Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000642-TA|BGIBMGA000642-PA|IPR005963|Tyrosine
5-monooxygenase, IPR002912|Amino acid-binding ACT, IPR001273|Aromatic
amino acid hydroxylase
(502 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep: CG91... 751 0.0
UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135; Meta... 567 e-160
UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|R... 464 e-129
UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30; Euka... 461 e-128
UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3; Caenorhabd... 446 e-124
UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona inte... 419 e-116
UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61; Coeloma... 402 e-110
UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28; Deutero... 398 e-109
UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;... 397 e-109
UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15; Endopte... 377 e-103
UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome s... 360 5e-98
UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia japo... 351 3e-95
UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistos... 324 2e-87
UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona in... 311 2e-83
UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n... 301 4e-80
UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3; Caenorha... 295 2e-78
UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, wh... 254 4e-66
UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid... 249 2e-64
UniRef50_Q4THP6 Cluster: Chromosome undetermined SCAF2776, whole... 222 2e-56
UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=... 186 9e-46
UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3; Actinomy... 178 2e-43
UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan... 169 2e-40
UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1; Salini... 142 2e-32
UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1; Aci... 135 2e-30
UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4; Legio... 134 4e-30
UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8; Prote... 134 5e-30
UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1; Ricke... 130 6e-29
UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40; Prot... 130 8e-29
UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1; Morit... 120 7e-26
UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=... 120 1e-25
UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66; Gamm... 119 2e-25
UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 117 6e-25
UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2; Alpha... 117 8e-25
UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3; C... 114 4e-24
UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 109 1e-22
UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 109 2e-22
UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 107 7e-22
UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19; Vibr... 107 7e-22
UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1; Mesor... 107 7e-22
UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1; Hypho... 107 9e-22
UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1; Ocean... 103 1e-20
UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna... 103 1e-20
UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1; S... 102 2e-20
UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4; Sphin... 99 2e-19
UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyc... 86 2e-15
UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1; Cytop... 74 1e-11
UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase biopteri... 73 2e-11
UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1; ... 72 4e-11
UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylas... 72 4e-11
UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09
UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5; C... 61 6e-08
UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13; Ba... 61 8e-08
UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1; E... 60 1e-07
UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative; ... 56 3e-06
UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1; Bac... 55 4e-06
UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1; Pedob... 54 1e-05
UniRef50_O67085 Cluster: P-protein [Includes: Chorismate mutase ... 48 8e-04
UniRef50_Q751Q3 Cluster: AGL364Cp; n=1; Eremothecium gossypii|Re... 44 0.007
UniRef50_Q8RB13 Cluster: Prephenate dehydratase; n=3; Thermoanae... 42 0.038
UniRef50_Q58054 Cluster: Prephenate dehydratase; n=26; Euryarcha... 40 0.12
UniRef50_UPI00003C844A Cluster: hypothetical protein Faci_030002... 40 0.15
UniRef50_P96240 Cluster: POSSIBLE PREPHENATE DEHYDRATASE PHEA; n... 39 0.27
UniRef50_Q6PBJ4 Cluster: Zgc:73377; n=2; Danio rerio|Rep: Zgc:73... 39 0.35
UniRef50_Q3AMU0 Cluster: Prephenate dehydratase; n=21; Cyanobact... 39 0.35
UniRef50_Q1AWL9 Cluster: Prephenate dehydratase; n=1; Rubrobacte... 39 0.35
UniRef50_Q0AYS3 Cluster: Prephenate dehydratase; n=1; Syntrophom... 39 0.35
UniRef50_A1VGC5 Cluster: Chorismate mutase; n=4; Deltaproteobact... 39 0.35
UniRef50_Q8KBW6 Cluster: Prephenate dehydratase; n=8; Chlorobiac... 38 0.47
UniRef50_A6DR92 Cluster: Chorismate mutase/prephenate dehydratas... 38 0.47
UniRef50_UPI00015BC788 Cluster: UPI00015BC788 related cluster; n... 38 0.62
UniRef50_Q0AQ04 Cluster: Prephenate dehydratase; n=1; Maricaulis... 38 0.62
UniRef50_A6G281 Cluster: Chorismate mutase/prephenate dehydratas... 38 0.62
UniRef50_Q8TZ60 Cluster: Prephenate dehydratase; n=1; Methanopyr... 38 0.62
UniRef50_Q2FQ53 Cluster: Prephenate dehydratase; n=2; Methanomic... 38 0.62
UniRef50_Q187E6 Cluster: P-protein [includes: chorismate mutase ... 38 0.82
UniRef50_A0UXB4 Cluster: Prephenate dehydratase; n=2; Clostridiu... 38 0.82
UniRef50_P10341 Cluster: Prephenate dehydratase; n=4; Corynebact... 38 0.82
UniRef50_Q1GS18 Cluster: Threonine dehydratase; n=19; Proteobact... 37 1.1
UniRef50_Q6L0A4 Cluster: Prephenate dehydratase; n=1; Picrophilu... 37 1.1
UniRef50_A2SR16 Cluster: Prephenate dehydratase; n=2; Methanomic... 37 1.1
UniRef50_Q9WY02 Cluster: Chorismate mutase/prephenate dehydratas... 37 1.4
UniRef50_A3EWC2 Cluster: Prephenate dehydratase; n=1; Leptospiri... 37 1.4
UniRef50_A6NXG7 Cluster: Putative uncharacterized protein; n=1; ... 36 1.9
UniRef50_P73081 Cluster: Sll1939 protein; n=1; Synechocystis sp.... 36 2.5
UniRef50_Q115I4 Cluster: TonB family protein; n=1; Trichodesmium... 36 2.5
UniRef50_Q14246-2 Cluster: Isoform 2 of Q14246 ; n=3; Homo/Pan/G... 36 3.3
UniRef50_Q5NLV8 Cluster: Prephenate dehydratase; n=8; Sphingomon... 36 3.3
UniRef50_Q3ZZI7 Cluster: Chorismate mutase/prephenate dehydratas... 36 3.3
UniRef50_Q13H21 Cluster: Putative FAD dependent oxidoreductase; ... 36 3.3
UniRef50_Q8RUZ5 Cluster: Putative uncharacterized protein At2g40... 36 3.3
UniRef50_Q4Q710 Cluster: Putative uncharacterized protein; n=3; ... 36 3.3
UniRef50_Q6FPZ7 Cluster: Similar to sp|P53278 Saccharomyces cere... 36 3.3
UniRef50_O30012 Cluster: Chorismate mutase/prephenate dehydratas... 36 3.3
UniRef50_Q14246 Cluster: EGF-like module-containing mucin-like h... 36 3.3
UniRef50_Q27R78 Cluster: Pol protein; n=3; Human immunodeficienc... 35 4.4
UniRef50_A4XJH7 Cluster: Prephenate dehydratase; n=1; Caldicellu... 35 4.4
UniRef50_Q97AD5 Cluster: Prephenate dehydratase; n=1; Thermoplas... 35 5.8
UniRef50_A0L410 Cluster: Chorismate mutase; n=1; Magnetococcus s... 34 7.6
>UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep:
CG9122-PA - Drosophila melanogaster (Fruit fly)
Length = 555
Score = 751 bits (1857), Expect = 0.0
Identities = 348/453 (76%), Positives = 394/453 (86%), Gaps = 1/453 (0%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQ 106
ERIS++FTL+NQVG L RAL VFQ+LGINVLH+E + AD+LVDVECD +R++Q
Sbjct: 77 ERISIIFTLRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRRLDQ 136
Query: 107 LKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEMPWFPRKISDLDRAQNVLMYG 166
+ +ML REV T P+ +SA +SFDFG+M WFPRKISDLD+AQNVLMYG
Sbjct: 137 VVKMLNREVASVNYTSVNTQGLARAPS-LSACSSFDFGDMVWFPRKISDLDKAQNVLMYG 195
Query: 167 SELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQ 226
SELDADHPGFKDP+YRKRREQF+AIANN+K+G+PIP+VQYT E+KTWG VF ELH+LY
Sbjct: 196 SELDADHPGFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYV 255
Query: 227 KHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLA 286
HA PEY++NWP+L KYCGYREDN+PQL+DVS +LKRKTGFQLRPVAGYLSPRDFLSGLA
Sbjct: 256 LHAVPEYMDNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLA 315
Query: 287 FRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDADID 346
FRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN SFAQFSQE+GLASLGASDADI+
Sbjct: 316 FRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIE 375
Query: 347 KLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECI 406
KLATLYFFTVEFGLC+Q D +F VYGAGLLSSVAELQHA+T KIK+FDP++T +ECI
Sbjct: 376 KLATLYFFTVEFGLCKQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECI 435
Query: 407 ITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQKITALVSELR 466
ITSYQNAYYYTDSFEEAKE+MRAFAESIQRPFGVRYNPYT SVEVLSNA+KITA+VSELR
Sbjct: 436 ITSYQNAYYYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELR 495
Query: 467 GDLCIVSSAIKKISAQDSTLDVESIANMLHTGL 499
GDL IV SA++KISA D LDV+SIANMLH L
Sbjct: 496 GDLSIVCSALRKISATDENLDVDSIANMLHNSL 528
>UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135;
Metazoa|Rep: Tryptophan 5-hydroxylase 2 - Homo sapiens
(Human)
Length = 490
Score = 567 bits (1400), Expect = e-160
Identities = 268/465 (57%), Positives = 341/465 (73%), Gaps = 12/465 (2%)
Query: 17 GSDWQVKNESPHHPKLGELHAARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINV 76
GS K S + G +++ +A ES + +V+F+LKN+VGGLV+AL +FQ+ +N+
Sbjct: 32 GSSTLNKPNSGKNDDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNM 91
Query: 77 LHIESRKSMTEVSSADILVDVECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMS 136
+HIESRKS S +I VD EC +L ++LK + + PP+
Sbjct: 92 VHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPEN----------I 141
Query: 137 AAASFDFGEMPWFPRKISDLDRAQN-VLMYGSELDADHPGFKDPIYRKRREQFAAIANNY 195
+ ++PWFPRKIS+LD+ + VLMYGSELDADHPGFKD +YR+RR+ F +A Y
Sbjct: 142 WTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGY 201
Query: 196 KYGHPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLE 255
KYG PIP+V+YTE E KTWG+VFREL KLY HAC EYL+N+P L KYCGYREDN+PQLE
Sbjct: 202 KYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLE 261
Query: 256 DVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELL 315
DVS FLK ++GF +RPVAGYLSPRDFL+GLA+RVFHCTQYIRH SDP YTPEPD CHELL
Sbjct: 262 DVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELL 321
Query: 316 GHMPLLANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGL 375
GH+PLLA+P FAQFSQE+GLASLGASD D+ KLAT YFFT+EFGLC+Q +G YGAGL
Sbjct: 322 GHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQ-EGQLRAYGAGL 380
Query: 376 LSSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQ 435
LSS+ EL+HAL+ +K FDP T +EC+IT++Q AY+ ++SFEEAKEKMR FA+SI
Sbjct: 381 LSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSIT 440
Query: 436 RPFGVRYNPYTQSVEVLSNAQKITALVSELRGDLCIVSSAIKKIS 480
RPF V +NPYTQS+E+L + + I +V +LR DL V A+ K++
Sbjct: 441 RPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMN 485
>UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|Rep:
SJCHGC01235 protein - Schistosoma japonicum (Blood
fluke)
Length = 497
Score = 464 bits (1143), Expect = e-129
Identities = 232/457 (50%), Positives = 305/457 (66%), Gaps = 14/457 (3%)
Query: 36 HAARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSS----- 90
H Q + I+ + +L N + + +++F D GIN+ HIESR + V
Sbjct: 24 HFCSAQTNQSLQEITFIISLVNNMNDMKSLINIFTDRGINIRHIESRIKKSNVEKDIKSL 83
Query: 91 ----ADILVDVECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEM 146
++L+ V+ + E+L LK + +V T + + S +F G +
Sbjct: 84 QFQPLELLIYVKFPFREYEKLSEELK-SFSSYHIVH-STLESLVSHSVKSKNLTFK-GGV 140
Query: 147 PWFPRKISDLDR-AQNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQ 205
PWFPR ISDLD + +VLMYG ELDADHPGFKD YR+RR FA IA YK+G IP +
Sbjct: 141 PWFPRHISDLDEVSHHVLMYGKELDADHPGFKDEEYRRRRMMFADIAFTYKWGQQIPFID 200
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YTETE TWG V+REL +LY+ AC E+ +N L GY E +LPQL+ VS FLK +T
Sbjct: 201 YTETEKMTWGCVYRELTRLYKTTACREFQKNLALLQDEAGYNEFDLPQLQVVSDFLKART 260
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
GF LRPVAGYLS RDFLSGLAFRVF+CTQYIRH DPFYTPEPDCCHELLGH+P+LA+P
Sbjct: 261 GFCLRPVAGYLSARDFLSGLAFRVFYCTQYIRHQGDPFYTPEPDCCHELLGHVPMLADPK 320
Query: 326 FAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHA 385
FA+FSQE+GLASLG SD +I KL+T YFFT+EFGLCRQ + YGAGLLSSVAELQ+A
Sbjct: 321 FARFSQEIGLASLGTSDDEIKKLSTCYFFTIEFGLCRQ-ENQLRAYGAGLLSSVAELQYA 379
Query: 386 LTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPY 445
L+ IK F P ++EEC++T++QN Y+ T SFE+A KMR F +I+RPF VRYNPY
Sbjct: 380 LSDKAVIKPFIPMEVINEECLVTTFQNGYFETSSFEDATHKMREFVRTIRRPFDVRYNPY 439
Query: 446 TQSVEVLSNAQKITALVSELRGDLCIVSSAIKKISAQ 482
TQS+E++ + + L+ +L+ +L ++ ++ K+S +
Sbjct: 440 TQSIEIIESPGSVANLIQDLQFELTTINESLLKMSKE 476
>UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30;
Eukaryota|Rep: Phenylalanine-4-hydroxylase - Homo
sapiens (Human)
Length = 452
Score = 461 bits (1137), Expect = e-128
Identities = 227/432 (52%), Positives = 293/432 (67%), Gaps = 16/432 (3%)
Query: 49 ISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQLK 108
IS++F+LK +VG L + L +F++ +N+ HIESR S + + + D + + L
Sbjct: 35 ISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHL--DKRSLPALT 92
Query: 109 RMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEMPWFPRKISDLDR-AQNVLMYGS 167
++K D + + T +PWFPR I +LDR A +L YG+
Sbjct: 93 NIIKILRHDIGATVHELSRDKKKDT------------VPWFPRTIQELDRFANQILSYGA 140
Query: 168 ELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQK 227
ELDADHPGFKDP+YR RR+QFA IA NY++G PIP+V+Y E E KTWG VF+ L LY+
Sbjct: 141 ELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKT 200
Query: 228 HACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAF 287
HAC EY +P L KYCG+ EDN+PQLEDVS FL+ TGF+LRPVAG LS RDFL GLAF
Sbjct: 201 HACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAF 260
Query: 288 RVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDADIDK 347
RVFHCTQYIRH S P YTPEPD CHELLGH+PL ++ SFAQFSQE+GLASLGA D I+K
Sbjct: 261 RVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEK 320
Query: 348 LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECII 407
LAT+Y+FTVEFGLC+Q D S YGAGLLSS ELQ+ L+ K+ + + T + +
Sbjct: 321 LATIYWFTVEFGLCKQGD-SIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTV 379
Query: 408 TSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQKITALVSELRG 467
T +Q YY +SF +AKEK+R FA +I RPF VRY+PYTQ +EVL N Q++ L +
Sbjct: 380 TEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINS 439
Query: 468 DLCIVSSAIKKI 479
++ I+ SA++KI
Sbjct: 440 EIGILCSALQKI 451
>UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3;
Caenorhabditis|Rep: Tryptophan hydroxylase -
Caenorhabditis elegans
Length = 532
Score = 446 bits (1100), Expect = e-124
Identities = 219/423 (51%), Positives = 298/423 (70%), Gaps = 24/423 (5%)
Query: 76 VLHIESRKSMTEVSSA-DILVDVEC---DPQRMEQLKRMLKREVQDFE--VVPPQTGDEF 129
+ H+E+R S S D+L+++E Q L R+ +V + + P +++
Sbjct: 114 IKHLETRDSQDGSSKTMDVLLEIELFHYGKQEAMDLMRLNGLDVHEVSSTIRPTAIKEQY 173
Query: 130 PPPTPMSAAASFDFGEMPWFPRKISDLDR-AQNVLMYGSELDADHPGFKDPIYRKRREQF 188
P A + WFP+ I DLD A+ V+MYG+ LDADHPGFKD YR+RR F
Sbjct: 174 TEPGSDDATTGSE-----WFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMF 228
Query: 189 AAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYRE 248
A +A NYK+G PIP+ +YT +E KTWGI++R+L +L++KHAC ++L+N+ L ++CGY E
Sbjct: 229 AELALNYKHGEPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSE 288
Query: 249 DNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEP 308
+N+PQLED+ FLK KTGF++RPVAGYLS RDFL+GLA+RVF CTQY+RH +DPFYTPEP
Sbjct: 289 NNIPQLEDICKFLKAKTGFRVRPVAGYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEP 348
Query: 309 DCCHELLGHMPLLANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCR------ 362
D HEL+GHM L A+P FAQFSQE+GLASLGAS+ D+ KLATLYFF++EFGL
Sbjct: 349 DTVHELMGHMALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLSSDDAADS 408
Query: 363 --QPDGS----FCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYY 416
+ +GS F VYGAGLLSS ELQHA+ I RFDPD V +EC+IT++Q+AY+Y
Sbjct: 409 PVKENGSNHERFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITTFQSAYFY 468
Query: 417 TDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQKITALVSELRGDLCIVSSAI 476
T +FEEA++K+R F +++RPF VRYNPYT+SVEVL+N++ I V+ LR D+ +++ A+
Sbjct: 469 TRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGAL 528
Query: 477 KKI 479
I
Sbjct: 529 HYI 531
>UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona
intestinalis|Rep: Tryptophan hydroxylase - Ciona
intestinalis (Transparent sea squirt)
Length = 448
Score = 419 bits (1032), Expect = e-116
Identities = 186/330 (56%), Positives = 257/330 (77%), Gaps = 2/330 (0%)
Query: 148 WFPRKISDLDR-AQNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQY 206
WFP+ ++DLD A+NVLMYG+ELDADHPGFKD +YRKRR+ F +A ++++G IP+V+Y
Sbjct: 109 WFPKCLADLDGCAKNVLMYGAELDADHPGFKDEVYRKRRDYFTKLAMDFRHGDKIPRVEY 168
Query: 207 TETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTG 266
T+ EI+TWG V++EL +L+ AC ++L+N P L ++C EDN+PQLED+S+FL+ +TG
Sbjct: 169 TKIEIETWGKVYKELMELHPTRACAQHLKNLPLLSEFCKCSEDNVPQLEDISAFLQSRTG 228
Query: 267 FQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSF 326
F++RP AG+LSPRDFL+GLAFRVF+CTQYIRH SDP+YTPEPD CHE+LGH+PLLA+P F
Sbjct: 229 FRIRPAAGFLSPRDFLAGLAFRVFNCTQYIRHHSDPYYTPEPDICHEILGHVPLLADPEF 288
Query: 327 AQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHAL 386
AQFSQE+GLASLG SD D KLA Y +TVEFGLC++ DG YGAGLLSS++EL+HAL
Sbjct: 289 AQFSQEIGLASLGVSDQDTSKLAGCYLYTVEFGLCKEQDG-IKAYGAGLLSSISELKHAL 347
Query: 387 TTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYT 446
++PEK++ FD +E +T++Q Y+ + SF +AK +MRAFA +++RPF + ++ T
Sbjct: 348 SSPEKVRAFDAVTASCQESHVTAFQPVYFLSPSFSQAKHEMRAFAATLERPFVLSFDEET 407
Query: 447 QSVEVLSNAQKITALVSELRGDLCIVSSAI 476
SV+V I + VS++ DL ++S A+
Sbjct: 408 SSVKVFDKLSSIQSAVSKMSHDLVVISKAL 437
>UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61;
Coelomata|Rep: Tyrosine 3-monooxygenase - Mus musculus
(Mouse)
Length = 498
Score = 402 bits (990), Expect = e-110
Identities = 184/337 (54%), Positives = 248/337 (73%), Gaps = 2/337 (0%)
Query: 145 EMPWFPRKISDLDRAQN-VLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPK 203
++PWFPRK+S+LD+ + V + +LD DHPGF D YR+RR+ A IA YK G PIP
Sbjct: 163 KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGEPIPH 222
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
V+YT+ EI TW V+ L LY HAC E+LE + L +YCGYRED++PQLEDVS FLK
Sbjct: 223 VEYTKEEIATWKEVYATLKGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSHFLKE 282
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
+TGFQLRPVAG LS RDFL+ LAFRVF CTQYIRH+S P ++PEPDCCHELLGH+P+LA+
Sbjct: 283 RTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLAD 342
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
+FAQFSQ++GLASLGASD +I+KL+T+Y+FTVEFGLC+Q +G YGAGLLSS EL
Sbjct: 343 RTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQ-NGELKAYGAGLLSSYGELL 401
Query: 384 HALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYN 443
H+L+ +++ FDPD + +YQ Y+ ++SF +AK+K+R +A IQRPF V+++
Sbjct: 402 HSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFD 461
Query: 444 PYTQSVEVLSNAQKITALVSELRGDLCIVSSAIKKIS 480
PYT +++VL + I + ++ +L ++ A+ IS
Sbjct: 462 PYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAIS 498
>UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28;
Deuterostomia|Rep: Tyrosine 3-monooxygenase - Homo
sapiens (Human)
Length = 528
Score = 398 bits (979), Expect = e-109
Identities = 181/336 (53%), Positives = 249/336 (74%), Gaps = 2/336 (0%)
Query: 145 EMPWFPRKISDLDRAQN-VLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPK 203
++PWFPRK+S+LD+ + V + +LD DHPGF D +YR+RR+ A IA Y++G PIP+
Sbjct: 193 KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPR 252
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
V+YT EI TW V+ L LY HAC E+LE + L ++ GYREDN+PQLEDVS FLK
Sbjct: 253 VEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKE 312
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
+TGFQLRPVAG LS RDFL+ LAFRVF CTQYIRH+S P ++PEPDCCHELLGH+P+LA+
Sbjct: 313 RTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLAD 372
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
+FAQFSQ++GLASLGASD +I+KL+TL +FTVEFGLC+Q +G YGAGLLSS EL
Sbjct: 373 RTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLCKQ-NGEVKAYGAGLLSSYGELL 431
Query: 384 HALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYN 443
H L+ +I+ FDP+ + +YQ+ Y+ ++SF +AK+K+R++A IQRPF V+++
Sbjct: 432 HCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFD 491
Query: 444 PYTQSVEVLSNAQKITALVSELRGDLCIVSSAIKKI 479
PYT +++VL + Q + + ++ +L ++ A+ I
Sbjct: 492 PYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 527
>UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 522
Score = 397 bits (977), Expect = e-109
Identities = 198/442 (44%), Positives = 284/442 (64%), Gaps = 21/442 (4%)
Query: 41 QAQAESERISVMFTLKNQVG--GLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
Q ++ R +V F+ K +G L AL VFQ + + H+ESR S + L+ E
Sbjct: 98 QQESAIRRFTVTFSSKEDMGFGSLSEALRVFQKRKVTLTHVESRPSNKIDGQIEFLMQCE 157
Query: 99 CDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEMPWFPRKISDLDR 158
+ + L++ + + + P WFP ++ +LDR
Sbjct: 158 TKGSSSKNVLTALQKVADNVRLEKEEITKRGP-----------------WFPTRVHELDR 200
Query: 159 AQNVLM-YGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIV 217
++L Y +LD +HPGF D YR+RR++ A +A YK+G PIP+V+YT+ E++TWG++
Sbjct: 201 CTHLLSNYEPDLDDEHPGFTDKDYRERRQRIADVAFKYKHGQPIPRVEYTDDELRTWGLI 260
Query: 218 FRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLS 277
+R+L L+ HAC E+++ + L K Y E +PQ EDVS+FLK KTGFQLRPVAG LS
Sbjct: 261 YRQLKALFPTHACKEHIDAFNILEKEGLYSESFIPQHEDVSNFLKGKTGFQLRPVAGLLS 320
Query: 278 PRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLAS 337
RDFL+ LAFRVF TQY+RHSS P +TPEPDCCHELLGH+P+LA+P+FAQFSQE+GLAS
Sbjct: 321 ARDFLASLAFRVFQATQYVRHSSAPMHTPEPDCCHELLGHVPMLADPTFAQFSQEIGLAS 380
Query: 338 LGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDP 397
LG +D DI +LATLY+FTVEFGLCRQ +G GAGLLS+ ELQ+AL+ + + F+P
Sbjct: 381 LGVADEDITRLATLYWFTVEFGLCRQ-NGETRACGAGLLSAFGELQYALSDKPEHRPFEP 439
Query: 398 DITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQK 457
+ T +E +YQ Y+ DSF +A+ K+R +A + RP+ VRY+PYTQS++V+ K
Sbjct: 440 NKTAIQEYQDKNYQPIYFVADSFSDAQSKLRLYAMKMARPYNVRYDPYTQSIQVIDKVDK 499
Query: 458 ITALVSELRGDLCIVSSAIKKI 479
+ + +L G + +++SAI+K+
Sbjct: 500 LRDAIRDLNGQMVVLTSAIEKL 521
>UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15;
Endopterygota|Rep: Tyrosine 3-monooxygenase - Drosophila
melanogaster (Fruit fly)
Length = 579
Score = 377 bits (927), Expect = e-103
Identities = 192/440 (43%), Positives = 278/440 (63%), Gaps = 18/440 (4%)
Query: 42 AQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDP 101
A+A + +++ LK + L R L + V H+ESR+S E D+L+ ++
Sbjct: 152 AEAAMQSAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGVDHDVLIKLDMTR 211
Query: 102 QRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFG-EMPWFPRKISDLDRAQ 160
+ QL R L+ Q+G + M+ A + + PWFP+ S+LD
Sbjct: 212 GNLLQLIRSLR-----------QSGSF----SSMNLMADNNLNVKAPWFPKHASELDNCN 256
Query: 161 NVLM-YGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFR 219
+++ Y +LD +HPGF D +YR+RR++ A IA YKYG PIP + Y++ E+KTW VF+
Sbjct: 257 HLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFK 316
Query: 220 ELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPR 279
+ L KHAC EY + +L + E LPQL+++S FL++ TGF LRP AG L+ R
Sbjct: 317 TVQDLAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAAGLLTAR 376
Query: 280 DFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLG 339
DFL+ LAFR+F TQY+RH + P++TPEPD HELLGHMPLLA+PSFAQFSQE+GLASLG
Sbjct: 377 DFLASLAFRIFQSTQYVRHVNSPYHTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLG 436
Query: 340 ASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDI 399
ASD +I+KL+T+Y+FTVEFGLC++ G YGAGLLSS EL HA++ + + F+P
Sbjct: 437 ASDEEIEKLSTVYWFTVEFGLCKE-HGQIKAYGAGLLSSYGELLHAISDKCEHRAFEPAS 495
Query: 400 TVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQKIT 459
T + YQ YY +SFE+AK+K R + ++ RPF VR+NP+T+ VEVL + K+
Sbjct: 496 TAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLE 555
Query: 460 ALVSELRGDLCIVSSAIKKI 479
LV ++ ++ +++AI K+
Sbjct: 556 TLVHQMNTEILHLTNAISKL 575
>UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF14627, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 488
Score = 360 bits (885), Expect = 5e-98
Identities = 201/460 (43%), Positives = 272/460 (59%), Gaps = 53/460 (11%)
Query: 49 ISVMFTLKN-QVGGLVRALSVFQDLGINVLHIESR---KSMTEVSSADILVDVECDPQRM 104
+++ FTL+N + L R L VF+ + H+E+R K + V E +
Sbjct: 47 LNIFFTLRNSKTPALSRTLKVFETFEAKIHHLETRPCRKLKDNQEGLEYFVRCEVHLSDV 106
Query: 105 EQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEMPWFPRKISDLDRAQN-VL 163
L LKR +D + T E + WFP+KI+DLD+ + V
Sbjct: 107 STLIGSLKRNAEDVK-----TTKEV---------------KFHWFPKKIADLDKCHHLVT 146
Query: 164 MYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHK 223
+ +LD DHPG+ D YR+RR+ +A Y++G IP+V+YTE EI TW V+ L
Sbjct: 147 KFDPDLDQDHPGYTDAAYRQRRKMIGDVAFRYRHGESIPRVEYTEEEIGTWREVYLTLRD 206
Query: 224 LYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLS 283
LY HAC E+LE + L K+CGY DN+PQLEDVS FLK +TGF LRPVAG LS RDFL+
Sbjct: 207 LYATHACSEHLEAFRLLEKHCGYSPDNIPQLEDVSCFLKERTGFTLRPVAGLLSARDFLA 266
Query: 284 GLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELG--------- 334
LAFRVF CTQYIRH+S P ++PEPDC HELLGH+P+LAN +FAQFSQ G
Sbjct: 267 SLAFRVFQCTQYIRHASSPMHSPEPDCVHELLGHVPMLANSTFAQFSQVRGRQRTFCPLR 326
Query: 335 -------------LASL-----GASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLL 376
L SL GASD DI+KL+TLY+FTVE+GLC+Q +G YGAGLL
Sbjct: 327 LSYVFANSPWIHPLQSLGLASLGASDEDIEKLSTLYWFTVEYGLCKQ-NGEVKAYGAGLL 385
Query: 377 SSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQR 436
SS EL H+L+ +++ FDPD + +YQ Y+ ++SF +AKEK R + I+R
Sbjct: 386 SSYGELVHSLSDEPEVREFDPDAAAVQPYQDQTYQPVYFISESFADAKEKFRRYVAGIKR 445
Query: 437 PFGVRYNPYTQSVEVLSNAQKITALVSELRGDLCIVSSAI 476
PF VR++PYT S+EVL N KI + ++ +L +++ A+
Sbjct: 446 PFSVRFDPYTTSIEVLDNPLKIQGGLEGVKDELKMLADAL 485
>UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia
japonica|Rep: Tyrosine hydroxylase - Dugesia japonica
(Planarian)
Length = 488
Score = 351 bits (863), Expect = 3e-95
Identities = 163/339 (48%), Positives = 235/339 (69%), Gaps = 2/339 (0%)
Query: 142 DFGEMPWFPRKISDLDRAQNVLM-YGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHP 200
+ E W P+ ISDLD ++++ + E+ +DHPGF D IY+ RR + A IA N+KYG
Sbjct: 148 EIAEDIWIPKHISDLDSCNHLMLKFQPEMASDHPGFHDKIYKSRRMEIAEIAFNFKYGDK 207
Query: 201 IPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSF 260
IP+V+Y E+E +TW + L LY+ +AC E L +L + CGY +++PQLED+S++
Sbjct: 208 IPRVEYFESEKETWREAYITLTSLYKDYACKEQLIGIKKLEEKCGYGPNDIPQLEDISNY 267
Query: 261 LKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPL 320
LK+ +GFQLRPVAG LS RDFL+ LAFRVF CTQY RH S P +TPEPDC HELLGH+P+
Sbjct: 268 LKKTSGFQLRPVAGLLSARDFLASLAFRVFQCTQYTRHHSKPLHTPEPDCIHELLGHVPM 327
Query: 321 LANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVA 380
L++ FA+FSQE+GL SLGASD+DI++LATLY+FT+EFGLC + + +GAGLLSS
Sbjct: 328 LSDAEFAEFSQEIGLCSLGASDSDIERLATLYWFTIEFGLCYE-NKKIKAFGAGLLSSFG 386
Query: 381 ELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGV 440
EL+HA++ + + FDP + YQ YY DS + KEK+R FA+SI+R +
Sbjct: 387 ELKHAISNIPEHRNFDPQVASVTPYKDEDYQPVYYVIDSVTDMKEKVRQFAKSIKRQNPI 446
Query: 441 RYNPYTQSVEVLSNAQKITALVSELRGDLCIVSSAIKKI 479
RY+PYT+++E+L+N + + L ++ +L + +++ +
Sbjct: 447 RYDPYTETIEILNNKKSVCHLGRVIKHELDTMENSLSSM 485
>UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistosoma
mansoni|Rep: Tyrosine 3-monooxygenase - Schistosoma
mansoni (Blood fluke)
Length = 465
Score = 324 bits (797), Expect = 2e-87
Identities = 151/310 (48%), Positives = 213/310 (68%), Gaps = 8/310 (2%)
Query: 148 WFPRKISDLDRAQNVLM-YGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQY 206
W+P+ ISDLD+ Q++L + EL DHPGF D +YR+RRE A IA YKYG IP+V+Y
Sbjct: 129 WYPKHISDLDKCQHLLRKFQPELQTDHPGFHDKVYRERREAIAKIAFQYKYGDRIPEVEY 188
Query: 207 TETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTG 266
T+ EI+TWG+VF ++ ++ AC EY++ + L KYC Y +++PQL+ + F+ R +G
Sbjct: 189 TKEEIETWGLVFTKMKAVHASRACREYIDGFQLLEKYCNYNSESIPQLQTICEFMHRTSG 248
Query: 267 FQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSF 326
F++RPVAG +SP+DFL+ LAFRVF CTQYIRH S P +TPEPDC HEL+GHMP+L N F
Sbjct: 249 FRIRPVAGLVSPKDFLASLAFRVFQCTQYIRHHSRPMHTPEPDCIHELIGHMPMLVNRQF 308
Query: 327 AQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHA- 385
A FSQELGLASLGAS+ +I +L+TLY+FTVEFGLC + +G GAG++SS EL++A
Sbjct: 309 ADFSQELGLASLGASEEEITRLSTLYWFTVEFGLCNE-NGETRALGAGIMSSYGELENAF 367
Query: 386 --LTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYN 443
L+ E D + V+++ YQ Y+ T+S E K ++R + + + Y+
Sbjct: 368 SDLSVKEPFNINDAAVQVYDD---VGYQKIYFVTESIESMKRELRNYINTSGKSTIPIYD 424
Query: 444 PYTQSVEVLS 453
P T++V + S
Sbjct: 425 PITETVHMKS 434
>UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona
intestinalis|Rep: Tyrosine 3-monooxygenase - Ciona
intestinalis (Transparent sea squirt)
Length = 429
Score = 311 bits (764), Expect = 2e-83
Identities = 144/311 (46%), Positives = 211/311 (67%), Gaps = 6/311 (1%)
Query: 148 WFPRKISDLDRAQNVLM-YGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQY 206
WFPR +++L+ + Y + D++HPGF DP+Y +RR + A+ YK+G IP V Y
Sbjct: 119 WFPRHVTELELCRGTKTDYEPDKDSNHPGFNDPVYVERRNYISNTAHFYKHGTDIPTVDY 178
Query: 207 TETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTG 266
T + +TW +V++ L +L+ HAC Y +N+ +L K CGY + +PQL+ VS FLK +TG
Sbjct: 179 TNEDRQTWSVVYKTLKRLHATHACKVYKDNFQRLEKECGYSPNKIPQLQTVSEFLKEQTG 238
Query: 267 FQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSF 326
F+L+P G ++PRDFL+ LAF+VF CTQYIRH + P ++PEPDCCHEL+GH+P+L +P+F
Sbjct: 239 FKLQPAPGIITPRDFLASLAFKVFQCTQYIRHPASPMHSPEPDCCHELIGHIPMLLDPTF 298
Query: 327 AQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHAL 386
A +SQ++GLASLG SD+DI KLA LY+FTVEFGLC++ + YGAGL+SS ELQHAL
Sbjct: 299 ALYSQQIGLASLGVSDSDITKLAALYWFTVEFGLCKE-NNVLKAYGAGLMSSYGELQHAL 357
Query: 387 TTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAE-SIQRPFGVRYNP- 444
+ + T + + YQ Y+ ++SF+EA ++RAF++ +R F + YN
Sbjct: 358 SDVPMHLPLQAERTCLQPYEDSVYQPIYFVSESFDEAFNQVRAFSQHCTKRGFDITYNEN 417
Query: 445 --YTQSVEVLS 453
Y Q+V ++
Sbjct: 418 DGYIQTVPYIN 428
>UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n=3;
Leishmania|Rep: Aromatic amino acid hydroxylase-like -
Leishmania major
Length = 453
Score = 301 bits (738), Expect = 4e-80
Identities = 145/310 (46%), Positives = 198/310 (63%), Gaps = 6/310 (1%)
Query: 146 MPWFPRKISDLDRA-QNVLMYGSELDAD----HPGFKDPIYRKRREQFAAIANNYKYGHP 200
+PW+P + DLD Q+ L G EL D HPGF D +YR RR + +A NYK G P
Sbjct: 124 IPWYPTEPKDLDELDQSTLAAGEELQEDPENPHPGFHDEVYRARRREIVGLAKNYKTGDP 183
Query: 201 IPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSF 260
IP V YTE E + W +V+ L +LY HAC +Y +P L++ PQL DVS F
Sbjct: 184 IPIVNYTEEENRVWTVVYDHLTRLYPTHACQQYNYVFPLLLENGVLSRTKTPQLRDVSEF 243
Query: 261 LKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPL 320
L TGF +RPV G L+ RDFL+ LAFRVF+ TQYIRH++ P YTPEPD H+++GH+PL
Sbjct: 244 LNEATGFTVRPVTGLLTSRDFLNALAFRVFYSTQYIRHAAQPLYTPEPDMVHDIIGHLPL 303
Query: 321 LANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVA 380
L++P FA F+Q +GLASLGASD +DKLA +Y+++VEFGLC + G YGAG+LSS
Sbjct: 304 LSDPDFANFTQTIGLASLGASDELLDKLAKVYWYSVEFGLCSE-GGRRKAYGAGILSSCG 362
Query: 381 ELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGV 440
EL++AL+ + +DP + IT YQ Y+ +SF +A+ K+ A+ S ++P
Sbjct: 363 ELEYALSDKPECVPWDPTMASKTPFPITKYQPLYFVAESFSDAQRKLEAWLSSQEKPLYT 422
Query: 441 RYNPYTQSVE 450
YN Y++ V+
Sbjct: 423 VYNSYSRRVQ 432
>UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3;
Caenorhabditis|Rep: Tyrosine 3-monooxygenase -
Caenorhabditis elegans
Length = 454
Score = 295 bits (724), Expect = 2e-78
Identities = 145/333 (43%), Positives = 202/333 (60%), Gaps = 2/333 (0%)
Query: 148 WFPRKISDLDRAQN-VLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQY 206
WFPR IS+LD+ + Y D HPG D Y RR+ A +K+G I V Y
Sbjct: 117 WFPRHISELDQCSKCITKYEPTTDPRHPGHGDVAYIARRKFLNDQALEFKFGDEIGYVDY 176
Query: 207 TETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTG 266
TE E TW V+ +L L+ H C Y +N L + D +PQ+ DV+ FL++KTG
Sbjct: 177 TEEEHATWKAVYEKLGDLHLSHTCAVYRQNLKILQEEKVLTADRIPQIRDVNKFLQKKTG 236
Query: 267 FQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSF 326
F+LRP +G LS RDFL+ LAFRVF T Y+RH P ++PEPD HELLGH+P+ ++P
Sbjct: 237 FELRPCSGLLSARDFLASLAFRVFQTTTYLRHHKSPHHSPEPDLIHELLGHVPMFSDPLL 296
Query: 327 AQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHAL 386
AQ SQ++GL SLGASD I+KL+T+Y+F VEFGLC++ DG GAGLLS+ EL HA
Sbjct: 297 AQMSQDIGLMSLGASDEHIEKLSTVYWFIVEFGLCKE-DGKLKAIGAGLLSAYGELMHAC 355
Query: 387 TTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYT 446
+ + K FDP +T ++ YQ Y+ DS +A K+R +A S+ RPF V Y+P+T
Sbjct: 356 SDAPEHKDFDPAVTAVQKYEDDDYQPLYFVADSIHDALAKLRKYASSMDRPFSVVYDPFT 415
Query: 447 QSVEVLSNAQKITALVSELRGDLCIVSSAIKKI 479
+S+E + ++ + S L DL ++ A ++
Sbjct: 416 KSIEAIESSADLEKAFSRLSNDLSAITHAADRM 448
>UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 431
Score = 254 bits (622), Expect = 4e-66
Identities = 125/305 (40%), Positives = 183/305 (60%), Gaps = 9/305 (2%)
Query: 146 MPWFPRKISDLDRAQNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQ 205
+PW+PR DL ++ E + DHP FKD YRKRRE+ A ++ + G P+P +
Sbjct: 110 VPWYPRNDEDLKTIGLIMEVKEENNQDHPQFKDHEYRKRREEIAKLSQQHLIGEPVPYIN 169
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YTE E TW ++ L + +K YL N ++ G++ +PQL D+ ++LK +T
Sbjct: 170 YTEQEEVTWKKIYSILRERVEKVMSQRYLRNLVKIENALGFKY-KIPQLRDIDAYLKAET 228
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
GF+++ G LS R+FL+ L RVF CTQYIRH S P YTPEPD HEL+GH+PL A+
Sbjct: 229 GFRIKATHGILSQREFLNALGHRVFCCTQYIRHHSTPEYTPEPDIVHELVGHVPLFADKE 288
Query: 326 FAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAE---- 381
A SQE+G+ S G D+ +L TLY+FT+EFG C++ +G +GAG+ SS+ E
Sbjct: 289 VADLSQEIGILSCGTEQKDLSRLGTLYWFTLEFGACKE-NGQIKGFGAGIASSIGECDVS 347
Query: 382 -LQHALTTPEK--IKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPF 438
+Q+ K ++FDP I I + Q Y YT+SFEEA +++ F +S+Q+PF
Sbjct: 348 NIQYLFQNFPKANYEKFDPFIHADRPYPIQTVQPVYMYTESFEEAMQELIIFGKSLQKPF 407
Query: 439 GVRYN 443
G+ Y+
Sbjct: 408 GLYYD 412
>UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid
hydroxylase family protein; n=2; Tetrahymena thermophila
SB210|Rep: Biopterin-dependent aromatic amino acid
hydroxylase family protein - Tetrahymena thermophila
SB210
Length = 448
Score = 249 bits (609), Expect = 2e-64
Identities = 143/410 (34%), Positives = 226/410 (55%), Gaps = 23/410 (5%)
Query: 45 ESERIS-VMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQR 103
E++++ + ++QVG L L VF+ IN+ IES+ + +++ + R
Sbjct: 46 ENDKVEELQIITRDQVGSLSNVLDVFKQHSINLTQIESKLLNKRRDNQNVMFVCTFEGNR 105
Query: 104 MEQLKRMLKREVQD-FEVVPPQTGDEFPPPTPMSAAASFDFGEMPWFPRKISDLDRAQNV 162
Q + +E+Q F++V +F T + +PWFPR +DL
Sbjct: 106 KYQNVQQAFQELQSKFDIV------KFSDETNV----------VPWFPRDRNDLQYIGQD 149
Query: 163 LMYGSELDA-DHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFREL 221
LM E + D F D YRKRR+ A ++ ++ G PIP ++YTE E +TW ++ +L
Sbjct: 150 LMRVEEDNCKDSLQFTDTEYRKRRDYIAQVSKSHILGQPIPILEYTEQENQTWRTIYNKL 209
Query: 222 HKLYQKHACPE-YLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRD 280
Y K C + Y N QL + G ++ +PQL D+ ++L++KT F+++ G LS R+
Sbjct: 210 SS-YHKDLCTDRYNYNKRQLERELGI-QNQIPQLRDLDAYLRQKTNFKIKAAHGILSQRE 267
Query: 281 FLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGA 340
FL+ LA RVF TQYIRH YTPEPD HE++GH+P+ A+P A SQE+GL S+GA
Sbjct: 268 FLNALAHRVFFSTQYIRHHKTVEYTPEPDIVHEVVGHIPMFADPVVADISQEIGLLSIGA 327
Query: 341 SDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDIT 400
+D + +L +Y+FT+EFG C++ +G YGAG++ + E +H L+ + K DP
Sbjct: 328 NDEQLRRLGNIYWFTLEFGACKE-NGKMKAYGAGIIGCIGECEHFLSQNSRFKYLDPFKD 386
Query: 401 VHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVE 450
E I Q Y YT+SFEE E++ F E +++P Y+ T+++E
Sbjct: 387 CDREYPIQKVQPVYCYTNSFEECLERLVKFGEQMKKPMKTWYDFNTETIE 436
>UniRef50_Q4THP6 Cluster: Chromosome undetermined SCAF2776, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF2776,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 218
Score = 222 bits (542), Expect = 2e-56
Identities = 115/216 (53%), Positives = 142/216 (65%), Gaps = 52/216 (24%)
Query: 145 EMPWFPRKISDLDRAQN-VLMYGSELDADHP-------------------------GFKD 178
++PWFP KIS+LD+ + VLMYG+ELDADHP GFKD
Sbjct: 3 DVPWFPMKISELDQCSHRVLMYGTELDADHPVSDPLEPPRSGCLPADRFPPSARRQGFKD 62
Query: 179 PIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWP 238
+YR+RR+ F +A NYK+G PIP+V+YT E++TWG+VFREL KLY HAC EYL+N P
Sbjct: 63 QVYRQRRKYFVEVAMNYKFGQPIPRVEYTPEEVRTWGVVFRELTKLYPTHACREYLKNLP 122
Query: 239 QLVKYCGYREDNLPQLEDVSSFLK--------------------------RKTGFQLRPV 272
L K+CGYREDN+PQLEDVS FL+ ++GF +RPV
Sbjct: 123 LLSKHCGYREDNVPQLEDVSLFLRGPLDVVRNSQSDKVAVTVTRGPWCVPERSGFTVRPV 182
Query: 273 AGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEP 308
AGYLSPRDFL+GLA+RVF+CTQYIRHS+DP YTPEP
Sbjct: 183 AGYLSPRDFLAGLAYRVFNCTQYIRHSTDPLYTPEP 218
>UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=31;
Eutheria|Rep: Tyrosine hydroxylase isoform D2,8,9 - Homo
sapiens (Human)
Length = 407
Score = 186 bits (454), Expect = 9e-46
Identities = 90/205 (43%), Positives = 136/205 (66%), Gaps = 1/205 (0%)
Query: 275 YLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELG 334
Y R ++ +AF+ H R DCCHELLGH+P+LA+ +FAQFSQ++G
Sbjct: 203 YRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWDCCHELLGHVPMLADRTFAQFSQDIG 262
Query: 335 LASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKR 394
LASLGASD +I+KL+TLY+FTVEFGLC+Q +G YGAGLLSS EL H L+ +I+
Sbjct: 263 LASLGASDEEIEKLSTLYWFTVEFGLCKQ-NGEVKAYGAGLLSSYGELLHCLSEEPEIRA 321
Query: 395 FDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSN 454
FDP+ + +YQ+ Y+ ++SF +AK+K+R++A IQRPF V+++PYT +++VL +
Sbjct: 322 FDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDS 381
Query: 455 AQKITALVSELRGDLCIVSSAIKKI 479
Q + + ++ +L ++ A+ I
Sbjct: 382 PQAVRRSLEGVQDELDTLAHALSAI 406
Score = 90.6 bits (215), Expect = 8e-17
Identities = 37/71 (52%), Positives = 52/71 (73%), Gaps = 1/71 (1%)
Query: 145 EMPWFPRKISDLDRAQN-VLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPK 203
++PWFPRK+S+LD+ + V + +LD DHPGF D +YR+RR+ A IA Y++G PIP+
Sbjct: 166 KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPR 225
Query: 204 VQYTETEIKTW 214
V+YT EI TW
Sbjct: 226 VEYTAEEIATW 236
>UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3;
Actinomycetales|Rep: Tyrosine 3-monooxygenase - Frankia
sp. EAN1pec
Length = 296
Score = 178 bits (434), Expect = 2e-43
Identities = 100/263 (38%), Positives = 143/263 (54%), Gaps = 8/263 (3%)
Query: 169 LDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKH 228
L HPG D Y+ RR Q A +A ++ G P+P+V YTE E W +V +L Y+
Sbjct: 23 LARSHPGAADREYQARRNQIAELALRWRPGQPVPRVAYTEAEHAVWRLVTGKLALAYRGC 82
Query: 229 ACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFR 288
AC E+L ++ G D +PQL++VS L TGF+ P AG + R+F LA
Sbjct: 83 ACAEFLRGAARM----GLPTDRIPQLDEVSGPLSELTGFRYVPAAGLVGLREFYGSLADG 138
Query: 289 VFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDAD-IDK 347
VFH TQY+RH + PFYTPEPD HE++GH LA+ FA + G A+ A AD +
Sbjct: 139 VFHATQYLRHHTVPFYTPEPDIIHEVVGHANALASDRFAALYRAAGEAARRAESADTLQF 198
Query: 348 LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECII 407
++ +++FT+EFG + DG YGAG+LSS E+ + ++ D I + I
Sbjct: 199 ISKVFWFTLEFGTVYE-DGELKAYGAGILSSYGEMAEFRSV--NVRPLDVAIMGTTDYDI 255
Query: 408 TSYQNAYYYTDSFEEAKEKMRAF 430
T YQ Y DSF + ++ + F
Sbjct: 256 TRYQPVLYAADSFGQVEDVVGGF 278
>UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan
hydroxylase D1; n=7; Danio rerio|Rep: PREDICTED: similar
to tryptophan hydroxylase D1 - Danio rerio
Length = 488
Score = 169 bits (410), Expect = 2e-40
Identities = 74/89 (83%), Positives = 82/89 (92%)
Query: 262 KRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLL 321
+++TGF +RPVAGYLSPRDFL+GLAFRVFHCTQY+RHSSDP YTPEPD CHELLGH+PLL
Sbjct: 360 RKRTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLL 419
Query: 322 ANPSFAQFSQELGLASLGASDADIDKLAT 350
A PSFAQFSQE+GLASLGASD I KLAT
Sbjct: 420 AEPSFAQFSQEIGLASLGASDDSIQKLAT 448
>UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1;
Salinibacter ruber DSM 13855|Rep: Tryptophan
5-hydroxylase 1 - Salinibacter ruber (strain DSM 13855)
Length = 278
Score = 142 bits (344), Expect = 2e-32
Identities = 80/232 (34%), Positives = 120/232 (51%), Gaps = 6/232 (2%)
Query: 198 GHPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDV 257
G I Y + + +TW I+ + AC Y+ L G D +P L D+
Sbjct: 43 GDEIEYPDYPDEDHETWQILVERQMEQLPGRACEAYMRGQDVL----GLEGDRIPDLADL 98
Query: 258 SSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGH 317
S L +TG+++ V G + ++F S L+ R F T Y+R + YTP PDC H++ GH
Sbjct: 99 SRRLNEETGWEVANVPGLIHEKNFFSLLSQRKFPSTNYVRGREELDYTPAPDCFHDIFGH 158
Query: 318 MPLLANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLS 377
MP+L P FA F Q G A+ A AD +L ++FTVEFGL Q G ++GAG++S
Sbjct: 159 MPMLTQPEFADFYQLYGQAAQNAEGADRPRLERFHWFTVEFGLI-QEQGEKRIFGAGIVS 217
Query: 378 SVAELQHALTTPEKIKRFDPD-ITVHEECIITSYQNAYYYTDSFEEAKEKMR 428
S E+ HAL+ + FDP+ I ++ + + Q + DSFE+ + R
Sbjct: 218 SNEEVTHALSEEVTLHPFDPEHIVEKDDYEVYNLQEELFVLDSFEQLVDGFR 269
>UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1;
Acidobacteria bacterium Ellin345|Rep: Phenylalanine
4-monooxygenase - Acidobacteria bacterium (strain
Ellin345)
Length = 250
Score = 135 bits (327), Expect = 2e-30
Identities = 75/222 (33%), Positives = 119/222 (53%), Gaps = 6/222 (2%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
QY++ E TW ++ + HAC EYLE ++ G R + +P + D++ L+ +
Sbjct: 23 QYSDVEHGTWKTLYERRMEQLSTHACKEYLEG----LRVLGMRAERMPVISDINKTLQTR 78
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
T + L PV+G+L R F LA RVF T YIR YTPEPD H++ GH+P+ A+
Sbjct: 79 TNWMLLPVSGFLPGRTFFDLLAARVFPVTTYIRKPDSLDYTPEPDIFHDIFGHVPMHAHK 138
Query: 325 SFAQFSQELG-LASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
FA + Q +A +DAD ++L L+++TVEFGL R+ +YG+G++SSV E
Sbjct: 139 VFADYLQAFAQIARQITNDADQERLGRLFWYTVEFGLIRE-GSDVKMYGSGVISSVKEGD 197
Query: 384 HALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKE 425
+ + KI F + + + Q + ++FE+ E
Sbjct: 198 NVVHRGCKIHDFSLEEVLDTHVKVDELQPTLFAIENFEQIYE 239
>UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4;
Legionella pneumophila|Rep: Phenylalanine-4-hydroxylase
- Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 281
Score = 134 bits (325), Expect = 4e-30
Identities = 76/219 (34%), Positives = 111/219 (50%), Gaps = 6/219 (2%)
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
V Y+ E + W I+F KL AC E+L L G +PQL +VS LK
Sbjct: 27 VDYSAQENRIWNILFERQLKLLPGRACDEFLSGLQTL----GLNSSTIPQLPEVSERLKA 82
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
KTG+Q+ PVA +S R+F LA + F +IR + Y EPD HEL GH P+L +
Sbjct: 83 KTGWQVAPVAALISAREFFELLAEKYFPAATFIRSEEELDYVQEPDIFHELFGHCPMLTD 142
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
+A+F + L + D L +++FTVEFGL + P G YG G+LSS++E
Sbjct: 143 RVYAEFVHDYACKVLTFPEQDWPLLQRMFWFTVEFGLIKTPKG-LRAYGGGILSSISETV 201
Query: 384 HALTTPEKIK-RFDPDITVHEECIITSYQNAYYYTDSFE 421
+ + + ++ FDP + I Q Y+ DS++
Sbjct: 202 YCVESDIPVRILFDPVVAFRMPYRIDQLQPVYFVIDSYQ 240
>UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia pickettii 12D
Length = 349
Score = 134 bits (324), Expect = 5e-30
Identities = 87/263 (33%), Positives = 130/263 (49%), Gaps = 17/263 (6%)
Query: 175 GFKDPIYRKRREQFA------AIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKH 228
GF + K REQFA + ++ P+ + YT + TW ++ L
Sbjct: 53 GFNGTLTDKLREQFAEGLDGQTLRADFTMQQPVHR--YTAADHATWRTLYDRQEALLPGR 110
Query: 229 ACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFR 288
C E+L+ L G D +P + ++ L R TG+Q+ V G + F LA R
Sbjct: 111 VCDEFLQGLSTL----GMSRDAVPSFDQLNETLMRATGWQIVAVPGLVPDEVFFDHLANR 166
Query: 289 VFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASD-ADIDK 347
F + ++R Y EPDC H++ GH+PLL NP FA + + G L A+ +D
Sbjct: 167 RFPASWWMRRPDQLDYLQEPDCFHDIFGHVPLLINPIFADYMEAYGKGGLKAARLGQLDM 226
Query: 348 LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHAL--TTPEKIKRFDPDITVHEEC 405
LA LY++TVEFGL R P G +YGAG++SS +E +AL +P +I FD +
Sbjct: 227 LARLYWYTVEFGLIRTPAG-LRIYGAGIVSSKSESVYALDSASPNRI-GFDVRRIMRTRY 284
Query: 406 IITSYQNAYYYTDSFEEAKEKMR 428
I ++Q Y+ DSFE+ + R
Sbjct: 285 RIDTFQKTYFTIDSFEQLFDATR 307
>UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1;
Rickettsia bellii RML369-C|Rep:
Phenylalanine-4-hydroxylase - Rickettsia bellii (strain
RML369-C)
Length = 246
Score = 130 bits (315), Expect = 6e-29
Identities = 77/220 (35%), Positives = 121/220 (55%), Gaps = 7/220 (3%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
++TET+ + W +F +L + A E +E +L K C D +P+ +++ L ++
Sbjct: 17 KFTETDHEIWKTLFNRHTELLKNRATNEIVEGIEKL-KICN---DRIPKFTELNRILMKE 72
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
T F + PV G++ F LA R F T +IR Y EPD H++ GH+PLL NP
Sbjct: 73 TNFSIIPVKGFIPEDLFFKFLAERKFPSTCFIRQPHQLDYLEEPDIFHDVFGHVPLLVNP 132
Query: 325 SFAQFSQELGLASLGASDADIDKLAT-LYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
FA F Q+ GL L A +A + K A+ LY+FTVEFGL + +G +YGAG++SS E
Sbjct: 133 VFADFMQQFGLKGLEAIEAGMLKFASALYWFTVEFGLIQSNNG-LRIYGAGIISSKGESI 191
Query: 384 HALTTPEKIK-RFDPDITVHEECIITSYQNAYYYTDSFEE 422
++L + ++ FD + + E S+Q Y+ SF++
Sbjct: 192 YSLESEIPMRLEFDLNKVIKTEYETDSFQKTYFVIKSFQQ 231
>UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 313
Score = 130 bits (314), Expect = 8e-29
Identities = 87/263 (33%), Positives = 130/263 (49%), Gaps = 17/263 (6%)
Query: 175 GFKDPIYRKRREQFA------AIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKH 228
GF + K REQFA + ++ P+ + YT + TW ++ L
Sbjct: 17 GFTGTLTDKLREQFAEGLDGQTLRPDFTMEQPVHR--YTAADHATWRTLYDRQEALLPGR 74
Query: 229 ACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFR 288
AC E+L+ L G + +P + ++ L R TG+Q+ V G + F LA R
Sbjct: 75 ACDEFLQGLSTL----GMSREGVPSFDRLNETLMRATGWQIVAVPGLVPDEVFFEHLANR 130
Query: 289 VFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASD-ADIDK 347
F + ++R Y EPD H++ GH+PLL NP FA + Q G L A+ +D
Sbjct: 131 RFPASWWMRRPDQLDYLQEPDGFHDIFGHVPLLINPVFADYMQAYGQGGLKAARLGALDM 190
Query: 348 LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHAL--TTPEKIKRFDPDITVHEEC 405
LA LY++TVEFGL R P G +YGAG++SS +E +AL +P +I FD +
Sbjct: 191 LARLYWYTVEFGLIRTPAG-LRIYGAGIVSSKSESVYALDSASPNRI-GFDVHRIMRTRY 248
Query: 406 IITSYQNAYYYTDSFEEAKEKMR 428
I ++Q Y+ DSFE+ + R
Sbjct: 249 RIDTFQKTYFVIDSFEQLFDATR 271
>UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1;
Moritella sp. PE36|Rep: Phenylalanine-4-hydroxylase -
Moritella sp. PE36
Length = 272
Score = 120 bits (290), Expect = 7e-26
Identities = 65/183 (35%), Positives = 97/183 (53%), Gaps = 5/183 (2%)
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
+ Y++ E TW ++ ++ + AC E++ ++ D +PQL D++ LK+
Sbjct: 24 INYSDEEHNTWATLYNRQTEIIKDRACDEFIAG----IELLQMGADRIPQLPDINRKLKK 79
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
TG+Q+ V + F LA + F +IR +D Y EPD HEL GH PLL N
Sbjct: 80 LTGWQVENVPALIGFERFFELLATKRFPAATFIRTKADIDYIQEPDIFHELFGHCPLLTN 139
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
++A FSQ G L A AD LA LY+FT+EFGL + G ++G G+LSS E
Sbjct: 140 QAYADFSQHYGELGLKADKADRPMLARLYWFTIEFGLMQSQQG-LKIFGGGILSSKQETC 198
Query: 384 HAL 386
++L
Sbjct: 199 YSL 201
>UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=2;
Rhizobium|Rep: Phenylalanine-4-hydroxylase protein -
Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 263
Score = 120 bits (288), Expect = 1e-25
Identities = 76/218 (34%), Positives = 104/218 (47%), Gaps = 6/218 (2%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT E WG ++R KL AC EYL+ VK G R + +PQL DV+ L T
Sbjct: 20 YTPEEDAIWGELYRRQMKLLADKACQEYLDG----VKLLGLRPEKVPQLLDVNRRLNETT 75
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
GF + V + P F L+ F ++R Y EPD HE+ GH PLL N S
Sbjct: 76 GFGVEGVPALIPPSRFYELLSQGKFPLATFLRRREHIDYIEEPDLFHEVFGHCPLLTNQS 135
Query: 326 FAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHA 385
+A F + G ++ L +++FTVEFGL P G C +GAG++SS +E + A
Sbjct: 136 YANFVRHFGETAMRLGKGYSWHLFRIFWFTVEFGLINTPQGRRC-FGAGIVSSPSEAKAA 194
Query: 386 LT-TPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEE 422
T + + FD + I Q YY DSF +
Sbjct: 195 TEGTACEFRPFDLLSVLRTPYRIDILQPIYYVIDSFAD 232
>UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66;
Gammaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Pseudomonas aeruginosa
Length = 262
Score = 119 bits (287), Expect = 2e-25
Identities = 75/237 (31%), Positives = 114/237 (48%), Gaps = 9/237 (3%)
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
+ Y ETE + W + K+ + AC EYL+ QL G + +PQL++++ L+
Sbjct: 17 IHYPETEHQVWNTLITRQLKVIEGRACQEYLDGIEQL----GLPHERIPQLDEINRVLQA 72
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
TG+++ V + + F LA + F +IR + Y EPD HE+ GH PLL N
Sbjct: 73 TTGWRVARVPALIPFQTFFELLASQQFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLTN 132
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
P FA+F+ G L AS + LA LY+ T+EFGL G +YG G+LSS E
Sbjct: 133 PWFAEFTHTYGKLGLKASKEERVFLARLYWMTIEFGLVETDQGK-RIYGGGILSSPKETV 191
Query: 384 HALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDS----FEEAKEKMRAFAESIQR 436
++L+ + F+P + I Q Y+ F+ A+E + A R
Sbjct: 192 YSLSDEPLHQAFNPLEAMRTPYRIDILQPLYFVLPDLKRLFQLAQEDIMALVHEAMR 248
>UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=8; Burkholderiales|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 292
Score = 117 bits (282), Expect = 6e-25
Identities = 77/211 (36%), Positives = 117/211 (55%), Gaps = 17/211 (8%)
Query: 222 HKLYQKH-------ACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAG 274
H+LYQ+ AC E++ P L G +E +P+ E+++ L + T +++ V G
Sbjct: 53 HRLYQRQSALVPGLACDEFIAALPLL----GAKE-RIPRFEEINERLYKATRWEIVAVPG 107
Query: 275 YLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELG 334
+ F + LA R F T ++R ++ Y EPD H+L GH+PLL NP FA Q G
Sbjct: 108 LIPEVPFFTLLANRKFPVTDWLRTPAEFDYIVEPDVFHDLFGHVPLLFNPVFADHMQAYG 167
Query: 335 LASLGA-SDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIK 393
L A + ++L+ LY++TVEFGL RQ +G YGAG+LSS EL +A+ +PE +
Sbjct: 168 AGGLKAHALGACEQLSRLYWYTVEFGLIRQANG-LRAYGAGILSSSGELAYAVQSPEP-Q 225
Query: 394 RFDPDI--TVHEECIITSYQNAYYYTDSFEE 422
R ++ T+ I SYQ Y+ DSF++
Sbjct: 226 RIALNLLRTMRTRYKIDSYQQTYFVIDSFQQ 256
>UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2;
Alphaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Maricaulis maris (strain MCS10)
Length = 293
Score = 117 bits (281), Expect = 8e-25
Identities = 72/224 (32%), Positives = 112/224 (50%), Gaps = 9/224 (4%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
+YT E W ++ + + A PE+ L E +P V+ L++
Sbjct: 25 RYTAGEHAIWTTLYERQMGVLKGRAAPEHFAGLDML----NLNEGGIPDFRRVNEKLEKL 80
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
TG+ + V G + +DF LA R F ++IR Y PEPD H++ GH+PLL P
Sbjct: 81 TGWTVVTVPGLIPEKDFYEHLANRRFVSGRFIRDGETLDYLPEPDIFHDVFGHVPLLTQP 140
Query: 325 SFAQFSQELGLASLGASDAD-IDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
FA + Q G L + + D I +A LY++TVEFGL P+G +YGAG++SS E
Sbjct: 141 VFADYMQAYGKGGLRSLEFDAIKHMARLYWYTVEFGLINTPEGR-RIYGAGIVSSRTESI 199
Query: 384 HAL--TTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKE 425
+L +P ++ FD + + + +Q +Y+ DS+EE E
Sbjct: 200 FSLEGKSPNRL-HFDLERIMQTDYRYDDFQQSYFVIDSYEELME 242
>UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3;
Chloroflexi (class)|Rep: Aromatic amino acid hydroxylase
- Herpetosiphon aurantiacus ATCC 23779
Length = 247
Score = 114 bits (275), Expect = 4e-24
Identities = 73/234 (31%), Positives = 109/234 (46%), Gaps = 7/234 (2%)
Query: 201 IPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSF 260
+ +++Y + + TW +++ L Q+HAC +LE + +LP VS +
Sbjct: 8 LSRLEYPQEDHDTWAALWQRQMPLAQQHACKLFLEG----IDILNLDRTHLPDPLAVSDY 63
Query: 261 LKRKTGFQLRPVAG-YLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMP 319
L TG+ L YL P ++ +A R F T YIR + +TP PD HE GH+P
Sbjct: 64 LNTLTGWALGDAQNAYLGPTEWFEHIAERRFPVTNYIRRPHELEFTPLPDLFHEYFGHLP 123
Query: 320 LLANPSFAQFSQELGLASLGASDADID-KLATLYFFTVEFGLCRQPDGSFCVYGAGLLSS 378
N FA +Q G L A D +A +++F+ EFGL R+ +G V GAGLLSS
Sbjct: 124 AFTNREFADIAQLFGPLYLSAKDERQQLGIARIWWFSTEFGLLRE-NGELKVLGAGLLSS 182
Query: 379 VAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAE 432
EL HAL FD + Y Y+ +S + + + +AE
Sbjct: 183 PGELLHALNPETPRYEFDIERVADTASAPYGYHEHYFILNSLDHLRSIVYEYAE 236
>UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Sphingomonadaceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 290
Score = 109 bits (263), Expect = 1e-22
Identities = 65/219 (29%), Positives = 108/219 (49%), Gaps = 7/219 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
+T + +TW +F +AC +L+ L + +P ++++ LK +
Sbjct: 27 FTPEQHRTWRTLFDRQSAAMGGYACRAFLDGLGLLRRL----RPGVPDFAELNALLKPAS 82
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+++ V G++ F LA R F ++R Y+ EPD H++ GH+P+LANP+
Sbjct: 83 GWEVVAVPGWIPNAPFFEHLANRRFPAANFVRPPEQIAYSEEPDMFHDIFGHVPMLANPA 142
Query: 326 FAQFSQELGLASLGASDADI-DKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQH 384
F F G A L A D L L+ +TVEFGL + +G +G GLLSS+AE
Sbjct: 143 FGDFLVAYGEAGLRAESLGASDYLGRLWLYTVEFGLVVE-EGELRAFGGGLLSSLAETAF 201
Query: 385 ALTTPEKIKRF-DPDITVHEECIITSYQNAYYYTDSFEE 422
ALT PE + + D + + ++Q Y+ + F++
Sbjct: 202 ALTAPEPRRIWLDVERAMRTRYHFDAFQQTYFVVEGFDQ 240
>UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Flexibacteraceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Algoriphagus sp. PR1
Length = 259
Score = 109 bits (262), Expect = 2e-22
Identities = 65/232 (28%), Positives = 115/232 (49%), Gaps = 7/232 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT + K W I+F K A YL+ V+ G+ D + ED++ L + T
Sbjct: 25 YTSEDFKVWKILFERQMPNLPKAASKAYLDG----VEIVGFSADRIANFEDLNQILAKTT 80
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G++++ V G + F L R F + ++R Y EPD H+ HMP+L N
Sbjct: 81 GWEVQVVPGLIDDDLFFGLLNNRRFPSSTWLRKMEQLDYLQEPDMFHDAFAHMPMLTNQP 140
Query: 326 FAQFSQEL-GLASLGASDA-DIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
+ F ++L G+A ++ I L+ +Y+FT+EFGL ++ G +YGAG+LSS E +
Sbjct: 141 YVDFLEKLSGIALKHINNPWAIQLLSRIYWFTIEFGLIKE-GGELKIYGAGILSSAGETK 199
Query: 384 HALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQ 435
+L+ +D +++E +Q+ Y+ +++E+ E + E ++
Sbjct: 200 FSLSNEPNHIDYDVRRILNQEYWKDRFQDKYFVIENYEQLYESLPEIEEVLE 251
>UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=1; Psychroflexus torquis ATCC 700755|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Psychroflexus torquis ATCC 700755
Length = 242
Score = 107 bits (257), Expect = 7e-22
Identities = 67/231 (29%), Positives = 112/231 (48%), Gaps = 7/231 (3%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
+YT+ ++ W +F + A Y++ + D +P E ++S+ K +
Sbjct: 6 KYTKDDLWVWNTLFNRQKENIPGKASKSYIDALEHMSPVLN--ADEIPDFEKINSWFKTE 63
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
T ++L+ V G + +F LA R F + ++R Y EPD H++ GH+PLL++P
Sbjct: 64 TQWELQVVPGLIPVEEFFKLLAERKFCSSTWLRSKDSLDYLEEPDVFHDIFGHVPLLSDP 123
Query: 325 SFAQFSQE---LGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAE 381
F++F E LG LG ++ I +L LY+FT+EFG+ ++ GS YGAG+LSS E
Sbjct: 124 VFSEFVCEFGKLGCQFLGDTEKLI-QLQRLYWFTIEFGVIKE-QGSIQSYGAGILSSSGE 181
Query: 382 LQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAE 432
+ + +E Q YY SFE + ++A A+
Sbjct: 182 TNQIHEQKANFIDYSIQAIIEKEFRTDIMQEDYYVISSFEILFDSLKALAD 232
>UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19;
Vibrionaceae|Rep: Phenylalanine-4-hydroxylase - Vibrio
cholerae
Length = 289
Score = 107 bits (257), Expect = 7e-22
Identities = 69/213 (32%), Positives = 103/213 (48%), Gaps = 6/213 (2%)
Query: 204 VQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKR 263
+ + + E W + ++ + AC YL+ L D LPQL +++ L+R
Sbjct: 40 IDWDQDEHAVWHELITRQQEVVKTRACQAYLDGLNML----NLPTDRLPQLPEINRVLQR 95
Query: 264 KTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLAN 323
+TG+Q+ PV +S F + LA + F ++R + Y EPD HE+ GH +L +
Sbjct: 96 ETGWQVEPVPALISFDRFFALLADKKFPVATFLRRREEFDYLQEPDFFHEVYGHCAMLTH 155
Query: 324 PSFAQFSQELGLASLGASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQ 383
P FA F+ G A+ + LA LY+FTVEFGL Q G +YG G+LSS E
Sbjct: 156 PDFAAFTHVYGQLGAKATPKERSYLARLYWFTVEFGLV-QEQGQTKIYGGGILSSPGETL 214
Query: 384 HAL-TTPEKIKRFDPDITVHEECIITSYQNAYY 415
+A +T K + FD + I Q YY
Sbjct: 215 YASESTIPKREPFDIMQVLRTPYRIDIMQPIYY 247
>UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1;
Mesorhizobium loti|Rep: Phenylalanine-4-hydroxylase -
Rhizobium loti (Mesorhizobium loti)
Length = 275
Score = 107 bits (257), Expect = 7e-22
Identities = 70/222 (31%), Positives = 110/222 (49%), Gaps = 7/222 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
Y++ E W + KL +K A YL+ V+ G D +P EDVS+ L++ T
Sbjct: 34 YSDEEQAVWRTLCDRQTKLTRKLAHHSYLDG----VEKLGLL-DRIPDFEDVSTKLRKLT 88
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+++ V G + F LA R F T ++R + Y EPD H+ GH+P+L+ P
Sbjct: 89 GWEIIAVPGLIPAAPFFDHLANRRFPVTNWLRTRQELDYIVEPDMFHDFFGHVPVLSQPV 148
Query: 326 FAQFSQELGLASLGASDADIDKLAT-LYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQH 384
FA F Q G + D++ T LY++T E+GL ++ +GAGL+SS ELQ
Sbjct: 149 FADFMQMYGKKAGDIIALGGDEMITRLYWYTAEYGLVQEAGQPLKAFGAGLMSSFTELQF 208
Query: 385 ALTTPEKIK-RFDPDITVHEECIITSYQNAYYYTDSFEEAKE 425
A+ + FD + + I +Q AY+ SF+ ++
Sbjct: 209 AVEGKDAHHVPFDLETVMRTGYEIDKFQRAYFVLPSFDALRD 250
>UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Phenylalanine-4-hydroxylase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 293
Score = 107 bits (256), Expect = 9e-22
Identities = 79/251 (31%), Positives = 118/251 (47%), Gaps = 11/251 (4%)
Query: 178 DPIYRKRREQFAAIANNYKYGHPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENW 237
D + K R A A++Y Y+ E W +FR ++ A L+
Sbjct: 2 DTAFAKNRYHGAPRADDYTIDQAWET--YSPAEHDRWDRLFRRQKEIATGRASKVALDAM 59
Query: 238 PQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIR 297
+L +P + +S L++ TG+++ PVA + F LA R F +IR
Sbjct: 60 HKLE----LSPSGIPHMGRLSDKLEKITGWRVVPVAELVPDEVFFDHLANRRFPAGAFIR 115
Query: 298 HSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASD-ADIDKLATLYFFTV 356
+ Y EPD H++ GH+P+LA+P FA F + G A + LA LY++TV
Sbjct: 116 PEEEFDYLQEPDIFHDIFGHVPMLADPVFADFMEAYGKGGQRAMRLGQLHNLARLYWYTV 175
Query: 357 EFGLCRQPDGSFCVYGAGLLSSVAELQHAL--TTPEKIKRFDPDITVHEECIITSYQNAY 414
EFGL ++ DG +YGAG+LSS E AL +P +I FD + + II +Q Y
Sbjct: 176 EFGLIQEEDG-LRIYGAGILSSPHETVFALEDASPNRI-GFDLQRLMRTKYIIDDFQQTY 233
Query: 415 YYTDSFEEAKE 425
+ SFE E
Sbjct: 234 FVIPSFEALLE 244
>UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep:
Phenylalanine-4-hydroxylase - Oceanicaulis alexandrii
HTCC2633
Length = 370
Score = 103 bits (246), Expect = 1e-20
Identities = 72/248 (29%), Positives = 116/248 (46%), Gaps = 33/248 (13%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT E W ++F K+ AC +++E + QL +D +P +D+++ LK T
Sbjct: 65 YTPAEHARWRLLFENQRKMLPGRACKDFMEGFEQLEHLF---KDGIPSFDDINAILKPAT 121
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSS------------------------- 300
G+ + PV + F L R F +IR +
Sbjct: 122 GWTVVPVPELIPDNIFFWHLENRRFPAGVFIRGGNPKTKKVKEANEGRAPEFVEYTAVED 181
Query: 301 DPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDAD-IDKLATLYFFTVEFG 359
D FY EPD H++ GH+P+L NP FA + Q G A + + + ++Y++TVEFG
Sbjct: 182 DLFYLQEPDTFHDIFGHVPMLMNPFFADYIQAYGAGGRRAIEYNRLKNFGSVYWYTVEFG 241
Query: 360 LCRQPDGSFCVYGAGLLSSVAELQHAL--TTPEKIKRFDPDITVHEECIITSYQNAYYYT 417
L + +G VYGAG+LSS E +L +P +IK P+ + + +I+ +Q Y+
Sbjct: 242 LILE-EGELRVYGAGILSSPDETLFSLYSDSPHRIKMV-PERVMRTDYVISDFQETYFVV 299
Query: 418 DSFEEAKE 425
DS + E
Sbjct: 300 DSIKALYE 307
>UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna -
Bicyclus anynana (squinting bush brown)
Length = 125
Score = 103 bits (246), Expect = 1e-20
Identities = 45/99 (45%), Positives = 70/99 (70%)
Query: 371 YGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAF 430
+GAGLLSS ELQ+ L+ +++ +P +T ++ IT YQ Y+ SFE AKEKM F
Sbjct: 4 FGAGLLSSFGELQYCLSDKPELRESEPSVTGEQKYPITEYQPVYFVAQSFESAKEKMIKF 63
Query: 431 AESIQRPFGVRYNPYTQSVEVLSNAQKITALVSELRGDL 469
A++I R FGVRYNPYTQS+++L + +++T L+ ++R ++
Sbjct: 64 AQTIPREFGVRYNPYTQSIDILDSPRQMTDLLKQIRTEM 102
>UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1;
Solibacter usitatus Ellin6076|Rep: Aromatic amino acid
hydroxylase - Solibacter usitatus (strain Ellin6076)
Length = 306
Score = 102 bits (245), Expect = 2e-20
Identities = 74/238 (31%), Positives = 116/238 (48%), Gaps = 24/238 (10%)
Query: 202 PKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFL 261
P Y++ + W +F+ +H ++++A +L V+ D +P+L DV+ L
Sbjct: 32 PYELYSKENHEAWQKLFKRIHTRWERYANDHFLRG----VEALELPHDRVPRLTDVNRRL 87
Query: 262 KRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLL 321
+ TGFQ +PV+GY+ F L R F T IR + Y PEPD H++ GH+P+
Sbjct: 88 QPLTGFQAKPVSGYVPGFLFFDCLRRREFPTTITIRPADRMDYLPEPDIFHDVAGHVPMH 147
Query: 322 ANPSFAQFSQELG-----LASLGASDADIDK-----------LATLYFFTVEFGLCRQPD 365
FA G A + A D K ++ ++FTVEFGL R
Sbjct: 148 TERQFADTLVRFGDCAVTAARITAEVKDPAKRVRRLTSIMRAMSRFFWFTVEFGLMRGTK 207
Query: 366 GSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDI--TVHEECIITSYQNAYYYTDSFE 421
G+ YG+GLLSS EL+HA+ + E ++R+ + +++ I YQ + DSFE
Sbjct: 208 GT-VAYGSGLLSSYGELEHAIESDE-VQRYPIQLEWVINQVAEIDHYQPILFVVDSFE 263
>UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4;
Sphingomonadales|Rep: Phenylalanine-4-hydroxylase -
Erythrobacter sp. SD-21
Length = 313
Score = 99.1 bits (236), Expect = 2e-19
Identities = 67/240 (27%), Positives = 114/240 (47%), Gaps = 14/240 (5%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
Y + W +F+ ++ A ++E +L G +P+ +S L + T
Sbjct: 44 YDSEDDAIWNDLFKRQMEMLPGRAATAFMEGTEKLDLGRG----GVPEFGKLSEELDKLT 99
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+ + PV + F LA R F +IR Y EPD H++ GH+P+L +P
Sbjct: 100 GWSVVPVPMLIPDHVFFWHLANRRFPAGNFIRTRETFDYIQEPDVFHDVFGHVPMLTDPV 159
Query: 326 FAQFSQELGLASLGASDAD-IDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQH 384
+A + QE G A A + + L +LY++TVEFGL + G YGAG+LS E+ +
Sbjct: 160 YADYMQEYGKAGWKAMRYNRLKALGSLYWYTVEFGLIEEKPGDIRAYGAGILSGPTEVVY 219
Query: 385 AL--TTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRY 442
++ +P +I + D + + +I+ Q Y+ SFE+ F ++++R F Y
Sbjct: 220 SVEAESPNRI-MLNVDRVMRTDYVISDLQPTYFVIPSFED------LFRQTVERDFDKLY 272
>UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyces
verticillus|Rep: Amino acid hydroxylase - Streptomyces
verticillus
Length = 244
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/233 (27%), Positives = 100/233 (42%), Gaps = 9/233 (3%)
Query: 199 HPIPKVQ--YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLED 256
H +P VQ Y + + W ++R+ +L A P YLE L G D++P L
Sbjct: 4 HGVPPVQEPYGPVDQEVWRHLYRQQAELVPAAAPPLYLEGLALL----GLPTDHVPDLGQ 59
Query: 257 VSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLG 316
V+ L +G+ V G + +F L R F T +R + + PD H+L G
Sbjct: 60 VNERLSAVSGWTCVAVDGLVKGPEFFDMLLHRRFPVTSRMRAPEELRFARLPDLFHDLFG 119
Query: 317 HMPLLANPSFAQFSQELGLASL--GASDADIDKLATLYFFTVEFGLCRQPDGSFCVYGAG 374
H P LA+ A QE G + D L + + T+E GL R P G G
Sbjct: 120 HGPYLAHARTADLYQEFGRIGVRCAGRPEDFALLQGILWSTLETGLIRTP-GGLRALGGA 178
Query: 375 LLSSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKM 427
+LSS E++ L ++ FDP++ I Q+ Y+ + EE + +
Sbjct: 179 ILSSADEIRQCLDPACPVEPFDPEVVRFATYDILRLQSRYFAVEDLEEIESAL 231
>UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep:
Phenylalanine-4-hydroxylase - Cytophaga hutchinsonii
(strain ATCC 33406 / NCIMB 9469)
Length = 246
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/227 (23%), Positives = 108/227 (47%), Gaps = 12/227 (5%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YTE E K W + + A + ++ G D +P +E+++ L + T
Sbjct: 15 YTEEENKIWATAYSRILNFLGDVADESVMIG----IRTIGLPGDRVPNVEEINEHLAKHT 70
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSD-PFYTPEPDCCHELLGHMPLLANP 324
+++ P+ + F+S LA +++ C ++R E D H++ GH LL P
Sbjct: 71 DWRIVPLEDMVDDTQFISMLADKLYPCRTWVRSIDQVDKMEDEYDIFHDVFGHTSLLYIP 130
Query: 325 SFAQFSQELG-LASLGASDAD-IDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAEL 382
++ + ++LG LA +D I L +Y+ T+++GL + + S +YGA +++S E
Sbjct: 131 TYCLYLEQLGELALTYINDPKAILYLKRVYWHTIQYGLI-EANKSLRIYGAHMITSRNEA 189
Query: 383 QHALTTPEKIKRFDPDITVHEEC--IITSYQNAYYYTDSFEEAKEKM 427
+AL + ++D ++++ + + +Q Y+ S+E+ M
Sbjct: 190 SYALNA--GVPKYDHNVSIIMDTPYVKNHFQEKYFVISSYEQLLASM 234
>UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase
biopterin-dependent; n=3; Chlamydophila|Rep: Aromatic
amino acid hyroxylase biopterin-dependent -
Chlamydophila felis (strain Fe/C-56)
Length = 279
Score = 72.5 bits (170), Expect = 2e-11
Identities = 53/210 (25%), Positives = 93/210 (44%), Gaps = 21/210 (10%)
Query: 255 EDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHEL 314
+ ++S + ++GF L P GYLSP ++L L+ + F +R + ++ PD H+L
Sbjct: 53 DHINSVISSQSGFTLSPTQGYLSPHNYLFELSQKRFPIATNVRSLEEDGFSTLPDLIHDL 112
Query: 315 LGHMPLLANPSFAQFSQELG---LASLGAS-------------DADIDKLATLYFFTVEF 358
H+P L +P F F +G + S+ + +++ ++ ++FTVE
Sbjct: 113 FCHIPWLLHPEFVNFFSTMGELFVKSIKRAKEIYPIEDQPRILNSNALAISRCFWFTVES 172
Query: 359 GLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECIITSYQNAYYYTD 418
GL + G YGA +LSS +L H + F + + C + Q +
Sbjct: 173 GLIEE-QGKRKAYGAAVLSSTEQLSHTFNNNVFVSPFKTEHIIQRPCNPNAIQTTLFIIR 231
Query: 419 SFEEAKE---KMRAFAESIQRPFGVRYNPY 445
F E + KM F E + F V + P+
Sbjct: 232 DFSELNDISKKMHLFLEKGRLDF-VVFGPH 260
>UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1;
Bdellovibrio bacteriovorus|Rep: Putative uncharacterized
protein - Bdellovibrio bacteriovorus
Length = 580
Score = 71.7 bits (168), Expect = 4e-11
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 9/145 (6%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
+YT + W V R+L KHA Y+E + G + +P++EDVS ++ +
Sbjct: 21 KYTPVDQAVWRYVLRQLKAFLSKHAHECYVEG----LNKTGIDIERIPRIEDVSKKIQ-E 75
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
G++ PV+G++ P F+ + V +R YTP PD HE GH P+L +P
Sbjct: 76 FGWRALPVSGFIPPAAFMELQSLGVLPIASDMRTLDHLLYTPAPDIVHEAAGHAPILIHP 135
Query: 325 SFA----QFSQELGLASLGASDADI 345
F+ Q++Q A + D D+
Sbjct: 136 EFSDYLRQYAQVAKKAIISKEDLDL 160
Score = 37.9 bits (84), Expect = 0.62
Identities = 25/68 (36%), Positives = 43/68 (63%), Gaps = 7/68 (10%)
Query: 343 ADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVH 402
++ +L+ + ++T E+GL + D ++GAGLLSSV E + L+ +K+K+ +TV
Sbjct: 199 SEASELSRMNWWTAEYGLIGELDNPK-IFGAGLLSSVGESKWCLS--QKVKKI--PLTV- 252
Query: 403 EECIITSY 410
+CI TSY
Sbjct: 253 -DCIKTSY 259
>UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylase;
n=2; Chlamydophila pneumoniae|Rep: Probable aromatic
amino acid hydroxylase - Chlamydia pneumoniae
(Chlamydophila pneumoniae)
Length = 362
Score = 71.7 bits (168), Expect = 4e-11
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 21/215 (9%)
Query: 227 KHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKTGFQLRPVAGYLSPRDFLSGLA 286
K CP + ++ ++ G D L + V F + +T F PV+G+++P +LS L
Sbjct: 119 KSYCPRFFLDY---LEAFGLLSDFLDH-QAVIKFFELETHFSYYPVSGFVAPHQYLSLLQ 174
Query: 287 FRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELG------LASLGA 340
R F +R ++ PD H+LLGH+P L +PSF++F +G + + A
Sbjct: 175 DRYFPIASVMRTLDKDNFSLTPDLIHDLLGHVPWLLHPSFSEFFINMGRLFTKVIEKVQA 234
Query: 341 SDADIDKLATL----------YFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPE 390
+ ++ TL ++FTVE GL +G YGA L+SS EL HA
Sbjct: 235 LPSKKQRIQTLQSNLIAIVRCFWFTVESGLIENHEGR-KAYGAVLISSPQELGHAFIDNV 293
Query: 391 KIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKE 425
++ + D + ++ Q + F+E E
Sbjct: 294 RVLPLELDQIIRLPFNTSTPQETLFSIRHFDELVE 328
>UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1;
Congregibacter litoralis KT71|Rep: Putative
uncharacterized protein - Congregibacter litoralis KT71
Length = 596
Score = 66.1 bits (154), Expect = 2e-09
Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 5/139 (3%)
Query: 202 PKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFL 261
P QYT + W + L + + A P YLE + G D++P ++++++ L
Sbjct: 28 PDAQYTPRDHAVWRFLMTALTRGLAQTAHPVYLEG----LSRTGIALDHIPSIDEMNACL 83
Query: 262 KRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLL 321
K G++ V G++ P F+ A +V +R YTP PD HE GH P L
Sbjct: 84 A-KLGWRAVVVDGFIPPAIFMEFQALKVLVIALDMRSVEHLLYTPAPDILHESAGHAPFL 142
Query: 322 ANPSFAQFSQELGLASLGA 340
+ +A+F Q G + A
Sbjct: 143 VDVDYAEFLQRFGEVGMQA 161
Score = 46.8 bits (106), Expect = 0.001
Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 332 ELGLASLGASDADIDK---LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTT 388
E LA+LG SD + + L L+++TVE+GL + + + ++GAGLLSS+ E Q L
Sbjct: 195 EARLAALGDSDGEPSEAALLTRLHWWTVEYGLVGELE-DYRLFGAGLLSSLGESQSCL-D 252
Query: 389 PEKIKRFDPDI-TVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESI 434
E++K+ + V ITS Q + T S + + FA ++
Sbjct: 253 DERVKKLPLTVNAVETPYDITSTQPQLFVTKSCRHMSQVLEEFAATM 299
>UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5;
Cystobacterineae|Rep: Aromatic amino acid hydroxylase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 61.3 bits (142), Expect = 6e-08
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT + W + R L + A P YL ++ G + +P+L++++ L R
Sbjct: 27 YTPRDHAVWRHILRRLTAHLRSRAHPRYLAG----LEATGIDVERIPRLDEMNERLAR-A 81
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+ V G++ P F + RV IR YTP PD HE GH P +A+P+
Sbjct: 82 GWAAVAVRGFIPPAVFTELQSRRVLAIAADIRTHEHIEYTPAPDIVHESAGHAPFIADPT 141
Query: 326 FAQFSQELG 334
+A++ + G
Sbjct: 142 YAEYLRRAG 150
Score = 39.1 bits (87), Expect = 0.27
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 319 PLLANPSFAQFSQELGLASLGASDA-DIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLS 377
P A Q L A+ A + + + LY++T E+GL D +YGAGLLS
Sbjct: 179 PTAGEEEVALAEQRLAAAAASVRYASESTRASRLYWWTAEYGLVGALDAPR-LYGAGLLS 237
Query: 378 SVAELQHALT-TPEKIKRFDPDITVHEECIITSYQNAYYYTDSFEEAKEKMRAFAESI 434
S+ E H LT EK+ + + IT Q + F++ E + FA ++
Sbjct: 238 SIGEAVHCLTPAVEKLPLTAACADLAYD--ITRMQPQLFVARDFDQLFEVLDGFAATL 293
>UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13;
Bacteroidetes|Rep: Phenylalanine 4-monooxygenase -
Croceibacter atlanticus HTCC2559
Length = 586
Score = 60.9 bits (141), Expect = 8e-08
Identities = 42/143 (29%), Positives = 66/143 (46%), Gaps = 7/143 (4%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT W V R+ + K A YL +K G + +P + ++ LK
Sbjct: 30 YTAINQAVWRYVMRKNVEYLGKVAHESYLSG----LKKTGISINEIPSMYGMNRILK-DI 84
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+ V G++ P F+ A++V IR + YTP PD HE GH P++A+P
Sbjct: 85 GWAAVAVDGFIPPNAFMEFQAYKVLVIASDIRQLENIEYTPAPDIIHEGAGHAPIIASPD 144
Query: 326 FAQFSQELG-LASLGASDA-DID 346
+A++ + G + S S A DI+
Sbjct: 145 YAEYLRRFGEIGSKAISSAHDIE 167
Score = 44.8 bits (101), Expect = 0.005
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 343 ADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVH 402
++I + L+++TVE+GL + +YGAGLLSS+ E ++ +T K + D +
Sbjct: 207 SEISLIRNLHWWTVEYGLVGTVEDPK-IYGAGLLSSIGESKNCMTDAVKKIPYSID-AAY 264
Query: 403 EECIITSYQNAYYYTDSFEEAKEKMRAFAESI 434
++ IT Q + T F +E + FA ++
Sbjct: 265 QDFDITKQQPQLFVTPDFAYLQEVLEEFANTM 296
>UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1;
Exiguobacterium sibiricum 255-15|Rep: Aromatic amino
acid hydroxylase - Exiguobacterium sibiricum 255-15
Length = 548
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT T+ W V R K Q A P YLE + G + +P + ++++ L R
Sbjct: 22 YTPTDHAVWRYVMRLNLKTLQDTAHPAYLEG----LAASGISPERIPDVREMTANLSRG- 76
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+ V G + F + IR + YTP PD HE GH P+L NP+
Sbjct: 77 GWGTVAVDGLIPGVAFFDFQGHGLLPIATDIRKVDNILYTPAPDILHEAAGHAPILMNPT 136
Query: 326 FAQFSQELG 334
+A+F + G
Sbjct: 137 YAEFVRRFG 145
Score = 56.4 bits (130), Expect = 2e-06
Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 343 ADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVH 402
++ ++++ L+++TVEFGL D +YGAGLLSSV E +H LT F +
Sbjct: 199 SEANEISRLFWWTVEFGLIGDLDNPQ-IYGAGLLSSVGESRHCLTDAVVKHPFSLAKALA 257
Query: 403 EECIITSYQNAYYYTDSFEEAKEKMRAFAESI 434
+ +TS Q + +SFE+ +E + FA+++
Sbjct: 258 TKHDVTSMQKELFVCESFEQLREALEEFAQTM 289
>UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative;
n=10; Bacillus cereus group|Rep:
Phenylalanine-4-hydroxylase, putative - Bacillus
anthracis
Length = 584
Score = 55.6 bits (128), Expect = 3e-06
Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 1/92 (1%)
Query: 343 ADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVH 402
++ ++++ L+++TVE+GL D +YGAGLLSSV E +H LT + F +
Sbjct: 200 SEAEQISRLFWWTVEYGLIGDIDNPK-IYGAGLLSSVGESKHCLTDAVEKVPFSIEACTS 258
Query: 403 EECIITSYQNAYYYTDSFEEAKEKMRAFAESI 434
+T Q + SFEE E + FAE++
Sbjct: 259 TTYDVTKMQPQLFVCKSFEELTEALEKFAETM 290
Score = 54.0 bits (124), Expect = 9e-06
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 5/130 (3%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
QYT W + R+ H + A P Y+ ++ G + +P++E+++ L
Sbjct: 22 QYTPVNHAVWRYIMRQNHSFLKDVAHPAYVNG----LQSSGINIEAIPKVEEMNECLA-S 76
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
+G+ + G + F + IR + YTP PD HE GH P+L +P
Sbjct: 77 SGWGAVTIDGLIPGVAFFDFQGHGLLPIATDIRKVENIEYTPAPDIVHEAAGHAPILLDP 136
Query: 325 SFAQFSQELG 334
++A++ + G
Sbjct: 137 TYAKYVKRFG 146
>UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1;
Bacillus sp. SG-1|Rep: Phenylalanine 4-monooxygenase -
Bacillus sp. SG-1
Length = 642
Score = 55.2 bits (127), Expect = 4e-06
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 206 YTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRKT 265
YT W V R+ H + A P +L+ +K G + +P++ +++ L R
Sbjct: 88 YTPVNHAVWRYVMRQNHAFLEDRAHPAFLKG----LKGSGIAIEKIPRVSEMNEALGR-I 142
Query: 266 GFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANPS 325
G+ V G + F A + IR S+ YTP PD HE GH P+L + +
Sbjct: 143 GWGAVIVDGLIPGTAFFDLQAHGLLPIATDIRKVSNIEYTPAPDILHEAAGHAPILFDST 202
Query: 326 FAQFSQELG 334
+++F +++G
Sbjct: 203 YSEFVKKIG 211
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/98 (36%), Positives = 59/98 (60%), Gaps = 11/98 (11%)
Query: 342 DADIDKLATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITV 401
+++ ++++ L+++TVEFGL + + VYGAGLLSSV E + L+ +++K+ I
Sbjct: 264 NSEAEQISRLFWWTVEFGLIGKVEKPM-VYGAGLLSSVGESKACLS--DQVKKIPFSI-- 318
Query: 402 HEECIITSY-----QNAYYYTDSFEEAKEKMRAFAESI 434
EECI TSY Q + +SFEE E + F+ S+
Sbjct: 319 -EECIKTSYDVTTMQKQLFVCESFEELIEAVEEFSASM 355
>UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1;
Pedobacter sp. BAL39|Rep: Phenylalanine-4-hydroxylase -
Pedobacter sp. BAL39
Length = 594
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 7/136 (5%)
Query: 205 QYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVSSFLKRK 264
+YT + W V R+ + ++ A Y++ ++ G + +P L+ ++ L K
Sbjct: 30 KYTPIDQAVWRYVMRQNYSYLKQVAFYPYIKG----LQRAGLSIEYIPDLQTMNDNLG-K 84
Query: 265 TGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANP 324
G+ V G++ P F+ A+ V IR + YTP PD HE GH P++A+
Sbjct: 85 IGWGAVTVDGFIPPAAFMEYQAYHVLVIAADIRQINHIQYTPAPDIIHESAGHAPIIADA 144
Query: 325 SFAQFSQELGLASLGA 340
+ + G S+GA
Sbjct: 145 DYNSYLSYFG--SIGA 158
Score = 37.9 bits (84), Expect = 0.62
Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 348 LATLYFFTVEFGLCRQPDGSFCVYGAGLLSSVAELQHALTTPEKIKRFDPDITVHEECII 407
L L+++TVE+GL + +YGAGLLSS+ E + + + D ++ I
Sbjct: 213 LGRLHWWTVEYGLIGTLEDPK-IYGAGLLSSIGESSSCMKSDVPKLPYTID-AINHPYDI 270
Query: 408 TSYQNAYYYTDSFEEAKEKMRAFAESI 434
T Q + T++F+ + + FA+++
Sbjct: 271 TKTQPQLFVTETFQNLIDVLEQFADTM 297
>UniRef50_O67085 Cluster: P-protein [Includes: Chorismate mutase (EC
5.4.99.5) (CM); Prephenate dehydratase (EC 4.2.1.51)
(PDT)]; n=10; Bacteria|Rep: P-protein [Includes:
Chorismate mutase (EC 5.4.99.5) (CM); Prephenate
dehydratase (EC 4.2.1.51) (PDT)] - Aquifex aeolicus
Length = 362
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 2/78 (2%)
Query: 46 SERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE--CDPQR 103
S++ S++F +K++ G L +AL VF GIN+ IESR S + VD+E + +R
Sbjct: 275 SDKTSILFGVKDEPGALYKALEVFYKHGINLTKIESRPSKKKAWDYVFFVDLEGHKEEER 334
Query: 104 MEQLKRMLKREVQDFEVV 121
+E+ + LK + Q +V+
Sbjct: 335 VEKALKELKEKTQFLKVL 352
>UniRef50_Q751Q3 Cluster: AGL364Cp; n=1; Eremothecium gossypii|Rep:
AGL364Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1260
Score = 44.4 bits (100), Expect = 0.007
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 26 SPHHPKLGELHAARVQAQAESERISV---MFTLKNQVGGLVRALSVFQDLGINVLHIESR 82
S HH KL E + A + Q +S+ +S + +L + V GL R L S
Sbjct: 637 SKHHRKLHETYPAPLDEQTDSKDLSAPSPVLSLASNVVGLQRRKPSTSTWDTKALPENSS 696
Query: 83 KSMTEVSSADILVDVECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFD 142
KS + +S +++ + E Q E L + E ++ + P T PPP P+S +A+
Sbjct: 697 KSDSSAASPNLITNEERTLQSPEALSEI--EEKKEIGLASPMTPPPPPPPLPISLSATGS 754
Query: 143 F 143
F
Sbjct: 755 F 755
>UniRef50_Q8RB13 Cluster: Prephenate dehydratase; n=3;
Thermoanaerobacter|Rep: Prephenate dehydratase -
Thermoanaerobacter tengcongensis
Length = 283
Score = 41.9 bits (94), Expect = 0.038
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQ 106
++ S++F++ N G L RAL VF + IN+ IESR S + VD+E ++ E+
Sbjct: 197 DKTSIVFSVPNVPGSLYRALGVFAEKNINMTKIESRPSRKKFGEYVFWVDIE-GHRKEER 255
Query: 107 LKRMLK 112
+K L+
Sbjct: 256 IKEALE 261
>UniRef50_Q58054 Cluster: Prephenate dehydratase; n=26;
Euryarchaeota|Rep: Prephenate dehydratase -
Methanococcus jannaschii
Length = 272
Score = 40.3 bits (90), Expect = 0.12
Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Query: 48 RISVMFTLK-NQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQ 106
++S++F LK ++ G L L F + IN+ IESR S + + +D E + +++E+
Sbjct: 191 KVSIVFELKEDKPGALYHILKEFAERNINLTRIESRPSKKRLGTYIFYIDFENNKEKLEE 250
Query: 107 LKRMLKR 113
+ + L+R
Sbjct: 251 ILKSLER 257
>UniRef50_UPI00003C844A Cluster: hypothetical protein Faci_03000293;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000293 - Ferroplasma acidarmanus fer1
Length = 270
Score = 39.9 bits (89), Expect = 0.15
Identities = 24/100 (24%), Positives = 51/100 (51%), Gaps = 2/100 (2%)
Query: 22 VKNESPHHPKLGELHAARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIES 81
++N + + + A V+A A S + S++F+ +N+ G L + L + D GIN+ IES
Sbjct: 161 IENNRHSYTRFFLIAKAPVKASAPS-KTSIVFSTRNKPGALYKILKILNDYGINMTKIES 219
Query: 82 RKSMTEVSSADILVDVECDPQRMEQLKRMLKREVQDFEVV 121
R +D+E + + + +++ V+ F+++
Sbjct: 220 RPVQYIPFQYIFFIDIE-NNKNTDAAITDIQKSVEQFKIL 258
>UniRef50_P96240 Cluster: POSSIBLE PREPHENATE DEHYDRATASE PHEA;
n=20; Corynebacterineae|Rep: POSSIBLE PREPHENATE
DEHYDRATASE PHEA - Mycobacterium tuberculosis
Length = 321
Score = 39.1 bits (87), Expect = 0.27
Identities = 21/55 (38%), Positives = 32/55 (58%)
Query: 42 AQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVD 96
A+ ++R S + + NQ G LV AL+ F GI++ IESR + TE+ + VD
Sbjct: 195 ARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTELGTYLFFVD 249
>UniRef50_Q6PBJ4 Cluster: Zgc:73377; n=2; Danio rerio|Rep: Zgc:73377
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 148
Score = 38.7 bits (86), Expect = 0.35
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
Query: 24 NESPHHPKLGELHAARVQAQAESERISVMFTLKNQVGGLVRALSVFQ--DLGINVLHIES 81
N H P G A + Q R++V + K L R L V + D G++ L++
Sbjct: 11 NNKIHSPNRGASREAGLSVQKRQARVTVKYNRKE----LQRRLDVEKWIDCGLDELYLGR 66
Query: 82 RKSMTEVSSADILVDVECDPQRMEQLKRML 111
M E + D L+D++ D +R ++LK +L
Sbjct: 67 EDEMPEEVNIDELLDLQSDEERTQKLKDIL 96
>UniRef50_Q3AMU0 Cluster: Prephenate dehydratase; n=21;
Cyanobacteria|Rep: Prephenate dehydratase -
Synechococcus sp. (strain CC9605)
Length = 291
Score = 38.7 bits (86), Expect = 0.35
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 39 RVQAQAESERISVMFTL-KNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDV 97
R Q + S+ F+L +N G L+ AL+ + G+N+ IESR S E+ VDV
Sbjct: 194 RGQRSEHGDVASLAFSLHRNAPGALLEALACLAERGLNMSRIESRPSKRELGEYVFFVDV 253
Query: 98 ECDPQRMEQLKRML 111
+ P L+ ++
Sbjct: 254 DLPPDPSTALQDLI 267
>UniRef50_Q1AWL9 Cluster: Prephenate dehydratase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Prephenate dehydratase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 371
Score = 38.7 bits (86), Expect = 0.35
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQ 106
++ SV+F++K++ G L ALS F + GIN+ IESR S + D + P+ E+
Sbjct: 283 DKTSVVFSVKDRPGVLRDALSAFAEEGINLTRIESRPSRKRAWTYVFFADFQGHPEE-ER 341
Query: 107 LKRMLK 112
+ R L+
Sbjct: 342 VGRALE 347
>UniRef50_Q0AYS3 Cluster: Prephenate dehydratase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Prephenate dehydratase - Syntrophomonas wolfei subsp.
wolfei (strain Goettingen)
Length = 278
Score = 38.7 bits (86), Expect = 0.35
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 43 QAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQ 102
+ E E+ S++FTL ++ G L L +F +N+ IESR S ++VE
Sbjct: 183 KVEEEKSSIIFTLPDRPGALYHTLEIFNRRNLNLSKIESRPKKLLKGSYSFYIEVENGSN 242
Query: 103 RM---EQLKRMLKR 113
R+ E L+ + KR
Sbjct: 243 RVGIEELLEELQKR 256
>UniRef50_A1VGC5 Cluster: Chorismate mutase; n=4;
Deltaproteobacteria|Rep: Chorismate mutase -
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Length = 391
Score = 38.7 bits (86), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%)
Query: 43 QAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECD 100
Q E+ S++F+L ++ G L L + GIN+ +ESR E VDVECD
Sbjct: 282 QQGREKTSMLFSLPDKAGALAGVLELLAREGINMKKLESRPLRGEKWQYVFFVDVECD 339
>UniRef50_Q8KBW6 Cluster: Prephenate dehydratase; n=8;
Chlorobiaceae|Rep: Prephenate dehydratase - Chlorobium
tepidum
Length = 280
Score = 38.3 bits (85), Expect = 0.47
Identities = 19/56 (33%), Positives = 31/56 (55%)
Query: 29 HPKLGELHAARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKS 84
H ++ +V+ ++ S++F L N+ G L RAL+ F GI++ IESR S
Sbjct: 178 HENNPDISHLKVRPDVARQKTSIVFALPNEQGSLFRALATFALRGIDLTKIESRPS 233
>UniRef50_A6DR92 Cluster: Chorismate mutase/prephenate dehydratase;
n=1; Lentisphaera araneosa HTCC2155|Rep: Chorismate
mutase/prephenate dehydratase - Lentisphaera araneosa
HTCC2155
Length = 360
Score = 38.3 bits (85), Expect = 0.47
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVD 96
++ S++F LK++VG L+ L+ F G+N+ IESR + T VD
Sbjct: 272 DKTSIVFALKDKVGALMECLAAFGTQGVNMSMIESRPAKTHQGEYLFFVD 321
>UniRef50_UPI00015BC788 Cluster: UPI00015BC788 related cluster; n=1;
unknown|Rep: UPI00015BC788 UniRef100 entry - unknown
Length = 356
Score = 37.9 bits (84), Expect = 0.62
Identities = 19/52 (36%), Positives = 29/52 (55%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
++ S++ +KNQ G L +AL +F IN+ IESR S + VD+E
Sbjct: 275 DKTSIIMGVKNQTGALYKALEIFYRHNINLTKIESRPSKKKAWDDIFYVDME 326
>UniRef50_Q0AQ04 Cluster: Prephenate dehydratase; n=1; Maricaulis
maris MCS10|Rep: Prephenate dehydratase - Maricaulis
maris (strain MCS10)
Length = 384
Score = 37.9 bits (84), Expect = 0.62
Identities = 20/51 (39%), Positives = 30/51 (58%)
Query: 48 RISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
+ S+MFT ++ G LV AL F+D GIN++ +ESR ++DVE
Sbjct: 294 KTSMMFTTRDTPGSLVNALIGFRDNGINLVKLESRPIAGNPWEEMFIMDVE 344
>UniRef50_A6G281 Cluster: Chorismate mutase/prephenate dehydratase;
n=1; Plesiocystis pacifica SIR-1|Rep: Chorismate
mutase/prephenate dehydratase - Plesiocystis pacifica
SIR-1
Length = 372
Score = 37.9 bits (84), Expect = 0.62
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 38 ARVQAQAESE-RISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVD 96
AR AQ E + S+ FT+++ G LV LS F G+N+ HI+ R S E + VD
Sbjct: 276 AREAAQPSGEDKTSLSFTIQDGSGTLVDVLSCFASEGVNLSHIDKRPSGLENWTYSFFVD 335
Query: 97 VECDPQRMEQLKRMLKR 113
+ L+R L+R
Sbjct: 336 ALAH-REDANLQRALER 351
>UniRef50_Q8TZ60 Cluster: Prephenate dehydratase; n=1; Methanopyrus
kandleri|Rep: Prephenate dehydratase - Methanopyrus
kandleri
Length = 270
Score = 37.9 bits (84), Expect = 0.62
Identities = 19/60 (31%), Positives = 33/60 (55%)
Query: 39 RVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
R +A + ++ SV+F++ ++ G L L +F D GIN+ IESR + + +D E
Sbjct: 178 RDRAPTKEDKTSVVFSVTDRPGALREILGIFADRGINLTKIESRPAKRGLGDYVFFLDFE 237
>UniRef50_Q2FQ53 Cluster: Prephenate dehydratase; n=2;
Methanomicrobiales|Rep: Prephenate dehydratase -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 264
Score = 37.9 bits (84), Expect = 0.62
Identities = 18/57 (31%), Positives = 33/57 (57%)
Query: 56 KNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQLKRMLK 112
+N+ G L LS F++ G+N+ IESR S + + +D++C+ + E + R+ K
Sbjct: 189 ENRAGLLYDLLSPFKETGVNLTRIESRPSKRCMGNYVFFIDLQCEGEWKEAIDRIRK 245
>UniRef50_Q187E6 Cluster: P-protein [includes: chorismate mutase and
prephenate dehydratase]; n=4; cellular organisms|Rep:
P-protein [includes: chorismate mutase and prephenate
dehydratase] - Clostridium difficile (strain 630)
Length = 398
Score = 37.5 bits (83), Expect = 0.82
Identities = 18/61 (29%), Positives = 32/61 (52%)
Query: 39 RVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
++ + ES ++SV+F+++++ G L + L F IN+ IESR +D E
Sbjct: 306 QIHIEEESNKMSVVFSVEHEAGKLYKVLGYFAKNNINMTKIESRPMKNASWRYFFYIDFE 365
Query: 99 C 99
C
Sbjct: 366 C 366
>UniRef50_A0UXB4 Cluster: Prephenate dehydratase; n=2;
Clostridium|Rep: Prephenate dehydratase - Clostridium
cellulolyticum H10
Length = 280
Score = 37.5 bits (83), Expect = 0.82
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE--CDPQRM 104
++ S++F+ N+ G L R L +F IN+ IESR S + +D++ + Q +
Sbjct: 192 DKTSIVFSTDNKPGSLYRILDIFSLWDINMTRIESRPSKNALGQYIFFIDIDGHIEDQDV 251
Query: 105 EQLKRMLKREVQDFEVV 121
M+KR+ + +
Sbjct: 252 FDALTMIKRKTSFYRFI 268
>UniRef50_P10341 Cluster: Prephenate dehydratase; n=4;
Corynebacterium|Rep: Prephenate dehydratase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 315
Score = 37.5 bits (83), Expect = 0.82
Identities = 20/45 (44%), Positives = 27/45 (60%)
Query: 38 ARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESR 82
A V +R SV+F+L N G LVRAL+ F G+++ IESR
Sbjct: 192 AAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESR 236
>UniRef50_Q1GS18 Cluster: Threonine dehydratase; n=19;
Proteobacteria|Rep: Threonine dehydratase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 416
Score = 37.1 bits (82), Expect = 1.1
Identities = 16/69 (23%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 44 AESERIS-VMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQ 102
A S RI+ + L+++ G L + + +F + +N++ I ++ T + + ++ D+EC+ +
Sbjct: 332 ARSGRIARLRIRLQDRPGALFKVMKLFDEKQVNIIEIYHQRIFTTLPAKGLITDIECEAR 391
Query: 103 RMEQLKRML 111
E L ++
Sbjct: 392 DREHLDSLV 400
>UniRef50_Q6L0A4 Cluster: Prephenate dehydratase; n=1; Picrophilus
torridus|Rep: Prephenate dehydratase - Picrophilus
torridus
Length = 266
Score = 37.1 bits (82), Expect = 1.1
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 47 ERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRMEQ 106
++ S+ F+L+N+ G L R L++ IN+ IESR S +D E D
Sbjct: 181 DKYSIGFSLENRPGSLSRILNIISAFNINMTKIESRPYAKNPFSYIFFIDFE-DNGYGNV 239
Query: 107 LKRMLKREVQDFEVV 121
L ++KRE +F+++
Sbjct: 240 LIDIIKRETINFKLI 254
>UniRef50_A2SR16 Cluster: Prephenate dehydratase; n=2;
Methanomicrobiales|Rep: Prephenate dehydratase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 265
Score = 37.1 bits (82), Expect = 1.1
Identities = 23/91 (25%), Positives = 39/91 (42%)
Query: 22 VKNESPHHPKLGELHAARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIES 81
++N + + E+ A + + V+ +N+ G L L +F GIN+ IES
Sbjct: 159 IQNSLNNTTRFLEISAGALDPDDPEKCSVVIIPRENRPGLLYGILGIFAQRGINLTRIES 218
Query: 82 RKSMTEVSSADILVDVECDPQRMEQLKRMLK 112
R S + +D E DP E + + K
Sbjct: 219 RPSKEGIGRYVFFIDFETDPGWQETITELKK 249
>UniRef50_Q9WY02 Cluster: Chorismate mutase/prephenate dehydratase;
n=4; Thermotoga|Rep: Chorismate mutase/prephenate
dehydratase - Thermotoga maritima
Length = 353
Score = 36.7 bits (81), Expect = 1.4
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 39 RVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
R + E + S+ F ++++ G L L +F GIN+ +ESR + T + V+VE
Sbjct: 260 RKTGKMEGKYTSLFFGVQDRPGSLKAVLDIFASRGINLRKLESRPARTFLGDYVFFVEVE 319
Query: 99 CDPQRMEQLKRMLKREVQDFEVV 121
P + E + R L+R ++++
Sbjct: 320 A-PLKEEDI-RDLERVTAFYKII 340
>UniRef50_A3EWC2 Cluster: Prephenate dehydratase; n=1;
Leptospirillum sp. Group II UBA|Rep: Prephenate
dehydratase - Leptospirillum sp. Group II UBA
Length = 365
Score = 36.7 bits (81), Expect = 1.4
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 43 QAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQ 102
+ ++ S+M ++ ++VG L L + GINV +ESR S + +D+E Q
Sbjct: 268 KTRKDQTSIMISIIDRVGALSSILDMIAKQGINVTRLESRPSRKKAWDYIFFIDIE-GHQ 326
Query: 103 RMEQLKRMLKR 113
+ ++ +LK+
Sbjct: 327 EDQSIRELLKK 337
>UniRef50_A6NXG7 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 389
Score = 36.3 bits (80), Expect = 1.9
Identities = 17/40 (42%), Positives = 26/40 (65%)
Query: 43 QAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESR 82
++E +IS +FTL +Q G L L++F +N+L IESR
Sbjct: 297 RSERNKISALFTLPHQSGSLHEILTIFAVQNLNLLKIESR 336
>UniRef50_P73081 Cluster: Sll1939 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Sll1939 protein - Synechocystis sp.
(strain PCC 6803)
Length = 214
Score = 35.9 bits (79), Expect = 2.5
Identities = 25/111 (22%), Positives = 45/111 (40%), Gaps = 3/111 (2%)
Query: 103 RMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEM---PWFPRKISDLDRA 159
R E ++ + K Q +++ P G E +P + D GE+ PW R + ++
Sbjct: 102 RDESMEELTKMADQSWQLKVPTAGQEQSLQSPRRRVSPSDPGELEPLPWHHRALGNIQHP 161
Query: 160 QNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKVQYTETE 210
+ GS + + P ++P EQF I + + V +TE
Sbjct: 162 NQENLKGSNVSEEGPVTRNPGPAPSIEQFIPITQESNFLSRLQSVLSQDTE 212
>UniRef50_Q115I4 Cluster: TonB family protein; n=1; Trichodesmium
erythraeum IMS101|Rep: TonB family protein -
Trichodesmium erythraeum (strain IMS101)
Length = 537
Score = 35.9 bits (79), Expect = 2.5
Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
Query: 97 VECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSA--AASFDFGEMPWFPRKIS 154
VE P+++E+L + + E+ E+ P+ PPTP A E+P P S
Sbjct: 63 VELTPEQLERLPQPEEPEITFSEMPVPENFSPVAPPTPSEVPFVAEPPSSELPTIPLDPS 122
Query: 155 DLDRAQNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKYGHPIPKV 204
D + + + + L + P P + + ++ + + Y PIP +
Sbjct: 123 DYNLPELPPLDPTNLSSPLPSVSTPSVSRLPKN--SLPSEFSYNSPIPSI 170
>UniRef50_Q14246-2 Cluster: Isoform 2 of Q14246 ; n=3;
Homo/Pan/Gorilla group|Rep: Isoform 2 of Q14246 - Homo
sapiens (Human)
Length = 821
Score = 35.5 bits (78), Expect = 3.3
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 2/83 (2%)
Query: 300 SDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFG 359
+DP PE C+ +G+ NP F S L L AS DID+ + +
Sbjct: 177 ADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM--CPINST 234
Query: 360 LCRQPDGSFCVYGAGLLSSVAEL 382
P FC G S +L
Sbjct: 235 CTNTPGSYFCTCHPGFAPSNGQL 257
>UniRef50_Q5NLV8 Cluster: Prephenate dehydratase; n=8;
Sphingomonadales|Rep: Prephenate dehydratase - Zymomonas
mobilis
Length = 304
Score = 35.5 bits (78), Expect = 3.3
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 50 SVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDP 101
S++FT+KN L+ A+ F D +N+ +ES + S+ DVE +P
Sbjct: 221 SLLFTVKNTPSALLNAIKGFGDNQVNMTKLESYQHGASFSATQFYADVEGEP 272
>UniRef50_Q3ZZI7 Cluster: Chorismate mutase/prephenate dehydratase;
n=3; Dehalococcoides|Rep: Chorismate mutase/prephenate
dehydratase - Dehalococcoides sp. (strain CBDB1)
Length = 358
Score = 35.5 bits (78), Expect = 3.3
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 37 AARVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVD 96
A + A S++ SV+F +K+Q G L + GIN+ +ESR + + + +D
Sbjct: 262 AKQDSAPTGSDKTSVVFAVKHQAGALYDFIKELASRGINMTKLESRPTRLKPWEYNFYLD 321
Query: 97 VECDPQRMEQLKRMLKR 113
+E Q E +K+ L +
Sbjct: 322 IEGHRQD-ENVKQALAK 337
>UniRef50_Q13H21 Cluster: Putative FAD dependent oxidoreductase;
n=1; Burkholderia xenovorans LB400|Rep: Putative FAD
dependent oxidoreductase - Burkholderia xenovorans
(strain LB400)
Length = 442
Score = 35.5 bits (78), Expect = 3.3
Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Query: 199 HPIPKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLEDVS 258
+P P ++ I VF +L L HA ++ P LV R D++P L S
Sbjct: 334 NPSPDAEWPTRAIDHVAAVFPDLSGLRVAHAWAGAIDTTPDLVPVMS-RVDSMPGLVIAS 392
Query: 259 SFLKRKTGFQLRPVAGYLSPR---DFLSGLAFRVFHCTQY 295
F GF L P AG L R D +SG+ F T++
Sbjct: 393 GFSGH--GFGLGPGAGMLVSRIVTDDVSGIDLNPFRLTRF 430
>UniRef50_Q8RUZ5 Cluster: Putative uncharacterized protein
At2g40435; n=4; Magnoliophyta|Rep: Putative
uncharacterized protein At2g40435 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 158
Score = 35.5 bits (78), Expect = 3.3
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 52 MFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDPQRM--EQLKR 109
+F+ KNQ G LV L F+D+G+NVL E+R S T+ S + D + M E +K+
Sbjct: 84 VFSGKNQPGMLVSVLEAFEDIGLNVL--EARASCTDSFSLHAMGLENEDGENMDAEAVKQ 141
Query: 110 MLKREVQDF-EVVPPQ 124
+ ++ + E+ PQ
Sbjct: 142 AVTDAIRSWGEINDPQ 157
>UniRef50_Q4Q710 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 799
Score = 35.5 bits (78), Expect = 3.3
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 5/116 (4%)
Query: 77 LHIESRKSMTEVSS--ADILVDVECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTP 134
LH+E + M ++ AD E QR E+LKR L + Q + V D
Sbjct: 155 LHLEKEEVMQRIAKWEADQAQKAEEMRQREEELKRQLAAQQQREQEVKQHLSDLVEQQVS 214
Query: 135 MSAAASFDFGEMPWFPRKISDLDRAQNVLMYGSELDADHPG---FKDPIYRKRREQ 187
AA+ G+ P + A + Y DAD PG + + R+RR +
Sbjct: 215 QHVAAASATGKAAAAPTNTATHRTAAKAVEYDETEDADEPGTGVSRAELQRRRRRE 270
>UniRef50_Q6FPZ7 Cluster: Similar to sp|P53278 Saccharomyces
cerevisiae YGR130c; n=1; Candida glabrata|Rep: Similar
to sp|P53278 Saccharomyces cerevisiae YGR130c - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 813
Score = 35.5 bits (78), Expect = 3.3
Identities = 37/175 (21%), Positives = 62/175 (35%), Gaps = 6/175 (3%)
Query: 87 EVSSADILVDVECDPQRMEQLKRMLKREVQDFEVVPPQTGDEFPPPTPMSAAASFDFGEM 146
E +AD ++D E +P+ E++ +K ++ P P + E
Sbjct: 322 EAKAADAVMDSEAEPESQEKMAPSVKDTSSALASEDLESYMTVETPQPYDKVPRIPYTEQ 381
Query: 147 PWFPRKISDL----DRAQNVLMYGSELDADHPGFKDPIYRKRREQFAAIANNYKY-GHPI 201
P +K S D A + ++ + D PI + A Y Y PI
Sbjct: 382 PESGKKFSSFFKRNDNAGHPVITDVPVIPDQSQLDFPIATPENPELIAKTEEYGYMSKPI 441
Query: 202 -PKVQYTETEIKTWGIVFRELHKLYQKHACPEYLENWPQLVKYCGYREDNLPQLE 255
KV Y ET + W F++ K EY +L K +++ L+
Sbjct: 442 YDKVVYDETNHRRWLKGFKKSEKAKYDDKMEEYNNELEELQKEIDMINESMENLK 496
>UniRef50_O30012 Cluster: Chorismate mutase/prephenate dehydratase;
n=1; Archaeoglobus fulgidus|Rep: Chorismate
mutase/prephenate dehydratase - Archaeoglobus fulgidus
Length = 620
Score = 35.5 bits (78), Expect = 3.3
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 39 RVQAQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
R ++E + S+ F ++++ G L L VF G N+ +ESR + T + V+VE
Sbjct: 528 RRSGRSEGKITSLFFGVEDKPGALKDVLEVFHKKGFNLRKLESRPAGTGLGDYVFFVEVE 587
Query: 99 CDPQRMEQLKRMLKREVQDFEVV 121
P R E L LK+ ++VV
Sbjct: 588 A-PLREEDLLD-LKQVTTFYKVV 608
>UniRef50_Q14246 Cluster: EGF-like module-containing mucin-like
hormone receptor-like 1 precursor; n=10; Tetrapoda|Rep:
EGF-like module-containing mucin-like hormone
receptor-like 1 precursor - Homo sapiens (Human)
Length = 886
Score = 35.5 bits (78), Expect = 3.3
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 2/83 (2%)
Query: 300 SDPFYTPEPDCCHELLGHMPLLANPSFAQFSQELGLASLGASDADIDKLATLYFFTVEFG 359
+DP PE C+ +G+ NP F S L L AS DID+ + +
Sbjct: 177 ADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM--CPINST 234
Query: 360 LCRQPDGSFCVYGAGLLSSVAEL 382
P FC G S +L
Sbjct: 235 CTNTPGSYFCTCHPGFAPSNGQL 257
>UniRef50_Q27R78 Cluster: Pol protein; n=3; Human immunodeficiency
virus 1|Rep: Pol protein - Human immunodeficiency virus
1
Length = 97
Score = 35.1 bits (77), Expect = 4.4
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 407 ITSYQNAYYYTDSFEEAKEKMRAFAESIQRPFGVRYNPYTQSVEVLSNAQKITALVSELR 466
+ S N Y +F A K + IQ+ FG+ YNP +Q V V S +++ ++ ++R
Sbjct: 13 MASQSNTYRNGSNFTSAAVKAACWWAGIQQEFGIPYNPQSQGV-VESMNKELKKIIGQVR 71
Query: 467 GDLCIVSSAIK 477
L + K
Sbjct: 72 DKLSTLRQQYK 82
>UniRef50_A4XJH7 Cluster: Prephenate dehydratase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Prephenate dehydratase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 272
Score = 35.1 bits (77), Expect = 4.4
Identities = 15/56 (26%), Positives = 31/56 (55%)
Query: 43 QAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVE 98
+ E + S++F+ ++ G L + L++F +N+ IESR + T + VD++
Sbjct: 182 RGEKNKTSIIFSTYDKPGSLYKILAIFNLYDLNLTKIESRPAKTSLGEYVFFVDID 237
>UniRef50_Q97AD5 Cluster: Prephenate dehydratase; n=1; Thermoplasma
volcanium|Rep: Prephenate dehydratase - Thermoplasma
volcanium
Length = 268
Score = 34.7 bits (76), Expect = 5.8
Identities = 16/41 (39%), Positives = 25/41 (60%)
Query: 42 AQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESR 82
A+ + ++IS+ FTL N+ G L + V GI++ IESR
Sbjct: 177 AKPQGDKISIAFTLLNKPGSLASIVDVLAKYGIDMTKIESR 217
>UniRef50_A0L410 Cluster: Chorismate mutase; n=1; Magnetococcus sp.
MC-1|Rep: Chorismate mutase - Magnetococcus sp. (strain
MC-1)
Length = 368
Score = 34.3 bits (75), Expect = 7.6
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 42 AQAESERISVMFTLKNQVGGLVRALSVFQDLGINVLHIESRKSMTEVSSADILVDVECDP 101
A + +++ S+M + + G L R L VF + GIN+ IESR T+ + D L ++ +
Sbjct: 278 APSGADKTSIMVSFLDDPGFLHRILGVFAERGINLSRIESRP--TQERAWDYLFFIDMEG 335
Query: 102 QRMEQ 106
R ++
Sbjct: 336 HRQDE 340
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 564,351,232
Number of Sequences: 1657284
Number of extensions: 24189838
Number of successful extensions: 59277
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 59062
Number of HSP's gapped (non-prelim): 128
length of query: 502
length of database: 575,637,011
effective HSP length: 104
effective length of query: 398
effective length of database: 403,279,475
effective search space: 160505231050
effective search space used: 160505231050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)
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