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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000659-TA|BGIBMGA000659-PA|IPR013120|Male sterility
C-terminal, IPR004262|Male sterility
         (432 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC017377-1|AAH17377.1|  515|Homo sapiens male sterility domain c...   288   2e-77
AY600449-1|AAT42129.1|  515|Homo sapiens fatty acyl CoA reductas...   288   2e-77
AY423606-1|AAR84086.1|  515|Homo sapiens putative fatty acyl red...   288   2e-77
AY358784-1|AAQ89144.1|  515|Homo sapiens VSIP2423 protein.            288   2e-77
AK026381-1|BAB15467.1|  342|Homo sapiens protein ( Homo sapiens ...   271   3e-72
BC022267-1|AAH22267.1|  515|Homo sapiens male sterility domain c...   265   2e-70
AK027756-1|BAB55347.1|  515|Homo sapiens protein ( Homo sapiens ...   265   2e-70
AK001324-1|BAA91625.1|  515|Homo sapiens protein ( Homo sapiens ...   264   4e-70
AK001927-1|BAA91983.1|  515|Homo sapiens protein ( Homo sapiens ...   262   1e-69
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.       33   2.0  
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.             33   2.0  
X55997-1|CAA39469.1|  373|Homo sapiens 3-beta-hydroxy-5-ene ster...    31   6.0  
X53321-1|CAA37408.1|  373|Homo sapiens Hydroxysteroid dehydrogen...    31   6.0  
U29165-1|AAC51210.1|  826|Homo sapiens MOP1 protein.                   31   6.0  
U22431-1|AAC50152.1|  826|Homo sapiens hypoxia-inducible factor ...    31   6.0  
S45679-1|AAB23543.1|  373|Homo sapiens 3 beta-hydroxysteroid deh...    31   6.0  
M63397-1|AAA51662.1|  373|Homo sapiens 3-beta-hydroxysteroid deh...    31   6.0  
M38180-1|AAA51831.1|  373|Homo sapiens 3-beta-hydroxysteroid deh...    31   6.0  
M35493-1|AAA51538.1|  373|Homo sapiens HSD3B protein.                  31   6.0  
M27137-1|AAA36015.1|  373|Homo sapiens protein ( Human 3 beta-hy...    31   6.0  
BT009776-1|AAP88778.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
BC031999-1|AAH31999.1|  373|Homo sapiens hydroxy-delta-5-steroid...    31   6.0  
BC012527-1|AAH12527.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AL121995-3|CAI23359.1|  375|Homo sapiens hydroxy-delta-5-steroid...    31   6.0  
AF304431-1|AAG43026.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AF208487-1|AAF20149.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AF207602-1|AAF20140.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AF207601-1|AAF20139.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AF050127-1|AAC68568.1|  826|Homo sapiens hypoxia-inducible facto...    31   6.0  
AB073325-1|BAB70608.1|  735|Homo sapiens hypoxia-inducible facto...    31   6.0  
BC132696-1|AAI32697.1|  131|Homo sapiens LOC440905 protein protein.    31   7.9  
BC132694-1|AAI32695.1|  131|Homo sapiens LOC440905 protein protein.    31   7.9  
BC004929-1|AAH04929.1|  369|Homo sapiens hydroxy-delta-5-steroid...    31   7.9  
AK125921-1|BAC86344.1|  131|Homo sapiens .  protein.                   31   7.9  
AK057436-1|BAB71486.1|  196|Homo sapiens protein ( Homo sapiens ...    31   7.9  
AF277719-1|AAG37824.1|  369|Homo sapiens 3 beta-hydroxy-delta 5-...    31   7.9  

>BC017377-1|AAH17377.1|  515|Homo sapiens male sterility domain
           containing 2 protein.
          Length = 515

 Score =  288 bits (707), Expect = 2e-77
 Identities = 140/373 (37%), Positives = 218/373 (58%), Gaps = 2/373 (0%)

Query: 6   SVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRL 65
           S+ ++Y G+N+L+TG TGF+GKVL+EKLL S P++ +VY+L+R K  +T  +R+E++   
Sbjct: 3   SIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSG 62

Query: 66  PLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPLK 125
            LFDRL++E P+   KI AI  ++      LS  + E +     ++FH AAT+R    L+
Sbjct: 63  KLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLR 122

Query: 126 DNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLIE 185
           D V +N   T + I +A+++KNL++F+H+STA+ Y + + + E +Y PP  P+ ++  +E
Sbjct: 123 DAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLE 182

Query: 186 WLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMPG 245
           W+DD  +  +TP L+G  PN Y ++K LAE VV+Q    L + I RPSIV  S+ EP PG
Sbjct: 183 WMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPG 242

Query: 246 WVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLTI 305
           W+DN NGP G+ I AGKG++RT+       A ++PVD             G  + ++  I
Sbjct: 243 WIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRN--I 300

Query: 306 PVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLVP 365
            VYN   G   P  WG+V        ++ PL      PN ++T+N+ L+       H  P
Sbjct: 301 MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP 360

Query: 366 AYCIDFLLFLMGQ 378
           A+  D  L + G+
Sbjct: 361 AFLYDIYLRMTGR 373


>AY600449-1|AAT42129.1|  515|Homo sapiens fatty acyl CoA reductase 1
           protein.
          Length = 515

 Score =  288 bits (707), Expect = 2e-77
 Identities = 140/373 (37%), Positives = 218/373 (58%), Gaps = 2/373 (0%)

Query: 6   SVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRL 65
           S+ ++Y G+N+L+TG TGF+GKVL+EKLL S P++ +VY+L+R K  +T  +R+E++   
Sbjct: 3   SIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSG 62

Query: 66  PLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPLK 125
            LFDRL++E P+   KI AI  ++      LS  + E +     ++FH AAT+R    L+
Sbjct: 63  KLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLR 122

Query: 126 DNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLIE 185
           D V +N   T + I +A+++KNL++F+H+STA+ Y + + + E +Y PP  P+ ++  +E
Sbjct: 123 DAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLE 182

Query: 186 WLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMPG 245
           W+DD  +  +TP L+G  PN Y ++K LAE VV+Q    L + I RPSIV  S+ EP PG
Sbjct: 183 WMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPG 242

Query: 246 WVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLTI 305
           W+DN NGP G+ I AGKG++RT+       A ++PVD             G  + ++  I
Sbjct: 243 WIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRN--I 300

Query: 306 PVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLVP 365
            VYN   G   P  WG+V        ++ PL      PN ++T+N+ L+       H  P
Sbjct: 301 MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP 360

Query: 366 AYCIDFLLFLMGQ 378
           A+  D  L + G+
Sbjct: 361 AFLYDIYLRMTGR 373


>AY423606-1|AAR84086.1|  515|Homo sapiens putative fatty acyl
           reductase protein.
          Length = 515

 Score =  288 bits (707), Expect = 2e-77
 Identities = 140/373 (37%), Positives = 218/373 (58%), Gaps = 2/373 (0%)

Query: 6   SVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRL 65
           S+ ++Y G+N+L+TG TGF+GKVL+EKLL S P++ +VY+L+R K  +T  +R+E++   
Sbjct: 3   SIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSG 62

Query: 66  PLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPLK 125
            LFDRL++E P+   KI AI  ++      LS  + E +     ++FH AAT+R    L+
Sbjct: 63  KLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLR 122

Query: 126 DNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLIE 185
           D V +N   T + I +A+++KNL++F+H+STA+ Y + + + E +Y PP  P+ ++  +E
Sbjct: 123 DAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLE 182

Query: 186 WLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMPG 245
           W+DD  +  +TP L+G  PN Y ++K LAE VV+Q    L + I RPSIV  S+ EP PG
Sbjct: 183 WMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPG 242

Query: 246 WVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLTI 305
           W+DN NGP G+ I AGKG++RT+       A ++PVD             G  + ++  I
Sbjct: 243 WIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRN--I 300

Query: 306 PVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLVP 365
            VYN   G   P  WG+V        ++ PL      PN ++T+N+ L+       H  P
Sbjct: 301 MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP 360

Query: 366 AYCIDFLLFLMGQ 378
           A+  D  L + G+
Sbjct: 361 AFLYDIYLRMTGR 373


>AY358784-1|AAQ89144.1|  515|Homo sapiens VSIP2423 protein.
          Length = 515

 Score =  288 bits (707), Expect = 2e-77
 Identities = 140/373 (37%), Positives = 218/373 (58%), Gaps = 2/373 (0%)

Query: 6   SVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRL 65
           S+ ++Y G+N+L+TG TGF+GKVL+EKLL S P++ +VY+L+R K  +T  +R+E++   
Sbjct: 3   SIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSG 62

Query: 66  PLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPLK 125
            LFDRL++E P+   KI AI  ++      LS  + E +     ++FH AAT+R    L+
Sbjct: 63  KLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLR 122

Query: 126 DNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLIE 185
           D V +N   T + I +A+++KNL++F+H+STA+ Y + + + E +Y PP  P+ ++  +E
Sbjct: 123 DAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLE 182

Query: 186 WLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMPG 245
           W+DD  +  +TP L+G  PN Y ++K LAE VV+Q    L + I RPSIV  S+ EP PG
Sbjct: 183 WMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPG 242

Query: 246 WVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLTI 305
           W+DN NGP G+ I AGKG++RT+       A ++PVD             G  + ++  I
Sbjct: 243 WIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRN--I 300

Query: 306 PVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLVP 365
            VYN   G   P  WG+V        ++ PL      PN ++T+N+ L+       H  P
Sbjct: 301 MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP 360

Query: 366 AYCIDFLLFLMGQ 378
           A+  D  L + G+
Sbjct: 361 AFLYDIYLRMTGR 373


>AK026381-1|BAB15467.1|  342|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ22728 fis, clone HSI15617. ).
          Length = 342

 Score =  271 bits (665), Expect = 3e-72
 Identities = 127/318 (39%), Positives = 195/318 (61%), Gaps = 2/318 (0%)

Query: 6   SVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRL 65
           S+ ++Y G+N+L+TG TGF+GKVL+EKLL S P++ +VY+L+R K  +T  +R+E++   
Sbjct: 3   SIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSG 62

Query: 66  PLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPLK 125
            LFDRL++E P+   KI AI  ++      LS  + E +     ++FH AAT+R    L+
Sbjct: 63  KLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLR 122

Query: 126 DNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLIE 185
           D V +N   T + I +A+++KNL++F+H+STA+ Y + + + E +Y PP  P+ ++  +E
Sbjct: 123 DAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLE 182

Query: 186 WLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMPG 245
           W+DD  +  +TP L+G  PN Y ++K LAE VV+Q    L + I RPSIV  S+ EP PG
Sbjct: 183 WMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPG 242

Query: 246 WVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLTI 305
           W+DN NGP G+ I AGKG++RT+       A ++PVD             G  + ++  I
Sbjct: 243 WIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRN--I 300

Query: 306 PVYNVNIGHQKPMTWGDV 323
            VYN   G   P  WG+V
Sbjct: 301 MVYNCTTGSTNPFHWGEV 318


>BC022267-1|AAH22267.1|  515|Homo sapiens male sterility domain
           containing 1 protein.
          Length = 515

 Score =  265 bits (650), Expect = 2e-70
 Identities = 134/375 (35%), Positives = 209/375 (55%), Gaps = 2/375 (0%)

Query: 5   TSVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQR 64
           +++  FY G++IL+TG TGF+GKVL+EKL  + P++  +YIL+RPK  +T+ QR+  +  
Sbjct: 2   STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILD 61

Query: 65  LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPL 124
             LF+++K   PN   KI+AI  D+   DF +S  +++ L     ++FH AAT+R +  L
Sbjct: 62  SKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTL 121

Query: 125 KDNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLI 184
           +  V +N + T + + +A ++  L+ F+H+STA+   + + + E +Y  P +P+ ++  +
Sbjct: 122 RHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSL 181

Query: 185 EWLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMP 244
           EWLDD  +  +TP L+   PN YT++K L E VV+Q  ++L I I RPSIV  ++ EP P
Sbjct: 182 EWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFP 241

Query: 245 GWVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLT 304
           GWVDN+NGP G++I  GKG +R +       A VIPVD         G      + KS  
Sbjct: 242 GWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTL 301

Query: 305 IPVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLV 364
             VY++  G+  P  W  +         K P   P   PN + T+N    +      H  
Sbjct: 302 --VYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRA 359

Query: 365 PAYCIDFLLFLMGQK 379
           PA   D  L L G+K
Sbjct: 360 PAIIYDCYLRLTGRK 374


>AK027756-1|BAB55347.1|  515|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14850 fis, clone PLACE1000636, weakly similar to
           MALE STERILITY PROTEIN 2. ).
          Length = 515

 Score =  265 bits (650), Expect = 2e-70
 Identities = 134/375 (35%), Positives = 209/375 (55%), Gaps = 2/375 (0%)

Query: 5   TSVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQR 64
           +++  FY G++IL+TG TGF+GKVL+EKL  + P++  +YIL+RPK  +T+ QR+  +  
Sbjct: 2   STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILD 61

Query: 65  LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPL 124
             LF+++K   PN   KI+AI  D+   DF +S  +++ L     ++FH AAT+R +  L
Sbjct: 62  SKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTL 121

Query: 125 KDNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLI 184
           +  V +N + T + + +A ++  L+ F+H+STA+   + + + E +Y  P +P+ ++  +
Sbjct: 122 RHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSL 181

Query: 185 EWLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMP 244
           EWLDD  +  +TP L+   PN YT++K L E VV+Q  ++L I I RPSIV  ++ EP P
Sbjct: 182 EWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFP 241

Query: 245 GWVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLT 304
           GWVDN+NGP G++I  GKG +R +       A VIPVD         G      + KS  
Sbjct: 242 GWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTL 301

Query: 305 IPVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLV 364
             VY++  G+  P  W  +         K P   P   PN + T+N    +      H  
Sbjct: 302 --VYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRA 359

Query: 365 PAYCIDFLLFLMGQK 379
           PA   D  L L G+K
Sbjct: 360 PAIIYDCYLRLTGRK 374


>AK001324-1|BAA91625.1|  515|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10462 fis, clone NT2RP1001494, weakly similar to
           MALE STERILITY PROTEIN 2. ).
          Length = 515

 Score =  264 bits (647), Expect = 4e-70
 Identities = 134/375 (35%), Positives = 208/375 (55%), Gaps = 2/375 (0%)

Query: 5   TSVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQR 64
           +++  FY G++IL+TG TGF+GKVL+EKL  + P++  +YIL+RPK  +T+ QR+  +  
Sbjct: 2   STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILD 61

Query: 65  LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPL 124
             LF+++K   PN   KI+AI  D+   DF +S  +++ L     ++FH AAT+R +  L
Sbjct: 62  SKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTL 121

Query: 125 KDNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLI 184
           +  V +N + T + + +A ++  L+ F+H+STA+   + + + E  Y  P +P+ ++  +
Sbjct: 122 RHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVTYPCPVEPKKIIDSL 181

Query: 185 EWLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMP 244
           EWLDD  +  +TP L+   PN YT++K L E VV+Q  ++L I I RPSIV  ++ EP P
Sbjct: 182 EWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFP 241

Query: 245 GWVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLT 304
           GWVDN+NGP G++I  GKG +R +       A VIPVD         G      + KS  
Sbjct: 242 GWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTL 301

Query: 305 IPVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLV 364
             VY++  G+  P  W  +         K P   P   PN + T+N    +      H  
Sbjct: 302 --VYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRA 359

Query: 365 PAYCIDFLLFLMGQK 379
           PA   D  L L G+K
Sbjct: 360 PAIIYDCYLRLTGRK 374


>AK001927-1|BAA91983.1|  515|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11065 fis, clone PLACE1004868, weakly similar to
           MALE STERILITY PROTEIN 2. ).
          Length = 515

 Score =  262 bits (643), Expect = 1e-69
 Identities = 133/375 (35%), Positives = 208/375 (55%), Gaps = 2/375 (0%)

Query: 5   TSVRDFYAGRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQR 64
           +++  FY G++IL+TG TGF+GKVL+EKL  + P++  +YIL+RPK  +T+ Q +  +  
Sbjct: 2   STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQGVFQILD 61

Query: 65  LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRLEAPL 124
             LF+++K   PN   KI+AI  D+   DF +S  +++ L     ++FH AAT+R +  L
Sbjct: 62  SKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTL 121

Query: 125 KDNVNMNTSGTLRTIKVAKKLKNLQIFVHLSTAFCYPDYEVLGEKLYAPPAKPEHVMRLI 184
           +  V +N + T + + +A ++  L+ F+H+STA+   + + + E +Y  P +P+ ++  +
Sbjct: 122 RHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSL 181

Query: 185 EWLDDRQLTLLTPSLLGPHPNCYTFSKRLAENVVEQAYKDLPIVIARPSIVCPSYSEPMP 244
           EWLDD  +  +TP L+   PN YT++K L E VV+Q  ++L I I RPSIV  ++ EP P
Sbjct: 182 EWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFP 241

Query: 245 GWVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDXXXXXXXXXGMIEGTKKEKSLT 304
           GWVDN+NGP G++I  GKG +R +       A VIPVD         G      + KS  
Sbjct: 242 GWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTL 301

Query: 305 IPVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLV 364
             VY++  G+  P  W  +         K P   P   PN + T+N    +      H  
Sbjct: 302 --VYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRA 359

Query: 365 PAYCIDFLLFLMGQK 379
           PA   D  L L G+K
Sbjct: 360 PAIIYDCYLRLTGRK 374


>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
          Length = 2479

 Score = 33.1 bits (72), Expect = 2.0
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 57   QRLEDLQR-LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSN-LEI--ENLSKEVTVVF 112
            QR  DL+R L +FDR +NE  NA  K +   G +      L N LEI    + + + ++ 
Sbjct: 1409 QREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIIL 1468

Query: 113  HFAATLR-LEAPLKD 126
               AT + LE  LK+
Sbjct: 1469 ETRATCKSLEEKLKE 1483


>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
          Length = 1540

 Score = 33.1 bits (72), Expect = 2.0
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 57  QRLEDLQR-LPLFDRLKNERPNALNKIKAIQGDVLFEDFGLSN-LEI--ENLSKEVTVVF 112
           QR  DL+R L +FDR +NE  NA  K +   G +      L N LEI    + + + ++ 
Sbjct: 470 QREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIIL 529

Query: 113 HFAATLR-LEAPLKD 126
              AT + LE  LK+
Sbjct: 530 ETRATCKSLEEKLKE 544


>X55997-1|CAA39469.1|  373|Homo sapiens 3-beta-hydroxy-5-ene steroid
            dehydrogenase protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>X53321-1|CAA37408.1|  373|Homo sapiens Hydroxysteroid dehydrogenase
           / Delta (5)->(4) Isomerase protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>U29165-1|AAC51210.1|  826|Homo sapiens MOP1 protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>U22431-1|AAC50152.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>S45679-1|AAB23543.1|  373|Homo sapiens 3 beta-hydroxysteroid
           dehydrogenase/delta 5-delta 4 isomerase protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>M63397-1|AAA51662.1|  373|Homo sapiens 3-beta-hydroxysteroid
           dehydrogenase/delta-5-4-isomerase protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>M38180-1|AAA51831.1|  373|Homo sapiens 3-beta-hydroxysteroid
           dehydrogenase/delta-5-delta-4-isomerase protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>M35493-1|AAA51538.1|  373|Homo sapiens HSD3B protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>M27137-1|AAA36015.1|  373|Homo sapiens protein ( Human 3
           beta-hydroxy-5-ene steroid dehydrogenase mRNA, complete
           cds. ).
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>BT009776-1|AAP88778.1|  826|Homo sapiens hypoxia-inducible factor
           1, alpha subunit (basic helix-loop-helix transcription
           protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>BC031999-1|AAH31999.1|  373|Homo sapiens hydroxy-delta-5-steroid
           dehydrogenase, 3 beta- and steroid delta-isomerase 1
           protein.
          Length = 373

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 3   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 51

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 52  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 100

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 101 NVKGTQLLLEACVQ-ASVPVFIYTSS 125


>BC012527-1|AAH12527.1|  826|Homo sapiens hypoxia-inducible factor
           1, alpha subunit (basic helix-loop-helix transcription
           protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AL121995-3|CAI23359.1|  375|Homo sapiens hydroxy-delta-5-steroid
           dehydrogenase, 3 beta-andotein 2 protein.
          Length = 375

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 25/146 (17%)

Query: 13  GRNILVTGGTGFMGKVLVEKLLYSVPEIGNVYILMRPKKAKTVAQRLEDLQRLPLFDRLK 72
           G + LVTG  GF+G+ ++ +LL    E+  + +L    KA     R E       F +L+
Sbjct: 5   GWSCLVTGAGGFLGQRII-RLLVKEKELKEIRVL---DKAFGPELREE-------FSKLQ 53

Query: 73  NERPNALNKIKAIQGDVLFEDFGLSNLEIENLSKEVTVVFHFAATLRL--EAPLKDNVNM 130
           N+      K+  ++GD+L E F      ++   ++V+V+ H A  + +      +  +N+
Sbjct: 54  NK-----TKLTVLEGDILDEPF------LKRACQDVSVIIHTACIIDVFGVTHRESIMNV 102

Query: 131 NTSGTLRTIKVAKKLKNLQIFVHLST 156
           N  GT   ++   +  ++ +F++ S+
Sbjct: 103 NVKGTQLLLEACVQ-ASVPVFIYTSS 127


>AF304431-1|AAG43026.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha subunit protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AF208487-1|AAF20149.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AF207602-1|AAF20140.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AF207601-1|AAF20139.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AF050127-1|AAC68568.1|  826|Homo sapiens hypoxia-inducible factor 1
           alpha subunit protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>AB073325-1|BAB70608.1|  735|Homo sapiens hypoxia-inducible factor 1
           alpha variant protein.
          Length = 735

 Score = 31.5 bits (68), Expect = 6.0
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 58  RLEDLQRLPLFDRLKNERPNALNKIKAIQGDVLFE-DFGLSNLEIENLSKEVTVVFHFAA 116
           ++E      LFD+LK E P+AL  +    GD +   DFG ++ E ++   E   +++   
Sbjct: 377 KVESEDTSSLFDKLKKE-PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYN--- 432

Query: 117 TLRLEAPLKDNVNMNTS-GTLRTIKVAKKLKN 147
            + L +P +   N+N +   L T +  K L++
Sbjct: 433 DVMLPSPNEKLQNINLAMSPLPTAETPKPLRS 464


>BC132696-1|AAI32697.1|  131|Homo sapiens LOC440905 protein protein.
          Length = 131

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)

Query: 298 KKEKSLTIPVYNVNIGHQKPMTWGDV-LTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEI 356
           KK++  ++ VY+   G+  P   G +   V   +    P    L  P  D TT+    + 
Sbjct: 29  KKKQPKSVLVYHCTSGNLNPCNRGKMGFQVLATFEIPIPFERALTRPYADFTTSNFRTQY 88

Query: 357 RRIFYHLVPAYCIDFLLFLMGQK 379
                   PA   DF L+L G+K
Sbjct: 89  WNAISQQAPAIIYDFYLWLTGRK 111


>BC132694-1|AAI32695.1|  131|Homo sapiens LOC440905 protein protein.
          Length = 131

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)

Query: 298 KKEKSLTIPVYNVNIGHQKPMTWGDV-LTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEI 356
           KK++  ++ VY+   G+  P   G +   V   +    P    L  P  D TT+    + 
Sbjct: 29  KKKQPKSVLVYHCTSGNLNPCNRGKMGFQVLATFEIPIPFERALTRPYADFTTSNFRTQY 88

Query: 357 RRIFYHLVPAYCIDFLLFLMGQK 379
                   PA   DF L+L G+K
Sbjct: 89  WNAISQQAPAIIYDFYLWLTGRK 111


>BC004929-1|AAH04929.1|  369|Homo sapiens hydroxy-delta-5-steroid
          dehydrogenase, 3 beta- and steroid delta-isomerase 7
          protein.
          Length = 369

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 13/29 (44%), Positives = 19/29 (65%)

Query: 17 LVTGGTGFMGKVLVEKLLYSVPEIGNVYI 45
          LVTGG GF+G+ +V  LL   P +G + +
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRV 41


>AK125921-1|BAC86344.1|  131|Homo sapiens .  protein.
          Length = 131

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)

Query: 298 KKEKSLTIPVYNVNIGHQKPMTWGDV-LTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEI 356
           KK++  ++ VY+   G+  P   G +   V   +    P    L  P  D TT+    + 
Sbjct: 29  KKKQPKSVLVYHCTSGNLNPCNRGKMGFQVLATFEIPIPFERALTRPYADFTTSNFRTQY 88

Query: 357 RRIFYHLVPAYCIDFLLFLMGQK 379
                   PA   DF L+L G+K
Sbjct: 89  WNAISQQAPAIIYDFYLWLTGRK 111


>AK057436-1|BAB71486.1|  196|Homo sapiens protein ( Homo sapiens
          cDNA FLJ32874 fis, clone TESTI2004000, highly similar
          to Rattus norvegicus cca2 mRNA. ).
          Length = 196

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 13/29 (44%), Positives = 19/29 (65%)

Query: 17 LVTGGTGFMGKVLVEKLLYSVPEIGNVYI 45
          LVTGG GF+G+ +V  LL   P +G + +
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRV 41


>AF277719-1|AAG37824.1|  369|Homo sapiens 3 beta-hydroxy-delta
          5-C27-steroid oxidoreductase protein.
          Length = 369

 Score = 31.1 bits (67), Expect = 7.9
 Identities = 13/29 (44%), Positives = 19/29 (65%)

Query: 17 LVTGGTGFMGKVLVEKLLYSVPEIGNVYI 45
          LVTGG GF+G+ +V  LL   P +G + +
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRV 41


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.323    0.140    0.432 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 65,027,528
Number of Sequences: 224733
Number of extensions: 2752997
Number of successful extensions: 7418
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 7393
Number of HSP's gapped (non-prelim): 36
length of query: 432
length of database: 73,234,838
effective HSP length: 92
effective length of query: 340
effective length of database: 52,559,402
effective search space: 17870196680
effective search space used: 17870196680
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)

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