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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000667-TA|BGIBMGA000667-
PA|IPR004825|Insulin/IGF/relaxin, IPR004824|Bombyxin,
IPR003234|Insulin-related peptide
         (131 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyx...    60   1e-08
UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contain...    52   3e-06
UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contai...    46   2e-04
UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11) (4K-p...    46   3e-04
UniRef50_Q9I8Q7 Cluster: Preproinsulin; n=6; Tetrapoda|Rep: Prep...    45   6e-04
UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila pseudoobscu...    44   0.001
UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP precu...    43   0.002
UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contai...    43   0.002
UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B ...    42   0.003
UniRef50_P01327 Cluster: Insulin precursor [Contains: Insulin B ...    42   0.005
UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2) (4K-pro...    39   0.028
UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes aegy...    38   0.064
UniRef50_P01342 Cluster: Insulin precursor [Contains: Insulin B ...    38   0.064
UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor (A...    38   0.064
UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1; ...    37   0.11 
UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B ...    37   0.11 
UniRef50_P01308 Cluster: Insulin precursor [Contains: Insulin B ...    36   0.19 
UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4; ...    36   0.26 
UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precurs...    36   0.34 
UniRef50_Q8KJU8 Cluster: Putative uncharacterized protein orf280...    35   0.59 
UniRef50_P01315 Cluster: Insulin precursor [Contains: Insulin B ...    35   0.59 
UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep: ...    34   1.0  
UniRef50_Q4AAW3 Cluster: ATP synthase A chain; n=5; Mycoplasma h...    33   1.4  
UniRef50_Q31GQ6 Cluster: Beta-lactamase family protein precursor...    33   1.8  
UniRef50_P68988 Cluster: Insulin [Contains: Insulin B chain; Ins...    33   1.8  
UniRef50_A6G8V5 Cluster: Putative uncharacterized protein; n=1; ...    33   2.4  
UniRef50_A6D3W3 Cluster: Ig-like repeat domain protein 1; n=1; V...    33   2.4  
UniRef50_Q014P6 Cluster: [BT] KOG2132 Uncharacterized conserved ...    33   2.4  
UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes aegy...    33   2.4  
UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-li...    32   3.2  
UniRef50_Q6VVH0 Cluster: Insulin-like peptide 2 precursor; n=4; ...    32   3.2  
UniRef50_P67971 Cluster: Insulin [Contains: Insulin B chain; Ins...    32   3.2  
UniRef50_A3WI78 Cluster: Sensor protein; n=1; Erythrobacter sp. ...    32   4.2  
UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia californic...    32   4.2  
UniRef50_A1HR85 Cluster: Glycosyl transferase, family 2; n=1; Th...    31   5.5  
UniRef50_Q5MGP2 Cluster: Hormone peptide 1 Bombyxin-related pept...    31   5.5  
UniRef50_UPI00015B5A55 Cluster: PREDICTED: similar to MGC52894 p...    31   7.3  
UniRef50_UPI0000660636 Cluster: projection protein PF6; n=1; Tak...    31   7.3  
UniRef50_A5NVB0 Cluster: Sensor protein; n=5; Proteobacteria|Rep...    31   7.3  
UniRef50_P13190 Cluster: Insulin [Contains: Insulin B chain; Ins...    31   7.3  
UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-li...    31   9.6  
UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn...    31   9.6  
UniRef50_A0QG16 Cluster: Lipid-transfer protein; n=4; Actinomyce...    31   9.6  
UniRef50_P67973 Cluster: Insulin [Contains: Insulin B chain; Ins...    31   9.6  

>UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyxin
           IV) (4K-prothoracicotropic hormone IV) (4K-PTTH-IV)
           [Contains: Bombyxin E-1 B chain; Bombyxin E-1 A chain];
           n=1; Bombyx mori|Rep: Bombyxin E-1 precursor (BBX-E1)
           (Bombyxin IV) (4K-prothoracicotropic hormone IV)
           (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin
           E-1 A chain] - Bombyx mori (Silk moth)
          Length = 98

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 39/83 (46%), Positives = 47/83 (56%), Gaps = 13/83 (15%)

Query: 50  YCGRHLANARMVLCYDT-VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSK 108
           YCGRHLAN    LC+DT VEKR++S L A+  S G    WP L +     RA       K
Sbjct: 28  YCGRHLANTLADLCWDTSVEKRSESSL-ASYSSRG----WPWLPTPNFNKRAI-----KK 77

Query: 109 RGPGLVDECCLKPCYTYDLLNYC 131
           R  G+VDECC++PC    L  YC
Sbjct: 78  R--GVVDECCIQPCTLDVLATYC 98


>UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contains:
           Bombyxin A-2 homolog B chain; Bombyxin A-2 homolog A
           chain]; n=3; Samia cynthia|Rep: Bombyxin A-2 homolog
           precursor [Contains: Bombyxin A-2 homolog B chain;
           Bombyxin A-2 homolog A chain] - Samia cynthia (Cynthia
           moth) (Ailanthus silkmoth)
          Length = 100

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 37/107 (34%), Positives = 48/107 (44%), Gaps = 15/107 (14%)

Query: 25  FLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGD 84
           FLIVV  V A   D          VYCGR LA   + +C +  + +   Y+ +     G 
Sbjct: 7   FLIVVLAVMASGDD-------TAHVYCGRRLATMLLYVCDNQYQVKRPPYISSENEGYG- 58

Query: 85  LSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
              W  L  Q    RA  L E   +  G+V+ECC KPC   +LL YC
Sbjct: 59  ---WKWLERQ----RARQLDEARGKRQGIVEECCNKPCTENELLGYC 98


>UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contains:
           Bombyxin F-1 B chain; Bombyxin F-1 A chain]; n=2; Bombyx
           mori|Rep: Bombyxin F-1 precursor (BBX-F1) [Contains:
           Bombyxin F-1 B chain; Bombyxin F-1 A chain] - Bombyx
           mori (Silk moth)
          Length = 95

 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 17/112 (15%)

Query: 20  MFLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANI 79
           M L+  +++V  VS  V  +EL      R YCGRHLA    VLC+   E  A+     N 
Sbjct: 1   MKLVVIVLLVISVSILVSAQELG---GSRRYCGRHLAQTMAVLCWGIDEMSAEK---RNS 54

Query: 80  ISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
               + S  P L           L   +++  G++DECCL+ C    LL+YC
Sbjct: 55  DMVYEDSGMPEL-----------LPADTRKKRGIIDECCLQACTRDVLLSYC 95


>UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin B-11 B chain; Bombyxin B-11 A chain]; n=12;
           Bombyx mori|Rep: Bombyxin B-11 precursor (BBX-B11)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin B-11 B chain; Bombyxin B-11 A chain] - Bombyx
           mori (Silk moth)
          Length = 93

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 25/96 (26%)

Query: 27  IVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLS 86
           I+V ++S     +E   +E  R YCGRHLAN    +C+  VEKR            G   
Sbjct: 9   ILVVVISLTYSSEE---QEVARTYCGRHLANILAYVCFG-VEKR------------GGAQ 52

Query: 87  SWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPC 122
             P     Y ++R         +GPG+VDECC +PC
Sbjct: 53  YAPYWQETYLRSR---------KGPGVVDECCFRPC 79


>UniRef50_Q9I8Q7 Cluster: Preproinsulin; n=6; Tetrapoda|Rep:
           Preproinsulin - Rana pipiens (Northern leopard frog)
          Length = 106

 Score = 44.8 bits (101), Expect = 6e-04
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 12/94 (12%)

Query: 41  LKIEENPRVYCGRHLANARMVLCYDT---VEKRAQSYLDANIISAGDLSSWPGLSSQYAK 97
           LK  +N +  CG HL  A  ++C D       R++  L+  +++    S    L     +
Sbjct: 21  LKTFDN-QYLCGSHLVEALYMVCGDRGFFYSPRSRRDLEQPLVNGLQGSE---LDEMQVQ 76

Query: 98  TRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
           ++AF      KR PG+V++CC   C  YDL NYC
Sbjct: 77  SQAF-----QKRKPGIVEQCCHNTCSLYDLENYC 105


>UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila
           pseudoobscura|Rep: GA12803-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 102

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 11/98 (11%)

Query: 42  KIEENPRVYCGRHLANARMVLC---YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYA-- 96
           ++++     CG+ L++A  V+C   Y+T+ ++  S +DA    A + +  P L+S Y   
Sbjct: 5   QLQQGSHKLCGQALSDAMDVVCAHGYNTLPQKKSSTVDAQDDDAPEYALSPLLTSLYGAE 64

Query: 97  ---KTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
              KTR      + +   G+ DECC+  C   +L +YC
Sbjct: 65  VLIKTRRH---RRQRSSGGIYDECCVYSCRYEELASYC 99


>UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP
           precursor (Locusta insulin-related peptide); n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to LIRP
           precursor (Locusta insulin-related peptide) - Nasonia
           vitripennis
          Length = 136

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 21  FLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLC---YDTVEKRAQSY--- 74
           F +  L+ +    +DV+  E K  +    YCG+ L+NA  ++C   Y+ + K++      
Sbjct: 17  FAILLLLQLVQAQSDVYQYEQK-RQGASKYCGQQLSNALQLVCHGRYNPMFKKSVGQGME 75

Query: 75  LDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
           +D    +  D   +   +   A    F      +   G+ DECCLK C   ++ +YC
Sbjct: 76  MDDYPFNYDDSYPFRSRAVANAMMGRFGAGRFRRDSRGVHDECCLKSCTMNEMRSYC 132


>UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contains:
           Bombyxin G-1 B chain; Bombyxin G-1 A chain]; n=2; Bombyx
           mori|Rep: Bombyxin G-1 precursor (BBX-G1) [Contains:
           Bombyxin G-1 B chain; Bombyxin G-1 A chain] - Bombyx
           mori (Silk moth)
          Length = 90

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 20/107 (18%)

Query: 26  LIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDT-VEKRAQSYLDANIISAGD 84
           LI+  +    ++      +E  R YCGRHLA     LC+    +KR   Y   +      
Sbjct: 3   LIIFVVFCITIYGSTSGQQEVARRYCGRHLAVTMADLCFGVQFDKRNTQYEGYH------ 56

Query: 85  LSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
              WP L+  Y++       E+ KR  G+ DECCL PC T  L +YC
Sbjct: 57  ---WPLLA--YSE-------ERIKR-QGIADECCLVPCTTNVLSSYC 90


>UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=19; Teleostei|Rep: Insulin
           precursor [Contains: Insulin B chain; Insulin A chain] -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 108

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 47  PRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEK 106
           P+  CG HL +A  ++C  T       + +        L   P  S+Q  +   FA  + 
Sbjct: 26  PQHLCGSHLVDALYLVCGPT-----GFFYNPKRDVEPLLGFLPPKSAQETEVADFAFKDH 80

Query: 107 SK--RGPGLVDECCLKPCYTYDLLNYC 131
           ++  R  G+V++CC KPC  ++L NYC
Sbjct: 81  AELIRKRGIVEQCCHKPCSIFELQNYC 107


>UniRef50_P01327 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=1; Chinchilla
           brevicaudata|Rep: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain] - Chinchilla brevicaudata
           (Chinchilla)
          Length = 86

 Score = 41.5 bits (93), Expect = 0.005
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 51  CGRHLANARMVLCYDT---VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKS 107
           CG HL +A  ++C D        A   L+   +   D    PG+  +  + +  AL E +
Sbjct: 7   CGSHLVDALYLVCGDRGFFYTPMAXXELEDPQVGQAD----PGVVPEAGRLQPLAL-EMT 61

Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131
            +  G+VD+CC   C  Y L NYC
Sbjct: 62  LQXXGIVDQCCTSICTLYQLENYC 85


>UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin C-2 B chain; Bombyxin C-2 A chain]; n=12;
           Bombyx mori|Rep: Bombyxin C-2 precursor (BBX-C2)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin C-2 B chain; Bombyxin C-2 A chain] - Bombyx
           mori (Silk moth)
          Length = 95

 Score = 39.1 bits (87), Expect = 0.028
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 18/82 (21%)

Query: 50  YCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKR 109
           YCG  LA    +LC+  + KR+ S        AG    WP L         F+ + + KR
Sbjct: 26  YCGDFLARTMSILCWPDMPKRSGSQY------AG--YGWPWLP-------PFS-SSRGKR 69

Query: 110 GPGLVDECCLKPCYTYDLLNYC 131
             G+VDECC +PC T  L  YC
Sbjct: 70  --GIVDECCYRPCTTDVLKLYC 89


>UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes
           aegypti|Rep: Insulin-like peptide 2 - Aedes aegypti
           (Yellowfever mosquito)
          Length = 167

 Score = 37.9 bits (84), Expect = 0.064
 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%)

Query: 90  GLSSQYAKTRAFALAEKSKRGP-GLVDECCLKPCYTYDLLNYC 131
           G   + + +R   +  + ++ P G+VDECCL+PC    LL YC
Sbjct: 121 GYGFRSSASRNDLIPPRFRKSPRGIVDECCLRPCSINQLLKYC 163


>UniRef50_P01342 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=1; Myxine glutinosa|Rep:
           Insulin precursor [Contains: Insulin B chain; Insulin A
           chain] - Myxine glutinosa (Atlantic hagfish)
          Length = 115

 Score = 37.9 bits (84), Expect = 0.064
 Identities = 32/88 (36%), Positives = 41/88 (46%), Gaps = 13/88 (14%)

Query: 51  CGRHLANARMVLC------YD-TVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFAL 103
           CG+ L NA  + C      YD T  KR    L A +     L+      SQ  ++     
Sbjct: 33  CGKDLVNALYIACGVRGFFYDPTKMKRDTGALAAFL----PLAYAEDNESQDDESIGINE 88

Query: 104 AEKSKRGPGLVDECCLKPCYTYDLLNYC 131
             KSKRG  +V++CC K C  YDL NYC
Sbjct: 89  VLKSKRG--IVEQCCHKRCSIYDLENYC 114


>UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor
           (ABRP) [Contains: Bombyxin- related peptide A chain B;
           Bombyxin-related peptide A chain A]; n=5;
           Obtectomera|Rep: Bombyxin-related peptide A precursor
           (ABRP) [Contains: Bombyxin- related peptide A chain B;
           Bombyxin-related peptide A chain A] - Agrius convolvuli
           (Morning glory sphinx moth)
          Length = 103

 Score = 37.9 bits (84), Expect = 0.064
 Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 21/114 (18%)

Query: 22  LLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLC----YDTVEKRAQSYLDA 77
           L  F  V +L +A    +E +I+      CGRHLA     LC    Y+ V KR+ +   A
Sbjct: 7   LCCFFAVYSLAAAQGGQEEFQIKVR---ICGRHLARTLADLCPNVEYEDVMKRSGARSPA 63

Query: 78  NIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131
              + G    WP     +A+  A     + KR  G+ D+CC+  C    LL+YC
Sbjct: 64  LYGTVG----WP-----WARPGA----ARGKRA-GVADDCCVNSCTMDVLLSYC 103


>UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 161

 Score = 37.1 bits (82), Expect = 0.11
 Identities = 15/27 (55%), Positives = 19/27 (70%), Gaps = 1/27 (3%)

Query: 106 KSKRGPGLVDECCLKPC-YTYDLLNYC 131
           K + G G+V+ECC K C Y Y +LNYC
Sbjct: 134 KRRPGKGIVEECCRKGCTYEYLMLNYC 160


>UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=8; Elopocephala|Rep: Insulin
           precursor [Contains: Insulin B chain; Insulin A chain] -
           Oncorhynchus keta (Chum salmon)
          Length = 105

 Score = 37.1 bits (82), Expect = 0.11
 Identities = 12/20 (60%), Positives = 16/20 (80%)

Query: 112 GLVDECCLKPCYTYDLLNYC 131
           G+V++CC KPC  +DL NYC
Sbjct: 85  GIVEQCCHKPCNIFDLQNYC 104


>UniRef50_P01308 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=85; Gnathostomata|Rep:
           Insulin precursor [Contains: Insulin B chain; Insulin A
           chain] - Homo sapiens (Human)
          Length = 110

 Score = 36.3 bits (80), Expect = 0.19
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 51  CGRHLANARMVLCYDT-VEKRAQSYLDANIISAG--DLSSWPGLSSQYAKTRAFALAEKS 107
           CG HL  A  ++C +       ++  +A  +  G  +L   PG  S     +  AL E S
Sbjct: 31  CGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGS----LQPLAL-EGS 85

Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131
            +  G+V++CC   C  Y L NYC
Sbjct: 86  LQKRGIVEQCCTSICSLYQLENYC 109


>UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4;
           Anopheles gambiae|Rep: Insulin-like peptide 3 precursor
           - Anopheles gambiae (African malaria mosquito)
          Length = 160

 Score = 35.9 bits (79), Expect = 0.26
 Identities = 14/26 (53%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 106 KSKRGPGLVDECCLKPCYTYDLLNYC 131
           +  RG G+V+ECCL+PC    LL YC
Sbjct: 130 RKNRG-GIVEECCLRPCGMNQLLQYC 154


>UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precursor
           (Insulin-related peptide) (DILP3) [Contains: Probable
           insulin-like peptide 3 A chain; Probable insulin-like
           peptide 3 B chain]; n=3; Drosophila melanogaster|Rep:
           Probable insulin-like peptide 3 precursor
           (Insulin-related peptide) (DILP3) [Contains: Probable
           insulin-like peptide 3 A chain; Probable insulin-like
           peptide 3 B chain] - Drosophila melanogaster (Fruit fly)
          Length = 120

 Score = 35.5 bits (78), Expect = 0.34
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 51  CGRHLANARMVLC---YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKS 107
           CGR L      LC   ++ + KR    ++ N I   +  S   L  +     +  + +  
Sbjct: 34  CGRKLPETLSKLCVYGFNAMTKRTLDPVNFNQIDGFEDRS---LLERLLSDSSVQMLKTR 90

Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131
           +   G+ DECCLK C   ++L YC
Sbjct: 91  RLRDGVFDECCLKSCTMDEVLRYC 114


>UniRef50_Q8KJU8 Cluster: Putative uncharacterized protein orf280;
           n=1; Proteus vulgaris|Rep: Putative uncharacterized
           protein orf280 - Proteus vulgaris
          Length = 93

 Score = 34.7 bits (76), Expect = 0.59
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 51  CGRHLANARMVLCYDTVEKRAQSYLDAN--IISAGDLSSWPGLSSQYAKTRAFALAE 105
           C  ++A A +V    TV++R+   LD N  + + GD S W G S  Y   +  A  E
Sbjct: 28  CSAYVAEADLVKACKTVQRRSPDSLDGNKELTNEGDPSVWIGWSGDYRTPQQLAAIE 84


>UniRef50_P01315 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=12; Eukaryota|Rep: Insulin
           precursor [Contains: Insulin B chain; Insulin A chain] -
           Sus scrofa (Pig)
          Length = 108

 Score = 34.7 bits (76), Expect = 0.59
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 51  CGRHLANARMVLCYDT-VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKR 109
           CG HL  A  ++C +       ++  +A    AG +    GL       +A AL E   +
Sbjct: 31  CGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGGGLGG----LQALAL-EGPPQ 85

Query: 110 GPGLVDECCLKPCYTYDLLNYC 131
             G+V++CC   C  Y L NYC
Sbjct: 86  KRGIVEQCCTSICSLYQLENYC 107


>UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep:
           Preproinsulin 2 - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 107

 Score = 33.9 bits (74), Expect = 1.0
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)

Query: 95  YAKTRAFALAEK-SKRGPGLVDECCLKPCYTYDLLNYC 131
           Y    A  L EK  K   G+V++CC +PC  Y L +YC
Sbjct: 69  YEAADADPLKEKVMKMKRGIVEQCCHRPCTIYHLEDYC 106


>UniRef50_Q4AAW3 Cluster: ATP synthase A chain; n=5; Mycoplasma
          hyopneumoniae|Rep: ATP synthase A chain - Mycoplasma
          hyopneumoniae (strain J / ATCC 25934 / NCTC 10110)
          Length = 242

 Score = 33.5 bits (73), Expect = 1.4
 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 18 FKMFLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLD 76
          F +F+L FL+++  +    H K+ KI+E+P        A + ++   D VE   + Y++
Sbjct: 13 FTLFILVFLVIILSIIIFFHIKKAKIDESPSAVV--LFAESYLIFIDDLVETAGEGYIN 69


>UniRef50_Q31GQ6 Cluster: Beta-lactamase family protein precursor;
           n=1; Thiomicrospira crunogena XCL-2|Rep: Beta-lactamase
           family protein precursor - Thiomicrospira crunogena
           (strain XCL-2)
          Length = 412

 Score = 33.1 bits (72), Expect = 1.8
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 64  YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKT-RAFALAEKSKRGPGLV 114
           YD +EKR    LD    S  D    PGL++ Y +   AF    KS +G  ++
Sbjct: 226 YDQIEKRFLIPLDLTFTSPADRRKLPGLATGYTRADNAFGFPVKSTKGKAVM 277


>UniRef50_P68988 Cluster: Insulin [Contains: Insulin B chain;
           Insulin A chain]; n=14; Vertebrata|Rep: Insulin
           [Contains: Insulin B chain; Insulin A chain] - Lampetra
           fluviatilis (River lamprey)
          Length = 57

 Score = 33.1 bits (72), Expect = 1.8
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 112 GLVDECCLKPCYTYDLLNYC 131
           G+V++CC + C  YD+ NYC
Sbjct: 37  GIVEQCCHRKCSIYDMENYC 56


>UniRef50_A6G8V5 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 257

 Score = 32.7 bits (71), Expect = 2.4
 Identities = 15/47 (31%), Positives = 22/47 (46%)

Query: 77  ANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCY 123
           A++++A   S+W  LS  Y    A   A   +RG G    C   PC+
Sbjct: 4   ASLVAAAPPSTWAVLSLAYVGVGAVVAAHLGRRGHGFGTACAALPCW 50


>UniRef50_A6D3W3 Cluster: Ig-like repeat domain protein 1; n=1;
           Vibrio shilonii AK1|Rep: Ig-like repeat domain protein 1
           - Vibrio shilonii AK1
          Length = 1381

 Score = 32.7 bits (71), Expect = 2.4
 Identities = 16/54 (29%), Positives = 25/54 (46%)

Query: 74  YLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDL 127
           Y D +      LSSW   ++  A   AF +A+  ++G   +  C L  C T +L
Sbjct: 524 YSDGSKRDVSTLSSWQSNNTDIATINAFGVAQGEEQGTSQISGCYLGQCATANL 577


>UniRef50_Q014P6 Cluster: [BT] KOG2132 Uncharacterized conserved
           protein; n=2; Ostreococcus|Rep: [BT] KOG2132
           Uncharacterized conserved protein - Ostreococcus tauri
          Length = 275

 Score = 32.7 bits (71), Expect = 2.4
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 38  DKELKIEENPRVYCGRHL-ANARMV--LCYDTVEKRAQSYLDANIIS-AGDLSSWPGLSS 93
           ++ LK+E++ R +   H  A  R+   LC D    R  S++D      AG  S    LSS
Sbjct: 21  EQRLKLEDDARAFARDHRGARPRLFTGLCADVPAVR--SWMDVEAFERAGAGSRTCTLSS 78

Query: 94  QYAKTRAFALAEKSKRGPGLVDECCLK 120
           + A  RAF  A+  K   G  +E C K
Sbjct: 79  RAADGRAFIKADCEKDESGTFEEACEK 105


>UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes
           aegypti|Rep: Insulin-like peptide 7 - Aedes aegypti
           (Yellowfever mosquito)
          Length = 160

 Score = 32.7 bits (71), Expect = 2.4
 Identities = 13/21 (61%), Positives = 15/21 (71%), Gaps = 1/21 (4%)

Query: 112 GLVDECCLKPC-YTYDLLNYC 131
           G+VD+CC KPC   Y L NYC
Sbjct: 139 GVVDDCCYKPCTLQYLLKNYC 159


>UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-like
           peptide 3 CG14167-PA; n=1; Apis mellifera|Rep:
           PREDICTED: similar to insulin-like peptide 3 CG14167-PA
           - Apis mellifera
          Length = 73

 Score = 32.3 bits (70), Expect = 3.2
 Identities = 11/24 (45%), Positives = 16/24 (66%)

Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131
           +   G+ +ECCLK C T +L +YC
Sbjct: 47  RNSKGIHEECCLKSCTTEELRSYC 70


>UniRef50_Q6VVH0 Cluster: Insulin-like peptide 2 precursor; n=4;
           Culicidae|Rep: Insulin-like peptide 2 precursor -
           Anopheles gambiae (African malaria mosquito)
          Length = 134

 Score = 32.3 bits (70), Expect = 3.2
 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 6/88 (6%)

Query: 50  YCGRHLANARMVLC---YDTVEKRAQSYL--DANIISAGDLSSWPGLSSQYAKTRAFALA 104
           YCGR L      LC   Y  +      Y+   AN     ++++ P             + 
Sbjct: 46  YCGRRLTETLAFLCQGRYPMLTHYRTDYVHDQANQRVKVEVATLPDTLPPGFPYPGAGVH 105

Query: 105 EKSKRGPG-LVDECCLKPCYTYDLLNYC 131
            +S+R  G + DECC K C   +L  YC
Sbjct: 106 RRSRRSSGGIYDECCKKSCSYVELRAYC 133


>UniRef50_P67971 Cluster: Insulin [Contains: Insulin B chain;
           Insulin A chain]; n=7; Euteleostomi|Rep: Insulin
           [Contains: Insulin B chain; Insulin A chain] - Saimiri
           sciureus (Common squirrel monkey)
          Length = 51

 Score = 32.3 bits (70), Expect = 3.2
 Identities = 11/20 (55%), Positives = 13/20 (65%)

Query: 112 GLVDECCLKPCYTYDLLNYC 131
           G+VD+CC   C  Y L NYC
Sbjct: 31  GVVDQCCTSICSLYQLQNYC 50


>UniRef50_A3WI78 Cluster: Sensor protein; n=1; Erythrobacter sp.
           NAP1|Rep: Sensor protein - Erythrobacter sp. NAP1
          Length = 418

 Score = 31.9 bits (69), Expect = 4.2
 Identities = 11/33 (33%), Positives = 23/33 (69%)

Query: 76  DANIISAGDLSSWPGLSSQYAKTRAFALAEKSK 108
           +A  + AGD++SWPGL ++ ++    A+ ++S+
Sbjct: 68  NAGNVIAGDIASWPGLDARVSEAGVIAIGDQSE 100


>UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia
           californica|Rep: Insulin-like 0 - Aplysia californica
           (California sea hare)
          Length = 262

 Score = 31.9 bits (69), Expect = 4.2
 Identities = 11/19 (57%), Positives = 14/19 (73%)

Query: 113 LVDECCLKPCYTYDLLNYC 131
           +VDECCL+PC    L +YC
Sbjct: 171 IVDECCLRPCNFATLQSYC 189


>UniRef50_A1HR85 Cluster: Glycosyl transferase, family 2; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Glycosyl
           transferase, family 2 - Thermosinus carboxydivorans Nor1
          Length = 479

 Score = 31.5 bits (68), Expect = 5.5
 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 1   MTLFGATKAIQEKIMPTFKMFLLYFLIVVALVSADVHDKELKIEENPRVY 50
           M LFGA  A+ E I+P +K    Y+   + +V A  HD  ++ +E   +Y
Sbjct: 126 MLLFGAPLALSE-ILPFYKSIKEYYAGSITIVKASSHD--IEFDETDEIY 172


>UniRef50_Q5MGP2 Cluster: Hormone peptide 1 Bombyxin-related
           peptide; n=1; Lonomia obliqua|Rep: Hormone peptide 1
           Bombyxin-related peptide - Lonomia obliqua (Moth)
          Length = 96

 Score = 31.5 bits (68), Expect = 5.5
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 6/59 (10%)

Query: 79  IISAGDLSSWPGLSSQYAKTRAFAL-----AEKSKRGPG-LVDECCLKPCYTYDLLNYC 131
           I++  +L  +   +S+Y+KT+  +      A+   + P  +V+ECC+  C   D L YC
Sbjct: 38  IMALINLCGYEQTNSKYSKTKRSSANDDRDADADNKEPSSIVEECCINSCLLKDFLLYC 96


>UniRef50_UPI00015B5A55 Cluster: PREDICTED: similar to MGC52894
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC52894 protein - Nasonia vitripennis
          Length = 604

 Score = 31.1 bits (67), Expect = 7.3
 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 10  IQEKIMPTFKMFLLYFLIVVALVSADVHDKELKIEENPRV--YCGRHL-ANARMVLCYDT 66
           +QE ++    ++LL+ L++V +      DK+   E   RV   C + L A  R V  Y+ 
Sbjct: 431 LQEPLLVAVALYLLFLLVIVYVRLDFSIDKDEASESKLRVAGQCEKILAAQDRRVTSYNE 490

Query: 67  VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPG 112
           ++ +  +YL  N      LS   G++ +Y K    A+AE +++  G
Sbjct: 491 LDDQL-NYLKTNKDVNAYLSVVKGITQEY-KNATAAIAELAQKLKG 534


>UniRef50_UPI0000660636 Cluster: projection protein PF6; n=1;
           Takifugu rubripes|Rep: projection protein PF6 - Takifugu
           rubripes
          Length = 1694

 Score = 31.1 bits (67), Expect = 7.3
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 27  IVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLS 86
           +V    +  +H  E ++E   R++ G  +AN    L YD +E R Q     N I    + 
Sbjct: 280 VVQLSYTVQIHSPEAELETGIRIFGG--VAN----LLYDCLEWRRQHQHYLNNIRLIKVP 333

Query: 87  SWPGLSSQYAKTRAFALAEKSKR 109
            WP L  Q A+  A A     K+
Sbjct: 334 DWPRLPPQQAEQAAPATPRSKKK 356


>UniRef50_A5NVB0 Cluster: Sensor protein; n=5; Proteobacteria|Rep:
            Sensor protein - Methylobacterium sp. 4-46
          Length = 1165

 Score = 31.1 bits (67), Expect = 7.3
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 52   GRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGP 111
            GR LA+A  VL  D        Y +  ++ AGDL   PG+      T+ F L E ++R  
Sbjct: 1073 GRQLADAGRVLRPDLKVLFITGYAETTVVGAGDLQ--PGME---VLTKPFVLEELARRIR 1127

Query: 112  GLV 114
            G++
Sbjct: 1128 GMI 1130


>UniRef50_P13190 Cluster: Insulin [Contains: Insulin B chain;
           Insulin A chain]; n=3; Gnathostomata|Rep: Insulin
           [Contains: Insulin B chain; Insulin A chain] -
           Callorhynchus milii (Elephant shark) (Elephantfish)
          Length = 89

 Score = 31.1 bits (67), Expect = 7.3
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 9/86 (10%)

Query: 51  CGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSW----PGLSSQYAKTRAFALA-E 105
           CG HL +A   +C +    R   Y    I   G LS++    P L ++      +     
Sbjct: 7   CGSHLVDALYFVCGE----RGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQLA 62

Query: 106 KSKRGPGLVDECCLKPCYTYDLLNYC 131
            SK   G+V++CC   C   +L  YC
Sbjct: 63  GSKMKRGIVEQCCHNTCSLVNLEGYC 88


>UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-like
           growth factor-I; n=2; Danio rerio|Rep: PREDICTED:
           similar to insulin-like growth factor-I - Danio rerio
          Length = 188

 Score = 30.7 bits (66), Expect = 9.6
 Identities = 11/23 (47%), Positives = 15/23 (65%)

Query: 109 RGPGLVDECCLKPCYTYDLLNYC 131
           RG G+VD+CC++ C    L  YC
Sbjct: 81  RGKGIVDQCCVRGCDLQHLELYC 103


>UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin
            - Gallus gallus (Chicken)
          Length = 8074

 Score = 30.7 bits (66), Expect = 9.6
 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 40   ELKIEENPRVYCGRHLANARMVLCYDTVEKRAQ--SYLDANIISAGDLSSWPGLSSQY 95
            +L+ + N R+ CG H+A+AR+ +    VE+     ++ + N  +     S P   SQ+
Sbjct: 4689 QLEDQGNYRIVCGPHIASARLTVIEPAVERHLHDTTFKEGNTCTLSCQFSIPNAKSQW 4746


>UniRef50_A0QG16 Cluster: Lipid-transfer protein; n=4;
           Actinomycetales|Rep: Lipid-transfer protein -
           Mycobacterium avium (strain 104)
          Length = 378

 Score = 30.7 bits (66), Expect = 9.6
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 86  SSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLL 128
           S W   +  Y++T    + EK+   P  +D  C+  C+TY ++
Sbjct: 245 SEWDDPTEMYSRTAGPKIWEKTGLTPADMDVACMYDCFTYTVM 287


>UniRef50_P67973 Cluster: Insulin [Contains: Insulin B chain;
           Insulin A chain]; n=28; cellular organisms|Rep: Insulin
           [Contains: Insulin B chain; Insulin A chain] -
           Balaenoptera physalus (Finback whale) (Common rorqual)
          Length = 51

 Score = 30.7 bits (66), Expect = 9.6
 Identities = 10/20 (50%), Positives = 13/20 (65%)

Query: 112 GLVDECCLKPCYTYDLLNYC 131
           G+V++CC   C  Y L NYC
Sbjct: 31  GIVEQCCTSICSLYQLENYC 50


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.324    0.137    0.418 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,965,028
Number of Sequences: 1657284
Number of extensions: 4695667
Number of successful extensions: 12703
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 12662
Number of HSP's gapped (non-prelim): 50
length of query: 131
length of database: 575,637,011
effective HSP length: 92
effective length of query: 39
effective length of database: 423,166,883
effective search space: 16503508437
effective search space used: 16503508437
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 66 (30.7 bits)

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