BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000667-TA|BGIBMGA000667- PA|IPR004825|Insulin/IGF/relaxin, IPR004824|Bombyxin, IPR003234|Insulin-related peptide (131 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyx... 60 1e-08 UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contain... 52 3e-06 UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contai... 46 2e-04 UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11) (4K-p... 46 3e-04 UniRef50_Q9I8Q7 Cluster: Preproinsulin; n=6; Tetrapoda|Rep: Prep... 45 6e-04 UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila pseudoobscu... 44 0.001 UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP precu... 43 0.002 UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contai... 43 0.002 UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B ... 42 0.003 UniRef50_P01327 Cluster: Insulin precursor [Contains: Insulin B ... 42 0.005 UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2) (4K-pro... 39 0.028 UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes aegy... 38 0.064 UniRef50_P01342 Cluster: Insulin precursor [Contains: Insulin B ... 38 0.064 UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor (A... 38 0.064 UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1; ... 37 0.11 UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B ... 37 0.11 UniRef50_P01308 Cluster: Insulin precursor [Contains: Insulin B ... 36 0.19 UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4; ... 36 0.26 UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precurs... 36 0.34 UniRef50_Q8KJU8 Cluster: Putative uncharacterized protein orf280... 35 0.59 UniRef50_P01315 Cluster: Insulin precursor [Contains: Insulin B ... 35 0.59 UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep: ... 34 1.0 UniRef50_Q4AAW3 Cluster: ATP synthase A chain; n=5; Mycoplasma h... 33 1.4 UniRef50_Q31GQ6 Cluster: Beta-lactamase family protein precursor... 33 1.8 UniRef50_P68988 Cluster: Insulin [Contains: Insulin B chain; Ins... 33 1.8 UniRef50_A6G8V5 Cluster: Putative uncharacterized protein; n=1; ... 33 2.4 UniRef50_A6D3W3 Cluster: Ig-like repeat domain protein 1; n=1; V... 33 2.4 UniRef50_Q014P6 Cluster: [BT] KOG2132 Uncharacterized conserved ... 33 2.4 UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes aegy... 33 2.4 UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-li... 32 3.2 UniRef50_Q6VVH0 Cluster: Insulin-like peptide 2 precursor; n=4; ... 32 3.2 UniRef50_P67971 Cluster: Insulin [Contains: Insulin B chain; Ins... 32 3.2 UniRef50_A3WI78 Cluster: Sensor protein; n=1; Erythrobacter sp. ... 32 4.2 UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia californic... 32 4.2 UniRef50_A1HR85 Cluster: Glycosyl transferase, family 2; n=1; Th... 31 5.5 UniRef50_Q5MGP2 Cluster: Hormone peptide 1 Bombyxin-related pept... 31 5.5 UniRef50_UPI00015B5A55 Cluster: PREDICTED: similar to MGC52894 p... 31 7.3 UniRef50_UPI0000660636 Cluster: projection protein PF6; n=1; Tak... 31 7.3 UniRef50_A5NVB0 Cluster: Sensor protein; n=5; Proteobacteria|Rep... 31 7.3 UniRef50_P13190 Cluster: Insulin [Contains: Insulin B chain; Ins... 31 7.3 UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-li... 31 9.6 UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn... 31 9.6 UniRef50_A0QG16 Cluster: Lipid-transfer protein; n=4; Actinomyce... 31 9.6 UniRef50_P67973 Cluster: Insulin [Contains: Insulin B chain; Ins... 31 9.6 >UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyxin IV) (4K-prothoracicotropic hormone IV) (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin E-1 A chain]; n=1; Bombyx mori|Rep: Bombyxin E-1 precursor (BBX-E1) (Bombyxin IV) (4K-prothoracicotropic hormone IV) (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin E-1 A chain] - Bombyx mori (Silk moth) Length = 98 Score = 60.1 bits (139), Expect = 1e-08 Identities = 39/83 (46%), Positives = 47/83 (56%), Gaps = 13/83 (15%) Query: 50 YCGRHLANARMVLCYDT-VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSK 108 YCGRHLAN LC+DT VEKR++S L A+ S G WP L + RA K Sbjct: 28 YCGRHLANTLADLCWDTSVEKRSESSL-ASYSSRG----WPWLPTPNFNKRAI-----KK 77 Query: 109 RGPGLVDECCLKPCYTYDLLNYC 131 R G+VDECC++PC L YC Sbjct: 78 R--GVVDECCIQPCTLDVLATYC 98 >UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contains: Bombyxin A-2 homolog B chain; Bombyxin A-2 homolog A chain]; n=3; Samia cynthia|Rep: Bombyxin A-2 homolog precursor [Contains: Bombyxin A-2 homolog B chain; Bombyxin A-2 homolog A chain] - Samia cynthia (Cynthia moth) (Ailanthus silkmoth) Length = 100 Score = 52.4 bits (120), Expect = 3e-06 Identities = 37/107 (34%), Positives = 48/107 (44%), Gaps = 15/107 (14%) Query: 25 FLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGD 84 FLIVV V A D VYCGR LA + +C + + + Y+ + G Sbjct: 7 FLIVVLAVMASGDD-------TAHVYCGRRLATMLLYVCDNQYQVKRPPYISSENEGYG- 58 Query: 85 LSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 W L Q RA L E + G+V+ECC KPC +LL YC Sbjct: 59 ---WKWLERQ----RARQLDEARGKRQGIVEECCNKPCTENELLGYC 98 >UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contains: Bombyxin F-1 B chain; Bombyxin F-1 A chain]; n=2; Bombyx mori|Rep: Bombyxin F-1 precursor (BBX-F1) [Contains: Bombyxin F-1 B chain; Bombyxin F-1 A chain] - Bombyx mori (Silk moth) Length = 95 Score = 46.0 bits (104), Expect = 2e-04 Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 17/112 (15%) Query: 20 MFLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANI 79 M L+ +++V VS V +EL R YCGRHLA VLC+ E A+ N Sbjct: 1 MKLVVIVLLVISVSILVSAQELG---GSRRYCGRHLAQTMAVLCWGIDEMSAEK---RNS 54 Query: 80 ISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 + S P L L +++ G++DECCL+ C LL+YC Sbjct: 55 DMVYEDSGMPEL-----------LPADTRKKRGIIDECCLQACTRDVLLSYC 95 >UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11) (4K-prothoracicotropic hormone) (4K- PTTH) [Contains: Bombyxin B-11 B chain; Bombyxin B-11 A chain]; n=12; Bombyx mori|Rep: Bombyxin B-11 precursor (BBX-B11) (4K-prothoracicotropic hormone) (4K- PTTH) [Contains: Bombyxin B-11 B chain; Bombyxin B-11 A chain] - Bombyx mori (Silk moth) Length = 93 Score = 45.6 bits (103), Expect = 3e-04 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 25/96 (26%) Query: 27 IVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLS 86 I+V ++S +E +E R YCGRHLAN +C+ VEKR G Sbjct: 9 ILVVVISLTYSSEE---QEVARTYCGRHLANILAYVCFG-VEKR------------GGAQ 52 Query: 87 SWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPC 122 P Y ++R +GPG+VDECC +PC Sbjct: 53 YAPYWQETYLRSR---------KGPGVVDECCFRPC 79 >UniRef50_Q9I8Q7 Cluster: Preproinsulin; n=6; Tetrapoda|Rep: Preproinsulin - Rana pipiens (Northern leopard frog) Length = 106 Score = 44.8 bits (101), Expect = 6e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 12/94 (12%) Query: 41 LKIEENPRVYCGRHLANARMVLCYDT---VEKRAQSYLDANIISAGDLSSWPGLSSQYAK 97 LK +N + CG HL A ++C D R++ L+ +++ S L + Sbjct: 21 LKTFDN-QYLCGSHLVEALYMVCGDRGFFYSPRSRRDLEQPLVNGLQGSE---LDEMQVQ 76 Query: 98 TRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 ++AF KR PG+V++CC C YDL NYC Sbjct: 77 SQAF-----QKRKPGIVEQCCHNTCSLYDLENYC 105 >UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila pseudoobscura|Rep: GA12803-PA - Drosophila pseudoobscura (Fruit fly) Length = 102 Score = 44.0 bits (99), Expect = 0.001 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 11/98 (11%) Query: 42 KIEENPRVYCGRHLANARMVLC---YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYA-- 96 ++++ CG+ L++A V+C Y+T+ ++ S +DA A + + P L+S Y Sbjct: 5 QLQQGSHKLCGQALSDAMDVVCAHGYNTLPQKKSSTVDAQDDDAPEYALSPLLTSLYGAE 64 Query: 97 ---KTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 KTR + + G+ DECC+ C +L +YC Sbjct: 65 VLIKTRRH---RRQRSSGGIYDECCVYSCRYEELASYC 99 >UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP precursor (Locusta insulin-related peptide); n=1; Nasonia vitripennis|Rep: PREDICTED: similar to LIRP precursor (Locusta insulin-related peptide) - Nasonia vitripennis Length = 136 Score = 43.2 bits (97), Expect = 0.002 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 7/117 (5%) Query: 21 FLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLC---YDTVEKRAQSY--- 74 F + L+ + +DV+ E K + YCG+ L+NA ++C Y+ + K++ Sbjct: 17 FAILLLLQLVQAQSDVYQYEQK-RQGASKYCGQQLSNALQLVCHGRYNPMFKKSVGQGME 75 Query: 75 LDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 +D + D + + A F + G+ DECCLK C ++ +YC Sbjct: 76 MDDYPFNYDDSYPFRSRAVANAMMGRFGAGRFRRDSRGVHDECCLKSCTMNEMRSYC 132 >UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contains: Bombyxin G-1 B chain; Bombyxin G-1 A chain]; n=2; Bombyx mori|Rep: Bombyxin G-1 precursor (BBX-G1) [Contains: Bombyxin G-1 B chain; Bombyxin G-1 A chain] - Bombyx mori (Silk moth) Length = 90 Score = 43.2 bits (97), Expect = 0.002 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 20/107 (18%) Query: 26 LIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDT-VEKRAQSYLDANIISAGD 84 LI+ + ++ +E R YCGRHLA LC+ +KR Y + Sbjct: 3 LIIFVVFCITIYGSTSGQQEVARRYCGRHLAVTMADLCFGVQFDKRNTQYEGYH------ 56 Query: 85 LSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 WP L+ Y++ E+ KR G+ DECCL PC T L +YC Sbjct: 57 ---WPLLA--YSE-------ERIKR-QGIADECCLVPCTTNVLSSYC 90 >UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=19; Teleostei|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 108 Score = 42.3 bits (95), Expect = 0.003 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 47 PRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEK 106 P+ CG HL +A ++C T + + L P S+Q + FA + Sbjct: 26 PQHLCGSHLVDALYLVCGPT-----GFFYNPKRDVEPLLGFLPPKSAQETEVADFAFKDH 80 Query: 107 SK--RGPGLVDECCLKPCYTYDLLNYC 131 ++ R G+V++CC KPC ++L NYC Sbjct: 81 AELIRKRGIVEQCCHKPCSIFELQNYC 107 >UniRef50_P01327 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=1; Chinchilla brevicaudata|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Chinchilla brevicaudata (Chinchilla) Length = 86 Score = 41.5 bits (93), Expect = 0.005 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 51 CGRHLANARMVLCYDT---VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKS 107 CG HL +A ++C D A L+ + D PG+ + + + AL E + Sbjct: 7 CGSHLVDALYLVCGDRGFFYTPMAXXELEDPQVGQAD----PGVVPEAGRLQPLAL-EMT 61 Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131 + G+VD+CC C Y L NYC Sbjct: 62 LQXXGIVDQCCTSICTLYQLENYC 85 >UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2) (4K-prothoracicotropic hormone) (4K- PTTH) [Contains: Bombyxin C-2 B chain; Bombyxin C-2 A chain]; n=12; Bombyx mori|Rep: Bombyxin C-2 precursor (BBX-C2) (4K-prothoracicotropic hormone) (4K- PTTH) [Contains: Bombyxin C-2 B chain; Bombyxin C-2 A chain] - Bombyx mori (Silk moth) Length = 95 Score = 39.1 bits (87), Expect = 0.028 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 18/82 (21%) Query: 50 YCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKR 109 YCG LA +LC+ + KR+ S AG WP L F+ + + KR Sbjct: 26 YCGDFLARTMSILCWPDMPKRSGSQY------AG--YGWPWLP-------PFS-SSRGKR 69 Query: 110 GPGLVDECCLKPCYTYDLLNYC 131 G+VDECC +PC T L YC Sbjct: 70 --GIVDECCYRPCTTDVLKLYC 89 >UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes aegypti|Rep: Insulin-like peptide 2 - Aedes aegypti (Yellowfever mosquito) Length = 167 Score = 37.9 bits (84), Expect = 0.064 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Query: 90 GLSSQYAKTRAFALAEKSKRGP-GLVDECCLKPCYTYDLLNYC 131 G + + +R + + ++ P G+VDECCL+PC LL YC Sbjct: 121 GYGFRSSASRNDLIPPRFRKSPRGIVDECCLRPCSINQLLKYC 163 >UniRef50_P01342 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=1; Myxine glutinosa|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Myxine glutinosa (Atlantic hagfish) Length = 115 Score = 37.9 bits (84), Expect = 0.064 Identities = 32/88 (36%), Positives = 41/88 (46%), Gaps = 13/88 (14%) Query: 51 CGRHLANARMVLC------YD-TVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFAL 103 CG+ L NA + C YD T KR L A + L+ SQ ++ Sbjct: 33 CGKDLVNALYIACGVRGFFYDPTKMKRDTGALAAFL----PLAYAEDNESQDDESIGINE 88 Query: 104 AEKSKRGPGLVDECCLKPCYTYDLLNYC 131 KSKRG +V++CC K C YDL NYC Sbjct: 89 VLKSKRG--IVEQCCHKRCSIYDLENYC 114 >UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor (ABRP) [Contains: Bombyxin- related peptide A chain B; Bombyxin-related peptide A chain A]; n=5; Obtectomera|Rep: Bombyxin-related peptide A precursor (ABRP) [Contains: Bombyxin- related peptide A chain B; Bombyxin-related peptide A chain A] - Agrius convolvuli (Morning glory sphinx moth) Length = 103 Score = 37.9 bits (84), Expect = 0.064 Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 21/114 (18%) Query: 22 LLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLC----YDTVEKRAQSYLDA 77 L F V +L +A +E +I+ CGRHLA LC Y+ V KR+ + A Sbjct: 7 LCCFFAVYSLAAAQGGQEEFQIKVR---ICGRHLARTLADLCPNVEYEDVMKRSGARSPA 63 Query: 78 NIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLLNYC 131 + G WP +A+ A + KR G+ D+CC+ C LL+YC Sbjct: 64 LYGTVG----WP-----WARPGA----ARGKRA-GVADDCCVNSCTMDVLLSYC 103 >UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1; Aedes aegypti|Rep: Putative uncharacterized protein - Aedes aegypti (Yellowfever mosquito) Length = 161 Score = 37.1 bits (82), Expect = 0.11 Identities = 15/27 (55%), Positives = 19/27 (70%), Gaps = 1/27 (3%) Query: 106 KSKRGPGLVDECCLKPC-YTYDLLNYC 131 K + G G+V+ECC K C Y Y +LNYC Sbjct: 134 KRRPGKGIVEECCRKGCTYEYLMLNYC 160 >UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=8; Elopocephala|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Oncorhynchus keta (Chum salmon) Length = 105 Score = 37.1 bits (82), Expect = 0.11 Identities = 12/20 (60%), Positives = 16/20 (80%) Query: 112 GLVDECCLKPCYTYDLLNYC 131 G+V++CC KPC +DL NYC Sbjct: 85 GIVEQCCHKPCNIFDLQNYC 104 >UniRef50_P01308 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=85; Gnathostomata|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Homo sapiens (Human) Length = 110 Score = 36.3 bits (80), Expect = 0.19 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 51 CGRHLANARMVLCYDT-VEKRAQSYLDANIISAG--DLSSWPGLSSQYAKTRAFALAEKS 107 CG HL A ++C + ++ +A + G +L PG S + AL E S Sbjct: 31 CGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGS----LQPLAL-EGS 85 Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131 + G+V++CC C Y L NYC Sbjct: 86 LQKRGIVEQCCTSICSLYQLENYC 109 >UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4; Anopheles gambiae|Rep: Insulin-like peptide 3 precursor - Anopheles gambiae (African malaria mosquito) Length = 160 Score = 35.9 bits (79), Expect = 0.26 Identities = 14/26 (53%), Positives = 18/26 (69%), Gaps = 1/26 (3%) Query: 106 KSKRGPGLVDECCLKPCYTYDLLNYC 131 + RG G+V+ECCL+PC LL YC Sbjct: 130 RKNRG-GIVEECCLRPCGMNQLLQYC 154 >UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precursor (Insulin-related peptide) (DILP3) [Contains: Probable insulin-like peptide 3 A chain; Probable insulin-like peptide 3 B chain]; n=3; Drosophila melanogaster|Rep: Probable insulin-like peptide 3 precursor (Insulin-related peptide) (DILP3) [Contains: Probable insulin-like peptide 3 A chain; Probable insulin-like peptide 3 B chain] - Drosophila melanogaster (Fruit fly) Length = 120 Score = 35.5 bits (78), Expect = 0.34 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 51 CGRHLANARMVLC---YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKS 107 CGR L LC ++ + KR ++ N I + S L + + + + Sbjct: 34 CGRKLPETLSKLCVYGFNAMTKRTLDPVNFNQIDGFEDRS---LLERLLSDSSVQMLKTR 90 Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131 + G+ DECCLK C ++L YC Sbjct: 91 RLRDGVFDECCLKSCTMDEVLRYC 114 >UniRef50_Q8KJU8 Cluster: Putative uncharacterized protein orf280; n=1; Proteus vulgaris|Rep: Putative uncharacterized protein orf280 - Proteus vulgaris Length = 93 Score = 34.7 bits (76), Expect = 0.59 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 51 CGRHLANARMVLCYDTVEKRAQSYLDAN--IISAGDLSSWPGLSSQYAKTRAFALAE 105 C ++A A +V TV++R+ LD N + + GD S W G S Y + A E Sbjct: 28 CSAYVAEADLVKACKTVQRRSPDSLDGNKELTNEGDPSVWIGWSGDYRTPQQLAAIE 84 >UniRef50_P01315 Cluster: Insulin precursor [Contains: Insulin B chain; Insulin A chain]; n=12; Eukaryota|Rep: Insulin precursor [Contains: Insulin B chain; Insulin A chain] - Sus scrofa (Pig) Length = 108 Score = 34.7 bits (76), Expect = 0.59 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 51 CGRHLANARMVLCYDT-VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKR 109 CG HL A ++C + ++ +A AG + GL +A AL E + Sbjct: 31 CGSHLVEALYLVCGERGFFYTPKARREAENPQAGAVELGGGLGG----LQALAL-EGPPQ 85 Query: 110 GPGLVDECCLKPCYTYDLLNYC 131 G+V++CC C Y L NYC Sbjct: 86 KRGIVEQCCTSICSLYQLENYC 107 >UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep: Preproinsulin 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 107 Score = 33.9 bits (74), Expect = 1.0 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%) Query: 95 YAKTRAFALAEK-SKRGPGLVDECCLKPCYTYDLLNYC 131 Y A L EK K G+V++CC +PC Y L +YC Sbjct: 69 YEAADADPLKEKVMKMKRGIVEQCCHRPCTIYHLEDYC 106 >UniRef50_Q4AAW3 Cluster: ATP synthase A chain; n=5; Mycoplasma hyopneumoniae|Rep: ATP synthase A chain - Mycoplasma hyopneumoniae (strain J / ATCC 25934 / NCTC 10110) Length = 242 Score = 33.5 bits (73), Expect = 1.4 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 18 FKMFLLYFLIVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLD 76 F +F+L FL+++ + H K+ KI+E+P A + ++ D VE + Y++ Sbjct: 13 FTLFILVFLVIILSIIIFFHIKKAKIDESPSAVV--LFAESYLIFIDDLVETAGEGYIN 69 >UniRef50_Q31GQ6 Cluster: Beta-lactamase family protein precursor; n=1; Thiomicrospira crunogena XCL-2|Rep: Beta-lactamase family protein precursor - Thiomicrospira crunogena (strain XCL-2) Length = 412 Score = 33.1 bits (72), Expect = 1.8 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 64 YDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKT-RAFALAEKSKRGPGLV 114 YD +EKR LD S D PGL++ Y + AF KS +G ++ Sbjct: 226 YDQIEKRFLIPLDLTFTSPADRRKLPGLATGYTRADNAFGFPVKSTKGKAVM 277 >UniRef50_P68988 Cluster: Insulin [Contains: Insulin B chain; Insulin A chain]; n=14; Vertebrata|Rep: Insulin [Contains: Insulin B chain; Insulin A chain] - Lampetra fluviatilis (River lamprey) Length = 57 Score = 33.1 bits (72), Expect = 1.8 Identities = 10/20 (50%), Positives = 15/20 (75%) Query: 112 GLVDECCLKPCYTYDLLNYC 131 G+V++CC + C YD+ NYC Sbjct: 37 GIVEQCCHRKCSIYDMENYC 56 >UniRef50_A6G8V5 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 257 Score = 32.7 bits (71), Expect = 2.4 Identities = 15/47 (31%), Positives = 22/47 (46%) Query: 77 ANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCY 123 A++++A S+W LS Y A A +RG G C PC+ Sbjct: 4 ASLVAAAPPSTWAVLSLAYVGVGAVVAAHLGRRGHGFGTACAALPCW 50 >UniRef50_A6D3W3 Cluster: Ig-like repeat domain protein 1; n=1; Vibrio shilonii AK1|Rep: Ig-like repeat domain protein 1 - Vibrio shilonii AK1 Length = 1381 Score = 32.7 bits (71), Expect = 2.4 Identities = 16/54 (29%), Positives = 25/54 (46%) Query: 74 YLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDL 127 Y D + LSSW ++ A AF +A+ ++G + C L C T +L Sbjct: 524 YSDGSKRDVSTLSSWQSNNTDIATINAFGVAQGEEQGTSQISGCYLGQCATANL 577 >UniRef50_Q014P6 Cluster: [BT] KOG2132 Uncharacterized conserved protein; n=2; Ostreococcus|Rep: [BT] KOG2132 Uncharacterized conserved protein - Ostreococcus tauri Length = 275 Score = 32.7 bits (71), Expect = 2.4 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 38 DKELKIEENPRVYCGRHL-ANARMV--LCYDTVEKRAQSYLDANIIS-AGDLSSWPGLSS 93 ++ LK+E++ R + H A R+ LC D R S++D AG S LSS Sbjct: 21 EQRLKLEDDARAFARDHRGARPRLFTGLCADVPAVR--SWMDVEAFERAGAGSRTCTLSS 78 Query: 94 QYAKTRAFALAEKSKRGPGLVDECCLK 120 + A RAF A+ K G +E C K Sbjct: 79 RAADGRAFIKADCEKDESGTFEEACEK 105 >UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes aegypti|Rep: Insulin-like peptide 7 - Aedes aegypti (Yellowfever mosquito) Length = 160 Score = 32.7 bits (71), Expect = 2.4 Identities = 13/21 (61%), Positives = 15/21 (71%), Gaps = 1/21 (4%) Query: 112 GLVDECCLKPC-YTYDLLNYC 131 G+VD+CC KPC Y L NYC Sbjct: 139 GVVDDCCYKPCTLQYLLKNYC 159 >UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-like peptide 3 CG14167-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to insulin-like peptide 3 CG14167-PA - Apis mellifera Length = 73 Score = 32.3 bits (70), Expect = 3.2 Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 108 KRGPGLVDECCLKPCYTYDLLNYC 131 + G+ +ECCLK C T +L +YC Sbjct: 47 RNSKGIHEECCLKSCTTEELRSYC 70 >UniRef50_Q6VVH0 Cluster: Insulin-like peptide 2 precursor; n=4; Culicidae|Rep: Insulin-like peptide 2 precursor - Anopheles gambiae (African malaria mosquito) Length = 134 Score = 32.3 bits (70), Expect = 3.2 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 6/88 (6%) Query: 50 YCGRHLANARMVLC---YDTVEKRAQSYL--DANIISAGDLSSWPGLSSQYAKTRAFALA 104 YCGR L LC Y + Y+ AN ++++ P + Sbjct: 46 YCGRRLTETLAFLCQGRYPMLTHYRTDYVHDQANQRVKVEVATLPDTLPPGFPYPGAGVH 105 Query: 105 EKSKRGPG-LVDECCLKPCYTYDLLNYC 131 +S+R G + DECC K C +L YC Sbjct: 106 RRSRRSSGGIYDECCKKSCSYVELRAYC 133 >UniRef50_P67971 Cluster: Insulin [Contains: Insulin B chain; Insulin A chain]; n=7; Euteleostomi|Rep: Insulin [Contains: Insulin B chain; Insulin A chain] - Saimiri sciureus (Common squirrel monkey) Length = 51 Score = 32.3 bits (70), Expect = 3.2 Identities = 11/20 (55%), Positives = 13/20 (65%) Query: 112 GLVDECCLKPCYTYDLLNYC 131 G+VD+CC C Y L NYC Sbjct: 31 GVVDQCCTSICSLYQLQNYC 50 >UniRef50_A3WI78 Cluster: Sensor protein; n=1; Erythrobacter sp. NAP1|Rep: Sensor protein - Erythrobacter sp. NAP1 Length = 418 Score = 31.9 bits (69), Expect = 4.2 Identities = 11/33 (33%), Positives = 23/33 (69%) Query: 76 DANIISAGDLSSWPGLSSQYAKTRAFALAEKSK 108 +A + AGD++SWPGL ++ ++ A+ ++S+ Sbjct: 68 NAGNVIAGDIASWPGLDARVSEAGVIAIGDQSE 100 >UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia californica|Rep: Insulin-like 0 - Aplysia californica (California sea hare) Length = 262 Score = 31.9 bits (69), Expect = 4.2 Identities = 11/19 (57%), Positives = 14/19 (73%) Query: 113 LVDECCLKPCYTYDLLNYC 131 +VDECCL+PC L +YC Sbjct: 171 IVDECCLRPCNFATLQSYC 189 >UniRef50_A1HR85 Cluster: Glycosyl transferase, family 2; n=1; Thermosinus carboxydivorans Nor1|Rep: Glycosyl transferase, family 2 - Thermosinus carboxydivorans Nor1 Length = 479 Score = 31.5 bits (68), Expect = 5.5 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 3/50 (6%) Query: 1 MTLFGATKAIQEKIMPTFKMFLLYFLIVVALVSADVHDKELKIEENPRVY 50 M LFGA A+ E I+P +K Y+ + +V A HD ++ +E +Y Sbjct: 126 MLLFGAPLALSE-ILPFYKSIKEYYAGSITIVKASSHD--IEFDETDEIY 172 >UniRef50_Q5MGP2 Cluster: Hormone peptide 1 Bombyxin-related peptide; n=1; Lonomia obliqua|Rep: Hormone peptide 1 Bombyxin-related peptide - Lonomia obliqua (Moth) Length = 96 Score = 31.5 bits (68), Expect = 5.5 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 79 IISAGDLSSWPGLSSQYAKTRAFAL-----AEKSKRGPG-LVDECCLKPCYTYDLLNYC 131 I++ +L + +S+Y+KT+ + A+ + P +V+ECC+ C D L YC Sbjct: 38 IMALINLCGYEQTNSKYSKTKRSSANDDRDADADNKEPSSIVEECCINSCLLKDFLLYC 96 >UniRef50_UPI00015B5A55 Cluster: PREDICTED: similar to MGC52894 protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to MGC52894 protein - Nasonia vitripennis Length = 604 Score = 31.1 bits (67), Expect = 7.3 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 10 IQEKIMPTFKMFLLYFLIVVALVSADVHDKELKIEENPRV--YCGRHL-ANARMVLCYDT 66 +QE ++ ++LL+ L++V + DK+ E RV C + L A R V Y+ Sbjct: 431 LQEPLLVAVALYLLFLLVIVYVRLDFSIDKDEASESKLRVAGQCEKILAAQDRRVTSYNE 490 Query: 67 VEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGPG 112 ++ + +YL N LS G++ +Y K A+AE +++ G Sbjct: 491 LDDQL-NYLKTNKDVNAYLSVVKGITQEY-KNATAAIAELAQKLKG 534 >UniRef50_UPI0000660636 Cluster: projection protein PF6; n=1; Takifugu rubripes|Rep: projection protein PF6 - Takifugu rubripes Length = 1694 Score = 31.1 bits (67), Expect = 7.3 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 6/83 (7%) Query: 27 IVVALVSADVHDKELKIEENPRVYCGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLS 86 +V + +H E ++E R++ G +AN L YD +E R Q N I + Sbjct: 280 VVQLSYTVQIHSPEAELETGIRIFGG--VAN----LLYDCLEWRRQHQHYLNNIRLIKVP 333 Query: 87 SWPGLSSQYAKTRAFALAEKSKR 109 WP L Q A+ A A K+ Sbjct: 334 DWPRLPPQQAEQAAPATPRSKKK 356 >UniRef50_A5NVB0 Cluster: Sensor protein; n=5; Proteobacteria|Rep: Sensor protein - Methylobacterium sp. 4-46 Length = 1165 Score = 31.1 bits (67), Expect = 7.3 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Query: 52 GRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSWPGLSSQYAKTRAFALAEKSKRGP 111 GR LA+A VL D Y + ++ AGDL PG+ T+ F L E ++R Sbjct: 1073 GRQLADAGRVLRPDLKVLFITGYAETTVVGAGDLQ--PGME---VLTKPFVLEELARRIR 1127 Query: 112 GLV 114 G++ Sbjct: 1128 GMI 1130 >UniRef50_P13190 Cluster: Insulin [Contains: Insulin B chain; Insulin A chain]; n=3; Gnathostomata|Rep: Insulin [Contains: Insulin B chain; Insulin A chain] - Callorhynchus milii (Elephant shark) (Elephantfish) Length = 89 Score = 31.1 bits (67), Expect = 7.3 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Query: 51 CGRHLANARMVLCYDTVEKRAQSYLDANIISAGDLSSW----PGLSSQYAKTRAFALA-E 105 CG HL +A +C + R Y I G LS++ P L ++ + Sbjct: 7 CGSHLVDALYFVCGE----RGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQLA 62 Query: 106 KSKRGPGLVDECCLKPCYTYDLLNYC 131 SK G+V++CC C +L YC Sbjct: 63 GSKMKRGIVEQCCHNTCSLVNLEGYC 88 >UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-like growth factor-I; n=2; Danio rerio|Rep: PREDICTED: similar to insulin-like growth factor-I - Danio rerio Length = 188 Score = 30.7 bits (66), Expect = 9.6 Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 109 RGPGLVDECCLKPCYTYDLLNYC 131 RG G+VD+CC++ C L YC Sbjct: 81 RGKGIVDQCCVRGCDLQHLELYC 103 >UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin - Gallus gallus (Chicken) Length = 8074 Score = 30.7 bits (66), Expect = 9.6 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 40 ELKIEENPRVYCGRHLANARMVLCYDTVEKRAQ--SYLDANIISAGDLSSWPGLSSQY 95 +L+ + N R+ CG H+A+AR+ + VE+ ++ + N + S P SQ+ Sbjct: 4689 QLEDQGNYRIVCGPHIASARLTVIEPAVERHLHDTTFKEGNTCTLSCQFSIPNAKSQW 4746 >UniRef50_A0QG16 Cluster: Lipid-transfer protein; n=4; Actinomycetales|Rep: Lipid-transfer protein - Mycobacterium avium (strain 104) Length = 378 Score = 30.7 bits (66), Expect = 9.6 Identities = 12/43 (27%), Positives = 22/43 (51%) Query: 86 SSWPGLSSQYAKTRAFALAEKSKRGPGLVDECCLKPCYTYDLL 128 S W + Y++T + EK+ P +D C+ C+TY ++ Sbjct: 245 SEWDDPTEMYSRTAGPKIWEKTGLTPADMDVACMYDCFTYTVM 287 >UniRef50_P67973 Cluster: Insulin [Contains: Insulin B chain; Insulin A chain]; n=28; cellular organisms|Rep: Insulin [Contains: Insulin B chain; Insulin A chain] - Balaenoptera physalus (Finback whale) (Common rorqual) Length = 51 Score = 30.7 bits (66), Expect = 9.6 Identities = 10/20 (50%), Positives = 13/20 (65%) Query: 112 GLVDECCLKPCYTYDLLNYC 131 G+V++CC C Y L NYC Sbjct: 31 GIVEQCCTSICSLYQLENYC 50 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.324 0.137 0.418 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 134,965,028 Number of Sequences: 1657284 Number of extensions: 4695667 Number of successful extensions: 12703 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 12662 Number of HSP's gapped (non-prelim): 50 length of query: 131 length of database: 575,637,011 effective HSP length: 92 effective length of query: 39 effective length of database: 423,166,883 effective search space: 16503508437 effective search space used: 16503508437 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.6 bits) S2: 66 (30.7 bits)
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