F+ + R+ L+L+ N+
Sbjct: 188 LDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L LH+ N+ + + + SF L L+ L L N+LT + F GL NL L+L++N
Sbjct: 386 YFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 445
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
I+++ TF + LK L L NN + L +F + L+ ++L N T L
Sbjct: 446 AIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGV-PLTKVNLKTNQFTHL 497
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNE--------HLVALDLSWNKLSRFPFKLLSKT 396
L+IL E GL NL + NF T E L L L+ N + P +
Sbjct: 124 LEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV 183
Query: 397 KFLQRLDISHNKLQTLSEQD-LQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNST 455
L LD+ N+LQTL L+ + I ++ L N W C+ C + ++ S
Sbjct: 184 P-LTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACN-CDLLQLKTWLENMPPQSI 241
Query: 456 IRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
I + C+SP +G+ L E + P P +E
Sbjct: 242 IGDVVCNSPPFFKGSILSRLKKESICPTPPVYE 274
Score = 40.7 bits (91), Expect = 0.013
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
LE L LG N + L F++L RL+KL L+GN L+ + MF L L L N
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVD-SLKTINFSGNNLPLNEIAIVL 345
+++N + H+ + P+ +LKT F+ +LP++ I L
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFT--HLPVSNILDDL 506
Query: 346 QILPEI 351
+L +I
Sbjct: 507 DLLTQI 512
Score = 38.7 bits (86), Expect = 0.054
Identities = 28/112 (25%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NN ++ L + F L + L N + D+ F + L+ L +
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+H + LE L N + F L RLK L L+ N + + N+F
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 180
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 47/102 (46%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L +N LT L+ F + + + I ++ + L++L + N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
D F L+ L+ L+ D N ++VI + F + L VL L+ N
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
>BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
+L ++N+ + + F GL N ++L NN+ + F GL L +LH++HN +E +
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
+TF L +L+ L NN I+ + F L +L +L L+DN + L P +F+
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFR 181
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 60 IAAPPDRP---NFLTIGPIFTQPAPF---VNLRELHIVNSNVPSIGQFSFWGLQNLRVLN 113
I+ PP RP + L G F N +H+ +N+ I +F GL L+ L+
Sbjct: 59 ISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLH 118
Query: 114 LTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
+ HN+L + D F GL NL L D+N I + F L LK LIL +N I +L
Sbjct: 119 INHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN 178
Query: 174 LFRMLAKLSILDLSDNPLTDL 194
+FR + L+ LDL N L L
Sbjct: 179 IFRFV-PLTHLDLRGNQLQTL 198
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N LT + ++F GL N +HL N+I + F L LK L + +N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L +N +T + P F + L++ + + I+ VP L
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTH 187
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGNQ 262
LDL N + L F+ + R+ L+L+ N+
Sbjct: 188 LDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L LH+ N+ + + + SF L L+ L L N+LT + F GL NL L+L++N
Sbjct: 386 YFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 445
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
I+++ TF + LK L L NN + L +F + L+ ++L N T L
Sbjct: 446 AIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGV-PLTKVNLKTNQFTHL 497
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNE--------HLVALDLSWNKLSRFPFKLLSKT 396
L+IL E GL NL + NF T E L L L+ N + P +
Sbjct: 124 LEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV 183
Query: 397 KFLQRLDISHNKLQTLSEQD-LQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNST 455
L LD+ N+LQTL L+ + I ++ L N W C+ C + ++ S
Sbjct: 184 P-LTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACN-CDLLQLKTWLENMPPQSI 241
Query: 456 IRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
I + C+SP +G+ L E + P P +E
Sbjct: 242 IGDVVCNSPPFFKGSILSRLKKESICPTPPVYE 274
Score = 40.7 bits (91), Expect = 0.013
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
LE L LG N + L F++L RL+KL L+GN L+ + MF L L L N
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVD-SLKTINFSGNNLPLNEIAIVL 345
+++N + H+ + P+ +LKT F+ +LP++ I L
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFT--HLPVSNILDDL 506
Query: 346 QILPEI 351
+L +I
Sbjct: 507 DLLTQI 512
Score = 38.7 bits (86), Expect = 0.054
Identities = 28/112 (25%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NN ++ L + F L + L N + D+ F + L+ L +
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+H + LE L N + F L RLK L L+ N + + N+F
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 180
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 47/102 (46%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L +N LT L+ F + + + I ++ + L++L + N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
D F L+ L+ L+ D N ++VI + F + L VL L+ N
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
>BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
+L ++N+ + + F GL N ++L NN+ + F GL L +LH++HN +E +
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
+TF L +L+ L NN I+ + F L +L +L L+DN + L P +F+
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFR 181
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 60 IAAPPDRP---NFLTIGPIFTQPAPF---VNLRELHIVNSNVPSIGQFSFWGLQNLRVLN 113
I+ PP RP + L G F N +H+ +N+ I +F GL L+ L+
Sbjct: 59 ISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLH 118
Query: 114 LTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
+ HN+L + D F GL NL L D+N I + F L LK LIL +N I +L
Sbjct: 119 INHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN 178
Query: 174 LFRMLAKLSILDLSDNPLTDL 194
+FR + L+ LDL N L L
Sbjct: 179 IFRFV-PLTHLDLRGNQLQTL 198
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N LT + ++F GL N +HL N+I + F L LK L + +N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L +N +T + P F + L++ + + I+ VP L
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTH 187
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGNQ 262
LDL N + L F+ + R+ L+L+ N+
Sbjct: 188 LDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L LH+ N+ + + + SF L L+ L L N+LT + F GL NL L+L++N
Sbjct: 386 YFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 445
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
I+++ TF + LK L L NN + L +F + L+ ++L N T L
Sbjct: 446 AIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGV-PLTKVNLKTNQFTHL 497
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNE--------HLVALDLSWNKLSRFPFKLLSKT 396
L+IL E GL NL + NF T E L L L+ N + P +
Sbjct: 124 LEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV 183
Query: 397 KFLQRLDISHNKLQTLSEQD-LQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNST 455
L LD+ N+LQTL L+ + I ++ L N W C+ C + ++ S
Sbjct: 184 P-LTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACN-CDLLQLKTWLENMPPQSI 241
Query: 456 IRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
I + C+SP +G+ L E + P P +E
Sbjct: 242 IGDVVCNSPPFFKGSILSRLKKESICPTPPVYE 274
Score = 40.7 bits (91), Expect = 0.013
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
LE L LG N + L F++L RL+KL L+GN L+ + MF L L L N
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRF--HLQTFAPVVD-SLKTINFSGNNLPLNEIAIVL 345
+++N + H+ + P+ +LKT F+ +LP++ I L
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFT--HLPVSNILDDL 506
Query: 346 QILPEI 351
+L +I
Sbjct: 507 DLLTQI 512
Score = 38.7 bits (86), Expect = 0.054
Identities = 28/112 (25%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NN ++ L + F L + L N + D+ F + L+ L +
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+H + LE L N + F L RLK L L+ N + + N+F
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 180
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 47/102 (46%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L +N LT L+ F + + + I ++ + L++L + N + L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
D F L+ L+ L+ D N ++VI + F + L VL L+ N
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
>BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 70.5 bits (165), Expect = 1e-11
Identities = 38/119 (31%), Positives = 72/119 (60%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N++EL + ++ + SI + F +NL +L+L +NN+ +V ++F+ L++L L++D N++
Sbjct: 376 NVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNSFKNLLDLRWLYMDSNYL 435
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S E F L +L+ L + N I ++ F + KL IL L++N L L +VF +
Sbjct: 436 DTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV 494
Score = 62.1 bits (144), Expect = 5e-09
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N+LT + + F N LH+++N + ++ F L +K L + NN+I +
Sbjct: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L L N L D++P F+D+ L + L+ + ++ VP +
Sbjct: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 181
Query: 232 LDLGENLFKYLTSDEFI-SLKRLKKLKLDGN 261
LDL N K L +E + + + ++ L+ N
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
Score = 62.1 bits (144), Expect = 5e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N NV S+ L N++ L L N + S+ +F NL L L +N+I + + +F
Sbjct: 361 NRNVSSLADLKP-KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNSF 419
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
++L L+ L + +N + TL F L L L++ N + + P F + LRI
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
LLR + ++ V L +L L N F YL + L + ++ L GN
Sbjct: 480 NNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F N LH+ N+ + I +F GLQ ++ L++ +N + S F GL +L L D
Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
N + + F+ L L+ LIL +N ISTL + +F+ + ++ LDL N L L
Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITHLDLRGNRLKTL 192
Score = 55.6 bits (128), Expect = 4e-07
Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + N+N+ ++ SF L +LR L + N L ++ + F GL NL L++++N
Sbjct: 398 YKNLILLDLGNNNIATVENNSFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
I+ + TF + L+ LIL NN + +L +F ++ LS L L +N
Sbjct: 458 AIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS-LSKLSLHNN 504
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L + +++ + F N L++ +N L +V F GL + LH++
Sbjct: 55 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 114
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+N I+ +TF L L+ L N + + F+ L KL +L L+DN ++ L VF
Sbjct: 115 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ I HL + R L ++ +P + E+ L +N
Sbjct: 175 QYVPITHLDLRGNR--LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS-EQDLQR 419
L++I F L L L+ N +S P + + LD+ N+L+TL E+ L++
Sbjct: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQ 200
Query: 420 LEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQ 479
+ IAE+ L N W C C ++ ++ N+ I + C +P RL+G + EQ
Sbjct: 201 IPGIAEILLEDNPWDC-TCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETT-EQ 258
Query: 480 LDPCPTTHEAQMSVIA 495
D CP + S+ A
Sbjct: 259 -DLCPLKNRVDSSLPA 273
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
++LR L++ ++ + ++ + F GLQNL LN+ +N + ++ F + L L L++N
Sbjct: 423 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 482
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + + F + SL L L NN L V+ + L + +DL NP
Sbjct: 483 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 38.3 bits (85), Expect = 0.071
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
L++++ L L +N+I ++ F L +LDL +N + + FK++ LR
Sbjct: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNSFKNLLDLRWLYMDSN 433
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L ++ + + + LE L++ N + + F ++ +L+ L L+ N L + ++F
Sbjct: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA- 492
Query: 274 NRELHVLTLSRN 285
L L+L N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 37.9 bits (84), Expect = 0.094
Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
N +S+L L L+ + L L DN + + F D ++L + + + +
Sbjct: 361 NRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNSF 419
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ L L + N L+ ++F L+ L+ L ++ N + +I+ F +L +L L+
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 284 RN 285
N
Sbjct: 480 NN 481
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 70.5 bits (165), Expect = 1e-11
Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 12/260 (4%)
Query: 16 CPDECTCTMT--FDLEEGH--TTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLT 71
CP C C + F + + T V C + IP + + D V+++ +
Sbjct: 32 CPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSN-LSSDTQVLLLQSN-------N 83
Query: 72 IGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLI 131
I + NL EL +N +I + L L L+L N +T + + L
Sbjct: 84 IAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLS 143
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
NL EL+++HN I +S+ F L +L L L +N++ + SR F L IL + +NP+
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
+ FK + +LR L I + LE L +N + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 252 RLKKLKLDGNQLSVIVDNMF 271
LK L L+ N + I + F
Sbjct: 264 SLKFLDLNKNPIHKIQEGDF 283
Score = 61.7 bits (143), Expect = 7e-09
Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+EL+I ++ + +I +F GL+NL L+L N L + + F NL L + N +
Sbjct: 144 NLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPV 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F+ L +L++L+LA ++ + L L L DN L + + +
Sbjct: 204 IGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVP 263
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFI--SLKRLKKLKLDGN 261
L+ + + +I + + RL+EL + N+ + ++ D + +L L KL+ N
Sbjct: 264 SLKFLDLNKNPIHKIQEGDFKNMLRLKELGI-NNMGELVSVDRYALDNLPELTKLEATNN 322
Query: 262 -QLSVIVDNMFGRNRELHVLTLSRN 285
+LS I F L L L+ N
Sbjct: 323 PKLSYIHRLAFRSVPALESLMLNNN 347
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 2/200 (1%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L ELD +N F + +L +L L L+ NQ++ + D L L ++ N+
Sbjct: 97 LTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQIS 156
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
++ NK+ + F + I G N + + + + L
Sbjct: 157 TISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNL--EILMIGENPVIGILDMNFKPL 214
Query: 349 PEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNK 408
+ + LA + L +IP N + L +L NKL + P L K L+ LD++ N
Sbjct: 215 ANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNP 274
Query: 409 LQTLSEQDLQRLEAIAEVNL 428
+ + E D + + + E+ +
Sbjct: 275 IHKIQEGDFKNMLRLKELGI 294
Score = 35.1 bits (77), Expect = 0.66
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTH-NNLTSVVADNFRGLINLTELHLDHN- 141
+L+ L + + + I + F + L+ L + + L SV L LT+L +N
Sbjct: 264 SLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNP 323
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR + +L++L+L NN ++ + + L L + + NPL
Sbjct: 324 KLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
Score = 31.9 bits (69), Expect = 6.2
Identities = 41/192 (21%), Positives = 74/192 (38%), Gaps = 2/192 (1%)
Query: 243 TSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXX 302
T DE L L +L N + I + +L L L N+
Sbjct: 87 TVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQ 146
Query: 303 XXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQ 362
I+HN+I FA + + L+ ++ + N L + + + P + + + +
Sbjct: 147 ELYINHNQISTISAHAFAGLKNLLR-LHLNSNKLKVID-SRWFDSTPNLEILMIGENPVI 204
Query: 363 EIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEA 422
I F +L +L L+ L+ P L L+ L NKL + + LQ++ +
Sbjct: 205 GILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPS 264
Query: 423 IAEVNLMKNNWH 434
+ ++L KN H
Sbjct: 265 LKFLDLNKNPIH 276
>AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22774 fis, clone KAIA1575. ).
Length = 440
Score = 70.5 bits (165), Expect = 1e-11
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 87 ELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQM 146
+L ++N+ + + F GL N ++L NN+ + F GL L +LH++HN +E +
Sbjct: 25 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 84
Query: 147 SSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
+TF L +L+ L NN I+ + F L +L +L L+DN + L P +F+
Sbjct: 85 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFR 138
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 60 IAAPPDRP---NFLTIGPIFTQPAPF---VNLRELHIVNSNVPSIGQFSFWGLQNLRVLN 113
I+ PP RP + L G F N +H+ +N+ I +F GL L+ L+
Sbjct: 16 ISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLH 75
Query: 114 LTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSR 173
+ HN+L + D F GL NL L D+N I + F L LK LIL +N I +L
Sbjct: 76 INHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN 135
Query: 174 LFRMLAKLSILDLSDNPLTDL 194
+FR + L+ LDL N L L
Sbjct: 136 IFRFV-PLTHLDLRGNQLQTL 155
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L+L +N LT + ++F GL N +HL N+I + F L LK L + +N + L
Sbjct: 26 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 85
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L +N +T + P F + L++ + + I+ VP L
Sbjct: 86 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTH 144
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGNQ 262
LDL N + L F+ + R+ L+L+ N+
Sbjct: 145 LDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 176
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ L LH+ N+ + + + SF L L+ L L N+LT + F GL NL L+L++N
Sbjct: 343 YFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 402
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLF 175
I+++ TF + LK L L NN S +F
Sbjct: 403 AIKEILPGTFNPMPKLKVLYL-NNTSSKFYHHIF 435
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNE--------HLVALDLSWNKLSRFPFKLLSKT 396
L+IL E GL NL + NF T E L L L+ N + P +
Sbjct: 81 LEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV 140
Query: 397 KFLQRLDISHNKLQTLSEQD-LQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNST 455
L LD+ N+LQTL L+ + I ++ L N W C+ C + ++ S
Sbjct: 141 P-LTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACN-CDLLQLKTWLENMPPQSI 198
Query: 456 IRVLKCHSPLRLRGATFGSLSFEQLDPCPTTHE 488
I + C+SP +G+ L E + P P +E
Sbjct: 199 IGDVVCNSPPFFKGSILSRLKKESICPTPPVYE 231
Score = 39.5 bits (88), Expect = 0.031
Identities = 23/57 (40%), Positives = 30/57 (52%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
LE L LG N + L F++L RL+KL L+GN L+ + MF L L L N
Sbjct: 346 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYN 402
Score = 38.7 bits (86), Expect = 0.054
Identities = 28/112 (25%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NN ++ L + F L + L N + D+ F + L+ L +
Sbjct: 26 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 85
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+H + LE L N + F L RLK L L+ N + + N+F
Sbjct: 86 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 137
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 47/102 (46%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
L L +N LT L+ F + + + I ++ + L++L + N + L
Sbjct: 26 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 85
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
D F L+ L+ L+ D N ++VI + F + L VL L+ N
Sbjct: 86 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 127
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 70.1 bits (164), Expect = 2e-11
Identities = 69/300 (23%), Positives = 131/300 (43%), Gaps = 2/300 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L+L N + ++ D F +L EL L+ N + + F +L +L+TL L +N++
Sbjct: 68 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 127
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ +F L+ L+ LD+S+N + L +F+D+ +LR + L I+ + + + L
Sbjct: 128 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSL 187
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E+L L + + ++ L L L+L ++ I D F R L VL +S
Sbjct: 188 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLD 247
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
I+H + +V L+ +N S N + E +++ ++L
Sbjct: 248 TMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNRISTIEGSMLHELL- 305
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L L + F +L L++S N+L+ + L+ L + N L
Sbjct: 306 RLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 365
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L I + + + + F L NLR L + N+L + F GL +L +L L+ ++
Sbjct: 138 NLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNL 197
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 198 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 257
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 258 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGG 315
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 316 QLAVVEPYAFRGLNYLRVLNVSGNQ 340
Score = 69.3 bits (162), Expect = 3e-11
Identities = 42/150 (28%), Positives = 71/150 (47%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 214 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 273
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N+IST+ + L +L + L L + P F+ + +LR+
Sbjct: 274 YLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 333
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 334 LNVSGNQLTTLEESVFHSVGNLETLILDSN 363
Score = 63.3 bits (147), Expect = 2e-09
Identities = 44/155 (28%), Positives = 72/155 (46%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F +L EL + + V ++ +F L NLR L L N L + F GL NLT+L +
Sbjct: 86 ASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDIS 145
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I + F+ L +L++L + +N + + R F L L L L LT + E
Sbjct: 146 ENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 205
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+ L + + R + I + + RL+ L++
Sbjct: 206 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 240
Score = 60.5 bits (140), Expect = 2e-08
Identities = 65/308 (21%), Positives = 122/308 (39%), Gaps = 4/308 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T + L L N+I TL F L L+L++N ++ + P F ++ +LR R
Sbjct: 65 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 124
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L+ I ++ + L +LD+ EN L F L L+ L++ N L I F
Sbjct: 125 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGL 184
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L LTL + + H I+ +F + LK + S
Sbjct: 185 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLY-RLKVLEIS-- 241
Query: 335 NLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ P L+ + + + + + +L +P + +L L+LS+N++S +L
Sbjct: 242 HWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSML 301
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLN 453
+ LQ + + +L + + L + +N+ N + S + + + T +L+
Sbjct: 302 HELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 361
Query: 454 STIRVLKC 461
S C
Sbjct: 362 SNPLACDC 369
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/173 (26%), Positives = 76/173 (43%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L + + + ++ Q F +L L L N +++V F L NL L L N ++
Sbjct: 68 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 127
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+ F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F + L
Sbjct: 128 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSL 187
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+C L I T+ + L L L + F L RLK L++
Sbjct: 188 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 240
Score = 58.4 bits (135), Expect = 6e-08
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 257 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQ 316
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 317 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 365
Score = 38.3 bits (85), Expect = 0.071
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 281 VYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 340
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 341 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 399
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 400 EFKDFPDVLLPNYFTCRRARIR 421
>AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein.
Length = 696
Score = 70.1 bits (164), Expect = 2e-11
Identities = 38/119 (31%), Positives = 71/119 (59%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N++EL + ++ + SI + F +NL +L+L +NN+ +V + F+ L++L L++D N++
Sbjct: 376 NVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 435
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S E F L +L+ L + N I ++ F + KL IL L++N L L +VF +
Sbjct: 436 DTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV 494
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N NV S+ L N++ L L N + S+ +F NL L L +N+I + + TF
Sbjct: 361 NRNVSSLADLKP-KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
++L L+ L + +N + TL F L L L++ N + + P F + LRI
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
LLR + ++ V L +L L N F YL + L + ++ L GN
Sbjct: 480 NNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
Score = 62.1 bits (144), Expect = 5e-09
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N+LT + + F N LH+++N + ++ F L +K L + NN+I +
Sbjct: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L L N L D++P F+D+ L + L+ + ++ VP +
Sbjct: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 181
Query: 232 LDLGENLFKYLTSDEFI-SLKRLKKLKLDGN 261
LDL N K L +E + + + ++ L+ N
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F N LH+ N+ + I +F GLQ ++ L++ +N + S F GL +L L D
Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
N + + F+ L L+ LIL +N ISTL + +F+ + ++ LDL N L L
Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITHLDLRGNRLKTL 192
Score = 54.4 bits (125), Expect = 1e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + N+N+ ++ +F L +LR L + N L ++ + F GL NL L++++N
Sbjct: 398 YKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
I+ + TF + L+ LIL NN + +L +F ++ LS L L +N
Sbjct: 458 AIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS-LSKLSLHNN 504
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L + +++ + F N L++ +N L +V F GL + LH++
Sbjct: 55 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 114
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+N I+ +TF L L+ L N + + F+ L KL +L L+DN ++ L VF
Sbjct: 115 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ I HL + R L ++ +P + E+ L +N
Sbjct: 175 QYVPITHLDLRGNR--LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS-EQDLQR 419
L++I F L L L+ N +S P + + LD+ N+L+TL E+ L++
Sbjct: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQ 200
Query: 420 LEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQ 479
+ IAE+ L N W C C ++ ++ N+ I + C +P RL+G + EQ
Sbjct: 201 IPGIAEILLEDNPWDC-TCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETT-EQ 258
Query: 480 LDPCPTTHEAQMSVIA 495
D CP + S+ A
Sbjct: 259 -DLCPLKNRVDSSLPA 273
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
++LR L++ ++ + ++ + F GLQNL LN+ +N + ++ F + L L L++N
Sbjct: 423 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 482
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + + F + SL L L NN L V+ + L + +DL NP
Sbjct: 483 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
L++++ L L +N+I ++ F L +LDL +N + + FK++ LR
Sbjct: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L ++ + + + LE L++ N + + F ++ +L+ L L+ N L + ++F
Sbjct: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA- 492
Query: 274 NRELHVLTLSRN 285
L L+L N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 38.3 bits (85), Expect = 0.071
Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
N +S+L L L+ + L L DN + + F D ++L + + + +
Sbjct: 361 NRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ L L + N L+ ++F L+ L+ L ++ N + +I+ F +L +L L+
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 284 RN 285
N
Sbjct: 480 NN 481
>AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 70.1 bits (164), Expect = 2e-11
Identities = 38/119 (31%), Positives = 71/119 (59%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N++EL + ++ + SI + F +NL +L+L +NN+ +V + F+ L++L L++D N++
Sbjct: 376 NVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 435
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S E F L +L+ L + N I ++ F + KL IL L++N L L +VF +
Sbjct: 436 DTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV 494
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N NV S+ L N++ L L N + S+ +F NL L L +N+I + + TF
Sbjct: 361 NRNVSSLADLKP-KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
++L L+ L + +N + TL F L L L++ N + + P F + LRI
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
LLR + ++ V L +L L N F YL + L + ++ L GN
Sbjct: 480 NNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
Score = 62.1 bits (144), Expect = 5e-09
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N+LT + + F N LH+++N + ++ F L +K L + NN+I +
Sbjct: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L L N L D++P F+D+ L + L+ + ++ VP +
Sbjct: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 181
Query: 232 LDLGENLFKYLTSDEFI-SLKRLKKLKLDGN 261
LDL N K L +E + + + ++ L+ N
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F N LH+ N+ + I +F GLQ ++ L++ +N + S F GL +L L D
Sbjct: 79 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 138
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
N + + F+ L L+ LIL +N ISTL + +F+ + ++ LDL N L L
Sbjct: 139 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITHLDLRGNRLKTL 192
Score = 54.4 bits (125), Expect = 1e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + N+N+ ++ +F L +LR L + N L ++ + F GL NL L++++N
Sbjct: 398 YKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
I+ + TF + L+ LIL NN + +L +F ++ LS L L +N
Sbjct: 458 AIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS-LSKLSLHNN 504
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L + +++ + F N L++ +N L +V F GL + LH++
Sbjct: 55 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 114
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+N I+ +TF L L+ L N + + F+ L KL +L L+DN ++ L VF
Sbjct: 115 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ I HL + R L ++ +P + E+ L +N
Sbjct: 175 QYVPITHLDLRGNR--LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS-EQDLQR 419
L++I F L L L+ N +S P + + LD+ N+L+TL E+ L++
Sbjct: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQ 200
Query: 420 LEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQ 479
+ IAE+ L N W C C ++ ++ N+ I + C +P RL+G + EQ
Sbjct: 201 IPGIAEILLEDNPWDC-TCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETT-EQ 258
Query: 480 LDPCPTTHEAQMSVIA 495
D CP + S+ A
Sbjct: 259 -DLCPLKNRVDSSLPA 273
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
++LR L++ ++ + ++ + F GLQNL LN+ +N + ++ F + L L L++N
Sbjct: 423 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 482
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + + F + SL L L NN L V+ + L + +DL NP
Sbjct: 483 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
L++++ L L +N+I ++ F L +LDL +N + + FK++ LR
Sbjct: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L ++ + + + LE L++ N + + F ++ +L+ L L+ N L + ++F
Sbjct: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA- 492
Query: 274 NRELHVLTLSRN 285
L L+L N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 38.3 bits (85), Expect = 0.071
Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
N +S+L L L+ + L L DN + + F D ++L + + + +
Sbjct: 361 NRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ L L + N L+ ++F L+ L+ L ++ N + +I+ F +L +L L+
Sbjct: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
Query: 284 RN 285
N
Sbjct: 480 NN 481
>AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1
receptor-like protein 3 protein.
Length = 858
Score = 70.1 bits (164), Expect = 2e-11
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++R L + + V S+ F L++L+VLNL +N + + + F GL NL L+L +N +
Sbjct: 289 SVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLL 348
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S F L + + L N I+ + + F+ L KL LDL DN LT ++ I
Sbjct: 349 GELCSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH--FIPSIP 406
Query: 204 HLRIFKCRRCLLRRIN--TQIYHLVP-RLEELDL 234
+ + + L +IN + HL RLE LD+
Sbjct: 407 DIFLSGNKLVTLPKINLTANLIHLSENRLENLDI 440
Score = 57.6 bits (133), Expect = 1e-07
Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 12/196 (6%)
Query: 94 NVPSIGQFSFWGL--QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ Q +F GL ++R L+L+H + S+ + F L +L L+L +N I +++ E F
Sbjct: 273 NIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAF 332
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L+ L L+ N + L S F L K++ +DL N + + + FK ++ L+ R
Sbjct: 333 YGLDNLQVLNLSYNLLGELCSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLR 392
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-SVIVDNM 270
L I H +P + ++ L N K +T + L + L N+L ++ +
Sbjct: 393 DNALTTI-----HFIPSIPDIFLSGN--KLVTLPKINLTANL--IHLSENRLENLDILYF 443
Query: 271 FGRNRELHVLTLSRNR 286
R L +L L++NR
Sbjct: 444 LLRVPHLQILILNQNR 459
Score = 57.2 bits (132), Expect = 1e-07
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 120 TSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLA 179
T + D F GL +L L+L+HN++ + F HLT+L+ L L +N+++ L + A
Sbjct: 491 TELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN--DLPA 548
Query: 180 KLSILDLSDNPLTDLNPEVFKDIQHLRI 207
L ILD+S N L NP+VF + L I
Sbjct: 549 NLEILDISRNQLLAPNPDVFVSLSVLDI 576
Score = 56.4 bits (130), Expect = 3e-07
Identities = 71/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 130 LINLTE-LHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-TLVSRLFRMLAKLSILDLS 187
++N TE L L N+I +++ +F L L+ L L + T+ FR L L ILDL
Sbjct: 44 VLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLG 103
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYL-TS 244
+ + L+P+ F+ + HL + C L + + + L LDL +N + L
Sbjct: 104 SSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLH 163
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L LK + NQ+ ++ ++ L TLS
Sbjct: 164 PSFGKLNSLKSIDFSSNQIFLVCEHEL---EPLQGKTLSFFSLAANSLYSRVSVDWGKCM 220
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIVLQILPEIHGVGLANLSLQ 362
+ N + V + T++ +GN N A L + I G G +++
Sbjct: 221 NPFRNMV-----LEIVDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIK 275
Query: 363 EIPQNFFT--YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ QN F + LDLS + ++ K L+ L++++NK+ ++++ L
Sbjct: 276 DPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGL 335
Query: 421 EAIAEVNLMKN 431
+ + +NL N
Sbjct: 336 DNLQVLNLSYN 346
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVP-SIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
+F I + PF+ L+ L + + P +I + +F L NLR+L+L + + + D
Sbjct: 54 SFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPD 113
Query: 126 NFRGLINLTELHLDHNHIEQ--MSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLS 182
F+GL +L EL L + + FR+L +L L L+ NQI +L + F L L
Sbjct: 114 AFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLK 173
Query: 183 ILDLSDNPL 191
+D S N +
Sbjct: 174 SIDFSSNQI 182
Score = 35.1 bits (77), Expect = 0.66
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 20/371 (5%)
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRG 129
L GP+F P+ + R N+ + Q L L L+ N + +V A +F
Sbjct: 13 LMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV----LNTTERLLLSFNYIRTVTASSFPF 68
Query: 130 LINLTELHLDHNHIE-QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L L L + + E FR+L +L+ L L +++I L F+ L L L L
Sbjct: 69 LEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYF 128
Query: 189 NPLTD--LNPEVFKDIQHLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENLFKYLTSD 245
L+D L F++++ L + +R + + + L+ +D N +
Sbjct: 129 CGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEH 188
Query: 246 EFISL--KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
E L K L L N L V +G+ + RN
Sbjct: 189 ELEPLQGKTLSFFSLAANSLYSRVSVDWGK-----CMNPFRNMVLEIVDVSGNGWTVDIT 243
Query: 304 XDISHNKIDRFHLQTFAPVV-DSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSL 361
+ S N I + Q F+ ++ + F +N+ ++ + + L++ +
Sbjct: 244 GNFS-NAISKS--QAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 300
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLE 421
+ F + L L+L++NK+++ + LQ L++S+N L L + L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELCSSNFYGLP 360
Query: 422 AIAEVNLMKNN 432
+A ++L KN+
Sbjct: 361 KVAYIDLQKNH 371
Score = 33.1 bits (72), Expect = 2.7
Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-----VADNFRG--------LINLT 134
+ + +++ I +F L+ L+ L+L N LT++ + D F INLT
Sbjct: 365 IDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLT 424
Query: 135 E--LHLDHNHIEQMSSETFR-HLTSLKTLILANNQISTLVS-RLFRMLAKLSILDLSDNP 190
+HL N +E + F + L+ LIL N+ S+ + L L L +N
Sbjct: 425 ANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENM 484
Query: 191 L-----TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
L T+L +VF+ + HL++ L + ++ + L L L N L+ +
Sbjct: 485 LQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN 544
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ + L+ L + NQL ++F L VL ++ N+
Sbjct: 545 DLPA--NLEILDISRNQLLAPNPDVF---VSLSVLDITHNK 580
>AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein.
Length = 760
Score = 70.1 bits (164), Expect = 2e-11
Identities = 38/119 (31%), Positives = 71/119 (59%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N++EL + ++ + SI + F +NL +L+L +NN+ +V + F+ L++L L++D N++
Sbjct: 440 NVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 499
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +S E F L +L+ L + N I ++ F + KL IL L++N L L +VF +
Sbjct: 500 DTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV 558
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N NV S+ L N++ L L N + S+ +F NL L L +N+I + + TF
Sbjct: 425 NRNVSSLADLKP-KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 483
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
++L L+ L + +N + TL F L L L++ N + + P F + LRI
Sbjct: 484 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 543
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
LLR + ++ V L +L L N F YL + L + ++ L GN
Sbjct: 544 NNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 593
Score = 62.1 bits (144), Expect = 5e-09
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N+LT + + F N LH+++N + ++ F L +K L + NN+I +
Sbjct: 127 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 186
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+ F L L L N L D++P F+D+ L + L+ + ++ VP +
Sbjct: 187 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 245
Query: 232 LDLGENLFKYLTSDEFI-SLKRLKKLKLDGN 261
LDL N K L +E + + + ++ L+ N
Sbjct: 246 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 276
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F N LH+ N+ + I +F GLQ ++ L++ +N + S F GL +L L D
Sbjct: 143 ANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQAD 202
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
N + + F+ L L+ LIL +N ISTL + +F+ + ++ LDL N L L
Sbjct: 203 FNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITHLDLRGNRLKTL 256
Score = 54.4 bits (125), Expect = 1e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
+ NL L + N+N+ ++ +F L +LR L + N L ++ + F GL NL L++++N
Sbjct: 462 YKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 521
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
I+ + TF + L+ LIL NN + +L +F ++ LS L L +N
Sbjct: 522 AIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS-LSKLSLHNN 568
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
AP L + +++ + F N L++ +N L +V F GL + LH++
Sbjct: 119 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 178
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
+N I+ +TF L L+ L N + + F+ L KL +L L+DN ++ L VF
Sbjct: 179 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 238
Query: 200 K--DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ I HL + R L ++ +P + E+ L +N
Sbjct: 239 QYVPITHLDLRGNR--LKTLPYEEVLEQIPGIAEILLEDN 276
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS-EQDLQR 419
L++I F L L L+ N +S P + + LD+ N+L+TL E+ L++
Sbjct: 206 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQ 264
Query: 420 LEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQ 479
+ IAE+ L N W C C ++ ++ N+ I + C +P RL+G + EQ
Sbjct: 265 IPGIAEILLEDNPWDC-TCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETT-EQ 322
Query: 480 LDPCPTTHEAQMSVIA 495
D CP + S+ A
Sbjct: 323 -DLCPLKNRVDSSLPA 337
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
++LR L++ ++ + ++ + F GLQNL LN+ +N + ++ F + L L L++N
Sbjct: 487 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 546
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + + F + SL L L NN L V+ + L + +DL NP
Sbjct: 547 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 594
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Query: 154 LTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
L++++ L L +N+I ++ F L +LDL +N + + FK++ LR
Sbjct: 438 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 497
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
L ++ + + + LE L++ N + + F ++ +L+ L L+ N L + ++F
Sbjct: 498 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA- 556
Query: 274 NRELHVLTLSRN 285
L L+L N
Sbjct: 557 GVSLSKLSLHNN 568
Score = 38.3 bits (85), Expect = 0.071
Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
N +S+L L L+ + L L DN + + F D ++L + + + +
Sbjct: 425 NRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 483
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ L L + N L+ ++F L+ L+ L ++ N + +I+ F +L +L L+
Sbjct: 484 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 543
Query: 284 RN 285
N
Sbjct: 544 NN 545
>BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein.
Length = 858
Score = 69.7 bits (163), Expect = 3e-11
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++R L + + V S+ F L++L+VLNL +N + + + F GL NL L+L +N +
Sbjct: 289 SVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLL 348
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S F L + + L N I+ + + F+ L KL LDL DN LT ++ I
Sbjct: 349 GELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH--FIPSIP 406
Query: 204 HLRIFKCRRCLLRRIN--TQIYHLVP-RLEELDL 234
+ + + L +IN + HL RLE LD+
Sbjct: 407 DIFLSGNKLVTLPKINLTANLIHLSENRLENLDI 440
Score = 57.6 bits (133), Expect = 1e-07
Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 12/196 (6%)
Query: 94 NVPSIGQFSFWGL--QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ Q +F GL ++R L+L+H + S+ + F L +L L+L +N I +++ E F
Sbjct: 273 NIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAF 332
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L+ L L+ N + L S F L K++ +DL N + + + FK ++ L+ R
Sbjct: 333 YGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLR 392
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-SVIVDNM 270
L I H +P + ++ L N K +T + L + L N+L ++ +
Sbjct: 393 DNALTTI-----HFIPSIPDIFLSGN--KLVTLPKINLTANL--IHLSENRLENLDILYF 443
Query: 271 FGRNRELHVLTLSRNR 286
R L +L L++NR
Sbjct: 444 LLRVPHLQILILNQNR 459
Score = 57.2 bits (132), Expect = 1e-07
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 120 TSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLA 179
T + D F GL +L L+L+HN++ + F HLT+L+ L L +N+++ L + A
Sbjct: 491 TELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN--DLPA 548
Query: 180 KLSILDLSDNPLTDLNPEVFKDIQHLRI 207
L ILD+S N L NP+VF + L I
Sbjct: 549 NLEILDISRNQLLAPNPDVFVSLSVLDI 576
Score = 56.0 bits (129), Expect = 3e-07
Identities = 71/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 130 LINLTE-LHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-TLVSRLFRMLAKLSILDLS 187
++N TE L L N+I +++ +F L L+ L L + T+ FR L L ILDL
Sbjct: 44 VLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLG 103
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYL-TS 244
+ + L+P+ F+ + HL + C L + + + L LDL +N + L
Sbjct: 104 SSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLH 163
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L LK + NQ+ ++ ++ L TLS
Sbjct: 164 PSFGKLNSLKSIDFSSNQIFLVCEHEL---EPLQGKTLSFFSLAANSLYSRVSVDWGKCM 220
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIVLQILPEIHGVGLANLSLQ 362
+ N + V + T++ +GN N A L + I G G +++
Sbjct: 221 NPFRNMV-----LEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIK 275
Query: 363 EIPQNFFT--YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ QN F + LDLS + ++ K L+ L++++NK+ ++++ L
Sbjct: 276 DPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGL 335
Query: 421 EAIAEVNLMKN 431
+ + +NL N
Sbjct: 336 DNLQVLNLSYN 346
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVP-SIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
+F I + PF+ L+ L + + P +I + +F L NLR+L+L + + + D
Sbjct: 54 SFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPD 113
Query: 126 NFRGLINLTELHLDHNHIEQ--MSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLS 182
F+GL +L EL L + + FR+L +L L L+ NQI +L + F L L
Sbjct: 114 AFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLK 173
Query: 183 ILDLSDNPL 191
+D S N +
Sbjct: 174 SIDFSSNQI 182
Score = 34.7 bits (76), Expect = 0.88
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 20/371 (5%)
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRG 129
L GP+F P+ + R N+ + Q L L L+ N + +V A +F
Sbjct: 13 LMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV----LNTTERLLLSFNYIRTVTASSFPF 68
Query: 130 LINLTELHLDHNHIE-QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L L L + + E FR+L +L+ L L +++I L F+ L L L L
Sbjct: 69 LEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYF 128
Query: 189 NPLTD--LNPEVFKDIQHLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENLFKYLTSD 245
L+D L F++++ L + +R + + + L+ +D N +
Sbjct: 129 CGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEH 188
Query: 246 EFISL--KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
E L K L L N L V +G+ + RN
Sbjct: 189 ELEPLQGKTLSFFSLAANSLYSRVSVDWGK-----CMNPFRNMVLEILDVSGNGWTVDIT 243
Query: 304 XDISHNKIDRFHLQTFAPVV-DSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSL 361
+ S N I + Q F+ ++ + F +N+ ++ + + L++ +
Sbjct: 244 GNFS-NAISKS--QAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 300
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLE 421
+ F + L L+L++NK+++ + LQ L++S+N L L + L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLP 360
Query: 422 AIAEVNLMKNN 432
+A ++L KN+
Sbjct: 361 KVAYIDLQKNH 371
Score = 33.1 bits (72), Expect = 2.7
Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-----VADNFRG--------LINLT 134
+ + +++ I +F L+ L+ L+L N LT++ + D F INLT
Sbjct: 365 IDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLT 424
Query: 135 E--LHLDHNHIEQMSSETFR-HLTSLKTLILANNQISTLVS-RLFRMLAKLSILDLSDNP 190
+HL N +E + F + L+ LIL N+ S+ + L L L +N
Sbjct: 425 ANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENM 484
Query: 191 L-----TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
L T+L +VF+ + HL++ L + ++ + L L L N L+ +
Sbjct: 485 LQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN 544
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ + L+ L + NQL ++F L VL ++ N+
Sbjct: 545 DLPA--NLEILDISRNQLLAPNPDVF---VSLSVLDITHNK 580
>AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5
protein.
Length = 858
Score = 69.7 bits (163), Expect = 3e-11
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++R L + + V S+ F L++L+VLNL +N + + + F GL NL L+L +N +
Sbjct: 289 SVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLL 348
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S F L + + L N I+ + + F+ L KL LDL DN LT ++ I
Sbjct: 349 GELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH--FIPSIP 406
Query: 204 HLRIFKCRRCLLRRIN--TQIYHLVP-RLEELDL 234
+ + + L +IN + HL RLE LD+
Sbjct: 407 DIFLSGNKLVTLPKINLTANLIHLSENRLENLDI 440
Score = 57.6 bits (133), Expect = 1e-07
Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 12/196 (6%)
Query: 94 NVPSIGQFSFWGL--QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ Q +F GL ++R L+L+H + S+ + F L +L L+L +N I +++ E F
Sbjct: 273 NIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAF 332
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L+ L L+ N + L S F L K++ +DL N + + + FK ++ L+ R
Sbjct: 333 YGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLR 392
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-SVIVDNM 270
L I H +P + ++ L N K +T + L + L N+L ++ +
Sbjct: 393 DNALTTI-----HFIPSIPDIFLSGN--KLVTLPKINLTANL--IHLSENRLENLDILYF 443
Query: 271 FGRNRELHVLTLSRNR 286
R L +L L++NR
Sbjct: 444 LLRVPHLQILILNQNR 459
Score = 57.2 bits (132), Expect = 1e-07
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 120 TSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLA 179
T + D F GL +L L+L+HN++ + F HLT+L+ L L +N+++ L + A
Sbjct: 491 TELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN--DLPA 548
Query: 180 KLSILDLSDNPLTDLNPEVFKDIQHLRI 207
L ILD+S N L NP+VF + L I
Sbjct: 549 NLEILDISRNQLLAPNPDVFVSLSVLDI 576
Score = 56.0 bits (129), Expect = 3e-07
Identities = 71/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 130 LINLTE-LHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-TLVSRLFRMLAKLSILDLS 187
++N TE L L N+I +++ +F L L+ L L + T+ FR L L ILDL
Sbjct: 44 VLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLG 103
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYL-TS 244
+ + L+P+ F+ + HL + C L + + + L LDL +N + L
Sbjct: 104 SSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLH 163
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L LK + NQ+ ++ ++ L TLS
Sbjct: 164 PSFGKLNSLKSIDFSSNQIFLVCEHEL---EPLQGKTLSFFSLAANSLYSRVSVDWGKCM 220
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIVLQILPEIHGVGLANLSLQ 362
+ N + V + T++ +GN N A L + I G G +++
Sbjct: 221 NPFRNMV-----LEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIK 275
Query: 363 EIPQNFFT--YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ QN F + LDLS + ++ K L+ L++++NK+ ++++ L
Sbjct: 276 DPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGL 335
Query: 421 EAIAEVNLMKN 431
+ + +NL N
Sbjct: 336 DNLQVLNLSYN 346
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVP-SIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
+F I + PF+ L+ L + + P +I + +F L NLR+L+L + + + D
Sbjct: 54 SFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPD 113
Query: 126 NFRGLINLTELHLDHNHIEQ--MSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLS 182
F+GL +L EL L + + FR+L +L L L+ NQI +L + F L L
Sbjct: 114 AFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLK 173
Query: 183 ILDLSDNPL 191
+D S N +
Sbjct: 174 SIDFSSNQI 182
Score = 34.7 bits (76), Expect = 0.88
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 20/371 (5%)
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRG 129
L GP+F P+ + R N+ + Q L L L+ N + +V A +F
Sbjct: 13 LMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV----LNTTERLLLSFNYIRTVTASSFPF 68
Query: 130 LINLTELHLDHNHIE-QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L L L + + E FR+L +L+ L L +++I L F+ L L L L
Sbjct: 69 LEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYF 128
Query: 189 NPLTD--LNPEVFKDIQHLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENLFKYLTSD 245
L+D L F++++ L + +R + + + L+ +D N +
Sbjct: 129 CGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEH 188
Query: 246 EFISL--KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
E L K L L N L V +G+ + RN
Sbjct: 189 ELEPLQGKTLSFFSLAANSLYSRVSVDWGK-----CMNPFRNMVLEILDVSGNGWTVDIT 243
Query: 304 XDISHNKIDRFHLQTFAPVV-DSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSL 361
+ S N I + Q F+ ++ + F +N+ ++ + + L++ +
Sbjct: 244 GNFS-NAISKS--QAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 300
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLE 421
+ F + L L+L++NK+++ + LQ L++S+N L L + L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLP 360
Query: 422 AIAEVNLMKNN 432
+A ++L KN+
Sbjct: 361 KVAYIDLQKNH 371
Score = 33.1 bits (72), Expect = 2.7
Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-----VADNFRG--------LINLT 134
+ + +++ I +F L+ L+ L+L N LT++ + D F INLT
Sbjct: 365 IDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLT 424
Query: 135 E--LHLDHNHIEQMSSETFR-HLTSLKTLILANNQISTLVS-RLFRMLAKLSILDLSDNP 190
+HL N +E + F + L+ LIL N+ S+ + L L L +N
Sbjct: 425 ANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENM 484
Query: 191 L-----TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
L T+L +VF+ + HL++ L + ++ + L L L N L+ +
Sbjct: 485 LQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN 544
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ + L+ L + NQL ++F L VL ++ N+
Sbjct: 545 DLPA--NLEILDISRNQLLAPNPDVF---VSLSVLDITHNK 580
>AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5
protein.
Length = 858
Score = 69.7 bits (163), Expect = 3e-11
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++R L + + V S+ F L++L+VLNL +N + + + F GL NL L+L +N +
Sbjct: 289 SVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLL 348
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S F L + + L N I+ + + F+ L KL LDL DN LT ++ I
Sbjct: 349 GELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH--FIPSIP 406
Query: 204 HLRIFKCRRCLLRRIN--TQIYHLVP-RLEELDL 234
+ + + L +IN + HL RLE LD+
Sbjct: 407 DIFLSGNKLVTLPKINLTANLIHLSENRLENLDI 440
Score = 57.6 bits (133), Expect = 1e-07
Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 12/196 (6%)
Query: 94 NVPSIGQFSFWGL--QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ Q +F GL ++R L+L+H + S+ + F L +L L+L +N I +++ E F
Sbjct: 273 NIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAF 332
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L+ L L+ N + L S F L K++ +DL N + + + FK ++ L+ R
Sbjct: 333 YGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLR 392
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-SVIVDNM 270
L I H +P + ++ L N K +T + L + L N+L ++ +
Sbjct: 393 DNALTTI-----HFIPSIPDIFLSGN--KLVTLPKINLTANL--IHLSENRLENLDILYF 443
Query: 271 FGRNRELHVLTLSRNR 286
R L +L L++NR
Sbjct: 444 LLRVPHLQILILNQNR 459
Score = 57.2 bits (132), Expect = 1e-07
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 120 TSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLA 179
T + D F GL +L L+L+HN++ + F HLT+L+ L L +N+++ L + A
Sbjct: 491 TELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN--DLPA 548
Query: 180 KLSILDLSDNPLTDLNPEVFKDIQHLRI 207
L ILD+S N L NP+VF + L I
Sbjct: 549 NLEILDISRNQLLAPNPDVFVSLSVLDI 576
Score = 56.0 bits (129), Expect = 3e-07
Identities = 71/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 130 LINLTE-LHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-TLVSRLFRMLAKLSILDLS 187
++N TE L L N+I +++ +F L L+ L L + T+ FR L L ILDL
Sbjct: 44 VLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLG 103
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYL-TS 244
+ + L+P+ F+ + HL + C L + + + L LDL +N + L
Sbjct: 104 SSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLH 163
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L LK + NQ+ ++ ++ L TLS
Sbjct: 164 PSFGKLNSLKSIDFSSNQIFLVCEHEL---EPLQGKTLSFFSLAANSLYSRVSVDWGKCM 220
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIVLQILPEIHGVGLANLSLQ 362
+ N + V + T++ +GN N A L + I G G +++
Sbjct: 221 NPFRNMV-----LEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIK 275
Query: 363 EIPQNFFT--YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ QN F + LDLS + ++ K L+ L++++NK+ ++++ L
Sbjct: 276 DPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGL 335
Query: 421 EAIAEVNLMKN 431
+ + +NL N
Sbjct: 336 DNLQVLNLSYN 346
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVP-SIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
+F I + PF+ L+ L + + P +I + +F L NLR+L+L + + + D
Sbjct: 54 SFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPD 113
Query: 126 NFRGLINLTELHLDHNHIEQ--MSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLS 182
F+GL +L EL L + + FR+L +L L L+ NQI +L + F L L
Sbjct: 114 AFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLK 173
Query: 183 ILDLSDNPL 191
+D S N +
Sbjct: 174 SIDFSSNQI 182
Score = 34.7 bits (76), Expect = 0.88
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 20/371 (5%)
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRG 129
L GP+F P+ + R N+ + Q L L L+ N + +V A +F
Sbjct: 13 LMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV----LNTTERLLLSFNYIRTVTASSFPF 68
Query: 130 LINLTELHLDHNHIE-QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L L L + + E FR+L +L+ L L +++I L F+ L L L L
Sbjct: 69 LEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYF 128
Query: 189 NPLTD--LNPEVFKDIQHLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENLFKYLTSD 245
L+D L F++++ L + +R + + + L+ +D N +
Sbjct: 129 CGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEH 188
Query: 246 EFISL--KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
E L K L L N L V +G+ + RN
Sbjct: 189 ELEPLQGKTLSFFSLAANSLYSRVSVDWGK-----CMNPFRNMVLEILDVSGNGWTVDIT 243
Query: 304 XDISHNKIDRFHLQTFAPVV-DSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSL 361
+ S N I + Q F+ ++ + F +N+ ++ + + L++ +
Sbjct: 244 GNFS-NAISKS--QAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 300
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLE 421
+ F + L L+L++NK+++ + LQ L++S+N L L + L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLP 360
Query: 422 AIAEVNLMKNN 432
+A ++L KN+
Sbjct: 361 KVAYIDLQKNH 371
Score = 33.1 bits (72), Expect = 2.7
Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-----VADNFRG--------LINLT 134
+ + +++ I +F L+ L+ L+L N LT++ + D F INLT
Sbjct: 365 IDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLT 424
Query: 135 E--LHLDHNHIEQMSSETFR-HLTSLKTLILANNQISTLVS-RLFRMLAKLSILDLSDNP 190
+HL N +E + F + L+ LIL N+ S+ + L L L +N
Sbjct: 425 ANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENM 484
Query: 191 L-----TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
L T+L +VF+ + HL++ L + ++ + L L L N L+ +
Sbjct: 485 LQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN 544
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ + L+ L + NQL ++F L VL ++ N+
Sbjct: 545 DLPA--NLEILDISRNQLLAPNPDVF---VSLSVLDITHNK 580
>BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein.
Length = 858
Score = 69.3 bits (162), Expect = 3e-11
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
++R L + + V S+ F L++L+VLNL +N + + + F GL NL L+L +N +
Sbjct: 289 SVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLL 348
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S F L + + L N I+ + + F+ L KL LDL DN LT ++ I
Sbjct: 349 GELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLRTLDLRDNALTTIH--FIPSIP 406
Query: 204 HLRIFKCRRCLLRRIN--TQIYHLVP-RLEELDL 234
+ + + L +IN + HL RLE LD+
Sbjct: 407 DIFLSGNKLVTLPKINLTANLIHLSENRLENLDI 440
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/196 (28%), Positives = 96/196 (48%), Gaps = 12/196 (6%)
Query: 94 NVPSIGQFSFWGL--QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ Q +F GL ++R L+L+H + S+ + F L +L L+L +N I +++ E F
Sbjct: 273 NIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAF 332
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L +L+ L L+ N + L S F L K++ +DL N + + + FK ++ LR R
Sbjct: 333 YGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLRTLDLR 392
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL-SVIVDNM 270
L I H +P + ++ L N K +T + L + L N+L ++ +
Sbjct: 393 DNALTTI-----HFIPSIPDIFLSGN--KLVTLPKINLTANL--IHLSENRLENLDILYF 443
Query: 271 FGRNRELHVLTLSRNR 286
R L +L L++NR
Sbjct: 444 LLRVPHLQILILNQNR 459
Score = 57.2 bits (132), Expect = 1e-07
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 120 TSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLA 179
T + D F GL +L L+L+HN++ + F HLT+L+ L L +N+++ L + A
Sbjct: 491 TELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN--DLPA 548
Query: 180 KLSILDLSDNPLTDLNPEVFKDIQHLRI 207
L ILD+S N L NP+VF + L I
Sbjct: 549 NLEILDISRNQLLAPNPDVFVSLSVLDI 576
Score = 56.0 bits (129), Expect = 3e-07
Identities = 71/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 130 LINLTE-LHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-TLVSRLFRMLAKLSILDLS 187
++N TE L L N+I +++ +F L L+ L L + T+ FR L L ILDL
Sbjct: 44 VLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLG 103
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRR--INTQIYHLVPRLEELDLGENLFKYL-TS 244
+ + L+P+ F+ + HL + C L + + + L LDL +N + L
Sbjct: 104 SSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLH 163
Query: 245 DEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXX 304
F L LK + NQ+ ++ ++ L TLS
Sbjct: 164 PSFGKLNSLKSIDFSSNQIFLVCEHEL---EPLQGKTLSFFSLAANSLYSRVSVDWGKCM 220
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGN--NLPLNEIAIVLQILPEIHGVGLANLSLQ 362
+ N + V + T++ +GN N A L + I G G +++
Sbjct: 221 NPFRNMV-----LEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIK 275
Query: 363 EIPQNFFT--YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ QN F + LDLS + ++ K L+ L++++NK+ ++++ L
Sbjct: 276 DPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGL 335
Query: 421 EAIAEVNLMKN 431
+ + +NL N
Sbjct: 336 DNLQVLNLSYN 346
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Query: 68 NFLTIGPIFTQPAPFVN-LRELHIVNSNVP-SIGQFSFWGLQNLRVLNLTHNNLTSVVAD 125
+F I + PF+ L+ L + + P +I + +F L NLR+L+L + + + D
Sbjct: 54 SFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPD 113
Query: 126 NFRGLINLTELHLDHNHIEQ--MSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLS 182
F+GL +L EL L + + FR+L +L L L+ NQI +L + F L L
Sbjct: 114 AFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLK 173
Query: 183 ILDLSDNPL 191
+D S N +
Sbjct: 174 SIDFSSNQI 182
Score = 34.7 bits (76), Expect = 0.88
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 20/371 (5%)
Query: 70 LTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRG 129
L GP+F P+ + R N+ + Q L L L+ N + +V A +F
Sbjct: 13 LMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV----LNTTERLLLSFNYIRTVTASSFPF 68
Query: 130 LINLTELHLDHNHIE-QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSD 188
L L L L + + E FR+L +L+ L L +++I L F+ L L L L
Sbjct: 69 LEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYF 128
Query: 189 NPLTD--LNPEVFKDIQHLRIFKCRRCLLRRINTQ-IYHLVPRLEELDLGENLFKYLTSD 245
L+D L F++++ L + +R + + + L+ +D N +
Sbjct: 129 CGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEH 188
Query: 246 EFISL--KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
E L K L L N L V +G+ + RN
Sbjct: 189 ELEPLQGKTLSFFSLAANSLYSRVSVDWGK-----CMNPFRNMVLEILDVSGNGWTVDIT 243
Query: 304 XDISHNKIDRFHLQTFAPVV-DSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSL 361
+ S N I + Q F+ ++ + F +N+ ++ + + L++ +
Sbjct: 244 GNFS-NAISKS--QAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 300
Query: 362 QEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLE 421
+ F + L L+L++NK+++ + LQ L++S+N L L + L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLP 360
Query: 422 AIAEVNLMKNN 432
+A ++L KN+
Sbjct: 361 KVAYIDLQKNH 371
Score = 34.7 bits (76), Expect = 0.88
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV-----VADNFRG--------LINLT 134
+ + +++ I +F L+ LR L+L N LT++ + D F INLT
Sbjct: 365 IDLQKNHIAIIQDQTFKFLEKLRTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLT 424
Query: 135 E--LHLDHNHIEQMSSETFR-HLTSLKTLILANNQISTLVS-RLFRMLAKLSILDLSDNP 190
+HL N +E + F + L+ LIL N+ S+ + L L L +N
Sbjct: 425 ANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENM 484
Query: 191 L-----TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
L T+L +VF+ + HL++ L + ++ + L L L N L+ +
Sbjct: 485 LQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN 544
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
+ + L+ L + NQL ++F L VL ++ N+
Sbjct: 545 DLPA--NLEILDISRNQLLAPNPDVF---VSLSVLDITHNK 580
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 68.9 bits (161), Expect = 4e-11
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + L++ N++ V +F L LHL N I + + F +LT+L+ L L NQI
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L +F L L L L N + +++ F + +L++ LL+ + I+ P
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F YL S L+ L ++ L+GN
Sbjct: 498 -LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 67.3 bits (157), Expect = 1e-10
Identities = 48/130 (36%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Query: 68 NFLTIGPIFTQPAPFVNLRE---LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVA 124
NFL I P F+N LH+ N+ + +I +F GL L+ L+L +N L + A
Sbjct: 69 NFLNI----LYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRA 124
Query: 125 DNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSIL 184
D F G+ NL L D+N I+ + F L LK LIL +N IS L +FR A L+ L
Sbjct: 125 DTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR-FASLTHL 183
Query: 185 DLSDNPLTDL 194
D+ N + L
Sbjct: 184 DIRGNRIQKL 193
Score = 58.8 bits (136), Expect = 5e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N +LH++ N I+ + F L L L +NQI+ + +F L L L L+ N
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
+ L PE+F + +L+ L++ I+ + +P L+ L L NL K L F S
Sbjct: 437 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIF-SG 495
Query: 251 KRLKKLKLDGNQLSVI-VDNMFGRNRELHVLTLSRN 285
L +L L N+ + V + + + L + L N
Sbjct: 496 APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 56.0 bits (129), Expect = 3e-07
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 4/159 (2%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P+ N L+ N+ + + +F + L+L +N L ++ F GL L +LHL++
Sbjct: 57 PWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNN 116
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N ++ + ++TF + +L+ L N I + F L KL +L L+DN ++ L +F+
Sbjct: 117 NELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR 176
Query: 201 --DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ HL I R L I + + R+ EL L +N
Sbjct: 177 FASLTHLDIRGNRIQKLPYIG--VLEHIGRVVELQLEDN 213
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)
Query: 1 MSSLVVYNTEAAG-TICPDECTC-TMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVV 58
+S +V Y T T CP C C T DL Q +IP + +HV
Sbjct: 326 LSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHV- 384
Query: 59 IIAAPPDRPNFLTIGPIFTQP-APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN 117
N +I + F L LH+ ++ + I F L NLR L L N
Sbjct: 385 ---------NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGN 435
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
+ + + F GL NL L+L++N I+++S+ TF + +L+ L L NN + +L +F
Sbjct: 436 QIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 495
Query: 178 LAKLSILDLSDN 189
A L+ L+L +N
Sbjct: 496 -APLARLNLRNN 506
Score = 51.2 bits (117), Expect = 9e-06
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L+ +N + + TF + + +L L NN++ + F L+ L L L++N L
Sbjct: 60 NFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNEL 119
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L + F I++L + L++ I ++ + +L+ L L +NL +L D
Sbjct: 120 KILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFL-PDNIFRFA 178
Query: 252 RLKKLKLDGNQL 263
L L + GN++
Sbjct: 179 SLTHLDIRGNRI 190
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F GL NL+ L L +N + + A F + NL L+L++N +
Sbjct: 426 NLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLL 485
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + F L L L NN+ L VS + L L+ +DL NP
Sbjct: 486 KSLPVYIFSG-APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 532
Score = 44.8 bits (101), Expect = 8e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
NN ++ L F + L L +N L ++ F + L+ L+ + +
Sbjct: 68 NNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTF 127
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ LE L NL KY+ F L +LK L L+ N +S + DN+F R L L +
Sbjct: 128 LGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF-RFASLTHLDIR 186
Query: 284 RNR 286
NR
Sbjct: 187 GNR 189
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 68.9 bits (161), Expect = 4e-11
Identities = 60/194 (30%), Positives = 95/194 (48%), Gaps = 23/194 (11%)
Query: 13 GTICPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTI 72
G CP C C M T+V C ++ IP D + +V + + N L +
Sbjct: 26 GKACPRRCACYMP--------TEVHCTFRYLTSIP-DSIPPNVERINLGY-----NSL-V 70
Query: 73 GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLIN 132
+ T + L L + ++ + +I +F LQ L+VL +++N + + D F GL +
Sbjct: 71 RLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRS 130
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIS-----TLVSRLFRMLAKLS---IL 184
LT LH+DHN+IE ++ E F L L+ + L NQ++ T VS + + K+S L
Sbjct: 131 LTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKISFIKFL 190
Query: 185 DLSDNPLTDLNPEV 198
LSDN LT L E+
Sbjct: 191 YLSDNFLTSLPQEM 204
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/126 (27%), Positives = 65/126 (51%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N+ +++ +++ + + F GL L +L L N + ++ F L L L + +N +
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKV 117
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ +TF L SL L + +N I + +F L L ++ L N LT L+P+ F +
Sbjct: 118 RKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLS 177
Query: 204 HLRIFK 209
+L+IFK
Sbjct: 178 YLQIFK 183
Score = 61.3 bits (142), Expect = 9e-09
Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 1/142 (0%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N+ +NL +N+L ++ +F GL L L L N I + +TF L +L+ L ++ N++
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKV 117
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L F L L+ L + N + +NPEVF + LR+ L +++ + +
Sbjct: 118 RKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLS 177
Query: 228 RLEELDLGENLFKYLTSDEFIS 249
L+ + F YL SD F++
Sbjct: 178 YLQIFKISFIKFLYL-SDNFLT 198
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 8/142 (5%)
Query: 150 TFRHLTSLKTLILAN--------NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKD 201
TFR+LTS+ I N N + L+ F L KL +L L N + + + F D
Sbjct: 44 TFRYLTSIPDSIPPNVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSD 103
Query: 202 IQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+Q L++ K +R++ ++ + L L + N +++ + F L L+ + L+GN
Sbjct: 104 LQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGN 163
Query: 262 QLSVIVDNMFGRNRELHVLTLS 283
QL+ + + F L + +S
Sbjct: 164 QLTKLHPDTFVSLSYLQIFKIS 185
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/138 (25%), Positives = 65/138 (47%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N+ ++L +N + ++ F LT L+ L+L +N I T+ + F L L +L +S N +
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKV 117
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L + F ++ L + IN ++++ + L + L N L D F+SL
Sbjct: 118 RKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLS 177
Query: 252 RLKKLKLDGNQLSVIVDN 269
L+ K+ + + DN
Sbjct: 178 YLQIFKISFIKFLYLSDN 195
Score = 35.9 bits (79), Expect = 0.38
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 18/198 (9%)
Query: 239 FKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXX 298
F+YLTS ++++ L N L +++ F +L +L L N
Sbjct: 45 FRYLTSIPDSIPPNVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDL 104
Query: 299 XXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLAN 358
+S+NK+ + TF + SL ++ NN+ I PE+ GL
Sbjct: 105 QALQVLKMSYNKVRKLQKDTFYGL-RSLTRLHMDHNNIEF--------INPEVF-YGLNF 154
Query: 359 LSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L L + N T + LS+ ++ FK+ F++ L +S N L +L ++ +
Sbjct: 155 LRLVHLEGNQLTKLHPDTFVSLSYLQI----FKI----SFIKFLYLSDNFLTSLPQEMVS 206
Query: 419 RLEAIAEVNLMKNNWHCD 436
+ + + L N W CD
Sbjct: 207 YMPDLDSLYLHGNPWTCD 224
>AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein
protein.
Length = 689
Score = 68.9 bits (161), Expect = 4e-11
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + L++ N++ V +F L LHL N I + + F +LT+L+ L L NQI
Sbjct: 230 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 289
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L +F L L L L N + +++ F + +L++ LL+ + I+ P
Sbjct: 290 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 349
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F YL S L+ L ++ L+GN
Sbjct: 350 -LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 58.8 bits (136), Expect = 5e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N +LH++ N I+ + F L L L +NQI+ + +F L L L L+ N
Sbjct: 229 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 288
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
+ L PE+F + +L+ L++ I+ + +P L+ L L NL K L F S
Sbjct: 289 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIF-SG 347
Query: 251 KRLKKLKLDGNQLSVI-VDNMFGRNRELHVLTLSRN 285
L +L L N+ + V + + + L + L N
Sbjct: 348 APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)
Query: 1 MSSLVVYNTEAAG-TICPDECTC-TMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVV 58
+S +V Y T T CP C C T DL Q +IP + +HV
Sbjct: 178 LSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHV- 236
Query: 59 IIAAPPDRPNFLTIGPIFTQP-APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN 117
N +I + F L LH+ ++ + I F L NLR L L N
Sbjct: 237 ---------NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGN 287
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
+ + + F GL NL L+L++N I+++S+ TF + +L+ L L NN + +L +F
Sbjct: 288 QIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 347
Query: 178 LAKLSILDLSDN 189
A L+ L+L +N
Sbjct: 348 -APLARLNLRNN 358
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F GL NL+ L L +N + + A F + NL L+L++N +
Sbjct: 278 NLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLL 337
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + F L L L NN+ L VS + L L+ +DL NP
Sbjct: 338 KSLPVYIFSG-APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 384
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 68.9 bits (161), Expect = 4e-11
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + L++ N++ V +F L LHL N I + + F +LT+L+ L L NQI
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L +F L L L L N + +++ F + +L++ LL+ + I+ P
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F YL S L+ L ++ L+GN
Sbjct: 498 -LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 67.3 bits (157), Expect = 1e-10
Identities = 48/130 (36%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Query: 68 NFLTIGPIFTQPAPFVNLRE---LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVA 124
NFL I P F+N LH+ N+ + +I +F GL L+ L+L +N L + A
Sbjct: 69 NFLNI----LYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRA 124
Query: 125 DNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSIL 184
D F G+ NL L D+N I+ + F L LK LIL +N IS L +FR A L+ L
Sbjct: 125 DTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR-FASLTHL 183
Query: 185 DLSDNPLTDL 194
D+ N + L
Sbjct: 184 DIRGNRIQKL 193
Score = 58.8 bits (136), Expect = 5e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N +LH++ N I+ + F L L L +NQI+ + +F L L L L+ N
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
+ L PE+F + +L+ L++ I+ + +P L+ L L NL K L F S
Sbjct: 437 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIF-SG 495
Query: 251 KRLKKLKLDGNQLSVI-VDNMFGRNRELHVLTLSRN 285
L +L L N+ + V + + + L + L N
Sbjct: 496 APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 56.0 bits (129), Expect = 3e-07
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 4/159 (2%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P+ N L+ N+ + + +F + L+L +N L ++ F GL L +LHL++
Sbjct: 57 PWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNN 116
Query: 141 NHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N ++ + ++TF + +L+ L N I + F L KL +L L+DN ++ L +F+
Sbjct: 117 NELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR 176
Query: 201 --DIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
+ HL I R L I + + R+ EL L +N
Sbjct: 177 FASLTHLDIRGNRIQKLPYIG--VLEHIGRVVELQLEDN 213
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)
Query: 1 MSSLVVYNTEAAG-TICPDECTC-TMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVV 58
+S +V Y T T CP C C T DL Q +IP + +HV
Sbjct: 326 LSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHV- 384
Query: 59 IIAAPPDRPNFLTIGPIFTQP-APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN 117
N +I + F L LH+ ++ + I F L NLR L L N
Sbjct: 385 ---------NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGN 435
Query: 118 NLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRM 177
+ + + F GL NL L+L++N I+++S+ TF + +L+ L L NN + +L +F
Sbjct: 436 QIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 495
Query: 178 LAKLSILDLSDN 189
A L+ L+L +N
Sbjct: 496 -APLARLNLRNN 506
Score = 51.2 bits (117), Expect = 9e-06
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N L+ +N + + TF + + +L L NN++ + F L+ L L L++N L
Sbjct: 60 NFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNEL 119
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L + F I++L + L++ I ++ + +L+ L L +NL +L D
Sbjct: 120 KILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFL-PDNIFRFA 178
Query: 252 RLKKLKLDGNQL 263
L L + GN++
Sbjct: 179 SLTHLDIRGNRI 190
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F GL NL+ L L +N + + A F + NL L+L++N +
Sbjct: 426 NLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLL 485
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + F L L L NN+ L VS + L L+ +DL NP
Sbjct: 486 KSLPVYIFSG-APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 532
Score = 44.8 bits (101), Expect = 8e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Query: 164 NNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIY 223
NN ++ L F + L L +N L ++ F + L+ L+ + +
Sbjct: 68 NNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTF 127
Query: 224 HLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLS 283
+ LE L NL KY+ F L +LK L L+ N +S + DN+F R L L +
Sbjct: 128 LGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF-RFASLTHLDIR 186
Query: 284 RNR 286
NR
Sbjct: 187 GNR 189
>AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33057 fis, clone TRACH1000144, weakly similar to
CHONDROADHERIN PRECURSOR. ).
Length = 469
Score = 68.9 bits (161), Expect = 4e-11
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + L++ N++ V +F L LHL N I + + F +LT+L+ L L NQI
Sbjct: 10 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 69
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L +F L L L L N + +++ F + +L++ LL+ + I+ P
Sbjct: 70 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 129
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F YL S L+ L ++ L+GN
Sbjct: 130 -LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 58.8 bits (136), Expect = 5e-08
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 131 INLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+N +LH++ N I+ + F L L L +NQI+ + +F L L L L+ N
Sbjct: 9 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 68
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
+ L PE+F + +L+ L++ I+ + +P L+ L L NL K L F S
Sbjct: 69 IERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIF-SG 127
Query: 251 KRLKKLKLDGNQLSVI-VDNMFGRNRELHVLTLSRN 285
L +L L N+ + V + + + L + L N
Sbjct: 128 APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 82 FVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN 141
F L LH+ ++ + I F L NLR L L N + + + F GL NL L+L++N
Sbjct: 32 FEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYN 91
Query: 142 HIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDN 189
I+++S+ TF + +L+ L L NN + +L +F A L+ L+L +N
Sbjct: 92 LIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-APLARLNLRNN 138
Score = 48.4 bits (110), Expect = 7e-05
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F GL NL+ L L +N + + A F + NL L+L++N +
Sbjct: 58 NLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLL 117
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ + F L L L NN+ L VS + L L+ +DL NP
Sbjct: 118 KSLPVYIFSG-APLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 164
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/183 (28%), Positives = 95/183 (51%), Gaps = 7/183 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR + + N+ + S+ L+ L+L +N LT V+ D L L L L++NH+
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLT-VLPDEICNLKKLETLSLNNNHL 97
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S TF L++LKTL L+ NQ+ L +L L L ++DLS N + + P+ ++Q
Sbjct: 98 RELPS-TFGQLSALKTLSLSGNQLGALPPQLC-SLRHLDVMDLSKNQIRSI-PDSVGELQ 154
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY-LTSDEFISLKRLKKLKLDGNQ 262
+ + + + +I+ +I PRL+ L L EN + + +S ++ L ++GN
Sbjct: 155 VIEL-NLNQNQISQISVKI-SCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNL 212
Query: 263 LSV 265
+
Sbjct: 213 FEI 215
Score = 40.3 bits (90), Expect = 0.018
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 7/132 (5%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
++L+T+ L+NN+I +L L L L L++N LT L P+ +++ L
Sbjct: 38 SNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-PDEICNLKKLETLSLNNNH 96
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
LR + + L L+ L L N L + SL+ L + L NQ+ I D++
Sbjct: 97 LRELPSTFGQL-SALKTLSLSGNQLGAL-PPQLCSLRHLDVMDLSKNQIRSIPDSV---- 150
Query: 275 RELHVLTLSRNR 286
EL V+ L+ N+
Sbjct: 151 GELQVIELNLNQ 162
Score = 39.1 bits (87), Expect = 0.041
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
L + L E P + +L +DLS NK+ P L+ K L+ L +++NKL L ++
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 416 --DLQRLEAIA 424
+L++LE ++
Sbjct: 81 ICNLKKLETLS 91
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 220 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 279
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 280 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 339
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 340 LNVSGNQLTTLEESVFHSVGNLETLILDSN 369
Score = 68.1 bits (159), Expect = 8e-11
Identities = 68/300 (22%), Positives = 131/300 (43%), Gaps = 2/300 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L+L N + ++ D F +L EL L+ N + + F +L +L+TL L +N++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ +F L+ L+ LD+S+N + L +F+D+ +L+ + L I+ + + + L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E+L L + + ++ L L L+L ++ I D F R L VL +S
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLD 253
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
I+H + +V L+ +N S N + E +++ ++L
Sbjct: 254 TMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELL- 311
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L L + F +L L++S N+L+ + L+ L + N L
Sbjct: 312 RLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L I + + + + F L NL+ L + N+L + F GL +L +L L+ ++
Sbjct: 144 NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNL 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 204 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 263
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 264 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGG 321
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 322 QLAVVEPYAFRGLNYLRVLNVSGNQ 346
Score = 64.5 bits (150), Expect = 9e-10
Identities = 45/155 (29%), Positives = 72/155 (46%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F +L EL + + V ++ +F L NLR L L N L + F GL NLT+L +
Sbjct: 92 ASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDIS 151
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I + F+ L +LK+L + +N + + R F L L L L LT + E
Sbjct: 152 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 211
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+ L + + R + I + + RL+ L++
Sbjct: 212 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 60.5 bits (140), Expect = 2e-08
Identities = 66/308 (21%), Positives = 121/308 (39%), Gaps = 4/308 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T + L L N+I TL F L L+L++N ++ + P F ++ +LR R
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L+ I ++ + L +LD+ EN L F L LK L++ N L I F
Sbjct: 131 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 190
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L LTL + + H I+ +F + LK + S
Sbjct: 191 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLY-RLKVLEIS-- 247
Query: 335 NLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ P L+ + + + + + +L +P + +L L+LS+N +S +L
Sbjct: 248 HWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSML 307
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLN 453
+ LQ + + +L + + L + +N+ N + S + + + T +L+
Sbjct: 308 HELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 367
Query: 454 STIRVLKC 461
S C
Sbjct: 368 SNPLACDC 375
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/173 (26%), Positives = 76/173 (43%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L + + + ++ Q F +L L L N +++V F L NL L L N ++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+ F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F + L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+C L I T+ + L L L + F L RLK L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 263 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 322
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 323 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 287 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 346
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 347 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 405
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 406 EFKDFPDVLLPNYFTCRRARIR 427
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 220 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 279
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 280 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 339
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 340 LNVSGNQLTTLEESVFHSVGNLETLILDSN 369
Score = 65.7 bits (153), Expect = 4e-10
Identities = 67/300 (22%), Positives = 130/300 (43%), Gaps = 2/300 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L+L N + ++ D F +L EL L+ N + + F +L +L+TL L +N++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ +F L+ L+ D+S+N + L +F+D+ +L+ + L I+ + + + L
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E+L L + + ++ L L L+L ++ I D F R L VL +S
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLD 253
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
I+H + +V L+ +N S N + E +++ ++L
Sbjct: 254 TMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELL- 311
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L L + F +L L++S N+L+ + L+ L + N L
Sbjct: 312 RLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 65.3 bits (152), Expect = 5e-10
Identities = 55/205 (26%), Positives = 94/205 (45%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL + I + + + + F L NL+ L + N+L + F GL +L +L L+ ++
Sbjct: 144 NLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNL 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 204 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 263
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 264 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGG 321
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 322 QLAVVEPYAFRGLNYLRVLNVSGNQ 346
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/155 (28%), Positives = 71/155 (45%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F +L EL + + V ++ +F L NLR L L N L + F GL NLT+ +
Sbjct: 92 ASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKQDIS 151
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I + F+ L +LK+L + +N + + R F L L L L LT + E
Sbjct: 152 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 211
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+ L + + R + I + + RL+ L++
Sbjct: 212 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 58.0 bits (134), Expect = 8e-08
Identities = 44/173 (25%), Positives = 75/173 (43%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L + + + ++ Q F +L L L N +++V F L NL L L N ++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+ F L++L ++ N+I L+ +F+ L L L++ DN L ++ F + L
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+C L I T+ + L L L + F L RLK L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 263 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 322
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 323 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 287 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 346
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 347 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 405
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 406 EFKDFPDVLLPNYFTCRRARIR 427
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/220 (24%), Positives = 105/220 (47%), Gaps = 3/220 (1%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFW 104
+I +DYM +D+H + D F+ ++L +L + N+ ++ +
Sbjct: 142 VILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSG---LLSLEQLTLEKCNLTAVPTEALS 198
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L++L L+L H N+ ++ F+ L +L L +D+ + M + +L +L + N
Sbjct: 199 HLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTN 258
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
+ST+ F+ L L+ L+LS NP++ + +F D+ L+ LR I +
Sbjct: 259 TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQ 318
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
+ L L++ +NL + L + F S + L+ L ++ N L+
Sbjct: 319 GLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 62.1 bits (144), Expect = 5e-09
Identities = 71/301 (23%), Positives = 120/301 (39%), Gaps = 22/301 (7%)
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRR 217
K L L+ N++ ++ F L +DLSDN + ++ P F ++ +LR + + L+
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 218 INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
+ ++ + L +LD+ EN L F L LK L++ N L I F L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 278 HVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDR---------FHLQ----TFAPVVD 324
LTL + + H I+ FHL+ + P++D
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 325 SLKTINFSGNNLP-LNEIAIVLQILPEI---HGVGLANLSLQEIP-----QNFFTYNEHL 375
+ + G NL L+ L +P + H V L +L+L P F+ L
Sbjct: 240 MMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L + +L +FL+ L++S N L+TL E A+ +++ N C
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLAC 359
Query: 436 D 436
D
Sbjct: 360 D 360
Score = 60.5 bits (140), Expect = 2e-08
Identities = 64/306 (20%), Positives = 126/306 (41%), Gaps = 6/306 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ + L + + + S+ F L ++L+ N + +V F L NL L L N
Sbjct: 57 IETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNR 116
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ + F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F +
Sbjct: 117 LKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L +C L + T+ + L L L + F L LK L++D
Sbjct: 177 LSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWP 236
Query: 263 L--SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L + ++++G N L L+++ ++S+N I F+
Sbjct: 237 LLDMMPANSLYGLN--LTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFS 294
Query: 321 PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDL 380
++ L+ ++ G L E Q L + + ++ L+ + +N F+ L L +
Sbjct: 295 DLI-RLQELHIVGAQLRTIE-PHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSI 352
Query: 381 SWNKLS 386
+ N L+
Sbjct: 353 NNNPLA 358
>AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 479
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 112 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 171
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 172 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 231
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 232 LNVSGNQLTTLEESVFHSVGNLETLILDSN 261
Score = 68.1 bits (159), Expect = 8e-11
Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L I + + + + F L NL+ L + N+L + F GL +L +L L+ ++
Sbjct: 36 NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNL 95
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 96 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 155
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 156 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGG 213
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 214 QLAVVEPYAFRGLNYLRVLNVSGNQ 238
Score = 61.7 bits (143), Expect = 7e-09
Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 2/203 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L + ++++ I +F GL +L L L NLTS+ + L L L L H +I
Sbjct: 60 NLKSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 119
Query: 144 EQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +F+ L LK L +++ + T+ L L+ L ++ LT + + +
Sbjct: 120 NAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHL 178
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR + I + H + RL+E+ L + F L L+ L + GNQ
Sbjct: 179 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 238
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
L+ + +++F L L L N
Sbjct: 239 LTTLEESVFHSVGNLETLILDSN 261
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 155 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 214
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 215 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 263
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/133 (29%), Positives = 61/133 (45%)
Query: 102 SFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLI 161
+F L NLR L L N L + F GL NLT+L + N I + F+ L +LK+L
Sbjct: 6 AFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLE 65
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
+ +N + + R F L L L L LT + E + L + + R + I
Sbjct: 66 VGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDY 125
Query: 222 IYHLVPRLEELDL 234
+ + RL+ L++
Sbjct: 126 SFKRLYRLKVLEI 138
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/269 (20%), Positives = 102/269 (37%), Gaps = 4/269 (1%)
Query: 194 LNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ P F ++ +LR R L+ I ++ + L +LD+ EN L F L L
Sbjct: 2 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 61
Query: 254 KKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDR 313
K L++ N L I F L LTL + + H I+
Sbjct: 62 KSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINA 121
Query: 314 FHLQTFAPVVDSLKTINFSGNNLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYN 372
+F + LK + S + P L+ + + + + + +L +P +
Sbjct: 122 IRDYSFKRLY-RLKVLEIS--HWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHL 178
Query: 373 EHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNN 432
+L L+LS+N +S +L + LQ + + +L + + L + +N+ N
Sbjct: 179 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 238
Query: 433 WHCDQCSASNMLLYMTTTVLNSTIRVLKC 461
+ S + + + T +L+S C
Sbjct: 239 LTTLEESVFHSVGNLETLILDSNPLACDC 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 179 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 238
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 239 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 297
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 298 EFKDFPDVLLPNYFTCRRARIR 319
>AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 469
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 69 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 128
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 129 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 188
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 189 LNVSGNQLTTLEESVFHSVGNLETLILDSN 218
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 2/203 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L + ++++ I +F GL +L L L NLTS+ + L L L L H +I
Sbjct: 17 NLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 76
Query: 144 EQMSSETFRHLTSLKTLILAN-NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ +F+ L LK L +++ + T+ L L+ L ++ LT + + +
Sbjct: 77 NAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHL 135
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
+LR + I + H + RL+E+ L + F L L+ L + GNQ
Sbjct: 136 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 195
Query: 263 LSVIVDNMFGRNRELHVLTLSRN 285
L+ + +++F L L L N
Sbjct: 196 LTTLEESVFHSVGNLETLILDSN 218
Score = 62.5 bits (145), Expect = 4e-09
Identities = 52/188 (27%), Positives = 87/188 (46%), Gaps = 4/188 (2%)
Query: 101 FSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTL 160
+ F L NL+ L + N+L + F GL +L +L L+ ++ + +E HL L L
Sbjct: 10 YMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVL 69
Query: 161 ILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDIQHLRIFKCRRCLLRRI- 218
L + I+ + F+ L +L +L++S P D + P + +L C L +
Sbjct: 70 RLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVP 128
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+ HLV L L+L N + L RL++++L G QL+V+ F L
Sbjct: 129 YLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLR 187
Query: 279 VLTLSRNR 286
VL +S N+
Sbjct: 188 VLNVSGNQ 195
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 112 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 171
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 172 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 220
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 136 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 195
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 196 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 254
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 255 EFKDFPDVLLPNYFTCRRARIR 276
Score = 33.1 bits (72), Expect = 2.7
Identities = 25/94 (26%), Positives = 40/94 (42%)
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
N+I L+ +F+ L L L++ DN L ++ F + L +C L I T+
Sbjct: 2 NKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALS 61
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+ L L L + F L RLK L++
Sbjct: 62 HLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 95
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 220 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 279
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 280 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 339
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 340 LNVSGNQLTTLEESVFHSVGNLETLILDSN 369
Score = 68.1 bits (159), Expect = 8e-11
Identities = 68/300 (22%), Positives = 131/300 (43%), Gaps = 2/300 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L+L N + ++ D F +L EL L+ N + + F +L +L+TL L +N++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ +F L+ L+ LD+S+N + L +F+D+ +L+ + L I+ + + + L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E+L L + + ++ L L L+L ++ I D F R L VL +S
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLD 253
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
I+H + +V L+ +N S N + E +++ ++L
Sbjct: 254 TMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELL- 311
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L L + F +L L++S N+L+ + L+ L + N L
Sbjct: 312 RLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L I + + + + F L NL+ L + N+L + F GL +L +L L+ ++
Sbjct: 144 NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNL 203
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 204 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 263
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 264 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGG 321
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 322 QLAVVEPYAFRGLNYLRVLNVSGNQ 346
Score = 64.5 bits (150), Expect = 9e-10
Identities = 45/155 (29%), Positives = 72/155 (46%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F +L EL + + V ++ +F L NLR L L N L + F GL NLT+L +
Sbjct: 92 ASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDIS 151
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I + F+ L +LK+L + +N + + R F L L L L LT + E
Sbjct: 152 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 211
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+ L + + R + I + + RL+ L++
Sbjct: 212 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 60.5 bits (140), Expect = 2e-08
Identities = 66/308 (21%), Positives = 121/308 (39%), Gaps = 4/308 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T + L L N+I TL F L L+L++N ++ + P F ++ +LR R
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L+ I ++ + L +LD+ EN L F L LK L++ N L I F
Sbjct: 131 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 190
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L LTL + + H I+ +F + LK + S
Sbjct: 191 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLY-RLKVLEIS-- 247
Query: 335 NLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ P L+ + + + + + +L +P + +L L+LS+N +S +L
Sbjct: 248 HWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSML 307
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLN 453
+ LQ + + +L + + L + +N+ N + S + + + T +L+
Sbjct: 308 HELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 367
Query: 454 STIRVLKC 461
S C
Sbjct: 368 SNPLACDC 375
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/173 (26%), Positives = 76/173 (43%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L + + + ++ Q F +L L L N +++V F L NL L L N ++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+ F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F + L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+C L I T+ + L L L + F L RLK L++
Sbjct: 194 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 263 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 322
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 323 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 287 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 346
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 347 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 405
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 406 EFKDFPDVLLPNYFTCRRARIR 427
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 68.5 bits (160), Expect = 6e-11
Identities = 42/150 (28%), Positives = 70/150 (46%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L + + N+ +I +SF L L+VL ++H + N +NLT L + H ++ +
Sbjct: 177 LRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVP 236
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
RHL L+ L L+ N IST+ + L +L + L L + P F+ + +LR+
Sbjct: 237 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRV 296
Query: 208 FKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + ++H V LE L L N
Sbjct: 297 LNVSGNQLTTLEESVFHSVGNLETLILDSN 326
Score = 68.1 bits (159), Expect = 8e-11
Identities = 68/300 (22%), Positives = 131/300 (43%), Gaps = 2/300 (0%)
Query: 110 RVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQIST 169
R+L+L N + ++ D F +L EL L+ N + + F +L +L+TL L +N++
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 170 LVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRL 229
+ +F L+ L+ LD+S+N + L +F+D+ +L+ + L I+ + + + L
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 230 EELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXX 289
E+L L + + ++ L L L+L ++ I D F R L VL +S
Sbjct: 151 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLD 210
Query: 290 XXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILP 349
I+H + +V L+ +N S N + E +++ ++L
Sbjct: 211 TMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELL- 268
Query: 350 EIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKL 409
+ + L L + F +L L++S N+L+ + L+ L + N L
Sbjct: 269 RLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 328
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 4/205 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL +L I + + + + F L NL+ L + N+L + F GL +L +L L+ ++
Sbjct: 101 NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNL 160
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD-LNPEVFKDI 202
+ +E HL L L L + I+ + F+ L +L +L++S P D + P +
Sbjct: 161 TSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL 220
Query: 203 QHLRIFKCRRCLLRRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
+L C L + + HLV L L+L N + L RL++++L G
Sbjct: 221 -NLTSLSITHCNLTAVPYLAVRHLV-YLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGG 278
Query: 262 QLSVIVDNMFGRNRELHVLTLSRNR 286
QL+V+ F L VL +S N+
Sbjct: 279 QLAVVEPYAFRGLNYLRVLNVSGNQ 303
Score = 64.5 bits (150), Expect = 9e-10
Identities = 45/155 (29%), Positives = 72/155 (46%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
A F +L EL + + V ++ +F L NLR L L N L + F GL NLT+L +
Sbjct: 49 ASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDIS 108
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVF 199
N I + F+ L +LK+L + +N + + R F L L L L LT + E
Sbjct: 109 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 168
Query: 200 KDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDL 234
+ L + + R + I + + RL+ L++
Sbjct: 169 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 203
Score = 60.5 bits (140), Expect = 2e-08
Identities = 66/308 (21%), Positives = 121/308 (39%), Gaps = 4/308 (1%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
T + L L N+I TL F L L+L++N ++ + P F ++ +LR R
Sbjct: 28 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 87
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
L+ I ++ + L +LD+ EN L F L LK L++ N L I F
Sbjct: 88 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 147
Query: 275 RELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
L LTL + + H I+ +F + LK + S
Sbjct: 148 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLY-RLKVLEIS-- 204
Query: 335 NLP-LNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLL 393
+ P L+ + + + + + +L +P + +L L+LS+N +S +L
Sbjct: 205 HWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSML 264
Query: 394 SKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLN 453
+ LQ + + +L + + L + +N+ N + S + + + T +L+
Sbjct: 265 HELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 324
Query: 454 STIRVLKC 461
S C
Sbjct: 325 SNPLACDC 332
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/173 (26%), Positives = 76/173 (43%)
Query: 86 RELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQ 145
R L + + + ++ Q F +L L L N +++V F L NL L L N ++
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 146 MSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+ F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F + L
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 206 RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKL 258
+C L I T+ + L L L + F L RLK L++
Sbjct: 151 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 203
Score = 57.6 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+NL L I + N+ ++ + L LR LNL++N ++++ L+ L E+ L
Sbjct: 220 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 279
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ + FR L L+ L ++ NQ++TL +F + L L L NPL
Sbjct: 280 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 328
Score = 37.5 bits (83), Expect = 0.12
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
V LR L++ + + +I L L+ + L L V FRGL L L++ N
Sbjct: 244 VYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQ 303
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEV---- 198
+ + F + +L+TLIL +N ++ RL + + L+ + T PE
Sbjct: 304 LTTLEESVFHSVGNLETLILDSNPLA-CDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGK 362
Query: 199 -FKDIQHLRI---FKCRRCLLR 216
FKD + + F CRR +R
Sbjct: 363 EFKDFPDVLLPNYFTCRRARIR 384
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/278 (25%), Positives = 117/278 (42%), Gaps = 8/278 (2%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ + +
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L L LDL+ N L + P + + L+ ++ I + + P L+ +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
+N +++ F L +L L L+G ++ G L +LTL+R
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG-TTSLEILTLTRAGIRLLPS 206
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI-AIVLQILPEI 351
++SHN+I+ L+ I N + EI A L +
Sbjct: 207 GMCQQLPRLRVLELSHNQIEEL---PSLHRCQKLEEIGLQHNR--IWEIGADTFSQLSSL 261
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFP 389
+ L+ +++ I F+ LV LDL+ N+L+ P
Sbjct: 262 QALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP 299
Score = 62.9 bits (146), Expect = 3e-09
Identities = 65/275 (23%), Positives = 110/275 (40%), Gaps = 6/275 (2%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N++ ++ F HL L+ L L+ N +S + + F L L IL L +N L + E
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ L+ L+ I L RL+EL N K + F+ L+ +
Sbjct: 90 ALWELPSLQSLDLNYNKLQEFPVAIRTL-GRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 148
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
N + + + F +LH L+L+ ++ I R
Sbjct: 149 FYDNPIQFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPS 206
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
+ L+ + S N + E L ++ +GL + + EI + F+ L A
Sbjct: 207 GMCQQLPRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 263
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
LDLSWN + + S L +LD++ N+L TL
Sbjct: 264 LDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTL 298
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 212 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 269
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 270 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 311
Score = 58.4 bits (135), Expect = 6e-08
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL N+N+ +I + +F G L+ ++ N + V F+ L L L L + ++
Sbjct: 120 LQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMD 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ TSL+ L L I L S + + L +L +L+LS N + +L P + + Q
Sbjct: 179 IQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHR-CQK 236
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L + + I + + L+ LDL N + + + F +L L KL L NQL+
Sbjct: 237 LEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLT 296
Query: 265 VI 266
+
Sbjct: 297 TL 298
Score = 44.8 bits (101), Expect = 8e-04
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 11/245 (4%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+N+ + F L+ L L L+ N+L+ + F GL +L L L +N + + +E
Sbjct: 33 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 92
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L SL++L L N++ + R L +L L +N + + + F L+
Sbjct: 93 ELPSLQSLDLNYNKLQEFPVAI-RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 151
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK---RLKKLKLDGNQLSVIVDN 269
++ + + +P+L L L + EF LK L+ L L + ++
Sbjct: 152 NPIQFVGRSAFQYLPKLHTLSLN----GAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 207
Query: 270 MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTI 329
M + L VL LS N+ + HN+I TF+ + SL+ +
Sbjct: 208 MCQQLPRLRVLELSHNQ--IEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQ-LSSLQAL 264
Query: 330 NFSGN 334
+ S N
Sbjct: 265 DLSWN 269
Score = 32.7 bits (71), Expect = 3.5
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
L+ L IP F+ L L L N+L P + L + LQ LD+++NKLQ
Sbjct: 54 LSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVA 113
Query: 416 DLQRLEAIAEVNLMKNN 432
++ L + E+ NN
Sbjct: 114 -IRTLGRLQELGFHNNN 129
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/220 (24%), Positives = 105/220 (47%), Gaps = 3/220 (1%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFW 104
+I +DYM +D+H + D F+ ++L +L + N+ ++ +
Sbjct: 142 VILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSG---LLSLEQLTLEKCNLTAVPTEALS 198
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L++L L+L H N+ ++ F+ L +L L +D+ + M + +L +L + N
Sbjct: 199 HLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTN 258
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
+ST+ F+ L L+ L+LS NP++ + +F D+ L+ LR I +
Sbjct: 259 TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQ 318
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
+ L L++ +NL + L + F S + L+ L ++ N L+
Sbjct: 319 GLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 62.1 bits (144), Expect = 5e-09
Identities = 71/301 (23%), Positives = 120/301 (39%), Gaps = 22/301 (7%)
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRR 217
K L L+ N++ ++ F L +DLSDN + ++ P F ++ +LR + + L+
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 218 INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
+ ++ + L +LD+ EN L F L LK L++ N L I F L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 278 HVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDR---------FHLQ----TFAPVVD 324
LTL + + H I+ FHL+ + P++D
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 325 SLKTINFSGNNLP-LNEIAIVLQILPEI---HGVGLANLSLQEIP-----QNFFTYNEHL 375
+ + G NL L+ L +P + H V L +L+L P F+ L
Sbjct: 240 MMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L + +L +FL+ L++S N L+TL E A+ +++ N C
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLAC 359
Query: 436 D 436
D
Sbjct: 360 D 360
Score = 60.5 bits (140), Expect = 2e-08
Identities = 64/306 (20%), Positives = 126/306 (41%), Gaps = 6/306 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ + L + + + S+ F L ++L+ N + +V F L NL L L N
Sbjct: 57 IETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNR 116
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ + F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F +
Sbjct: 117 LKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L +C L + T+ + L L L + F L LK L++D
Sbjct: 177 LSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWP 236
Query: 263 L--SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L + ++++G N L L+++ ++S+N I F+
Sbjct: 237 LLDMMPANSLYGLN--LTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFS 294
Query: 321 PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDL 380
++ L+ ++ G L E Q L + + ++ L+ + +N F+ L L +
Sbjct: 295 DLI-RLQELHIVGAQLRTIE-PHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSI 352
Query: 381 SWNKLS 386
+ N L+
Sbjct: 353 NNNPLA 358
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/183 (28%), Positives = 95/183 (51%), Gaps = 7/183 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR + + N+ + S+ L+ L+L +N LT V+ D L L L L++NH+
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLT-VLPDEICNLKKLETLSLNNNHL 97
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S TF L++LKTL L+ NQ+ L +L L L ++DLS N + + P+ ++Q
Sbjct: 98 RELPS-TFGQLSALKTLSLSGNQLGALPPQLC-SLRHLDVMDLSKNQIRSI-PDSVGELQ 154
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY-LTSDEFISLKRLKKLKLDGNQ 262
+ + + + +I+ +I PRL+ L L EN + + +S ++ L ++GN
Sbjct: 155 VIEL-NLNQNQISQISVKI-SCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNL 212
Query: 263 LSV 265
+
Sbjct: 213 FEI 215
Score = 40.3 bits (90), Expect = 0.018
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 7/132 (5%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
++L+T+ L+NN+I +L L L L L++N LT L P+ +++ L
Sbjct: 38 SNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-PDEICNLKKLETLSLNNNH 96
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
LR + + L L+ L L N L + SL+ L + L NQ+ I D++
Sbjct: 97 LRELPSTFGQL-SALKTLSLSGNQLGAL-PPQLCSLRHLDVMDLSKNQIRSIPDSV---- 150
Query: 275 RELHVLTLSRNR 286
EL V+ L+ N+
Sbjct: 151 GELQVIELNLNQ 162
Score = 39.1 bits (87), Expect = 0.041
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
L + L E P + +L +DLS NK+ P L+ K L+ L +++NKL L ++
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 416 --DLQRLEAIA 424
+L++LE ++
Sbjct: 81 ICNLKKLETLS 91
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/183 (28%), Positives = 95/183 (51%), Gaps = 7/183 (3%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR + + N+ + S+ L+ L+L +N LT V+ D L L L L++NH+
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLT-VLPDEICNLKKLETLSLNNNHL 97
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
++ S TF L++LKTL L+ NQ+ L +L L L ++DLS N + + P+ ++Q
Sbjct: 98 RELPS-TFGQLSALKTLSLSGNQLGALPPQLC-SLRHLDVMDLSKNQIRSI-PDSVGELQ 154
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKY-LTSDEFISLKRLKKLKLDGNQ 262
+ + + + +I+ +I PRL+ L L EN + + +S ++ L ++GN
Sbjct: 155 VIEL-NLNQNQISQISVKI-SCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNL 212
Query: 263 LSV 265
+
Sbjct: 213 FEI 215
Score = 40.3 bits (90), Expect = 0.018
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 7/132 (5%)
Query: 155 TSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCL 214
++L+T+ L+NN+I +L L L L L++N LT L P+ +++ L
Sbjct: 38 SNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-PDEICNLKKLETLSLNNNH 96
Query: 215 LRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRN 274
LR + + L L+ L L N L + SL+ L + L NQ+ I D++
Sbjct: 97 LRELPSTFGQL-SALKTLSLSGNQLGAL-PPQLCSLRHLDVMDLSKNQIRSIPDSV---- 150
Query: 275 RELHVLTLSRNR 286
EL V+ L+ N+
Sbjct: 151 GELQVIELNLNQ 162
Score = 39.1 bits (87), Expect = 0.041
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
L + L E P + +L +DLS NK+ P L+ K L+ L +++NKL L ++
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 416 --DLQRLEAIA 424
+L++LE ++
Sbjct: 81 ICNLKKLETLS 91
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 53/220 (24%), Positives = 105/220 (47%), Gaps = 3/220 (1%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRPNFLTIGPIFTQPAPFVNLRELHIVNSNVPSIGQFSFW 104
+I +DYM +D+H + D F+ ++L +L + N+ ++ +
Sbjct: 142 VILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSG---LLSLEQLTLEKCNLTAVPTEALS 198
Query: 105 GLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILAN 164
L++L L+L H N+ ++ F+ L +L L +D+ + M + +L +L + N
Sbjct: 199 HLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTN 258
Query: 165 NQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYH 224
+ST+ F+ L L+ L+LS NP++ + +F D+ L+ LR I +
Sbjct: 259 TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQ 318
Query: 225 LVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
+ L L++ +NL + L + F S + L+ L ++ N L+
Sbjct: 319 GLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 62.1 bits (144), Expect = 5e-09
Identities = 71/301 (23%), Positives = 120/301 (39%), Gaps = 22/301 (7%)
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRR 217
K L L+ N++ ++ F L +DLSDN + ++ P F ++ +LR + + L+
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 218 INTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNREL 277
+ ++ + L +LD+ EN L F L LK L++ N L I F L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 278 HVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDR---------FHLQ----TFAPVVD 324
LTL + + H I+ FHL+ + P++D
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 325 SLKTINFSGNNLP-LNEIAIVLQILPEI---HGVGLANLSLQEIP-----QNFFTYNEHL 375
+ + G NL L+ L +P + H V L +L+L P F+ L
Sbjct: 240 MMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 376 VALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
L + +L +FL+ L++S N L+TL E A+ +++ N C
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLAC 359
Query: 436 D 436
D
Sbjct: 360 D 360
Score = 60.5 bits (140), Expect = 2e-08
Identities = 64/306 (20%), Positives = 126/306 (41%), Gaps = 6/306 (1%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
+ + L + + + S+ F L ++L+ N + +V F L NL L L N
Sbjct: 57 IETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNR 116
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++ + F L++L L ++ N+I L+ +F+ L L L++ DN L ++ F +
Sbjct: 117 LKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L +C L + T+ + L L L + F L LK L++D
Sbjct: 177 LSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWP 236
Query: 263 L--SVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFA 320
L + ++++G N L L+++ ++S+N I F+
Sbjct: 237 LLDMMPANSLYGLN--LTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFS 294
Query: 321 PVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDL 380
++ L+ ++ G L E Q L + + ++ L+ + +N F+ L L +
Sbjct: 295 DLI-RLQELHIVGAQLRTIE-PHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSI 352
Query: 381 SWNKLS 386
+ N L+
Sbjct: 353 NNNPLA 358
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/278 (25%), Positives = 117/278 (42%), Gaps = 8/278 (2%)
Query: 113 NLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVS 172
+L+ NNLT + F L L EL L NH+ + + F L SLK L+L NNQ+ + +
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 173 RLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEEL 232
L L LDL+ N L + P + + L+ ++ I + + P L+ +
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 233 DLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXX 292
+N +++ F L +L L L+G ++ G L +LTL+R
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG-TTSLEILTLTRAGIRLLPS 206
Query: 293 XXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEI-AIVLQILPEI 351
++SHN+I+ L+ I N + EI A L +
Sbjct: 207 GMCQQLPRLRVLELSHNQIEEL---PSLHRCQKLEEIGLQHNR--IWEIGADTFSQLSSL 261
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFP 389
+ L+ +++ I F+ LV LDL+ N+L+ P
Sbjct: 262 QALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP 299
Score = 62.9 bits (146), Expect = 3e-09
Identities = 65/275 (23%), Positives = 110/275 (40%), Gaps = 6/275 (2%)
Query: 138 LDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
L N++ ++ F HL L+ L L+ N +S + + F L L IL L +N L + E
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 198 VFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLK 257
++ L+ L+ I L RL+EL N K + F+ L+ +
Sbjct: 90 ALWELPSLQSLDLNYNKLQEFPVAIRTL-GRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 148
Query: 258 LDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQ 317
N + + + F +LH L+L+ ++ I R
Sbjct: 149 FYDNPIQFVGRSAFQYLPKLHTLSLN-GAMDIQEFPDLKGTTSLEILTLTRAGI-RLLPS 206
Query: 318 TFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
+ L+ + S N + E L ++ +GL + + EI + F+ L A
Sbjct: 207 GMCQQLPRLRVLELSHNQI---EELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 263
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTL 412
LDLSWN + + S L +LD++ N+L TL
Sbjct: 264 LDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTL 298
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 106 LQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN 165
L LRVL L+HN + + + L E+ L HN I ++ ++TF L+SL+ L L+ N
Sbjct: 212 LPRLRVLELSHNQIEEL--PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 269
Query: 166 QISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRI 207
I ++ F L L LDL+DN LT L + HL++
Sbjct: 270 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKL 311
Score = 58.4 bits (135), Expect = 6e-08
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+EL N+N+ +I + +F G L+ ++ N + V F+ L L L L + ++
Sbjct: 120 LQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMD 178
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
+ TSL+ L L I L S + + L +L +L+LS N + +L P + + Q
Sbjct: 179 IQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHR-CQK 236
Query: 205 LRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLS 264
L + + I + + L+ LDL N + + + F +L L KL L NQL+
Sbjct: 237 LEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLT 296
Query: 265 VI 266
+
Sbjct: 297 TL 298
Score = 44.8 bits (101), Expect = 8e-04
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 11/245 (4%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFR 152
+N+ + F L+ L L L+ N+L+ + F GL +L L L +N + + +E
Sbjct: 33 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 92
Query: 153 HLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRR 212
L SL++L L N++ + R L +L L +N + + + F L+
Sbjct: 93 ELPSLQSLDLNYNKLQEFPVAI-RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 151
Query: 213 CLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK---RLKKLKLDGNQLSVIVDN 269
++ + + +P+L L L + EF LK L+ L L + ++
Sbjct: 152 NPIQFVGRSAFQYLPKLHTLSLN----GAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 207
Query: 270 MFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTI 329
M + L VL LS N+ + HN+I TF+ + SL+ +
Sbjct: 208 MCQQLPRLRVLELSHNQ--IEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQ-LSSLQAL 264
Query: 330 NFSGN 334
+ S N
Sbjct: 265 DLSWN 269
Score = 32.7 bits (71), Expect = 3.5
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 356 LANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQ 415
L+ L IP F+ L L L N+L P + L + LQ LD+++NKLQ
Sbjct: 54 LSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVA 113
Query: 416 DLQRLEAIAEVNLMKNN 432
++ L + E+ NN
Sbjct: 114 -IRTLGRLQELGFHNNN 129
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/154 (25%), Positives = 71/154 (46%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL++LRVL L N ++++ F+ L L L L+ NH+
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L L L+ NQI + + FR + L L N ++ + F+ ++
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + R++ ++ +P+L L N
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 62.5 bits (145), Expect = 4e-09
Identities = 39/126 (30%), Positives = 61/126 (48%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L L +L L +N ++ + F+D++ L + R L+
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ +L LDL EN + + F +K L+LD NQ+S I D F R+L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 180 LTLNNN 185
Score = 62.5 bits (145), Expect = 4e-09
Identities = 33/103 (32%), Positives = 56/103 (54%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L LR +N ++N +T + F G + E+ L N +E + + F+ L SLKTL+L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N+I+ + + F L+ + +L L DN +T + P F + L
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 656
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL +L L L N I + F+ L L+ L L N
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ LF AKL LDLS+N + + + F+ ++ + + I + +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N L+ F + +L+ +L N L
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/106 (33%), Positives = 59/106 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR+++ N+ + I + +F G + + LT N L +V F+GL +L L L N I
Sbjct: 560 LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRIT 619
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L+S++ L L +NQI+T+ F L LS L+L NP
Sbjct: 620 CVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 665
Score = 59.7 bits (138), Expect = 3e-08
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + + +F GL++L L L N +T + F GL +L L L+
Sbjct: 321 SPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLN 380
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I + + F+ L +L L L +N++ T+ F L + + L+ NP + D + +
Sbjct: 381 ANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKW 440
Query: 199 FKDIQH 204
D H
Sbjct: 441 LADYLH 446
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/122 (27%), Positives = 64/122 (52%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + I +F + LR ++L++N ++ + D F+GL +L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
++ F L SL+ L+L N+I+ L F+ L L++L L DN L + F ++
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 205 LR 206
++
Sbjct: 422 IQ 423
Score = 55.2 bits (127), Expect = 6e-07
Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 14/284 (4%)
Query: 160 LILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
L L NN+ + L + +F+ L +L ++ S+N +TD+ F+ + L +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+++ + L+ L L N + +D FI L ++ L L NQ++ + F L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAPVVD-SLKTINFSGNN- 335
L L N ++ N + + + P+ D +++ N
Sbjct: 658 TLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGND 717
Query: 336 ----LPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
PL+ L + V +N L+ +P+ + L L N+ + P K
Sbjct: 718 DNSCSPLSRCPTECTCLDTV--VRCSNKGLKVLPKGI---PRDVTELYLDGNQFTLVP-K 771
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
LS K L +D+S+N++ TLS Q + + + L N C
Sbjct: 772 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 815
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/107 (29%), Positives = 50/107 (46%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + +++ + F G L L+L+ N + ++ FRG +++ L LD+N I
Sbjct: 105 LERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQIS 164
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+ L F + KL L N L
Sbjct: 165 CIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/133 (24%), Positives = 63/133 (47%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + + F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 300 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 359
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L LF L L +L L+ N + L + F+D+ +L + L+ I + +
Sbjct: 360 ITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPL 419
Query: 227 PRLEELDLGENLF 239
++ + L +N F
Sbjct: 420 RAIQTMHLAQNPF 432
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/129 (24%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQIS L F+ L L+ L L N +T
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
+L +F+ + L++ + + + + L L L +N + + F L+
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 253 LKKLKLDGN 261
++ + L N
Sbjct: 422 IQTMHLAQN 430
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
++L +++L++N ++++ +F + L L L +N + + TF L SL+ L L N
Sbjct: 777 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGND 836
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKD 201
IS + F L+ LS L + NPL D N + D
Sbjct: 837 ISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 872
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F L+ L+ L+L N++S I F +EL L L+R
Sbjct: 53 IPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNR 112
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N D+S N+I + F VD +K + N + E
Sbjct: 113 NHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVD-IKNLQLDYNQISCIEDG-A 170
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ + F + L L N L
Sbjct: 171 FRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 35/153 (22%), Positives = 60/153 (39%), Gaps = 1/153 (0%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
LDL+ N +T + F ++HLR+ + + I + + LE L L N +
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
F+ +L +L L NQ+ I F ++ L L N+
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
+++N I R + +F + L+T NNL
Sbjct: 180 LTLNNNNITRLSVASFNH-MPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/158 (26%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 319 FAPVVDSLKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
F+P L+ I+ S N + +E+A Q L ++ + L + E+P++ F L
Sbjct: 320 FSPY-KKLRRIDLSNNQI--SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQ 437
L L+ NK++ L L + NKLQT+++ L AI ++L +N + CD
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICD- 435
Query: 438 CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
C + Y+ T + ++ +C SP RL G +
Sbjct: 436 CHLKWLADYLHTNPIETS--GARCTSPRRLANKRIGQI 471
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/124 (25%), Positives = 53/124 (42%)
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
L N I + F KL +DLS+N +++L P+ F+ ++ L + +
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
++ + L+ L L N L D F L L L L N+L I F R + +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 282 LSRN 285
L++N
Sbjct: 427 LAQN 430
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP ECTC T V C + ++++P + RDV + + N T+ P
Sbjct: 727 CPTECTCL---------DTVVRCSNKGLKVLPKG-IPRDVTELYLDG-----NQFTLVP- 770
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + + +L + + N+ + ++ SF + L L L++N L + F GL +L
Sbjct: 771 -KELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRL 829
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F L++L L + N +
Sbjct: 830 LSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D++ N I R FA + L+ + N + E Q L E+ + L LQ
Sbjct: 61 DLNGNNITRITKTDFAGL-RHLRVLQLMENKISTIERG-AFQDLKELERLRLNRNHLQLF 118
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N++ + + + L +
Sbjct: 119 PELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLE 178
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 179 VLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCH 216
Score = 37.9 bits (84), Expect = 0.094
Identities = 59/266 (22%), Positives = 104/266 (39%), Gaps = 20/266 (7%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN- 141
V+++ L + + + I +F L++L VL L +NN+T + +F + L L N
Sbjct: 151 VDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNN 210
Query: 142 -----HIEQMSSETF-RHLTSLKTLI-----LANNQISTLVSRLFRMLAKLSILDLSDNP 190
H+ +S R L T L + ++ + R F S + S +
Sbjct: 211 LYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSV 270
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
L P + I CR L I T +L + E+ L +N K + F
Sbjct: 271 LHC--PAACTCSNN--IVDCRGKGLTEIPT---NLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
K+L+++ L NQ+S + + F R L+ L L N+ ++ NK
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANK 383
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNL 336
I+ + F + +L ++ N L
Sbjct: 384 INCLRVDAFQD-LHNLNLLSLYDNKL 408
Score = 37.5 bits (83), Expect = 0.12
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 155 TSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
T L T++ +N+ + L + R + +L L N T L P+ + +HL +
Sbjct: 732 TCLDTVVRCSNKGLKVLPKGIPRDVTELY---LDGNQFT-LVPKELSNYKHLTLIDLSNN 787
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
+ ++ Q + + +L L L N + + F LK L+ L L GN +SV+ + F
Sbjct: 788 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 847
Query: 274 NRELHVLTLSRN 285
L L + N
Sbjct: 848 LSALSHLAIGAN 859
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Query: 135 ELHLDHNHIEQMSSE-TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD 193
EL L++N + + F+ L L+ + +NN+I+ + F + ++ + L+ N L +
Sbjct: 537 ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLEN 596
Query: 194 LNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++FK ++ L+ R + + + + + L L +N + F +L L
Sbjct: 597 VQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 656
Query: 254 KKLKLDGN 261
L L N
Sbjct: 657 STLNLLAN 664
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L+N + + F+ L+ L LS+N+L P + K L+ L + N + +
Sbjct: 782 IDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP 841
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E L A++ + + N +CD
Sbjct: 842 EGAFNDLSALSHLAIGANPLYCD 864
Score = 32.3 bits (70), Expect = 4.7
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 359 LSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+L+ +P+N E L DL+ N ++R + + L+ L + NK+ T+ Q
Sbjct: 44 LALRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQ 100
Query: 419 RLEAIAEVNLMKNN 432
L+ + + L +N+
Sbjct: 101 DLKELERLRLNRNH 114
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NQ TLV + L+++DLS+N ++ L+ + F ++ L LR I
Sbjct: 759 LYLDGNQF-TLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + + L L L N + F L L L + N L
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 31.9 bits (69), Expect = 6.2
Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+P+ Y +HL +DLS N++S + S L L +S+N+L+ + + L+++
Sbjct: 769 VPKELSNY-KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSL 827
Query: 424 AEVNLMKNN 432
++L N+
Sbjct: 828 RLLSLHGND 836
Score = 31.5 bits (68), Expect = 8.2
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
L EIP N E + + L N + P S K L+R+D+S+N++ L+ Q L
Sbjct: 291 LTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGL 347
Query: 421 EAIAEVNLMKN 431
++ + L N
Sbjct: 348 RSLNSLVLYGN 358
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/114 (34%), Positives = 60/114 (52%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR LH+ ++ + I F GL NL L L +N LT + + F + L EL L +N++
Sbjct: 100 NLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL 159
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
E + + + SL TL L +N I + F L K++ LD++ N L L P+
Sbjct: 160 ETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPD 213
Score = 65.3 bits (152), Expect = 5e-10
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 4/183 (2%)
Query: 67 PNFLTI----GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV 122
PN T+ G +F P EL + ++ V +I + F + +L L L+ N ++ +
Sbjct: 31 PNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI 90
Query: 123 VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLS 182
F L NL LHL+ N + +++++ F L++L LIL NNQ++ + S F + L
Sbjct: 91 TPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALE 150
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
LDLS N L + + + + L ++ I + + ++ LD+ N + L
Sbjct: 151 ELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Query: 243 TSD 245
D
Sbjct: 211 PPD 213
Score = 62.1 bits (144), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%)
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
EL L N + + + F ++TSL L L+ N IS + F L L L L+ N LT +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
++F + +L L I++ + V LEELDL N + + D + L
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLH 174
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L LD N + I F ++ L ++ N+
Sbjct: 175 TLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNK 206
Score = 48.0 bits (109), Expect = 9e-05
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L +L L N ++T F L+ L+ L L+ N+L+ I ++MF LH L L+ N+
Sbjct: 77 LVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLT 136
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
D+S+N ++ +V SL T++ N
Sbjct: 137 LISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV-SLHTLSLDHN 181
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/253 (22%), Positives = 95/253 (37%), Gaps = 9/253 (3%)
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+R +L+L N ++ I F L LTLSRN ++ N+
Sbjct: 51 RRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNR 110
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
+ + F+ + +L + + N L L + + + L+ +L+ IP +
Sbjct: 111 LTKITNDMFSGL-SNLHHLILNNNQLTLISSTAFDDVFA-LEELDLSYNNLETIPWDAVE 168
Query: 371 YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL-QRLEAIAEVNLM 429
L L L N + P S + RLD++ NKLQ L L QR + +A ++
Sbjct: 169 KMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGII 228
Query: 430 KNNWHCDQCSASNMLLYMTTTVLNSTIR---VLKCHSPLRLRGATFGSLSFEQL---DPC 483
+ + + L R + C SP L G F S+ E+ P
Sbjct: 229 SPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPL 288
Query: 484 PTTHEAQMSVIAG 496
T H +M V+ G
Sbjct: 289 ITRHTHEMRVLEG 301
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/114 (34%), Positives = 60/114 (52%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR LH+ ++ + I F GL NL L L +N LT + + F + L EL L +N++
Sbjct: 100 NLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL 159
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPE 197
E + + + SL TL L +N I + F L K++ LD++ N L L P+
Sbjct: 160 ETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPD 213
Score = 65.3 bits (152), Expect = 5e-10
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 4/183 (2%)
Query: 67 PNFLTI----GPIFTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSV 122
PN T+ G +F P EL + ++ V +I + F + +L L L+ N ++ +
Sbjct: 31 PNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI 90
Query: 123 VADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLS 182
F L NL LHL+ N + +++++ F L++L LIL NNQ++ + S F + L
Sbjct: 91 TPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALE 150
Query: 183 ILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYL 242
LDLS N L + + + + L ++ I + + ++ LD+ N + L
Sbjct: 151 ELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Query: 243 TSD 245
D
Sbjct: 211 PPD 213
Score = 62.1 bits (144), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%)
Query: 135 ELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
EL L N + + + F ++TSL L L+ N IS + F L L L L+ N LT +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
++F + +L L I++ + V LEELDL N + + D + L
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLH 174
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L LD N + I F ++ L ++ N+
Sbjct: 175 TLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNK 206
Score = 48.0 bits (109), Expect = 9e-05
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L +L L N ++T F L+ L+ L L+ N+L+ I ++MF LH L L+ N+
Sbjct: 77 LVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLT 136
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGN 334
D+S+N ++ +V SL T++ N
Sbjct: 137 LISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV-SLHTLSLDHN 181
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/253 (22%), Positives = 95/253 (37%), Gaps = 9/253 (3%)
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
+R +L+L N ++ I F L LTLSRN ++ N+
Sbjct: 51 RRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNR 110
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFT 370
+ + F+ + +L + + N L L + + + L+ +L+ IP +
Sbjct: 111 LTKITNDMFSGL-SNLHHLILNNNQLTLISSTAFDDVFA-LEELDLSYNNLETIPWDAVE 168
Query: 371 YNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDL-QRLEAIAEVNLM 429
L L L N + P S + RLD++ NKLQ L L QR + +A ++
Sbjct: 169 KMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGII 228
Query: 430 KNNWHCDQCSASNMLLYMTTTVLNSTIR---VLKCHSPLRLRGATFGSLSFEQL---DPC 483
+ + + L R + C SP L G F S+ E+ P
Sbjct: 229 SPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPL 288
Query: 484 PTTHEAQMSVIAG 496
T H +M V+ G
Sbjct: 289 ITRHTHEMRVLEG 301
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/154 (25%), Positives = 71/154 (46%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL++LRVL L N ++++ F+ L L L L+ NH+
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L L L+ NQI + + FR + L L N ++ + F+ ++
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + R++ ++ +P+L L N
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 62.5 bits (145), Expect = 4e-09
Identities = 39/126 (30%), Positives = 61/126 (48%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L L +L L +N ++ + F+D++ L + R L+
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ +L LDL EN + + F +K L+LD NQ+S I D F R+L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 180 LTLNNN 185
Score = 62.5 bits (145), Expect = 4e-09
Identities = 33/103 (32%), Positives = 56/103 (54%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L LR +N ++N +T + F G + E+ L N +E + + F+ L SLKTL+L
Sbjct: 550 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 609
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N+I+ + + F L+ + +L L DN +T + P F + L
Sbjct: 610 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 652
Score = 62.1 bits (144), Expect = 5e-09
Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 26/362 (7%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + + +F GL++L L L N +T + F GL +L L L+
Sbjct: 325 SPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLN 384
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I + + F+ L +L L L +N++ T+ F L + + L+ NP + D + +
Sbjct: 385 ANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKW 444
Query: 199 FKDIQHLRIFKC--RRCLL-RRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
D H + RC RR+ N +I + + E+ L+ D F L +
Sbjct: 445 LADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPE 504
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRF 314
K + +G + N++L+ + +++N+
Sbjct: 505 KCRCEGTTVDC-------SNQKLNKIP-------------EHIPQYTAELRLNNNEFTVL 544
Query: 315 HLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEH 374
+ L+ INFS N + E + ++ + L + L+ + F E
Sbjct: 545 EATGIFKKLPQLRKINFSNNKITDIEEG-AFEGASGVNEILLTSNRLENVQHKMFKGLES 603
Query: 375 LVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWH 434
L L L N+++ ++ L + N++ T++ L +++ +NL+ N ++
Sbjct: 604 LKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFN 663
Query: 435 CD 436
C+
Sbjct: 664 CN 665
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL +L L L N I + F+ L L+ L L N
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ LF AKL LDLS+N + + + F+ ++ + + I + +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N L+ F + +L+ +L N L
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/122 (27%), Positives = 64/122 (52%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + I +F + LR ++L++N ++ + D F+GL +L L L N I
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
++ F L SL+ L+L N+I+ L F+ L L++L L DN L + F ++
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 425
Query: 205 LR 206
++
Sbjct: 426 IQ 427
Score = 55.2 bits (127), Expect = 6e-07
Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 14/284 (4%)
Query: 160 LILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
L L NN+ + L + +F+ L +L ++ S+N +TD+ F+ + L +
Sbjct: 534 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 593
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+++ + L+ L L N + +D FI L ++ L L NQ++ + F L
Sbjct: 594 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 653
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAPVVD-SLKTINFSGNN- 335
L L N ++ N + + + P+ D +++ N
Sbjct: 654 TLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGND 713
Query: 336 ----LPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
PL+ L + V +N L+ +P+ + L L N+ + P K
Sbjct: 714 DNSCSPLSRCPTECTCLDTV--VRCSNKGLKVLPKGI---PRDVTELYLDGNQFTLVP-K 767
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
LS K L +D+S+N++ TLS Q + + + L N C
Sbjct: 768 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 811
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/107 (29%), Positives = 50/107 (46%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + +++ + F G L L+L+ N + ++ FRG +++ L LD+N I
Sbjct: 105 LERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQIS 164
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+ L F + KL L N L
Sbjct: 165 CIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/133 (24%), Positives = 63/133 (47%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + + F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 304 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 363
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L LF L L +L L+ N + L + F+D+ +L + L+ I + +
Sbjct: 364 ITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPL 423
Query: 227 PRLEELDLGENLF 239
++ + L +N F
Sbjct: 424 RAIQTMHLAQNPF 436
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/129 (24%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQIS L F+ L L+ L L N +T
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
+L +F+ + L++ + + + + L L L +N + + F L+
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 425
Query: 253 LKKLKLDGN 261
++ + L N
Sbjct: 426 IQTMHLAQN 434
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
++L +++L++N ++++ +F + L L L +N + + TF L SL+ L L N
Sbjct: 773 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGND 832
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKD 201
IS + F L+ LS L + NPL D N + D
Sbjct: 833 ISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 868
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F L+ L+ L+L N++S I F +EL L L+R
Sbjct: 53 IPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNR 112
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N D+S N+I + F VD +K + N + E
Sbjct: 113 NHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVD-IKNLQLDYNQISCIEDG-A 170
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ + F + L L N L
Sbjct: 171 FRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 35/153 (22%), Positives = 60/153 (39%), Gaps = 1/153 (0%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
LDL+ N +T + F ++HLR+ + + I + + LE L L N +
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
F+ +L +L L NQ+ I F ++ L L N+
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
+++N I R + +F + L+T NNL
Sbjct: 180 LTLNNNNITRLSVASFNH-MPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/158 (26%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 319 FAPVVDSLKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
F+P L+ I+ S N + +E+A Q L ++ + L + E+P++ F L
Sbjct: 324 FSPY-KKLRRIDLSNNQI--SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 380
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQ 437
L L+ NK++ L L + NKLQT+++ L AI ++L +N + CD
Sbjct: 381 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICD- 439
Query: 438 CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
C + Y+ T + ++ +C SP RL G +
Sbjct: 440 CHLKWLADYLHTNPIETS--GARCTSPRRLANKRIGQI 475
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/124 (25%), Positives = 53/124 (42%)
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
L N I + F KL +DLS+N +++L P+ F+ ++ L + +
Sbjct: 311 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 370
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
++ + L+ L L N L D F L L L L N+L I F R + +
Sbjct: 371 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 430
Query: 282 LSRN 285
L++N
Sbjct: 431 LAQN 434
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP ECTC T V C + ++++P + RDV + + N T+ P
Sbjct: 723 CPTECTCL---------DTVVRCSNKGLKVLPKG-IPRDVTELYLDG-----NQFTLVP- 766
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + + +L + + N+ + ++ SF + L L L++N L + F GL +L
Sbjct: 767 -KELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRL 825
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F L++L L + N +
Sbjct: 826 LSLHGNDISVVPEGAFNDLSALSHLAIGANPL 857
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D++ N I R FA + L+ + N + E Q L E+ + L LQ
Sbjct: 61 DLNGNNITRITKTDFAGL-RHLRVLQLMENKISTIERG-AFQDLKELERLRLNRNHLQLF 118
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N++ + + + L +
Sbjct: 119 PELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLE 178
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 179 VLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCH 216
Score = 37.5 bits (83), Expect = 0.12
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 155 TSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
T L T++ +N+ + L + R + +L L N T L P+ + +HL +
Sbjct: 728 TCLDTVVRCSNKGLKVLPKGIPRDVTELY---LDGNQFT-LVPKELSNYKHLTLIDLSNN 783
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
+ ++ Q + + +L L L N + + F LK L+ L L GN +SV+ + F
Sbjct: 784 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 843
Query: 274 NRELHVLTLSRN 285
L L + N
Sbjct: 844 LSALSHLAIGAN 855
Score = 35.9 bits (79), Expect = 0.38
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 4/130 (3%)
Query: 207 IFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
I CR L I T +L + E+ L +N K + F K+L+++ L NQ+S +
Sbjct: 287 IVDCRGKGLTEIPT---NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISEL 343
Query: 267 VDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSL 326
+ F R L+ L L N+ ++ NKI+ + F + +L
Sbjct: 344 APDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQD-LHNL 402
Query: 327 KTINFSGNNL 336
++ N L
Sbjct: 403 NLLSLYDNKL 412
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L+N + + F+ L+ L LS+N+L P + K L+ L + N + +
Sbjct: 778 IDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP 837
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E L A++ + + N +CD
Sbjct: 838 EGAFNDLSALSHLAIGANPLYCD 860
Score = 32.3 bits (70), Expect = 4.7
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 359 LSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+L+ +P+N E L DL+ N ++R + + L+ L + NK+ T+ Q
Sbjct: 44 LALRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQ 100
Query: 419 RLEAIAEVNLMKNN 432
L+ + + L +N+
Sbjct: 101 DLKELERLRLNRNH 114
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NQ TLV + L+++DLS+N ++ L+ + F ++ L LR I
Sbjct: 755 LYLDGNQF-TLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 813
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + + L L L N + F L L L + N L
Sbjct: 814 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 857
Score = 31.9 bits (69), Expect = 6.2
Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+P+ Y +HL +DLS N++S + S L L +S+N+L+ + + L+++
Sbjct: 765 VPKELSNY-KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSL 823
Query: 424 AEVNLMKNN 432
++L N+
Sbjct: 824 RLLSLHGND 832
Score = 31.5 bits (68), Expect = 8.2
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
L EIP N E + + L N + P S K L+R+D+S+N++ L+ Q L
Sbjct: 295 LTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGL 351
Query: 421 EAIAEVNLMKN 431
++ + L N
Sbjct: 352 RSLNSLVLYGN 362
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/154 (25%), Positives = 71/154 (46%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL++LRVL L N ++++ F+ L L L L+ NH+
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L L L+ NQI + + FR + L L N ++ + F+ ++
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + R++ ++ +P+L L N
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 62.5 bits (145), Expect = 4e-09
Identities = 39/126 (30%), Positives = 61/126 (48%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L L +L L +N ++ + F+D++ L + R L+
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ +L LDL EN + + F +K L+LD NQ+S I D F R+L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 180 LTLNNN 185
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL +L L L N I + F+ L L+ L L N
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ LF AKL LDLS+N + + + F+ ++ + + I + +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N L+ F + +L+ +L N L
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 60.5 bits (140), Expect = 2e-08
Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 5/186 (2%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + + +F GL++L L L N +T + F GL +L L L+
Sbjct: 321 SPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLN 380
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I + + F+ L +L L L +N++ T+ F L + + L+ NP + D + +
Sbjct: 381 ANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKW 440
Query: 199 FKDIQHLRIFKC--RRCLL-RRI-NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
D H + RC RR+ N +I + + E+ L+ D F L +
Sbjct: 441 LADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPE 500
Query: 255 KLKLDG 260
K + +G
Sbjct: 501 KCRCEG 506
Score = 57.6 bits (133), Expect = 1e-07
Identities = 35/106 (33%), Positives = 57/106 (53%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR+++ N+ + I + +F G + + LT N L +V F+GL L L N I
Sbjct: 552 LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRIT 611
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L+S++ L L +NQI+T+ F L LS L+L NP
Sbjct: 612 CVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 657
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/122 (27%), Positives = 64/122 (52%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + I +F + LR ++L++N ++ + D F+GL +L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
++ F L SL+ L+L N+I+ L F+ L L++L L DN L + F ++
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 205 LR 206
++
Sbjct: 422 IQ 423
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/107 (29%), Positives = 50/107 (46%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + +++ + F G L L+L+ N + ++ FRG +++ L LD+N I
Sbjct: 105 LERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQIS 164
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+ L F + KL L N L
Sbjct: 165 CIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/133 (24%), Positives = 63/133 (47%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + + F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 300 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 359
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L LF L L +L L+ N + L + F+D+ +L + L+ I + +
Sbjct: 360 ITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPL 419
Query: 227 PRLEELDLGENLF 239
++ + L +N F
Sbjct: 420 RAIQTMHLAQNPF 432
Score = 54.8 bits (126), Expect = 8e-07
Identities = 60/284 (21%), Positives = 113/284 (39%), Gaps = 14/284 (4%)
Query: 160 LILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
L L NN+ + L + +F+ L +L ++ S+N +TD+ F+ + L +
Sbjct: 530 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+++ + + + L L N + +D FI L ++ L L NQ++ + F L
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLS 649
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAPVVD-SLKTINFSGNN- 335
L L N ++ N + + + P+ D +++ N
Sbjct: 650 TLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGND 709
Query: 336 ----LPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
PL+ L + V +N L+ +P+ + L L N+ + P K
Sbjct: 710 DNSCSPLSRCPTECTCLDTV--VRCSNKGLKVLPKGI---PRDVTELYLDGNQFTLVP-K 763
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
LS K L +D+S+N++ TLS Q + + + L N C
Sbjct: 764 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 807
Score = 54.0 bits (124), Expect = 1e-06
Identities = 29/103 (28%), Positives = 53/103 (51%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L LR +N ++N +T + F G + E+ L N +E + + F+ L + L+L
Sbjct: 546 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLML 605
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N+I+ + + F L+ + +L L DN +T + P F + L
Sbjct: 606 RSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSL 648
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/129 (24%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQIS L F+ L L+ L L N +T
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
+L +F+ + L++ + + + + L L L +N + + F L+
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 253 LKKLKLDGN 261
++ + L N
Sbjct: 422 IQTMHLAQN 430
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
++L +++L++N ++++ +F + L L L +N + + TF L SL+ L L N
Sbjct: 769 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGND 828
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKD 201
IS + F L+ LS L + NPL D N + D
Sbjct: 829 ISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 864
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F L+ L+ L+L N++S I F +EL L L+R
Sbjct: 53 IPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNR 112
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N D+S N+I + F VD +K + N + E
Sbjct: 113 NHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVD-IKNLQLDYNQISCIEDG-A 170
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ + F + L L N L
Sbjct: 171 FRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 35/153 (22%), Positives = 60/153 (39%), Gaps = 1/153 (0%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
LDL+ N +T + F ++HLR+ + + I + + LE L L N +
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
F+ +L +L L NQ+ I F ++ L L N+
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
+++N I R + +F + L+T NNL
Sbjct: 180 LTLNNNNITRLSVASFNH-MPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/158 (26%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 319 FAPVVDSLKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
F+P L+ I+ S N + +E+A Q L ++ + L + E+P++ F L
Sbjct: 320 FSPY-KKLRRIDLSNNQI--SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQ 437
L L+ NK++ L L + NKLQT+++ L AI ++L +N + CD
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICD- 435
Query: 438 CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
C + Y+ T + ++ +C SP RL G +
Sbjct: 436 CHLKWLADYLHTNPIETS--GARCTSPRRLANKRIGQI 471
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/124 (25%), Positives = 53/124 (42%)
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
L N I + F KL +DLS+N +++L P+ F+ ++ L + +
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
++ + L+ L L N L D F L L L L N+L I F R + +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 282 LSRN 285
L++N
Sbjct: 427 LAQN 430
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP ECTC T V C + ++++P + RDV + + N T+ P
Sbjct: 719 CPTECTCL---------DTVVRCSNKGLKVLPKG-IPRDVTELYLDG-----NQFTLVP- 762
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + + +L + + N+ + ++ SF + L L L++N L + F GL +L
Sbjct: 763 -KELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRL 821
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F L++L L + N +
Sbjct: 822 LSLHGNDISVVPEGAFNDLSALSHLAIGANPL 853
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D++ N I R FA + L+ + N + E Q L E+ + L LQ
Sbjct: 61 DLNGNNITRITKTDFAGL-RHLRVLQLMENKISTIERG-AFQDLKELERLRLNRNHLQLF 118
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N++ + + + L +
Sbjct: 119 PELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLE 178
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 179 VLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCH 216
Score = 37.9 bits (84), Expect = 0.094
Identities = 59/266 (22%), Positives = 104/266 (39%), Gaps = 20/266 (7%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN- 141
V+++ L + + + I +F L++L VL L +NN+T + +F + L L N
Sbjct: 151 VDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNN 210
Query: 142 -----HIEQMSSETF-RHLTSLKTLI-----LANNQISTLVSRLFRMLAKLSILDLSDNP 190
H+ +S R L T L + ++ + R F S + S +
Sbjct: 211 LYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSV 270
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
L P + I CR L I T +L + E+ L +N K + F
Sbjct: 271 LHC--PAACTCSNN--IVDCRGKGLTEIPT---NLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
K+L+++ L NQ+S + + F R L+ L L N+ ++ NK
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANK 383
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNL 336
I+ + F + +L ++ N L
Sbjct: 384 INCLRVDAFQD-LHNLNLLSLYDNKL 408
Score = 37.5 bits (83), Expect = 0.12
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 155 TSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
T L T++ +N+ + L + R + +L L N T L P+ + +HL +
Sbjct: 724 TCLDTVVRCSNKGLKVLPKGIPRDVTELY---LDGNQFT-LVPKELSNYKHLTLIDLSNN 779
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
+ ++ Q + + +L L L N + + F LK L+ L L GN +SV+ + F
Sbjct: 780 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 839
Query: 274 NRELHVLTLSRN 285
L L + N
Sbjct: 840 LSALSHLAIGAN 851
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L+N + + F+ L+ L LS+N+L P + K L+ L + N + +
Sbjct: 774 IDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP 833
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E L A++ + + N +CD
Sbjct: 834 EGAFNDLSALSHLAIGANPLYCD 856
Score = 32.3 bits (70), Expect = 4.7
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 359 LSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+L+ +P+N E L DL+ N ++R + + L+ L + NK+ T+ Q
Sbjct: 44 LALRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQ 100
Query: 419 RLEAIAEVNLMKNN 432
L+ + + L +N+
Sbjct: 101 DLKELERLRLNRNH 114
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NQ TLV + L+++DLS+N ++ L+ + F ++ L LR I
Sbjct: 751 LYLDGNQF-TLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 809
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + + L L L N + F L L L + N L
Sbjct: 810 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 853
Score = 31.9 bits (69), Expect = 6.2
Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+P+ Y +HL +DLS N++S + S L L +S+N+L+ + + L+++
Sbjct: 761 VPKELSNY-KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSL 819
Query: 424 AEVNLMKNN 432
++L N+
Sbjct: 820 RLLSLHGND 828
Score = 31.5 bits (68), Expect = 8.2
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
L EIP N E + + L N + P S K L+R+D+S+N++ L+ Q L
Sbjct: 291 LTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGL 347
Query: 421 EAIAEVNLMKN 431
++ + L N
Sbjct: 348 RSLNSLVLYGN 358
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 67.7 bits (158), Expect = 1e-10
Identities = 39/154 (25%), Positives = 71/154 (46%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
N L + +N+ I + F GL++LRVL L N ++++ F+ L L L L+ NH+
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
+ F L L L+ NQI + + FR + L L N ++ + F+ ++
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGEN 237
L + + R++ ++ +P+L L N
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 62.5 bits (145), Expect = 4e-09
Identities = 39/126 (30%), Positives = 61/126 (48%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N I+ + F L L +L L +N ++ + F+D++ L + R L+
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHV 279
++ +L LDL EN + + F +K L+LD NQ+S I D F R+L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 280 LTLSRN 285
LTL+ N
Sbjct: 180 LTLNNN 185
Score = 62.5 bits (145), Expect = 4e-09
Identities = 33/103 (32%), Positives = 56/103 (54%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L LR +N ++N +T + F G + E+ L N +E + + F+ L SLKTL+L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHL 205
+N+I+ + + F L+ + +L L DN +T + P F + L
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 656
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/157 (27%), Positives = 69/157 (43%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+N L+L NN+T + +F GL +L L L N I + F+ L L+ L L N
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
+ LF AKL LDLS+N + + + F+ ++ + + I + +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 227 PRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
LE L L N L+ F + +L+ +L N L
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/106 (33%), Positives = 59/106 (55%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
LR+++ N+ + I + +F G + + LT N L +V F+GL +L L L N I
Sbjct: 560 LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRIT 619
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ +++F L+S++ L L +NQI+T+ F L LS L+L NP
Sbjct: 620 CVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 665
Score = 59.7 bits (138), Expect = 3e-08
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 80 APFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLD 139
+P+ LR + + N+ + + +F GL++L L L N +T + F GL +L L L+
Sbjct: 321 SPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLN 380
Query: 140 HNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDLNPEV 198
N I + + F+ L +L L L +N++ T+ F L + + L+ NP + D + +
Sbjct: 381 ANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKW 440
Query: 199 FKDIQH 204
D H
Sbjct: 441 LADYLH 446
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/122 (27%), Positives = 64/122 (52%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
+ E+ + + + I +F + LR ++L++N ++ + D F+GL +L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQH 204
++ F L SL+ L+L N+I+ L F+ L L++L L DN L + F ++
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 205 LR 206
++
Sbjct: 422 IQ 423
Score = 55.2 bits (127), Expect = 6e-07
Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 14/284 (4%)
Query: 160 LILANNQISTL-VSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRI 218
L L NN+ + L + +F+ L +L ++ S+N +TD+ F+ + L +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 219 NTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELH 278
+++ + L+ L L N + +D FI L ++ L L NQ++ + F L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 279 VLTLSRNRXXXXXXXXXXXXXXXXXXDISHN-KIDRFHLQTFAPVVD-SLKTINFSGNN- 335
L L N ++ N + + + P+ D +++ N
Sbjct: 658 TLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGND 717
Query: 336 ----LPLNEIAIVLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFK 391
PL+ L + V +N L+ +P+ + L L N+ + P K
Sbjct: 718 DNSCSPLSRCPTECTCLDTV--VRCSNKGLKVLPKGI---PRDVTELYLDGNQFTLVP-K 771
Query: 392 LLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHC 435
LS K L +D+S+N++ TLS Q + + + L N C
Sbjct: 772 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 815
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/107 (29%), Positives = 50/107 (46%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L L + +++ + F G L L+L+ N + ++ FRG +++ L LD+N I
Sbjct: 105 LERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQIS 164
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ FR L L+ L L NN I+ L F + KL L N L
Sbjct: 165 CIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 54.8 bits (126), Expect = 8e-07
Identities = 32/133 (24%), Positives = 63/133 (47%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
+ + + L N + + F L + L +N I +++ + F+ L SL +L+L N+
Sbjct: 300 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 359
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLV 226
I+ L LF L L +L L+ N + L + F+D+ +L + L+ I + +
Sbjct: 360 ITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPL 419
Query: 227 PRLEELDLGENLF 239
++ + L +N F
Sbjct: 420 RAIQTMHLAQNPF 432
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/129 (24%), Positives = 60/129 (46%)
Query: 133 LTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLT 192
+TE+ L+ N I+ + F L+ + L+NNQIS L F+ L L+ L L N +T
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 193 DLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKR 252
+L +F+ + L++ + + + + L L L +N + + F L+
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 253 LKKLKLDGN 261
++ + L N
Sbjct: 422 IQTMHLAQN 430
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 107 QNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQ 166
++L +++L++N ++++ +F + L L L +N + + TF L SL+ L L N
Sbjct: 777 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGND 836
Query: 167 ISTLVSRLFRMLAKLSILDLSDNPL-TDLNPEVFKD 201
IS + F L+ LS L + NPL D N + D
Sbjct: 837 ISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 872
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 3/161 (1%)
Query: 226 VPR-LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSR 284
+PR E LDL N +T +F L+ L+ L+L N++S I F +EL L L+R
Sbjct: 53 IPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNR 112
Query: 285 NRXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIV 344
N D+S N+I + F VD +K + N + E
Sbjct: 113 NHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVD-IKNLQLDYNQISCIEDG-A 170
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKL 385
+ L ++ + L N ++ + F + L L N L
Sbjct: 171 FRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 35/153 (22%), Positives = 60/153 (39%), Gaps = 1/153 (0%)
Query: 184 LDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLT 243
LDL+ N +T + F ++HLR+ + + I + + LE L L N +
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 244 SDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXX 303
F+ +L +L L NQ+ I F ++ L L N+
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 304 XDISHNKIDRFHLQTFAPVVDSLKTINFSGNNL 336
+++N I R + +F + L+T NNL
Sbjct: 180 LTLNNNNITRLSVASFNH-MPKLRTFRLHSNNL 211
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/158 (26%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 319 FAPVVDSLKTINFSGNNLPLNEIAI-VLQILPEIHGVGLANLSLQEIPQNFFTYNEHLVA 377
F+P L+ I+ S N + +E+A Q L ++ + L + E+P++ F L
Sbjct: 320 FSPY-KKLRRIDLSNNQI--SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 378 LDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCDQ 437
L L+ NK++ L L + NKLQT+++ L AI ++L +N + CD
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICD- 435
Query: 438 CSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSL 475
C + Y+ T + ++ +C SP RL G +
Sbjct: 436 CHLKWLADYLHTNPIETS--GARCTSPRRLANKRIGQI 471
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/124 (25%), Positives = 53/124 (42%)
Query: 162 LANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQ 221
L N I + F KL +DLS+N +++L P+ F+ ++ L + +
Sbjct: 307 LEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKS 366
Query: 222 IYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLT 281
++ + L+ L L N L D F L L L L N+L I F R + +
Sbjct: 367 LFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH 426
Query: 282 LSRN 285
L++N
Sbjct: 427 LAQN 430
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 17/152 (11%)
Query: 16 CPDECTCTMTFDLEEGHTTQVACQHGHMRIIPVDYMDRDVHVVIIAAPPDRPNFLTIGPI 75
CP ECTC T V C + ++++P + RDV + + N T+ P
Sbjct: 727 CPTECTCL---------DTVVRCSNKGLKVLPKG-IPRDVTELYLDG-----NQFTLVP- 770
Query: 76 FTQPAPFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
+ + + +L + + N+ + ++ SF + L L L++N L + F GL +L
Sbjct: 771 -KELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRL 829
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
L L N I + F L++L L + N +
Sbjct: 830 LSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
Query: 305 DISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEI 364
D++ N I R FA + L+ + N + E Q L E+ + L LQ
Sbjct: 61 DLNGNNITRITKTDFAGL-RHLRVLQLMENKISTIERG-AFQDLKELERLRLNRNHLQLF 118
Query: 365 PQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIA 424
P+ F L LDLS N++ P K ++ L + +N++ + + + L +
Sbjct: 119 PELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLE 178
Query: 425 EVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCH 462
+ L NN ++ N + + T L+S CH
Sbjct: 179 VLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCH 216
Score = 37.9 bits (84), Expect = 0.094
Identities = 59/266 (22%), Positives = 104/266 (39%), Gaps = 20/266 (7%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHN- 141
V+++ L + + + I +F L++L VL L +NN+T + +F + L L N
Sbjct: 151 VDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNN 210
Query: 142 -----HIEQMSSETF-RHLTSLKTLI-----LANNQISTLVSRLFRMLAKLSILDLSDNP 190
H+ +S R L T L + ++ + R F S + S +
Sbjct: 211 LYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSV 270
Query: 191 LTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISL 250
L P + I CR L I T +L + E+ L +N K + F
Sbjct: 271 LHC--PAACTCSNN--IVDCRGKGLTEIPT---NLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 251 KRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDISHNK 310
K+L+++ L NQ+S + + F R L+ L L N+ ++ NK
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANK 383
Query: 311 IDRFHLQTFAPVVDSLKTINFSGNNL 336
I+ + F + +L ++ N L
Sbjct: 384 INCLRVDAFQD-LHNLNLLSLYDNKL 408
Score = 37.5 bits (83), Expect = 0.12
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 155 TSLKTLILANNQ-ISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRC 213
T L T++ +N+ + L + R + +L L N T L P+ + +HL +
Sbjct: 732 TCLDTVVRCSNKGLKVLPKGIPRDVTELY---LDGNQFT-LVPKELSNYKHLTLIDLSNN 787
Query: 214 LLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGR 273
+ ++ Q + + +L L L N + + F LK L+ L L GN +SV+ + F
Sbjct: 788 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 847
Query: 274 NRELHVLTLSRN 285
L L + N
Sbjct: 848 LSALSHLAIGAN 859
Score = 36.7 bits (81), Expect = 0.22
Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Query: 135 ELHLDHNHIEQMSSE-TFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTD 193
EL L++N + + F+ L L+ + +NN+I+ + F + ++ + L+ N L +
Sbjct: 537 ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLEN 596
Query: 194 LNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRL 253
+ ++FK ++ L+ R + + + + + L L +N + F +L L
Sbjct: 597 VQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 656
Query: 254 KKLKLDGN 261
L L N
Sbjct: 657 STLNLLAN 664
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 354 VGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLS 413
+ L+N + + F+ L+ L LS+N+L P + K L+ L + N + +
Sbjct: 782 IDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP 841
Query: 414 EQDLQRLEAIAEVNLMKNNWHCD 436
E L A++ + + N +CD
Sbjct: 842 EGAFNDLSALSHLAIGANPLYCD 864
Score = 32.3 bits (70), Expect = 4.7
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 359 LSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQ 418
L+L+ +P+N E L DL+ N ++R + + L+ L + NK+ T+ Q
Sbjct: 44 LALRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQ 100
Query: 419 RLEAIAEVNLMKNN 432
L+ + + L +N+
Sbjct: 101 DLKELERLRLNRNH 114
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L NQ TLV + L+++DLS+N ++ L+ + F ++ L LR I
Sbjct: 759 LYLDGNQF-TLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+ + + L L L N + F L L L + N L
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 31.9 bits (69), Expect = 6.2
Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 364 IPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAI 423
+P+ Y +HL +DLS N++S + S L L +S+N+L+ + + L+++
Sbjct: 769 VPKELSNY-KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSL 827
Query: 424 AEVNLMKNN 432
++L N+
Sbjct: 828 RLLSLHGND 836
Score = 31.5 bits (68), Expect = 8.2
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
L EIP N E + + L N + P S K L+R+D+S+N++ L+ Q L
Sbjct: 291 LTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGL 347
Query: 421 EAIAEVNLMKN 431
++ + L N
Sbjct: 348 RSLNSLVLYGN 358
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 67.3 bits (157), Expect = 1e-10
Identities = 45/146 (30%), Positives = 70/146 (47%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + S+ +F GL L L+L L + FRGL L L+L N ++ + +TF
Sbjct: 115 NAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTF 174
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
R L +L L L N+IS++ R FR L L L L N + ++P F+D+ L
Sbjct: 175 RDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLF 234
Query: 212 RCLLRRINTQIYHLVPRLEELDLGEN 237
L + T+ + L+ L L +N
Sbjct: 235 ANNLSALPTEALAPLRALQYLRLNDN 260
Score = 66.1 bits (154), Expect = 3e-10
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
+ L N I + + +FR +L L L +N ++ + + F LA L LDLSDN L +
Sbjct: 62 IFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSV 121
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P F + L RC L+ + ++ + L+ L L +N + L D F L L
Sbjct: 122 DPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLT 181
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN++S + + F L L L +NR
Sbjct: 182 HLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213
Score = 66.1 bits (154), Expect = 3e-10
Identities = 60/194 (30%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETF 151
S+VP+ SF +NL +L L N L + A F GL L +L L D+ + + TF
Sbjct: 70 SHVPAA---SFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L L TL L + L LFR LA L L L DN L L + F+D+ +L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + + + + L+ L L +N ++ F L RL L L N LS +
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 272 GRNRELHVLTLSRN 285
R L L L+ N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-NLTSVVADNFRGLINLTELHLDHNH 142
NL L + ++ + I +F GL L L+L+ N L SV F GL L LHLD
Sbjct: 82 NLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCG 141
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ FR L +L+ L L +N + L FR L L+ L L N ++ + F+ +
Sbjct: 142 LQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGL 201
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + + ++ + + RL L L N L ++ L+ L+ L+L+ N
Sbjct: 202 HSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/106 (33%), Positives = 53/106 (50%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L++ ++ + ++ +F L NL L L N ++SV FRGL +L L L N +
Sbjct: 156 LQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVA 215
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ FR L L TL L N +S L + L L L L+DNP
Sbjct: 216 HVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
Score = 49.2 bits (112), Expect = 4e-05
Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTLVSRLF 175
N ++ V A +FR NLT L L N + ++ + F L L+ L L++N Q+ ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 176 RMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG 235
L +L L L L +L P +F+ + L+ + L+ + + + L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 236 ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
N + F L L +L L N+++ + + F L L L N
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFAN 236
Score = 32.7 bits (71), Expect = 3.5
Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 3/123 (2%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ +P+ F L L L N+++ L L + N L L + L L
Sbjct: 190 ISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPL 249
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQL 480
A+ + L N W CD C A + ++ + + C P RL G L+ L
Sbjct: 250 RALQYLRLNDNPWVCD-CRARPLWAWLQK--FRGSSSEVPCSLPQRLAGRDLKRLAANDL 306
Query: 481 DPC 483
C
Sbjct: 307 QGC 309
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 67.3 bits (157), Expect = 1e-10
Identities = 45/146 (30%), Positives = 70/146 (47%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + S+ +F GL L L+L L + FRGL L L+L N ++ + +TF
Sbjct: 115 NAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTF 174
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
R L +L L L N+IS++ R FR L L L L N + ++P F+D+ L
Sbjct: 175 RDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLF 234
Query: 212 RCLLRRINTQIYHLVPRLEELDLGEN 237
L + T+ + L+ L L +N
Sbjct: 235 ANNLSALPTEALAPLRALQYLRLNDN 260
Score = 66.1 bits (154), Expect = 3e-10
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
+ L N I + + +FR +L L L +N ++ + + F LA L LDLSDN L +
Sbjct: 62 IFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSV 121
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P F + L RC L+ + ++ + L+ L L +N + L D F L L
Sbjct: 122 DPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLT 181
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN++S + + F L L L +NR
Sbjct: 182 HLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213
Score = 66.1 bits (154), Expect = 3e-10
Identities = 60/194 (30%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETF 151
S+VP+ SF +NL +L L N L + A F GL L +L L D+ + + TF
Sbjct: 70 SHVPAA---SFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L L TL L + L LFR LA L L L DN L L + F+D+ +L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + + + + L+ L L +N ++ F L RL L L N LS +
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 272 GRNRELHVLTLSRN 285
R L L L+ N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-NLTSVVADNFRGLINLTELHLDHNH 142
NL L + ++ + I +F GL L L+L+ N L SV F GL L LHLD
Sbjct: 82 NLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCG 141
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ FR L +L+ L L +N + L FR L L+ L L N ++ + F+ +
Sbjct: 142 LQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGL 201
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + + ++ + + RL L L N L ++ L+ L+ L+L+ N
Sbjct: 202 HSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/106 (33%), Positives = 53/106 (50%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L++ ++ + ++ +F L NL L L N ++SV FRGL +L L L N +
Sbjct: 156 LQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVA 215
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ FR L L TL L N +S L + L L L L+DNP
Sbjct: 216 HVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
Score = 49.2 bits (112), Expect = 4e-05
Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTLVSRLF 175
N ++ V A +FR NLT L L N + ++ + F L L+ L L++N Q+ ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 176 RMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG 235
L +L L L L +L P +F+ + L+ + L+ + + + L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 236 ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
N + F L L +L L N+++ + + F L L L N
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFAN 236
Score = 32.7 bits (71), Expect = 3.5
Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 3/123 (2%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ +P+ F L L L N+++ L L + N L L + L L
Sbjct: 190 ISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPL 249
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQL 480
A+ + L N W CD C A + ++ + + C P RL G L+ L
Sbjct: 250 RALQYLRLNDNPWVCD-CRARPLWAWLQK--FRGSSSEVPCSLPQRLAGRDLKRLAANDL 306
Query: 481 DPC 483
C
Sbjct: 307 QGC 309
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 67.3 bits (157), Expect = 1e-10
Identities = 45/146 (30%), Positives = 70/146 (47%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + S+ +F GL L L+L L + FRGL L L+L N ++ + +TF
Sbjct: 115 NAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTF 174
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
R L +L L L N+IS++ R FR L L L L N + ++P F+D+ L
Sbjct: 175 RDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLF 234
Query: 212 RCLLRRINTQIYHLVPRLEELDLGEN 237
L + T+ + L+ L L +N
Sbjct: 235 ANNLSALPTEALAPLRALQYLRLNDN 260
Score = 66.1 bits (154), Expect = 3e-10
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
+ L N I + + +FR +L L L +N ++ + + F LA L LDLSDN L +
Sbjct: 62 IFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSV 121
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P F + L RC L+ + ++ + L+ L L +N + L D F L L
Sbjct: 122 DPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLT 181
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN++S + + F L L L +NR
Sbjct: 182 HLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213
Score = 66.1 bits (154), Expect = 3e-10
Identities = 60/194 (30%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETF 151
S+VP+ SF +NL +L L N L + A F GL L +L L D+ + + TF
Sbjct: 70 SHVPAA---SFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L L TL L + L LFR LA L L L DN L L + F+D+ +L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + + + + L+ L L +N ++ F L RL L L N LS +
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 272 GRNRELHVLTLSRN 285
R L L L+ N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-NLTSVVADNFRGLINLTELHLDHNH 142
NL L + ++ + I +F GL L L+L+ N L SV F GL L LHLD
Sbjct: 82 NLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCG 141
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ FR L +L+ L L +N + L FR L L+ L L N ++ + F+ +
Sbjct: 142 LQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGL 201
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + + ++ + + RL L L N L ++ L+ L+ L+L+ N
Sbjct: 202 HSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/106 (33%), Positives = 53/106 (50%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L++ ++ + ++ +F L NL L L N ++SV FRGL +L L L N +
Sbjct: 156 LQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVA 215
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ FR L L TL L N +S L + L L L L+DNP
Sbjct: 216 HVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
Score = 49.2 bits (112), Expect = 4e-05
Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTLVSRLF 175
N ++ V A +FR NLT L L N + ++ + F L L+ L L++N Q+ ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 176 RMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG 235
L +L L L L +L P +F+ + L+ + L+ + + + L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 236 ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
N + F L L +L L N+++ + + F L L L N
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFAN 236
Score = 32.7 bits (71), Expect = 3.5
Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 3/123 (2%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ +P+ F L L L N+++ L L + N L L + L L
Sbjct: 190 ISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPL 249
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQL 480
A+ + L N W CD C A + ++ + + C P RL G L+ L
Sbjct: 250 RALQYLRLNDNPWVCD-CRARPLWAWLQK--FRGSSSEVPCSLPQRLAGRDLKRLAANDL 306
Query: 481 DPC 483
C
Sbjct: 307 QGC 309
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 67.3 bits (157), Expect = 1e-10
Identities = 45/146 (30%), Positives = 70/146 (47%)
Query: 92 NSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETF 151
N+ + S+ +F GL L L+L L + FRGL L L+L N ++ + +TF
Sbjct: 115 NAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTF 174
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
R L +L L L N+IS++ R FR L L L L N + ++P F+D+ L
Sbjct: 175 RDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLF 234
Query: 212 RCLLRRINTQIYHLVPRLEELDLGEN 237
L + T+ + L+ L L +N
Sbjct: 235 ANNLSALPTEALAPLRALQYLRLNDN 260
Score = 66.1 bits (154), Expect = 3e-10
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP-LTDL 194
+ L N I + + +FR +L L L +N ++ + + F LA L LDLSDN L +
Sbjct: 62 IFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSV 121
Query: 195 NPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLK 254
+P F + L RC L+ + ++ + L+ L L +N + L D F L L
Sbjct: 122 DPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLT 181
Query: 255 KLKLDGNQLSVIVDNMFGRNRELHVLTLSRNR 286
L L GN++S + + F L L L +NR
Sbjct: 182 HLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213
Score = 66.1 bits (154), Expect = 3e-10
Identities = 60/194 (30%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Query: 93 SNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHL-DHNHIEQMSSETF 151
S+VP+ SF +NL +L L N L + A F GL L +L L D+ + + TF
Sbjct: 70 SHVPAA---SFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 152 RHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCR 211
L L TL L + L LFR LA L L L DN L L + F+D+ +L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 212 RCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + + + + L+ L L +N ++ F L RL L L N LS +
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL 246
Query: 272 GRNRELHVLTLSRN 285
R L L L+ N
Sbjct: 247 APLRALQYLRLNDN 260
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHN-NLTSVVADNFRGLINLTELHLDHNH 142
NL L + ++ + I +F GL L L+L+ N L SV F GL L LHLD
Sbjct: 82 NLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCG 141
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
++++ FR L +L+ L L +N + L FR L L+ L L N ++ + F+ +
Sbjct: 142 LQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGL 201
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGN 261
L + + ++ + + RL L L N L ++ L+ L+ L+L+ N
Sbjct: 202 HSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/106 (33%), Positives = 53/106 (50%)
Query: 85 LRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIE 144
L+ L++ ++ + ++ +F L NL L L N ++SV FRGL +L L L N +
Sbjct: 156 LQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVA 215
Query: 145 QMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ FR L L TL L N +S L + L L L L+DNP
Sbjct: 216 HVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
Score = 49.2 bits (112), Expect = 4e-05
Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Query: 117 NNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANN-QISTLVSRLF 175
N ++ V A +FR NLT L L N + ++ + F L L+ L L++N Q+ ++ F
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 176 RMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLG 235
L +L L L L +L P +F+ + L+ + L+ + + + L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 236 ENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
N + F L L +L L N+++ + + F L L L N
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFAN 236
Score = 32.7 bits (71), Expect = 3.5
Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 3/123 (2%)
Query: 361 LQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRL 420
+ +P+ F L L L N+++ L L + N L L + L L
Sbjct: 190 ISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPL 249
Query: 421 EAIAEVNLMKNNWHCDQCSASNMLLYMTTTVLNSTIRVLKCHSPLRLRGATFGSLSFEQL 480
A+ + L N W CD C A + ++ + + C P RL G L+ L
Sbjct: 250 RALQYLRLNDNPWVCD-CRARPLWAWLQK--FRGSSSEVPCSLPQRLAGRDLKRLAANDL 306
Query: 481 DPC 483
C
Sbjct: 307 QGC 309
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 8/161 (4%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ + + + SF GL L++L+L+ N + S+ + F+ L NL+ L L N + +++
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP-----EVFKDI 202
+ETFR L L+ L L N+I + F L +L L L DN L L P + D+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVP-RLEELDLGENLFKYL 242
H + +L N + L L++LD E LF L
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLGLQQLD--EGLFSRL 215
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 10/205 (4%)
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+P L+ LDL +N L S F L L L L N+L I + F R L L L +N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV-VDSLKTINFSGNNLPLNEIAIV 344
R + N+ L+ P+ + L ++ S N+L E I+
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNE-----LRALPPLRLPRLLLLDLSHNSLLALEPGIL 189
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
+ + LA L LQ++ + F+ +L LD+S N+L R P ++ + L RL +
Sbjct: 190 --DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-PVIRGLRGLTRLRL 246
Query: 405 SHN-KLQTLSEQDLQRLEAIAEVNL 428
+ N ++ L +DL L A+ E+++
Sbjct: 247 AGNTRIAQLRPEDLAGLAALQELDV 271
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/107 (31%), Positives = 53/107 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L + N I+ L + F L L +LDLS N + L VF+ + +L L I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
+ + + RLE L LG+N +++ F +L RL +LKL N+L +
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL 163
Score = 41.5 bits (93), Expect = 0.008
Identities = 61/301 (20%), Positives = 122/301 (40%), Gaps = 11/301 (3%)
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF 247
+N +T L+ F + L++ + + + + ++ + L LDL N +T++ F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDIS 307
L+RL++L L N++ I F L L L N D+S
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE---LRALPPLRLPRLLLLDLS 177
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
HN + L+ +++ + +G L + + + L +H + +++ L+ +P
Sbjct: 178 HNSL--LALEPGILDTANVEALRLAGLGLQQLDEGLFSR-LRNLHDLDVSDNQLERVPP- 233
Query: 368 FFTYNEHLVALDLSWN-KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
L L L+ N ++++ + L+ LQ LD+S+ LQ L + +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Query: 427 NLMKNNWHCDQCSASNMLLYMTTT-VLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPT 485
+N ++C C S ++ + V ++ +CH P + G L + CP
Sbjct: 294 AAARNPFNC-VCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFG-CPA 351
Query: 486 T 486
T
Sbjct: 352 T 352
Score = 34.7 bits (76), Expect = 0.88
Identities = 55/226 (24%), Positives = 86/226 (38%), Gaps = 24/226 (10%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NL L + + + I +F GL+ L L L N + + F L L EL L
Sbjct: 98 PLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQD 157
Query: 141 NHIEQMSSETFRHL--------------------TSLKTLILANNQISTLVSRLFRMLAK 180
N + + L +++ L LA + L LF L
Sbjct: 158 NELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRN 217
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHL-RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
L LD+SDN L + P V + ++ L R+ + ++ + + L+ELD+
Sbjct: 218 LHDLDVSDNQLERV-PPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSL 276
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVD-NMFGR-NRELHVLTLS 283
+ L D RL+ L N + + + FG RE HV S
Sbjct: 277 QALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLAS 322
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 8/161 (4%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ + + + SF GL L++L+L+ N + S+ + F+ L NL+ L L N + +++
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP-----EVFKDI 202
+ETFR L L+ L L N+I + F L +L L L DN L L P + D+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVP-RLEELDLGENLFKYL 242
H + +L N + L L++LD E LF L
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLGLQQLD--EGLFSRL 215
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 10/205 (4%)
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+P L+ LDL +N L S F L L L L N+L I + F R L L L +N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV-VDSLKTINFSGNNLPLNEIAIV 344
R + N+ L+ P+ + L ++ S N+L E I+
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNE-----LRALPPLRLPRLLLLDLSHNSLLALEPGIL 189
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
+ + LA L LQ++ + F+ +L LD+S N+L R P ++ + L RL +
Sbjct: 190 --DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-PVIRGLRGLTRLRL 246
Query: 405 SHN-KLQTLSEQDLQRLEAIAEVNL 428
+ N ++ L +DL L A+ E+++
Sbjct: 247 AGNTRIAQLRPEDLAGLAALQELDV 271
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/107 (31%), Positives = 53/107 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L + N I+ L + F L L +LDLS N + L VF+ + +L L I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
+ + + RLE L LG+N +++ F +L RL +LKL N+L +
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL 163
Score = 41.5 bits (93), Expect = 0.008
Identities = 61/301 (20%), Positives = 122/301 (40%), Gaps = 11/301 (3%)
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF 247
+N +T L+ F + L++ + + + + ++ + L LDL N +T++ F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDIS 307
L+RL++L L N++ I F L L L N D+S
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE---LRALPPLRLPRLLLLDLS 177
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
HN + L+ +++ + +G L + + + L +H + +++ L+ +P
Sbjct: 178 HNSL--LALEPGILDTANVEALRLAGLGLQQLDEGLFSR-LRNLHDLDVSDNQLERVPP- 233
Query: 368 FFTYNEHLVALDLSWN-KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
L L L+ N ++++ + L+ LQ LD+S+ LQ L + +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Query: 427 NLMKNNWHCDQCSASNMLLYMTTT-VLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPT 485
+N ++C C S ++ + V ++ +CH P + G L + CP
Sbjct: 294 AAARNPFNC-VCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFG-CPA 351
Query: 486 T 486
T
Sbjct: 352 T 352
Score = 34.7 bits (76), Expect = 0.88
Identities = 55/226 (24%), Positives = 86/226 (38%), Gaps = 24/226 (10%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NL L + + + I +F GL+ L L L N + + F L L EL L
Sbjct: 98 PLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQD 157
Query: 141 NHIEQMSSETFRHL--------------------TSLKTLILANNQISTLVSRLFRMLAK 180
N + + L +++ L LA + L LF L
Sbjct: 158 NELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRN 217
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHL-RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
L LD+SDN L + P V + ++ L R+ + ++ + + L+ELD+
Sbjct: 218 LHDLDVSDNQLERV-PPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSL 276
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVD-NMFGR-NRELHVLTLS 283
+ L D RL+ L N + + + FG RE HV S
Sbjct: 277 QALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLAS 322
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 8/161 (4%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
L++ + + + SF GL L++L+L+ N + S+ + F+ L NL+ L L N + +++
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNP-----EVFKDI 202
+ETFR L L+ L L N+I + F L +L L L DN L L P + D+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDL 176
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVP-RLEELDLGENLFKYL 242
H + +L N + L L++LD E LF L
Sbjct: 177 SHNSLLALEPGILDTANVEALRLAGLGLQQLD--EGLFSRL 215
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 10/205 (4%)
Query: 226 VPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
+P L+ LDL +N L S F L L L L N+L I + F R L L L +N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 286 RXXXXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPV-VDSLKTINFSGNNLPLNEIAIV 344
R + N+ L+ P+ + L ++ S N+L E I+
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNE-----LRALPPLRLPRLLLLDLSHNSLLALEPGIL 189
Query: 345 LQILPEIHGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLDI 404
+ + LA L LQ++ + F+ +L LD+S N+L R P ++ + L RL +
Sbjct: 190 --DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-PVIRGLRGLTRLRL 246
Query: 405 SHN-KLQTLSEQDLQRLEAIAEVNL 428
+ N ++ L +DL L A+ E+++
Sbjct: 247 AGNTRIAQLRPEDLAGLAALQELDV 271
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/107 (31%), Positives = 53/107 (49%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L + N I+ L + F L L +LDLS N + L VF+ + +L L I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVI 266
+ + + RLE L LG+N +++ F +L RL +LKL N+L +
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL 163
Score = 41.5 bits (93), Expect = 0.008
Identities = 61/301 (20%), Positives = 122/301 (40%), Gaps = 11/301 (3%)
Query: 188 DNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEF 247
+N +T L+ F + L++ + + + + ++ + L LDL N +T++ F
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 248 ISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXXXXXXXXXXXXXXXXXXDIS 307
L+RL++L L N++ I F L L L N D+S
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE---LRALPPLRLPRLLLLDLS 177
Query: 308 HNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEIHGVGLANLSLQEIPQN 367
HN + L+ +++ + +G L + + + L +H + +++ L+ +P
Sbjct: 178 HNSL--LALEPGILDTANVEALRLAGLGLQQLDEGLFSR-LRNLHDLDVSDNQLERVPP- 233
Query: 368 FFTYNEHLVALDLSWN-KLSRFPFKLLSKTKFLQRLDISHNKLQTLSEQDLQRLEAIAEV 426
L L L+ N ++++ + L+ LQ LD+S+ LQ L + +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Query: 427 NLMKNNWHCDQCSASNMLLYMTTT-VLNSTIRVLKCHSPLRLRGATFGSLSFEQLDPCPT 485
+N ++C C S ++ + V ++ +CH P + G L + CP
Sbjct: 294 AAARNPFNC-VCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFG-CPA 351
Query: 486 T 486
T
Sbjct: 352 T 352
Score = 34.7 bits (76), Expect = 0.88
Identities = 55/226 (24%), Positives = 86/226 (38%), Gaps = 24/226 (10%)
Query: 81 PFVNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDH 140
P NL L + + + I +F GL+ L L L N + + F L L EL L
Sbjct: 98 PLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQD 157
Query: 141 NHIEQMSSETFRHL--------------------TSLKTLILANNQISTLVSRLFRMLAK 180
N + + L +++ L LA + L LF L
Sbjct: 158 NELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRN 217
Query: 181 LSILDLSDNPLTDLNPEVFKDIQHL-RIFKCRRCLLRRINTQIYHLVPRLEELDLGENLF 239
L LD+SDN L + P V + ++ L R+ + ++ + + L+ELD+
Sbjct: 218 LHDLDVSDNQLERV-PPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSL 276
Query: 240 KYLTSDEFISLKRLKKLKLDGNQLSVIVD-NMFGR-NRELHVLTLS 283
+ L D RL+ L N + + + FG RE HV S
Sbjct: 277 QALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLAS 322
>BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRP--NFLTIGPIFTQ--PAPFVNLRE---LHIVNSNVPS 97
I+ V +R + + +PP P + L G + + P FVN LH+ ++ +
Sbjct: 60 ILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQD 119
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F GL+ LR L+L +N L + D F GL NL L +D+N+I + F L L
Sbjct: 120 IETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLL 179
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ LIL +N +S+L + LFR + L+ LDL N L
Sbjct: 180 QVLILNDNLLSSLPNNLFRFV-PLTHLDLRGNRL 212
Score = 63.3 bits (147), Expect = 2e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N +++L N+I + F T L L L NN+IS + R F L L L L+ N +
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L+PE+F +Q L+ + L+R I + + VP L+ L L NL + + S F L
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGL- 528
Query: 252 RLKKLKLDGNQL-SVIVDNMFGRNRELHVLTLSRN 285
L +L L N S+ V + + + L + L N
Sbjct: 529 TLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F+GLQ+L+ L L +N + + + F + NL L L++N +
Sbjct: 458 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLL 517
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ M S F LT L+ + +N+ S VS + L L +DL DNP
Sbjct: 518 QAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNP 564
Score = 58.4 bits (135), Expect = 6e-08
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + F GL L LHL++N +E + +TF L +L+ L + N IS +
Sbjct: 109 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 168
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFK--DIQHLRIFKCRRCLLRRINTQIYHLVPR 228
F L L +L L+DN L+ L +F+ + HL + R LL + + H+ +
Sbjct: 169 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGL-LQHM-DK 226
Query: 229 LEELDLGENLFKYLTSDEFISLK 251
+ EL L EN + S E ISLK
Sbjct: 227 VVELQLEEN--PWNCSCELISLK 247
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
LH+ N+ + I +F L NLR L L N + + + F GL +L L L +N I ++
Sbjct: 438 LHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQ 497
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
S TF + +L+ L L NN + + S +F L L L+L N T L
Sbjct: 498 SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSL 543
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
LS N L L P F + I +++ I T +H + L L L N + L D
Sbjct: 88 LSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDD 147
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F+ L+ L+ L++D N +SVI N FG+ L VL L+ N
Sbjct: 148 TFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + + LT N + V +F L LHL +N I + F LT+L+ L L N+I
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L LF L L L L N + ++ F + +L++ LL+ + + ++ +
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLT 529
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F L S LK L ++ L N
Sbjct: 530 LL-RLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L+ N L + + F + LHL N I+ + + F L L+ L L NN++ L
Sbjct: 86 LLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLR 145
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L + N ++ + P F + L++ LL + ++ VP L
Sbjct: 146 DDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVP-LTH 204
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGN 261
LDL N K L + + ++ +L+L+ N
Sbjct: 205 LDLRGNRLKLLPYVGLLQHMDKVVELQLEEN 235
>BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRP--NFLTIGPIFTQ--PAPFVNLRE---LHIVNSNVPS 97
I+ V +R + + +PP P + L G + + P FVN LH+ ++ +
Sbjct: 60 ILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQD 119
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F GL+ LR L+L +N L + D F GL NL L +D+N+I + F L L
Sbjct: 120 IETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLL 179
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ LIL +N +S+L + LFR + L+ LDL N L
Sbjct: 180 QVLILNDNLLSSLPNNLFRFV-PLTHLDLRGNRL 212
Score = 63.3 bits (147), Expect = 2e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N +++L N+I + F T L L L NN+IS + R F L L L L+ N +
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L+PE+F +Q L+ + L+R I + + VP L+ L L NL + + S F L
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGL- 528
Query: 252 RLKKLKLDGNQL-SVIVDNMFGRNRELHVLTLSRN 285
L +L L N S+ V + + + L + L N
Sbjct: 529 TLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F+GLQ+L+ L L +N + + + F + NL L L++N +
Sbjct: 458 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLL 517
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ M S F LT L+ + +N+ S VS + L L +DL DNP
Sbjct: 518 QAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNP 564
Score = 58.4 bits (135), Expect = 6e-08
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + F GL L LHL++N +E + +TF L +L+ L + N IS +
Sbjct: 109 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 168
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFK--DIQHLRIFKCRRCLLRRINTQIYHLVPR 228
F L L +L L+DN L+ L +F+ + HL + R LL + + H+ +
Sbjct: 169 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGL-LQHM-DK 226
Query: 229 LEELDLGENLFKYLTSDEFISLK 251
+ EL L EN + S E ISLK
Sbjct: 227 VVELQLEEN--PWNCSCELISLK 247
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
LH+ N+ + I +F L NLR L L N + + + F GL +L L L +N I ++
Sbjct: 438 LHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQ 497
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
S TF + +L+ L L NN + + S +F L L L+L N T L
Sbjct: 498 SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSL 543
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
LS N L L P F + I +++ I T +H + L L L N + L D
Sbjct: 88 LSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDD 147
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F+ L+ L+ L++D N +SVI N FG+ L VL L+ N
Sbjct: 148 TFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + + LT N + V +F L LHL +N I + F LT+L+ L L N+I
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L LF L L L L N + ++ F + +L++ LL+ + + ++ +
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLT 529
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F L S LK L ++ L N
Sbjct: 530 LL-RLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L+ N L + + F + LHL N I+ + + F L L+ L L NN++ L
Sbjct: 86 LLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLR 145
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L + N ++ + P F + L++ LL + ++ VP L
Sbjct: 146 DDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVP-LTH 204
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGN 261
LDL N K L + + ++ +L+L+ N
Sbjct: 205 LDLRGNRLKLLPYVGLLQHMDKVVELQLEEN 235
>BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRP--NFLTIGPIFTQ--PAPFVNLRE---LHIVNSNVPS 97
I+ V +R + + +PP P + L G + + P FVN LH+ ++ +
Sbjct: 60 ILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQD 119
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F GL+ LR L+L +N L + D F GL NL L +D+N+I + F L L
Sbjct: 120 IETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLL 179
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ LIL +N +S+L + LFR + L+ LDL N L
Sbjct: 180 QVLILNDNLLSSLPNNLFRFV-PLTHLDLRGNRL 212
Score = 63.3 bits (147), Expect = 2e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N +++L N+I + F T L L L NN+IS + R F L L L L+ N +
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L+PE+F +Q L+ + L+R I + + VP L+ L L NL + + S F L
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGL- 528
Query: 252 RLKKLKLDGNQL-SVIVDNMFGRNRELHVLTLSRN 285
L +L L N S+ V + + + L + L N
Sbjct: 529 TLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F+GLQ+L+ L L +N + + + F + NL L L++N +
Sbjct: 458 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLL 517
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ M S F LT L+ + +N+ S VS + L L +DL DNP
Sbjct: 518 QAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNP 564
Score = 58.4 bits (135), Expect = 6e-08
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + F GL L LHL++N +E + +TF L +L+ L + N IS +
Sbjct: 109 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 168
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFK--DIQHLRIFKCRRCLLRRINTQIYHLVPR 228
F L L +L L+DN L+ L +F+ + HL + R LL + + H+ +
Sbjct: 169 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGL-LQHM-DK 226
Query: 229 LEELDLGENLFKYLTSDEFISLK 251
+ EL L EN + S E ISLK
Sbjct: 227 VVELQLEEN--PWNCSCELISLK 247
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
LH+ N+ + I +F L NLR L L N + + + F GL +L L L +N I ++
Sbjct: 438 LHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQ 497
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
S TF + +L+ L L NN + + S +F L L L+L N T L
Sbjct: 498 SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSL 543
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
LS N L L P F + I +++ I T +H + L L L N + L D
Sbjct: 88 LSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDD 147
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F+ L+ L+ L++D N +SVI N FG+ L VL L+ N
Sbjct: 148 TFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + + LT N + V +F L LHL +N I + F LT+L+ L L N+I
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L LF L L L L N + ++ F + +L++ LL+ + + ++ +
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLT 529
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F L S LK L ++ L N
Sbjct: 530 LL-RLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L+ N L + + F + LHL N I+ + + F L L+ L L NN++ L
Sbjct: 86 LLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLR 145
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L + N ++ + P F + L++ LL + ++ VP L
Sbjct: 146 DDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVP-LTH 204
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGN 261
LDL N K L + + ++ +L+L+ N
Sbjct: 205 LDLRGNRLKLLPYVGLLQHMDKVVELQLEEN 235
>AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRP--NFLTIGPIFTQ--PAPFVNLRE---LHIVNSNVPS 97
I+ V +R + + +PP P + L G + + P FVN LH+ ++ +
Sbjct: 60 ILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQD 119
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F GL+ LR L+L +N L + D F GL NL L +D+N+I + F L L
Sbjct: 120 IETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLL 179
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ LIL +N +S+L + LFR + L+ LDL N L
Sbjct: 180 QVLILNDNLLSSLPNNLFRFV-PLTHLDLRGNRL 212
Score = 63.3 bits (147), Expect = 2e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N +++L N+I + F T L L L NN+IS + R F L L L L+ N +
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L+PE+F +Q L+ + L+R I + + VP L+ L L NL + + S F L
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGL- 528
Query: 252 RLKKLKLDGNQL-SVIVDNMFGRNRELHVLTLSRN 285
L +L L N S+ V + + + L + L N
Sbjct: 529 TLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F+GLQ+L+ L L +N + + + F + NL L L++N +
Sbjct: 458 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLL 517
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ M S F LT L+ + +N+ S VS + L L +DL DNP
Sbjct: 518 QAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNP 564
Score = 58.4 bits (135), Expect = 6e-08
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + F GL L LHL++N +E + +TF L +L+ L + N IS +
Sbjct: 109 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 168
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFK--DIQHLRIFKCRRCLLRRINTQIYHLVPR 228
F L L +L L+DN L+ L +F+ + HL + R LL + + H+ +
Sbjct: 169 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGL-LQHM-DK 226
Query: 229 LEELDLGENLFKYLTSDEFISLK 251
+ EL L EN + S E ISLK
Sbjct: 227 VVELQLEEN--PWNCSCELISLK 247
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
LH+ N+ + I +F L NLR L L N + + + F GL +L L L +N I ++
Sbjct: 438 LHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQ 497
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
S TF + +L+ L L NN + + S +F L L L+L N T L
Sbjct: 498 SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSL 543
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
LS N L L P F + I +++ I T +H + L L L N + L D
Sbjct: 88 LSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDD 147
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F+ L+ L+ L++D N +SVI N FG+ L VL L+ N
Sbjct: 148 TFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + + LT N + V +F L LHL +N I + F LT+L+ L L N+I
Sbjct: 410 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 469
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L LF L L L L N + ++ F + +L++ LL+ + + ++ +
Sbjct: 470 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLT 529
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F L S LK L ++ L N
Sbjct: 530 LL-RLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 563
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L+ N L + + F + LHL N I+ + + F L L+ L L NN++ L
Sbjct: 86 LLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLR 145
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L + N ++ + P F + L++ LL + ++ VP L
Sbjct: 146 DDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVP-LTH 204
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGN 261
LDL N K L + + ++ +L+L+ N
Sbjct: 205 LDLRGNRLKLLPYVGLLQHMDKVVELQLEEN 235
>AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens
cDNA FLJ23995 fis, clone HRC11525. ).
Length = 459
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/182 (24%), Positives = 91/182 (50%)
Query: 83 VNLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNH 142
++L +L + N+ ++ + L++L L+L H N+ ++ F+ L +L L +D+
Sbjct: 30 LSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWP 89
Query: 143 IEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDI 202
+ M + +L +L + N +ST+ F+ L L+ L+LS NP++ + +F D+
Sbjct: 90 LLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDL 149
Query: 203 QHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQ 262
L+ LR I + + L L++ +NL + L + F S + L+ L ++ N
Sbjct: 150 IRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNP 209
Query: 263 LS 264
L+
Sbjct: 210 LA 211
Score = 65.3 bits (152), Expect = 5e-10
Identities = 51/202 (25%), Positives = 93/202 (46%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NL+ L + ++++ I +F GL +L L L NLT+V + L +L LHL H +I
Sbjct: 7 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 66
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQ 203
M F+ L LK L + + ++ L+ L +++ L+ + FK +
Sbjct: 67 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLV 126
Query: 204 HLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQL 263
+L + I ++ + RL+EL + + + F L+ L+ L + N L
Sbjct: 127 YLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLL 186
Query: 264 SVIVDNMFGRNRELHVLTLSRN 285
+ +N+F R L VL+++ N
Sbjct: 187 ETLEENVFSSPRALEVLSINNN 208
Score = 63.3 bits (147), Expect = 2e-09
Identities = 51/183 (27%), Positives = 84/183 (45%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F L NL+ L + N+L + F GL++L +L L+ ++ + +E HL SL +L L
Sbjct: 2 FQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHL 61
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQI 222
+ I+ + F+ L L L++ PL D+ P +L L +
Sbjct: 62 KHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLA 121
Query: 223 YHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTL 282
+ + L L+L N + + F L RL++L + G QL I + F R L VL +
Sbjct: 122 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 181
Query: 283 SRN 285
S+N
Sbjct: 182 SQN 184
Score = 35.5 bits (78), Expect = 0.50
Identities = 48/213 (22%), Positives = 83/213 (38%), Gaps = 12/213 (5%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRNRXX 288
L+ L++G+N Y++ F L L++L L+ L+ + R L L L
Sbjct: 8 LKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKH---- 63
Query: 289 XXXXXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQIL 348
+ H +ID + L P +SL +N + ++ ++ V L
Sbjct: 64 -LNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPA-NSLYGLNLTSLSVTNTNLSTV-PFL 120
Query: 349 PEIHGVGLANLSLQEIP-----QNFFTYNEHLVALDLSWNKLSRFPFKLLSKTKFLQRLD 403
H V L +L+L P F+ L L + +L +FL+ L+
Sbjct: 121 AFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLN 180
Query: 404 ISHNKLQTLSEQDLQRLEAIAEVNLMKNNWHCD 436
+S N L+TL E A+ +++ N CD
Sbjct: 181 VSQNLLETLEENVFSSPRALEVLSINNNPLACD 213
Score = 31.5 bits (68), Expect = 8.2
Identities = 43/215 (20%), Positives = 85/215 (39%), Gaps = 6/215 (2%)
Query: 174 LFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELD 233
+F+ L L L++ DN L ++ F + L +C L + T+ + L L
Sbjct: 1 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 60
Query: 234 LGENLFKYLTSDEFISLKRLKKLKLDGNQL--SVIVDNMFGRNRELHVLTLSRNRXXXXX 291
L + F L LK L++D L + ++++G N L L+++
Sbjct: 61 LKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN--LTSLSVTNTNLSTVP 118
Query: 292 XXXXXXXXXXXXXDISHNKIDRFHLQTFAPVVDSLKTINFSGNNLPLNEIAIVLQILPEI 351
++S+N I F+ ++ L+ ++ G L E Q L +
Sbjct: 119 FLAFKHLVYLTHLNLSYNPISTIEAGMFSDLI-RLQELHIVGAQLRTIE-PHSFQGLRFL 176
Query: 352 HGVGLANLSLQEIPQNFFTYNEHLVALDLSWNKLS 386
+ ++ L+ + +N F+ L L ++ N L+
Sbjct: 177 RVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 211
>AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein.
Length = 966
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 45 IIPVDYMDRDVHVVIIAAPPDRP--NFLTIGPIFTQ--PAPFVNLRE---LHIVNSNVPS 97
I+ V +R + + +PP P + L G + + P FVN LH+ ++ +
Sbjct: 68 ILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQD 127
Query: 98 IGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSL 157
I +F GL+ LR L+L +N L + D F GL NL L +D+N+I + F L L
Sbjct: 128 IETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLL 187
Query: 158 KTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
+ LIL +N +S+L + LFR + L+ LDL N L
Sbjct: 188 QVLILNDNLLSSLPNNLFRFV-PLTHLDLRGNRL 220
Score = 63.3 bits (147), Expect = 2e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Query: 132 NLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
N +++L N+I + F T L L L NN+IS + R F L L L L+ N +
Sbjct: 418 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 477
Query: 192 TDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSDEFISLK 251
L+PE+F +Q L+ + L+R I + + VP L+ L L NL + + S F L
Sbjct: 478 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGL- 536
Query: 252 RLKKLKLDGNQL-SVIVDNMFGRNRELHVLTLSRN 285
L +L L N S+ V + + + L + L N
Sbjct: 537 TLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 571
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
NLR L++ + + + F+GLQ+L+ L L +N + + + F + NL L L++N +
Sbjct: 466 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLL 525
Query: 144 EQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNP 190
+ M S F LT L+ + +N+ S VS + L L +DL DNP
Sbjct: 526 QAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNP 572
Score = 58.4 bits (135), Expect = 6e-08
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 111 VLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTL 170
+L+L N + + F GL L LHL++N +E + +TF L +L+ L + N IS +
Sbjct: 117 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVI 176
Query: 171 VSRLFRMLAKLSILDLSDNPLTDLNPEVFK--DIQHLRIFKCRRCLLRRINTQIYHLVPR 228
F L L +L L+DN L+ L +F+ + HL + R LL + + H+ +
Sbjct: 177 EPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGL-LQHM-DK 234
Query: 229 LEELDLGENLFKYLTSDEFISLK 251
+ EL L EN + S E ISLK
Sbjct: 235 VVELQLEEN--PWNCSCELISLK 255
Score = 55.6 bits (128), Expect = 4e-07
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 88 LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMS 147
LH+ N+ + I +F L NLR L L N + + + F GL +L L L +N I ++
Sbjct: 446 LHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQ 505
Query: 148 SETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPLTDL 194
S TF + +L+ L L NN + + S +F L L L+L N T L
Sbjct: 506 SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSL 551
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 186 LSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEELDLGENLFKYLTSD 245
LS N L L P F + I +++ I T +H + L L L N + L D
Sbjct: 96 LSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDD 155
Query: 246 EFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
F+ L+ L+ L++D N +SVI N FG+ L VL L+ N
Sbjct: 156 TFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 195
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%)
Query: 108 NLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQI 167
N + + LT N + V +F L LHL +N I + F LT+L+ L L N+I
Sbjct: 418 NPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRI 477
Query: 168 STLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVP 227
L LF L L L L N + ++ F + +L++ LL+ + + ++ +
Sbjct: 478 ERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLT 537
Query: 228 RLEELDLGENLFKYL-TSDEFISLKRLKKLKLDGN 261
L L+L N F L S LK L ++ L N
Sbjct: 538 LL-RLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDN 571
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L+ N L + + F + LHL N I+ + + F L L+ L L NN++ L
Sbjct: 94 LLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLR 153
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L + N ++ + P F + L++ LL + ++ VP L
Sbjct: 154 DDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVP-LTH 212
Query: 232 LDLGENLFKYLTSDEFIS-LKRLKKLKLDGN 261
LDL N K L + + ++ +L+L+ N
Sbjct: 213 LDLRGNRLKLLPYVGLLQHMDKVVELQLEEN 243
>Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein.
Length = 845
Score = 66.1 bits (154), Expect = 3e-10
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Query: 79 PAPFVNLRE---LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
P FVN LH+ N+ + I +F GL+ L+ L+L +N L + D F GL +L
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEY 138
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
L D+N+I + + F L LK LIL +N + +L S +FR + L+ LDL N L
Sbjct: 139 LQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRL 193
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/98 (36%), Positives = 50/98 (51%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F N L+L +N L + F GL L LHL++N +E + +TF L SL+ L
Sbjct: 82 FVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQA 141
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N IS + + F L KL +L L+DN L L VF+
Sbjct: 142 DYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR 179
Score = 54.8 bits (126), Expect = 8e-07
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L LT N L +V ++ +L LHL +N I + F +LTSL+ L L N + L
Sbjct: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+F L L L L N + ++ P F + +L++ LLR + I+ L
Sbjct: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG-GTALTR 498
Query: 232 LDLGENLFKYL 242
L+L N F +L
Sbjct: 499 LNLRNNHFSHL 509
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N LT + + F N LHL +N ++++ + F L +LK L L NN++ L
Sbjct: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L N ++ + F + L++ LL + + ++ V L
Sbjct: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLTH 185
Query: 232 LDLGENLFKYL 242
LDL N K +
Sbjct: 186 LDLRGNRLKVM 196
Score = 45.6 bits (103), Expect = 5e-04
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L++ + + + F GLQ+L+ L L +N + + F LINL L L++N +
Sbjct: 424 SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ F T+L L L NN S L V + L +DL +NP
Sbjct: 484 RSLPDNIFGG-TALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 35.9 bits (79), Expect = 0.38
Identities = 20/57 (35%), Positives = 29/57 (50%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L LG N + F +L L++L L+GN L V+ +MF + L L L N
Sbjct: 401 LDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457
Score = 32.7 bits (71), Expect = 3.5
Identities = 26/112 (23%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N ++ L F + L L +N L ++ F ++ L+ L +
Sbjct: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + LE L N + + F L +LK L L+ N L + N+F
Sbjct: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVF 178
>BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 66.1 bits (154), Expect = 3e-10
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
Query: 79 PAPFVNLRE---LHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTE 135
P FVN LH+ N+ + I +F GL+ L+ L+L +N L + D F GL +L
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEY 138
Query: 136 LHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLVSRLFRMLAKLSILDLSDNPL 191
L D+N+I + + F L LK LIL +N + +L S +FR + L+ LDL N L
Sbjct: 139 LQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRL 193
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/98 (36%), Positives = 50/98 (51%)
Query: 103 FWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLIL 162
F N L+L +N L + F GL L LHL++N +E + +TF L SL+ L
Sbjct: 82 FVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQA 141
Query: 163 ANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFK 200
N IS + + F L KL +L L+DN L L VF+
Sbjct: 142 DYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR 179
Score = 54.8 bits (126), Expect = 8e-07
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L LT N L +V ++ +L LHL +N I + F +LTSL+ L L N + L
Sbjct: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
+F L L L L N + ++ P F + +L++ LLR + I+ L
Sbjct: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG-GTALTR 498
Query: 232 LDLGENLFKYL 242
L+L N F +L
Sbjct: 499 LNLRNNHFSHL 509
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
Query: 112 LNLTHNNLTSVVADNFRGLINLTELHLDHNHIEQMSSETFRHLTSLKTLILANNQISTLV 171
L L N LT + + F N LHL +N ++++ + F L +LK L L NN++ L
Sbjct: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
Query: 172 SRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRINTQIYHLVPRLEE 231
F L L L N ++ + F + L++ LL + + ++ V L
Sbjct: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLTH 185
Query: 232 LDLGENLFKYL 242
LDL N K +
Sbjct: 186 LDLRGNRLKVM 196
Score = 45.6 bits (103), Expect = 5e-04
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 84 NLRELHIVNSNVPSIGQFSFWGLQNLRVLNLTHNNLTSVVADNFRGLINLTELHLDHNHI 143
+LR L++ + + + F GLQ+L+ L L +N + + F LINL L L++N +
Sbjct: 424 SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
Query: 144 EQMSSETFRHLTSLKTLILANNQISTL-VSRLFRMLAKLSILDLSDNP 190
+ F T+L L L NN S L V + L +DL +NP
Sbjct: 484 RSLPDNIFGG-TALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 35.9 bits (79), Expect = 0.38
Identities = 20/57 (35%), Positives = 29/57 (50%)
Query: 229 LEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMFGRNRELHVLTLSRN 285
L+ L LG N + F +L L++L L+GN L V+ +MF + L L L N
Sbjct: 401 LDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457
Score = 32.7 bits (71), Expect = 3.5
Identities = 26/112 (23%), Positives = 44/112 (39%)
Query: 160 LILANNQISTLVSRLFRMLAKLSILDLSDNPLTDLNPEVFKDIQHLRIFKCRRCLLRRIN 219
L L N ++ L F + L L +N L ++ F ++ L+ L +
Sbjct: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
Query: 220 TQIYHLVPRLEELDLGENLFKYLTSDEFISLKRLKKLKLDGNQLSVIVDNMF 271
+ + LE L N + + F L +LK L L+ N L + N+F
Sbjct: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVF 178
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.136 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,522,937
Number of Sequences: 224733
Number of extensions: 2797096
Number of successful extensions: 13500
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 540
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 5382
Number of HSP's gapped (non-prelim): 5004
length of query: 563
length of database: 73,234,838
effective HSP length: 94
effective length of query: 469
effective length of database: 52,109,936
effective search space: 24439559984
effective search space used: 24439559984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 68 (31.5 bits)
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