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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000671-TA|BGIBMGA000671-PA|undefined
         (283 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8JKI7 Cluster: Tetracyclin-resistance protein; n=1; He...   295   1e-78
UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...   264   2e-69
UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC...   238   1e-61
UniRef50_Q0E8E1 Cluster: CG32158-PC, isoform C; n=5; Endopterygo...   222   9e-57
UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE466...    96   8e-19
UniRef50_UPI0000D56A3C Cluster: PREDICTED: similar to CG15890-PA...    95   1e-18
UniRef50_UPI0000D56A21 Cluster: PREDICTED: similar to CG15890-PA...    95   1e-18
UniRef50_Q8MZE0 Cluster: AT09365p; n=1; Drosophila melanogaster|...    93   7e-18
UniRef50_UPI00015B5EEF Cluster: PREDICTED: similar to ENSANGP000...    93   1e-17
UniRef50_Q17KH2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ...    91   2e-17
UniRef50_Q961H2 Cluster: GH23453p; n=5; Sophophora|Rep: GH23453p...    84   3e-15
UniRef50_UPI0000588589 Cluster: PREDICTED: similar to MGC80576 p...    83   6e-15
UniRef50_Q17KH5 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ...    79   1e-13
UniRef50_UPI0000E460CC Cluster: PREDICTED: similar to MGC80576 p...    79   1e-13
UniRef50_UPI00015B420B Cluster: PREDICTED: similar to adenylate ...    77   7e-13
UniRef50_UPI0000F20440 Cluster: PREDICTED: hypothetical protein;...    75   2e-12
UniRef50_Q16VM5 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    75   3e-12
UniRef50_A7SHN9 Cluster: Predicted protein; n=2; Nematostella ve...    74   4e-12
UniRef50_Q17KH3 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    73   1e-11
UniRef50_UPI0000DB7E26 Cluster: PREDICTED: similar to CG30345-PA...    72   1e-11
UniRef50_UPI0000E48DE8 Cluster: PREDICTED: similar to MGC80576 p...    72   2e-11
UniRef50_UPI00015B420D Cluster: PREDICTED: similar to adenylate ...    71   3e-11
UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA...    70   8e-11
UniRef50_Q4SFY6 Cluster: Chromosome 7 SCAF14601, whole genome sh...    67   4e-10
UniRef50_A7S0P7 Cluster: Predicted protein; n=3; Nematostella ve...    66   1e-09
UniRef50_Q9VA14 Cluster: CG15553-PA; n=3; Sophophora|Rep: CG1555...    65   2e-09
UniRef50_Q17KH4 Cluster: Adenylate cyclase, putative; n=1; Aedes...    62   1e-08
UniRef50_A7S9D8 Cluster: Predicted protein; n=1; Nematostella ve...    60   8e-08
UniRef50_UPI0000584089 Cluster: PREDICTED: similar to MGC80576 p...    59   1e-07
UniRef50_A7RIK2 Cluster: Predicted protein; n=1; Nematostella ve...    58   2e-07
UniRef50_UPI000069FC22 Cluster: Thymic stromal cotransporter hom...    58   3e-07
UniRef50_Q4TCI9 Cluster: Chromosome undetermined SCAF6885, whole...    58   3e-07
UniRef50_UPI000065D141 Cluster: UPI000065D141 related cluster; n...    57   6e-07
UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella ve...    56   8e-07
UniRef50_Q6P9B3 Cluster: SLC46A3 protein; n=14; Amniota|Rep: SLC...    55   2e-06
UniRef50_UPI00005889BC Cluster: PREDICTED: similar to HCP1 prote...    55   2e-06
UniRef50_Q96NT5-2 Cluster: Isoform 2 of Q96NT5 ; n=3; Homo/Pan/G...    55   2e-06
UniRef50_Q96NT5 Cluster: Proton-coupled folate transporter; n=21...    55   2e-06
UniRef50_UPI0000588588 Cluster: PREDICTED: similar to MGC80576 p...    54   3e-06
UniRef50_A1Z7R6 Cluster: CG8046-PA, isoform A; n=5; Sophophora|R...    54   4e-06
UniRef50_A7STS4 Cluster: Predicted protein; n=1; Nematostella ve...    54   5e-06
UniRef50_UPI000054694C Cluster: PREDICTED: hypothetical protein;...    53   7e-06
UniRef50_Q9BY10 Cluster: Thymic stromal cotransporter homolog; n...    53   7e-06
UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1; B...    51   4e-05
UniRef50_UPI0000E46FBF Cluster: PREDICTED: hypothetical protein;...    50   7e-05
UniRef50_UPI0000588A26 Cluster: PREDICTED: hypothetical protein;...    50   7e-05
UniRef50_A7RHU0 Cluster: Predicted protein; n=1; Nematostella ve...    49   1e-04
UniRef50_P02981 Cluster: Tetracycline resistance protein, class ...    49   1e-04
UniRef50_UPI000023DD03 Cluster: hypothetical protein FG06142.1; ...    47   5e-04
UniRef50_A3IH26 Cluster: Multidrug resistance protein, putative;...    46   0.001
UniRef50_Q7K0G5 Cluster: SD10604p; n=2; Sophophora|Rep: SD10604p...    46   0.001
UniRef50_A6U8Y2 Cluster: Major facilitator superfamily MFS_1; n=...    45   0.002
UniRef50_Q6FJ82 Cluster: Similar to sp|P46996 Saccharomyces cere...    45   0.002
UniRef50_A3ZND9 Cluster: Multidrug resistance protein; n=1; Blas...    45   0.003
UniRef50_Q07282 Cluster: Tetracycline resistance protein, class ...    45   0.003
UniRef50_UPI0000E45FD3 Cluster: PREDICTED: similar to MGC80576 p...    44   0.003
UniRef50_UPI0000586F99 Cluster: PREDICTED: hypothetical protein;...    44   0.003
UniRef50_UPI0000D8EF0C Cluster: Thymic stromal cotransporter hom...    44   0.003
UniRef50_Q6CD09 Cluster: Similar to sp|P46996 Saccharomyces cere...    44   0.003
UniRef50_UPI0000549B24 Cluster: PREDICTED: similar to thymic str...    44   0.004
UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS) per...    44   0.006
UniRef50_Q6ZVG5 Cluster: CDNA FLJ42613 fis, clone BRACE3014005; ...    44   0.006
UniRef50_Q17E18 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R...    43   0.008
UniRef50_Q9UAZ6 Cluster: Putative uncharacterized protein Y4C6B....    43   0.010
UniRef50_A7SJM3 Cluster: Predicted protein; n=1; Nematostella ve...    43   0.010
UniRef50_Q2G331 Cluster: Major facilitator superfamily MFS_1; n=...    42   0.013
UniRef50_Q966P2 Cluster: Putative uncharacterized protein; n=4; ...    42   0.013
UniRef50_Q4SYZ4 Cluster: Chromosome 10 SCAF11883, whole genome s...    42   0.018
UniRef50_Q7Q1Q1 Cluster: ENSANGP00000016542; n=1; Anopheles gamb...    42   0.018
UniRef50_Q8VVJ1 Cluster: TetA protein; n=5; Actinomycetales|Rep:...    42   0.023
UniRef50_Q1D6T2 Cluster: Putative multidrug resistance protein; ...    42   0.023
UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=...    42   0.023
UniRef50_A3UGP9 Cluster: Probable transporter; n=1; Oceanicaulis...    42   0.023
UniRef50_Q8INF8 Cluster: CG31321-PB; n=3; Sophophora|Rep: CG3132...    42   0.023
UniRef50_A3I9G6 Cluster: Multidrug-efflux transporter; n=1; Baci...    41   0.031
UniRef50_Q9RX43 Cluster: Tetracycline-efflux transporter; n=2; D...    41   0.041
UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -...    41   0.041
UniRef50_Q0CD81 Cluster: Predicted protein; n=6; Trichocomaceae|...    41   0.041
UniRef50_A3LRY8 Cluster: Predicted transporter ADD1; n=2; Saccha...    41   0.041
UniRef50_Q8DGS3 Cluster: Tlr2241 protein; n=1; Synechococcus elo...    40   0.054
UniRef50_Q20236 Cluster: Putative uncharacterized protein; n=2; ...    40   0.054
UniRef50_A7F7Q8 Cluster: Putative uncharacterized protein; n=1; ...    40   0.054
UniRef50_A7EBM9 Cluster: Putative uncharacterized protein; n=1; ...    40   0.054
UniRef50_Q9I4K4 Cluster: Probable major facilitator superfamily ...    40   0.072
UniRef50_Q8F6D6 Cluster: Tetracycline resistance protein, class ...    40   0.072
UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1; P...    40   0.072
UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3; Proteoba...    40   0.072
UniRef50_Q0U5D5 Cluster: Putative uncharacterized protein; n=1; ...    40   0.072
UniRef50_Q21M22 Cluster: Major facilitator superfamily MFS_1; n=...    39   0.13 
UniRef50_Q192M5 Cluster: Major facilitator superfamily MFS_1; n=...    39   0.13 
UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1; P...    39   0.13 
UniRef50_Q0HZC0 Cluster: Major facilitator superfamily MFS_1; n=...    39   0.17 
UniRef50_Q0AX92 Cluster: Multidrug-efflux transporter; n=1; Synt...    39   0.17 
UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=...    39   0.17 
UniRef50_Q12IY6 Cluster: Major facilitator superfamily MFS_1; n=...    38   0.22 
UniRef50_Q04HD0 Cluster: Permease of the major facilitator super...    38   0.22 
UniRef50_Q6BW37 Cluster: Similar to CA5023|IPF7547 Candida albic...    38   0.22 
UniRef50_A7TGR1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.22 
UniRef50_A6SA36 Cluster: Putative uncharacterized protein; n=1; ...    38   0.22 
UniRef50_Q6KZX2 Cluster: Putative multidrug resistance protein; ...    38   0.22 
UniRef50_Q0W242 Cluster: Putative permease; n=1; uncultured meth...    38   0.22 
UniRef50_Q65F99 Cluster: Blt; n=2; Bacillus|Rep: Blt - Bacillus ...    38   0.29 
UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA - Ac...    38   0.29 
UniRef50_Q21E97 Cluster: Major facilitator superfamily MFS_1; n=...    38   0.29 
UniRef50_A1RW34 Cluster: Major facilitator superfamily MFS_1; n=...    38   0.29 
UniRef50_UPI00002053B2 Cluster: PREDICTED: hippocampus abundant ...    38   0.38 
UniRef50_Q93S11 Cluster: Putative integral membrane transport pr...    38   0.38 
UniRef50_Q5WGK5 Cluster: Major facilitator (MFS) superfamily mul...    38   0.38 
UniRef50_A4A657 Cluster: Major facilitator family transporter; n...    38   0.38 
UniRef50_Q0W1K3 Cluster: Putative permease; n=1; uncultured meth...    38   0.38 
UniRef50_UPI0000EBDD0E Cluster: PREDICTED: hypothetical protein ...    37   0.50 
UniRef50_Q89MY8 Cluster: Tetracycline resistance protein; n=7; B...    37   0.50 
UniRef50_A3XKG1 Cluster: Multidrug-efflux transporter; n=2; Flav...    37   0.50 
UniRef50_A5DS14 Cluster: Putative uncharacterized protein; n=1; ...    37   0.50 
UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1; ...    37   0.50 
UniRef50_Q01NN6 Cluster: Multi-sensor signal transduction histid...    37   0.67 
UniRef50_A3VN57 Cluster: Permease; n=1; Parvularcula bermudensis...    37   0.67 
UniRef50_A4S4A5 Cluster: Predicted protein; n=2; Ostreococcus|Re...    37   0.67 
UniRef50_Q4J8C3 Cluster: Conserved membrane protein; n=2; Sulfol...    37   0.67 
UniRef50_Q2SB41 Cluster: Putative uncharacterized protein; n=1; ...    36   0.88 
UniRef50_Q1ARX5 Cluster: Major facilitator superfamily MFS_1; n=...    36   0.88 
UniRef50_A7HKI1 Cluster: Major facilitator superfamily MFS_1; n=...    36   0.88 
UniRef50_Q97C83 Cluster: Multidrug resistance protein; n=3; Ther...    36   0.88 
UniRef50_Q4RG87 Cluster: Chromosome 12 SCAF15104, whole genome s...    36   1.2  
UniRef50_Q8DMH7 Cluster: Multidrug-efflux transporter; n=2; Cyan...    36   1.2  
UniRef50_Q2MDB3 Cluster: Tetracycline efllux protein; n=6; Prote...    36   1.2  
UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=...    36   1.2  
UniRef50_Q0RU88 Cluster: Putative membrane transport protein; n=...    36   1.2  
UniRef50_A6W364 Cluster: Major facilitator superfamily MFS_1 pre...    36   1.2  
UniRef50_A4RGD5 Cluster: Putative uncharacterized protein; n=2; ...    36   1.2  
UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS famil...    36   1.5  
UniRef50_A2U0E9 Cluster: Sugar transporter; n=5; Flavobacteria|R...    36   1.5  
UniRef50_A1FU26 Cluster: General substrate transporter; n=1; Ste...    36   1.5  
UniRef50_Q0DJA5 Cluster: Os05g0307100 protein; n=2; Oryza sativa...    36   1.5  
UniRef50_A2G4W0 Cluster: Nuclear division RFT1-like protein, put...    36   1.5  
UniRef50_A4YF51 Cluster: Major facilitator superfamily MFS_1 pre...    36   1.5  
UniRef50_Q88YJ0 Cluster: Multidrug transport protein; n=5; Lacto...    35   2.0  
UniRef50_Q0C4X1 Cluster: Tetracycline-efflux transporter; n=1; H...    35   2.0  
UniRef50_A5FYH1 Cluster: Major facilitator superfamily MFS_1 pre...    35   2.0  
UniRef50_A0YM33 Cluster: General substrate transporter; n=4; Cya...    35   2.0  
UniRef50_A7SUG3 Cluster: Predicted protein; n=1; Nematostella ve...    35   2.0  
UniRef50_Q4WVN5 Cluster: MFS multidrug transporter, putative; n=...    35   2.0  
UniRef50_Q2HC27 Cluster: Putative uncharacterized protein; n=1; ...    35   2.0  
UniRef50_A7EHS0 Cluster: Putative uncharacterized protein; n=1; ...    35   2.0  
UniRef50_UPI00015978DB Cluster: putative permease MDR type; n=1;...    35   2.7  
UniRef50_Q2ARG1 Cluster: General substrate transporter:Major fac...    35   2.7  
UniRef50_Q1QFP1 Cluster: Major facilitator superfamily MFS_1; n=...    35   2.7  
UniRef50_A6GIA5 Cluster: Transporter, major facilitator family p...    35   2.7  
UniRef50_A6F246 Cluster: Mg/Co/Ni transporter MgtE; n=1; Marinob...    35   2.7  
UniRef50_Q7S282 Cluster: Predicted protein; n=1; Neurospora cras...    35   2.7  
UniRef50_Q6CLW6 Cluster: Similarities with sp|P46996 Saccharomyc...    35   2.7  
UniRef50_A7D0E0 Cluster: Major facilitator superfamily MFS_1; n=...    35   2.7  
UniRef50_P46996 Cluster: Uncharacterized membrane protein YJL163...    35   2.7  
UniRef50_Q28RT4 Cluster: Major facilitator superfamily MFS_1; n=...    34   3.6  
UniRef50_Q1DG35 Cluster: Drug resistance transporter, EmrB/QacA ...    34   3.6  
UniRef50_A2SG94 Cluster: Tetracycline-efflux transporter; n=2; P...    34   3.6  
UniRef50_A1R2T1 Cluster: Putative major facilitator superfamily ...    34   3.6  
UniRef50_Q6BTW2 Cluster: Similar to tr|Q9HF77 Candida albicans F...    34   3.6  
UniRef50_Q3ZXW4 Cluster: Major facilitator family transporter; n...    34   4.7  
UniRef50_Q1IVW2 Cluster: Major facilitator superfamily MFS_1; n=...    34   4.7  
UniRef50_A7FUI5 Cluster: Major facilitator family protein; n=4; ...    34   4.7  
UniRef50_A6G4P7 Cluster: Antibiotic resistance protein; n=1; Ple...    34   4.7  
UniRef50_A3I0S1 Cluster: Multidrug transporter, putative; n=1; A...    34   4.7  
UniRef50_A0UKQ2 Cluster: Major facilitator superfamily MFS_1; n=...    34   4.7  
UniRef50_Q86EF4 Cluster: Clone ZZD455 mRNA sequence; n=3; Schist...    34   4.7  
UniRef50_A1RTX0 Cluster: Major facilitator superfamily MFS_1; n=...    34   4.7  
UniRef50_Q83C69 Cluster: Uncharacterized protein CBU_1260 precur...    34   4.7  
UniRef50_UPI0000E4618C Cluster: PREDICTED: hypothetical protein,...    33   6.2  
UniRef50_UPI0000DAE55E Cluster: hypothetical protein Rgryl_01000...    33   6.2  
UniRef50_UPI0000499E89 Cluster: major facilitator superfamily pr...    33   6.2  
UniRef50_Q97L04 Cluster: Permease, probably tetracycline resista...    33   6.2  
UniRef50_Q8DIK2 Cluster: Tlr1583 protein; n=8; Cyanobacteria|Rep...    33   6.2  
UniRef50_Q62FE5 Cluster: Major facilitator family transporter; n...    33   6.2  
UniRef50_Q0SDT0 Cluster: Metabolite transporter, MFS superfamily...    33   6.2  
UniRef50_A6E8D0 Cluster: Kynureninase; n=1; Pedobacter sp. BAL39...    33   6.2  
UniRef50_A4X8R4 Cluster: Drug resistance transporter, EmrB/QacA ...    33   6.2  
UniRef50_A3WGM5 Cluster: Transporter, NRAMP family protein; n=1;...    33   6.2  
UniRef50_A3UHT7 Cluster: Major facilitator family transporter; n...    33   6.2  
UniRef50_A0YH94 Cluster: Putative transmembrane efflux protein; ...    33   6.2  
UniRef50_A0ISG2 Cluster: Major facilitator superfamily MFS_1; n=...    33   6.2  
UniRef50_O28265 Cluster: Sugar transporter, putative; n=1; Archa...    33   6.2  
UniRef50_Q9RN46 Cluster: 12-TMS multidrug efflux protein homolog...    33   8.2  
UniRef50_Q75TC8 Cluster: Multidrug-efflux transporter; n=3; Geob...    33   8.2  
UniRef50_Q53903 Cluster: ActVA 1 protein; n=1; Streptomyces coel...    33   8.2  
UniRef50_Q3B5W4 Cluster: VCBS; n=2; cellular organisms|Rep: VCBS...    33   8.2  
UniRef50_Q0SUN9 Cluster: Putative uncharacterized protein; n=1; ...    33   8.2  
UniRef50_Q0LMR4 Cluster: Major facilitator superfamily MFS_1 pre...    33   8.2  
UniRef50_A4WAA4 Cluster: General substrate transporter; n=2; Ent...    33   8.2  
UniRef50_A3EQV7 Cluster: Permease of the major facilitator super...    33   8.2  
UniRef50_A0K0Q4 Cluster: Major facilitator superfamily MFS_1; n=...    33   8.2  
UniRef50_A0GXY1 Cluster: Major facilitator superfamily MFS_1; n=...    33   8.2  
UniRef50_Q6ET95 Cluster: Tetracycline transporter protein-like; ...    33   8.2  
UniRef50_Q7SFA1 Cluster: Predicted protein; n=1; Neurospora cras...    33   8.2  
UniRef50_A4R5W6 Cluster: Putative uncharacterized protein; n=3; ...    33   8.2  
UniRef50_A2R6P9 Cluster: Contig An16c0020, complete genome; n=1;...    33   8.2  
UniRef50_A1DAV5 Cluster: MFS transporter, putative; n=10; Pezizo...    33   8.2  
UniRef50_A1CV39 Cluster: MFS transporter, putative; n=1; Neosart...    33   8.2  
UniRef50_Q9HLK4 Cluster: Self-defense gene tcr3 related protein;...    33   8.2  

>UniRef50_Q8JKI7 Cluster: Tetracyclin-resistance protein; n=1;
           Heliothis zea virus 1|Rep: Tetracyclin-resistance
           protein - Heliothis zea virus 1
          Length = 512

 Score =  295 bits (723), Expect = 1e-78
 Identities = 130/180 (72%), Positives = 155/180 (86%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTV 64
           +++TVEP MF YMMA+M T VIEQ FYV+Q C +NHGYS E+C+NIS++ DIN  VQ TV
Sbjct: 6   QWLTVEPPMFLYMMAFMTTTVIEQAFYVYQACTVNHGYSPEVCHNISQYDDINNRVQQTV 65

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVE 124
           STFHQWNG+ASHVVP  LAFFLGSYSD+RGRKIVL+ GL+GKL+FS M+TVN++  WPVE
Sbjct: 66  STFHQWNGVASHVVPFILAFFLGSYSDRRGRKIVLVCGLVGKLFFSAMLTVNSLKSWPVE 125

Query: 125 YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHI 184
           Y+IYTA+ PSALTGADLAIFA CFAYIADVS+V+NRTLRVGILD  YLST+P G+AI  +
Sbjct: 126 YIIYTASFPSALTGADLAIFAACFAYIADVSTVENRTLRVGILDAVYLSTMPTGVAIGSV 185



 Score =  137 bits (332), Expect = 3e-31
 Identities = 61/100 (61%), Positives = 78/100 (78%)

Query: 180 AIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVM 239
           A+AHI GHLVYAH  +  + Y+GAT AALGP VAPL+RS+ SK+LP  ERGVAYAFLSVM
Sbjct: 336 AVAHICGHLVYAHAKIANLWYLGATLAALGPCVAPLLRSMASKVLPASERGVAYAFLSVM 395

Query: 240 ENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVF 279
           ENAV +FA++ Y+Q+Y  T+ T++ N+ FY T+ T V VF
Sbjct: 396 ENAVGMFAAVAYSQLYKNTLDTQFSNATFYLTVGTLVAVF 435


>UniRef50_Q17ME2 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 492

 Score =  264 bits (646), Expect = 2e-69
 Identities = 122/217 (56%), Positives = 161/217 (74%), Gaps = 6/217 (2%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQV 62
           WY  ITVEP+MF YMMA+M+T+VIEQ F++++ C +NHGYS +IC NI  + DI KEVQ+
Sbjct: 16  WYHKITVEPSMFLYMMAFMLTSVIEQVFFLYKACTVNHGYSHDICINIESYQDIKKEVQI 75

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT-MNDW 121
           T S FH WN IA +VVP+ LA FLG++SD+RGRK+ L+ GL+GK  +S+MI VNT M  W
Sbjct: 76  TTSNFHMWNNIAMYVVPIVLALFLGAWSDRRGRKLPLILGLIGKFVYSVMIVVNTRMETW 135

Query: 122 PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           PVEY+IYTA +PS LTGAD+AIFA CFAYI+DV++V +RT R+ ILD TYLST+P+G+AI
Sbjct: 136 PVEYIIYTATIPSVLTGADIAIFASCFAYISDVTTVADRTFRITILDATYLSTMPIGVAI 195

Query: 182 AHITGHLVYAHTTVG-KMMYVGATAAALGPIVAPLIR 217
               G L+Y  T     +M+    +  L  I+  +IR
Sbjct: 196 ----GSLIYNRTARSFTIMFAINASLLLLSIIYSIIR 228



 Score =  102 bits (245), Expect = 9e-21
 Identities = 46/101 (45%), Positives = 71/101 (70%), Gaps = 1/101 (0%)

Query: 180 AIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVM 239
           A AH     VY    V  ++YVGA+ ++LGP+VAP++RS+ SK++P  ERG+ ++FLSV 
Sbjct: 350 ATAHAMARFVYIFAEVDWLLYVGASISSLGPVVAPVLRSMISKMVPTTERGIIFSFLSVF 409

Query: 240 ENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFL 280
           +NAV + + ++YTQIYNA+I + +  + F  T+ TQ +VFL
Sbjct: 410 DNAVPLVSGVLYTQIYNASINS-FPQAFFLLTMGTQAVVFL 449


>UniRef50_UPI0000D56BF4 Cluster: PREDICTED: similar to CG32158-PC,
           isoform C; n=2; Endopterygota|Rep: PREDICTED: similar to
           CG32158-PC, isoform C - Tribolium castaneum
          Length = 478

 Score =  238 bits (583), Expect = 1e-61
 Identities = 103/183 (56%), Positives = 143/183 (78%), Gaps = 1/183 (0%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQV 62
           + K ITVEPTM  YMMA+M T+V+EQ F+V + C +NHG +  IC N++++ ++NKEVQV
Sbjct: 17  YLKLITVEPTMVLYMMAFMTTSVVEQAFFVNKACRVNHGLNASICDNLTEYEELNKEVQV 76

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVN-TMNDW 121
           TVS FH +N +A HVVP+ LA F+G++SDKRGRK+ LL GL GKLY+S+M+ VN T + W
Sbjct: 77  TVSDFHLYNDVAGHVVPIILALFMGAWSDKRGRKLPLLIGLTGKLYYSVMVVVNATQDTW 136

Query: 122 PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           PVEY++YTA LP A TGAD+AIFA  F Y+ D+S+ ++RT+RV +L+V YL+T+P GIA+
Sbjct: 137 PVEYIVYTATLPMAFTGADVAIFAAAFTYLVDISTQESRTMRVTLLEVCYLATMPTGIAL 196

Query: 182 AHI 184
             +
Sbjct: 197 GKV 199



 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 46/104 (44%), Positives = 70/104 (67%), Gaps = 1/104 (0%)

Query: 180 AIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVM 239
           A+AH  G + +A      M Y+G   AA+GPIVAP+IRS+ SKL+   E+G   A L+V 
Sbjct: 350 ALAHSVGRIFFATADESWMFYLGGVFAAIGPIVAPVIRSMVSKLVANSEKGKTLAVLAVA 409

Query: 240 ENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
           +NA+ + +  +Y+++YNATI T + N+IFY T++TQ+ VF+  L
Sbjct: 410 DNAIPLISGTMYSKVYNATIHT-HPNAIFYLTMATQMTVFVLIL 452


>UniRef50_Q0E8E1 Cluster: CG32158-PC, isoform C; n=5;
           Endopterygota|Rep: CG32158-PC, isoform C - Drosophila
           melanogaster (Fruit fly)
          Length = 533

 Score =  222 bits (542), Expect = 9e-57
 Identities = 107/212 (50%), Positives = 150/212 (70%), Gaps = 8/212 (3%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISK--HADINKEVQV 62
           K  +VEPTMF YM A+MIT+V+EQ F+++++C +N  ++ EIC N++K  + +   +  +
Sbjct: 55  KSTSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAML 114

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT-MNDW 121
           T + F QW  I++HV P+ LA FLGS+SD+RGRK+ LL GL+GK ++S MI VN  M  W
Sbjct: 115 TNAWFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTW 174

Query: 122 PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           PV+ +IY+A LPSALTGAD+AIFA CFAYI+D+SS++ RT+RV ILDV YLS +PMG+A+
Sbjct: 175 PVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVAL 234

Query: 182 AHITGHLVY--AHTTVGKMMYVGATAAALGPI 211
                HL Y   + +   M  V A+  AL  I
Sbjct: 235 G---SHLFYNVFNQSYADMFTVNASLLALAII 263



 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 42/102 (41%), Positives = 63/102 (61%)

Query: 182 AHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMEN 241
           AH    L +   T   ++Y GA   +LGPIV P+IR++TSK++P  ERG  +A LSV +N
Sbjct: 392 AHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDN 451

Query: 242 AVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
           AV   + + Y+Q+Y  T  T +  ++F  TI+TQ+ VF+  L
Sbjct: 452 AVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMIL 493


>UniRef50_Q6NPA2 Cluster: RE46682p; n=6; Endopterygota|Rep: RE46682p
           - Drosophila melanogaster (Fruit fly)
          Length = 599

 Score = 96.3 bits (229), Expect = 8e-19
 Identities = 55/186 (29%), Positives = 100/186 (53%), Gaps = 9/186 (4%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADIN-----KEVQ 61
           +TVEP +  Y+M  +++N+  Q   + + C +N  Y  E+C  +++    N     + VQ
Sbjct: 70  VTVEPILAAYIMPSVLSNLATQNLNLEKACRVNMAYGDEVCDALTRRQTANYTLEEETVQ 129

Query: 62  VTVSTFHQWNGIASHVVPLFLAFFLGSYSDK-RGRKIVLLAGLLGKLY--FSIMITVNTM 118
             V+    W  +   + P  L  F GS+SD+ R RK  +L  ++G+      +M+ V   
Sbjct: 130 QMVARMAAWKTVIQSLFPCLLILFWGSWSDRHRRRKPCILIPVVGEFLGVVGLMLCVY-F 188

Query: 119 NDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMG 178
              P+E    T A+  +L+G    +  G F+YIAD+++ ++RTLR+GIL+V +   +P+G
Sbjct: 189 EQAPMEAAALTEAIFPSLSGGWFTMLMGVFSYIADITTEEDRTLRIGILNVCFSVGVPIG 248

Query: 179 IAIAHI 184
           +A + +
Sbjct: 249 MAFSGV 254



 Score = 41.5 bits (93), Expect = 0.023
 Identities = 23/76 (30%), Positives = 36/76 (47%)

Query: 184 ITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAV 243
           I    VYA  T+ + MY+G             +RSI +KL+  DE G   +   V E  +
Sbjct: 406 ILSSFVYAFATLPRHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALM 465

Query: 244 AIFASIVYTQIYNATI 259
            +  + +YT +Y AT+
Sbjct: 466 PMVFAPMYTTLYAATL 481


>UniRef50_UPI0000D56A3C Cluster: PREDICTED: similar to CG15890-PA;
           n=3; Coelomata|Rep: PREDICTED: similar to CG15890-PA -
           Tribolium castaneum
          Length = 666

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 54/190 (28%), Positives = 105/190 (55%), Gaps = 9/190 (4%)

Query: 4   YKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEIC-----YNISKHADINK 58
           +  ITVEP +  +++  ++ N+  Q   + + C +N   S ++C      ++S++   ++
Sbjct: 19  FNNITVEPILVCFVLPCVMANLATQNLNMDKACRVNLHLSEQVCDGLALRDVSRYNQSDE 78

Query: 59  -EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDK-RGRKIVLLAGLLGKLYFSIMITVN 116
             VQ  V+T + W  +    VP  L  FLGS+SD+ + RK   L  ++G++   + + + 
Sbjct: 79  VAVQKLVATMNAWKNVIQSFVPSLLLLFLGSWSDRHKRRKPCFLGPIIGEMVTCMGLLLC 138

Query: 117 TMNDW--PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
           T   +  PVEY ++  A+P +LTG   A+F   F+Y+  ++SV+ RTLR+G +++    +
Sbjct: 139 TFFYYQLPVEYNVFFEAVPPSLTGGWFAMFMAVFSYVGGITSVQTRTLRIGAVNIFVNIS 198

Query: 175 LPMGIAIAHI 184
             +G A++ I
Sbjct: 199 FTVGNALSGI 208



 Score = 44.8 bits (101), Expect = 0.003
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 182 AHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMEN 241
           + I   +VYA        YVGA            +RSI SKL+PPDE G   +   + E 
Sbjct: 357 SRIVASMVYAFAPNAFTFYVGALIEIFNGTTFIAMRSIISKLVPPDELGKINSLFGLSEA 416

Query: 242 AVAIFASIVYTQIYNATIGTEYINSIFY 269
            V I    +Y+ +Y  TI   Y+   F+
Sbjct: 417 MVPIIYGPLYSIVYKHTI--NYLPGTFF 442


>UniRef50_UPI0000D56A21 Cluster: PREDICTED: similar to CG15890-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG15890-PA - Tribolium castaneum
          Length = 505

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 62/187 (33%), Positives = 97/187 (51%), Gaps = 10/187 (5%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNI-----SKHADINKEVQ 61
           ITVEP +  Y++A +I           + C  N   +  IC  I     + +++ N+++Q
Sbjct: 36  ITVEPLIAAYLLASIICGPALYNLEFEKGCRSNLQLNDSICDAILSGEATNYSEENEKIQ 95

Query: 62  VTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRG-RKIVLLAGLLGKLYF--SIMITVNTM 118
           + +   H W      V+PL L  FLGSYSD+   RK  LL  +LG+ +     ++ V  M
Sbjct: 96  ILIGDMHSWQIPLQSVMPLILVLFLGSYSDRHKLRKPFLLIPVLGEFFAVAGCILCVVFM 155

Query: 119 NDWPV-EYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPM 177
            +WP+    I    +PS   G  + + A  FAYIADVS+V+ RTLRVG++ +      P+
Sbjct: 156 KEWPLASQGIAQTVIPSFFGGQTMIVMA-VFAYIADVSTVEMRTLRVGVVQIVLNVCTPV 214

Query: 178 GIAIAHI 184
           G A++ I
Sbjct: 215 GQAVSGI 221


>UniRef50_Q8MZE0 Cluster: AT09365p; n=1; Drosophila
           melanogaster|Rep: AT09365p - Drosophila melanogaster
           (Fruit fly)
          Length = 532

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 42/102 (41%), Positives = 63/102 (61%)

Query: 182 AHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMEN 241
           AH    L +   T   ++Y GA   +LGPIV P+IR++TSK++P  ERG  +A LSV +N
Sbjct: 391 AHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDN 450

Query: 242 AVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
           AV   + + Y+Q+Y  T  T +  ++F  TI+TQ+ VF+  L
Sbjct: 451 AVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMIL 492


>UniRef50_UPI00015B5EEF Cluster: PREDICTED: similar to
           ENSANGP00000027535; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000027535 - Nasonia
           vitripennis
          Length = 593

 Score = 92.7 bits (220), Expect = 1e-17
 Identities = 56/186 (30%), Positives = 98/186 (52%), Gaps = 8/186 (4%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVT--- 63
           ITVEP + FY+M  ++ ++  Q   + + C +N GYS  IC  ++       E++ T   
Sbjct: 70  ITVEPMVAFYIMPSVLASLATQNLNLEKACKVNLGYSDAICAALAARNTSGLELEETAVQ 129

Query: 64  --VSTFHQWNGIASHVVPLFLAFFLGSYSDKRG-RKIVLLAGLLGKLYFSIMIT--VNTM 118
             V++   W        P  L  F+G++SD+ G RK  ++  ++G+   SI +   V   
Sbjct: 130 QLVASMQTWKTALQSFFPSILIVFMGAWSDRNGLRKPCMMLPIVGEFLTSISLIACVYWF 189

Query: 119 NDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMG 178
            + P+E      AL  ALTG    +  G F+YI D++SV++RT+RVG ++      +P+G
Sbjct: 190 YELPMEAAGVFEALWPALTGGWFTMIMGTFSYIGDITSVESRTVRVGAVNSFLSLGVPVG 249

Query: 179 IAIAHI 184
           +A++ +
Sbjct: 250 MALSGV 255



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 28/79 (35%), Positives = 41/79 (51%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           ++ I    VYA +T   MMY+      +      ++RSITSKL+PPDE G   +   V E
Sbjct: 417 VSKILASFVYAFSTTDWMMYIAPLVEIINGTSFIVMRSITSKLVPPDELGKVNSLFGVCE 476

Query: 241 NAVAIFASIVYTQIYNATI 259
             V +    +Y+ IY AT+
Sbjct: 477 AIVPLVYGPMYSSIYGATV 495


>UniRef50_Q17KH2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 483

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 48/186 (25%), Positives = 93/186 (50%), Gaps = 10/186 (5%)

Query: 4   YKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKH-------ADI 56
           Y+Y  +EP +     A+ +++ +     V+Q C +   ++  +C  +           ++
Sbjct: 26  YRYFILEPAILLLFYAWNVSSAVFTNQVVYQACTVTFQHNETLCAQLGTENETQPEIEEL 85

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVN 116
            +EVQ   +T      +   ++P   + F+G +SDK GRK VL++  +G  +   ++ V 
Sbjct: 86  EREVQPYAATILMAKSLIESIIPALCSMFIGPWSDKYGRKPVLMSTFIGSFFTYTLVAVI 145

Query: 117 TM--NDWPVEYVIYTAA-LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLS 173
               + + V+   Y  A +P+AL+G + A+  G F YI DV+S +NR +++G+L+     
Sbjct: 146 CFLSSQYEVDPWYYILAYIPAALSGGNCALITGVFCYITDVTSEQNRAVKMGVLEAAIFG 205

Query: 174 TLPMGI 179
            L  GI
Sbjct: 206 GLLFGI 211



 Score = 36.7 bits (81), Expect = 0.67
 Identities = 14/61 (22%), Positives = 33/61 (54%)

Query: 199 MYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNAT 258
           +Y+G   + +  I  P+ R++ S   PP + G  ++  + +E+   + ++ +YT +Y  T
Sbjct: 382 LYLGIGVSMMKGIAGPMGRAVISNTAPPSDIGKIFSLTTSIESLTPLASAPIYTYVYKQT 441

Query: 259 I 259
           +
Sbjct: 442 M 442


>UniRef50_Q961H2 Cluster: GH23453p; n=5; Sophophora|Rep: GH23453p -
           Drosophila melanogaster (Fruit fly)
          Length = 507

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 54/200 (27%), Positives = 97/200 (48%), Gaps = 14/200 (7%)

Query: 4   YKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEIC---YNISKHADINKEV 60
           Y++  +EP +F    A  +   + Q   ++QTC     ++   C     I + +D +KEV
Sbjct: 49  YRWFILEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEV 108

Query: 61  QVTVSTFH----QWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKL---YFSIMI 113
           +V V T+         +   ++P F + FLG +SDK GR+ +LL    G L      I+I
Sbjct: 109 EVIVQTYSANIMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVI 168

Query: 114 TVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLS 173
           T  T +     +    +++PS ++G   A+  G + YI+DV+  + + LR+    V   +
Sbjct: 169 TYITRSTNISPWWFLLSSVPSVVSGGTCALITGIYCYISDVAKERKKALRM----VLNEA 224

Query: 174 TLPMGIAIAHITGHLVYAHT 193
           +L  GI + ++    +YA T
Sbjct: 225 SLCAGIMVGNVASGYIYAAT 244



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 28/120 (23%), Positives = 57/120 (47%), Gaps = 1/120 (0%)

Query: 140 DLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMM 199
           D ++F      I  V S+    +   +L ++ ++   + +A   +    V A     + +
Sbjct: 346 DFSLFNASRIVIQIVGSIVGMLVLRRVLKMSIVTMAMLSLACC-VLESTVRATAVYWQEL 404

Query: 200 YVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATI 259
           Y+G T   +  ++ P+ R+I S + P  E G  +A  + ME+   + A+ +YT +Y AT+
Sbjct: 405 YLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSPLGAAPLYTTVYKATL 464


>UniRef50_UPI0000588589 Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 514

 Score = 83.4 bits (197), Expect = 6e-15
 Identities = 51/178 (28%), Positives = 85/178 (47%), Gaps = 4/178 (2%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTV 64
           K +TVEP +F +M  + +   I Q   + + C +   Y   +C N +  A I  EV+   
Sbjct: 10  KAVTVEPVLFLFMFGFFLQGPILQLLIIQKVCRLT--YDGSVCSNKTAFAKIEDEVESDS 67

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMN-DWPV 123
           S +  +  +AS V    +A  LG  SDK GRKI++    +G    +I   +N+   DWPV
Sbjct: 68  SRWILFFNLASMVPGAIMATILGPLSDKVGRKIIMTLPSIGAAVGAINFILNSFYIDWPV 127

Query: 124 EYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           E  +  + +   +TG     F    +YI D++   +R  R+G+L+        +G+ I
Sbjct: 128 E-TLLLSGVAMGITGNLGTFFVSVVSYITDITDPSSRMKRLGLLEAMVYIGGTLGLVI 184


>UniRef50_Q17KH5 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 514

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 14/212 (6%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADIN--KE----V 60
           +++EP        + ++ ++     + QTC    GY+  +C  +  +++    KE    V
Sbjct: 51  LSLEPVAVALCFGWSMSGIVLSNQIIHQTCWYM-GYNASLCATLGANSNATGAKELEALV 109

Query: 61  QVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKL--YFSIMITVNTM 118
           Q TV+     + I + V+P     FLG +SDK GRK V++   +G +  Y +  I     
Sbjct: 110 QPTVAKITMTSSIITSVIPALCGLFLGPWSDKFGRKPVMIIPCVGYIVSYVTKAIICQAS 169

Query: 119 NDWPVEYVIYTAA-LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPM 177
           +  P+   +Y  A +P+A++G     +AG F+Y+ADVS+  NR +R+G+L  + L     
Sbjct: 170 SLLPLNPWLYVYADIPAAISGGTTVFYAGMFSYLADVSNEGNRAVRMGMLQGSSLG---- 225

Query: 178 GIAIAHITGHLVYAHTTVGKMMYVGATAAALG 209
           G  +  ++   +   T    +  + A+    G
Sbjct: 226 GAFVGMLSSSFILQLTNTATVFMISASMMLFG 257


>UniRef50_UPI0000E460CC Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 382

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 55/183 (30%), Positives = 92/183 (50%), Gaps = 10/183 (5%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFY---VFQTCHINH-GYSTEICYNI---SKHAD 55
           W   + VEP    +M+AY +   I   +    + +  +      +T +  ++   S+  D
Sbjct: 20  WRSRLIVEPLTVTFMLAYGLLVTIRVEYLNKRLSEEANFTQPSTNTSVVCSLNTSSEEYD 79

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
              EVQ   S +  +  +A  +  LF A FLG+ SD RGR+I +L  ++G   +SI+  +
Sbjct: 80  RYLEVQTQTSYWTLYLAVAQSIPALFSANFLGALSDARGRRIAMLFPIVGFAIYSIVYAL 139

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
                W + Y+++  A+P  L G  L + A  FAY+AD ++ K RT R+ IL+   L+TL
Sbjct: 140 VAQFHWSL-YILFAGAIPLGLCGDFLTLVACSFAYVADTTTSKQRTYRMVILEC--LTTL 196

Query: 176 PMG 178
             G
Sbjct: 197 GAG 199


>UniRef50_UPI00015B420B Cluster: PREDICTED: similar to adenylate
           cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to adenylate cyclase - Nasonia vitripennis
          Length = 461

 Score = 76.6 bits (180), Expect = 7e-13
 Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 12/198 (6%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHA------DI 56
           W ++  +EP  F  + A+ +++ +    +V+QTC      +   C  +  ++      DI
Sbjct: 8   WRRFAAMEPLAFALLFAFSVSDNVMSDLFVYQTCKSTAALNISDCDILHTNSSSDRAKDI 67

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKL--YFSIMIT 114
            K VQ   +    +      + P  ++ FLG +SDK GRK +L+    G L  YFS+ I 
Sbjct: 68  EKLVQPHTTIVLIFKSCIDTIFPTIMSLFLGPWSDKNGRKPLLVIPFTGFLLSYFSLAIL 127

Query: 115 VNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
            N  N  P  Y    +++PS+L G   AI    F YI D++  +NR   +  +    L  
Sbjct: 128 SN-FNANP--YWFLLSSIPSSLLGGFPAILLTFFCYITDITDNQNRAWHLACIQTMILIG 184

Query: 175 LPMGIAIA-HITGHLVYA 191
           + +G+ +   +  H  YA
Sbjct: 185 MLLGLFVGPAVFSHFGYA 202



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 199 MYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNAT 258
           MY  A+         P+IRSI SK +PP + G  ++ ++ ME  +    + +Y  +Y  T
Sbjct: 356 MYFSASIGMFSSSATPVIRSIVSKSVPPQDLGKTFSLITTMEMTIPFATTPLYIYVYTHT 415

Query: 259 IGTEYINSIFYFTISTQVIVFLSAL 283
           +   Y   +++ + +  V + + A+
Sbjct: 416 L-KYYPCPVWFLSAALPVFIIILAV 439


>UniRef50_UPI0000F20440 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 448

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 8/168 (4%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTV 64
           + +TVEP +F YM +  I     Q   + + C  +   +  IC +   H +  + VQ T 
Sbjct: 10  RIVTVEPVIFLYMSSSFIVTPAIQQMIITKVCQ-DVLKNVSICSDPEHHKEY-EHVQTTS 67

Query: 65  S-TFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVL-LAGLLGKLYFSIMITVNTMNDWP 122
           S  F Q+N I S +V +  A  LGS+SD  GR+ V+ L  +L  L   +++ V+ +++  
Sbjct: 68  SYIFLQFNAILS-LVSIPPAIMLGSWSDSAGRRSVMALPSVLSLLSGGLLLAVSLLDNIS 126

Query: 123 VEYVIYTAALPSALTGADLAIFAGCFAYIADVS--SVKNRTLRVGILD 168
           V + +  AAL   LTG  ++IF   F+Y+AD++  S   RTLR+ + +
Sbjct: 127 VYWTLMAAAL-MGLTGGHVSIFLSSFSYLADLTMGSSSTRTLRMAVAE 173



 Score = 43.6 bits (98), Expect = 0.006
 Identities = 23/88 (26%), Positives = 47/88 (53%)

Query: 174 TLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAY 233
           TL    A+  I  +++ A +    M+++ A   A   I   +IRS++S ++ PDE+G  +
Sbjct: 340 TLAKLSAVFRIASYILLALSNNTWMVFLVAVVGAPSGISQAVIRSLSSAIVGPDEQGAMF 399

Query: 234 AFLSVMENAVAIFASIVYTQIYNATIGT 261
           +F + +E    + A+ ++  +Y  T+ T
Sbjct: 400 SFSASVEATCILIAATIFNGLYPLTLPT 427


>UniRef50_Q16VM5 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 451

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 58/227 (25%), Positives = 105/227 (46%), Gaps = 21/227 (9%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHG----------YSTEICYNISKHADINK 58
           VEP  F +   + ++ +I     V+QTC +  G            T +  N +  + + +
Sbjct: 1   VEPVAFLHSFGWSLSEIILTNQIVYQTCVVTLGGPDVESCAIMKQTGVAENETLASHLEQ 60

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMIT-VNT 117
           +VQ   +T      + + VVP  +A FLG +SDK GRK V+     G +   +++  V  
Sbjct: 61  KVQPYAATVTMTVVLLTSVVPAMVALFLGPWSDKFGRKPVIAIASTGYMLTEMLVAWVCY 120

Query: 118 MNDW----PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLS 173
           M+++    P  YV+  A +P +++G      AG F+Y++DV++ +NRTLR+G+L      
Sbjct: 121 MSNYYALSPWWYVV--ANIPVSISGGYSVFNAGLFSYMSDVTNERNRTLRMGVLQ----G 174

Query: 174 TLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSIT 220
              +G+ I  +    +    +   M  +      LG +   L+   T
Sbjct: 175 CTMLGVLIGLLASSYMIDSVSATVMFLISTAGMFLGIVYLALVTKET 221



 Score = 37.5 bits (83), Expect = 0.38
 Identities = 22/94 (23%), Positives = 45/94 (47%), Gaps = 1/94 (1%)

Query: 166 ILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLP 225
           + +++ LS L +   +  +  +L+      G  +Y+      L  +    IRS+ S +LP
Sbjct: 322 LFNISDLSLLAIS-TMNQLGDYLIKGFAQEGWQLYLTTLMTPLKGVDGAAIRSMLSSILP 380

Query: 226 PDERGVAYAFLSVMENAVAIFASIVYTQIYNATI 259
            D+ G +Y+    ++    + +  ++T IYN TI
Sbjct: 381 KDDIGKSYSMDLSVKAITPLISVFLFTSIYNRTI 414


>UniRef50_A7SHN9 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 383

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 45/165 (27%), Positives = 83/165 (50%), Gaps = 4/165 (2%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTV 64
           K ITVEP +F YM    ++  + Q     + C   H Y+T  C N+S + +    VQ + 
Sbjct: 2   KSITVEPVLFLYMFCTFMSFPLLQQLAYRKICK-EH-YNTSACNNLSDYQNEQNYVQTST 59

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT-MNDWPV 123
           S + ++  +A  +  +  +  LG++SD+ GRK +++   +G +  +I   +N       V
Sbjct: 60  SNWMRYQALALALPSIASSLVLGAWSDRVGRKAIMILPPVGNILMNINYMLNVHFFSLNV 119

Query: 124 EYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD 168
            Y+I    +     G    + +  F+Y+AD++   +RTLR+ IL+
Sbjct: 120 NYLIIGIVIAGTFGGFATTLLS-VFSYMADITDKSHRTLRISILE 163



 Score = 33.9 bits (74), Expect = 4.7
 Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 7/145 (4%)

Query: 96  KIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVS 155
           ++ LL  L G +   +++     ND     ++Y    P  L+ + L  F      I  + 
Sbjct: 245 RLYLLVVLFGAMSV-LLLNFGGFND---VIILYCLKEPLHLSSSILGYFLAEVFLIRGLG 300

Query: 156 SVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGK-MMYVGATAAALGPIVAP 214
            V    L   +L ++      +GI  +   G  ++      K MM+ GA  A    +  P
Sbjct: 301 VVLGMPLMTKLLKLSDYIIALLGITFS--CGMFIFFGLAKHKWMMFAGAVLALGDGLPIP 358

Query: 215 LIRSITSKLLPPDERGVAYAFLSVM 239
            +RSI SK + P E+G  +A ++ +
Sbjct: 359 CMRSIMSKCVQPSEQGSMFAAVACL 383


>UniRef50_Q17KH3 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 481

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 50/182 (27%), Positives = 88/182 (48%), Gaps = 15/182 (8%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTVSTFH 68
           +EP +F    A  ++  +     V+Q C ++ G +   C  + K  + + EVQ   +   
Sbjct: 27  LEPPIFLIFFALNVSTAVFTDQLVYQACTVSLGINRTECDKLGKEYE-SPEVQALEARVQ 85

Query: 69  QWNG-------IASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV-NTMND 120
            ++        +A  ++P F+  F+G +SD+ GRK VLL    G +   + ITV   +  
Sbjct: 86  PYSADILMAESLADSLLPAFMNLFIGPWSDRFGRKPVLLLTFTGCMLSHLFITVICALTS 145

Query: 121 W----PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLP 176
           W    P  Y I  + +PSAL+GA   +    F Y+ADV+S + R  ++ I++    S + 
Sbjct: 146 WYRLDPWYYAI--SFVPSALSGATCTMLTSVFCYLADVTSEQERGNKMSIMEAALYSGML 203

Query: 177 MG 178
           +G
Sbjct: 204 LG 205



 Score = 37.5 bits (83), Expect = 0.38
 Identities = 20/72 (27%), Positives = 35/72 (48%)

Query: 188 LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFA 247
           +V A  T    +Y+  T   L     P+ R+  SK   P++ G  ++F S  E  + + A
Sbjct: 369 IVIAVATEPWHLYLAITICMLKGATDPMTRAFISKGASPEDMGSIFSFSSTFEALMPLGA 428

Query: 248 SIVYTQIYNATI 259
           + +YT +Y  T+
Sbjct: 429 APLYTNVYKHTL 440


>UniRef50_UPI0000DB7E26 Cluster: PREDICTED: similar to CG30345-PA,
           partial; n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG30345-PA, partial - Apis mellifera
          Length = 290

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 60/235 (25%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHAD------I 56
           W +Y  V+P +   ++A  I++ I     +++TC I    +   C  + +++       I
Sbjct: 8   WKRYALVQPPIMMLVIAQAISSNILTDLIIYRTCSIILNINKTECLVLHENSSSAEALKI 67

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSI-MITV 115
           +  VQ   S       I   V+P  L+ FLG +SD  GRK ++L+G +G    S+    +
Sbjct: 68  DALVQPKTSLILMTKSIIESVIPALLSLFLGPWSDIYGRKSIILSGYIGWYCISLTYFLL 127

Query: 116 NTMNDWPVE-YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRV----GILDVT 170
           ++M  W +  + +  A +P A  G    I  G   Y++D+S+ + R  ++     ++ V 
Sbjct: 128 SSMTIWDINPWFLLIAYIPYACCGGFCIILLGTVCYLSDISNEQERGWQLAWMEALISVG 187

Query: 171 YLSTLPMGIAIAHITGH-LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLL 224
            L  +  G  I  I G+ LV+   T+  ++  G     L P  + +  SIT K L
Sbjct: 188 ILIGILAGPIIFKIYGYTLVFVIATICCIL-AGLHICFLVPETSHITDSITIKSL 241


>UniRef50_UPI0000E48DE8 Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 462

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 16/197 (8%)

Query: 7   ITVEPTMFFYMMAYMI----------TNVIEQTFYVFQTCHINHGYSTEICYN--ISKHA 54
           ITVEP +FF M++Y +            + E  F +      +    ++   N  ++ ++
Sbjct: 34  ITVEPVIFFMMLSYSLFIPLRLQYLTRRIAEDEFGIVDYNRADDPLCSKNGTNSGMTINS 93

Query: 55  DINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMIT 114
            +  +++  VS F  +    + V  LF    LG++SD+ GRK+ L+   +G   ++    
Sbjct: 94  TMEMDIEQQVSLFSLYLSATTSVPALFCTTLLGAHSDQAGRKVALIVPSIGFCVYAACYL 153

Query: 115 VNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
           + TM++  + Y++        L G    + AGCF+Y+AD+++ K R LR+ +LD   LS 
Sbjct: 154 IVTMHELNIWYLV-IGHFVLGLCGDFSLLLAGCFSYMADITTKKERALRIILLDC--LSF 210

Query: 175 LPMGIAIAHITGHLVYA 191
           +  GIA   + G+ ++A
Sbjct: 211 MAAGIAQVGV-GYWIHA 226



 Score = 40.3 bits (90), Expect = 0.054
 Identities = 14/46 (30%), Positives = 31/46 (67%)

Query: 214 PLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATI 259
           P++R+I SKL+ P E+GV +A +  +++   + + +++  +Y AT+
Sbjct: 394 PMLRTIMSKLVYPSEQGVMFACIGCLQSIAMVISPLIFNTLYYATL 439


>UniRef50_UPI00015B420D Cluster: PREDICTED: similar to adenylate
           cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to adenylate cyclase - Nasonia vitripennis
          Length = 433

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 48/189 (25%), Positives = 82/189 (43%), Gaps = 8/189 (4%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCH-INHGYSTEICYNISKHAD------ 55
           W +   +EP  FF M ++ I++ +     VF+TC  I  G     C  + +++       
Sbjct: 8   WRRLTFIEPVTFFIMFSFSISDSVITDMIVFKTCRKIMQGDEKNNCTILYENSSSDAAKA 67

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           + + VQ   +T          + P  L  FLG +SD  GRK +L    +G + +  +  +
Sbjct: 68  LQEIVQPHTATLLVLKSSIETLFPTILILFLGPWSDTNGRKPLLTFPFIGSIIYYSLFAI 127

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
            +  +    Y      L S+L G    I   CF YI DV+  +NR+ R+G LD       
Sbjct: 128 QSSFEIDT-YWFLIPCLISSLMGGFPTILLTCFCYITDVTDSQNRSWRLGFLDFVLFGGQ 186

Query: 176 PMGIAIAHI 184
            +G  ++ +
Sbjct: 187 LVGYLVSPV 195


>UniRef50_UPI0000D569FE Cluster: PREDICTED: similar to CG30345-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG30345-PA - Tribolium castaneum
          Length = 477

 Score = 69.7 bits (163), Expect = 8e-11
 Identities = 44/230 (19%), Positives = 103/230 (44%), Gaps = 12/230 (5%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNI-SKHAD-----INKEV 60
           I +E  +     A+++++ ++    +F+TC++  GY+   C  + SKH D     + K V
Sbjct: 11  IHIEVPLVLIFFAFIVSDSVKTNLIIFRTCYVTLGYNKSECALLGSKHTDNSTANLEKIV 70

Query: 61  QVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMND 120
           +   +  +    +    +       +G +SD+ GRK +L+  + G +   +++ +  + +
Sbjct: 71  EPYAALVNMVGLLVDGCISAVTCLVIGPWSDRFGRKPILIIPVFGFIVTYLLLALFAVLE 130

Query: 121 WPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIA 180
               + I   ++P  +TG   +       YI DV++  NR +R+G+ +    + L +GI 
Sbjct: 131 NLSPWYILLCSIPILVTGGVSSYLTVLLCYITDVTNENNRGMRMGVFE----ALLSLGIF 186

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERG 230
           + +++   ++A T    +  + +    L  +       I   +  P+  G
Sbjct: 187 LGNVSSSYIFAATNYSTVFLLSSACCLLNLLFTMFF--IPESITSPESEG 234



 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           I+   G LV         +Y  A + ALG +++P++RS+ SK++P DE G  +A +   E
Sbjct: 339 ISMFIGALVMGLAIYSWQVYAAAFSRALGGVLSPMVRSLVSKIVPNDEIGKVFALIVATE 398

Query: 241 NAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIV 278
           + + +  S ++T IYN TI T+    IF F  +   +V
Sbjct: 399 SLIGMGGSPIFTAIYNTTISTD--AGIFNFVAAGVYVV 434


>UniRef50_Q4SFY6 Cluster: Chromosome 7 SCAF14601, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 7
           SCAF14601, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 424

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 49/168 (29%), Positives = 85/168 (50%), Gaps = 8/168 (4%)

Query: 9   VEPTMFFYMMA-YMITNVIEQTFYV-FQTCHINHGY----STEICYNISKHADINKEVQV 62
           VEP +  Y  + ++I  +++Q  Y  F     N  Y    +T  C   S  +  ++EVQ 
Sbjct: 7   VEPVVALYAFSSFLIYPLVQQFVYRRFWEQLTNSTYPISDNTSRCAENSSQSSYHQEVQK 66

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWP 122
             S F  +  + S +  L +   L +YSD+ GRKI ++  L+G L +++     +  +  
Sbjct: 67  QASLFSLYTDLLSTLPSLAVTLLLVAYSDRAGRKITIIMPLIGTLIYTVSFLTVSYYELN 126

Query: 123 VEYVIYTAALPSALTGADLAIFAGCFAYIADV-SSVKNRTLRVGILDV 169
           + Y++  A+L S+L G       GCFAYIAD+ +    +T+R+  LD+
Sbjct: 127 L-YLLIGASLLSSLFGGLGTFLGGCFAYIADLCADGHQKTMRMAGLDM 173



 Score = 41.1 bits (92), Expect = 0.031
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 214 PLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTIS 273
           P++RS+ SK++P  E+G  +A LS  EN     +  V+  +Y AT+   Y   IF  +  
Sbjct: 357 PVLRSMMSKIIPKSEQGALFACLSFFENLTNSVSVAVFNSVYAATVAW-YPGFIFLMSAG 415

Query: 274 TQVI 277
             V+
Sbjct: 416 LCVV 419


>UniRef50_A7S0P7 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 438

 Score = 66.1 bits (154), Expect = 1e-09
 Identities = 51/174 (29%), Positives = 84/174 (48%), Gaps = 13/174 (7%)

Query: 5   KYITVEPTMFFYMMA-YMITNVIEQTFYVFQTCHINHGYSTEI-----CYNIS----KHA 54
           K+ T E  +F Y    +M   VI+Q  YV+     + G+  +      C NI+       
Sbjct: 8   KWRTPEIVVFLYAYGLFMHVPVIQQ--YVYSRIAKSKGFPYDAHKKTGCGNITILNATMQ 65

Query: 55  DINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMIT 114
            I +EVQ   S  H    + + +  + ++  +GS++D RGR+  L    LG    SI++ 
Sbjct: 66  HIEQEVQSLASYVHLGIVMFAALPSVVMSLLIGSWTDSRGRRPALFLPALGSTLESIVVI 125

Query: 115 VNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD 168
           +    +WP+ YV++  A  + L G+   I  G  AYIAD +    R+LR+ IL+
Sbjct: 126 LVMYFEWPI-YVLFVGASINGLCGSFTTIIMGTMAYIADTTHEDQRSLRLAILE 178



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 14/89 (15%), Positives = 47/89 (52%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           ++ +  ++++  +T   ++++   A      V P++R I S+++  DE+G  ++ ++ +E
Sbjct: 336 LSTMASYILFGFSTKIFIVFLVPFAGLFMGCVVPILRGIMSRIVSQDEQGALFSAVASLE 395

Query: 241 NAVAIFASIVYTQIYNATIGTEYINSIFY 269
               +  + ++  +Y A++   +   +F+
Sbjct: 396 MLCHLCGTFLFNSLYPASLKFHFPGFVFF 424


>UniRef50_Q9VA14 Cluster: CG15553-PA; n=3; Sophophora|Rep:
           CG15553-PA - Drosophila melanogaster (Fruit fly)
          Length = 497

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 47/198 (23%), Positives = 91/198 (45%), Gaps = 19/198 (9%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNI-SKHAD-----INKEVQV 62
           +EP +F  + ++M++  + +   ++Q C +   Y+   C  + SK+       I  E+Q 
Sbjct: 23  IEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDSKNTTTEIQAIETELQD 82

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWP 122
            V+       +   ++P     F+GS+SD+ GRK +++  L+G   FS    ++++  W 
Sbjct: 83  YVANMFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVG---FSASALISSIICWL 139

Query: 123 VEYVI-----YT-AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLP 176
             Y +     YT AA+P ++ G         F +I D + +K R  R+  +++     L 
Sbjct: 140 SSYYMVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALT 199

Query: 177 MGIAIAHITGHLVYAHTT 194
            G     +    VYA T+
Sbjct: 200 SG----SLLSSFVYAATS 213



 Score = 40.3 bits (90), Expect = 0.054
 Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 5/76 (6%)

Query: 199 MYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNAT 258
           +Y+         I  P+ R+I S ++PP + G  +A  +++++     A+ +YT IY  +
Sbjct: 396 LYLSVVLGIFRSIQGPMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKES 455

Query: 259 I-----GTEYINSIFY 269
           +     G  ++++ FY
Sbjct: 456 LASNPGGFNFLSAAFY 471


>UniRef50_Q17KH4 Cluster: Adenylate cyclase, putative; n=1; Aedes
           aegypti|Rep: Adenylate cyclase, putative - Aedes aegypti
           (Yellowfever mosquito)
          Length = 412

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 42/183 (22%), Positives = 89/183 (48%), Gaps = 10/183 (5%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHA------DINK 58
           + +  EP +F +  A  ++ +      ++QTC    G+    C  +   A      +I  
Sbjct: 100 RLVNFEPAVFLFCFALSLSEIELSHQIIYQTC-CEQGFQRSECLLVGTEANSPVVQEIEA 158

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMIT-VNT 117
           +V+   ++ +        V+P+F A  LG++SD+ GRK V++    G     + +T +N 
Sbjct: 159 QVKPVAASVNTVIVAIKSVIPVFGALLLGAWSDRYGRKPVVVITGCGLFVTYVALTGLNY 218

Query: 118 MNDW-PVEYVIYTAA-LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
           ++ +  V    Y  A +P ++TG    + A  +A+I+D+S+ + RT+++G +    ++  
Sbjct: 219 LSSFVQVNLWFYAIAFIPFSITGGIAILVATIYAFISDISNDQIRTIKMGFMSAVMVAGA 278

Query: 176 PMG 178
            +G
Sbjct: 279 ALG 281


>UniRef50_A7S9D8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 566

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 17/177 (9%)

Query: 5   KYITVEPTMFFYMMAYM--ITNVIEQTFYVFQT----CHINHGYSTEIC-------YNIS 51
           +Y  VEP +FFY   Y   +  V++  +Y F       + N   S E C        N S
Sbjct: 12  RYCGVEPVVFFYSYWYFLGLLAVLQYVYYRFSEDKGFPYRNLTESGEGCGDGGGFPLNSS 71

Query: 52  KHADINKEVQVTVSTFH-QWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFS 110
            H  +  EVQ   S  +  + G+ +  +  F+  F GSY+D+RGRK  L+A L+G +  +
Sbjct: 72  LH-QLEIEVQSASSELYLYYLGVWALSIS-FIVPFTGSYTDRRGRKPGLIAPLVGAILET 129

Query: 111 IMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGIL 167
           +++ +    + PV YV+    L + LTG +  +      Y+ D +  K +  R+ IL
Sbjct: 130 LVLVLVLYLELPV-YVLIVGGLVNGLTGNEATMMMATTCYVTDTTDDKQKAFRLSIL 185


>UniRef50_UPI0000584089 Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 496

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 10/175 (5%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICY-------NISKHAD-I 56
           ++ITVEP +    +A     VI +  Y+       H YS+ I         N   + D +
Sbjct: 63  RWITVEPILLLIALARKAM-VITRLQYLKHRIGEEHHYSSIIANLSVSSLCNDDNYTDTL 121

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVN 116
             E+Q   + +  +    S    LF    +G+ S+  GRK+ ++   +G +   ++  + 
Sbjct: 122 EDEIQQQTAVWSLYLYAMSTFPALFTTIVVGAISNLAGRKVAMMVPCIGYILQCVLFLII 181

Query: 117 TMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
                P+ +  + A L   ++G    +FAG  AYIAD +  + RTLR+ + +  Y
Sbjct: 182 AYAHLPL-WTFFIAELLQGISGGVALLFAGAHAYIADTTEKRQRTLRIAVTEGVY 235



 Score = 41.9 bits (94), Expect = 0.018
 Identities = 33/153 (21%), Positives = 66/153 (43%), Gaps = 5/153 (3%)

Query: 126 VIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHIT 185
           V+Y  A P   T  D+  +      +  V S+          +  ++  + +  A+A + 
Sbjct: 341 VLYGLAKPFCWTPIDVGFYTAVSLILPGVGSLVGGQFVYHFNNDYWMMHISLISAMA-MC 399

Query: 186 GHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAI 245
                A TT   ++Y G    A+   +APLIR + SK++   E+   + +   + N V  
Sbjct: 400 FTTALAKTT--PVLYSGLVVGAMSSFIAPLIRGLMSKMVGEHEQVSVFTYAGCVGNTVKF 457

Query: 246 FASIVYTQIYNATIGTEYINSIFYFTISTQVIV 278
            A ++   IY  T+ T  + ++ ++ +   VI+
Sbjct: 458 IAKVMAFSIYAGTVHT--LPTLTFYVLGFIVII 488


>UniRef50_A7RIK2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 262

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 3/110 (2%)

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           +  EVQ   S F   + +   +  L +  F+G ++D  GRK+ L+  +LG +  S ++T+
Sbjct: 43  LENEVQEHASQFDTSSVMCQALPALIMGLFIGPWTDSGGRKLALMVPVLGSILES-LLTI 101

Query: 116 NTMN-DWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRV 164
             M+  WP+ YVIY     + LTG   A+F    +YIAD+S       R+
Sbjct: 102 CVMHFSWPL-YVIYAGNALNGLTGFFSALFQVSMSYIADISDPSQIAFRL 150



 Score = 35.9 bits (79), Expect = 1.2
 Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 1/55 (1%)

Query: 205 AAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATI 259
           +A  GP++ P ++ + SK++P +E+G  +  +S +E    IF + V   IY  +I
Sbjct: 155 SALSGPLL-PSVKGMMSKMVPTEEQGSLFTGVSAVETLARIFGAAVVNAIYVRSI 208


>UniRef50_UPI000069FC22 Cluster: Thymic stromal cotransporter
           homolog.; n=4; Tetrapoda|Rep: Thymic stromal
           cotransporter homolog. - Xenopus tropicalis
          Length = 452

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 35/139 (25%), Positives = 69/139 (49%), Gaps = 5/139 (3%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTM 118
           ++Q  +S F+    +   + PL  A+ L   SDK   K+ +   L G L   + +    +
Sbjct: 58  DLQKAISNFYIIYNVVMGMTPLLSAYILAKISDKTSTKVTICVPLTGYLISRMFLLFVIL 117

Query: 119 NDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMG 178
            +WP+E +  +AA  + LTG     +AG  A+ +  S+   R+L++ I+++ Y      G
Sbjct: 118 FEWPIEVIFGSAAF-NGLTGWFTTYWAGVMAWASLASTESKRSLKLIIIELVYGLA---G 173

Query: 179 IAIAHITGHLVYAHTTVGK 197
            A + ++G+ ++ H  + K
Sbjct: 174 FAGSLVSGY-IFVHLNINK 191



 Score = 35.9 bits (79), Expect = 1.2
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 4/103 (3%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           I+   G L+ A      + Y+         I  P IRSI SK +     G  +A L +  
Sbjct: 345 ISFSCGILIMAFVRWTYLYYIARAVMLFSLITTPTIRSIISKHVKGSSYGKVFAVLQLAI 404

Query: 241 NAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
             V + +S    ++Y AT+  ++ +   +   ST  + FLSA+
Sbjct: 405 GVVYVSSSAGLNKLYQATL--DWYSGFCFLLFST--LGFLSAI 443


>UniRef50_Q4TCI9 Cluster: Chromosome undetermined SCAF6885, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF6885,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 279

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 38/112 (33%), Positives = 59/112 (52%), Gaps = 3/112 (2%)

Query: 58  KEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLG-KLYFSIMITVN 116
           +EVQ   + ++ +  +    V L +   LGS+SD  GR+ VL+   +G  L  ++ I V 
Sbjct: 2   QEVQTLTAQWNLYINLGGFSVGLLMVPLLGSWSDVAGRRPVLVVPCVGLALQAAVYILVM 61

Query: 117 TMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD 168
            +   PV Y +    L   L G    I A CF+Y+AD+S  ++RT RV IL+
Sbjct: 62  YLK-LPVVYFL-AGRLLCGLAGDFSVILAACFSYVADISDRRSRTFRVAILE 111


>UniRef50_UPI000065D141 Cluster: UPI000065D141 related cluster; n=1;
           Takifugu rubripes|Rep: UPI000065D141 UniRef100 entry -
           Takifugu rubripes
          Length = 414

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 6/167 (3%)

Query: 6   YITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYS---TEICYNISKHAD-INKEVQ 61
           +ITVEP +    +A   T+ +  T Y+++      GY+   T  C N+S   D + +EV 
Sbjct: 47  FITVEPLILLTNVAVTTTSSLT-TQYIYEVVSAEVGYNGSKTSGCSNVSLPLDPLQEEVD 105

Query: 62  VTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDW 121
              + ++ +  +    V L     LGS+SD  GR+ VLL   LG    +++  +      
Sbjct: 106 TLSAHWNLYMNLGVFSVGLLSVPLLGSWSDIAGRRPVLLLCSLGFTLQALLYILVIYLRL 165

Query: 122 PVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD 168
           PV Y +    + S L G    + A  ++Y+AD    K+ TLR+ IL+
Sbjct: 166 PVFYFVIGKVI-SGLFGDSNILMAISYSYVADNIDEKSLTLRLIILE 211


>UniRef50_A7RIS8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 509

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 51/192 (26%), Positives = 91/192 (47%), Gaps = 12/192 (6%)

Query: 4   YKYITVEPTMFFYMMAYMIT-NVIEQTFY--VFQTCHINHGYSTEICYNISKHA---DIN 57
           ++ +TVE T+FFY+   ++   V++Q  Y    +   IN+  +T IC     ++     N
Sbjct: 15  HRAVTVEITIFFYIAGMILELPVLQQYLYERAAKELKINNTSNTTICSPNDLNSTGQSAN 74

Query: 58  KEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT 117
             VQ   S +     +A  +  +  A  LG++SDK GRK ++L    G +  + +     
Sbjct: 75  DAVQEKASQYILAYNLALQLPAVLTACLLGTWSDKNGRKPLMLIVAFGAIVDASVALFTV 134

Query: 118 MNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD-VTYLS-TL 175
             D P+  +I    + + + G    +     AYIAD +  K R +++ +L+ + +LS TL
Sbjct: 135 YTDGPLYPLIIGGGI-NGVMGFYPTMVLALLAYIADTTPSKRRAIKLAVLEALAFLSGTL 193

Query: 176 ---PMGIAIAHI 184
                GI I H+
Sbjct: 194 GHFSSGIYIHHL 205


>UniRef50_Q6P9B3 Cluster: SLC46A3 protein; n=14; Amniota|Rep:
           SLC46A3 protein - Homo sapiens (Human)
          Length = 463

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 51/174 (29%), Positives = 79/174 (45%), Gaps = 12/174 (6%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHG-YSTEICYNIS-----KHADI-- 56
           K + VEP +F    A  +T  +  T YV++      G Y+     NIS     K + I  
Sbjct: 2   KILFVEPAIFLSAFAMTLTGPLT-TQYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFA 60

Query: 57  -NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
             +EVQ  VS F+    I+  +  L   F L S SD  GRK  ++   +G L  S+ + +
Sbjct: 61  FQEEVQKKVSRFNLQMDISGLIPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCL 120

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIAD-VSSVKNRTLRVGILD 168
                +P + +I +  +  A  G     +  CFAYI D     K +T+R+ I+D
Sbjct: 121 LCYFAFPFQLLIASTFI-GAFCGNYTTFWGACFAYIVDQCKEHKQKTIRIAIID 173



 Score = 34.7 bits (76), Expect = 2.7
 Identities = 18/76 (23%), Positives = 38/76 (50%)

Query: 184 ITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAV 243
           +TG  + A  +   MM++         +   ++RS+ SK++   E+G  +A ++ +E   
Sbjct: 336 MTGMAMTAFASTTLMMFLARVPFLFTIVPFSVLRSMLSKVVRSTEQGTLFACIAFLETLG 395

Query: 244 AIFASIVYTQIYNATI 259
            + A   +  IY+AT+
Sbjct: 396 GVTAVSTFNGIYSATV 411


>UniRef50_UPI00005889BC Cluster: PREDICTED: similar to HCP1 protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to HCP1 protein - Strongylocentrotus purpuratus
          Length = 485

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 49/172 (28%), Positives = 78/172 (45%), Gaps = 6/172 (3%)

Query: 54  ADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMI 113
           + +  ++Q T ST+  + G    +  LF+A  LGS SD+ GRK  L   + G L  ++  
Sbjct: 112 SSVEDDIQATTSTWLLYLGAIQAIPGLFMAIILGSVSDRLGRKPALALCVTGLLINTVFN 171

Query: 114 TVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLS 173
            V     +P+   I    L   L G    + +   AY+ DV+S K RT R+ +++     
Sbjct: 172 IVVIYFHFPIPAFI-PGDLIGGLCGGLALLLSTSAAYVCDVTSAKMRTFRIVVVETVLF- 229

Query: 174 TLPMGIAIAHITGHLVY-AHTTVGKMMYVGATAAALGPIVAPLIRSITSKLL 224
            +  GI    +   L Y A  T+ K  Y+     +LG  VA L+  +   LL
Sbjct: 230 -VGYGIGQIALGFTLQYSADPTLNK--YLLPLWISLGCAVASLVYILLPWLL 278


>UniRef50_Q96NT5-2 Cluster: Isoform 2 of Q96NT5 ; n=3;
           Homo/Pan/Gorilla group|Rep: Isoform 2 of Q96NT5 - Homo
           sapiens (Human)
          Length = 431

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 7/166 (4%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEI----CYNISKHADINKEVQVTV 64
           VEP +F    A ++   +  T Y++     + GY+       C N S    + +EV+   
Sbjct: 25  VEPLVFLANFALVLQGPLT-TQYLWHRFSADLGYNGTRQRGGCSNRSADPTM-QEVETLT 82

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVE 124
           S +  +  +   +V LF +  LG++SD  GR+ +L+   LG L  +++          V 
Sbjct: 83  SHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVG 142

Query: 125 YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVT 170
           Y +    L  AL G    + A  FA +ADVSS ++RT R+ +L+ +
Sbjct: 143 YFVLGRIL-CALLGDFGGLLAASFASVADVSSSRSRTFRMALLEAS 187


>UniRef50_Q96NT5 Cluster: Proton-coupled folate transporter; n=21;
           Euteleostomi|Rep: Proton-coupled folate transporter -
           Homo sapiens (Human)
          Length = 459

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 7/166 (4%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEI----CYNISKHADINKEVQVTV 64
           VEP +F    A ++   +  T Y++     + GY+       C N S    + +EV+   
Sbjct: 25  VEPLVFLANFALVLQGPLT-TQYLWHRFSADLGYNGTRQRGGCSNRSADPTM-QEVETLT 82

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVE 124
           S +  +  +   +V LF +  LG++SD  GR+ +L+   LG L  +++          V 
Sbjct: 83  SHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVG 142

Query: 125 YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVT 170
           Y +    L  AL G    + A  FA +ADVSS ++RT R+ +L+ +
Sbjct: 143 YFVLGRIL-CALLGDFGGLLAASFASVADVSSSRSRTFRMALLEAS 187



 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 48/83 (57%), Gaps = 1/83 (1%)

Query: 177 MGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFL 236
           +G+A  +I G +V+A  T+  +M+ G     L  ++ P+IR+  SKL+   E+G  ++ +
Sbjct: 337 IGLAF-NILGMVVFAFATITPLMFTGYGLLFLSLVITPVIRAKLSKLVRETEQGALFSAV 395

Query: 237 SVMENAVAIFASIVYTQIYNATI 259
           + + +   + AS ++  +Y AT+
Sbjct: 396 ACVNSLAMLTASGIFNSLYPATL 418


>UniRef50_UPI0000588588 Cluster: PREDICTED: similar to MGC80576
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80576 protein -
           Strongylocentrotus purpuratus
          Length = 458

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 33/155 (21%), Positives = 62/155 (40%), Gaps = 1/155 (0%)

Query: 7   ITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTVST 66
           + +   +F +M    +   I Q       CH   GYS ++C ++  H D    VQ   ST
Sbjct: 4   VVLRVILFVFMCGLAMQWPITQHLIFEMACH-RLGYSDDVCSDLGNHTDAEHAVQSQAST 62

Query: 67  FHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYV 126
              +      +     +  LG+ SDK GRK ++L  ++G    ++++   ++        
Sbjct: 63  IMTYQSFFCDIPGAVASLILGAQSDKVGRKRIMLLPIIGTTLLAVILLTGSLLHTTSLVA 122

Query: 127 IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRT 161
           I  ++    ++G      +    YI D +    RT
Sbjct: 123 IMASSFALGVSGGIGTFMSTVTNYITDTTPEDQRT 157


>UniRef50_A1Z7R6 Cluster: CG8046-PA, isoform A; n=5; Sophophora|Rep:
           CG8046-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 519

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 23/200 (11%)

Query: 9   VEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICY-----NISKHAD-INKEVQV 62
           +EP +   + AY  ++ + +   ++Q+C    GY   +C      NI+     I ++VQ 
Sbjct: 64  LEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGYPDSVCQLLGTKNITNETKRIEEQVQP 123

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLG---------KLYFSIMI 113
             +       +    +P F   F GS++D  GRK +L+   LG          + +  M 
Sbjct: 124 YAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSFLGYGLQYLISAAIAYCAMY 183

Query: 114 TVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLS 173
           T   ++ W   YV+  + +P +  G+ +        +IADVS  K R+ R+    + Y  
Sbjct: 184 TQGLVSPW--WYVL--SIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSYRM----IAYEL 235

Query: 174 TLPMGIAIAHITGHLVYAHT 193
            + +G+ +  +     Y  T
Sbjct: 236 AIYVGLLLGSLGSGYAYEAT 255



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           ++H +  L+         +YV         +V P+ R++ + LLP DERG  +A L V++
Sbjct: 400 LSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQ 459

Query: 241 NAVAIFASIVYTQIYNATIGTE 262
               + +S +Y  IY  T+ TE
Sbjct: 460 ALSPLISSTLYVAIYTRTLNTE 481


>UniRef50_A7STS4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 432

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 19/183 (10%)

Query: 7   ITVEPTMFFYMMAYMI-TNVIEQTFYVFQ--------TCHINHGYSTEICYNIS------ 51
           ITVEP +F Y    ++   VI+Q  Y+ Q        T   N+  S   C  I       
Sbjct: 3   ITVEPVIFCYAFGIILHVPVIQQ--YIHQRLSEGKGLTYEYNNTDSRTTCEPIQMANSSE 60

Query: 52  KHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSI 111
           +  ++ KEVQ   S       ++     L +A  LG++SD+ GR+  +   + G    S 
Sbjct: 61  ETLELQKEVQAEASYMQMGLVLSVSTPSLLVALLLGAWSDRAGRRRAMAMPIFGSAVESA 120

Query: 112 MITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD-VT 170
           +I V    + PV +++  A   +   G    +    F+YIAD++    R  R+GIL+ + 
Sbjct: 121 IILVIMYFELPVTFLL-LAEFINGSCGFFPTMVLSVFSYIADITEESQRAFRLGILEAIA 179

Query: 171 YLS 173
           ++S
Sbjct: 180 FIS 182



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 32/138 (23%), Positives = 68/138 (49%), Gaps = 6/138 (4%)

Query: 125 YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHI 184
           +V+Y    P       +  + G   ++  V +V    L+   L ++  + + +G+ ++ I
Sbjct: 280 FVLYALDRPLCCNAILIGYYLGLSFFVQAVGAVLG--LKYLRLCLSETALMQVGM-VSII 336

Query: 185 TGHLVYAHTTVGKMMYVGAT---AAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMEN 241
           +  +V A  T  K ++VG +    A LG +  P IR++ SK++  D +G  +A ++ +E 
Sbjct: 337 SSLVVMAFVTSKKTLFVGKSLPFVACLGGVPTPTIRAMMSKMVDADGQGALFAAVASLET 396

Query: 242 AVAIFASIVYTQIYNATI 259
              +  ++V+  IY  +I
Sbjct: 397 LCTLLGALVFNSIYPYSI 414


>UniRef50_UPI000054694C Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 475

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 9/169 (5%)

Query: 9   VEPTMFFYMMA-YMITNVIEQTFYV---FQTC-HINHGYSTEICYNISKHADINKEVQVT 63
           +EP +  Y  A +M   +++Q  Y    F+    I    S   C +   +  +++ VQ  
Sbjct: 7   IEPAVGLYAFAMFMFYPLLQQYVYRRLWFELSGFIYTSESLSHCSSNHSYITLHQAVQKE 66

Query: 64  VSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPV 123
            S F   + +   +  L  A  L SYSD  GRK+ ++  L+G+   ++   + +   + +
Sbjct: 67  TSLFLLHSELCFLIPSLISALLLVSYSDYCGRKVAIVPPLVGEALHALSYVLVSRFSFSL 126

Query: 124 EYVIYTAALPSALTGADLAIFAGCFAYIADVSSVK---NRTLRVGILDV 169
            Y++  ++  S L G    +  GCFAY+AD+        +T+R+  LD+
Sbjct: 127 NYLL-ASSFMSGLMGGPPTLIGGCFAYVADLCGEDLEGQKTVRMARLDM 174



 Score = 36.7 bits (81), Expect = 0.67
 Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 22/173 (12%)

Query: 111 IMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVT 170
           I+  +NT   W   +V Y +AL +A+    L  FAG         ++ +R L    + + 
Sbjct: 292 ILYELNTPLCWSEVFVGYGSALSTAIY---LVSFAGV--------ALLSRCLPDAYIILL 340

Query: 171 YLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERG 230
            L ++  G+ +A       +A TT+  +M++      L  +  P++RS+ SK++   E+G
Sbjct: 341 GLMSVAAGLIMA------AFAKTTL--LMFLVRLPLLLSIMPTPVLRSMMSKIVSGSEQG 392

Query: 231 VAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
             +A ++ +E      +  V+  IY AT+      S F F ++  + V  SAL
Sbjct: 393 AMFACVAFVEMLSVGVSFTVFNSIYAATLSW---FSGFSFLLAAGLTVIPSAL 442


>UniRef50_Q9BY10 Cluster: Thymic stromal cotransporter homolog;
           n=16; Amniota|Rep: Thymic stromal cotransporter homolog
           - Homo sapiens (Human)
          Length = 475

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 1/119 (0%)

Query: 51  SKHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFS 110
           S    +  + Q  +S F+    +   + PL  A+ LG  SD+  RKI +   LLG L   
Sbjct: 61  SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSR 120

Query: 111 IMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDV 169
           + + +  + DWPVE  +Y AA  + L G   A ++G  A  +  SS   R++R+ ++D+
Sbjct: 121 LGLLLKVLLDWPVEV-LYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDL 178



 Score = 33.1 bits (72), Expect = 8.2
 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 1/84 (1%)

Query: 185 TGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVA 244
           +G L+ A      M Y+         I    IRS  SKL+     G  +  L +      
Sbjct: 360 SGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTG 419

Query: 245 IFASIVYTQIYNATIGTEYINSIF 268
           +  S +Y +IY  T+   ++ S F
Sbjct: 420 VVTSTLYNKIYQLTMDM-FVGSCF 442


>UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1;
           Bdellovibrio bacteriovorus|Rep: Tetracycline-efflux
           transporter - Bdellovibrio bacteriovorus
          Length = 367

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 9/117 (7%)

Query: 73  IASHVVPLFLAF-FLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAA 131
           I+ + +  FLA   LG+ SD+ GR+ VLL  LL   +  I++        P   +++   
Sbjct: 19  ISIYALMQFLASPLLGALSDRFGRRSVLLISLLVAGFDYILMAYA-----PTLEILFAGR 73

Query: 132 LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
           + + LTGA++ +     AYIADVS+ +NR+   G++   +     +G AI  + GHL
Sbjct: 74  IIAGLTGANITV---AMAYIADVSNDENRSANFGMVGAAFGLGFIIGPAIGGLLGHL 127



 Score = 36.3 bits (80), Expect = 0.88
 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)

Query: 180 AIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVM 239
           A  +    + Y   T G MMY     +A+     P ++S+ S   PP E+G     L  +
Sbjct: 255 AFGYAVSFIFYGMATEGWMMYAILILSAVFWTSPPALQSLISHKTPPQEQGELQGSLVSL 314

Query: 240 ENAVAIFASIVYTQIY----NATIGTEYINSIFYF 270
            +  AI   +V T+++    +   GT Y+    Y+
Sbjct: 315 SSLAAIITPLVTTKLFAHFSSGNPGTLYLPGAPYY 349


>UniRef50_UPI0000E46FBF Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 397

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 54/222 (24%), Positives = 87/222 (39%), Gaps = 15/222 (6%)

Query: 5   KYITVEPTMFFYMMA----------YMITNVIEQTFYVFQTCHINHGYSTEICYNISKHA 54
           ++ITVEP +    MA          Y+   +    F        N     +     S   
Sbjct: 36  RWITVEPLLILSNMASAGLLVTRLQYLRARIAHDKFNQTSDYGANESSECDEAIQNSSSI 95

Query: 55  DINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMIT 114
            + + +QV +S +       S    +F     GS SD+ GR+I L+  ++G +    +  
Sbjct: 96  QLQQAIQVELSLYSLILNALSTFPAIFSTILFGSLSDRIGRRIGLVVPIIGLVIQCALYV 155

Query: 115 VNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
                  P+ +V + A     L G    + +   AYIADV+SV+ RT R+ I +   +  
Sbjct: 156 TIFYAHLPI-WVCFVADTLQGLAGGYGLLLSTASAYIADVTSVEQRTWRLVIAEAALV-- 212

Query: 175 LPMGIAIAHITGHLV-YAHTTVGKMMYVGATAAALGPIVAPL 215
           L  G+ I  I G ++ Y    V     +G     L   V PL
Sbjct: 213 LGSGV-IQPINGFIIQYCGIGVAFCTSLGVALPGLLYAVCPL 253


>UniRef50_UPI0000588A26 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 483

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 6/167 (3%)

Query: 5   KYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNIS---KHADIN-KEV 60
           + ++VEP +F  ++A     V  +T YV +    ++ Y+     N S   K AD   +++
Sbjct: 26  RVVSVEPVIFL-ILAVQGVLVNLRTQYVEERLAADNNYTLPEAGNCSAANKSADATGRQI 84

Query: 61  QVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMND 120
           +   S +  +    S  +P+F    L + SD  GRK +L+   LG L  S +  +     
Sbjct: 85  ESETSLWVMYMKSTSVFIPIFTGTILIAASDIVGRKPILIINALGHLLASTVFLLLAWLH 144

Query: 121 WPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGIL 167
            P+  V   A     L+G  +   +  FAYIAD S+ K+R  +  I+
Sbjct: 145 LPL-IVAVAAECILGLSGDSIVSISVSFAYIADTSTGKSRVTKYTII 190



 Score = 37.5 bits (83), Expect = 0.38
 Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 1/91 (1%)

Query: 194 TVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQ 253
           T   ++YV   A +L  +   +I    S ++   ERG A+A LS+  +   + + I+   
Sbjct: 365 TTNVLVYVAVAAGSLRTLPDSIIEFFLSNMVSSHERGTAFALLSIAASIGKVLSPILLNA 424

Query: 254 IYNATIGTEYINSIFYFTISTQVI-VFLSAL 283
           +Y   +   +    FY   +   + + L+A+
Sbjct: 425 VYAKAVLLNFPELTFYLAAAIYALPILLTAI 455


>UniRef50_A7RHU0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 515

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 36/132 (27%), Positives = 63/132 (47%), Gaps = 6/132 (4%)

Query: 39  NHGYSTEICYNISKHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIV 98
           NHG +T+    +     +  EVQ   S+   +  IA+ +   F+A F+G Y+DK+GRK  
Sbjct: 86  NHGNATDDRLKL-----LEIEVQTETSSLILYYIIAATMTTFFIAPFMGPYTDKKGRKPG 140

Query: 99  LLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVK 158
           L+  L G +  +I+  +      P+ + +   A  + L+G+   I     +YIAD  S +
Sbjct: 141 LVIALTGAMVETILTLLILHLKLPL-WTMIVGAFINGLSGSINTILLSVMSYIADSVSPE 199

Query: 159 NRTLRVGILDVT 170
               R  ++  T
Sbjct: 200 RLGFRYAVMQFT 211



 Score = 37.9 bits (84), Expect = 0.29
 Identities = 39/203 (19%), Positives = 88/203 (43%), Gaps = 15/203 (7%)

Query: 78  VPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALT 137
           + +F+  F   Y    GRK + +  +L  L  +I+ TV T     +  ++       +L 
Sbjct: 274 IKVFIRVFTKDYD--AGRKNLYM--ILTFLGINILATVGTGTAQLLFVLLRPLCWAPSLI 329

Query: 138 GADLAI--FAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTV 195
           G  LA   F G       +S +K     + I+ V Y+S +         +G L++A +  
Sbjct: 330 GYYLAYKYFTGGLGGAVMISLLKKCLNELNIVRVGYISVM---------SGLLLFAFSDR 380

Query: 196 GKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIY 255
             M+++G   +    +  P+   ++SK++  D++G  +A + ++     +  + ++  IY
Sbjct: 381 TWMVFLGPAVSFARGVTDPIFLDMSSKIVSQDDQGSLFAVVGILSTIGELVGTSLFNNIY 440

Query: 256 NATIGTEYINSIFYFTISTQVIV 278
             ++   +   +F  +    +I+
Sbjct: 441 PMSLRFGFPGLVFVISAGIFLII 463


>UniRef50_P02981 Cluster: Tetracycline resistance protein, class C
           (TetA(C)); n=117; root|Rep: Tetracycline resistance
           protein, class C (TetA(C)) - Escherichia coli
          Length = 396

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 36/101 (35%), Positives = 59/101 (58%), Gaps = 11/101 (10%)

Query: 73  IASHVVPLFL-AFFLGSYSDKRGRKIVLLAGLLG-KLYFSIMITVNTMNDWPVEYVIYTA 130
           +A + +  FL A  LG+ SD+ GR+ VLLA LLG  + ++IM T       PV +++Y  
Sbjct: 49  LALYALMQFLCAPVLGALSDRFGRRPVLLASLLGATIDYAIMATT------PVLWILYAG 102

Query: 131 ALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
            + + +TGA  A+ AG  AYIAD++  ++R    G++   +
Sbjct: 103 RIVAGITGATGAV-AG--AYIADITDGEDRARHFGLMSACF 140


>UniRef50_UPI000023DD03 Cluster: hypothetical protein FG06142.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG06142.1 - Gibberella zeae PH-1
          Length = 539

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 12/133 (9%)

Query: 36  CHINHG-YSTEICYNISKHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRG 94
           CHI++   ST+I   +    D   EVQ  +     WNG+ + ++ L +AF  G+ SDK G
Sbjct: 94  CHIHYNDTSTDIIDEMKCKVD---EVQSQLGYLFGWNGLVTSLIGLIVAFPYGTMSDKIG 150

Query: 95  RKIVLLAGLLGKLY------FSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCF 148
           RK +++   +G         FSI     ++ D P  Y++          G    + +  +
Sbjct: 151 RKPIVMFSWIGIAICFLFAPFSIKAFHGSLRDRP--YLLVLGGFFQVFGGGVPVLMSTLY 208

Query: 149 AYIADVSSVKNRT 161
           +  ADVS+ +N++
Sbjct: 209 SIAADVSTEENKS 221


>UniRef50_A3IH26 Cluster: Multidrug resistance protein, putative;
           n=1; Cyanothece sp. CCY 0110|Rep: Multidrug resistance
           protein, putative - Cyanothece sp. CCY 0110
          Length = 423

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 10/125 (8%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LGS SD+ GRK +L+  L G +  +++ +  T     V +++Y A +   LTG + ++  
Sbjct: 68  LGSLSDRLGRKSILIVSLAGTVVANMVASFAT-----VAWLLYAARVLDGLTGGNTSV-- 120

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL-VYAH-TTVGKMMYVGA 203
              A I+D++    RT   GI   T+     +G  ++++   L  +A  +++G    V A
Sbjct: 121 -ARAVISDITDASQRTKAFGIFSATFRLGFVVGPFLSYLAQQLPTFAGISSLGMSFVVSA 179

Query: 204 TAAAL 208
             A++
Sbjct: 180 AIASI 184


>UniRef50_Q7K0G5 Cluster: SD10604p; n=2; Sophophora|Rep: SD10604p -
           Drosophila melanogaster (Fruit fly)
          Length = 439

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/88 (26%), Positives = 43/88 (48%)

Query: 174 TLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAY 233
           TL +    + I  +L     T+   MY+  T      I  P+ R+I S ++PP + G  +
Sbjct: 313 TLALLAFFSEILNNLAKGFATMPWHMYLSVTLGVFRSISGPMCRTIVSNIVPPSDLGKIF 372

Query: 234 AFLSVMENAVAIFASIVYTQIYNATIGT 261
           +  +V+++     A+ +YT IY  ++ T
Sbjct: 373 SIKNVLQSFAPFVAAPLYTLIYKRSLTT 400



 Score = 33.1 bits (72), Expect = 8.2
 Identities = 16/67 (23%), Positives = 32/67 (47%)

Query: 130 AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLV 189
           AA+P +L G +       F +I+D++  K+R  R+  ++  +   L  G  ++      V
Sbjct: 31  AAVPHSLLGGNCVFSVAAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLLSSFVYAAV 90

Query: 190 YAHTTVG 196
            +  T+G
Sbjct: 91  GSAATIG 97


>UniRef50_A6U8Y2 Cluster: Major facilitator superfamily MFS_1; n=8;
           Rhizobiales|Rep: Major facilitator superfamily MFS_1 -
           Sinorhizobium medicae WSM419
          Length = 421

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 8/119 (6%)

Query: 70  WNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYT 129
           W  +    +  F A  +G+ SD+ GR+ +LLA +L     +++  + T + W +      
Sbjct: 53  WLLLVYSAMQFFFAPLIGNLSDRFGRRPILLASVLTFAIDNLICALAT-SYWML------ 105

Query: 130 AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
             +  +L G   A F    AYIADVS+ +NR    G++ + + +   +G  I  + G L
Sbjct: 106 -FIGRSLAGISGASFGTASAYIADVSNDENRAKNFGLIGIAFGTGFALGPVIGGVLGEL 163



 Score = 40.7 bits (91), Expect = 0.041
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 1/82 (1%)

Query: 174 TLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAY 233
           T  +G+    + G   YA    G M+Y    A AL  +  P +RSI S  +PP  +G   
Sbjct: 286 TAALGLTFTAL-GMAGYAAAWEGWMVYAVIVATALESLADPPLRSIASVHVPPSAQGELQ 344

Query: 234 AFLSVMENAVAIFASIVYTQIY 255
             L+ + +   I   +++TQI+
Sbjct: 345 GALTSISSMTTIIGPLMFTQIF 366


>UniRef50_Q6FJ82 Cluster: Similar to sp|P46996 Saccharomyces
           cerevisiae YJL163c; n=1; Candida glabrata|Rep: Similar
           to sp|P46996 Saccharomyces cerevisiae YJL163c - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 545

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 44/190 (23%), Positives = 84/190 (44%), Gaps = 16/190 (8%)

Query: 1   MPWYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKE- 59
           +PWY+    +P+ F   +  M+  + E T Y+     I      ++C +IS      +E 
Sbjct: 58  LPWYQ----KPSTFLICLLIMLIALAE-TLYMTPIIIIT---KDKVCESISNGQIKGEET 109

Query: 60  ------VQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGR-KIVLLAGLLGKLYFSIM 112
                 VQ  +S       I S V+  F+A  +G  SD+ GR  + +  GL+  L  +  
Sbjct: 110 ICDPIKVQTILSEISSMTIIISGVISTFMAGKMGELSDRFGRVHVFIYIGLIRLLGNAAH 169

Query: 113 ITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYL 172
           +     +    ++ I  A   ++ +G   AI A   +Y++D+   +NR++  G +     
Sbjct: 170 VYALWPSTTYYKWFIILAGSLNSFSGGMYAIIANANSYLSDIVEPENRSVSFGKVTSALF 229

Query: 173 STLPMGIAIA 182
           +T+ +G  +A
Sbjct: 230 ATMGVGFLLA 239


>UniRef50_A3ZND9 Cluster: Multidrug resistance protein; n=1;
           Blastopirellula marina DSM 3645|Rep: Multidrug
           resistance protein - Blastopirellula marina DSM 3645
          Length = 433

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 23/85 (27%), Positives = 49/85 (57%), Gaps = 5/85 (5%)

Query: 87  GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG 146
           G  SD+ GR+ V++ GL G + F  +  + T  +W   ++++ A + + + GA ++    
Sbjct: 73  GLLSDRIGRRPVIMIGLSGSVIFYAIFGIAT--EWQCIWLLFVARIGAGIAGATIST--- 127

Query: 147 CFAYIADVSSVKNRTLRVGILDVTY 171
             AYIAD +S++NR+  + ++ + +
Sbjct: 128 AQAYIADTTSLENRSKGMALIGMAF 152


>UniRef50_Q07282 Cluster: Tetracycline resistance protein, class E
           (TetA(E)); n=85; root|Rep: Tetracycline resistance
           protein, class E (TetA(E)) - Escherichia coli
          Length = 405

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 36/113 (31%), Positives = 59/113 (52%), Gaps = 10/113 (8%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLG-KLYFSIMITVNTMNDWPVEYVIYTAALPSA 135
           ++ +  A  LG +SD+ GR+ VLL  LLG  L +++M T +      V +V+Y   L + 
Sbjct: 52  MMQVIFAPLLGRWSDRIGRRPVLLLSLLGATLDYALMATAS------VVWVLYLGRLIAG 105

Query: 136 LTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
           +TGA  A+ A   + IADV+  ++RT   G++   +   +  G  I    G L
Sbjct: 106 ITGATGAVAA---STIADVTPEESRTHWFGMMGACFGGGMIAGPVIGGFAGQL 155


>UniRef50_UPI0000E45FD3 Cluster: PREDICTED: similar to MGC80576
           protein, partial; n=5; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to MGC80576 protein,
           partial - Strongylocentrotus purpuratus
          Length = 165

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 9/158 (5%)

Query: 5   KYITVEPTMFFYMMAY-MITNVIEQTFYVFQTCHINHGYST--EICYNISKHADINK-EV 60
           +YI  EP  F  +    M+T +  +T Y  +T   ++ Y+   +   N S     N  EV
Sbjct: 11  RYIATEPINFLILAIQGMLTTL--RTLYFRETLASDYEYNLLPQQDGNCSLPNVSNPLEV 68

Query: 61  QVTVST--FHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTM 118
           Q+   T  +  W    S  +P+  A  L + SD  GRK +L+    G L  S++  + ++
Sbjct: 69  QINSETALWVMWLASISTFIPILTASVLVATSDFIGRKPILIFSATGHLIASLIYLLVSV 128

Query: 119 NDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSS 156
              P+  V + AA+   + G   A    C AYIAD +S
Sbjct: 129 MRLPLA-VTFLAAITLGVCGDTSAAITVCTAYIADSTS 165


>UniRef50_UPI0000586F99 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 96

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 1/75 (1%)

Query: 203 ATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTE 262
           A     G I  P++RS  SKL    ERG+  AF+  M++   +   I+   IY+ T+ + 
Sbjct: 17  AGIGVFGAICFPVVRSQLSKLASEHERGLMLAFVGCMDSIGTLLTPIILNNIYSETV-SF 75

Query: 263 YINSIFYFTISTQVI 277
           Y   +F+F+ + ++I
Sbjct: 76  YPPLVFFFSAAFEII 90


>UniRef50_UPI0000D8EF0C Cluster: Thymic stromal cotransporter
           homolog.; n=3; Danio rerio|Rep: Thymic stromal
           cotransporter homolog. - Danio rerio
          Length = 420

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 6/167 (3%)

Query: 44  TEICYNISKHADI--NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLA 101
           T+  YN S  A    + + Q   S F     + S V+ +     L   +D  G K+ L++
Sbjct: 48  TQTVYNRSMKATAGDSNQAQAMSSRFLLIQSVLSSVMAMLSIIPLSRMADHHGPKVFLVS 107

Query: 102 GLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRT 161
             +G +     + +    + P+E+ +Y  +L   L+G     +AG  A  +  S  + RT
Sbjct: 108 SQMGSVLGMFTLVIFMYCEVPLEF-LYLGSLLHGLSGGGPMFWAGVAALASLSSEQRKRT 166

Query: 162 LRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAAL 208
           L++ I+D  +      G+    ++G+L     +V  +  +  TA AL
Sbjct: 167 LKLNIVDFCFGIA---GVVGGLLSGYLYQVGPSVLLLTAILITAVAL 210


>UniRef50_Q6CD09 Cluster: Similar to sp|P46996 Saccharomyces
           cerevisiae YJL163c; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|P46996 Saccharomyces cerevisiae YJL163c -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 594

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 4/132 (3%)

Query: 154 VSSVKNRTL--RVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPI 211
           V  + NR    R+  +D+T L  + +G+ I +  G    A  T G +  +   + +L   
Sbjct: 456 VMGILNRVFVTRLNHIDMTDLFVIRLGM-IVNCMGWFGVATATSGTLFLIAVASMSLSST 514

Query: 212 VAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFT 271
            +P ++S   K +   + G     L+++ +  ++ A IV+T IY  T+ T      FY  
Sbjct: 515 ASPTLQSALVKYIDRKDTGRLLGALALLHHICSLLAPIVFTSIYTLTVDTR-PELCFYIV 573

Query: 272 ISTQVIVFLSAL 283
                 +F++ L
Sbjct: 574 SGIFASMFVATL 585


>UniRef50_UPI0000549B24 Cluster: PREDICTED: similar to thymic
           stromal co-transporter; n=3; Danio rerio|Rep: PREDICTED:
           similar to thymic stromal co-transporter - Danio rerio
          Length = 424

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 1/111 (0%)

Query: 61  QVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMND 120
           Q  ++ F+    + +  +P   A  L    D+  RK+ ++  L+G      ++ ++   D
Sbjct: 44  QKAITNFNMTYNMIAKFMPFLPAILLAKVGDRGYRKVPIVVPLVGYFLSRGLLLLDVAFD 103

Query: 121 WPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
           WP++ V+Y   +   L G   + +AG  A ++  S  + R++ + + ++ Y
Sbjct: 104 WPLQ-VLYAVPVIHGLCGGFASYWAGVMALVSVSSGEEERSVSIMMTELVY 153



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 5/117 (4%)

Query: 145 AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGAT 204
           AG   +I     VK  T R+ + D    S + +G+ ++  TG    A  T   M ++  +
Sbjct: 274 AGSLLFITSFLGVKMFT-RLSLRDE---SMIMVGM-VSFATGIYFMAFVTTTPMYFLARS 328

Query: 205 AAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGT 261
                 I  P IRS+ SK +     G+ +  L +     ++  + +YT+IY AT+ T
Sbjct: 329 VTLFALIPMPTIRSLLSKQVKGTSYGITFVMLQLSFKLASLATTPIYTKIYQATLDT 385


>UniRef50_A6H1H8 Cluster: Major facilitator superfamily (MFS)
           permease; n=1; Flavobacterium psychrophilum
           JIP02/86|Rep: Major facilitator superfamily (MFS)
           permease - Flavobacterium psychrophilum (strain JIP02/86
           / ATCC 49511)
          Length = 411

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 13/119 (10%)

Query: 53  HADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIM 112
           H+DI+     T + +  W   A  ++    A  LG+ SD+ GR+ VLL+ L G     I 
Sbjct: 39  HSDIS-----TAAKYGGWLSFAYAIMQFVFAPVLGNLSDQYGRRPVLLSSLFGFSIDCIF 93

Query: 113 ITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
           +       W     ++     + +TGA  ++ + C   +AD+S+  NRT   G+++  +
Sbjct: 94  LAFAPSILW-----LFVGRTIAGITGASYSVASAC---VADISTDDNRTKNFGLINAGF 144


>UniRef50_Q6ZVG5 Cluster: CDNA FLJ42613 fis, clone BRACE3014005;
           n=9; Mammalia|Rep: CDNA FLJ42613 fis, clone BRACE3014005
           - Homo sapiens (Human)
          Length = 304

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 75  SHVVP-LFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALP 133
           S ++P L   F L S SD  GRK  ++   +G L  S+ + +     +P + +I +  + 
Sbjct: 4   SGLIPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFI- 62

Query: 134 SALTGADLAIFAGCFAYIAD-VSSVKNRTLRVGILD 168
            A  G     +  CFAYI D     K +T+R+ I+D
Sbjct: 63  GAFCGNYTTFWGACFAYIVDQCKEHKQKTIRIAIID 98


>UniRef50_Q17E18 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
           Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
          Length = 389

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 6/122 (4%)

Query: 73  IASHVVPLFLAFFLGSYSDKRG-RKIVLLAGLLGKLY--FSIMITVNTMNDWPVEYVIYT 129
           IA+ ++ + +  F GS+SD+ G RK  +L  +        +++I    M + P+E     
Sbjct: 10  IAAGLIEVVILLFAGSWSDRVGLRKPCILIPIAADTISLLALIICAIFMREIPLEVTGIL 69

Query: 130 AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLV 189
             L SAL G    I  G F+Y+  V++   RT R     +  +S +P  I     +GH+ 
Sbjct: 70  HQLISALGGGGHLILTGVFSYLTIVTTESQRTFRFACASIV-ISVIP--IIARFFSGHIF 126

Query: 190 YA 191
            A
Sbjct: 127 KA 128


>UniRef50_Q9UAZ6 Cluster: Putative uncharacterized protein Y4C6B.5;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein Y4C6B.5 - Caenorhabditis elegans
          Length = 469

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 32/162 (19%), Positives = 67/162 (41%), Gaps = 1/162 (0%)

Query: 3   WYKYITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQV 62
           + + + +E  +F YM+   +   + Q     + C I +  +   C N+S + D +K++Q 
Sbjct: 4   YLRMLGMEIPLFLYMLGSYLNYPVFQNLIYEKECLIKYQQNETFCRNVSAYYD-DKDIQA 62

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWP 122
             + F+  + +      L     LG+ +D    KI L+   +G +  +I     +     
Sbjct: 63  AANHFYFISSLTLLCPSLVTTLLLGAATDYWSIKIPLIIPYIGCILGTINYVFQSYFIHT 122

Query: 123 VEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRV 164
             Y +  +     L G  +AI +    Y    S ++ R+ R+
Sbjct: 123 SVYFLLISDALFGLCGGFIAIISTTLTYGVKTSMLRYRSYRI 164


>UniRef50_A7SJM3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 138

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 19/75 (25%), Positives = 40/75 (53%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           +A+I  +L+        MM++         +    +R+  SKL PPD++GV ++ + V++
Sbjct: 64  LANIASYLLTGFAETTLMMFLTLVPQIPQGLATASLRTAMSKLGPPDKQGVVFSVVGVVQ 123

Query: 241 NAVAIFASIVYTQIY 255
           +  A+ A ++Y  +Y
Sbjct: 124 SLCAVLAPLMYNTVY 138


>UniRef50_Q2G331 Cluster: Major facilitator superfamily MFS_1; n=1;
           Novosphingobium aromaticivorans DSM 12444|Rep: Major
           facilitator superfamily MFS_1 - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 405

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)

Query: 63  TVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWP 122
           T + +  W G     +    A  +G+ SD+ GR+ VLLA +L  L    ++     + W 
Sbjct: 42  TAAEYAGWLGAGYATMQFVFAPVIGNLSDRFGRRPVLLAAIL-MLGLDYLLQAMAPHFW- 99

Query: 123 VEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIA 182
               +    L + +TGA    F+  +AYIADV+  + R    G++ + +     +G A+ 
Sbjct: 100 ---WLIIGRLLAGVTGAS---FSAAYAYIADVTPPEKRAANFGMMGLAFGFGFVVGPAMG 153

Query: 183 HITG 186
            + G
Sbjct: 154 GLLG 157


>UniRef50_Q966P2 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 434

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 8/90 (8%)

Query: 70  WNGIASHV-VPLFLAFFL--GSYSDKRGRKIVLLAGLLGKLYFSIM--ITVNTMNDWPVE 124
           W+    ++ +P+   F +  G YSD RGRK  +L G+L  L  + M  +  +   DWP+ 
Sbjct: 27  WDNYYEYINLPIACVFGIIYGGYSDHRGRKYPMLIGILSVLVSNAMNILMWDENTDWPLA 86

Query: 125 YVIYTAALPSALTGADLAIFAGCF-AYIAD 153
           +   TA +   L   D  +   C  AYIAD
Sbjct: 87  WTYPTAVVTGVL--GDFLLTMSCINAYIAD 114



 Score = 34.7 bits (76), Expect = 2.7
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 171 YLSTLPMGIAIAHITGH-LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDER 229
           +  T  + +AI  +TG  L+        +++      +L  ++ P+  +  + ++  DE 
Sbjct: 284 FRDTFIICLAILSMTGCVLMIGLAQASWLIFASLAPGSLHGLLNPMSYTFIACIVEQDEI 343

Query: 230 GVAYAFLSVMENAVAIFASIVYTQIYNATI 259
           G AYA  SV +    I  S+V   IY AT+
Sbjct: 344 GKAYAISSVAQKLAGIAQSLVLQNIYIATV 373


>UniRef50_Q4SYZ4 Cluster: Chromosome 10 SCAF11883, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 10 SCAF11883, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 245

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 18/79 (22%), Positives = 43/79 (54%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           I+ I+G +V++      +++ G   + L  +  P+++S  SK++ P E+G  ++ L   E
Sbjct: 144 ISTISGMVVFSVANTTALIFTGYVLSLLYVVPTPVLKSKMSKMVNPSEQGALFSVLGSFE 203

Query: 241 NAVAIFASIVYTQIYNATI 259
             + + +  ++  +Y AT+
Sbjct: 204 TLLLLASYSIFNNLYPATL 222


>UniRef50_Q7Q1Q1 Cluster: ENSANGP00000016542; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000016542 - Anopheles gambiae
           str. PEST
          Length = 398

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 7/168 (4%)

Query: 77  VVPLFLAFFLGSYSDKRG-RKIVLLAGLLGKLY-FSIMI-TVNTMNDWPVEYVIYTAALP 133
           +V   +  F GS+SD+ G RK  +L  +   +  F + I +   M + P+E       L 
Sbjct: 4   IVQAVVLLFAGSWSDRVGLRKPCILVPIAADIVAFGVYILSAVFMREIPLEVAGIVPNLI 63

Query: 134 SALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLV-YAH 192
           +A +G    +  G ++Y+   +  K+RT R     V Y +T+P  I     +GHL  Y  
Sbjct: 64  NAFSGGVPLVVTGIYSYLTVCTDEKDRTFRFACTAVVY-ATVP--IVANFFSGHLFKYLG 120

Query: 193 TTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
                M+ V    +A+  +   +I  + +  +  D  G+ Y    + E
Sbjct: 121 FISTNMIPVIKMMSAIQLLFCCIISELCALCMVTDSIGLLYGLFVLKE 168



 Score = 35.9 bits (79), Expect = 1.2
 Identities = 31/106 (29%), Positives = 56/106 (52%), Gaps = 14/106 (13%)

Query: 177 MGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFL 236
           M IA++ +  +L Y  T++   ++ G+   A        IRSI SKL+  DE G   + L
Sbjct: 303 MAIAVSTVKPYLYYVATSID--VFEGSKMIA--------IRSIVSKLVGQDEIGKMLSIL 352

Query: 237 SVMENA-VAIFASI---VYTQIYNATIGTEYINSIFYFTISTQVIV 278
            ++++A VAI+ +I   VY +  +  IG+ ++ S  +  +S  + V
Sbjct: 353 GIVDSAQVAIYPTIYSTVYLKSQSFFIGSVFLLSEAFLLVSLGIYV 398


>UniRef50_Q8VVJ1 Cluster: TetA protein; n=5; Actinomycetales|Rep:
           TetA protein - Corynebacterium glutamicum
           (Brevibacterium flavum)
          Length = 407

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 11/116 (9%)

Query: 73  IASHVVPLFL-AFFLGSYSDKRGRKIVLLAGLLG-KLYFSIMITVNTMNDWPVEYVIYTA 130
           IA + V  F+ A  LG+ SD+ GR+ VLL  L G  + + ++ T + ++      V Y A
Sbjct: 54  IALYAVMQFIFAPVLGTLSDRFGRRRVLLVSLAGATVDYLVLATTSALS------VFYIA 107

Query: 131 ALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
              + +TGA  A+ A     IAD++    R  R G+L   Y   +  G A+  + G
Sbjct: 108 RAVAGITGATNAVTA---TVIADITPPHQRAKRFGLLSACYGGGMIAGPAMGGLFG 160


>UniRef50_Q1D6T2 Cluster: Putative multidrug resistance protein;
           n=1; Myxococcus xanthus DK 1622|Rep: Putative multidrug
           resistance protein - Myxococcus xanthus (strain DK 1622)
          Length = 400

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 11/126 (8%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LG  SD+ GR+ V+L  LLG      +   +T   W + + ++ + L   L GA     A
Sbjct: 59  LGRLSDRVGRRPVILLSLLGNAISMALFAYSTHVQW-LPW-LFASRL---LAGATAGNLA 113

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMM--YVGA 203
            C A +ADV+    R   +G++     + + +G+ +  + G L++ H      +   V A
Sbjct: 114 ACQAAVADVTDESGRAAGMGLVG----AGIGLGMVLGPVIGSLLHVHGAWAPPLAGAVMA 169

Query: 204 TAAALG 209
            AA LG
Sbjct: 170 AAAMLG 175


>UniRef50_A5G2L8 Cluster: Major facilitator superfamily MFS_1; n=1;
           Acidiphilium cryptum JF-5|Rep: Major facilitator
           superfamily MFS_1 - Acidiphilium cryptum (strain JF-5)
          Length = 405

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 21/74 (28%), Positives = 35/74 (47%)

Query: 187 HLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIF 246
           ++++        ++ G    ALG I  P IRS+ S+  P D++G     LS +E   AI 
Sbjct: 288 YMIFGVAPTASWLFAGVGLMALGSIANPAIRSMLSRAAPADQQGRMNGALSSIEGLTAIV 347

Query: 247 ASIVYTQIYNATIG 260
           A +    ++ A  G
Sbjct: 348 APLTGAVVFEAFSG 361


>UniRef50_A3UGP9 Cluster: Probable transporter; n=1; Oceanicaulis
           alexandrii HTCC2633|Rep: Probable transporter -
           Oceanicaulis alexandrii HTCC2633
          Length = 415

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 11/123 (8%)

Query: 69  QWNGIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEY 125
           +W GIA+ V  L    F   +G  SD+ G + VLL  L      ++M+    M       
Sbjct: 58  RWGGIATFVFALMQFVFSPIIGGLSDRFGCRPVLLLSLT-----ALMVDFLLMGLAHALV 112

Query: 126 VIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHIT 185
           V + A L   L+G   A  +   AYIAD+S+ + R  R G+L     +   +G A+  + 
Sbjct: 113 VFFIARL---LSGVFAATHSTANAYIADISTPEERARRFGLLGAAMGAGFVLGPALGGLL 169

Query: 186 GHL 188
           G L
Sbjct: 170 GEL 172



 Score = 33.1 bits (72), Expect = 8.2
 Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 188 LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFA 247
           L  A TT+  ++Y+    A    +  P ++ + ++  PPD +G     LS +   V I +
Sbjct: 310 LATAPTTL--VLYLWLLPALFTGMEGPALQKVMTERTPPDAQGELQGGLSGLGAIVLILS 367

Query: 248 SIVYTQIYNA 257
            ++YTQ++ A
Sbjct: 368 PLIYTQLFFA 377


>UniRef50_Q8INF8 Cluster: CG31321-PB; n=3; Sophophora|Rep:
          CG31321-PB - Drosophila melanogaster (Fruit fly)
          Length = 601

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 17/54 (31%), Positives = 29/54 (53%)

Query: 6  YITVEPTMFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKE 59
          Y+ +EP  FFY MA +   V  Q F + + C +N GY+  +C  +   +++  E
Sbjct: 36 YLVIEPFFFFYFMASVFNAVAMQNFPLDKACRVNLGYNKIVCDTMLDKSELGIE 89



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 77  VVPLFLAFFLGSYSDKRG-RKIVLLAGLLGK-LYFSIMITVNTM-NDWPVEYVIYTAALP 133
           + PL +  F G ++D+   RK  ++  ++G+ L F+  I  +      P+E+  Y  A+ 
Sbjct: 144 IFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPMEFGAYCEAIV 203

Query: 134 SALTGADLAIFAGCFAYIADVSSVKNRTLRVGI 166
            AL G         ++YI   +  ++R  R GI
Sbjct: 204 PALFGGLTFCLMAIYSYITIATPEEDRVFRFGI 236


>UniRef50_A3I9G6 Cluster: Multidrug-efflux transporter; n=1;
           Bacillus sp. B14905|Rep: Multidrug-efflux transporter -
           Bacillus sp. B14905
          Length = 392

 Score = 41.1 bits (92), Expect = 0.031
 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 81  FLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGAD 140
           F A F G  SDK GRK ++L GL+G   FS+   + ++    +  ++Y + +   L    
Sbjct: 59  FTAPFWGMLSDKVGRKQLILTGLIG---FSLSFVIFSLFIDNLA-ILYVSRVVGGLFSG- 113

Query: 141 LAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGH 187
            A++     +IAD+SS + R   +G + ++       G AI  + GH
Sbjct: 114 -ALYTAVTGFIADMSSEETRNKYMGFMGMSIGLGFIFGPAIGGMLGH 159


>UniRef50_Q9RX43 Cluster: Tetracycline-efflux transporter; n=2;
           Deinococcus|Rep: Tetracycline-efflux transporter -
           Deinococcus radiodurans
          Length = 407

 Score = 40.7 bits (91), Expect = 0.041
 Identities = 41/147 (27%), Positives = 68/147 (46%), Gaps = 16/147 (10%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LG+ SD+ GR+ VLL  L G +    ++   + N W     +    L + +TGA L +  
Sbjct: 68  LGTLSDRFGRRPVLLLSLAG-MVLDYLLLFFSPNLW----WLLVGRLIAGVTGASLTV-- 120

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATA 205
              AYIADV++ ++R    G L  T+     +G  +  + G  +  H      ++  A  
Sbjct: 121 -ANAYIADVTAPEDRAKNFGRLGATW----GVGFILGPMLGGWLGEHGLRAPFLF-AAGL 174

Query: 206 AALGPIVAPLIRSITSKLLPPDERGVA 232
            AL  +   L   +  + LPP++RG A
Sbjct: 175 TALNFLYGLL---VLPESLPPEKRGAA 198



 Score = 33.9 bits (74), Expect = 4.7
 Identities = 14/71 (19%), Positives = 35/71 (49%)

Query: 198 MMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNA 257
           ++Y+     ALG +  P ++ + S+ +   E+G     ++ + + V +F  ++ T ++ A
Sbjct: 308 VLYLSLVVGALGGLAQPAMQGLISRQVGEQEQGRVMGAITSLNSLVGVFGPLLATSVFAA 367

Query: 258 TIGTEYINSIF 268
             G  +  + F
Sbjct: 368 GQGAGFPGAAF 378


>UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -
           Leptospira borgpetersenii serovar Hardjo-bovis (strain
           JB197)
          Length = 408

 Score = 40.7 bits (91), Expect = 0.041
 Identities = 23/80 (28%), Positives = 43/80 (53%), Gaps = 1/80 (1%)

Query: 177 MGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFL 236
           +G+A++ + G+ ++A  T   MM+V      LG I  P ++ I S  +PP E+G     L
Sbjct: 291 LGLALSAL-GYALFAIATQSWMMFVFLIPYCLGGIAMPPLQGIMSSQVPPREQGELQGAL 349

Query: 237 SVMENAVAIFASIVYTQIYN 256
           + + +  AI   I+ T +++
Sbjct: 350 TSLMSVTAIVEPILMTGLFS 369



 Score = 39.5 bits (88), Expect = 0.095
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 8/94 (8%)

Query: 78  VPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALT 137
           V    A F+G  SD+ GR+ +LLA L G     + +       W     ++   + S + 
Sbjct: 63  VQFISAPFVGGLSDRYGRRPILLASLFGFTLDYLFLAFAPSIFW-----LFVGRVVSGIM 117

Query: 138 GADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
           GA    F   +AYIAD+S  + R    GIL   +
Sbjct: 118 GAS---FTTGYAYIADISPPEKRAQNFGILGAAF 148


>UniRef50_Q0CD81 Cluster: Predicted protein; n=6;
           Trichocomaceae|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 604

 Score = 40.7 bits (91), Expect = 0.041
 Identities = 27/111 (24%), Positives = 54/111 (48%), Gaps = 3/111 (2%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLY--FSIMITVN 116
           EVQ  VS F     + + ++   ++  LG  SD+ GR  ++   +LG L+   ++++   
Sbjct: 149 EVQSLVSRFQLIFNLVAGILSALVSPRLGRISDRYGRTRIIALSVLGTLFAEANVLLVAA 208

Query: 117 TMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGIL 167
              +  V  ++ +A +   L G+   + A   +Y +D +S K R++  G L
Sbjct: 209 NQEEMSVNMLLLSAII-DGLGGSFTTVLALTTSYASDCTSFKKRSVAFGYL 258



 Score = 33.5 bits (73), Expect = 6.2
 Identities = 18/76 (23%), Positives = 35/76 (46%)

Query: 184 ITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAV 243
           + GH  YA +    +M       ALG + +P+++S  +K +P +  G       ++    
Sbjct: 467 LVGHAGYALSKDSGVMIFSGVITALGGMGSPMLQSSLTKHVPHERIGQILGLKGLLHALS 526

Query: 244 AIFASIVYTQIYNATI 259
            + A  V + IY+ T+
Sbjct: 527 RVIAPTVCSLIYSVTV 542


>UniRef50_A3LRY8 Cluster: Predicted transporter ADD1; n=2;
           Saccharomycetaceae|Rep: Predicted transporter ADD1 -
           Pichia stipitis (Yeast)
          Length = 624

 Score = 40.7 bits (91), Expect = 0.041
 Identities = 34/138 (24%), Positives = 64/138 (46%), Gaps = 7/138 (5%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRK--IVLLAGLLGKLYFSIMITVN 116
           E Q+ +S       I+S ++ L  +  +G YSD+ GRK  IVL+   L     S  + + 
Sbjct: 124 EAQILMSNLQLGYSISSGIISLIASGKMGPYSDRYGRKLFIVLILFCLVLGRSSRFLIMY 183

Query: 117 TMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLP 176
             +      +I T  + + + G  L +      YI+DV     R   +GI     ++++ 
Sbjct: 184 NFDSLKFALMILT-EITANICGGILTLVTLANCYISDVVEPHQRIYSLGI----SVASMM 238

Query: 177 MGIAIAHITGHLVYAHTT 194
           +G+++  I G+ + + TT
Sbjct: 239 VGLSVGPIVGNFILSFTT 256



 Score = 34.3 bits (75), Expect = 3.6
 Identities = 12/55 (21%), Positives = 29/55 (52%)

Query: 207 ALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGT 261
           +LG +++P + S   K  P  + G  +  +++++N   +   +++  IY  T+ T
Sbjct: 480 SLGSLISPTLNSAIVKFYPESKIGELFGAIALLKNIFTLLGPVLFISIYKYTLST 534


>UniRef50_Q8DGS3 Cluster: Tlr2241 protein; n=1; Synechococcus
           elongatus|Rep: Tlr2241 protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 408

 Score = 40.3 bits (90), Expect = 0.054
 Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 13/136 (9%)

Query: 85  FLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           +LG  +D+RGRKI LL GL       +   ++  ++ P+   +        L G  +A F
Sbjct: 67  WLGPLADRRGRKITLLIGLAVAAIAPLFYILS--HNLPLLIAV------RLLHGVSIAGF 118

Query: 145 -AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGA 203
             G  A + D++  ++R   +G   + +    P+G+A+    G  +  H     +  V +
Sbjct: 119 TTGYMALVTDIAPPQHRGEIIGYTSLVH----PIGVALGPSLGSWLQMHYGHDWVFIVAS 174

Query: 204 TAAALGPIVAPLIRSI 219
           T AALG + A  +R++
Sbjct: 175 TLAALGCMAAAGVRAV 190


>UniRef50_Q20236 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 585

 Score = 40.3 bits (90), Expect = 0.054
 Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 10/161 (6%)

Query: 3   WYKYITVEPTMFFYMMAY--MITNVIEQTFY-----VFQTCHINHGYSTEICYNI-SKHA 54
           W   + VEP +F  M  +  M TN    T++     + QT       +T  C +I S + 
Sbjct: 56  WCCPVNVEPILFLVMCGFGLMTTNNSLFTYWARCVQIAQTHRELADNATYTCASIASSNG 115

Query: 55  DINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLY--FSIM 112
            +  +V+  ++    +  I   +  L ++  +G++SD+ GRK  LL  L G     F ++
Sbjct: 116 TLQDDVEKDIANTKIYLQIMGTIPTLIVSPLIGNWSDRNGRKSPLLFSLFGLFINNFILL 175

Query: 113 ITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIAD 153
               T     V Y  + +     + G   A F+   A + D
Sbjct: 176 CATLTYETVNVYYWFFISEFMLGMFGGGAATFSTSLAIVTD 216


>UniRef50_A7F7Q8 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 293

 Score = 40.3 bits (90), Expect = 0.054
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 10/159 (6%)

Query: 81  FLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTM--NDWPVEYVIYTAALPSALTG 138
           F   F GS +D  GR++VL+  LLG  + +I I V        P+E    +AA    + G
Sbjct: 120 FPGIFYGSLADHYGRRLVLVLSLLGMSFGAIWIQVVLFWSEKLPIELTWISAAF-YLVGG 178

Query: 139 ADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKM 198
             +   +  F  ++D+SS    + +   L +   ST  M +      G            
Sbjct: 179 GQVVGGSMIFVVVSDISS-DEESAQTKDLWLLRASTFSMAL------GSFAIGLAPNAIF 231

Query: 199 MYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLS 237
           + +G T  ALG    P++ S+ S L+     G+ Y  L+
Sbjct: 232 VVIGITLFALGHGFTPILLSLASTLVDSAHVGMLYNVLA 270


>UniRef50_A7EBM9 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 595

 Score = 40.3 bits (90), Expect = 0.054
 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 2/112 (1%)

Query: 168 DVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPD 227
           D T L  + + I I  I G+L +     G +       A++G + +P ++S  +K +P D
Sbjct: 446 DSTDLFVVRLSI-IFEIVGYLGFTLARSGPLFVASGIMASMGGVGSPTLQSALTKHVPHD 504

Query: 228 ERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVF 279
           + G       ++     +    ++  IY  T+GT Y  ++F    +  V  F
Sbjct: 505 QIGQLLGATGLLHALARVVCPTIFNLIYAQTVGT-YPQTVFLVLTACFVFAF 555



 Score = 39.1 bits (87), Expect = 0.13
 Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 1/138 (0%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTM 118
           EVQ  V+ F     I + +    ++  LG++SD+ GRK +L    LG     I+  +   
Sbjct: 145 EVQSLVTKFTLAITIITGIFSAVMSPLLGAWSDRNGRKKILAISSLGGFLTEIITILAGK 204

Query: 119 NDWPVEYV-IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPM 177
               V Y  +   A+   L G+  A  A   AY AD ++   R +          + + +
Sbjct: 205 YPDTVSYQWLLAGAVFDGLCGSFTAGMALTHAYAADCTAPSKRAVAFAYFHACLFAGVAI 264

Query: 178 GIAIAHITGHLVYAHTTV 195
           G  +A    HL  +  TV
Sbjct: 265 GPLLAAALFHLTQSLLTV 282


>UniRef50_Q9I4K4 Cluster: Probable major facilitator superfamily
           (MFS) transporter; n=5; Pseudomonas aeruginosa|Rep:
           Probable major facilitator superfamily (MFS) transporter
           - Pseudomonas aeruginosa
          Length = 422

 Score = 39.9 bits (89), Expect = 0.072
 Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 16/153 (10%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSAL 136
           ++ LF +  LGS SD+ GR+ VL+  +LG   F++   +  + D    ++++     + L
Sbjct: 71  LLQLFFSPVLGSLSDRFGRRPVLVLAMLG---FALSYLLLALAD--SLWMLFLGRALAGL 125

Query: 137 TGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVG 196
           TGA +A    C    AD+ +   RT   G L     + L +G+ +    G L+  H T  
Sbjct: 126 TGASVATAMAC---AADLGTHGQRTRHFGWL----YAGLALGMILGPALGGLLAVHGTTL 178

Query: 197 KMMYVGATAAALGPIVAPLIRSITSKLLPPDER 229
            ++ + A    L  ++A L    T   LPP  R
Sbjct: 179 PLL-LAAGLCLLNALLAGLFLEET---LPPTRR 207


>UniRef50_Q8F6D6 Cluster: Tetracycline resistance protein, class A;
           n=4; Bacteria|Rep: Tetracycline resistance protein,
           class A - Leptospira interrogans
          Length = 409

 Score = 39.9 bits (89), Expect = 0.072
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 8/109 (7%)

Query: 78  VPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALT 137
           V    A F+G  SD+ GR+ VLLA L G     + +       W     ++   + + + 
Sbjct: 63  VQFVCAPFVGGLSDRYGRRPVLLASLFGFTLDYLFLAFAPSIFW-----LFVGRVLAGIM 117

Query: 138 GADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           GA    F   +AYIAD+S  + R    GIL   +     +G  I  I G
Sbjct: 118 GAS---FTTGYAYIADISPPEKRAQNFGILGAAFGFGFIIGPVIGGILG 163



 Score = 39.5 bits (88), Expect = 0.095
 Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 1/80 (1%)

Query: 177 MGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFL 236
           +G+A++ + G+ ++A  T   MM+V      LG I  P ++ I S  +P +E+G     L
Sbjct: 291 LGLALSGL-GYALFALATQSWMMFVFLIPYCLGGIAMPPLQGIMSSQVPSNEQGELQGAL 349

Query: 237 SVMENAVAIFASIVYTQIYN 256
           + + +  AI   I+ T +++
Sbjct: 350 TSLMSVTAILGPILMTGLFS 369


>UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1;
           Pirellula sp.|Rep: Tetracycline-efflux transporter -
           Rhodopirellula baltica
          Length = 500

 Score = 39.9 bits (89), Expect = 0.072
 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)

Query: 72  GIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAA 131
           G    ++  F A  LG+ SD+ GR+ V+LA L G     I+  +     W     ++   
Sbjct: 108 GATYSLMQFFFAPVLGALSDRFGRRPVILASLFGLGVDFIVTGLAPTVGW-----LFVGR 162

Query: 132 LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           + + + GA    F+   AYIADVS+ + R    G++ + +     +G A+  + G
Sbjct: 163 IVAGVMGAS---FSTANAYIADVSTQETRARNFGLVGMMFGLGFIIGPALGGVLG 214


>UniRef50_Q9Z479 Cluster: Drug efflux protein TetA; n=3;
           Proteobacteria|Rep: Drug efflux protein TetA -
           Agrobacterium tumefaciens
          Length = 394

 Score = 39.9 bits (89), Expect = 0.072
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 12/106 (11%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LG+ SD+ GR+ VLL  L G L   +++  +     P+ +V+      + +T A++A+ +
Sbjct: 61  LGALSDRFGRRPVLLLSLAGTLLDYLVMAFS-----PLGWVLVVGRAMAGITSANMAVAS 115

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYA 191
              AYI D++  + R  R G    T  + + +G  I  + G ++ A
Sbjct: 116 ---AYITDITPAEQRAQRFG----TVGAVMSLGFIIGPVIGGVIGA 154


>UniRef50_Q0U5D5 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 594

 Score = 39.9 bits (89), Expect = 0.072
 Identities = 21/95 (22%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 186 GHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAI 245
           G+L +     G++  +    AA+G I  P + +  +K +PPD+ G       ++     +
Sbjct: 475 GYLGFILARKGEIFALSGALAAMGGIGNPTLGAALTKHVPPDKVGQLLGATGLLHAVARV 534

Query: 246 FASIVYTQIYNATIGTEYINSIFYFTISTQVIVFL 280
               ++  IY+AT+G+ +  ++F    +T  + F+
Sbjct: 535 IGPTIFNGIYSATVGS-FRQTVFVTLCATFGLAFV 568



 Score = 38.7 bits (86), Expect = 0.17
 Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 11/154 (7%)

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIM--IT 114
           N  V    S F  +  + S ++    +  LG+ SD+ GRK  L+   +G L+  ++  + 
Sbjct: 156 NDTVSSRSSLFLLYGSLCSGILSAITSPKLGALSDRHGRKKFLIFNTIGTLFAEVLTILA 215

Query: 115 VNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
               + + V +++    +   +TG+ +   A   +Y +D +S + RT+            
Sbjct: 216 AKYPDIFHVNWILVGYCI-EGVTGSFIVGMAIAHSYASDCTSPQKRTVAFSYFHACLFGG 274

Query: 175 LPMGIAIAHITGHLVYAHTTVGKMMYVGATAAAL 208
           + +G A   ++G+++ A     +  YVG T A L
Sbjct: 275 IAIGPA---LSGYVISA-----REKYVGHTEAVL 300


>UniRef50_Q21M22 Cluster: Major facilitator superfamily MFS_1; n=1;
           Saccharophagus degradans 2-40|Rep: Major facilitator
           superfamily MFS_1 - Saccharophagus degradans (strain
           2-40 / ATCC 43961 / DSM 17024)
          Length = 471

 Score = 39.1 bits (87), Expect = 0.13
 Identities = 42/141 (29%), Positives = 70/141 (49%), Gaps = 16/141 (11%)

Query: 72  GIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIY 128
           G+A  +  L  A F   LG  SD  GRK V++AGLL  ++ +  +   T     VE++I 
Sbjct: 68  GLALGIYGLTQAVFQIPLGLLSDFIGRKPVIIAGLL--VFCAGSVLAGTAES--VEWLI- 122

Query: 129 TAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
              +  AL G+  AI +   A +AD++S +NRT  +  +     +++ +  ++A I G  
Sbjct: 123 ---IGRALQGSG-AIASTIMAMVADLTSEQNRTKAMAAIG----ASIGLSFSLAMILGPT 174

Query: 189 VYAHTTVGKMMYVGATAAALG 209
           V A   +  + Y  A  A +G
Sbjct: 175 VGAFGGLSVVFYFSAVLALIG 195


>UniRef50_Q192M5 Cluster: Major facilitator superfamily MFS_1; n=2;
           Desulfitobacterium hafniense|Rep: Major facilitator
           superfamily MFS_1 - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 392

 Score = 39.1 bits (87), Expect = 0.13
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 74  ASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALP 133
           A  ++  F A F G  SD+ GR+ VLL GL G  Y           + P+  +I   AL 
Sbjct: 50  AYSIMQFFFAPFWGRLSDRIGRRPVLLIGLSG--YGITFFLYGMAGNLPL--LIAFRALS 105

Query: 134 SALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGH 187
             ++ A L       AY+AD++   +R+  +G+L       +  G A+    GH
Sbjct: 106 GVVSSATLPT---AMAYMADITEGADRSKSMGMLGAAMGLGMVFGPALGGFLGH 156


>UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1;
           Picrophilus torridus|Rep: Tetracycline resistance
           protein - Picrophilus torridus
          Length = 384

 Score = 39.1 bits (87), Expect = 0.13
 Identities = 25/83 (30%), Positives = 47/83 (56%), Gaps = 8/83 (9%)

Query: 85  FLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           +LG  SD+ GRK VL+ GL G++   ++  ++     PV  ++Y   +  A+TGA     
Sbjct: 57  YLGRLSDRIGRKNVLVLGLSGEIAGYLIFGLS-----PVLSLLY---IGRAITGATSGNL 108

Query: 145 AGCFAYIADVSSVKNRTLRVGIL 167
              +++++D +S  NRT  +G++
Sbjct: 109 PVIYSFVSDKTSSDNRTRAIGMI 131


>UniRef50_Q0HZC0 Cluster: Major facilitator superfamily MFS_1; n=12;
           Alteromonadales|Rep: Major facilitator superfamily MFS_1
           - Shewanella sp. (strain MR-7)
          Length = 455

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 16/150 (10%)

Query: 70  WNGIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYV 126
           W GIA     L  A     +G  SDK GRK V+LAGL   + F+I   +    D      
Sbjct: 49  WVGIAIGAYGLTQAVLQIPMGILSDKYGRKPVILAGL---VLFAIGSLIAANAD-----T 100

Query: 127 IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           IY      A+ G   AI A   A  AD++  + RT  + I+ +     +    A++ + G
Sbjct: 101 IYGVVFGRAVQGMG-AIAAAVLALAADLTRDEQRTKVMAIIGM----CIGGSFALSLLVG 155

Query: 187 HLVYAHTTVGKMMYVGATAAALGPIVAPLI 216
            +V  H  +  +  + A  A LG ++  L+
Sbjct: 156 PIVAQHLGLSGLFLLTAGLAVLGMLIVQLL 185


>UniRef50_Q0AX92 Cluster: Multidrug-efflux transporter; n=1;
           Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
           Multidrug-efflux transporter - Syntrophomonas wolfei
           subsp. wolfei (strain Goettingen)
          Length = 370

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 9/108 (8%)

Query: 85  FLGSYSDKRGRKIVLLAGLLG-KLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAI 143
           F GSYSD+ GRK VLL G+ G  L F I    N++      +V++ A +         A 
Sbjct: 35  FWGSYSDRVGRKPVLLVGMFGFTLTFFIFALANSL------WVLFVARIAGG--ALSCAT 86

Query: 144 FAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYA 191
                A + D SS + R   +G++  +    +  G AI     H+  A
Sbjct: 87  VPTAMAVMGDTSSPEKRGASMGMVGASMGMGMIFGPAIGSGLAHISLA 134


>UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=4;
           Chloroflexaceae|Rep: Major facilitator superfamily MFS_1
           - Roseiflexus sp. RS-1
          Length = 428

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 86  LGSYSDKRGRKIVLLAGLLGK-LYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           LG+ SD+ GR+ +LL  +LG  L + +      ++   VE V+    +   L+G   A  
Sbjct: 69  LGALSDRYGRRPILLISVLGSGLSYVLFGFAEYLSFLGVETVLAILFIGRMLSGITGASI 128

Query: 145 AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           +   AYIAD ++ + RT  +G++   +     +G A+
Sbjct: 129 STAQAYIADTTTPEERTKGMGMIGAAFGLGFMLGPAL 165


>UniRef50_Q12IY6 Cluster: Major facilitator superfamily MFS_1; n=11;
           Alteromonadales|Rep: Major facilitator superfamily MFS_1
           - Shewanella denitrificans (strain OS217 / ATCC BAA-1090
           / DSM 15013)
          Length = 455

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 16/143 (11%)

Query: 70  WNGIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYV 126
           W GIA     L  A     +G  SDK GRK ++L GL   + F++   +  M+D      
Sbjct: 49  WVGIAIGAYGLTQALLQIPMGILSDKYGRKPIILIGL---VLFAVGSIIAAMSDH----- 100

Query: 127 IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           IY      A+ G   AI A   A  AD++  + RT  + I+ +     + +  A++ + G
Sbjct: 101 IYWVVFGRAVQGMG-AIAAAVLALAADLTRDEQRTKVMAIIGM----CIGLSFALSLLAG 155

Query: 187 HLVYAHTTVGKMMYVGATAAALG 209
            LV  +  +  + ++ A  A LG
Sbjct: 156 PLVAQYLGLSGIFWLTAVLAVLG 178


>UniRef50_Q04HD0 Cluster: Permease of the major facilitator
           superfamily; n=2; Oenococcus oeni|Rep: Permease of the
           major facilitator superfamily - Oenococcus oeni (strain
           BAA-331 / PSU-1)
          Length = 395

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 4/63 (6%)

Query: 84  FFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEY--VIYTAALPSALTGADL 141
           + LGS+SD+ GRK VL AG+L  L F IM     + D+ + Y  +I      SAL  +  
Sbjct: 52  YILGSFSDRIGRKPVLYAGMLSYLLFFIMTPF--IKDFHLAYLLIILAGVANSALDASTY 109

Query: 142 AIF 144
            IF
Sbjct: 110 PIF 112


>UniRef50_Q6BW37 Cluster: Similar to CA5023|IPF7547 Candida albicans
           IPF7547 of unknown function; n=2;
           Saccharomycetaceae|Rep: Similar to CA5023|IPF7547
           Candida albicans IPF7547 of unknown function -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 623

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 42/177 (23%), Positives = 81/177 (45%), Gaps = 14/177 (7%)

Query: 13  MFFYMMAYMITNVIEQTFYVFQTCHINHGYSTEICYNISKHADINKEVQVTVSTFHQWNG 72
           +FF+ +A+ I +   +       C+   G S E      K   I    Q+ VS  +    
Sbjct: 78  LFFFAIAFSIGDSTRRMITFKLACNYLAGMSKE-----DKCDPIG--TQLLVSNLYLTYS 130

Query: 73  IASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWP-VEYVIYTAA 131
           I S VV +F    +G+ SD+ GRK+  +  ++     + +     M+++  +++ +  A 
Sbjct: 131 ILSAVVMMFAQGKIGTLSDQYGRKLFFIL-IISMFLLARIFKFYVMHNYEYLQFGLMVAT 189

Query: 132 -LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGH 187
            + S LTG  +++ +    YIADV     R   +G+     ++ L +G++I  I G+
Sbjct: 190 EIASNLTGGMISLISLTNCYIADVVEPHQRIYSLGL----GMAFLFVGLSIGPILGN 242


>UniRef50_A7TGR1 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 568

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 4/146 (2%)

Query: 42  YSTEICYNISKHADINK-EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGR-KIVL 99
           Y  E     +K A+ +K EVQ   S       I S ++   L+   G+ SD+ GR ++  
Sbjct: 116 YGDEDISREAKIANCDKQEVQRITSEITSLTIIISGILNTLLSGKWGALSDRIGRVRVFA 175

Query: 100 LAGLLGKLYFSIMITVNTMNDWPVEYVIYTAA-LPSALTGADLAIFAGCFAYIADVSSVK 158
             G++ KL  +I+     +   P    +  A  +  +L G   AI +   +YI DV+  +
Sbjct: 176 FVGII-KLIGTIIQIYTVLPSTPYSKTLLIAPEVVQSLGGGIFAIVSNSNSYITDVAEPE 234

Query: 159 NRTLRVGILDVTYLSTLPMGIAIAHI 184
            RT+ + ++  T   ++ +G  ++ I
Sbjct: 235 YRTMSISLMMSTLYGSMGLGPILSSI 260


>UniRef50_A6SA36 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 528

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 5/129 (3%)

Query: 57  NKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVN 116
           N  +Q  ++    W+G  + +  L L+   G  +DK GRK VL   L+G     I + V 
Sbjct: 100 NDVIQGKLAMLRGWDGTLACIPGLILSVPFGILADKIGRKTVLFMSLIGLSLGLIWVQVI 159

Query: 117 TMND--WPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNR-TLRVGILDVTYLS 173
              D  + V + I++A L + + G         +  IADV + + R T+   I+  + ++
Sbjct: 160 CYFDTFFDVRW-IWSANLLALIGGGSAVTKTMYYTIIADVVAEEQRATVFFQIVSASLIA 218

Query: 174 TLPMGIAIA 182
           TL  G+ +A
Sbjct: 219 TL-AGVPLA 226


>UniRef50_Q6KZX2 Cluster: Putative multidrug resistance protein;
           n=2; Thermoplasmatales|Rep: Putative multidrug
           resistance protein - Picrophilus torridus
          Length = 410

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 80  LFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGA 139
           +FL FFLG+  D+ G   +L  G L  L   +++ V+T N + +      A +     G 
Sbjct: 60  VFLTFFLGTAGDRIGYSRILFIGELFPLVGMLILAVST-NIYLIALGAIIAGITGGAGGM 118

Query: 140 DLAIFAGCFAYIADVSSVKN-RTLRVGILDVT 170
             A   G  AY+A    V N R  R+ +L+ T
Sbjct: 119 RGAFSPGMTAYVASSYDVDNLRVQRLSLLNAT 150


>UniRef50_Q0W242 Cluster: Putative permease; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Putative permease -
           Uncultured methanogenic archaeon RC-I
          Length = 409

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 7/91 (7%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSAL 136
           V+ L    FLG  SD+ GRK V L GL G    S +I       W    +++ A +   +
Sbjct: 55  VMQLIFTPFLGELSDRVGRKPVFLIGLFG-YGVSFLIYGFATQLW----MLFAARMIGGI 109

Query: 137 TGADLAIFAGCFAYIADVSSVKNRTLRVGIL 167
                 I+    AYIAD++S K R   +G+L
Sbjct: 110 LSG--GIYPASLAYIADITSHKERGRIMGML 138


>UniRef50_Q65F99 Cluster: Blt; n=2; Bacillus|Rep: Blt - Bacillus
           licheniformis (strain DSM 13 / ATCC 14580)
          Length = 398

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 14/144 (9%)

Query: 74  ASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALP 133
           AS +  L  +   G  +DK GR+ +++ G+ G    S ++       W    +++ + L 
Sbjct: 48  ASGITQLLFSPVAGEMTDKYGRRKMIILGI-GAFAVSQLLFALASQMW----LLFVSRL- 101

Query: 134 SALTGADLAIFA-GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAH 192
             L GA  A      FAYIAD++S K+R+  +G++     + + +G  I    G  + A 
Sbjct: 102 --LGGAGAAFLVPAMFAYIADITSEKDRSKGMGLIS----AAMSLGFVIGPGAGGYLAAF 155

Query: 193 TTVGKMMYVGATAAALGPIVAPLI 216
                  YV A  A L  +++ L+
Sbjct: 156 GLTFP-FYVSAGLAGLATVLSLLV 178


>UniRef50_Q56RY7 Cluster: TetA; n=4; Acinetobacter|Rep: TetA -
           Acinetobacter sp. LUH5605
          Length = 395

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 8/110 (7%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSAL 136
           ++    A  LG+ SD+ GR+ VL+  + G     +++       W     +Y   + + +
Sbjct: 52  LMQFIFAPILGALSDRFGRRPVLIISIAGATADYLLMAAAPSLLW-----LYIGRIFAGI 106

Query: 137 TGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           TGA++A+     AY++D++    R  R G+L   +      G  I  + G
Sbjct: 107 TGANMAV---ATAYVSDITPAHERAKRFGLLGAVFGIGFIAGPVIGGVLG 153


>UniRef50_Q21E97 Cluster: Major facilitator superfamily MFS_1; n=1;
           Saccharophagus degradans 2-40|Rep: Major facilitator
           superfamily MFS_1 - Saccharophagus degradans (strain
           2-40 / ATCC 43961 / DSM 17024)
          Length = 413

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 8/111 (7%)

Query: 81  FLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGAD 140
           F A F+G   D  GR+ VL+  LLG     IM  V         +V+  + L    T  +
Sbjct: 56  FAAPFMGRLGDSYGRRPVLIISLLGSCIGYIMFGVG-----GALWVLLISRLLDGFTAGN 110

Query: 141 LAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYA 191
            ++ AG  AYIADVS+ + R     +  + +   L  G A+  + G +  A
Sbjct: 111 QSV-AG--AYIADVSTPETRAKNFTLFGMAWGVALVAGPALGAVFGEISLA 158


>UniRef50_A1RW34 Cluster: Major facilitator superfamily MFS_1; n=1;
           Thermofilum pendens Hrk 5|Rep: Major facilitator
           superfamily MFS_1 - Thermofilum pendens (strain Hrk 5)
          Length = 428

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 9/117 (7%)

Query: 164 VGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKL 223
           VG + +  + T P      +    LV +   VG MM+             P I ++ S++
Sbjct: 301 VGYVSMMLMVTYPYPYGSTNFKDLLVPSALAVGGMMFT--------TFAYPNINTVLSEV 352

Query: 224 LPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFL 280
           + P+ RG  +A  SV+ N        VYT +  A  G  Y + +   T +   IV L
Sbjct: 353 VVPEHRGTVFAVYSVLNNLGWTLGPTVYTLLLKAFSGV-YADQVSAMTAAASTIVSL 408


>UniRef50_UPI00002053B2 Cluster: PREDICTED: hippocampus abundant
           transcript 1 isoform 1; n=3; Eutheria|Rep: PREDICTED:
           hippocampus abundant transcript 1 isoform 1 - Pan
           troglodytes
          Length = 466

 Score = 37.5 bits (83), Expect = 0.38
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 21/161 (13%)

Query: 71  NGIASHVVPL--FL-AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVI 127
           NG+   V  L  FL A  +G+ SD  GRK  LL   L   +    I +  ++ W      
Sbjct: 74  NGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLL---LTVFFTCAPIPLMKISPW-----W 125

Query: 128 YTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGH 187
           Y A +  +++G     F+  FAY+AD++    R++  G++  T+ ++L    AI    G 
Sbjct: 126 YFAVI--SVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGR 183

Query: 188 LVYAHTTVGKMMYVGATAAALGPIVAPLI---RSITSKLLP 225
            VY  +    ++ V ATA AL  I   L+    S+  K+ P
Sbjct: 184 -VYGDS----LVVVLATAIALLDICFILVAVPESLPEKMRP 219


>UniRef50_Q93S11 Cluster: Putative integral membrane transport
           protein; n=1; Streptomyces coelicolor|Rep: Putative
           integral membrane transport protein - Streptomyces
           coelicolor
          Length = 543

 Score = 37.5 bits (83), Expect = 0.38
 Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 10/131 (7%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           +G+  D+ GR+ +L+ G LG +  S++   +T      E +I   AL   L  A  A+  
Sbjct: 74  MGTLGDRIGRRRLLILGSLGVIAASVLAAYSTSP----EMLIVARAL---LGVAGAAVLP 126

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATA 205
              + I  +   K+   R   +  T+++ L +GIAI  + G ++  H   G +  +G   
Sbjct: 127 STLSLI--IHMFKDDRQRATAI-ATWVTALSVGIAIGPVIGGVLLEHWWWGSVFLMGVPV 183

Query: 206 AALGPIVAPLI 216
             +  ++AP++
Sbjct: 184 MLVPVLLAPVL 194


>UniRef50_Q5WGK5 Cluster: Major facilitator (MFS) superfamily
           multidrug resistance protein; n=1; Bacillus clausii
           KSM-K16|Rep: Major facilitator (MFS) superfamily
           multidrug resistance protein - Bacillus clausii (strain
           KSM-K16)
          Length = 403

 Score = 37.5 bits (83), Expect = 0.38
 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 16/150 (10%)

Query: 82  LAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADL 141
           +A + GS+SD+ GRK +++AGLL      ++  + T        +++ + L   L G  +
Sbjct: 61  VAPYAGSWSDRYGRKWIIVAGLLLFAVSELLFGLATN-----AVLLFISRL---LGGVSV 112

Query: 142 A-IFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMY 200
           A I     AY+ D+++ ++R + +G ++    +   +G AI    G LV     V    +
Sbjct: 113 AFIMPAVMAYVVDITTEEDRGMGMGWINAAISTGFIIGPAIG---GFLVEYGMRV--PFF 167

Query: 201 VGATAAALGPIVAPLI--RSITSKLLPPDE 228
             A AAAL  +V+  I   S+    LP  E
Sbjct: 168 AAAGAAALSAVVSMSILPESLDKNKLPAPE 197


>UniRef50_A4A657 Cluster: Major facilitator family transporter; n=1;
           Congregibacter litoralis KT71|Rep: Major facilitator
           family transporter - Congregibacter litoralis KT71
          Length = 395

 Score = 37.5 bits (83), Expect = 0.38
 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 13/130 (10%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LG  SDK GRK V+L GL   L+    +        P+       A+  AL GA  AI  
Sbjct: 63  LGWLSDKIGRKPVILGGL--ALFVLGSVVAALAESVPM------IAVGRALQGAG-AISG 113

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATA 205
              A  AD++S + RT  + ++ +    ++ +  A+A I G L+ A   +  + ++ A  
Sbjct: 114 SVMALAADLTSEEQRTKAMAVIGI----SIGLSFALALICGPLLAAWGGLAAVFWMTAAL 169

Query: 206 AALGPIVAPL 215
           A LG  +  L
Sbjct: 170 AVLGMAIVLL 179


>UniRef50_Q0W1K3 Cluster: Putative permease; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Putative permease -
           Uncultured methanogenic archaeon RC-I
          Length = 410

 Score = 37.5 bits (83), Expect = 0.38
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 7/98 (7%)

Query: 87  GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG 146
           G  SD+ GRK V+L GL G    S ++T  +   W    +++ A +   L  A   I+  
Sbjct: 62  GKLSDRIGRKPVMLIGLFG-FALSFILTGFSTQLW----MLFAAQILGGLLSA--GIWPA 114

Query: 147 CFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHI 184
             AY+ D+SS ++R   +G +       + +G AI+ I
Sbjct: 115 VLAYVTDISSPEDRGKLMGFMGAASGLGIIVGPAISSI 152


>UniRef50_UPI0000EBDD0E Cluster: PREDICTED: hypothetical protein
           LOC511097; n=1; Bos taurus|Rep: PREDICTED: hypothetical
           protein LOC511097 - Bos taurus
          Length = 459

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 35  TCHINHGYSTEICYNISKHAD---------INKEVQVTVSTFHQWNGIASHVVPLFLAFF 85
           T ++ H +S ++ YN ++H D         I +EV+   S +  +  +   +V LF +  
Sbjct: 44  TQYLWHRFSADLGYNGTRHRDSCSNHSVDPIAQEVETLTSHWTLYMNVGGFLVGLFSSTL 103

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIM 112
           LG++SD  GR+ +L+   LG L  +++
Sbjct: 104 LGAWSDCVGRRPLLVLASLGLLLQTVL 130


>UniRef50_Q89MY8 Cluster: Tetracycline resistance protein; n=7;
           Bradyrhizobiaceae|Rep: Tetracycline resistance protein -
           Bradyrhizobium japonicum
          Length = 462

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 18/89 (20%), Positives = 45/89 (50%), Gaps = 1/89 (1%)

Query: 173 STLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVA 232
           +TL +G+    I G +++     G + ++G    +L  I    ++S+ ++L+ PD++G  
Sbjct: 333 NTLLLGLCCGAI-GFVIFGAAPTGPLFWIGIPVMSLWGISGAAMQSLMTRLVAPDQQGQL 391

Query: 233 YAFLSVMENAVAIFASIVYTQIYNATIGT 261
               + +++   +    ++T  ++  IGT
Sbjct: 392 QGATASVQSVSQLVGPFLFTLTFSYFIGT 420


>UniRef50_A3XKG1 Cluster: Multidrug-efflux transporter; n=2;
           Flavobacteriaceae|Rep: Multidrug-efflux transporter -
           Leeuwenhoekiella blandensis MED217
          Length = 405

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 16/154 (10%)

Query: 72  GIASHVVPLFLAFFL---GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIY 128
           G+ + + PLF   F+   G  SD+ GRK V++ GL+G +   ++  + T        ++Y
Sbjct: 54  GLLTSIYPLFQLIFVIVWGKLSDRYGRKPVIIIGLIGFVIMQLLTGLATSLT-----MLY 108

Query: 129 TAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG-- 186
            A +   +  + +   +   AY++D++S K RT  +    V   S +  G  I       
Sbjct: 109 IARIFGGVFTSSVIPVSN--AYLSDITSEKRRTKIMAWSGVAISSGVIFGPVIGGFLSQS 166

Query: 187 --HLVYA--HTTVGKMMYVGATAAALGPIVAPLI 216
             H  YA     +G+       AA LG IV  ++
Sbjct: 167 DLHFEYAIGQLHLGRFSTPFLFAALLGSIVLVIV 200


>UniRef50_A5DS14 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 623

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 32/123 (26%), Positives = 63/123 (51%), Gaps = 5/123 (4%)

Query: 47  CYNISKHADINKEV-QVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLG 105
           C ++  +   + E+ Q+ + +++Q + +   ++ L LA  +  YSD  GRK  L++  L 
Sbjct: 129 CNSVEVNGHCSPELTQILIGSYNQASMVGMTLISL-LAVSMFGYSDIIGRKPFLVS-TLA 186

Query: 106 KLYFSIMITVNTMNDWPV-EYV-IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLR 163
               S M+    M  +   ++V +  AA  SA++G  + I +   AYI+DV  ++ RT  
Sbjct: 187 LFTMSRMVEFYLMTHYDTFKFVPMIVAAYVSAISGGFVIIGSIINAYISDVCPIEGRTYA 246

Query: 164 VGI 166
           + +
Sbjct: 247 LAL 249


>UniRef50_A4RKE7 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 606

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 7/127 (5%)

Query: 60  VQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLL----AGLLGKLYFSIMITV 115
           VQ   +TF     + + ++  F    +GS SD+ GRK +L+     G++G+L   +++ V
Sbjct: 135 VQREAATFMMTMNLITGLLSAFTVPKIGSLSDRYGRKRLLVVASAGGIIGELV--VILAV 192

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
                  + +++  AAL   L G+  A      +Y++D +  + R + +G L     + L
Sbjct: 193 KFPETVHLNWLLVAAAL-DGLGGSFTAASVVGHSYVSDCTPPRKRGVAIGYLHSALYAGL 251

Query: 176 PMGIAIA 182
             G  +A
Sbjct: 252 AFGPVLA 258



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 5/106 (4%)

Query: 178 GIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLS 237
           G  ++ I G   Y       +  + A  AA+G +V+P  +S  +K +P D+ G     + 
Sbjct: 459 GAILSDILGVTGYILVRTPALFLLSAVVAAMGGLVSPTTQSALTKHVPADQVGSLLGAIG 518

Query: 238 VMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSAL 283
           ++     +   +  + +Y AT+  E      Y  +   V++F+ AL
Sbjct: 519 LLHALARVLFPLAISGLYAATV--ESFPQAVYVLL---VVIFVLAL 559


>UniRef50_Q01NN6 Cluster: Multi-sensor signal transduction histidine
           kinase precursor; n=1; Solibacter usitatus
           Ellin6076|Rep: Multi-sensor signal transduction
           histidine kinase precursor - Solibacter usitatus (strain
           Ellin6076)
          Length = 822

 Score = 36.7 bits (81), Expect = 0.67
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 8/100 (8%)

Query: 160 RTLRVGILDVTYL----STLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGP-IVAP 214
           R LR G + + Y+    S  P+  ++A +    V      GK + +GATAA+LG  I +P
Sbjct: 233 RVLRGGRMSIDYIGPAGSFNPVTYSLADVVAGRVPPEKFRGKFVLIGATAASLGDRITSP 292

Query: 215 LIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQI 254
            +R   ++    D+ G     + V+ N++ +  S  Y  +
Sbjct: 293 FVRYTDAR---ADQHGALMPGVEVLANSINVILSGRYYSV 329


>UniRef50_A3VN57 Cluster: Permease; n=1; Parvularcula bermudensis
           HTCC2503|Rep: Permease - Parvularcula bermudensis
           HTCC2503
          Length = 441

 Score = 36.7 bits (81), Expect = 0.67
 Identities = 40/140 (28%), Positives = 62/140 (44%), Gaps = 19/140 (13%)

Query: 86  LGSYSDKRGRKIVLLAGLLGK-LYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           +G+ SD+ GR+ V+L  L    + F +M  V T   W V        L   L+GA  A F
Sbjct: 68  IGALSDQYGRRPVILVSLFFYGIDFLLMAFVPTFG-WLV--------LGRLLSGATAATF 118

Query: 145 AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMY---- 200
           +   A+IADVS  + R    GI+   +     +G  I  + G L  A+     +++    
Sbjct: 119 STAGAFIADVSPPEKRAQNFGIIGAAF----GLGFIIGPVLGGLAAAYGPSLAILFPSDS 174

Query: 201 -VGATAAALGPIVAPLIRSI 219
            V +   A GP    L+ S+
Sbjct: 175 GVASALTAFGPRYPFLLASV 194



 Score = 33.9 bits (74), Expect = 4.7
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%)

Query: 180 AIAHITGHLVYAH-TTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSV 238
           ++A     L YA  T  G  +YV  T  ALG  + P +++  +K    D +G     ++ 
Sbjct: 311 SVAMALSTLGYAFFTPAGPWVYVWITVGALGGFMMPGMQAKMTKATAEDAQGELQGAIAS 370

Query: 239 MENAVAIFASIVYTQIYNA 257
           + +    F+ ++ TQI+ A
Sbjct: 371 LSSITMAFSPLMMTQIFAA 389


>UniRef50_A4S4A5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 194

 Score = 36.7 bits (81), Expect = 0.67
 Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 6/95 (6%)

Query: 118 MNDWPVEYVIYTAALPSALT---GADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLST 174
           +N + + Y+++ +A+ S       + LAIF    A    V SV++  L++G  ++++  T
Sbjct: 61  LNYFRINYLVFASAVLSLFVLFHPSSLAIFGSVAAAWVYVFSVRSEPLKIGDRELSHRET 120

Query: 175 LPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALG 209
           L MG++   ++  +++  T+ G +++ G   A LG
Sbjct: 121 L-MGMSA--LSAFVIFMLTSAGTVLFSGLGVALLG 152


>UniRef50_Q4J8C3 Cluster: Conserved membrane protein; n=2;
           Sulfolobus|Rep: Conserved membrane protein - Sulfolobus
           acidocaldarius
          Length = 470

 Score = 36.7 bits (81), Expect = 0.67
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 10/162 (6%)

Query: 123 VEYVIYTAALPSALTGADLAIFAGCF---AYIADVSSVKNRTLRVGILDVTYLSTL-PMG 178
           V+  I   ALP+  T     ++   +   AY+  ++ +  +  R+G  D+   S +  MG
Sbjct: 19  VDTTIVLLALPTITTDLHTDLYTSIWVLLAYLLVLAILSTQAGRIG--DIVGRSRIYNMG 76

Query: 179 IAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSV 238
             +  +   L      +  ++      AA G ++A    +I + +LPP+ RG AY   S+
Sbjct: 77  FLLFTLASGLCGISPNIEFLIGFRILQAAGGAMLASNSGAIVADILPPNRRGGAYGLTSL 136

Query: 239 MENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFL 280
             N  A+   I+   +    +G  Y   IFY  +   +I  +
Sbjct: 137 GWNVGALL-GIILGGVLTTFLGWRY---IFYINVPIGIIAVI 174


>UniRef50_Q2SB41 Cluster: Putative uncharacterized protein; n=1;
           Hahella chejuensis KCTC 2396|Rep: Putative
           uncharacterized protein - Hahella chejuensis (strain
           KCTC 2396)
          Length = 569

 Score = 36.3 bits (80), Expect = 0.88
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 49  NISKHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLY 108
           N+  +A + KEV +   T+    G  SH  PL +AF+L  Y+ + G++ VL  G++    
Sbjct: 487 NLPDYAKLRKEVTLDTVTYSATLGQLSHT-PLTVAFYLEPYTQRFGKQGVLTKGVVISPD 545

Query: 109 FS---IMITVNTMNDWPVE 124
           F    +    N  N +PVE
Sbjct: 546 FPSKYLYGHFNVFNRYPVE 564


>UniRef50_Q1ARX5 Cluster: Major facilitator superfamily MFS_1; n=3;
           Bacteria|Rep: Major facilitator superfamily MFS_1 -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 418

 Score = 36.3 bits (80), Expect = 0.88
 Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 10/137 (7%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSAL 136
           VV  F   F G  +D+ GRK VL+AG +  +    MI +     W V   +    +   L
Sbjct: 72  VVKAFSNLFAGGLADRFGRKRVLVAGWIIGVPVPFMIMLAPSWGWVVAANV-LLGMNQGL 130

Query: 137 TGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVG 196
             +   I         D+   + R L VG+ +  +   L +G A A +TG+L   +    
Sbjct: 131 AWSTTVIMK------IDLVGPRGRGLAVGLNE--FAGYLAVG-ATAWLTGYLASVYGLRP 181

Query: 197 KMMYVGATAAALGPIVA 213
           +  Y+GA  A LG +++
Sbjct: 182 EPFYLGAAYALLGLLIS 198


>UniRef50_A7HKI1 Cluster: Major facilitator superfamily MFS_1; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: Major facilitator
           superfamily MFS_1 - Fervidobacterium nodosum Rt17-B1
          Length = 407

 Score = 36.3 bits (80), Expect = 0.88
 Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 11/113 (9%)

Query: 72  GIASHVVPL---FLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIY 128
           G  S + PL   F +  +G  SDK GRKI LL   +G  + S+++    +       +I+
Sbjct: 54  GFLSMIYPLGQIFASPLIGRMSDKFGRKIALLLS-VGGTFLSLLL----LGFAKSLTLIF 108

Query: 129 TAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
            + L   LTG ++ +     +YI+D +  K+R   +G++   +     +G AI
Sbjct: 109 ISRLLDGLTGGNITV---AQSYISDFTDKKSRAKSLGLIGAAFGLGFILGPAI 158


>UniRef50_Q97C83 Cluster: Multidrug resistance protein; n=3;
           Thermoplasma|Rep: Multidrug resistance protein -
           Thermoplasma volcanium
          Length = 427

 Score = 36.3 bits (80), Expect = 0.88
 Identities = 16/44 (36%), Positives = 27/44 (61%)

Query: 211 IVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQI 254
           IV+P+  SI +KL PPD+RG  Y  +S+    ++  A ++ T +
Sbjct: 338 IVSPVSNSIVAKLAPPDKRGEYYGAMSLFVGFISPIAPVLGTSL 381


>UniRef50_Q4RG87 Cluster: Chromosome 12 SCAF15104, whole genome
           shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
           Chromosome 12 SCAF15104, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 576

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 15/52 (28%), Positives = 27/52 (51%)

Query: 186 GHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLS 237
           G ++ A   V +MM+     AA+  I  P + ++ S    PD++GVA   ++
Sbjct: 457 GPVLMAAVVVSRMMWAAGAVAAMSSITFPAVSALVSHCASPDQQGVAQGMIT 508


>UniRef50_Q8DMH7 Cluster: Multidrug-efflux transporter; n=2;
           Cyanobacteria|Rep: Multidrug-efflux transporter -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 403

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 8/92 (8%)

Query: 80  LFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGA 139
           L  A  LG+ SD  GR+ VLL  + G     I+  V T       ++++ + +   LTG 
Sbjct: 56  LIAAPLLGALSDHWGRRPVLLICIAGTAVSYILFAVAT-----APWLLFVSRIIDGLTG- 109

Query: 140 DLAIFAGCFAYIADVSSVKNRTLRVGILDVTY 171
              + +   AYIAD S+  NR    G+    +
Sbjct: 110 --GVVSTAQAYIADTSAPANRAKNFGLTGAAF 139


>UniRef50_Q2MDB3 Cluster: Tetracycline efllux protein; n=6;
           Proteobacteria|Rep: Tetracycline efllux protein -
           Acinetobacter baumannii
          Length = 363

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 8/86 (9%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           LG+ SD+ GR+ VLL  L G     + +T +         ++    + + +T A++A+ +
Sbjct: 30  LGALSDRWGRRPVLLISLAGSAINYLFLTFSHSL-----ILLLVGRIIAGITSANMAVAS 84

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTY 171
               YI DVS   NR    G+++ T+
Sbjct: 85  ---TYIVDVSQENNRAKYFGLINATF 107


>UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=2;
           Sphingomonadaceae|Rep: Major facilitator superfamily
           MFS_1 - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 412

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 30/119 (25%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 70  WNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYT 129
           W G+   V     +  LG+ SD+ GR+ +LL  L G      ++TV     W     ++ 
Sbjct: 49  WIGLVMAVATFLASPVLGNLSDRFGRRRILLLALGGLAVDYALLTVVETLPW-----LFV 103

Query: 130 AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
           A   S + G     +A   A IAD++  + R    G +   +      G AI    G +
Sbjct: 104 ARALSGIFGGS---YAAAQAAIADITPPEERARNFGFVGAAFGVGFVAGPAIGGFLGEM 159


>UniRef50_Q0RU88 Cluster: Putative membrane transport protein; n=1;
           Frankia alni ACN14a|Rep: Putative membrane transport
           protein - Frankia alni (strain ACN14a)
          Length = 502

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 136 LTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTV 195
           L GA   IF  CF  I D   V+ R++ +G++     +   +G  +  + G L   H T 
Sbjct: 109 LQGAGGGIFPLCFGIIRDEFPVEKRSVSIGLIS----AVTGLGGGLGLVLGGLFVDHATY 164

Query: 196 GKMMYVGATAAALGPIVAPLI 216
             + + GA  AAL  + + L+
Sbjct: 165 HWIFWSGAAMAALAAVGSQLL 185


>UniRef50_A6W364 Cluster: Major facilitator superfamily MFS_1
           precursor; n=2; Marinomonas|Rep: Major facilitator
           superfamily MFS_1 precursor - Marinomonas sp. MWYL1
          Length = 452

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFA 145
           +G +SDK GRK V++ GLL       +I  N  +       I T  +  A+ GA  AI +
Sbjct: 63  MGMWSDKIGRKRVIVIGLL-LFAVGSLICANASD-------INTLIVGRAIQGAG-AIAS 113

Query: 146 GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATA 205
              A ++DV+  +NRT  + I+ ++  ++  + +    + G  ++A   +  + Y+    
Sbjct: 114 TLMALLSDVTREQNRTKAMAIVGISIGASFMLSL----VLGPWIFALVGLSGLFYLSFAL 169

Query: 206 AALGPIV 212
           + LG ++
Sbjct: 170 SLLGIVL 176


>UniRef50_A4RGD5 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 544

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 3/42 (7%)

Query: 79  PLF--LAFFLGSYS-DKRGRKIVLLAGLLGKLYFSIMITVNT 117
           PLF  LA   G+Y  D+ GR+ ++LAGL G L+F +++T  T
Sbjct: 351 PLFGLLASIFGAYMLDRVGRRFMMLAGLSGALFFYVLLTAFT 392


>UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS family;
           n=17; Cyanobacteria|Rep: Multidrug efflux transporter,
           MFS family - Synechococcus sp. (strain WH8102)
          Length = 432

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 14/118 (11%)

Query: 82  LAFFLGSYSDKRGRKIVLL----AGLLGKLYFSIMITVNTMNDWPVEY-------VIYTA 130
           +A  +G+ SD+ GRK V+       ++G   F+I +TV     WP          +++TA
Sbjct: 74  VAPLIGALSDRFGRKPVISICVGGSVVGMGLFAITLTVPWQQIWPGAAAAGVPLALLFTA 133

Query: 131 ALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
            +   ++G   A      A +ADV++ +NR    G++ V +     +G  +  + G +
Sbjct: 134 RIIDGISGGTAATAT---AVLADVTTPENRAKAFGLIGVAFGLGFALGPGLGGVLGEM 188


>UniRef50_A2U0E9 Cluster: Sugar transporter; n=5; Flavobacteria|Rep:
           Sugar transporter - Polaribacter dokdonensis MED152
          Length = 444

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 5/122 (4%)

Query: 161 TLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSIT 220
           TLR G   +  LS L   IA+  I  ++   +  +  M+  G   AA+  I   ++    
Sbjct: 310 TLRFGGKKIYALSLLGTAIALFAIP-YISDPNLALVPMVLFGIGWAAMMGIPYTMV---- 364

Query: 221 SKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFL 280
           SK++P D RGV    L++M        ++ +  IY   +G   +N++ +  +   +  FL
Sbjct: 365 SKIVPQDRRGVYMGILNMMIVIPMFIQTLSFGPIYKYILGDNAVNAMLFAGVFFVISAFL 424

Query: 281 SA 282
           ++
Sbjct: 425 AS 426


>UniRef50_A1FU26 Cluster: General substrate transporter; n=1;
           Stenotrophomonas maltophilia R551-3|Rep: General
           substrate transporter - Stenotrophomonas maltophilia
           R551-3
          Length = 600

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 6/129 (4%)

Query: 113 ITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSS--VKNRTLRVGILDVT 170
           +  +T   WPV Y+++   L   L G D+ I AG   Y+   +S   +  + ++G +   
Sbjct: 9   VPASTAPRWPVRYLLFIGGLGGLLYGIDIGIIAGALPYLEATASHAWQLSSQQLGFVVAA 68

Query: 171 YLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERG 230
            L    +    A +   L+      G M+  G    A  PI+A L    T  LL    +G
Sbjct: 69  VLLGSVLSSLFAGMVADLIGRR---GAMLLAGLLFTASIPIMA-LASGYTPLLLGRLLQG 124

Query: 231 VAYAFLSVM 239
           ++   + V+
Sbjct: 125 ISGGLIGVV 133


>UniRef50_Q0DJA5 Cluster: Os05g0307100 protein; n=2; Oryza
           sativa|Rep: Os05g0307100 protein - Oryza sativa subsp.
           japonica (Rice)
          Length = 281

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 17/61 (27%), Positives = 35/61 (57%)

Query: 194 TVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQ 253
           ++ ++ Y+GA+   +  +V P IRSI SK   P E+G+    L+ + +   + + IV++ 
Sbjct: 176 SLSQVPYLGASFVIVSILVNPSIRSIVSKRAGPFEQGMVQGCLTGISSTANVISPIVFSP 235

Query: 254 I 254
           +
Sbjct: 236 L 236


>UniRef50_A2G4W0 Cluster: Nuclear division RFT1-like protein,
           putative; n=1; Trichomonas vaginalis G3|Rep: Nuclear
           division RFT1-like protein, putative - Trichomonas
           vaginalis G3
          Length = 445

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 14/88 (15%)

Query: 198 MMYVGATAAALGPIVAPLI-RSITSKLLPPDERGVAYA-FLSVM------------ENAV 243
           ++Y+G  AAA GP++AP++ +++ SK    D+   A + FL +M             NA 
Sbjct: 264 VVYIGLCAAAFGPLLAPVVLQTVYSKSWSGDDSKSAMSWFLRIMPFMAFNGVTEAFSNAR 323

Query: 244 AIFASIVYTQIYNATIGTEYINSIFYFT 271
               S++Y  I  A + + Y   IFYF+
Sbjct: 324 LSEKSLMYYNILLAIVSSIYFGLIFYFS 351


>UniRef50_A4YF51 Cluster: Major facilitator superfamily MFS_1
           precursor; n=1; Metallosphaera sedula DSM 5348|Rep:
           Major facilitator superfamily MFS_1 precursor -
           Metallosphaera sedula DSM 5348
          Length = 417

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 91  DKRGRKIVLLAGLLGKL-YFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFA 149
           D  GRK +LL  LLG L    I+ T+  +N    + + Y   L  AL G  ++ F+    
Sbjct: 64  DNLGRKTILLQLLLGLLGLLGIIFTLMHLNSLSSQLIYYLLLLFGALAGTGISTFSSGVT 123

Query: 150 YIADVSSVKNRTLRVGI 166
           Y++     K +   +GI
Sbjct: 124 YVSYFFPQKEQGKALGI 140


>UniRef50_Q88YJ0 Cluster: Multidrug transport protein; n=5;
           Lactobacillaceae|Rep: Multidrug transport protein -
           Lactobacillus plantarum
          Length = 398

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 49/235 (20%), Positives = 94/235 (40%), Gaps = 26/235 (11%)

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           I  E+ +T +     N + + +     +  +G  SDK GRK VL  GL+  +   ++  +
Sbjct: 33  IKNELHLTATDMGIMNALFA-LAQFVASPIIGRVSDKVGRKPVLTVGLVLYMVSEVLFAL 91

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
            T   W    V   + +   L+ A   +     A  +D+++ + R   +G L   +   L
Sbjct: 92  -TNQLW----VFNISRIVGGLSAA--MVVPTAMALASDITTKRQRAKVIGWLSAAFSGGL 144

Query: 176 PMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAF 235
            +G  I  +   + Y  T       +G  +A +  I+ P  R I      PD   +    
Sbjct: 145 ILGPGIGGVLAGISY-KTPFWVAGALGLLSAIVLVILLPADRQI-----DPDREAITATT 198

Query: 236 LSVMENAVAIFAS----IVYTQIYNATIGTE--------YINSIFYFTISTQVIV 278
            +        F +    I++T I  ++ G +        Y+N +F+F++S   +V
Sbjct: 199 TTTNHPMTRAFWTVPIIILFTMILVSSFGLQGFESIYSIYVNEVFHFSLSNIALV 253


>UniRef50_Q0C4X1 Cluster: Tetracycline-efflux transporter; n=1;
           Hyphomonas neptunium ATCC 15444|Rep: Tetracycline-efflux
           transporter - Hyphomonas neptunium (strain ATCC 15444)
          Length = 417

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 9/116 (7%)

Query: 74  ASHVVPLFL-AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAAL 132
           A++ V  FL    +G+ SDK GR+ VLL   +  L    ++     N W    +++   L
Sbjct: 60  ATYAVMTFLFGPLIGALSDKFGRRPVLLVS-MAMLGLDFLLMALAPNIW----ILF---L 111

Query: 133 PSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
             AL G   A ++   AYIAD ++ + R    G +  ++      G  I  + G L
Sbjct: 112 GRALAGISGATYSTANAYIADTTTPEERGRAFGFIGASFGLGFIFGPVIGGLLGEL 167


>UniRef50_A5FYH1 Cluster: Major facilitator superfamily MFS_1
           precursor; n=1; Acidiphilium cryptum JF-5|Rep: Major
           facilitator superfamily MFS_1 precursor - Acidiphilium
           cryptum (strain JF-5)
          Length = 413

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 10/102 (9%)

Query: 86  LGSYSDKRGRKIVLLAGLLGKLY-FSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           LG+ SD+ GR+ V+L   LG+   F++M    ++  W +   I        L+GA  A  
Sbjct: 71  LGALSDRFGRRPVILLSCLGQAVDFTVMALAPSVG-WLLAGRI--------LSGASSANI 121

Query: 145 AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           A   AYI+DV+  + R    G+  V       +G A+  + G
Sbjct: 122 AAANAYISDVTPPERRAAAFGVSGVAAAIGFVLGPALGGLLG 163



 Score = 35.1 bits (77), Expect = 2.0
 Identities = 18/89 (20%), Positives = 42/89 (47%), Gaps = 1/89 (1%)

Query: 174 TLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAY 233
           TL +G+ I    G +++      ++ ++G    +   +  P ++ I +  +   E+G   
Sbjct: 287 TLILGL-IGGAAGFVLFGLAPDSRIFWIGVPVLSAWGLAMPAVQGIMAHRIGGREQGRLQ 345

Query: 234 AFLSVMENAVAIFASIVYTQIYNATIGTE 262
             L+ +    A+   +++T IY AT+G +
Sbjct: 346 GLLASLNGLTALVGPLLFTTIYAATLGPD 374


>UniRef50_A0YM33 Cluster: General substrate transporter; n=4;
           Cyanobacteria|Rep: General substrate transporter -
           Lyngbya sp. PCC 8106
          Length = 421

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 15/110 (13%)

Query: 84  FFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMND-WPVEYVIYTAALPSALTGADLA 142
           F LG  +D +GRK+VLL G       + ++T+  +   W     I + A+  A  G  LA
Sbjct: 66  FGLGPLADSKGRKLVLLIG-------TTVVTLAPLGYLWVTS--IPSMAVIRAFHGVSLA 116

Query: 143 IFA-GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYA 191
            F  G  A +AD++ +  R   +G + +      P+G+AI    G  V A
Sbjct: 117 AFTIGYSALVADIAPIDRRGEVIGYMSL----VTPIGMAIGPAFGGFVQA 162


>UniRef50_A7SUG3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 259

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 16/75 (21%), Positives = 39/75 (52%)

Query: 181 IAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVME 240
           I+ I   +V+A  +   ++++      L   ++P+++ + ++L  PDERG A++ ++ + 
Sbjct: 167 ISLIASLVVFAFASKTWVVFLVPIVGLLTGTISPIMKGMITQLTRPDERGAAFSAVAAIS 226

Query: 241 NAVAIFASIVYTQIY 255
                  + V+  IY
Sbjct: 227 TFCNFLGAFVFNPIY 241


>UniRef50_Q4WVN5 Cluster: MFS multidrug transporter, putative; n=1;
           Aspergillus fumigatus|Rep: MFS multidrug transporter,
           putative - Aspergillus fumigatus (Sartorya fumigata)
          Length = 478

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 9/115 (7%)

Query: 165 GILDVTY-LSTLPMGIAIAHITGHL------VYAHTTVGKMMYVGATAAALGPIVAPLIR 217
           G+L  T  LS +     +A ++G L      + A   + +    G   +ALG       R
Sbjct: 328 GVLTATTSLSAMQKDRRMAQLSGILSAAGLGMVALAAIPEWYVAGLVISALGAGFIVFAR 387

Query: 218 SITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNA--TIGTEYINSIFYF 270
           S+ ++L+ P +R   YA ++V+++  A+ A  +   ++ A  T+G E +   F F
Sbjct: 388 SLATQLVTPAQRSTLYAAVAVVQSVGALAAGPLLADLFRAGLTLGREKMGLPFLF 442



 Score = 33.5 bits (73), Expect = 6.2
 Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 46  ICYNISKHADIN-KEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLL 104
           IC   +   D     VQ  ++  + W      +  + L+   G  +D+ GRK  LL GLL
Sbjct: 47  ICRQYTAQGDCKIAPVQSELAAVNGWKDTFDALPGILLSIPYGVLADRIGRKPCLLLGLL 106

Query: 105 GKLYFSIMITVNTM-NDWPVEY---VIYTAALPSALTGADLAIFAGCFAYIADVSSVKNR 160
           G +       +  M   WP      +++ A +   L G DL + +     +ADV   K+R
Sbjct: 107 GVILGESWTRLVCMFCFWPQILPLRLVWLAGVFRLLGGGDLVVSSLVSVIVADVFHDKDR 166

Query: 161 TLRVGILD----VTYLSTLPMGIAI 181
              +  L     +  L  +P+G A+
Sbjct: 167 ATALFQLSAAVMIAELLAIPLGGAL 191


>UniRef50_Q2HC27 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 468

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 4/115 (3%)

Query: 170 TYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDER 229
           T L+ + + + IA   G ++   +    +  VG T  ++G    PL R+IT+  + P + 
Sbjct: 325 TLLAKISLSLLIA---GAVIEGFSRGIALFLVGLTIGSIGSSHGPLCRAITTSYVEPQQT 381

Query: 230 GVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYI-NSIFYFTISTQVIVFLSAL 283
              YA +S++E   A+         +   +  + I   + +F ++  V+V L +L
Sbjct: 382 SRLYALISMLETGGAMLGGPALAWCFTIGLSKKGIWMGLPWFYVAGLVLVALVSL 436


>UniRef50_A7EHS0 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 731

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 7/72 (9%)

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           I K++  T S   Q   IA+ V   F+ FF G  +D+ GRKI LL GLL    FS+   +
Sbjct: 117 IGKDINATAS---QVTWIAAAVGGSFMLFF-GKVADELGRKIQLLIGLLFMSAFSL---I 169

Query: 116 NTMNDWPVEYVI 127
              +  P+E ++
Sbjct: 170 AAWSPGPIELIV 181


>UniRef50_UPI00015978DB Cluster: putative permease MDR type; n=1;
           Bacillus amyloliquefaciens FZB42|Rep: putative permease
           MDR type - Bacillus amyloliquefaciens FZB42
          Length = 555

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 171 YLSTLPM-GIAIA-HITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDE 228
           +LS L M G+ I  ++ G++ Y  +    ++ +  T  ALG ++ P + S   +L+PP++
Sbjct: 327 WLSGLGMLGLTITTYLYGYIRYDSSITPVIILLCLTGLALGLVIGPAMSS-GIRLIPPEK 385

Query: 229 RGVAYAFLSVMENAVAIFASIVYTQIYNATI 259
            G+A   L++M          + T +    I
Sbjct: 386 VGIASGILNMMRTVGQALGIAILTSVLTMNI 416


>UniRef50_Q2ARG1 Cluster: General substrate transporter:Major
           facilitator superfamily MFS_1; n=4; Bacillus|Rep:
           General substrate transporter:Major facilitator
           superfamily MFS_1 - Bacillus weihenstephanensis KBAB4
          Length = 399

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 45/200 (22%), Positives = 80/200 (40%), Gaps = 19/200 (9%)

Query: 87  GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG 146
           G+ SDK GRK V+  GLL     S  + +     W V        +   L G   A F+ 
Sbjct: 72  GAISDKYGRKKVIFIGLLALSIVSFFLGIVDSLFWLV--------ILRGLQGIAAATFSP 123

Query: 147 -CFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIA-----HITGHLVYAHTTVGKMMY 200
              AY+ ++  V+ +   +G +   +L     G  I+     H   H+V+   ++  +  
Sbjct: 124 VALAYVVEMFPVEKKVTTIGFVSTGFLVAGIAGQVISTAVSQHFGWHMVFFLLSI--VYI 181

Query: 201 VGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLS-VMENAVAIFASIVYTQIYNATI 259
           + A           + +S T  L P  + G  +   S V+   +A    + +  +Y  T+
Sbjct: 182 ITAVWIHYSLPKGEMSQSNTDILGPIKQMGKVFTHKSLVLSYMIAFVLLMAFVNMY--TV 239

Query: 260 GTEYINSIFYFTISTQVIVF 279
              Y++S  Y  I  Q++ F
Sbjct: 240 LGNYLSSPTYNLIPEQILYF 259


>UniRef50_Q1QFP1 Cluster: Major facilitator superfamily MFS_1; n=1;
           Nitrobacter hamburgensis X14|Rep: Major facilitator
           superfamily MFS_1 - Nitrobacter hamburgensis (strain X14
           / DSM 10229)
          Length = 413

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 21/165 (12%)

Query: 76  HVVPLFL-AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPS 134
           + + LFL A   G  SD+ GR+I+LL GL+G  + + M+T   + +      +Y     S
Sbjct: 50  YTLALFLFAPAWGHMSDRYGRRIILLIGLIG--FSATMLTFAFIENLT---AVYAERFLS 104

Query: 135 ALTGADLAIFAGCFAYIADVSSV-KNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHT 193
            +  A  A+  G  A I D+++  + R  R+  + +  +S    G  +  + G  V+   
Sbjct: 105 GMFAA--AVTPGALATIGDLAATDEARARRLTFVSLAGIS----GFLLGPMLG--VFVVR 156

Query: 194 TVGKMMYVGATAAAL------GPIVAPLIRSITSKLLPPDERGVA 232
           + G ++ +G  A AL        ++A L+ +  +  +P  +RG A
Sbjct: 157 SAGSLLPIGGGAGALTLPLAGTAVLALLVAAAAAVTVPGVKRGDA 201


>UniRef50_A6GIA5 Cluster: Transporter, major facilitator family
           protein; n=1; Plesiocystis pacifica SIR-1|Rep:
           Transporter, major facilitator family protein -
           Plesiocystis pacifica SIR-1
          Length = 417

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 14/134 (10%)

Query: 83  AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLA 142
           A F G  SD  GR+ +L A   G L+  + + ++   D    + +  A     LTGA   
Sbjct: 74  AVFAGPISDHYGRRTILRA---GSLFMGVALVLHAFAD---SFAVLLAL--RMLTGASSG 125

Query: 143 IFAG-CFAYIADVSSVKNRTLRVG-ILD---VTYLSTLPMGIAIAHITG-HLVYAHTTVG 196
           I +G   AYI D+   + R   +G IL       ++ +P+G  +A   G    +    V 
Sbjct: 126 ILSGAAVAYIGDILPYERRGAALGWILSGMAFGQIAGVPLGTVLAGEVGFQSPFVVFGVV 185

Query: 197 KMMYVGATAAALGP 210
            ++  G T  AL P
Sbjct: 186 MLLAFGGTVVALVP 199


>UniRef50_A6F246 Cluster: Mg/Co/Ni transporter MgtE; n=1;
           Marinobacter algicola DG893|Rep: Mg/Co/Ni transporter
           MgtE - Marinobacter algicola DG893
          Length = 397

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 31/123 (25%), Positives = 49/123 (39%), Gaps = 15/123 (12%)

Query: 48  YNISKHADINKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVL------LA 101
           Y ++K   IN  V       H W  + + +     AF +G +     + + L      LA
Sbjct: 208 YGVAKEEQINTPVLAAFRMRHPWLQV-NLITAFAAAFVVGMFESTIAQIVALAAFLPVLA 266

Query: 102 GLLGKLYFSIM------ITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG--CFAYIAD 153
           G  G      +      IT+  +ND+P+  ++    L  AL GA + + AG   FAY   
Sbjct: 267 GQSGNTGCQALAITLRGITLGQINDYPIRRLLRKEVLLGALNGAAVGVIAGIAMFAYALS 326

Query: 154 VSS 156
             S
Sbjct: 327 TDS 329


>UniRef50_Q7S282 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 669

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 186 GHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAI 245
           G LV+A +   + ++V  T   LG    P  RS+ + L+ PD  G+ +  L++M+ A ++
Sbjct: 503 GVLVWAPSL--RYVFVSLTLYTLGSGFYPFGRSLLASLVEPDMIGILFTTLAMMDTAGSL 560

Query: 246 FASIVYTQIYNATIGTE 262
            A       +  ++G E
Sbjct: 561 MAGPAVAWTFGWSLGLE 577


>UniRef50_Q6CLW6 Cluster: Similarities with sp|P46996 Saccharomyces
           cerevisiae YJL163c singleton; n=1; Kluyveromyces
           lactis|Rep: Similarities with sp|P46996 Saccharomyces
           cerevisiae YJL163c singleton - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 591

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 22/97 (22%), Positives = 49/97 (50%), Gaps = 5/97 (5%)

Query: 188 LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFA 247
           LV  +++ G  +Y+     +L  +++P+ +S  +K     + G  +  ++++ +   +  
Sbjct: 469 LVCVNSSTG--VYISGVLQSLSGMISPVTQSAIAKYSSKTDAGEMFGAIALIRHLGMLLF 526

Query: 248 SIVYTQIYNATIGTEYINSIF-YFTISTQVIVFLSAL 283
            I++ QIY+ TI  E+    F Y  +   V  FLS++
Sbjct: 527 PILFLQIYSHTI--EFSAKFFLYLPLFVSVATFLSSV 561


>UniRef50_A7D0E0 Cluster: Major facilitator superfamily MFS_1; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Major
           facilitator superfamily MFS_1 - Halorubrum lacusprofundi
           ATCC 49239
          Length = 453

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 4/144 (2%)

Query: 74  ASHVVPLFLAF-FLGSYSDKRGRKIVLLAGL--LGKLYFSIMITVNTMNDWPVEYVIYTA 130
           AS+ +  FLA   LG  SD+ GR+ VLLA L   G  + +      +   +     + T 
Sbjct: 69  ASYSLAQFLAAPTLGRLSDRIGRRPVLLASLATAGVAWVTFGYAGESGARFGTAAALATL 128

Query: 131 ALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAH-ITGHLV 189
                L GA     A   AY+AD++    R   +G++  ++      G AI   +    V
Sbjct: 129 FASRTLAGAMGGNIAAAQAYVADITPRDRRAGALGLVGASFALGFVFGPAIGGLLAADAV 188

Query: 190 YAHTTVGKMMYVGATAAALGPIVA 213
            A        +V ATA +L    A
Sbjct: 189 VARADALLPAFVPATAYSLPSFAA 212


>UniRef50_P46996 Cluster: Uncharacterized membrane protein YJL163C;
           n=2; Saccharomyces cerevisiae|Rep: Uncharacterized
           membrane protein YJL163C - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 555

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 26/121 (21%), Positives = 59/121 (48%), Gaps = 3/121 (2%)

Query: 60  VQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVL--LAGLLGKLYFSIMITVNT 117
           VQ  VS+      + +  + +F+A   G  SD+ GR  V   ++G+      + + T+++
Sbjct: 123 VQTIVSSISSSTMMIAGAISIFMAGKWGELSDRIGRVRVFKYMSGIRVIGLLTHVFTLSS 182

Query: 118 MNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPM 177
              +    ++ TA +  +  G   A+ A   +Y++D+   ++R + +GI+     +T+ +
Sbjct: 183 KMKYHKWAIVLTACIVPSFGGL-FALVANGNSYVSDIVKTEHRMVTIGIMMSCIYATMGV 241

Query: 178 G 178
           G
Sbjct: 242 G 242


>UniRef50_Q28RT4 Cluster: Major facilitator superfamily MFS_1; n=16;
           Bacteria|Rep: Major facilitator superfamily MFS_1 -
           Jannaschia sp. (strain CCS1)
          Length = 406

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 17/68 (25%), Positives = 34/68 (50%)

Query: 188 LVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFA 247
           + Y   T   M++     +A+G +VAP ++ + S+    D++G     L+ + +   I +
Sbjct: 293 ICYGLATEAWMIWALIPVSAMGAVVAPAMQGVMSRAAGADQQGELQGVLASISSLSMILS 352

Query: 248 SIVYTQIY 255
            IV TQ +
Sbjct: 353 PIVMTQAF 360


>UniRef50_Q1DG35 Cluster: Drug resistance transporter, EmrB/QacA
           family; n=1; Myxococcus xanthus DK 1622|Rep: Drug
           resistance transporter, EmrB/QacA family - Myxococcus
           xanthus (strain DK 1622)
          Length = 583

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 40/145 (27%), Positives = 62/145 (42%), Gaps = 9/145 (6%)

Query: 65  STFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVE 124
           ++ + W   +  V    +    G  SD  GR+ VL AG+L  L  S +  V       V 
Sbjct: 60  ASLYPWLTTSYFVASTTMVPVWGKLSDLLGRRAVLAAGILIFLAGSFLCGVARST---VA 116

Query: 125 YVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTY-LSTLPMGIAIAH 183
            +++ A     L  A  A+F    A +AD+   + R    G+    + LS++   +A   
Sbjct: 117 LILFRAV--QGLGSA--ALFTAALAVVADLFEPRERGKYQGLFGAMFGLSSVVGPLAGGF 172

Query: 184 ITGHLVYAHTTVGKMMYVGATAAAL 208
           IT HL + H      + VGA A AL
Sbjct: 173 ITDHLGW-HWVFFINLPVGAVALAL 196


>UniRef50_A2SG94 Cluster: Tetracycline-efflux transporter; n=2;
           Proteobacteria|Rep: Tetracycline-efflux transporter -
           Methylibium petroleiphilum (strain PM1)
          Length = 418

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 70  WNGIASH---VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYV 126
           W G+ +    +   F +  LG+ SD+ GR+ VLL G  G L  +   T  +   W +  V
Sbjct: 50  WFGVVTFAFAIANFFGSPILGALSDRYGRRPVLLIGFCG-LALNFFFTALSTALWMLVAV 108

Query: 127 IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
                    + GA  A  A   AY+AD++  + R  R G+L   +     +G  +  + G
Sbjct: 109 -------RLVGGAMQANAAVANAYVADITPPEQRARRFGLLGAMFGLGFILGPVLGGLLG 161


>UniRef50_A1R2T1 Cluster: Putative major facilitator superfamily
           (MFS) transporter; n=2; Micrococcineae|Rep: Putative
           major facilitator superfamily (MFS) transporter -
           Arthrobacter aurescens (strain TC1)
          Length = 455

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 16/34 (47%), Positives = 22/34 (64%)

Query: 70  WNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGL 103
           W  +AS ++ LFL  F G  SDK GRK ++ AG+
Sbjct: 288 WVVLASCILGLFLIPFFGKLSDKFGRKPIIFAGV 321


>UniRef50_Q6BTW2 Cluster: Similar to tr|Q9HF77 Candida albicans
           Fluconazole resistance protein; n=1; Debaryomyces
           hansenii|Rep: Similar to tr|Q9HF77 Candida albicans
           Fluconazole resistance protein - Debaryomyces hansenii
           (Yeast) (Torulaspora hansenii)
          Length = 529

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 11/110 (10%)

Query: 87  GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG 146
           G  SD  GRKI+L++   G +Y ++   V T  +  ++ +I         + A + +   
Sbjct: 142 GPLSDVYGRKIILISS--GFIYLTLNFAVATAEN--IQTIIICRFFSGFASAAPVVV--- 194

Query: 147 CFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVG 196
           C A IA+VS+  NR    G +   ++  L +G  +A I    +  + ++G
Sbjct: 195 CAAIIAEVSNTSNR----GNIITMFVMVLLVGPLLAPIVNGFIVKNNSLG 240


>UniRef50_Q3ZXW4 Cluster: Major facilitator family transporter; n=2;
           Dehalococcoides|Rep: Major facilitator family
           transporter - Dehalococcoides sp. (strain CBDB1)
          Length = 423

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 180 AIAHITGHLVYAHTTVGKMMYVGATAAALGPIV-APLIRSITSKLLPPDERGVAYAFLSV 238
           ++ +  G+L++A TT   M ++  +   +G IV AP   ++   L PP +RG    F   
Sbjct: 301 SLIYAVGYLMFAWTTNLGMAFLAMSVITMGEIVFAPTTLAVVGDLSPPQQRGRYMGFYGF 360

Query: 239 ME 240
            E
Sbjct: 361 SE 362


>UniRef50_Q1IVW2 Cluster: Major facilitator superfamily MFS_1; n=1;
           Deinococcus geothermalis DSM 11300|Rep: Major
           facilitator superfamily MFS_1 - Deinococcus geothermalis
           (strain DSM 11300)
          Length = 411

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 70  WNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYT 129
           W G +  ++  F A  LG+ SD  GR+ VL+  LLG     ++  +           +  
Sbjct: 56  WLGASYALLSFFAAPVLGALSDAYGRRPVLMLSLLGSAVGYVIFGIGGS--------LVM 107

Query: 130 AALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
             L  ++ G      +  F Y+AD +  ++R    G +  T  +   +G A+     HL
Sbjct: 108 LFLGRSIDGLTAGGMSALFGYLADTTPEEDRGRVFGQVGATVGAGFIIGPAVGGALSHL 166


>UniRef50_A7FUI5 Cluster: Major facilitator family protein; n=4;
           Clostridium botulinum|Rep: Major facilitator family
           protein - Clostridium botulinum (strain ATCC 19397 /
           Type A)
          Length = 394

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 16/130 (12%)

Query: 72  GIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIY 128
           G+A  +  L  AFF    G +SDK G K V+L GL+ ++   +++     N       IY
Sbjct: 51  GVALGIFGLMQAFFQIPFGVFSDKFGNKKVILIGLM-QVIIGLLLAYFAKN-------IY 102

Query: 129 TAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHL 188
              +  AL G+  AI A  +++I+     + RT  + I+ +     L      +   G +
Sbjct: 103 LLIVARALQGSG-AIIAVGYSWISSSVHCEKRTRAISIVGI----ILGFAATASFALGPI 157

Query: 189 VYAHTTVGKM 198
           ++ + +V  M
Sbjct: 158 IHKYVSVNNM 167


>UniRef50_A6G4P7 Cluster: Antibiotic resistance protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Antibiotic resistance
           protein - Plesiocystis pacifica SIR-1
          Length = 401

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 9/109 (8%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAG-----LLGKLYFSIMITVNTMNDWPVEYVIYTAA 131
           V  +F    +G   D RGR+IV L G     L   LY ++     T+++ P   +    A
Sbjct: 58  VAAIFARPVVGKVMDTRGRRIVTLVGGLIHVLSSGLYLALDAHAGTLSE-PSPSLWLLVA 116

Query: 132 LPSALTGADLA-IFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGI 179
               + G  LA +F+  F   AD+   + R   + I  V+ L  +P+GI
Sbjct: 117 CVRVVHGLGLAALFSVLFTIAADIVPAQRRAEGIAIYGVSGL--IPLGI 163


>UniRef50_A3I0S1 Cluster: Multidrug transporter, putative; n=1;
           Algoriphagus sp. PR1|Rep: Multidrug transporter,
           putative - Algoriphagus sp. PR1
          Length = 408

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKL--YFSIMITVNTMNDWPVEYVIYTAALPS 134
           ++  F A  LG+ SD+ GRK +L+  ++G L  Y      +   N W    +++ + L  
Sbjct: 67  LMQFFGAPILGALSDRFGRKKMLILSIIGVLIGYLLFAWAIIIKNLW----LLFFSRLLP 122

Query: 135 ALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
              G +++I     + I+D+S  K +T   G+  + +     +G A+    G
Sbjct: 123 GFAGGNVSI---AMSAISDISEEKEKTKNFGLAGMAFGIGFILGPALGGFLG 171


>UniRef50_A0UKQ2 Cluster: Major facilitator superfamily MFS_1; n=2;
           Burkholderia cepacia complex|Rep: Major facilitator
           superfamily MFS_1 - Burkholderia multivorans ATCC 17616
          Length = 439

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 12/135 (8%)

Query: 90  SDKRGRKIVLLAGLLGKLYFSI-MITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCF 148
           SD+ GR+ VL+AGL+G       + T++  +D    Y     AL + LT   + I     
Sbjct: 293 SDRIGRRPVLIAGLIGAAVAGCSLFTLSPGSD----YAHLQLALIACLTCHGI-ILGPMA 347

Query: 149 AYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAAL 208
           AY+A++   +   +R   L  +Y     +G +IA I G L+ ++T  G  ++V   A  +
Sbjct: 348 AYMAELFPTR---VRFTALSTSYQLASVLGGSIAPIVGTLLVSYT--GSAIFVAGYAILM 402

Query: 209 G-PIVAPLIRSITSK 222
             P    +I S  S+
Sbjct: 403 ALPAFVAVIASRESR 417


>UniRef50_Q86EF4 Cluster: Clone ZZD455 mRNA sequence; n=3;
           Schistosoma japonicum|Rep: Clone ZZD455 mRNA sequence -
           Schistosoma japonicum (Blood fluke)
          Length = 420

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 7/89 (7%)

Query: 25  VIEQTFYVFQTCHINHGYS-------TEICYNISKHADINKEVQVTVSTFHQWNGIASHV 77
           VIE+  YV+   H++ GY          I Y  +   D +      + TF+ +N + + +
Sbjct: 217 VIERILYVYYKTHVSQGYVQGMNEIIAPIYYVFATDPDESWRKYAEMDTFYCFNNLMTEI 276

Query: 78  VPLFLAFFLGSYSDKRGRKIVLLAGLLGK 106
            P F+    GS+    G ++ +L+ LL K
Sbjct: 277 HPNFIRKLDGSHEAGLGGQMKILSNLLLK 305


>UniRef50_A1RTX0 Cluster: Major facilitator superfamily MFS_1; n=5;
           Thermoproteales|Rep: Major facilitator superfamily MFS_1
           - Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
          Length = 413

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 13/132 (9%)

Query: 83  AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT-MNDWPVEYVIYTAALPSALTGADL 141
           A F G  +D+ GR      GL+G L   +++ +   +   P+E +  TA L   LT    
Sbjct: 267 AIFFGRLADRWGRVKTFRLGLVGGLAALLVLNIALHLGLGPLESIALTAPL-LFLTS--- 322

Query: 142 AIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYV 201
           AI     A I D + ++ R   +GI    Y   L +GI I  + G  +   +++ +   +
Sbjct: 323 AIGPSILALIGDEADIRYRGTTMGI----YSVVLGLGIGIGSLLGGAI---SSISRQYAI 375

Query: 202 -GATAAALGPIV 212
            G   AALG  V
Sbjct: 376 NGLATAALGVYV 387


>UniRef50_Q83C69 Cluster: Uncharacterized protein CBU_1260
           precursor; n=3; Coxiella burnetii|Rep: Uncharacterized
           protein CBU_1260 precursor - Coxiella burnetii
          Length = 248

 Score = 33.9 bits (74), Expect = 4.7
 Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 140 DLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMM 199
           D+ I        + V +   + + +  +D+   +TLP+    A I G + Y HT   K +
Sbjct: 109 DVNIAGSALPLFSSVQAEGRQKINLYSIDLMGKATLPIDNFYAFIEGGVAYVHT---KFV 165

Query: 200 YVGATAAALGPIVAPLIRSITSKLLPPDERG 230
               T  A+ P++ P+  S+  K +P   +G
Sbjct: 166 AFTETGTAVSPLLPPVTSSVAVK-VPSSSKG 195


>UniRef50_UPI0000E4618C Cluster: PREDICTED: hypothetical protein,
            partial; n=1; Strongylocentrotus purpuratus|Rep:
            PREDICTED: hypothetical protein, partial -
            Strongylocentrotus purpuratus
          Length = 1392

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 6/117 (5%)

Query: 146  GCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVG-KMMYVG-A 203
            G   +++   + +NR L  G+  VT        +A   I G  +Y  T VG K + +G  
Sbjct: 1003 GQILFLSLAEATENRALCKGVT-VTLHYLFTSALAWTMIEGVFLYRTTAVGCKTLRIGWL 1061

Query: 204  TAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVY-TQIYNATI 259
            +  A G  +  ++  ++  +L       AY +L V +N++ IFA  VY T++++ T+
Sbjct: 1062 SLIAYGGSL--VVVGVSFGVLFDTYGTSAYCWLHVEDNSIYIFAGCVYATELFSFTV 1116


>UniRef50_UPI0000DAE55E Cluster: hypothetical protein
           Rgryl_01000616; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000616 - Rickettsiella
           grylli
          Length = 394

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 8/114 (7%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFL---AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           ++Q ++   H +  +A  +  +F+   A  LG+ SD  GRK+VLL GLLG     +   +
Sbjct: 17  KIQTSLLLRHFYYNLAISLPTIFVCMGALILGALSDLIGRKMVLLIGLLGVAIACLFSAI 76

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDV 169
                  + ++I    L   + G + A+   C   +AD+S+ K + + +  + +
Sbjct: 77  GVKTHNIILFLI-GRVLMGIMDGNE-AVAQAC---MADLSNNKEKAINMSYVSL 125


>UniRef50_UPI0000499E89 Cluster: major facilitator superfamily
           protein; n=2; Entamoeba histolytica HM-1:IMSS|Rep: major
           facilitator superfamily protein - Entamoeba histolytica
           HM-1:IMSS
          Length = 528

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 8/88 (9%)

Query: 83  AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLA 142
           +FFLG  SD  GR+ +LL G LG L  S ++   + N W   + + + ++ + L   ++ 
Sbjct: 81  SFFLGVLSDNIGRRPILLIGSLGSL-ISTLLFGFSFNYW---WAVISRSI-NGLVNGNIG 135

Query: 143 IFAGCFAYIADVSSVKNRTLRVGILDVT 170
           +      ++ + S+ +NR    G++ +T
Sbjct: 136 VIK---TFMGEFSTKENRAQVFGLIGLT 160


>UniRef50_Q97L04 Cluster: Permease, probably tetracycline resistance
           protein; n=30; Firmicutes|Rep: Permease, probably
           tetracycline resistance protein - Clostridium
           acetobutylicum
          Length = 411

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 81  FLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGAD 140
           F A  LG+ SDK GR+ VLL  LLG     ++  +         +V++   +   +TG  
Sbjct: 73  FSAPGLGALSDKYGRRPVLLVCLLGSSIGYLIFGIG-----GALWVLFAGRIIDGITGGT 127

Query: 141 LAIFAGCFAYIADVSSVKNRTLRVG 165
           ++     FAY AD+     RT   G
Sbjct: 128 ISTI---FAYFADIIPENERTKYFG 149


>UniRef50_Q8DIK2 Cluster: Tlr1583 protein; n=8; Cyanobacteria|Rep:
           Tlr1583 protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 468

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 165 GILDVTYLSTLPMGIAIAH--ITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSK 222
           GIL V   + LP+G+ ++   +   LV+A  T+G + +  A    +  +++PL+ +I   
Sbjct: 189 GILRVFAATALPLGLILSEPDLGTSLVFAAITLGMLYWANARLGWIVLMLSPLVAAILFA 248

Query: 223 LLPPDERGVAYAFLSVMENAVAIFASI 249
           L  P E  +   FL  +   V  + S+
Sbjct: 249 LPLPYELNLVLWFLWTLGMGVVAWQSL 275


>UniRef50_Q62FE5 Cluster: Major facilitator family transporter;
           n=39; Betaproteobacteria|Rep: Major facilitator family
           transporter - Burkholderia mallei (Pseudomonas mallei)
          Length = 385

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 15/138 (10%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSAL 136
           V    L  F G  SDK GRK V+ AGLL    F++   V       + ++I    +   +
Sbjct: 55  VTQSLLYIFYGWASDKFGRKPVIAAGLL---IFALGSFVAAFAH-DITWII----VGRVI 106

Query: 137 TGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTV- 195
            G   A+ +   A+IAD++S  NRT  + ++      ++ M  A+A +   +V+    + 
Sbjct: 107 QGMG-AVSSAVLAFIADLTSEHNRTKAMAMVG----GSIGMSFAVAIVGAPIVFHWVGMS 161

Query: 196 GKMMYVGA-TAAALGPIV 212
           G    VGA + AA+G ++
Sbjct: 162 GLFAIVGALSVAAIGVVL 179


>UniRef50_Q0SDT0 Cluster: Metabolite transporter, MFS superfamily
           protein; n=5; Actinomycetales|Rep: Metabolite
           transporter, MFS superfamily protein - Rhodococcus sp.
           (strain RHA1)
          Length = 438

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 70  WNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYT 129
           W G+ +++V +    F G+ SD+ GRK VL  G +G    +++  +N M       + + 
Sbjct: 288 WAGVGANLVLIASLPFWGALSDRIGRKPVLYIGNVG--IAALLFPLNAMIGHSAVTLFFA 345

Query: 130 AALPSALTGADLAIFAGCFA 149
            A+   + GA L++     A
Sbjct: 346 MAIALFVMGAILSVMPAMMA 365


>UniRef50_A6E8D0 Cluster: Kynureninase; n=1; Pedobacter sp.
           BAL39|Rep: Kynureninase - Pedobacter sp. BAL39
          Length = 449

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 18/77 (23%), Positives = 35/77 (45%)

Query: 58  KEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNT 117
           K   +T   F+  N + + +  +       S ++ RG ++ ++A   GK  F  ++  N 
Sbjct: 353 KSKALTAYLFYLINEVNNELCEMQYQVITPSSAEDRGAQVSIIAKANGKYIFEQLVANNV 412

Query: 118 MNDWPVEYVIYTAALPS 134
           + DW    VI  + +PS
Sbjct: 413 LGDWREPNVIRLSPVPS 429


>UniRef50_A4X8R4 Cluster: Drug resistance transporter, EmrB/QacA
           subfamily; n=1; Salinispora tropica CNB-440|Rep: Drug
           resistance transporter, EmrB/QacA subfamily -
           Salinispora tropica CNB-440
          Length = 564

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 24/106 (22%), Positives = 46/106 (43%)

Query: 177 MGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFL 236
           +G+A   +T  L     T  +++ +     A+G I+ P + ++   L  P ERG A+A +
Sbjct: 108 IGVAGFTLTSLLAGLAQTPEQLIVLRFVQGAMGAIMVPQVYTLIQLLYAPKERGRAFAAM 167

Query: 237 SVMENAVAIFASIVYTQIYNATIGTEYINSIFYFTISTQVIVFLSA 282
           S       +   +V   +  A I      +IF   +   +  F++A
Sbjct: 168 SAALAFGTVGGPLVGALLTTADIAGLGWRAIFLVNVPIGIAAFIAA 213


>UniRef50_A3WGM5 Cluster: Transporter, NRAMP family protein; n=1;
           Erythrobacter sp. NAP1|Rep: Transporter, NRAMP family
           protein - Erythrobacter sp. NAP1
          Length = 407

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 5/83 (6%)

Query: 169 VTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAAL--GPIVAPLIRSITSKLLPP 226
           + Y   +P+ IA+   T  ++YA T+    M   AT+AA    P++A L   + ++   P
Sbjct: 321 IVYRIAIPVLIAL---TAAVLYAFTSSFTAMLDLATSAAFVGAPVIATLNHLVVTRCSMP 377

Query: 227 DERGVAYAFLSVMENAVAIFASI 249
           +E   + AF ++   A+A+ AS+
Sbjct: 378 EEARPSKAFRALNLFAIAVMASL 400


>UniRef50_A3UHT7 Cluster: Major facilitator family transporter; n=1;
           Oceanicaulis alexandrii HTCC2633|Rep: Major facilitator
           family transporter - Oceanicaulis alexandrii HTCC2633
          Length = 414

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 10/119 (8%)

Query: 103 LLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTL 162
           L+  +Y   M+T      WP    I +  +   L  A L+I +GCFA I  V    +  L
Sbjct: 239 LMAVIYLGSMVT-----QWPAG--IISDKMDRRLVIAALSIMSGCFALILVVMPNPDLLL 291

Query: 163 R---VGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPIVAPLIRS 218
               VG+     L+   + +A A     +         M+ V A  + LGPIVA +  S
Sbjct: 292 AAILVGLWGAASLAYYSVAVAHAADRSRVEELPAIASGMLLVWAAGSTLGPIVAGIAYS 350


>UniRef50_A0YH94 Cluster: Putative transmembrane efflux protein;
           n=1; marine gamma proteobacterium HTCC2143|Rep: Putative
           transmembrane efflux protein - marine gamma
           proteobacterium HTCC2143
          Length = 465

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 56  INKEVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           I +E++V+      W+  A  ++      FLG   D  G + + L G++G   F+++   
Sbjct: 46  IAQELKVS-EALASWSVSAPMLISAVCMPFLGKLGDLYGHRRIFLIGIVGSTMFALLCYF 104

Query: 116 NTMNDWPVEYVIYTAALPSALTGADLAIFAGCF 148
            T   W V   I + A   A T + +A+    F
Sbjct: 105 ATNIWWLVGLRILSMAFAGATTPSAMALIFHVF 137


>UniRef50_A0ISG2 Cluster: Major facilitator superfamily MFS_1; n=5;
           Proteobacteria|Rep: Major facilitator superfamily MFS_1
           - Serratia proteamaculans 568
          Length = 459

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 9/86 (10%)

Query: 83  AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADL- 141
           A   G YSD+ GRK VLL  +L    FS++   +T    P+E      AL   LTG  L 
Sbjct: 76  ALIAGPYSDRFGRKKVLLLSILCFALFSLL---STFARTPLE-----MALLRFLTGLGLG 127

Query: 142 AIFAGCFAYIADVSSVKNRTLRVGIL 167
           A+   C   +++    + R L + ++
Sbjct: 128 AVMPNCVTLVSEYMPERRRGLMITLM 153


>UniRef50_O28265 Cluster: Sugar transporter, putative; n=1;
           Archaeoglobus fulgidus|Rep: Sugar transporter, putative
           - Archaeoglobus fulgidus
          Length = 401

 Score = 33.5 bits (73), Expect = 6.2
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 13/117 (11%)

Query: 74  ASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALP 133
           A ++  +F A   G   D+ GRK  L+  +L    FS+ ++    N W       T A+ 
Sbjct: 54  AQYIFCIFGAMLFGEMGDRFGRKNALILSILWVAVFSV-LSAFAPNFW-------TLAIL 105

Query: 134 SALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVY 190
             ++G  +  +   F Y+++  S K R L  G++  T++     G  ++ ++  L+Y
Sbjct: 106 RLISGMGVT-WGLAFTYMSEFYSPKRRGLFGGLIHATFV----FGFILSALSVSLIY 157


>UniRef50_Q9RN46 Cluster: 12-TMS multidrug efflux protein homolog;
           n=4; Proteobacteria|Rep: 12-TMS multidrug efflux protein
           homolog - Salmonella typhi
          Length = 413

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 9/96 (9%)

Query: 73  IASHVVPLFLAF-FLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAA 131
           IA+     F A   +G  SD+ GRK +L+   L     S+++  N          I    
Sbjct: 61  IATEAFSQFCAAPLIGHLSDRVGRKRILIV-TLAIAAISLLLLANAQ-------CILFIL 112

Query: 132 LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGIL 167
           L   L G      +   AYIAD + V+NR   +GIL
Sbjct: 113 LARTLFGISAGNLSAAAAYIADCTHVRNRRQAIGIL 148


>UniRef50_Q75TC8 Cluster: Multidrug-efflux transporter; n=3;
           Geobacillus|Rep: Multidrug-efflux transporter -
           Geobacillus kaustophilus
          Length = 394

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 7/81 (8%)

Query: 87  GSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAG 146
           G+ SD+ GRK +LL G+ G      ++ V T       ++++ A +      A  A    
Sbjct: 66  GNLSDRYGRKPMLLVGIFGLALSFFLLAVATK-----LWMLFAARIIGGCLSA--ATMPA 118

Query: 147 CFAYIADVSSVKNRTLRVGIL 167
             AY+ADV++ ++R   +G++
Sbjct: 119 AMAYVADVTTEEDRGKGMGMI 139


>UniRef50_Q53903 Cluster: ActVA 1 protein; n=1; Streptomyces
           coelicolor|Rep: ActVA 1 protein - Streptomyces
           coelicolor
          Length = 533

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 38/149 (25%), Positives = 67/149 (44%), Gaps = 19/149 (12%)

Query: 84  FFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAALPSALTGADLAI 143
           F  G   D+ GR+ VLL G LG   F +          P + +   A +   ++GA  A+
Sbjct: 77  FTWGVLGDRLGRRRVLLLG-LG--LFGLSSLAGAYAGSPEQLIAARACM--GVSGA--AV 129

Query: 144 FAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGA 203
                A IA V  ++ R   +GI    + +++   + I  +TG ++ AH   G ++ V  
Sbjct: 130 LPSTLATIAAVFPLRERPKALGI----WAASVGFALGIGPVTGGILLAHFWWGSVLLVNV 185

Query: 204 TAAALGPIVAPLIRSITSKLLPPDERGVA 232
                 P++A  + ++   L+ P+ RG A
Sbjct: 186 ------PLMAGCLVAVV--LVVPETRGTA 206


>UniRef50_Q3B5W4 Cluster: VCBS; n=2; cellular organisms|Rep: VCBS -
           Pelodictyon luteolum (strain DSM 273) (Chlorobium
           luteolum (strain DSM273))
          Length = 7284

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 8/104 (7%)

Query: 110 SIMITVNTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILD- 168
           S MITV  +ND PV  V       SA+T A+    A     +AD     + T+ + + + 
Sbjct: 349 STMITVTAVNDAPVNTV------SSAVTVAEDTAIAITGLSVADADDTSDITVTLSVTNG 402

Query: 169 -VTYLSTLPMGIAIAHITGHLVYAHTTVGKMMYVGATAAALGPI 211
            +T   ++  G+    I G+     T  G +  + AT A  G +
Sbjct: 403 TITVAESVTSGLVTTDIGGNGTGTVTLTGTVAEINATLADTGAV 446


>UniRef50_Q0SUN9 Cluster: Putative uncharacterized protein; n=1;
           Clostridium perfringens SM101|Rep: Putative
           uncharacterized protein - Clostridium perfringens
           (strain SM101 / Type A)
          Length = 128

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 22/95 (23%), Positives = 46/95 (48%), Gaps = 7/95 (7%)

Query: 92  KRGRKIVLLAGLLGKLYFSIMI-------TVNTMNDWPVEYVIYTAALPSALTGADLAIF 144
           K+  KI+L++G++G +Y  ++I       +V  ++D  +E  +   A+   +    L + 
Sbjct: 4   KKRSKILLVSGIIGTIYSLLLIRFFLAYFSVGIISDIDIEKAVSALAVIIVIPHMVLFVL 63

Query: 145 AGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGI 179
           A  F + + + + +   L  GIL +  L   PM +
Sbjct: 64  ATIFNWFSYIKNKRGFALSAGILYLISLIVFPMDL 98


>UniRef50_Q0LMR4 Cluster: Major facilitator superfamily MFS_1
           precursor; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: Major facilitator superfamily MFS_1 precursor
           - Herpetosiphon aurantiacus ATCC 23779
          Length = 391

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 13/145 (8%)

Query: 73  IASHVVPLFL-AFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYVIYTAA 131
           + S+ +  F+ A  LG  SD+ GR+ +L+  L+G +   ++        W     ++   
Sbjct: 45  VGSYALMQFIFAPILGQLSDRYGRRPLLILSLIGTVCSLLLFGFANSLIW-----LFVGR 99

Query: 132 LPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITGHLVYA 191
           +    TG +++I     AY++D+++ K+R   +G++     + L +G       G L+  
Sbjct: 100 MFDGATGGNISI---AQAYVSDITTDKDRARGMGMVG----AALGLGFIAGPAIGALLSK 152

Query: 192 HTTVGKMMYVGATAAALGPIVAPLI 216
                  ++V A  A L  I+  ++
Sbjct: 153 DGNYQLPIFVAAGIAVLSLILTIVV 177


>UniRef50_A4WAA4 Cluster: General substrate transporter; n=2;
           Enterobacteriaceae|Rep: General substrate transporter -
           Enterobacter sp. 638
          Length = 441

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 11/89 (12%)

Query: 85  FLGSYSDKRGRKIVLLAGLLGKLYFSI-MITVNTMNDWPVEYVIYTAALPSALTGADLAI 143
           F+G  SDK GRK ++LAG  G + F+   + V    D      + +A L   L GA +A 
Sbjct: 306 FMGYLSDKFGRKPLMLAGCAGFILFTYPAMMVMARGD------MLSAILAMLLLGAFIAA 359

Query: 144 FAG-CFAYIADVSSVKNRTLRVGILDVTY 171
           F G C A +A++      ++R G + + Y
Sbjct: 360 FDGACSAAMAELFPT---SIRYGGMAIAY 385


>UniRef50_A3EQV7 Cluster: Permease of the major facilitator
           superfamily; n=1; Leptospirillum sp. Group II UBA|Rep:
           Permease of the major facilitator superfamily -
           Leptospirillum sp. Group II UBA
          Length = 459

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 16/146 (10%)

Query: 70  WNGIASHVVPLFLAFF---LGSYSDKRGRKIVLLAGLLGKLYFSIMITVNTMNDWPVEYV 126
           W G+A     L  A F    G  SDK GRK V+  GL+  ++F   +     +       
Sbjct: 49  WLGLALGGYGLTQALFQVPFGMLSDKLGRKPVIAMGLI--IFFLGSVVAAEAHS------ 100

Query: 127 IYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAIAHITG 186
           + T  L   L GA  AI +   A +AD++  + RT  +  + +    ++ +  A+  I G
Sbjct: 101 VETLFLGRLLQGAG-AIASVIIALMADLTREEVRTRAMAGIGM----SIGLAFAMGMIVG 155

Query: 187 HLVYAHTTVGKMMYVGATAAALGPIV 212
            +V AH  V  + ++ A  A L  ++
Sbjct: 156 PIVGAHWDVSVLFWMTAALALLSLVI 181


>UniRef50_A0K0Q4 Cluster: Major facilitator superfamily MFS_1; n=1;
           Arthrobacter sp. FB24|Rep: Major facilitator superfamily
           MFS_1 - Arthrobacter sp. (strain FB24)
          Length = 442

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 14/113 (12%)

Query: 60  VQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGK-----LYFSIMIT 114
           V V  ST   W  I  +V+ +     +  +SDK GR+ V + G+LG      +YFS++ T
Sbjct: 276 VGVPASTM-LWVSITGNVLAIATQPLMAWFSDKYGRRPVFITGVLGSGAMIFVYFSVIST 334

Query: 115 VNTMNDWPVEYVIYTAALPSALTGA-DLAIFAGCFAYIADVSSVKNRTLRVGI 166
            N      V  +  T+ L +A T A   AI+   F+ + +V  V+   + +G+
Sbjct: 335 GN------VPMIFLTSTLITAGTYAMSNAIYPAWFSELFNV-KVRYSGMAIGL 380


>UniRef50_A0GXY1 Cluster: Major facilitator superfamily MFS_1; n=1;
           Chloroflexus aggregans DSM 9485|Rep: Major facilitator
           superfamily MFS_1 - Chloroflexus aggregans DSM 9485
          Length = 402

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 77  VVPLFLAFFLGSYSDKRGRKIVLLAGLLGK-LYFSIMITVNTMNDWPVEYVIYTAALPSA 135
           ++ L  A  LG+ SD+ GR+ V+L  L G  L +S +   +++        +  AA+  A
Sbjct: 51  LMQLLAAPLLGALSDRVGRRPVILGCLFGSALAYSWLALADSLP-------LLAAAI--A 101

Query: 136 LTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTLPMGIAI 181
           L G   +      AYIADV+S   RT   G+L   +   L  G AI
Sbjct: 102 LGGVAGSSMPVAQAYIADVTSPTERTHGFGLLGAAFGLGLIGGAAI 147


>UniRef50_Q6ET95 Cluster: Tetracycline transporter protein-like;
           n=4; Magnoliophyta|Rep: Tetracycline transporter
           protein-like - Oryza sativa subsp. japonica (Rice)
          Length = 211

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 16/55 (29%), Positives = 30/55 (54%)

Query: 200 YVGATAAALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQI 254
           Y+ A    L   V P IR+  SK +  +E+G+A   +S + +  +I A +++T +
Sbjct: 103 YLSAVFIILSAFVHPSIRTNVSKSVGSNEQGIAQGCISGISSFASILAPLIFTPL 157


>UniRef50_Q7SFA1 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 589

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 3/121 (2%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGK-LYFSIMITVNT 117
           +VQ  ++T   W      +  + +    G  SDK GR+ VL   LLG  L    + T+  
Sbjct: 163 DVQSYLATLQGWQATFDCIPSILMTVPFGILSDKWGRRPVLALALLGSMLQMFALSTIPR 222

Query: 118 MNDWPV--EYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRTLRVGILDVTYLSTL 175
           M   P+    +I +  +P  L+   + + A       +   +K +      LD   +ST 
Sbjct: 223 MISGPIAGSLMITSPWIPLVLSLGLMTLAAATTLVFPETRHLKAQASSTKRLDNEDISTY 282

Query: 176 P 176
           P
Sbjct: 283 P 283


>UniRef50_A4R5W6 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 506

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 4/44 (9%)

Query: 220 TSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEY 263
           TS   P  +R VAYAF++ M N  +I+AS      Y AT G +Y
Sbjct: 399 TSLPRPSAKRAVAYAFVNAMSNLASIYAS----YFYPATQGPQY 438


>UniRef50_A2R6P9 Cluster: Contig An16c0020, complete genome; n=1;
           Aspergillus niger|Rep: Contig An16c0020, complete genome
           - Aspergillus niger
          Length = 499

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 7/106 (6%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV--- 115
           EVQ  ++  + W  +   +  + LA   G  +D+ GRK +LL  L G L   + I V   
Sbjct: 93  EVQAELALVNGWKDMFDQLPGILLALPYGFLADRVGRKPILLLSLTGLLMEELAIRVVCW 152

Query: 116 -NTMNDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNR 160
            NT+   P+  V  T        G  L+  A  +A I D+  V  R
Sbjct: 153 CNTV--LPLRTVWVTPIFQLVGGGPQLST-AMAYAMITDLVPVSKR 195


>UniRef50_A1DAV5 Cluster: MFS transporter, putative; n=10;
           Pezizomycotina|Rep: MFS transporter, putative -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 832

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 16/57 (28%), Positives = 30/57 (52%)

Query: 59  EVQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMITV 115
           +VQ  ++  + W      +  +FLA   G  +D+ GRK VL+  L+G +   +M+ +
Sbjct: 88  DVQGELAFVNGWKQTLDTLPGIFLALPFGLMADQAGRKKVLMLSLIGLIMEEVMVRI 144


>UniRef50_A1CV39 Cluster: MFS transporter, putative; n=1;
           Neosartorya fischeri NRRL 181|Rep: MFS transporter,
           putative - Neosartorya fischeri (strain ATCC 1020 / DSM
           3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
           1020 / DSM 3700 / NRRL 181))
          Length = 440

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 4/110 (3%)

Query: 55  DINKE-VQVTVSTFHQWNGIASHVVPLFLAFFLGSYSDKRGRKIVLLAGLLGKLYFSIMI 113
           D  +E VQ  ++    W      +  +FLA   G  +DKRGRK V +    G L     +
Sbjct: 31  DCKREAVQSELALVQGWGDSLIQIPGIFLALPYGILADKRGRKPVFMLSFFGVLLSDTWV 90

Query: 114 TVNTM--NDWPVEYVIYTAALPSALTGADLAIFAGCFAYIADVSSVKNRT 161
            +  +  + +P+  +++ A +   + G         +  IADV+    RT
Sbjct: 91  KIVYLFPDIFPIR-MVWAAPVLQVIGGGRAVGTLLTYTIIADVAPRAERT 139


>UniRef50_Q9HLK4 Cluster: Self-defense gene tcr3 related protein;
           n=8; Archaea|Rep: Self-defense gene tcr3 related protein
           - Thermoplasma acidophilum
          Length = 486

 Score = 33.1 bits (72), Expect = 8.2
 Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 206 AALGPIVAPLIRSITSKLLPPDERGVAYAFLSVMENAVAIFASIVYTQIYNATIGTEYIN 265
           AA G ++     SI +   PP+ RG AY + SV  N+ A    IV   I    IG  Y  
Sbjct: 111 AAGGSMMQANSGSIIADNFPPNLRGRAYGYTSVGWNSGATL-GIVLGGIITTLIGWRY-- 167

Query: 266 SIFYFTISTQVIVFLSAL 283
            IFY  +   +I F  A+
Sbjct: 168 -IFYINVPIGIISFYFAM 184


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.327    0.138    0.414 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 280,976,938
Number of Sequences: 1657284
Number of extensions: 10871297
Number of successful extensions: 38560
Number of sequences better than 10.0: 198
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 38275
Number of HSP's gapped (non-prelim): 294
length of query: 283
length of database: 575,637,011
effective HSP length: 100
effective length of query: 183
effective length of database: 409,908,611
effective search space: 75013275813
effective search space used: 75013275813
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 72 (33.1 bits)

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