Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000672-TA|BGIBMGA000672-PA|IPR002020|Citrate synthase,
IPR010109|Citrate synthase, eukaryotic
(465 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC072016-1|AAH72016.1| 466|Homo sapiens citrate synthase protein. 738 0.0
BC010106-1|AAH10106.1| 466|Homo sapiens CS protein protein. 738 0.0
AK074956-1|BAC11314.1| 466|Homo sapiens protein ( Homo sapiens ... 738 0.0
AF053631-1|AAQ13428.1| 466|Homo sapiens citrate synthase protein. 736 0.0
AF047042-1|AAC25560.1| 466|Homo sapiens citrate synthase protein. 733 0.0
BC000105-1|AAH00105.3| 409|Homo sapiens CS protein protein. 699 0.0
BT007414-1|AAP36082.1| 264|Homo sapiens citrate synthase protein. 455 e-127
DQ403132-1|ABD77265.1| 224|Homo sapiens citrate synthase protein. 402 e-111
U18197-1|AAB60340.1| 1101|Homo sapiens ATP:citrate lyase protein. 38 0.075
BC006195-1|AAH06195.1| 1101|Homo sapiens ATP citrate lyase protein. 38 0.075
AK095084-1|BAC04484.1| 701|Homo sapiens mRNA. protein. 38 0.075
AB210035-1|BAE06117.1| 1137|Homo sapiens ACLY variant protein pr... 38 0.075
X64330-1|CAA45614.1| 1105|Homo sapiens ATP-citrate (pro-S-)-lyas... 35 0.53
AK024452-1|BAB15742.1| 1051|Homo sapiens FLJ00044 protein protein. 32 3.7
>BC072016-1|AAH72016.1| 466|Homo sapiens citrate synthase protein.
Length = 466
Score = 738 bits (1824), Expect = 0.0
Identities = 342/463 (73%), Positives = 393/463 (84%), Gaps = 2/463 (0%)
Query: 1 MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 60
MAL + L +C + R SA TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1 MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58
Query: 61 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEG 120
VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPEG
Sbjct: 59 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEG 118
Query: 121 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 180
LFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNSE
Sbjct: 119 LFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE 178
Query: 181 SKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSA 240
S FA+AY++G+ ++KYWE +YED+M+LIAKLP +AA IYRN+YR+G GIGAID N DWS
Sbjct: 179 SNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSH 238
Query: 241 NYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAG 300
N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLAG
Sbjct: 239 NFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAG 298
Query: 301 PLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYT 360
PLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYT
Sbjct: 299 PLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYT 358
Query: 361 CQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMN 420
CQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMN
Sbjct: 359 CQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMN 418
Query: 421 YYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
YYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 419 YYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 461
>BC010106-1|AAH10106.1| 466|Homo sapiens CS protein protein.
Length = 466
Score = 738 bits (1824), Expect = 0.0
Identities = 342/463 (73%), Positives = 393/463 (84%), Gaps = 2/463 (0%)
Query: 1 MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 60
MAL + L +C + R SA TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1 MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58
Query: 61 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEG 120
VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPEG
Sbjct: 59 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEG 118
Query: 121 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 180
LFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNSE
Sbjct: 119 LFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE 178
Query: 181 SKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSA 240
S FA+AY++G+ ++KYWE +YED+M+LIAKLP +AA IYRN+YR+G GIGAID N DWS
Sbjct: 179 SNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSH 238
Query: 241 NYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAG 300
N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLAG
Sbjct: 239 NFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAG 298
Query: 301 PLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYT 360
PLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYT
Sbjct: 299 PLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYT 358
Query: 361 CQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMN 420
CQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMN
Sbjct: 359 CQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMN 418
Query: 421 YYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
YYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 419 YYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 461
>AK074956-1|BAC11314.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ90475 fis, clone NT2RP3002721, highly similar to
Porcine citrate synthase mRNA. ).
Length = 466
Score = 738 bits (1824), Expect = 0.0
Identities = 342/463 (73%), Positives = 393/463 (84%), Gaps = 2/463 (0%)
Query: 1 MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 60
MAL + L +C + R SA TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1 MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58
Query: 61 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEG 120
VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPEG
Sbjct: 59 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEG 118
Query: 121 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 180
LFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNSE
Sbjct: 119 LFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE 178
Query: 181 SKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSA 240
S FA+AY++G+ ++KYWE +YED+M+LIAKLP +AA IYRN+YR+G GIGAID N DWS
Sbjct: 179 SNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSH 238
Query: 241 NYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAG 300
N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLAG
Sbjct: 239 NFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAG 298
Query: 301 PLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYT 360
PLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYT
Sbjct: 299 PLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYT 358
Query: 361 CQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMN 420
CQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMN
Sbjct: 359 CQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMN 418
Query: 421 YYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
YYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 419 YYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 461
>AF053631-1|AAQ13428.1| 466|Homo sapiens citrate synthase protein.
Length = 466
Score = 736 bits (1820), Expect = 0.0
Identities = 341/463 (73%), Positives = 392/463 (84%), Gaps = 2/463 (0%)
Query: 1 MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 60
MAL + L +C + R SA TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1 MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58
Query: 61 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEG 120
VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPEG
Sbjct: 59 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEG 118
Query: 121 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 180
LFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNSE
Sbjct: 119 LFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE 178
Query: 181 SKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSA 240
S FA+AY++G+ ++KYWE +YED+M+LIAKLP +AA IYRN+YR+G GIGAID N DWS
Sbjct: 179 SNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSH 238
Query: 241 NYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAG 300
N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSA SDPYLSFAA +NGLAG
Sbjct: 239 NFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSAFSDPYLSFAAAMNGLAG 298
Query: 301 PLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYT 360
PLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYT
Sbjct: 299 PLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYT 358
Query: 361 CQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMN 420
CQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMN
Sbjct: 359 CQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMN 418
Query: 421 YYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
YYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 419 YYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 461
>AF047042-1|AAC25560.1| 466|Homo sapiens citrate synthase protein.
Length = 466
Score = 733 bits (1813), Expect = 0.0
Identities = 341/463 (73%), Positives = 392/463 (84%), Gaps = 2/463 (0%)
Query: 1 MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 60
MAL + L +C + R SA TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1 MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58
Query: 61 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEG 120
VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPEG
Sbjct: 59 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEG 118
Query: 121 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 180
LFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNSE
Sbjct: 119 LFWLLVTGCIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE 178
Query: 181 SKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSA 240
S FA+AY+ G+ ++KYWE +YED+++LIAKLP +AA IYRN+Y +G GIGAID N DWS
Sbjct: 179 SNFAQAYARGISRTKYWELIYEDSVDLIAKLPCVAAKIYRNLYWEGSGIGAIDSNLDWSH 238
Query: 241 NYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAG 300
N+ NMLG+ D QFTELMRLYLTIHSDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLAG
Sbjct: 239 NFTNMLGYTDHQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAG 298
Query: 301 PLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYT 360
PLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYT
Sbjct: 299 PLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYT 358
Query: 361 CQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMN 420
CQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMN
Sbjct: 359 CQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMN 418
Query: 421 YYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
YYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 419 YYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 461
>BC000105-1|AAH00105.3| 409|Homo sapiens CS protein protein.
Length = 409
Score = 699 bits (1727), Expect = 0.0
Identities = 318/404 (78%), Positives = 361/404 (89%)
Query: 60 TKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 119
T VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPE
Sbjct: 1 TVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPE 60
Query: 120 GLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNS 179
GLFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P LHPMSQ SAAVTALNS
Sbjct: 61 GLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNS 120
Query: 180 ESKFAKAYSEGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWS 239
ES FA+AY++G+ ++KYWE +YED+M+LIAKLP +AA IYRN+YR+G GIGAID N DWS
Sbjct: 121 ESNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWS 180
Query: 240 ANYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLA 299
N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLA
Sbjct: 181 HNFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLA 240
Query: 300 GPLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRY 359
GPLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VVPGYGHAVLRKTDPRY
Sbjct: 241 GPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRY 300
Query: 360 TCQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEM 419
TCQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EM
Sbjct: 301 TCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEM 360
Query: 420 NYYTVMFGVSRALGVLAQLIWSRALGLPIERPKSLSTEMLMKQV 463
NYYTV+FGVSRALGVLAQLIWSRALG P+ERPKS+STE LMK V
Sbjct: 361 NYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFV 404
>BT007414-1|AAP36082.1| 264|Homo sapiens citrate synthase protein.
Length = 264
Score = 455 bits (1122), Expect = e-127
Identities = 206/259 (79%), Positives = 234/259 (90%)
Query: 205 MNLIAKLPVIAATIYRNVYRDGKGIGAIDDNKDWSANYCNMLGFDDPQFTELMRLYLTIH 264
M+LIAKLP +AA IYRN+YR+G GIGAID N DWS N+ NMLG+ D QFTEL RLYLTIH
Sbjct: 1 MDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELTRLYLTIH 60
Query: 265 SDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLEKLRKQVGDN 324
SDHEGGNVSAHT+HLVGSALSDPYLSFAA +NGLAGPLHGLANQEVLVWL +L+K+VG +
Sbjct: 61 SDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKD 120
Query: 325 FTEEQLKEFIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPLFKLVAAVYK 384
++E+L+++IW TL SG+VVPGYGHAVLRKTDPRYTCQREFALKHLPNDP+FKLVA +YK
Sbjct: 121 VSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYK 180
Query: 385 VVPPILTELGKVKNPWPNVDSHSGVLLQYYGLKEMNYYTVMFGVSRALGVLAQLIWSRAL 444
+VP +L E GK KNPWPNVD+HSGVLLQYYG+ EMNYYTV+FGVSRALGVLAQLIWSRAL
Sbjct: 181 IVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 240
Query: 445 GLPIERPKSLSTEMLMKQV 463
G P+ERPKS+STE LMK V
Sbjct: 241 GFPLERPKSMSTEGLMKFV 259
>DQ403132-1|ABD77265.1| 224|Homo sapiens citrate synthase protein.
Length = 224
Score = 402 bits (990), Expect = e-111
Identities = 179/224 (79%), Positives = 203/224 (90%)
Query: 225 DGKGIGAIDDNKDWSANYCNMLGFDDPQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSAL 284
+G GIGAID N DWS N+ NMLG+ D QFTEL RLYLTIHSDHEGGNVSAHT+HLVGSAL
Sbjct: 1 EGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSAL 60
Query: 285 SDPYLSFAAGLNGLAGPLHGLANQEVLVWLEKLRKQVGDNFTEEQLKEFIWKTLKSGQVV 344
SDPYLSFAA +NGLAGPLHGLANQEVLVWL +L+K+VG + ++E+L+++IW TL SG+VV
Sbjct: 61 SDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVV 120
Query: 345 PGYGHAVLRKTDPRYTCQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVKNPWPNVD 404
PGYGHAVLRKTDPRYTCQREFALKHLPNDP+FKLVA +YK+VP +L E GK KNPWPNVD
Sbjct: 121 PGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVD 180
Query: 405 SHSGVLLQYYGLKEMNYYTVMFGVSRALGVLAQLIWSRALGLPI 448
+HSGVLLQYYG+ EMNYYTV+FGVSRALGVLAQLIWSRALG P+
Sbjct: 181 AHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPL 224
>U18197-1|AAB60340.1| 1101|Homo sapiens ATP:citrate lyase protein.
Length = 1101
Score = 37.9 bits (84), Expect = 0.075
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 12/139 (8%)
Query: 251 PQFT-ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQE 309
P+++ + + + L + +DH AH T + A D S +GL + G
Sbjct: 883 PKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGA---- 938
Query: 310 VLVWLEKLRKQVGDNFTEEQLK-EFIWKTLKSGQVVPGYGHAV--LRKTDPRYTCQREFA 366
L+ K F + EF+ K K G+++ G GH V + D R +++
Sbjct: 939 ----LDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYV 994
Query: 367 LKHLPNDPLFKLVAAVYKV 385
+H P PL V K+
Sbjct: 995 RQHFPATPLLDYALEVEKI 1013
>BC006195-1|AAH06195.1| 1101|Homo sapiens ATP citrate lyase protein.
Length = 1101
Score = 37.9 bits (84), Expect = 0.075
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 12/139 (8%)
Query: 251 PQFT-ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQE 309
P+++ + + + L + +DH AH T + A D S +GL + G
Sbjct: 883 PKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGA---- 938
Query: 310 VLVWLEKLRKQVGDNFTEEQLK-EFIWKTLKSGQVVPGYGHAV--LRKTDPRYTCQREFA 366
L+ K F + EF+ K K G+++ G GH V + D R +++
Sbjct: 939 ----LDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYV 994
Query: 367 LKHLPNDPLFKLVAAVYKV 385
+H P PL V K+
Sbjct: 995 RQHFPATPLLDYALEVEKI 1013
>AK095084-1|BAC04484.1| 701|Homo sapiens mRNA. protein.
Length = 701
Score = 37.9 bits (84), Expect = 0.075
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 12/139 (8%)
Query: 251 PQFT-ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQE 309
P+++ + + + L + +DH AH T + A D S +GL + G
Sbjct: 483 PKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGA---- 538
Query: 310 VLVWLEKLRKQVGDNFTEEQLK-EFIWKTLKSGQVVPGYGHAV--LRKTDPRYTCQREFA 366
L+ K F + EF+ K K G+++ G GH V + D R +++
Sbjct: 539 ----LDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYV 594
Query: 367 LKHLPNDPLFKLVAAVYKV 385
+H P PL V K+
Sbjct: 595 RQHFPATPLLDYALEVEKI 613
>AB210035-1|BAE06117.1| 1137|Homo sapiens ACLY variant protein
protein.
Length = 1137
Score = 37.9 bits (84), Expect = 0.075
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 12/139 (8%)
Query: 251 PQFT-ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQE 309
P+++ + + + L + +DH AH T + A D S +GL + G
Sbjct: 919 PKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGA---- 974
Query: 310 VLVWLEKLRKQVGDNFTEEQLK-EFIWKTLKSGQVVPGYGHAV--LRKTDPRYTCQREFA 366
L+ K F + EF+ K K G+++ G GH V + D R +++
Sbjct: 975 ----LDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYV 1030
Query: 367 LKHLPNDPLFKLVAAVYKV 385
+H P PL V K+
Sbjct: 1031 RQHFPATPLLDYALEVEKI 1049
>X64330-1|CAA45614.1| 1105|Homo sapiens ATP-citrate (pro-S-)-lyase
protein.
Length = 1105
Score = 35.1 bits (77), Expect = 0.53
Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 251 PQFT-ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQE 309
P+++ + + + L + +DH AH T + + S +GL + G
Sbjct: 887 PKYSCQFIEMCLMVTADHGPAVSGAHNTIICARTAVELVSSLTSGLLTIGDRFGGA---- 942
Query: 310 VLVWLEKLRKQVGDNFTEEQLK-EFIWKTLKSGQVVPGYGHAV--LRKTDPRYTCQREFA 366
L+ K F + EF+ K K G+++ G GH V + D R +++
Sbjct: 943 ----LDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYV 998
Query: 367 LKHLPNDPLFKLVAAVYKV 385
+H P PL V K+
Sbjct: 999 RQHFPATPLLDYALEVEKI 1017
>AK024452-1|BAB15742.1| 1051|Homo sapiens FLJ00044 protein protein.
Length = 1051
Score = 32.3 bits (70), Expect = 3.7
Identities = 19/65 (29%), Positives = 28/65 (43%)
Query: 338 LKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPLFKLVAAVYKVVPPILTELGKVK 397
L G G+G + R++ P +TC R LP+DP A+ + PIL
Sbjct: 584 LLEGGPFSGFGEVLFRESVPMHTCARYLFTALLPHDPDLAYRLALRAMRLPILETAFPAG 643
Query: 398 NPWPN 402
P P+
Sbjct: 644 EPHPS 648
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,465,037
Number of Sequences: 224733
Number of extensions: 3105009
Number of successful extensions: 8889
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 8872
Number of HSP's gapped (non-prelim): 18
length of query: 465
length of database: 73,234,838
effective HSP length: 93
effective length of query: 372
effective length of database: 52,334,669
effective search space: 19468496868
effective search space used: 19468496868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)
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