Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000661-TA|BGIBMGA000661-PA|IPR013766|Thioredoxin domain,
IPR012336|Thioredoxin-like fold, IPR000886|Endoplasmic reticulum
targeting sequence, IPR006662|Thioredoxin-related,
IPR005788|Disulphide isomerase
(632 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D49490-1|BAA08451.1| 519|Homo sapiens protein disulfide isomera... 374 e-103
BC001625-1|AAH01625.1| 262|Homo sapiens PDIA5 protein protein. 196 2e-49
AY358646-1|AAQ89009.1| 432|Homo sapiens disulfide isomerase pro... 165 6e-40
AL133541-2|CAI19473.1| 432|Homo sapiens thioredoxin domain cont... 165 6e-40
AK075291-1|BAC11526.1| 432|Homo sapiens protein ( Homo sapiens ... 164 7e-40
AY326464-1|AAR99514.1| 363|Homo sapiens putative protein STRF8 ... 162 3e-39
AJ440721-1|CAD29430.1| 363|Homo sapiens thioredoxin related pro... 162 3e-39
BC052310-1|AAH52310.1| 360|Homo sapiens TXNDC5 protein protein. 147 9e-35
J05016-1|AAA58460.1| 645|Homo sapiens protein disulfide isomera... 141 6e-33
BC011754-1|AAH11754.1| 645|Homo sapiens protein disulfide isome... 141 6e-33
BC006344-1|AAH06344.1| 645|Homo sapiens protein disulfide isome... 141 6e-33
BC001928-1|AAH01928.1| 645|Homo sapiens protein disulfide isome... 141 6e-33
BC000425-1|AAH00425.1| 645|Homo sapiens protein disulfide isome... 141 6e-33
AC093743-1|AAQ96863.1| 645|Homo sapiens unknown protein. 141 6e-33
D49489-1|BAA08450.1| 440|Homo sapiens human P5 protein. 137 1e-31
BC001312-1|AAH01312.1| 440|Homo sapiens protein disulfide isome... 137 1e-31
AK127433-1|BAC86977.1| 492|Homo sapiens protein ( Homo sapiens ... 137 1e-31
AC092687-3|AAY24070.1| 440|Homo sapiens unknown protein. 137 1e-31
U79278-1|AAB50217.1| 421|Homo sapiens protein disulfide isomera... 136 2e-31
BC001199-1|AAH01199.1| 324|Homo sapiens TXNDC5 protein protein. 132 4e-30
AL834423-1|CAD39084.1| 244|Homo sapiens hypothetical protein pr... 113 1e-24
BC126168-1|AAI26169.1| 793|Homo sapiens DnaJ (Hsp40) homolog, s... 108 5e-23
BC117299-1|AAI17300.1| 793|Homo sapiens DnaJ (Hsp40) homolog, s... 108 5e-23
AY358577-1|AAQ88940.1| 747|Homo sapiens disulfide isomerase pro... 108 5e-23
AL832646-1|CAD89982.1| 792|Homo sapiens hypothetical protein pr... 108 5e-23
AL137648-1|CAB70858.1| 464|Homo sapiens hypothetical protein pr... 107 1e-22
AK027647-1|BAB55263.1| 793|Homo sapiens protein ( Homo sapiens ... 107 1e-22
AK027450-1|BAB55121.1| 768|Homo sapiens protein ( Homo sapiens ... 107 1e-22
AF490904-1|AAM09527.1| 747|Homo sapiens macrothioredoxin protein. 107 1e-22
AF038503-1|AAN73271.1| 793|Homo sapiens ER-resident protein ERd... 107 1e-22
AC105396-1|AAY24240.1| 464|Homo sapiens unknown protein. 107 1e-22
AK027696-1|BAB55304.1| 793|Homo sapiens protein ( Homo sapiens ... 107 2e-22
J02783-1|AAA61169.1| 508|Homo sapiens P4HB protein. 103 2e-21
M22806-1|AAC13652.1| 508|Homo sapiens prolyl 4-hydroxylase beta... 103 3e-21
BC071892-1|AAH71892.1| 508|Homo sapiens procollagen-proline, 2-... 103 3e-21
BC029617-1|AAH29617.1| 508|Homo sapiens procollagen-proline, 2-... 103 3e-21
BC010859-1|AAH10859.1| 508|Homo sapiens procollagen-proline, 2-... 103 3e-21
X05130-1|CAA28775.1| 508|Homo sapiens protein ( Human mRNA for ... 98 7e-20
Z49835-1|CAA89996.1| 505|Homo sapiens protein disulfide isomera... 89 6e-17
U75885-1|AAC51518.1| 505|Homo sapiens ER-60 protein protein. 89 6e-17
U42068-1|AAC50331.1| 505|Homo sapiens P58 protein. 89 6e-17
D16234-1|BAA03759.1| 505|Homo sapiens phospholipase C-alpha pro... 89 6e-17
BC071878-1|AAH71878.1| 505|Homo sapiens protein disulfide isome... 89 6e-17
BC036000-1|AAH36000.4| 505|Homo sapiens protein disulfide isome... 89 6e-17
BC014433-1|AAH14433.1| 505|Homo sapiens protein disulfide isome... 89 6e-17
D83485-1|BAA11928.1| 505|Homo sapiens ER-60 protease protein. 88 8e-17
AK074905-1|BAC11281.1| 277|Homo sapiens protein ( Homo sapiens ... 87 1e-16
Z69667-10|CAI95587.1| 226|Homo sapiens protein disulfide isomer... 79 6e-14
Z69667-9|CAI95586.1| 525|Homo sapiens protein disulfide isomera... 79 6e-14
U19948-1|AAC50401.1| 511|Homo sapiens protein disulfide isomera... 79 6e-14
EF450770-1|ABO43034.1| 555|Homo sapiens protein disulfide isome... 79 6e-14
BC075029-1|AAH75029.1| 519|Homo sapiens PDIA2 protein protein. 79 6e-14
BC000537-1|AAH00537.2| 520|Homo sapiens PDIA2 protein protein. 79 6e-14
AE006463-3|AAK61223.1| 525|Homo sapiens protein disulfide isome... 79 6e-14
AB127078-2|BAE48734.1| 525|Homo sapiens pancreatic protein disu... 79 6e-14
BC107422-1|AAI07423.1| 423|Homo sapiens Unknown (protein for IM... 75 1e-12
BC093794-1|AAH93794.1| 454|Homo sapiens thioredoxin domain cont... 75 1e-12
BC093792-1|AAH93792.1| 454|Homo sapiens thioredoxin domain cont... 75 1e-12
AB058733-1|BAB47459.1| 486|Homo sapiens KIAA1830 protein protein. 75 1e-12
BC032325-1|AAH32325.1| 195|Homo sapiens TXNDC10 protein protein. 71 9e-12
BC005374-1|AAH05374.1| 406|Homo sapiens thioredoxin domain cont... 68 1e-10
AL360084-2|CAH70308.1| 406|Homo sapiens thioredoxin domain cont... 68 1e-10
AL358937-2|CAI95319.1| 406|Homo sapiens thioredoxin domain cont... 68 1e-10
AL137072-1|CAH72172.1| 406|Homo sapiens thioredoxin domain cont... 68 1e-10
AJ344330-1|CAC87611.1| 406|Homo sapiens ERp44 protein protein. 68 1e-10
AB011145-1|BAA25499.1| 451|Homo sapiens KIAA0573 protein protein. 68 1e-10
AY359048-1|AAQ89407.1| 406|Homo sapiens TXNDC4 protein. 66 3e-10
BC036460-1|AAH36460.1| 280|Homo sapiens thioredoxin domain cont... 64 2e-09
BC056874-1|AAH56874.2| 280|Homo sapiens thioredoxin domain cont... 63 3e-09
AY358640-1|AAQ89003.1| 280|Homo sapiens TXNDC protein. 63 3e-09
AK075395-1|BAC11593.1| 280|Homo sapiens protein ( Homo sapiens ... 63 3e-09
AB048246-1|BAB20629.1| 280|Homo sapiens thioredoxin-related tra... 63 3e-09
Z69667-11|CAI95588.1| 154|Homo sapiens protein disulfide isomer... 60 2e-08
X07077-1|CAA30112.1| 216|Homo sapiens glutathione-insulin trans... 60 2e-08
BC014504-1|AAH14504.1| 185|Homo sapiens P4HB protein protein. 60 2e-08
U97276-1|AAC09010.2| 747|Homo sapiens quiescin protein. 54 2e-06
BC100023-1|AAI00024.1| 747|Homo sapiens quiescin Q6 protein. 54 2e-06
BC017692-1|AAH17692.1| 604|Homo sapiens quiescin Q6 protein. 54 2e-06
AY358941-1|AAQ89300.1| 747|Homo sapiens QSCN6 protein. 54 2e-06
AL390718-7|CAI14839.1| 604|Homo sapiens quiescin Q6 protein. 54 2e-06
AL390718-6|CAI14838.1| 747|Homo sapiens quiescin Q6 protein. 54 2e-06
AJ318051-1|CAC85331.1| 698|Homo sapiens putative sulfhydryl oxi... 54 2e-06
AF361868-1|AAM00263.1| 604|Homo sapiens sulfhydryl oxidase prot... 54 2e-06
AB209280-1|BAD92517.1| 753|Homo sapiens quiescin Q6 isoform a v... 54 2e-06
CR392000-1|CAM28352.1| 698|Homo sapiens quiescin Q6-like 1 prot... 53 3e-06
AL138781-1|CAI16881.2| 698|Homo sapiens quiescin Q6-like 1 prot... 53 3e-06
U78678-1|AAB41631.1| 166|Homo sapiens thioredoxin protein. 52 5e-06
CR541917-1|CAG46715.1| 166|Homo sapiens TXN2 protein. 52 5e-06
CR541896-1|CAG46694.1| 166|Homo sapiens TXN2 protein. 52 5e-06
CR456601-1|CAG30487.1| 166|Homo sapiens TXN2 protein. 52 5e-06
BC050610-1|AAH50610.1| 166|Homo sapiens thioredoxin 2 protein. 52 5e-06
BC013726-1|AAH13726.1| 166|Homo sapiens thioredoxin 2 protein. 52 5e-06
AL022313-1|CAI19226.1| 197|Homo sapiens thioredoxin 2 protein. 52 5e-06
AF480262-1|AAN05576.1| 166|Homo sapiens mitochondrial thioredox... 52 5e-06
AF276920-1|AAF86467.1| 166|Homo sapiens thioredoxin 2 protein. 52 5e-06
X77584-1|CAA54687.1| 105|Homo sapiens ATL-derived factor/thiore... 52 8e-06
X54539-1|CAA38410.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
CR407665-1|CAG28593.1| 105|Homo sapiens TXN protein. 52 8e-06
BC054866-1|AAH54866.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
BC003377-1|AAH03377.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
AY004872-1|AAF87085.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
AL158158-1|CAI14066.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
AF548001-1|AAN33187.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
AF313911-1|AAG34699.1| 105|Homo sapiens thioredoxin protein. 52 8e-06
J04026-1|AAA74596.1| 105|Homo sapiens thioredoxin protein. 49 4e-05
AF276919-1|AAF86466.1| 105|Homo sapiens thioredoxin 1 protein. 49 4e-05
L42379-1|AAA89173.1| 793|Homo sapiens bone-derived growth facto... 49 6e-05
BC107425-1|AAI07426.1| 332|Homo sapiens DNAJC10 protein protein. 48 1e-04
AY089971-1|AAM09954.1| 275|Homo sapiens macrothioredoxin isofor... 48 1e-04
AY010234-1|AAG32626.1| 332|Homo sapiens endoplasmic reticulum D... 48 1e-04
AC073951-1|AAX88931.1| 329|Homo sapiens unknown protein. 48 1e-04
BC130551-1|AAI30552.1| 115|Homo sapiens thioredoxin domain cont... 44 0.002
BC130549-1|AAI30550.1| 115|Homo sapiens thioredoxin domain cont... 44 0.002
AF305830-1|AAQ14501.1| 115|Homo sapiens thioredoxin 6 protein. 44 0.002
BC044936-1|AAH44936.1| 584|Homo sapiens protein disulfide isome... 44 0.002
BC042607-1|AAH42607.1| 584|Homo sapiens protein disulfide isome... 44 0.002
AK097476-1|BAC05068.1| 584|Homo sapiens protein ( Homo sapiens ... 44 0.002
CR457152-1|CAG33433.1| 330|Homo sapiens LOC51061 protein. 43 0.003
BC050132-1|AAH50132.1| 486|Homo sapiens thioredoxin domain cont... 43 0.003
BC033787-1|AAH33787.1| 349|Homo sapiens thioredoxin domain cont... 43 0.003
BC013727-1|AAH13727.1| 330|Homo sapiens TXNDC11 protein protein. 43 0.003
BC002856-1|AAH02856.1| 985|Homo sapiens TXNDC11 protein protein. 43 0.003
AY359004-1|AAQ89363.1| 349|Homo sapiens DJ971N18.2 protein. 43 0.003
AL021396-2|CAC17521.1| 349|Homo sapiens thioredoxin domain cont... 43 0.003
AK075404-1|BAC11599.1| 349|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK074838-1|BAC11237.1| 349|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK027646-1|BAB55262.1| 958|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK027464-1|BAB55129.1| 506|Homo sapiens protein ( Homo sapiens ... 43 0.003
AF131780-1|AAD20043.1| 330|Homo sapiens Unknown protein. 43 0.003
AF080095-1|AAK94950.1| 486|Homo sapiens sperm-specific thioredo... 43 0.003
AB037765-1|BAA92582.2| 858|Homo sapiens KIAA1344 protein protein. 43 0.004
AK097656-1|BAC05133.1| 553|Homo sapiens protein ( Homo sapiens ... 42 0.007
BC018635-1|AAH18635.1| 278|Homo sapiens TXNDC11 protein protein. 42 0.009
AL158158-4|CAI14069.1| 101|Homo sapiens thioredoxin domain cont... 42 0.009
BC005289-1|AAH05289.1| 335|Homo sapiens thioredoxin-like 2 prot... 41 0.015
AL139123-3|CAC40691.1| 335|Homo sapiens thioredoxin-like 3 prot... 41 0.015
AJ010841-1|CAA09375.1| 335|Homo sapiens thioredoxin-like protei... 41 0.015
AF118652-1|AAF28844.1| 335|Homo sapiens PKCq-interacting protei... 41 0.015
AF118649-1|AAF28841.1| 335|Homo sapiens PKCq-interacting protei... 41 0.015
BX538131-1|CAD98032.1| 355|Homo sapiens hypothetical protein pr... 36 0.33
BC032568-1|AAH32568.1| 360|Homo sapiens chromosome 5 open readi... 36 0.33
BC008953-1|AAH08953.1| 172|Homo sapiens thioredoxin domain cont... 36 0.33
BC008913-1|AAH08913.1| 172|Homo sapiens thioredoxin domain cont... 36 0.33
BC001615-1|AAH01615.1| 360|Homo sapiens chromosome 5 open readi... 36 0.33
BC001493-1|AAH01493.1| 172|Homo sapiens thioredoxin domain cont... 36 0.33
AY358982-1|AAQ89341.1| 172|Homo sapiens ETRP713 protein. 36 0.33
AY358649-1|AAQ89012.1| 360|Homo sapiens disulfide isomerase pro... 36 0.33
AL445685-5|CAI17031.1| 172|Homo sapiens thioredoxin domain cont... 36 0.33
AK056512-1|BAB71199.1| 360|Homo sapiens protein ( Homo sapiens ... 36 0.33
AK026278-1|BAB15427.1| 343|Homo sapiens protein ( Homo sapiens ... 36 0.33
AF543416-1|AAN34781.1| 172|Homo sapiens thioredoxin-like protei... 36 0.33
AF131758-1|AAD20035.1| 172|Homo sapiens Unknown protein. 36 0.33
AF314529-1|AAQ14565.1| 177|Homo sapiens endoplasmic reticulum D... 35 1.0
AF196568-1|AAG28497.1| 330|Homo sapiens thioredoxin-like 2 prot... 34 1.3
BC034713-1|AAH34713.1| 78|Homo sapiens DNAJC10 protein protein. 34 1.8
AL158158-2|CAI14067.1| 85|Homo sapiens thioredoxin protein. 34 1.8
AF065241-1|AAC17430.1| 84|Homo sapiens thioredoxin delta 3 pro... 34 1.8
BC107054-1|AAI07055.1| 174|Homo sapiens TXNDC6 protein protein. 32 5.4
BC036816-1|AAH36816.1| 588|Homo sapiens thioredoxin domain cont... 32 5.4
AK094830-1|BAC04430.1| 263|Homo sapiens protein ( Homo sapiens ... 32 5.4
AF305596-1|AAN04258.1| 588|Homo sapiens sperm-specific thioredo... 32 5.4
AF202051-1|AAF20909.2| 588|Homo sapiens NM23-H8 protein. 32 5.4
DQ120656-1|ABB92441.1| 368|Homo sapiens rcADH5 protein. 32 7.1
BC047604-1|AAH47604.2| 671|Homo sapiens QSCN6L1 protein protein. 32 7.1
BC023532-1|AAH23532.1| 641|Homo sapiens WW domain binding prote... 32 7.1
BC001621-1|AAH01621.1| 641|Homo sapiens WW domain binding prote... 32 7.1
AF118023-1|AAD30425.1| 641|Homo sapiens SH3 domain-binding prot... 32 7.1
AB029309-1|BAA88410.1| 641|Homo sapiens Npw38-binding protein N... 32 7.1
BC093062-1|AAH93062.1| 258|Homo sapiens TXNDC14 protein protein. 31 9.4
BC000666-1|AAH00666.1| 296|Homo sapiens thioredoxin domain cont... 31 9.4
AY358501-1|AAQ88865.1| 296|Homo sapiens AVLA237 protein. 31 9.4
AK223058-1|BAD96778.1| 296|Homo sapiens thioredoxin-related tra... 31 9.4
AK075359-1|BAC11569.1| 372|Homo sapiens protein ( Homo sapiens ... 31 9.4
AF132965-1|AAD27740.1| 296|Homo sapiens CGI-31 protein protein. 31 9.4
AF059753-1|AAG43122.1| 372|Homo sapiens My009 protein protein. 31 9.4
>D49490-1|BAA08451.1| 519|Homo sapiens protein disulfide
isomerase-related protein (PDIR) protein.
Length = 519
Score = 374 bits (920), Expect = e-103
Identities = 202/503 (40%), Positives = 293/503 (58%), Gaps = 20/503 (3%)
Query: 1 MTISLVLSSVETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKET 60
+ I +VL S + + ++++ ISD KD KK+LRT+ NVLVL+ A N + +
Sbjct: 11 LAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTV 70
Query: 61 ADTMRGQATLILIDCNNSDNKKLCKKLKV--SP-EKPFILKHYKDGDFNKDYDRSESVSS 117
A ++GQ T+ +DC +++++KLCKK+KV SP +K L HY+DG F+ +Y+R+ + S
Sbjct: 71 AQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKS 130
Query: 118 MCNFLRDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKS 177
+ FL+DP G WEEDP A D+ HL + + LKK K +IMFYAPWC CK
Sbjct: 131 IVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLLKK---EEKPLLIMFYAPWCSMCKR 187
Query: 178 MKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFERGQFRFPY-NGEN 236
M P + +AA L+G ++LA ++V I++ Y++ GFPT+ YFE+G+F F Y N +
Sbjct: 188 MMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGS 247
Query: 237 KRQAIVEFMRDPVAQPKQKKKDVVDESWARD-TDVVHLNGDSFDAILAKAEHALVVFYAP 295
+ IVE++++P QP Q + V + WA + V HL + FD + + LV+F+AP
Sbjct: 248 TAEDIVEWLKNP--QPPQPQ--VPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAP 303
Query: 296 WCGHCKRIKPEFEKAATKIKTE-KINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEF 354
WCGHCK++KPEFEKAA + E +G+LAAVDAT LA RF + +PTLKYF GE
Sbjct: 304 WCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGE- 362
Query: 355 KFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIV 414
K+ R + + + ++++ V HL FR TL+K KH++V
Sbjct: 363 KYAVPVLRTKKKFLEWMQN---PEAPPPPEPTWEEQQTSVLHLVGDNFRETLKKKKHTLV 419
Query: 415 MFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT--LHQDLCANYNVKGYPTIKYF 472
MFYAPWC HCK P F A+ F D+ +A AVDC +QDLC VKGYPT Y+
Sbjct: 420 MFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYPTFHYY 479
Query: 473 SYFDKAVKDYTGGQKEGDFVSFI 495
Y K + Y + E F ++I
Sbjct: 480 HY-GKFAEKYDSDRTELGFTNYI 501
Score = 190 bits (462), Expect = 2e-47
Identities = 126/437 (28%), Positives = 207/437 (47%), Gaps = 28/437 (6%)
Query: 189 LKGESILAAIDVAKPGNSKIRQLYNITGFPT-----LLYFERGQFRFPYNGENKRQAIVE 243
+KG+ + +D + K+ + + P L +++ G F YN ++IV
Sbjct: 74 VKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVA 133
Query: 244 FMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDS-FDAILAKAEHALVV-FYAPWCGHCK 301
F++DP P + ++ A+D VVHL+ + F +L K E L++ FYAPWC CK
Sbjct: 134 FLKDPKGPPLWE-----EDPGAKD--VVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCK 186
Query: 302 RIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDA-GH 360
R+ P F+KAAT+++ + + + E ++ + V+G+PT+ YF KG F F +
Sbjct: 187 RMMPHFQKAATQLRGHAVLAGMNVYSSEFE-NIKEEYSVRGFPTICYFEKGRFLFQYDNY 245
Query: 361 ARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPW 420
+ I+ ++K+ V HL F +++ +VMF+APW
Sbjct: 246 GSTAEDIVEWLKNPQPPQPQVPETPWADEGGS-VYHLTDEDFDQFVKEHSSVLVMFHAPW 304
Query: 421 CGHCKSTKPEFVKAAEQFADELMVA--FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKA 478
CGHCK KPEF KAAE E + AVD T+++ L +++ +PT+KYF +K
Sbjct: 305 CGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKY 364
Query: 479 VKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVLLAFDDDFEKIISVPTP 538
+K+ F+ ++ N + P+ T + +VL D+F + +
Sbjct: 365 AVPVLRTKKK--FLEWMQNP-----EAPPPPEPTWEEQ-QTSVLHLVGDNFRETLKKKKH 416
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTE-NVPVKAVALEAAENPKAADFAGIQTLPTF 597
T+VMFYA WC HC P F+ A A K + + AV +N ++ PTF
Sbjct: 417 TLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYPTF 476
Query: 598 KLFAAGKYVTDYDGDRS 614
+ GK+ YD DR+
Sbjct: 477 HYYHYGKFAEKYDSDRT 493
Score = 84.6 bits (200), Expect = 9e-16
Identities = 64/228 (28%), Positives = 113/228 (49%), Gaps = 17/228 (7%)
Query: 27 KDFKKILRTKTNVLVLF-VNEMKKAHNMVEVFKETADTMRGQATL--ILIDCNNSDNKKL 83
+DF + ++ ++VLV+F M F++ A+ + G+A +L + + NK L
Sbjct: 284 EDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKAL 343
Query: 84 CKKLKVSPEKPFILKHYKDGD-FNKDYDRSES--VSSMCNFLRDPTGDLPWEEDPTAVDI 140
++ +S E P LK++K+G+ + R++ + M N P + WEE T+V
Sbjct: 344 AERFHIS-EFP-TLKYFKNGEKYAVPVLRTKKKFLEWMQNPEAPPPPEPTWEEQQTSV-- 399
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILA--AI 198
HL+ G+ + LKK K +++MFYAPWC +CK + P + A K + +A A+
Sbjct: 400 LHLV-GDNFRETLKK----KKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAV 454
Query: 199 DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMR 246
D K N + Q + G+PT Y+ G+F Y+ + ++R
Sbjct: 455 DCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYIR 502
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 509 PKTTQDAGFGANVLLAFDDDFEKIISVPT-PTIVMFYATWCSHCVTAKPAFSRLATALKT 567
P +D G V L + DF +++ P ++MFYA WCS C P F + AT L+
Sbjct: 142 PLWEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRG 201
Query: 568 ENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRST-EDLLKFCK 623
V + + + ++E + ++ PT F G+++ YD ST ED++++ K
Sbjct: 202 HAV-LAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLK 257
>BC001625-1|AAH01625.1| 262|Homo sapiens PDIA5 protein protein.
Length = 262
Score = 196 bits (478), Expect = 2e-49
Identities = 100/250 (40%), Positives = 155/250 (62%), Gaps = 7/250 (2%)
Query: 1 MTISLVLSSVETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKET 60
+ I +VL S + + ++++ ISD KD KK+LRT+ NVLVL+ A N + +
Sbjct: 11 LAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTV 70
Query: 61 ADTMRGQATLILIDCNNSDNKKLCKKLKV--SP-EKPFILKHYKDGDFNKDYDRSESVSS 117
A ++GQ T+ +DC +++++KLCKK+KV SP +K L HY+DG F+ +Y+R+ + S
Sbjct: 71 AQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKS 130
Query: 118 MCNFLRDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKS 177
+ FL+DP G WEEDP A D+ HL + + LKK K +IMFYAPWC CK
Sbjct: 131 IVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLLKK---EEKPLLIMFYAPWCSMCKR 187
Query: 178 MKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFERGQFRFPY-NGEN 236
M P + +AA L+G ++LA ++V I++ Y++ GFPT+ YFE+G+F F Y N +
Sbjct: 188 MMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGS 247
Query: 237 KRQAIVEFMR 246
+ IVE+++
Sbjct: 248 TAEDIVEWLK 257
Score = 88.2 bits (209), Expect = 8e-17
Identities = 56/194 (28%), Positives = 103/194 (53%), Gaps = 20/194 (10%)
Query: 189 LKGESILAAIDVAKPGNSKIRQLYNITGFPT-----LLYFERGQFRFPYNGENKRQAIVE 243
+KG+ + +D + K+ + + P L +++ G F YN ++IV
Sbjct: 74 VKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVA 133
Query: 244 FMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDS-FDAILAKAEHALVV-FYAPWCGHCK 301
F++DP P + ++ A+D VVHL+ + F +L K E L++ FYAPWC CK
Sbjct: 134 FLKDPKGPPLWE-----EDPGAKD--VVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCK 186
Query: 302 RIKPEFEKAATKIKTEKINGILAAVD--ATKEPDLASRFGVKGYPTLKYFNKGEFKFD-A 358
R+ P F+KAAT+++ + +LA ++ +++ ++ + V+G+PT+ YF KG F F
Sbjct: 187 RMMPHFQKAATQLRG---HAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYD 243
Query: 359 GHARQEDQIISFIK 372
+ + I+ ++K
Sbjct: 244 NYGSTAEDIVEWLK 257
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/81 (43%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 394 VRHLDSST-FRNTLRKI-KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
V HLDS FR L+K K ++MFYAPWC CK P F KAA Q ++A V
Sbjct: 153 VVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYS 212
Query: 452 TLHQDLCANYNVKGYPTIKYF 472
+ +++ Y+V+G+PTI YF
Sbjct: 213 SEFENIKEEYSVRGFPTICYF 233
Score = 57.2 bits (132), Expect = 2e-07
Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Query: 509 PKTTQDAGFGANVLLAFDDDFEKIISVPT-PTIVMFYATWCSHCVTAKPAFSRLATALKT 567
P +D G V L + DF +++ P ++MFYA WCS C P F + AT L+
Sbjct: 142 PLWEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRG 201
Query: 568 ENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRST-EDLLKFCKR 624
V + + + ++E + ++ PT F G+++ YD ST ED++++ K+
Sbjct: 202 HAV-LAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKK 258
>AY358646-1|AAQ89009.1| 432|Homo sapiens disulfide isomerase
protein.
Length = 432
Score = 165 bits (400), Expect = 6e-40
Identities = 110/381 (28%), Positives = 169/381 (44%), Gaps = 20/381 (5%)
Query: 266 RDTDVVHL-NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKT-EKINGIL 323
+D HL D F + A H V+F+APWCGHC+R++P + K + E +
Sbjct: 58 QDPHSKHLYTADMFTHGIQSAAH-FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYV 116
Query: 324 AAVDATKEPDLASRFGVKGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXXX 379
A VD T D+ S GV+GYPTLK F G+ K+ Q E+ ++ + +
Sbjct: 117 AKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPE 176
Query: 380 XXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFA 439
+ L +S F + + H + F+APWCGHCK+ P + + A
Sbjct: 177 PEVEPPSAPELKQGLYELSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLE 235
Query: 440 DELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQM 499
V G VDCT H +LC+ V+GYPT+ +F K V Y G + ++ +Q+
Sbjct: 236 HSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQL 294
Query: 500 GTKQTSQKAPKTTQDAGFGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHC 551
+T T +A A VL +++F+ I+ T + FYA WC HC
Sbjct: 295 QRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHC 353
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDG 611
T P + L+ VK ++ ++ PT LF GK V+++ G
Sbjct: 354 KTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSG 413
Query: 612 DRSTEDLLKFCKRHAEVKDEL 632
R + L +F ++ KDEL
Sbjct: 414 GRDLDSLHRFVL--SQAKDEL 432
Score = 150 bits (364), Expect = 1e-35
Identities = 96/353 (27%), Positives = 172/353 (48%), Gaps = 26/353 (7%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLL 221
+MF+APWCG+C+ ++P + + GD A + VAK +S + + G+PTL
Sbjct: 82 VMFFAPWCGHCQRLQPTWND-LGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140
Query: 222 YFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFD 279
F+ GQ Y G Q + +M + + + V+ A + + L+ +F+
Sbjct: 141 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 200
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRF 338
+A+ +H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S
Sbjct: 201 LHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGN 257
Query: 339 GVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX---------- 387
V+GYPTL +F G+ K D +++ + + +++
Sbjct: 258 QVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAE 316
Query: 388 -XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVA 445
V L + F +T+ + + + FYAPWCGHCK+ P + + + ++F V
Sbjct: 317 PEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVK 375
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
VDCT +++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 376 IAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 427
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 139 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 198
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 199 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 255
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWA----- 265
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 256 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 315
Query: 266 -RDTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 316 EPEADKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 373
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 374 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 424
>AL133541-2|CAI19473.1| 432|Homo sapiens thioredoxin domain
containing 5 protein.
Length = 432
Score = 165 bits (400), Expect = 6e-40
Identities = 110/381 (28%), Positives = 169/381 (44%), Gaps = 20/381 (5%)
Query: 266 RDTDVVHL-NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKT-EKINGIL 323
+D HL D F + A H V+F+APWCGHC+R++P + K + E +
Sbjct: 58 QDPHSKHLYTADMFTHGIQSAAH-FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYV 116
Query: 324 AAVDATKEPDLASRFGVKGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXXX 379
A VD T D+ S GV+GYPTLK F G+ K+ Q E+ ++ + +
Sbjct: 117 AKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPE 176
Query: 380 XXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFA 439
+ L +S F + + H + F+APWCGHCK+ P + + A
Sbjct: 177 PEVEPPSAPELKQGLYELSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLE 235
Query: 440 DELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQM 499
V G VDCT H +LC+ V+GYPT+ +F K V Y G + ++ +Q+
Sbjct: 236 HSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQL 294
Query: 500 GTKQTSQKAPKTTQDAGFGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHC 551
+T T +A A VL +++F+ I+ T + FYA WC HC
Sbjct: 295 QRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHC 353
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDG 611
T P + L+ VK ++ ++ PT LF GK V+++ G
Sbjct: 354 KTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSG 413
Query: 612 DRSTEDLLKFCKRHAEVKDEL 632
R + L +F ++ KDEL
Sbjct: 414 GRDLDSLHRFVL--SQAKDEL 432
Score = 150 bits (364), Expect = 1e-35
Identities = 96/353 (27%), Positives = 172/353 (48%), Gaps = 26/353 (7%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLL 221
+MF+APWCG+C+ ++P + + GD A + VAK +S + + G+PTL
Sbjct: 82 VMFFAPWCGHCQRLQPTWND-LGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140
Query: 222 YFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFD 279
F+ GQ Y G Q + +M + + + V+ A + + L+ +F+
Sbjct: 141 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 200
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRF 338
+A+ +H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S
Sbjct: 201 LHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGN 257
Query: 339 GVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX---------- 387
V+GYPTL +F G+ K D +++ + + +++
Sbjct: 258 QVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAE 316
Query: 388 -XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVA 445
V L + F +T+ + + + FYAPWCGHCK+ P + + + ++F V
Sbjct: 317 PEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVK 375
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
VDCT +++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 376 IAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 427
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 139 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 198
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 199 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 255
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWA----- 265
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 256 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 315
Query: 266 -RDTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 316 EPEADKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 373
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 374 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 424
>AK075291-1|BAC11526.1| 432|Homo sapiens protein ( Homo sapiens
cDNA FLJ90810 fis, clone Y79AA1000876, weakly similar to
PROTEIN DISULFIDE ISOMERASE-RELATED PROTEIN PRECURSOR.
).
Length = 432
Score = 164 bits (399), Expect = 7e-40
Identities = 110/381 (28%), Positives = 169/381 (44%), Gaps = 20/381 (5%)
Query: 266 RDTDVVHL-NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKT-EKINGIL 323
+D HL D F + A H V+F+APWCGHC+R++P + K + E +
Sbjct: 58 QDPHSKHLYTADMFTHGIQSAAH-FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYV 116
Query: 324 AAVDATKEPDLASRFGVKGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXXX 379
A VD T D+ S GV+GYPTLK F G+ K+ Q E+ ++ + +
Sbjct: 117 AKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPE 176
Query: 380 XXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFA 439
+ L +S F + + H + F+APWCGHCK+ P + + A
Sbjct: 177 PEVEPPSAPELKQGLYELSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLE 235
Query: 440 DELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQM 499
V G VDCT H +LC+ V+GYPT+ +F K V Y G + ++ +Q+
Sbjct: 236 HSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQL 294
Query: 500 GTKQTSQKAPKTTQDAGFGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHC 551
+T T +A A VL +++F+ I+ T + FYA WC HC
Sbjct: 295 QRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHC 353
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDG 611
T P + L+ VK ++ ++ PT LF GK V+++ G
Sbjct: 354 RTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSG 413
Query: 612 DRSTEDLLKFCKRHAEVKDEL 632
R + L +F ++ KDEL
Sbjct: 414 GRDLDSLHRFVL--SQAKDEL 432
Score = 149 bits (361), Expect = 3e-35
Identities = 95/353 (26%), Positives = 172/353 (48%), Gaps = 26/353 (7%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLL 221
+MF+APWCG+C+ ++P + + GD A + VAK +S + + G+PTL
Sbjct: 82 VMFFAPWCGHCQRLQPTWND-LGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140
Query: 222 YFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFD 279
F+ GQ Y G Q + +M + + + V+ A + + L+ +F+
Sbjct: 141 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 200
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRF 338
+A+ +H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S
Sbjct: 201 LHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGN 257
Query: 339 GVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX---------- 387
V+GYPTL +F G+ K D +++ + + +++
Sbjct: 258 QVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAE 316
Query: 388 -XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVA 445
V L + F +T+ + + + FYAPWCGHC++ P + + + ++F V
Sbjct: 317 PEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCRTLAPTWEELSKKEFPGLAGVK 375
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
VDCT +++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 376 IAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 427
Score = 107 bits (258), Expect = 9e-23
Identities = 78/291 (26%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 139 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 198
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 199 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 255
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWA----- 265
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 256 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 315
Query: 266 -RDTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHC+ + P +E+ + K + + G
Sbjct: 316 EPEADKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCRTLAPTWEELSKK-EFPGLAG 373
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 374 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 424
>AY326464-1|AAR99514.1| 363|Homo sapiens putative protein STRF8
protein.
Length = 363
Score = 162 bits (394), Expect = 3e-39
Identities = 105/364 (28%), Positives = 163/364 (44%), Gaps = 19/364 (5%)
Query: 282 LAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKT-EKINGILAAVDATKEPDLASRFGV 340
+ A H V+F+APWCGHC+R++P + K + E +A VD T D+ S GV
Sbjct: 6 IQSAAH-FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGV 64
Query: 341 KGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRH 396
+GYPTLK F G+ K+ Q E+ ++ + + +
Sbjct: 65 RGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYE 124
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQD 456
L +S F + + H + F+APWCGHCK+ P + + A V G VDCT H +
Sbjct: 125 LSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYE 183
Query: 457 LCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAG 516
LC+ V+GYPT+ +F K V Y G + ++ +Q+ +T T +A
Sbjct: 184 LCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAP 242
Query: 517 FGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTE 568
A VL +++F+ I+ T + FYA WC HC T P + L+
Sbjct: 243 VLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKKEFPG 301
Query: 569 NVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHAEV 628
VK ++ ++ PT LF GK V+++ G R + L +F ++
Sbjct: 302 LAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVL--SQA 359
Query: 629 KDEL 632
KDEL
Sbjct: 360 KDEL 363
Score = 150 bits (364), Expect = 1e-35
Identities = 96/353 (27%), Positives = 172/353 (48%), Gaps = 26/353 (7%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLL 221
+MF+APWCG+C+ ++P + + GD A + VAK +S + + G+PTL
Sbjct: 13 VMFFAPWCGHCQRLQPTWND-LGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 71
Query: 222 YFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFD 279
F+ GQ Y G Q + +M + + + V+ A + + L+ +F+
Sbjct: 72 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 131
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRF 338
+A+ +H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S
Sbjct: 132 LHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGN 188
Query: 339 GVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX---------- 387
V+GYPTL +F G+ K D +++ + + +++
Sbjct: 189 QVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAE 247
Query: 388 -XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVA 445
V L + F +T+ + + + FYAPWCGHCK+ P + + + ++F V
Sbjct: 248 PEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVK 306
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
VDCT +++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 307 IAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 358
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 70 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 129
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 130 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 186
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWA----- 265
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 187 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 246
Query: 266 -RDTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 247 EPEADKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 304
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 305 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 355
>AJ440721-1|CAD29430.1| 363|Homo sapiens thioredoxin related
protein protein.
Length = 363
Score = 162 bits (394), Expect = 3e-39
Identities = 105/364 (28%), Positives = 163/364 (44%), Gaps = 19/364 (5%)
Query: 282 LAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKT-EKINGILAAVDATKEPDLASRFGV 340
+ A H V+F+APWCGHC+R++P + K + E +A VD T D+ S GV
Sbjct: 6 IQSAAH-FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGV 64
Query: 341 KGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRH 396
+GYPTLK F G+ K+ Q E+ ++ + + +
Sbjct: 65 RGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYE 124
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQD 456
L +S F + + H + F+APWCGHCK+ P + + A V G VDCT H +
Sbjct: 125 LSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYE 183
Query: 457 LCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAG 516
LC+ V+GYPT+ +F K V Y G + ++ +Q+ +T T +A
Sbjct: 184 LCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAP 242
Query: 517 FGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTE 568
A VL +++F+ I+ T + FYA WC HC T P + L+
Sbjct: 243 VLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKKEFPG 301
Query: 569 NVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHAEV 628
VK ++ ++ PT LF GK V+++ G R + L +F ++
Sbjct: 302 LAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVL--SQA 359
Query: 629 KDEL 632
KDEL
Sbjct: 360 KDEL 363
Score = 150 bits (364), Expect = 1e-35
Identities = 96/353 (27%), Positives = 172/353 (48%), Gaps = 26/353 (7%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLL 221
+MF+APWCG+C+ ++P + + GD A + VAK +S + + G+PTL
Sbjct: 13 VMFFAPWCGHCQRLQPTWND-LGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 71
Query: 222 YFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFD 279
F+ GQ Y G Q + +M + + + V+ A + + L+ +F+
Sbjct: 72 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 131
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRF 338
+A+ +H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S
Sbjct: 132 LHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGN 188
Query: 339 GVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX---------- 387
V+GYPTL +F G+ K D +++ + + +++
Sbjct: 189 QVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAE 247
Query: 388 -XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVA 445
V L + F +T+ + + + FYAPWCGHCK+ P + + + ++F V
Sbjct: 248 PEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVK 306
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
VDCT +++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 307 IAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 358
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 70 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 129
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 130 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 186
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWA----- 265
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 187 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 246
Query: 266 -RDTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 247 EPEADKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 304
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 305 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 355
>BC052310-1|AAH52310.1| 360|Homo sapiens TXNDC5 protein protein.
Length = 360
Score = 147 bits (357), Expect = 9e-35
Identities = 98/349 (28%), Positives = 153/349 (43%), Gaps = 18/349 (5%)
Query: 297 CGHCKRIKPEFEKAATKIKT-EKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGE-- 353
CGHC+R++P + K + E +A VD T D+ S GV+GYPTLK F G+
Sbjct: 17 CGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEA 76
Query: 354 FKFDAGHARQ--EDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKH 411
K+ Q E+ ++ + + + L +S F + + H
Sbjct: 77 VKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDH 136
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+ F+APWCGHCK+ P + + A V G VDCT H +LC+ V+GYPT+ +
Sbjct: 137 -FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLW 195
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGA--------NVLL 523
F K V Y G + ++ +Q+ +T T +A A VL
Sbjct: 196 FR-DGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLA 254
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
+++F+ I+ T + FYA WC HC T P + L+ VK ++
Sbjct: 255 LTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAER 313
Query: 584 KAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHAEVKDEL 632
++ PT LF GK V+++ G R + L +F ++ KDEL
Sbjct: 314 NICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVL--SQAKDEL 360
Score = 134 bits (325), Expect = 7e-31
Identities = 91/346 (26%), Positives = 165/346 (47%), Gaps = 26/346 (7%)
Query: 172 CGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTLLYFERGQF 228
CG+C+ ++P + + GD A + VAK +S + + G+PTL F+ GQ
Sbjct: 17 CGHCQRLQPTWNDL-GDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQE 75
Query: 229 RFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARD--TDVVHLNGDSFDAILAKAE 286
Y G Q + +M + + + V+ A + + L+ +F+ +A+ +
Sbjct: 76 AVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGD 135
Query: 287 HALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKINGILAAVDATKEPDLASRFGVKGYPT 345
H + F+APWCGHCK + P +E+ A ++ +E + + VD T+ +L S V+GYPT
Sbjct: 136 H-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK--IGKVDCTQHYELCSGNQVRGYPT 192
Query: 346 LKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXXXXXXXXX-----------XXXXXX 393
L +F G+ K D +++ + + +++
Sbjct: 193 LLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGT 251
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVAFGAVDCT 452
V L + F +T+ + + + FYAPWCGHCK+ P + + + ++F V VDCT
Sbjct: 252 VLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCT 310
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
+++C+ Y+V+GYPT+ F K V +++GG+ F+ +Q
Sbjct: 311 AERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDLDSLHRFVLSQ 355
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 67 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 126
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 127 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 183
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWAR---- 266
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 184 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 243
Query: 267 --DTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 244 EPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 301
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 302 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 352
>J05016-1|AAA58460.1| 645|Homo sapiens protein disulfide
isomerase-related protein protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>BC011754-1|AAH11754.1| 645|Homo sapiens protein disulfide
isomerase family A, member 4 protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>BC006344-1|AAH06344.1| 645|Homo sapiens protein disulfide
isomerase family A, member 4 protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>BC001928-1|AAH01928.1| 645|Homo sapiens protein disulfide
isomerase family A, member 4 protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>BC000425-1|AAH00425.1| 645|Homo sapiens protein disulfide
isomerase family A, member 4 protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>AC093743-1|AAQ96863.1| 645|Homo sapiens unknown protein.
Length = 645
Score = 141 bits (342), Expect = 6e-33
Identities = 84/271 (30%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 231 PYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALV 290
P + R+ +E + + +++D D + V+ LN +FD +A + L+
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEED--DLEVKEENGVLVLNDANFDNFVADKDTVLL 84
Query: 291 VFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFN 350
FYAPWCGHCK+ PE+EK A +K + +A +DAT LASRF V GYPT+K
Sbjct: 85 EFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
Query: 351 KGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIK 410
KG+ D +R +++I++ +++ L F +
Sbjct: 145 KGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLV--------LTKENFDEVVNDAD 195
Query: 411 HSIVMFYAPWCGHCKSTKPEFVKAAEQFADEL-MVAFGAVDCTLHQDLCANYNVKGYPTI 469
+V FYAPWCGHCK PE+ KAA++ + + VD T DL ++V GYPT+
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 470 KYFSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
K F DY G +++ V ++ Q G
Sbjct: 256 KIFR--KGRPYDYNGPREKYGIVDYMIEQSG 284
Score = 141 bits (341), Expect = 8e-33
Identities = 81/212 (38%), Positives = 119/212 (56%), Gaps = 19/212 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK P+Y + A LK + I VAK S + ++++G+PT+
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKD--PPIPVAKIDATSASVLASRFDVSGYPTI 140
Query: 221 LYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV-VHLNGDSFD 279
++GQ Y G ++ IV +R+ V+QP W +V + L ++FD
Sbjct: 141 KILKKGQ-AVDYEGSRTQEEIVAKVRE-VSQP----------DWTPPPEVTLVLTKENFD 188
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
++ A+ LV FYAPWCGHCK++ PE+EKAA ++ LA VDAT E DLA RF
Sbjct: 189 EVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFD 248
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
V GYPTLK F KG +D R++ I+ ++
Sbjct: 249 VSGYPTLKIFRKGR-PYDYNGPREKYGIVDYM 279
Score = 99 bits (238), Expect = 2e-20
Identities = 62/226 (27%), Positives = 103/226 (45%), Gaps = 15/226 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDCTLHQ 455
L+ + F N + ++ FYAPWCGHCK PE+ K A D + + +D T
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSAS 126
Query: 456 DLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDA 515
L + ++V GYPTIK +AV DY G + + + V+ + T P+ T
Sbjct: 127 VLASRFDVSGYPTIKILKK-GQAV-DYEGSRTQEEIVAKVREVSQPDWTPP--PEVT--- 179
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
L+ ++F+++++ +V FYA WC HC P + + A L + P+
Sbjct: 180 ------LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++A A + PT K+F G+ DY+G R ++ +
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDY 278
Score = 69.3 bits (162), Expect = 4e-11
Identities = 36/104 (34%), Positives = 61/104 (58%), Gaps = 7/104 (6%)
Query: 275 GDSFDAILAKAEH-ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G +FD+I+ + L+ FYAPWCGHCK+++P + A K K +K ++A +DAT
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDV 590
Query: 334 LASRFGVKGYPTLKYFNKGE----FKFDAGHARQEDQIISFIKD 373
+ R+ V+G+PT+ + G+ KF+ G R + + FI++
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGD-RDLEHLSKFIEE 633
Score = 63.3 bits (147), Expect = 3e-09
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 521 VLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAA 580
VL+ D +F+ ++ ++ FYA WC HC P + ++A LK ++ P+ ++A
Sbjct: 64 VLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT 123
Query: 581 ENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
A + PT K+ G+ V DY+G R+ E+++
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV-DYEGSRTQEEIV 161
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK +P + A+++ + + +D T + Y V+G+PTI
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 470 KYFSYFDK--AVKDYTGGQKEGDFVSFIHNQMGTKQTSQK 507
+ DK VK + GG ++ + +S + TK + K
Sbjct: 604 YFAPSGDKKNPVK-FEGGDRDLEHLSKFIEEHATKLSRTK 642
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K +I FYAPWCG+CK ++P Y A KG+ L + N Y + GFPT+
Sbjct: 544 KDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTI 603
Query: 221 LYFERGQFRFPY---NGENKRQAIVEFMRDPVAQPKQKKKDV 259
+ G + P G+ + + +F+ + + + K+++
Sbjct: 604 YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 51.6 bits (118), Expect = 8e-06
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 529 FEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
F+ I+ P +++ FYA WC HC +P ++ LA K + V A ++A N +D
Sbjct: 535 FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIA-KMDATANDVPSD 593
Query: 588 FAGIQTLPTFKLFAAG--KYVTDYD-GDRSTEDLLKFCKRHA 626
++ PT +G K ++ GDR E L KF + HA
Sbjct: 594 RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHA 635
>D49489-1|BAA08450.1| 440|Homo sapiens human P5 protein.
Length = 440
Score = 137 bits (331), Expect = 1e-31
Identities = 84/251 (33%), Positives = 127/251 (50%), Gaps = 21/251 (8%)
Query: 260 VDESWARDTDVVHLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEK 318
V+ ++ DV+ L +F+ + +++ LV FYAPWCGHC+R+ PE++KAAT +K
Sbjct: 17 VNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVV 76
Query: 319 INGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFK---FDAGHARQE--DQIIS---- 369
G AVDA K L ++GV+G+PT+K F + + + G + D +S
Sbjct: 77 KVG---AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQ 133
Query: 370 FIKDXXXXXXXXXXX-----XXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHC 424
+KD + D S +N L +V FYAPWCGHC
Sbjct: 134 LVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHC 193
Query: 425 KSTKPEFVKAAEQFADEL--MVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
K+ +PE+ AA + ++ V AVD T++Q L + Y ++G+PTIK F + V DY
Sbjct: 194 KNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPV-DY 252
Query: 483 TGGQKEGDFVS 493
GG+ D VS
Sbjct: 253 DGGRTRSDIVS 263
Score = 134 bits (324), Expect = 9e-31
Identities = 79/220 (35%), Positives = 120/220 (54%), Gaps = 17/220 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG+C+ + P++ +AA LK + A+D K + + Y + GFPT+ F
Sbjct: 47 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK--HHSLGGQYGVQGFPTIKIF 104
Query: 224 ERGQFR-FPYNGENKRQAIVEFMRDPVAQPKQKK-----------KDVVDESWARDTDVV 271
+ R Y G +AIV+ + Q + + K +S ++ DV+
Sbjct: 105 GSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKK-DVI 163
Query: 272 HLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDAT 329
L DSFD + +E +V FYAPWCGHCK ++PE+ AA+++K + + LAAVDAT
Sbjct: 164 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT 223
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIIS 369
LASR+G++G+PT+K F KGE D R I+S
Sbjct: 224 VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 263
Score = 129 bits (311), Expect = 3e-29
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 394 VRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT 452
V L S F R ++ +V FYAPWCGHC+ PE+ KAA D +V GAVD
Sbjct: 27 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKD--VVKVGAVDAD 84
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFV--------SFIHNQMGTKQT 504
H L Y V+G+PTIK F +DY GG+ V + +++G +
Sbjct: 85 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 144
Query: 505 SQKAPKT-TQDAGFGANVLLAFDDDFEK-IISVPTPTIVMFYATWCSHCVTAKPAFSRLA 562
+ K D+ +V+ DD F+K ++ +V FYA WC HC +P ++ A
Sbjct: 145 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 204
Query: 563 TALKTENV-PVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
+ +K + VK A++A N A GI+ PT K+F G+ DYDG R+ D++
Sbjct: 205 SEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIV 262
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDL----KGESILAAIDVAKPGNSKIRQLYNITGFPT 219
M+ FYAPWCG+CK+++P++ AA ++ KG+ LAA+D N + Y I GFPT
Sbjct: 182 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATV--NQVLASRYGIRGFPT 239
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDS 277
+ F++G+ Y+G R IV D + P + ++++E A+ T H
Sbjct: 240 IKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQL--- 296
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++A H L A + + + K A K K + + A E + A
Sbjct: 297 --CVVAVLPHILDTGAAGRNSYLEVLL----KLADKYKKKMWGWLWTEAGAQSELETALG 350
Query: 338 FGVKGYPTLKYFNKGEFKF 356
G GYP + N + KF
Sbjct: 351 IGGFGYPAMAAINARKMKF 369
>BC001312-1|AAH01312.1| 440|Homo sapiens protein disulfide
isomerase family A, member 6 protein.
Length = 440
Score = 137 bits (331), Expect = 1e-31
Identities = 84/251 (33%), Positives = 127/251 (50%), Gaps = 21/251 (8%)
Query: 260 VDESWARDTDVVHLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEK 318
V+ ++ DV+ L +F+ + +++ LV FYAPWCGHC+R+ PE++KAAT +K
Sbjct: 17 VNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVV 76
Query: 319 INGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFK---FDAGHARQE--DQIIS---- 369
G AVDA K L ++GV+G+PT+K F + + + G + D +S
Sbjct: 77 KVG---AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQ 133
Query: 370 FIKDXXXXXXXXXXX-----XXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHC 424
+KD + D S +N L +V FYAPWCGHC
Sbjct: 134 LVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHC 193
Query: 425 KSTKPEFVKAAEQFADEL--MVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
K+ +PE+ AA + ++ V AVD T++Q L + Y ++G+PTIK F + V DY
Sbjct: 194 KNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPV-DY 252
Query: 483 TGGQKEGDFVS 493
GG+ D VS
Sbjct: 253 DGGRTRSDIVS 263
Score = 134 bits (324), Expect = 9e-31
Identities = 79/220 (35%), Positives = 120/220 (54%), Gaps = 17/220 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG+C+ + P++ +AA LK + A+D K + + Y + GFPT+ F
Sbjct: 47 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK--HHSLGGQYGVQGFPTIKIF 104
Query: 224 ERGQFR-FPYNGENKRQAIVEFMRDPVAQPKQKK-----------KDVVDESWARDTDVV 271
+ R Y G +AIV+ + Q + + K +S ++ DV+
Sbjct: 105 GSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKK-DVI 163
Query: 272 HLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDAT 329
L DSFD + +E +V FYAPWCGHCK ++PE+ AA+++K + + LAAVDAT
Sbjct: 164 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT 223
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIIS 369
LASR+G++G+PT+K F KGE D R I+S
Sbjct: 224 VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 263
Score = 129 bits (311), Expect = 3e-29
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 394 VRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT 452
V L S F R ++ +V FYAPWCGHC+ PE+ KAA D +V GAVD
Sbjct: 27 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKD--VVKVGAVDAD 84
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFV--------SFIHNQMGTKQT 504
H L Y V+G+PTIK F +DY GG+ V + +++G +
Sbjct: 85 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 144
Query: 505 SQKAPKT-TQDAGFGANVLLAFDDDFEK-IISVPTPTIVMFYATWCSHCVTAKPAFSRLA 562
+ K D+ +V+ DD F+K ++ +V FYA WC HC +P ++ A
Sbjct: 145 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 204
Query: 563 TALKTENV-PVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
+ +K + VK A++A N A GI+ PT K+F G+ DYDG R+ D++
Sbjct: 205 SEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIV 262
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDL----KGESILAAIDVAKPGNSKIRQLYNITGFPT 219
M+ FYAPWCG+CK+++P++ AA ++ KG+ LAA+D N + Y I GFPT
Sbjct: 182 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATV--NQVLASRYGIRGFPT 239
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDS 277
+ F++G+ Y+G R IV D + P + ++++E A+ T H
Sbjct: 240 IKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQL--- 296
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++A H L A + + + K A K K + + A E + A
Sbjct: 297 --CVVAVLPHILDTGAAGRNSYLEVLL----KLADKYKKKMWGWLWTEAGAQSELETALG 350
Query: 338 FGVKGYPTLKYFNKGEFKF 356
G GYP + N + KF
Sbjct: 351 IGGFGYPAMAAINARKMKF 369
>AK127433-1|BAC86977.1| 492|Homo sapiens protein ( Homo sapiens
cDNA FLJ45525 fis, clone BRTHA2026311, highly similar
to Protein disulfide isomerase A6 precursor (EC
5.3.4.1). ).
Length = 492
Score = 137 bits (331), Expect = 1e-31
Identities = 84/251 (33%), Positives = 127/251 (50%), Gaps = 21/251 (8%)
Query: 260 VDESWARDTDVVHLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEK 318
V+ ++ DV+ L +F+ + +++ LV FYAPWCGHC+R+ PE++KAAT +K
Sbjct: 69 VNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVV 128
Query: 319 INGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFK---FDAGHARQE--DQIIS---- 369
G AVDA K L ++GV+G+PT+K F + + + G + D +S
Sbjct: 129 KVG---AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQ 185
Query: 370 FIKDXXXXXXXXXXX-----XXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHC 424
+KD + D S +N L +V FYAPWCGHC
Sbjct: 186 LVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHC 245
Query: 425 KSTKPEFVKAAEQFADEL--MVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
K+ +PE+ AA + ++ V AVD T++Q L + Y ++G+PTIK F + V DY
Sbjct: 246 KNLEPEWAAAASEVKEQTKGRVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPV-DY 304
Query: 483 TGGQKEGDFVS 493
GG+ D VS
Sbjct: 305 DGGRTRSDIVS 315
Score = 134 bits (324), Expect = 9e-31
Identities = 79/220 (35%), Positives = 120/220 (54%), Gaps = 17/220 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG+C+ + P++ +AA LK + A+D K + + Y + GFPT+ F
Sbjct: 99 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK--HHSLGGQYGVQGFPTIKIF 156
Query: 224 ERGQFR-FPYNGENKRQAIVEFMRDPVAQPKQKK-----------KDVVDESWARDTDVV 271
+ R Y G +AIV+ + Q + + K +S ++ DV+
Sbjct: 157 GSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKK-DVI 215
Query: 272 HLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDAT 329
L DSFD + +E +V FYAPWCGHCK ++PE+ AA+++K + + LAAVDAT
Sbjct: 216 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGRVKLAAVDAT 275
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIIS 369
LASR+G++G+PT+K F KGE D R I+S
Sbjct: 276 VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 315
Score = 128 bits (310), Expect = 4e-29
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 394 VRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT 452
V L S F R ++ +V FYAPWCGHC+ PE+ KAA D +V GAVD
Sbjct: 79 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKD--VVKVGAVDAD 136
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFV--------SFIHNQMGTKQT 504
H L Y V+G+PTIK F +DY GG+ V + +++G +
Sbjct: 137 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 196
Query: 505 SQKAPKT-TQDAGFGANVLLAFDDDFEK-IISVPTPTIVMFYATWCSHCVTAKPAFSRLA 562
+ K D+ +V+ DD F+K ++ +V FYA WC HC +P ++ A
Sbjct: 197 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 256
Query: 563 TALKTENV-PVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
+ +K + VK A++A N A GI+ PT K+F G+ DYDG R+ D++
Sbjct: 257 SEVKEQTKGRVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIV 314
Score = 75.8 bits (178), Expect = 4e-13
Identities = 57/199 (28%), Positives = 90/199 (45%), Gaps = 17/199 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDL----KGESILAAIDVAKPGNSKIRQLYNITGFPT 219
M+ FYAPWCG+CK+++P++ AA ++ KG LAA+D N + Y I GFPT
Sbjct: 234 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGRVKLAAVDATV--NQVLASRYGIRGFPT 291
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDS 277
+ F++G+ Y+G R IV D + P + ++++E A+ T H
Sbjct: 292 IKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQL--- 348
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++A H L A + + + K A K K + + A E + A
Sbjct: 349 --CVVAVLPHILDTGAAGRNSYLEVLL----KLADKYKKKMWGWLWTEAGAQSELETALG 402
Query: 338 FGVKGYPTLKYFNKGEFKF 356
G GYP + N + KF
Sbjct: 403 IGGFGYPAMAAINARKMKF 421
>AC092687-3|AAY24070.1| 440|Homo sapiens unknown protein.
Length = 440
Score = 137 bits (331), Expect = 1e-31
Identities = 84/251 (33%), Positives = 127/251 (50%), Gaps = 21/251 (8%)
Query: 260 VDESWARDTDVVHLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEK 318
V+ ++ DV+ L +F+ + +++ LV FYAPWCGHC+R+ PE++KAAT +K
Sbjct: 17 VNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVV 76
Query: 319 INGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFK---FDAGHARQE--DQIIS---- 369
G AVDA K L ++GV+G+PT+K F + + + G + D +S
Sbjct: 77 KVG---AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQ 133
Query: 370 FIKDXXXXXXXXXXX-----XXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHC 424
+KD + D S +N L +V FYAPWCGHC
Sbjct: 134 LVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHC 193
Query: 425 KSTKPEFVKAAEQFADEL--MVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
K+ +PE+ AA + ++ V AVD T++Q L + Y ++G+PTIK F + V DY
Sbjct: 194 KNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPV-DY 252
Query: 483 TGGQKEGDFVS 493
GG+ D VS
Sbjct: 253 DGGRTRSDIVS 263
Score = 134 bits (324), Expect = 9e-31
Identities = 79/220 (35%), Positives = 120/220 (54%), Gaps = 17/220 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG+C+ + P++ +AA LK + A+D K + + Y + GFPT+ F
Sbjct: 47 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK--HHSLGGQYGVQGFPTIKIF 104
Query: 224 ERGQFR-FPYNGENKRQAIVEFMRDPVAQPKQKK-----------KDVVDESWARDTDVV 271
+ R Y G +AIV+ + Q + + K +S ++ DV+
Sbjct: 105 GSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKK-DVI 163
Query: 272 HLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDAT 329
L DSFD + +E +V FYAPWCGHCK ++PE+ AA+++K + + LAAVDAT
Sbjct: 164 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT 223
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIIS 369
LASR+G++G+PT+K F KGE D R I+S
Sbjct: 224 VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 263
Score = 129 bits (311), Expect = 3e-29
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 394 VRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT 452
V L S F R ++ +V FYAPWCGHC+ PE+ KAA D +V GAVD
Sbjct: 27 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKD--VVKVGAVDAD 84
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFV--------SFIHNQMGTKQT 504
H L Y V+G+PTIK F +DY GG+ V + +++G +
Sbjct: 85 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 144
Query: 505 SQKAPKT-TQDAGFGANVLLAFDDDFEK-IISVPTPTIVMFYATWCSHCVTAKPAFSRLA 562
+ K D+ +V+ DD F+K ++ +V FYA WC HC +P ++ A
Sbjct: 145 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 204
Query: 563 TALKTENV-PVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
+ +K + VK A++A N A GI+ PT K+F G+ DYDG R+ D++
Sbjct: 205 SEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIV 262
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDL----KGESILAAIDVAKPGNSKIRQLYNITGFPT 219
M+ FYAPWCG+CK+++P++ AA ++ KG+ LAA+D N + Y I GFPT
Sbjct: 182 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATV--NQVLASRYGIRGFPT 239
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDS 277
+ F++G+ Y+G R IV D + P + ++++E A+ T H
Sbjct: 240 IKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQL--- 296
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++A H L A + + + K A K K + + A E + A
Sbjct: 297 --CVVAVLPHILDTGAAGRNSYLEVLL----KLADKYKKKMWGWLWTEAGAQSELETALG 350
Query: 338 FGVKGYPTLKYFNKGEFKF 356
G GYP + N + KF
Sbjct: 351 IGGFGYPAMAAINARKMKF 369
>U79278-1|AAB50217.1| 421|Homo sapiens protein disulfide
isomerase-related protein 5 protein.
Length = 421
Score = 136 bits (330), Expect = 2e-31
Identities = 83/247 (33%), Positives = 125/247 (50%), Gaps = 21/247 (8%)
Query: 264 WARDTDVVHLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI 322
++ DV+ L +F+ + +++ LV FYAPWCGHC+R+ PE++KAAT +K G
Sbjct: 2 YSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG- 60
Query: 323 LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFK---FDAGHARQE--DQIIS----FIKD 373
AVDA K L ++GV+G+PT+K F + + + G + D +S +KD
Sbjct: 61 --AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKD 118
Query: 374 XXXXXXXXXXX-----XXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTK 428
+ D S +N L +V FYAPWCGHCK+ +
Sbjct: 119 RLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLE 178
Query: 429 PEFVKAAEQFADEL--MVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQ 486
PE+ AA + ++ V AVD T++Q L + Y ++G+PTIK F + V DY GG+
Sbjct: 179 PEWAAAASEVKEQTKGRVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPV-DYDGGR 237
Query: 487 KEGDFVS 493
D VS
Sbjct: 238 TRSDIVS 244
Score = 134 bits (324), Expect = 9e-31
Identities = 79/220 (35%), Positives = 120/220 (54%), Gaps = 17/220 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG+C+ + P++ +AA LK + A+D K + + Y + GFPT+ F
Sbjct: 28 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK--HHSLGGQYGVQGFPTIKIF 85
Query: 224 ERGQFR-FPYNGENKRQAIVEFMRDPVAQPKQKK-----------KDVVDESWARDTDVV 271
+ R Y G +AIV+ + Q + + K +S ++ DV+
Sbjct: 86 GSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKK-DVI 144
Query: 272 HLNGDSFDAILAKAEHA-LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDAT 329
L DSFD + +E +V FYAPWCGHCK ++PE+ AA+++K + + LAAVDAT
Sbjct: 145 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGRVKLAAVDAT 204
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIIS 369
LASR+G++G+PT+K F KGE D R I+S
Sbjct: 205 VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 244
Score = 128 bits (310), Expect = 4e-29
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 394 VRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCT 452
V L S F R ++ +V FYAPWCGHC+ PE+ KAA D +V GAVD
Sbjct: 8 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKD--VVKVGAVDAD 65
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFV--------SFIHNQMGTKQT 504
H L Y V+G+PTIK F +DY GG+ V + +++G +
Sbjct: 66 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 125
Query: 505 SQKAPKT-TQDAGFGANVLLAFDDDFEK-IISVPTPTIVMFYATWCSHCVTAKPAFSRLA 562
+ K D+ +V+ DD F+K ++ +V FYA WC HC +P ++ A
Sbjct: 126 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 185
Query: 563 TALKTENV-PVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLL 619
+ +K + VK A++A N A GI+ PT K+F G+ DYDG R+ D++
Sbjct: 186 SEVKEQTKGRVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIV 243
Score = 75.8 bits (178), Expect = 4e-13
Identities = 57/199 (28%), Positives = 90/199 (45%), Gaps = 17/199 (8%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDL----KGESILAAIDVAKPGNSKIRQLYNITGFPT 219
M+ FYAPWCG+CK+++P++ AA ++ KG LAA+D N + Y I GFPT
Sbjct: 163 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGRVKLAAVDATV--NQVLASRYGIRGFPT 220
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDS 277
+ F++G+ Y+G R IV D + P + ++++E A+ T H
Sbjct: 221 IKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQL--- 277
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++A H L A + + + K A K K + + A E + A
Sbjct: 278 --CVVAVLPHILDTGAAGRNSYLEVLL----KLADKYKKKMWGWLWTEAGAQSELETALG 331
Query: 338 FGVKGYPTLKYFNKGEFKF 356
G GYP + N + KF
Sbjct: 332 IGGFGYPAMAAINARKMKF 350
>BC001199-1|AAH01199.1| 324|Homo sapiens TXNDC5 protein protein.
Length = 324
Score = 132 bits (319), Expect = 4e-30
Identities = 90/322 (27%), Positives = 140/322 (43%), Gaps = 17/322 (5%)
Query: 323 LAAVDATKEPDLASRFGVKGYPTLKYFNKGE--FKFDAGHARQ--EDQIISFIKDXXXXX 378
+A VD T D+ S GV+GYPTLK F G+ K+ Q E+ ++ + +
Sbjct: 8 VAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTP 67
Query: 379 XXXXXXXXXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF 438
+ L +S F + + H + F+APWCGHCK+ P + + A
Sbjct: 68 EPEVEPPSAPELKQGLYELSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGL 126
Query: 439 ADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
V G VDCT H +LC+ V+GYPT+ +F K V Y G + ++ +Q
Sbjct: 127 EHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQ 185
Query: 499 MGTKQTSQKAPKTTQDAGFGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSH 550
+ +T T +A A VL +++F+ I+ T + FYA WC H
Sbjct: 186 LQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGH 244
Query: 551 CVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYD 610
C T P + L+ VK ++ ++ PT LF GK V+++
Sbjct: 245 CKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHS 304
Query: 611 GDRSTEDLLKFCKRHAEVKDEL 632
G R + L +F ++ KDEL
Sbjct: 305 GGRDLDSLHRFVL--SQAKDEL 324
Score = 125 bits (301), Expect = 5e-28
Identities = 81/310 (26%), Positives = 148/310 (47%), Gaps = 22/310 (7%)
Query: 205 NSKIRQLYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESW 264
+S + + G+PTL F+ GQ Y G Q + +M + + + V+
Sbjct: 16 HSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPS 75
Query: 265 ARD--TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIK-TEKING 321
A + + L+ +F+ +A+ +H + F+APWCGHCK + P +E+ A ++ +E +
Sbjct: 76 APELKQGLYELSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVK- 133
Query: 322 ILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQE-DQIISFIKDXXXXXXX 380
+ VD T+ +L S V+GYPTL +F G+ K D +++ + + +++
Sbjct: 134 -IGKVDCTQHYELCSGNQVRGYPTLLWFRDGK-KVDQYKGKRDLESLREYVESQLQRTET 191
Query: 381 XXXXXXX-----------XXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKP 429
V L + F +T+ + + + FYAPWCGHCK+ P
Sbjct: 192 GATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAE-GITFIKFYAPWCGHCKTLAP 250
Query: 430 EFVK-AAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
+ + + ++F V VDCT +++C+ Y+V+GYPT+ F K V +++GG+
Sbjct: 251 TWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFR-GGKKVSEHSGGRDL 309
Query: 489 GDFVSFIHNQ 498
F+ +Q
Sbjct: 310 DSLHRFVLSQ 319
Score = 109 bits (261), Expect = 4e-23
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 21/291 (7%)
Query: 97 LKHYKDGDFNKDYDRSESVSSMCNFL-----RDPTGDLPWEEDPTAVDIYHLLDGEAIVK 151
LK +K G Y ++ N++ +P P E P+A ++ L +
Sbjct: 31 LKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASN 90
Query: 152 F-LKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQ 210
F L G H I F+APWCG+CK++ P + + A L+ + V + ++
Sbjct: 91 FELHVAQGDH---FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCS 147
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWAR---- 266
+ G+PTLL+F G+ Y G+ +++ E++ + + + + V S A
Sbjct: 148 GNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAA 207
Query: 267 --DTD---VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
+ D V+ L ++FD +A+ + FYAPWCGHCK + P +E+ + K + + G
Sbjct: 208 EPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAG 265
Query: 322 I-LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
+ +A VD T E ++ S++ V+GYPTL F G+ + R D + F+
Sbjct: 266 VKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 316
Score = 72.1 bits (169), Expect = 5e-12
Identities = 51/185 (27%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 440 DELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGG---QKEGDFVSFIH 496
++ V VDCT H D+C+ V+GYPT+K F +AVK Y G Q +++
Sbjct: 2 EDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVK-YQGPRDFQTLENWMLQTL 60
Query: 497 NQMGTKQTSQKAPKTTQDAGFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKP 556
N+ + P + + G L A +FE ++ + F+A WC HC P
Sbjct: 61 NEEPVTPEPEVEPPSAPELKQGLYELSA--SNFELHVA-QGDHFIKFFAPWCGHCKALAP 117
Query: 557 AFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTE 616
+ +LA L+ + VK ++ ++ + ++ PT F GK V Y G R E
Sbjct: 118 TWEQLALGLE-HSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLE 176
Query: 617 DLLKF 621
L ++
Sbjct: 177 SLREY 181
>AL834423-1|CAD39084.1| 244|Homo sapiens hypothetical protein
protein.
Length = 244
Score = 113 bits (273), Expect = 1e-24
Identities = 71/244 (29%), Positives = 110/244 (45%), Gaps = 13/244 (5%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQD 456
L +S F + + H + F+APWCGHCK+ P + + A V G VDCT H +
Sbjct: 6 LSASNFELHVAQGDH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYE 64
Query: 457 LCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAG 516
LC+ V+GYPT+ +F K V Y G + ++ +Q+ +T T +A
Sbjct: 65 LCSGNQVRGYPTLLWFR-DGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAP 123
Query: 517 FGA--------NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTE 568
A VL +++F+ I+ T + FYA WC HC T P + L+
Sbjct: 124 VLAAEPEADKGTVLALTENNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKKEFPG 182
Query: 569 NVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHAEV 628
VK ++ ++ PT LF GK V+++ G R + L +F ++
Sbjct: 183 LAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVL--SQA 240
Query: 629 KDEL 632
KDEL
Sbjct: 241 KDEL 244
Score = 105 bits (253), Expect = 4e-22
Identities = 63/217 (29%), Positives = 112/217 (51%), Gaps = 12/217 (5%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
I F+APWCG+CK++ P + + A L+ + V + ++ + G+PTLL+F
Sbjct: 22 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR 81
Query: 225 RGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWAR------DTD---VVHLNG 275
G+ Y G+ +++ E++ + + + + V S A + D V+ L
Sbjct: 82 DGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTE 141
Query: 276 DSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-LAAVDATKEPDL 334
++FD +A+ + FYAPWCGHCK + P +E+ + K + + G+ +A VD T E ++
Sbjct: 142 NNFDDTIAEGI-TFIKFYAPWCGHCKTLAPTWEELSKK-EFPGLAGVKIAEVDCTAERNI 199
Query: 335 ASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFI 371
S++ V+GYPTL F G+ + R D + F+
Sbjct: 200 CSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFV 236
Score = 51.6 bits (118), Expect = 8e-06
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVE-AAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLL 221
+ I FYAPWCG+CK++ P + E + + G + + +V I Y++ G+PTLL
Sbjct: 153 TFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLL 212
Query: 222 YFERGQFRFPYNGENKRQAIVEFM 245
F G+ ++G ++ F+
Sbjct: 213 LFRGGKKVSEHSGGRDLDSLHRFV 236
>BC126168-1|AAI26169.1| 793|Homo sapiens DnaJ (Hsp40) homolog,
subfamily C, member 10 protein.
Length = 793
Score = 108 bits (260), Expect = 5e-23
Identities = 78/323 (24%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 529
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 530 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 571
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 628
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K A Q + +D L
Sbjct: 629 QRYPEIRFFPPKSNK-----AYQYHSYNGWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 678
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 679 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 736
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 737 KAGIRAYPTVKFY-FYERAKRNF 758
Score = 104 bits (249), Expect = 1e-21
Identities = 86/316 (27%), Positives = 135/316 (42%), Gaps = 42/316 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 528
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 529 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 572
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 573 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 630
Query: 466 YPTIKYFS-YFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVLLA 524
YP I++F +KA + ++ D S +G P+ + D L
Sbjct: 631 YPEIRFFPPKSNKAYQYHSYNGWNRDAYSLRIWGLGF------LPQVSTD--------LT 676
Query: 525 FDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
EK++ ++ FYA WC C P F LA +K + VKA ++ +
Sbjct: 677 PQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYAQ 733
Query: 585 AADFAGIQTLPTFKLF 600
AGI+ PT K +
Sbjct: 734 TCQKAGIRAYPTVKFY 749
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 749
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 750 FYERAKRNFQEEQINTRDA 768
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 470 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 526
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 527 VVFNQSN-IHEYEGHHSAEQILEF 549
>BC117299-1|AAI17300.1| 793|Homo sapiens DnaJ (Hsp40) homolog,
subfamily C, member 10 protein.
Length = 793
Score = 108 bits (260), Expect = 5e-23
Identities = 78/323 (24%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 529
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 530 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 571
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 628
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K A Q + +D L
Sbjct: 629 QRYPEIRFFPPKSNK-----AYQYHSYNGWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 678
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 679 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 736
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 737 KAGIRAYPTVKFY-FYERAKRNF 758
Score = 104 bits (249), Expect = 1e-21
Identities = 86/316 (27%), Positives = 135/316 (42%), Gaps = 42/316 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 528
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 529 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 572
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 573 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 630
Query: 466 YPTIKYFS-YFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVLLA 524
YP I++F +KA + ++ D S +G P+ + D L
Sbjct: 631 YPEIRFFPPKSNKAYQYHSYNGWNRDAYSLRIWGLGF------LPQVSTD--------LT 676
Query: 525 FDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
EK++ ++ FYA WC C P F LA +K + VKA ++ +
Sbjct: 677 PQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYAQ 733
Query: 585 AADFAGIQTLPTFKLF 600
AGI+ PT K +
Sbjct: 734 TCQKAGIRAYPTVKFY 749
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 749
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 750 FYERAKRNFQEEQINTRDA 768
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 470 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 526
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 527 VVFNQSN-IHEYEGHHSAEQILEF 549
>AY358577-1|AAQ88940.1| 747|Homo sapiens disulfide isomerase
protein.
Length = 747
Score = 108 bits (260), Expect = 5e-23
Identities = 78/323 (24%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 426 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 483
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 484 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 525
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 526 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 582
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K A Q + +D L
Sbjct: 583 QRYPEIRFFPPKSNK-----AYQYHSYNGWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 632
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 633 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 690
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 691 KAGIRAYPTVKFY-FYERAKRNF 712
Score = 104 bits (249), Expect = 1e-21
Identities = 86/316 (27%), Positives = 135/316 (42%), Gaps = 42/316 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 426 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 482
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 483 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 526
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 527 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 584
Query: 466 YPTIKYFS-YFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVLLA 524
YP I++F +KA + ++ D S +G P+ + D L
Sbjct: 585 YPEIRFFPPKSNKAYQYHSYNGWNRDAYSLRIWGLGF------LPQVSTD--------LT 630
Query: 525 FDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
EK++ ++ FYA WC C P F LA +K + VKA ++ +
Sbjct: 631 PQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYAQ 687
Query: 585 AADFAGIQTLPTFKLF 600
AGI+ PT K +
Sbjct: 688 TCQKAGIRAYPTVKFY 703
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 646 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 703
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 704 FYERAKRNFQEEQINTRDA 722
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 424 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 480
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 481 VVFNQSN-IHEYEGHHSAEQILEF 503
>AL832646-1|CAD89982.1| 792|Homo sapiens hypothetical protein
protein.
Length = 792
Score = 108 bits (260), Expect = 5e-23
Identities = 78/323 (24%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 471 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 528
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 529 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTAFNELVT 570
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 571 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 627
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K A Q + +D L
Sbjct: 628 QRYPEIRFFPPKSNK-----AYQYHSYNGWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 677
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 678 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 735
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 736 KAGIRAYPTVKFY-FYERAKRNF 757
Score = 102 bits (244), Expect = 4e-21
Identities = 85/316 (26%), Positives = 134/316 (42%), Gaps = 42/316 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 471 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 527
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L + F + +
Sbjct: 528 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTAFNELVTQ 571
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 572 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 629
Query: 466 YPTIKYFS-YFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVLLA 524
YP I++F +KA + ++ D S +G P+ + D L
Sbjct: 630 YPEIRFFPPKSNKAYQYHSYNGWNRDAYSLRIWGLGF------LPQVSTD--------LT 675
Query: 525 FDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
EK++ ++ FYA WC C P F LA +K + VKA ++ +
Sbjct: 676 PQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYAQ 732
Query: 585 AADFAGIQTLPTFKLF 600
AGI+ PT K +
Sbjct: 733 TCQKAGIRAYPTVKFY 748
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 127 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 181
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 182 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 227
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 137 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 193
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 194 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 231
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 150 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 207
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 208 SGMAPVKYHGDRSKESLVSF 227
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 150 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 207
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 208 SGMAPVK-YHGDRSKESLVSF 227
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 691 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 748
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 749 FYERAKRNFQEEQINTRDA 767
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 469 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 525
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 526 VVFNQSN-IHEYEGHHSAEQILEF 548
>AL137648-1|CAB70858.1| 464|Homo sapiens hypothetical protein
protein.
Length = 464
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 143 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 200
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 201 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 242
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 243 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 299
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 300 QRYPKIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 349
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 350 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 407
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 408 KAGIRAYPTVKFY-FYERAKRNF 429
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 143 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 199
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 200 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 243
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 244 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 301
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 302 YPKIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 346
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 347 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 403
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 404 QTCQKAGIRAYPTVKFY 420
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 363 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 420
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 421 FYERAKRNFQEEQINTRDA 439
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 141 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 197
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 198 VVFNQSN-IHEYEGHHSAEQILEF 220
>AK027647-1|BAB55263.1| 793|Homo sapiens protein ( Homo sapiens
cDNA FLJ14741 fis, clone NT2RP3002628, weakly similar to
PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR (EC
5.3.4.1). ).
Length = 793
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 529
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 530 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 571
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 628
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 629 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 678
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 679 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 736
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 737 KAGIRAYPTVKFY-FYERAKRNF 758
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 528
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 529 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 572
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 573 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 630
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 631 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 675
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 676 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 732
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 733 QTCQKAGIRAYPTVKFY 749
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 749
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 750 FYERAKRNFQEEQINTRDA 768
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 470 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 526
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 527 VVFNQSN-IHEYEGHHSAEQILEF 549
>AK027450-1|BAB55121.1| 768|Homo sapiens protein ( Homo sapiens
cDNA FLJ14544 fis, clone NT2RM2001547, weakly similar to
PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR (EC
5.3.4.1). ).
Length = 768
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 447 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 504
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 505 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 546
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 547 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 603
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 604 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 653
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 654 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 711
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 712 KAGIRAYPTVKFY-FYERAKRNF 733
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 447 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 503
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 504 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 547
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 548 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 605
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 606 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 650
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 651 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 707
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 708 QTCQKAGIRAYPTVKFY 724
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 103 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 157
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 158 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 203
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 113 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 169
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 170 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 207
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 126 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 183
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 184 SGMAPVKYHGDRSKESLVSF 203
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 126 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 183
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 184 SGMAPVK-YHGDRSKESLVSF 203
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 667 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 724
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 725 FYERAKRNFQEEQINTRDA 743
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 445 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 501
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 502 VVFNQSN-IHEYEGHHSAEQILEF 524
>AF490904-1|AAM09527.1| 747|Homo sapiens macrothioredoxin protein.
Length = 747
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 426 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 483
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 484 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 525
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 526 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 582
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 583 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 632
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 633 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 690
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 691 KAGIRAYPTVKFY-FYERAKRNF 712
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 426 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 482
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 483 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 526
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 527 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 584
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 585 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 629
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 630 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 686
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 687 QTCQKAGIRAYPTVKFY 703
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 646 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 703
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 704 FYERAKRNFQEEQINTRDA 722
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 424 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 480
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 481 VVFNQSN-IHEYEGHHSAEQILEF 503
>AF038503-1|AAN73271.1| 793|Homo sapiens ER-resident protein ERdj5
protein.
Length = 793
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 529
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 530 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 571
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 628
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 629 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 678
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 679 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 736
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 737 KAGIRAYPTVKFY-FYERAKRNF 758
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 528
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 529 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 572
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 573 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 630
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 631 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 675
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 676 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 732
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 733 QTCQKAGIRAYPTVKFY 749
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAAVKYHGDRSKESLVSF 228
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAAVKYHGDRSKESLVSFAMQH 232
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
AVK Y G + + VSF
Sbjct: 209 SGMAAVK-YHGDRSKESLVSF 228
Score = 43.2 bits (97), Expect = 0.003
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAAVKYHGDRSKESLVSF 228
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 749
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 750 FYERAKRNFQEEQINTRDA 768
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 470 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 526
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 527 VVFNQSN-IHEYEGHHSAEQILEF 549
>AC105396-1|AAY24240.1| 464|Homo sapiens unknown protein.
Length = 464
Score = 107 bits (257), Expect = 1e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 143 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 200
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 201 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 242
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 243 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 299
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 300 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 349
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 350 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 407
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 408 KAGIRAYPTVKFY-FYERAKRNF 429
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 143 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 199
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 200 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 243
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 244 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 301
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 302 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 346
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 347 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 403
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 404 QTCQKAGIRAYPTVKFY 420
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 363 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 420
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 421 FYERAKRNFQEEQINTRDA 439
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 141 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 197
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 198 VVFNQSN-IHEYEGHHSAEQILEF 220
>AK027696-1|BAB55304.1| 793|Homo sapiens protein ( Homo sapiens
cDNA FLJ14790 fis, clone NT2RP4000973, weakly similar to
PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR (EC
5.3.4.1). ).
Length = 793
Score = 107 bits (256), Expect = 2e-22
Identities = 77/323 (23%), Positives = 145/323 (44%), Gaps = 40/323 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APWC C+++ P+ A+ L G+ +D + + +YNI +PT + F
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTV--HEGLCNMYNIQAYPTTVVF 529
Query: 224 ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILA 283
+ Y G + + I+EF+ D + + VV L +F+ ++
Sbjct: 530 NQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSVVSLTPTTFNELVT 571
Query: 284 KAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGV 340
+ +H +V FY+PWC C+ + PE+++ A + T IN + ++D + ++ V
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSIDCQQYHSFCAQENV 628
Query: 341 KGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSS 400
+ YP +++F K H+ + +D L
Sbjct: 629 QRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQVSTD-----LTPQ 678
Query: 401 TF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCA 459
TF L+ H ++ FYAPWCG C++ PEF A + V G VDC + C
Sbjct: 679 TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTCQ 736
Query: 460 NYNVKGYPTIKYFSYFDKAVKDY 482
++ YPT+K++ ++++A +++
Sbjct: 737 KAGIRAYPTVKFY-FYERANRNF 758
Score = 103 bits (248), Expect = 1e-21
Identities = 87/317 (27%), Positives = 133/317 (41%), Gaps = 44/317 (13%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV F+APWC C+ + PE +A+ + + G L D T L + + ++ YPT
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL---DCTVHEGLCNMYNIQAYPTTVV 528
Query: 349 FNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHLDSSTFRNTLRK 408
FN+ GH E QI+ FI+D V L +TF + +
Sbjct: 529 FNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSLTPTTFNELVTQ 572
Query: 409 IKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKG 465
KH+ +V FY+PWC C+ PE+ + A ++ G++DC + CA NV+
Sbjct: 573 RKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQYHSFCAQENVQR 630
Query: 466 YPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQDAGFGANVL--L 523
YP I++F K+ K Y H+ G + + GF V L
Sbjct: 631 YPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWGLGFLPQVSTDL 675
Query: 524 AFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENP 583
EK++ ++ FYA WC C P F LA +K + VKA ++
Sbjct: 676 TPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYA 732
Query: 584 KAADFAGIQTLPTFKLF 600
+ AGI+ PT K +
Sbjct: 733 QTCQKAGIRAYPTVKFY 749
Score = 66.9 bits (156), Expect = 2e-10
Identities = 53/208 (25%), Positives = 91/208 (43%), Gaps = 28/208 (13%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
M+ FY+PWC C+ + P++ A L G + +ID + + ++ N+ +P + +F
Sbjct: 580 MVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQE--NVQRYPEIRFF 637
Query: 224 ----ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFD 279
+ YNG N+ + + Q D+ ++++ +
Sbjct: 638 PPKSNKAYHYHSYNGWNRDAYSLRIWG--LGFLPQVSTDLTPQTFS-------------E 682
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
+L H ++ FYAPWCG C+ PEFE A IK + G VD + G
Sbjct: 683 KVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAG---KVDCQAYAQTCQKAG 739
Query: 340 VKGYPTLKYFNKGEFKFDAGHARQEDQI 367
++ YPT+K++ F A QE+QI
Sbjct: 740 IRAYPTVKFY----FYERANRNFQEEQI 763
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 749
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER F N R A
Sbjct: 750 FYERANRNFQEEQINTRDA 768
Score = 38.3 bits (85), Expect = 0.082
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 538 PTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTF 597
P +V F+A WC C P R + L + +K L+ + + IQ PT
Sbjct: 470 PWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTT 526
Query: 598 KLFAAGKYVTDYDGDRSTEDLLKF 621
+F + +Y+G S E +L+F
Sbjct: 527 VVFNQSN-IHEYEGHHSAEQILEF 549
>J02783-1|AAA61169.1| 508|Homo sapiens P4HB protein.
Length = 508
Score = 103 bits (247), Expect = 2e-21
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ LV FYAPWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLR-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 90.6 bits (215), Expect = 1e-17
Identities = 111/479 (23%), Positives = 197/479 (41%), Gaps = 65/479 (13%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK ++ FYAPWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHL 273
G+PT+ +F G P Y + IV ++ KK+ + RD
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWL---------KKRTGPAATTLRD------ 142
Query: 274 NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
G + ++++ +E A++ F+ K ++ + K + E I+ I + T D
Sbjct: 143 -GAAAESLVESSEVAVIGFF-------KDVESDSAKQFLQA-AEAIDDIPFGI--TSNSD 191
Query: 334 LASRFGVK--GYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXX 391
+ S++ + G K F++G F+ G +E+ ++ FIK
Sbjct: 192 VFSKYQLDKDGVVLFKKFDEGRNNFE-GEVTKEN-LLDFIKHNQLPLV------------ 237
Query: 392 XXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+ + + + +IK I++F F AAE F +++ F D
Sbjct: 238 --IEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDH 295
Query: 452 TLHQDLCANYNVKGY--PTIKYFSYFDKAVKDYTGGQKE---GDFVSFIHNQMGTKQTSQ 506
T +Q + + +K P ++ + ++ K Y +E F H + K
Sbjct: 296 TDNQRILEFFGLKKEECPAVRLITLEEEMTK-YKPESEELTAERITEFCHRFLEGKIKPH 354
Query: 507 KAPKTTQDAGFGANVLLAFDDDFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATAL 565
+ V + +FE + + V FYA WC HC P + +L
Sbjct: 355 LMSQERAGDWDKQPVKVPVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETY 414
Query: 566 KT-ENVPVKAVALEAAENPKAADFAGIQTLPTFKLF--AAGKYVTDYDGDRSTEDLLKF 621
K EN+ + + A E + + + PT K F +A + V DY+G+R+ + KF
Sbjct: 415 KDHENIVIAKMDSTANE----VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ +V FYA WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 57.2 bits (132), Expect = 2e-07
Identities = 56/254 (22%), Positives = 102/254 (40%), Gaps = 31/254 (12%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FL----------RDPTGDLPWEEDPTAV 138
+ + + K SE ++ C+ FL ++ GD W++ P V
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQERAGD--WDKQPVKV 371
Query: 139 DIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAI 198
+ + V F +K K + FYAPWCG+CK + P + + K +
Sbjct: 372 PVGKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIA 423
Query: 199 DVAKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKK 256
+ N + + FPTL +F R YNGE +F+
Sbjct: 424 KMDSTANEV--EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDD 481
Query: 257 KDVVDESWARDTDV 270
D+ D A + D+
Sbjct: 482 DDLEDLEEAEEPDM 495
>M22806-1|AAC13652.1| 508|Homo sapiens prolyl 4-hydroxylase
beta-subunit protein.
Length = 508
Score = 103 bits (246), Expect = 3e-21
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ LV FYAPWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLP-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 72.1 bits (169), Expect = 5e-12
Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK ++ FYAPWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMR 246
G+PT+ +F G P Y + IV +++
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ +V FYA WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 60.1 bits (139), Expect = 2e-08
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 181 DYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPT--LLYFERGQFRF-PYNGE 235
++ AA KG+ + ID N +I + + + P L+ E ++ P + E
Sbjct: 274 NFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEE 333
Query: 236 NKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALVVF 292
+ I EF + +P +++ E W + V + + D + ++ V F
Sbjct: 334 LTAERITEFCHRFLEGKIKPHLMSQEL-PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 392
Query: 293 YAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYF 349
YAPWCGHCK++ P ++K K + N ++A +D+T A + V +PTLK+F
Sbjct: 393 YAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTANEVEAVK--VHSFPTLKFF 446
Score = 58.0 bits (134), Expect = 9e-08
Identities = 56/252 (22%), Positives = 102/252 (40%), Gaps = 27/252 (10%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FLRDP------TGDLP--WEEDPTAVDI 140
+ + + K SE ++ C+ FL + +LP W++ P V +
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLV 373
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
+ V F +K K + FYAPWCG+CK + P + + K + +
Sbjct: 374 GKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKD 258
N + + FPTL +F R YNGE +F+ D
Sbjct: 426 DSTANEV--EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDD 483
Query: 259 VVDESWARDTDV 270
+ D A + D+
Sbjct: 484 LEDLEEAEEPDM 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 20/226 (8%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGY- 466
+IK I++F F AAE F +++ F D T +Q + + +K
Sbjct: 252 EIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEE 311
Query: 467 -PTIKYFSYFDKAVK-----DYTGGQKEGDFVS-FIHNQMGTKQTSQKAPKTTQDAGFGA 519
P ++ + ++ K + ++ +F F+ ++ SQ+ P+
Sbjct: 312 CPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKV 371
Query: 520 NVLLAFDD-DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVAL 577
V F+D F++ +V V FYA WC HC P + +L K EN+ + +
Sbjct: 372 LVGKNFEDVAFDEKKNV----FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
Query: 578 EAAENPKAADFAGIQTLPTFKLF--AAGKYVTDYDGDRSTEDLLKF 621
A E + + + PT K F +A + V DY+G+R+ + KF
Sbjct: 428 TANE----VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
>BC071892-1|AAH71892.1| 508|Homo sapiens procollagen-proline,
2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),
beta protein.
Length = 508
Score = 103 bits (246), Expect = 3e-21
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ LV FYAPWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLP-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 72.1 bits (169), Expect = 5e-12
Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK ++ FYAPWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMR 246
G+PT+ +F G P Y + IV +++
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ +V FYA WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 60.1 bits (139), Expect = 2e-08
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 181 DYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPT--LLYFERGQFRF-PYNGE 235
++ AA KG+ + ID N +I + + + P L+ E ++ P + E
Sbjct: 274 NFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEE 333
Query: 236 NKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALVVF 292
+ I EF + +P +++ E W + V + + D + ++ V F
Sbjct: 334 LTAERITEFCHRFLEGKIKPHLMSQEL-PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 392
Query: 293 YAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYF 349
YAPWCGHCK++ P ++K K + N ++A +D+T A + V +PTLK+F
Sbjct: 393 YAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTANEVEAVK--VHSFPTLKFF 446
Score = 58.0 bits (134), Expect = 9e-08
Identities = 56/252 (22%), Positives = 102/252 (40%), Gaps = 27/252 (10%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FLRDP------TGDLP--WEEDPTAVDI 140
+ + + K SE ++ C+ FL + +LP W++ P V +
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLV 373
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
+ V F +K K + FYAPWCG+CK + P + + K + +
Sbjct: 374 GKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKD 258
N + + FPTL +F R YNGE +F+ D
Sbjct: 426 DSTANEV--EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDD 483
Query: 259 VVDESWARDTDV 270
+ D A + D+
Sbjct: 484 LEDLEEAEEPDM 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 20/226 (8%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGY- 466
+IK I++F F AAE F +++ F D T +Q + + +K
Sbjct: 252 EIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEE 311
Query: 467 -PTIKYFSYFDKAVK-----DYTGGQKEGDFVS-FIHNQMGTKQTSQKAPKTTQDAGFGA 519
P ++ + ++ K + ++ +F F+ ++ SQ+ P+
Sbjct: 312 CPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKV 371
Query: 520 NVLLAFDD-DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVAL 577
V F+D F++ +V V FYA WC HC P + +L K EN+ + +
Sbjct: 372 LVGKNFEDVAFDEKKNV----FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
Query: 578 EAAENPKAADFAGIQTLPTFKLF--AAGKYVTDYDGDRSTEDLLKF 621
A E + + + PT K F +A + V DY+G+R+ + KF
Sbjct: 428 TANE----VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
>BC029617-1|AAH29617.1| 508|Homo sapiens procollagen-proline,
2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),
beta protein.
Length = 508
Score = 103 bits (246), Expect = 3e-21
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ LV FYAPWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLP-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 72.1 bits (169), Expect = 5e-12
Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK ++ FYAPWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMR 246
G+PT+ +F G P Y + IV +++
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ +V FYA WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 60.1 bits (139), Expect = 2e-08
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 181 DYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPT--LLYFERGQFRF-PYNGE 235
++ AA KG+ + ID N +I + + + P L+ E ++ P + E
Sbjct: 274 NFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEE 333
Query: 236 NKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALVVF 292
+ I EF + +P +++ E W + V + + D + ++ V F
Sbjct: 334 LTAERITEFCHRFLEGKIKPHLMSQEL-PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 392
Query: 293 YAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYF 349
YAPWCGHCK++ P ++K K + N ++A +D+T A + V +PTLK+F
Sbjct: 393 YAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTANEVEAVK--VHSFPTLKFF 446
Score = 58.0 bits (134), Expect = 9e-08
Identities = 56/252 (22%), Positives = 102/252 (40%), Gaps = 27/252 (10%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FLRDP------TGDLP--WEEDPTAVDI 140
+ + + K SE ++ C+ FL + +LP W++ P V +
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLV 373
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
+ V F +K K + FYAPWCG+CK + P + + K + +
Sbjct: 374 GKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKD 258
N + + FPTL +F R YNGE +F+ D
Sbjct: 426 DSTANEV--EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDD 483
Query: 259 VVDESWARDTDV 270
+ D A + D+
Sbjct: 484 LEDLEEAEEPDM 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 20/226 (8%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGY- 466
+IK I++F F AAE F +++ F D T +Q + + +K
Sbjct: 252 EIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEE 311
Query: 467 -PTIKYFSYFDKAVK-----DYTGGQKEGDFVS-FIHNQMGTKQTSQKAPKTTQDAGFGA 519
P ++ + ++ K + ++ +F F+ ++ SQ+ P+
Sbjct: 312 CPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKV 371
Query: 520 NVLLAFDD-DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVAL 577
V F+D F++ +V V FYA WC HC P + +L K EN+ + +
Sbjct: 372 LVGKNFEDVAFDEKKNV----FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
Query: 578 EAAENPKAADFAGIQTLPTFKLF--AAGKYVTDYDGDRSTEDLLKF 621
A E + + + PT K F +A + V DY+G+R+ + KF
Sbjct: 428 TANE----VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
>BC010859-1|AAH10859.1| 508|Homo sapiens procollagen-proline,
2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),
beta protein.
Length = 508
Score = 103 bits (246), Expect = 3e-21
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ LV FYAPWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLP-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 72.1 bits (169), Expect = 5e-12
Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK ++ FYAPWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMR 246
G+PT+ +F G P Y + IV +++
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ +V FYA WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 60.1 bits (139), Expect = 2e-08
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 181 DYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPT--LLYFERGQFRF-PYNGE 235
++ AA KG+ + ID N +I + + + P L+ E ++ P + E
Sbjct: 274 NFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEE 333
Query: 236 NKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALVVF 292
+ I EF + +P +++ E W + V + + D + ++ V F
Sbjct: 334 LTAERITEFCHRFLEGKIKPHLMSQEL-PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 392
Query: 293 YAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYF 349
YAPWCGHCK++ P ++K K + N ++A +D+T A + V +PTLK+F
Sbjct: 393 YAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTANEVEAVK--VHSFPTLKFF 446
Score = 58.0 bits (134), Expect = 9e-08
Identities = 56/252 (22%), Positives = 102/252 (40%), Gaps = 27/252 (10%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FLRDP------TGDLP--WEEDPTAVDI 140
+ + + K SE ++ C+ FL + +LP W++ P V +
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLV 373
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
+ V F +K K + FYAPWCG+CK + P + + K + +
Sbjct: 374 GKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKD 258
N + + FPTL +F R YNGE +F+ D
Sbjct: 426 DSTANEV--EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDD 483
Query: 259 VVDESWARDTDV 270
+ D A + D+
Sbjct: 484 LEDLEEAEEPDM 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 20/226 (8%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGY- 466
+IK I++F F AAE F +++ F D T +Q + + +K
Sbjct: 252 EIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEE 311
Query: 467 -PTIKYFSYFDKAVK-----DYTGGQKEGDFVS-FIHNQMGTKQTSQKAPKTTQDAGFGA 519
P ++ + ++ K + ++ +F F+ ++ SQ+ P+
Sbjct: 312 CPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKV 371
Query: 520 NVLLAFDD-DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVAL 577
V F+D F++ +V V FYA WC HC P + +L K EN+ + +
Sbjct: 372 LVGKNFEDVAFDEKKNV----FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
Query: 578 EAAENPKAADFAGIQTLPTFKLF--AAGKYVTDYDGDRSTEDLLKF 621
A E + + + PT K F +A + V DY+G+R+ + KF
Sbjct: 428 TANE----VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
>X05130-1|CAA28775.1| 508|Homo sapiens protein ( Human mRNA for
prolyl 4-hydoxylase beta subunit (EC 1.14.11.2)
(procollagen-L-proline, 2-oxoglutarate:oxygen
oxidoreductase, 4-hydroxylating). ).
Length = 508
Score = 98.3 bits (234), Expect = 7e-20
Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 33/248 (13%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
V+ L +F LA ++ V F+APWCGHCK + PE+ KAA K+K E LA VDAT
Sbjct: 26 VLVLRKSNFAEALAAHKYPPVEFHAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDAT 85
Query: 330 KEPDLASRFGVKGYPTLKYFNKGEF----KFDAGHARQEDQIISFIKDXXXXXXXXXXXX 385
+E DLA ++GV+GYPT+K+F G+ ++ AG R+ D I++++K
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAG--READDIVNWLKKRTGPAATTLP-- 141
Query: 386 XXXXXXXXVRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVA 445
D + + + + +++ F+ S K +F++AAE D +
Sbjct: 142 ------------DGAAAESLVESSEVAVIGFFKD--VESDSAK-QFLQAAEAIDD---IP 183
Query: 446 FGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI-HNQMG--TK 502
FG T + D+ + Y + + F FD+ ++ G + + + FI HNQ+ +
Sbjct: 184 FG---ITSNSDVFSKYQL-DKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE 239
Query: 503 QTSQKAPK 510
T Q APK
Sbjct: 240 FTEQTAPK 247
Score = 68.9 bits (161), Expect = 5e-11
Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 7/93 (7%)
Query: 159 SHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESI---LAAIDVAKPGNSKIRQLYNIT 215
+HK + F+APWCG+CK++ P+Y +AAG LK E LA +D + S + Q Y +
Sbjct: 40 AHKYPPVEFHAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE--ESDLAQQYGVR 97
Query: 216 GFPTLLYFERGQFRFP--YNGENKRQAIVEFMR 246
G+PT+ +F G P Y + IV +++
Sbjct: 98 GYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V G+PT+
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHGFPTL 443
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
+F + D+ V DY G + F F+ +
Sbjct: 444 GFFPASADRTVIDYNGERTLDGFKKFLES 472
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 181 DYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPT--LLYFERGQFRF-PYNGE 235
++ AA KG+ + ID N +I + + + P L+ E ++ P + E
Sbjct: 274 NFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEE 333
Query: 236 NKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAILAKAEHALVVF 292
+ I EF + +P +++ E W + V + + D + ++ V F
Sbjct: 334 LTAERITEFCHRFLEGKIKPHLMSQEL-PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 392
Query: 293 YAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYF 349
YAPWCGHCK++ P ++K K + N ++A +D+T A + V G+PTL +F
Sbjct: 393 YAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTANEVEAVK--VHGFPTLGFF 446
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/252 (22%), Positives = 103/252 (40%), Gaps = 27/252 (10%)
Query: 36 KTNVLVLFVNEMKKAHNMVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEK-P 94
KT++L+ + + FK A++ +G+ I ID +++DN+++ + + E+ P
Sbjct: 254 KTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECP 313
Query: 95 FILKHYKDGDFNKDYDRSES-----VSSMCN-FLRDP------TGDLP--WEEDPTAVDI 140
+ + + K SE ++ C+ FL + +LP W++ P V +
Sbjct: 314 AVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLV 373
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
+ V F +K K + FYAPWCG+CK + P + + K + +
Sbjct: 374 GKNFED---VAFDEK-----KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKD 258
N + + GFPTL +F R YNGE +F+ D
Sbjct: 426 DSTANEV--EAVKVHGFPTLGFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDVDD 483
Query: 259 VVDESWARDTDV 270
+ D A + D+
Sbjct: 484 LEDLEEAEEPDM 495
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 520 NVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEA 579
+VL+ +F + ++ V F+A WC HC P +++ A LK E ++ ++A
Sbjct: 25 HVLVLRKSNFAEALAAHKYPPVEFHAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 84
Query: 580 AENPKAADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKR 624
E A G++ PT K F G + +Y R +D++ + K+
Sbjct: 85 TEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
Score = 49.2 bits (112), Expect = 4e-05
Identities = 53/223 (23%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGY- 466
+IK I++F F AAE F +++ F D T +Q + + +K
Sbjct: 252 EIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEE 311
Query: 467 -PTIKYFSYFDKAVK-----DYTGGQKEGDFVS-FIHNQMGTKQTSQKAPKTTQDAGFGA 519
P ++ + ++ K + ++ +F F+ ++ SQ+ P+
Sbjct: 312 CPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKV 371
Query: 520 NVLLAFDD-DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALE 578
V F+D F++ +V V FYA WC HC P + +L K V A
Sbjct: 372 LVGKNFEDVAFDEKKNV----FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
Query: 579 AAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
A +A G TL F +A + V DY+G+R+ + KF
Sbjct: 428 TANEVEAVKVHGFPTLGFFPA-SADRTVIDYNGERTLDGFKKF 469
>Z49835-1|CAA89996.1| 505|Homo sapiens protein disulfide isomerase
protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>U75885-1|AAC51518.1| 505|Homo sapiens ER-60 protein protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>U42068-1|AAC50331.1| 505|Homo sapiens P58 protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>D16234-1|BAA03759.1| 505|Homo sapiens phospholipase C-alpha
protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 66.9 bits (156), Expect = 2e-10
Identities = 36/103 (34%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K D + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSDPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>BC071878-1|AAH71878.1| 505|Homo sapiens protein disulfide
isomerase family A, member 3 protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>BC036000-1|AAH36000.4| 505|Homo sapiens protein disulfide
isomerase family A, member 3 protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>BC014433-1|AAH14433.1| 505|Homo sapiens protein disulfide
isomerase family A, member 3 protein.
Length = 505
Score = 88.6 bits (210), Expect = 6e-17
Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 10/113 (8%)
Query: 265 ARDTDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
A +DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K G
Sbjct: 22 AAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----G 76
Query: 322 I--LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
I LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 77 IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>D83485-1|BAA11928.1| 505|Homo sapiens ER-60 protease protein.
Length = 505
Score = 88.2 bits (209), Expect = 8e-17
Identities = 48/110 (43%), Positives = 66/110 (60%), Gaps = 10/110 (9%)
Query: 268 TDVVHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGI-- 322
+DV+ L D+F++ ++ A LV F+APWCGHCKR+ PE+E AAT++K GI
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-----GIVP 79
Query: 323 LAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
LA VD T + +++GV GYPTLK F GE R D I+S +K
Sbjct: 80 LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLK 129
Score = 74.9 bits (176), Expect = 8e-13
Identities = 37/109 (33%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K ++ FYAPWCGHCK+ +P++ + E+ + + + +D T + D+ + Y V+G+PTI
Sbjct: 395 KDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRGFPTI 453
Query: 470 KYFSYFDKAV--KDYTGGQKEGDFVSFIHNQMGTKQTSQ-KAPKTTQDA 515
YFS +K + K Y GG++ DF+S++ + Q + PK + A
Sbjct: 454 -YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKA 501
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+APWCGHCK PE+ AA + +V VDCT + + C Y V GYPT+K F
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIF 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMGTK----QTSQKAPKTTQDAGFGANVLLAFDDD 528
++A Y G + VS + Q G +T ++ K D A+++ FDD
Sbjct: 107 RDGEEA-GAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDK--DASIVGFFDDS 163
Query: 529 FEK 531
F +
Sbjct: 164 FSE 166
Score = 70.1 bits (164), Expect = 2e-11
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGF 217
GS ++ F+APWCG+CK + P+Y AA LKG LA +D N+ Y ++G+
Sbjct: 43 GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT--ANTNTCNKYGVSGY 100
Query: 218 PTLLYFERGQFRFPYNGENKRQAIVEFMR---DPVAQPKQKKKDVVDESWARDTDVVHLN 274
PTL F G+ Y+G IV ++ P + P + +++ +D +V
Sbjct: 101 PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF 160
Query: 275 GDSF 278
DSF
Sbjct: 161 DDSF 164
Score = 65.3 bits (152), Expect = 6e-10
Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 6/103 (5%)
Query: 256 KKDVVDESWARDTDVVHLNGDSFDAILAKA-EHALVVFYAPWCGHCKRIKPEFEKAATKI 314
K + + ES D V + ++FD I+ + L+ FYAPWCGHCK ++P++++ K+
Sbjct: 366 KSEPIPES--NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKL 423
Query: 315 KTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKGEFKFD 357
+ N ++A +DAT D+ S + V+G+PT+ YF+ K +
Sbjct: 424 SKDP-NIVIAKMDATAN-DVPSPYEVRGFPTI-YFSPANKKLN 463
Score = 58.8 bits (136), Expect = 5e-08
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Query: 519 ANVLLAFDDDFEKIISVPTPT---IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
++VL DD+FE IS +V F+A WC HC P + AT LK VP+ V
Sbjct: 25 SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-GIVPLAKV 83
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ N + G+ PT K+F G+ YDG R+ + ++ K+ A
Sbjct: 84 --DCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQA 132
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 160 HKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPT 219
+K +I FYAPWCG+CK+++P Y E L + + + N + Y + GFPT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND-VPSPYEVRGFPT 452
Query: 220 LLYFERGQFRFP--YNGENKRQAIVEFMR-----DPVAQ---PKQKKK 257
+ + + P Y G + + +++ PV Q PK+KKK
Sbjct: 453 IYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 527 DDFEKIISVPTPTIVM-FYATWCSHCVTAKPAFSRLATAL-KTENVPVKAVALEAAENPK 584
++F++I++ +++ FYA WC HC +P + L L K N+ + + A + P
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPS 443
Query: 585 AADFAGIQTLPTFKLFAAGKYVT--DYDGDRSTEDLLKFCKRHA 626
+ G PT A K + Y+G R D + + +R A
Sbjct: 444 PYEVRG---FPTIYFSPANKKLNPKKYEGGRELSDFISYLQREA 484
>AK074905-1|BAC11281.1| 277|Homo sapiens protein ( Homo sapiens
cDNA FLJ90424 fis, clone NT2RP3000436, highly similar to
ER-resident protein ERdj5. ).
Length = 277
Score = 87.4 bits (207), Expect = 1e-16
Identities = 66/276 (23%), Positives = 122/276 (44%), Gaps = 38/276 (13%)
Query: 211 LYNITGFPTLLYFERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV 270
+YNI +PT + F + Y G + + I+EF+ D + + V
Sbjct: 1 MYNIQAYPTTVVFNQSNIH-EYEGHHSAEQILEFIEDLM-----------------NPSV 42
Query: 271 VHLNGDSFDAILAKAEHA---LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVD 327
V L +F+ ++ + +H +V FY+PWC C+ + PE+++ A + T IN + ++D
Sbjct: 43 VSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLIN--VGSID 99
Query: 328 ATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXX 387
+ ++ V+ YP +++F K H+ + +D
Sbjct: 100 CQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYN-----GWNRDAYSLRIWGLGFLPQ 154
Query: 388 XXXXXXVRHLDSSTF-RNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAF 446
L TF L+ H ++ FYAPWCG C++ PEF A + V
Sbjct: 155 VSTD-----LTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKA 207
Query: 447 GAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
G VDC + C ++ YPT+K++ ++++A +++
Sbjct: 208 GKVDCQAYAQTCQKAGIRAYPTVKFY-FYERAKRNF 242
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/268 (26%), Positives = 109/268 (40%), Gaps = 41/268 (15%)
Query: 338 FGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIKDXXXXXXXXXXXXXXXXXXXXVRHL 397
+ ++ YPT FN+ GH E QI+ FI+D V L
Sbjct: 2 YNIQAYPTTVVFNQSNIHEYEGHHSAE-QILEFIEDLMNPS---------------VVSL 45
Query: 398 DSSTFRNTLRKIKHS---IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLH 454
+TF + + KH+ +V FY+PWC C+ PE+ + A ++ G++DC +
Sbjct: 46 TPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG--LINVGSIDCQQY 103
Query: 455 QDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTKQTSQKAPKTTQD 514
CA NV+ YP I++F K+ K Y H+ G + +
Sbjct: 104 HSFCAQENVQRYPEIRFFP--PKSNKAY-----------HYHSYNGWNRDAYSL--RIWG 148
Query: 515 AGFGANVL--LAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPV 572
GF V L EK++ ++ FYA WC C P F LA +K + V
Sbjct: 149 LGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK---V 205
Query: 573 KAVALEAAENPKAADFAGIQTLPTFKLF 600
KA ++ + AGI+ PT K +
Sbjct: 206 KAGKVDCQAYAQTCQKAGIRAYPTVKFY 233
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 24/190 (12%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
M+ FY+PWC C+ + P++ A L G + +ID + + ++ N+ +P + +F
Sbjct: 64 MVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQE--NVQRYPEIRFF 121
Query: 224 ----ERGQFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDVVHLNGDSFD 279
+ YNG N+ + + Q D+ ++++ +
Sbjct: 122 PPKSNKAYHYHSYNGWNRDAYSLRIW--GLGFLPQVSTDLTPQTFS-------------E 166
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
+L H ++ FYAPWCG C+ PEFE A IK + G VD + G
Sbjct: 167 KVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAG---KVDCQAYAQTCQKAG 223
Query: 340 VKGYPTLKYF 349
++ YPT+K++
Sbjct: 224 IRAYPTVKFY 233
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL--L 221
+I FYAPWCG C++ P++ A +KG+ +D ++ Q I +PT+
Sbjct: 176 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDC--QAYAQTCQKAGIRAYPTVKFY 233
Query: 222 YFERGQFRFPYNGENKRQA 240
++ER + F N R A
Sbjct: 234 FYERAKRNFQEEQINTRDA 252
>Z69667-10|CAI95587.1| 226|Homo sapiens protein disulfide isomerase
family A, member 2 protein.
Length = 226
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 50 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 109
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 110 VTEYPTLKFFRNG 122
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 23 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 77
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 78 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 137
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 138 GIAEWLRRRVGPSAMRLED 156
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 43 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 102
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 103 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 148
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 59 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 118
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 119 FRNGNRTHPEEYTGPRDAEGIAEWLRR 145
>Z69667-9|CAI95586.1| 525|Homo sapiens protein disulfide isomerase
family A, member 2 protein.
Length = 525
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 54 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 113
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 114 VTEYPTLKFFRNG 126
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 27 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 81
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 82 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 141
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 142 GIAEWLRRRVGPSAMRLED 160
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 47 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 106
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 107 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 299 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 357
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 358 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 416
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 417 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 470
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRR 149
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 407 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 464
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 465 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 493
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 277 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 335
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 336 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 392
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 393 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 446
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 447 DATANE--LDAFAVHGFPTLKYFPAGPGR 473
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 397 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 453
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 454 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 490
>U19948-1|AAC50401.1| 511|Homo sapiens protein disulfide isomerase
protein.
Length = 511
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 40 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 99
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 100 VTEYPTLKFFRNG 112
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 13 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 67
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 68 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 127
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 128 GIAEWLRRRVGPSAMRLED 146
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 33 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 92
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 93 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 138
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 285 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 343
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 344 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 402
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 403 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 456
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 49 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 108
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 109 FRNGNRTHPEEYTGPRDAEGIAEWLRR 135
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 393 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 450
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 451 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 479
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 263 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 321
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 322 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 378
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 379 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 432
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 433 DATANE--LDAFAVHGFPTLKYFPAGPGR 459
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 383 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 439
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 440 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 476
>EF450770-1|ABO43034.1| 555|Homo sapiens protein disulfide
isomerase family A, member 2 variant protein.
Length = 555
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 54 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 113
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 114 VTEYPTLKFFRNG 126
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 27 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 81
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 82 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 141
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 142 GIAEWLRRRVGPSAMRLED 160
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 47 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 106
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 107 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 299 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 357
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 358 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 416
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 417 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 470
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRR 149
Score = 55.2 bits (127), Expect = 7e-07
Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 407 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 464
Query: 470 KYF 472
KYF
Sbjct: 465 KYF 467
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 277 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 335
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 336 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 392
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 393 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 446
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 447 DATANE--LDAFAVHGFPTLKYFPAGPGR 473
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 397 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 453
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 454 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 490
>BC075029-1|AAH75029.1| 519|Homo sapiens PDIA2 protein protein.
Length = 519
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 48 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 107
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 108 VTEYPTLKFFRNG 120
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 21 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 75
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 76 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 135
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 136 GIAEWLRRRVGPSAMRLED 154
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 41 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 100
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 101 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 146
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 293 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 351
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 352 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 410
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 411 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 464
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 57 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 116
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 117 FRNGNRTHPEEYTGPRDAEGIAEWLRR 143
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 401 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 458
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 459 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 487
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 271 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 329
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 330 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 386
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 387 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 440
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 441 DATANE--LDAFAVHGFPTLKYFPAGPGR 467
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 391 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 447
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 448 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 484
>BC000537-1|AAH00537.2| 520|Homo sapiens PDIA2 protein protein.
Length = 520
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 49 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 108
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 109 VTEYPTLKFFRNG 121
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 22 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 76
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 77 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 136
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 137 GIAEWLRRRVGPSAMRLED 155
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 42 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 101
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 102 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 147
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 294 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 352
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 353 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 411
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 412 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 465
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 58 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 117
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 118 FRNGNRTHPEEYTGPRDAEGIAEWLRR 144
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 402 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 459
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 460 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 488
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 272 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 330
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 331 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 387
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 388 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 441
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 442 DATANE--LDAFAVHGFPTLKYFPAGPGR 468
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 392 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 448
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 449 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 485
>AE006463-3|AAK61223.1| 525|Homo sapiens protein disulfide
isomerase PDIP precursor protein.
Length = 525
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 54 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 113
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 114 VTEYPTLKFFRNG 126
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 27 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 81
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 82 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 141
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 142 GIAEWLRRRVGPSAMRLED 160
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 47 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 106
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 107 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 299 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 357
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 358 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 416
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 417 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 470
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRR 149
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 407 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 464
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 465 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 493
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 277 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 335
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 336 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 392
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 393 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 446
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 447 DATANE--LDAFAVHGFPTLKYFPAGPGR 473
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 397 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 453
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 454 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 490
>AB127078-2|BAE48734.1| 525|Homo sapiens pancreatic protein
disulfide isomerase protein.
Length = 525
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 45/73 (61%), Gaps = 2/73 (2%)
Query: 282 LAKAEHA--LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFG 339
LA EH LV FYAPWCGHC+ + PE+ KAA + E + LA VD + +LA FG
Sbjct: 54 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 113
Query: 340 VKGYPTLKYFNKG 352
V YPTLK+F G
Sbjct: 114 VTEYPTLKFFRNG 126
Score = 71.3 bits (167), Expect = 9e-12
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 123 RDPTGDLPWEEDPTAVDIYHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDY 182
R P+ + P EE P I +L + L++ H ++ FYAPWCG+C+++ P+Y
Sbjct: 27 RSPSEEPPEEEIPKEDGIL-VLSRHTLGLALRE----HPALLVEFYAPWCGHCQALAPEY 81
Query: 183 VEAAGDLKGESILAAI-DVAKPGNSKIRQLYNITGFPTLLYFERGQFRFP--YNGENKRQ 239
+AA L ES++ + V P ++ + + +T +PTL +F G P Y G +
Sbjct: 82 SKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAE 141
Query: 240 AIVEFMRDPVAQPKQKKKD 258
I E++R V + +D
Sbjct: 142 GIAEWLRRRVGPSAMRLED 160
Score = 68.5 bits (160), Expect = 7e-11
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADE-LMVAFGAVDCTLHQ 455
L T LR+ +V FYAPWCGHC++ PE+ KAA A E ++V VD +
Sbjct: 47 LSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQR 106
Query: 456 DLCANYNVKGYPTIKYFSYFDKA-VKDYTGGQKEGDFVSFIHNQMG 500
+L + V YPT+K+F ++ ++YTG + ++ ++G
Sbjct: 107 ELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 13/177 (7%)
Query: 184 EAAGDLKGESILAAIDVAKPGNSKIRQLYNITG--FPTL--LYFERGQFRFPYNGENKRQ 239
EAA +G+ + +DVA N + Q + + PTL + E + P +G
Sbjct: 299 EAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTA 357
Query: 240 AIVEFMRDPVAQPKQKKKDVVDESWARDTD---VVHLNGDSFDAI-LAKAEHALVVFYAP 295
A + V Q K ++ + D D V L G +F+ + + ++ V FYAP
Sbjct: 358 ASITAFCHAVLNG-QVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAP 416
Query: 296 WCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
WC HCK + P +E A K + + + I+A +DAT F V G+PTLKYF G
Sbjct: 417 WCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATANE--LDAFAVHGFPTLKYFPAG 470
Score = 56.0 bits (129), Expect = 4e-07
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC P +S+ A L E++ V ++ + A+ G+ PT K
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 600 FAAGK--YVTDYDGDRSTEDLLKFCKR 624
F G + +Y G R E + ++ +R
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRR 149
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 407 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 464
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 465 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 493
Score = 48.8 bits (111), Expect = 6e-05
Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 38 NVLVLFVNEMKKAHN-MVEVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSPEKPFI 96
N L+LFVN+ AH ++ F E A RGQ +++D +DN+ + + + E
Sbjct: 277 NHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPT 335
Query: 97 LKHYKDGDFNKDYD-------RSESVSSMCNFLRDP-------TGDLP--WEEDPTAVDI 140
L+ + + K Y + S+++ C+ + + + ++P W++ P
Sbjct: 336 LR-LVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKT-- 392
Query: 141 YHLLDGEAIVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDV 200
L G+ F + K + FYAPWC +CK M P + A + + ++
Sbjct: 393 ---LVGK---NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAEL 446
Query: 201 AKPGNSKIRQLYNITGFPTLLYFERGQFR 229
N + + GFPTL YF G R
Sbjct: 447 DATANE--LDAFAVHGFPTLKYFPAGPGR 473
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 397 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 453
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 454 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 490
>BC107422-1|AAI07423.1| 423|Homo sapiens Unknown (protein for
IMAGE:4693508) protein.
Length = 423
Score = 74.5 bits (175), Expect = 1e-12
Identities = 34/82 (41%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV FYAPWCGHCK+++P + + ++K+ + +DAT +AS FGV+GYPT+K
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 349 FNKGEFKFDAGHARQEDQIISF 370
KG+ ++ R +D II F
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEF 125
Score = 61.7 bits (143), Expect = 8e-09
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAA-EQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+V FYAPWCGHCK +P + + E + V G +D T + + + + V+GYPTIK
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
+Y G + + D + F H G
Sbjct: 105 LK--GDLAYNYRGPRTKDDIIEFAHRVSG 131
Score = 58.4 bits (135), Expect = 7e-08
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC +P ++ + +K+ PVK ++A A G++ PT KL
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 600 FAAGKYVTDYDGDRSTEDLLKFCKR 624
G +Y G R+ +D+++F R
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEFAHR 128
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK ++P + E ++K SI + + V K S I + + G+PT+
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMK--SIGSPVKVGKMDATSYSSIASEFGVRGYPTI 102
Query: 221 LYFERGQFRFPYNGENKRQAIVEF 244
+G + Y G + I+EF
Sbjct: 103 KLL-KGDLAYNYRGPRTKDDIIEF 125
>BC093794-1|AAH93794.1| 454|Homo sapiens thioredoxin domain
containing 10 protein.
Length = 454
Score = 74.5 bits (175), Expect = 1e-12
Identities = 34/82 (41%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV FYAPWCGHCK+++P + + ++K+ + +DAT +AS FGV+GYPT+K
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 349 FNKGEFKFDAGHARQEDQIISF 370
KG+ ++ R +D II F
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEF 125
Score = 61.7 bits (143), Expect = 8e-09
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAA-EQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+V FYAPWCGHCK +P + + E + V G +D T + + + + V+GYPTIK
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
+Y G + + D + F H G
Sbjct: 105 LK--GDLAYNYRGPRTKDDIIEFAHRVSG 131
Score = 58.4 bits (135), Expect = 7e-08
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC +P ++ + +K+ PVK ++A A G++ PT KL
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 600 FAAGKYVTDYDGDRSTEDLLKFCKR 624
G +Y G R+ +D+++F R
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEFAHR 128
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK ++P + E ++K SI + + V K S I + + G+PT+
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMK--SIGSPVKVGKMDATSYSSIASEFGVRGYPTI 102
Query: 221 LYFERGQFRFPYNGENKRQAIVEF 244
+G + Y G + I+EF
Sbjct: 103 KLL-KGDLAYNYRGPRTKDDIIEF 125
>BC093792-1|AAH93792.1| 454|Homo sapiens thioredoxin domain
containing 10 protein.
Length = 454
Score = 74.5 bits (175), Expect = 1e-12
Identities = 34/82 (41%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV FYAPWCGHCK+++P + + ++K+ + +DAT +AS FGV+GYPT+K
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 349 FNKGEFKFDAGHARQEDQIISF 370
KG+ ++ R +D II F
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEF 125
Score = 61.7 bits (143), Expect = 8e-09
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAA-EQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+V FYAPWCGHCK +P + + E + V G +D T + + + + V+GYPTIK
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
+Y G + + D + F H G
Sbjct: 105 LK--GDLAYNYRGPRTKDDIIEFAHRVSG 131
Score = 58.4 bits (135), Expect = 7e-08
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC +P ++ + +K+ PVK ++A A G++ PT KL
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 600 FAAGKYVTDYDGDRSTEDLLKFCKR 624
G +Y G R+ +D+++F R
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEFAHR 128
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK ++P + E ++K SI + + V K S I + + G+PT+
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMK--SIGSPVKVGKMDATSYSSIASEFGVRGYPTI 102
Query: 221 LYFERGQFRFPYNGENKRQAIVEF 244
+G + Y G + I+EF
Sbjct: 103 KLL-KGDLAYNYRGPRTKDDIIEF 125
>AB058733-1|BAB47459.1| 486|Homo sapiens KIAA1830 protein protein.
Length = 486
Score = 74.5 bits (175), Expect = 1e-12
Identities = 34/82 (41%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV FYAPWCGHCK+++P + + ++K+ + +DAT +AS FGV+GYPT+K
Sbjct: 77 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 136
Query: 349 FNKGEFKFDAGHARQEDQIISF 370
KG+ ++ R +D II F
Sbjct: 137 L-KGDLAYNYRGPRTKDDIIEF 157
Score = 61.7 bits (143), Expect = 8e-09
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAA-EQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+V FYAPWCGHCK +P + + E + V G +D T + + + + V+GYPTIK
Sbjct: 77 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 136
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
+Y G + + D + F H G
Sbjct: 137 LK--GDLAYNYRGPRTKDDIIEFAHRVSG 163
Score = 58.4 bits (135), Expect = 7e-08
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC +P ++ + +K+ PVK ++A A G++ PT KL
Sbjct: 77 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 136
Query: 600 FAAGKYVTDYDGDRSTEDLLKFCKR 624
G +Y G R+ +D+++F R
Sbjct: 137 L-KGDLAYNYRGPRTKDDIIEFAHR 160
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK ++P + E ++K SI + + V K S I + + G+PT+
Sbjct: 77 LVDFYAPWCGHCKKLEPIWNEVGLEMK--SIGSPVKVGKMDATSYSSIASEFGVRGYPTI 134
Query: 221 LYFERGQFRFPYNGENKRQAIVEF 244
+G + Y G + I+EF
Sbjct: 135 KLL-KGDLAYNYRGPRTKDDIIEF 157
>BC032325-1|AAH32325.1| 195|Homo sapiens TXNDC10 protein protein.
Length = 195
Score = 71.3 bits (167), Expect = 9e-12
Identities = 33/82 (40%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
LV FYAPWCGHCK+++ + + ++K+ + +DAT +AS FGV+GYPT+K
Sbjct: 45 LVDFYAPWCGHCKKLESIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 349 FNKGEFKFDAGHARQEDQIISF 370
KG+ ++ R +D II F
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEF 125
Score = 58.4 bits (135), Expect = 7e-08
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAA-EQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
+V FYAPWCGHCK + + + E + V G +D T + + + + V+GYPTIK
Sbjct: 45 LVDFYAPWCGHCKKLESIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 472 FSYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
+Y G + + D + F H G
Sbjct: 105 LK--GDLAYNYRGPRTKDDIIEFAHRVSG 131
Score = 55.2 bits (127), Expect = 7e-07
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V FYA WC HC + ++ + +K+ PVK ++A A G++ PT KL
Sbjct: 45 LVDFYAPWCGHCKKLESIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 600 FAAGKYVTDYDGDRSTEDLLKFCKR 624
G +Y G R+ +D+++F R
Sbjct: 105 L-KGDLAYNYRGPRTKDDIIEFAHR 128
Score = 50.4 bits (115), Expect = 2e-05
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAK---PGNSKIRQLYNITGFPTL 220
++ FYAPWCG+CK ++ + E ++K SI + + V K S I + + G+PT+
Sbjct: 45 LVDFYAPWCGHCKKLESIWNEVGLEMK--SIGSPVKVGKMDATSYSSIASEFGVRGYPTI 102
Query: 221 LYFERGQFRFPYNGENKRQAIVEF 244
+G + Y G + I+EF
Sbjct: 103 KLL-KGDLAYNYRGPRTKDDIIEF 125
>BC005374-1|AAH05374.1| 406|Homo sapiens thioredoxin domain
containing 4 (endoplasmic reticulum) protein.
Length = 406
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>AL360084-2|CAH70308.1| 406|Homo sapiens thioredoxin domain
containing 4 (endoplasmic reticulum) protein.
Length = 406
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>AL358937-2|CAI95319.1| 406|Homo sapiens thioredoxin domain
containing 4 (endoplasmic reticulum) protein.
Length = 406
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>AL137072-1|CAH72172.1| 406|Homo sapiens thioredoxin domain
containing 4 (endoplasmic reticulum) protein.
Length = 406
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>AJ344330-1|CAC87611.1| 406|Homo sapiens ERp44 protein protein.
Length = 406
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>AB011145-1|BAA25499.1| 451|Homo sapiens KIAA0573 protein protein.
Length = 451
Score = 67.7 bits (158), Expect = 1e-10
Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L+ ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 74 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 133
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 134 RVDCDQHSDIAQRYRISKYPTLKLFRNG 161
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAV 449
+ LD+ L ++V FYA WC + P F +A+ E+F +E V F V
Sbjct: 76 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 135
Query: 450 DCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
DC H D+ Y + YPT+K F ++Y G + +I Q
Sbjct: 136 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 184
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 94 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 151
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 152 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 197
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 82 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 141
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 142 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 183
>AY359048-1|AAQ89407.1| 406|Homo sapiens TXNDC4 protein.
Length = 406
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Query: 268 TDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING---ILA 324
T++ L ++ D IL A+ ALV FYA WC + + P FE+A+ IK E N + A
Sbjct: 29 TEITSLATENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKG 352
VD + D+A R+ + YPTLK F G
Sbjct: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
Score = 58.0 bits (134), Expect = 9e-08
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAA----EQFADELMVAFGAVDCTLHQDLCANYNVKGYP 467
++V FYA WC + P F +A+ E+F +E V F VDC H D+ Y + YP
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYP 108
Query: 468 TIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQ 498
T+K F ++Y G + +I Q
Sbjct: 109 TLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
Score = 52.4 bits (120), Expect = 5e-06
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGE------SILAAIDVAKPGNSKIRQLYNITG 216
+++ FYA WC + + + P + EA+ +K E + A +D + +S I Q Y I+
Sbjct: 49 ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQ--HSDIAQRYRISK 106
Query: 217 FPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPVAQPKQKKKDVVD 261
+PTL F G + Y G+ +A+ +++R + P Q+ +D+ +
Sbjct: 107 YPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Score = 40.3 bits (90), Expect = 0.020
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
++ ++I++ +V FYA WC P F + +K E V + + +
Sbjct: 37 ENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHS 96
Query: 587 DFA---GIQTLPTFKLFAAGKYV-TDYDGDRSTEDLLKFCKR 624
D A I PT KLF G + +Y G RS + L + ++
Sbjct: 97 DIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
>BC036460-1|AAH36460.1| 280|Homo sapiens thioredoxin domain
containing 1 protein.
Length = 280
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C+ ++PE+E A + ++N +A VD T++P L+ RF + PT+ +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVN--IAKVDVTEQPGLSGRFIINALPTIYH 105
Query: 349 FNKGEFKFDAGHARQEDQIISFIKD 373
GEF+ G ++D I+FI D
Sbjct: 106 CKDGEFRRYQGPRTKKD-FINFISD 129
Score = 52.8 bits (121), Expect = 4e-06
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C++ +PE+ AE + ++L V VD T L + + PTI +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVTEQPGLSGRFIINALPTIYHC 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQ 498
D + Y G + + DF++FI ++
Sbjct: 107 K--DGEFRRYQGPRTKKDFINFISDK 130
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 10/88 (11%)
Query: 164 MIMFYAPWCGYCKSMKPD---YVEAAGDLKGESILAAIDVA-KPGNSKIRQLYNITGFPT 219
MI FYAPWC C++++P+ + E DL E +A +DV +PG + + I PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL--EVNIAKVDVTEQPG---LSGRFIINALPT 102
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRD 247
+ + + G+FR Y G ++ + F+ D
Sbjct: 103 IYHCKDGEFR-RYQGPRTKKDFINFISD 129
Score = 39.1 bits (87), Expect = 0.047
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
G +NV + D+++ +++ ++ FYA WC C +P + A E++ V
Sbjct: 26 GRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIA 81
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++ E P + I LPT G++ Y G R+ +D + F
Sbjct: 82 KVDVTEQPGLSGRFIINALPTIYHCKDGEF-RRYQGPRTKKDFINF 126
>BC056874-1|AAH56874.2| 280|Homo sapiens thioredoxin domain
containing 1 protein.
Length = 280
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C+ ++PE+E A + ++N +A VD T++P L+ RF + PT+ +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVN--IAKVDVTEQPGLSGRFIITALPTIYH 105
Query: 349 FNKGEFKFDAGHARQEDQIISFIKD 373
GEF+ G ++D I+FI D
Sbjct: 106 CKDGEFRRYQGPRTKKD-FINFISD 129
Score = 52.4 bits (120), Expect = 5e-06
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C++ +PE+ AE + ++L V VD T L + + PTI +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQ 498
D + Y G + + DF++FI ++
Sbjct: 107 K--DGEFRRYQGPRTKKDFINFISDK 130
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 10/88 (11%)
Query: 164 MIMFYAPWCGYCKSMKPD---YVEAAGDLKGESILAAIDVA-KPGNSKIRQLYNITGFPT 219
MI FYAPWC C++++P+ + E DL E +A +DV +PG + + IT PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL--EVNIAKVDVTEQPG---LSGRFIITALPT 102
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRD 247
+ + + G+FR Y G ++ + F+ D
Sbjct: 103 IYHCKDGEFR-RYQGPRTKKDFINFISD 129
Score = 38.7 bits (86), Expect = 0.062
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
G +NV + D+++ +++ ++ FYA WC C +P + A E++ V
Sbjct: 26 GRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIA 81
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++ E P + I LPT G++ Y G R+ +D + F
Sbjct: 82 KVDVTEQPGLSGRFIITALPTIYHCKDGEF-RRYQGPRTKKDFINF 126
>AY358640-1|AAQ89003.1| 280|Homo sapiens TXNDC protein.
Length = 280
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C+ ++PE+E A + ++N +A VD T++P L+ RF + PT+ +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVN--IAKVDVTEQPGLSGRFIITALPTIYH 105
Query: 349 FNKGEFKFDAGHARQEDQIISFIKD 373
GEF+ G ++D I+FI D
Sbjct: 106 CKDGEFRRYQGPRTKKD-FINFISD 129
Score = 52.4 bits (120), Expect = 5e-06
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C++ +PE+ AE + ++L V VD T L + + PTI +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQ 498
D + Y G + + DF++FI ++
Sbjct: 107 K--DGEFRRYQGPRTKKDFINFISDK 130
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 10/88 (11%)
Query: 164 MIMFYAPWCGYCKSMKPD---YVEAAGDLKGESILAAIDVA-KPGNSKIRQLYNITGFPT 219
MI FYAPWC C++++P+ + E DL E +A +DV +PG + + IT PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL--EVNIAKVDVTEQPG---LSGRFIITALPT 102
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRD 247
+ + + G+FR Y G ++ + F+ D
Sbjct: 103 IYHCKDGEFR-RYQGPRTKKDFINFISD 129
Score = 38.7 bits (86), Expect = 0.062
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
G +NV + D+++ +++ ++ FYA WC C +P + A E++ V
Sbjct: 26 GRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIA 81
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++ E P + I LPT G++ Y G R+ +D + F
Sbjct: 82 KVDVTEQPGLSGRFIITALPTIYHCKDGEF-RRYQGPRTKKDFINF 126
>AK075395-1|BAC11593.1| 280|Homo sapiens protein ( Homo sapiens
cDNA PSEC0085 fis, clone NT2RP2006476, highly similar to
Thioredoxin domain containing protein. ).
Length = 280
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C+ ++PE+E A + ++N +A VD T++P L+ RF + PT+ +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVN--IAKVDVTEQPGLSGRFIITALPTIYH 105
Query: 349 FNKGEFKFDAGHARQEDQIISFIKD 373
GEF+ G ++D I+FI D
Sbjct: 106 CKDGEFRRYQGPRTKKD-FINFISD 129
Score = 52.4 bits (120), Expect = 5e-06
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C++ +PE+ AE + ++L V VD T L + + PTI +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQ 498
D + Y G + + DF++FI ++
Sbjct: 107 K--DGEFRRYQGPRTKKDFINFISDK 130
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 10/88 (11%)
Query: 164 MIMFYAPWCGYCKSMKPD---YVEAAGDLKGESILAAIDVA-KPGNSKIRQLYNITGFPT 219
MI FYAPWC C++++P+ + E DL E +A +DV +PG + + IT PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL--EVNIAKVDVTEQPG---LSGRFIITALPT 102
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRD 247
+ + + G+FR Y G ++ + F+ D
Sbjct: 103 IYHCKDGEFR-RYQGPRTKKDFINFISD 129
Score = 38.7 bits (86), Expect = 0.062
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
G +NV + D+++ +++ ++ FYA WC C +P + A E++ V
Sbjct: 26 GRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIA 81
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++ E P + I LPT G++ Y G R+ +D + F
Sbjct: 82 KVDVTEQPGLSGRFIITALPTIYHCKDGEF-RRYQGPRTKKDFINF 126
>AB048246-1|BAB20629.1| 280|Homo sapiens thioredoxin-related
transmembrane protein protein.
Length = 280
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C+ ++PE+E A + ++N +A VD T++P L+ RF + PT+ +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVN--IAKVDVTEQPGLSGRFIITALPTIYH 105
Query: 349 FNKGEFKFDAGHARQEDQIISFIKD 373
GEF+ G ++D I+FI D
Sbjct: 106 CKDGEFRRYQGPRTKKD-FINFISD 129
Score = 52.4 bits (120), Expect = 5e-06
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C++ +PE+ AE + ++L V VD T L + + PTI +
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQ 498
D + Y G + + DF++FI ++
Sbjct: 107 K--DGEFRRYQGPRTKKDFINFISDK 130
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 10/88 (11%)
Query: 164 MIMFYAPWCGYCKSMKPD---YVEAAGDLKGESILAAIDVA-KPGNSKIRQLYNITGFPT 219
MI FYAPWC C++++P+ + E DL E +A +DV +PG + + IT PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL--EVNIAKVDVTEQPG---LSGRFIITALPT 102
Query: 220 LLYFERGQFRFPYNGENKRQAIVEFMRD 247
+ + + G+FR Y G ++ + F+ D
Sbjct: 103 IYHCKDGEFR-RYQGPRTKKDFINFISD 129
Score = 38.7 bits (86), Expect = 0.062
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 516 GFGANVLLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAV 575
G +NV + D+++ +++ ++ FYA WC C +P + A E++ V
Sbjct: 26 GRRSNVRVITDENWRELLE--GDWMIEFYAPWCPACQNLQPEWESFAE--WGEDLEVNIA 81
Query: 576 ALEAAENPKAADFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKF 621
++ E P + I LPT G++ Y G R+ +D + F
Sbjct: 82 KVDVTEQPGLSGRFIITALPTIYHCKDGEF-RRYQGPRTKKDFINF 126
>Z69667-11|CAI95588.1| 154|Homo sapiens protein disulfide isomerase
family A, member 2 protein.
Length = 154
Score = 60.5 bits (140), Expect = 2e-08
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 273 LNGDSFDAI-LAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKE 331
L G +F+ + + ++ V FYAPWC HCK + P +E A K + + + I+A +DAT
Sbjct: 22 LVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHE-DIIIAELDATAN 80
Query: 332 PDLASRFGVKGYPTLKYFNKG 352
F V G+PTLKYF G
Sbjct: 81 E--LDAFAVHGFPTLKYFPAG 99
Score = 55.6 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWC HCK P + AE++ D + +D T + +L A + V G+PT+
Sbjct: 36 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATAN-ELDA-FAVHGFPTL 93
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
KYF + + V +Y + F F+ N
Sbjct: 94 KYFPAGPGRKVIEYKSTRDLETFSKFLDN 122
Score = 48.0 bits (109), Expect = 1e-04
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 DFEKIISVPTPTI-VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
+FE++ T + V FYA WC+HC PA+ LA + ++ + L+A N
Sbjct: 26 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQ-DHEDIIIAELDATAN--EL 82
Query: 587 DFAGIQTLPTFKLFAA--GKYVTDYDGDRSTEDLLKF 621
D + PT K F A G+ V +Y R E KF
Sbjct: 83 DAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 119
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K + FYAPWC +CK M P + A + + ++ N + + GFPTL
Sbjct: 36 KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANE--LDAFAVHGFPTL 93
Query: 221 LYFERGQFR 229
YF G R
Sbjct: 94 KYFPAGPGR 102
>X07077-1|CAA30112.1| 216|Homo sapiens glutathione-insulin
transhydrogenase (216 AA) protein.
Length = 216
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 94 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 151
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 152 KFFPASADRTVIDYNGQRTLDGFKKFLES 180
Score = 56.8 bits (131), Expect = 2e-07
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 262 ESWARDTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
E W + V + + D + ++ V FYAPWCGHCK++ P ++K K + N
Sbjct: 70 EDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NI 128
Query: 322 ILAAVDATKEPDLASRFGVKGYPTLKYF 349
++A +D+T A + V +PTLK+F
Sbjct: 129 VIAKMDSTANEVEAVK--VHSFPTLKFF 154
Score = 47.2 bits (107), Expect = 2e-04
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
V FYA WC HC P + +L K EN+ + + A E + + + PT K
Sbjct: 98 VEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE----VEAVKVHSFPTLKF 153
Query: 600 F--AAGKYVTDYDGDRSTEDLLKF 621
F +A + V DY+G R+ + KF
Sbjct: 154 FPASADRTVIDYNGQRTLDGFKKF 177
Score = 45.2 bits (102), Expect = 7e-04
Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 4/112 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K + FYAPWCG+CK + P + + K + + N + + FPTL
Sbjct: 94 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEV--EAVKVHSFPTL 151
Query: 221 LYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV 270
+F R YNG+ +F+ D+ D A + D+
Sbjct: 152 KFFPASADRTVIDYNGQRTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDM 203
>BC014504-1|AAH14504.1| 185|Homo sapiens P4HB protein protein.
Length = 185
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 410 KHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTI 469
K+ V FYAPWCGHCK P + K E + D + +D T ++ V +PT+
Sbjct: 63 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 120
Query: 470 KYF-SYFDKAVKDYTGGQKEGDFVSFIHN 497
K+F + D+ V DY G + F F+ +
Sbjct: 121 KFFPASADRTVIDYNGERTLDGFKKFLES 149
Score = 56.8 bits (131), Expect = 2e-07
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 262 ESWARDTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKING 321
E W + V + + D + ++ V FYAPWCGHCK++ P ++K K + N
Sbjct: 39 EDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NI 97
Query: 322 ILAAVDATKEPDLASRFGVKGYPTLKYF 349
++A +D+T A + V +PTLK+F
Sbjct: 98 VIAKMDSTANEVEAVK--VHSFPTLKFF 123
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKT-ENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
V FYA WC HC P + +L K EN+ + + A E + + + PT K
Sbjct: 67 VEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE----VEAVKVHSFPTLKF 122
Query: 600 F--AAGKYVTDYDGDRSTEDLLKF 621
F +A + V DY+G+R+ + KF
Sbjct: 123 FPASADRTVIDYNGERTLDGFKKF 146
Score = 46.4 bits (105), Expect = 3e-04
Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 4/112 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K + FYAPWCG+CK + P + + K + + N + + FPTL
Sbjct: 63 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEV--EAVKVHSFPTL 120
Query: 221 LYFERGQFR--FPYNGENKRQAIVEFMRDPVAQPKQKKKDVVDESWARDTDV 270
+F R YNGE +F+ D+ D A + D+
Sbjct: 121 KFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDM 172
>U97276-1|AAC09010.2| 747|Homo sapiens quiescin protein.
Length = 747
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>BC100023-1|AAI00024.1| 747|Homo sapiens quiescin Q6 protein.
Length = 747
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>BC017692-1|AAH17692.1| 604|Homo sapiens quiescin Q6 protein.
Length = 604
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>AY358941-1|AAQ89300.1| 747|Homo sapiens QSCN6 protein.
Length = 747
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>AL390718-7|CAI14839.1| 604|Homo sapiens quiescin Q6 protein.
Length = 604
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>AL390718-6|CAI14838.1| 747|Homo sapiens quiescin Q6 protein.
Length = 747
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>AJ318051-1|CAC85331.1| 698|Homo sapiens putative sulfhydryl
oxidase precursor protein.
Length = 698
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 397 LDSSTFRN-TLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDC--T 452
LDS + R T +V FY+ WCGHC + P + A D + A+DC
Sbjct: 66 LDSGSVRGATANSSAAWLVQFYSSWCGHCIAYAPTWRALAGDVRDWASAIRVAALDCMEE 125
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQ 486
+Q +C +Y++ YPT +YF F K++T G+
Sbjct: 126 KNQAVCHDYDIHFYPTFRYFKAF---TKEFTTGE 156
Score = 46.4 bits (105), Expect = 3e-04
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLK--GESI-LAAIDVAKPGNSKIRQLYNITGFPTL 220
++ FY+ WCG+C + P + AGD++ +I +AA+D + N + Y+I +PT
Sbjct: 83 LVQFYSSWCGHCIAYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 221 LYFERGQFRFPYNGEN 236
YF+ F GEN
Sbjct: 143 RYFKAFTKEFT-TGEN 157
Score = 43.2 bits (97), Expect = 0.003
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SRFGVKGYPTL 346
LV FY+ WCGHC P + A ++ +AA+D +E + A + + YPT
Sbjct: 83 LVQFYSSWCGHCIAYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 347 KYFNKGEFKFDAG 359
+YF +F G
Sbjct: 143 RYFKAFTKEFTTG 155
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAE--NPKAADFAGIQTLPTF 597
+V FY++WC HC+ P + LA ++ ++ AL+ E N I PTF
Sbjct: 83 LVQFYSSWCGHCIAYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 598 KLFAA 602
+ F A
Sbjct: 143 RYFKA 147
>AF361868-1|AAM00263.1| 604|Homo sapiens sulfhydryl oxidase
protein.
Length = 604
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 116 PGFPTVRFFK 125
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
Query: 471 YFSYFDK 477
+F F K
Sbjct: 123 FFKAFTK 129
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 53 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 113 FNIPGFPTVRFF 124
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 121
Query: 598 KLFAA 602
+ F A
Sbjct: 122 RFFKA 126
>AB209280-1|BAD92517.1| 753|Homo sapiens quiescin Q6 isoform a
variant protein.
Length = 753
Score = 53.6 bits (123), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+C + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 62 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 121
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 122 PGFPTVRFFK 131
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGHC + P + AE A + A+DC + +C ++N+ G+PT++
Sbjct: 69 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 128
Query: 471 YFSYFDK 477
+F F K
Sbjct: 129 FFKAFTK 135
Score = 49.6 bits (113), Expect = 3e-05
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGHC P ++ A +K + LAA+D +E + A
Sbjct: 59 AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 118
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 119 FNIPGFPTVRFF 130
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC HC+ P + LA +K + AL+ AE +A DF I PT
Sbjct: 69 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 127
Query: 598 KLFAA 602
+ F A
Sbjct: 128 RFFKA 132
>CR392000-1|CAM28352.1| 698|Homo sapiens quiescin Q6-like 1
protein.
Length = 698
Score = 53.2 bits (122), Expect = 3e-06
Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 397 LDSSTFRN-TLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDC--T 452
LDS + R T +V FY+ WCGHC P + A D + A+DC
Sbjct: 66 LDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEE 125
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQ 486
+Q +C +Y++ YPT +YF F K++T G+
Sbjct: 126 KNQAVCHDYDIHFYPTFRYFKAF---TKEFTTGE 156
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLK--GESI-LAAIDVAKPGNSKIRQLYNITGFPTL 220
++ FY+ WCG+C P + AGD++ +I +AA+D + N + Y+I +PT
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 221 LYFERGQFRFPYNGEN 236
YF+ F GEN
Sbjct: 143 RYFKAFTKEFT-TGEN 157
Score = 42.7 bits (96), Expect = 0.004
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SRFGVKGYPTL 346
LV FY+ WCGHC P + A ++ +AA+D +E + A + + YPT
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 347 KYFNKGEFKFDAG 359
+YF +F G
Sbjct: 143 RYFKAFTKEFTTG 155
Score = 41.1 bits (92), Expect = 0.012
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAE--NPKAADFAGIQTLPTF 597
+V FY++WC HC+ P + LA ++ ++ AL+ E N I PTF
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 598 KLFAA 602
+ F A
Sbjct: 143 RYFKA 147
>AL138781-1|CAI16881.2| 698|Homo sapiens quiescin Q6-like 1
protein.
Length = 698
Score = 53.2 bits (122), Expect = 3e-06
Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 397 LDSSTFRN-TLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFAD-ELMVAFGAVDC--T 452
LDS + R T +V FY+ WCGHC P + A D + A+DC
Sbjct: 66 LDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEE 125
Query: 453 LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQ 486
+Q +C +Y++ YPT +YF F K++T G+
Sbjct: 126 KNQAVCHDYDIHFYPTFRYFKAF---TKEFTTGE 156
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLK--GESI-LAAIDVAKPGNSKIRQLYNITGFPTL 220
++ FY+ WCG+C P + AGD++ +I +AA+D + N + Y+I +PT
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 221 LYFERGQFRFPYNGEN 236
YF+ F GEN
Sbjct: 143 RYFKAFTKEFT-TGEN 157
Score = 42.7 bits (96), Expect = 0.004
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SRFGVKGYPTL 346
LV FY+ WCGHC P + A ++ +AA+D +E + A + + YPT
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 347 KYFNKGEFKFDAG 359
+YF +F G
Sbjct: 143 RYFKAFTKEFTTG 155
Score = 41.1 bits (92), Expect = 0.012
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAE--NPKAADFAGIQTLPTF 597
+V FY++WC HC+ P + LA ++ ++ AL+ E N I PTF
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 598 KLFAA 602
+ F A
Sbjct: 143 RYFKA 147
>U78678-1|AAB41631.1| 166|Homo sapiens thioredoxin protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>CR541917-1|CAG46715.1| 166|Homo sapiens TXN2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>CR541896-1|CAG46694.1| 166|Homo sapiens TXN2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>CR456601-1|CAG30487.1| 166|Homo sapiens TXN2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>BC050610-1|AAH50610.1| 166|Homo sapiens thioredoxin 2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>BC013726-1|AAH13726.1| 166|Homo sapiens thioredoxin 2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>AL022313-1|CAI19226.1| 197|Homo sapiens thioredoxin 2 protein.
Length = 197
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 97 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 153
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 154 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 193
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 113 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 170
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 171 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 197
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 113 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 170
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 171 KNGDVVDKFVGIKDEDQLEAFLK 193
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 100 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 156
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 157 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 194
>AF480262-1|AAN05576.1| 166|Homo sapiens mitochondrial thioredoxin
protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>AF276920-1|AAF86467.1| 166|Homo sapiens thioredoxin 2 protein.
Length = 166
Score = 52.4 bits (120), Expect = 5e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 274 NGDSFDAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+G F + +E +VV F+A WCG CK + P EK K + K+ ++A VD
Sbjct: 66 DGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK-QHGKV--VMAKVDIDDHT 122
Query: 333 DLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISFIK 372
DLA + V PT+ G+ + EDQ+ +F+K
Sbjct: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLK 162
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
+V F+A WCG CK P K + ++++A VD H DL Y V PT+
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMA--KVDIDDHTDLAIEYEVSAVPTVLAM 139
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQMG 500
D V + G + E +F+ +G
Sbjct: 140 KNGD-VVDKFVGIKDEDQLEAFLKKLIG 166
Score = 38.7 bits (86), Expect = 0.062
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+A WCG CK + P + G+ ++A +D+ + I Y ++ PT+L
Sbjct: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIE--YEVSAVPTVLAM 139
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
+ G + G + F++
Sbjct: 140 KNGDVVDKFVGIKDEDQLEAFLK 162
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 528 DFE-KIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
DF+ ++++ TP +V F+A WC C P RL + ++ V ++ ++ A
Sbjct: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLA 125
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKR 624
+ +PT G V + G + + L F K+
Sbjct: 126 IEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKK 163
>X77584-1|CAA54687.1| 105|Homo sapiens ATL-derived
factor/thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>X54539-1|CAA38410.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>CR407665-1|CAG28593.1| 105|Homo sapiens TXN protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>BC054866-1|AAH54866.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>BC003377-1|AAH03377.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>AY004872-1|AAF87085.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>AL158158-1|CAI14066.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>AF548001-1|AAN33187.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>AF313911-1|AAG34699.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 51.6 bits (118), Expect = 8e-06
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK KP F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCMPTFQFFKKGQK-VGEFSGANKE 95
Score = 49.6 bits (113), Expect = 3e-05
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK IKP F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCMPTFQFFKKGQ 84
Score = 39.9 bits (89), Expect = 0.027
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C KP F L+ K NV V ++ ++ A ++ +PTF+
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCMPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 36.7 bits (81), Expect = 0.25
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK +KP + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMIKP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCMPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>J04026-1|AAA74596.1| 105|Homo sapiens thioredoxin protein.
Length = 105
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK P F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMINPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCTPTFQFFKKGQK-VGEFSGANKE 95
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK I P F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMINPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCTPTFQFFKKGQ 84
Score = 36.7 bits (81), Expect = 0.25
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C P F L+ K NV V ++ ++ A ++ PTF+
Sbjct: 24 VVDFSATWCGPCKMINPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCTPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 33.9 bits (74), Expect = 1.8
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK + P + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMINP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCTPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>AF276919-1|AAF86466.1| 105|Homo sapiens thioredoxin 1 protein.
Length = 105
Score = 49.2 bits (112), Expect = 4e-05
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVD 450
V+ ++S T F+ L +V+ F A WCG CK P F +E++++ + + D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMINPFFHSLSEKYSNVIFLEVDVDD 61
Query: 451 CTLHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
C QD+ + VK PT ++F K V +++G KE
Sbjct: 62 C---QDVASECEVKCTPTFQFFKKGQK-VGEFSGANKE 95
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
+A+ A + +VV F A WCG CK I P F + K N I VD D+AS
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMINPFFHSLSEKYS----NVIFLEVDVDDCQDVASE 68
Query: 338 FGVKGYPTLKYFNKGE 353
VK PT ++F KG+
Sbjct: 69 CEVKCTPTFQFFKKGQ 84
Score = 36.7 bits (81), Expect = 0.25
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F ATWC C P F L+ K NV V ++ ++ A ++ PTF+
Sbjct: 24 VVDFSATWCGPCKMINPFFHSLSE--KYSNVIFLEVDVDDCQD--VASECEVKCTPTFQF 79
Query: 600 FAAGKYVTDYDG 611
F G+ V ++ G
Sbjct: 80 FKKGQKVGEFSG 91
Score = 33.9 bits (74), Expect = 1.8
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 161 KRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTL 220
K ++ F A WCG CK + P + + + I +DV + + PT
Sbjct: 21 KLVVVDFSATWCGPCKMINP-FFHSLSEKYSNVIFLEVDV--DDCQDVASECEVKCTPTF 77
Query: 221 LYFERGQFRFPYNGENKRQ 239
+F++GQ ++G NK +
Sbjct: 78 QFFKKGQKVGEFSGANKEK 96
>L42379-1|AAA89173.1| 793|Homo sapiens bone-derived growth factor
protein.
Length = 793
Score = 48.8 bits (111), Expect = 6e-05
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 158 GSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKG---ESILAAIDVAKPGNSKIRQLYNI 214
GS + F+A WCG+ + P + A D+K LAA+D A+ NS + + +NI
Sbjct: 58 GSRSAWAVEFFASWCGHSIAFAPTWKALAEDVKRWRPALYLAALDCAEETNSAVCRDFNI 117
Query: 215 TGFPTLLYFE 224
GFPT+ +F+
Sbjct: 118 PGFPTVRFFK 127
Score = 45.6 bits (103), Expect = 5e-04
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAF-GAVDCT--LHQDLCANYNVKGYPTIK 470
V F+A WCGH + P + AE + A+DC + +C ++N+ G+PT++
Sbjct: 65 VEFFASWCGHSIAFAPTWKALAEDVKRWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 124
Query: 471 YFSYFDK 477
+F F K
Sbjct: 125 FFKAFTK 131
Score = 45.2 bits (102), Expect = 7e-04
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 280 AILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA--SR 337
A+L V F+A WCGH P ++ A +K + LAA+D +E + A
Sbjct: 55 AVLGSRSAWAVEFFASWCGHSIAFAPTWKALAEDVKRWRPALYLAALDCAEETNSAVCRD 114
Query: 338 FGVKGYPTLKYF 349
F + G+PT+++F
Sbjct: 115 FNIPGFPTVRFF 126
Score = 37.9 bits (84), Expect = 0.11
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 541 VMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA---DFAGIQTLPTF 597
V F+A+WC H + P + LA +K + AL+ AE +A DF I PT
Sbjct: 65 VEFFASWCGHSIAFAPTWKALAEDVKRWRPALYLAALDCAEETNSAVCRDF-NIPGFPTV 123
Query: 598 KLFAA 602
+ F A
Sbjct: 124 RFFKA 128
>BC107425-1|AAI07426.1| 332|Homo sapiens DNAJC10 protein protein.
Length = 332
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
>AY089971-1|AAM09954.1| 275|Homo sapiens macrothioredoxin isoform 1
protein.
Length = 275
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
>AY010234-1|AAG32626.1| 332|Homo sapiens endoplasmic reticulum
DnaJ/PDI fusion protein 3 precursor protein.
Length = 332
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
>AC073951-1|AAX88931.1| 329|Homo sapiens unknown protein.
Length = 329
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGIL--A 324
D +++ L FDA + E V FY+P C HC + P + A ++++G+L
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-----KEVDGLLRIG 182
Query: 325 AVDATKEPDLASRFGVKGYPTLKYFNKGEFKFDAGHARQEDQIISF 370
AV+ + L GV YP+L F G R ++ ++SF
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
Score = 45.2 bits (102), Expect = 7e-04
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 528 DFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAAD 587
+F+ ++ V FY+ CSHC P + A K + ++ A+ ++
Sbjct: 138 EFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCR 194
Query: 588 FAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRH 625
G+ + P+ +F +G Y GDRS E L+ F +H
Sbjct: 195 MKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQH 232
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/80 (21%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 165 IMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYFE 224
+ FY+P C +C + P + + A ++ G + A++ + + ++ + +P+L F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCG--DDRMLCRMKGVNSYPSLFIFR 208
Query: 225 RGQFRFPYNGENKRQAIVEF 244
G Y+G+ ++++V F
Sbjct: 209 SGMAPVKYHGDRSKESLVSF 228
Score = 42.7 bits (96), Expect = 0.004
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 414 VMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYFS 473
V FY+P C HC P + A++ D L+ GAV+C + LC V YP++ F
Sbjct: 151 VNFYSPGCSHCHDLAPTWRDFAKE-VDGLL-RIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
Query: 474 YFDKAVKDYTGGQKEGDFVSF 494
VK Y G + + VSF
Sbjct: 209 SGMAPVK-YHGDRSKESLVSF 228
>BC130551-1|AAI30552.1| 115|Homo sapiens thioredoxin domain
containing 8 protein.
Length = 115
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 276 DSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
+ F L A H L V F + CG CKR+ P F + K + N A VD P+
Sbjct: 9 NEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQ----NVFFANVDVNNSPE 64
Query: 334 LASRFGVKGYPTLKYFNKGE 353
LA +K PT + F K +
Sbjct: 65 LAETCHIKTIPTFQMFKKSQ 84
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F + C C P F A ++K +NV V + +P+ A+ I+T+PTF++
Sbjct: 24 VVQFSSKRCGPCKRMFPVFH--AMSVKYQNVFFANV--DVNNSPELAETCHIKTIPTFQM 79
Query: 600 FAAGKYVT 607
F + VT
Sbjct: 80 FKKSQKVT 87
Score = 32.3 bits (70), Expect = 5.4
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 398 DSSTFRNTLRKIKH--SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQ 455
D++ F+ L H ++V F + CG CK P F + ++ + V F VD
Sbjct: 7 DTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQN---VFFANVDVNNSP 63
Query: 456 DLCANYNVKGYPTIKYFSYFDK 477
+L ++K PT + F K
Sbjct: 64 ELAETCHIKTIPTFQMFKKSQK 85
>BC130549-1|AAI30550.1| 115|Homo sapiens thioredoxin domain
containing 8 protein.
Length = 115
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 276 DSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
+ F L A H L V F + CG CKR+ P F + K + N A VD P+
Sbjct: 9 NEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQ----NVFFANVDVNNSPE 64
Query: 334 LASRFGVKGYPTLKYFNKGE 353
LA +K PT + F K +
Sbjct: 65 LAETCHIKTIPTFQMFKKSQ 84
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F + C C P F A ++K +NV V + +P+ A+ I+T+PTF++
Sbjct: 24 VVQFSSKRCGPCKRMFPVFH--AMSVKYQNVFFANV--DVNNSPELAETCHIKTIPTFQM 79
Query: 600 FAAGKYVT 607
F + VT
Sbjct: 80 FKKSQKVT 87
Score = 32.3 bits (70), Expect = 5.4
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 398 DSSTFRNTLRKIKH--SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQ 455
D++ F+ L H ++V F + CG CK P F + ++ + V F VD
Sbjct: 7 DTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQN---VFFANVDVNNSP 63
Query: 456 DLCANYNVKGYPTIKYFSYFDK 477
+L ++K PT + F K
Sbjct: 64 ELAETCHIKTIPTFQMFKKSQK 85
>AF305830-1|AAQ14501.1| 115|Homo sapiens thioredoxin 6 protein.
Length = 115
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 276 DSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPD 333
+ F L A H L V F + CG CKR+ P F + K + N A VD P+
Sbjct: 9 NEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQ----NVFFANVDVNNSPE 64
Query: 334 LASRFGVKGYPTLKYFNKGE 353
LA +K PT + F K +
Sbjct: 65 LAETCHIKTIPTFQMFKKSQ 84
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F + C C P F A ++K +NV V + +P+ A+ I+T+PTF++
Sbjct: 24 VVQFSSKRCGPCKRMFPVFH--AMSVKYQNVFFANV--DVNNSPELAETCHIKTIPTFQM 79
Query: 600 FAAGKYVT 607
F + VT
Sbjct: 80 FKKSQKVT 87
Score = 32.3 bits (70), Expect = 5.4
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 398 DSSTFRNTLRKIKH--SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQ 455
D++ F+ L H ++V F + CG CK P F + ++ + V F VD
Sbjct: 7 DTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQN---VFFANVDVNNSP 63
Query: 456 DLCANYNVKGYPTIKYFSYFDK 477
+L ++K PT + F K
Sbjct: 64 ELAETCHIKTIPTFQMFKKSQK 85
>BC044936-1|AAH44936.1| 584|Homo sapiens protein disulfide
isomerase-like protein of the testis protein.
Length = 584
Score = 43.6 bits (98), Expect = 0.002
Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 13/179 (7%)
Query: 182 YVEAAGDLKGESILAAIDVAKPGNSKIRQLYNIT--GFPTLLYFERG---QFRFPYNGEN 236
Y A+ + + + + +D +P N ++ + + +T P++ +++ P + +
Sbjct: 296 YKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMP-SDDI 354
Query: 237 KRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDSFDAILA-KAEHALVVFY 293
+++ +F R +++ K + + + + W + V L G +F+ ++ K + V+FY
Sbjct: 355 TYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGL-VKQLVGKNFNVVVFDKEKDVFVMFY 413
Query: 294 APWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
APW CK + P E+ K + I+A +D T D+ + + YP + F G
Sbjct: 414 APWSKKCKMLFPLLEELGRKYQNHS-TIIIAKIDVTAN-DIQLMY-LDRYPFFRLFPSG 469
Score = 39.1 bits (87), Expect = 0.047
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYP 467
K K VMFYAPW CK P + ++ + + +D T + D+ Y + YP
Sbjct: 404 KEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTAN-DIQLMY-LDRYP 461
Query: 468 TIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTK 502
+ F + Y G F F+ + + TK
Sbjct: 462 FFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTK 496
Score = 36.3 bits (80), Expect = 0.33
Identities = 56/225 (24%), Positives = 100/225 (44%), Gaps = 24/225 (10%)
Query: 40 LVLFVNEMKKAHNMV-EVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSP-EKPF-- 95
++LFV++ +++ ++ + +K + + + IL+D + N ++ K +V+ + P
Sbjct: 278 MLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQ 337
Query: 96 ILKHYKDGDFNKDYD--RSESVSSMC-NFL-RDPTGDLPWEEDPTAVD--IYHLLDGEA- 148
IL D + D ES+ +FL ++ T EE P D + L G+
Sbjct: 338 ILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNF 397
Query: 149 -IVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGES--ILAAIDVAKPGN 205
+V F K+ K +MFYAPW CK + P E + S I+A IDV
Sbjct: 398 NVVVFDKE-----KDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTA--- 449
Query: 206 SKIRQLYNITGFPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPV 249
+ I+ +Y + +P F G Q Y GE+ + +F+ +
Sbjct: 450 NDIQLMY-LDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHI 493
Score = 32.7 bits (71), Expect = 4.1
Identities = 31/141 (21%), Positives = 54/141 (38%), Gaps = 9/141 (6%)
Query: 493 SFIHNQMGTKQTSQKAPKTTQDAGFGANVLLAFDDDFEKII-SVPTPTIVMFYATWCSHC 551
SF+ Q+S++ PK D G ++ +F ++ VMFYA W C
Sbjct: 365 SFLSKNATKHQSSEEIPKYW-DQGLVKQLV---GKNFNVVVFDKEKDVFVMFYAPWSKKC 420
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAG-KYVTDYD 610
P L + + + A ++ N + P F+LF +G + Y
Sbjct: 421 KMLFPLLEELGRKYQNHSTIIIA-KIDVTAND--IQLMYLDRYPFFRLFPSGSQQAVLYK 477
Query: 611 GDRSTEDLLKFCKRHAEVKDE 631
G+ + + F + H + K E
Sbjct: 478 GEHTLKGFSDFLESHIKTKIE 498
>BC042607-1|AAH42607.1| 584|Homo sapiens protein disulfide
isomerase-like protein of the testis protein.
Length = 584
Score = 43.6 bits (98), Expect = 0.002
Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 13/179 (7%)
Query: 182 YVEAAGDLKGESILAAIDVAKPGNSKIRQLYNIT--GFPTLLYFERG---QFRFPYNGEN 236
Y A+ + + + + +D +P N ++ + + +T P++ +++ P + +
Sbjct: 296 YKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMP-SDDI 354
Query: 237 KRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDSFDAILA-KAEHALVVFY 293
+++ +F R +++ K + + + + W + V L G +F+ ++ K + V+FY
Sbjct: 355 TYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGL-VKQLVGKNFNVVVFDKEKDVFVMFY 413
Query: 294 APWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
APW CK + P E+ K + I+A +D T D+ + + YP + F G
Sbjct: 414 APWSKKCKMLFPLLEELGRKYQNHS-TIIIAKIDVTAN-DIQLMY-LDRYPFFRLFPSG 469
Score = 39.1 bits (87), Expect = 0.047
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYP 467
K K VMFYAPW CK P + ++ + + +D T + D+ Y + YP
Sbjct: 404 KEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTAN-DIQLMY-LDRYP 461
Query: 468 TIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTK 502
+ F + Y G F F+ + + TK
Sbjct: 462 FFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTK 496
Score = 36.3 bits (80), Expect = 0.33
Identities = 56/225 (24%), Positives = 100/225 (44%), Gaps = 24/225 (10%)
Query: 40 LVLFVNEMKKAHNMV-EVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSP-EKPF-- 95
++LFV++ +++ ++ + +K + + + IL+D + N ++ K +V+ + P
Sbjct: 278 MLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQ 337
Query: 96 ILKHYKDGDFNKDYD--RSESVSSMC-NFL-RDPTGDLPWEEDPTAVD--IYHLLDGEA- 148
IL D + D ES+ +FL ++ T EE P D + L G+
Sbjct: 338 ILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNF 397
Query: 149 -IVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGES--ILAAIDVAKPGN 205
+V F K+ K +MFYAPW CK + P E + S I+A IDV
Sbjct: 398 NVVVFDKE-----KDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTA--- 449
Query: 206 SKIRQLYNITGFPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPV 249
+ I+ +Y + +P F G Q Y GE+ + +F+ +
Sbjct: 450 NDIQLMY-LDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHI 493
Score = 32.7 bits (71), Expect = 4.1
Identities = 31/141 (21%), Positives = 54/141 (38%), Gaps = 9/141 (6%)
Query: 493 SFIHNQMGTKQTSQKAPKTTQDAGFGANVLLAFDDDFEKII-SVPTPTIVMFYATWCSHC 551
SF+ Q+S++ PK D G ++ +F ++ VMFYA W C
Sbjct: 365 SFLSKNATKHQSSEEIPKYW-DQGLVKQLV---GKNFNVVVFDKEKDVFVMFYAPWSKKC 420
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAG-KYVTDYD 610
P L + + + A ++ N + P F+LF +G + Y
Sbjct: 421 KMLFPLLEELGRKYQNHSTIIIA-KIDVTAND--IQLMYLDRYPFFRLFPSGSQQAVLYK 477
Query: 611 GDRSTEDLLKFCKRHAEVKDE 631
G+ + + F + H + K E
Sbjct: 478 GEHTLKGFSDFLESHIKTKIE 498
>AK097476-1|BAC05068.1| 584|Homo sapiens protein ( Homo sapiens
cDNA FLJ40157 fis, clone TESTI2014800, weakly similar to
PROTEIN DISULFIDE ISOMERASE (EC 5.3.4.1). ).
Length = 584
Score = 43.6 bits (98), Expect = 0.002
Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 13/179 (7%)
Query: 182 YVEAAGDLKGESILAAIDVAKPGNSKIRQLYNIT--GFPTLLYFERG---QFRFPYNGEN 236
Y A+ + + + + +D +P N ++ + + +T P++ +++ P + +
Sbjct: 296 YKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMP-SDDI 354
Query: 237 KRQAIVEFMRDPVAQ--PKQKKKDVVDESWARDTDVVHLNGDSFDAILA-KAEHALVVFY 293
+++ +F R +++ K + + + + W + V L G +F+ ++ K + V+FY
Sbjct: 355 TYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGL-VKQLVGKNFNVVVFDKEKDVFVMFY 413
Query: 294 APWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKYFNKG 352
APW CK + P E+ K + I+A +D T D+ + + YP + F G
Sbjct: 414 APWSKKCKMLFPLLEELGRKYQNHS-TIIIAKIDVTAN-DIQLMY-LDRYPFFRLFPSG 469
Score = 39.1 bits (87), Expect = 0.047
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 408 KIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYP 467
K K VMFYAPW CK P + ++ + + +D T + D+ Y + YP
Sbjct: 404 KEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTAN-DIQLMY-LDRYP 461
Query: 468 TIKYFSYFDKAVKDYTGGQKEGDFVSFIHNQMGTK 502
+ F + Y G F F+ + + TK
Sbjct: 462 FFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTK 496
Score = 36.3 bits (80), Expect = 0.33
Identities = 56/225 (24%), Positives = 100/225 (44%), Gaps = 24/225 (10%)
Query: 40 LVLFVNEMKKAHNMV-EVFKETADTMRGQATLILIDCNNSDNKKLCKKLKVSP-EKPF-- 95
++LFV++ +++ ++ + +K + + + IL+D + N ++ K +V+ + P
Sbjct: 278 MLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQ 337
Query: 96 ILKHYKDGDFNKDYD--RSESVSSMC-NFL-RDPTGDLPWEEDPTAVD--IYHLLDGEA- 148
IL D + D ES+ +FL ++ T EE P D + L G+
Sbjct: 338 ILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNF 397
Query: 149 -IVKFLKKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEAAGDLKGES--ILAAIDVAKPGN 205
+V F K+ K +MFYAPW CK + P E + S I+A IDV
Sbjct: 398 NVVVFDKE-----KDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTA--- 449
Query: 206 SKIRQLYNITGFPTLLYFERG-QFRFPYNGENKRQAIVEFMRDPV 249
+ I+ +Y + +P F G Q Y GE+ + +F+ +
Sbjct: 450 NDIQLMY-LDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHI 493
Score = 32.7 bits (71), Expect = 4.1
Identities = 31/141 (21%), Positives = 54/141 (38%), Gaps = 9/141 (6%)
Query: 493 SFIHNQMGTKQTSQKAPKTTQDAGFGANVLLAFDDDFEKII-SVPTPTIVMFYATWCSHC 551
SF+ Q+S++ PK D G ++ +F ++ VMFYA W C
Sbjct: 365 SFLSKNATKHQSSEEIPKYW-DQGLVKQLV---GKNFNVVVFDKEKDVFVMFYAPWSKKC 420
Query: 552 VTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKLFAAG-KYVTDYD 610
P L + + + A ++ N + P F+LF +G + Y
Sbjct: 421 KMLFPLLEELGRKYQNHSTIIIA-KIDVTAND--IQLMYLDRYPFFRLFPSGSQQAVLYK 477
Query: 611 GDRSTEDLLKFCKRHAEVKDE 631
G+ + + F + H + K E
Sbjct: 478 GEHTLKGFSDFLESHIKTKIE 498
>CR457152-1|CAG33433.1| 330|Homo sapiens LOC51061 protein.
Length = 330
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 94
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 95 QN-DLPWEFMVDRLPTVLFF 113
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 56 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 112
Query: 223 F 223
F
Sbjct: 113 F 113
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 94
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 95 -QNDLPWEFMVDRLPTVLFF 113
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 43 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 100
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGD--RSTEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 101 EFM-VDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSD 144
>BC050132-1|AAH50132.1| 486|Homo sapiens thioredoxin domain
containing 2 (spermatozoa) protein.
Length = 486
Score = 43.2 bits (97), Expect = 0.003
Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%)
Query: 271 VHLNGDSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
V L+ + F+A L +A LV F A WCG C+ I+P F A +K E + + VDA
Sbjct: 385 VILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH--ALSVKHEDV--VFLEVDA 440
Query: 329 TKEPDLASRFGVKGYPTLKYFNKGE 353
++ + PT +++ K E
Sbjct: 441 DNCEEVVRECAIMCVPTFQFYKKEE 465
Score = 33.5 bits (73), Expect = 2.3
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLH 454
L F +L++ +V F A WCG C++ +P F + + D V F VD
Sbjct: 387 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHED---VVFLEVDADNC 443
Query: 455 QDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
+++ + PT +++ +K V + G KE
Sbjct: 444 EEVVRECAIMCVPTFQFYKKEEK-VDELCGALKE 476
Score = 33.1 bits (72), Expect = 3.1
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
Query: 527 DDFEKIISVPTPTIVM--FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
+DFE + +V F ATWC C T +P F A ++K E+V V + E +
Sbjct: 390 EDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH--ALSVKHEDVVFLEVDADNCE--E 445
Query: 585 AADFAGIQTLPTFKLFAAGKYVTDYDG 611
I +PTF+ + + V + G
Sbjct: 446 VVRECAIMCVPTFQFYKKEEKVDELCG 472
>BC033787-1|AAH33787.1| 349|Homo sapiens thioredoxin domain
containing 13 protein.
Length = 349
Score = 43.2 bits (97), Expect = 0.003
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C++ E+E A + +I+ + VD +EP L+ RF V P +
Sbjct: 56 MLKFYAPWCPSCQQTDSEWEAFAKNGEILQIS--VGKVDVIQEPGLSGRFFVTTLPAFFH 113
Query: 349 FNKGEFKFDAGHARQED 365
G F+ G ED
Sbjct: 114 AKDGIFRRYRGPGIFED 130
Score = 35.9 bits (79), Expect = 0.44
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C+ T E+ +A + + L ++ G VD L + V P +F
Sbjct: 56 MLKFYAPWCPSCQQTDSEW-EAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPA--FF 112
Query: 473 SYFDKAVKDYTG 484
D + Y G
Sbjct: 113 HAKDGIFRRYRG 124
>BC013727-1|AAH13727.1| 330|Homo sapiens TXNDC11 protein protein.
Length = 330
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 94
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 95 QN-DLPWEFMVDRLPTVLFF 113
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 56 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 112
Query: 223 F 223
F
Sbjct: 113 F 113
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 94
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 95 -QNDLPWEFMVDRLPTVLFF 113
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 43 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 100
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGD--RSTEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 101 EFM-VDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSD 144
>BC002856-1|AAH02856.1| 985|Homo sapiens TXNDC11 protein protein.
Length = 985
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 692 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 749
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 750 QN-DLPWEFMVDRLPTVLFF 768
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 711 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 767
Query: 223 F 223
F
Sbjct: 768 F 768
Score = 41.5 bits (93), Expect = 0.009
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWCG + + E +AA + +D+ V F A++C +Q C Y + Y
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQ--VLFVAINCWWNQGKCRKQKHFFYFPVIYL 186
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQM 499
+ +Y G F+ M
Sbjct: 187 YHRSFGPIEYKGPMSAVYIEKFVRRVM 213
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG + + + +AA L + + AI+ K R+ + FP + +
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAIN-CWWNQGKCRKQKHFFYFPVIYLY 187
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
R Y G I +F+R
Sbjct: 188 HRSFGPIEYKGPMSAVYIEKFVR 210
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 692 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 749
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 750 -QNDLPWEFMVDRLPTVLFF 768
Score = 35.5 bits (78), Expect = 0.58
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 276 DSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTE 317
D + + +E L+ FYAPWCG + E E+AA+++ +
Sbjct: 116 DYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQ 157
Score = 35.1 bits (77), Expect = 0.76
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 698 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 755
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGDR--STEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 756 EFM-VDRLPTVLFFPCNRKDLSVKYPEDLPITLPNLLRFILHHSD 799
>AY359004-1|AAQ89363.1| 349|Homo sapiens DJ971N18.2 protein.
Length = 349
Score = 43.2 bits (97), Expect = 0.003
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C++ E+E A + +I+ + VD +EP L+ RF V P +
Sbjct: 56 MLKFYAPWCPSCQQTDSEWEAFAKNGEILQIS--VGKVDVIQEPGLSGRFFVTTLPAFFH 113
Query: 349 FNKGEFKFDAGHARQED 365
G F+ G ED
Sbjct: 114 AKDGIFRRYRGPGIFED 130
Score = 35.9 bits (79), Expect = 0.44
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C+ T E+ +A + + L ++ G VD L + V P +F
Sbjct: 56 MLKFYAPWCPSCQQTDSEW-EAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPA--FF 112
Query: 473 SYFDKAVKDYTG 484
D + Y G
Sbjct: 113 HAKDGIFRRYRG 124
>AL021396-2|CAC17521.1| 349|Homo sapiens thioredoxin domain
containing 13 protein.
Length = 349
Score = 43.2 bits (97), Expect = 0.003
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C++ E+E A + +I+ + VD +EP L+ RF V P +
Sbjct: 56 MLKFYAPWCPSCQQTDSEWEAFAKNGEILQIS--VGKVDVIQEPGLSGRFFVTTLPAFFH 113
Query: 349 FNKGEFKFDAGHARQED 365
G F+ G ED
Sbjct: 114 AKDGIFRRYRGPGIFED 130
Score = 35.9 bits (79), Expect = 0.44
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C+ T E+ +A + + L ++ G VD L + V P +F
Sbjct: 56 MLKFYAPWCPSCQQTDSEW-EAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPA--FF 112
Query: 473 SYFDKAVKDYTG 484
D + Y G
Sbjct: 113 HAKDGIFRRYRG 124
>AK075404-1|BAC11599.1| 349|Homo sapiens protein ( Homo sapiens
cDNA PSEC0095 fis, clone NT2RP2001768, moderately
similar to Thioredoxin-like protein KIAA1162 precursor.
).
Length = 349
Score = 43.2 bits (97), Expect = 0.003
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C++ E+E A + +I+ + VD +EP L+ RF V P +
Sbjct: 56 MLKFYAPWCPSCQQTDSEWEAFAKNGEILQIS--VGKVDVIQEPGLSGRFFVTTLPAFFH 113
Query: 349 FNKGEFKFDAGHARQED 365
G F+ G ED
Sbjct: 114 AKDGIFRRYRGPGIFED 130
Score = 35.9 bits (79), Expect = 0.44
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C+ T E+ +A + + L ++ G VD L + V P +F
Sbjct: 56 MLKFYAPWCPSCQQTDSEW-EAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPA--FF 112
Query: 473 SYFDKAVKDYTG 484
D + Y G
Sbjct: 113 HAKDGIFRRYRG 124
>AK074838-1|BAC11237.1| 349|Homo sapiens protein ( Homo sapiens
cDNA FLJ90357 fis, clone NT2RP2003593, moderately
similar to Thioredoxin-like protein KIAA1162 precursor.
).
Length = 349
Score = 43.2 bits (97), Expect = 0.003
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLKY 348
++ FYAPWC C++ E+E A + +I+ + VD +EP L+ RF V P +
Sbjct: 56 MLKFYAPWCPSCQQTDSEWEAFAKNGEILQIS--VGKVDVIQEPGLSGRFFVTTLPAFFH 113
Query: 349 FNKGEFKFDAGHARQED 365
G F+ G ED
Sbjct: 114 AKDGIFRRYRGPGIFED 130
Score = 35.9 bits (79), Expect = 0.44
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWC C+ T E+ +A + + L ++ G VD L + V P +F
Sbjct: 56 MLKFYAPWCPSCQQTDSEW-EAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPA--FF 112
Query: 473 SYFDKAVKDYTG 484
D + Y G
Sbjct: 113 HAKDGIFRRYRG 124
>AK027646-1|BAB55262.1| 958|Homo sapiens protein ( Homo sapiens
cDNA FLJ14740 fis, clone NT2RP3002602, weakly similar to
PROBABLE PROTEIN DISULFIDE ISOMERASE ER-60 PRECURSOR (EC
5.3.4.1). ).
Length = 958
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 665 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 722
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 723 QN-DLPWEFMVDRLPTVLFF 741
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 684 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 740
Query: 223 F 223
F
Sbjct: 741 F 741
Score = 41.5 bits (93), Expect = 0.009
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWCG + + E +AA + +D+ V F A++C +Q C Y + Y
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQ--VLFVAINCWWNQGKCRKQKHFFYFPVIYL 186
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQM 499
+ +Y G F+ M
Sbjct: 187 YHRSFGPIEYKGPMSAVYIEKFVRRVM 213
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG + + + +AA L + + AI+ K R+ + FP + +
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAIN-CWWNQGKCRKQKHFFYFPVIYLY 187
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
R Y G I +F+R
Sbjct: 188 HRSFGPIEYKGPMSAVYIEKFVR 210
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 665 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 722
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 723 -QNDLPWEFMVDRLPTVLFF 741
Score = 35.5 bits (78), Expect = 0.58
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 276 DSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTE 317
D + + +E L+ FYAPWCG + E E+AA+++ +
Sbjct: 116 DYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQ 157
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 671 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 728
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGD--RSTEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 729 EFM-VDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSD 772
>AK027464-1|BAB55129.1| 506|Homo sapiens protein ( Homo sapiens
cDNA FLJ14558 fis, clone NT2RM2001997, weakly similar to
PROTEIN DISULFIDE ISOMERASE PRECURSOR (EC 5.3.4.1). ).
Length = 506
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 213 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 270
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 271 QN-DLPWEFMVDRLPTVLFF 289
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 232 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 288
Query: 223 F 223
F
Sbjct: 289 F 289
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 213 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 270
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 271 -QNDLPWEFMVDRLPTVLFF 289
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 219 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 276
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGD--RSTEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 277 EFM-VDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSD 320
>AF131780-1|AAD20043.1| 330|Homo sapiens Unknown protein.
Length = 330
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 270 VVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDAT 329
+ + D+F ++ + + L+++YAPWCG C + F + A + + +A +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFT--VARIDVS 94
Query: 330 KEPDLASRFGVKGYPTLKYF 349
+ DL F V PT+ +F
Sbjct: 95 QN-DLPWEFMVDRLPTVLFF 113
Score = 41.9 bits (94), Expect = 0.007
Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESI-LAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++++YAPWCG+C S+ +++ A +L ++ +A IDV++ + + + + PT+L+
Sbjct: 56 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ---NDLPWEFMVDRLPTVLF 112
Query: 223 F 223
F
Sbjct: 113 F 113
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 394 VRHLDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQF-ADELMVAFGAVDCT 452
+ + + TF + + + ++++YAPWCG C S F++ A D VA +D +
Sbjct: 37 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVA--RIDVS 94
Query: 453 LHQDLCANYNVKGYPTIKYF 472
DL + V PT+ +F
Sbjct: 95 -QNDLPWEFMVDRLPTVLFF 113
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 527 DDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
D F +++ ++++YA WC C + F +LA L + V ++ ++N
Sbjct: 43 DTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTV--ARIDVSQNDLPW 100
Query: 587 DFAGIQTLPTFKLFAAGK--YVTDYDGD--RSTEDLLKFCKRHAE 627
+F + LPT F + Y D + +LL+F H++
Sbjct: 101 EFM-VDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSD 144
>AF080095-1|AAK94950.1| 486|Homo sapiens sperm-specific thioredoxin
protein.
Length = 486
Score = 43.2 bits (97), Expect = 0.003
Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%)
Query: 271 VHLNGDSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
V L+ + F+A L +A LV F A WCG C+ I+P F A +K E + + VDA
Sbjct: 385 VILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH--ALSVKHEDV--VFLEVDA 440
Query: 329 TKEPDLASRFGVKGYPTLKYFNKGE 353
++ + PT +++ K E
Sbjct: 441 DNCEEVVRECAIMCVPTFQFYKKEE 465
Score = 33.5 bits (73), Expect = 2.3
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLH 454
L F +L++ +V F A WCG C++ +P F + + D V F VD
Sbjct: 387 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHED---VVFLEVDADNC 443
Query: 455 QDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
+++ + PT +++ +K V + G KE
Sbjct: 444 EEVVRECAIMCVPTFQFYKKEEK-VDELCGALKE 476
Score = 33.1 bits (72), Expect = 3.1
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
Query: 527 DDFEKIISVPTPTIVM--FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
+DFE + +V F ATWC C T +P F A ++K E+V V + E +
Sbjct: 390 EDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH--ALSVKHEDVVFLEVDADNCE--E 445
Query: 585 AADFAGIQTLPTFKLFAAGKYVTDYDG 611
I +PTF+ + + V + G
Sbjct: 446 VVRECAIMCVPTFQFYKKEEKVDELCG 472
>AB037765-1|BAA92582.2| 858|Homo sapiens KIAA1344 protein protein.
Length = 858
Score = 42.7 bits (96), Expect = 0.004
Identities = 34/166 (20%), Positives = 79/166 (47%), Gaps = 12/166 (7%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLY 222
S+++FYA W + Y++ A LKG S + + S + N+T FP +
Sbjct: 443 SIVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKM 502
Query: 223 FERGQFRFPYNGENKRQAIVEFMR-DPVAQPKQKKKDVVDESWARDTDVVHLNGDSFDAI 281
+++G+ Y G + +++F++ + ++ P V+ + ++ + +L+G+ + +
Sbjct: 503 YKKGENPVSYAGMLGTKDLLKFIQLNRISYP-------VNITSIQEAE-EYLSGELYKDL 554
Query: 282 LAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVD 327
+ + +++ ++P K K +F +A +K I GI + D
Sbjct: 555 ILYSSVSVLGLFSP---TMKTAKEDFSEAGNYLKGYVITGIYSEED 597
Score = 39.9 bits (89), Expect = 0.027
Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 2/99 (2%)
Query: 397 LDSSTFRNTLRKIKHSIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQD 456
L TF T+ SIV+FYA W + ++ A + + ++C D
Sbjct: 429 LTEETFNATVMA-SDSIVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSD 487
Query: 457 LCANYNVKGYPTIKYFSYFDKAVKDYTGGQKEGDFVSFI 495
+C NV +P IK + + V Y G D + FI
Sbjct: 488 VCTKQNVTEFPIIKMYKKGENPV-SYAGMLGTKDLLKFI 525
Score = 34.7 bits (76), Expect = 1.0
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
+IV+FYA W + + ++ +A LK + + + A+ + P K
Sbjct: 443 SIVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTML-LTRINCADWSDVCTKQNVTEFPIIK 501
Query: 599 LFAAGKYVTDYDGDRSTEDLLKF 621
++ G+ Y G T+DLLKF
Sbjct: 502 MYKKGENPVSYAGMLGTKDLLKF 524
>AK097656-1|BAC05133.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ40337 fis, clone TESTI2032044, moderately
similar to THIOREDOXIN. ).
Length = 553
Score = 41.9 bits (94), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 271 VHLNGDSFDAILAKAEHALVV--FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
V L+ + F+A L +A LV F A WCG C+ I P F A +K E + + VDA
Sbjct: 452 VILSKEDFEASLKEAGERLVAVDFSATWCGPCRTITPFFH--ALSVKHEDV--VFLEVDA 507
Query: 329 TKEPDLASRFGVKGYPTLKYFNKGE 353
++ + PT +++ K E
Sbjct: 508 DNCEEVVRECAIMCVPTFQFYKKEE 532
Score = 32.3 bits (70), Expect = 5.4
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 397 LDSSTFRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLH 454
L F +L++ +V F A WCG C++ P F + + D V F VD
Sbjct: 454 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTITPFFHALSVKHED---VVFLEVDADNC 510
Query: 455 QDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQKE 488
+++ + PT +++ +K V + G KE
Sbjct: 511 EEVVRECAIMCVPTFQFYKKEEK-VDELCGALKE 543
Score = 31.9 bits (69), Expect = 7.1
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Query: 527 DDFEKIISVPTPTIVM--FYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPK 584
+DFE + +V F ATWC C T P F A ++K E+V V + E +
Sbjct: 457 EDFEASLKEAGERLVAVDFSATWCGPCRTITPFFH--ALSVKHEDVVFLEVDADNCE--E 512
Query: 585 AADFAGIQTLPTFKLFAAGKYVTDYDG 611
I +PTF+ + + V + G
Sbjct: 513 VVRECAIMCVPTFQFYKKEEKVDELCG 539
>BC018635-1|AAH18635.1| 278|Homo sapiens TXNDC11 protein protein.
Length = 278
Score = 41.5 bits (93), Expect = 0.009
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKYF 472
++ FYAPWCG + + E +AA + +D+ V F A++C +Q C Y + Y
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQ--VLFVAINCWWNQGKCRKQKHFFYFPVIYL 186
Query: 473 SYFDKAVKDYTGGQKEGDFVSFIHNQM 499
+ +Y G F+ M
Sbjct: 187 YHRSFGPIEYKGPMSAVYIEKFVRRVM 213
Score = 39.1 bits (87), Expect = 0.047
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ FYAPWCG + + + +AA L + + AI+ K R+ + FP + +
Sbjct: 129 LLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAIN-CWWNQGKCRKQKHFFYFPVIYLY 187
Query: 224 ERGQFRFPYNGENKRQAIVEFMR 246
R Y G I +F+R
Sbjct: 188 HRSFGPIEYKGPMSAVYIEKFVR 210
Score = 35.5 bits (78), Expect = 0.58
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 276 DSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTE 317
D + + +E L+ FYAPWCG + E E+AA+++ +
Sbjct: 116 DYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQ 157
>AL158158-4|CAI14069.1| 101|Homo sapiens thioredoxin domain
containing 8 protein.
Length = 101
Score = 41.5 bits (93), Expect = 0.009
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 288 ALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGYPTLK 347
A+V F + CG CKR+ P F + K + N A VD P+LA +K PT +
Sbjct: 9 AVVQFSSKRCGPCKRMFPVFHAMSVKYQ----NVFFANVDVNNSPELAETCHIKTIPTFQ 64
Query: 348 YFNKGE 353
F K +
Sbjct: 65 MFKKSQ 70
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 540 IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFKL 599
+V F + C C P F A ++K +NV V + +P+ A+ I+T+PTF++
Sbjct: 10 VVQFSSKRCGPCKRMFPVFH--AMSVKYQNVFFANV--DVNNSPELAETCHIKTIPTFQM 65
Query: 600 FAAGKYVT 607
F + VT
Sbjct: 66 FKKSQKVT 73
>BC005289-1|AAH05289.1| 335|Homo sapiens thioredoxin-like 2
protein.
Length = 335
Score = 40.7 bits (91), Expect = 0.015
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 529 FEKIISVPTPT--IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
FE+++ + + +V F+A W C + LA L V V LEA P+ +
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ----VSFVKLEAEGVPEVS 77
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ I ++PTF F + + DG + E L K +RHA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHAPE-LTKKVQRHA 116
Score = 36.3 bits (80), Expect = 0.33
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APW C M E A +L S + + G ++ + Y I+ PT L+F
Sbjct: 35 VVHFWAPWAPQCAQMNEVMAELAKELPQVSF---VKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 224 ERGQ 227
+ Q
Sbjct: 92 KNSQ 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 278 FDAILA-KAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA 335
F+ +L KA+ LVV F+APW C ++ + A ++ ++A P+++
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS----FVKLEAEGVPEVS 77
Query: 336 SRFGVKGYPTLKYFNKGE--FKFDAGHA 361
++ + PT +F + + D HA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHA 105
>AL139123-3|CAC40691.1| 335|Homo sapiens thioredoxin-like 3
protein.
Length = 335
Score = 40.7 bits (91), Expect = 0.015
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 529 FEKIISVPTPT--IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
FE+++ + + +V F+A W C + LA L V V LEA P+ +
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ----VSFVKLEAEGVPEVS 77
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ I ++PTF F + + DG + E L K +RHA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHAPE-LTKKVQRHA 116
Score = 36.3 bits (80), Expect = 0.33
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APW C M E A +L S + + G ++ + Y I+ PT L+F
Sbjct: 35 VVHFWAPWAPQCAQMNEVMAELAKELPQVSF---VKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 224 ERGQ 227
+ Q
Sbjct: 92 KNSQ 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 278 FDAILA-KAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA 335
F+ +L KA+ LVV F+APW C ++ + A ++ ++A P+++
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS----FVKLEAEGVPEVS 77
Query: 336 SRFGVKGYPTLKYFNKGE--FKFDAGHA 361
++ + PT +F + + D HA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHA 105
>AJ010841-1|CAA09375.1| 335|Homo sapiens thioredoxin-like protein
protein.
Length = 335
Score = 40.7 bits (91), Expect = 0.015
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 529 FEKIISVPTPT--IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
FE+++ + + +V F+A W C + LA L V V LEA P+ +
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ----VSFVKLEAEGVPEVS 77
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ I ++PTF F + + DG + E L K +RHA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHAPE-LTKKVQRHA 116
Score = 36.3 bits (80), Expect = 0.33
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APW C M E A +L S + + G ++ + Y I+ PT L+F
Sbjct: 35 VVHFWAPWAPQCAQMNEVMAELAKELPQVSF---VKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 224 ERGQ 227
+ Q
Sbjct: 92 KNSQ 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 278 FDAILA-KAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA 335
F+ +L KA+ LVV F+APW C ++ + A ++ ++A P+++
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS----FVKLEAEGVPEVS 77
Query: 336 SRFGVKGYPTLKYFNKGE--FKFDAGHA 361
++ + PT +F + + D HA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHA 105
>AF118652-1|AAF28844.1| 335|Homo sapiens PKCq-interacting protein
PICOT protein.
Length = 335
Score = 40.7 bits (91), Expect = 0.015
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 529 FEKIISVPTPT--IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
FE+++ + + +V F+A W C + LA L V V LEA P+ +
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ----VSFVKLEAEGVPEVS 77
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ I ++PTF F + + DG + E L K +RHA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHAPE-LTKKVQRHA 116
Score = 36.3 bits (80), Expect = 0.33
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APW C M E A +L S + + G ++ + Y I+ PT L+F
Sbjct: 35 VVHFWAPWAPQCAQMNEVMAELAKELPQVSF---VKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 224 ERGQ 227
+ Q
Sbjct: 92 KNSQ 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 278 FDAILA-KAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA 335
F+ +L KA+ LVV F+APW C ++ + A ++ ++A P+++
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS----FVKLEAEGVPEVS 77
Query: 336 SRFGVKGYPTLKYFNKGE--FKFDAGHA 361
++ + PT +F + + D HA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHA 105
>AF118649-1|AAF28841.1| 335|Homo sapiens PKCq-interacting protein
PICOT protein.
Length = 335
Score = 40.7 bits (91), Expect = 0.015
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 529 FEKIISVPTPT--IVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAA 586
FE+++ + + +V F+A W C + LA L V V LEA P+ +
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ----VSFVKLEAEGVPEVS 77
Query: 587 DFAGIQTLPTFKLFAAGKYVTDYDGDRSTEDLLKFCKRHA 626
+ I ++PTF F + + DG + E L K +RHA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHAPE-LTKKVQRHA 116
Score = 36.3 bits (80), Expect = 0.33
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 164 MIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLYF 223
++ F+APW C M E A +L S + + G ++ + Y I+ PT L+F
Sbjct: 35 VVHFWAPWAPQCAQMNEVMAELAKELPQVSF---VKLEAEGVPEVSEKYEISSVPTFLFF 91
Query: 224 ERGQ 227
+ Q
Sbjct: 92 KNSQ 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 278 FDAILA-KAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLA 335
F+ +L KA+ LVV F+APW C ++ + A ++ ++A P+++
Sbjct: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS----FVKLEAEGVPEVS 77
Query: 336 SRFGVKGYPTLKYFNKGE--FKFDAGHA 361
++ + PT +F + + D HA
Sbjct: 78 EKYEISSVPTFLFFKNSQKIDRLDGAHA 105
>BX538131-1|CAD98032.1| 355|Homo sapiens hypothetical protein
protein.
Length = 355
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 206 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 261
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 262 LFQGAKPMARFNHTDRTLETLKIF 285
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 187 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 242
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 243 SQHSSLSTRFGTVAVPNILLF 263
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 206 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 262
Query: 472 F 472
F
Sbjct: 263 F 263
>BC032568-1|AAH32568.1| 360|Homo sapiens chromosome 5 open reading
frame 14 protein.
Length = 360
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 266
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 267 LFQGAKPMARFNHTDRTLETLKIF 290
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 192 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 247
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 248 SQHSSLSTRFGTVAVPNILLF 268
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 267
Query: 472 F 472
F
Sbjct: 268 F 268
>BC008953-1|AAH08953.1| 172|Homo sapiens thioredoxin domain
containing 12 (endoplasmic reticulum) protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>BC008913-1|AAH08913.1| 172|Homo sapiens thioredoxin domain
containing 12 (endoplasmic reticulum) protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKHEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>BC001615-1|AAH01615.1| 360|Homo sapiens chromosome 5 open reading
frame 14 protein.
Length = 360
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 266
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 267 LFQGAKPMARFNHTDRTLETLKIF 290
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 192 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 247
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 248 SQHSSLSTRFGTVAVPNILLF 268
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 267
Query: 472 F 472
F
Sbjct: 268 F 268
>BC001493-1|AAH01493.1| 172|Homo sapiens thioredoxin domain
containing 12 (endoplasmic reticulum) protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>AY358982-1|AAQ89341.1| 172|Homo sapiens ETRP713 protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>AY358649-1|AAQ89012.1| 360|Homo sapiens disulfide isomerase
protein.
Length = 360
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 266
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 267 LFQGAKPMARFNHTDRTLETLKIF 290
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 192 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 247
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 248 SQHSSLSTRFGTVAVPNILLF 268
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 267
Query: 472 F 472
F
Sbjct: 268 F 268
>AL445685-5|CAI17031.1| 172|Homo sapiens thioredoxin domain
containing 12 (endoplasmic reticulum) protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>AK056512-1|BAB71199.1| 360|Homo sapiens protein ( Homo sapiens
cDNA FLJ31950 fis, clone NT2RP7007154. ).
Length = 360
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 266
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 267 LFQGAKPMARFNHTDRTLETLKIF 290
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 192 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 247
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 248 SQHSSLSTRFGTVAVPNILLF 268
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 211 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 267
Query: 472 F 472
F
Sbjct: 268 F 268
>AK026278-1|BAB15427.1| 343|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22625 fis, clone HSI06009. ).
Length = 343
Score = 36.3 bits (80), Expect = 0.33
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 539 TIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKAVALEAAENPKAADFAGIQTLPTFK 598
T+V+FY WC + P F+ L A + +AL+A+++ + G +P
Sbjct: 194 TLVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNIL 249
Query: 599 LFAAGKYVTDYD-GDRSTEDLLKF 621
LF K + ++ DR+ E L F
Sbjct: 250 LFQGAKPMARFNHTDRTLETLKIF 273
Score = 35.9 bits (79), Expect = 0.44
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 270 VVHLNGDSFDAILAK-AEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDA 328
+++++ D D + ++ LV+FY PWC + P F A+DA
Sbjct: 175 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH----FLALDA 230
Query: 329 TKEPDLASRFGVKGYPTLKYF 349
++ L++RFG P + F
Sbjct: 231 SQHSSLSTRFGTVAVPNILLF 251
Score = 35.5 bits (78), Expect = 0.58
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIKY 471
++V+FY PWC S P F F + F A+D + H L + P I
Sbjct: 194 TLVLFYTPWCRFSASLAPHFNSLPRAFP---ALHFLALDASQHSSLSTRFGTVAVPNILL 250
Query: 472 F 472
F
Sbjct: 251 F 251
>AF543416-1|AAN34781.1| 172|Homo sapiens thioredoxin-like protein
p19 protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>AF131758-1|AAD20035.1| 172|Homo sapiens Unknown protein.
Length = 172
Score = 36.3 bits (80), Expect = 0.33
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 516 GFGANV-LLAFDDDFEKIISVPTPTIVMFYATWCSHCVTAKPAFSRLATALKTENVPVKA 574
GFG ++ +D ++ + P +V+ + +WC C KP F+ +T + +
Sbjct: 33 GFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAE-STEISELSHNFVM 91
Query: 575 VALEAAENPKAADFA 589
V LE E PK DF+
Sbjct: 92 VNLEDEEEPKDEDFS 106
Score = 35.9 bits (79), Expect = 0.44
Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 289 LVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEP 332
+V+ + WCG CK +KP+F + +T+I N ++ ++ +EP
Sbjct: 58 MVIIHKSWCGACKALKPKFAE-STEISELSHNFVMVNLEDEEEP 100
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 154 KKGPGSHKRSMIMFYAPWCGYCKSMKPDYVEA 185
K+ S M++ + WCG CK++KP + E+
Sbjct: 48 KEAAASGLPLMVIIHKSWCGACKALKPKFAES 79
Score = 32.3 bits (70), Expect = 5.4
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 413 IVMFYAPWCGHCKSTKPEFVKAAE 436
+V+ + WCG CK+ KP+F ++ E
Sbjct: 58 MVIIHKSWCGACKALKPKFAESTE 81
>AF314529-1|AAQ14565.1| 177|Homo sapiens endoplasmic reticulum
DnaJ-PDI fusion protein 2 precursor protein.
Length = 177
Score = 34.7 bits (76), Expect = 1.0
Identities = 15/45 (33%), Positives = 22/45 (48%)
Query: 267 DTDVVHLNGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAA 311
D +++ L FDA + E V FY+P C HC + P + A
Sbjct: 128 DPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA 172
>AF196568-1|AAG28497.1| 330|Homo sapiens thioredoxin-like 2
protein.
Length = 330
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 278 FDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASR 337
++ +L+ +V Y WCG CK + F+K ++ + ++ LA D D+ +
Sbjct: 20 WEEMLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRL---DVLEK 76
Query: 338 FGVKGYPTLKYFNKGE 353
+ K PT ++ GE
Sbjct: 77 YRGKCEPTFLFYAGGE 92
>BC034713-1|AAH34713.1| 78|Homo sapiens DNAJC10 protein protein.
Length = 78
Score = 33.9 bits (74), Expect = 1.8
Identities = 11/39 (28%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 444 VAFGAVDCTLHQDLCANYNVKGYPTIKYFSYFDKAVKDY 482
V G VDC + C ++ YPT+K++ ++++A +++
Sbjct: 6 VKAGKVDCQAYAQTCQKAGIRAYPTVKFY-FYERAKRNF 43
>AL158158-2|CAI14067.1| 85|Homo sapiens thioredoxin protein.
Length = 85
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTE 317
+A+ A + +VV F A WCG CK IKP F A++ + +
Sbjct: 13 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASECEVK 52
Score = 31.9 bits (69), Expect = 7.1
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAF 446
V+ ++S T F+ L +V+ F A WCG CK KP F A + + M F
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASECEVKCMPTF 57
>AF065241-1|AAC17430.1| 84|Homo sapiens thioredoxin delta 3
protein.
Length = 84
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 279 DAILAKAEHALVV-FYAPWCGHCKRIKPEFEKAATKIKTE 317
+A+ A + +VV F A WCG CK IKP F A++ + +
Sbjct: 12 EALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASECEVK 51
Score = 31.9 bits (69), Expect = 7.1
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 394 VRHLDSST-FRNTLRKIKHSIVM--FYAPWCGHCKSTKPEFVKAAEQFADELMVAF 446
V+ ++S T F+ L +V+ F A WCG CK KP F A + + M F
Sbjct: 1 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASECEVKCMPTF 56
>BC107054-1|AAI07055.1| 174|Homo sapiens TXNDC6 protein protein.
Length = 174
Score = 32.3 bits (70), Expect = 5.4
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIK 470
++V Y WCG CK F K E D L A D D+ Y K PT
Sbjct: 8 TVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEAD---RLDVLEKYRGKCEPTFL 64
Query: 471 YFSYFDKAVKD 481
+++ D+A+ D
Sbjct: 65 FYAIKDEALSD 75
>BC036816-1|AAH36816.1| 588|Homo sapiens thioredoxin domain
containing 3 (spermatozoa) protein.
Length = 588
Score = 32.3 bits (70), Expect = 5.4
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++I Y WCG C++M+P + + +L + IL VA+ N Q + P L+
Sbjct: 30 TVIDVYQAWCGPCRAMQPLFRKLKNELNEDEIL-HFAVAEADNIVTLQPFRDKCEPVFLF 88
Query: 223 FERGQFRFPYNGEN 236
G+ G N
Sbjct: 89 SVNGKIIEKIQGAN 102
Score = 31.9 bits (69), Expect = 7.1
Identities = 12/46 (26%), Positives = 23/46 (50%)
Query: 274 NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKI 319
N +D +L ++ Y WCG C+ ++P F K ++ ++I
Sbjct: 16 NQSLWDEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEI 61
>AK094830-1|BAC04430.1| 263|Homo sapiens protein ( Homo sapiens
cDNA FLJ37511 fis, clone BRCAN2000346, weakly similar to
Outer arm dynein intermediate chain 1. ).
Length = 263
Score = 32.3 bits (70), Expect = 5.4
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 412 SIVMFYAPWCGHCKSTKPEFVK-AAEQFADELMVAFGAVDCTLHQDLCANYNVKGYPTIK 470
++V Y WCG CK F K E D L A D D+ Y K PT
Sbjct: 8 TVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEAD---RLDVLEKYRGKCEPTFL 64
Query: 471 YFSYFDKAVKD 481
+++ D+A+ D
Sbjct: 65 FYAIKDEALSD 75
>AF305596-1|AAN04258.1| 588|Homo sapiens sperm-specific thioredoxin
2 protein.
Length = 588
Score = 32.3 bits (70), Expect = 5.4
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++I Y WCG C++M+P + + +L + IL VA+ N Q + P L+
Sbjct: 30 TVIDVYQAWCGPCRAMQPLFRKLKNELNEDEIL-HFAVAEADNIVTLQPFRDKCEPVFLF 88
Query: 223 FERGQFRFPYNGEN 236
G+ G N
Sbjct: 89 SVNGKIIEKIQGAN 102
Score = 31.9 bits (69), Expect = 7.1
Identities = 12/46 (26%), Positives = 23/46 (50%)
Query: 274 NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKI 319
N +D +L ++ Y WCG C+ ++P F K ++ ++I
Sbjct: 16 NQSLWDEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEI 61
>AF202051-1|AAF20909.2| 588|Homo sapiens NM23-H8 protein.
Length = 588
Score = 32.3 bits (70), Expect = 5.4
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 163 SMIMFYAPWCGYCKSMKPDYVEAAGDLKGESILAAIDVAKPGNSKIRQLYNITGFPTLLY 222
++I Y WCG C++M+P + + +L + IL VA+ N Q + P L+
Sbjct: 30 TVIDVYQAWCGPCRAMQPLFRKLKNELNEDEIL-HFAVAEADNIVTLQPFRDKCEPVFLF 88
Query: 223 FERGQFRFPYNGEN 236
G+ G N
Sbjct: 89 SVNGKIIEKIQGAN 102
Score = 31.9 bits (69), Expect = 7.1
Identities = 12/46 (26%), Positives = 23/46 (50%)
Query: 274 NGDSFDAILAKAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKI 319
N +D +L ++ Y WCG C+ ++P F K ++ ++I
Sbjct: 16 NQSLWDEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEI 61
>DQ120656-1|ABB92441.1| 368|Homo sapiens rcADH5 protein.
Length = 368
Score = 31.9 bits (69), Expect = 7.1
Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 8/71 (11%)
Query: 284 KAEHALVVFYAPWCGHCKRIKPEFEKAATKIKTEKINGILAAVDATKEPDLASRFGVKGY 343
KA ++ Y P CG CK KI+ + G++ PD SRF KG
Sbjct: 84 KAGDTVIPLYIPQCGECKFCLYPKTNLCQKIRVTQGKGLM--------PDGTSRFTCKGK 135
Query: 344 PTLKYFNKGEF 354
L+Y F
Sbjct: 136 TILRYMGTSTF 146
>BC047604-1|AAH47604.2| 671|Homo sapiens QSCN6L1 protein protein.
Length = 671
Score = 31.9 bits (69), Expect = 7.1
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 444 VAFGAVDCT--LHQDLCANYNVKGYPTIKYFSYFDKAVKDYTGGQ 486
+ A+DC +Q +C +Y++ YPT +YF F K++T G+
Sbjct: 88 IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAF---TKEFTTGE 129
>BC023532-1|AAH23532.1| 641|Homo sapiens WW domain binding protein
11 protein.
Length = 641
Score = 31.9 bits (69), Expect = 7.1
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 11 ETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKETADTMRG--QA 68
+ KKQ+ V + + +KD K+I+R + + N +++ +V K+ +R +
Sbjct: 32 KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
Query: 69 TLILIDCNNSDNKKLCKKLKVSPE-KPFILKHYKDGDFNKDYDRSESV 115
L L + N D K +KL+V E K L Y D N + ES+
Sbjct: 92 ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESI 139
>BC001621-1|AAH01621.1| 641|Homo sapiens WW domain binding protein
11 protein.
Length = 641
Score = 31.9 bits (69), Expect = 7.1
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 11 ETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKETADTMRG--QA 68
+ KKQ+ V + + +KD K+I+R + + N +++ +V K+ +R +
Sbjct: 32 KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
Query: 69 TLILIDCNNSDNKKLCKKLKVSPE-KPFILKHYKDGDFNKDYDRSESV 115
L L + N D K +KL+V E K L Y D N + ES+
Sbjct: 92 ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESI 139
>AF118023-1|AAD30425.1| 641|Homo sapiens SH3 domain-binding protein
SNP70 protein.
Length = 641
Score = 31.9 bits (69), Expect = 7.1
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 11 ETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKETADTMRG--QA 68
+ KKQ+ V + + +KD K+I+R + + N +++ +V K+ +R +
Sbjct: 32 KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
Query: 69 TLILIDCNNSDNKKLCKKLKVSPE-KPFILKHYKDGDFNKDYDRSESV 115
L L + N D K +KL+V E K L Y D N + ES+
Sbjct: 92 ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESI 139
>AB029309-1|BAA88410.1| 641|Homo sapiens Npw38-binding protein
NpwBP protein.
Length = 641
Score = 31.9 bits (69), Expect = 7.1
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 11 ETKKQKTAVLSDISDIKDFKKILRTKTNVLVLFVNEMKKAHNMVEVFKETADTMRG--QA 68
+ KKQ+ V + + +KD K+I+R + + N +++ +V K+ +R +
Sbjct: 32 KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
Query: 69 TLILIDCNNSDNKKLCKKLKVSPE-KPFILKHYKDGDFNKDYDRSESV 115
L L + N D K +KL+V E K L Y D N + ES+
Sbjct: 92 ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESI 139
>BC093062-1|AAH93062.1| 258|Homo sapiens TXNDC14 protein protein.
Length = 258
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 100 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 158
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 159 GRYTDVSTRYKVSTSPLTK 177
>BC000666-1|AAH00666.1| 296|Homo sapiens thioredoxin domain
containing 14 protein.
Length = 296
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
>AY358501-1|AAQ88865.1| 296|Homo sapiens AVLA237 protein.
Length = 296
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
>AK223058-1|BAD96778.1| 296|Homo sapiens thioredoxin-related
transmembrane protein 2 variant protein.
Length = 296
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
>AK075359-1|BAC11569.1| 372|Homo sapiens protein ( Homo sapiens
cDNA PSEC0045 fis, clone NT2RP1001023. ).
Length = 372
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
>AF132965-1|AAD27740.1| 296|Homo sapiens CGI-31 protein protein.
Length = 296
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
>AF059753-1|AAG43122.1| 372|Homo sapiens My009 protein protein.
Length = 372
Score = 31.5 bits (68), Expect = 9.4
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 394 VRHLDSSTFRNTLRKIKHS--IVMFYAPWCGHCKSTKPEFVKAAEQFADELMVAFGAVDC 451
+++ + T L + K IV F+A W C+S P + + ++ + + FG VD
Sbjct: 138 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 196
Query: 452 TLHQDLCANYNVKGYPTIK 470
+ D+ Y V P K
Sbjct: 197 GRYTDVSTRYKVSTSPLTK 215
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,042,585
Number of Sequences: 224733
Number of extensions: 3663870
Number of successful extensions: 7921
Number of sequences better than 10.0: 175
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 6406
Number of HSP's gapped (non-prelim): 957
length of query: 632
length of database: 73,234,838
effective HSP length: 94
effective length of query: 538
effective length of database: 52,109,936
effective search space: 28035145568
effective search space used: 28035145568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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