Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000675-TA|BGIBMGA000675-PA|IPR004837|Sodium/calcium
exchanger membrane region, IPR004481|K+-dependent Na+/Ca+ exchanger
related-protein
(422 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 2... 157 5e-38
AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 2... 157 5e-38
AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 2... 157 5e-38
AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 2... 157 5e-38
AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 2... 157 5e-38
AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 2... 157 5e-38
AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/... 157 5e-38
BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 2... 154 6e-37
AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca excha... 154 6e-37
AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca excha... 153 8e-37
AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca excha... 153 1e-36
BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 2... 134 7e-31
BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 2... 134 7e-31
AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX pro... 134 7e-31
BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein. 133 1e-30
AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 133 1e-30
AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K exc... 133 1e-30
BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 2... 130 1e-29
AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 2... 130 1e-29
AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 2... 130 1e-29
AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 2... 130 1e-29
AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 2... 130 1e-29
AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 2... 130 1e-29
AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 2... 130 1e-29
AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium pot... 130 1e-29
AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium pot... 130 1e-29
AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein. 126 1e-28
AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+... 126 1e-28
AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein pr... 89 2e-17
BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein. 79 4e-14
AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens ... 78 5e-14
BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein. 59 3e-08
AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent... 58 4e-08
AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent... 47 1e-04
AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3 pr... 38 0.088
AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3 pr... 38 0.088
AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isof... 38 0.088
AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchange... 38 0.088
AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchange... 38 0.088
AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 38 0.088
AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isof... 38 0.088
AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isof... 38 0.088
AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein. 37 0.15
M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein. 36 0.27
AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchange... 36 0.27
AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchange... 36 0.27
AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchange... 36 0.27
AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein. 36 0.27
AK027652-1|BAB55268.1| 393|Homo sapiens protein ( Homo sapiens ... 36 0.36
BC012125-1|AAH12125.1| 460|Homo sapiens SLC39A8 protein protein. 34 1.1
AF193052-1|AAG22480.1| 460|Homo sapiens unknown protein. 34 1.1
AB040120-1|BAB21559.1| 460|Homo sapiens BCG induced integral me... 34 1.1
BC011551-1|AAH11551.1| 502|Homo sapiens zinc finger, C3HC-type ... 33 1.4
AK022373-1|BAB14024.1| 502|Homo sapiens protein ( Homo sapiens ... 33 1.4
AJ537494-1|CAD61161.1| 502|Homo sapiens nuclear interacting par... 33 1.4
BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein. 33 1.9
BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein. 33 1.9
AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8... 33 1.9
AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isof... 32 3.3
>AL139429-1|CAC13155.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AL136090-1|CAI17163.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AL121830-1|CAC36052.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AL121761-1|CAC12640.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AL049647-1|CAC36050.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AL034425-1|CAC36051.2| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 3 protein.
Length = 644
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 48 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 107
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 108 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 167
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 168 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 227
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 228 IVFIYDEKVSWWESLVLVLMYLIYIVIM 255
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 502 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 561
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 562 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 617
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 618 YGVFLCFSIMTEFNV 632
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 498 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 552
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 137 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 196
Query: 334 L 334
+
Sbjct: 197 V 197
>AF169257-1|AAG12988.2| 625|Homo sapiens potassium-dependent Na/Ca
exchanger NCKX3 protein.
Length = 625
Score = 157 bits (382), Expect = 5e-38
Identities = 77/208 (37%), Positives = 126/208 (60%), Gaps = 8/208 (3%)
Query: 11 KLELEDTTWHWKPWLRTR--IEVVDNVAHEVVC------ATGDSIDSFPDGIFTDEQLRQ 62
+L+L D + W+ R ++V D + E T ++ FP+ IFT+E RQ
Sbjct: 29 ELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQ 88
Query: 63 GAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVN 122
GA +L+V+ IY F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +
Sbjct: 89 GAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTS 148
Query: 123 VISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVL 182
VI F+T+ D+G+GTIVGSA+FN +A+ + RD + Y +++ L
Sbjct: 149 VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIAL 208
Query: 183 VAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ F++D ++ W+E++VL ++Y++Y V+M
Sbjct: 209 IVFIYDEKVSWWESLVLVLMYLIYIVIM 236
Score = 85.0 bits (201), Expect = 4e-16
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN++G+N IL LGLPW
Sbjct: 483 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPW 542
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T++++ + + +NS G+ + + + K+ L + +G +L
Sbjct: 543 ALQTLAVDY----GSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLL 598
Query: 397 YVVFIVFAILVELGI 411
Y VF+ F+I+ E +
Sbjct: 599 YGVFLCFSIMTEFNV 613
Score = 31.9 bits (69), Expect = 4.4
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFN 145
V +I L IP + TF++ TS P+ ++I DM + +GS +F+
Sbjct: 479 VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFD 533
Score = 31.1 bits (67), Expect = 7.7
Identities = 19/61 (31%), Positives = 28/61 (45%)
Query: 274 EKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
EK + E V G TF+A G PE + I +G +GV +G+ IL +G
Sbjct: 118 EKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIG 177
Query: 334 L 334
+
Sbjct: 178 V 178
>BC069653-1|AAH69653.1| 605|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 4 protein.
Length = 605
Score = 154 bits (373), Expect = 6e-37
Identities = 88/251 (35%), Positives = 139/251 (55%), Gaps = 15/251 (5%)
Query: 24 WLRTRIEVVDNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVC 83
W ++ N T +I FP +F++++ + GA LL+++ +Y F LAIVC
Sbjct: 42 WRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVC 101
Query: 84 NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSAL 143
+D+F+P +E ICE L + ++VA ATFM+ +S PE F +VI F+T D+G+GTIVGSA+
Sbjct: 102 DDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAV 161
Query: 144 FNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILY 203
FN + + V RD + Y +++ VL+ F++D QI W+E +VL ILY
Sbjct: 162 FNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 221
Query: 204 ILYFVVM-FN-SMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGID--NKGFNDPSP 259
+ Y ++M +N M+AF + K + A+ N N +E G D + ++DPS
Sbjct: 222 VFYILIMKYNVKMQAFFTV---------KQKSI-ANGNPVNSELEAGNDFYDGSYDDPSV 271
Query: 260 VTNGTTMTEKP 270
G + EKP
Sbjct: 272 PLLG-QVKEKP 281
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 462 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 521
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+ + + V INS G+ + + + + K+ L R +G+ + +L
Sbjct: 522 GLQTMVVNY----GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVL 577
Query: 397 YVVFIVFAILVELGI 411
Y +F+ F+I++E +
Sbjct: 578 YAIFLCFSIMIEFNV 592
Score = 33.9 bits (74), Expect = 1.1
Identities = 20/71 (28%), Positives = 33/71 (46%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL V + + V +I L IP + TF++ TS P+ ++I DM
Sbjct: 442 TATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMA 501
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 502 VSNTIGSNVFD 512
>AF520704-1|AAM76070.1| 605|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 605
Score = 154 bits (373), Expect = 6e-37
Identities = 88/251 (35%), Positives = 139/251 (55%), Gaps = 15/251 (5%)
Query: 24 WLRTRIEVVDNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVC 83
W ++ N T +I FP +F++++ + GA LL+++ +Y F LAIVC
Sbjct: 42 WRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVC 101
Query: 84 NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSAL 143
+D+F+P +E ICE L + ++VA ATFM+ +S PE F +VI F+T D+G+GTIVGSA+
Sbjct: 102 DDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAV 161
Query: 144 FNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILY 203
FN + + V RD + Y +++ VL+ F++D QI W+E +VL ILY
Sbjct: 162 FNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 221
Query: 204 ILYFVVM-FN-SMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGID--NKGFNDPSP 259
+ Y ++M +N M+AF + K + A+ N N +E G D + ++DPS
Sbjct: 222 VFYILIMKYNVKMQAFFTV---------KQKSI-ANGNPVNSELEAGNDFYDGSYDDPSV 271
Query: 260 VTNGTTMTEKP 270
G + EKP
Sbjct: 272 PLLG-QVKEKP 281
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 462 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 521
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+ + + V INS G+ + + + + K+ L R +G+ + +L
Sbjct: 522 GLQTMVVNY----GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVL 577
Query: 397 YVVFIVFAILVELGI 411
Y +F+ F+I++E +
Sbjct: 578 YAIFLCFSIMIEFNV 592
Score = 33.9 bits (74), Expect = 1.1
Identities = 20/71 (28%), Positives = 33/71 (46%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL V + + V +I L IP + TF++ TS P+ ++I DM
Sbjct: 442 TATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMA 501
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 502 VSNTIGSNVFD 512
>AF520705-1|AAM76071.1| 586|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 586
Score = 153 bits (372), Expect = 8e-37
Identities = 74/199 (37%), Positives = 118/199 (59%), Gaps = 2/199 (1%)
Query: 24 WLRTRIEVVDNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVC 83
W ++ N T +I FP +F++++ + GA LL+++ +Y F LAIVC
Sbjct: 42 WRNRKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVC 101
Query: 84 NDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSAL 143
+D+F+P +E ICE L + ++VA ATFM+ +S PE F +VI F+T D+G+GTIVGSA+
Sbjct: 102 DDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAV 161
Query: 144 FNXXXXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILY 203
FN + + V RD + Y +++ VL+ F++D QI W+E +VL ILY
Sbjct: 162 FNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 221
Query: 204 ILYFVVM-FN-SMKAFVLI 220
+ Y ++M +N M+AF +
Sbjct: 222 VFYILIMKYNVKMQAFFTV 240
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 443 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 502
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+ + + V INS G+ + + + + K+ L R +G+ + +L
Sbjct: 503 GLQTMVVNY----GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVL 558
Query: 397 YVVFIVFAILVELGI 411
Y +F+ F+I++E +
Sbjct: 559 YAIFLCFSIMIEFNV 573
Score = 33.9 bits (74), Expect = 1.1
Identities = 20/71 (28%), Positives = 33/71 (46%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL V + + V +I L IP + TF++ TS P+ ++I DM
Sbjct: 423 TATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMA 482
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 483 VSNTIGSNVFD 493
>AF520706-1|AAM76072.1| 558|Homo sapiens K-dependent Na/Ca
exchanger NCKX4 protein.
Length = 558
Score = 153 bits (371), Expect = 1e-36
Identities = 86/232 (37%), Positives = 135/232 (58%), Gaps = 15/232 (6%)
Query: 43 TGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQ 102
T +I FP +F++++ + GA LL+++ +Y F LAIVC+D+F+P +E ICE L + +
Sbjct: 14 TDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLSE 73
Query: 103 NVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIA 162
+VA ATFM+ +S PE F +VI F+T D+G+GTIVGSA+FN +
Sbjct: 74 DVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVR 133
Query: 163 IDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN-SMKAFVLI 220
+ V RD + Y +++ VL+ F++D QI W+E +VL ILY+ Y ++M +N M+AF +
Sbjct: 134 LTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTV 193
Query: 221 DKIWAACCKKNNGVTASLNDNNVSVEEGID--NKGFNDPSPVTNGTTMTEKP 270
K + A+ N N +E G D + ++DPS G + EKP
Sbjct: 194 ---------KQKSI-ANGNPVNSELEAGNDFYDGSYDDPSVPLLG-QVKEKP 234
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 415 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 474
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+ + + V INS G+ + + + + K+ L R +G+ + +L
Sbjct: 475 GLQTMVVNY----GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVL 530
Query: 397 YVVFIVFAILVELGI 411
Y +F+ F+I++E +
Sbjct: 531 YAIFLCFSIMIEFNV 545
Score = 33.9 bits (74), Expect = 1.1
Identities = 20/71 (28%), Positives = 33/71 (46%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL V + + V +I L IP + TF++ TS P+ ++I DM
Sbjct: 395 TATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMA 454
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 455 VSNTIGSNVFD 465
>BC113630-1|AAI13631.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 134 bits (323), Expect = 7e-31
Identities = 59/179 (32%), Positives = 102/179 (56%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP+G FT ++ R G ++Y + +Y F ++IVC++YF+P +E+I E L + Q+VA TF
Sbjct: 54 FPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTF 113
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ +S PE + F+T+ D+GI TI+GSA++N T + P+
Sbjct: 114 MAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLF 173
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACC 228
RD Y ++ + ++ ++D Q+ W+E +L ++Y LY +V+ +K I K + CC
Sbjct: 174 RDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCC 232
Score = 78.6 bits (185), Expect = 4e-14
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LG+PW
Sbjct: 360 GETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPW 418
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T I G+ V NS G+ + ++ + + L R +GIV +
Sbjct: 419 FIKTAF--INGSAPAEV--NSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLS 474
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L ELGII + +
Sbjct: 475 YLGLATLSVLYELGIIGNNKI 495
Score = 37.9 bits (84), Expect = 0.067
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX--- 147
V + E L+IP V T ++ TS P+ +V+ + DM + IVGS +F+
Sbjct: 356 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCLG 415
Query: 148 --XXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
P ++ R +T + +NIS++ F+ W LGI+ +L
Sbjct: 416 IPWFIKTAFINGSAPAEVNSRGLT--YITISLNISIIFLFLAVHFNGWKLDRKLGIVCLL 473
Query: 206 YFV 208
++
Sbjct: 474 SYL 476
Score = 35.1 bits (77), Expect = 0.47
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA---NSLAILFALGLPWLI 338
+ + V G TF+A G PE + F+ +G IG+S LG+ N L I A GL L
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL--LS 161
Query: 339 RTVS 342
TVS
Sbjct: 162 NTVS 165
>BC113628-1|AAI13629.1| 500|Homo sapiens solute carrier family 24,
member 5 protein.
Length = 500
Score = 134 bits (323), Expect = 7e-31
Identities = 59/179 (32%), Positives = 102/179 (56%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP+G FT ++ R G ++Y + +Y F ++IVC++YF+P +E+I E L + Q+VA TF
Sbjct: 54 FPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTF 113
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ +S PE + F+T+ D+GI TI+GSA++N T + P+
Sbjct: 114 MAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLF 173
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACC 228
RD Y ++ + ++ ++D Q+ W+E +L ++Y LY +V+ +K I K + CC
Sbjct: 174 RDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCC 232
Score = 78.6 bits (185), Expect = 4e-14
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LG+PW
Sbjct: 360 GETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPW 418
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T I G+ V NS G+ + ++ + + L R +GIV +
Sbjct: 419 FIKTAF--INGSAPAEV--NSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLS 474
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L ELGII + +
Sbjct: 475 YLGLATLSVLYELGIIGNNKI 495
Score = 37.9 bits (84), Expect = 0.067
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX--- 147
V + E L+IP V T ++ TS P+ +V+ + DM + IVGS +F+
Sbjct: 356 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCLG 415
Query: 148 --XXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
P ++ R +T + +NIS++ F+ W LGI+ +L
Sbjct: 416 IPWFIKTAFINGSAPAEVNSRGLT--YITISLNISIIFLFLAVHFNGWKLDRKLGIVCLL 473
Query: 206 YFV 208
++
Sbjct: 474 SYL 476
Score = 35.1 bits (77), Expect = 0.47
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA---NSLAILFALGLPWLI 338
+ + V G TF+A G PE + F+ +G IG+S LG+ N L I A GL L
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL--LS 161
Query: 339 RTVS 342
TVS
Sbjct: 162 NTVS 165
>AF348468-1|AAQ15116.1| 500|Homo sapiens ion transporter JSX
protein.
Length = 500
Score = 134 bits (323), Expect = 7e-31
Identities = 59/179 (32%), Positives = 102/179 (56%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
FP+G FT ++ R G ++Y + +Y F ++IVC++YF+P +E+I E L + Q+VA TF
Sbjct: 54 FPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTF 113
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ +S PE + F+T+ D+GI TI+GSA++N T + P+
Sbjct: 114 MAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLF 173
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACC 228
RD Y ++ + ++ ++D Q+ W+E +L ++Y LY +V+ +K I K + CC
Sbjct: 174 RDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCC 232
Score = 78.6 bits (185), Expect = 4e-14
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LG+PW
Sbjct: 360 GETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPW 418
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T I G+ V NS G+ + ++ + + L R +GIV +
Sbjct: 419 FIKTAF--INGSAPAEV--NSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLS 474
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L ELGII + +
Sbjct: 475 YLGLATLSVLYELGIIGNNKI 495
Score = 37.9 bits (84), Expect = 0.067
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX--- 147
V + E L+IP V T ++ TS P+ +V+ + DM + IVGS +F+
Sbjct: 356 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCLG 415
Query: 148 --XXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
P ++ R +T + +NIS++ F+ W LGI+ +L
Sbjct: 416 IPWFIKTAFINGSAPAEVNSRGLT--YITISLNISIIFLFLAVHFNGWKLDRKLGIVCLL 473
Query: 206 YFV 208
++
Sbjct: 474 SYL 476
Score = 35.1 bits (77), Expect = 0.47
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGA---NSLAILFALGLPWLI 338
+ + V G TF+A G PE + F+ +G IG+S LG+ N L I A GL L
Sbjct: 104 LSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL--LS 161
Query: 339 RTVS 342
TVS
Sbjct: 162 NTVS 165
>BC117263-1|AAI17264.1| 1069|Homo sapiens SLC24A1 protein protein.
Length = 1069
Score = 133 bits (321), Expect = 1e-30
Identities = 73/221 (33%), Positives = 125/221 (56%), Gaps = 3/221 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 440 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 499
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 500 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 559
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++ +L+ F D I W+E+++L + Y Y F + +N + +++
Sbjct: 560 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPV 619
Query: 229 KKNNGV--TASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMT 267
K + + D ++V+E DNK PS +T G++ T
Sbjct: 620 AKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
Score = 64.9 bits (151), Expect = 5e-10
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Query: 270 PAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAIL 329
P + + G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I
Sbjct: 926 PDVRRQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDIT 985
Query: 330 FALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTV 389
L +PWL+ ++ I G + V ++S G+ + K+ + + +
Sbjct: 986 VGLPVPWLLFSL---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKIL 1040
Query: 390 GIVLGILYVVFIVFAILVELGII 412
G + +LY VF++ ++++E II
Sbjct: 1041 GFTMFLLYFVFLIISVMLEDRII 1063
Score = 35.1 bits (77), Expect = 0.47
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 35.1 bits (77), Expect = 0.47
Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%)
Query: 73 IYTFTLLAIVCNDYFIPCVEL-ICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTES 131
IY F L + +P V + E + I + + T ++ TS P+ +VI
Sbjct: 910 IYLFLLPIVFPLWLTVPDVRRQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLG 969
Query: 132 DMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVTRDVLI-YMVNISVLVAFVWD-- 188
DM + + VGS +F+ + PV+ + L +V + +++ FV
Sbjct: 970 DMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSI 1029
Query: 189 GQIDWFEAMVLGI-LYILYFVVMFNSM 214
W +LG +++LYFV + S+
Sbjct: 1030 ASCKWRMNKILGFTMFLLYFVFLIISV 1056
>AF062922-1|AAC77912.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger protein.
Length = 1099
Score = 133 bits (321), Expect = 1e-30
Identities = 73/221 (33%), Positives = 125/221 (56%), Gaps = 3/221 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 440 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 499
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 500 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 559
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++ +L+ F D I W+E+++L + Y Y F + +N + +++
Sbjct: 560 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPV 619
Query: 229 KKNNGV--TASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMT 267
K + + D ++V+E DNK PS +T G++ T
Sbjct: 620 AKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
Score = 63.3 bits (147), Expect = 2e-09
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 963 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1022
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ I G + V ++S G+ + K+ + + +G + +L
Sbjct: 1023 LLFSL---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1077
Query: 397 YVVFIVFAILVELGII 412
Y VF++ ++++E II
Sbjct: 1078 YFVFLIISVMLEDRII 1093
Score = 35.1 bits (77), Expect = 0.47
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 34.3 bits (75), Expect = 0.82
Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023
Query: 156 XXXTPIAIDMRPVTRDVLI-YMVNISVLVAFVWD--GQIDWFEAMVLGI-LYILYFVVMF 211
+ PV+ + L +V + +++ FV W +LG +++LYFV +
Sbjct: 1024 LFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLI 1083
Query: 212 NSM 214
S+
Sbjct: 1084 ISV 1086
>AF062921-1|AAC16732.1| 1099|Homo sapiens retinal rod Na-Ca+K
exchanger splice variant protein.
Length = 1099
Score = 133 bits (321), Expect = 1e-30
Identities = 73/221 (33%), Positives = 125/221 (56%), Gaps = 3/221 (1%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 440 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 499
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 500 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 559
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILY-FVVMFNSMKAFVLIDKIWAACC 228
RDV Y++++ +L+ F D I W+E+++L + Y Y F + +N + +++
Sbjct: 560 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPV 619
Query: 229 KKNNGV--TASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMT 267
K + + D ++V+E DNK PS +T G++ T
Sbjct: 620 AKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
Score = 63.3 bits (147), Expect = 2e-09
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 963 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1022
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ I G + V ++S G+ + K+ + + +G + +L
Sbjct: 1023 LLFSL---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1077
Query: 397 YVVFIVFAILVELGII 412
Y VF++ ++++E II
Sbjct: 1078 YFVFLIISVMLEDRII 1093
Score = 35.1 bits (77), Expect = 0.47
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 34.3 bits (75), Expect = 0.82
Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1023
Query: 156 XXXTPIAIDMRPVTRDVLI-YMVNISVLVAFVWD--GQIDWFEAMVLGI-LYILYFVVMF 211
+ PV+ + L +V + +++ FV W +LG +++LYFV +
Sbjct: 1024 LFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLI 1083
Query: 212 NSM 214
S+
Sbjct: 1084 ISV 1086
>BC069622-1|AAH69622.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 585
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 586 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 642
Query: 209 VMFNSM 214
+ S+
Sbjct: 643 FLVVSV 648
>AL158206-3|CAH73021.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 508 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 567
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 568 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 622
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 623 YFVFLVVSVLLE 634
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 568
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 569 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 625
Query: 209 VMFNSM 214
+ S+
Sbjct: 626 FLVVSV 631
>AL158206-2|CAH73020.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 585
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 586 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 642
Query: 209 VMFNSM 214
+ S+
Sbjct: 643 FLVVSV 648
>AL158077-2|CAH74108.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 585
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 586 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 642
Query: 209 VMFNSM 214
+ S+
Sbjct: 643 FLVVSV 648
>AL158077-1|CAH74109.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 508 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 567
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 568 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 622
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 623 YFVFLVVSVLLE 634
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 568
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 569 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 625
Query: 209 VMFNSM 214
+ S+
Sbjct: 626 FLVVSV 631
>AL133281-2|CAH71736.1| 661|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 661
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 585
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 586 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 642
Query: 209 VMFNSM 214
+ S+
Sbjct: 643 FLVVSV 648
>AL133281-1|CAH71737.1| 644|Homo sapiens solute carrier family 24
(sodium/potassium/calcium exchanger), member 2 protein.
Length = 644
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 508 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 567
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 568 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 622
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 623 YFVFLVVSVLLE 634
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 568
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 569 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 625
Query: 209 VMFNSM 214
+ S+
Sbjct: 626 FLVVSV 631
>AF177987-1|AAF25811.1| 644|Homo sapiens cone sodium-calcium
potassium exchanger splice variant protein.
Length = 644
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 508 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 567
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 568 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 622
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 623 YFVFLVVSVLLE 634
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 509 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 568
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 569 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 625
Query: 209 VMFNSM 214
+ S+
Sbjct: 626 FLVVSV 631
>AF097366-1|AAF21810.1| 661|Homo sapiens cone sodium-calcium
potassium exchanger protein.
Length = 661
Score = 130 bits (313), Expect = 1e-29
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Query: 42 ATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIP 101
+T + +P IF+ E+ R+GA +L+V+ IY F LAIVC+++F+P + +I E L I
Sbjct: 112 STDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGIS 171
Query: 102 QNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPI 161
+VA ATFM+ S PE F ++I F+ S++GIGTIVGSA+FN +
Sbjct: 172 DDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREIL 231
Query: 162 AIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN 212
+ P+ RDV Y+V++ +L+ F D I W+E+++L Y Y V M FN
Sbjct: 232 NLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFN 283
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L LPW
Sbjct: 525 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPW 584
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ TV Q V ++S G+ + + + K+ + + +G ++ L
Sbjct: 585 LLYTVIHRFQ-----PVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 397 YVVFIVFAILVE 408
Y VF+V ++L+E
Sbjct: 640 YFVFLVVSVLLE 651
Score = 34.7 bits (76), Expect = 0.62
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGL 334
I + V G TF+A GG PE + I +G+ +G+ ILF +G+
Sbjct: 170 ISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 31.5 bits (68), Expect = 5.8
Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXX-----X 150
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 526 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWL 585
Query: 151 XXXXXXXXTPIAIDMRPV-TRDVLIYMVNISVLVAFVWDGQIDWFEAMVLG-ILYILYFV 208
P+A+ + VL++++ + V+++ W +LG I++ LYFV
Sbjct: 586 LYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSI---ALCKWRMNKILGFIMFGLYFV 642
Query: 209 VMFNSM 214
+ S+
Sbjct: 643 FLVVSV 648
>AB014602-1|BAA31677.2| 988|Homo sapiens KIAA0702 protein protein.
Length = 988
Score = 126 bits (305), Expect = 1e-28
Identities = 60/161 (37%), Positives = 98/161 (60%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 443 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 502
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 503 MAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 562
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
RDV Y++++ +L+ F D I W+E+++L + Y Y M
Sbjct: 563 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 603
Score = 35.1 bits (77), Expect = 0.47
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 493 ISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 544
>AF026132-1|AAB97832.1| 1081|Homo sapiens retinal rod Na+/Ca+, K+
exchanger protein.
Length = 1081
Score = 126 bits (304), Expect = 1e-28
Identities = 60/161 (37%), Positives = 98/161 (60%)
Query: 50 FPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATF 109
+P +F+ E+ RQG +L+V +Y F LAIVC++YF+P + +I + L+I ++VA ATF
Sbjct: 440 YPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATF 499
Query: 110 MSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXTPIAIDMRPVT 169
M+ S PE F ++I F++ S++GIGTIVGSA+FN + + P+
Sbjct: 500 MAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLF 559
Query: 170 RDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
RDV Y++++ +L+ F D I W+E+++L + Y Y M
Sbjct: 560 RDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
Score = 63.3 bits (147), Expect = 2e-09
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T I E +MG+T LA G +P+ + I++R+G G + VS+++G+N I L +PW
Sbjct: 945 GETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW 1004
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
L+ ++ I G + V ++S G+ + K+ + + +G + +L
Sbjct: 1005 LLFSL---INGLQ--PVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1059
Query: 397 YVVFIVFAILVELGII 412
Y VF++ ++++E II
Sbjct: 1060 YFVFLIISVMLEDRII 1075
Score = 35.1 bits (77), Expect = 0.47
Identities = 18/52 (34%), Positives = 25/52 (48%)
Query: 282 IPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALG 333
I E V G TF+A GG PE + I +G+ +G+ ILF +G
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIG 541
Score = 34.3 bits (75), Expect = 0.82
Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Query: 96 EDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXXXXXXXXXX 155
E + I + + T ++ TS P+ +VI DM + + VGS +F+
Sbjct: 946 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWL 1005
Query: 156 XXXTPIAIDMRPVTRDVLI-YMVNISVLVAFVWD--GQIDWFEAMVLGI-LYILYFVVMF 211
+ PV+ + L +V + +++ FV W +LG +++LYFV +
Sbjct: 1006 LFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLI 1065
Query: 212 NSM 214
S+
Sbjct: 1066 ISV 1068
>AL834225-1|CAD38903.1| 316|Homo sapiens hypothetical protein
protein.
Length = 316
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G+T IP+ +MG+TFLA G +P+ + I++R+G G + VSN +G+N IL LG+PW
Sbjct: 173 GYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 232
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
++T+ + + V INS G+ + + + + K+ L R +G+ + +L
Sbjct: 233 GLQTMVVNY----GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVL 288
Query: 397 YVVFIVFAILVELGI 411
Y +F+ F+I++E +
Sbjct: 289 YAIFLCFSIMIEFNV 303
Score = 33.9 bits (74), Expect = 1.1
Identities = 20/71 (28%), Positives = 33/71 (46%)
Query: 75 TFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMG 134
T TL V + + V +I L IP + TF++ TS P+ ++I DM
Sbjct: 153 TATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMA 212
Query: 135 IGTIVGSALFN 145
+ +GS +F+
Sbjct: 213 VSNTIGSNVFD 223
>BC073944-1|AAH73944.1| 218|Homo sapiens SLC24A5 protein protein.
Length = 218
Score = 78.6 bits (185), Expect = 4e-14
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 5/141 (3%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPW 336
G T IP++VMG+T LA G +P+ + +++R+G+G + +SN +G+N +L LG+PW
Sbjct: 78 GETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPW 136
Query: 337 LIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGKFTLRRTVGIVLGIL 396
I+T I G+ V NS G+ + ++ + + L R +GIV +
Sbjct: 137 FIKTAF--INGSAPAEV--NSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLS 192
Query: 397 YVVFIVFAILVELGIIFDRNV 417
Y+ ++L ELGII + +
Sbjct: 193 YLGLATLSVLYELGIIGNNKI 213
Score = 37.9 bits (84), Expect = 0.067
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 91 VELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNXX--- 147
V + E L+IP V T ++ TS P+ +V+ + DM + IVGS +F+
Sbjct: 74 VTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLCLG 133
Query: 148 --XXXXXXXXXXXTPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYIL 205
P ++ R +T + +NIS++ F+ W LGI+ +L
Sbjct: 134 IPWFIKTAFINGSAPAEVNSRGLT--YITISLNISIIFLFLAVHFNGWKLDRKLGIVCLL 191
Query: 206 YFV 208
++
Sbjct: 192 SYL 194
>AK096171-1|BAC04715.1| 352|Homo sapiens protein ( Homo sapiens
cDNA FLJ38852 fis, clone MESAN2010312, weakly similar to
Homo sapiens sodium/calcium exchanger NCKX3 (SLC24A3)
mRNA. ).
Length = 352
Score = 78.2 bits (184), Expect = 5e-14
Identities = 33/63 (52%), Positives = 46/63 (73%)
Query: 76 FTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGI 135
F LAIVC+D+F+P +E ICE L + ++VA ATFM+ +S PE F +VI F+T D+G+
Sbjct: 2 FYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGV 61
Query: 136 GTI 138
GTI
Sbjct: 62 GTI 64
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 15/104 (14%)
Query: 171 DVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVM-FN-SMKAFVLIDKIWAACC 228
DV + +++ VL+ F++D QI W+E +VL ILY+ Y ++M +N M+AF +
Sbjct: 58 DVGVGTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTV-------- 109
Query: 229 KKNNGVTASLNDNNVSVEEGID--NKGFNDPSPVTNGTTMTEKP 270
K + A+ N N +E G D + ++DPS G + EKP
Sbjct: 110 -KQKSI-ANGNPVNSELEAGNDFYDGSYDDPSVPLLG-QVKEKP 150
>BC098360-1|AAH98360.1| 584|Homo sapiens SLC24A6 protein protein.
Length = 584
Score = 59.3 bits (137), Expect = 3e-08
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A LYV + +Y F +L + +F P + I LK+ NVA TF++ P+ F
Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIF--- 155
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT---PIAIDMRPVTRDVLIYMVNIS 180
S + SD + ALF T P RP RD++ YMV +
Sbjct: 156 -SALVAFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVF 214
Query: 181 VLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ ++ G++ A+ LY+ Y V +
Sbjct: 215 LTFLMLFRGRVTLAWALGYLGLYVFYVVTV 244
Score = 47.2 bits (107), Expect = 1e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE I G F + +V+G+T LA+G + +A S F ++R+G + S G
Sbjct: 438 TEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIF 497
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK--FT 384
IL +GL L++ +T V + G+ + ++ + F
Sbjct: 498 NILVGVGLGCLLQI------SRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQ 551
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGII 412
L R G L + Y+ F+V A+L E G+I
Sbjct: 552 LSRVYGFCLLLFYLNFLVVALLTEFGVI 579
>AY601759-1|AAT35807.1| 584|Homo sapiens Na+/Ca2+ K+ independent
exchanger protein.
Length = 584
Score = 58.4 bits (135), Expect = 4e-08
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A LYV + +Y F +L + +F P + I LK+ NVA TF++ P+ F
Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAIPTTLKLSHNVAGVTFLAFGNGAPDIF--- 155
Query: 124 ISTFLTESDMGIGTIVGSALFNXXXXXXXXXXXXXT---PIAIDMRPVTRDVLIYMVNIS 180
S + SD + ALF T P RP RD++ YMV +
Sbjct: 156 -SALVAFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVF 214
Query: 181 VLVAFVWDGQIDWFEAMVLGILYILYFVVM 210
+ ++ G++ A+ LY+ Y V +
Sbjct: 215 LTFLMLFRGRVTLAWALGYLGLYVFYVVTV 244
Score = 47.2 bits (107), Expect = 1e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE I G F + +V+G+T LA+G + +A S F ++R+G + S G
Sbjct: 438 TEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIF 497
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK--FT 384
IL +GL L++ +T V + G+ + ++ + F
Sbjct: 498 NILVGVGLGCLLQI------SRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQ 551
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGII 412
L R G L + Y+ F+V A+L E G+I
Sbjct: 552 LSRVYGFCLLLFYLNFLVVALLTEFGVI 579
>AY601760-1|AAT35808.1| 528|Homo sapiens Na+/Ca2+ K+ independent
exchanger short splice isoform protein.
Length = 528
Score = 47.2 bits (107), Expect = 1e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE I G F + +V+G+T LA+G + +A S F ++R+G + S G
Sbjct: 382 TEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIF 441
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK--FT 384
IL +GL L++ +T V + G+ + ++ + F
Sbjct: 442 NILVGVGLGCLLQI------SRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQ 495
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGII 412
L R G L + Y+ F+V A+L E G+I
Sbjct: 496 LSRVYGFCLLLFYLNFLVVALLTEFGVI 523
Score = 43.2 bits (97), Expect = 0.002
Identities = 19/62 (30%), Positives = 32/62 (51%)
Query: 64 AFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNV 123
A LYV + +Y F +L + +F P + I LK+ NVA TF++ P+ F +
Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSAL 158
Query: 124 IS 125
++
Sbjct: 159 VA 160
>AK025886-1|BAB15271.1| 389|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22233 fis, clone HRC02016. ).
Length = 389
Score = 47.2 bits (107), Expect = 1e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 267 TEKPAIDEKNGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSL 326
TE I G F + +V+G+T LA+G + +A S F ++R+G + S G
Sbjct: 243 TEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIF 302
Query: 327 AILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFXXXXXXXXXXXXWIVLFIGK--FT 384
IL +GL L++ +T V + G+ + ++ + F
Sbjct: 303 NILVGVGLGCLLQI------SRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQ 356
Query: 385 LRRTVGIVLGILYVVFIVFAILVELGII 412
L R G L + Y+ F+V A+L E G+I
Sbjct: 357 LSRVYGFCLLLFYLNFLVVALLTEFGVI 384
>AJ745102-1|CAG33740.1| 298|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 298
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 151 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 210
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 211 WSVAAIYWALQGQE 224
>AJ745101-1|CAG33739.1| 284|Homo sapiens Na+/Ca2+ exchanger 3
protein.
Length = 284
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 137 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 196
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 197 WSVAAIYWALQGQE 210
>AJ508602-1|CAD48420.1| 771|Homo sapiens Na+/Ca2+ exchanger isoform
4 protein.
Length = 771
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 624 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 683
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 684 WSVAAIYWALQGQE 697
>AJ304853-1|CAC40985.1| 924|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 924
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 777 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 836
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 837 WSVAAIYWALQGQE 850
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
>AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 925
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 778 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 837
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 838 WSVAAIYWALQGQE 851
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
>AF510502-1|AAN60791.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 3 protein.
Length = 927
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 780 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 839
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 840 WSVAAIYWALQGQE 853
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
>AF510501-1|AAN60790.1| 921|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 2 protein.
Length = 921
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 774 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 833
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 834 WSVAAIYWALQGQE 847
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
>AF508982-1|AAM90955.1| 927|Homo sapiens Na+/Ca2+ exchanger isoform
3 protein.
Length = 927
Score = 37.5 bits (83), Expect = 0.088
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+AFG +P+ + + + + N G+N++ + +GL
Sbjct: 780 GCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLA 839
Query: 336 WLIRTVSLEIQGAE 349
W + + +QG E
Sbjct: 840 WSVAAIYWALQGQE 853
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
>AB029010-1|BAA83039.1| 952|Homo sapiens KIAA1087 protein protein.
Length = 952
Score = 36.7 bits (81), Expect = 0.15
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + LG+
Sbjct: 805 GCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVA 864
Query: 336 WLIRTVSLEIQG 347
W + V +QG
Sbjct: 865 WSVAAVYWAVQG 876
Score = 34.3 bits (75), Expect = 0.82
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI ++G GTIVGSA FN
Sbjct: 157 ETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFN 203
>M91368-1|AAA35702.1| 973|Homo sapiens Na+/Ca+ exchanger protein.
Length = 973
Score = 35.9 bits (79), Expect = 0.27
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI T D+G TIVGSA FN
Sbjct: 132 ETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFN 178
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 826 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 885
Query: 336 WLIRTV 341
W I +
Sbjct: 886 WSIAAI 891
>AF128524-1|AAD26362.1| 960|Homo sapiens sodium-calcium exchanger
isoform NCX1.7 precursor protein.
Length = 960
Score = 35.9 bits (79), Expect = 0.27
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI T D+G TIVGSA FN
Sbjct: 132 ETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFN 178
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 813 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 872
Query: 336 WLIRTV 341
W I +
Sbjct: 873 WSIAAI 878
>AF108389-1|AAF08988.1| 937|Homo sapiens sodium/calcium exchanger
isoform NaCa3 protein.
Length = 937
Score = 35.9 bits (79), Expect = 0.27
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI T D+G TIVGSA FN
Sbjct: 132 ETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFN 178
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 790 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 849
Query: 336 WLIRTV 341
W I +
Sbjct: 850 WSIAAI 855
>AF108388-1|AAF08987.1| 960|Homo sapiens sodium/calcium exchanger
isoform NaCa7 protein.
Length = 960
Score = 35.9 bits (79), Expect = 0.27
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI T D+G TIVGSA FN
Sbjct: 132 ETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFN 178
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 813 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 872
Query: 336 WLIRTV 341
W I +
Sbjct: 873 WSIAAI 878
>AC007281-1|AAF19237.1| 603|Homo sapiens unknown protein.
Length = 603
Score = 35.9 bits (79), Expect = 0.27
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE ++VI T D+G TIVGSA FN
Sbjct: 132 ETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFN 178
>AK027652-1|BAB55268.1| 393|Homo sapiens protein ( Homo sapiens
cDNA FLJ14746 fis, clone NT2RP3002810, weakly similar to
HISTIDINE-RICH PROTEIN KE4. ).
Length = 393
Score = 35.5 bits (78), Expect = 0.36
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 11/106 (10%)
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNV 243
AF +D ++D + + + Y + F M +L K + NG T NDN
Sbjct: 118 AFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLL--KTYG-----QNGHTHFGNDNFG 170
Query: 244 SVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGM 289
EE K P NG T PA+ E NGH F SV+ +
Sbjct: 171 PQEETHQPKAL----PAINGVTCYANPAVTEANGHIHFDNVSVVSL 212
>BC012125-1|AAH12125.1| 460|Homo sapiens SLC39A8 protein protein.
Length = 460
Score = 33.9 bits (74), Expect = 1.1
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 11/106 (10%)
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNV 243
AF +D ++D + + + Y + F M +L K + NG T NDN
Sbjct: 185 AFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLL--KTYG-----QNGHTHFGNDNFG 237
Query: 244 SVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGM 289
E+ K P NG T PA+ E NGH F SV+ +
Sbjct: 238 PQEKTHQPKAL----PAINGVTCYANPAVTEANGHIHFDNVSVVSL 279
>AF193052-1|AAG22480.1| 460|Homo sapiens unknown protein.
Length = 460
Score = 33.9 bits (74), Expect = 1.1
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 11/106 (10%)
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNV 243
AF +D ++D + + + Y + F M +L K + NG T NDN
Sbjct: 185 AFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLL--KTYG-----QNGHTHFGNDNFG 237
Query: 244 SVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGM 289
E+ K P NG T PA+ E NGH F SV+ +
Sbjct: 238 PQEKTHQPKAL----PAINGVTCYANPAVTEANGHIHFDNVSVVSL 279
>AB040120-1|BAB21559.1| 460|Homo sapiens BCG induced integral
membrane protein BIGM103 protein.
Length = 460
Score = 33.9 bits (74), Expect = 1.1
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 11/106 (10%)
Query: 184 AFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNV 243
AF +D ++D + + + Y + F M +L K + NG T NDN
Sbjct: 185 AFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLL--KTYG-----QNGHTHFGNDNFG 237
Query: 244 SVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNGHTFFIPESVMGM 289
E+ K P NG T PA+ E NGH F SV+ +
Sbjct: 238 PQEKTHQPKAL----PAINGVTCYANPAVTEANGHIHFDNVSVVSL 279
>BC011551-1|AAH11551.1| 502|Homo sapiens zinc finger, C3HC-type
containing 1 protein.
Length = 502
Score = 33.5 bits (73), Expect = 1.4
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 215 KAFVL-IDKIWAACCKKNNGVTASLN---DNNVSVEEG-IDNKGFNDPSPVTNGTTMTEK 269
+AF + ++K W A + G + D ++ EEG +D K + S NG+ E+
Sbjct: 8 QAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAKDTSATSQSVNGSPQAEQ 67
Query: 270 PAIDEKNGHTFF 281
P+++ + FF
Sbjct: 68 PSLESTSKEAFF 79
>AK022373-1|BAB14024.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ12311 fis, clone MAMMA1002011. ).
Length = 502
Score = 33.5 bits (73), Expect = 1.4
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 215 KAFVL-IDKIWAACCKKNNGVTASLN---DNNVSVEEG-IDNKGFNDPSPVTNGTTMTEK 269
+AF + ++K W A + G + D ++ EEG +D K + S NG+ E+
Sbjct: 8 QAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAKDTSATSQSVNGSPQAEQ 67
Query: 270 PAIDEKNGHTFF 281
P+++ + FF
Sbjct: 68 PSLESTSKEAFF 79
>AJ537494-1|CAD61161.1| 502|Homo sapiens nuclear interacting
partner of ALK protein.
Length = 502
Score = 33.5 bits (73), Expect = 1.4
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 215 KAFVL-IDKIWAACCKKNNGVTASLN---DNNVSVEEG-IDNKGFNDPSPVTNGTTMTEK 269
+AF + ++K W A + G + D ++ EEG +D K + S NG+ E+
Sbjct: 8 QAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAKDTSATSQSVNGSPQAEQ 67
Query: 270 PAIDEKNGHTFF 281
P+++ + FF
Sbjct: 68 PSLESTSKEAFF 79
>BC098308-1|AAH98308.1| 335|Homo sapiens SLC8A1 protein protein.
Length = 335
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 188 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 247
Query: 336 WLIRTV 341
W I +
Sbjct: 248 WSIAAI 253
>BC098285-1|AAH98285.1| 384|Homo sapiens SLC8A1 protein protein.
Length = 384
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 237 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 296
Query: 336 WLIRTV 341
W I +
Sbjct: 297 WSIAAI 302
>AB209075-1|BAD92312.1| 411|Homo sapiens solute carrier family 8
(sodium/calcium exchanger), member 1 variant protein.
Length = 411
Score = 33.1 bits (72), Expect = 1.9
Identities = 14/66 (21%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 277 GHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGE-GGIGVSNALGANSLAILFALGLP 335
G T + +SV + F+A G +P+ + + + + + + N G+N++ + +G+
Sbjct: 264 GCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVA 323
Query: 336 WLIRTV 341
W I +
Sbjct: 324 WSIAAI 329
>AF510503-1|AAN60792.1| 620|Homo sapiens Na+/Ca2+ exchanger isoform
3 splice variant 4 protein.
Length = 620
Score = 32.3 bits (70), Expect = 3.3
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 102 QNVAAATFMSVATSCPEFFVNVISTF---LTESDMGIGTIVGSALFN 145
+ V+ T M++ +S PE +++I D+G TIVGSA FN
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFN 177
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.326 0.142 0.437
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 55,648,573
Number of Sequences: 224733
Number of extensions: 2203973
Number of successful extensions: 4922
Number of sequences better than 10.0: 60
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 4711
Number of HSP's gapped (non-prelim): 175
length of query: 422
length of database: 73,234,838
effective HSP length: 92
effective length of query: 330
effective length of database: 52,559,402
effective search space: 17344602660
effective search space used: 17344602660
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 67 (31.1 bits)
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