Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000675-TA|BGIBMGA000675-PA|IPR004837|Sodium/calcium
exchanger membrane region, IPR004481|K+-dependent Na+/Ca+ exchanger
related-protein
(422 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium exch... 225 2e-57
UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute car... 197 5e-49
UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium exch... 183 9e-45
UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca exch... 172 1e-41
UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila melanogast... 169 1e-40
UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p; ... 169 2e-40
UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.... 162 1e-38
UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to potassium-... 159 1e-37
UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute car... 159 2e-37
UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3 pr... 157 4e-37
UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep: Zgc:1... 155 2e-36
UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to potassium-... 152 1e-35
UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gamb... 145 2e-33
UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium exch... 144 3e-33
UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium exch... 143 9e-33
UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella ve... 140 8e-32
UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx... 139 1e-31
UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to Sodium/pot... 134 3e-30
UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella ve... 134 3e-30
UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila melanogaste... 134 5e-30
UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5 pr... 134 5e-30
UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve... 133 7e-30
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N... 133 1e-29
UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3; Euteleosto... 132 1e-29
UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1 (N... 132 1e-29
UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchang... 131 3e-29
UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchang... 131 4e-29
UniRef50_Q91WD8 Cluster: Solute carrier family 24 (Sodium/potass... 130 5e-29
UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:... 130 9e-29
UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2 pr... 130 9e-29
UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 - M... 129 1e-28
UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calci... 129 1e-28
UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus nor... 129 2e-28
UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome sh... 127 5e-28
UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias amure... 126 8e-28
UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3; Eut... 126 1e-27
UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4; Caenorhabditis|... 125 3e-27
UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchang... 122 2e-26
UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to potassium-... 121 4e-26
UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;... 121 4e-26
UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome s... 120 1e-25
UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5 pr... 120 1e-25
UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n... 119 1e-25
UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella ve... 118 2e-25
UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium excha... 118 4e-25
UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchang... 117 5e-25
UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium exch... 117 5e-25
UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isof... 110 6e-23
UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella ve... 108 3e-22
UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchang... 106 9e-22
UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep: Zgc... 104 5e-21
UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone sodiu... 102 2e-20
UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila melanogas... 101 5e-20
UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,... 87 6e-16
UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger prote... 85 3e-15
UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep: CG12061... 80 9e-14
UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 79 2e-13
UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus ... 79 2e-13
UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2; ... 78 4e-13
UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+ exchanger... 78 5e-13
UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis ... 76 2e-12
UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2; ... 75 4e-12
UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep: ... 73 1e-11
UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4; ... 73 1e-11
UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep: Slr... 73 2e-11
UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependen... 72 2e-11
UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium d... 72 2e-11
UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25; Ente... 71 8e-11
UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger related-... 70 1e-10
UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10
UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to potassium-... 68 5e-10
UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane pro... 68 5e-10
UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7 pre... 67 7e-10
UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; A... 67 9e-10
UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella ve... 66 2e-09
UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09
UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23; Gammaproteob... 66 2e-09
UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 66 2e-09
UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus... 64 5e-09
UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1; ... 63 2e-08
UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na... 63 2e-08
UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, who... 63 2e-08
UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger related-... 62 2e-08
UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2; Caeno... 62 2e-08
UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger related-... 62 3e-08
UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3; Caenor... 62 3e-08
UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6 pre... 60 8e-08
UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 60 1e-07
UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1; Lentisph... 60 1e-07
UniRef50_UPI000155609B Cluster: PREDICTED: similar to potassium-... 60 1e-07
UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger related-... 60 1e-07
UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21; ... 60 1e-07
UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128, w... 60 1e-07
UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1; Schizosa... 60 1e-07
UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6 pr... 59 2e-07
UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis th... 59 2e-07
UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; T... 58 3e-07
UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; F... 58 4e-07
UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1; ... 58 4e-07
UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 58 6e-07
UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1; ... 58 6e-07
UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6; Bacteria... 57 8e-07
UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, wh... 57 8e-07
UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella pneum... 57 1e-06
UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1; ... 57 1e-06
UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2; ... 56 1e-06
UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091... 56 1e-06
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein... 56 2e-06
UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family tr... 56 2e-06
UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2; Hyphomon... 56 2e-06
UniRef50_A1Z7I1 Cluster: CG14744-PA; n=2; Sophophora|Rep: CG1474... 56 2e-06
UniRef50_A4FZ20 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; M... 56 2e-06
UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1; ... 56 2e-06
UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; H... 56 2e-06
UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyce... 55 3e-06
UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger related-... 55 4e-06
UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1; Methanobrevib... 55 4e-06
UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1; Ar... 54 5e-06
UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, wh... 54 5e-06
UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2; ... 54 7e-06
UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protei... 54 9e-06
UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger antip... 54 9e-06
UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3; Flavobac... 54 9e-06
UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein... 54 9e-06
UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole gen... 54 9e-06
UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole geno... 54 9e-06
UniRef50_O83997 Cluster: Conserved hypothetical integral membran... 53 1e-05
UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium ion/cal... 53 1e-05
UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; C... 53 1e-05
UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like pro... 53 2e-05
UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 2e-05
UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45; Proteob... 52 3e-05
UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger antip... 52 3e-05
UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 52 3e-05
UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 3e-05
UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3; Poaceae|... 52 3e-05
UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2; ... 52 3e-05
UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces cap... 52 3e-05
UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 52 4e-05
UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1; ... 51 5e-05
UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related ... 51 5e-05
UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2; ... 51 5e-05
UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein... 51 7e-05
UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH04... 51 7e-05
UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger related-... 51 7e-05
UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23; Cyanobacteri... 51 7e-05
UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1; Algoriph... 51 7e-05
UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like p... 51 7e-05
UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6; ... 51 7e-05
UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 9e-05
UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 9e-05
UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; A... 50 2e-04
UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 2e-04
UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger related-... 50 2e-04
UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependen... 49 2e-04
UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Re... 49 2e-04
UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger related-... 49 3e-04
UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger related-... 49 3e-04
UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1; ... 49 3e-04
UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger related-... 49 3e-04
UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1; u... 49 3e-04
UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; M... 49 3e-04
UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_A0EBJ8 Cluster: Chromosome undetermined scaffold_88, wh... 48 4e-04
UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein... 48 5e-04
UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 48 5e-04
UniRef50_Q4Z7F0 Cluster: Calcium antiporter, putative; n=5; Plas... 48 5e-04
UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3... 48 6e-04
UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger related-... 48 6e-04
UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamm... 47 8e-04
UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2; ... 47 8e-04
UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precurs... 47 0.001
UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger prote... 47 0.001
UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001
UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 46 0.001
UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;... 46 0.001
UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1; ... 46 0.001
UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum sy... 46 0.001
UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3; Tetrah... 46 0.002
UniRef50_Q1JSU5 Cluster: Calcium antiporter, putative; n=3; Apic... 46 0.002
UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 46 0.002
UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P... 45 0.003
UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 45 0.003
UniRef50_UPI00015BD6AB Cluster: UPI00015BD6AB related cluster; n... 45 0.004
UniRef50_A5UZB1 Cluster: Sodium/calcium exchanger membrane regio... 45 0.004
UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:... 45 0.004
UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1; Thermoc... 45 0.004
UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep... 44 0.006
UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1; ... 44 0.006
UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger related-... 44 0.008
UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2; S... 44 0.008
UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2; ... 44 0.008
UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 44 0.010
UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3; R... 44 0.010
UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1; ... 44 0.010
UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter therma... 44 0.010
UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1; P... 43 0.013
UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger related-... 43 0.017
UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger related-... 43 0.017
UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, wh... 43 0.017
UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces cere... 43 0.017
UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 43 0.017
UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;... 42 0.023
UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces c... 42 0.023
UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;... 42 0.040
UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2; Oscillat... 42 0.040
UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Re... 42 0.040
UniRef50_A1Z8H3 Cluster: CG13223-PA; n=2; Sophophora|Rep: CG1322... 42 0.040
UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1; Haloa... 42 0.040
UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to sodium-cal... 41 0.053
UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein;... 41 0.053
UniRef50_Q5CSH9 Cluster: Calcium antiporter, Na/Ca exchange asso... 41 0.053
UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4; Halob... 41 0.053
UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeb... 41 0.071
UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;... 41 0.071
UniRef50_A4FI39 Cluster: K+-dependent Na+/Ca+ exchanger related-... 41 0.071
UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa... 41 0.071
UniRef50_A4RX12 Cluster: CaCA family transporter: sodium ion/pot... 41 0.071
UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.071
UniRef50_Q9HS69 Cluster: Cation antiporter; n=2; Halobacteriacea... 41 0.071
UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.093
UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida albi... 40 0.093
UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2; ... 40 0.093
UniRef50_Q3A9V0 Cluster: Sodium/calcium antiporter; n=1; Carboxy... 40 0.12
UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger related-... 40 0.12
UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.12
UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane regio... 40 0.16
UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:... 40 0.16
UniRef50_Q5CI48 Cluster: Cation exchanger; n=2; Cryptosporidium|... 40 0.16
UniRef50_Q29QD0 Cluster: AT15857p; n=2; Drosophila melanogaster|... 40 0.16
UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger related-... 39 0.22
UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula... 39 0.22
UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5; A... 39 0.22
UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;... 39 0.22
UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger related-... 39 0.28
UniRef50_A1Z7I2 Cluster: CG14743-PA; n=1; Drosophila melanogaste... 39 0.28
UniRef50_Q12424 Cluster: Putative cation exchanger YDL206W precu... 39 0.28
UniRef50_Q391I5 Cluster: Sodium/calcium exchanger membrane regio... 38 0.38
UniRef50_A5E210 Cluster: Putative uncharacterized protein; n=1; ... 38 0.38
UniRef50_Q9K8Y5 Cluster: Cation antiporter; n=1; Bacillus halodu... 38 0.50
UniRef50_Q6A563 Cluster: Sodium/calcium exchanger protein; n=3; ... 38 0.50
UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole geno... 38 0.50
UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;... 38 0.66
UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor (N... 38 0.66
UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2 precu... 37 0.87
UniRef50_A6TJL1 Cluster: Sodium/calcium exchanger membrane regio... 37 0.87
UniRef50_Q7PT92 Cluster: ENSANGP00000009511; n=1; Anopheles gamb... 37 0.87
UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein B14D6.... 37 0.87
UniRef50_Q6MGF3 Cluster: Putative uncharacterized protein B13C5.... 37 0.87
UniRef50_Q1E9Q8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.87
UniRef50_UPI0000DB6F63 Cluster: PREDICTED: similar to solute car... 36 1.5
UniRef50_A0M0N5 Cluster: Sodium/calcium exchanger protein; n=3; ... 36 1.5
UniRef50_Q2UEZ7 Cluster: Predicted protein; n=4; Aspergillus|Rep... 36 1.5
UniRef50_Q2S1K1 Cluster: Na+/Ca2+-exchanging protein; n=2; Bacte... 36 2.0
UniRef50_A7I3N4 Cluster: Cytochrome c553; n=2; Campylobacter hom... 36 2.0
UniRef50_A1SUD1 Cluster: Sodium/calcium exchanger membrane regio... 36 2.0
UniRef50_Q337V5 Cluster: Sodium/calcium exchanger protein, expre... 36 2.0
UniRef50_Q7QCY1 Cluster: ENSANGP00000016911; n=3; Coelomata|Rep:... 36 2.0
UniRef50_P32418 Cluster: Sodium/calcium exchanger 1 precursor (N... 36 2.0
UniRef50_Q0C4Z0 Cluster: Sodium/calcium exchanger; n=1; Hyphomon... 36 2.7
UniRef50_Q2R041 Cluster: Magnesium/proton exchanger, putative, e... 36 2.7
UniRef50_A7SLD3 Cluster: Predicted protein; n=1; Nematostella ve... 36 2.7
UniRef50_Q2UDY9 Cluster: K+-dependent Na+:Ca2+ antiporter; n=1; ... 36 2.7
UniRef50_UPI000065EB2A Cluster: Sodium/calcium exchanger 1 precu... 35 3.5
UniRef50_Q4S0T9 Cluster: Chromosome undetermined SCAF14779, whol... 35 3.5
UniRef50_A1G1U8 Cluster: Sodium/calcium exchanger membrane regio... 35 3.5
UniRef50_A2XD69 Cluster: Putative uncharacterized protein; n=1; ... 35 4.6
UniRef50_Q4T197 Cluster: Chromosome undetermined SCAF10698, whol... 34 6.1
UniRef50_Q30U71 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 6.1
UniRef50_Q18QE1 Cluster: Sodium/calcium exchanger membrane regio... 34 6.1
UniRef50_Q2QLY2 Cluster: Sodium/calcium exchanger protein, expre... 34 6.1
UniRef50_Q2GS93 Cluster: Putative uncharacterized protein; n=1; ... 34 6.1
UniRef50_A6C0C7 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
UniRef50_A2DCU6 Cluster: Clan PC, family C26, gamma-glutamyl hyd... 34 8.1
UniRef50_Q9C0K1 Cluster: Solute carrier family 39 member 8; n=29... 34 8.1
UniRef50_A5DAH8 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
>UniRef50_Q17BT5 Cluster: Potassium-dependent sodium-calcium
exchanger, putative; n=2; Culicidae|Rep:
Potassium-dependent sodium-calcium exchanger, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 549
Score = 225 bits (549), Expect = 2e-57
Identities = 108/227 (47%), Positives = 142/227 (62%), Gaps = 5/227 (2%)
Query: 8 LINKLELEDTTWHWKPWLRTRIEVV-DNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFL 66
L ++ELE TWHW P+ R V+ D E++C G +ID PD +FT EQ QGA +
Sbjct: 48 LDERIELEKITWHWYPYRRINYVVLEDGQKVELLCDQGSAIDELPDDVFTQEQRLQGAII 107
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
L+ + IY FTLLA + +YF+P VE ICEDLK+ Q+VAAATFM++A + PEFF N IST
Sbjct: 108 LHFIGAIYFFTLLAYIVGEYFLPSVECICEDLKLTQDVAAATFMAIAGTIPEFFTNTIST 167
Query: 127 FLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
F+ +SDMGIGTI+GS LFN P+ +D P+TRD +++ +ISVLV F
Sbjct: 168 FIADSDMGIGTIMGSLLFNTLGVACLAGLACKKPVQLDWWPITRDCIVFAFHISVLVGFA 227
Query: 187 WDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI----WAACCK 229
WDG+I W+E+MV IL YFVVMF + L K W C +
Sbjct: 228 WDGRIYWYESMVFVILLFTYFVVMFQNKPIMKLAKKYIEVKWNLCAR 274
Score = 138 bits (335), Expect = 2e-31
Identities = 65/141 (46%), Positives = 91/141 (64%), Gaps = 1/141 (0%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ VMG+TFLA GGC+PEA S ++ R G G +GVSNALGANSL+I+F+LGLPW
Sbjct: 408 GYTLGIPDGVMGLTFLAMGGCMPEAISAVLIIRTGNGAVGVSNALGANSLSIVFSLGLPW 467
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
IRTV+ + N V+I S G+ + ++V++IGK+ LRR +G+ L
Sbjct: 468 FIRTVA-DGASTTNAYVIIASHGMQYSIIALLFAVGSLYVVIYIGKYKLRRRIGVALIFC 526
Query: 397 YVVFIVFAILVELGIIFDRNV 417
YV+ + F +L EL I F +
Sbjct: 527 YVILVTFMLLNELDIFFPSGI 547
>UniRef50_UPI0000D56292 Cluster: PREDICTED: similar to solute
carrier family 24, member 5; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to solute carrier
family 24, member 5 - Tribolium castaneum
Length = 488
Score = 197 bits (480), Expect = 5e-49
Identities = 89/175 (50%), Positives = 124/175 (70%), Gaps = 3/175 (1%)
Query: 41 CATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKI 100
CA+ S + FP +FT+ Q+ +G +L GIY FTLLAI+C++YF+PCVE ICE L +
Sbjct: 45 CAS--SSEDFPS-MFTETQVEKGGIILVFCIGIYCFTLLAIICDNYFLPCVEKICEALNL 101
Query: 101 PQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTP 160
+VAAATFMSVATS PE FVN+I TF+TESD+GIGT+VGS+LFN TP
Sbjct: 102 SHDVAAATFMSVATSTPELFVNIIGTFITESDIGIGTVVGSSLFNTLGVASLGSLAASTP 161
Query: 161 IAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMK 215
+ + P++RDV+IY+++I +LV WDG I W+E +VL ++Y +YF VMF +++
Sbjct: 162 VQLHWWPISRDVIIYILSILLLVGITWDGYIYWYEGLVLFLVYFIYFTVMFQNVR 216
Score = 123 bits (297), Expect = 8e-27
Identities = 60/134 (44%), Positives = 88/134 (65%), Gaps = 4/134 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+ F IP++V+G+TFLA GGCLPEA SI IMSRRGEG +GVSN+LGAN++ IL +LG+PW
Sbjct: 346 GNMFKIPDAVLGLTFLAAGGCLPEAISITIMSRRGEGSMGVSNSLGANTMNILLSLGMPW 405
Query: 337 LIRTVSLEIQGAENTA-VLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGI 395
++T+ + G + A + I+S ++F ++ + KF + R VG +L
Sbjct: 406 FLKTI---VMGTDEQAFIRISSGSLEFTISALIPVAIILYLTFYFNKFQMCRKVGFILIS 462
Query: 396 LYVVFIVFAILVEL 409
+Y V I+ AIL E+
Sbjct: 463 VYTVCIILAILGEM 476
>UniRef50_Q17BT4 Cluster: Potassium-dependent sodium-calcium
exchanger, putative; n=1; Aedes aegypti|Rep:
Potassium-dependent sodium-calcium exchanger, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 520
Score = 183 bits (445), Expect = 9e-45
Identities = 87/193 (45%), Positives = 126/193 (65%), Gaps = 4/193 (2%)
Query: 39 VVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDL 98
VVC S+D P +F+ + GA +L+ + IY FT+LA VC++YF+P VE ICEDL
Sbjct: 59 VVCVLTTSMDDLPPDLFSKTERLNGAIILHFLAAIYFFTILAYVCSEYFLPSVEYICEDL 118
Query: 99 KIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXX 158
+ ++VAAATFM+ ATS PEFF N IST + +SDMG+GTI+GS LFN
Sbjct: 119 HLSEDVAAATFMATATSMPEFFTNTISTLVVDSDMGLGTIMGSMLFNTLGVAALVGLLTK 178
Query: 159 TPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS--MK- 215
+ + +D P+TRD +I +++ S LV+ +WD ++ W+E++V +LY+LYF+VMF + MK
Sbjct: 179 SHVKLDWWPLTRDSIIVIISTSSLVSCLWDERVYWYESLVFVVLYVLYFLVMFQNDRMKR 238
Query: 216 -AFVLIDKIWAAC 227
A LI+ W C
Sbjct: 239 IAVSLIEDRWNLC 251
Score = 141 bits (341), Expect = 4e-32
Identities = 67/137 (48%), Positives = 92/137 (67%), Gaps = 1/137 (0%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF +PE+VMG+TFLAFGGC+PEA S + R+G G +GVSN+LGAN+LAILF+LGLPW
Sbjct: 379 GSTFDVPETVMGLTFLAFGGCMPEAVSAITVIRKGNGSMGVSNSLGANTLAILFSLGLPW 438
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
IR + +E + INS G+ + ++VL++ KFTLR+ VG+ L I
Sbjct: 439 FIRNM-MEGGATTGAYIEINSYGMQYSVLALFLAVGILYLVLYLSKFTLRKLVGLALLIA 497
Query: 397 YVVFIVFAILVELGIIF 413
Y++ + F ILVEL + F
Sbjct: 498 YLIIVSFMILVELDVFF 514
>UniRef50_UPI000051A586 Cluster: PREDICTED: similar to Na-Ca
exchanger 5; n=1; Apis mellifera|Rep: PREDICTED: similar
to Na-Ca exchanger 5 - Apis mellifera
Length = 489
Score = 172 bits (419), Expect = 1e-41
Identities = 79/181 (43%), Positives = 116/181 (64%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T SI FP+ +FT EQ R GA +L+ G+Y F L A VC+DY +P V+ IC L I
Sbjct: 27 TDRSIHDFPEDLFTYEQRRHGAVILHAFLGLYCFLLTAFVCHDYLLPAVDRICISLNIST 86
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATF+++A+S PE FVNVI TFLTESD+G GT+VGSA+F+ I+
Sbjct: 87 DVAGATFLAMASSFPELFVNVIGTFLTESDLGAGTVVGSAVFDTFATPACGALMTFYAIS 146
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDK 222
++ + ++RD L+Y++++ LV +WD +I W+EAM+L IL+ Y +++F + DK
Sbjct: 147 LEWQVLSRDCLMYVISVGTLVIIMWDAKIQWYEAMILLILFCFYLILLFCGKHIRLCYDK 206
Query: 223 I 223
I
Sbjct: 207 I 207
Score = 111 bits (266), Expect = 4e-23
Identities = 57/143 (39%), Positives = 84/143 (58%), Gaps = 6/143 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G IP+S+MG+TFLA GG +PE SI I++R+G+G + +SN LGAN L IL LGLPW
Sbjct: 350 GDIIGIPDSIMGLTFLAAGGNMPEVASIVILARQGDGNMAMSNTLGANILDILLCLGLPW 409
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
+I+ + E V I S + + + V+ KF L + VGI+ L
Sbjct: 410 MIKCL------MEKRYVEIESGALKYSVFSTIICVIVLYTVIACFKFKLNKKVGIICLFL 463
Query: 397 YVVFIVFAILVELGIIFDRNVEL 419
Y++F++FAIL+EL + F N+ +
Sbjct: 464 YMIFLIFAILIELNVFFIINLPM 486
>UniRef50_Q5LJX8 Cluster: CG2893-PC.3; n=4; Drosophila
melanogaster|Rep: CG2893-PC.3 - Drosophila melanogaster
(Fruit fly)
Length = 542
Score = 169 bits (411), Expect = 1e-40
Identities = 88/235 (37%), Positives = 130/235 (55%), Gaps = 11/235 (4%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +ID FP +F++ Q + GA +L+V+ +Y F LA+VC++YF+P VE IC L +
Sbjct: 23 TQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSN 82
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ ATS PE FVNVI TF+TE D+G+GTIVGSA+FN I
Sbjct: 83 DVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIP 142
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDK 222
+D P+TRD + Y V +++L+ + D +++W+EA++L LY +Y VM+ DK
Sbjct: 143 LDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMY--------FDK 194
Query: 223 IWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNG 277
+ C K G + S I K N+ P + + A + NG
Sbjct: 195 TFQKCAK---GGVKQARSRSRSSNCSIHTKNSNEKEPELVENRICQNMANIQLNG 246
Score = 121 bits (292), Expect = 3e-26
Identities = 61/146 (41%), Positives = 89/146 (60%), Gaps = 3/146 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFLA G +PEA S I+++RG G +G+ N++G+N+ IL LG+PW
Sbjct: 397 GDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPW 456
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI+ V IQ +N V INSAG+++ ++ KF L + VG ++
Sbjct: 457 LIKAVFFPIQPGQN-YVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVM 515
Query: 397 YVVFIVFAILVELGIIFDRNVELSSC 422
Y+VF+VFA L+EL + F V L +C
Sbjct: 516 YLVFMVFASLIELNVFF--RVNLPTC 539
Score = 38.3 bits (85), Expect = 0.38
Identities = 20/55 (36%), Positives = 29/55 (52%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ +I + LKIP +V TF++ TS PE +VI MGI +GS F+
Sbjct: 393 ITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFD 447
>UniRef50_UPI00015B4954 Cluster: PREDICTED: similar to RE34149p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
RE34149p - Nasonia vitripennis
Length = 542
Score = 169 bits (410), Expect = 2e-40
Identities = 72/166 (43%), Positives = 108/166 (65%)
Query: 46 SIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVA 105
SI+ FP+ +FT +Q +QGA L ++ FG+Y F L A VCNDY +P ++ IC DL+I +VA
Sbjct: 60 SIEDFPEDLFTLQQRQQGAILFHIFFGLYCFLLTAFVCNDYLLPALDCICADLRISADVA 119
Query: 106 AATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDM 165
ATF++ A+ PE FVNV+ TFLTESD+G+G +VG A+FN I +
Sbjct: 120 GATFLATASCFPELFVNVVGTFLTESDLGVGAVVGGAVFNTFATPAVGALFAAKGIQLQW 179
Query: 166 RPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
++RD +IY ++ VLV +WDG + W+E+++L L+ YF ++F
Sbjct: 180 HILSRDCVIYSFSVGVLVLVMWDGLVTWYESVILLFLFASYFTLLF 225
Score = 99.1 bits (236), Expect = 2e-19
Identities = 55/143 (38%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFL+ GG LPE SI I+SR+G G + +SN +GAN+L IL L LPW
Sbjct: 405 GDTVGIPDSVMGITFLSAGGNLPEMVSIVILSRQGHGDMAMSNTIGANTLDILLCLSLPW 464
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
IR + G + T V S+ + + + V + F L + VGI+ I+
Sbjct: 465 AIRNF---MTGKDVTIV---SSALVYSNLSIIVCVAGFYAVTALYGFILNKRVGIICLIM 518
Query: 397 YVVFIVFAILVELGIIFDRNVEL 419
Y +F+V ++++EL + F N+ +
Sbjct: 519 YCLFLVISVMMELNVFFFVNLPM 541
>UniRef50_UPI0000D56294 Cluster: PREDICTED: similar to CG2893-PB.3;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG2893-PB.3 - Tribolium castaneum
Length = 480
Score = 162 bits (394), Expect = 1e-38
Identities = 73/173 (42%), Positives = 111/173 (64%), Gaps = 4/173 (2%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +ID FP FT+++ + GA +++VV +Y F LA+VC+ +F+P VE IC L +
Sbjct: 6 TPPAIDDFPRDFFTEKERQDGAVVVHVVVSLYLFVALAVVCDKFFVPAVEKICHALNMSA 65
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXX----XXXXXXX 158
+VA ATFM+ ATS PE FVNVI TF+TE D+G+GTIVGSA+FN
Sbjct: 66 DVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGLCGV 125
Query: 159 TPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
+ +D P+TRD L Y + +S+L+ + D +++W+EA+ L +LY +Y ++M+
Sbjct: 126 KVVPLDWWPLTRDCLAYGITVSILICIIHDERVEWYEALTLVLLYTVYILIMY 178
Score = 112 bits (269), Expect = 2e-23
Identities = 56/146 (38%), Positives = 87/146 (59%), Gaps = 3/146 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFLA G +PEA S I++++G G +G+SN++G+N+ IL LGLPW
Sbjct: 336 GDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHGSMGISNSIGSNTFDILLCLGLPW 395
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+ + ++ V INSAGI++ ++V + KF L + VG + ++
Sbjct: 396 FIKATFMPTIAGKHW-VGINSAGIEYSAISLLSSLLLLYLVFAVNKFRLDKRVGRICLLM 454
Query: 397 YVVFIVFAILVELGIIFDRNVELSSC 422
Y +F++ A L+EL F V L +C
Sbjct: 455 YAIFLILASLIELNAFF--RVNLPTC 478
Score = 39.5 bits (88), Expect = 0.16
Identities = 20/55 (36%), Positives = 29/55 (52%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ +I + LKIP +V TF++ TS PE +VI MGI +GS F+
Sbjct: 332 ITIIGDTLKIPDSVMGITFLAAGTSIPEAVSSVIVAKQGHGSMGISNSIGSNTFD 386
>UniRef50_UPI0000E4921D Cluster: PREDICTED: similar to
potassium-dependent Na/Ca exchanger NCKX3; n=2;
Deuterostomia|Rep: PREDICTED: similar to
potassium-dependent Na/Ca exchanger NCKX3 -
Strongylocentrotus purpuratus
Length = 570
Score = 159 bits (386), Expect = 1e-37
Identities = 70/175 (40%), Positives = 112/175 (64%), Gaps = 1/175 (0%)
Query: 37 HEV-VCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELIC 95
HEV + T +I+ FP +FT+EQ +GAF+ + + +Y F LAIVC+DYF+ +E IC
Sbjct: 70 HEVEMNCTPSTIEEFPGDLFTEEQRAKGAFITHAICAVYMFIALAIVCDDYFVSSLEKIC 129
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E+L + ++VA ATFM+ +S PE F +VI F+ + D+G+GTIVGSA+FN
Sbjct: 130 ENLSLTEDVAGATFMAAGSSAPELFTSVIGVFIAKGDVGVGTIVGSAVFNILVIIGLCGL 189
Query: 156 XXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ + P+ RD L+Y +++ LV + DG I+W+EA+V+ ++Y+ Y ++M
Sbjct: 190 FAGQVVHLSWWPLFRDTLVYAISVVTLVLVIRDGYINWYEALVMLLMYLCYVIIM 244
Score = 99.1 bits (236), Expect = 2e-19
Identities = 47/135 (34%), Positives = 79/135 (58%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
GHT IP+++MG+TFLA G +P+A + +++R G G + VSN++G+N IL L LPW
Sbjct: 429 GHTLHIPDTIMGITFLAAGTSVPDAIASLLVAREGLGDMAVSNSIGSNVFDILIGLALPW 488
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T + + T + INS G+ + + + K+ L + +G++L
Sbjct: 489 FIKTAFV----SYGTRIKINSKGLLYSVLLLFASVTATILAIHFNKWRLDKRLGVLLTCF 544
Query: 397 YVVFIVFAILVELGI 411
YVVF+ F+I+VE+ +
Sbjct: 545 YVVFLSFSIMVEMNV 559
>UniRef50_UPI0000DB799E Cluster: PREDICTED: similar to solute
carrier family 24, member 5; n=1; Apis mellifera|Rep:
PREDICTED: similar to solute carrier family 24, member 5
- Apis mellifera
Length = 439
Score = 159 bits (385), Expect = 2e-37
Identities = 70/168 (41%), Positives = 108/168 (64%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +I FP T EQ + G L++ V IY F LLAIVC+D+F+P ++ IC+ + + +
Sbjct: 25 TPPAIKEFPSDGLTREQRQLGFILIHFVIAIYMFLLLAIVCDDFFVPSIKKICDKINVSE 84
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA AT M+ ATS PE F+N++ TF+TE D+G+GTIVGSA+FN +
Sbjct: 85 DVAGATIMATATSSPELFINIVGTFITEGDLGVGTIVGSAVFNILAVPACCGLFANQILN 144
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
++ PVTRD + Y + + +L+ + DG+I+W+EA++L + Y LY +VM
Sbjct: 145 LEAWPVTRDTIAYAITVFLLILTLRDGRIEWYEALILVLSYFLYILVM 192
Score = 118 bits (285), Expect = 2e-25
Identities = 57/143 (39%), Positives = 89/143 (62%), Gaps = 1/143 (0%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF IP+S+MG+TFLA G +PEA S I++ +G G +G+SN++G+N +L LGLPW
Sbjct: 295 GDTFRIPDSIMGLTFLAAGMSVPEAVSSVIVANQGHGAMGISNSIGSNVFDVLLCLGLPW 354
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++ +L + N V INS G+ + ++ L +GKF L R+VGI+ +
Sbjct: 355 FLK-AALFSKEPGNHYVTINSQGLVYSSISLFSTLTVLYLSLLVGKFKLTRSVGIICLTM 413
Query: 397 YVVFIVFAILVELGIIFDRNVEL 419
Y++F+VFA ++EL I F N+ +
Sbjct: 414 YIIFLVFASILELNIFFMVNLPI 436
Score = 33.9 bits (74), Expect = 8.1
Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 74 YTFTLLAIVCNDYFIPCVELICED-LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
+ ++ I Y + V + D +IP ++ TF++ S PE +VI
Sbjct: 273 FIMCIIWIASTSYIVGWVITVIGDTFRIPDSIMGLTFLAAGMSVPEAVSSVIVANQGHGA 332
Query: 133 MGIGTIVGSALFN 145
MGI +GS +F+
Sbjct: 333 MGISNSIGSNVFD 345
>UniRef50_Q9HC58 Cluster: Sodium/potassium/calcium exchanger 3
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3); n=55;
Eumetazoa|Rep: Sodium/potassium/calcium exchanger 3
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) - Homo
sapiens (Human)
Length = 644
Score = 157 bits (382), Expect = 4e-37
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 3e-15
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
>UniRef50_Q567G1 Cluster: Zgc:112072; n=4; Danio rerio|Rep:
Zgc:112072 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 569
Score = 155 bits (377), Expect = 2e-36
Identities = 75/189 (39%), Positives = 115/189 (60%), Gaps = 2/189 (1%)
Query: 26 RTRIEVVDNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCND 85
R V DN E C T +I FP+ +FT++Q QGA LL++ +Y F LAIVC+D
Sbjct: 46 RLMATVGDNETQEKNC-TAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDD 104
Query: 86 YFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
YF+ +E ICE L + ++VA ATFM+ +S PE F ++I F+T D+G+GTIVGSA+FN
Sbjct: 105 YFVTSLEKICEKLHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFN 164
Query: 146 XXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
+ + V RD Y++++ L+ F++D +I W+E++VL ++Y+
Sbjct: 165 ILCIIGVCGIFAGQVVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLG 224
Query: 206 YFVVM-FNS 213
Y +VM FN+
Sbjct: 225 YIIVMKFNT 233
Score = 88.6 bits (210), Expect = 3e-16
Identities = 44/135 (32%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 425 GYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 484
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T+++ + V INS G+ + + + + ++ L +GI + +L
Sbjct: 485 GIQTMAVNY----GSVVKINSRGLVYSVVLLLGSVALTVLGIHVNRWRLDLRLGIYVLVL 540
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I++E +
Sbjct: 541 YAVFLTFSIMIEYNV 555
>UniRef50_UPI00015B4956 Cluster: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger, putative;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger, putative -
Nasonia vitripennis
Length = 561
Score = 152 bits (369), Expect = 1e-35
Identities = 70/171 (40%), Positives = 107/171 (62%), Gaps = 1/171 (0%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T SI FP T Q + G +++V+ Y F LLAIVC+D+F+P + IC+ + + +
Sbjct: 97 TPPSIKEFPSDGLTRYQRQHGFIVIHVIIACYAFFLLAIVCDDFFVPSIVKICDKIGMSK 156
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ A+S PE F+N++ TF+TE D+G+GTIVGSA+FN +
Sbjct: 157 DVAGATFMAAASSSPELFINIVGTFVTEGDLGVGTIVGSAVFNILAVPACCGLFASQVLD 216
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+D P++RD L Y V + +L+ + DG+I+W+EA +L + YI Y + M FN
Sbjct: 217 LDWWPISRDSLAYGVTVLLLIFTLHDGRIEWYEAFILVLFYIFYILAMVFN 267
Score = 104 bits (249), Expect = 5e-21
Identities = 52/137 (37%), Positives = 78/137 (56%), Gaps = 1/137 (0%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFLA G +PEA S I++ +G G +G+SN++G+N +L LGLPW
Sbjct: 417 GDTLMIPDSVMGLTFLAAGMSVPEAVSSVIVTNQGHGTMGISNSIGSNVFDVLLCLGLPW 476
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+ E+ V INS G+ + + VL ++ L + VG + +
Sbjct: 477 FIKASFFPTAAGEH-FVQINSEGLIYSSVSLMSTLILLYTVLACNRYKLDKRVGFICLGM 535
Query: 397 YVVFIVFAILVELGIIF 413
Y +F+VFA L+EL + F
Sbjct: 536 YSIFLVFAALIELNVFF 552
Score = 37.1 bits (82), Expect = 0.87
Identities = 19/55 (34%), Positives = 29/55 (52%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ +I + L IP +V TF++ S PE +VI T MGI +GS +F+
Sbjct: 413 ITIIGDTLMIPDSVMGLTFLAAGMSVPEAVSSVIVTNQGHGTMGISNSIGSNVFD 467
>UniRef50_Q7PSJ7 Cluster: ENSANGP00000012714; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000012714 - Anopheles gambiae
str. PEST
Length = 386
Score = 145 bits (352), Expect = 2e-33
Identities = 71/139 (51%), Positives = 94/139 (67%), Gaps = 5/139 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+TF IP++VMGMTFLAFGGC+PEA S + RRG G +GVSN+LGAN+LAILF+LGLPW
Sbjct: 245 GNTFGIPDTVMGMTFLAFGGCMPEAASAITLIRRGNGAMGVSNSLGANTLAILFSLGLPW 304
Query: 337 LIRTVSLEIQGAENTA--VLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLG 394
IRT+ I G +T + I S GI + + VL++ K+TLR+ VG+ L
Sbjct: 305 FIRTM---IDGGPSTGAYIAIQSYGIQYSVLALFGAIFTLYAVLYVAKYTLRKMVGLALA 361
Query: 395 ILYVVFIVFAILVELGIIF 413
+ Y+V + F ILVEL + F
Sbjct: 362 VGYLVIVTFMILVELDVFF 380
Score = 131 bits (316), Expect = 4e-29
Identities = 59/100 (59%), Positives = 76/100 (76%)
Query: 46 SIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVA 105
S+D P +FT+EQ QGA +L+ + IY F LLA VC++YF+P VE +CEDLK+ Q+VA
Sbjct: 2 SLDDLPPDLFTEEQRLQGAIVLHFLAAIYFFMLLAYVCSEYFLPSVECLCEDLKLSQDVA 61
Query: 106 AATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
AATFM+ ATS PEFF N IST +SD+G+GTI+GS LFN
Sbjct: 62 AATFMATATSMPEFFTNTISTLAVDSDIGVGTIMGSMLFN 101
>UniRef50_Q17BT6 Cluster: Potassium-dependent sodium-calcium
exchanger, putative; n=3; Endopterygota|Rep:
Potassium-dependent sodium-calcium exchanger, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 542
Score = 144 bits (350), Expect = 3e-33
Identities = 64/168 (38%), Positives = 104/168 (61%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +I FP FT E+ + G ++++ Y F LLAIVC+DYF+P +EL+C+ L++ +
Sbjct: 98 TPAAIFEFPSDGFTREERKHGWITVHLLIACYCFWLLAIVCDDYFVPAIELMCKKLQVKE 157
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
++A ATFM+ A+S PE F+N + TF+T+ D+G+G +VGSA+FN +
Sbjct: 158 DIAGATFMAAASSSPELFINCVGTFITKGDIGVGAVVGSAVFNILAVPAVCGLFGGQVVQ 217
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ PVTRD ++Y + + L+ + DG++ W+EA +L Y+LY M
Sbjct: 218 LRWWPVTRDSMMYGMAVIGLITVLNDGKVMWYEATILVSAYVLYITAM 265
Score = 108 bits (259), Expect = 3e-22
Identities = 55/146 (37%), Positives = 84/146 (57%), Gaps = 3/146 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFLA G +PEA S I++ +G G +G+SN++G+N+ IL LGLPW
Sbjct: 398 GDTMDIPDSVMGLTFLAAGTSVPEAVSSIIVTNQGHGEMGISNSIGSNTFDILLCLGLPW 457
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI+ ++ EN V +NS+G+ + +I + KF L VG+ +
Sbjct: 458 LIKALAFPAIPGENW-VALNSSGLTYSAISLLSTLCGLYIAFWSNKFKLDWKVGLTCTSM 516
Query: 397 YVVFIVFAILVELGIIFDRNVELSSC 422
Y+ F+ + L+EL + F V L +C
Sbjct: 517 YIAFLTVSSLIELNVFF--KVNLPTC 540
Score = 39.1 bits (87), Expect = 0.22
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 86 YFIP-CVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
YF+ + ++ + + IP +V TF++ TS PE ++I T +MGI +GS F
Sbjct: 388 YFVAFLITVVGDTMDIPDSVMGLTFLAAGTSVPEAVSSIIVTNQGHGEMGISNSIGSNTF 447
Query: 145 N 145
+
Sbjct: 448 D 448
>UniRef50_Q17BY6 Cluster: Potassium-dependent sodium-calcium
exchanger; n=5; Coelomata|Rep: Potassium-dependent
sodium-calcium exchanger - Aedes aegypti (Yellowfever
mosquito)
Length = 207
Score = 143 bits (346), Expect = 9e-33
Identities = 72/164 (43%), Positives = 102/164 (62%), Gaps = 1/164 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP+ +FT EQ R GA +L+++ IY F LAIVC+++F+P +++I E L I +VA ATF
Sbjct: 1 FPEDLFTLEQRRNGAVVLHILGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 60
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F +VI F++ D+GIGTIVGSA+FN T + + P+
Sbjct: 61 MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTLLTLTWWPLF 120
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
RD Y V++ L+ F D I+W+EA+VL I+YI Y V M FN
Sbjct: 121 RDCTFYSVSLLTLIYFFRDNSIEWWEALVLFIIYIAYAVFMKFN 164
>UniRef50_A7SW69 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 490
Score = 140 bits (338), Expect = 8e-32
Identities = 63/169 (37%), Positives = 102/169 (60%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +I FPD FT Q ++GA +L + +Y F +AIVC+DYF+PC+E+IC+ L +
Sbjct: 3 TPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGLQT 62
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM++ +S PE F +VI F+T+ D+G+GTI+GSA+FN T +
Sbjct: 63 DVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTVLY 122
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
+ P+ RD + Y+ ++ L+ + D + W EA + Y +Y ++M+
Sbjct: 123 LAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMY 171
Score = 98.7 bits (235), Expect = 3e-19
Identities = 46/133 (34%), Positives = 81/133 (60%), Gaps = 4/133 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+TF IP+SVMG++ +AFG +P+ S ++R+G+G + VS+ +G+N IL LG+PW
Sbjct: 347 GYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVGSNVFDILLCLGIPW 406
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI+T E +++V+INS G+ I+++ K+TL + VG + +
Sbjct: 407 LIKTTVWEY----DSSVVINSHGLFISCFFILGSIAVTLIIIWYYKWTLNKKVGCIYLVF 462
Query: 397 YVVFIVFAILVEL 409
Y +F+ +++VE+
Sbjct: 463 YFIFMSISVVVEM 475
>UniRef50_Q9U6A0 Cluster: Sodium/potassium/calcium exchanger Nckx30C
(Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C); n=7;
Diptera|Rep: Sodium/potassium/calcium exchanger Nckx30C
(Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) -
Drosophila melanogaster (Fruit fly)
Length = 888
Score = 139 bits (337), Expect = 1e-31
Identities = 67/161 (41%), Positives = 99/161 (61%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP +FT EQL GA +L+++ IY F LAIVC+++F+P +++I E L I +VA ATF
Sbjct: 318 FPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATF 377
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F +VI F++ D+GIGTIVGSA+FN T +++ P+
Sbjct: 378 MAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLF 437
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
RD Y +++ VL+ F D +I W+EA++L +YI Y M
Sbjct: 438 RDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFM 478
Score = 65.7 bits (153), Expect = 2e-09
Identities = 38/136 (27%), Positives = 70/136 (51%), Gaps = 6/136 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP VMG+TFLA G +P+ + I++R+G G + VS+++G+N + L +PW
Sbjct: 755 GDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPW 814
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ + I GA V +NS G+ + + ++ + + +G + +L
Sbjct: 815 LLYGI---IYGA---PVEVNSVGMVCSITILFMMLVFVVMSIACFRWRMNKGLGFTMFLL 868
Query: 397 YVVFIVFAILVELGII 412
Y F+ +++ E +I
Sbjct: 869 YFAFVAVSLMFEYDVI 884
Score = 34.7 bits (76), Expect = 4.6
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 99 KIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+IP V TF++ TS P+ +VI DM + + VGS +F+
Sbjct: 759 RIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFD 805
>UniRef50_UPI0000519AB6 Cluster: PREDICTED: similar to
Sodium/potassium/calcium exchanger
(Na(+)/K(+)/Ca(2+)-exchange protein); n=2;
Endopterygota|Rep: PREDICTED: similar to
Sodium/potassium/calcium exchanger
(Na(+)/K(+)/Ca(2+)-exchange protein) - Apis mellifera
Length = 658
Score = 134 bits (325), Expect = 3e-30
Identities = 65/168 (38%), Positives = 98/168 (58%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T + FP +FT Q R+GA +L+V+ +Y F LAIVC+++F+P +++I E L+I
Sbjct: 105 TEEKAPLFPQDLFTVHQRRRGAVILHVIGVVYMFVALAIVCDEFFVPSLDVIIEKLEIAD 164
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ S PE F ++I F++ D+GIGTIVGSA+FN T ++
Sbjct: 165 DVAGATFMAAGGSAPELFTSIIGVFVSFDDVGIGTIVGSAVFNILFVIGMCAIFSRTVLS 224
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ P+ RD Y ++ L+ F D I W+EA+VL Y+ Y M
Sbjct: 225 LTWWPLFRDCTFYSASLLTLIYFFRDNYIHWYEALVLFGFYLAYVSFM 272
Score = 63.7 bits (148), Expect = 9e-09
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP VMG+TFLA G +P+ + I++R+G G + VS+++G+N + L +PW
Sbjct: 525 GDTVRIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPVPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ + I G V +NS G+ + + K+ + + +G + +L
Sbjct: 585 LLYGL---IYG---RPVEVNSVGMVCSIAILFCMLLFVILSIACFKWRMNKGLGFTMFLL 638
Query: 397 YVVFIVFAILVE 408
Y VF+ +++ E
Sbjct: 639 YFVFVAVSLMFE 650
Score = 35.5 bits (78), Expect = 2.7
Identities = 16/50 (32%), Positives = 27/50 (54%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ ++IP V TF++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 DTVRIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFD 575
>UniRef50_A7RKL4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 429
Score = 134 bits (325), Expect = 3e-30
Identities = 56/166 (33%), Positives = 98/166 (59%)
Query: 46 SIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVA 105
+I+ FP + T +Q G +L+V+F ++ F L +VC D+F+ + I L + +VA
Sbjct: 5 NIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLKPDVA 64
Query: 106 AATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDM 165
ATFM+V +S P F+ +IS F TE D+G+GTIVGS +FN + +
Sbjct: 65 GATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTLQLAC 124
Query: 166 RPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
P++RD +Y+ ++ VL+ ++D ++ W+E ++ I+Y +Y V+M+
Sbjct: 125 YPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMY 170
Score = 90.2 bits (214), Expect = 9e-17
Identities = 47/132 (35%), Positives = 75/132 (56%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T+ IPE VMGMTFLA G LP+A + +++++G G + VSN +G+N +L LG+PW
Sbjct: 292 GYTYTIPECVMGMTFLAAGSSLPDAIASLVVAKQGSGDMAVSNCIGSNVFDML-CLGIPW 350
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI++ L+ V+I S I F ++++ K+ L VGI I+
Sbjct: 351 LIKSAFLQ----PGKPVVIQSENIFFTSAMLIGSIAVTFLLIQFNKWKLNVKVGIAFLIM 406
Query: 397 YVVFIVFAILVE 408
Y +F++ A +E
Sbjct: 407 YFLFLIVATYIE 418
Score = 35.1 bits (77), Expect = 3.5
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 71 FGIYTFTLLAI---VCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF 127
F + TFT+ I V + + + V +I IP+ V TF++ +S P+ +++
Sbjct: 265 FYLVTFTVAVIWMAVLSYFLVWMVAIIGYTYTIPECVMGMTFLAAGSSLPDAIASLVVAK 324
Query: 128 LTESDMGIGTIVGSALFN 145
DM + +GS +F+
Sbjct: 325 QGSGDMAVSNCIGSNVFD 342
>UniRef50_Q7PLW4 Cluster: CG17167-PA; n=3; Drosophila
melanogaster|Rep: CG17167-PA - Drosophila melanogaster
(Fruit fly)
Length = 441
Score = 134 bits (323), Expect = 5e-30
Identities = 62/102 (60%), Positives = 78/102 (76%), Gaps = 1/102 (0%)
Query: 44 GDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQN 103
G +D F D +FT +QLRQG +L+V +Y F LLAI+CNDYF+P VE ICEDL + ++
Sbjct: 63 GSPMDEFAD-LFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKD 121
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
VAAATFM+ ATS PEFF N IST + ESDMG+GTI+GS +FN
Sbjct: 122 VAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFN 163
Score = 108 bits (259), Expect = 3e-22
Identities = 57/140 (40%), Positives = 78/140 (55%), Gaps = 3/140 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G +P VMG+TFLA G +PEA S I R GE GIGVSN+LGANSLAIL +LG+PW
Sbjct: 302 GVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPW 361
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+ I + + GI++ +I+L + L + VG+ L +
Sbjct: 362 FIKNC---IHYGTGEPQQVGTQGIEYNILILIISTMALFIILSFSGYRLTKRVGVALFTV 418
Query: 397 YVVFIVFAILVELGIIFDRN 416
Y VFIV IL+E+ + F R+
Sbjct: 419 YGVFIVLQILIEMNVFFPRD 438
>UniRef50_Q71RS6 Cluster: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=20;
Euteleostomi|Rep: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Homo
sapiens (Human)
Length = 500
Score = 134 bits (323), Expect = 5e-30
Identities = 59/179 (32%), Positives = 102/179 (56%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP+G FT ++ R G ++Y + +Y F ++IVC++YF+P +E+I E L + Q+VA TF
Sbjct: 54 FPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTF 113
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ +S PE + F+T+ D+GI TI+GSA++N T + P+
Sbjct: 114 MAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLF 173
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACC 228
RD Y ++ + ++ ++D Q+ W+E +L ++Y LY +V+ +K I K + CC
Sbjct: 174 RDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCC 232
Score = 78.6 bits (185), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LG+PW
Sbjct: 360 GETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPW 418
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T I G+ V NS G+ + ++ + + L R +GIV +
Sbjct: 419 FIKTAF--INGSAPAEV--NSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLS 474
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L ELGII + +
Sbjct: 475 YLGLATLSVLYELGIIGNNKI 495
Score = 37.9 bits (84), Expect = 0.50
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX--- 147
V + E L+IP V T ++ TS P+ +V+ + DM + IVGS +F+
Sbjct: 356 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCLG 415
Query: 148 --XXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
P ++ R +T + +NIS++ F+ W LGI+ +L
Sbjct: 416 IPWFIKTAFINGSAPAEVNSRGLT--YITISLNISIIFLFLAVHFNGWKLDRKLGIVCLL 473
Query: 206 YFV 208
++
Sbjct: 474 SYL 476
Score = 35.1 bits (77), Expect = 3.5
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA---NSLAILFALGLPWLI 338
+ + V G TF+A G PE + F+ +G IG+S LG+ N L I A GL L
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL--LS 161
Query: 339 RTVS 342
TVS
Sbjct: 162 NTVS 165
>UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 639
Score = 133 bits (322), Expect = 7e-30
Identities = 60/181 (33%), Positives = 104/181 (57%)
Query: 54 IFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVA 113
IFT ++ R GA +++ +Y F LAI+C++YF +E +C+ L+IP +VA ATFM+
Sbjct: 39 IFTLQERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAG 98
Query: 114 TSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVL 173
+S P F+ + S F+ E D+G+GTI+GS++FN I++ P+ RD
Sbjct: 99 SSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSC 158
Query: 174 IYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNG 233
+Y+VN+ L+ + D I ++EA++ +LY Y ++M + + + + CC N G
Sbjct: 159 VYVVNLVGLLIVIHDNVIHFYEALIFPVLYTGYILIMVFNTRLENAFESAFETCCDINKG 218
Query: 234 V 234
+
Sbjct: 219 M 219
Score = 81.8 bits (193), Expect = 3e-14
Identities = 43/132 (32%), Positives = 72/132 (54%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF IPE +MG+T LA G +P+ S I+++ G G + ++N +G+N +L LGLPW
Sbjct: 475 GETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDVL-CLGLPW 533
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ T ++ N+ VLI+S I + + + + L R +G++L I
Sbjct: 534 LLATTAVH----PNSVVLIHSGHIVYVSMCLFGTVLTIVSAIHLNGWRLDRRLGVILFIA 589
Query: 397 YVVFIVFAILVE 408
Y F+ A+++E
Sbjct: 590 YAFFLTSAVILE 601
Score = 35.9 bits (79), Expect = 2.0
Identities = 18/49 (36%), Positives = 24/49 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILF 330
IP V G TF+A G +P GEG IG+ +G++ ILF
Sbjct: 85 IPTDVAGATFMAAGSSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILF 133
>UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1
(Na(+)/K(+)/Ca(2+)-exchange protein 1); n=12;
Euarchontoglires|Rep: Sodium/potassium/calcium exchanger
1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) - Homo sapiens
(Human)
Length = 1099
Score = 133 bits (321), Expect = 1e-29
Identities = 73/221 (33%), Positives = 125/221 (56%), Gaps = 3/221 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 440 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 499
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 500 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 559
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++ +L+ F D I W+E+++L + Y Y F + +N + +++
Sbjct: 560 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPV 619
Query: 229 KKNNGV--TASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMT 267
K + + D ++V+E DNK PS +T G++ T
Sbjct: 620 AKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
Score = 63.3 bits (147), Expect = 1e-08
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 963 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1022
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ I G + V ++S G+ + K+ + + +G + +L
Sbjct: 1023 LLFSL---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1077
Query: 397 YVVFIVFAILVELGII 412
Y VF++ ++++E II
Sbjct: 1078 YFVFLIISVMLEDRII 1093
Score = 35.1 bits (77), Expect = 3.5
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 34.3 bits (75), Expect = 6.1
Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023
Query: 156 XXXTPIAIDMRPVTRDVLI-YMVNISVLVAFVWD--GQIDWFEAMVLGI-LYILYFVVMF 211
+ PV+ + L +V + +++ FV W +LG +++LYFV +
Sbjct: 1024 LFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLI 1083
Query: 212 NSM 214
S+
Sbjct: 1084 ISV 1086
>UniRef50_Q9QZM6-4 Cluster: Isoform 4 of Q9QZM6 ; n=3;
Euteleostomi|Rep: Isoform 4 of Q9QZM6 - Rattus
norvegicus (Rat)
Length = 1153
Score = 132 bits (320), Expect = 1e-29
Identities = 73/219 (33%), Positives = 122/219 (55%), Gaps = 3/219 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E RQG +L++ Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 407 YPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 466
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 467 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 526
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++S+L+ F D I W+E+++L + Y LY F + +N + +++
Sbjct: 527 RDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVKEQLSRRPV 586
Query: 229 KK--NNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTT 265
K G + +D + E DNK PS +T G++
Sbjct: 587 AKVMALGDLSKPSDGAIEENEQQDNKKLKLPSVLTRGSS 625
Score = 63.7 bits (148), Expect = 9e-09
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 1017 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1076
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ +Q + ++S G+ + K+ + + +G + +L
Sbjct: 1077 LLFSLINALQ-----PIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLL 1131
Query: 397 YVVFIVFAILVELGII 412
Y VF+V ++++E II
Sbjct: 1132 YFVFLVISVMLEDRII 1147
Score = 35.5 bits (78), Expect = 2.7
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 1018 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1077
Query: 156 XXXTPIAIDMRPVTRDVL---IYMVNISVLVAFVWDGQIDWFEAMVLGI-LYILYFVVMF 211
A+ PV+ + L I ++ + +L W +LG +++LYFV +
Sbjct: 1078 LFSLINALQPIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLV 1137
Query: 212 NSM 214
S+
Sbjct: 1138 ISV 1140
Score = 35.1 bits (77), Expect = 3.5
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 508
>UniRef50_Q9QZM6 Cluster: Sodium/potassium/calcium exchanger 1
(Na(+)/K(+)/Ca(2+)-exchange protein 1); n=13;
Fungi/Metazoa group|Rep: Sodium/potassium/calcium
exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) -
Rattus norvegicus (Rat)
Length = 1181
Score = 132 bits (320), Expect = 1e-29
Identities = 73/219 (33%), Positives = 122/219 (55%), Gaps = 3/219 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E RQG +L++ Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 407 YPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 466
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 467 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 526
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++S+L+ F D I W+E+++L + Y LY F + +N + +++
Sbjct: 527 RDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVKEQLSRRPV 586
Query: 229 KK--NNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTT 265
K G + +D + E DNK PS +T G++
Sbjct: 587 AKVMALGDLSKPSDGAIEENEQQDNKKLKLPSVLTRGSS 625
Score = 63.7 bits (148), Expect = 9e-09
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 1045 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1104
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ +Q + ++S G+ + K+ + + +G + +L
Sbjct: 1105 LLFSLINALQ-----PIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLL 1159
Query: 397 YVVFIVFAILVELGII 412
Y VF+V ++++E II
Sbjct: 1160 YFVFLVISVMLEDRII 1175
Score = 35.5 bits (78), Expect = 2.7
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 1046 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1105
Query: 156 XXXTPIAIDMRPVTRDVL---IYMVNISVLVAFVWDGQIDWFEAMVLGI-LYILYFVVMF 211
A+ PV+ + L I ++ + +L W +LG +++LYFV +
Sbjct: 1106 LFSLINALQPIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLV 1165
Query: 212 NSM 214
S+
Sbjct: 1166 ISV 1168
Score = 35.1 bits (77), Expect = 3.5
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 508
>UniRef50_UPI0000D8CB4A Cluster: Sodium/potassium/calcium exchanger
3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
(Solute carrier family 24 member 3).; n=1; Danio
rerio|Rep: Sodium/potassium/calcium exchanger 3
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
(Solute carrier family 24 member 3). - Danio rerio
Length = 419
Score = 131 bits (317), Expect = 3e-29
Identities = 60/178 (33%), Positives = 105/178 (58%), Gaps = 5/178 (2%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
+Y F LA+VC+DYF+P +E ICE L + ++VA ATFM+ +S PE F +VI F+T+ D
Sbjct: 1 MYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 60
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+G+GTIVGSA+FN + + + RD Y + ++ L+ F++D ++
Sbjct: 61 VGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVT 120
Query: 193 WFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGID 250
W+E+++L +LY++Y ++M + + I++ KKN + +N +++G D
Sbjct: 121 WWESLILIVLYLVYILIMKFNSRVVHFIER-----RKKNPANLGNGTASNTDIDDGCD 173
Score = 89.0 bits (211), Expect = 2e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + +SN++G+N IL LGLPW
Sbjct: 278 GYTMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPW 337
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+++ + + +NS G+ F + + + + L + +G ++
Sbjct: 338 ALQTLAINY----GSTIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLM 393
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+IL+E I
Sbjct: 394 YAVFLCFSILIEFNI 408
>UniRef50_UPI000065CB15 Cluster: Sodium/potassium/calcium exchanger
5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
(Solute carrier family 24 member 5).; n=1; Takifugu
rubripes|Rep: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
(Solute carrier family 24 member 5). - Takifugu rubripes
Length = 473
Score = 131 bits (316), Expect = 4e-29
Identities = 57/179 (31%), Positives = 104/179 (58%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FPDG FT ++ + G ++Y + Y ++IVC+DYF+P +E+I E L + Q+VA ATF
Sbjct: 10 FPDGFFTVQERKDGGLVIYFLIIFYMLLAVSIVCDDYFLPSLEVISERLGLSQDVAGATF 69
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ +S PE + F+T+ D+G+ TIVGSA++N + P+
Sbjct: 70 MAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGLLTTVAGRLTCWPLF 129
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACC 228
RD L Y ++++ ++A ++D ++ W++A L ++Y++Y VV+ ++ + + + CC
Sbjct: 130 RDCLAYGISVTAVIAIIYDNKVYWYDAASLLLVYMVYIVVLCFDLRISEFVLRRVSPCC 188
Score = 86.2 bits (204), Expect = 1e-15
Identities = 47/136 (34%), Positives = 76/136 (55%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R G+ + +SN +G+N +L LGLPW
Sbjct: 342 GETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDML-CLGLPW 400
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T ++ N V +NS+G+ F ++ + I + L +GIV I
Sbjct: 401 FIKTAFVD----TNNPVEVNSSGLVFISSTLLLSIVFLFVAIHINGWKLDWKLGIVCLIC 456
Query: 397 YVVFIVFAILVELGII 412
Y++F +IL ELGII
Sbjct: 457 YILFATLSILYELGII 472
Score = 37.1 bits (82), Expect = 0.87
Identities = 19/55 (34%), Positives = 30/55 (54%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V ++ E L IP V T ++ TS P+ +V+ +SDM + IVGS +F+
Sbjct: 338 VTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFD 392
>UniRef50_Q91WD8 Cluster: Solute carrier family 24
(Sodium/potassium/calcium exchanger), member 1; n=2;
Eutheria|Rep: Solute carrier family 24
(Sodium/potassium/calcium exchanger), member 1 - Mus
musculus (Mouse)
Length = 1130
Score = 130 bits (315), Expect = 5e-29
Identities = 72/219 (32%), Positives = 123/219 (56%), Gaps = 3/219 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E RQG +L++ +Y F LAIVC++YF+P + +I L+I ++VA ATF
Sbjct: 407 YPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGATF 466
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 467 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 526
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++S+L+ F D I W+E+++L + Y LY F + +N + +++
Sbjct: 527 RDVSFYILDLSMLIVFFLDSFIAWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPV 586
Query: 229 KK--NNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTT 265
K G + +++ V E D+K PS +T G++
Sbjct: 587 AKVMALGDLSKPSEDAVEENEQQDSKKLKLPSVLTRGSS 625
Score = 64.1 bits (149), Expect = 7e-09
Identities = 38/136 (27%), Positives = 71/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 994 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1053
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ +Q V ++S G+ + K+ + + +G + +L
Sbjct: 1054 LLFSLINALQ-----PVPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLL 1108
Query: 397 YVVFIVFAILVELGII 412
Y VF+V ++++E II
Sbjct: 1109 YFVFLVISVMLEDRII 1124
Score = 36.7 bits (81), Expect = 1.1
Identities = 19/56 (33%), Positives = 26/56 (46%)
Query: 278 HTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
H I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 453 HKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 508
Score = 35.5 bits (78), Expect = 2.7
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 995 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1054
Query: 156 XXXTPIAIDMRPVTRDVL---IYMVNISVLVAFVWDGQIDWFEAMVLGI-LYILYFVVMF 211
A+ PV+ + L I ++ + +L W +LG +++LYFV +
Sbjct: 1055 LFSLINALQPVPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLV 1114
Query: 212 NSM 214
S+
Sbjct: 1115 ISV 1117
>UniRef50_Q14BI1 Cluster: Slc24a2 protein; n=7; Euteleostomi|Rep:
Slc24a2 protein - Mus musculus (Mouse)
Length = 711
Score = 130 bits (313), Expect = 9e-29
Identities = 66/164 (40%), Positives = 99/164 (60%), Gaps = 1/164 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I +VA ATF
Sbjct: 121 YPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATF 180
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F+ S++GIGTIVGSA+FN + + P+
Sbjct: 181 MAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLF 240
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 241 RDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKFN 284
Score = 67.7 bits (158), Expect = 5e-10
Identities = 38/132 (28%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 575 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 634
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ T+ + V ++S G+ + + + K+ + + +G ++ L
Sbjct: 635 LLYTIIHRF-----SPVTVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 689
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 690 YFVFLVVSVLLE 701
Score = 34.7 bits (76), Expect = 4.6
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 171 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 223
>UniRef50_Q9UI40 Cluster: Sodium/potassium/calcium exchanger 2
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2); n=34;
Euteleostomi|Rep: Sodium/potassium/calcium exchanger 2
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) - Homo
sapiens (Human)
Length = 661
Score = 130 bits (313), Expect = 9e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 1e-10
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 4.6
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
>UniRef50_A0T1T6 Cluster: NCKX1; n=2; Euteleostomi|Rep: NCKX1 -
Morone saxatilis (Striped bass)
Length = 749
Score = 129 bits (312), Expect = 1e-28
Identities = 65/165 (39%), Positives = 103/165 (62%), Gaps = 1/165 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P+ +F+ EQ +QG +L+V+ IY F LAIVC+++F+P +E+I L+I +VA ATF
Sbjct: 141 YPEDLFSVEQRQQGWVVLHVIGMIYMFVALAIVCDEFFVPGLEVITNKLQISDDVAGATF 200
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 201 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAIFSREMLHLTWWPLF 260
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FNS 213
RDV Y++++ +L+ F D I W+E+++L + YI Y M FNS
Sbjct: 261 RDVSFYILDLIMLIVFFLDNTILWWESILLVLGYISYVSFMKFNS 305
Score = 67.3 bits (157), Expect = 7e-10
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 613 GETVGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITIGLPVPW 672
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI T+ + E AV +S G+ I + ++ + R +G+ + L
Sbjct: 673 LIYTL---LHNGEPVAV--SSNGLFCAIVLLFLMLLFVIISIAACRWKMSRMLGLTMFAL 727
Query: 397 YVVFIVFAILVE 408
Y VF+V ++++E
Sbjct: 728 YFVFLVLSVMLE 739
Score = 34.7 bits (76), Expect = 4.6
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 191 ISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGM 243
>UniRef50_Q8T8P0 Cluster: Testis potassium dependent sodium/calcium
exchanger; n=2; Eumetazoa|Rep: Testis potassium
dependent sodium/calcium exchanger - Strongylocentrotus
purpuratus (Purple sea urchin)
Length = 652
Score = 129 bits (312), Expect = 1e-28
Identities = 56/145 (38%), Positives = 89/145 (61%), Gaps = 1/145 (0%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+ Y +F I F +AI+C+D+F+P +E+I E L + ++VA ATFM+ +S PE F VI
Sbjct: 115 IFYAIFVIILFIAIAIICDDFFVPSLEVISETLSLSEDVAGATFMAAGSSAPELFTAVIG 174
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
ESD+G+GTIVGSA+FN + +D RP+ RD Y +++ + F
Sbjct: 175 VAF-ESDVGVGTIVGSAVFNILIIIALTAALAGQVLNLDWRPLARDSFFYGLSLVCFIVF 233
Query: 186 VWDGQIDWFEAMVLGILYILYFVVM 210
WD + W+E+++L ILY++Y ++M
Sbjct: 234 SWDTEFTWWESLILVILYVIYLILM 258
Score = 62.9 bits (146), Expect = 2e-08
Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 16/148 (10%)
Query: 275 KNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
K G I + MG+ +A G +P+A S +++R G G + VSNA+G+N I +GL
Sbjct: 502 KIGCILNISDYTMGLVIVAVGTSVPDALSSILVARDGYGDMAVSNAIGSNVFDINLGIGL 561
Query: 335 PWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXX---XXXXXXWIVLFIGKFT------- 384
P+LIR + I G N A+L + + F +I+L I FT
Sbjct: 562 PYLIR---IAINGGTNIALLNPADQLRFDDGAFGPIPPHAKFGFILLLILLFTIFAFTAV 618
Query: 385 ---LRRTVGIVLGILYVVFIVFAILVEL 409
L +G+ I+YV+F+V+A + E+
Sbjct: 619 RFRLNAVIGVSFAIMYVLFMVYAFVQEI 646
>UniRef50_Q9QZM6-3 Cluster: Isoform 3 of Q9QZM6 ; n=3; Rattus
norvegicus|Rep: Isoform 3 of Q9QZM6 - Rattus norvegicus
(Rat)
Length = 1086
Score = 129 bits (311), Expect = 2e-28
Identities = 61/161 (37%), Positives = 98/161 (60%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E RQG +L++ Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 407 YPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 466
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 467 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 526
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
RDV Y++++S+L+ F D I W+E+++L + Y LY M
Sbjct: 527 RDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTM 567
Score = 63.7 bits (148), Expect = 9e-09
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 950 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1009
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ +Q + ++S G+ + K+ + + +G + +L
Sbjct: 1010 LLFSLINALQ-----PIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLL 1064
Query: 397 YVVFIVFAILVELGII 412
Y VF+V ++++E II
Sbjct: 1065 YFVFLVISVMLEDRII 1080
Score = 35.5 bits (78), Expect = 2.7
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 951 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1010
Query: 156 XXXTPIAIDMRPVTRDVL---IYMVNISVLVAFVWDGQIDWFEAMVLGI-LYILYFVVMF 211
A+ PV+ + L I ++ + +L W +LG +++LYFV +
Sbjct: 1011 LFSLINALQPIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKILGFTMFLLYFVFLV 1070
Query: 212 NSM 214
S+
Sbjct: 1071 ISV 1073
Score = 35.1 bits (77), Expect = 3.5
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 457 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 508
>UniRef50_Q4RPD9 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF15008, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 557
Score = 127 bits (307), Expect = 5e-28
Identities = 57/141 (40%), Positives = 92/141 (65%), Gaps = 1/141 (0%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
IY F LA+VC+ YF+P +E + E+L + Q+VA ATFM+ +S PE F ++I F+TE D
Sbjct: 2 IYMFLALAVVCDVYFVPSLEKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEGD 61
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+G+GTIVGSA+FN PI++ P+ RD + Y+++I VL+ ++D ++
Sbjct: 62 VGVGTIVGSAVFNILVIIGICGIFAGQPISLSWWPLFRDAVFYILSILVLILVIYDEKVM 121
Query: 193 WFEAMVLGILYILYFVVM-FN 212
W+E ++L +Y +Y ++M FN
Sbjct: 122 WWETIILISMYGIYIIIMKFN 142
Score = 68.5 bits (160), Expect = 3e-10
Identities = 33/82 (40%), Positives = 52/82 (63%), Gaps = 4/82 (4%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
T IPE +MG+TFLA G +P+ + I++R+G G + VSN++G+N +L LG PW +
Sbjct: 379 TLGIPEVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDVLLGLGFPWAL 438
Query: 339 RTVSLEIQGAENTAVLINSAGI 360
RT+ + + + V INS G+
Sbjct: 439 RTLIV----SYGSVVTINSKGL 456
Score = 34.3 bits (75), Expect = 6.1
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + + V G TF+A G PE + I EG +GV +G+ IL +G
Sbjct: 21 EKLSENLHLSQDVAGATFMAAGSSAPELFTSLIGVFITEGDVGVGTIVGSAVFNILVIIG 80
Query: 334 L 334
+
Sbjct: 81 I 81
Score = 34.3 bits (75), Expect = 6.1
Identities = 19/71 (26%), Positives = 34/71 (47%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL + + + V +I L IP+ + TF++ TS P+ ++I DM
Sbjct: 357 TSTLWIALFSYLMVWMVTIISFTLGIPEVIMGITFLAAGTSVPDCMASLIVARQGMGDMA 416
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 417 VSNSIGSNIFD 427
>UniRef50_Q68Y54 Cluster: Na+/Ca2+ exchanger; n=1; Asterias
amurensis|Rep: Na+/Ca2+ exchanger - Asterias amurensis
(Starfish)
Length = 616
Score = 126 bits (305), Expect = 8e-28
Identities = 63/171 (36%), Positives = 102/171 (59%), Gaps = 4/171 (2%)
Query: 43 TGDSIDSFPDGIFTDEQLRQ--GAFL-LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLK 99
TGD+ + D T ++ G F+ +Y++ F LAI+C+D+F+P +E I E L+
Sbjct: 75 TGDTNATVVDSCTTLYEVNHVPGLFVTIYIILIFVLFISLAIICDDFFVPSLEAISERLE 134
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ ++VA ATFM+ +S PE F+++I ESD+G+GTIVG+A+FN
Sbjct: 135 LSEDVAGATFMAAGSSAPELFISIIGVS-KESDVGVGTIVGTAVFNILIIIALTAALAGQ 193
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ +D RP+ RD + Y ++I + F WDG I+ +EA++L LY+ Y V+M
Sbjct: 194 VLKLDWRPLVRDCISYGISIICFIIFAWDGVIEIYEAIILLGLYVAYIVLM 244
Score = 65.7 bits (153), Expect = 2e-09
Identities = 46/143 (32%), Positives = 72/143 (50%), Gaps = 8/143 (5%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
E+ G I MG+ F+A G +P+A S +++R G G + VSNA+G+N I LG
Sbjct: 467 ERAGCILNIDHYFMGLVFVAVGTSVPDALSSILVARDGFGDMAVSNAIGSNVFDINLGLG 526
Query: 334 LPWLIRTV--SLEIQGAENTAVLINSAGI-----DFXXXXXXXXXXXXWIVLFIG-KFTL 385
LP+ IR + S I T ++ ++G +++F G +F L
Sbjct: 527 LPFFIRILITSSPINLLSETDEMMLASGALLMAPHAKFGFILLAILFFTLIVFCGVRFQL 586
Query: 386 RRTVGIVLGILYVVFIVFAILVE 408
+ VG+ +LYV FIV+A+L E
Sbjct: 587 NKFVGVSFVMLYVAFIVYALLQE 609
>UniRef50_O62805 Cluster: Retinal rod Na/Ca+K exchanger; n=3;
Euteleostomi|Rep: Retinal rod Na/Ca+K exchanger -
Tursiops truncatus (Atlantic bottle-nosed dolphin)
Length = 1014
Score = 126 bits (303), Expect = 1e-27
Identities = 58/161 (36%), Positives = 99/161 (61%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ ++ RQG +L++ +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 436 YPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 495
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 496 MAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 555
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
RD+ Y++++ +L+ F D I W+E+++L + Y LY M
Sbjct: 556 RDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTM 596
Score = 64.5 bits (150), Expect = 5e-09
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 878 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 937
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++ + I G + V ++S G+ + + K+ + + +G + +L
Sbjct: 938 MLFSF---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIALCKWRMNKILGFTMFLL 992
Query: 397 YVVFIVFAILVELGII 412
Y VF++ ++++E II
Sbjct: 993 YFVFLIISVMLEDRII 1008
Score = 35.1 bits (77), Expect = 3.5
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 486 ISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIG 537
>UniRef50_O62306 Cluster: Na/Ca,K-exchanger; n=4;
Caenorhabditis|Rep: Na/Ca,K-exchanger - Caenorhabditis
elegans
Length = 596
Score = 125 bits (301), Expect = 3e-27
Identities = 65/164 (39%), Positives = 100/164 (60%), Gaps = 1/164 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP F+ EQ + G +L++ IY F LAIVC+++F+P ++++ E L + +VA ATF
Sbjct: 87 FPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVLTEKLSLSDDVAGATF 146
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PEFF +VI F+ ++++GIGTIVGSA FN + + + P+
Sbjct: 147 MAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSKSILDLTWWPLF 206
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
RDV IYM+ +++LV F D I + EA+ + +YI+Y VM FN
Sbjct: 207 RDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVYCTVMKFN 250
Score = 67.7 bits (158), Expect = 5e-10
Identities = 35/134 (26%), Positives = 70/134 (52%), Gaps = 2/134 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF IP ++G+T LA G +P+ + I++R+G G + VS+++G+N + L +PW
Sbjct: 451 GETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPW 510
Query: 337 LIRTVSLEIQGAEN--TAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLG 394
L+ + I+ + + ++S G+ +F+ + + + GI++
Sbjct: 511 LLYFLIEYIKHPNEPLSPISVSSKGLLCSVGMLFIMLIVLVFAIFLSGWKMNKIFGILMI 570
Query: 395 ILYVVFIVFAILVE 408
+ YV F VF++ +E
Sbjct: 571 VSYVFFCVFSVSLE 584
>UniRef50_UPI000065E2E0 Cluster: Sodium/potassium/calcium exchanger
2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2)
(Retinal cone Na-Ca+K exchanger) (Solute carrier family
24 member 2).; n=1; Takifugu rubripes|Rep:
Sodium/potassium/calcium exchanger 2 precursor
(Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone
Na-Ca+K exchanger) (Solute carrier family 24 member 2).
- Takifugu rubripes
Length = 449
Score = 122 bits (294), Expect = 2e-26
Identities = 65/165 (39%), Positives = 96/165 (58%), Gaps = 1/165 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +FT E+ RQG +L++ +Y F LAIVC+++F+P + +I E L+I +VA ATF
Sbjct: 3 YPTDLFTIEERRQGYVVLHMFGMLYMFIALAIVCDEFFVPALTVITEKLEISDDVAGATF 62
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F +VI F++ S++GIGTIVGSA+FN + + P+
Sbjct: 63 MAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGMCALFSKEVLHLTWWPLF 122
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FNS 213
RDV Y+V + +L+ F D QI E++ L Y Y M FNS
Sbjct: 123 RDVSFYIVGLLMLIYFFLDNQITVLESVSLLSFYGCYVTFMKFNS 167
Score = 66.9 bits (156), Expect = 9e-10
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF++ E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L PW
Sbjct: 313 GETFWVTEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPW 372
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ + + Q V ++S G+ + + K+ + + +G + +L
Sbjct: 373 LLFNIINDFQ-----PVGVSSNGLFCAIVLLFLMLLFVIMSIAACKWKMSKILGSTMFLL 427
Query: 397 YVVFIVFAILVELGII 412
Y VF+V ++++E II
Sbjct: 428 YFVFLVVSVMLEDKII 443
Score = 34.3 bits (75), Expect = 6.1
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 53 ISDDVAGATFMAAGGSAPELFTSVIGVFVSHSNVGIGTIVGSAVFNILFVIGM 105
>UniRef50_UPI00015B61EF Cluster: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger, putative;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger, putative -
Nasonia vitripennis
Length = 692
Score = 121 bits (291), Expect = 4e-26
Identities = 59/169 (34%), Positives = 96/169 (56%), Gaps = 1/169 (0%)
Query: 46 SIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVA 105
+I+ FP + + G +++V+ IYTF LAIVC+DYF+ ++ ICE+LK+ +VA
Sbjct: 160 AIEQFPRPLMGPYARKHGGLVIHVLVAIYTFLGLAIVCDDYFVASLDRICEELKLSPDVA 219
Query: 106 AATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDM 165
ATFM+ +S PE VI F + D+G+ ++GSA+FN T ++
Sbjct: 220 GATFMAAGSSAPELATVVIGVFFAKDDIGVSGVIGSAVFNIMFVISVCGLCSSTVSKLNW 279
Query: 166 RPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FNS 213
P+ RD Y ++I V++ + + I W EA+ + I+Y +Y V + FNS
Sbjct: 280 WPLCRDCFFYFISILVMLGTIANESISWGEALFMLIMYGVYCVALAFNS 328
Score = 88.6 bits (210), Expect = 3e-16
Identities = 49/140 (35%), Positives = 73/140 (52%), Gaps = 4/140 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+TF+A G +P+A S + + G G + VSNA+G+N IL LGLPW
Sbjct: 549 GSTLGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGLGDMAVSNAVGSNVFDILVCLGLPW 608
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T ++ + V + S G+ + + + L R G+VL I
Sbjct: 609 FIQTAMIQ----PGSHVNVTSRGLTYSTLSLLSTVVFLVVATHFNGWKLDRRYGVVLMIW 664
Query: 397 YVVFIVFAILVELGIIFDRN 416
Y++FIV A L EL + N
Sbjct: 665 YLIFIVLASLYELNVFGQMN 684
>UniRef50_O62088 Cluster: Putative uncharacterized protein ncx-5;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein ncx-5 - Caenorhabditis elegans
Length = 591
Score = 121 bits (291), Expect = 4e-26
Identities = 61/176 (34%), Positives = 101/176 (57%), Gaps = 2/176 (1%)
Query: 38 EVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICED 97
E+ + +S FP IF+ + R+G ++++ IY F LA+VC+++F+P + +I E
Sbjct: 8 EIFSSNANS-SQFPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEV 66
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L I +VA ATFM+ S PEFF ++ F+ + ++G+GTIVGSA FN
Sbjct: 67 LAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFS 126
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFN 212
+ + P+ RD+ Y +++ +L+ F D I+W EA+V+ +YI Y F + FN
Sbjct: 127 RQVLHLTWWPLFRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFN 182
Score = 65.7 bits (153), Expect = 2e-09
Identities = 35/134 (26%), Positives = 64/134 (47%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G TF IP +MG+T LA G +P+ + I++R+G G + VS+++G+N + L +PW
Sbjct: 448 GETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDVCVGLPIPW 507
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
LI + + + S G+ + I ++ + + G+++
Sbjct: 508 LIHFAIGVFKSEPTQNISVTSNGLVCSLGLLFAMLIVLLTCVAISRWKMDKFFGLLMIFS 567
Query: 397 YVVFIVFAILVELG 410
Y F + IL+E G
Sbjct: 568 YCGFCMLCILLETG 581
>UniRef50_Q4SLY4 Cluster: Chromosome 13 SCAF14555, whole genome
shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 13
SCAF14555, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 647
Score = 120 bits (288), Expect = 1e-25
Identities = 59/164 (35%), Positives = 98/164 (59%), Gaps = 1/164 (0%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P+ +F+ + R+G +L+++ +Y F LAIVC+++F+P + +I L I +VA ATF
Sbjct: 133 YPEDLFSIKDRRRGWVVLHIIGMMYMFIALAIVCDEFFVPALGVITHKLAISDDVAGATF 192
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F+ S++GIGTIVGSA+FN + + P+
Sbjct: 193 MAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREVLHLTWWPLF 252
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
RDV Y++++ +L+ F D I W+E+M+L Y +Y + M FN
Sbjct: 253 RDVSFYILDLVMLIVFFLDNVIMWWESMMLVGGYTVYVIFMKFN 296
Score = 63.3 bits (147), Expect = 1e-08
Identities = 38/136 (27%), Positives = 70/136 (51%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 511 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGMGDMAVSSSVGSNIFDITVGLPVPW 570
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ + I G V ++S G+ I + + + + +G + +L
Sbjct: 571 LMYSA---IHGL--APVAVSSNGLFCAIVLLFIMLLFVIISIASCNWKMNKALGSTMFLL 625
Query: 397 YVVFIVFAILVELGII 412
Y +F+V ++++E II
Sbjct: 626 YFIFLVLSVMLEDRII 641
Score = 36.7 bits (81), Expect = 1.1
Identities = 18/57 (31%), Positives = 27/57 (47%)
Query: 278 HTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
H I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 179 HKLAISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 235
Score = 33.9 bits (74), Expect = 8.1
Identities = 26/126 (20%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 512 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGMGDMAVSSSVGSNIFDITVGLPVPWL 571
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ +W LG +++LYF+
Sbjct: 572 MYSAIHGLAPVAVSSNGLFCAIVLLFIMLLFVIISI---ASCNWKMNKALGSTMFLLYFI 628
Query: 209 VMFNSM 214
+ S+
Sbjct: 629 FLVLSV 634
>UniRef50_Q8C261 Cluster: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5); n=7;
Murinae|Rep: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) - Mus
musculus (Mouse)
Length = 501
Score = 120 bits (288), Expect = 1e-25
Identities = 56/188 (29%), Positives = 100/188 (53%), Gaps = 1/188 (0%)
Query: 41 CATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKI 100
CA + + FP+G FT ++ G ++Y + +Y ++IVC+ YF+P +E+I + L +
Sbjct: 46 CAVSPASE-FPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGL 104
Query: 101 PQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTP 160
Q+VA ATFM+ +S PE + F+T+ D+GI TI+GSA++N
Sbjct: 105 SQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMV 164
Query: 161 IAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLI 220
+ P+ RD +Y V++ + ++D +I W+E L ++Y LY +++ +
Sbjct: 165 STLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHV 224
Query: 221 DKIWAACC 228
K + CC
Sbjct: 225 MKTCSPCC 232
Score = 81.4 bits (192), Expect = 4e-14
Identities = 41/141 (29%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LGLPW
Sbjct: 361 GETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDML-CLGLPW 419
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T + + +NS G+ + ++ + + L R +G+V +L
Sbjct: 420 FIKTAFTN----ASAPIEVNSKGLTYITISLNISILFLFLAVHFNGWKLDRKLGVVCLVL 475
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L E+GII + +
Sbjct: 476 YLGLATLSVLYEIGIIGNNRI 496
Score = 38.3 bits (85), Expect = 0.38
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX-----XXX 150
E L IP V T ++ TS P+ +V+ + DM I IVGS +F+
Sbjct: 362 ETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDMLCLGLPWFI 421
Query: 151 XXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFV 208
PI ++ + +T + +NIS+L F+ W LG++ ++ ++
Sbjct: 422 KTAFTNASAPIEVNSKGLT--YITISLNISILFLFLAVHFNGWKLDRKLGVVCLVLYL 477
Score = 34.3 bits (75), Expect = 6.1
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA---NSLAILFALGL 334
+ + V G TF+A G PE + F+ +G IG+S LG+ N L I A GL
Sbjct: 104 LSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL 159
>UniRef50_Q01A52 Cluster: K-independent Na+/Ca2+ exchanger JSX; n=2;
Ostreococcus|Rep: K-independent Na+/Ca2+ exchanger JSX -
Ostreococcus tauri
Length = 443
Score = 119 bits (287), Expect = 1e-25
Identities = 57/155 (36%), Positives = 92/155 (59%), Gaps = 2/155 (1%)
Query: 58 EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCP 117
E +R G ++LYVV +Y F +AIVC+DYF+ +E IC+ L + ++VA ATFM+ +S P
Sbjct: 32 EWIRNGGWVLYVVGILYMFLGIAIVCDDYFVSSLEKICDKLGLSEDVAGATFMAAGSSAP 91
Query: 118 EFFVNVISTFLTE--SDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIY 175
E F + +S + +++GI IVGSA+FN + +D RPVTRD + Y
Sbjct: 92 ELFSSGMSLISPDATNEIGISAIVGSAVFNMLFIVGATVLCAGCSLDLDWRPVTRDCMFY 151
Query: 176 MVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ + ++ +DG+I W+E ++ +LY Y + M
Sbjct: 152 AMAVLTVLLIFYDGRITWYEGLICVLLYATYVLCM 186
Score = 67.3 bits (157), Expect = 7e-10
Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IPE VMG +A G +P+A +++ GEG + V+NA+G+N I LGLPWLI
Sbjct: 313 IPEVVMGTLVVAAGTSIPDALGSIAVAKAGEGDMAVANAVGSNIFDIWLGLGLPWLIILP 372
Query: 342 SLEIQGAE-NTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVF 400
+ + T+ LI S I F +++LF ++ L R+ GIV YVVF
Sbjct: 373 TKPGRMISIQTSQLIPSMSILF------GVLLLYYLMLFFNRWQLTRSAGIVFMCTYVVF 426
Query: 401 IVFAI 405
+ I
Sbjct: 427 ACYCI 431
>UniRef50_A7S4I7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 643
Score = 118 bits (285), Expect = 2e-25
Identities = 60/170 (35%), Positives = 98/170 (57%), Gaps = 2/170 (1%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T + +P+ FT EQ +QGA + +++ Y F LAI C+++F+P + +I E L++ +
Sbjct: 86 TSERSAEYPEDEFTLEQKQQGAVICHIIGMCYMFLALAIACDEFFVPSLTVIIEKLELKE 145
Query: 103 NVAAATFMSVATSCPEFFVNVISTFL-TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F + I TF+ +S++GIGTIVGSA+FN +
Sbjct: 146 DVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVL 205
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQ-IDWFEAMVLGILYILYFVVM 210
+ P+ RD + Y + + +L+ F G I W+E++VL + Y Y + M
Sbjct: 206 ELTWWPLFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYVIFM 255
Score = 77.4 bits (182), Expect = 7e-13
Identities = 43/137 (31%), Positives = 77/137 (56%), Gaps = 7/137 (5%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+TF IP VMG+TFLA G +P+ + +++R+G G + VS+++G+N I L LPW
Sbjct: 513 GYTFDIPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPW 572
Query: 337 L-IRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGI 395
L V+L + AV ++S GI + + + ++ + +++G + +
Sbjct: 573 LCYSAVNLGL------AVNVSSRGILYSVIMLFCMLIAVVVSIAASRWRMSKSLGACMFV 626
Query: 396 LYVVFIVFAILVELGII 412
Y++F+V A+L+ LG I
Sbjct: 627 FYIIFLVLAVLLALGKI 643
Score = 33.9 bits (74), Expect = 8.1
Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMS-RRGEGGIGVSNALGANSLAILFALGL 334
+ E V G TF+A GG PE + FI + + +G+ +G+ +LF +G+
Sbjct: 143 LKEDVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGM 196
>UniRef50_Q9VN12 Cluster: Probable sodium/potassium/calcium
exchanger CG1090 (Na(+)/K(+)/Ca(2+)- exchange protein
CG1090); n=5; Bilateria|Rep: Probable
sodium/potassium/calcium exchanger CG1090
(Na(+)/K(+)/Ca(2+)- exchange protein CG1090) -
Drosophila melanogaster (Fruit fly)
Length = 642
Score = 118 bits (283), Expect = 4e-25
Identities = 56/172 (32%), Positives = 98/172 (56%), Gaps = 1/172 (0%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +I+ FP + + G +L+++ ++TF LAIVC++YF+ ++ +CE+LK+
Sbjct: 103 TPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKLSP 162
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ +S PE VI F + D+GI ++GSA+FN T
Sbjct: 163 DVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTVCQ 222
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FNS 213
++ P+ RD Y V+I V++ +++ I FE++V+ + Y+ Y V + FN+
Sbjct: 223 LNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGYCVALHFNT 274
Score = 81.8 bits (193), Expect = 3e-14
Identities = 45/135 (33%), Positives = 72/135 (53%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+TF+A G +P+A S + + G G + VSNA+G+N IL LGLPW
Sbjct: 501 GSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPW 560
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T ++ + V + S G+ + + + + L + +GI+L +
Sbjct: 561 FIQTAIIK----PGSHVNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVW 616
Query: 397 YVVFIVFAILVELGI 411
Y+ FI A L EL +
Sbjct: 617 YLFFITLASLYELNV 631
>UniRef50_UPI00004D7884 Cluster: Sodium/potassium/calcium exchanger
3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
(Solute carrier family 24 member 3).; n=2;
Tetrapoda|Rep: Sodium/potassium/calcium exchanger 3
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3)
(Solute carrier family 24 member 3). - Xenopus
tropicalis
Length = 524
Score = 117 bits (282), Expect = 5e-25
Identities = 51/96 (53%), Positives = 73/96 (76%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FPD IF++E R GA +L+V+F +Y F LAIVC+D+F+P +E I E L++ ++VA ATF
Sbjct: 2 FPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAGATF 61
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
M+ +S PE F +VI F+T+ D+G+GTIVGSA+FN
Sbjct: 62 MAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFN 97
Score = 74.9 bits (176), Expect = 4e-12
Identities = 43/135 (31%), Positives = 72/135 (53%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 388 GFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 447
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ L+N+ V F K+ L + +G+ +L
Sbjct: 448 ALQTLAVDYGSYNVKKCLLNA---QLLLLCIWLQRMQVCGVRF-NKWRLDKKLGVACLLL 503
Query: 397 YVVFIVFAILVELGI 411
Y VF+ +IL E +
Sbjct: 504 YGVFLCLSILTEFNV 518
>UniRef50_Q17BT7 Cluster: Potassium-dependent sodium-calcium
exchanger, putative; n=1; Aedes aegypti|Rep:
Potassium-dependent sodium-calcium exchanger, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 492
Score = 117 bits (282), Expect = 5e-25
Identities = 53/115 (46%), Positives = 77/115 (66%), Gaps = 1/115 (0%)
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ ATS PE FVNVI TF+TE D+G+GTIVGSA+FN +
Sbjct: 4 DVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVP 63
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAF 217
+D P+TRD L Y + +++L+ + D +++W+EA++L +LYI+Y VM+ KAF
Sbjct: 64 LDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYIAVMYYD-KAF 117
Score = 114 bits (275), Expect = 4e-24
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 1/141 (0%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP+SVMG+TFLA G +PEA S I++++G G +G+SN++G+N+ IL LGLPW
Sbjct: 348 GDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYGSMGISNSIGSNTFDILLCLGLPW 407
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+ I+ + V INSAG+++ +I ++ KF L R VG I+
Sbjct: 408 FIKAAFSPIEKGHHW-VGINSAGLEYSAISLLSTLLMLYIAFWLNKFRLDRRVGYACLIM 466
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y VF++ A L+EL + F N+
Sbjct: 467 YAVFLILASLIELNVFFPVNL 487
Score = 38.7 bits (86), Expect = 0.28
Identities = 20/55 (36%), Positives = 29/55 (52%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ +I + LKIP +V TF++ TS PE +VI MGI +GS F+
Sbjct: 344 ITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKQGYGSMGISNSIGSNTFD 398
>UniRef50_Q00YP0 Cluster: Solute carrier family 24 member 4, isoform
1; n=2; Ostreococcus|Rep: Solute carrier family 24
member 4, isoform 1 - Ostreococcus tauri
Length = 545
Score = 110 bits (265), Expect = 6e-23
Identities = 62/216 (28%), Positives = 106/216 (49%), Gaps = 4/216 (1%)
Query: 56 TDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATS 115
T+ ++G + Y V +Y F +AIVC+D+F+ +E ICE L + +VA ATFM+ +S
Sbjct: 57 TESWEKKGGLVAYFVGVVYLFIGIAIVCDDFFVASLEKICERLGLSDDVAGATFMAAGSS 116
Query: 116 CPEFFVNVISTFLTESD--MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVL 173
PE + +S + +D +G+GTIVGSA+FN + +D RP+ RD
Sbjct: 117 APELAASAMSLINSGADNAIGVGTIVGSAVFNILVIIGATVIFAGETLKLDWRPLARDCT 176
Query: 174 IYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNG 233
Y I + G ++W+E ++ LY+LY M+ + L+D+ + K
Sbjct: 177 FYFAAIIGITLTFNGGVVNWWEGLIYVCLYMLYIAFMWKNQYFMELLDRKFGKYMKSMTD 236
Query: 234 VTASLND--NNVSVEEGIDNKGFNDPSPVTNGTTMT 267
+ + D + +VE N+P + ++T
Sbjct: 237 SASDMEDGLGDGAVEMKDQASRRNEPGDIKQQLSVT 272
Score = 51.2 bits (117), Expect = 5e-05
Identities = 25/57 (43%), Positives = 34/57 (59%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
IP VMG T LA G +P+A S ++R G + V+NA+G+N I LGLPW +
Sbjct: 415 IPPVVMGTTVLAAGTSIPDALSSISVARDGFADMAVANAVGSNVFDIWLGLGLPWTL 471
>UniRef50_A7RJP9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 209
Score = 108 bits (259), Expect = 3e-22
Identities = 50/101 (49%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Query: 46 SIDSFPDGIFTDEQL-RQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNV 104
SI FP T Q +QG + +V IYTF LA VC++YF+ +E IC+ L + +V
Sbjct: 71 SISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCDEYFVSSLERICDGLNLKSDV 130
Query: 105 AAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
A ATFM+ +S PEFF +VI F+T+ D+GIGTIVGSA+FN
Sbjct: 131 AGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFN 171
>UniRef50_UPI000069FB37 Cluster: Sodium/potassium/calcium exchanger
5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
(Solute carrier family 24 member 5).; n=2;
Tetrapoda|Rep: Sodium/potassium/calcium exchanger 5
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5)
(Solute carrier family 24 member 5). - Xenopus
tropicalis
Length = 555
Score = 106 bits (255), Expect = 9e-22
Identities = 61/192 (31%), Positives = 105/192 (54%), Gaps = 8/192 (4%)
Query: 37 HEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICE 96
+E +C S + FP+ FT+++ +QG +++ + +Y F +AIVC YFIP +E+I E
Sbjct: 3 NETLCIASPSSE-FPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISE 61
Query: 97 DLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXX 156
L + Q+VA ATFM++ +S PEF + F+T+ D+G+ TIVGSA++N
Sbjct: 62 RLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLL 121
Query: 157 XXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKA 216
+ + M V R V +M ++ WD + +E+ L ++Y +Y V M ++
Sbjct: 122 SLS--LLYMLKVWRYVCPWMYFSTI----HWDAW-NRYESASLILIYGIYIVTMCFDIRI 174
Query: 217 FVLIDKIWAACC 228
I + ++ CC
Sbjct: 175 NQYIMRRFSPCC 186
Score = 85.4 bits (202), Expect = 3e-15
Identities = 43/137 (31%), Positives = 79/137 (57%), Gaps = 6/137 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEA-CSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
G T IP++VMG+T LA G +P+ S+ + G+G + +SN +G+N +L LG+P
Sbjct: 414 GETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREAGKGDMAMSNIVGSNVFDML-CLGVP 472
Query: 336 WLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGI 395
W I+TV ++ + V +NS+GI + ++ + + + L + +G++ +
Sbjct: 473 WFIKTVFVD----RSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLL 528
Query: 396 LYVVFIVFAILVELGII 412
+Y++F+ +IL ELGII
Sbjct: 529 MYLLFVTLSILYELGII 545
>UniRef50_Q0P434 Cluster: Zgc:153443; n=10; Euteleostomi|Rep:
Zgc:153443 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 231
Score = 104 bits (249), Expect = 5e-21
Identities = 52/115 (45%), Positives = 77/115 (66%), Gaps = 4/115 (3%)
Query: 34 NVAHEVVCATGDSID----SFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIP 89
NV+ +V A S + +P+ +FT EQ RQGA +L++ +Y F LAIVC+++F+P
Sbjct: 97 NVSADVPIAMASSAEHSKGEYPEDLFTLEQRRQGAVVLHMFGMMYMFIALAIVCDEFFVP 156
Query: 90 CVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
+ +I E L+I +VA ATFM+ S PE F +VI F++ S++GIGTIVGSA+F
Sbjct: 157 ALTVITEKLEISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVF 211
>UniRef50_UPI0000E47BAC Cluster: PREDICTED: similar to cone
sodium-calcium potassium exchanger; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
cone sodium-calcium potassium exchanger -
Strongylocentrotus purpuratus
Length = 651
Score = 102 bits (244), Expect = 2e-20
Identities = 44/96 (45%), Positives = 66/96 (68%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +FT +Q + GA +L+V+ IY F LAIVC+++F+P + +I + L + +VA ATF
Sbjct: 107 YPRDLFTLQQKKDGAIVLHVILMIYMFVALAIVCDEFFVPALSVITDKLDLSDDVAGATF 166
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
M+ S PE F ++I F SD+G+GTIVGSA+FN
Sbjct: 167 MAAGGSAPELFTSLIGVFFARSDVGVGTIVGSAVFN 202
Score = 65.7 bits (153), Expect = 2e-09
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E VMG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 515 GDTIGIEERVMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 574
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++ ++S +V ++S G+ I++ + K+ + + +G + +
Sbjct: 575 ILWSIS-----QNGASVSVDSKGLFCSIFLLFGMLILVVILIAVNKWRMTKIMGGCMFLF 629
Query: 397 YVVFIVFAILVELGII 412
Y+ F+ ++L+ II
Sbjct: 630 YLAFLAISLLLLADII 645
>UniRef50_Q7PLW3 Cluster: CG12061-PA.3; n=1; Drosophila
melanogaster|Rep: CG12061-PA.3 - Drosophila melanogaster
(Fruit fly)
Length = 353
Score = 101 bits (241), Expect = 5e-20
Identities = 56/154 (36%), Positives = 81/154 (52%), Gaps = 7/154 (4%)
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATF++ +TS PE FVN + TF+T D+G+GTIVGS++FN P
Sbjct: 4 DVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFN-ILVIAGVCGIFTQPTK 62
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDK 222
+D PVTRD Y++ I+ L +WD + W+EA L +LYI Y + + + L+ +
Sbjct: 63 LDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLSFDRRIQNLVRR 122
Query: 223 IWAACCKKNNGVTASLNDNNVSVEEGIDNKGFND 256
KKN + L D + E KGF D
Sbjct: 123 ------KKNEHAESELLDEDPMTREEEPLKGFRD 150
Score = 83.0 bits (196), Expect = 1e-14
Identities = 40/133 (30%), Positives = 73/133 (54%), Gaps = 6/133 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+ IP+++MG+T LA G +PE S +I+S++G G + + NA+G+N+ IL LGLPW
Sbjct: 215 GYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPW 274
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L++ + + + I+S + ++ L +F + +TVG + I
Sbjct: 275 LLKILIYQ------QKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIF 328
Query: 397 YVVFIVFAILVEL 409
Y +F++ A +E+
Sbjct: 329 YALFLIIACTLEI 341
>UniRef50_UPI0000E48262 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 346
Score = 87.4 bits (207), Expect = 6e-16
Identities = 45/136 (33%), Positives = 75/136 (55%), Gaps = 4/136 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G P+ I +R G G + +S+++G+N IL LGLPW
Sbjct: 205 GDTIGIPDTVMGLTLLAAGASTPDTMLSIIAARGGYGDMAISHSIGSNLFDILVGLGLPW 264
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+TV ++ + V + S I + +++ + +F L +T+G+ I
Sbjct: 265 FIQTVIID----HRSTVTVYSGAISYISMLLLLTVVIAVVLINVCRFRLGKTLGVFFIIF 320
Query: 397 YVVFIVFAILVELGII 412
+V+FI+ +IL EL +I
Sbjct: 321 FVIFIMVSILFELNLI 336
>UniRef50_Q891X4 Cluster: Putative sodium/calcium exchanger protein;
n=1; Clostridium tetani|Rep: Putative sodium/calcium
exchanger protein - Clostridium tetani
Length = 347
Score = 85.0 bits (201), Expect = 3e-15
Identities = 85/322 (26%), Positives = 141/322 (43%), Gaps = 27/322 (8%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTE--SDMGIGTIVGSALFNXXXXXXXXXX 155
LKIP +V ATF ++++S PEF +I+ + + +D+G+ TI GS +FN
Sbjct: 43 LKIPTSVRGATFDAISSSFPEFSTAMIAVIVYKRFTDVGVPTIAGSGVFNILIIPMATIF 102
Query: 156 XXXTP---IAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFN 212
I +D + V RD++ Y + I LV F + G F +VL ++YI Y V++
Sbjct: 103 AYRGKDLLIKVDKKVVYRDMIFYTMAIGALVFFTYLGSYTVFAGIVLVLIYIGYIFVLYG 162
Query: 213 SMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAI 272
K + K + K + A L+ EE + +T I
Sbjct: 163 ETKNY---RKNISEENKAYEEIAAELD-----TEEDMSYLKIFIIMAITIALIWVSIDGI 214
Query: 273 DEKNG--HTFF-IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAIL 329
+ TFF IP+ ++ + +A +P+ S+ G+ V+NA+G+N I
Sbjct: 215 IQSTTVISTFFNIPQYIVSVVIIAACTSIPDTLLSIKSSQDGDVEGAVANAVGSNIFDIC 274
Query: 330 FALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTV 389
LG+P +I +L +EN VLI F +L + K + +
Sbjct: 275 ICLGVPIIIAGKTLPANFSENVGVLI------FLIVSMLTTA-----LLLLKKKGVTKKD 323
Query: 390 GIVLGILYVVFIVFAILVELGI 411
V+ +Y+VFI++ I V L I
Sbjct: 324 AFVMLAVYIVFIIYIIGVALNI 345
>UniRef50_Q7PLW2 Cluster: CG12061-PB.3; n=2; Diptera|Rep:
CG12061-PB.3 - Drosophila melanogaster (Fruit fly)
Length = 110
Score = 80.2 bits (189), Expect = 9e-14
Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L++ +VA ATF++ +TS PE FVN + TF+T D+G+GTIVGS++FN
Sbjct: 17 LRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFN-ILVIAGVCGIF 75
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQI 191
P +D PVTRD Y++ I+ L +WD +
Sbjct: 76 TQPTKLDWWPVTRDTAWYLIAIASLTYVLWDSLV 109
>UniRef50_Q0SSQ4 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=4; Firmicutes|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Clostridium
perfringens (strain SM101 / Type A)
Length = 331
Score = 79.0 bits (186), Expect = 2e-13
Identities = 68/285 (23%), Positives = 125/285 (43%), Gaps = 23/285 (8%)
Query: 70 VFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
+F I F LL I D F+ I + L +P + T +S+ TS PE V++ +
Sbjct: 4 IFLIIGFLLL-IKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISAALKG 62
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+D+ +G ++GS LFN P+ I + D ++ ++ VL F + G
Sbjct: 63 SNDITMGNVLGSNLFN--LLAALGCTAIVAPLVIKKHIIKNDFIVNLLATFVLYVFTFTG 120
Query: 190 ------QIDWFEAMVLGILYILYFVVMFNSMK-AFVLIDKIWAACCKKNNGVTASLNDNN 242
+ + +VL ++ I Y + + ++K + D++ VT D
Sbjct: 121 LIGSKNSLSRMDGLVLVLMCITYIIYLIYTVKRSHKKEDEV---------AVTVEFEDFE 171
Query: 243 VSVEEGIDNKGFNDPSPVTN--GTTMTEKPAIDEKNGHT--FFIPESVMGMTFLAFGGCL 298
+ ++ G N + G + K +D + + E ++G+T +A G L
Sbjct: 172 EKNIKSPNSTGKNILLSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSL 231
Query: 299 PEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
PE + + +++GE I + N LG+N+ IL LGL LI +++
Sbjct: 232 PELVTSLVAAKKGENDIALGNILGSNTFNILLILGLSSLISPITI 276
Score = 37.9 bits (84), Expect = 0.50
Identities = 27/122 (22%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L + + + T +++ TS PE ++++ E+D+ +G I+GS FN
Sbjct: 213 LGLSEKLVGLTIVAIGTSLPELVTSLVAAKKGENDIALGNILGSNTFN--ILLILGLSSL 270
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVW-----DGQIDWFEAMVLGILYILY--FVVM 210
+PI I ++ D++ +V ++ A ++ + + +E + L +LY+ Y +++M
Sbjct: 271 ISPITI-AASLSVDLIFLIVVTLIIGALIFLNKKKEKVLTRYEGLFLLVLYVGYTVYIIM 329
Query: 211 FN 212
N
Sbjct: 330 RN 331
Score = 37.1 bits (82), Expect = 0.87
Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+P ++G+T ++ G PE + +G I + N LG+N +L ALG ++ +
Sbjct: 33 VPAVIIGLTIVSLGTSAPELAVSISAALKGSNDITMGNVLGSNLFNLLAALGCTAIVAPL 92
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
++ +N ++ + L K +L R G+VL ++ + +I
Sbjct: 93 VIKKHIIKNDFIV--------NLLATFVLYVFTFTGLIGSKNSLSRMDGLVLVLMCITYI 144
Query: 402 VFAI 405
++ I
Sbjct: 145 IYLI 148
>UniRef50_Q8TWT1 Cluster: Ca2+/Na+ antiporter; n=1; Methanopyrus
kandleri|Rep: Ca2+/Na+ antiporter - Methanopyrus
kandleri
Length = 329
Score = 79.0 bits (186), Expect = 2e-13
Identities = 60/236 (25%), Positives = 113/236 (47%), Gaps = 20/236 (8%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ ++VA AT ++ TS PEF ++ S L ++G+GTI+GSA++N
Sbjct: 56 LSESVAGATLAAIGTSAPEFGSSLSSILLEHPNVGVGTILGSAVYNVTVIPGLAALAAG- 114
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVL 219
+ ++ RDVL Y++ + V++ +WD + EA+ LY LY ++M + ++ +
Sbjct: 115 GLTLERAVYRRDVLFYLLALVVVLVSLWDRVVLRVEALAWVALYGLYVLLMRRTDESTIG 174
Query: 220 IDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHT 279
+ G T + ++ V + G + + + + +D G
Sbjct: 175 AE-----------GDTGEASLRSLVVRVSVAVVG------IAALSDLMVRATVDFCEG-- 215
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
F + ES + + A G +P+ + +RRG G + VSNA+G+N+ +L LG+P
Sbjct: 216 FGLSESRVSLLLNAAGTSVPDTLASVHAARRGFGSLAVSNAVGSNTFDLLVCLGVP 271
>UniRef50_Q8TLL5 Cluster: Sodium/calcium exchanger protein; n=2;
Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
- Methanosarcina acetivorans
Length = 315
Score = 78.2 bits (184), Expect = 4e-13
Identities = 69/280 (24%), Positives = 124/280 (44%), Gaps = 20/280 (7%)
Query: 73 IYTFTL-LAIVC--NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
I+ F L LA++ +D+FI I IP+ + AT +S AT+ PEF V+ + +L
Sbjct: 6 IFLFLLSLAMISKGSDWFIEAAVAISNKSGIPKMLIGATIVSFATTAPEFAVSATAAYLG 65
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+D+ IG VGS + N P+ D P+ +++ I ++V+ DG
Sbjct: 66 HTDVTIGNAVGSVICNTGLVLGSIIAVKAIPMKDDTFPIKSGLMLLSGIILIIVS--RDG 123
Query: 190 QIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGI 249
++ + + IL +++F +F++ K ++ + G + D + + I
Sbjct: 124 NVNRLDGI---ILLLVFFAFLFHASKT----QRVLFGDDEPGRG-KMKIKD----IRKDI 171
Query: 250 DNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSR 309
S V + + K IPE ++ +T +A G LPE + R
Sbjct: 172 AFFVLGSLSVVIGSRILVDSGI---KIAEWIGIPEVIIALTAVAIGTSLPELVTAIASLR 228
Query: 310 RGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAE 349
+G + + N LGAN++ + LG+ IR + + Q AE
Sbjct: 229 KGHQDLSIGNILGANTMDVAMILGVSSQIRVLPVSEQLAE 268
Score = 37.9 bits (84), Expect = 0.50
Identities = 23/118 (19%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I E + IP+ + A T +++ TS PE + S D+ IG I+G+ +
Sbjct: 195 IAEWIGIPEVIIALTAVAIGTSLPELVTAIASLRKGHQDLSIGNILGANTMDVAMILGVS 254
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
P++ + ++ ++++++V + +++ +E V+ Y+ Y +F
Sbjct: 255 SQIRVLPVSEQLAEYDFP-FMFFISLALIVFGITGKKLERWEGGVILGAYLFYVAGLF 311
>UniRef50_A1ZFW8 Cluster: Putative K+-dependent Na+/Ca+
exchanger-like protein; n=1; Microscilla marina ATCC
23134|Rep: Putative K+-dependent Na+/Ca+ exchanger-like
protein - Microscilla marina ATCC 23134
Length = 389
Score = 77.8 bits (183), Expect = 5e-13
Identities = 44/147 (29%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
L +V + F ++ + + +FI ++ I E +K+P +VA AT +++ TS PE + +
Sbjct: 5 LALVVILLAFYVMTEIVDRHFIKSLDNIAEWMKLPPSVAGATLLALGTSAPEISTALFAL 64
Query: 127 FLTESD--MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVA 184
FL ++ G+GTIVGSA+F + ++ RPV RD + Y ++ +L+
Sbjct: 65 FLEGANPATGVGTIVGSAIFQILVVIGFAAVVKTS--YLNWRPVMRDSIFYAFSVGLLIL 122
Query: 185 FVWDGQIDWFEAMVLGILYILYFVVMF 211
FV D + E + Y LY V+F
Sbjct: 123 FVADNKFTLIEGIAFVCSYFLYLFVLF 149
Score = 68.9 bits (161), Expect = 2e-10
Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 5/129 (3%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP +++ +T LA G +PE S I++++G G + ++NA+G+N IL +LGLP LI +
Sbjct: 265 IPPAIIALTILAGGSSIPEMISSAIVAKQGRGDMAIANAIGSNIFDILMSLGLPVLIYIL 324
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
I+G T + A I ++LF+ KF R G+ L LY++++
Sbjct: 325 ---IKGQPLTD--LGGANITSSIILLFTTLIVVVLLLFVQKFKATRPFGLFLIFLYLIYV 379
Query: 402 VFAILVELG 410
V A + +G
Sbjct: 380 VAAYMGWIG 388
Score = 36.3 bits (80), Expect = 1.5
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 73 IYTFTLLAIVCNDYF-IPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES 131
++ +L+ I YF + E + + + IP + A T ++ +S PE + I
Sbjct: 237 VFLLSLVIIAGASYFLVVAAEALAKAMDIPPAIIALTILAGGSSIPEMISSAIVAKQGRG 296
Query: 132 DMGIGTIVGSALFN 145
DM I +GS +F+
Sbjct: 297 DMAIANAIGSNIFD 310
>UniRef50_A6GGZ5 Cluster: Ca2+/Na+ antiporter; n=1; Plesiocystis
pacifica SIR-1|Rep: Ca2+/Na+ antiporter - Plesiocystis
pacifica SIR-1
Length = 361
Score = 75.8 bits (178), Expect = 2e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
L +V + F ++ V F+ ++ I E + + +VA AT ++ TS PE +++
Sbjct: 5 LAIVTVLVAFYAMSAVVEGPFMASLDRIAERMGLSSSVAGATLLAFGTSAPELSTALVAL 64
Query: 127 FL--TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVA 184
F + G+G+IVGSA+F + +D RPV RD L Y ++I +L+A
Sbjct: 65 FAEGAHASTGVGSIVGSAIFQILVVVGFAAVVRAS--TLDWRPVIRDALFYALSIVLLIA 122
Query: 185 FVWDGQIDWFEAMVLGILYILYFVVMF 211
FV D ++ EA +L Y LY VM+
Sbjct: 123 FVHDDRLTLVEAAILVGSYGLYLGVMW 149
Score = 49.6 bits (113), Expect = 2e-04
Identities = 22/57 (38%), Positives = 37/57 (64%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+P +++ +T LA G +PE S ++R+G + V+NA+G+N IL +LGLP L+
Sbjct: 239 VPPAIIALTILAGGSSIPELVSSATVARQGRADMAVANAVGSNIFDILVSLGLPVLL 295
Score = 35.1 bits (77), Expect = 3.5
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 258 SPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACS--IFIMSRRGEGGI 315
S V G M I E+ G + SV G T LAFG PE + + + +
Sbjct: 18 SAVVEGPFMASLDRIAERMG----LSSSVAGATLLAFGTSAPELSTALVALFAEGAHAST 73
Query: 316 GVSNALGANSLAILFALGLPWLIRTVSLE 344
GV + +G+ IL +G ++R +L+
Sbjct: 74 GVGSIVGSAIFQILVVVGFAAVVRASTLD 102
>UniRef50_A5ZVY9 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 336
Score = 74.9 bits (176), Expect = 4e-12
Identities = 69/303 (22%), Positives = 133/303 (43%), Gaps = 10/303 (3%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSC 116
++ + F L ++F I F L I D+F+ I + LK+P + T +++ TS
Sbjct: 2 EQYINNAPFALVIMFLIIGFVFL-IKGADFFVEGSSSIAKKLKVPSIIIGLTIVAMGTSL 60
Query: 117 PEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYM 176
PE V+V ++ + +++ + +VGS +FN TPI + + RD+ + +
Sbjct: 61 PETAVSVTASLVHNNELAVSNVVGSNIFN--LMFVIGVCAIMTPIMVQKDTIVRDIPLSV 118
Query: 177 VNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTA 236
+ +L+ + D M+LG L F+ F +++ + A K + A
Sbjct: 119 ICALLLLGLGYLALGD-VHGMILGHLDGAVFLGAFAGYIFYMIRTAMKARTEGKKVEIEA 177
Query: 237 --SLNDNNVSVEEGIDN--KGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFL 292
L D + + + + G MT A + + ++++G+T +
Sbjct: 178 VEELEDGELKLLSYPKSILCIVGGAVAIAFGGDMTVDAA--SRIAIDLGMSQTLVGLTIV 235
Query: 293 AFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTA 352
+ G LPE + + +R+ E + V NA+G+N IL LG+ I +SL + +
Sbjct: 236 SIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIFNILMVLGIASAISPMSLISENVIDIL 295
Query: 353 VLI 355
VL+
Sbjct: 296 VLV 298
Score = 50.4 bits (115), Expect = 9e-05
Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D + I DL + Q + T +S+ TS PE +V++ E DM +G VGS +F
Sbjct: 210 DMTVDAASRIAIDLGMSQTLVGLTIVSIGTSLPELVTSVVAARKNEVDMAVGNAVGSNIF 269
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV--WDGQIDWFEAMVLGIL 202
N +P+++ V D+L+ +V SV+V F D +I E + + +
Sbjct: 270 N--ILMVLGIASAISPMSLISENVI-DILV-LVGFSVVVWFFARSDRKITRNEGIAMVAM 325
Query: 203 YILY--FVVM 210
Y++Y +++M
Sbjct: 326 YLIYTAYIIM 335
>UniRef50_Q6XR82 Cluster: Uvs037; n=1; uncultured bacterium|Rep:
Uvs037 - uncultured bacterium
Length = 354
Score = 73.3 bits (172), Expect = 1e-11
Identities = 83/345 (24%), Positives = 149/345 (43%), Gaps = 33/345 (9%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
++ +L ++ D + + + +P V T ++ TS PE V+V + F +++
Sbjct: 6 LFAGLVLLVIGADLLVKGAARLAANFGVPALVIGLTVVAFGTSAPELAVSVKAAFSGQAE 65
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL-VAFVWDGQI 191
+ I +VGS +FN +P+ I + + +DV I MV +S++ V DG I
Sbjct: 66 LAIANVVGSNIFN--ILFILGVAALISPLIISHQLIRQDVPI-MVGVSIVAVLMTLDGNI 122
Query: 192 DWFEAMVL--GILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGI 249
+ EA +L G++ +F+ K + D K V + N + V G+
Sbjct: 123 NKLEASILTIGLISYTWFLFYQGKQKGVDVSDGEVEEMLK----VNVPMWQNVLLVLGGL 178
Query: 250 DNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSR 309
+ G + A++ ++ + E+V+G+T +A G LPE + + +
Sbjct: 179 --------VLLVLGARWLVQSAVELAT--SWGVNEAVIGLTIVAAGTSLPEVVTSVVATI 228
Query: 310 RGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXX 369
+GE I V N +G+N IL LG+ L+ + L + G + AG D
Sbjct: 229 KGERDIAVGNVVGSNIFNILCVLGISGLVSPIPL-LAGEQ-------LAGFDI---PVML 277
Query: 370 XXXXXWIVLFIGKFTLRRTVGIVLGILYV--VFIVFAILVELGII 412
+ LF L R G + LYV V+I+ A+ + LG +
Sbjct: 278 GVAALCVPLFFVGAILNRMEGFLFLTLYVAYVWILIAMALSLGYL 322
>UniRef50_Q8TPA6 Cluster: Sodium/calcium exchanger protein; n=4;
Methanosarcinaceae|Rep: Sodium/calcium exchanger protein
- Methanosarcina acetivorans
Length = 350
Score = 73.3 bits (172), Expect = 1e-11
Identities = 84/343 (24%), Positives = 146/343 (42%), Gaps = 41/343 (11%)
Query: 84 NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSAL 143
+DYF+ I + L + + V T +++ TS PE ++ ++ S + IG +VGS +
Sbjct: 20 SDYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVIGNVVGSNI 79
Query: 144 FNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILY 203
N IDM + RD I + + + F ++ ++ EA + +LY
Sbjct: 80 ANVGLIVGVAALLSPMKTEIDM--LKRDGYIMLFSAVLFFVFAFNRELSMLEAGLFVLLY 137
Query: 204 ILYFVVMFNS---------MKAFVLI---DKIWAACCKKNNGVTASLNDNNVSVEEGIDN 251
I Y +F K F+ K + +K NG +D++ + + G N
Sbjct: 138 IAYVFFLFEEAEKYEGKLHFKEFITYFFKFKYINSAMQKLNGNRNRNSDSDRNSDSGNGN 197
Query: 252 K----GF-NDPSPVT---NGTTMTEKPAIDEK--NGHTFFIPESVMGMTFLAFGGCLPEA 301
+ GF D + + K ++E IP++V+G T +A G LPE
Sbjct: 198 ERLEGGFAKDIFTLVLSCAAIVIGAKYFVEESIFFAELLGIPDTVIGTTLVAVGTSLPEL 257
Query: 302 CSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL-EIQGAENTAVLINSAGI 360
+R+G G I + N +G+N I LGL L +S+ E+ T V+I + I
Sbjct: 258 VVTVSAARQGYGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMIAISLI 317
Query: 361 DFXXXXXXXXXXXXWIVLFIGK-FTLRRTVGIVLGILYVVFIV 402
+++FI + ++R G+VL + YV F+V
Sbjct: 318 ---------------LLIFISTGWEIKRWEGVVLMMFYVAFLV 345
Score = 46.8 bits (106), Expect = 0.001
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Query: 73 IYTFTL--LAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
I+T L AIV YF+ E L IP V T ++V TS PE V V +
Sbjct: 208 IFTLVLSCAAIVIGAKYFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQG 267
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+ +G ++GS + N +A T V+I +++ +L+
Sbjct: 268 YGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMI-AISLILLIFISTGW 326
Query: 190 QIDWFEAMVLGILYILYFVVMF 211
+I +E +VL + Y+ + VV+F
Sbjct: 327 EIKRWEGVVLMMFYVAFLVVLF 348
>UniRef50_P72945 Cluster: Slr0681 protein; n=7; Bacteria|Rep:
Slr0681 protein - Synechocystis sp. (strain PCC 6803)
Length = 433
Score = 72.5 bits (170), Expect = 2e-11
Identities = 59/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
+ T ++ TS PE V++ + ++D+ IG +VGS +FN TP+ +
Sbjct: 106 IIGLTIVAYGTSMPEMVVSLQAAIAGQADISIGNVVGSNIFN--VLLILGVCSIITPLIV 163
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
+ + D+ I + +L+ F WDGQI + ++L ILY + K D
Sbjct: 164 AQQLIRLDIPILIGVSGLLLMFGWDGQISRVDGVILASGAILYTTFLIRQSKKENNPDVT 223
Query: 224 WAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIP 283
K G + ++ G + + G+++ K ++ + I
Sbjct: 224 EEYL--KEFGEPVPKTGKQIFIQIAYVVGGV---ALLVLGSSLLVKSSV--AIAKSLGIS 276
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
E V+G+T +A G LPE + + S RGE I V N +G+N IL LG + +
Sbjct: 277 ELVIGLTLIAAGTSLPELATSVVASYRGERDIAVGNVVGSNIFNILAVLGFAAIFSPNGI 336
Query: 344 EIQGA 348
++ +
Sbjct: 337 QVSNS 341
Score = 51.2 bits (117), Expect = 5e-05
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 5/142 (3%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+ YVV G+ L ++ + + I + L I + V T ++ TS PE +V++
Sbjct: 245 IAYVVGGV----ALLVLGSSLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSVVA 300
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDV-LIYMVNISVLVA 184
++ E D+ +G +VGS +FN I + D+ +++ V + L
Sbjct: 301 SYRGERDIAVGNVVGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPVMFAVALVCLPV 360
Query: 185 FVWDGQIDWFEAMVLGILYILY 206
F+ ID +E + YI Y
Sbjct: 361 FITGRLIDRWEGFLFLFYYIAY 382
>UniRef50_UPI0000E491B3 Cluster: PREDICTED: similar to K-dependent
Na,Ca exchanger; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to K-dependent Na,Ca exchanger -
Strongylocentrotus purpuratus
Length = 259
Score = 72.1 bits (169), Expect = 2e-11
Identities = 40/136 (29%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP++VMG++ LA G +P+A + +++R G G + +SN +G+N + LGL W
Sbjct: 117 GYTLDIPDTVMGISLLAAGTSVPDAIASVLVARDGYGDMALSNIVGSNIFEVFICLGLLW 176
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I + + V I S G+ F + + + + L + +G++ +
Sbjct: 177 FIYGLVYQ------RPVEIASEGLLFTTVALLVTVAFILLAIHLNGWKLDKKMGVLCMCV 230
Query: 397 YVVFIVFAILVELGII 412
Y++FI AI+ ELG+I
Sbjct: 231 YLIFITIAIVWELGLI 246
>UniRef50_Q189V4 Cluster: Ca2+/Na+ antiporter; n=3; Clostridium
difficile|Rep: Ca2+/Na+ antiporter - Clostridium
difficile (strain 630)
Length = 331
Score = 72.1 bits (169), Expect = 2e-11
Identities = 68/261 (26%), Positives = 118/261 (45%), Gaps = 23/261 (8%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D FI C I + I + + AT +S AT+ PEF V+++++ + M +G VGS +
Sbjct: 20 DIFINCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIIC 79
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYI 204
N +P +D + L+ +V++ VL+ DG I ++++L I+ I
Sbjct: 80 N--TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILI 137
Query: 205 LYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPV---- 260
Y V + S+ + + K N ++ D +S ++G + +GF+ V
Sbjct: 138 FYMVNNYRSV--------VGKSDTKNRNIKNNTIKD--ISTKKGKNYRGFSVLEIVKILL 187
Query: 261 ---TNGTTMTEKPAIDEKNG---HTFF-IPESVMGMTFLAFGGCLPEACSIFIMSRRGEG 313
T M I ++G +F IP+ ++ +T +A G LPE S R+
Sbjct: 188 LFATGLIMMIIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHH 247
Query: 314 GIGVSNALGANSLAILFALGL 334
I V N LGAN L I+ + +
Sbjct: 248 EISVGNILGANILNIVSVIAV 268
Score = 46.0 bits (104), Expect = 0.002
Identities = 26/137 (18%), Positives = 61/137 (44%), Gaps = 1/137 (0%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T ++ I+ + I +I L IPQ + + T +++ TS PE ++ + ++
Sbjct: 191 TGLIMMIIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEIS 250
Query: 135 IGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWF 194
+G I+G+ + N PI R + +I ++ I V++ + ++
Sbjct: 251 VGNILGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLI-VIIPTLKSNKLSRI 309
Query: 195 EAMVLGILYILYFVVMF 211
+ +++ Y LY +++
Sbjct: 310 QGILMLFTYFLYISILY 326
>UniRef50_P45394 Cluster: Inner membrane protein yrbG; n=25;
Enterobacteriaceae|Rep: Inner membrane protein yrbG -
Escherichia coli (strain K12)
Length = 325
Score = 70.5 bits (165), Expect = 8e-11
Identities = 66/265 (24%), Positives = 112/265 (42%), Gaps = 19/265 (7%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL + D + ++C IP + T +S+ TS PE V++ ++ + D+ +GT
Sbjct: 13 LLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGT 72
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV-WDGQIDWFEA 196
+GS + N + D V R L M+ +SV+ V +DGQ+ +
Sbjct: 73 ALGSNIINILLILGLAALVRPFTVHSD---VLRRELPLMLLVSVVAGSVLYDGQLSRSDG 129
Query: 197 MVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSV-EEGIDNKGFN 255
+++L+ V++ + I K+ A + G + + + +G F
Sbjct: 130 -----IFLLFLAVLW-----LLFIVKL--ARQAERQGTDSLTREQLAELPRDGGLPVAFL 177
Query: 256 DPSPVTNGTTMTEKPAIDEKN--GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEG 313
+ + +D + F I E MG+T +A G LPE + R+GE
Sbjct: 178 WLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGEN 237
Query: 314 GIGVSNALGANSLAILFALGLPWLI 338
I V N +GAN I+ LGLP LI
Sbjct: 238 DIAVGNIIGANIFNIVIVLGLPALI 262
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
TF IP ++GMT ++ G LPE S + + V ALG+N + IL LGL L+
Sbjct: 32 TFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALV 91
Query: 339 R--TVSLEIQGAENTAVLINS 357
R TV ++ E +L+ S
Sbjct: 92 RPFTVHSDVLRRELPLMLLVS 112
Score = 33.9 bits (74), Expect = 8.1
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP 167
T +++ TS PE + E+D+ +G I+G+ +FN TP ID
Sbjct: 214 TAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFN--IVIVLGLPALITPGEIDPLA 271
Query: 168 VTRDVLIYMVNISVLVAFV 186
+RD + M+ +S++ A +
Sbjct: 272 YSRDYSV-MLLVSIIFALL 289
>UniRef50_A3JJ87 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Marinobacter sp. ELB17|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Marinobacter sp. ELB17
Length = 328
Score = 69.7 bits (163), Expect = 1e-10
Identities = 67/332 (20%), Positives = 141/332 (42%), Gaps = 38/332 (11%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
+ FG++ L + D I I E + + AAT ++ TS PE F +V +
Sbjct: 17 IFFGVW----LLVKGGDLTIDSAVRIAERSGLSKMFIAATIVAFGTSAPELFTSVNANIS 72
Query: 129 TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
+ + +G ++GS + N PI D + D L+ ++ + VW
Sbjct: 73 GFAGISVGNVIGSNIANVLMVIGISAMIA--PIVFDRKKAQVDTLVMILATVAMAVAVWA 130
Query: 189 GQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEG 248
G + + + + + Y + + K + +D+ + G AS + V V G
Sbjct: 131 GLLPRWAGLAMVFAIVAYVTYQYKASK--IEVDE-------DDEGEDASPGNPFVMVTIG 181
Query: 249 IDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMS 308
I + + G+ + + A+ G +PE+V+GMT +AFG LPE + +
Sbjct: 182 I--------ATLVIGSEVLVQGAV--AGGFALGVPEAVIGMTVIAFGTSLPELTASVAAA 231
Query: 309 RRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXX 368
R+G+ + + +G+N IL + + +++ + ++ + + +++ + F
Sbjct: 232 RKGQSDMIIGGIVGSNIFNILSVMAITAVVKPLVIDPRFGQFDLLIVLAVTFVFAL---- 287
Query: 369 XXXXXXWIVLFIGKFTLRRTVGIVLGILYVVF 400
+LF+G+ + R G ++ + Y++F
Sbjct: 288 -------FLLFVGR--IGRIAGGIMAVSYLLF 310
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L +P+ V T ++ TS PE +V + +SDM IG IVGS +FN
Sbjct: 203 LGVPEAVIGMTVIAFGTSLPELTASVAAARKGQSDMIIGGIVGSNIFN--ILSVMAITAV 260
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAF-VWDGQIDWFEAMVLGILYILYFVVMFNSM-K 215
P+ ID R D+LI + V F ++ G+I ++ + Y+L+ ++ +
Sbjct: 261 VKPLVIDPRFGQFDLLIVLAVTFVFALFLLFVGRIGRIAGGIMAVSYLLFTFAQYSGVAD 320
Query: 216 AFV 218
AFV
Sbjct: 321 AFV 323
>UniRef50_A5ZN74 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 305
Score = 69.3 bits (162), Expect = 2e-10
Identities = 61/280 (21%), Positives = 122/280 (43%), Gaps = 21/280 (7%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
+L I D+F+ + LKIP + T +++ TS PE V++ + +D+ +
Sbjct: 11 VLLIKGADFFVEGSSSLARFLKIPSVIIGLTIVAMGTSAPEASVSINAALAGNNDIAVSN 70
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
I+GS +FN D+ + RD+ + ++ +L + +G++ E +
Sbjct: 71 IIGSNIFNGLIVVGICAFISGFKTNKDI--LKRDMPVNILITVILCIMIANGKLSRIEGI 128
Query: 198 VLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDP 257
+L I Y + M + + K C +T L + + G+ F
Sbjct: 129 LLLAGMIFYILNMIRTA-----LKK--RTECPAEQSIT--LYKALLFIIGGLAAVIFGGN 179
Query: 258 SPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGV 317
V N + + +F + ++ +G+T +A G LPE + + +R+G+ G+ +
Sbjct: 180 LVVNNASQIAV----------SFGVSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLAL 229
Query: 318 SNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINS 357
NA+G+N ILF LG+ I + + + + +L+ S
Sbjct: 230 GNAIGSNIFNILFILGMSATISPLHILSESVIDCGILLIS 269
Score = 38.7 bits (86), Expect = 0.28
Identities = 24/112 (21%), Positives = 46/112 (41%), Gaps = 2/112 (1%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ QN T +++ TS PE ++++T +S + +G +GS +FN +
Sbjct: 194 VSQNFIGLTIVAIGTSLPELVTSIVATRKGDSGLALGNAIGSNIFN--ILFILGMSATIS 251
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
P+ I V ++ + I + V + E + YI Y +F
Sbjct: 252 PLHILSESVIDCGILLISGILLFVFAFTKKSVSRMEGAACALAYIGYTAYLF 303
>UniRef50_UPI00015B4400 Cluster: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger - Nasonia
vitripennis
Length = 418
Score = 67.7 bits (158), Expect = 5e-10
Identities = 40/136 (29%), Positives = 71/136 (52%), Gaps = 6/136 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP VMG+TFLA G +P+ + I++R+G G + VS+++G+N + L +PW
Sbjct: 285 GDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPVPW 344
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ + I G T V +NS G+ + + K+ + + +G + +L
Sbjct: 345 LLYGL---IYG---TPVEVNSVGMVCSIAILFCMLLFVILSIAFFKWRMNKGLGFTMFLL 398
Query: 397 YVVFIVFAILVELGII 412
Y VF+ +++ E +I
Sbjct: 399 YFVFVAVSLMFEYELI 414
Score = 35.5 bits (78), Expect = 2.7
Identities = 16/53 (30%), Positives = 29/53 (54%)
Query: 93 LICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
++ + ++IP V TF++ TS P+ +VI DM + + VGS +F+
Sbjct: 283 VVGDTVQIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFD 335
>UniRef50_Q9UYE7 Cluster: Na+/Ca2+ exchange integral membrane
protein; n=3; Pyrococcus|Rep: Na+/Ca2+ exchange integral
membrane protein - Pyrococcus abyssi
Length = 314
Score = 67.7 bits (158), Expect = 5e-10
Identities = 64/268 (23%), Positives = 121/268 (45%), Gaps = 25/268 (9%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
+L I +D F+ I E + + + A S+AT+ PE V+ IS++ S + +G
Sbjct: 15 ILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGIALGN 74
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-AFVWDGQIDWFEA 196
VGSAL N TP+ +D V + + M+ +++ + +G+I E
Sbjct: 75 AVGSALAN--IALILGISAMITPLKVD--EVANENSLIMLGVTLYAWLLMINGEISRIEG 130
Query: 197 MVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFND 256
+ L ++Y + ++ + V +++I +++ G NV + I F
Sbjct: 131 LTLVLIYGAFLYYLY---RKHVKLEEIE----EESRG--------NVIKDIAI---LFLS 172
Query: 257 PSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIG 316
V G + A+ G IPE V+G+T ++ G LPE + + +G +
Sbjct: 173 GGMVILGAELVVDSAVKIARGAG--IPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVS 230
Query: 317 VSNALGANSLAILFALGLPWLIRTVSLE 344
V N +GA+ + IL +G+ +IR + ++
Sbjct: 231 VGNIIGADIIDILMVIGIASIIRPIKVD 258
Score = 40.7 bits (91), Expect = 0.071
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
TF + E ++ + + LPEA I S +G GI + NA+G+ I LG+ +I
Sbjct: 34 TFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGIALGNAVGSALANIALILGISAMI 93
Query: 339 RTVSLEIQGAENTAVLI 355
+ ++ EN+ +++
Sbjct: 94 TPLKVDEVANENSLIML 110
>UniRef50_P34322 Cluster: Putative sodium/calcium exchanger 7
precursor (Na(+)/Ca(2+)-exchange protein 7); n=2;
Caenorhabditis|Rep: Putative sodium/calcium exchanger 7
precursor (Na(+)/Ca(2+)-exchange protein 7) -
Caenorhabditis elegans
Length = 672
Score = 67.3 bits (157), Expect = 7e-10
Identities = 39/150 (26%), Positives = 75/150 (50%), Gaps = 8/150 (5%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFF---VNVIS 125
V++ + F +++ +D+F P + I L+I ++VA TFM+ P+ F +V+S
Sbjct: 95 VIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIASVLS 154
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-A 184
+ ++D+ +G + G LF +P +++ RD+L Y+V +S L
Sbjct: 155 SPTPKADLALGELFGGGLF--VTTMVVSTIILTSPFDVEVFSTIRDLLFYLVALSFLAFC 212
Query: 185 FVWDGQID-WFEAMVLGILYILYFVVMFNS 213
FV+ ++ W LG LY+LY + + +
Sbjct: 213 FVFYNRVTLWMPLTFLG-LYLLYVITVIGA 241
Score = 44.0 bits (99), Expect = 0.008
Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ V+G+T LA+ + + + + ++G + ++ A+G +L GLP+ I
Sbjct: 545 VSHEVLGLTILAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFTIA-- 602
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
++QG + ++ IN I + + KF L+R VL +Y+ FI
Sbjct: 603 --KLQG-KYISMTINPT-YRLLILFLAISLLATLIGIPVQKFRLQRPHAAVLISIYIAFI 658
Query: 402 VFAILVELGII 412
VF IL E G++
Sbjct: 659 VFVILSETGVL 669
>UniRef50_A6TQK1 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Na+/Ca+
antiporter, CaCA family - Alkaliphilus metalliredigens
QYMF
Length = 334
Score = 66.9 bits (156), Expect = 9e-10
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 17/267 (6%)
Query: 70 VFGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
VF ++ L+ I+ D+F+ + + +P + AT +S+AT+ PE V+VI+T
Sbjct: 6 VFFLFCMGLIMIIKGGDWFVESAVWVAKVTGVPNVLIGATIVSIATTLPELLVSVIATQQ 65
Query: 129 TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
D+ IG ++GS + N +PI ++ + + ++++ F+ D
Sbjct: 66 HYYDVAIGNVIGSMICN--VGLILGLTTLFSPIKLNRSGFAIRGFFMLGSTALMLFFLRD 123
Query: 189 GQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGV-TASLNDNNVSVEE 247
I E +L+ +Y ++ +++ F K + V S + +
Sbjct: 124 RMISPREGTWFIVLFTIYILI---NLQEFNKNQKRVPHVLNQEQDVPQGSASKKIIMFIV 180
Query: 248 GIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIM 307
G V NG + + +PE V+ +T +A G LPE +
Sbjct: 181 GAVFIALGARLLVNNGVII----------ANILGVPEQVVSLTLIALGTSLPELTTAISS 230
Query: 308 SRRGEGGIGVSNALGANSLAILFALGL 334
+G GI V N LGAN L I+ LGL
Sbjct: 231 VVKGHQGISVGNILGANILDIVMVLGL 257
>UniRef50_A7SWG6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 40/147 (27%), Positives = 69/147 (46%), Gaps = 2/147 (1%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A ++ V ++ F +L I +DYF P + +I + L++ QNVA TF++ P+ F +
Sbjct: 34 ALVILFVLMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIF-SA 92
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
I+ S +G+ +F ++ RP TRDVL Y+ +S +
Sbjct: 93 IAAVSAHSKNPNAAQLGAGIF-VTTVVVGSVTLCTGGFHLNNRPFTRDVLFYLGAVSWMF 151
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
++ +I EA+ I Y Y VV+
Sbjct: 152 ITMYRQRITMLEAIGFIIFYFAYVVVV 178
>UniRef50_Q4P4P0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1117
Score = 66.1 bits (154), Expect = 2e-09
Identities = 36/147 (24%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Query: 60 LRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEF 119
LR LL +++ ++ F+ + +V +D+F P + I L + ++ A TF++ P+
Sbjct: 176 LRFLRLLLILMWMLFLFSWVGVVASDFFCPNLSTIASRLGLNESTAGVTFLAFGNGSPDV 235
Query: 120 FVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNI 179
F + + IG ++G+A F P ++ P RDV + V +
Sbjct: 236 FSTFGAMKTDSGSLAIGELLGAASF--IVSVISGSMMLIAPFKVNAWPFCRDVGFFTVAV 293
Query: 180 SVLVAFVWDGQIDWFEAMVLGILYILY 206
++ + F++DG++ E + L LY+LY
Sbjct: 294 ALTLTFLFDGKLRRIETIALICLYLLY 320
Score = 37.1 bits (82), Expect = 0.87
Identities = 20/55 (36%), Positives = 26/55 (47%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
ES G+TFLAFG P+ S F + G + + LGA S + G LI
Sbjct: 218 ESTAGVTFLAFGNGSPDVFSTFGAMKTDSGSLAIGELLGAASFIVSVISGSMMLI 272
>UniRef50_Q8DEA9 Cluster: Ca2+/Na+ antiporter; n=23;
Gammaproteobacteria|Rep: Ca2+/Na+ antiporter - Vibrio
vulnificus
Length = 321
Score = 65.7 bits (153), Expect = 2e-09
Identities = 53/251 (21%), Positives = 110/251 (43%), Gaps = 24/251 (9%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ ++ I V T +++ +S PE V+ + ++D +G ++GS + N
Sbjct: 29 LARNIGISPLVIGMTILAMGSSAPEMMVSATAALDGKTDTAVGNVLGSNIAN--IALILG 86
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVA-FVWDGQIDWFEAMVLGILYILYFVVMFN 212
P++I+ V R+ L M+ +++L +WD + ++E ++L +L+ L+ V M
Sbjct: 87 ITALVRPLSINSAVVRRE-LPLMIGVTILAGILLWDSHLGFYEGVLLFVLFTLFLVAMLQ 145
Query: 213 SMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPA- 271
+ ++ A L + + +G+ N + G + A
Sbjct: 146 ISR-------------REQKTGDAFLEEQESEIPQGVSNP--KAAMWIVIGLILLPLAAD 190
Query: 272 --IDEK--NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLA 327
+D F + + V+G+T +A G LPE + + +GE + V N +G+N
Sbjct: 191 MLVDNAVIIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDDMAVGNIIGSNVFN 250
Query: 328 ILFALGLPWLI 338
IL +G+P ++
Sbjct: 251 ILAVMGIPGIL 261
Score = 39.5 bits (88), Expect = 0.16
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
+++V G+ L A D + +I + + V T ++V TS PE ++
Sbjct: 176 MWIVIGLILLPLAA----DMLVDNAVIIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGA 231
Query: 127 FLTESDMGIGTIVGSALFN 145
E DM +G I+GS +FN
Sbjct: 232 LKGEDDMAVGNIIGSNVFN 250
Score = 38.3 bits (85), Expect = 0.38
Identities = 21/58 (36%), Positives = 29/58 (50%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
V+GMT LA G PE + G+ V N LG+N I LG+ L+R +S+
Sbjct: 39 VIGMTILAMGSSAPEMMVSATAALDGKTDTAVGNVLGSNIANIALILGITALVRPLSI 96
>UniRef50_A4EMZ0 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Roseobacter sp. CCS2|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Roseobacter sp. CCS2
Length = 326
Score = 65.7 bits (153), Expect = 2e-09
Identities = 76/334 (22%), Positives = 143/334 (42%), Gaps = 36/334 (10%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
+ FG+Y L I D+ + + E + AT +S TS PE F +V +
Sbjct: 17 MAFGLY----LLIKGGDWTVDAAVFVAERTGLSPLFIGATIVSFGTSVPELFTSVNANLQ 72
Query: 129 TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-AFVW 187
+ +G ++GS + N + D + + +D+ + + +++V +
Sbjct: 73 GYPGISLGNVLGSNVANILLVLGATAFVFK--VTADPKHLAKDLAMMLFATAIMVYGMLT 130
Query: 188 DGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
D F ++ IL + FVV + VL + + G+T ++ V +
Sbjct: 131 DSFSQVFGLIMFAIL--VTFVVYQYKTDSIVLEED---DDDDEGPGIT-TMKGAVVILLG 184
Query: 248 GIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIM 307
G+ + + G+ + K A+ + G +PE+V+GMT +AFG LPE +
Sbjct: 185 GV--------AALAVGSELLVKGAV--QTGSAIGVPEAVIGMTVVAFGTSLPELSTCIAA 234
Query: 308 SRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXX 367
+R+ G+ + N +G+N+ IL + L I+ + ++ VL+ G++
Sbjct: 235 ARKQSVGLILGNIIGSNTFNILSIIALTAAIKPLDVD-------PVLL---GMELWVTVA 284
Query: 368 XXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
W + +GK T R +GI + + YVVFI
Sbjct: 285 VAVVFSAW-MFAVGKLT--RPIGIAMMVAYVVFI 315
>UniRef50_Q0F1D4 Cluster: Ca2+/Na+ antiporter; n=1; Mariprofundus
ferrooxydans PV-1|Rep: Ca2+/Na+ antiporter -
Mariprofundus ferrooxydans PV-1
Length = 322
Score = 64.5 bits (150), Expect = 5e-09
Identities = 60/274 (21%), Positives = 118/274 (43%), Gaps = 16/274 (5%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L V I L I D F+ + ++L++P V T +S+ TS PE V+ ++
Sbjct: 1 MLLAVAAIAVGVALLIWGADRFVDGAASVAKNLRVPPMVIGLTIVSLGTSLPEMIVSAMA 60
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
D+GIG ++GS + N P+ + + R++ + + + A
Sbjct: 61 ALDGNRDLGIGNVLGSNIANIGLVLGITALVI--PLTVKSMTLRREMPVMFMVTLLAFAL 118
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSV 245
+ DG + + GI+ I+ V++ + L D+ + T S+ D +
Sbjct: 119 MADGALSRGD----GIILIIGLVLLLAWITMLGLRDRDDPLVAE----FTDSIPDQ---M 167
Query: 246 EEGIDNKGFN-DPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSI 304
G+ F + + + M A++ H + + ++G+T +A G LPE +
Sbjct: 168 SMGMSLLWFVVGLALLIISSRMVVWGAVEI--AHLLGVSDLIIGLTIVAIGTSLPELVAS 225
Query: 305 FIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+ + +GE + + N +G+N +L L +P LI
Sbjct: 226 LVSALKGEADLAIGNVIGSNMFNLLAVLAMPALI 259
Score = 45.2 bits (102), Expect = 0.003
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 55 FTD---EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMS 111
FTD +Q+ G LL+ V G+ LL I VE I L + + T ++
Sbjct: 159 FTDSIPDQMSMGMSLLWFVVGL---ALLIISSRMVVWGAVE-IAHLLGVSDLIIGLTIVA 214
Query: 112 VATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ TS PE +++S E+D+ IG ++GS +FN
Sbjct: 215 IGTSLPELVASLVSALKGEADLAIGNVIGSNMFN 248
>UniRef50_Q7UX07 Cluster: Putative uncharacterized protein; n=1;
Pirellula sp.|Rep: Putative uncharacterized protein -
Rhodopirellula baltica
Length = 339
Score = 62.9 bits (146), Expect = 2e-08
Identities = 67/278 (24%), Positives = 121/278 (43%), Gaps = 24/278 (8%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL ++ ++ + + K+ T +S+ TS PE V+ + ++D+ IG
Sbjct: 20 LLLLIGGEWVVRGASRLAIAAKLSPLFVGLTVVSLGTSAPEMAVSFATALRGQADITIGN 79
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTR-DV-LIYMVNISVLVAFVWDGQIDWFE 195
+VGS LFN P+ +D R +TR DV ++ I++LVA + +G I F+
Sbjct: 80 VVGSNLFN--MLMIVGFSALFAPLPVD-RQITRFDVPVMIAATIAMLVASL-NGIIGRFD 135
Query: 196 AMVLGILYILYFVVMFNSMKAF--------VLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
+VL ++ I YF + + K +L +I + A + + +
Sbjct: 136 GIVLILIMIGYFAISYRLGKKSGSQPISDDLLTPEIVEEAAETLGRRVAVIVWQLILLSA 195
Query: 248 GIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIM 307
G+ F V +M + E V+G+T ++ G LPE +
Sbjct: 196 GVAALVFGCDLFVDGAVSMARILGVSE----------LVIGLTIVSAGTSLPELVTSVAA 245
Query: 308 SRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
+ +GE GI + NA+G+ +L I+ LG+ +I L +
Sbjct: 246 TIKGERGIAIGNAVGSTTLNIVAVLGITSVIAPSGLNV 283
Score = 33.9 bits (74), Expect = 8.1
Identities = 16/60 (26%), Positives = 30/60 (50%)
Query: 287 MGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQ 346
+G+T ++ G PE F + RG+ I + N +G+N +L +G L + ++ Q
Sbjct: 47 VGLTVVSLGTSAPEMAVSFATALRGQADITIGNVVGSNLFNMLMIVGFSALFAPLPVDRQ 106
>UniRef50_Q17ND1 Cluster: Na/Ca exchanger; n=2; Culicidae|Rep: Na/Ca
exchanger - Aedes aegypti (Yellowfever mosquito)
Length = 583
Score = 62.9 bits (146), Expect = 2e-08
Identities = 34/138 (24%), Positives = 68/138 (49%), Gaps = 3/138 (2%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
I FT+LA + +F P + +I + L I ++VA T ++ P+ F +S +++
Sbjct: 85 ILCFTMLATTADQFFCPVLAVIAKTLSISESVAGVTILAFGNGSPDLF-TAVSNPNDDTE 143
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+ G ++G+ LF P + V RDV+ ++ +S + +D +
Sbjct: 144 LMFGELLGAGLF--VVGIVAGTILVIRPFHVYSAAVVRDVVFFIFAVSWITVCAYDERFT 201
Query: 193 WFEAMVLGILYILYFVVM 210
+A+V+ ++Y+LY VV+
Sbjct: 202 LSDAIVVVVVYVLYLVVV 219
Score = 44.0 bits (99), Expect = 0.008
Identities = 29/131 (22%), Positives = 62/131 (47%), Gaps = 4/131 (3%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ +S++G++ LA+G + + S +++RG G + + G + LG ++R
Sbjct: 442 LSKSMLGLSVLAWGNSIGDLFSNIALAKRGYGKMAFAACFGGPLFNLCLGLGSTMIVRAS 501
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
+ ++ A A + VL + F RR++G+++ I+Y++F+
Sbjct: 502 KKK----DHVAFSREGAMGENCEWFLVQLLATILFVLMLTGFQGRRSLGLIMIIIYLMFL 557
Query: 402 VFAILVELGII 412
+F L EL +I
Sbjct: 558 LFCTLGELEVI 568
>UniRef50_A0DG97 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_5,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 536
Score = 62.9 bits (146), Expect = 2e-08
Identities = 42/143 (29%), Positives = 66/143 (46%), Gaps = 2/143 (1%)
Query: 74 YTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDM 133
+ F LA +DY P V I E K+ Q A T ++ A P+FF V+++ + +
Sbjct: 57 FLFNFLARTVDDYLSPAVTFIAEYFKMSQTFAGVTLIAFANGVPDFFCAVLASQDDDGIL 116
Query: 134 -GIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+G+I GS L I P RD+L V I +L+ F + GQI+
Sbjct: 117 IAVGSIFGSCLCMTTLVFGAVILFSGI-IKAQKVPFIRDILFNGVAIFLLMVFAFIGQIN 175
Query: 193 WFEAMVLGILYILYFVVMFNSMK 215
+ A+ LY++Y VV+ + K
Sbjct: 176 HYMAIGFCSLYLVYIVVVLANEK 198
>UniRef50_Q1JVA8 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Desulfuromonas acetoxidans DSM
684|Rep: K+-dependent Na+/Ca+ exchanger related-protein
- Desulfuromonas acetoxidans DSM 684
Length = 314
Score = 62.5 bits (145), Expect = 2e-08
Identities = 57/241 (23%), Positives = 104/241 (43%), Gaps = 15/241 (6%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
+ T +S ATS PE V++++ SD+ +G IVGS + N P+ +
Sbjct: 39 IIGMTIVSFATSMPEMMVSLLAVGKGSSDIAVGNIVGSNIANIGLILGTSALLM--PLNV 96
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
+ R++ I +V SVL DG ++ + ++L +L L+ + L +
Sbjct: 97 PRGLLWRELPIMIVATSVLYGLCVDGGLNRADGVILLVLLALFIGYCLRFARQAGLNPEA 156
Query: 224 WAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIP 283
+ + + + + V GI G V++ + + E FI
Sbjct: 157 PESLVETE---VSHRGRDVLYVVGGIVGLGVGANWMVSSAVIIARSIGLSE-----LFI- 207
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
GMT +A G LPE + + + +GE I + N +G+N ILF LG+ + + +++
Sbjct: 208 ----GMTIVALGTSLPELAASLMSAAKGEMDISIGNVIGSNIFNILFVLGVCPIFQPIAV 263
Query: 344 E 344
E
Sbjct: 264 E 264
Score = 53.2 bits (122), Expect = 1e-05
Identities = 40/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Query: 51 PDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFM 110
P+ + E +G +LYVV GI L + N + + +I + + + T +
Sbjct: 157 PESLVETEVSHRGRDVLYVVGGIVG---LGVGAN-WMVSSAVIIARSIGLSELFIGMTIV 212
Query: 111 SVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTR 170
++ TS PE +++S E D+ IG ++GS +FN PIA++ +
Sbjct: 213 ALGTSLPELAASLMSAAKGEMDISIGNVIGSNIFN--ILFVLGVCPIFQPIAVEPSILRL 270
Query: 171 DVLIYMVNISVLVAFVWDGQ-IDWFEAMVLGILYILYFVVM 210
++ + M+ LV W I ++ VL + Y+L+ V M
Sbjct: 271 ELPVVMLFSVALVPLCWHRHVIGRWKGAVLVVSYVLFIVAM 311
>UniRef50_Q965R5 Cluster: Na/ca exchangers protein 10; n=2;
Caenorhabditis|Rep: Na/ca exchangers protein 10 -
Caenorhabditis elegans
Length = 668
Score = 62.5 bits (145), Expect = 2e-08
Identities = 37/148 (25%), Positives = 74/148 (50%), Gaps = 8/148 (5%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFF---VN 122
++ +++ ++ F ++ +V +D+F P + I LKI +++A TF++ P+ F +
Sbjct: 105 IISIIYLLFLFVVMTVVADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIAS 164
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV-NISV 181
VI+T ++D+ IG I+G +F IAI RD++ +++ +I +
Sbjct: 165 VITTPKPKADLAIGDIIGGGIFVTTVVLSAIILTKSFRIAI--LATIRDIVFFIIADIFL 222
Query: 182 LVAFVWDGQID-WFEAMVLGILYILYFV 208
+ F+ ++ W LG LY Y V
Sbjct: 223 AIWFLTFNHVEIWMPLTFLG-LYAAYVV 249
>UniRef50_Q2AF76 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Halothermothrix orenii H 168|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Halothermothrix orenii H 168
Length = 383
Score = 62.1 bits (144), Expect = 3e-08
Identities = 64/250 (25%), Positives = 107/250 (42%), Gaps = 18/250 (7%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L +P+ + AT +S+ T+ PE V+V++ D+ +G VGS + +
Sbjct: 73 LGVPKVIIGATIVSLGTTLPEAAVSVLAAINGNPDLALGNAVGSIIADTGLIIGVAALLG 132
Query: 158 XTPIA--IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMK 215
P++ I R V ++ V + V I + V +L ILY +++S+K
Sbjct: 133 SLPVSKMIVNRQGRIQVWAGILLALVSLPLVSGSNIPQWIGWVFIVLLILY---IYSSIK 189
Query: 216 AFVLIDKIWAACCKKNNGVTASLN---DNNVSVEEGIDNKGFNDPSPVTN---------G 263
D A + G A+ ++VSVE I + + G
Sbjct: 190 WTQKTDTGQTAATSISRGSNANQPTPAQSDVSVEITISEDSDSLVLRIFKLFAGIFLVIG 249
Query: 264 TTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA 323
++ PA+ E IPES++ T +AFG LPE + R+G G + V N +GA
Sbjct: 250 SSKVLIPAV-EITAIRIGIPESIIAATLVAFGTSLPELMTAITAVRKGHGELAVGNIVGA 308
Query: 324 NSLAILFALG 333
+ L +LF +G
Sbjct: 309 DILNVLFVVG 318
Score = 49.2 bits (112), Expect = 2e-04
Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 4/149 (2%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L+ +F ++ L I + IP VE+ + IP+++ AAT ++ TS PE + +
Sbjct: 233 LVLRIFKLFAGIFLVIGSSKVLIPAVEITAIRIGIPESIIAATLVAFGTSLPELMTAITA 292
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
++ +G IVG+ + N + + R + MV I V
Sbjct: 293 VRKGHGELAVGNIVGADILNVLFVVGSAASVTAGGLNVPAN-FYRLQIPTMVIILVTFRL 351
Query: 186 VWDG---QIDWFEAMVLGILYILYFVVMF 211
G +I E +VL +LY++Y ++ +
Sbjct: 352 FSRGRNEEITKKEGIVLFLLYVIYLILNY 380
>UniRef50_O16241 Cluster: Na/ca exchangers protein 8; n=3;
Caenorhabditis|Rep: Na/ca exchangers protein 8 -
Caenorhabditis elegans
Length = 703
Score = 62.1 bits (144), Expect = 3e-08
Identities = 35/147 (23%), Positives = 76/147 (51%), Gaps = 8/147 (5%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFF---VNVIS 125
+++ I+ F +++ + +D+F P + I LK+ +++A TF++ P+ F +V+S
Sbjct: 109 IIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSISSVLS 168
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNIS-VLVA 184
T ++ + +G + G+++F +AI P RD++ YM+ ++ +
Sbjct: 169 TPKPKAALALGDLFGTSIFVTTVVLAIIIFTKSFKVAI--IPTLRDLIFYMITLAFITFC 226
Query: 185 FVWDGQID-WFEAMVLGILYILYFVVM 210
F+ +I+ W A LGI Y +Y + +
Sbjct: 227 FLKFDKIEVWMPATFLGI-YAVYLLTV 252
Score = 43.6 bits (98), Expect = 0.010
Identities = 26/131 (19%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ + ++G+T +++ C+ + + + ++G + ++ A+G +L GLP+ I +
Sbjct: 576 LSQELLGLTVMSWSDCIGDIVADIAVIKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIASA 635
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
QG + ++IN ++ LFI +FT+R + L +++ F+
Sbjct: 636 ----QGKQ-IDLIINPV-YRILLLFLGISLVTTFVALFIERFTVRWPHAVALIFIFINFV 689
Query: 402 VFAILVELGII 412
+F L E ++
Sbjct: 690 IFVCLAEFHVL 700
>UniRef50_P34315 Cluster: Putative sodium/calcium exchanger 6
precursor (Na(+)/Ca(2+)-exchange protein 6); n=2;
Caenorhabditis|Rep: Putative sodium/calcium exchanger 6
precursor (Na(+)/Ca(2+)-exchange protein 6) -
Caenorhabditis elegans
Length = 590
Score = 60.5 bits (140), Expect = 8e-08
Identities = 35/143 (24%), Positives = 70/143 (48%), Gaps = 8/143 (5%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFF---VNVIS 125
V++ + F +++ +D+F P + I L+I ++VA TFM+ P+ F +V+S
Sbjct: 104 VIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLS 163
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-A 184
+ ++D+ +G + G+ LF P ++ RD+ Y+V ++ L
Sbjct: 164 SPTPKADLALGELFGAGLF--VTTMVLAVTIFTRPFKAEVFSSIRDIAFYLVALAFLAFC 221
Query: 185 FVWDGQID-WFEAMVLGILYILY 206
FV+ ++ W LG+ Y++Y
Sbjct: 222 FVYYDHVEIWMPITFLGV-YLIY 243
Score = 40.3 bits (90), Expect = 0.093
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ V+G+T LA+ + + + ++++G + ++ A+G +L GLP+ I
Sbjct: 463 VSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTI--- 519
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
+IQG ++ +++IN I +F K+ LRR L +Y+ F
Sbjct: 520 -AKIQG-KSISMIINPT-YRLLMLFLAISLIFTLIAMFAQKYFLRRIHSYSLVFIYISFF 576
Query: 402 VF 403
VF
Sbjct: 577 VF 578
>UniRef50_A6VY07 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
n=2; Marinomonas|Rep: Na+/Ca+ antiporter, CaCA family
precursor - Marinomonas sp. MWYL1
Length = 332
Score = 60.1 bits (139), Expect = 1e-07
Identities = 56/262 (21%), Positives = 116/262 (44%), Gaps = 19/262 (7%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
+L ++ +D FI L+ E L + + T ++ TS PE V+ I+ ++ +G
Sbjct: 25 ILLVMSSDKFIEHSALVAEKLNVNPMIIGITLVAFGTSAPEMVVSAIAALDNAPEIAVGN 84
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF-VWDGQIDWFEA 196
++GS + N PIA + T++V + + I++L F ++D + ++
Sbjct: 85 VLGSNIANIALVFGITLLFSAIPIASGLS--TKEVPLVLA-ITLLAGFLLYDQTLGVWDG 141
Query: 197 MVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFND 256
++L +I+ ++ K ++K +++G +S++ + + G+
Sbjct: 142 VILIAAFIIILTILLRGSKD---LEKDLKEGLPEDDG--SSVSKSLIIALIGL------- 189
Query: 257 PSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIG 316
+ + + + AI + E V+G+T +A G LPE + R+G I
Sbjct: 190 -AVLIGSSKLLVWGAIGIAT--ALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIA 246
Query: 317 VSNALGANSLAILFALGLPWLI 338
+ N LG+N + L LP L+
Sbjct: 247 IGNILGSNIFNLATVLPLPALL 268
Score = 35.9 bits (79), Expect = 2.0
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I L + + V T ++V TS PE +V S D+ IG I+GS +FN
Sbjct: 206 IATALGVSELVIGLTIVAVGTSLPELAASVSSVRKGHHDIAIGNILGSNIFN--LATVLP 263
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVA 184
P +D ++RD +++ ++V +A
Sbjct: 264 LPALLAPGLVDQSVISRD-FPWVLGLTVALA 293
>UniRef50_A6DS00 Cluster: Sodium/calcium exchanger; n=1;
Lentisphaera araneosa HTCC2155|Rep: Sodium/calcium
exchanger - Lentisphaera araneosa HTCC2155
Length = 319
Score = 60.1 bits (139), Expect = 1e-07
Identities = 53/238 (22%), Positives = 104/238 (43%), Gaps = 14/238 (5%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
V T ++ TS PE V + +T D+ +G ++GS + N PIA+
Sbjct: 39 VVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNICN--IGLVLAIAALLKPIAV 96
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
+ + DV + ++ + DGQ+D+ ++L + + Y +F S+K + K
Sbjct: 97 QSQLIKIDVPVSIIAALAFFLQIQDGQLDFSNGIILFAMVVCY---VFFSLK----MSKK 149
Query: 224 WAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIP 283
++ +D + G+ G + VT G ++ A G +
Sbjct: 150 EGKEVEEEFDEEVKPSDKSTLALFGLIFAGL---AGVTYGGSIFVDGASTIAAG--LGVS 204
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
++V+G+T +A G LPE + + S +G G + + N +G+ +L +G+ +I T+
Sbjct: 205 QAVIGLTIVALGTSLPELAASIMASLKGHGDMALGNVIGSCIFNLLAIMGITSMIETI 262
Score = 46.8 bits (106), Expect = 0.001
Identities = 32/156 (20%), Positives = 67/156 (42%), Gaps = 3/156 (1%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATS 115
DE+++ +FG+ L + F+ I L + Q V T +++ TS
Sbjct: 159 DEEVKPSDKSTLALFGLIFAGLAGVTYGGSIFVDGASTIAAGLGVSQAVIGLTIVALGTS 218
Query: 116 CPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIY 175
PE +++++ DM +G ++GS +FN T A+ + V V+++
Sbjct: 219 LPELAASIMASLKGHGDMALGNVIGSCIFN-LLAIMGITSMIETIDAMGINKVDLGVMLF 277
Query: 176 MVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
++ +++L ++ E ++Y Y V +F
Sbjct: 278 LM-VALLPVLWTQKKLSRLEGAFFLLIYCGYTVYLF 312
Score = 34.3 bits (75), Expect = 6.1
Identities = 17/61 (27%), Positives = 31/61 (50%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
V+G+T +AFG PE + G I + N +G+N I L + L++ ++++
Sbjct: 39 VVGLTVVAFGTSAPELAVCIKATLNGMDDIALGNVIGSNICNIGLVLAIAALLKPIAVQS 98
Query: 346 Q 346
Q
Sbjct: 99 Q 99
>UniRef50_UPI000155609B Cluster: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger NCKX1; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
potassium-dependent sodium-calcium exchanger NCKX1 -
Ornithorhynchus anatinus
Length = 543
Score = 59.7 bits (138), Expect = 1e-07
Identities = 35/132 (26%), Positives = 67/132 (50%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG++ LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 407 GETIGISEEIMGLSILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 466
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
+ ++ G AV +S G+ + K+ + + +G + +L
Sbjct: 467 FLYSL---FNGLRPVAV--SSNGLFCAIVLLFLMLLFVITSIASCKWKMNKLLGFTMFVL 521
Query: 397 YVVFIVFAILVE 408
Y VF+V ++++E
Sbjct: 522 YFVFLVISVMLE 533
Score = 48.0 bits (109), Expect = 5e-04
Identities = 31/103 (30%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 167 PVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFN-SMKAFV--LIDK 222
P+ RDV Y++++ +L+AF DG + W+E+++L Y LY F + +N ++A+V + +
Sbjct: 158 PLFRDVSFYILDLLMLIAFFSDGTVAWWESLLLLAAYALYVFAMKWNRPLEAWVKGRVGR 217
Query: 223 IWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTT 265
AA G + + V+V E DN PS + G++
Sbjct: 218 RTAAASVPAAGDAPQVGSSAVAVNEPEDNGKLKLPSLLVRGSS 260
Score = 46.4 bits (105), Expect = 0.001
Identities = 20/50 (40%), Positives = 33/50 (66%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLK 99
+P+ +F+ E+ R+G LL+V Y F LAIVC++YF+P + +I L+
Sbjct: 88 YPEDVFSVEERRRGWVLLHVSGMAYVFVALAIVCDEYFVPALGVITAKLE 137
>UniRef50_Q1F081 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Clostridium oremlandii OhILAs|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Clostridium oremlandii OhILAs
Length = 310
Score = 59.7 bits (138), Expect = 1e-07
Identities = 62/275 (22%), Positives = 114/275 (41%), Gaps = 21/275 (7%)
Query: 69 VVFGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF 127
+ F + + LAI+ + D+ I + L I + T ++ TS PE VN+I++F
Sbjct: 4 IPFIVLIVSFLAIIKSADWLIDASSALALYLGISPLIVGLTVVAFGTSAPEASVNIIASF 63
Query: 128 LTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVW 187
+S++ IG I GS + N I D + D+ ++ + + V
Sbjct: 64 QKKSEIVIGNITGSNIINIGIVIGITSLIYT--IKADWSVIRVDIPFAFISSAAFILLVV 121
Query: 188 DGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
DG + + ++L IL +Y ++ + K + KK N LN ++ +
Sbjct: 122 DG-LSNKDGLILAILLFIYLNYLWLTSK----------SSRKKGN----DLNRQSMDLIH 166
Query: 248 GIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIM 307
+ V +G + + K ++ +G+T +AFG LPE + +
Sbjct: 167 ILFYLVLGIIGLVISGYYIVDASV---KIATLLGFSQAFIGLTVVAFGTSLPELITCLVA 223
Query: 308 SRRGEGGIGVSNALGANSLAILFALGLPWLIRTVS 342
+ I V N +G+N ILF L + LI ++
Sbjct: 224 CHKKNDDIAVGNIIGSNIFNILFVLSVSSLISPIA 258
Score = 49.2 bits (112), Expect = 2e-04
Identities = 32/151 (21%), Positives = 61/151 (40%), Gaps = 2/151 (1%)
Query: 61 RQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFF 120
RQ L++++F + + ++ Y + I L Q T ++ TS PE
Sbjct: 159 RQSMDLIHILFYLVLGIIGLVISGYYIVDASVKIATLLGFSQAFIGLTVVAFGTSLPELI 218
Query: 121 VNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNIS 180
+++ D+ +G I+GS +FN +PIA + + +
Sbjct: 219 TCLVACHKKNDDIAVGNIIGSNIFN--ILFVLSVSSLISPIAFSSHLIIDLAFMLLFTFL 276
Query: 181 VLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
+ + +I E VL +LY+ YFV ++
Sbjct: 277 LFIFSYTHKKISRLEGFVLMMLYLFYFVFIY 307
Score = 36.7 bits (81), Expect = 1.1
Identities = 19/59 (32%), Positives = 32/59 (54%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
++G+T +AFG PEA I S + + I + N G+N + I +G+ LI T+ +
Sbjct: 40 IVGLTVVAFGTSAPEASVNIIASFQKKSEIVIGNITGSNIINIGIVIGITSLIYTIKAD 98
>UniRef50_A5USC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=21;
Bacteria|Rep: Na+/Ca+ antiporter, CaCA family -
Roseiflexus sp. RS-1
Length = 367
Score = 59.7 bits (138), Expect = 1e-07
Identities = 62/257 (24%), Positives = 105/257 (40%), Gaps = 20/257 (7%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFL--TESDMGIGTIVGSALFNXXXXXXXXXX 155
L I V T ++ TS PE V++ S +D+ +G +VGS + N
Sbjct: 34 LGISPLVVGLTVVAFGTSAPELAVSIQSALSGPNGADVALGNVVGSNIANVLLILGISAA 93
Query: 156 XXXTPIAIDMRPVTRDVLIYMVNISVLV-AFVWDGQIDWFEAMVLGILYILYFVVMFNSM 214
TP+ + + + DV + M+ ISV+V DG I + ++L I Y V
Sbjct: 94 I--TPLVVQQQLIRLDVPL-MIGISVVVFVMALDGTISRIDGLILFAGIIAYTVFAIRQS 150
Query: 215 KAFVLIDKIWAACCKKNNGVTASLNDNNV-SVEEGIDNKGF--NDPSPVTNGTTMTEKPA 271
+ + A + N S+ + + N F + + G+ A
Sbjct: 151 RQ---------ESAEVQEEYHAEFDANRPQSIGDWLKNVAFLIGGLALLVVGSRWMVDGA 201
Query: 272 IDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFA 331
+ F + E V+G+T +A G LPE + + + RGE I V N +G+N +L
Sbjct: 202 VSF--ARVFGVSELVIGLTIVAVGTSLPEIATSIVAALRGERDIAVGNVVGSNIFNLLSV 259
Query: 332 LGLPWLIRTVSLEIQGA 348
LGL ++ + + A
Sbjct: 260 LGLSSVVAPAGISVAPA 276
Score = 41.9 bits (94), Expect = 0.031
Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 5/151 (3%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
G +L V F I LL +V + + + + + V T ++V TS PE +
Sbjct: 174 GDWLKNVAFLIGGLALL-VVGSRWMVDGAVSFARVFGVSELVIGLTIVAVGTSLPEIATS 232
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
+++ E D+ +G +VGS +FN I++ + D+ + +
Sbjct: 233 IVAALRGERDIAVGNVVGSNIFNLLSVLGLSSVVAPAGISVAPAALNFDMPVMLAVAVAC 292
Query: 183 VAFVWDGQI--DWFEAMVLG--ILYILYFVV 209
+ + G++ W + LG I Y LY ++
Sbjct: 293 LPIFFTGRLIARWEGWLFLGYYIAYTLYLIL 323
>UniRef50_A0BTS9 Cluster: Chromosome undetermined scaffold_128,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_128,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 378
Score = 59.7 bits (138), Expect = 1e-07
Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)
Query: 74 YTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES-D 132
Y + + NDY +PC+E + + + M++ S PE N++S F +
Sbjct: 10 YVLSGQTYLSNDYLMPCLESLSTKWHLSET-GTGILMALGMSIPELTTNILSCFKSSRIG 68
Query: 133 MGIGTIVGSALFNXXX----XXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
G G IVGS +F+ + ++++ + RD+ +Y++ + L WD
Sbjct: 69 YGFGAIVGSGVFDFTVCFGLMSLFSNYYHKRALRMNLKALMRDIYVYLLTLLFLTFVFWD 128
Query: 189 GQIDWFEAMVLGIL---YILYFVVMFNSMKAFVL 219
+I EA++L + Y+LY +V F L
Sbjct: 129 YEISLTEALILTLFYPSYLLYSLVQMEQKDDFQL 162
>UniRef50_P87122 Cluster: Sodium/calcium exchanger; n=1;
Schizosaccharomyces pombe|Rep: Sodium/calcium exchanger
- Schizosaccharomyces pombe (Fission yeast)
Length = 743
Score = 59.7 bits (138), Expect = 1e-07
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 56 TDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATS 115
T LR + V + I+ F + I +D+F + I L++P +V TF+++
Sbjct: 103 TINSLRFPVLSIIVGWLIFLFITIGISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNG 162
Query: 116 CPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIY 175
P+ + + M IG ++GSA F P I R RDV
Sbjct: 163 SPDILSTFAAVRVNSGGMAIGELLGSAFF--IVAIVAGSVCLIKPFKIPRRHFLRDVAFL 220
Query: 176 MVNISVLVAFV-WDGQIDWFEAMVLGILYILYFVVMFNS 213
I +++ FV DG + ++++V+ + Y+LY + +F S
Sbjct: 221 TGTILLVIMFVLHDGSLSIWQSLVMILYYLLYVLFVFFS 259
Score = 45.2 bits (102), Expect = 0.003
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 4/133 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G F + ES++G+T A G L + + +++R G + + G +L IL +G+
Sbjct: 611 GVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPEMAMGGVFGGPTLNILIGIGISS 670
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++S N +V+ + I + + +F + R +G++L IL
Sbjct: 671 FYSSIS----NHGNDSVIEIPHSLSITAYFLLACLLLLLIYVPLNRFRVNRVLGLLLFIL 726
Query: 397 YVVFIVFAILVEL 409
Y+V I+VEL
Sbjct: 727 YIVGTSTNIVVEL 739
Score = 41.5 bits (93), Expect = 0.040
Identities = 20/58 (34%), Positives = 30/58 (51%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
+P+SV+G+TFLA G P+ S F R GG+ + LG+ + G LI+
Sbjct: 147 LPDSVVGVTFLALGNGSPDILSTFAAVRVNSGGMAIGELLGSAFFIVAIVAGSVCLIK 204
>UniRef50_Q6J4K2 Cluster: Sodium/potassium/calcium exchanger 6
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6); n=30;
Euteleostomi|Rep: Sodium/potassium/calcium exchanger 6
precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) - Homo
sapiens (Human)
Length = 584
Score = 59.3 bits (137), Expect = 2e-07
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A LYV + +Y F +L + +F P + I LK+ NVA TF++ P+ F
Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIF--- 155
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT---PIAIDMRPVTRDVLIYMVNIS 180
S + SD + ALF T P RP RD++ YMV +
Sbjct: 156 -SALVAFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVF 214
Query: 181 VLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ ++ G++ A+ LY+ Y V +
Sbjct: 215 LTFLMLFRGRVTLAWALGYLGLYVFYVVTV 244
Score = 47.2 bits (107), Expect = 8e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE I G F + +V+G+T LA+G + +A S F ++R+G + S G
Sbjct: 438 TEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIF 497
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK--FT 384
IL +GL L++ +T V + G+ + ++ + F
Sbjct: 498 NILVGVGLGCLLQI------SRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQ 551
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGII 412
L R G L + Y+ F+V A+L E G+I
Sbjct: 552 LSRVYGFCLLLFYLNFLVVALLTEFGVI 579
>UniRef50_Q8W102 Cluster: AT5g17860/MVA3_210; n=2; Arabidopsis
thaliana|Rep: AT5g17860/MVA3_210 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 570
Score = 58.8 bits (136), Expect = 2e-07
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 2/133 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS-TFLTESDMG 134
F LL YF P ++ + + LK+ +A T +S+ P+ F +V+S T D G
Sbjct: 113 FYLLGDTAASYFCPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSSVVSFTRSNNGDFG 172
Query: 135 IGTIVGSALF-NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDW 193
+ +I+G A F + +AID RDV+ +V + L ++ G++
Sbjct: 173 LNSILGGAFFVSSFVVGTICVLIGSRDVAIDRNSFIRDVVFLLVALCCLGLIIFIGKVTI 232
Query: 194 FEAMVLGILYILY 206
+ A+ +Y+LY
Sbjct: 233 WVALCYLSIYLLY 245
>UniRef50_A6LNC0 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
Thermotogaceae|Rep: Na+/Ca+ antiporter, CaCA family -
Thermosipho melanesiensis BI429
Length = 311
Score = 58.4 bits (135), Expect = 3e-07
Identities = 60/292 (20%), Positives = 119/292 (40%), Gaps = 21/292 (7%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+ + G+ +L + D+ + I +L + + V + ++ TS PE +++S
Sbjct: 1 MFLTLLGLIVGFVLLVKGADWLVDGATSIALNLGVSKIVVGLSVVAFGTSLPELVASLVS 60
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL-VA 184
S + I +VGS + N I I + ++ +++ V V
Sbjct: 61 VIKGHSSVSISNVVGSNIANIAIALALSSLFVS--INIKKNTIKAEMPFMIISTIVFTVL 118
Query: 185 FVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVS 244
F+ D + W +V L ++Y + S K ++++ + K + L
Sbjct: 119 FIKDNSLTWNYGVVFISLLVIYLYYLITSAKN--VVEEEFKDEVKYKTHIALLL------ 170
Query: 245 VEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSI 304
+ GI G +T G + K + + E+ +G+T +A G LPE
Sbjct: 171 IVVGI--VGIWLGGDLTIGNVI--------KLAKSLGLSETFVGLTIVAIGTSLPEIVVS 220
Query: 305 FIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLIN 356
I + + E I V N +G+N ILF LG+ L+ + +++Q +++N
Sbjct: 221 IISTLKNEADILVGNIVGSNIFNILFILGVSSLVGNLYVDVQNFTIDLIIMN 272
Score = 48.8 bits (111), Expect = 3e-04
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 55 FTDE-QLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVA 113
F DE + + LL +V GI L D I V + + L + + T +++
Sbjct: 156 FKDEVKYKTHIALLLIVVGIVGIWL----GGDLTIGNVIKLAKSLGLSETFVGLTIVAIG 211
Query: 114 TSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVL 173
TS PE V++IST E+D+ +G IVGS +FN + +D++ T D++
Sbjct: 212 TSLPEIVVSIISTLKNEADILVGNIVGSNIFNILFILGVSSLVGN--LYVDVQNFTIDLI 269
Query: 174 IYMVNISVLVAF 185
I +N+ V + F
Sbjct: 270 I--MNLFVFILF 279
>UniRef50_A7HL13 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Na+/Ca+
antiporter, CaCA family - Fervidobacterium nodosum
Rt17-B1
Length = 314
Score = 58.0 bits (134), Expect = 4e-07
Identities = 53/276 (19%), Positives = 116/276 (42%), Gaps = 15/276 (5%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L ++ I F ++I +D + + + LK+ + T ++ TS PE VN++S
Sbjct: 2 ILSILLLIIGFVFVSIG-SDKLVEGASTLAKKLKVSDLLIGLTIVAFGTSAPELAVNIVS 60
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ S++ +G ++GS +FN P+ + + +++ + + I+ L
Sbjct: 61 SIKGTSNISLGNVIGSNIFN--ILVVVGLSAVIRPVIVQHSTLRKEIPLSL--IAALSIL 116
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSV 245
+ GI+ +L+F + + + D+ +K + + +
Sbjct: 117 ALGNKTPSVITRGDGIVLLLFFAIFMSYILEMAQKDREMFEELEKTKEKQLGTIISILYI 176
Query: 246 EEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIF 305
G+ F + NG A+D F + + ++G+T +A G +PE +
Sbjct: 177 IGGLAGLVFGG-RWIVNG-------AVD--IAKAFGVSDKLIGLTIVAAGTSIPELATSL 226
Query: 306 IMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+G I + NA+G+N + F LG+ +I+ +
Sbjct: 227 AAIIKGNNEIALGNAVGSNIFNVFFILGISAVIKPI 262
Score = 42.7 bits (96), Expect = 0.017
Identities = 20/63 (31%), Positives = 35/63 (55%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ + ++G+T +AFG PE + S +G I + N +G+N IL +GL +IR V
Sbjct: 35 VSDLLIGLTIVAFGTSAPELAVNIVSSIKGTSNISLGNVIGSNIFNILVVVGLSAVIRPV 94
Query: 342 SLE 344
++
Sbjct: 95 IVQ 97
Score = 33.9 bits (74), Expect = 8.1
Identities = 23/117 (19%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I + + + T ++ TS PE ++ + +++ +G VGS +FN
Sbjct: 197 IAKAFGVSDKLIGLTIVAAGTSIPELATSLAAIIKGNNEIALGNAVGSNIFN--VFFILG 254
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
PI + + DV + ++ +L+ F + +I+ FE +++ Y+ Y + +
Sbjct: 255 ISAVIKPI-VYTTVLNFDVTLLVIITVILLLFSKNLKIEKFEGLLMVSTYVGYTIYL 310
>UniRef50_Q5KN42 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 974
Score = 58.0 bits (134), Expect = 4e-07
Identities = 36/181 (19%), Positives = 82/181 (45%), Gaps = 11/181 (6%)
Query: 65 FLLYVVFGI-YTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
F+L+++F + + F+ + I D+F P + + L + ++ A TF++ P+ F
Sbjct: 78 FILFLLFILAFLFSFIGISAADFFCPNLSTVAAYLGLNESTAGVTFLAFGNGSPDVFSTF 137
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ + +G ++G+A F P + RDV+ + + + +L+
Sbjct: 138 SAMSSGTLGLAVGELIGAASF--IVSIVVGSIAFIRPFHVPKNAFRRDVIFFTIAVLMLI 195
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNV 243
+ DG + + E+ + LY++Y V V+ + W ++ +G+ L+ N++
Sbjct: 196 VALHDGHLTFAESGSMVGLYVVYVGV--------VVSESWWMRRIRRRHGLKHKLSSNSI 247
Query: 244 S 244
S
Sbjct: 248 S 248
Score = 38.3 bits (85), Expect = 0.38
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES G+TFLAFG P+ S F G G+ V +GA S + +G IR
Sbjct: 116 ESTAGVTFLAFGNGSPDVFSTFSAMSSGTLGLAVGELIGAASFIVSIVVGSIAFIR 171
>UniRef50_Q310J5 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein precursor; n=4; Proteobacteria|Rep:
K+-dependent Na+/Ca+ exchanger related-protein precursor
- Desulfovibrio desulfuricans (strain G20)
Length = 322
Score = 57.6 bits (133), Expect = 6e-07
Identities = 58/277 (20%), Positives = 115/277 (41%), Gaps = 21/277 (7%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
V+FG+ L + D F+ +P + + TS PE V+ ++
Sbjct: 8 VIFGL----ALLVWSADRFVEGSASTARHFGMPPLLIGMVIVGFGTSAPEMVVSALAASQ 63
Query: 129 TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
+ +G GS + N +PIA+ + + +++ I V ++ +WD
Sbjct: 64 GNPGIALGNAYGSNITNIALILGVTALI--SPIAVHSQVLRKELPILTVVTALAAWQLWD 121
Query: 189 GQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEG 248
G+I +A+VL + +F + A+ IW KK + + + + + + V
Sbjct: 122 GKITRLDAIVL--------LTVFGGLMAWT----IWQGMQKKADALGSEM-EQELDVRAM 168
Query: 249 IDNKGFNDPSPVTNGTTMTEKPAI--DEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFI 306
+ S ++ + + + H F + + ++G+T +A G LPE S I
Sbjct: 169 PIRRAVFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSII 228
Query: 307 MSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+R+GE I + N LG+N L +G+ I +++
Sbjct: 229 ATRKGEHDIALGNVLGSNLFNTLAVVGIAGAIHPMAI 265
Score = 46.8 bits (106), Expect = 0.001
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 6/151 (3%)
Query: 70 VFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
VF + +L +V + + I + + T ++V TS PE ++I+T
Sbjct: 174 VFWLSVGLVLLVVSSRILVWGAVEIAHGFGVSDLIIGLTIVAVGTSLPELASSIIATRKG 233
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYM-VNISVLV---AF 185
E D+ +G ++GS LFN P+AI RD+++ + +S+ V F
Sbjct: 234 EHDIALGNVLGSNLFNTLAVVGIAGAIH--PMAIGPEVFNRDMMVMAGLTLSLFVFGYGF 291
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKA 216
G+I+ E VL Y+ Y + ++ A
Sbjct: 292 RGPGRINRLEGAVLLACYVGYTAYLITTILA 322
Score = 40.7 bits (91), Expect = 0.071
Identities = 21/67 (31%), Positives = 34/67 (50%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F +P ++GM + FG PE + + +G GI + NA G+N I LG+ LI
Sbjct: 33 FGMPPLLIGMVIVGFGTSAPEMVVSALAASQGNPGIALGNAYGSNITNIALILGVTALIS 92
Query: 340 TVSLEIQ 346
+++ Q
Sbjct: 93 PIAVHSQ 99
>UniRef50_Q1PZ72 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 318
Score = 57.6 bits (133), Expect = 6e-07
Identities = 71/306 (23%), Positives = 128/306 (41%), Gaps = 30/306 (9%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L I + T ++ TS PE +IS +D+ IG ++GS + N
Sbjct: 34 LNIKPIIIGLTIIAFGTSAPELVTGIISGIRNLNDIAIGNVIGSNIANVGLVLGVTAIIL 93
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKA- 216
P+ ++M + R++ I + +L +G + +E +L + ++Y + S K
Sbjct: 94 --PLKVEMNLLRREIPIIIGISGLLYLMCRNGILSRWEGGLLVVGIVVYTCYISRSAKKE 151
Query: 217 FVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKN 276
+I++ +A K N T SL+ + + G+ + + G + AI
Sbjct: 152 SKVIEEEFADFISKKN--TLSLDILFMFI--GL--------TTLIGGAHLLVNSAI--YL 197
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
F I E V+G++ +A G LPE + + R E I V N LG+N IL LG+
Sbjct: 198 ARNFGISELVVGLSVVAVGTSLPELAISTVAAFRKESDICVGNVLGSNIYNILAVLGITA 257
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
+I + IN++ + F I + + KF L R G+ L +
Sbjct: 258 IIHPLQ------------INTSSLQFDMPVMIVFSLLL-IPMIMRKFILTRWEGVFLLVG 304
Query: 397 YVVFIV 402
Y+ +++
Sbjct: 305 YIFYMI 310
Score = 42.7 bits (96), Expect = 0.017
Identities = 26/119 (21%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ + I + V + ++V TS PE ++ ++ F ESD+ +G ++GS ++N
Sbjct: 197 LARNFGISELVVGLSVVAVGTSLPELAISTVAAFRKESDICVGNVLGSNIYNILAVLGIT 256
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQI-DWFEAMVLGILYILYFVVMF 211
P+ I+ + D+ + +V +L+ + I +E + L + YI Y + ++
Sbjct: 257 AIIH--PLQINTSSLQFDMPVMIVFSLLLIPMIMRKFILTRWEGVFLLVGYIFYMIAIY 313
>UniRef50_Q8EJV2 Cluster: Sodium/calcium exchanger; n=6;
Bacteria|Rep: Sodium/calcium exchanger - Shewanella
oneidensis
Length = 316
Score = 57.2 bits (132), Expect = 8e-07
Identities = 56/245 (22%), Positives = 102/245 (41%), Gaps = 18/245 (7%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L I V T ++ TS PE V+V + S + +G ++GS + N
Sbjct: 32 LGITPLVIGLTIVAFGTSAPELAVSVKAALAGNSGIALGNVIGSNIVNIGLILGITALIR 91
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAF 217
PI + V RD+ I ++ + + DG++ + ++L + Y V + S K
Sbjct: 92 --PIEVKSEMVKRDIPIMILASMLFWGLLLDGELSLIDGVILLSFMLGYLVFSYFSAKNT 149
Query: 218 VLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNG 277
D KN ++ + + GI S + G + A+D
Sbjct: 150 NDADGEVIEEGPKNPLLSL------LFIAVGI--------SMLVGGGILFVNGAVDLAK- 194
Query: 278 HTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWL 337
F + E ++G+T +A G +PE + + + +G+ I + N +G+N IL LG+ +
Sbjct: 195 -VFGVSEIIIGLTIVAIGTSMPELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAI 253
Query: 338 IRTVS 342
+ VS
Sbjct: 254 VYPVS 258
Score = 46.4 bits (105), Expect = 0.001
Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 4/114 (3%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ + + T +++ TS PE +V++ +SD+ IG IVGS +FN
Sbjct: 198 VSEIIIGLTIVAIGTSMPELVTSVLAALKGQSDIAIGNIVGSNIFNILGILGVTAIVY-- 255
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDG-QIDWFEAMVLGILYILYFVVMFN 212
P++ + + D ++ + V++ F W G +I E L I Y+ Y + + N
Sbjct: 256 PVS-GLGFQSLDFIVMLAFAVVILPFAWTGLRIGRREGATLLIAYLGYLIYLVN 308
Score = 40.3 bits (90), Expect = 0.093
Identities = 20/59 (33%), Positives = 32/59 (54%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
V+G+T +AFG PE + G GI + N +G+N + I LG+ LIR + ++
Sbjct: 38 VIGLTIVAFGTSAPELAVSVKAALAGNSGIALGNVIGSNIVNIGLILGITALIRPIEVK 96
>UniRef50_A0EC62 Cluster: Chromosome undetermined scaffold_89, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_89,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 553
Score = 57.2 bits (132), Expect = 8e-07
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 8/147 (5%)
Query: 71 FGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTE 130
F F LL+ +Y P V I + K+ Q ++ T +++A P+ +I+T E
Sbjct: 62 FFFVMFNLLSKTAENYLSPAVAHIAKYFKLSQTLSGITLIALANGAPDVITAIIAT--GE 119
Query: 131 SDMGI----GTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
D G+ G+I GS LF I ++ +TRD++ ++ I ++ F
Sbjct: 120 DDQGVLIAVGSIFGSGLF-MTTFVLGSVLYYSKHILVNKVSLTRDLIFNILGIGSIITFG 178
Query: 187 WDGQIDWFEAMVLGILYILY-FVVMFN 212
+ G I +++ LYI+Y FVVM N
Sbjct: 179 YIGYISNQFSILFVSLYIMYIFVVMLN 205
>UniRef50_A5IG18 Cluster: Na/Ca antiporter; n=5; Legionella
pneumophila|Rep: Na/Ca antiporter - Legionella
pneumophila (strain Corby)
Length = 319
Score = 56.8 bits (131), Expect = 1e-06
Identities = 53/238 (22%), Positives = 102/238 (42%), Gaps = 17/238 (7%)
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAID-MR 166
T +++ TS PE F+++IS+ ++D+ IG +GS + N T + ++
Sbjct: 42 TIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANIGLILGIIILIKPTSFHFNKLK 101
Query: 167 PVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFN-SMKAFVLIDKIWA 225
V ++I M+ L+ + G ID ++ I + YF+ + + S K + +++
Sbjct: 102 KVYPILIIVMLFAYSLILDGYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFRP 161
Query: 226 ACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPES 285
A S N +S+ G+ V N + + + I E
Sbjct: 162 AILSYR-----STPSNLLSIAIGLLILPICSKYLVYNASEIAKWAGISE----------F 206
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+G+T +A G LPE + + + +GE I + +G+N +L L LP L+ +
Sbjct: 207 TIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGTIIGSNIYNLLLILALPGLLNPTKI 264
Score = 42.3 bits (95), Expect = 0.023
Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
L+ +C+ Y + I + I + T +++ +S PE ++++ E + IGT
Sbjct: 181 LILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT 240
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
I+GS ++N P I + RD+ + M++I++L+ F+ +
Sbjct: 241 IIGSNIYN--LLLILALPGLLNPTKISSVVLWRDMPV-MLSITLLLLFLNYYYQKKTSSW 297
Query: 198 VLGILYILYFVVM 210
GIL ++YF M
Sbjct: 298 PGGILLLVYFCYM 310
Score = 35.1 bits (77), Expect = 3.5
Identities = 19/63 (30%), Positives = 32/63 (50%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + ++G+T +A G PE I S + + + + NA+G+N I LG+ LI+
Sbjct: 32 FQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANIGLILGIIILIK 91
Query: 340 TVS 342
S
Sbjct: 92 PTS 94
>UniRef50_Q0UXS4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 996
Score = 56.8 bits (131), Expect = 1e-06
Identities = 34/152 (22%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
AF++ ++ F+ + I +D+F + I L + +++A T ++ P+ F +
Sbjct: 108 AFVIMTLWLAMLFSTIGIAASDFFCVNLNTIARMLGMSESLAGVTLLAFGNGSPDVF-ST 166
Query: 124 ISTFLTES-DMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
+ F T + + +G ++G+A F P A+ + RDV ++V +
Sbjct: 167 FAAFRTHAASLAVGELIGAACF--ITAVVSGSMALIRPFAVARKSFIRDVGFFLVAAAFS 224
Query: 183 VAFVWDGQIDWFEAMVLGILYILY--FVVMFN 212
+ F+ DG++ +E++ + YI Y FVV ++
Sbjct: 225 MGFIIDGKLHLWESLAMVAFYIFYVAFVVAWH 256
>UniRef50_A4RK23 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1004
Score = 56.4 bits (130), Expect = 1e-06
Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
AF L + FT + I +D+F + I L + +++A TF++ P+ F
Sbjct: 100 AFGLLAAWLALLFTTIGIAASDFFSINLSTIASILGLSESLAGVTFLAFGNGSPDVFSTF 159
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ M +G ++G+A F + R RD+ +++ S +
Sbjct: 160 AAMGSNSGSMAVGELIGAAGF--ITAVVAGSMALVREFKVVKRTFVRDICFFILAASFAM 217
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
A + DG + ++E +++ YI Y +V+
Sbjct: 218 AVLADGHLHFWECIIMVAFYIFYVMVV 244
Score = 35.9 bits (79), Expect = 2.0
Identities = 19/58 (32%), Positives = 26/58 (44%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
+ ES+ G+TFLAFG P+ S F G + V +GA G L+R
Sbjct: 136 LSESLAGVTFLAFGNGSPDVFSTFAAMGSNSGSMAVGELIGAAGFITAVVAGSMALVR 193
>UniRef50_Q57556 Cluster: Uncharacterized membrane protein MJ0091;
n=9; Methanococcales|Rep: Uncharacterized membrane
protein MJ0091 - Methanococcus jannaschii
Length = 302
Score = 56.4 bits (130), Expect = 1e-06
Identities = 61/273 (22%), Positives = 118/273 (43%), Gaps = 34/273 (12%)
Query: 69 VVFGIYTFTLLAIVC---NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
++ G+ F L I+ +D+F+ E I + V AT M++ TS PE + +
Sbjct: 2 LILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYA 61
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+++ + IG +GS + N +PI +D + + +++L+Y++ +
Sbjct: 62 SYMHAPGISIGNAIGSCICNIGLVLGLSAII--SPIIVD-KNLQKNILVYLLFVIFAAVI 118
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSV 245
DG W + +VL ++ F++ W NG +A + +NN
Sbjct: 119 GIDG-FSWIDGVVL----LILFIIYLR-----------WTV----KNG-SAEIEENN--- 154
Query: 246 EEGIDNKGFNDPSPVTN--GTTMTEKPAID--EKNGHTFFIPESVMGMTFLAFGGCLPEA 301
++ + F+ + G + + +D +K I + V+G T +AFG LPE
Sbjct: 155 DKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPEL 214
Query: 302 CSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
++R GG+ + N +G+N I AL +
Sbjct: 215 MVSLAAAKRNLGGMVLGNVIGSNIADIGGALAV 247
Score = 35.1 bits (77), Expect = 3.5
Identities = 23/82 (28%), Positives = 37/82 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
E+ F + V+G T +A G LPE + S GI + NA+G+ I LG
Sbjct: 28 ERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLG 87
Query: 334 LPWLIRTVSLEIQGAENTAVLI 355
L +I + ++ +N V +
Sbjct: 88 LSAIISPIIVDKNLQKNILVYL 109
>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
exchanger protein - Tetrahymena thermophila SB210
Length = 5392
Score = 56.0 bits (129), Expect = 2e-06
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 14/181 (7%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L +V + F LL+ Y P + I + LK Q +A T +++ P+ F +I+
Sbjct: 4839 ILTIVISLVAFHLLSSTAESYLSPALAKISDSLKCSQTLAGVTLLALGNGAPDVFTAIIA 4898
Query: 126 TFLTESD---MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
+ + + IG+I G+ LF + D RDV Y ++
Sbjct: 4899 GGGNDDEGINLAIGSIFGAGLF-VTTVTLAKVIKNSDELKADKNIFIRDVGFYCFAAFLI 4957
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASL-NDN 241
+ ++ G++++ A+ LY ++ + V+I + W A K+ NG+ A L +D
Sbjct: 4958 LIYLLIGKVNFPMAVAFFSLYFVFII---------VVIYQEWDAKRKRKNGINAQLISDE 5008
Query: 242 N 242
N
Sbjct: 5009 N 5009
>UniRef50_Q31H01 Cluster: Ca2+:cation antiporter (CaCA) family
transporter precursor; n=1; Thiomicrospira crunogena
XCL-2|Rep: Ca2+:cation antiporter (CaCA) family
transporter precursor - Thiomicrospira crunogena (strain
XCL-2)
Length = 329
Score = 56.0 bits (129), Expect = 2e-06
Identities = 54/274 (19%), Positives = 107/274 (39%), Gaps = 13/274 (4%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L+ + ++ L + +D FI + I + + TS PE V +++
Sbjct: 5 LILPLIVLFVGLALLVWSSDIFIEGAASTAIHMNISPLIIGVVVLGFGTSAPEILVAILA 64
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ + IG +VGS + N +P+ I + R+ I + V +
Sbjct: 65 SIDNSPGLAIGNVVGSNIANIGLVLGVTAII--SPVVIKSSLLKREFPILLGISLVGILL 122
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNN-VS 244
+ D +D + ++L L ++ M + K D + ++ + N V
Sbjct: 123 MLDKDLDITDGIILLALLLIVMTWMIRANKNISPSDPLAEETIEEIEDLPKLSNQKALVF 182
Query: 245 VEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSI 304
+ G+ + V + E F +PE ++G+T +A G LPE +
Sbjct: 183 LILGLVVLMISAKMMVWGAVEIAE----------FFDVPEMIIGLTIVAIGTSLPELAAA 232
Query: 305 FIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+++GE + + N LG+N +L + +P LI
Sbjct: 233 ITAAKKGEADLMIGNILGSNLFNLLAVMSMPALI 266
Score = 43.2 bits (97), Expect = 0.013
Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Query: 69 VVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
+VF I +L I VE I E +P+ + T +++ TS PE + +
Sbjct: 180 LVFLILGLVVLMISAKMMVWGAVE-IAEFFDVPEMIIGLTIVAIGTSLPELAAAITAAKK 238
Query: 129 TESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRD--VLIYMVNISVLVAFV 186
E+D+ IG I+GS LFN P ID + D +++ + +LVA
Sbjct: 239 GEADLMIGNILGSNLFN--LLAVMSMPALIAPSVIDNATLLLDYPIMLALTLAMLLVALP 296
Query: 187 WDGQ--IDWFEAMVLGILYILYFVVMF 211
G+ I E +L I +I Y ++++
Sbjct: 297 RKGKAVITKTEGYILLISFIGYMLLLY 323
>UniRef50_A3UFQ1 Cluster: Sodium/calcium exchanger; n=2;
Hyphomonadaceae|Rep: Sodium/calcium exchanger -
Oceanicaulis alexandrii HTCC2633
Length = 334
Score = 56.0 bits (129), Expect = 2e-06
Identities = 74/347 (21%), Positives = 134/347 (38%), Gaps = 32/347 (9%)
Query: 65 FLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI 124
F L V+ GI ++ + D + + +P + T ++ TS PE V+
Sbjct: 7 FSLMVLGGI----VVLLTGGDILVRGATALASKAGVPPLLVGLTIVAFGTSAPEMVVSAA 62
Query: 125 STFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVA 184
+ + IG IVGS + N PIA V R+ I + ++ +A
Sbjct: 63 AAVEGAPGLAIGNIVGSNIANVLLVLGLPALLA--PIASTATGVKRNAFIALGFTALFIA 120
Query: 185 FVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVS 244
DG + + +L + + Y + + KA ++ + A L D +
Sbjct: 121 LCLDGALSLMDGAILAVGIVGYVSFLALTAKAHA------------DDPMIAELTD--IE 166
Query: 245 VEEGIDNKGFNDPSPVTNGTTMTEKPA---IDEKNGHT--FFIPESVMGMTFLAFGGCLP 299
+G+ K + G M A +D G F +P++V+G+T LAFG LP
Sbjct: 167 HMDGLPAKAPMVALFLLGGLVMLPIGAQLIVDGGVGIAALFNVPDAVIGLTILAFGTSLP 226
Query: 300 EACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAG 359
E + + + R + + + N +G+N I G+ L + + + V
Sbjct: 227 ELATALVAALRKQADMAIGNVVGSNIFNISAVGGITGLAASFAT----GQPAPVSDQFIQ 282
Query: 360 IDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFIVFAIL 406
+DF + LF + + R G+V+ + YV +I +L
Sbjct: 283 LDFWVMTAAALAILAF-ALF--RRPIGRVSGLVMTLAYVSYIALLVL 326
>UniRef50_A1Z7I1 Cluster: CG14744-PA; n=2; Sophophora|Rep:
CG14744-PA - Drosophila melanogaster (Fruit fly)
Length = 513
Score = 56.0 bits (129), Expect = 2e-06
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 4/162 (2%)
Query: 253 GFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE 312
G + S VT +TE + E G F + ES M +TF A P+ + + ++ +G
Sbjct: 346 GVHQNSMVTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGY 405
Query: 313 GGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXX 372
G + + +G AIL ++ L ++ E+ GA N+ V + +
Sbjct: 406 GRMAFAAIIGGPVFAILVSMSLAFIFNHRVREV-GA-NSWVYGDLGDNCYLFLVITIVTT 463
Query: 373 XXWIVLFIGKFTLRRTVGIVLGILYVVFIVFAILVELGIIFD 414
W V F F RR+ G+ L ++Y+ F+++A+ VE ++ +
Sbjct: 464 MWWSVTF--DFHARRSAGVFLWLVYLQFLLYAVCVEWDVVHE 503
Score = 46.4 bits (105), Expect = 0.001
Identities = 36/156 (23%), Positives = 69/156 (44%), Gaps = 8/156 (5%)
Query: 57 DEQLRQGAFLLYVVFGIYTFT-LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATS 115
D++ + F+L F F L++ YF P +++I L + + +A TF++
Sbjct: 9 DDKATEVLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNC 68
Query: 116 CPEFFVNVISTFLTESDMGIGTI-VGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLI 174
PE N++ +D I TI VG+ L P ++ RD+L
Sbjct: 69 SPEIIANLMP---VRADAPIFTITVGNTL--AIILLSGGTVCFLRPFRMNGHSTLRDLLF 123
Query: 175 YMVNISVL-VAFVWDGQIDWFEAMVLGILYILYFVV 209
++ + VL + +G + E +VL ++Y++Y +
Sbjct: 124 LLLGVEVLRFVMIKEGAVTLGEGIVLFLIYVVYVAI 159
>UniRef50_A4FZ20 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
Methanococcus maripaludis|Rep: Na+/Ca+ antiporter, CaCA
family - Methanococcus maripaludis
Length = 320
Score = 56.0 bits (129), Expect = 2e-06
Identities = 39/144 (27%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 65 FLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI 124
F+LY++FG +L I +++FI I + LKI V AT ++ TS PE +
Sbjct: 5 FILYLIFG----GILLIYGSEWFIAGSISIAKHLKISNFVIGATIVAFGTSLPEIVTSSY 60
Query: 125 STFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVA 184
+ D+ +G VGS + N PI I R + ++ IY++ +LV
Sbjct: 61 AALSGSPDLAVGNAVGSCIANIGIILGINLLLY--PIIIKKREILKNGNIYLLATILLVI 118
Query: 185 FVWDGQIDWFEAMVLGILYILYFV 208
++G F+ ++L + I+Y +
Sbjct: 119 LGYNG-FSRFDGLILFLFMIIYVI 141
Score = 41.5 bits (93), Expect = 0.040
Identities = 22/59 (37%), Positives = 33/59 (55%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F I ES++G + +AFG LPE + +RR G I + N +G+N I AL + +I
Sbjct: 192 FNILESIIGFSLVAFGNSLPELATSISAARRNLGIIVLGNVIGSNIANICIALSVSAMI 250
>UniRef50_Q8PTQ3 Cluster: Sodium-calcium exchanger protein; n=1;
Methanosarcina mazei|Rep: Sodium-calcium exchanger
protein - Methanosarcina mazei (Methanosarcina frisia)
Length = 392
Score = 55.6 bits (128), Expect = 2e-06
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL + D F+ I + + + + T +S+ TS PEF ++ ++F S + IG
Sbjct: 14 LLLVKGADLFVTSSSWIAKRFGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGN 73
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
++GS + N + + + + RD I + ++ + + FV D +I FEA
Sbjct: 74 VLGSNIAN--IGLIVSTAALLSNVKTEELMLRRDGYIMLFSVFLFLLFVVDFRISRFEAF 131
Query: 198 VLGILYILYFVVMFNSMK 215
+ +LY +Y + + + +K
Sbjct: 132 IFLLLYFVYILFLLDKVK 149
Score = 39.9 bits (89), Expect = 0.12
Identities = 18/58 (31%), Positives = 31/58 (53%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
+PE+++G++ +A G LPE +R G I + N +G+N L LG L++
Sbjct: 279 VPETIIGISLVAVGTSLPELMVTVSAARNGYASIALGNVIGSNITNTLLILGCTGLVQ 336
Score = 39.1 bits (87), Expect = 0.22
Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 4/159 (2%)
Query: 54 IFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVA 113
++ E L + +FL + + I+ YFI L++P+ + + ++V
Sbjct: 234 VYETESLSESSFLKEFT-KLIASGIAIIIGAKYFIDKSIFFALLLEVPETIIGISLVAVG 292
Query: 114 TSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVL 173
TS PE V V + + + +G ++GS + N P+ + V
Sbjct: 293 TSLPELMVTVSAARNGYASIALGNVIGSNITN--TLLILGCTGLVQPLMVTGTAVYYITP 350
Query: 174 IYMVNISVLVAFVWDG-QIDWFEAMVLGILYILYFVVMF 211
+V +L+ F+ G +I E ++L +LY + V +F
Sbjct: 351 FMLVFSLLLLLFIRTGWRIKRHEGLILFLLYSGFMVFIF 389
Score = 35.9 bits (79), Expect = 2.0
Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 14/126 (11%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + E ++G+T ++ G +PE S S GI + N LG+N + +GL ++
Sbjct: 34 FGVSEFIIGLTLVSIGTSVPEFASSLTASFEQASGIVIGNVLGSN----IANIGL--IVS 87
Query: 340 TVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVV 399
T +L + + +++ G +LF+ F + R + +LY V
Sbjct: 88 TAAL-LSNVKTEELMLRRDG-------YIMLFSVFLFLLFVVDFRISRFEAFIFLLLYFV 139
Query: 400 FIVFAI 405
+I+F +
Sbjct: 140 YILFLL 145
>UniRef50_A7D2S9 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Na+/Ca+
antiporter, CaCA family - Halorubrum lacusprofundi ATCC
49239
Length = 326
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/249 (23%), Positives = 103/249 (41%), Gaps = 16/249 (6%)
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP 167
T +++ TS PE V V + ++G+G I+GS +N P+ +
Sbjct: 48 TIVAMGTSTPELVVTVDAALAGLGEIGVGNIIGSNAYNLAFILGAVSLLRVIPVERSL-- 105
Query: 168 VTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAAC 227
V RD +++ V A ++D + E +L L++ Y + + ID +A
Sbjct: 106 VHRDGAALVLSTLVGAAALFDRTVTGVEGALLAGLFVAYTAYLVRDERTARSIDTEYA-- 163
Query: 228 CKKNNGVTASLNDNNVSVEEGIDNKGF--NDPSPVTNGTTMTEKPAIDEKNGHTFFIPES 285
++ VT ++ D E G D + +G M E + ++ + +
Sbjct: 164 ---DSRVTGAIPDG--LSERGRDALLLVGGLALVLVSGHFMVEAASTLARSAG---VSDW 215
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
+G T +A G PE + RRG G+ V N +G+N +L +G+ +R L +
Sbjct: 216 AIGGTIVAAGTSTPELAVSLVAMRRGHVGMSVGNVVGSNVFNVLGIMGIAAFLR--PLAV 273
Query: 346 QGAENTAVL 354
GA VL
Sbjct: 274 GGAAIETVL 282
Score = 42.7 bits (96), Expect = 0.017
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + E +G+T +A G PE + G G IGV N +G+N+ + F LG L+R
Sbjct: 38 FGVGELTIGLTIVAMGTSTPELVVTVDAALAGLGEIGVGNIIGSNAYNLAFILGAVSLLR 97
Query: 340 TVSLE 344
+ +E
Sbjct: 98 VIPVE 102
Score = 39.1 bits (87), Expect = 0.22
Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 7/143 (4%)
Query: 48 DSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAA 107
DS G D +G L +V G+ L +V + + + +
Sbjct: 164 DSRVTGAIPDGLSERGRDALLLVGGL----ALVLVSGHFMVEAASTLARSAGVSDWAIGG 219
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP 167
T ++ TS PE V++++ M +G +VGS +FN P+A+
Sbjct: 220 TIVAAGTSTPELAVSLVAMRRGHVGMSVGNVVGSNVFN--VLGIMGIAAFLRPLAVGGAA 277
Query: 168 VTRDVLIYMVNISVLVAFVWDGQ 190
+ + + +V + V+V +W G+
Sbjct: 278 IETVLWLTVVTV-VMVVALWSGR 299
>UniRef50_Q6C1A1 Cluster: Similar to tr|P87122 Schizosaccharomyces
pombe CaCA sodium/calcium exchanger; n=1; Yarrowia
lipolytica|Rep: Similar to tr|P87122 Schizosaccharomyces
pombe CaCA sodium/calcium exchanger - Yarrowia
lipolytica (Candida lipolytica)
Length = 812
Score = 55.2 bits (127), Expect = 3e-06
Identities = 29/141 (20%), Positives = 65/141 (46%), Gaps = 2/141 (1%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
++ +++ + F L I +D+ P + I L + +++A TF++ P+ F S
Sbjct: 98 IMLLLWLLTLFMTLGIAASDFLCPNLGTISSLLGMSESLAGVTFLAFGNGSPDLFSTYSS 157
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ + IG ++G+A F P + + RD+ + + +AF
Sbjct: 158 MKIGSGSLAIGELIGAASF--ISAVVVGAMALARPFKVARKSFVRDIGFFTAAVLCTMAF 215
Query: 186 VWDGQIDWFEAMVLGILYILY 206
+ DG++ E +++ I+Y++Y
Sbjct: 216 ISDGKLRRSECILMLIIYMIY 236
Score = 37.5 bits (83), Expect = 0.66
Identities = 19/56 (33%), Positives = 28/56 (50%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES+ G+TFLAFG P+ S + + G G + + +GA S +G L R
Sbjct: 134 ESLAGVTFLAFGNGSPDLFSTYSSMKIGSGSLAIGELIGAASFISAVVVGAMALAR 189
>UniRef50_Q0C136 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Hyphomonas neptunium ATCC
15444|Rep: K+-dependent Na+/Ca+ exchanger
related-protein - Hyphomonas neptunium (strain ATCC
15444)
Length = 339
Score = 54.8 bits (126), Expect = 4e-06
Identities = 63/311 (20%), Positives = 118/311 (37%), Gaps = 17/311 (5%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ L I + V T + TS PE ++ + + IG +VGS + N
Sbjct: 27 VARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVLLVLAIA 86
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
+PI + + RD L + +L A +W Q ++ + I Y V+
Sbjct: 87 VIL--SPIIVHPNVIMRDGLFMLGATGLLCALIWFDQFSRISGFLMLAVLIGYLVLS--- 141
Query: 214 MKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAID 273
+++D+ + + + D + GI V + E
Sbjct: 142 ----IVLDQRRQDGTAQMHKEEGEVVDAQYGLVVGIVIAIAGLAGVVLGANLLVEGSVTL 197
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
+ I E+V+G+T +A G LPE + + + R + + + N +G+N IL LG
Sbjct: 198 ARQ---IGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGNVIGSNLFNILGILG 254
Query: 334 LPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFT---LRRTVG 390
+ L++ S ++G + + + +LF+ T L R G
Sbjct: 255 ITALVQPFS--VRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLFALTGRKLARWEG 312
Query: 391 IVLGILYVVFI 401
VL + YV+++
Sbjct: 313 AVLLLGYVLYM 323
>UniRef50_A5UM04 Cluster: Ca2+/Na+ antiporter; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Ca2+/Na+
antiporter - Methanobrevibacter smithii (strain PS /
ATCC 35061 / DSM 861)
Length = 313
Score = 54.8 bits (126), Expect = 4e-06
Identities = 64/272 (23%), Positives = 115/272 (42%), Gaps = 26/272 (9%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L+ +V I F +L I +D F+ I LKIP + T ++ TS PE V++ S
Sbjct: 5 LIQIVLLIVGFAIL-IKGSDIFVSGSSNIATILKIPTLIVGLTIVAFGTSAPEAAVSISS 63
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ + + + ++GS +FN + ++ + +D+ ++ ++V F
Sbjct: 64 SIQGSNALAVSNVIGSNIFNILGIIGICALLKELKLGENV--LNKDMPFLLIVSLLVVGF 121
Query: 186 V---WDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNN 242
+ WD + E +VL IL I Y + + K D + K G+ S+
Sbjct: 122 ILLSWD--LTRIEGIVLLILIIGYTAHLVYTSKKSKGADFVE----KPKFGIGRSI---- 171
Query: 243 VSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEAC 302
V V G+ V + + + + E +++G+T +A G LPE
Sbjct: 172 VYVVVGLAAIILGAQLVVNSSSYIAMACGMSE----------TLVGLTIVAIGTSLPELV 221
Query: 303 SIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
+ +R E + + N +G+N ILF LGL
Sbjct: 222 TSLTALKRDENQLVIGNVIGSNIFNILFVLGL 253
Score = 45.6 bits (103), Expect = 0.002
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Query: 63 GAFLLYVVFGIYTFTLLA-IVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFV 121
G ++YVV G+ L A +V N + + C + + + T +++ TS PE
Sbjct: 168 GRSIVYVVVGLAAIILGAQLVVNSSSY--IAMACG---MSETLVGLTIVAIGTSLPELVT 222
Query: 122 NVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISV 181
++ + E+ + IG ++GS +FN TPI ++ + L+ +V I
Sbjct: 223 SLTALKRDENQLVIGNVIGSNIFN--ILFVLGLSSTITPIPVNSNMIVDLGLMIIVTILC 280
Query: 182 LVAFVWDGQIDWFEAMVLGILYILY--FVVMFN 212
L+ + D E ++L L+ILY FV+ N
Sbjct: 281 LIFGKTQSKFDRKEGIILLGLFILYMAFVIFRN 313
Score = 45.2 bits (102), Expect = 0.003
Identities = 22/62 (35%), Positives = 35/62 (56%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP ++G+T +AFG PEA S +G + VSN +G+N IL +G+ L++ +
Sbjct: 38 IPTLIVGLTIVAFGTSAPEAAVSISSSIQGSNALAVSNVIGSNIFNILGIIGICALLKEL 97
Query: 342 SL 343
L
Sbjct: 98 KL 99
>UniRef50_Q9FKP2 Cluster: Na/Ca,K-exchanger-like protein; n=1;
Arabidopsis thaliana|Rep: Na/Ca,K-exchanger-like protein
- Arabidopsis thaliana (Mouse-ear cress)
Length = 559
Score = 54.4 bits (125), Expect = 5e-06
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 9/155 (5%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
G FLL++ + F LL ++YF +E + + L + VA T +S+ P+ F +
Sbjct: 91 GQFLLFLWL-LLLFYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFAS 149
Query: 123 VISTFLTES----DMGIGTIVGSALF-NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV 177
++S F+ ES D+G+ T+VG + F + I+ RD+ +
Sbjct: 150 LVS-FMGESKGTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCA 208
Query: 178 NISVLVAFVWDGQIDWFEAMVLGILYILY--FVVM 210
I L + G+I+++ A+ LY +Y FVV+
Sbjct: 209 AIGSLALILVYGKINFWGALGFCSLYAVYVAFVVL 243
>UniRef50_A0BIY1 Cluster: Chromosome undetermined scaffold_11, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_11,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 498
Score = 54.4 bits (125), Expect = 5e-06
Identities = 30/148 (20%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 65 FLLYVVFGIY-TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
F+L +F + F ++ + Y P +E I E L I Q+++A T ++ A + +
Sbjct: 49 FILMAIFVVLIVFRFMSTLVMFYLTPAIEFITEKLNISQSLSAVTLLAFANGAGDVVTAI 108
Query: 124 ISTFLTES-DMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
++T ++ IG++ G+ F + I + + RD+L Y+V ++
Sbjct: 109 VATETLDAISYNIGSLYGAGFFVATLVVGITIINSQSYIVMKSYFIWRDILFYIVATIIV 168
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ + G+ ++ L ++YI+ +++
Sbjct: 169 IIYGIVGEFSLIDSAFLLLIYIILVIIV 196
>UniRef50_A3I226 Cluster: Putative uncharacterized protein; n=2;
Bacteroidetes|Rep: Putative uncharacterized protein -
Algoriphagus sp. PR1
Length = 318
Score = 54.0 bits (124), Expect = 7e-06
Identities = 64/335 (19%), Positives = 136/335 (40%), Gaps = 32/335 (9%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL + D+ + ++ + K+ T ++ TS PE VN I++ D+ G
Sbjct: 13 LLLVKGADWLVDGASVLAKTHKVSDLAIGLTIVAFGTSAPELVVNSIASSDHLPDLVFGN 72
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
++GS FN P+++ V +++ + I +L +
Sbjct: 73 VIGSNNFNLFIILGIAGLIA--PLSVQSSTVWKEIPFSFLAIILL--------------L 116
Query: 198 VLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDP 257
+L Y + + + + F+LI + + N++ + +++ + K +
Sbjct: 117 ILANGYFHNYALSLSHLDGFILIVFFVGFLYYVFTQLKSEPNESEIIIKDYSNLKIWGLI 176
Query: 258 SPVTNGTTMTEKPAIDEK--NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGI 315
G + K +D +F + E ++G+T +A G LPE + + S + I
Sbjct: 177 LAGLAGLVIGGKLVVDNAVVMAQSFGVSEKIIGLTIVAAGTSLPELATSVVASLKKNNDI 236
Query: 316 GVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXW 375
+ N +G+N I LG+ +I + ++ ++ +L+ G F +
Sbjct: 237 AIGNIIGSNIFNIFLILGVSSIINPLDYQLSFNKDLYILL--GGTIF-----------LF 283
Query: 376 IVLFIGK-FTLRRTVGIVLGILYVVFIVFAILVEL 409
+ +F GK +L R +L + Y+V+I + + EL
Sbjct: 284 LAMFTGKRKSLDRWEAGILLLTYLVYIAYLVSKEL 318
>UniRef50_Q83F54 Cluster: Sodium/calcium antiporter family protein;
n=3; Coxiella burnetii|Rep: Sodium/calcium antiporter
family protein - Coxiella burnetii
Length = 322
Score = 53.6 bits (123), Expect = 9e-06
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
Query: 87 FIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNX 146
FI + LKIP V + TS PE V+ I+ F ++ + IG +VGS + N
Sbjct: 25 FITASAALARHLKIPSLVIGIILVGFGTSFPELIVSAIAAFHGKTQISIGNVVGSNIAN- 83
Query: 147 XXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
PI + R V ++ ++ V+ AF+W+G + E ++L +L IL+
Sbjct: 84 -IGLILGVVALIIPIEVHSRLVKWELPALIIISFVIGAFLWNGYLSRPEGIILILLLILH 142
Query: 207 FVVM 210
M
Sbjct: 143 LYWM 146
Score = 38.7 bits (86), Expect = 0.28
Identities = 19/48 (39%), Positives = 26/48 (54%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
L I V T ++V TS PEF ++ E D+ IG I+GS +FN
Sbjct: 202 LGISDLVIGLTIVTVCTSLPEFAATLMGVLKKEHDIAIGHIIGSNIFN 249
>UniRef50_Q7UGA8 Cluster: Probable sodium/calcium exchanger
antiporter; n=1; Pirellula sp.|Rep: Probable
sodium/calcium exchanger antiporter - Rhodopirellula
baltica
Length = 432
Score = 53.6 bits (123), Expect = 9e-06
Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTF-LTESD---MGIGTIVGSALFN---------X 146
+ + V T ++++S PE F +I+ F L++ D +GIGT GSALFN
Sbjct: 35 LSEGVRGGTINAISSSIPELFTTLIALFVLSDRDGFSIGIGTTAGSALFNGMIIPAVCIL 94
Query: 147 XXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
T + + R + RD + ++ +L+ + Q+ W++ ++L ++Y Y
Sbjct: 95 SVVGFVVMGVRVTSVNVSTRVLLRDGISLILCEFILILLINGEQLHWWQGLILMLMYATY 154
Query: 207 FVVMFNSMKA 216
V M +MK+
Sbjct: 155 LVYMLTTMKS 164
Score = 36.3 bits (80), Expect = 1.5
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 262 NGTTMTEKPAIDEKNGHTFF---IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVS 318
+G E P+ E G TF +P + + F + +P+ +R G+ V+
Sbjct: 251 SGPANVENPSY-ELFGQTFEGLGMPAMFVAVIFASMATSVPDTVMSIRDARDGDYDDAVA 309
Query: 319 NALGANSLAILFALGLPWLIRTV 341
NALG+N I FALG P + T+
Sbjct: 310 NALGSNIFDICFALGFPLFLYTL 332
>UniRef50_A4CMG2 Cluster: Sodium/calcium exchanger; n=3;
Flavobacteriales|Rep: Sodium/calcium exchanger -
Robiginitalea biformata HTCC2501
Length = 315
Score = 53.6 bits (123), Expect = 9e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ DL + V T +SV TS PE +VI+ E M +G ++GS +FN
Sbjct: 195 LAADLGVSDRVIGITVVSVGTSIPELAASVIAMAKREKAMSVGNLIGSNIFNLLAVLGLT 254
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLV---AFVWDG-QIDWFEAMVLGILY 203
P+ +D R +TRDV +M+ IS LV F G ++ W + +VL Y
Sbjct: 255 AILAPVPV-LDDRLLTRDV-FWMLGISFLVLPLVFFPKGLRLGWRDGIVLLACY 306
Score = 37.1 bits (82), Expect = 0.87
Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Query: 282 IPESVMGMTFLAFGGCLPE-ACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRT 340
+ + V+G+T ++ G +PE A S+ M++R E + V N +G+N +L LGL ++
Sbjct: 201 VSDRVIGITVVSVGTSIPELAASVIAMAKR-EKAMSVGNLIGSNIFNLLAVLGLTAILAP 259
Query: 341 V 341
V
Sbjct: 260 V 260
Score = 36.7 bits (81), Expect = 1.1
Identities = 18/48 (37%), Positives = 26/48 (54%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
L IP+ V T +S+ATS PE V+ + D+ +G +VGS N
Sbjct: 35 LSIPKIVIGMTVVSLATSAPELIVSAQAALAGYPDLALGNVVGSNTAN 82
>UniRef50_A1T0P3 Cluster: Na+/Ca+ antiporter, CaCA family protein
precursor; n=5; Proteobacteria|Rep: Na+/Ca+ antiporter,
CaCA family protein precursor - Psychromonas ingrahamii
(strain 37)
Length = 326
Score = 53.6 bits (123), Expect = 9e-06
Identities = 55/269 (20%), Positives = 107/269 (39%), Gaps = 21/269 (7%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
I F LL I D F+ I + + + TS PE V+ I+ +
Sbjct: 12 IIGFALL-IWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTG 70
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+ IG +GS + N P+ I + + R++ + + + + +WD ++
Sbjct: 71 LSIGNAIGSNITNIGLMLGVTAIFY--PLHIHSKLLKREMPLLLALLIFSLFLLWDQRLG 128
Query: 193 WFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDN---NVSVEEGI 249
+ + ++L +M A +L+ +W A + + + D VS + +
Sbjct: 129 FLDGLIL------------LTMMAAMLVFTVWEAKSHNTDSLPQEILDELPEEVSKRDAL 176
Query: 250 DNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSR 309
+ + + A+D F + + ++G+T +A G LPE + +R
Sbjct: 177 KWLIIGIVLLIASSRLLVWG-AVDVAT--YFGVSDLIIGLTIVAIGTSLPELAATIAAAR 233
Query: 310 RGEGGIGVSNALGANSLAILFALGLPWLI 338
+ E + V N +G+N IL + LP LI
Sbjct: 234 KKEFDLAVGNIIGSNIFNILGVMALPGLI 262
Score = 41.5 bits (93), Expect = 0.040
Identities = 41/183 (22%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Query: 42 ATGDSIDSFPDGIFTD--EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLK 99
A + DS P I + E++ + L +++ GI +L I + + +
Sbjct: 150 AKSHNTDSLPQEILDELPEEVSKRDALKWLIIGI----VLLIASSRLLVWGAVDVATYFG 205
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ + T +++ TS PE + + E D+ +G I+GS +FN
Sbjct: 206 VSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLAVGNIIGSNIFNILGVMALPGLIH-- 263
Query: 160 PIAIDMRPVTRD--VLIYMVNISVLVAFVW----DGQIDWFEAMVLGILYILYFVVMFNS 213
P D +TRD V+I + + +L + W + ++L YI Y V +F
Sbjct: 264 PDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAVLGRINGVILLTAYIAYMVWLFID 323
Query: 214 MKA 216
M A
Sbjct: 324 MSA 326
>UniRef50_A7QRH9 Cluster: Chromosome chr8 scaffold_150, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr8 scaffold_150, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 593
Score = 53.6 bits (123), Expect = 9e-06
Identities = 28/133 (21%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS-TFLTESDMG 134
F LL +YF +E + LK+ +A T +S+ + F +++S T ++ D+G
Sbjct: 122 FYLLGNTAANYFCSSLENLSRVLKLSPTIAGVTLLSLGNGAADVFASIVSFTRTSDGDVG 181
Query: 135 IGTIVGSALF-NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDW 193
+ ++G A F + I++D RDV+ +++ ++ L+ + G++ +
Sbjct: 182 LNIVLGGAFFVSSVVVGIISIFIGPRQISVDKPSFIRDVIFFLIALASLLVIIIIGKVSF 241
Query: 194 FEAMVLGILYILY 206
+ ++ +Y Y
Sbjct: 242 WGSVCFVSIYFFY 254
>UniRef50_A7PG90 Cluster: Chromosome chr6 scaffold_15, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr6 scaffold_15, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 562
Score = 53.6 bits (123), Expect = 9e-06
Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 5/159 (3%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSC 116
D L A +L++ + F LL +YF +E + LK+ N+A T +S+
Sbjct: 116 DPVLGYSALILWL---LVLFYLLGNTAANYFCCSLEGLSRILKLSPNIAGVTLLSLGNGA 172
Query: 117 PEFFVNVISTFLTESD-MGIGTIVGSALF-NXXXXXXXXXXXXXTPIAIDMRPVTRDVLI 174
P+ F +++S E++ +G+ +I+G A F + + +I+ DV
Sbjct: 173 PDLFASIVSFMGDETEKVGLNSILGGAFFVSSIVVGIISISVCHSRPSIERSSFIWDVTF 232
Query: 175 YMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
++++++ L+ + G+I+ + A+ LY +Y + + S
Sbjct: 233 FLLSLACLLVIIMLGKINLWGAISFFSLYFIYVLFISTS 271
>UniRef50_O83997 Cluster: Conserved hypothetical integral membrane
protein; n=1; Treponema pallidum|Rep: Conserved
hypothetical integral membrane protein - Treponema
pallidum
Length = 341
Score = 53.2 bits (122), Expect = 1e-05
Identities = 55/238 (23%), Positives = 94/238 (39%), Gaps = 16/238 (6%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
I + + AT +S+ T+ PE V+V + +D+ +G +GS + +
Sbjct: 48 ISEALLGATLVSLGTTTPEAAVSVYAALCGNADLALGNAIGSIVVDTGFILGLGALLARP 107
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVL 219
+A+D + R + + + L W G Y +F S+ A L
Sbjct: 108 GLALDTHLMRRHARVQLFVVCAL---------GWVTLPRFGARVHQYVGWLFLSLLALYL 158
Query: 220 -IDKIWAACCKKNNGVTASLNDNNV---SVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEK 275
+ W+A + TA+L + SV + G V + P + E
Sbjct: 159 WVSLRWSALPHAPDTRTAALPADKTDTRSVCRLLLQLGGGIGFLVLGSRVLI--PTV-EI 215
Query: 276 NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
+P ++ T +AFG +PE S RRG G + V N +GA+ L +LF +G
Sbjct: 216 MALRAGVPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAVGNIVGADILNVLFVVG 273
Score = 36.3 bits (80), Expect = 1.5
Identities = 17/58 (29%), Positives = 29/58 (50%)
Query: 88 IPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
IP VE++ +P + AAT ++ TS PE + + + +G IVG+ + N
Sbjct: 210 IPTVEIMALRAGVPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAVGNIVGADILN 267
>UniRef50_A4RWJ1 Cluster: CaCA family transporter: sodium
ion/calcium ion; n=2; Ostreococcus|Rep: CaCA family
transporter: sodium ion/calcium ion - Ostreococcus
lucimarinus CCE9901
Length = 603
Score = 53.2 bits (122), Expect = 1e-05
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 9/149 (6%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF---LTESD 132
F LA V +F+P + I L + +VA AT +S P+ F + + + ES
Sbjct: 100 FAALASVAERFFVPALRNIARGLALRDDVAGATLLSFGNGAPDIFAQIAALSHEDVAESA 159
Query: 133 -MGIGTIVGSALFNXXXXX-----XXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
+ +G + G+ F + +D RDV Y V ++ + F
Sbjct: 160 ALAVGAVTGAGAFIASFVFPCVVLIATRAASGRGLVLDKWNFGRDVGFYAVASAMALGFF 219
Query: 187 WDGQIDWFEAMVLGILYILYFVVMFNSMK 215
DG+++ +EA L LY Y V+ + +
Sbjct: 220 LDGRVEAYEAAALFSLYAAYLFVLLSGRR 248
>UniRef50_A7DSA3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Na+/Ca+
antiporter, CaCA family - Candidatus Nitrosopumilus
maritimus SCM1
Length = 296
Score = 53.2 bits (122), Expect = 1e-05
Identities = 57/244 (23%), Positives = 108/244 (44%), Gaps = 24/244 (9%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I +I V T ++ TS PE ++ + S + +G I+GS + N
Sbjct: 16 IARKFRISNLVIGMTIVAYGTSTPELAASIAAAG-EHSAIILGNIIGSNIANVGMVIGIA 74
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVW-DGQIDWFEAMVLGI-LYILYFVVMF 211
P++I + +++ I M+ +SVL+ + DG++ ++ ++L + L + +
Sbjct: 75 AIL--VPLSIHKSILRKEIPI-MLGVSVLLILISIDGELSTYDGILLLVGLGVFGYYTFK 131
Query: 212 NSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE-GIDNKGFNDPSPVTNGTTMTEKP 270
++MK +++N NNV ++ G+ G + G +T
Sbjct: 132 DAMKR------------REDNKDDIQQGGNNVYLKSIGLIGLGIG---LLYVGALLTVDN 176
Query: 271 AIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILF 330
A+ F + E ++G+T +A G LPE + I R+G IGV N +G+N IL
Sbjct: 177 AVILAK--EFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILM 234
Query: 331 ALGL 334
+G+
Sbjct: 235 IMGV 238
Score = 47.2 bits (107), Expect = 8e-04
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 3/119 (2%)
Query: 93 LICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXX 152
++ ++ + + + T +++ TS PE ++I+ SD+G+G I+GS ++N
Sbjct: 179 ILAKEFGLSEKIIGLTVIAIGTSLPELITSIIAIRKGHSDIGVGNIIGSNIYNILMIMGV 238
Query: 153 XXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
I+ D+ V ++I + +IS+L+ + G I+ + L I Y+ Y V+ F
Sbjct: 239 GAALGGVMISDDVY-VDYAIMI-LFSISLLIG-LKTGVINRAMGVCLAIGYVTYLVLTF 294
>UniRef50_Q2S2Q5 Cluster: K+-dependent Na+/Ca+ exchanger-like
protein; n=1; Salinibacter ruber DSM 13855|Rep:
K+-dependent Na+/Ca+ exchanger-like protein -
Salinibacter ruber (strain DSM 13855)
Length = 317
Score = 52.8 bits (121), Expect = 2e-05
Identities = 64/271 (23%), Positives = 115/271 (42%), Gaps = 18/271 (6%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+LYV F + LL + + I I I + T +++ TS PE+ VNV +
Sbjct: 2 ILYV-FLFFVGLLLLYLGAEGLIQGASSIALQYGIRPVILGLTVVALGTSMPEYLVNVFA 60
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
ES + IG I+GS + N P+A+ + R+ Y V + V+V F
Sbjct: 61 LISGESPLAIGNIIGSNISN--VALILGACAVVLPLAVTPEVLRRE---YPVMLGVMVLF 115
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLID---KIWAACCKKNNGVTASLNDNN 242
+ +D V+G + VV+ + + A+V D + G + + +
Sbjct: 116 -YLCALDG----VIGARDGVLMVVLLSGLAAYVFYDAHRTTRGTVLESMEGELDAADPDL 170
Query: 243 VSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEAC 302
++ + + G +T G + A+ + I V+G+T +A G LPE
Sbjct: 171 STLAKAVYVIG--GMGGLTLGAHLMVDNALAISD--VLNIDHVVIGLTVVAIGTSLPELA 226
Query: 303 SIFIMSRRGEGGIGVSNALGANSLAILFALG 333
+ + + + E + V N +G+N L +LF +G
Sbjct: 227 ASMVGTLKQEVDMTVGNVIGSNLLNVLFVVG 257
Score = 48.4 bits (110), Expect = 4e-04
Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSC 116
D L A +YV+ G+ TL A + D + I + L I V T +++ TS
Sbjct: 167 DPDLSTLAKAVYVIGGMGGLTLGAHLMVDNALA----ISDVLNIDHVVIGLTVVAIGTSL 222
Query: 117 PEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYM 176
PE +++ T E DM +G ++GS L N PI +D + + +
Sbjct: 223 PELAASMVGTLKQEVDMTVGNVIGSNLLN--VLFVVGTLAIAEPITVDPETIRLHFPVML 280
Query: 177 VNISVLVAFV-WDGQIDWFEAMVLGILYILYFVVMF 211
++LV WD +I E + I ++ + V ++
Sbjct: 281 GFCALLVPLTWWDQKITRVEGAFMVIAFLGFMVFLY 316
>UniRef50_Q48E89 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=4; Pseudomonas syringae group|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Pseudomonas syringae pv. phaseolicola (strain 1448A /
Race 6)
Length = 343
Score = 52.4 bits (120), Expect = 2e-05
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Query: 93 LICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXX 152
+I L + + + T +++ TS P ++I+ F E D+ +G ++GS LFN
Sbjct: 184 VIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGV 243
Query: 153 XXXXXXTPIAIDMRPVTRDVLIYMVNISVL-VAFVWDG-QIDWFEAMVLGILYILY 206
P+ + + D+ I M+ +S+L V + G +ID E + L LY+ Y
Sbjct: 244 TALFAPVPLTVSPNAMVFDLPI-MLGVSLLCVPLFYSGYRIDRMEGVFLLSLYLTY 298
Score = 43.6 bits (98), Expect = 0.010
Identities = 22/64 (34%), Positives = 34/64 (53%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ E ++G+T +A G LP + I + RGE I V N +G+N +L LG+ L V
Sbjct: 191 LSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGVLGVTALFAPV 250
Query: 342 SLEI 345
L +
Sbjct: 251 PLTV 254
Score = 39.1 bits (87), Expect = 0.22
Identities = 21/113 (18%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 99 KIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXX 158
K+ + T +++ TS P+ V++ + F +D+ +G+++G +FN
Sbjct: 27 KVRPLLIGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFN--VLVILGLCALI 84
Query: 159 TPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL--GILYILYFVV 209
P+ + + + D+ + + + + W+G+ F+ +L G+L L ++
Sbjct: 85 IPLRVARQVLHIDIPLMIGACLLAIGLSWNGEFSKFDGALLLAGLLVCLIVII 137
>UniRef50_Q5E7V8 Cluster: Sodium-calcium exchanger; n=45;
Proteobacteria|Rep: Sodium-calcium exchanger - Vibrio
fischeri (strain ATCC 700601 / ES114)
Length = 323
Score = 52.0 bits (119), Expect = 3e-05
Identities = 54/253 (21%), Positives = 106/253 (41%), Gaps = 24/253 (9%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
V T +++ +S PE V+ + ++D +G ++GS + N P+AI
Sbjct: 42 VIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNIANIALILGITALIK--PLAI 99
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
+ R++ + ++ + +++ + ++E ++L L+ + + M K
Sbjct: 100 SSAIIRRELPLMLMVTLLAGGIMFNNYLGFYEGLLLIGLFACFIIAMLYISKN------- 152
Query: 224 WAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPA---IDEKN--GH 278
++ NG L + + EG+ N V G + A ID
Sbjct: 153 -----EQQNG-DILLEEQESEIPEGVANG--KALFWVVVGLILLPVGANMLIDNAVVIAK 204
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F + E V+G+T +A G LPE + +GE + N +G+N IL +G+P LI
Sbjct: 205 YFGMSELVIGLTIIALGTSLPELAASVAGVLKGEDDMAAGNIIGSNVFNILAVMGIPALI 264
Query: 339 R--TVSLEIQGAE 349
+S ++ G +
Sbjct: 265 NPSEISPDLMGRD 277
Score = 43.2 bits (97), Expect = 0.013
Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 10/160 (6%)
Query: 58 EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCP 117
E + G L +VV G+ LL + N I +I + + + V T +++ TS P
Sbjct: 170 EGVANGKALFWVVVGLI---LLPVGAN-MLIDNAVVIAKYFGMSELVIGLTIIALGTSLP 225
Query: 118 EFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV 177
E +V E DM G I+GS +FN + I+ D+ + RD + M+
Sbjct: 226 ELAASVAGVLKGEDDMAAGNIIGSNVFNILAVMGIPALINPSEISPDL--MGRDFYV-ML 282
Query: 178 NISVLVAFVWDGQ---IDWFEAMVLGILYILYFVVMFNSM 214
+S+L+ + G+ I+ E +L + +Y +F +M
Sbjct: 283 GVSILLLIMALGKSRSINRIEGGILVTCFCVYQGYLFLNM 322
>UniRef50_Q1VKR7 Cluster: Probable sodium/calcium exchanger
antiporter; n=1; Psychroflexus torquis ATCC 700755|Rep:
Probable sodium/calcium exchanger antiporter -
Psychroflexus torquis ATCC 700755
Length = 158
Score = 52.0 bits (119), Expect = 3e-05
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 9/119 (7%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMG----IGTIVGSALFNXXXXXXXXXXXXXT 159
V AT +VA+S PE F+ + F + +G +GT GS LFN +
Sbjct: 40 VKGATINAVASSMPELFIALFFLFFLKDVVGFSGGLGTSFGSVLFNSLIIPSAAVLGVLS 99
Query: 160 P-----IAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
+++ + + RD + +L+ F+ G+I W E+ VL +Y+LY + +F +
Sbjct: 100 KTNKKSVSVSRKIILRDGFWLLFVEFMLIYFIQQGEISWIESSVLITIYVLYVMYLFKT 158
>UniRef50_Q0A6H1 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Na+/Ca+
antiporter, CaCA family precursor - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 327
Score = 52.0 bits (119), Expect = 3e-05
Identities = 24/63 (38%), Positives = 38/63 (60%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ E+V+G+T +A G LPE + +RR +G I + N +G+N +L LGL +R V
Sbjct: 208 VAETVVGLTLVAVGTSLPELATCLAAARRSQGDIAIGNIIGSNIFNLLGVLGLAATLRPV 267
Query: 342 SLE 344
+LE
Sbjct: 268 ALE 270
Score = 37.5 bits (83), Expect = 0.66
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 6/120 (5%)
Query: 52 DGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMS 111
+G+ D R LL+++ G+ + A + + E + + V T ++
Sbjct: 164 NGLPEDAPTRLPRALLWLLLGLVVLLISAQTA----VWAATGLAERAGVAETVVGLTLVA 219
Query: 112 VATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRD 171
V TS PE + + ++ D+ IG I+GS +FN P+A++ ++RD
Sbjct: 220 VGTSLPELATCLAAARRSQGDIAIGNIIGSNIFN--LLGVLGLAATLRPVALEPGILSRD 277
Score = 35.1 bits (77), Expect = 3.5
Identities = 17/49 (34%), Positives = 27/49 (55%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
++G+T +AFG PE + + G G+ V NA+G+N + LGL
Sbjct: 39 LVGLTIVAFGTSAPELLVSALAALAGSPGLAVGNAIGSNIANMGLILGL 87
>UniRef50_A0NYH3 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=3; Rhodobacterales|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Stappia aggregata
IAM 12614
Length = 337
Score = 52.0 bits (119), Expect = 3e-05
Identities = 27/81 (33%), Positives = 40/81 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP V+G+T +AFG PE + G GGI + N +G+N +L LG+P LI
Sbjct: 35 IPNLVIGLTIVAFGTSAPELVISLKAALEGAGGIAIGNVVGSNIANVLLVLGMPALIAAT 94
Query: 342 SLEIQGAENTAVLINSAGIDF 362
GA A+ + + + F
Sbjct: 95 PCGETGATRNALFMVAVTVVF 115
Score = 49.2 bits (112), Expect = 2e-04
Identities = 54/267 (20%), Positives = 103/267 (38%), Gaps = 8/267 (2%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
++ I+ D + I + L IP V T ++ TS PE +++ + + IG
Sbjct: 13 VVLIIAGDVLVRGSVGIAQRLGIPNLVIGLTIVAFGTSAPELVISLKAALEGAGGIAIGN 72
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
+VGS + N TP TR+ L + V +A + I +
Sbjct: 73 VVGSNIANVLLVLGMPALIAATPCG--ETGATRNALFMVAVTVVFMALCFFIPIGLTAGV 130
Query: 198 VLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNN-VSVEEGIDNKGFND 256
+L L ++ + K AA + D++ + E + + +
Sbjct: 131 ILLALLGVFLAASTMMARKHRKEQKAIAAASAGAAAAEIEVEDDDGLDDVEDVPDSIWIA 190
Query: 257 PSPVTNGTTMTEKPAIDEKNGHTFF-----IPESVMGMTFLAFGGCLPEACSIFIMSRRG 311
+ + G A +G T + E+V+G+T +A G LPE + + + R
Sbjct: 191 LAYIVLGLVGLPLGAHFTISGATSIATSWGVSEAVIGLTVIALGTSLPELATTVMAAIRQ 250
Query: 312 EGGIGVSNALGANSLAILFALGLPWLI 338
G + + N +G+N +L +G+ +I
Sbjct: 251 HGAVAIGNVIGSNVFNLLAIIGITAVI 277
>UniRef50_Q8W0Q9 Cluster: K-exchanger-like protein; n=3;
Poaceae|Rep: K-exchanger-like protein - Sorghum bicolor
(Sorghum) (Sorghum vulgare)
Length = 573
Score = 52.0 bits (119), Expect = 3e-05
Identities = 34/145 (23%), Positives = 67/145 (46%), Gaps = 4/145 (2%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTE-S 131
+ F LL ++YF +E + L++P VA T +S+ P+ F +V+S +
Sbjct: 117 VVLFYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVSFASGDGG 176
Query: 132 DMGIGTIVGSALFNXXXXX---XXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
+G+ + +G ALF + ++ R RD+ ++ + L+A + +
Sbjct: 177 GVGLSSALGGALFVSTVVAGVVALAVGGARGGVVVEWRGFVRDLCFLLLALCYLLAVLVN 236
Query: 189 GQIDWFEAMVLGILYILYFVVMFNS 213
G I + A+ LY+ Y V+++ S
Sbjct: 237 GVITVWVAVSFVSLYVGYVVLVWTS 261
>UniRef50_Q1DQC0 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Coccidioides immitis
Length = 1013
Score = 52.0 bits (119), Expect = 3e-05
Identities = 30/152 (19%), Positives = 65/152 (42%), Gaps = 2/152 (1%)
Query: 59 QLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPE 118
Q + AF++ ++ F+ + I +D+ + I L + +++ TF++ P+
Sbjct: 112 QTKPLAFVIIALWLSLLFSTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPD 171
Query: 119 FFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVN 178
F + + IG ++G+A F P + R RD+ +
Sbjct: 172 VFSTFAAMSSNSGSLAIGELIGAAGF--ISAVVAGSMALVRPFRVARRSFVRDIAFFTCA 229
Query: 179 ISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+V + F+ DG++ +E +++ YI Y V +
Sbjct: 230 ATVSLVFIADGKLYIWECVLMIGFYIFYVVTV 261
Score = 35.5 bits (78), Expect = 2.7
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES+ G+TFLAFG P+ S F G + + +GA G L+R
Sbjct: 155 ESLTGVTFLAFGNGSPDVFSTFAAMSSNSGSLAIGELIGAAGFISAVVAGSMALVR 210
>UniRef50_A6R7X4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 858
Score = 52.0 bits (119), Expect = 3e-05
Identities = 32/148 (21%), Positives = 64/148 (43%), Gaps = 3/148 (2%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
AF + V+ F + I +D+ + I L + +++ TF++ P+ F
Sbjct: 174 AFAILAVWLAVLFNTIGIAASDFLCVNLSTIASILGMSESLTGVTFLAFGNGSPDVFSTF 233
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ + IG +VG+A F P + R RDV+ ++ + S +
Sbjct: 234 AAMNSNSGGLAIGELVGAAGF--ITAVVAGSMALVRPFRVARRSFVRDVVFFVFSASFTM 291
Query: 184 AFVWDGQIDWFEAMVLGILYILY-FVVM 210
+ DG++ +E + + + Y+ Y FVV+
Sbjct: 292 VLLADGKLYAWECVAMILSYVFYVFVVV 319
Score = 38.3 bits (85), Expect = 0.38
Identities = 19/56 (33%), Positives = 26/56 (46%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES+ G+TFLAFG P+ S F GG+ + +GA G L+R
Sbjct: 212 ESLTGVTFLAFGNGSPDVFSTFAAMNSNSGGLAIGELVGAAGFITAVVAGSMALVR 267
>UniRef50_A3VUJ1 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Parvularcula bermudensis
HTCC2503|Rep: K+-dependent Na+/Ca+ exchanger
related-protein - Parvularcula bermudensis HTCC2503
Length = 327
Score = 51.6 bits (118), Expect = 4e-05
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 12/121 (9%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ E ++G+T +AFG LPE ++ +R+ E + V N +G+N ILF G
Sbjct: 206 VREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFNILFVGG-------- 257
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
G T V + + I L++ + T+ RTVGI+ + Y+ +I
Sbjct: 258 ---AMGVFGTTVFSDPGTKIYDVPAMVVAALALAIPLYL-RMTITRTVGILFILAYIAYI 313
Query: 402 V 402
V
Sbjct: 314 V 314
Score = 49.6 bits (113), Expect = 2e-04
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP ++G+T +AFG PE G+ GI V N +G+N + LGLP LI +
Sbjct: 35 IPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNIVGSNIANVFLVLGLPALISAI 94
Query: 342 SLEIQ--GAENTAVLINSAGIDF 362
SL G + +L +AG F
Sbjct: 95 SLSGPGLGRHGSVMLAATAGFAF 117
Score = 36.3 bits (80), Expect = 1.5
Identities = 18/67 (26%), Positives = 33/67 (49%)
Query: 79 LAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTI 138
+ +V D+ + I L IP + T ++ TS PE V++ + ++ + +G I
Sbjct: 14 ILLVAGDFLVRGAVGIATRLGIPSLLIGLTIVAFGTSAPELVVSINAVVTGDNGIAVGNI 73
Query: 139 VGSALFN 145
VGS + N
Sbjct: 74 VGSNIAN 80
Score = 33.9 bits (74), Expect = 8.1
Identities = 13/49 (26%), Positives = 26/49 (53%)
Query: 97 DLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
DL + + + T ++ TS PE + + E+ + +G ++GS +FN
Sbjct: 203 DLGVREELVGLTLIAFGTSLPELATVIAAARKAEASVAVGNVIGSNIFN 251
>UniRef50_A7AHL6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 313
Score = 51.2 bits (117), Expect = 5e-05
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I ++L + + V T ++ TS PE ++++ + ++D+ IG IVGS LFN
Sbjct: 194 IAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSC 253
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISV-LVAFVWDGQ-IDWFEAMVLGILYILY 206
I+ + V L+ M+ ISV L+ V GQ I E VL + Y++Y
Sbjct: 254 SLIH----PIEAKNVNYIDLLVMLGISVLLLPLVKSGQKISRTEGFVLILFYVIY 304
Score = 50.0 bits (114), Expect = 1e-04
Identities = 48/243 (19%), Positives = 97/243 (39%), Gaps = 17/243 (6%)
Query: 99 KIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXX 158
KI V T ++ TS PE V++ +T + D+ IG IVGS +FN
Sbjct: 34 KISPLVVGLTIVAFGTSAPELVVSLNATLSGQGDIAIGNIVGSNIFN--IGVILGVSATI 91
Query: 159 TPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFV 218
P+ + + + D+ + + + W+G + E L+ L ++++ F
Sbjct: 92 CPLQVKKQLLRIDIPVMLAATVLFTILFWNGTLGRTEG-----LFFLTGIIIYTIFSLFY 146
Query: 219 LIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGH 278
++ + +++ G+ F V N ++ ++ +
Sbjct: 147 SRKHGTEGSSQELEEQPKHWAVDTLAIVGGLVVLVFASRLLVDNAVSIAKELGVS----- 201
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
E+V+G+T +A G +PE + + + + + I + N +G+N IL G LI
Sbjct: 202 -----EAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVGSNLFNILTIAGSCSLI 256
Query: 339 RTV 341
+
Sbjct: 257 HPI 259
>UniRef50_A5EXP0 Cluster: K+-dependent Na+-Ca+ exchanger related
family protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
K+-dependent Na+-Ca+ exchanger related family protein -
Dichelobacter nodosus (strain VCS1703A)
Length = 325
Score = 51.2 bits (117), Expect = 5e-05
Identities = 37/147 (25%), Positives = 69/147 (46%), Gaps = 12/147 (8%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L+Y V G+ +L I+ + + I + L I + T ++V TS PE ++++
Sbjct: 173 LVYSVGGL----VLLIIASRIMVWGAVSIAQALNISDLIIGLTIIAVGTSLPELASSIVA 228
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
++DM +G IVGS +FN TP A + +TRD+++ + +VL
Sbjct: 229 VRKNQTDMALGNIVGSNIFN--ALAVVGLSGLITPFAAEPEILTRDLVVMTIVTAVLFVM 286
Query: 186 ------VWDGQIDWFEAMVLGILYILY 206
+ ++ ++L I+Y+LY
Sbjct: 287 GLIRRRDHNAELKLAHGLILLIIYLLY 313
Score = 39.1 bits (87), Expect = 0.22
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
I + ++G+T +A G LPE S + R+ + + + N +G+N L +GL LI
Sbjct: 203 ISDLIIGLTIIAVGTSLPELASSIVAVRKNQTDMALGNIVGSNIFNALAVVGLSGLITPF 262
Query: 342 SLE 344
+ E
Sbjct: 263 AAE 265
Score = 38.7 bits (86), Expect = 0.28
Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 6/142 (4%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+++ + I +L + D+F+ + + + V + TS PE V+V +
Sbjct: 3 IIWAIGAIIIGLILLVKSADWFVDGAAALAKIAGLSPLVIGIVIIGFGTSAPEMIVSVTA 62
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
S + +G GS + N PI + + V+ ++ I + + L+ F
Sbjct: 63 ALNHNSGIALGNAYGSNIVN--IGLILGISALIAPIPMPKKLVSGELFILL--LITLLCF 118
Query: 186 VW--DGQIDWFEAMVLGILYIL 205
+W D I EA+V+ +L+ +
Sbjct: 119 LWLQDDYISRSEALVMLVLFFI 140
>UniRef50_A6RWV6 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1060
Score = 51.2 bits (117), Expect = 5e-05
Identities = 29/147 (19%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
AF + +++ F+ + I +D+F + I L + +++A TF++ P+ F
Sbjct: 118 AFAILILWLGLLFSTIGIAASDFFCINLSTIASILGMSESMAGVTFLAFGNGSPDVFSTF 177
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ + +G ++G+A F + + RD+ ++V S +
Sbjct: 178 AAMSSHSGSLAVGELIGAAGF--ITAVVAGSMALVREFKVGKKTFVRDIGFFIVAASFSM 235
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
F+ DG + +E V+ Y+ Y V++
Sbjct: 236 VFLADGALHLWECFVMIGFYLFYVVIV 262
Score = 35.5 bits (78), Expect = 2.7
Identities = 19/56 (33%), Positives = 25/56 (44%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES+ G+TFLAFG P+ S F G + V +GA G L+R
Sbjct: 156 ESMAGVTFLAFGNGSPDVFSTFAAMSSHSGSLAVGELIGAAGFITAVVAGSMALVR 211
>UniRef50_UPI0001509E2E Cluster: Sodium/calcium exchanger protein;
n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
exchanger protein - Tetrahymena thermophila SB210
Length = 602
Score = 50.8 bits (116), Expect = 7e-05
Identities = 29/147 (19%), Positives = 67/147 (45%), Gaps = 3/147 (2%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
LL V+ + F +L+ Y P + + L++ ++VA T +++ P+ +I+
Sbjct: 54 LLTVLVPLMAFHMLSSTAESYLSPALAKCSKILRLSESVAGVTLLALGNGAPDVITAIIA 113
Query: 126 TFLTES--DMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ IG+I G+ LF I ID + RD++ Y++ V++
Sbjct: 114 GGDDNGGISIAIGSIFGAGLFVTTATLSAVIFHGKN-IKIDKKTFMRDMVFYLLGCLVIL 172
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
+ G+++ + + +Y+++ V++
Sbjct: 173 VYAIIGKVNIIMSSIFMSIYLIFLVIV 199
>UniRef50_Q9KFL4 Cluster: BH0465 protein; n=3; Bacillus|Rep: BH0465
protein - Bacillus halodurans
Length = 318
Score = 50.8 bits (116), Expect = 7e-05
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+ + T +++ TS PE ++ + ES++ +G IVGS++FN TP+
Sbjct: 208 ETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFN--IFFVLGTAATITPM 265
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFV 208
+D R V +L+ + + +LV + +E ++L YI Y V
Sbjct: 266 HVDSRVVVDLLLLIFLTLLLLVFSRTRYTVGKYEGLILASFYIGYMV 312
Score = 39.1 bits (87), Expect = 0.22
Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 6/118 (5%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
++G+T +AFG PEA + I + G + + N +G+N I +GL L+ + +
Sbjct: 37 LIGLTIVAFGTSSPEATASIIAALNGNPDVALGNVIGSNMFNITLVVGLTALLSPLIV-- 94
Query: 346 QGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFIVF 403
A L ++ + TL R+ G++L +++ VF+ +
Sbjct: 95 ----TNATLRKEIPFTLLASIALYIFINDQMIEGAVESTLSRSEGLILLLIFCVFLYY 148
Score = 37.5 bits (83), Expect = 0.66
Identities = 26/129 (20%), Positives = 54/129 (41%), Gaps = 6/129 (4%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D+F+ I L + + T ++ TS PE ++I+ D+ +G ++GS +F
Sbjct: 18 DFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNGNPDVALGNVIGSNMF 77
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL----G 200
N +P+ + + +++ ++ L F+ D I+ L G
Sbjct: 78 N--ITLVVGLTALLSPLIVTNATLRKEIPFTLLASIALYIFINDQMIEGAVESTLSRSEG 135
Query: 201 ILYILYFVV 209
++ +L F V
Sbjct: 136 LILLLIFCV 144
Score = 35.5 bits (78), Expect = 2.7
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
E+++G+T +A G LPE + + + E I + N +G++ I F LG I + +
Sbjct: 208 ETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNIVGSSIFNIFFVLGTAATITPMHV 267
Query: 344 EIQGAENTAVLI 355
+ + + +LI
Sbjct: 268 DSRVVVDLLLLI 279
>UniRef50_Q3VWE2 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Prosthecochloris aestuarii DSM
271|Rep: K+-dependent Na+/Ca+ exchanger related-protein
- Prosthecochloris aestuarii DSM 271
Length = 334
Score = 50.8 bits (116), Expect = 7e-05
Identities = 57/242 (23%), Positives = 109/242 (45%), Gaps = 20/242 (8%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESD-MGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
V T ++ TS PEF V+ + + +SD + +G ++GS + N PI
Sbjct: 49 VIGLTVVAYGTSMPEFVVSFFAHVVEDSDSISLGNVIGSNITNIGLILGLSALIF--PIH 106
Query: 163 IDMRPVTRDVLIYMVNISVLVAFV-WDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLID 221
I + + R+ +++ IS++V + DG I E G+L+ L +F + + +
Sbjct: 107 IAFQSI-RNQSLFLFGISMIVYLLALDGTISRAEG---GVLFTLLCGYLFVMYRTPEIAE 162
Query: 222 KIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFF 281
+ + + + + + + + V + + G S V + + E+
Sbjct: 163 ESFEEAPESQDILPLATSISLVGAGSVLLSTGAW--SFVKSSVWIAEQ----------LN 210
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP+ +G++ +A G LPE + + + R E I V N +G+N ILF LG +I+ V
Sbjct: 211 IPKLYIGLSIVALGTSLPELATSLVGAIRRESEISVGNLIGSNIFNILFVLGGVSMIKPV 270
Query: 342 SL 343
S+
Sbjct: 271 SV 272
Score = 41.1 bits (92), Expect = 0.053
Identities = 17/59 (28%), Positives = 32/59 (54%)
Query: 87 FIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
F+ I E L IP+ + +++ TS PE +++ ES++ +G ++GS +FN
Sbjct: 198 FVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRRESEISVGNLIGSNIFN 256
Score = 37.5 bits (83), Expect = 0.66
Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 280 FFIPESVMGMTFLAFGGCLPE-ACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F I V+G+T +A+G +PE S F I + N +G+N I LGL LI
Sbjct: 43 FGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSISLGNVIGSNITNIGLILGLSALI 102
Query: 339 RTVSLEIQGAENTAVLI 355
+ + Q N ++ +
Sbjct: 103 FPIHIAFQSIRNQSLFL 119
>UniRef50_A5GJM9 Cluster: Ca2+/Na+ antiporter; n=23;
Cyanobacteria|Rep: Ca2+/Na+ antiporter - Synechococcus
sp. (strain WH7803)
Length = 372
Score = 50.8 bits (116), Expect = 7e-05
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L + Q V T +S TS PE ++++ +D+ IG +VGS L N
Sbjct: 205 LGVSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDLAIGNVVGSNLLNQLLVLGASAVAA 264
Query: 158 XTPIAIDMRP--VTRDVLIYMVNISVLVAFVWD-GQIDWFEAMVLGILYILYFV 208
+ + P + RD+ + ++ + W GQI E +L LY+ Y V
Sbjct: 265 AGGAGLQVSPMLIARDLPVMVLAALACLPIFWTRGQITRLEGGILVTLYVFYVV 318
Score = 44.4 bits (100), Expect = 0.006
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
IPQ V T +S TS PE FV++ S + + +VGS +FN
Sbjct: 38 IPQLVIGLTVVSFGTSAPELFVSLSSVTQGFDALAVSNVVGSNIFN--VMVVLGSSALVM 95
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL 199
P+ ++ R V RDV + + + + G++ W + L
Sbjct: 96 PLRVESRLVRRDVPLLIAVSAAVWGMASAGRVTWQAGIAL 135
Score = 39.5 bits (88), Expect = 0.16
Identities = 20/65 (30%), Positives = 34/65 (52%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F IP+ V+G+T ++FG PE +G + VSN +G+N ++ LG L+
Sbjct: 36 FGIPQLVIGLTVVSFGTSAPELFVSLSSVTQGFDALAVSNVVGSNIFNVMVVLGSSALVM 95
Query: 340 TVSLE 344
+ +E
Sbjct: 96 PLRVE 100
Score = 35.5 bits (78), Expect = 2.7
Identities = 14/52 (26%), Positives = 30/52 (57%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
+ ++V+G+T ++ G +PE + + + +G + + N +G+N L L LG
Sbjct: 207 VSQAVIGLTIVSAGTSMPELITSLVAAVKGRTDLAIGNVVGSNLLNQLLVLG 258
>UniRef50_A3I290 Cluster: Sodium/calcium exchanger; n=1;
Algoriphagus sp. PR1|Rep: Sodium/calcium exchanger -
Algoriphagus sp. PR1
Length = 312
Score = 50.8 bits (116), Expect = 7e-05
Identities = 60/276 (21%), Positives = 114/276 (41%), Gaps = 16/276 (5%)
Query: 68 YVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF 127
YV+ G+ LL + I L + + T ++ TS PE V+V +
Sbjct: 4 YVLLGLGLIILL--YGGKILVDGASAIAVKLGMSAGLIGLTIVAFGTSAPELLVSVNAAL 61
Query: 128 LTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVW 187
SD+ +G ++GS + N PI I + D I ++ + A +
Sbjct: 62 KGNSDISVGNVIGSNIANIGMVLGISGLFY--PILIRKSTLRFDYFITVLVTLLFYAVSY 119
Query: 188 DGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
+G I+ +E ++L L+ + FN + F D+ A + V + + V
Sbjct: 120 NGMIELWEGILLFSLF-----IGFN-LYLFKYTDQGLAEGSEGEEEVE-QVKGYSWLVAI 172
Query: 248 GIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIM 307
+ G + G+ + A+ K F + E V+G+T +A G LPE + +
Sbjct: 173 SLFLGGIVG---LYIGSELLVNNAV--KISREFGVSERVIGITIIAIGTSLPELITSIMA 227
Query: 308 SRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+ + + + N LG+N + +L LG+ +I+ + +
Sbjct: 228 ALSKKTDMAIGNILGSNIMNVLSILGITAIIKPIGV 263
Score = 39.5 bits (88), Expect = 0.16
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I + + + V T +++ TS PE ++++ ++DM IG I+GS + N
Sbjct: 196 ISREFGVSERVIGITIIAIGTSLPELITSIMAALSKKTDMAIGNILGSNIMN--VLSILG 253
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLV--AFVWDGQIDWFEAMVLGILYILY 206
PI + + D L +M+ ++++ +I + E ++L I Y Y
Sbjct: 254 ITAIIKPIGVSDEFLQSDFL-WMIGFTLILFPLIRTKMRISFIEGLILLIGYCTY 307
>UniRef50_Q66S42 Cluster: Sodium/calcium exchanger protein-like
protein; n=1; Oikopleura dioica|Rep: Sodium/calcium
exchanger protein-like protein - Oikopleura dioica
(Tunicate)
Length = 557
Score = 50.8 bits (116), Expect = 7e-05
Identities = 35/144 (24%), Positives = 69/144 (47%), Gaps = 24/144 (16%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
G +LY ++ ++ F L +V + +F+P + I LK+ +NVA T ++ T+ +F+
Sbjct: 73 GMNILYSLWCLWLFIALGLVADAFFVPNLTKISSQLKLSENVAGVTLVAFGTALQTYFLQ 132
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
+ L S+ P + RP+ RDV+ Y+ ++ L
Sbjct: 133 SPALVLVYSN------------------------SIRPFSPAARPLLRDVIFYLWSLYWL 168
Query: 183 VAFVWDGQIDWFEAMVLGILYILY 206
+ ++ G+I+ F+A+ +LYI+Y
Sbjct: 169 LQCLYKGRIEMFDAVGFIVLYIIY 192
Score = 37.1 bits (82), Expect = 0.87
Identities = 31/131 (23%), Positives = 57/131 (43%), Gaps = 4/131 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G + I VMG+TFLA+ + + + +SR G+ G V+ G+ L +L G+
Sbjct: 428 GFFWKINNVVMGLTFLAWANSIGDLVADLGLSRIGKAGTAVAACFGSPLLNLLVGTGIGC 487
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I S + + + + A ++L I K+ + R +GI +L
Sbjct: 488 TISIASNDWEAIDLDLRPLEVA----LLGSTTVVLLCLLVILPIIKYNVGRALGIFQIVL 543
Query: 397 YVVFIVFAILV 407
Y+ +V +L+
Sbjct: 544 YIGGLVLCVLL 554
>UniRef50_A1CD75 Cluster: Sodium/calcium exchanger protein; n=6;
Trichocomaceae|Rep: Sodium/calcium exchanger protein -
Aspergillus clavatus
Length = 994
Score = 50.8 bits (116), Expect = 7e-05
Identities = 28/147 (19%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
AF++ +++ F+ + I +D+ + + L + +++ TF++ P+ F
Sbjct: 113 AFIILILWLSLLFSTIGIAASDFLCIDLSTLASILGMSESLTGVTFLAFGNGSPDVFSTF 172
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ + IG ++G+A F P + R RDV +++ +S +
Sbjct: 173 AAMRSNSGSLAIGELLGAASF--ITSVVAGSMALVQPFKVARRSFVRDVGYFVIAVSFSM 230
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
+ DG++ +E+ + LY Y V++
Sbjct: 231 VLLADGRLHVWESAAMVGLYCFYVVLV 257
Score = 38.7 bits (86), Expect = 0.28
Identities = 20/56 (35%), Positives = 27/56 (48%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
ES+ G+TFLAFG P+ S F R G + + LGA S G L++
Sbjct: 151 ESLTGVTFLAFGNGSPDVFSTFAAMRSNSGSLAIGELLGAASFITSVVAGSMALVQ 206
>UniRef50_Q7MVL3 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=8; Bacteroidales|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 317
Score = 50.4 bits (115), Expect = 9e-05
Identities = 65/320 (20%), Positives = 126/320 (39%), Gaps = 40/320 (12%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I + ++ V T ++ TS PE V++++ +D+ IG ++GS +FN
Sbjct: 29 IAKRFRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVIGSNIFNILAIVGIT 88
Query: 154 X-------XXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
I I + ++ VL +M N L + I E VL ++++
Sbjct: 89 ALIMPLTMSNSTIRIEIPLTILSSAVLFFMAN-DRLFDMAGENVITRTEGFVLLAFFLIF 147
Query: 207 FVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTM 266
FN K ++ + + S+ + V G+ F V N +
Sbjct: 148 LFYTFNMSKGEESPGQV------RQFALPLSI----IMVIGGLVALVFGGDLFVDNAAML 197
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
+ + ESV+ +T +A G LPE + + + + G+ + N +G+N
Sbjct: 198 AGRMGVS----------ESVVAITIVAGGTSLPELVTTLVAAIKKRPGMAIGNIVGSNLF 247
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLR 386
IL LG+ I + ++ + + I SA + + LF G T++
Sbjct: 248 NILLILGVSSSISPIRIQGITVVDYGIFILSAILLYVFG------------LFFGDKTIK 295
Query: 387 RTVGIVLGILYVVFIVFAIL 406
R G +L L++ + V+ ++
Sbjct: 296 RFEGSILLSLFICYTVYLVM 315
Score = 50.0 bits (114), Expect = 1e-04
Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 7/155 (4%)
Query: 59 QLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPE 118
Q+RQ A L ++ I L + D F+ ++ + + ++V A T ++ TS PE
Sbjct: 163 QVRQFALPLSIIMVIGGLVAL-VFGGDLFVDNAAMLAGRMGVSESVVAITIVAGGTSLPE 221
Query: 119 FFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVN 178
+++ M IG IVGS LFN +PI I V D I++++
Sbjct: 222 LVTTLVAAIKKRPGMAIGNIVGSNLFN--ILLILGVSSSISPIRIQGITVV-DYGIFILS 278
Query: 179 ISVLVA---FVWDGQIDWFEAMVLGILYILYFVVM 210
+L F D I FE +L L+I Y V +
Sbjct: 279 AILLYVFGLFFGDKTIKRFEGSILLSLFICYTVYL 313
Score = 44.4 bits (100), Expect = 0.006
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + + V+G+T LAFG PE + + +G I + N +G+N IL +G+ LI
Sbjct: 33 FRLSDLVIGLTVLAFGTSAPELTVSLMAALKGSADIAIGNVIGSNIFNILAIVGITALIM 92
Query: 340 --TVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILY 397
T+S E +++SA + F + G+ + RT G VL +
Sbjct: 93 PLTMSNSTIRIEIPLTILSSAVLFFMANDR--------LFDMAGENVITRTEGFVLLAFF 144
Query: 398 VVFIVFAILVELG 410
++F+ + + G
Sbjct: 145 LIFLFYTFNMSKG 157
>UniRef50_Q4APH1 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein precursor; n=2; Chlorobiaceae|Rep:
K+-dependent Na+/Ca+ exchanger related-protein precursor
- Chlorobium phaeobacteroides BS1
Length = 325
Score = 50.4 bits (115), Expect = 9e-05
Identities = 54/279 (19%), Positives = 115/279 (41%), Gaps = 14/279 (5%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
++ TLL + ++ + + +L + V T ++ TS PE +N++
Sbjct: 9 VFGLTLL-LGGGNFLVTGASAMARNLGVSPLVIGLTVVAFGTSAPELSINLLGALQGNGG 67
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+ G I+GS + N P+ I+ ++R++ + M+ IS++ V
Sbjct: 68 ISFGNIIGSNIANIGLVLGLTALIR--PLTIESLIISREIPM-MILISIITLIVGSDVFL 124
Query: 193 WFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNK 252
+ L +++F + + D + K+ + + + S G+ +
Sbjct: 125 RSSPDIFDRSDGLVLLMLFGVFMYYTIGDVLK----KRRDSLIEEAEE--FSGGRGLRDT 178
Query: 253 GFNDPSPVTN--GTTMTEKPAIDEKNG--HTFFIPESVMGMTFLAFGGCLPEACSIFIMS 308
N V G + K ++D G IP+ ++G+T +A G LPE + + +
Sbjct: 179 VLNLVMFVGGLAGLLLGGKLSVDAAVGIAEALEIPQVIIGLTVVAIGTSLPELVTSLVAT 238
Query: 309 RRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQG 347
+G+ I V N +G+N +L G+ I +++ + G
Sbjct: 239 FQGKTDIAVGNVVGSNIFNLLLVNGVCSSITQIAVPVNG 277
>UniRef50_A7HW03 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
- Parvibaculum lavamentivorans DS-1
Length = 334
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ +V T ++V TS PE +V++ F +SD+ IG +VGS +FN
Sbjct: 223 VSDSVIGLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPV 282
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDG-QIDWFEAMVLGILYILYFVVM 210
P+ D+ D+ + + + F W G +I EA++L Y Y V+
Sbjct: 283 PVPADIAGF--DIWVMGAASLLFLVFAWTGSRIGRVEALLLLGGYGAYVTVL 332
Score = 46.0 bits (104), Expect = 0.002
Identities = 46/234 (19%), Positives = 97/234 (41%), Gaps = 9/234 (3%)
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP 167
T + TS PE ++ F + +G +VGS + N P+ +D
Sbjct: 58 TLVGFGTSAPELVASLEGAFQGYPGIAVGNVVGSNIANILLILGIAGLIF--PMTVDRGA 115
Query: 168 VTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAAC 227
+ RD + + ++++ G + + LG L +L +++ L D
Sbjct: 116 LKRDGSMMLGAAAIMMGACLYGVLS--REVGLGFLALLSVYLIYTYRADRRLQDGTAKLH 173
Query: 228 CKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVM 287
+ +T++ ++ VE + G + G ++ A++ H + +SV+
Sbjct: 174 AGEAEFLTSTGPKTSLLVEIVMALGGL---VALVTGASLLVDAAVEIATRHG--VSDSVI 228
Query: 288 GMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
G+T +A G LPE + + + R + I + N +G+N +L G+ +++ V
Sbjct: 229 GLTLVAVGTSLPEVATSVLAAFRRQSDIAIGNVVGSNIFNVLGIAGMVAVVKPV 282
Score = 37.5 bits (83), Expect = 0.66
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
++G+T + FG PE + + +G GI V N +G+N IL LG+ LI ++++
Sbjct: 54 LIGLTLVGFGTSAPELVASLEGAFQGYPGIAVGNVVGSNIANILLILGIAGLIFPMTVD- 112
Query: 346 QGA--ENTAVLINSAGI 360
+GA + ++++ +A I
Sbjct: 113 RGALKRDGSMMLGAAAI 129
>UniRef50_A3W9R9 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=2; Erythrobacter|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Erythrobacter sp.
NAP1
Length = 328
Score = 49.6 bits (113), Expect = 2e-04
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 26/271 (9%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I E L + + ATS PE +V ++ ++ G IVGS L N
Sbjct: 29 IAEKLGVSTLFTGLVIVGFATSMPEMVASVQASLAGSPEIAWGNIVGSNLANTLLILGVS 88
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQ-IDWFE-AMVLGILYILYFVVMF 211
PIA+ + RD ++ + +L A W W A++ GIL +Y V +
Sbjct: 89 ALVM--PIAL-IGTGRRDAVVALGVTLLLWALAWSQLGARWIGFALLAGIL--VYIVWRY 143
Query: 212 NSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPA 271
A + ++ K G+ + V + GI G N + VT ++
Sbjct: 144 RHPGAASIEEE---DSSDKPTGIVVASALFLVGL--GILVAGGN--ALVTGAISLAT--- 193
Query: 272 IDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFA 331
F +PE+V+G+T +A G LPE + + RG+ G+ + N LG+N IL
Sbjct: 194 -------IFKVPETVIGLTVVAIGTSLPELAASIAAALRGKSGLAIGNVLGSNIYNILLI 246
Query: 332 LGLPWLIRTVSL--EIQGAENTAVLINSAGI 360
G I +L E+ G + + ++ G+
Sbjct: 247 GGATMSIAPFALPQELVGLQMALLTASAVGL 277
Score = 39.5 bits (88), Expect = 0.16
Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 99 KIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXX 158
K+P+ V T +++ TS PE ++ + +S + IG ++GS ++N
Sbjct: 196 KVPETVIGLTVVAIGTSLPELAASIAAALRGKSGLAIGNVLGSNIYN--ILLIGGATMSI 253
Query: 159 TPIAIDMRPVTRDVLIYMVNISVLVAFVW 187
P A+ V + + + L+A +W
Sbjct: 254 APFALPQELVGLQMALLTASAVGLLAVLW 282
>UniRef50_A0R1H4 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=2; Mycobacterium|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 335
Score = 49.6 bits (113), Expect = 2e-04
Identities = 51/249 (20%), Positives = 98/249 (39%), Gaps = 6/249 (2%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
V T +S+ TS PE V V + + +G I G+ N P+AI
Sbjct: 39 VVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLSALLR--PLAI 96
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS--MKAFVLID 221
R + D+ + V + DG + + ++L + Y VV+ S +++ ++D
Sbjct: 97 QRRTLRLDLPVMAVAAVLFWVLCIDGTLSRVDGVILLCAAVAYTVVVVRSARVESRDVVD 156
Query: 222 KIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNG--HT 279
+ A + G + + G + F + ++ G
Sbjct: 157 EYAYAYRGEPAGDDGAAEREPDMPDTGSLVRYFAMTIVGITVVVVGADWLVEGAVGIARE 216
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + ++++G+T +A G PE + + + RGE I + N LG++ I+ LG L+
Sbjct: 217 FGVSDALIGLTIVAIGTSAPELVTTIVSTVRGERDIAIGNLLGSSVYNIVLILGATCLVP 276
Query: 340 TVSLEIQGA 348
L + +
Sbjct: 277 ADGLPLNSS 285
Score = 47.2 bits (107), Expect = 8e-04
Identities = 29/149 (19%), Positives = 65/149 (43%), Gaps = 2/149 (1%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
G+ + Y I T++ +V D+ + I + + + T +++ TS PE
Sbjct: 183 GSLVRYFAMTIVGITVV-VVGADWLVEGAVGIAREFGVSDALIGLTIVAIGTSAPELVTT 241
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
++ST E D+ IG ++GS+++N + ++ V D+ + +V +L
Sbjct: 242 IVSTVRGERDIAIGNLLGSSVYNIVLILGATCLVPADGLPLNSSLVWIDIPVMVVATLLL 301
Query: 183 VAFVWDG-QIDWFEAMVLGILYILYFVVM 210
+ + G ++ E + + Y+ Y +
Sbjct: 302 IPVFFSGRRVHRAEGGAMVVAYLAYLTFL 330
Score = 45.6 bits (103), Expect = 0.002
Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 17/132 (12%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
V+GMT ++ G LPE + G G + V N G N++ +LF LGL L+R ++++
Sbjct: 39 VVGMTVVSIGTSLPELAVGVTAATEGSGALAVGNIAGTNTVNLLFILGLSALLRPLAIQR 98
Query: 346 QGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVL---GILYVVFIV 402
+ ++ A + F W++ G TL R G++L + Y V +V
Sbjct: 99 RTLRLDLPVMAVAAVLF------------WVLCIDG--TLSRVDGVILLCAAVAYTVVVV 144
Query: 403 FAILVELGIIFD 414
+ VE + D
Sbjct: 145 RSARVESRDVVD 156
>UniRef50_UPI0000E4891C Cluster: PREDICTED: similar to K-dependent
Na/Ca exchanger NCKX4, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to K-dependent Na/Ca
exchanger NCKX4, partial - Strongylocentrotus
purpuratus
Length = 76
Score = 49.2 bits (112), Expect = 2e-04
Identities = 19/50 (38%), Positives = 31/50 (62%)
Query: 47 IDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICE 96
I FP G+FT+EQ + GA ++ + +Y + VC YF+P +E++CE
Sbjct: 27 ISKFPRGVFTNEQRKGGALVVNFLVSLYLCGAIGYVCAAYFVPSLEILCE 76
>UniRef50_Q9SYG9 Cluster: F15I1.21 protein; n=9; Magnoliophyta|Rep:
F15I1.21 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 644
Score = 49.2 bits (112), Expect = 2e-04
Identities = 32/152 (21%), Positives = 70/152 (46%), Gaps = 7/152 (4%)
Query: 61 RQGAFLLYVVFGIYTFTLLAIVCN---DYFIPCVELICEDLKIPQNVAAATFMSVATSCP 117
R L Y++ G++ L ++ N DYF +E + + L++P VA T + + P
Sbjct: 130 RDFKILGYILLGVWLVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAP 189
Query: 118 EFFVNVISTFL--TESDMGIGTIVGSALF-NXXXXXXXXXXXXXTPIAIDMRPVTRDVLI 174
+ F + I+ F+ + ++G+ +++G A+F + ID + RD+
Sbjct: 190 DVFAS-IAAFVGSDKGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSF 248
Query: 175 YMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
++ + L+ + G++ A+ +Y+ Y
Sbjct: 249 FLFTLVALMVILMVGKVTVGIAIAFVSIYVFY 280
>UniRef50_Q5LMC5 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=17; Rhodobacterales|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Silicibacter
pomeroyi
Length = 319
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Query: 93 LICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXX 152
+I + + V T ++V TS PE V++ ++D+ +G ++GS +FN
Sbjct: 201 IIARTYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNMFNLLAIIGV 260
Query: 153 XXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV---WDGQIDWFEAMVLGILYILYFVV 209
PI +D + D+ + + +L+ FV WD W + L +Y++Y VV
Sbjct: 261 ATMFG--PIPVDPEFLRFDLWVMLAASLLLIPFVFFKWDITRTW--GVFLTGIYLVYIVV 316
Query: 210 M 210
+
Sbjct: 317 V 317
Score = 40.3 bits (90), Expect = 0.093
Identities = 23/81 (28%), Positives = 37/81 (45%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+P ++ +T +AFG PE GI + N +G+N+ IL LG+P L+ T+
Sbjct: 34 VPALIVSLTIVAFGTSAPELLISIKAVLEHAPGIALGNVVGSNTANILLVLGVPALLATL 93
Query: 342 SLEIQGAENTAVLINSAGIDF 362
VL+ A + F
Sbjct: 94 HTSECNTRRNYVLMILASVLF 114
Score = 40.3 bits (90), Expect = 0.093
Identities = 16/66 (24%), Positives = 37/66 (56%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
T+ + E+V+G+T +A G LPE + + + R + + + N +G+N +L +G+ +
Sbjct: 205 TYGVSETVIGLTLVAVGTSLPELATTVMAALRRQADVALGNVIGSNMFNLLAIIGVATMF 264
Query: 339 RTVSLE 344
+ ++
Sbjct: 265 GPIPVD 270
>UniRef50_A7C0J3 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Beggiatoa sp. PS|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Beggiatoa sp. PS
Length = 253
Score = 48.8 bits (111), Expect = 3e-04
Identities = 23/67 (34%), Positives = 39/67 (58%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
I E ++ +T ++ G LPE ++ I + RGE + V N +G+N IL LGL L+ +
Sbjct: 98 ISELIIALTVISIGTSLPELATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPI 157
Query: 342 SLEIQGA 348
S+++ A
Sbjct: 158 SIDVSQA 164
Score = 48.4 bits (110), Expect = 4e-04
Identities = 34/154 (22%), Positives = 68/154 (44%), Gaps = 1/154 (0%)
Query: 58 EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCP 117
E+ R +L +VF + LL + +++ + +I + I + + A T +S+ TS P
Sbjct: 57 EKNRHLHIILQLVFIVAGLGLL-VQGSNWLVNGAIVIAQFYGISELIIALTVISIGTSLP 115
Query: 118 EFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV 177
E +I TF E ++ +G +VGS +FN I + + D+ + +
Sbjct: 116 ELATVIIGTFRGEQELVVGNVVGSNIFNILLVLGLTTLVSPISIDVSQAAIFLDMPVMIA 175
Query: 178 NISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
+ ++ I+ +E + YI Y + +F
Sbjct: 176 VAIACLPIFFNNLIERWEGGLFLAYYIAYTLYLF 209
>UniRef50_A6F7Z5 Cluster: Putative uncharacterized protein; n=1;
Moritella sp. PE36|Rep: Putative uncharacterized protein
- Moritella sp. PE36
Length = 340
Score = 48.8 bits (111), Expect = 3e-04
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 2/151 (1%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
LL + + +L V D I + + + T ++ TS PE V+ I+
Sbjct: 3 LLLPIIAVLVGFILLTVSADRLILVSSTLAKQFGVSVMFIGMTVIAFGTSFPELVVSAIA 62
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+F + +G +GS + N P+ I +R + R++ I + + +A
Sbjct: 63 SFNGAEGLAVGNAIGSNIIN--CGLVLALCALFMPLVIKVRFIKRELPILVFALIATIAL 120
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMKA 216
+ +G I +++++L +L LY V + S A
Sbjct: 121 MSNGSITMWDSLILILLLALYCVYLAKSSSA 151
Score = 39.5 bits (88), Expect = 0.16
Identities = 19/57 (33%), Positives = 31/57 (54%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+ + ++G+T +AFG LPE + RRG I + +G+N+ +L L P LI
Sbjct: 199 VSDLLIGLTIVAFGTSLPELAAAIAGVRRGMPEIAFATVIGSNTFNLLGVLAFPGLI 255
Score = 37.5 bits (83), Expect = 0.66
Identities = 21/67 (31%), Positives = 33/67 (49%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + +GMT +AFG PE I S G G+ V NA+G+N + L L L
Sbjct: 35 FGVSVMFIGMTVIAFGTSFPELVVSAIASFNGAEGLAVGNAIGSNIINCGLVLALCALFM 94
Query: 340 TVSLEIQ 346
+ ++++
Sbjct: 95 PLVIKVR 101
>UniRef50_A4VIA6 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=5; Bacteria|Rep: K+-dependent Na+/Ca+
exchanger related-protein - Pseudomonas stutzeri (strain
A1501)
Length = 361
Score = 48.8 bits (111), Expect = 3e-04
Identities = 63/316 (19%), Positives = 121/316 (38%), Gaps = 28/316 (8%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
IP + T ++ TS PE V+V ++ D+ +G ++GS + N
Sbjct: 36 IPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALIA-- 93
Query: 160 PIAIDMRPVTRDVLIYMVNISVLV-AFVWDGQIDWFEAMVLGIL---YILYFVVMFNSMK 215
P+ + + + DV + M+ +L A W+G I + +L I Y L+ V K
Sbjct: 94 PLVVSRQLIRLDVPV-MIGAGLLCYALAWNGSISRLDGALLLISLIGYTLFLVAASKREK 152
Query: 216 AFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEK 275
A D+ + + + + G+ + G+ + + A+
Sbjct: 153 APAGDDEFATEFGPDESDKPFAWVFQLLLILLGL--------GLLVGGSNLLIEGAVGL- 203
Query: 276 NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
+ E V+G+T +A G +PE + + +GE I V N +G+ +L LG
Sbjct: 204 -ARALGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLVLGAG 262
Query: 336 WLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGI 395
+ L I N+ DF + +F + +RR G++
Sbjct: 263 AAVAPGGLSISP--------NAQSFDF---PVMLAVFVACLPIFFSGYCIRRWEGLLFFA 311
Query: 396 LYVVFIVFAILVELGI 411
YV + ++ ++ G+
Sbjct: 312 YYVAYTLYLVMFATGL 327
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/59 (42%), Positives = 31/59 (52%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F IP ++G+T +AFG PE S G G I V N +G+N IL LGL LI
Sbjct: 34 FGIPPLIIGLTVVAFGTSAPETAVSVQASLGGSGDIAVGNVIGSNIANILLILGLSALI 92
Score = 41.5 bits (93), Expect = 0.040
Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L + + V T ++V TS PE +V++ E D+ +G +VGS +FN
Sbjct: 207 LGLSELVIGLTVVAVGTSMPELATSVLAVIKGERDIAVGNVVGSCIFNLLLVLGAGAAVA 266
Query: 158 XTPIAIDMRPVTRDVLIYM-VNISVLVAFVWDGQIDWFEAMVLGILYILY--FVVMF 211
++I + D + + V ++ L F I +E ++ Y+ Y ++VMF
Sbjct: 267 PGGLSISPNAQSFDFPVMLAVFVACLPIFFSGYCIRRWEGLLFFAYYVAYTLYLVMF 323
>UniRef50_A4GJC5 Cluster: K+-dependent Na+/Ca+ antiporter; n=1;
uncultured marine bacterium EB0_49D07|Rep: K+-dependent
Na+/Ca+ antiporter - uncultured marine bacterium
EB0_49D07
Length = 313
Score = 48.8 bits (111), Expect = 3e-04
Identities = 56/257 (21%), Positives = 105/257 (40%), Gaps = 25/257 (9%)
Query: 87 FIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNX 146
F+ +I + + I V T ++ TS PE FV + S ++ +GT +GS + N
Sbjct: 24 FVDHASVIAKHMGISDLVIGLTLIAFGTSAPEIFVGISSIINQNEEIALGTAIGSNISNI 83
Query: 147 XXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
P + + + + +++ +L + DG+I + E+M G + IL
Sbjct: 84 ALIFGVSCLYLTEPSKTQLW----NFVPFGLSVVLLGLTLVDGKISFNESM--GFVGIL- 136
Query: 207 FVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTM 266
+ MF K L ++ SL N I G + G +
Sbjct: 137 MIFMFVLFKTDGLAEE-------------DSLESNEFGRSLFISLIGL---VALIAGANI 180
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
+ A E +P+ ++G+T +A G LPE + + R+G+ + V N +G+N
Sbjct: 181 SVVYA--ENTALLLGVPQLIIGLTIIALGTSLPELAATIVALRKGKHQMVVGNIIGSNVF 238
Query: 327 AILFALGLPWLIRTVSL 343
++F + + +V L
Sbjct: 239 NLVFIIPMIGFFGSVEL 255
>UniRef50_A3CSD7 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Methanoculleus marisnigri JR1|Rep: Na+/Ca+ antiporter,
CaCA family - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 311
Score = 48.8 bits (111), Expect = 3e-04
Identities = 23/64 (35%), Positives = 37/64 (57%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F IP V+G++ +A G LPE + + + R EG I + N LG+N +L LG+ L+
Sbjct: 196 FGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFNLLLVLGISLLLA 255
Query: 340 TVSL 343
V++
Sbjct: 256 PVTV 259
Score = 40.3 bits (90), Expect = 0.093
Identities = 23/77 (29%), Positives = 37/77 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
I +++G T +AFG LPE + G GI + N +G+N + L L IR
Sbjct: 35 ISPALIGSTIIAFGTSLPELVVSTNAAVTGNSGIALGNVIGSNIANVALVLALCTFIRPG 94
Query: 342 SLEIQGAENTAVLINSA 358
+ GA A++ ++A
Sbjct: 95 MVAASGASRPALVRHTA 111
Score = 37.5 bits (83), Expect = 0.66
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ E IP V + ++V TS PE ++++ E + IG I+GS +FN
Sbjct: 192 LAEAFGIPAFVIGVSVVAVGTSLPELATSIVAAARDEGSISIGNILGSNIFN 243
>UniRef50_O66480 Cluster: Putative uncharacterized protein; n=1;
Aquifex aeolicus|Rep: Putative uncharacterized protein -
Aquifex aeolicus
Length = 322
Score = 48.4 bits (110), Expect = 4e-04
Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 6/147 (4%)
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
+Y + G+ +L A D+ + + + L + + V +++ TS PE F + +S
Sbjct: 176 IYFILGLTGLSLGA----DWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELFASAVSA 231
Query: 127 FLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
+ D+ +G + GS +FN P+ + V VL ++ + +L++ +
Sbjct: 232 YKGNPDIALGNVAGSNIFNATLVLGTSSVIRDIPVP-ERANVDLGVL-FIATLLLLISSI 289
Query: 187 WDGQIDWFEAMVLGILYILYFVVMFNS 213
W + + M GI + YF+ + S
Sbjct: 290 WGKRKYTLDRMEGGIFLLAYFIYVIAS 316
Score = 46.4 bits (105), Expect = 0.001
Identities = 24/64 (37%), Positives = 37/64 (57%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F IPE V+G+T +AFG LPE + + GI + N +G+N IL LG+ LI+
Sbjct: 33 FGIPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGISLGNVIGSNIANILLILGVASLIK 92
Query: 340 TVSL 343
+++
Sbjct: 93 PLTV 96
Score = 40.7 bits (91), Expect = 0.071
Identities = 50/259 (19%), Positives = 99/259 (38%), Gaps = 20/259 (7%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
IP+ V T ++ TS PEF VNV + S + +G ++GS + N
Sbjct: 35 IPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGISLGNVIGSNIAN--ILLILGVASLIK 92
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL----GILYILYFVVMFNSMK 215
P+ + V +++ + L+ D ++ ++ G++ I+ F+ +
Sbjct: 93 PLTVHATFVKKEIPVNFFLTLTLIVMANDVILNHAPVSLISRGDGLVLIITFLGYMYFLV 152
Query: 216 AFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEK 275
A++ D I K+ + S + G+ V + + + E
Sbjct: 153 AYLERDSILEGEMKE----SISPFKGFIYFILGLTGLSLGADWTVDGAVGLAKALGVSE- 207
Query: 276 NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
+V+G+ +A G LPE + + + +G I + N G+N LG
Sbjct: 208 ---------AVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAGSNIFNATLVLGTS 258
Query: 336 WLIRTVSLEIQGAENTAVL 354
+IR + + + + VL
Sbjct: 259 SVIRDIPVPERANVDLGVL 277
>UniRef50_A0EBJ8 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_88,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 601
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/159 (18%), Positives = 72/159 (45%), Gaps = 1/159 (0%)
Query: 54 IFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVA 113
I ++ ++Q ++ G + ++ V +Y IP +E + +I + +A T ++
Sbjct: 60 IMVNQYMKQTTLIVSGFVGYLVYNGISEVIKEYLIPSLEAVKVRFEISEIMAGVTLLAFG 119
Query: 114 TSCPEFFVNVI-STFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDV 172
+ ++ S++ D IG +G+ F + I ++ R+V
Sbjct: 120 NGAGDVLTALVASSYPGGIDYNIGATMGAGFFLCSIGVYLITKTSKSQIKMEPVHFWRNV 179
Query: 173 LIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
+++I V++ F GQI +F ++ L +LY++ +++
Sbjct: 180 GFQIISIFVIMVFGVIGQISYFSSISLTVLYLILVSLVY 218
>UniRef50_A1SUM2 Cluster: Na+/Ca+ antiporter, CaCA family protein
precursor; n=3; Gammaproteobacteria|Rep: Na+/Ca+
antiporter, CaCA family protein precursor - Psychromonas
ingrahamii (strain 37)
Length = 320
Score = 48.0 bits (109), Expect = 5e-04
Identities = 52/232 (22%), Positives = 97/232 (41%), Gaps = 13/232 (5%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
++ + TS PE V+V + + D+ IG +VGS + N TP+A+
Sbjct: 38 LSGLVIVGFGTSAPELVVSVNAAIEGQPDIAIGNVVGSNIGNILLILGICAVI--TPLAV 95
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLID-K 222
+ RD + + + V + +A + + + Y V + S + +
Sbjct: 96 KPLVLRRDAATVVAASILFLILVGGSALGRADATIFLVAMVSYLVWAYWSERFHAAPSGE 155
Query: 223 IWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFI 282
++ A ++ + S+ ++V G+ + G+ + AI H F +
Sbjct: 156 LYQAEAEELSATPKSVLWTIIAVVLGL--------LLLIGGSQVLLIGAIGIAE-H-FNV 205
Query: 283 PESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
PE+V+G+T +A G LPE I + R + V N LG+N +L LG+
Sbjct: 206 PEAVIGLTLVAIGTSLPELSISVIAAIRRHADVAVGNILGSNIFNLLGILGV 257
Score = 47.6 bits (108), Expect = 6e-04
Identities = 33/147 (22%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L+ + + LL I + + I E +P+ V T +++ TS PE ++VI+
Sbjct: 171 VLWTIIAVVLGLLLLIGGSQVLLIGAIGIAEHFNVPEAVIGLTLVAIGTSLPELSISVIA 230
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+D+ +G I+GS +FN P+ + R + D + + +L F
Sbjct: 231 AIRRHADVAVGNILGSNIFN--LLGILGVSSFLQPLPVHARILQFDQWVMLGTSLLLFLF 288
Query: 186 VWDG-QIDWFEAMVLGILYILYFVVMF 211
++ G ++ E +L Y +Y + F
Sbjct: 289 LYTGSRLSRLEGGILLGGYCIYIWLSF 315
>UniRef50_A1AXB5 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
n=2; sulfur-oxidizing symbionts|Rep: Na+/Ca+ antiporter,
CaCA family precursor - Ruthia magnifica subsp.
Calyptogena magnifica
Length = 317
Score = 48.0 bits (109), Expect = 5e-04
Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 2/150 (1%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L + + + +L I D F I KI + TS PE V+ ++
Sbjct: 4 ILLPIIALLSGFVLLIWSADKFTENGTKIANIFKISPLIIGLIIFGFGTSTPEMLVSALA 63
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ + IG +GS +FN +PI + ++ L MV L
Sbjct: 64 AIEGNTGLSIGNAIGSNIFN--ISLVLGISAIISPIEVQGDVFKKEWLFLMVVTLCLGLL 121
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMFNSMK 215
+WD ++D+ + M+L L +L+F K
Sbjct: 122 LWDYRLDFTDGMILLSLLVLFFAYTIKQAK 151
Score = 38.7 bits (86), Expect = 0.28
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 275 KNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
K + F I ++G+ FG PE + + G G+ + NA+G+N I LG+
Sbjct: 31 KIANIFKISPLIIGLIIFGFGTSTPEMLVSALAAIEGNTGLSIGNAIGSNIFNISLVLGI 90
Query: 335 PWLIRTVSLEIQG 347
+I + E+QG
Sbjct: 91 SAIISPI--EVQG 101
Score = 34.7 bits (76), Expect = 4.6
Identities = 22/110 (20%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
+ + +++ T PE V++ S + M IG ++GS LFN + + +
Sbjct: 208 IIGLSVVALGTGLPELAVSITSVLKKQYAMVIGNVIGSNLFNTIAVLAIPGLIHPSDVPV 267
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQ--IDWFEAMVLGILYILYFVVMF 211
++ V++ + + +V++ ++ + I+ F+ VL ++ LY +F
Sbjct: 268 EVISRDYPVMLLLTILLFIVSYKFNKKHIINRFKGFVLIGMFGLYIWQLF 317
>UniRef50_Q4Z7F0 Cluster: Calcium antiporter, putative; n=5;
Plasmodium (Vinckeia)|Rep: Calcium antiporter, putative
- Plasmodium berghei
Length = 440
Score = 48.0 bits (109), Expect = 5e-04
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 54 IFTDEQLRQGAFLLYVVFG---IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFM 110
+F D+++ + L V+ G + T L V ++Y I VE + I +N +
Sbjct: 275 LFQDKEMTEETPQLSVITGSLFLIIITFLVSVHSEYLINTVESVVRYYNISENFIGVILL 334
Query: 111 SVATSCPEFFVNVISTFLTESDMGIGTIVGS----ALFNXXXXXXXXXXXXXTPIAIDMR 166
+ + E V + D+ +G VGS ALF P+ +
Sbjct: 335 PIVGNATEHLTAVTVAIKNKVDLTMGVAVGSSAQIALF-VVPITVLFGWILNKPMTLAFS 393
Query: 167 PVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
P++ +L+ +++ V +A V DG+ +W E ++L Y++ VV +
Sbjct: 394 PLSSVILV--ISVIVTMAIVQDGESNWLEGVLLITAYLIVGVVFW 436
>UniRef50_O51186 Cluster: Na+/Ca+ exchange protein, putative; n=3;
Borrelia burgdorferi group|Rep: Na+/Ca+ exchange
protein, putative - Borrelia burgdorferi (Lyme disease
spirochete)
Length = 337
Score = 47.6 bits (108), Expect = 6e-04
Identities = 56/284 (19%), Positives = 121/284 (42%), Gaps = 21/284 (7%)
Query: 68 YVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF 127
YV FGI+ L + + + I LK+P + T +S +TS PE F ++++ F
Sbjct: 18 YVGFGIF----LLYLGGNLLLKSSVGIATYLKVPTLLIGVTIVSFSTSAPELFTSLVAAF 73
Query: 128 LTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVW 187
++++ + ++GS + N ++ L ++ + +L++F +
Sbjct: 74 KGKNEIVVSNVIGSNIINMLLALPLAGFFLKIKADFKRLKLSFMFLFLLMFLLLLLSFDF 133
Query: 188 DG------QIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDN 241
+ F + + IL++ Y ++ + K + ++ + + + + S N
Sbjct: 134 RSYSFFVTPYNRFSSFSILILFLSYLLLFYKEEKEYASLENSFQ---EGASNLNQSFNFI 190
Query: 242 NVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPE- 300
++ + F + G+ + A+ N + F + E ++G+ +AFG +PE
Sbjct: 191 FFNLLSFAISMYF-----LYLGSKLLVDGALYIAN-NVFNVSEKLIGIILVAFGTSVPEL 244
Query: 301 ACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
S+F + R+ E I N +G+N I F L R + L+
Sbjct: 245 VVSLFAIIRK-ESDIAFGNIIGSNIFNIGFILASSSFFRPILLQ 287
Score = 44.4 bits (100), Expect = 0.006
Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 13/166 (7%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICED--LKIPQNVAAAT------ 108
+ ++GA L F F LL+ + YF+ + D L I NV +
Sbjct: 173 ENSFQEGASNLNQSFNFIFFNLLSFAISMYFLYLGSKLLVDGALYIANNVFNVSEKLIGI 232
Query: 109 -FMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI-DMR 166
++ TS PE V++ + ESD+ G I+GS +FN PI + D+
Sbjct: 233 ILVAFGTSVPELVVSLFAIIRKESDIAFGNIIGSNIFN--IGFILASSSFFRPILLQDIY 290
Query: 167 PVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFN 212
+ +++++ + LV + G +++ +LY LY +++FN
Sbjct: 291 ILDFSIMVFITLVLFLVV-KFKGVFGRGISLIFLLLYFLYNLMLFN 335
>UniRef50_Q0YP53 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=4; Chlorobium|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Chlorobium
ferrooxidans DSM 13031
Length = 318
Score = 47.6 bits (108), Expect = 6e-04
Identities = 63/289 (21%), Positives = 111/289 (38%), Gaps = 27/289 (9%)
Query: 68 YVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTF 127
Y++FGI L A + D F+ I +I + AT + ATS PE V V +
Sbjct: 6 YLLFGI----LFAALGGDLFVRGAVGIASSFRIAPGIIGATVAAFATSTPELSVAVNAGI 61
Query: 128 LTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVW 187
+ +G +GS + N D + RD + ++ + +
Sbjct: 62 AGSPQIAMGDALGSNIVNIAFILGIVLAISGIDAPQD--TIRRDYTVALLVPVITGILLL 119
Query: 188 DGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
DG + + ++ +++ +F+ +F A ++ N N SV
Sbjct: 120 DGLVSRLDGFLMVSIFLFWFLAVFAE-----------ARKQRRKNAEIPEKNKKWASVLL 168
Query: 248 GIDNKGFNDPSPVTNGTTMTE-KPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFI 306
+ VT+G + AI G F+ +G T +A G +PE S I
Sbjct: 169 AVAGLIL----LVTSGKLIVSGATAIALAFGMDKFL----IGATVVALGTSMPELASSLI 220
Query: 307 MSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLI 355
RG +G+ LG+N L +G+ +I + + ++ TA+LI
Sbjct: 221 AKYRGHDEVGLGTILGSNIFNGLLIVGVTAMINPIQVTLR-ETGTALLI 268
Score = 44.8 bits (101), Expect = 0.004
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Query: 107 ATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMR 166
AT +++ TS PE ++I+ + ++G+GTI+GS +FN PI + +R
Sbjct: 203 ATVVALGTSMPELASSLIAKYRGHDEVGLGTILGSNIFN--GLLIVGVTAMINPIQVTLR 260
Query: 167 PVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
T L+ + +L + DG+I + + L +LY Y + F
Sbjct: 261 E-TGTALLIGITALLLTFPLSDGRIKKSQGVFLIMLYAGYLIFCF 304
>UniRef50_Q1YU10 Cluster: Putative Ca2+/Na+ antiporter; n=1; gamma
proteobacterium HTCC2207|Rep: Putative Ca2+/Na+
antiporter - gamma proteobacterium HTCC2207
Length = 330
Score = 47.2 bits (107), Expect = 8e-04
Identities = 53/281 (18%), Positives = 110/281 (39%), Gaps = 17/281 (6%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA LL ++ G+ L + D F+ + I + T +S+ TS PE V+
Sbjct: 2 GAMLLPIL-GLLIGVLGLLWGADRFVEGSAGAARNFGISPLIIGLTVVSIGTSAPEVLVS 60
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
+ + +++ +G +GS + N TP+ + +T++ + +V ++
Sbjct: 61 INAALSNAAELAVGNALGSNMANIGLVLGATLLIAPTPVQKHL--LTQEGAVLLVITAIA 118
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNN 242
++DG + E+ +L L + K V +++ + + D
Sbjct: 119 GFCLYDGYLGRIESAILAGLIFPLVYIAIRYKKTLVSPEEV---------AIGEDIPDIT 169
Query: 243 VSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEAC 302
+ G T + K I + G I E ++G+T +A G LPE
Sbjct: 170 MGAAALWFIVGLAVLLASAEVTVWSAK-TIAQSLG----ISELIIGLTVVAIGTSLPELA 224
Query: 303 SIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+ + + RG I + N G+N ++ + +I +++
Sbjct: 225 ASVVSAMRGHHDIAIGNVFGSNLFNLMLVMPAAGIISPMTI 265
Score = 41.5 bits (93), Expect = 0.040
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 60 LRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEF 119
+ GA L+ + G+ A V + + I + L I + + T +++ TS PE
Sbjct: 168 ITMGAAALWFIVGLAVLLASAEVT----VWSAKTIAQSLGISELIIGLTVVAIGTSLPEL 223
Query: 120 FVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNI 179
+V+S D+ IG + GS LFN +P+ I RD +
Sbjct: 224 AASVVSAMRGHHDIAIGNVFGSNLFN--LMLVMPAAGIISPMTISPMVFNRDFASLAIMT 281
Query: 180 SVLVAFV 186
+L+A V
Sbjct: 282 LLLIAMV 288
>UniRef50_A5Z7N4 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Eubacterium ventriosum ATCC 27560
Length = 339
Score = 47.2 bits (107), Expect = 8e-04
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 5/133 (3%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L ++ + F LL I DYF+ + + L++P V T ++V TS PE V+ +
Sbjct: 4 ILDIILLLVGFVLL-IKGADYFVDGSCAVAKRLRVPSIVIGLTIVAVGTSLPELAVSTFA 62
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ + +G +VGS +FN + + + R++ + ++ ISVL+ F
Sbjct: 63 AVKHSNAIALGNVVGSNIFN--LLMVIGITALFKDMLVKKSILKREMPLLLI-ISVLLIF 119
Query: 186 VWDGQIDWFEAMV 198
+ G I WF ++
Sbjct: 120 L-AGDILWFGGII 131
Score = 44.0 bits (99), Expect = 0.008
Identities = 20/60 (33%), Positives = 35/60 (58%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
E+++G+T +A G LPE + + + +GE + + N +G+N IL LGL I +V +
Sbjct: 226 ETLVGLTIVAMGTSLPELVTSAVAASKGEADLAIGNVVGSNISNILLVLGLSAAISSVGV 285
Score = 36.3 bits (80), Expect = 1.5
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 9/133 (6%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR-- 339
+P V+G+T +A G LPE + + I + N +G+N +L +G+ L +
Sbjct: 37 VPSIVIGLTIVAVGTSLPELAVSTFAAVKHSNAIALGNVVGSNIFNLLMVIGITALFKDM 96
Query: 340 TVSLEIQGAENTAVLINSAGIDFXXXX---XXXXXXXXWIVLFIGKFTL----RRTVGIV 392
V I E +LI S + F I LF T+ R GI+
Sbjct: 97 LVKKSILKREMPLLLIISVLLIFLAGDILWFGGIIKKNNIFLFENGSTMVGNVNRIDGIL 156
Query: 393 LGILYVVFIVFAI 405
L +L+V FI + +
Sbjct: 157 LLVLFVGFIAWTV 169
>UniRef50_A5WHA8 Cluster: Na+/Ca+ antiporter, CaCA family precursor;
n=2; Psychrobacter|Rep: Na+/Ca+ antiporter, CaCA family
precursor - Psychrobacter sp. PRwf-1
Length = 322
Score = 46.8 bits (106), Expect = 0.001
Identities = 51/257 (19%), Positives = 104/257 (40%), Gaps = 18/257 (7%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D FI + +P + + + TS PE V+ ++ F D+ +G GS +
Sbjct: 20 DTFIDGATSLAVRFNMPSFLIGVIILGIGTSAPELVVSALAAFAGSPDLALGNAYGSNII 79
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYI 204
N +PI I + D+++ + ++ + DG + + GI+ +
Sbjct: 80 NITLVLGVTALI--SPILIRSDVIRYDLMLLLAVTALAAIQLVDGNLSRLD----GIVLV 133
Query: 205 LYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGT 264
+ V VL+ +I + ++N L + + E+ K F +
Sbjct: 134 VALVA--------VLLIQILLSL--RSNKDKVELPEQLAAKEQVNVFKSFGTLILGLSLL 183
Query: 265 TMTEKPAI--DEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALG 322
+ + + + + + E ++G+T +A G LPE + +RRGE + + N +G
Sbjct: 184 IASSRAIVWGAVELATLWGMSELLIGLTIVAIGTSLPELVASVAAARRGEHDMALGNVIG 243
Query: 323 ANSLAILFALGLPWLIR 339
+N L +GL +I+
Sbjct: 244 SNLFNTLGVVGLAAIIK 260
Score = 45.6 bits (103), Expect = 0.002
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 108 TFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP 167
T +++ TS PE +V + E DM +G ++GS LFN ID +
Sbjct: 211 TIVAIGTSLPELVASVAAARRGEHDMALGNVIGSNLFNTLGVVGLAAIIKPMQ-HIDPQI 269
Query: 168 VTRDV-LIYMVN----ISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
++RDV ++ MV+ I ++AF G++ +VL + +I Y V++ S
Sbjct: 270 LSRDVMMVGMVSVLLFILAIIAFKRQGEMKHGSGVVLILTFIFYSVLLAKS 320
>UniRef50_A0Z7F5 Cluster: Putative sodium/calcium exchanger protein;
n=1; marine gamma proteobacterium HTCC2080|Rep: Putative
sodium/calcium exchanger protein - marine gamma
proteobacterium HTCC2080
Length = 321
Score = 46.8 bits (106), Expect = 0.001
Identities = 54/274 (19%), Positives = 105/274 (38%), Gaps = 20/274 (7%)
Query: 71 FGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
F + + A+V + D FI + + + T +S+ TS PE V++ +
Sbjct: 5 FAVVVLGIAALVWSADLFIKGAAAVASRFGMSPLIIGMTVVSLGTSAPEILVSLSAAASG 64
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+ +G GS + N +PI + D+ I + + + + DG
Sbjct: 65 AGALAVGNAFGSNIANIGLVLGLTLII--SPILVGRTTAFTDLPILLAIVVLCGWLLRDG 122
Query: 190 QIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGI 249
+ +A +L +LY M ++ + D I + + D ++ G
Sbjct: 123 TLSATDAFILLGALLLYLTRMARHLRMPSINDDI------------SPVEDLPIAQAIGA 170
Query: 250 DNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSR 309
G V G++ A ++ + E V+G+T +A G LPE + + +
Sbjct: 171 FTVGLG----VLIGSSKALVWAA-VNIAESYGVSELVIGLTIIALGTSLPELAASMVSAI 225
Query: 310 RGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+G I + +G+N +L L +P L + L
Sbjct: 226 KGHADIAIGAVVGSNMFNLLIVLAIPGLFSPLEL 259
Score = 42.7 bits (96), Expect = 0.017
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I E + + V T +++ TS PE +++S +D+ IG +VGS +FN
Sbjct: 192 IAESYGVSELVIGLTIIALGTSLPELAASMVSAIKGHADIAIGAVVGSNMFN--LLIVLA 249
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+P+ + + RD+ V + L FV G
Sbjct: 250 IPGLFSPLELSTTDLQRDLGTVFVTTAALAVFVGFG 285
>UniRef50_Q5AKZ6 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 704
Score = 46.8 bits (106), Expect = 0.001
Identities = 34/178 (19%), Positives = 79/178 (44%), Gaps = 5/178 (2%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
I F + I ++Y P + I + LK+P +A T ++ S P+ F + +
Sbjct: 100 ILCFISVGITASEYLCPNLYTISQFLKLPDTLAGLTLLAFGNSSPDVFGTYHAIGSNSLN 159
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+ I ++G++LF P + RD ++Y++ +++V + G++
Sbjct: 160 LAIAELIGASLF--IMTVVVGTIAIIEPFNVPKNLFIRDCMMYIMVFALVVISLIIGELT 217
Query: 193 WFEAMVLGILYILYF-VVMFNSMKAFVLIDKIWAACCKKNNGVTAS--LNDNNVSVEE 247
++L YI+Y + +++ + I+++ + + +N++N SV+E
Sbjct: 218 SIICILLVSCYIIYVGIAIYSHSQKKTRINRLLREQRSRGQYSVENDGINNDNASVDE 275
>UniRef50_Q4IYA1 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein precursor; n=11; Proteobacteria|Rep:
K+-dependent Na+/Ca+ exchanger related-protein precursor
- Azotobacter vinelandii AvOP
Length = 360
Score = 46.4 bits (105), Expect = 0.001
Identities = 23/59 (38%), Positives = 33/59 (55%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F IP ++G+T +AFG PE + G+G I V NA+G+N +L LGL L+
Sbjct: 34 FGIPPLIIGLTVVAFGTSAPEMAVSVRSASGGQGDIAVGNAIGSNIFNVLMILGLSALV 92
Score = 44.0 bits (99), Expect = 0.008
Identities = 21/64 (32%), Positives = 35/64 (54%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ E +G+T +A G LPE + + + +GE I V N +G+N +L LGL L+
Sbjct: 208 LSELAIGLTMVAAGTSLPELATSLVAAIKGERDIAVGNIVGSNIFNLLAVLGLAALVSPA 267
Query: 342 SLEI 345
+E+
Sbjct: 268 PIEV 271
Score = 41.9 bits (94), Expect = 0.031
Identities = 29/133 (21%), Positives = 55/133 (41%), Gaps = 3/133 (2%)
Query: 84 NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSAL 143
+D I + L + + T ++ TS PE ++++ E D+ +G IVGS +
Sbjct: 192 SDLLIDATVTLARALGLSELAIGLTMVAAGTSLPELATSLVAAIKGERDIAVGNIVGSNI 251
Query: 144 FNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISV-LVAFVWDGQIDWFEAMVLGIL 202
FN PI + + D + + + L F+ +I +E ++
Sbjct: 252 FNLLAVLGLAALVSPAPIEVSPNALAFDYPVMIAAAAACLPIFLTGYRIGRWEGLLFFGY 311
Query: 203 YILY--FVVMFNS 213
Y+ Y + V+F S
Sbjct: 312 YLAYGAYQVLFAS 324
Score = 35.9 bits (79), Expect = 2.0
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
IP + T ++ TS PE V+V S + D+ +G +GS +FN
Sbjct: 36 IPPLIIGLTVVAFGTSAPEMAVSVRSASGGQGDIAVGNAIGSNIFN--VLMILGLSALVI 93
Query: 160 PIAIDMRPVTRDVLIYMVNISVL 182
P+ + + + DV + M+ +S+L
Sbjct: 94 PLRVSRQLIRFDVPV-MIGVSLL 115
>UniRef50_A3V6K5 Cluster: Putative sodium/calcium exchanger; n=1;
Loktanella vestfoldensis SKA53|Rep: Putative
sodium/calcium exchanger - Loktanella vestfoldensis
SKA53
Length = 305
Score = 46.4 bits (105), Expect = 0.001
Identities = 31/145 (21%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
Query: 67 LYVVFGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L++ G+ L+ ++ Y + +I + + + + +++ TS PE V++
Sbjct: 159 LWIGGGLTILGLVTVMVGAHYLVQSASIIARQFGVSEAMIGLSIVAIGTSLPELATTVMA 218
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
E D+ +G IVGS +FN TPI +D R + D + + +L+A
Sbjct: 219 AIRGERDIALGNIVGSNIFN--ILAILGITAVVTPIPVDARFLNVDTPVVIGITLLLLAL 276
Query: 186 VW-DGQIDWFEAMVLGILYILYFVV 209
V+ G+++ + + Y+ Y +
Sbjct: 277 VYFVGRMNRLVGGGMLVAYVAYIAL 301
Score = 45.6 bits (103), Expect = 0.002
Identities = 45/242 (18%), Positives = 100/242 (41%), Gaps = 25/242 (10%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
+ A + TS PE V++ + + + IG ++GS + N P+ +
Sbjct: 38 IVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIANILLVLGTAALIG--PLVL 95
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
V +D+L + L W G++ E + V+ ++ ++ I
Sbjct: 96 TFADVRKDLLWMTGAVLFLPYAFWSGEVSHVEGL-----------VLIGALAVYLFIS-- 142
Query: 224 WAACCKKNNGVTASLN-DNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFI 282
K + G ++ ++ + G+ G + + + + +I + F +
Sbjct: 143 ----LKGSRGEVDDIDAPTSLWIGGGLTILGL--VTVMVGAHYLVQSASIIARQ---FGV 193
Query: 283 PESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVS 342
E+++G++ +A G LPE + + + RGE I + N +G+N IL LG+ ++ +
Sbjct: 194 SEAMIGLSIVAIGTSLPELATTVMAAIRGERDIALGNIVGSNIFNILAILGITAVVTPIP 253
Query: 343 LE 344
++
Sbjct: 254 VD 255
Score = 33.9 bits (74), Expect = 8.1
Identities = 18/59 (30%), Positives = 27/59 (45%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F + ++G + FG PE + G+ GI + N +G+N IL LG LI
Sbjct: 32 FGVAPIIVGAVVVGFGTSTPELLVSLQAALGGQPGIAIGNVIGSNIANILLVLGTAALI 90
>UniRef50_Q0W2P1 Cluster: Putative Na(+)/Ca(2+) antiporter; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
Na(+)/Ca(2+) antiporter - Uncultured methanogenic
archaeon RC-I
Length = 308
Score = 46.4 bits (105), Expect = 0.001
Identities = 69/345 (20%), Positives = 139/345 (40%), Gaps = 47/345 (13%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L + G+ L + D+ + + IP +V T +++ TS PEF V + S
Sbjct: 3 MLLELIGLLVGIGLLVKGADWLVESARDLAFAAGIPASVIGLTLVAMGTSVPEFVVGIDS 62
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
+ +G ++G+ + N ++ R + R + + +++L
Sbjct: 63 ALSGVGQIAVGNVIGANISNLCLIIGVAAIVNRIHVS---RSIARVDMPFAFGVTLLFLL 119
Query: 186 V-WDGQIDWFEAMVL---GILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDN 241
+ DG I + ++ GILYI + ++ D T ++ N
Sbjct: 120 LSLDGTIGLIDGVIFIGAGILYIYNIYRRAGGERKVLVAD-------------TDTVK-N 165
Query: 242 NVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEA 301
V + GI + V G +T A+ N F + ++ +T +A G +PE
Sbjct: 166 LVLLAIGI--------ACVILGGKVTVDSAVSLANA--FQVSPFLIAVTIIAIGTSMPEM 215
Query: 302 CSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGID 361
+ + SR+ EG + + N +G+ + LF LG ++ L I G + +L+ GI
Sbjct: 216 VTALVASRKDEGDLVMGNCIGSVIVNTLFILGAAAIVS--PLPIAGVIDILILL---GI- 269
Query: 362 FXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFIVFAIL 406
+ + + + + GI+L +LYV+F+ + ++
Sbjct: 270 ----------IVLLLPILVTRSQIGHREGILLVVLYVIFVGYKVI 304
>UniRef50_A0RUT9 Cluster: Ca2 /Na antiporter; n=1; Cenarchaeum
symbiosum|Rep: Ca2 /Na antiporter - Cenarchaeum
symbiosum
Length = 294
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/238 (21%), Positives = 95/238 (39%), Gaps = 20/238 (8%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
V T ++ TS PE ++ ++ ++ +G ++GS + N IA+
Sbjct: 26 VIGMTVVAYGTSTPELAASLAASG-EHGELILGNVIGSNIANVGMIIGISAILVF--IAV 82
Query: 164 DMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKI 223
+ R+V I + +LV DG++ ++ +VL + + + F ++ +
Sbjct: 83 SRSTLRREVPIMIGASLLLVLLSIDGEVAGYDGIVLIGVLVAFTAYTFRGIR------ER 136
Query: 224 WAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIP 283
+G L + + G+ G V N + F +
Sbjct: 137 SGGSAPPADGGRFYLKSGGM-IAAGVALLGAGAWLAVENAVVLAR----------AFGLS 185
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
E V+G T +A G LPE + + +RG IGV N +G+N IL +G+ +I V
Sbjct: 186 EMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGVASMIAAV 243
Score = 39.5 bits (88), Expect = 0.16
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ + V T +++ TS PE +V++ +D+G+G I+GS ++N
Sbjct: 184 LSEMVIGTTVIAIGTSLPELVTSVVAIKRGHTDIGVGNIIGSNIYNILMIMGVASMIAAV 243
Query: 160 PIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFV 208
P+A + T ++ ++ VL A G W A ++ Y Y V
Sbjct: 244 PVAPGV--FTEYGIMICFSLVVLAAAKTGGIGRWIGAGLVA-AYAAYIV 289
>UniRef50_Q8T929 Cluster: Cation-exchanger protein 1; n=3;
Tetrahymena thermophila|Rep: Cation-exchanger protein 1
- Tetrahymena thermophila
Length = 594
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/149 (21%), Positives = 68/149 (45%), Gaps = 4/149 (2%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI- 124
LL ++ +Y F +L+ + Y P + + + K+ Q+VA T +++ P+ ++
Sbjct: 53 LLTILIPLYAFRMLSQISEYYLSPALAKVSKCFKLSQSVAGVTLLALGNGGPDVATAIVA 112
Query: 125 -STFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
S+ + +G+I G+ LF + I I + RD++ Y++ V+
Sbjct: 113 GSSGGDSITIAVGSIFGAGLFVTTYTLQNVIQNAGS-IHIKSKTFVRDMVFYLIGCCVVF 171
Query: 184 AFVWDGQIDWFEAMVLGILYILY-FVVMF 211
+ G I+ A+ +Y L+ F V++
Sbjct: 172 IYTIVGSINLGMAIGFMSIYGLFLFTVIY 200
>UniRef50_Q1JSU5 Cluster: Calcium antiporter, putative; n=3;
Apicomplexa|Rep: Calcium antiporter, putative -
Toxoplasma gondii
Length = 466
Score = 46.0 bits (104), Expect = 0.002
Identities = 29/143 (20%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
++ TLL V ++Y + + + + +P++ + + + E V + D
Sbjct: 327 LFIVTLLIAVHSEYLVGSIHDVVTNYGLPESFIGVILLPIVGNAAEHLTAVTVAMKNKVD 386
Query: 133 MGIGTIVGS----ALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWD 188
+ +G VGS ALF P+ + ++P+ + L+ ++ + V +A V D
Sbjct: 387 LAMGVAVGSSAQIALF-VFPFTVCAGWVLDQPLTLAVQPM--NALVLLMAVLVAMAIVQD 443
Query: 189 GQIDWFEAMVLGILYILYFVVMF 211
G+ +W E ++L Y++ +V +
Sbjct: 444 GESNWLEGVMLMAAYLMIAIVFW 466
>UniRef50_Q30YP0 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Desulfovibrio desulfuricans
G20|Rep: K+-dependent Na+/Ca+ exchanger related-protein
- Desulfovibrio desulfuricans (strain G20)
Length = 339
Score = 45.6 bits (103), Expect = 0.002
Identities = 50/279 (17%), Positives = 108/279 (38%), Gaps = 10/279 (3%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D + + + I + V T +++ TS PEF V+ + S + + +VGS +F
Sbjct: 21 DRLVEGASALARRVGISELVIGLTIVALGTSLPEFLVSFTAAVTGYSSISVANVVGSNIF 80
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDV-LIYMVNISVLVAFVWDGQIDWFEAMVLGILY 203
N P+ + + RD ++ +LV G + + VL + +
Sbjct: 81 NLGLILGGVAMLR--PVMPERDIMRRDAPILVCCTTFILVCASVTGSLPRWAGAVLTLTF 138
Query: 204 ILYFV-VMFNSMKAFVLIDKIWAACCKKNNGVTASL----NDNNVSVEEGIDNKGFNDPS 258
Y ++ S F ++ G T + + + + E + +
Sbjct: 139 AGYIAWLIIKSRMEFAAVNASLQTVLSSRTGSTLNSPVLPGEPDRTTAELPLWRALGGIA 198
Query: 259 PVTNGTTMTEKPAIDEKNGHTFF--IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIG 316
T+ + ++ + + E ++G+T +A G LPE + + S +G +
Sbjct: 199 AGLIALTLGSRLVVNGATAIAAWLGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMM 258
Query: 317 VSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLI 355
+ N +G++ LG+ L+R +S++ N A+ +
Sbjct: 259 LGNLIGSDLFNFAGVLGITALLRPLSVDASALPNLALSV 297
Score = 35.1 bits (77), Expect = 3.5
Identities = 22/102 (21%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L + + + T ++ TS PE V+++F ++M +G ++GS LFN
Sbjct: 222 LGVSEWLIGLTIVAGGTSLPELVTCVVASFKGRNEMMLGNLIGSDLFN--FAGVLGITAL 279
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL 199
P+++D + L + +L+ G++ E ++L
Sbjct: 280 LRPLSVDASALPNLALSVFTVLLILLLLRLRGRLGKAEGLLL 321
>UniRef50_A7HVG0 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Parvibaculum lavamentivorans DS-1|Rep: Na+/Ca+
antiporter, CaCA family - Parvibaculum lavamentivorans
DS-1
Length = 350
Score = 45.2 bits (102), Expect = 0.003
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 2/131 (1%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
++ +VC D+ + + + + A T ++ TS PE V++ + + +G
Sbjct: 13 VILLVCGDFLVRGATALAARYGVSPLLIALTIVAFGTSAPELLVSIRAALAGSPGIALGN 72
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
+VGS + N PIA R V ++++ M +L+ + G + +++ +
Sbjct: 73 VVGSNIANIFLILGLPALIY--PIACTGRTVPHNMIVMMAASVLLIVLCFVGTLSFWQGV 130
Query: 198 VLGILYILYFV 208
+L L Y V
Sbjct: 131 LLISLLTAYLV 141
Score = 39.5 bits (88), Expect = 0.16
Identities = 28/118 (23%), Positives = 48/118 (40%), Gaps = 1/118 (0%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I + + V + ++V TS PE +V++ F +DM +G I+GS + N
Sbjct: 225 IAQAFGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMVVGNIIGSNIMNILAILGVT 284
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMF 211
PI D V++ V + +L + G++ +V Y Y MF
Sbjct: 285 ALIAPLPIDPDFLRFHLWVMLAAV-VMLLPMTMTRGKVGRLTGVVFLCAYGAYLYAMF 341
Score = 38.3 bits (85), Expect = 0.38
Identities = 20/75 (26%), Positives = 37/75 (49%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
++ +T +AFG PE + G GI + N +G+N I LGLP LI ++
Sbjct: 39 LIALTIVAFGTSAPELLVSIRAALAGSPGIALGNVVGSNIANIFLILGLPALIYPIACTG 98
Query: 346 QGAENTAVLINSAGI 360
+ + +++ +A +
Sbjct: 99 RTVPHNMIVMMAASV 113
Score = 38.3 bits (85), Expect = 0.38
Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Query: 280 FFIPESVMGMTFLAFGGCLPE-ACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F + ++V+G++ +A G LPE A S+ + RR + V N +G+N + IL LG+ LI
Sbjct: 229 FGVSDAVIGLSLIAVGTSLPELATSVMAVFRRNNDMV-VGNIIGSNIMNILAILGVTALI 287
Query: 339 RTVSLE 344
+ ++
Sbjct: 288 APLPID 293
>UniRef50_A6Q9R1 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
n=1; Sulfurovum sp. NBC37-1|Rep: Calcium:H+/Na+
antiporter, CaCA family - Sulfurovum sp. (strain
NBC37-1)
Length = 310
Score = 45.2 bits (102), Expect = 0.003
Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 2/152 (1%)
Query: 71 FGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
F I+ + A++ + I E I IP+ + AT +++ TS PE ++ ++
Sbjct: 3 FVIFVIAMGALIWGAELIIKQSEKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNH 62
Query: 130 ESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDG 189
+ ++ I ++GS + N I+ +D +V + V + + DG
Sbjct: 63 KPEIAISNVIGSNILNITLVLASVFLIARN-ISPKRDFFAKDSTWALVPVLVFILMILDG 121
Query: 190 QIDWFEAMVLGILYILYFVVMFNSMKAFVLID 221
I F+A++L +L Y + + ++ L D
Sbjct: 122 VISRFDAVLLLLLMGAYLLFLLQDAQSIPLED 153
Score = 43.6 bits (98), Expect = 0.010
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK F IPE ++G T +A G LPE + S + I +SN +G+N L I L
Sbjct: 25 EKIALKFNIPEFIIGATLIALGTSLPEMAASIAASMNHKPEIAISNVIGSNILNITLVLA 84
Query: 334 LPWLI-RTVS 342
+LI R +S
Sbjct: 85 SVFLIARNIS 94
Score = 38.7 bits (86), Expect = 0.28
Identities = 23/84 (27%), Positives = 35/84 (41%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
+L IV + + I + I + V +S+ TS PE V++ + + DM IG
Sbjct: 176 ILVIVGAHFTVESASEIAKSFGISEWVIGIVMISLGTSMPELVVSISAAMKGKVDMAIGN 235
Query: 138 IVGSALFNXXXXXXXXXXXXXTPI 161
I+GS L N PI
Sbjct: 236 IIGSNLANTTVVLGSAALANPMPI 259
>UniRef50_UPI00015BD6AB Cluster: UPI00015BD6AB related cluster; n=1;
unknown|Rep: UPI00015BD6AB UniRef100 entry - unknown
Length = 319
Score = 44.8 bits (101), Expect = 0.004
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 8/83 (9%)
Query: 65 FLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI 124
F+L V+ I + L ++ N ++++ +L IP+ ++++ S+ T+ PEF V +I
Sbjct: 3 FILIAVYMILIYVLAEVIVN-----AIDVLSHELNIPEGISSSVIASLVTTLPEFLVPLI 57
Query: 125 STFLTESD---MGIGTIVGSALF 144
S D +GIG+I G +F
Sbjct: 58 SFLKGSVDTTHIGIGSIFGGPMF 80
>UniRef50_A5UZB1 Cluster: Sodium/calcium exchanger membrane region
precursor; n=2; Roseiflexus|Rep: Sodium/calcium
exchanger membrane region precursor - Roseiflexus sp.
RS-1
Length = 336
Score = 44.8 bits (101), Expect = 0.004
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 70 VFGIYTFTLLAIVCNDYFIP-CVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL 128
V+G++ + IV ++P E + E + Q F++++TS PE V++ + +
Sbjct: 183 VYGLFALNAVLIVGAALYLPGLAETLAETTGLGQTFFGTIFVALSTSLPEVVVSIAALRI 242
Query: 129 TESDMGIGTIVGSALFN 145
DM +G I GS LFN
Sbjct: 243 GAIDMAVGNIFGSNLFN 259
>UniRef50_Q74MB9 Cluster: NEQ486; n=1; Nanoarchaeum equitans|Rep:
NEQ486 - Nanoarchaeum equitans
Length = 308
Score = 44.8 bits (101), Expect = 0.004
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 3/128 (2%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D F+ E I + L I + +S++TS PE V +++ +S++ +G I+GS
Sbjct: 24 DKFLESGERISKSLGIDDRLLGLILVSISTSLPELAVAILAALDNKSEIVLGDIIGSNFA 83
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIY-MVNISVLVAFVWDGQIDWFEAMVLGILY 203
N +P+ I + +V I+ + ++ L+ + D +D +EA+ + I +
Sbjct: 84 N--LGLGLGIGLIISPLVIKKETLFNEVPIHGAITLATLLLILNDSVLDKYEALTILIFF 141
Query: 204 ILYFVVMF 211
L + ++
Sbjct: 142 ALMLLNIY 149
Score = 38.7 bits (86), Expect = 0.28
Identities = 24/134 (17%), Positives = 63/134 (47%), Gaps = 2/134 (1%)
Query: 79 LAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTI 138
L I+ I ++ ++L + + ++ +++ TS PE V++IS+ + ++ +G +
Sbjct: 175 LVIISAKILINSTIVLAKNLNLMPYLVSSLVIAIGTSLPEITVSIISSLKRKINIALGDV 234
Query: 139 VGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMV 198
+GS +FN PI ++ + L+ ++ + ++ ++ + ++
Sbjct: 235 LGSNIFN--MGVILPIATIINPIHANIIVINHLFLLLLLTTYLTLSAYVKRKLTKIDGLI 292
Query: 199 LGILYILYFVVMFN 212
L I YIL+ + +
Sbjct: 293 LLIGYILFLTLFIS 306
>UniRef50_Q5JI20 Cluster: Sodium/calcium antiporter; n=1;
Thermococcus kodakarensis KOD1|Rep: Sodium/calcium
antiporter - Pyrococcus kodakaraensis (Thermococcus
kodakaraensis)
Length = 311
Score = 44.8 bits (101), Expect = 0.004
Identities = 24/60 (40%), Positives = 32/60 (53%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ E V+G T +A G LPE + + R G I V N +GAN + L LGL LIR +
Sbjct: 198 VAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLASLIRPI 257
Score = 41.1 bits (92), Expect = 0.053
Identities = 27/122 (22%), Positives = 47/122 (38%), Gaps = 3/122 (2%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I E L + + V AT +++ TS PE + + +G I+G+ + N
Sbjct: 192 IAEALGVAEYVIGATIVAIGTSLPEMTNALYGAIRERGSISVGNIIGANIMNALVVLGLA 251
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
P + VL+ M + ++ G +D ILY Y V++F+
Sbjct: 252 SLIRPIPTGASTLTI---VLVLMAMLPMIAELKRSGGLDRRIGFYFLILYAAYLVLLFSG 308
Query: 214 MK 215
K
Sbjct: 309 AK 310
Score = 33.9 bits (74), Expect = 8.1
Identities = 21/74 (28%), Positives = 35/74 (47%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
++ + ++ LPE + + S GI + NALG+ I LGL +IR +
Sbjct: 41 IISLVVISLATTLPEITTSAMASITKAEGIALGNALGSIFANIALILGLASVIRPLKAGS 100
Query: 346 QGAENTAVLINSAG 359
EN+ V++ S G
Sbjct: 101 GAYENSLVMLASLG 114
>UniRef50_Q5QYT1 Cluster: Ca2+/Na+ antiporter; n=26; Bacteria|Rep:
Ca2+/Na+ antiporter - Idiomarina loihiensis
Length = 325
Score = 44.4 bits (100), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ + V+G+T +A G LPE S +R+ E + + N +G+N L +G+ I V
Sbjct: 204 VSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGNVIGSNMFNTLAVVGIAGAIEPV 263
Query: 342 SLE 344
SLE
Sbjct: 264 SLE 266
Score = 43.6 bits (98), Expect = 0.010
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 6/140 (4%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL IV + + I L + V T +++ TS PE + +T E D+ +G
Sbjct: 182 LLLIVSSRALVWGAVNIAVSLGVSDLVIGLTVVAIGTSLPELASAIAATRKNEHDLALGN 241
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF----VWDGQIDW 193
++GS +FN P++++ ++RD + V +L+ F G+I+
Sbjct: 242 VIGSNMFN--TLAVVGIAGAIEPVSLEPLVLSRDWVAMAVLTLLLMVFGIRKARQGRINR 299
Query: 194 FEAMVLGILYILYFVVMFNS 213
+ LY+LY + + +
Sbjct: 300 VHGFIFICLYLLYTLYLLKT 319
Score = 35.5 bits (78), Expect = 2.7
Identities = 16/59 (27%), Positives = 30/59 (50%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
V+GM + FG PE + S +G + + NA G+N I LG+ ++ ++++
Sbjct: 39 VIGMVIIGFGTSAPEMVVSALASMQGNPALALGNAYGSNITNIALVLGITAMLAPIAVK 97
>UniRef50_A6CBK9 Cluster: Sodium/calcium exchanger protein; n=1;
Planctomyces maris DSM 8797|Rep: Sodium/calcium
exchanger protein - Planctomyces maris DSM 8797
Length = 368
Score = 44.4 bits (100), Expect = 0.006
Identities = 65/298 (21%), Positives = 111/298 (37%), Gaps = 17/298 (5%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A +LY I L D F I +IP + AT +S++T+ PE V+V
Sbjct: 21 ASILYCSLLILLGMLSITKGGDLFTDSSVEIARLTRIPPVIIGATIVSMSTTFPELMVSV 80
Query: 124 ISTFLTESDMG-----------IGTIVGSALFNXXXXXXXXXXXXXTPIA-IDMRPVTRD 171
T + D+ IG I+GS P++ + +
Sbjct: 81 TGTLAGKGDLAVGNALGSCLCNIGLIIGSCALLKGYLSRKRKTESGIPVSRLTIVGPGFF 140
Query: 172 VLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKN 231
+L V + V F G + A + V++ + A++L A + +
Sbjct: 141 MLFSGVLVWVFSLFSTGGAVTQTGAPAEFAIARWQAVILLCVLAAYILFSLRVAMASRHD 200
Query: 232 NGVTASLN---DNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMG 288
G L +N ++ + F V G+ + A+ F + E ++G
Sbjct: 201 FGEEQELPPLIENQIAYFFKLALMFFCGACLVVLGSRLLVTNAVVV--ARYFEVSELLIG 258
Query: 289 MTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQ 346
+T LA G LPE + +G G +G N +GAN L I + + LI + ++ Q
Sbjct: 259 LTILAIGTSLPEYTISVLSIIKGHGALGTGNIIGANVLNINMVIAICALIHPLPIQRQ 316
Score = 38.7 bits (86), Expect = 0.28
Identities = 26/149 (17%), Positives = 62/149 (41%), Gaps = 3/149 (2%)
Query: 62 QGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFV 121
Q A+ + + L ++ + + ++ ++ + + T +++ TS PE+ +
Sbjct: 214 QIAYFFKLALMFFCGACLVVLGSRLLVTNAVVVARYFEVSELLIGLTILAIGTSLPEYTI 273
Query: 122 NVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISV 181
+V+S +G G I+G+ + N P+ I + V D + ++ I
Sbjct: 274 SVLSIIKGHGALGTGNIIGANVLNINMVIAICALIH--PLPIQRQTVILDGPVVILLIVA 331
Query: 182 LVAFVW-DGQIDWFEAMVLGILYILYFVV 209
++ W +I VL +Y+ Y ++
Sbjct: 332 MLGLAWRKKRISTASGAVLLAIYVGYLLL 360
>UniRef50_Q3E5U0 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=2; Chloroflexus|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Chloroflexus
aurantiacus J-10-fl
Length = 361
Score = 44.0 bits (99), Expect = 0.008
Identities = 21/59 (35%), Positives = 32/59 (54%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F + E ++G+T +A G LPE + I RGE I V N +G+N L +L L ++
Sbjct: 196 FGVSELIIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLVLSTTMIL 254
Score = 39.5 bits (88), Expect = 0.16
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
Query: 100 IPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT 159
+ + + T ++V TS PE +VI+ E D+ +G ++GS + N
Sbjct: 198 VSELIIGLTIVAVGTSLPEIATSVIAGLRGERDIAVGNVIGSNILNLLLVLSTTMILSPQ 257
Query: 160 PIAIDMRPVTRDVLIYMVNISVLV--AFVWDGQIDWFEAMVLGILYILY 206
PIA+ + D+ + M+ +++ F + E +L + Y+ Y
Sbjct: 258 PIAVPEATIWLDLPV-MLGAAIICWPIFFTRRMVSQREGSLLLVYYLSY 305
Score = 38.7 bits (86), Expect = 0.28
Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
+L ++ D + + L + + T ++V TS PE V++ + F + + +G
Sbjct: 11 VLLVLGADLLVRGAASLAAGLGVSSLIIGLTVVAVGTSSPEIAVSLQAAFDGQGAITLGN 70
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-AFVWDGQIDWFEA 196
IVGS + N P +D + RD+ I M+ S+L D + W +
Sbjct: 71 IVGSNIANVMLILGVAAMFGSLP--VDQQIFRRDLPI-MIGASLLTFLLALDRTLSWVDG 127
Query: 197 MVLGILYILYFVVMF 211
M++ + Y +M+
Sbjct: 128 MIMLLALTGYGWIMW 142
>UniRef50_A4XCI7 Cluster: Na+/Ca+ antiporter, CaCA family; n=2;
Salinispora|Rep: Na+/Ca+ antiporter, CaCA family -
Salinispora tropica CNB-440
Length = 352
Score = 44.0 bits (99), Expect = 0.008
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I DL +PQ V T ++V TS PE + + ESD+ +G + GS LFN
Sbjct: 235 IATDLGVPQLVIGMTLVAVGTSLPELVTTIQAQRQGESDLLVGNLFGSNLFNSLAGGAVI 294
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
T + P T L+ ++ ++ + A++
Sbjct: 295 AFAAPTTV-----PGTNIALVLVMGLTAVAAWM 322
Score = 37.9 bits (84), Expect = 0.50
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGAN 324
+P+ V+GMT +A G LPE + R+GE + V N G+N
Sbjct: 241 VPQLVIGMTLVAVGTSLPELVTTIQAQRQGESDLLVGNLFGSN 283
>UniRef50_Q8TM51 Cluster: Sodium/calcium exchanger protein; n=2;
Methanosarcina|Rep: Sodium/calcium exchanger protein -
Methanosarcina acetivorans
Length = 418
Score = 44.0 bits (99), Expect = 0.008
Identities = 28/138 (20%), Positives = 61/138 (44%), Gaps = 2/138 (1%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL + D F+ I E + + + T +S+ TS PE + ++ S + IG
Sbjct: 14 LLLVKGADLFVMSSSWIAERFGVSEFIIGLTLVSIGTSVPELASALTASLEHASGIVIGD 73
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
++GS + N + + + + RD I + ++ + + + D +I EA+
Sbjct: 74 VLGSNIAN--IGLIVSTAALLSNVRTEELMLRRDGYIMLFSLFIFLLSILDFRISRLEAL 131
Query: 198 VLGILYILYFVVMFNSMK 215
+ + Y +Y + + + +K
Sbjct: 132 IFLLFYFVYLLFLLDKVK 149
Score = 41.9 bits (94), Expect = 0.031
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 15/127 (11%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IPE+++G++ +A G LPE +R G I + N +G+N L LG L+ +
Sbjct: 305 IPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIGSNITNTLLILGCSGLVNPL 364
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK-FTLRRTVGIVLGILYVVF 400
++ I ++LFI + ++RT G++L +LY F
Sbjct: 365 TV--------------TKISIYYITPFMLFISLLLLLFIRTGWRIKRTEGVILLLLYCGF 410
Query: 401 IVFAILV 407
+ F L+
Sbjct: 411 MFFIFLL 417
Score = 33.9 bits (74), Expect = 8.1
Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 3/132 (2%)
Query: 81 IVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVG 140
+V YFI L+IP+ + + +++ TS PE V + + + + +G ++G
Sbjct: 286 VVGAKYFIEQSIFFALLLEIPETLIGISLVAIGTSLPELMVTISAARSGYASIALGNVIG 345
Query: 141 SALFNXXXXXX-XXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVL 199
S + N T I + +T +L + + + + W +I E ++L
Sbjct: 346 SNITNTLLILGCSGLVNPLTVTKISIYYITPFMLFISLLLLLFIRTGW--RIKRTEGVIL 403
Query: 200 GILYILYFVVMF 211
+LY + +F
Sbjct: 404 LLLYCGFMFFIF 415
>UniRef50_Q26FI1 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=9; Bacteroidetes|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Flavobacteria
bacterium BBFL7
Length = 317
Score = 43.6 bits (98), Expect = 0.010
Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 263 GTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALG 322
G+ + K A+D + IPES++ ++ +A G +PE + I + + E I + N +G
Sbjct: 181 GSELLVKGAVDI--AASLGIPESIIAVSMVALGTSVPELAASIIAALKKEKAISLGNLIG 238
Query: 323 ANSLAILFALGLPWLIRTVSLEIQG 347
+N I LG+ LI+ + ++ +G
Sbjct: 239 SNIFNIGSVLGITALIQPIQIQPEG 263
Score = 41.5 bits (93), Expect = 0.040
Identities = 26/125 (20%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I L IP+++ A + +++ TS PE ++I+ E + +G ++GS +FN
Sbjct: 192 IAASLGIPESIIAVSMVALGTSVPELAASIIAALKKEKAISLGNLIGSNIFNIGSVLGIT 251
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNIS---VLVAFVWD-GQIDWFEAMVLGILYILYFVV 209
I + + + + +M+ IS + +AF+ I ++ ++ Y+L+ +
Sbjct: 252 ALIQPIQIQPEGMGLLNNDIFWMLGISFALLPLAFLPKVYHISRYKGILFLAAYLLFIYL 311
Query: 210 MFNSM 214
F+++
Sbjct: 312 AFSTL 316
Score = 38.3 bits (85), Expect = 0.38
Identities = 31/153 (20%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L Y++ G+ +L ++ ++ + + L++ + + T +S ATS PE V++ S
Sbjct: 3 LFYLLIGL----VLLVIGGEFLVRSSVGLSLKLRLSRMIIGLTVVSFATSAPELIVSIQS 58
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
S + IG ++GS + N P+AID + + +M+ S+L+
Sbjct: 59 ALDGFSGLAIGNVIGSNIAN--IALVLGATALIAPLAID-KDFFKFNWPWMMAFSILLYI 115
Query: 186 VW---DGQIDWFEAMVLGILYILYFVVMFNSMK 215
+ + + W ++LG + + +++ + K
Sbjct: 116 LLLSDNNLVRWEGGILLGSIIVFLILLIRRARK 148
>UniRef50_A3PJ89 Cluster: Na+/Ca+ antiporter, CaCA family; n=3;
Rhodobacter sphaeroides|Rep: Na+/Ca+ antiporter, CaCA
family - Rhodobacter sphaeroides (strain ATCC 17029 /
ATH 2.4.9)
Length = 305
Score = 43.6 bits (98), Expect = 0.010
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+F I E+V+G+T +A G LPE + I + R I V N +G+N +L LG+ L+
Sbjct: 191 SFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFNVLGILGITGLV 250
Query: 339 RTVSLEIQGAE 349
L IQG +
Sbjct: 251 ----LPIQGLD 257
Score = 39.9 bits (89), Expect = 0.12
Identities = 23/66 (34%), Positives = 33/66 (50%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
++ I V+G+T + FG PE + G I V N LG+N IL LGL LI
Sbjct: 30 SYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIANILLILGLTALI 89
Query: 339 RTVSLE 344
V+++
Sbjct: 90 YPVAVD 95
Score = 39.5 bits (88), Expect = 0.16
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I I + V T ++V TS PE + I+ + S++ +G ++GS +FN
Sbjct: 188 IARSFGISEAVIGLTIVAVGTSLPELATSAIAAWRKHSEIAVGNVIGSNIFN--VLGILG 245
Query: 154 XXXXXTPI-AIDMRPVTRDV--LIYMVNISVLVAFVWDGQIDWFEAMVL 199
PI +D R + D+ ++ + VL+AF G W A++L
Sbjct: 246 ITGLVLPIQGLDPRFLREDMPWVLGCSLLLVLMAFALKGVPRWAGALLL 294
Score = 37.9 bits (84), Expect = 0.50
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 6/108 (5%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ +I V T + TS PE V++ + S + +G ++GS + N
Sbjct: 27 VARSYRISPMVIGLTIVGFGTSTPELLVSLNAALDGASSIAVGNVLGSNIANILLILGLT 86
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVL--VAFVWDGQIDWFEAMVL 199
P+A+D R V +D L +MV +VL + + DG + EA VL
Sbjct: 87 ALIY--PVAVDGRRVWKD-LAFMVGATVLLWIMLLGDG-LSRIEAGVL 130
>UniRef50_A5DQQ5 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 682
Score = 43.6 bits (98), Expect = 0.010
Identities = 26/147 (17%), Positives = 62/147 (42%), Gaps = 2/147 (1%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A L ++F I FTL+ + +D+ P + I + L++ +A TF+++ P+
Sbjct: 90 AILPIILFLILCFTLVGTIASDFLCPNLYTISKILRLSDRLAGLTFLALGNGAPDVLGTY 149
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
+ + + + +VG+A F P + D +++ V+
Sbjct: 150 KAMSMNTESLAVSELVGAAFF--ATTIVVGLIAVIHPFEVKRDSFIIDFGFFLLAAMVVF 207
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVM 210
+ + + ++ L ++Y+ Y +V+
Sbjct: 208 VAIVRSTLSIWTSLSLCLIYLSYVLVL 234
>UniRef50_Q50776 Cluster: ORF318; n=3; Methanothermobacter
thermautotrophicus|Rep: ORF318 - Methanobacterium
thermoformicicum
Length = 160
Score = 43.6 bits (98), Expect = 0.010
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
IP +MG+ LA G +PE + +G + + LG+N+ IL +G+P LI V
Sbjct: 45 IPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVPALIAPV 104
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
+E + F +++ G L+R+ GI+L +Y+ ++
Sbjct: 105 PVE------------PLSLRFDAPIMILVTVLLVLLIKQGDMKLKRSGGIILLAVYISYV 152
Query: 402 VFAILV 407
V + V
Sbjct: 153 VMRLFV 158
Score = 40.3 bits (90), Expect = 0.093
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 1/152 (0%)
Query: 58 EQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCP 117
E R+ L + + FT L I C VEL + IP + +++ TS P
Sbjct: 4 ETQREPLDLKKLALTVVGFTGLVIGCRILVYSGVEL-ADIAGIPAMIMGLFTLAIGTSIP 62
Query: 118 EFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV 177
E V + S ++ IGT++GS FN P+ ++I +
Sbjct: 63 ELVVTLSSAVKGLHELSIGTVLGSNTFNILVGIGVPALIAPVPVEPLSLRFDAPIMILVT 122
Query: 178 NISVLVAFVWDGQIDWFEAMVLGILYILYFVV 209
+ VL+ D ++ ++L +YI Y V+
Sbjct: 123 VLLVLLIKQGDMKLKRSGGIILLAVYISYVVM 154
>UniRef50_A4M7B3 Cluster: Na+/Ca+ antiporter, CaCA family; n=1;
Petrotoga mobilis SJ95|Rep: Na+/Ca+ antiporter, CaCA
family - Petrotoga mobilis SJ95
Length = 320
Score = 43.2 bits (97), Expect = 0.013
Identities = 51/249 (20%), Positives = 100/249 (40%), Gaps = 14/249 (5%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L + + A T ++ TS PE V IS+ + + +G+G ++GS + N
Sbjct: 32 LGVSELFAGLTVVAFGTSAPELVVT-ISSSIKGASVGLGNVLGSNVANIGLILGISFLI- 89
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQ--IDWFEAMVLGILYILYFVVMFNSMK 215
+P I V ++ ++ V+ A + +G + ++ M+L ++ ++ K
Sbjct: 90 -SPTKIQKSTVNIEMPFLLIISVVIFAMIMEGNSVLTRYDGMILITFLFIFMAYLYYMAK 148
Query: 216 AFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEK 275
+ K +N + + S + I + G I K
Sbjct: 149 NDQQVRKQLV----ENEEMKKV--EKEESWAKIITFSALGLAMLIIGGELTVSNAVIFAK 202
Query: 276 NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
+ I ES++G+T +A G LPE + + + + I + N +G+N+ I LG+
Sbjct: 203 S---IGISESLIGVTIVAVGTSLPELVTAIVAAIKHSDDIVMGNIVGSNTFNIAAILGIS 259
Query: 336 WLIRTVSLE 344
LI S +
Sbjct: 260 ALINGASAD 268
Score = 35.9 bits (79), Expect = 2.0
Identities = 16/67 (23%), Positives = 33/67 (49%)
Query: 79 LAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTI 138
+ I+ + + + + + I +++ T ++V TS PE +++ D+ +G I
Sbjct: 185 MLIIGGELTVSNAVIFAKSIGISESLIGVTIVAVGTSLPELVTAIVAAIKHSDDIVMGNI 244
Query: 139 VGSALFN 145
VGS FN
Sbjct: 245 VGSNTFN 251
>UniRef50_Q5LW08 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=9; Rhodobacterales|Rep: K+-dependent
Na+/Ca+ exchanger related-protein - Silicibacter
pomeroyi
Length = 309
Score = 42.7 bits (96), Expect = 0.017
Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ + L + T ++V TS PE +VI+ + +S++ +G IVGS +FN
Sbjct: 192 VAQGLGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIFNVLGILGAT 251
Query: 154 XXXXXTPIAIDMRPVTRDV-LIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY 206
P+A V L V SVL+ +W + ++L + Y Y
Sbjct: 252 AVIAPIPVASRFALFDLPVALAAAVTFSVLL--LWRAGVSRGAGVLLLLAYAAY 303
Score = 38.3 bits (85), Expect = 0.38
Identities = 54/255 (21%), Positives = 105/255 (41%), Gaps = 31/255 (12%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
+ + L +P + T + TS PE V+V + D+ +G I+GS + N
Sbjct: 27 LAQRLGLPPLLIGLTVVGFGTSTPELLVSVDAALRGVPDIALGNILGSNIANILLIGGIT 86
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
PI + RD+ + ++ L + GQ+ V+G++ +L S
Sbjct: 87 SLIW--PIRGKPVGLWRDLTVMILATLALTPILLGGQV----IRVVGLVLLL-------S 133
Query: 214 MKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNG-------TTM 266
+ A++ +W+ ++ G A D + + + + F P+ + G +
Sbjct: 134 LVAYL----VWSY--RQAGGPCAE--DTETDLPD-VPARPFVAPALIGAGLLGLMIGARL 184
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
A+ G + ++ +G+T +A G LPE + I + R + I V N +G+N
Sbjct: 185 LVDGAVSVAQG--LGVSDAFIGLTIVAVGTSLPELATSVIAAYRRQSEIAVGNIVGSNIF 242
Query: 327 AILFALGLPWLIRTV 341
+L LG +I +
Sbjct: 243 NVLGILGATAVIAPI 257
>UniRef50_A4BC83 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Reinekea sp. MED297|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Reinekea sp. MED297
Length = 321
Score = 42.7 bits (96), Expect = 0.017
Identities = 27/146 (18%), Positives = 60/146 (41%), Gaps = 2/146 (1%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
+L I + ++ D F+ + +L +P + T +S+ TS PE + +
Sbjct: 1 MLMFSLAILVGLIFLVLSADRFVAGAAALANNLGVPHLIIGVTIVSLGTSAPEIIAAIFA 60
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
++ +G +GS + N PI + R V + LI + + A
Sbjct: 61 ALEGRIELAMGNAIGSNVAN--IGLVLGITALVAPIPVSKRLVGNENLIMFASTLMAGAL 118
Query: 186 VWDGQIDWFEAMVLGILYILYFVVMF 211
+++ + + +VL +L + + V ++
Sbjct: 119 LFNLYLSAIDGLVLLLLMVAFLVWIY 144
Score = 41.1 bits (92), Expect = 0.053
Identities = 22/59 (37%), Positives = 31/59 (52%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
F I E+V+G T +A G LPE + + + I + N LG+N IL L +P LI
Sbjct: 200 FQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFNILAVLSVPGLI 258
Score = 40.3 bits (90), Expect = 0.093
Identities = 19/52 (36%), Positives = 29/52 (55%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
I + +I + V AT ++V TS PE +V S D+ IG ++GS +FN
Sbjct: 196 IADMFQISEAVIGATIIAVGTSLPELAASVASALKKHHDIAIGNVLGSNIFN 247
Score = 36.3 bits (80), Expect = 1.5
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR-- 339
+P ++G+T ++ G PE + + G + + NA+G+N I LG+ L+
Sbjct: 35 VPHLIIGVTIVSLGTSAPEIIAAIFAALEGRIELAMGNAIGSNVANIGLVLGITALVAPI 94
Query: 340 TVSLEIQGAEN 350
VS + G EN
Sbjct: 95 PVSKRLVGNEN 105
>UniRef50_A0CH97 Cluster: Chromosome undetermined scaffold_18, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_18,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 543
Score = 42.7 bits (96), Expect = 0.017
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 4/161 (2%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAA--ATFMSVAT 114
+ Q G + YV+ +Y F ++ + + + ++ L +N A S
Sbjct: 8 ERQQSPGEIIGYVIGVLYFFGMIYYIYRKHLLSLFQMFMNYLDDNENEEQYKAILYSCLN 67
Query: 115 SCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI--AIDMRPVTRDV 172
S + STF +ESD+ + TI+GS F T +D RD
Sbjct: 68 SIQFLILCFYSTFSSESDLAVSTIIGSDAFMIFFVFSYILYKYPTHSHGVLDTWITIRDA 127
Query: 173 LIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
Y++++ VL + ++ A++L ++Y + +FNS
Sbjct: 128 FFYILSLFVLFICILLDFLNIGTAVILLVVYFANIIFIFNS 168
>UniRef50_Q6FNR5 Cluster: Similar to tr|Q12424 Saccharomyces
cerevisiae YDL206w; n=1; Candida glabrata|Rep: Similar
to tr|Q12424 Saccharomyces cerevisiae YDL206w - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 748
Score = 42.7 bits (96), Expect = 0.017
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICED-LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
F +L I+ +DY IP + I D LKI V+ T +++ + P+ S E+ +
Sbjct: 46 FMMLGILTSDYLIPSLSFISRDILKISDRVSGMTLLALGNAIPDITTTYQSMKRNETSLA 105
Query: 135 IGTIVGSALF 144
+G ++G F
Sbjct: 106 LGELIGGVFF 115
Score = 37.1 bits (82), Expect = 0.87
Identities = 17/63 (26%), Positives = 30/63 (47%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
I + V GMT LA G +P+ + + +R E + + +G + LG+ ++ TV
Sbjct: 71 ISDRVSGMTLLALGNAIPDITTTYQSMKRNETSLALGELIGGVFFLLTVILGVVGIVSTV 130
Query: 342 SLE 344
E
Sbjct: 131 KFE 133
>UniRef50_Q6CR91 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 638
Score = 42.7 bits (96), Expect = 0.017
Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD--M 133
F LL I +D+ P V + + + V A+ ++ S P+ F N+IS +ES +
Sbjct: 40 FVLLGICASDHLCPNVAYLTKSGNTSKGVIASILLAWCNSSPDLFSNLISWLNSESPATL 99
Query: 134 GIGTIVGSA--LFNXXXXXXXXXXXXXTPIAIDMR-PVTRDVLIYMVNISVLVAFVWDGQ 190
+G ++GS + + I R + D+L ++ ++ ++ V
Sbjct: 100 SLGEVLGSCGIIICIIQGLLFYCMKEQLDLTIVQRNSLVTDLLFALLAMTCVLWIVVANS 159
Query: 191 IDWFEAMVLGILYILYFV 208
+ W+ + ++ +Y++Y V
Sbjct: 160 VTWYASFIMVAIYVMYVV 177
>UniRef50_A6G117 Cluster: K+-dependent Na+/Ca+ exchanger protein;
n=1; Plesiocystis pacifica SIR-1|Rep: K+-dependent
Na+/Ca+ exchanger protein - Plesiocystis pacifica SIR-1
Length = 325
Score = 42.3 bits (95), Expect = 0.023
Identities = 33/156 (21%), Positives = 63/156 (40%), Gaps = 3/156 (1%)
Query: 59 QLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPE 118
+LR L+ G+ L ++ + + L Q V T ++ TS PE
Sbjct: 170 ELRGAKAWLFSGLGLVLGMALLVLGGSVLVNGASALALGLGASQRVVGLTIVAAGTSLPE 229
Query: 119 FFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVN 178
+VI++ D+ + ++GS +FN P+A+D V+ D +
Sbjct: 230 LVTSVIASVRGRDDIALTNVLGSNIFN--VFGILGTTTLIAPVAVDPELVSVDSWWMIGF 287
Query: 179 ISVLVAFVWDG-QIDWFEAMVLGILYILYFVVMFNS 213
++L + G ++ E VL L++ Y ++ S
Sbjct: 288 AALLFPLMRSGYRVSRLEGGVLVALFVAYLTLLVRS 323
Score = 41.9 bits (94), Expect = 0.031
Identities = 22/61 (36%), Positives = 34/61 (55%)
Query: 284 ESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL 343
+ V+G+T +A G LPE + I S RG I ++N LG+N + LG LI V++
Sbjct: 213 QRVVGLTIVAAGTSLPELVTSVIASVRGRDDIALTNVLGSNIFNVFGILGTTTLIAPVAV 272
Query: 344 E 344
+
Sbjct: 273 D 273
Score = 36.7 bits (81), Expect = 1.1
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 5/114 (4%)
Query: 98 LKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXX 157
L++ V T ++ TS PE V+ + E D+ + ++GS +FN
Sbjct: 33 LRVSPAVIGLTIVAAGTSMPELVVSTKAALAGEPDIALANVIGSNIFN--IAAIVGVAAL 90
Query: 158 XTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFE-AMVLG--ILYILYFV 208
P+ + V + + + + L DG +D E +LG + +I Y V
Sbjct: 91 VAPLRVLGNSVRLEWPVMFLAVCQLHLLARDGSVDRLEGGFLLGAQVAFIAYLV 144
>UniRef50_Q6CT58 Cluster: Similar to sgd|S0002365 Saccharomyces
cerevisiae YDL206w; n=1; Kluyveromyces lactis|Rep:
Similar to sgd|S0002365 Saccharomyces cerevisiae YDL206w
- Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 684
Score = 42.3 bits (95), Expect = 0.023
Identities = 19/63 (30%), Positives = 32/63 (50%)
Query: 281 FIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRT 340
FI + + GMT LA G +P+ S + +RG + + +LGA + +G L+R
Sbjct: 68 FISDRISGMTLLALGNAIPDITSTYKAMKRGTTTLAIGESLGAIFFLLTVVIGSMLLVRN 127
Query: 341 VSL 343
+ L
Sbjct: 128 IKL 130
Score = 37.9 bits (84), Expect = 0.50
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
TF + E+++G+T A+G + + S +R G I + + G+ L LF +G+ ++
Sbjct: 548 TFNLSEAILGLTVFAWGNSIGDLVSNVTFTRIGVLEIALGSCFGSPLLYFLFGVGVDGML 607
Query: 339 RTVSLEIQGAENTAVLIN------SAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIV 392
V L+ + E TA+ + G+ F V+ + + L + VG +
Sbjct: 608 --VLLQREYPEGTAIWSRHIDFDVNRGLVFNCIGIVIAFGIFIFVVPLNNWKLDKRVGCL 665
Query: 393 LGILYVVFIVFAILVEL 409
L LY + + EL
Sbjct: 666 LLFLYGIITTINVYFEL 682
>UniRef50_UPI0000E479B5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 441
Score = 41.5 bits (93), Expect = 0.040
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 4/99 (4%)
Query: 286 VMGMTFLAFGGCLPEA-CSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
V +TF+A G LP+ S + N G+NS+ + LGLPWLI +
Sbjct: 302 VTAITFVALGTSLPDTFASKTAAVNEATADNSIGNVTGSNSVNVFLGLGLPWLIAAI--- 358
Query: 345 IQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKF 383
GA++ + + G+ F I+L I ++
Sbjct: 359 YWGAKDDTFAVPAGGLAFSVATYTICAIMCVILLMIRRY 397
>UniRef50_A0YPB5 Cluster: Sodium-calcium exchanger; n=2;
Oscillatoriales|Rep: Sodium-calcium exchanger - Lyngbya
sp. PCC 8106
Length = 315
Score = 41.5 bits (93), Expect = 0.040
Identities = 19/56 (33%), Positives = 31/56 (55%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWL 337
I + ++ ++ +A G LPE F SRRG+ + + N LG+N L +G+P L
Sbjct: 203 IGKELIAISAVALGTSLPELAVTFSASRRGDAEVAIGNVLGSNIFNSLIVMGVPGL 258
Score = 34.3 bits (75), Expect = 6.1
Identities = 22/135 (16%), Positives = 60/135 (44%), Gaps = 2/135 (1%)
Query: 73 IYTFTLLAIV-CNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES 131
++ +L+ ++ +D F I L + T +++ TS PE ++ + + +
Sbjct: 10 VFVVSLIVLIKFSDIFTETAGKIGVSLGFSPFIVGVTIVAIGTSLPELVSSIFAVYQGAT 69
Query: 132 DMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQI 191
++ ++GS + N +P+ I + D+ +++ + +L + DG
Sbjct: 70 EIVASNVIGSNVAN-IFLIIGVATLLSSPLKITYNLLDVDLPLFVGSAFLLYFTLSDGDF 128
Query: 192 DWFEAMVLGILYILY 206
+ EA++ + Y+++
Sbjct: 129 SFGEAILCILAYLIH 143
Score = 33.9 bits (74), Expect = 8.1
Identities = 31/152 (20%), Positives = 70/152 (46%), Gaps = 4/152 (2%)
Query: 62 QGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFV 121
+ ++L + + T + ++ I + I + L I + + A + +++ TS PE V
Sbjct: 165 RSSYLFKQIIVLLICTACMFLGANFTIQSIIKIADILGIGKELIAISAVALGTSLPELAV 224
Query: 122 NVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISV 181
++ ++++ IG ++GS +FN I D+ + RD L ++ ++
Sbjct: 225 TFSASRRGDAEVAIGNVLGSNIFNSLIVMGVPGLFEDL-IIPDI--IIRDGLPMLLASTL 281
Query: 182 LVAFV-WDGQIDWFEAMVLGILYILYFVVMFN 212
L FV D ++ +E + +LY + +F+
Sbjct: 282 LFFFVTQDKKVTKWEGWLFFVLYAWFIGNLFD 313
>UniRef50_O04034 Cluster: F7G19.17 protein; n=6; Magnoliophyta|Rep:
F7G19.17 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 546
Score = 41.5 bits (93), Expect = 0.040
Identities = 28/136 (20%), Positives = 53/136 (38%), Gaps = 1/136 (0%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGI 135
F +L +F + + L + ++AA T +++ P+ F +V + + G
Sbjct: 104 FYILIKTAQTHFSTVTTKLADRLNLSPSMAAVTLLALGNGAPDVFASVAALRGGQYRTGF 163
Query: 136 GTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFE 195
G I+ + F P +D RDVL Y++ L G+I ++
Sbjct: 164 GAILSAGTF-VSAFVVGFVAIYAAPFPVDAASFVRDVLFYLIAALFLFYVYLSGEIFVWQ 222
Query: 196 AMVLGILYILYFVVMF 211
A+ YI + +F
Sbjct: 223 AIGFVGFYIFFVGFVF 238
>UniRef50_A1Z8H3 Cluster: CG13223-PA; n=2; Sophophora|Rep:
CG13223-PA - Drosophila melanogaster (Fruit fly)
Length = 527
Score = 41.5 bits (93), Expect = 0.040
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 73 IYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLT 129
IY F ++ I +YF P + +I + L++ ++ A T +++A P+FF + S T
Sbjct: 57 IYVFWMMQITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQT 113
>UniRef50_Q5V3E8 Cluster: Na+/Ca2+-exchanging protein; n=1;
Haloarcula marismortui|Rep: Na+/Ca2+-exchanging protein
- Haloarcula marismortui (Halobacterium marismortui)
Length = 335
Score = 41.5 bits (93), Expect = 0.040
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 86 YFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFL-TESDMGIGTIVGSALF 144
YF E + + +P V A ++V +S PE VIST + E +G+G IVGSA+F
Sbjct: 24 YFERAAERLSKYYGLPVAVHGAIVVAVGSSFPEISSVVISTVIHDEFSLGVGAIVGSAIF 83
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
N + V +D Y+ ISVL+ F+
Sbjct: 84 N-LLVIPALAALSSEELRSTRDIVHKDAQFYI--ISVLILFI 122
>UniRef50_UPI0000E47BA9 Cluster: PREDICTED: similar to
sodium-calcium exchanger; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to sodium-calcium
exchanger - Strongylocentrotus purpuratus
Length = 766
Score = 41.1 bits (92), Expect = 0.053
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
Query: 282 IPESVMGMTFLAFGGCLPEACS---IFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
I SV G+T +A G +P+ + I + + IG N G+NS+ + LGLPW+I
Sbjct: 627 IEPSVAGITIIALGTSVPDTFASRTAAIQDQHADAAIG--NITGSNSVNVFLGLGLPWII 684
Query: 339 RTVSLEI 345
+ + L +
Sbjct: 685 KVMYLYV 691
Score = 33.9 bits (74), Expect = 8.1
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 7/51 (13%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF--LTE-----SDMGIGTIVGSALFN 145
+ VA T M++ +S PE +N + T LTE +G TI+GSA FN
Sbjct: 101 ETVANLTLMALGSSAPEILLNTVETLQNLTEPPNRKDSLGTFTIIGSAAFN 151
>UniRef50_Q9AVI2 Cluster: Putative senescence-associated protein;
n=1; Pisum sativum|Rep: Putative senescence-associated
protein - Pisum sativum (Garden pea)
Length = 284
Score = 41.1 bits (92), Expect = 0.053
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 68 YVVFGIYT---FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI 124
Y+V G++ F LL DYF P +E + E LK+P VA + + P+ F ++
Sbjct: 142 YLVLGVWLAALFYLLGNTAADYFCPSLEHLSELLKLPPTVAGVVLLPLGNGAPDVFASIA 201
Query: 125 STFLTES 131
S T++
Sbjct: 202 SFVGTDT 208
>UniRef50_Q5CSH9 Cluster: Calcium antiporter, Na/Ca exchange
associated membrane protein with 11 transmembrane
domains; n=2; Cryptosporidium|Rep: Calcium antiporter,
Na/Ca exchange associated membrane protein with 11
transmembrane domains - Cryptosporidium parvum Iowa II
Length = 473
Score = 41.1 bits (92), Expect = 0.053
Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Query: 77 TLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIG 136
T+L + ++ + + + + +N + + + E V ++D+ IG
Sbjct: 336 TILISIISECLVDSINGFISEWRFSENFIGVILLPLVGNAAEHITAVSVAIKNKTDLTIG 395
Query: 137 TIVGS----ALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
+GS ALF P+ + PV+ +L+ + N+ +++ V DG+ +
Sbjct: 396 VAIGSSTQIALF-VVPFSVIVGWLLGKPMTLSFTPVSAIILL-LTNL-IVIGIVQDGESN 452
Query: 193 WFEAMVLGILYILYFVV 209
WFE ++L I Y + VV
Sbjct: 453 WFEGILLIISYCIVAVV 469
>UniRef50_Q9HN44 Cluster: Na+/Ca2+-exchanging protein; n=4;
Halobacteriaceae|Rep: Na+/Ca2+-exchanging protein -
Halobacterium salinarium (Halobacterium halobium)
Length = 344
Score = 41.1 bits (92), Expect = 0.053
Identities = 24/107 (22%), Positives = 45/107 (42%)
Query: 77 TLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIG 136
TLL + + E + +P V + +++ +S PE +++ +G+G
Sbjct: 22 TLLIWAGSSWLEAAAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVG 81
Query: 137 TIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV 183
IVGSA+FN P+ V ++ YM+ +S L+
Sbjct: 82 AIVGSAIFNILVVPGLAGITTTQPLDATRTVVYKEAQFYMLAVSTLL 128
Score = 39.9 bits (89), Expect = 0.12
Identities = 22/60 (36%), Positives = 32/60 (53%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
TF IP + G+T LA LP+A +R G G + N LG+N+ +L A+ + LI
Sbjct: 218 TFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTSLGNVLGSNTFDLLVAIPIGVLI 277
Score = 36.7 bits (81), Expect = 1.1
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 271 AIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILF 330
A ++ + H + +P V G +A G PE S+ + + G G+GV +G+ IL
Sbjct: 35 AAEQLSAH-YGLPAVVQGSIVVAIGSSFPELLSVLVTALDGSFGLGVGAIVGSAIFNILV 93
Query: 331 ALGLPWLIRTVSLE 344
GL + T L+
Sbjct: 94 VPGLAGITTTQPLD 107
>UniRef50_UPI00004993FC Cluster: Na/Ca,K-exchanger; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: Na/Ca,K-exchanger - Entamoeba
histolytica HM-1:IMSS
Length = 575
Score = 40.7 bits (91), Expect = 0.071
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 5/139 (3%)
Query: 52 DGIFTDEQL--RQGAFLLYVVFGIYTFTLLAIVCNDYFIP-CVELICEDLKIPQNVAAAT 108
D + +D Q + G FL+Y++ +Y+ IV Y IP C +I +N A
Sbjct: 5 DFVLSDAQPFEQYGFFLVYIIGLLYSGYGFYIVVEYYLIPACNNCSKVVTRIIKNHFLAN 64
Query: 109 FMSVATSC-PEFFVNVIS-TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMR 166
+ + SC PEFFV +I L + I G L N + +
Sbjct: 65 LIMITASCMPEFFVGLIGYALLGDMIFPASIIFGCTLVNSVLLTGLGSFISLDNVVVTKT 124
Query: 167 PVTRDVLIYMVNISVLVAF 185
RD ++V++ ++ F
Sbjct: 125 AFVRDATFFIVSVIIIYFF 143
>UniRef50_A6Q338 Cluster: Calcium:H+/Na+ antiporter, CaCA family;
n=3; Epsilonproteobacteria|Rep: Calcium:H+/Na+
antiporter, CaCA family - Nitratiruptor sp. (strain
SB155-2)
Length = 308
Score = 40.7 bits (91), Expect = 0.071
Identities = 23/102 (22%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D+ + I L + + + ++ TS PE V++++ ++DM IG I+GS +
Sbjct: 183 DFAVESASHIARSLGVSEWLIGLFLIAFGTSLPELVVSIVAAMNDKADMSIGNIIGSNVA 242
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
N P+ ++M D+L ++ SV++ F+
Sbjct: 243 N--FSVVLGSAALVNPLHVNMHTYAFDILTAII-ASVMLIFI 281
Score = 40.3 bits (90), Expect = 0.093
Identities = 20/74 (27%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Query: 73 IYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES 131
I+ ++ A++ D+ I E I I + V AT +++ TS PE ++ +++ +S
Sbjct: 5 IFILSMAALIKGADFIIKESEKIALHFDISEFVIGATLVALGTSLPEMAASIAASYNHKS 64
Query: 132 DMGIGTIVGSALFN 145
D+ I ++GS + N
Sbjct: 65 DLAISNVIGSVIIN 78
Score = 37.5 bits (83), Expect = 0.66
Identities = 21/64 (32%), Positives = 32/64 (50%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK F I E V+G T +A G LPE + S + + +SN +G+ + I LG
Sbjct: 25 EKIALHFDISEFVIGATLVALGTSLPEMAASIAASYNHKSDLAISNVIGSVIINITLVLG 84
Query: 334 LPWL 337
+ +L
Sbjct: 85 IVFL 88
>UniRef50_A4FI39 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: K+-dependent Na+/Ca+ exchanger related-protein
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 342
Score = 40.7 bits (91), Expect = 0.071
Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 5/120 (4%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXX 153
I ED I V AT +++A + +FF+ V +GIG +VGS +F+
Sbjct: 216 ILEDFGIEGTVFGATIVTLALTIEDFFLTVEPVRKGVPAIGIGNVVGSLVFSVTGKLGII 275
Query: 154 XXXXXTPIAIDMRPVTRDVLIYMVNISVLVA-FVWDGQI-DWFEAMVLGILYILYFVVMF 211
+ I ++ T + + +V ++VL A F+ G++ W +LG LY +Y+VV F
Sbjct: 276 VLAGGS-IVVEPEVPTWHLPVLIV-LTVLAAYFLHTGRLRRWHGYTLLG-LYAVYWVVSF 332
>UniRef50_Q0IUM5 Cluster: Os11g0148000 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os11g0148000 protein -
Oryza sativa subsp. japonica (Rice)
Length = 293
Score = 40.7 bits (91), Expect = 0.071
Identities = 36/174 (20%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES--DM 133
F +LA +F P V + L++ ++AA T +++ P+ F + +
Sbjct: 78 FRVLAAAAGTHFSPAVSRLAARLRLSPSMAAVTLLALGNGAPDAFASAAALGGAGGMRRA 137
Query: 134 GIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDW 193
G+ I+ + F P A+ RDV Y++ S L +I
Sbjct: 138 GLAAILSAGAF-VSAFVVGAVALIAAPFAVPPASFARDVFFYLLAASGLFYIYLSAEIYL 196
Query: 194 FEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEE 247
++A+ L +L+ ++FV + M + + NG+ + D V+VE+
Sbjct: 197 WQAIGL-VLFYVFFVGLVVYMDLDAEGKAVSTTELEVVNGIGRVVMDLPVTVED 249
>UniRef50_A4RX12 Cluster: CaCA family transporter: sodium
ion/potassium ion/calcium ion; n=1; Ostreococcus
lucimarinus CCE9901|Rep: CaCA family transporter: sodium
ion/potassium ion/calcium ion - Ostreococcus lucimarinus
CCE9901
Length = 569
Score = 40.7 bits (91), Expect = 0.071
Identities = 28/133 (21%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Query: 79 LAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST---FLTESDMGI 135
LA+ +F+P +E +KI A T +++ P+ + V L + ++ I
Sbjct: 149 LAVAAGTFFVPALEYTATLMKISPEAAGVTLLALGNGAPDLYAQVSELSEGVLPDLNVVI 208
Query: 136 GTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMV-NISVLVAFVWDGQIDWF 194
G+ +GS F + I+ + + ++ V NI++L+A + G +
Sbjct: 209 GSTLGSGFFIATVVLGVVIRASPNAVVINKDALGASMGLFAVANIALLLAMCF-GTFKMW 267
Query: 195 EAMVLGILYILYF 207
M + Y YF
Sbjct: 268 YTMTFFVSYATYF 280
>UniRef50_A7RSI7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 837
Score = 40.7 bits (91), Expect = 0.071
Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 14/139 (10%)
Query: 285 SVMGMTFLAFGGCLPEACSIFIMSRRGEGG-IGVSNALGANSLAILFALGLPWLIRTVSL 343
SV G+T +A G LP+ + + + G + N G NS+ + LGLPW++ T
Sbjct: 698 SVTGITIIAIGTSLPDTMASRSAALQDTGADAAIGNITGYNSVNVFLGLGLPWVMSTC-- 755
Query: 344 EIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKF---------TLRR-TVGIVL 393
A T ++S + F +L + ++ TL + G++L
Sbjct: 756 -YHAARGTVYKVSSGNLAFSVLVFALCGGVCLFLLVLRRYLYKGELGGPTLSKWMTGLLL 814
Query: 394 GILYVVFIVFAILVELGII 412
L+ +++V + L+ G I
Sbjct: 815 LFLWFIYVVLSSLMAYGHI 833
>UniRef50_Q9HS69 Cluster: Cation antiporter; n=2;
Halobacteriaceae|Rep: Cation antiporter - Halobacterium
salinarium (Halobacterium halobium)
Length = 318
Score = 40.7 bits (91), Expect = 0.071
Identities = 49/257 (19%), Positives = 94/257 (36%), Gaps = 14/257 (5%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGT 137
LL V + + + I T ++ AT+ PE FV+ + + +G
Sbjct: 17 LLLYVGAELLVSAASALALSHGIKAATVGVTVVAFATTAPELFVSTVGGITAGDSIALGN 76
Query: 138 IVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAM 197
IVGS + N P+ +D + + LV DG + + +
Sbjct: 77 IVGSNIANIGLVLGTAALLR--PMDVDKTLLYHHGPFMLAAALALVGLSLDGTLGALDGV 134
Query: 198 VLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDP 257
L L ++ ++ + D ++ TA+ D V V + G
Sbjct: 135 ALLALLAVFTAYIYRHAQQDD-DDVSLPDDVDMDDDATATARDYVVLVGAILLLLG-GSR 192
Query: 258 SPVTNGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGV 317
+ +T G + + F + +G+T +AFG +PE + + + R E +
Sbjct: 193 ALITGGRGVLME----------FGFSDLFIGLTVIAFGTSVPELATSVVSALRDEADFSI 242
Query: 318 SNALGANSLAILFALGL 334
N +G+N +L +G+
Sbjct: 243 GNVVGSNIYNVLAVIGI 259
>UniRef50_A6GKL8 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 320
Score = 40.3 bits (90), Expect = 0.093
Identities = 19/57 (33%), Positives = 30/57 (52%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
T + + V+G+T +A G LPE + + RGE + + N LG+N +L L P
Sbjct: 196 TLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFNLLAVLPFP 252
Score = 37.5 bits (83), Expect = 0.66
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSL-- 343
++GM + G PE + + G GGI + NA+G+N I LG+ LI+ + L
Sbjct: 41 LVGMLIVGLGTSAPEMLVSAMAALDGSGGIALGNAVGSNITNIGLVLGVSALIKPIRLHR 100
Query: 344 EIQGAENTAVLINSAGI 360
++ E VL+ + G+
Sbjct: 101 DVVRREIPVVLLITFGV 117
Score = 36.3 bits (80), Expect = 1.5
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
I L + V T +++ TS PE +V S E M IG ++GS +FN
Sbjct: 193 IASTLGVSDLVIGLTVVAIGTSLPELAASVASALRGEDAMAIGNVLGSNVFN 244
>UniRef50_Q6BSX2 Cluster: Similar to CA1231|IPF11817 Candida
albicans IPF11817 unknown function; n=1; Debaryomyces
hansenii|Rep: Similar to CA1231|IPF11817 Candida
albicans IPF11817 unknown function - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 710
Score = 40.3 bits (90), Expect = 0.093
Identities = 25/135 (18%), Positives = 57/135 (42%), Gaps = 2/135 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGI 135
F L + +DY P + I + L++ N+A T ++ P+ + L + I
Sbjct: 94 FIALGMTASDYLCPNLYTISKFLELSDNLAGLTLLAFGNGSPDVLSTYKAMSLDSGSLAI 153
Query: 136 GTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFE 195
++G+ALF P + RD ++ I++++ + + +
Sbjct: 154 SELMGAALF--IITVIVGSMAVVHPFKVPRDLFIRDAGFFLGVIALVLISLLNSYLSMVN 211
Query: 196 AMVLGILYILYFVVM 210
++L +Y++Y V++
Sbjct: 212 CILLIGVYVIYVVIV 226
>UniRef50_A3GGW1 Cluster: Sodium/calcium exchanger protein; n=2;
Pichia stipitis|Rep: Sodium/calcium exchanger protein -
Pichia stipitis (Yeast)
Length = 686
Score = 40.3 bits (90), Expect = 0.093
Identities = 25/131 (19%), Positives = 55/131 (41%), Gaps = 2/131 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGI 135
F L + +DY P + I + LK+ N++ T +++ P+ + + I
Sbjct: 62 FISLGLTASDYLCPNLYTISKFLKLSDNLSGLTLLALGNGSPDVLSTFKAMSFGSGSLAI 121
Query: 136 GTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFE 195
++G++LF P+ + R RD + Y++ +L+ + +
Sbjct: 122 SELMGASLF--VTTVVIGCIAIVHPLKVPRRLFVRDTIFYLMIACLLIFTLVRQSLTLPI 179
Query: 196 AMVLGILYILY 206
+++L Y+LY
Sbjct: 180 SIILVSSYVLY 190
>UniRef50_Q3A9V0 Cluster: Sodium/calcium antiporter; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep:
Sodium/calcium antiporter - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 334
Score = 39.9 bits (89), Expect = 0.12
Identities = 32/161 (19%), Positives = 67/161 (41%), Gaps = 8/161 (4%)
Query: 54 IFTDEQL--RQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMS 111
IFT ++ R A LL ++ + L+ +V YF+ + + + I +
Sbjct: 176 IFTPQRTIPRIRAILLQLIISL----LMIVVGAKYFVANLTQLAHLIGISPMALSLVITP 231
Query: 112 VATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRD 171
+AT PE F +V+ + + +G I G+ +F ++ D+ V
Sbjct: 232 IATELPEKFNSVVWMRSGKDTLALGNITGAMVFQSSVITSIGIIFTSWRLSTDV--VLSG 289
Query: 172 VLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFN 212
+L + ++ L + ++ + + G +YI Y + +FN
Sbjct: 290 ILAFFAAVAALFLVNFRRRLSAWTLIFNGCIYIFYLIYIFN 330
>UniRef50_Q1GMH1 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=1; Silicibacter sp. TM1040|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Silicibacter sp. (strain TM1040)
Length = 327
Score = 39.9 bits (89), Expect = 0.12
Identities = 61/266 (22%), Positives = 103/266 (38%), Gaps = 20/266 (7%)
Query: 104 VAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAI 163
V T + TS PE +V + + G +VGS + N PI +
Sbjct: 39 VIGLTLVGFGTSTPELVTSVQAGLSGAPGIAYGNVVGSNIANILLIAGISALL--CPIIV 96
Query: 164 DMRPVTRDVLIYMVNISVL--VAFVWD-GQIDWFEAMVLGILYILYFVVMFNSMKAFV-- 218
+ RD ++ ++ V +A VW G++ A+++ ++ + FVV A
Sbjct: 97 ARAALRRDAVVMLLAALVFSGLAAVWPMGRLSG-AALIIAMIGYITFVVRQERQNADTGA 155
Query: 219 LIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNK---GFNDPSPVTNGTTMTEKPAIDEK 275
L DK A G L+ G+ V G A+
Sbjct: 156 LHDKGEALA-----GAAPGLDPAQTKSGRGLAVSLLLALGGLVLVVVGGAALVNGAV--A 208
Query: 276 NGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
+F I E+V+G+T +A G +PE + I + + +G + N +G+N IL G
Sbjct: 209 LARSFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYNILGIGGTT 268
Query: 336 WLIRTVSL--EIQGAENTAVLINSAG 359
LI L +I + +++ SAG
Sbjct: 269 ALIAPSDLPGDILRFDAPVMILVSAG 294
Score = 39.5 bits (88), Expect = 0.16
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 94 ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
+ +I + V T ++V TS PE +VI+ + D+ G +VGS ++N
Sbjct: 209 LARSFEISETVIGLTIVAVGTSMPELVTSVIAALKRQGDVAFGNVVGSNIYN 260
Score = 34.7 bits (76), Expect = 4.6
Identities = 21/77 (27%), Positives = 34/77 (44%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
V+G+T + FG PE + G GI N +G+N IL G+ L+ + +
Sbjct: 39 VIGLTLVGFGTSTPELVTSVQAGLSGAPGIAYGNVVGSNIANILLIAGISALLCPIIVAR 98
Query: 346 QGAENTAVLINSAGIDF 362
AV++ A + F
Sbjct: 99 AALRRDAVVMLLAALVF 115
>UniRef50_A7ELS1 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 386
Score = 39.9 bits (89), Expect = 0.12
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
Query: 285 SVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
+V+G T L+ LPE + +R +GGI V+N +G+N+ + G+ +L
Sbjct: 276 NVLGTTILSIATTLPEKLVAILSGKRRQGGIIVANTVGSNTFLLTLCAGILFL------- 328
Query: 345 IQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFIV 402
A + L S GI F VLF+G RR +G L LY+ F+V
Sbjct: 329 ---AGDLEALKESVGI-FEVACMWGSSVILCGVLFVGG---RRWMGWGLAGLYLAFLV 379
>UniRef50_Q0AZ73 Cluster: Sodium/calcium exchanger membrane region;
n=1; Syntrophomonas wolfei subsp. wolfei str.
Goettingen|Rep: Sodium/calcium exchanger membrane region
- Syntrophomonas wolfei subsp. wolfei (strain
Goettingen)
Length = 336
Score = 39.5 bits (88), Expect = 0.16
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 67 LYVVFGIYTFTLLAIVCN-DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
L +V G F LL I+ D F+ V+ + ++P V A +AT PE F +VI
Sbjct: 188 LSLVIGQVLFALLLIIIGADMFVGAVKEVAVMYQVPAFVLALIITPIATELPEKFNSVIW 247
Query: 126 TFLTESDMGIGTIVGSALF 144
+ + +G I G+ +F
Sbjct: 248 ISREKDSLALGNITGAMVF 266
>UniRef50_Q9VDG5 Cluster: CG5685-PA, isoform A; n=5; Diptera|Rep:
CG5685-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 950
Score = 39.5 bits (88), Expect = 0.16
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIG-VSNALGANSLAILFALGLPWLIRT 340
I +SV + F+A G +P+ + I ++ EG + N G+N++ + +GL W I
Sbjct: 808 IKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAA 867
Query: 341 V 341
V
Sbjct: 868 V 868
Score = 38.3 bits (85), Expect = 0.38
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTE---SDMGIGTIVGSALFN 145
+ VA T M++ +S PE ++VI + + D+G GTIVGSA +N
Sbjct: 178 ETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYN 224
>UniRef50_Q5CI48 Cluster: Cation exchanger; n=2;
Cryptosporidium|Rep: Cation exchanger - Cryptosporidium
hominis
Length = 940
Score = 39.5 bits (88), Expect = 0.16
Identities = 21/82 (25%), Positives = 38/82 (46%)
Query: 262 NGTTMTEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNAL 321
NG + E + G T I +++G+T +A G + + + +SR G +G++
Sbjct: 796 NGVLVNELVECIKVIGLTLGIKPAILGLTIVAMGNSIADLFANVAVSRAGHAHMGLAGCY 855
Query: 322 GANSLAILFALGLPWLIRTVSL 343
GA +LF G +R + L
Sbjct: 856 GACVFLLLFGFGSSVFVRAIQL 877
>UniRef50_Q29QD0 Cluster: AT15857p; n=2; Drosophila
melanogaster|Rep: AT15857p - Drosophila melanogaster
(Fruit fly)
Length = 643
Score = 39.5 bits (88), Expect = 0.16
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 8/155 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE + E GH + + MG T A G L + M+ G + ++A+G
Sbjct: 486 TEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFF 545
Query: 327 AILFALGLPWLIRTV-SLEIQGAENTAVLINSAGID-FXXXXXXXXXXXXWIVLFIGKFT 384
++ + ++ + L + A T + G++ F W +G F
Sbjct: 546 TVVMSASTVMHVKNLFGLPVSEANQTG----NYGLNAFIFLNLGLFSTLLWSTT-LGFFA 600
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGIIFDRNVEL 419
RR+VGI + Y ++++FAIL+ +I +V+L
Sbjct: 601 -RRSVGIFSIVFYCIYLLFAILIHRKVIHSFSVDL 634
>UniRef50_Q21FU9 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=3; Gammaproteobacteria|Rep:
K+-dependent Na+/Ca+ exchanger related-protein -
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
17024)
Length = 331
Score = 39.1 bits (87), Expect = 0.22
Identities = 20/66 (30%), Positives = 33/66 (50%)
Query: 279 TFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLI 338
+F + V+G+T ++FG PE S + G + + NALG+N I LG LI
Sbjct: 39 SFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIANIGLVLGATLLI 98
Query: 339 RTVSLE 344
+ ++
Sbjct: 99 AAIPVQ 104
Score = 37.9 bits (84), Expect = 0.50
Identities = 17/65 (26%), Positives = 34/65 (52%)
Query: 280 FFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIR 339
F + ++G+T +A G LPE + + + +G I + N +G+N +L + +P +I
Sbjct: 207 FSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHDIALGNIIGSNIFNLLAVMAVPGIIS 266
Query: 340 TVSLE 344
+E
Sbjct: 267 PPIME 271
Score = 35.9 bits (79), Expect = 2.0
Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Query: 74 YTFTLLAI-VCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESD 132
+ L+A+ + ++ + + E + + T ++V TS PE +V+S D
Sbjct: 182 FAIGLIALMISSEILVWGAKTTAEYFSVSPLIIGLTVIAVGTSLPELAASVMSALKGHHD 241
Query: 133 MGIGTIVGSALFN 145
+ +G I+GS +FN
Sbjct: 242 IALGNIIGSNIFN 254
Score = 35.5 bits (78), Expect = 2.7
Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 85 DYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALF 144
D F+ I + + V T +S TS PE V++ ++ D+ IG +GS +
Sbjct: 27 DRFVAGSAAIAKSFGVAPLVIGLTIVSFGTSAPEVMVSISASLKDAGDLAIGNALGSNIA 86
Query: 145 NXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLV-AFVWDGQID-WFEAMVLGIL 202
N P+ + + R L ++ ++++ A ++ G + W ++L +L
Sbjct: 87 NIGLVLGATLLIAAIPV---QKHIFRHELPVLLLVTIISGALLYGGVLSPWEGWLLLALL 143
Query: 203 YIL 205
+L
Sbjct: 144 PVL 146
>UniRef50_A4A287 Cluster: Cation antiporter; n=1; Blastopirellula
marina DSM 3645|Rep: Cation antiporter - Blastopirellula
marina DSM 3645
Length = 382
Score = 39.1 bits (87), Expect = 0.22
Identities = 21/89 (23%), Positives = 39/89 (43%)
Query: 57 DEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSC 116
+E + + L V T++ V Y + + + +TF+++ TS
Sbjct: 156 EEAIEEKMSLTRAVITYLVATVVIFVAARYLSIVADRVAVVTGLGGTFVGSTFLALTTSL 215
Query: 117 PEFFVNVISTFLTESDMGIGTIVGSALFN 145
PE +++ + +DM IG I+GS FN
Sbjct: 216 PELVTTIVAVRMGAADMAIGNILGSNAFN 244
Score = 36.7 bits (81), Expect = 1.1
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 92 ELICEDLKIPQNVAAATFMSVATSCPEFFVNV----ISTFLTESDMGIGTIVGSALFN 145
++I E + ++A ++ ATS PEF +NV + + D+ +G I+GS+LFN
Sbjct: 6 DVIGEKSGLGSSLAGLVLLAAATSLPEFAINVNAVQLPDYTNGVDLAMGNILGSSLFN 63
>UniRef50_A0VWQ8 Cluster: Na+/Ca+ antiporter, CaCA family; n=5;
Alphaproteobacteria|Rep: Na+/Ca+ antiporter, CaCA family
- Dinoroseobacter shibae DFL 12
Length = 321
Score = 39.1 bits (87), Expect = 0.22
Identities = 62/324 (19%), Positives = 126/324 (38%), Gaps = 27/324 (8%)
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
G LL V G+ +L V + + I E I + + + TS PE V+
Sbjct: 2 GYDLLLVAVGL----VLLFVGGEGLVRGAVAIAERFGISKLLIGLVIVGFGTSTPELLVS 57
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
V + ++ +G +VGS + N TP+ R R+ + + L
Sbjct: 58 VNAALDGAPEIALGNVVGSNIANILLIIGIAAAI--TPVTGWDRGALREAFV-----ATL 110
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNN 242
VA G + ++ L+ VM + A+ L+ W ++ N + +
Sbjct: 111 VALATLGLVQ------ADVISRLHGTVMLAVLAAY-LVSTYWL---ERRNRQSQTFAHEA 160
Query: 243 VSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNG-----HTFFIPESVMGMTFLAFGGC 297
+ E+ + + P V G A G + + ++V+G++ +A G
Sbjct: 161 EAFEDIPITRPWQAPLFVVAGIAALVFGADLLVQGSVSIARAYGVSDAVIGLSLVAIGTS 220
Query: 298 LPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAE-NTAVLIN 356
LPE + + + + + + + N +G+N IL LG+ +I+ + + + E +T +++
Sbjct: 221 LPELATAVVAAIKRQSDVVLGNVIGSNIFNILAILGITVVIQPMDVAARFREIDTPIMVA 280
Query: 357 SAGIDFXXXXXXXXXXXXWIVLFI 380
++ + W VL +
Sbjct: 281 ASLLLLGLLFATRSIGRTWGVLML 304
Score = 35.9 bits (79), Expect = 2.0
Identities = 29/147 (19%), Positives = 58/147 (39%), Gaps = 5/147 (3%)
Query: 67 LYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIST 126
L+VV GI A D + I + V + +++ TS PE V++
Sbjct: 176 LFVVAGIAALVFGA----DLLVQGSVSIARAYGVSDAVIGLSLVAIGTSLPELATAVVAA 231
Query: 127 FLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFV 186
+SD+ +G ++GS +FN +A R + +++ ++ +L
Sbjct: 232 IKRQSDVVLGNVIGSNIFNILAILGITVVIQPMDVAARFREIDTPIMV-AASLLLLGLLF 290
Query: 187 WDGQIDWFEAMVLGILYILYFVVMFNS 213
I +++ Y Y V +F++
Sbjct: 291 ATRSIGRTWGVLMLTAYAAYMVFLFST 317
>UniRef50_Q6JAE1 Cluster: Putative K-exchanger-like protein; n=1;
Zea mays|Rep: Putative K-exchanger-like protein - Zea
mays (Maize)
Length = 516
Score = 39.1 bits (87), Expect = 0.22
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGI 135
F LL ++YF +E + L++P VA T +S+ P+ F +V+S F + D G
Sbjct: 123 FYLLGDTASEYFCASLEGLSAALRLPPAVAGVTLLSLGNGAPDVFASVVS-FASGDDGGG 181
Query: 136 GTIV 139
G V
Sbjct: 182 GVTV 185
>UniRef50_Q1NJT8 Cluster: K+-dependent Na+/Ca+ exchanger
related-protein; n=2; delta proteobacterium MLMS-1|Rep:
K+-dependent Na+/Ca+ exchanger related-protein - delta
proteobacterium MLMS-1
Length = 351
Score = 38.7 bits (86), Expect = 0.28
Identities = 19/53 (35%), Positives = 29/53 (54%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I E V+G+T A G LPE + F R+ + + V N +G+N +L LG+
Sbjct: 241 ISELVIGLTLAAIGTSLPELATCFAAIRQRQDTLLVGNIIGSNIFNLLMVLGI 293
Score = 36.3 bits (80), Expect = 1.5
Identities = 23/73 (31%), Positives = 36/73 (49%)
Query: 286 VMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEI 345
++G+T +AFG LPE S RG GI + N +G+N I L + L + L +
Sbjct: 79 LIGLTVVAFGTSLPELFIALGASWRGVPGIMLGNVIGSNIANIGLILAISLLFFPLRLAL 138
Query: 346 QGAENTAVLINSA 358
+ VL++ A
Sbjct: 139 RSVALEMVLLHLA 151
>UniRef50_A1Z7I2 Cluster: CG14743-PA; n=1; Drosophila
melanogaster|Rep: CG14743-PA - Drosophila melanogaster
(Fruit fly)
Length = 582
Score = 38.7 bits (86), Expect = 0.28
Identities = 30/145 (20%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G F + S M +TF + + + +++ G G + +G + ++ +G+
Sbjct: 439 GVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIE- 497
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ L +G VL G+ W L F RR+ G+ + L
Sbjct: 498 LVLQKKLNSRGQ---VVLYGDDGVTIYIFLVITITTTLWWCLTFN-FVARRSAGLFMWSL 553
Query: 397 YVVFIVFAILVELGII--FDRNVEL 419
+V+F+V+ +EL + F N+++
Sbjct: 554 FVLFLVYTTAIELQWVHGFQDNIQI 578
Score = 37.9 bits (84), Expect = 0.50
Identities = 30/145 (20%), Positives = 62/145 (42%), Gaps = 5/145 (3%)
Query: 66 LLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
LL+ + + +L N YF P +++ ++I + +A + VA S P+ VN +S
Sbjct: 48 LLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVN-LS 106
Query: 126 TFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAF 185
E G+ + A P ++ + RD+L ++ I ++ F
Sbjct: 107 PVRME---GLTFNIAMANALTIICLSGGAVCFIRPFRMNGHSIFRDLLFLLLIIELVRFF 163
Query: 186 VWDGQI-DWFEAMVLGILYILYFVV 209
+ D + W + +L +Y +Y ++
Sbjct: 164 MNDTALAPWIKGAILLSIYPIYLLI 188
>UniRef50_Q12424 Cluster: Putative cation exchanger YDL206W
precursor; n=2; Saccharomyces cerevisiae|Rep: Putative
cation exchanger YDL206W precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 762
Score = 38.7 bits (86), Expect = 0.28
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 270 PAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAIL 329
P++ + + F I + V GMT LA G LP+ S + + G + + G +
Sbjct: 58 PSLSYISSNIFHISDRVSGMTLLALGNALPDITSTYQSMKSGVTSLAIGELFGGIFFLLT 117
Query: 330 FALGLPWLIRTVSLE 344
+GL + T+ +
Sbjct: 118 VVIGLMGCVATIQFQ 132
>UniRef50_Q391I5 Cluster: Sodium/calcium exchanger membrane region;
n=14; Betaproteobacteria|Rep: Sodium/calcium exchanger
membrane region - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 336
Score = 38.3 bits (85), Expect = 0.38
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 18/158 (11%)
Query: 78 LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI------STFLTES 131
++ +V + F +E + E LKI + V + F +V T+ PE V ++ +
Sbjct: 13 IVILVAAEVFTNALEHLGERLKISEGVTGSLFAAVGTALPETMVPLLALAGGTANQAVNE 72
Query: 132 DMGIGTIVGSALFNXXXXXXXXXXXXXT------PIAIDMRPVTRDVLIYMVNISVLVAF 185
++G+G I+G+ L IA + RD+ ++ S+ A
Sbjct: 73 EIGVGAILGAPLMLATLTTFLMTLAVIRSRGLRGTIAPERTGFVRDMNYFLAAFSLATAA 132
Query: 186 VWDGQIDW-----FEAMVLGILYILYFVVMFNSMKAFV 218
++ +W AM++GI Y++Y V+ F + V
Sbjct: 133 MFVPHHNWAVRALLAAMLVGI-YVMYVVMTFRASNQLV 169
>UniRef50_A5E210 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 250
Score = 38.3 bits (85), Expect = 0.38
Identities = 29/145 (20%), Positives = 60/145 (41%), Gaps = 5/145 (3%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICE-DLKIPQNVAAATFMSVATSCPEFFVN 122
A L + + F L +Y P + I + LK+P N+A T ++ P+ F
Sbjct: 104 AILPIICILLVLFISLGYTALEYLCPNLHTIAKAHLKMPDNLAGLTILAFGNGAPDIFGT 163
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYM-VNISV 181
+ ++ I ++G++LF P + RD ++Y+ V + +
Sbjct: 164 FEAMKSGLINLAISELLGASLF--ISTCVIGCIAIVKPFRVPQYLFVRDTIMYITVYVII 221
Query: 182 LVAFVWDGQIDWFEAMVLGILYILY 206
+A W G ++ + L ++Y+ +
Sbjct: 222 TMAIFW-GSLESMFCVALVLVYVAF 245
>UniRef50_Q9K8Y5 Cluster: Cation antiporter; n=1; Bacillus
halodurans|Rep: Cation antiporter - Bacillus halodurans
Length = 330
Score = 37.9 bits (84), Expect = 0.50
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 65 FLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVI 124
F+ ++V I T L AI ++Y + I E + + F++ ATS PE V
Sbjct: 3 FVWFIVAAIVTI-LTAIKLSNY----ADTIGEKSTLGGMLVGTIFLAGATSLPEITTTVS 57
Query: 125 STFLTESDMGIGTIVGSALFN 145
+ L D+ +G ++GS +FN
Sbjct: 58 AIVLNNPDLAVGNVLGSNMFN 78
>UniRef50_Q6A563 Cluster: Sodium/calcium exchanger protein; n=3;
Bacteria|Rep: Sodium/calcium exchanger protein -
Bacteroides cellulosolvens
Length = 345
Score = 37.9 bits (84), Expect = 0.50
Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 3/141 (2%)
Query: 75 TFTLLAIVCNDY-FIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDM 133
+ L IV Y F+ +E I + LKI + A +AT PE F ++I + +
Sbjct: 205 SIALTGIVSGSYIFVSNIEGISQALKISPMILALIITPIATELPEKFNSIIWIRKGKDSL 264
Query: 134 GIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDW 193
+G I G+ +F T ++ + VL + ++ +L+ ++
Sbjct: 265 ALGNISGAMVFQ--SCIPVAVGIVFTTWKLNNTAMVSCVLSLVSSVILLLWMKVKKELTP 322
Query: 194 FEAMVLGILYILYFVVMFNSM 214
+ G+LYIL+ + + N +
Sbjct: 323 LPFIFCGVLYILFIIYLTNGV 343
>UniRef50_A7Q0E3 Cluster: Chromosome chr7 scaffold_42, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr7 scaffold_42, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 560
Score = 37.9 bits (84), Expect = 0.50
Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 12/138 (8%)
Query: 286 VMGMTFLAFGGCLPE-ACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLE 344
V+ T LA G P+ S R+ ++N + +NS+ I +G+PWLI T
Sbjct: 424 VIAFTALAAGTSWPDLVASKIAAERQTTADSAIANIICSNSVNIYMGIGIPWLINTTYNF 483
Query: 345 IQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVG----------IVLG 394
I E V N+ G+ F VL + + TL +G +
Sbjct: 484 IAYREPLGVQ-NAEGLSFSLLVFFCTSICCIGVLVLRRLTLGAELGGPKIWARLTCVYFM 542
Query: 395 ILYVVFIVFAILVELGII 412
L+++F+V + L GII
Sbjct: 543 SLWIIFVVLSSLKIYGII 560
>UniRef50_Q21895 Cluster: Putative uncharacterized protein ncx-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein ncx-3 - Caenorhabditis elegans
Length = 807
Score = 37.5 bits (83), Expect = 0.66
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLPWLIRT 340
+ ++V +T +A G LP+ + I + + V N G+NS+ + LGLPW+I +
Sbjct: 664 LKDAVTAITLVALGTSLPDTFASKIAAESDDTADNAVGNVTGSNSVNVFLGLGLPWVIAS 723
Query: 341 V 341
+
Sbjct: 724 L 724
Score = 35.9 bits (79), Expect = 2.0
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 3/45 (6%)
Query: 104 VAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
VA T M++ +S PE +++I D+G GTIVGSA FN
Sbjct: 92 VANLTLMALGSSAPEILLSIIEIVGNGFKAGDLGPGTIVGSAAFN 136
>UniRef50_P57103 Cluster: Sodium/calcium exchanger 3 precursor
(Na(+)/Ca(2+)-exchange protein 3); n=109; Eumetazoa|Rep:
Sodium/calcium exchanger 3 precursor
(Na(+)/Ca(2+)-exchange protein 3) - Homo sapiens (Human)
Length = 927
Score = 37.5 bits (83), Expect = 0.66
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 780 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 839
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 840 WSVAAIYWALQGQE 853
>UniRef50_UPI00006609FB Cluster: Sodium/calcium exchanger 2
precursor (Na(+)/Ca(2+)-exchange protein 2).; n=1;
Takifugu rubripes|Rep: Sodium/calcium exchanger 2
precursor (Na(+)/Ca(2+)-exchange protein 2). - Takifugu
rubripes
Length = 953
Score = 37.1 bits (82), Expect = 0.87
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEA-CSIFIMSRRGEGGIGVSNALGANSLAILFALGLP 335
G T + ++V + F+A G LP+ S F ++ V N G+N++ + +GL
Sbjct: 806 GCTVGLRDTVTAVVFVALGTSLPDTFASKFAATQDQYADACVGNVTGSNAVNVFLGIGLA 865
Query: 336 WLIRTVSLEIQG 347
W + V +I+G
Sbjct: 866 WSVAAVYWKIKG 877
Score = 34.7 bits (76), Expect = 4.6
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI ++G GTIVGSA FN
Sbjct: 78 ETVSNLTLMALGSSAPEILLSVIEVCGHGFNAGELGPGTIVGSAAFN 124
>UniRef50_A6TJL1 Cluster: Sodium/calcium exchanger membrane region;
n=1; Alkaliphilus metalliredigens QYMF|Rep:
Sodium/calcium exchanger membrane region - Alkaliphilus
metalliredigens QYMF
Length = 335
Score = 37.1 bits (82), Expect = 0.87
Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 67 LYVVFGIYTFT-LLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVIS 125
++ + ++ F+ +L I+ ++I + + + ++ ATS PE +V +
Sbjct: 1 MFNTYALFLFSAVLVIISGMKLSKYGDVIANNTSLGHGIVGGVLIAAATSLPELVTSVSA 60
Query: 126 TFLTESDMGIGTIVGSALFN 145
+ + D+ IG + GS +FN
Sbjct: 61 SLMGAPDIAIGNVYGSNIFN 80
>UniRef50_Q7PT92 Cluster: ENSANGP00000009511; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000009511 - Anopheles gambiae
str. PEST
Length = 511
Score = 37.1 bits (82), Expect = 0.87
Identities = 28/130 (21%), Positives = 52/130 (40%), Gaps = 4/130 (3%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTV 341
+ + +T LA+G C + ++ ++ RG +G + LGA IL L + ++ +
Sbjct: 380 VSSASFAITILAWGSCWIDLITLRTLAVRGYSRLGFAACLGAPVFNILIGLCTVFCVQMI 439
Query: 342 SLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGILYVVFI 401
G V ++G VLF +F R+++ L LYV F+
Sbjct: 440 R---SGTTQIHVRDGTSGPTCAIYLFVTSMTILLSVLFT-RFEARKSIAFCLTTLYVTFL 495
Query: 402 VFAILVELGI 411
+ E +
Sbjct: 496 AYVAFCEFEV 505
>UniRef50_Q7RUV4 Cluster: Putative uncharacterized protein
B14D6.440; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein B14D6.440 - Neurospora crassa
Length = 898
Score = 37.1 bits (82), Expect = 0.87
Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 133 MGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQID 192
M +G ++G+A F + R RD++ ++V+IS + F+ D ++
Sbjct: 8 MAVGELIGAAGF--ITAVVAGSMALVREFKVQKRTFVRDIVYFIVSISFTMMFLLDQELH 65
Query: 193 WFEAMVLGILYILYFVVMF 211
+EA + YI Y +++F
Sbjct: 66 LWEANAMVGCYIFYVILVF 84
>UniRef50_Q6MGF3 Cluster: Putative uncharacterized protein
B13C5.010; n=2; Neurospora crassa|Rep: Putative
uncharacterized protein B13C5.010 - Neurospora crassa
Length = 828
Score = 37.1 bits (82), Expect = 0.87
Identities = 33/164 (20%), Positives = 65/164 (39%), Gaps = 8/164 (4%)
Query: 52 DGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMS 111
DG D+ R A +L +V T+L VC ++ + + + E K+P+ +
Sbjct: 661 DGDHPDDLSRVSAIILLLVS-----TVLVAVCAEFMVDSIHDLVETAKVPELFIGLIILP 715
Query: 112 VATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRP--VT 169
+ + E + + D+ IG VGS++ + DM
Sbjct: 716 IVGNAAEHVTAITVAMKNKMDLAIGVAVGSSI-QIALFITPLVVIIGWCMDKDMTLYFTL 774
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNS 213
+ + V+ ++ V DG+ ++ E +L Y++ +V F S
Sbjct: 775 FETVCLFVSAFIVNFLVLDGRSNYLEGALLCATYVIIALVSFYS 818
>UniRef50_Q1E9Q8 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 563
Score = 37.1 bits (82), Expect = 0.87
Identities = 34/168 (20%), Positives = 64/168 (38%), Gaps = 3/168 (1%)
Query: 44 GDSIDSFPDGIFTDEQLRQGAFLLYV-VFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
G + S P + DE + +V +F + T L VC + + +++I I +
Sbjct: 379 GHNAQSVPIQVPDDEDQEEPELHFFVALFTLAASTALVGVCAEALVSSIDVITTRGHISE 438
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+ + + E + + D+ IG VGS++
Sbjct: 439 TFVGLILLPIVGNAAEHATAITVAMKDKMDLSIGVAVGSSMQIALLVLPLIVVIGWIAGK 498
Query: 163 IDMRPVTRDVLIYMVNISVLVA--FVWDGQIDWFEAMVLGILYILYFV 208
DM I ++ ++VL+ + DG+ W E M+L LY++ V
Sbjct: 499 DDMSLYFDGFQIAVLFVAVLLVNYLIQDGKSHWLEGMLLMTLYLIISV 546
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.326 0.142 0.437
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 429,514,082
Number of Sequences: 1657284
Number of extensions: 17570614
Number of successful extensions: 56214
Number of sequences better than 10.0: 276
Number of HSP's better than 10.0 without gapping: 219
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 55185
Number of HSP's gapped (non-prelim): 921
length of query: 422
length of database: 575,637,011
effective HSP length: 103
effective length of query: 319
effective length of database: 404,936,759
effective search space: 129174826121
effective search space used: 129174826121
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 74 (33.9 bits)
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