BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000641-TA|BGIBMGA000641-PA|IPR006201|Neurotransmitter- gated ion-channel, IPR006028|Gamma-aminobutyric acid A receptor, IPR002289|Gamma-aminobutyric-acid A receptor, beta subunit, IPR013838|Beta tubulin, autoregulation binding site, IPR006202|Neurotransmitter-gated ion-channel ligand-binding, IPR006029|Neurotransmitter-gated ion-channel transmembrane region (269 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 290 3e-77 UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1... 242 6e-63 UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 215 1e-54 UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49... 146 5e-34 UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 142 6e-33 UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 137 2e-31 UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve... 137 3e-31 UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 136 6e-31 UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 134 2e-30 UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 134 3e-30 UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subuni... 133 5e-30 UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea... 132 1e-29 UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 131 2e-29 UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 130 3e-29 UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 129 6e-29 UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 128 1e-28 UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 127 3e-28 UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 126 4e-28 UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subuni... 126 4e-28 UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 125 1e-27 UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella ve... 125 1e-27 UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromado... 124 2e-27 UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subuni... 120 5e-26 UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;... 118 2e-25 UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protei... 118 2e-25 UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 117 4e-25 UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella ve... 116 8e-25 UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 116 8e-25 UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 115 1e-24 UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated... 113 4e-24 UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 113 6e-24 UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 112 1e-23 UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 111 1e-23 UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 110 3e-23 UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 110 4e-23 UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 110 4e-23 UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 109 6e-23 UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 109 6e-23 UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 109 6e-23 UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 109 7e-23 UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; ... 109 1e-22 UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 108 1e-22 UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella ve... 108 2e-22 UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 107 2e-22 UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 107 3e-22 UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 105 9e-22 UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella ve... 105 1e-21 UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella ve... 105 1e-21 UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21 UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 pr... 104 2e-21 UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protei... 103 4e-21 UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; R... 103 4e-21 UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 103 4e-21 UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella ve... 103 6e-21 UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 102 1e-20 UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop l... 101 1e-20 UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; ... 101 1e-20 UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 101 1e-20 UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor... 101 2e-20 UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 99 6e-20 UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 100 8e-20 UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella ve... 100 8e-20 UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 99 1e-19 UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 98 2e-19 UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subun... 98 2e-19 UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; ... 98 2e-19 UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 97 4e-19 UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella ve... 97 4e-19 UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 96 1e-18 UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella ve... 96 1e-18 UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 95 2e-18 UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subun... 95 2e-18 UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 94 3e-18 UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 93 5e-18 UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 93 7e-18 UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 93 7e-18 UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subuni... 93 7e-18 UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory... 93 9e-18 UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 93 9e-18 UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop l... 92 1e-17 UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 92 1e-17 UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 92 1e-17 UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 92 1e-17 UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 92 1e-17 UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric ac... 92 2e-17 UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella ve... 92 2e-17 UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 92 2e-17 UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ... 91 2e-17 UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 91 3e-17 UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 91 3e-17 UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - ... 91 3e-17 UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 91 4e-17 UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 90 6e-17 UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 89 8e-17 UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 89 1e-16 UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;... 88 2e-16 UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 87 4e-16 UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;... 86 1e-15 UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-amin... 85 1e-15 UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor... 85 1e-15 UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopteryg... 85 1e-15 UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 85 2e-15 UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 84 4e-15 UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.... 83 5e-15 UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 83 7e-15 UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 83 1e-14 UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella ve... 83 1e-14 UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome sh... 80 5e-14 UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 80 7e-14 UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 79 9e-14 UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor... 78 3e-13 UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 77 5e-13 UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 77 6e-13 UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; ... 74 4e-12 UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whol... 71 2e-11 UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome sho... 69 1e-10 UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Re... 66 7e-10 UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 66 9e-10 UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 64 4e-09 UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; A... 55 2e-06 UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 54 3e-06 UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05 UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit p... 50 6e-05 UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1... 50 8e-05 UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 46 0.001 UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; ... 42 0.013 UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a pro... 41 0.029 UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 40 0.067 UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 39 0.15 UniRef50_A7I712 Cluster: Putative uncharacterized protein precur... 39 0.15 UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 38 0.20 UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.47 UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 37 0.62 UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 37 0.62 UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 37 0.62 UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 36 0.82 UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 36 0.82 UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 35 1.9 UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 35 2.5 UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 34 3.3 UniRef50_UPI00006CC8B0 Cluster: hypothetical protein TTHERM_0029... 34 4.4 UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 34 4.4 UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8 UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep... 33 5.8 UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty... 33 5.8 UniRef50_Q70Z44 Cluster: 5-hydroxytryptamine receptor 3 family m... 33 7.7 >UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=45; Pancrustacea|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Drosophila melanogaster (Fruit fly) Length = 606 Score = 290 bits (711), Expect = 3e-77 Identities = 139/171 (81%), Positives = 149/171 (87%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 MRDIRY W +G +SVG+SSEV LPQF+VLGHRQRA EI+LTTGNYSRLACEIQFVRSMGY Sbjct: 210 MRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGY 269 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YLIQIYIPSGLIVIISWVSFWLNRNATPARV+LG NAALPKISYVKS Sbjct: 270 YLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKS 329 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQID 171 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF A+QK+A +KK Q+D Sbjct: 330 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380 >UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1b; n=8; Pancrustacea|Rep: Ionotropic GABA receptor beta subunit 1b - Homarus americanus (American lobster) Length = 521 Score = 242 bits (593), Expect = 6e-63 Identities = 116/167 (69%), Positives = 130/167 (77%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 M IR W+ G SV + S+VSLPQF+VLG+ ++ + S +TGNYSRL CEI FVRSMGY Sbjct: 235 MDHIRLSWHAGDRSVVIESDVSLPQFRVLGYNRKTIISSTSTGNYSRLLCEIMFVRSMGY 294 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YLIQIYIPS LIV+ISWVSFWLNR+ATPARVSLG NAALPKISYVKS Sbjct: 295 YLIQIYIPSSLIVVISWVSFWLNRSATPARVSLGVTTVLTMTTLMSSTNAALPKISYVKS 354 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167 IDVYLGTCFVMVFASLLEYA VGYM KRIQMRK R A+QKMA ++K Sbjct: 355 IDVYLGTCFVMVFASLLEYAAVGYMGKRIQMRKNRILAIQKMAEQRK 401 >UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae|Rep: GABA receptor - Tetranychus urticae (Two-spotted spider mite) Length = 585 Score = 215 bits (525), Expect = 1e-54 Identities = 105/167 (62%), Positives = 120/167 (71%), Gaps = 1/167 (0%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 M DI Y W + N+V + S + LPQF + RQ ISLTTGNYSRL CEIQ RSMGY Sbjct: 197 MTDIIYNWVD-ENAVKIDSNLMLPQFSIASIRQSWKYISLTTGNYSRLMCEIQLTRSMGY 255 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 Y+IQIY+P+ LIVIISWVSFWL+RNATPARV LG N+ LPKISYVKS Sbjct: 256 YMIQIYVPASLIVIISWVSFWLHRNATPARVHLGVITVLTMTTLMSSTNSQLPKISYVKS 315 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167 IDV+LGTCFVMVFA+LLEYA VGY+ KRI MRK RF + K A EK+ Sbjct: 316 IDVFLGTCFVMVFAALLEYAAVGYIGKRISMRKNRFQQLAKAAEEKR 362 >UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49B.3; n=11; Eumetazoa|Rep: Ionotropic GABA receptor subunit UNC-49B.3 - Caenorhabditis elegans Length = 506 Score = 146 bits (354), Expect = 5e-34 Identities = 72/158 (45%), Positives = 98/158 (62%), Gaps = 4/158 (2%) Query: 2 RDIRYKWNEGPNSVGVSS----EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57 +DI Y W + + +++ LPQF+ + + ++G Y RLA E+ VR+ Sbjct: 193 KDIDYYWGKKRTDLEITAVKFDTFQLPQFQPTLYFVNTTKAETSSGKYVRLALEVILVRN 252 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 MG+Y + I IPS LIV ISWVSFWLNR A+PARV LG N ++PK+SY Sbjct: 253 MGFYTMNIVIPSILIVTISWVSFWLNREASPARVGLGVTTVLTMTTLITTTNNSMPKVSY 312 Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 VK +DV+L CFVMVFASLLEYA V YM KR+ +R+++ Sbjct: 313 VKGLDVFLNFCFVMVFASLLEYAIVSYMNKRLVLRREK 350 >UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1); n=104; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1) - Homo sapiens (Human) Length = 474 Score = 142 bits (345), Expect = 6e-33 Identities = 72/175 (41%), Positives = 107/175 (61%), Gaps = 6/175 (3%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI + WN G +V +++ LPQF ++ ++ + ++ TTG Y RL+ + R++GY++ Sbjct: 188 DIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFI 247 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG LPKI YVK+ID Sbjct: 248 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307 Query: 123 VYLGTCFVMVFASLLEYATVGYM--AKRIQMR---KQRFTAVQKMAVE-KKIQID 171 +YL CFV VF +LLEYA V Y+ K Q + KQ +A +K +E K+Q+D Sbjct: 308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVD 362 >UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 513 Score = 137 bits (332), Expect = 2e-31 Identities = 70/165 (42%), Positives = 98/165 (59%), Gaps = 5/165 (3%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ W E P GV E LPQF ++G+ + L TG Y RL+ + R++GY++ Sbjct: 202 DVVMSWKETPVR-GVD-EAKLPQFTIIGYETNDRKEKLATGIYQRLSLSFKLQRNIGYFV 259 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 Q Y+PS LIV++SWVSFW+N AT ARV+LG ++LP+ISYVK+ID Sbjct: 260 FQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAID 319 Query: 123 VYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFTAVQKMAV 164 +YL CFV VFA+LLEYA V Y A+ + K++ T +K + Sbjct: 320 IYLVMCFVFVFAALLEYAAVNYTYWGARAKKKSKKKETEEEKKTI 364 >UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 278 Score = 137 bits (331), Expect = 3e-31 Identities = 63/144 (43%), Positives = 93/144 (64%), Gaps = 2/144 (1%) Query: 3 DIRYKWNE--GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 ++ +KWN+ G V VS E+ +PQF + ++ + + TTG+YSRL +F RS+G+ Sbjct: 135 ELIFKWNKNRGNKEVQVSDELQIPQFILTEYKTTSEFANFTTGSYSRLTVLFRFERSIGF 194 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 +LIQ YIP+ LIV++SW++FW+N +TPAR+ LG A+LPK+SYVKS Sbjct: 195 FLIQTYIPAYLIVMLSWIAFWINHTSTPARIGLGITTVLTMTTLTNSARASLPKVSYVKS 254 Query: 121 IDVYLGTCFVMVFASLLEYATVGY 144 I+ +L CF+ VF SL+EY V Y Sbjct: 255 IEWFLIMCFLYVFMSLVEYGCVSY 278 >UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta); n=3; Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit beta precursor (GABA(A) receptor subunit beta) - Caenorhabditis elegans Length = 550 Score = 136 bits (329), Expect = 6e-31 Identities = 65/142 (45%), Positives = 86/142 (60%), Gaps = 1/142 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++ KWN P +V + +PQF + G +S TG+Y RL+ Q RS+GY++ Sbjct: 207 EVLMKWNY-PLAVHGVEQADVPQFTITGFHTEDSIVSTATGSYQRLSLVFQLRRSVGYFI 265 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 Q Y+P LIV++SWVSFW+N AT ARV+LG +LP+ISYVKSID Sbjct: 266 FQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRQSLPRISYVKSID 325 Query: 123 VYLGTCFVMVFASLLEYATVGY 144 +YL CFV VFA+LLEYA V Y Sbjct: 326 IYLVMCFVFVFAALLEYAAVNY 347 >UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens (Human) Length = 512 Score = 134 bits (325), Expect = 2e-30 Identities = 65/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI + W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY++ Sbjct: 187 DIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI 246 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG LPKI YVK+ID Sbjct: 247 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306 Query: 123 VYLGTCFVMVFASLLEYATVGYM-AKRIQMRKQRFTAVQKMAVEKKIQID 171 +YL CFV VF +LLEYA V Y+ R R+++ A +K+++D Sbjct: 307 MYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLD 356 >UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precursor; n=128; Euteleostomi|Rep: Glycine receptor subunit alpha-3 precursor - Homo sapiens (Human) Length = 464 Score = 134 bits (323), Expect = 3e-30 Identities = 68/172 (39%), Positives = 105/172 (61%), Gaps = 8/172 (4%) Query: 1 MRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLACEIQFVRSM 58 M D+ ++W +E P V V+ ++LPQF + + R TG ++ + R M Sbjct: 196 MNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQM 253 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 GYYLIQ+YIPS LIVI+SWVSFW+N +A PARV+LG A+LPK+SYV Sbjct: 254 GYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYV 313 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKR----IQMRKQRFTAVQKMAVEK 166 K+ID+++ C + VF++LLEYA V +++++ ++ R++R + A+EK Sbjct: 314 KAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEK 365 >UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subunit beta-like precursor (GABA(A) receptor); n=11; Protostomia|Rep: Gamma-aminobutyric acid receptor subunit beta-like precursor (GABA(A) receptor) - Drosophila melanogaster (Fruit fly) Length = 496 Score = 133 bits (321), Expect = 5e-30 Identities = 63/142 (44%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ W P V + LPQF ++G+ + L TG Y RL+ + R++GY++ Sbjct: 203 DVVMYWK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFV 260 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 Q Y+PS LIV++SWVSFW+N AT ARV+LG ++LP+ISYVK+ID Sbjct: 261 FQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAID 320 Query: 123 VYLGTCFVMVFASLLEYATVGY 144 +YL CFV VFA+LLEYA V Y Sbjct: 321 IYLVMCFVFVFAALLEYAAVNY 342 >UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis elegans Length = 657 Score = 132 bits (318), Expect = 1e-29 Identities = 64/161 (39%), Positives = 90/161 (55%), Gaps = 1/161 (0%) Query: 2 RDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +DI Y W E P + SLP F++ TG+YS L IQ R Y Sbjct: 409 KDIEYVWKEETPVQLKAGLSSSLPSFQLTNTSTTYCTSKTNTGSYSCLRTIIQLRRQFSY 468 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YL+Q+YIPS ++VI+SWVSFW++R A PARV+LG NA LP ++Y+K+ Sbjct: 469 YLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKA 528 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161 IDV++G C +F +LLE+A V Y+A + K+ T +K Sbjct: 529 IDVWIGACMTFIFCALLEFAWVTYIANKQDANKRARTEREK 569 >UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2 SCAF14781, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 525 Score = 131 bits (317), Expect = 2e-29 Identities = 63/149 (42%), Positives = 94/149 (63%), Gaps = 2/149 (1%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRSMG 59 M D+ ++W E +V VS ++LPQF + ++ TG ++ + + R MG Sbjct: 270 MNDLIFEWLEN-GAVQVSDGLTLPQFIMRDEKELGYCTKHYNTGKFTCIEVKFHLERQMG 328 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 YYLIQ+YIPS LIVI+SWVSFW+N +A PARV+LG A+LPK+SYVK Sbjct: 329 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 388 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKR 148 +ID+++ C + VFA+LLEYA V +++++ Sbjct: 389 AIDIWMAVCLLFVFAALLEYAGVNFVSRQ 417 >UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio rerio|Rep: Glycine receptor, alpha 4b - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 536 Score = 130 bits (315), Expect = 3e-29 Identities = 67/169 (39%), Positives = 102/169 (60%), Gaps = 7/169 (4%) Query: 1 MRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRSM 58 M D+ ++W +EGP V V+ ++ LPQF + + TG ++ + + R M Sbjct: 240 MNDLIFQWLDEGP--VQVADDLMLPQFVLKEEKDLGYCTKHYNTGKFTCIEVKFHLERQM 297 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 GYYLIQ+YIPS L VI+SWVSFW+N +A PARV LG A+LPK+SYV Sbjct: 298 GYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYV 357 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167 K+ID+++ C + VFA+LLEYA V +++++ K+ F +K+ E++ Sbjct: 358 KAIDIWMAVCLLFVFAALLEYAAVNFVSRQY---KEFFRLRRKLRQEQR 403 >UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 319 Score = 129 bits (312), Expect = 6e-29 Identities = 62/145 (42%), Positives = 84/145 (57%), Gaps = 3/145 (2%) Query: 3 DIRYKWNE---GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMG 59 D+ Y WNE +++ + ++ LPQF+VLG + A GN+S L + R +G Sbjct: 175 DVLYVWNERLDNTSAIYIHDDLELPQFEVLGVSRSAKMNKYNIGNHSSLVANFRMKRRIG 234 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 Y+LI YIPS +IVIISW+SFW++ PARV+LG A LPK+SYVK Sbjct: 235 YFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTMTTLISSARANLPKVSYVK 294 Query: 120 SIDVYLGTCFVMVFASLLEYATVGY 144 +ID YL C + VF S+LEY V Y Sbjct: 295 AIDWYLLLCLIFVFGSILEYTCVTY 319 >UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric acid A receptor beta 2S chain precursor - chicken - Strongylocentrotus purpuratus Length = 418 Score = 128 bits (309), Expect = 1e-28 Identities = 57/142 (40%), Positives = 88/142 (61%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ + W G +S+ + + + QF + ++ + +TG+Y RLA + R++G++ Sbjct: 110 DVNFVWQYGDDSLEGVNNIEMAQFTLSDYKLIVKMQNFSTGSYPRLALTFRIKRNVGFFF 169 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q Y+PS L+V++SWVSFW+N AT ARVSLG +LP+ISYVKSID Sbjct: 170 LQTYLPSILLVMLSWVSFWINHEATSARVSLGITTVLTMTTISTAVRQSLPRISYVKSID 229 Query: 123 VYLGTCFVMVFASLLEYATVGY 144 +Y+ TC+ VFA+L+EYA V Y Sbjct: 230 IYVITCYSFVFAALVEYAIVNY 251 >UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-gated chloride channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to glutamate-gated chloride channel - Nasonia vitripennis Length = 510 Score = 127 bits (307), Expect = 3e-28 Identities = 65/160 (40%), Positives = 89/160 (55%), Gaps = 1/160 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ + W EG + V V + LP+F + TG YS L ++ F R YYL Sbjct: 191 DLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYL 249 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQIYIP ++VI+SWVSFWL+++A PARVSLG NA+LP +SY K+ID Sbjct: 250 IQIYIPCCMLVIVSWVSFWLDQSAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAID 309 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162 V+ G C VF +LLE+A V Y ++ R+ Q+M Sbjct: 310 VWTGVCLTFVFGALLEFALVNYASRSDIHRENMKKKYQEM 349 >UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precursor; n=21; Pancrustacea|Rep: Glutamate-gated chloride channel precursor - Drosophila melanogaster (Fruit fly) Length = 456 Score = 126 bits (305), Expect = 4e-28 Identities = 62/145 (42%), Positives = 83/145 (57%), Gaps = 1/145 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ + W EG + V V + LP+F + TG YS L ++ F R YYL Sbjct: 190 DLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYL 248 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQIYIP ++VI+SWVSFWL++ A PARVSLG NA+LP +SY K+ID Sbjct: 249 IQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAID 308 Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147 V+ G C VF +LLE+A V Y ++ Sbjct: 309 VWTGVCLTFVFGALLEFALVNYASR 333 >UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subunit rho-2 precursor (GABA(A) receptor subunit rho-2); n=99; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit rho-2 precursor (GABA(A) receptor subunit rho-2) - Homo sapiens (Human) Length = 465 Score = 126 bits (305), Expect = 4e-28 Identities = 61/154 (39%), Positives = 90/154 (58%), Gaps = 2/154 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 D+ W G S+ ++SL QF + H + +TG Y+RL R + ++ Sbjct: 205 DLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFF 264 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 L+Q Y P+ L+V++SWVSFW++R A PARVSLG NA++P++SYVK++ Sbjct: 265 LLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAV 324 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 D+YL FV VF S+LEYA V Y+ +Q RK+R Sbjct: 325 DIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKER 357 >UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride-ion channel/receptor, zeta subunit precursor; n=1; Lymnaea stagnalis|Rep: Gamma-aminobutyric acid-grated chloride-ion channel/receptor, zeta subunit precursor - Lymnaea stagnalis (Great pond snail) Length = 437 Score = 125 bits (301), Expect = 1e-27 Identities = 60/142 (42%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Query: 9 NEGPNSVGVSSEVSLPQFKVLGHRQRAME--ISLTTGNYSRLACEIQFVRSMGYYLIQIY 66 N ++ V SEV LPQF+V GN+S + E R++G+Y++Q+Y Sbjct: 210 NPDGKAIVVDSEVLLPQFEVKSVIPSFCNRRYHQKAGNHSCIQAEFHLARNIGFYIVQMY 269 Query: 67 IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126 IPS LIV++SW+SFWL N+ P RVSLG NAALP++SY K+IDV++ Sbjct: 270 IPSMLIVMLSWISFWLTVNSVPGRVSLGLLTVLTMTTQSSSVNAALPRVSYTKAIDVWMS 329 Query: 127 TCFVMVFASLLEYATVGYMAKR 148 TC V VFA+LLE+A V ++++ Sbjct: 330 TCLVFVFAALLEFAVVNVLSRK 351 >UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 469 Score = 125 bits (301), Expect = 1e-27 Identities = 65/167 (38%), Positives = 96/167 (57%), Gaps = 3/167 (1%) Query: 4 IRYKWN--EGPNSVGVSSEVSL-PQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 I YKW EG V +V L PQF + + GN+S + F R+ + Sbjct: 202 IMYKWEKGEGDGMSFVPRDVKLLPQFNLTKLELSSRNTQYVIGNWSGVMATFTFERTYSF 261 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 Y+I IY PS LIV+ISW+SF L R+ +PARV+LG N A+PK++YVK+ Sbjct: 262 YVIHIYGPSALIVLISWISFLLPRDQSPARVTLGVTSVLTEVTILTMSNNAMPKVNYVKA 321 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167 +D YL CF+ VFASL+EY+ + +A R R+++ A +++A+EK+ Sbjct: 322 VDKYLIACFLFVFASLMEYSLILVLANRTMRREKQKRAAKRLAMEKE 368 >UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromadorea|Rep: GBR-2A protein precursor - Haemonchus contortus (Barber pole worm) Length = 421 Score = 124 bits (300), Expect = 2e-27 Identities = 60/155 (38%), Positives = 88/155 (56%), Gaps = 1/155 (0%) Query: 2 RDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +DI+Y+W E P SLP F++ + TG YS L ++ R Y Sbjct: 204 QDIKYEWKEQNPVQQKDGLRQSLPSFELQDVVTKYCTSKTNTGEYSCLRTQMVLRREFSY 263 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YL+Q+YIPS ++VI+SWVSFWL++++ PARV+LG NA +P +SY K+ Sbjct: 264 YLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINANVPPVSYTKA 323 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 IDV++G C +F +LLE+A V Y A++ QR Sbjct: 324 IDVWIGVCLAFIFGALLEFAWVNYAARKDMSCGQR 358 >UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subunit beta precursor; n=8; Chromadorea|Rep: Glutamate-gated chloride channel subunit beta precursor - Caenorhabditis elegans Length = 434 Score = 120 bits (288), Expect = 5e-26 Identities = 64/163 (39%), Positives = 88/163 (53%), Gaps = 2/163 (1%) Query: 1 MRDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLT-TGNYSRLACEIQFVRSM 58 M DI Y+W+ P + LP F + + A S T TG+Y L ++ F R Sbjct: 186 MNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCTSHTNTGSYGCLRMQLLFKRQF 245 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 YYL+Q+Y P+ +IVI+SWVSFW++ ++T RV+LG NA LP +SYV Sbjct: 246 SYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYV 305 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161 K +DV+LG C VF +LLEYA V Y Q + R A +K Sbjct: 306 KVVDVWLGACQTFVFGALLEYAFVSYQDSVRQNDRSREKAARK 348 >UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 447 Score = 118 bits (284), Expect = 2e-25 Identities = 55/148 (37%), Positives = 85/148 (57%), Gaps = 2/148 (1%) Query: 3 DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 ++ YKW +GP SV V+ E S L Q+ ++GH +IS + G Y+ + R +GY Sbjct: 194 EVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTEDISTSRGQYTVMMAHFYLKRKIGY 253 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 ++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++Y + Sbjct: 254 FVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 313 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148 +D ++ C+ VF++L+E+ATV Y KR Sbjct: 314 MDWFIAVCYAFVFSALIEFATVNYFTKR 341 >UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protein 4; n=2; Caenorhabditis|Rep: Glutamate-gated chloride channel protein 4 - Caenorhabditis elegans Length = 500 Score = 118 bits (283), Expect = 2e-25 Identities = 55/169 (32%), Positives = 90/169 (53%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI Y W+ + + +LP F++ + + TG YS L EI+ R ++L Sbjct: 209 DIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSKTNTGTYSCLKVEIRLNRVFSFFL 268 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q+YIPS ++V ++WVS+W++ +T ARV L N+ LP +SY KSID Sbjct: 269 LQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTSHAINSNLPPVSYAKSID 328 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQID 171 +++G C V +F SL+EYA V Y+ + R+ + A + + I+ D Sbjct: 329 IWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKKAACNRSRLSNVIEND 377 >UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopterygota|Rep: CG14723-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 426 Score = 117 bits (281), Expect = 4e-25 Identities = 56/142 (39%), Positives = 82/142 (57%), Gaps = 1/142 (0%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 + D+ + WN V V++E+ LPQ + + I +TGN++ LA R +GY Sbjct: 207 VEDLVFIWNMTDPLV-VNTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGY 265 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 +L YIPS LIV++SW+SFW+ A PARV+LG +LP +SYVK+ Sbjct: 266 HLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKA 325 Query: 121 IDVYLGTCFVMVFASLLEYATV 142 IDV++ +C V VF SL+E+A V Sbjct: 326 IDVWMSSCSVFVFLSLMEFAVV 347 >UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 373 Score = 116 bits (278), Expect = 8e-25 Identities = 57/147 (38%), Positives = 88/147 (59%), Gaps = 4/147 (2%) Query: 1 MRDIRYKWNEGPNS--VGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRS 57 + D+ YKW G + + V +++L +F L Q +IS TG++S + E R Sbjct: 110 INDVVYKWRLGRSDEDIKVKQDLALTKF-TLWKIQTFTKISHYVTGSFSGIVAEFTMTRR 168 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 YY+IQI++P +IV +SW+SFW++ ++TPAR++LG ++LPK+ Y Sbjct: 169 ALYYVIQIFLPCAMIVFLSWISFWIDSHSTPARIALGITTVLSMTTLLFGVQSSLPKVPY 228 Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGY 144 VKS+DVY+ F +VFASL+EYA V Y Sbjct: 229 VKSLDVYMFVSFTLVFASLIEYACVHY 255 >UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta); n=18; Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit theta precursor (GABA(A) receptor subunit theta) - Homo sapiens (Human) Length = 632 Score = 116 bits (278), Expect = 8e-25 Identities = 52/145 (35%), Positives = 82/145 (56%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 + DI W++ N++ ++ E+ +PQF LG + E+ TG+Y RL + Q R + Sbjct: 208 VEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNS 267 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YL+Q+Y P+ L I SW+SFW+N +++ ARV++G LP IS +K+ Sbjct: 268 YLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKA 327 Query: 121 IDVYLGTCFVMVFASLLEYATVGYM 145 ID+Y+ C VF SLLEY + Y+ Sbjct: 328 IDIYILVCLFFVFLSLLEYVYINYL 352 >UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3); n=106; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit gamma-3 precursor (GABA(A) receptor subunit gamma-3) - Homo sapiens (Human) Length = 467 Score = 115 bits (277), Expect = 1e-24 Identities = 54/141 (38%), Positives = 84/141 (59%), Gaps = 4/141 (2%) Query: 6 YKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 Y+W + NSV + + S L QF +G R ++ + G+Y + + R MGY+ I Sbjct: 201 YRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTI 258 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 Q YIP L V++SWVSFW+ ++ATPAR +LG +LP++SYV ++D+ Sbjct: 259 QTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDL 318 Query: 124 YLGTCFVMVFASLLEYATVGY 144 ++ CF+ VFA+L+EYAT+ Y Sbjct: 319 FVTVCFLFVFAALMEYATLNY 339 >UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated chloride channel; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to GABA-gated chloride channel - Strongylocentrotus purpuratus Length = 530 Score = 113 bits (272), Expect = 4e-24 Identities = 53/125 (42%), Positives = 77/125 (61%), Gaps = 3/125 (2%) Query: 3 DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 D+++KW E GP V V ++SLPQFK L R+ GNY+ ++ + R + YY Sbjct: 199 DVKFKWLENGP--VYVDPKISLPQFKFLDSSVRSRIAEYFVGNYTVVSADFYLGRDITYY 256 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 ++Q YIPS +I +SW+SFW+NRNA PARV+LG +LPK+SY+K+I Sbjct: 257 VVQTYIPSSMITCLSWLSFWINRNAVPARVALGITTVLTMTTLVGNAGNSLPKLSYIKAI 316 Query: 122 DVYLG 126 D++LG Sbjct: 317 DLFLG 321 >UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome undetermined SCAF14659, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 481 Score = 113 bits (271), Expect = 6e-24 Identities = 58/168 (34%), Positives = 94/168 (55%), Gaps = 2/168 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNYSRLACEIQFVRSMGYY 61 DI Y W+E V ++ L QF + +R M + G + RL+ Q R+ G Y Sbjct: 212 DIVYHWSESQQHVHGLDKLELSQFTITDYRFDTEMMNFKSAGRFPRLSLCFQLRRNRGVY 271 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 +IQ Y+PS L+V +SWVSFW++++A PARV+LG ++LP+ S +K++ Sbjct: 272 IIQSYMPSILLVAMSWVSFWISQSAVPARVTLGITTVLTMTTLMVSARSSLPRASAIKAL 331 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQ 169 DVY C+V VFA+L+EYA Y A +++++ K++ E ++ Sbjct: 332 DVYFWICYVFVFAALIEYAFAHYNAD-YRLKEKAKVKASKLSSESIVK 378 >UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 538 Score = 112 bits (269), Expect = 1e-23 Identities = 52/149 (34%), Positives = 82/149 (55%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 +R W V +V LP F + G + +L ++ F RS G+Y++ Sbjct: 243 VRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRRSYGFYIL 302 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 QIY+P+ +V+ISW+SFWL+R + PARV+LG + +LPK+SYVK +D+ Sbjct: 303 QIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYVKGLDL 362 Query: 124 YLGTCFVMVFASLLEYATVGYMAKRIQMR 152 ++ C V +F S++E A VG + +R Q R Sbjct: 363 FMFGCIVYIFLSIVELAVVGSLEQRKQQR 391 >UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Aplysia californica|Rep: GABA A receptor alpha subunit - Aplysia californica (California sea hare) Length = 448 Score = 111 bits (268), Expect = 1e-23 Identities = 52/146 (35%), Positives = 81/146 (55%), Gaps = 1/146 (0%) Query: 3 DIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 D+ YKW G S+ ++ ++ L QF ++G+ + +S L Q R GY+ Sbjct: 185 DVIYKWRYGLQGSIELAPDLRLSQFDLVGYPLTNYTGLVKGAVHSVLCVTFQLSRHTGYF 244 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 LI +Y+P L+V++SW SFW+NR AT R++LG + LPK+SY+ ++ Sbjct: 245 LINLYLPCCLLVVLSWASFWINREATADRIALGSTTVLTMTILGIENKSQLPKVSYITAL 304 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAK 147 DVY+ CFV V A+ +E+A V Y K Sbjct: 305 DVYVALCFVFVIATTIEFAVVHYFTK 330 >UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi); n=19; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit pi precursor (GABA(A) receptor subunit pi) - Homo sapiens (Human) Length = 440 Score = 110 bits (265), Expect = 3e-23 Identities = 51/156 (32%), Positives = 84/156 (53%), Gaps = 1/156 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ + W G +SV + L Q+ + + TGNY+RL + + R++ Y++ Sbjct: 187 DVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRRNVLYFI 246 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS-YVKSI 121 ++ Y+PS +V++SWVSFW++ ++ PAR +G +LP + ++K+I Sbjct: 247 LETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAI 306 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFT 157 DVYLG CF VF +LLEYA Y + + K R T Sbjct: 307 DVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGT 342 >UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 304 Score = 110 bits (264), Expect = 4e-23 Identities = 56/142 (39%), Positives = 76/142 (53%), Gaps = 2/142 (1%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +R + Y+W P + E+S QF + G YS L F R +G+ Sbjct: 151 VRHLLYRWKNSPGIKVLDGEMS--QFYMTRITTSLRNEIYVAGEYSVLKASFTFQRRVGF 208 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 YLIQIYIP IV ++W+S W++R ATPARVSL NA++P++SYVKS Sbjct: 209 YLIQIYIPCMAIVFVAWMSLWVDRRATPARVSLCITTLLTIATIWGNVNASMPRVSYVKS 268 Query: 121 IDVYLGTCFVMVFASLLEYATV 142 ID+YL T F V +LLEY + Sbjct: 269 IDIYLMTSFTFVLGTLLEYIVI 290 >UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta); n=27; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit delta precursor (GABA(A) receptor subunit delta) - Homo sapiens (Human) Length = 452 Score = 110 bits (264), Expect = 4e-23 Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 1/154 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNYSRLACEIQFVRSMGYY 61 DI Y W+E + ++ L QF + +R ++ + G + RL+ R+ G Y Sbjct: 191 DIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFHLRRNRGVY 250 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 +IQ Y+PS L+V +SWVSFW+++ A PARVSLG ++LP+ S +K++ Sbjct: 251 IIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKAL 310 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 DVY C+V VFA+L+EYA + A + +K + Sbjct: 311 DVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK 344 >UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 291 Score = 109 bits (263), Expect = 6e-23 Identities = 48/139 (34%), Positives = 80/139 (57%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 +D+ Y+W + P ++ SS++ + + ++ + TG Y+ L + F R + +Y Sbjct: 153 KDLVYEWMKNPPALEFSSQLRMAHYDLIEWSTESKLDEFVTGKYASLTAKFVFKRRVRFY 212 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 ++ +IP+ IVI+SWV FW++ + PARVSLG + LP++ Y+K+I Sbjct: 213 ILSAFIPAAFIVILSWVGFWIDERSVPARVSLGITTVLAITTLIFGVQSTLPRVGYIKAI 272 Query: 122 DVYLGTCFVMVFASLLEYA 140 DVYL F+ VFASL+EYA Sbjct: 273 DVYLLGNFLFVFASLVEYA 291 >UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4); n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-4 precursor (GABA(A) receptor subunit alpha-4) - Homo sapiens (Human) Length = 554 Score = 109 bits (263), Expect = 6e-23 Identities = 56/152 (36%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Query: 6 YKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 Y W +GP SV V E S L Q+ ++G + I TG Y + R MGY++I Sbjct: 202 YTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMI 261 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 Q YIP + VI+S VSFW+N+ + PAR G +LPK+SY+ ++D Sbjct: 262 QTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYLTAMDW 321 Query: 124 YLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 ++ CF VF++L+E+A V Y IQM K + Sbjct: 322 FIAVCFAFVFSALIEFAAVNYFT-NIQMEKAK 352 >UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3); n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3) - Homo sapiens (Human) Length = 492 Score = 109 bits (263), Expect = 6e-23 Identities = 54/148 (36%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Query: 3 DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 ++ Y W G N SV V+ + S L Q+ +LGH I +TG Y + R +GY Sbjct: 218 EVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGY 277 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 ++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++Y + Sbjct: 278 FVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 337 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148 +D ++ C+ VF++L+E+ATV Y KR Sbjct: 338 MDWFIAVCYAFVFSALIEFATVNYFTKR 365 >UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5); n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor subunit alpha-5 precursor (GABA(A) receptor subunit alpha-5) - Homo sapiens (Human) Length = 462 Score = 109 bits (262), Expect = 7e-23 Identities = 52/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Query: 3 DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 ++ Y W G SV V+ + S L Q+ ++G IS +TG Y+ + R +GY Sbjct: 200 EVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGY 259 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 ++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++Y + Sbjct: 260 FVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 319 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148 +D ++ C+ VF++L+E+ATV Y KR Sbjct: 320 MDWFIAVCYAFVFSALIEFATVNYFTKR 347 >UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 564 Score = 109 bits (261), Expect = 1e-22 Identities = 60/156 (38%), Positives = 89/156 (57%), Gaps = 11/156 (7%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVL--------GHRQRAM-EISLTTGNYSRLACEI 52 + + W + N V + E+ LP+F++ G Q A+ E S + ++S L+ + Sbjct: 177 KQVNVTWFD-KNPVRFNEEIGLPEFQIEHVSNAYCNGSYQYALTENSYKSDDFSCLSGNL 235 Query: 53 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAAL 112 RS+GY L+Q YIP+GLIV+ISWVSFW++R A PARV+L L Sbjct: 236 FLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVPARVTLSFTTLVSLTTLGNGLRFGL 295 Query: 113 PKISYVKSIDVYLGTCFVMVFASLLEYATV-GYMAK 147 P++SY K+ID++ G C VF +LLE+AT+ YM K Sbjct: 296 PQVSYAKAIDLWYGACMFFVFCALLEFATINSYMRK 331 >UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA-gated ion channel - Nasonia vitripennis Length = 442 Score = 108 bits (260), Expect = 1e-22 Identities = 53/146 (36%), Positives = 78/146 (53%), Gaps = 1/146 (0%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 RD+ YKWN V ++ ++ L QF ++G+ S + YS L R MG + Sbjct: 200 RDVIYKWNSA-RQVAIAHDMKLSQFDLVGNPTANATDSTLSQKYSMLLVSFHLKRHMGNF 258 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 LIQ+Y P L+V++SWVSFWLNR AT RVSLG LPK+ Y ++ Sbjct: 259 LIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPTAL 318 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAK 147 D ++ F +FA+++++A V Y K Sbjct: 319 DFFVFLSFGFIFATIIQFAVVHYFTK 344 >UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 293 Score = 108 bits (259), Expect = 2e-22 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 3/143 (2%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNYSRLACEIQFVRSMG 59 + DI Y+W + + + E++ +F++ R +R + TG Y+ L + F R + Sbjct: 153 INDIDYRWKAKEDLIILDGEMN--EFELKDSRGERKQKSRSCTGTYTHLVAKFVFRRRLA 210 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 Y IQIY P+ LIV++SW+SFW++++A PARV+LG ++PK+SY+K Sbjct: 211 YSFIQIYSPTFLIVVLSWLSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIK 270 Query: 120 SIDVYLGTCFVMVFASLLEYATV 142 +ID+YL F+ VF +LLEY V Sbjct: 271 AIDLYLIVSFIFVFGTLLEYIAV 293 >UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 424 Score = 107 bits (258), Expect = 2e-22 Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 2/145 (1%) Query: 3 DIRYKW-NEGPNSVGVSSEV-SLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +++Y+W N N + V+ ++ +PQ+ + GN+S L +F R GY Sbjct: 156 NVQYQWENRSDNGIAVNKKIRDMPQYNLSDINVSRHFTMYVAGNWSGLTATFRFRRRSGY 215 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 ++I IY P LIVI+SW+SF + +T AR++LG N ++PK+SYVK+ Sbjct: 216 FIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKA 275 Query: 121 IDVYLGTCFVMVFASLLEYATVGYM 145 +D YL CF+ VFA LLEY V Y+ Sbjct: 276 VDWYLIGCFLFVFAVLLEYTFVLYI 300 >UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep: PREDICTED: gamma-aminobutyric acid A receptor, alpha 6 isoform 1 - Pan troglodytes Length = 478 Score = 107 bits (257), Expect = 3e-22 Identities = 55/155 (35%), Positives = 82/155 (52%), Gaps = 3/155 (1%) Query: 3 DIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +I Y W +GP SV V E S L Q+ ++G + I TG Y + R MGY Sbjct: 208 EIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGY 267 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 ++IQIY P + VI+S VSFW+N+ + PAR G +LPK+SY + Sbjct: 268 FMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATA 327 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 +D ++ CF VF++L+E+A V Y +Q +K + Sbjct: 328 MDWFIAVCFAFVFSALIEFAAVNYFT-NLQTQKAK 361 >UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis mellifera|Rep: GABA-gated ion channel - Apis mellifera (Honeybee) Length = 463 Score = 105 bits (253), Expect = 9e-22 Identities = 53/148 (35%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFVRSMG 59 RD+ YKWN V ++ ++ L QF ++ + S T + YS L R MG Sbjct: 156 RDVIYKWNSA-RQVAIAEDMKLSQFDLVANPTANYSASTTLSHAEYSMLLVYFHLQRHMG 214 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 +LIQ+Y P L+V++SWVSFWLNR AT RVSLG LPK+ Y Sbjct: 215 NFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPT 274 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAK 147 ++D ++ F +FA+++++A V Y K Sbjct: 275 ALDFFVFLSFAFIFATIIQFAVVHYFTK 302 >UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 291 Score = 105 bits (252), Expect = 1e-21 Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Query: 7 KWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65 KW G SV + ++LPQ VLG + R + +GNYSRL+ +F R + +L + Sbjct: 152 KWKFGETGSVTWAENINLPQMDVLGVKGREVVDVFASGNYSRLSLAFKFKRRISLFLTET 211 Query: 66 YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125 Y+P LIV +SWVSFW+N PARV+L +LPK++Y K D L Sbjct: 212 YVPLVLIVALSWVSFWINYKVAPARVALCITTVLTIITLSASVRTSLPKVTYTKYSDWIL 271 Query: 126 GTCFVMVFASLLEYATVGY 144 T V VF +L+EYA V Y Sbjct: 272 ITGLVYVFGALVEYAVVNY 290 >UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 366 Score = 105 bits (252), Expect = 1e-21 Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 3/144 (2%) Query: 1 MRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAM-EISLTTGNYSRLACEIQFVRSM 58 + D+ Y WN G + + + + QF + + M SL TG++ L +F R Sbjct: 108 VEDVIYNWNNRGTTPIEIFAG-EMAQFDMTEMTMQTMITFSLLTGSFDSLRVSFRFKRRT 166 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 Y+++Q Y+PS IV +SW+ FW+N+NA PAR+SL N++LP+ISY+ Sbjct: 167 SYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYL 226 Query: 119 KSIDVYLGTCFVMVFASLLEYATV 142 K++D YL F+ + AS++EY V Sbjct: 227 KAVDYYLIISFMFILASMVEYVLV 250 >UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 434 Score = 104 bits (250), Expect = 2e-21 Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 3/158 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ +W E V ++ +LP F++ ++ + T G + RL+ I F R G+Y+ Sbjct: 208 DVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTEAYTAGMWHRLSVSIHFERLYGFYI 267 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q+Y+P+ + V ISW++FW++ A PAR++L +LPK SYVK+ID Sbjct: 268 LQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMALTFQFGNIVKSLPKASYVKAID 327 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQ 160 +++ +C +F SL+E A V Y K M QR V+ Sbjct: 328 IWMFSCVGFIFFSLIELAIVAYNDK---MHDQRLREVR 362 >UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 precursor; n=2; Caenorhabditis|Rep: Glycine receptor subunit beta-type 4 precursor - Caenorhabditis elegans Length = 473 Score = 104 bits (250), Expect = 2e-21 Identities = 52/142 (36%), Positives = 75/142 (52%), Gaps = 1/142 (0%) Query: 7 KWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIY 66 +WN G N V V+ + +P + + TG +S E R + +++IQ Y Sbjct: 197 RWNGG-NPVEVNRGIRMPDMHLKHIKFYTKRDKYATGIWSSAVAEFHVDREITHHIIQSY 255 Query: 67 IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126 IP+ LIVIISW SFWL+ A P RVSL ALP+ S VK+IDV++G Sbjct: 256 IPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARMALPQASDVKAIDVWMG 315 Query: 127 TCFVMVFASLLEYATVGYMAKR 148 TC VF++++E+ V Y +R Sbjct: 316 TCMAFVFSAMIEFTVVNYCVRR 337 >UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protein 1; n=6; Caenorhabditis|Rep: Expulsion defective (Defecation) protein 1 - Caenorhabditis elegans Length = 539 Score = 103 bits (248), Expect = 4e-21 Identities = 52/158 (32%), Positives = 83/158 (52%), Gaps = 3/158 (1%) Query: 6 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65 YKW++G + ++ LP F + + S TGNYSRL F RS G+ +Q+ Sbjct: 261 YKWSKGARTALELKKIRLPDFTIQEAYVTSQMESYATGNYSRLYVCFVFSRSSGFCFLQL 320 Query: 66 YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125 IPS +VI SWVS W+ T N +P++SY+K++D+YL Sbjct: 321 IIPSTAVVITSWVSLWME---TETEFQDMISIILAITFLIFSYNEMMPRVSYIKAMDIYL 377 Query: 126 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMA 163 G CF++VF SL++ A V YM ++I + ++++M+ Sbjct: 378 GVCFMIVFLSLIKLALVKYMRQKIMLTSDSGNSLREMS 415 >UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; Rhabditida|Rep: GABA A/glycine receptor subunit - Haemonchus contortus (Barber pole worm) Length = 472 Score = 103 bits (248), Expect = 4e-21 Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 6/155 (3%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS--LTTG-NYSRLACEIQFVRSMG 59 D+ Y W + + + +S Q+K+LG + S G N S L + R G Sbjct: 191 DVVYYWKDVELDAKMGNMLS--QYKILGLFKSEHNFSDHREIGRNISVLKVYFKLQRQQG 248 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 YY++QIY P L+V++SWVSFW+N+ A+PARV+LG LPK+S+ Sbjct: 249 YYVLQIYTPCTLLVVMSWVSFWINKEASPARVALGIMTVLSMSTLGFGLRTDLPKVSHST 308 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154 ++D+Y+ +CF VFA+++EY+ + Y A+ + +RKQ Sbjct: 309 ALDIYILSCFGFVFAAMVEYSVINY-AQIVYIRKQ 342 >UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 103 bits (248), Expect = 4e-21 Identities = 48/148 (32%), Positives = 79/148 (53%), Gaps = 2/148 (1%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLP--QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58 M+D+ YKW + P + + L +F ++ + GN+S L I R Sbjct: 155 MKDVVYKWLDDPKQKTIETAEGLDATEFSIVSLKTMENISVFNLGNFSSLTMRIYLDRRT 214 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 YY+IQIYIP +IV++SW+SFWL+ + PAR +LG ++LP + Y+ Sbjct: 215 TYYVIQIYIPCSMIVMLSWISFWLDYKSVPARTALGITTVLAMTTLLFGIQSSLPGVPYI 274 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMA 146 K++D +L F VF +L+E+A V +++ Sbjct: 275 KAVDQFLIVSFACVFVALIEFAVVNFIS 302 >UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 201 Score = 103 bits (246), Expect = 6e-21 Identities = 49/115 (42%), Positives = 67/115 (58%) Query: 42 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXX 101 TGN+S L +F R + YYL + YIP+ L V++SWVSFW++ ATPAR+SL Sbjct: 4 TGNFSALTVGFRFRREVYYYLFRFYIPASLTVVMSWVSFWISPLATPARISLTIITVLAM 63 Query: 102 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF 156 + PK SY +S DVY+ CFV VF L+EYA V Y+ + + K+ F Sbjct: 64 AGFLIGDHPDFPKSSYARSFDVYMMMCFVFVFGCLVEYAAVHYLLRDDKYNKKVF 118 >UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 262 Score = 102 bits (244), Expect = 1e-20 Identities = 53/155 (34%), Positives = 85/155 (54%), Gaps = 8/155 (5%) Query: 3 DIRYKWNEGP-----NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57 D+ W P N+V +S +++ QF + + + TG ++ L R Sbjct: 106 DLLLSWKADPGDKYKNAVIISDNLTMSQFALDEYHASKETFTYPTGTFTLLKLTFSIRRK 165 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 YY++Q YIP+ LIVI+SWVSFW+ R++ PARV+LG +++P++SY Sbjct: 166 KFYYVVQTYIPTILIVILSWVSFWIPRSSPPARVALGITTVLALTTLIFGIQSSMPRVSY 225 Query: 118 VKSIDVYLGTCFVMVFASLLEYAT---VGYMAKRI 149 VK+ID +L F+ VF +L+EY + + + AKRI Sbjct: 226 VKAIDWFLMVSFLFVFCALIEYPSSTFIKFQAKRI 260 >UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop ligand-gated ion channel subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cys-loop ligand-gated ion channel subunit - Nasonia vitripennis Length = 513 Score = 101 bits (243), Expect = 1e-20 Identities = 49/157 (31%), Positives = 91/157 (57%), Gaps = 11/157 (7%) Query: 1 MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLACE 51 ++D+ W+E P + ++ E+ L +++++ E+S TT GN+S ++ Sbjct: 203 VQDMILNWDEAP--IVLADELHLTEYRLVEQWVNRSEVSYTTAQQHYGHFAGNFSSISIT 260 Query: 52 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAA 111 + R MG++++ YIPS LIV+ISWVSFWL+ +A+P R+ LG + Sbjct: 261 FKLAREMGFFMMDYYIPSILIVVISWVSFWLHVDASPPRIVLGTNTILAFMTLASKVENS 320 Query: 112 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 LPK+SY+K+ +++ C + +FA+++E+A V + +R Sbjct: 321 LPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTIYRR 357 >UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 382 Score = 101 bits (243), Expect = 1e-20 Identities = 51/133 (38%), Positives = 70/133 (52%) Query: 39 SLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXX 98 S G +S L ++ R++G++L+Q YIP+GLIV ISWVSFW++R A PARVSL Sbjct: 182 SSRVGEFSCLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDRRAVPARVSLSFTTL 241 Query: 99 XXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTA 158 ALP +SY K+ID + G C + +F LLE+A V +R Sbjct: 242 LTLSTQGNGIRYALPAVSYAKAIDYFYGVCMLFIFGVLLEFAAVNSYMRRANKYNHMAEK 301 Query: 159 VQKMAVEKKIQID 171 +Q K I D Sbjct: 302 IQSAYGGKPIIAD 314 >UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acc-1 - Caenorhabditis elegans Length = 466 Score = 101 bits (243), Expect = 1e-20 Identities = 51/145 (35%), Positives = 81/145 (55%), Gaps = 1/145 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++R +WN+ P V + + LP FK++ A+E G + L F R G+Y+ Sbjct: 185 EVRMQWNQ-PYPVILLKRIELPDFKLVNFSVIAVEQMYPAGWWDELTVAFVFERRYGWYV 243 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q YIP+ + ++ISW+SF+L A PAR LG LP++SYVK+ID Sbjct: 244 LQGYIPTMVTIVISWISFYLGPRAIPARTMLGVNSLLAMTFQFGNIIRNLPRVSYVKAID 303 Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147 V++ + + +F SLLE A VG+M++ Sbjct: 304 VWMLSGMLFIFLSLLELAVVGFMSR 328 >UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor; n=34; Euteleostomi|Rep: Glycine receptor subunit beta precursor - Homo sapiens (Human) Length = 497 Score = 101 bits (242), Expect = 2e-20 Identities = 57/165 (34%), Positives = 90/165 (54%), Gaps = 8/165 (4%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLACEIQFVRSMG 59 D+R+ W G + V + +++LPQF + + TG Y+ + R +G Sbjct: 210 DLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVG 267 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 +Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A LPK+SYVK Sbjct: 268 FYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVK 327 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFTAVQK 161 ++DV+L C + FASL+EYA V M KR++ K R ++ Sbjct: 328 ALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQ 372 >UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 99 bits (238), Expect = 6e-20 Identities = 43/136 (31%), Positives = 75/136 (55%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 +I +W EG V +S +++LP F ++G + + +G ++ L I F R +GYYL Sbjct: 135 EIVLRWEEGDTPVAISKDMNLPHFDIVGLETKQIYNVYKSGKFNSLEVHITFRRRLGYYL 194 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQ Y+P + +SW+ FW++ + T R+++G N +PK+SY+K+ID Sbjct: 195 IQTYLPCVFLCFLSWMPFWMDPSETGDRLAVGITAVLTIVFLAGAMNTNMPKVSYMKAID 254 Query: 123 VYLGTCFVMVFASLLE 138 Y+ CF+ + S +E Sbjct: 255 WYVIACFLTMVLSFVE 270 >UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7411-PA - Drosophila melanogaster (Fruit fly) Length = 485 Score = 99.5 bits (237), Expect = 8e-20 Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ ++W+ V V + LPQ ++ + +TGN++ L R + YY+ Sbjct: 182 DLIFQWDPTTPLV-VDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYV 240 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 YIP+ +IVI+SWVSFW+ A PARV+LG ++LP +SY+K++D Sbjct: 241 FNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVD 300 Query: 123 VYLGTCFVMVFASLLEYATV 142 ++ C V VF +L+EY + Sbjct: 301 AFMSVCTVFVFMALMEYCLI 320 >UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 99.5 bits (237), Expect = 8e-20 Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 5/142 (3%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 D+ Y WN+ G +L QF +LG + T+G YS L +F R + YL Sbjct: 116 DLYYDWNDVSIYKG-----NLSQFDLLGLDSLRKSLVFTSGTYSSLVATFRFRRRIQNYL 170 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 + Y+P+ L V++SWVSF+++ N+ PAR +LG + P +SYV S D Sbjct: 171 LSFYVPTILTVMLSWVSFFISPNSAPARCALGIITVLAVGGFLTNQRKSFPTVSYVMSAD 230 Query: 123 VYLGTCFVMVFASLLEYATVGY 144 +Y+ C+V VF +LLEYA V + Sbjct: 231 LYILVCYVFVFCALLEYAVVHF 252 >UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 469 Score = 99.1 bits (236), Expect = 1e-19 Identities = 50/147 (34%), Positives = 80/147 (54%), Gaps = 1/147 (0%) Query: 13 NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI-YIPSGL 71 N V V E+SL F + +R G + RL E +F R G+Y++Q+ Y+P+ + Sbjct: 190 NPVTVLPEISLADFDLSRYRTSRHTEVYKAGEWYRLTVEFEFTRKYGFYILQVLYVPTYI 249 Query: 72 IVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVM 131 + ISW++F ++ A PAR+ LG +LP +SYVK+ID+++ TC Sbjct: 250 SLFISWIAFCIDTKALPARIVLGVNSLMSLTFQFGNIIRSLPPVSYVKAIDLWMCTCVGF 309 Query: 132 VFASLLEYATVGYMAKRIQMRKQRFTA 158 +FASLLE A V Y K++ ++ + A Sbjct: 310 IFASLLELAFVAYQDKKLILKSGKSNA 336 >UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 457 Score = 98.3 bits (234), Expect = 2e-19 Identities = 50/155 (32%), Positives = 80/155 (51%), Gaps = 1/155 (0%) Query: 2 RDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +++R +WNE V V++++ LP F+++ + G + L ++ F R + Sbjct: 207 QEVRMRWNEKSAEPVSVTNKIRLPDFELIKIESTRISAPYPAGMWDELHVKLVFERRYIW 266 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 Y +Q Y+P+ L + ISW+SF L A PAR LG LP++SYVK+ Sbjct: 267 YFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNALLAMIFQFGNIMRNLPRVSYVKA 326 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 IDV++ +F SLLE A VGY K + K++ Sbjct: 327 IDVWMLVSMTFIFLSLLELAIVGYKTKNEEGSKKK 361 >UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subunit; n=2; Apis mellifera|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 469 Score = 98.3 bits (234), Expect = 2e-19 Identities = 49/155 (31%), Positives = 89/155 (57%), Gaps = 11/155 (7%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLACEIQ 53 D+ W++ P + ++ E+ L ++K++ + EI TT GN+S ++ + Sbjct: 169 DMVLYWDQEP--IILADELHLTEYKLVEKWVNSSEIFYTTSQQYYGHFAGNFSSISITFK 226 Query: 54 FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALP 113 R MG++++ YIPS LIV+ISWVSFWL+ +A+P R+ LG +LP Sbjct: 227 LAREMGFFMMDYYIPSILIVVISWVSFWLHMDASPPRIVLGTNTILTFMTLASKVENSLP 286 Query: 114 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 K+SY+K+ +++ C + +FA+++E+A V + +R Sbjct: 287 KVSYIKASEIWFLGCTIFLFAAMVEFAFVNTIYRR 321 >UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 494 Score = 97.9 bits (233), Expect = 2e-19 Identities = 47/153 (30%), Positives = 85/153 (55%), Gaps = 3/153 (1%) Query: 1 MRDIRYKWNEGPN--SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58 M +R W+E + ++ + ++++P + R + TG +S + R M Sbjct: 183 MTVLRLLWSEKEDVPAIDRNPDITMPDMSLKHIRTGYCNGTYATGEWSCMTAIFYVEREM 242 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 ++++Q Y+P+ LIV+ISW +FWL ++ PARVSL ALP++SY+ Sbjct: 243 MHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSLSITTLLTISTQANAVKLALPEVSYM 302 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM 151 K+IDV++G+C VF ++E+ T+ + AK ++M Sbjct: 303 KAIDVWMGSCMAFVFGVMIEF-TICHYAKNLEM 334 >UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p - Drosophila melanogaster (Fruit fly) Length = 612 Score = 97.1 bits (231), Expect = 4e-19 Identities = 49/142 (34%), Positives = 72/142 (50%) Query: 6 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65 Y+W ++V ++L QF ++ R G++S L R GY+LIQ+ Sbjct: 263 YEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQV 322 Query: 66 YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125 Y+P LIV++SWVSFW++R AT RVSL LPK+ Y ++D +L Sbjct: 323 YVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFL 382 Query: 126 GTCFVMVFASLLEYATVGYMAK 147 F+ A+LLE+A V Y K Sbjct: 383 LMSFLYCIATLLEFAGVHYFTK 404 >UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 405 Score = 97.1 bits (231), Expect = 4e-19 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Query: 3 DIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 D+ Y+W G V + SE + QF +LG R + + + G ++ L +F R M +Y Sbjct: 191 DVDYRWKGGETQGVEIVSE-EMAQFDLLGVRTDTKKSTNSKGAFASLKATFRFRRRMDFY 249 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 L IY+P ++V++SW +F++ +A PAR +L N+ +PK+SY+KSI Sbjct: 250 LSSIYVPEVILVVLSWTTFFITPSAVPARTALSITTILTTILLSSSVNSGMPKVSYMKSI 309 Query: 122 DVYLGTCFVMVFASLLEYATV 142 D ++ F +FA+L+EY V Sbjct: 310 DHFMLISFGFIFAALIEYIIV 330 >UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) protein 2, isoform a; n=3; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 2, isoform a - Caenorhabditis elegans Length = 546 Score = 95.9 bits (228), Expect = 1e-18 Identities = 44/142 (30%), Positives = 77/142 (54%), Gaps = 1/142 (0%) Query: 7 KWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIY 66 KW E + + +++ ++ + + +TG +S + E R + ++++Q Y Sbjct: 187 KWKED-EPITRNPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSY 245 Query: 67 IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126 +P+ LIV+ISW SFWL+ A PARVSL ALP++SY+K+IDV++G Sbjct: 246 VPTTLIVVISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMALPEVSYMKAIDVWMG 305 Query: 127 TCFVMVFASLLEYATVGYMAKR 148 C + VF ++E+ V Y ++ Sbjct: 306 ACMMFVFGVMIEFTIVNYAQRQ 327 >UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 95.9 bits (228), Expect = 1e-18 Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI Y+W + V + + + QF + + TG++S L ++ R +G+YL Sbjct: 134 DIVYQWAD--ERVTWAHDQEIAQFVLEKIETENLTRRYITGDFSALGIRLRLNRRLGHYL 191 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLG-XXXXXXXXXXXXXXNAALPKISYVKSI 121 ++Y+P+ LIV++SW+SF+L+R++ PARVSLG +LP +SYVK++ Sbjct: 192 TRVYVPAVLIVMLSWLSFYLDRHSAPARVSLGITTVLTMTTLLIGIGQGSLPVVSYVKAL 251 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 D YL + MVF + EYA + + K ++ +R Sbjct: 252 DWYLFVSYCMVFGAFAEYAVINHRDKSYFLKLRR 285 >UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit; n=3; Endopterygota|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 510 Score = 95.1 bits (226), Expect = 2e-18 Identities = 47/127 (37%), Positives = 66/127 (51%) Query: 21 VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSF 80 ++L QF ++G R + G +S L R GY+LIQ+Y+P LIV++SWVSF Sbjct: 207 MALSQFDLMGSPYRNLTFVRREGEFSVLQVSFNLQRHTGYFLIQVYVPCVLIVVLSWVSF 266 Query: 81 WLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYA 140 W++R AT RV LG LPK+ Y ++D +L F A+LLE+A Sbjct: 267 WIHREATSDRVGLGITTVLTLSTISLDSRTDLPKVRYATALDWFLLMSFGYCIATLLEFA 326 Query: 141 TVGYMAK 147 V Y K Sbjct: 327 GVHYFTK 333 >UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subunit; n=3; Endopterygota|Rep: Cys-loop ligand-gated ion channel subunit - Apis mellifera (Honeybee) Length = 391 Score = 95.1 bits (226), Expect = 2e-18 Identities = 51/159 (32%), Positives = 88/159 (55%), Gaps = 5/159 (3%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGH--RQRAMEISLT-TGNYSRLACEIQFVRSMGY 60 +R +W G +V V+ E+ L Q+ + + ++ L +GN+SRL +F R +G+ Sbjct: 144 LRLRWGTG--AVTVNPELKLLQYDIGKPVVAEETVDYMLEKSGNFSRLVVFFRFERQIGH 201 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 +LIQ + PS L+V++SW SFWL +A P RV+L + +P ++YVK+ Sbjct: 202 HLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGLKSDIPPVAYVKA 261 Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAV 159 +DV++ C + VFA+L E+ V + R Q+ T++ Sbjct: 262 LDVWMAGCMMFVFAALGEFVVVKVLDLRSQLEYDLQTSI 300 >UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 299 Score = 94.3 bits (224), Expect = 3e-18 Identities = 48/138 (34%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Query: 2 RDIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60 +DI+Y+W NS V V S +L QF + + GN +R+ F R +GY Sbjct: 163 QDIKYRWRPPMNSSVDVRSR-NLAQFALTSIIEVEYVEHYDLGNQNRMCVCFTFQRRLGY 221 Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120 +LIQ+YIPS +V++SW+ FW++++ R++LG NA++P++SY K+ Sbjct: 222 FLIQVYIPSIFVVVLSWIVFWMDKDNMGDRMALGITTVLTIMFLLGAVNASMPRVSYPKA 281 Query: 121 IDVYLGTCFVMVFASLLE 138 +D YL F +VF L+E Sbjct: 282 LDWYLMVSFTLVFLVLIE 299 >UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 443 Score = 93.5 bits (222), Expect = 5e-18 Identities = 49/156 (31%), Positives = 79/156 (50%), Gaps = 1/156 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI ++WN PN + + L QF + G+ GNY+ + + R +GYY+ Sbjct: 176 DIFFRWNN-PNKLSRVQKSDLAQFHLAGYDLITETGIYEEGNYTTVKVIFKMNRRVGYYI 234 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQ Y P LIV++SW+ FW++ R++LG NA++PK+SY K++D Sbjct: 235 IQAYCPDVLIVVLSWIIFWMDVKDMGDRMALGITTILTIMFLLGAVNASMPKVSYPKALD 294 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTA 158 YL F VF +L+E V + + + K + T+ Sbjct: 295 WYLMVSFAFVFLTLIESMIVFLLTPQGESEKPKKTS 330 >UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG02331 - Caenorhabditis briggsae Length = 472 Score = 93.1 bits (221), Expect = 7e-18 Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 5/157 (3%) Query: 3 DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFV----RS 57 ++R W + P ++ + LP F+ T G + +L F R Sbjct: 222 EVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFSFFFRFKRL 281 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 GYY++Q+Y+P+ L V ISW++FW++ A PAR++LG LP++S+ Sbjct: 282 YGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFGNIVKNLPRVSF 341 Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154 VK+ID++ C +F SL+E A VG++ K +++++ Sbjct: 342 VKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRR 378 >UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 93.1 bits (221), Expect = 7e-18 Identities = 47/152 (30%), Positives = 76/152 (50%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 +D+ Y W S + + QF ++ ++ + +S L + F R YY Sbjct: 152 KDLNYTWRSKVGSDIAIYDKEMAQFDIIAAKRFLKHPVYHSPMFSGLTATMSFRRRSLYY 211 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 + Q+YIP +VI+SW++FW++ RV LG NA +P++SY+KSI Sbjct: 212 IFQMYIPCTCVVILSWIAFWIDPKEGSERVGLGISAVLTISYMRGSMNAGMPRVSYLKSI 271 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRK 153 D +L FV VF SL+EY V A++ + +K Sbjct: 272 DYFLLISFVFVFMSLIEYVLVLKDARKERRKK 303 >UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subunit epsilon precursor (GABA(A) receptor subunit epsilon); n=30; Eutheria|Rep: Gamma-aminobutyric acid receptor subunit epsilon precursor (GABA(A) receptor subunit epsilon) - Homo sapiens (Human) Length = 506 Score = 93.1 bits (221), Expect = 7e-18 Identities = 41/140 (29%), Positives = 65/140 (46%) Query: 6 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65 YKW + + L QF G + I+ G++ + R GY Q Sbjct: 225 YKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQN 284 Query: 66 YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125 Y+PS + ++SWVSFW+ + PAR SLG P++SY+ ++D Y+ Sbjct: 285 YVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYI 344 Query: 126 GTCFVMVFASLLEYATVGYM 145 CFV F +LLE+A + ++ Sbjct: 345 AICFVFCFCALLEFAVLNFL 364 >UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory glycine receptor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to inhibitory glycine receptor - Strongylocentrotus purpuratus Length = 431 Score = 92.7 bits (220), Expect = 9e-18 Identities = 46/141 (32%), Positives = 76/141 (53%) Query: 18 SSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISW 77 S + LPQ+ + G G +S + + R++GYY++Q +IPS +V++SW Sbjct: 201 SHHMRLPQYYMTGVDFFDCTEQRYNGIFSCVRAQFTLERTLGYYMLQAFIPSIALVMVSW 260 Query: 78 VSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLL 137 V+FW++ A+PARV LG +P +SY+K+IDV+ +C V +LL Sbjct: 261 VTFWIDVRASPARVGLGVTIILSVISKTNGVRLDIPPVSYLKAIDVWYTSCLFFVIGALL 320 Query: 138 EYATVGYMAKRIQMRKQRFTA 158 EYA V +++ + KQ+ A Sbjct: 321 EYALVHHLSLGQKKTKQKVLA 341 >UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3).; n=2; Xenopus tropicalis|Rep: Gamma-aminobutyric-acid receptor subunit alpha-3 precursor (GABA(A) receptor subunit alpha-3). - Xenopus tropicalis Length = 465 Score = 92.7 bits (220), Expect = 9e-18 Identities = 39/106 (36%), Positives = 59/106 (55%) Query: 43 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102 G Y + R +GY++IQ Y+P + VI+S VSFWLNR + PAR G Sbjct: 233 GEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMT 292 Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR Sbjct: 293 TLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTKR 338 >UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop ligand-gated ion channel subunit; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cys-loop ligand-gated ion channel subunit - Nasonia vitripennis Length = 435 Score = 92.3 bits (219), Expect = 1e-17 Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Query: 11 GPNSVGVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYI 67 GP+ V V+ E+ L Q+ + L + I GN+SRL QF R +G++LIQ + Sbjct: 194 GPDGVIVNPELKLLQYNLEDPLKIDESVSFIDEKNGNFSRLIVYFQFERQIGHHLIQTFA 253 Query: 68 PSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGT 127 PS L+V++SW SFWL +A P RV+L + +P ++YVK++D+++ Sbjct: 254 PSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGLKSDIPPVAYVKALDLWMAG 313 Query: 128 CFVMVFASLLEYATV 142 C VF++L E+ V Sbjct: 314 CMFFVFSALGEFVVV 328 >UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA - Drosophila melanogaster (Fruit fly) Length = 524 Score = 92.3 bits (219), Expect = 1e-17 Identities = 40/106 (37%), Positives = 61/106 (57%) Query: 43 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102 GNYS L+ + R +G+YL+ ++PS LIV ISWVSFWL + P R++LG Sbjct: 246 GNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFI 305 Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 LPK+SY+K +V+ C + +F S++E+A V + +R Sbjct: 306 TLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRR 351 >UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine receptor family (See gbr) protein 3 - Caenorhabditis elegans Length = 438 Score = 92.3 bits (219), Expect = 1e-17 Identities = 46/158 (29%), Positives = 82/158 (51%), Gaps = 6/158 (3%) Query: 3 DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEI-----QFVR 56 ++R W + P ++ + LP F+ T G + +L +F R Sbjct: 187 EVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFSQTFYRFKR 246 Query: 57 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116 GYY++Q+Y+P+ L V ISW++FW++ A PAR++LG LP++S Sbjct: 247 LYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFGNIVKNLPRVS 306 Query: 117 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154 +VK+ID++ C +F SL+E A VG++ K +++++ Sbjct: 307 FVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRR 344 >UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 286 Score = 92.3 bits (219), Expect = 1e-17 Identities = 45/132 (34%), Positives = 70/132 (53%), Gaps = 2/132 (1%) Query: 11 GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSG 70 G + +S EV + Q+ + R + TG +S I R + YY+ Y+P+G Sbjct: 143 GGKGLIISDEVEISQYSITEVTSRDFKGVYNTGVFSEPIATIVLKRRLMYYVYGYYLPAG 202 Query: 71 LIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFV 130 L+V +SW+SFW++ + PARVSLG P +SY ++DVY+ +C+V Sbjct: 203 LVVFLSWISFWIDPRSVPARVSLGVITILAMGSFLHGGKG--PSVSYATALDVYIISCYV 260 Query: 131 MVFASLLEYATV 142 VF SLLE++ V Sbjct: 261 FVFTSLLEFSLV 272 >UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 290 Score = 92.3 bits (219), Expect = 1e-17 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Query: 19 SEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 78 S V LP+ + ++ ++ L GN+SR+ F R + Y L+QIY P+ LIV +SW+ Sbjct: 169 STVVLPRISI--YKSMSLNSVLFVGNWSRVTTTFLFKRQIEYALLQIYAPTMLIVSLSWL 226 Query: 79 SFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 138 SFW+++ A PARV+LG PK+SY+K+ID + FV VF + +E Sbjct: 227 SFWISKEAVPARVTLGVTTILTIVTLIGSFRFQFPKVSYIKAIDWFFIVSFVFVFGAQIE 286 Query: 139 YATV 142 + V Sbjct: 287 FIAV 290 >UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric acid A receptor, alpha 2 isoform 2; n=2; Euteleostomi|Rep: PREDICTED: gamma-aminobutyric acid A receptor, alpha 2 isoform 2 - Macaca mulatta Length = 403 Score = 91.9 bits (218), Expect = 2e-17 Identities = 38/104 (36%), Positives = 59/104 (56%) Query: 45 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104 Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR G Sbjct: 189 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 248 Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR Sbjct: 249 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 292 >UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 194 Score = 91.9 bits (218), Expect = 2e-17 Identities = 40/96 (41%), Positives = 63/96 (65%) Query: 65 IYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVY 124 IY+PS LIVI+SWVSFW++R T AR+++G +LPK+SYVKS++++ Sbjct: 1 IYLPSYLIVILSWVSFWVDREQTAARIAMGITTVLTMATLIGSARVSLPKVSYVKSLELF 60 Query: 125 LGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQ 160 L CF+ VF+++LEY+ V Y+ R +++ + A Q Sbjct: 61 LIMCFLFVFSAILEYSFVSYLVFRQRVKNREDYAQQ 96 >UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 349 Score = 91.9 bits (218), Expect = 2e-17 Identities = 52/156 (33%), Positives = 88/156 (56%), Gaps = 5/156 (3%) Query: 2 RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAM--EISLTTGNYSRLACEIQFVRSMG 59 ++I Y+W + P V V ++ +L QF + + + + EI GNYS L + F R +G Sbjct: 101 KNIVYRW-QSPLGVTVRNK-NLAQF-IFTYLELSEYEEIYGMMGNYSILQVDFAFKRRLG 157 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 Y+LIQ+Y P +V++SW+ FW++++ R++LG NAA+P++SY K Sbjct: 158 YFLIQVYAPDIFVVLLSWIVFWMDKDDMGNRMALGITTILTIMFLLGSVNAAMPRVSYPK 217 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155 ++D YL F +VF L+E V ++K R++R Sbjct: 218 ALDWYLMVSFSLVFLVLIECMIVFVISKYKNDRRKR 253 >UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila melanogaster|Rep: CG33989-PD, isoform D - Drosophila melanogaster (Fruit fly) Length = 737 Score = 91.5 bits (217), Expect = 2e-17 Identities = 42/145 (28%), Positives = 76/145 (52%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 I+Y W +++ S ++ ++ ++ A + + GNYS L E+ F R YY Sbjct: 490 IKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFT 549 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 ++IP ++V S+++FWL NA PARV +G + LP +S + +++V Sbjct: 550 TVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNV 609 Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148 + G C ++ASLLE+ V Y+ ++ Sbjct: 610 WDGVCMCFIYASLLEFVCVNYVGRK 634 >UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14573, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 371 Score = 91.1 bits (216), Expect = 3e-17 Identities = 37/92 (40%), Positives = 62/92 (67%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI + W G +V ++ LPQF ++ ++ + + +TG+Y RL+ + R++GY++ Sbjct: 232 DIEFYWRGGDGAVSGVDKIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRNIGYFI 291 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94 +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG Sbjct: 292 LQTYMPSILITILSWVSFWINYDASAARVALG 323 >UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 508 Score = 91.1 bits (216), Expect = 3e-17 Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 1/117 (0%) Query: 31 HRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR 90 H+ R E G + L +F R G+Y++Q Y+P+ L + ISW+SF L A PAR Sbjct: 245 HKIRTTE-EYPAGYWHELTMSFEFKRRAGWYILQAYLPTYLTICISWISFALGSKAIPAR 303 Query: 91 VSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147 LG LP++SYVK+IDV++ +C VF SLLE A VGY+++ Sbjct: 304 TMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWMLSCMTFVFCSLLELAWVGYLSR 360 >UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - Drosophila melanogaster (Fruit fly) Length = 449 Score = 91.1 bits (216), Expect = 3e-17 Identities = 51/165 (30%), Positives = 88/165 (53%), Gaps = 9/165 (5%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAME----ISLTTGNYSRLACEIQFVRSMG 59 ++ +W++ + V ++ E+ L Q+ LG E + GN+SRL +F R +G Sbjct: 191 VKLRWSD--SGVTLNPELKLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIG 247 Query: 60 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119 ++LIQ + PS L+V++SW SFWL +A P RV+L A +P ++YVK Sbjct: 248 HHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTL--LVTCMLTLVTMFTGADIPPVAYVK 305 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAV 164 ++D+++ C + VFA+L E+ V + + Q + R V M + Sbjct: 306 ALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRI 350 >UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila); n=3; Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like precursor (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) - Drosophila melanogaster (Fruit fly) Length = 686 Score = 90.6 bits (215), Expect = 4e-17 Identities = 43/103 (41%), Positives = 58/103 (56%) Query: 45 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104 YS L R MG +LIQ+Y P L+V++SWVSFWLNR AT RVSLG Sbjct: 378 YSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 437 Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147 LPK+SY ++D ++ F +FA++L++A V Y K Sbjct: 438 GLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTK 480 >UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 517 Score = 89.8 bits (213), Expect = 6e-17 Identities = 46/137 (33%), Positives = 66/137 (48%) Query: 17 VSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIIS 76 + E+ LP F + + G ++ L F R G+Y+ Q YIP+ L + IS Sbjct: 233 LKKEIVLPDFVMSNYSTSLKHEIYPAGVWNELTMTFVFSRRYGWYIFQAYIPTYLTIFIS 292 Query: 77 WVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 136 W+SF L PAR LG LP++SYVK++DV++ C VF SL Sbjct: 293 WISFCLGPKMIPARTMLGVNSLLALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFVFCSL 352 Query: 137 LEYATVGYMAKRIQMRK 153 LE A +G M R + R+ Sbjct: 353 LELAIIGSMGARSENRQ 369 >UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; Caenorhabditis|Rep: Serotonin-gated chloride channel - Caenorhabditis elegans Length = 489 Score = 89.4 bits (212), Expect = 8e-17 Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 2/145 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++ W E +V + + LP F ++ + + + G + +L F R G+Y+ Sbjct: 186 EVELHWME--EAVTLMKPIQLPDFDMVHYSTKKETLLYPNGYWDQLQVTFTFKRRYGFYI 243 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQ Y+P+ L +I+SWVSF + A PAR ++G LP++SYVK++D Sbjct: 244 IQAYVPTYLTIIVSWVSFCMEPKALPARTTVGISSLLALTFQFGNILKNLPRVSYVKAMD 303 Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147 V++ C VF +++E A V Y+++ Sbjct: 304 VWMLGCISFVFGTMVELAFVCYISR 328 >UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG11340-PA - Drosophila melanogaster (Fruit fly) Length = 526 Score = 89.0 bits (211), Expect = 1e-16 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 13/163 (7%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGH---------RQRAMEISLTTGNYSRLACEIQF 54 ++ W E N V ++ L ++ ++G + M GNYS ++ + Sbjct: 235 VQLHW-ETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLL 293 Query: 55 VRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPK 114 R +GYY+I ++PS +IV ISWVSFWL + TPAR +LG L K Sbjct: 294 TREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMK 353 Query: 115 ISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR---IQMRKQ 154 +SYV +V+ C + +F SL+E+A V + +R +Q++K+ Sbjct: 354 VSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKR 396 >UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6927-PA - Tribolium castaneum Length = 464 Score = 88.2 bits (209), Expect = 2e-16 Identities = 55/172 (31%), Positives = 92/172 (53%), Gaps = 16/172 (9%) Query: 7 KWNEGPNSVGVSSEVSLPQFKV------LGHRQ---RAMEISLTTGNYSRLACEIQFVRS 57 +WN+ S+ VS + +F V G + ++S G++S L + +F R Sbjct: 193 EWNKKSESLNVSDNLHFTEFIVDEIKCDTGTNDGPYQNRDMSDQVGSFSELVIKFRFHRD 252 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 +GYYL+ +IPS L+V +WV+FWL +A P R +LG + +PK+SY Sbjct: 253 IGYYLLDFFIPSYLLVCTAWVTFWLQADAGPPRATLGATTVVAFITLHLGMSKDIPKVSY 312 Query: 118 VKSIDV-YLG-TCFVMVFASLLEYATVGYMAKR---IQMRKQRFTAVQKMAV 164 +K+ D+ +LG +CF +F SL E+A V + +R I+++K + + K AV Sbjct: 313 IKASDIWFLGVSCF--IFFSLAEFAFVNVIWRRKKIIELKKPKQKYIIKAAV 362 >UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 428 Score = 87.0 bits (206), Expect = 4e-16 Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 6/147 (4%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++ +W + P + + + LP F + G +S L F R G+YL Sbjct: 212 EVFMRWGDPP--LTIFKPIELPDFTMTNFSTSNKFQLYAAGYWSELNVNFLFRRRSGWYL 269 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q YIP+ + V ISW+ F+L A PAR +G LP++SY+K+ID Sbjct: 270 LQGYIPTYMTVFISWIPFYLGPKAIPARTMIGVNALLALTFQFGNIIRNLPRVSYIKAID 329 Query: 123 VYL--GTCFVMVFASLLEYATVGYMAK 147 V++ G CF VFASL E AT+G++ + Sbjct: 330 VWMLSGICF--VFASLFELATIGFLMR 354 >UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG6927-PA - Tribolium castaneum Length = 534 Score = 85.8 bits (203), Expect = 1e-15 Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 7/147 (4%) Query: 8 WNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLT------TGNYSRLACEIQFVRSMGYY 61 W++ N V ++ + L +F + G + + + GN+S L + R +GYY Sbjct: 243 WDKN-NPVKIAKNLHLTEFVLSGSLPQETVVPASFNNGAFVGNFSELVFKFTLKREVGYY 301 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121 ++ ++PS L+V SWV+FWL +A+ RV+LG N LPK+SY+K+ Sbjct: 302 VMDYFLPSILLVCTSWVTFWLQADASAPRVTLGTSTMLAFITLNGGINKNLPKVSYIKAS 361 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKR 148 +++ C +F S+ E+A V + +R Sbjct: 362 EIWFLACACFIFCSMAEFAFVNVIWRR 388 >UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-aminobutyric acid receptor rho1 subunit; n=1; Bos taurus|Rep: PREDICTED: similar to gamma-aminobutyric acid receptor rho1 subunit - Bos taurus Length = 299 Score = 85.4 bits (202), Expect = 1e-15 Identities = 37/79 (46%), Positives = 51/79 (64%), Gaps = 1/79 (1%) Query: 77 WVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 136 WVSFW++R A PARV LG NA++P++SY+K++D+YL FV VF S+ Sbjct: 120 WVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSV 179 Query: 137 LEYATVGYMAKRIQMRKQR 155 LEYA V Y+ +Q RK+R Sbjct: 180 LEYAAVNYLT-TVQERKER 197 >UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1).; n=1; Gallus gallus|Rep: Gamma-aminobutyric-acid receptor subunit beta-1 precursor (GABA(A) receptor subunit beta-1). - Gallus gallus Length = 382 Score = 85.4 bits (202), Expect = 1e-15 Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 3/165 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 DI + WN G ++V S + LPQF ++ ++ + + TG Y +L+ R+ GY+ Sbjct: 106 DIEFYWNGGKSAVTGVSNIELPQFSIVDYKTVSKRVEFPTGTYPQLSLSFWLKRNTGYFT 165 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLG-XXXXXXXXXXXXXXNAALPKISYVKSI 121 +Q ++PS LI I+S VSFW+N +A+ ARV+LG + L K Sbjct: 166 LQTHMPSTLITILSRVSFWIN-DASAARVALGITTVLTMTTISTHLLSQMLGFFPQTKFK 224 Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR-FTAVQKMAVE 165 + ++ ++ L+YA G K M K R T + K+ VE Sbjct: 225 QITSTLPYIYIYLFKLDYAIKGSSCKDQSMNKVRHITEMSKLMVE 269 >UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopterygota|Rep: CG33989-PF, isoform F - Drosophila melanogaster (Fruit fly) Length = 779 Score = 85.4 bits (202), Expect = 1e-15 Identities = 39/145 (26%), Positives = 75/145 (51%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 I+Y W +++ S ++ ++ ++ A + + GNYS L ++ F R +Y Sbjct: 515 IKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDLIFTRDRAFYFT 574 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 ++IP ++V S+++FWL NA PAR +G + LP +S + +++V Sbjct: 575 TVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNV 634 Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148 + G C ++ASLLE+ V Y+ ++ Sbjct: 635 WDGVCMCFIYASLLEFVCVNYVGRK 659 >UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like protein T20B12.9; n=2; Caenorhabditis|Rep: Uncharacterized glycine receptor-like protein T20B12.9 - Caenorhabditis elegans Length = 476 Score = 85.0 bits (201), Expect = 2e-15 Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 2/140 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++R W++ P + + +V LP F ++G + G + R + F R G+YL Sbjct: 169 EVRLMWHDVP--ITMMEKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYL 226 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 Q Y P+ L VI SWV F+ + + AR++LG LP++SY+K +D Sbjct: 227 FQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLD 286 Query: 123 VYLGTCFVMVFASLLEYATV 142 V++ + +F +L+E A V Sbjct: 287 VWMIFSVIFIFCTLVELAIV 306 >UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 563 Score = 83.8 bits (198), Expect = 4e-15 Identities = 47/152 (30%), Positives = 81/152 (53%), Gaps = 7/152 (4%) Query: 4 IRYKWNEGPNS--VGVSSEVSLPQFKVLGHR--QRAMEISLTTGN--YSRLACEIQFVRS 57 + W + P + +G + ++ L ++ R + A + G +S + I R Sbjct: 276 VNLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKCAGPYPMFRGEAAWSCIQGYIVMKRL 335 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 + +++IQ YIP+G++V ISW+SFWL+ A+PAR+SL LP++SY Sbjct: 336 VLFHIIQTYIPTGMLVSISWMSFWLDPRASPARISLTITSLLTLTTMSNGARQDLPQVSY 395 Query: 118 VKSIDVYLGTCFVMVFASLLEYATVG-YMAKR 148 +K++D++L ++F LLEY+ V YM KR Sbjct: 396 IKALDIWLTFSQALIFLVLLEYSFVSYYMTKR 427 >UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.16; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T15B7.16 - Caenorhabditis elegans Length = 435 Score = 83.4 bits (197), Expect = 5e-15 Identities = 39/115 (33%), Positives = 65/115 (56%) Query: 47 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXX 106 +L + F R+ G+Y++Q+YIP+ V +S+VSFW++ A PAR++LG Sbjct: 247 QLTVSLTFSRAYGFYILQMYIPTYSSVFLSFVSFWIDLKALPARITLGVSSLMALTFQYG 306 Query: 107 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161 LP++ YVKSIDVY+ +F +++E A V Y+ +R++ A +K Sbjct: 307 NVAKNLPRVGYVKSIDVYMVLTTAFIFLTMIEVAFVCYLDSENNLRRKERQAEKK 361 >UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4; n=2; Apocrita|Rep: PH-sensitive chloride channel variant 4 - Apis mellifera (Honeybee) Length = 489 Score = 83.0 bits (196), Expect = 7e-15 Identities = 37/125 (29%), Positives = 65/125 (52%) Query: 43 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102 GNYS L ++ F R +Y ++IP ++V S+++FWL NA PARV +G Sbjct: 285 GNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFF 344 Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162 + LP +S + +++V+ G C ++ASLLE+ V Y+ ++ M + + Sbjct: 345 TTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPMHNVVYRPGENP 404 Query: 163 AVEKK 167 +K+ Sbjct: 405 VTQKR 409 >UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acc-4 - Caenorhabditis elegans Length = 408 Score = 82.6 bits (195), Expect = 1e-14 Identities = 44/132 (33%), Positives = 71/132 (53%), Gaps = 2/132 (1%) Query: 17 VSSEVSLPQFKVLGHRQRAMEISL-TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVII 75 + ++LP + VL + E+ L G ++ L F R G+Y++Q+Y+P+ + V I Sbjct: 220 LKGNITLPDY-VLVDFSSSSELRLYPPGIFNELIATFTFQRLYGFYILQVYVPAYISVFI 278 Query: 76 SWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFAS 135 SWVSF L P+R ++G LPK S VK+IDV++ + +FAS Sbjct: 279 SWVSFTLGAEQIPSRTTVGVNSLLALTFQFGAVVNNLPKTSDVKAIDVWILSSMAFIFAS 338 Query: 136 LLEYATVGYMAK 147 L+E A VGY+++ Sbjct: 339 LIELAVVGYLSR 350 >UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 428 Score = 82.6 bits (195), Expect = 1e-14 Identities = 40/115 (34%), Positives = 63/115 (54%) Query: 43 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102 GN+S + RS Y+L +Y S +IV ISW+ F + + T AR+++G Sbjct: 228 GNFSAVVAVFSIERSYTYFLTHVYGTSCVIVFISWMGFVIPPDQTAARIAVGVTTLLTQV 287 Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFT 157 N+++PK+SYVKSID +L +C + VF SL+EY + + + R Q+ T Sbjct: 288 TVINILNSSMPKVSYVKSIDKFLISCLIFVFLSLIEYCVILILDGKRTRRHQQHT 342 >UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF15015, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 201 Score = 80.2 bits (189), Expect = 5e-14 Identities = 33/88 (37%), Positives = 53/88 (60%), Gaps = 1/88 (1%) Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS-YVKSID 122 + Y+PS L+V++SWVSFW+++++ PAR +G +LP + ++K+ID Sbjct: 2 ETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAID 61 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQ 150 VYLG CF +F +LLEYA + + Q Sbjct: 62 VYLGICFTFIFGALLEYACAHFYTMQHQ 89 >UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 273 Score = 79.8 bits (188), Expect = 7e-14 Identities = 37/123 (30%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 +I YKW G +V V ++ L QF + M + TG++ + F R +GY++ Sbjct: 152 NIIYKWKTGKPAVEVGTK-DLAQFDMKTVEISNMTDTFVTGDFEAIIVTFTFKRRLGYFI 210 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 IQ++ P +V++SW+ FW++R R++LG N+++P++SY K++D Sbjct: 211 IQVFAPDIFVVMLSWIVFWMDREDMGNRMALGITIILTIMFLLGAINSSMPRVSYPKALD 270 Query: 123 VYL 125 YL Sbjct: 271 WYL 273 >UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 400 Score = 79.4 bits (187), Expect = 9e-14 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 3/160 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++R +WN + V E+ + F + ++ G + L F R +Y Sbjct: 225 EVRLQWNSQRSPVFALQEIRIADFWLKDITPAVIKRDYPAGLWDELVVTFVFERRYMWYF 284 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q Y+P+ + ISW++F L A R +G LP++SY+K+ID Sbjct: 285 LQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGSIMKNLPRVSYIKAID 344 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162 V++ + VF SL+E A VGY ++Q+++++ ++K+ Sbjct: 345 VWMLSSMTFVFLSLIELAIVGY---KLQIQREKEHVIEKV 381 >UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 93 Score = 79.4 bits (187), Expect = 9e-14 Identities = 33/93 (35%), Positives = 54/93 (58%) Query: 40 LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXX 99 + +G + + F R++GY L+Q+Y P+ LIV +SW++FW+ R+A PAR++L Sbjct: 1 IVSGAWIHITASFVFNRNIGYSLLQVYAPTTLIVALSWLAFWIPRDAVPARITLSVTTIL 60 Query: 100 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 132 PK+SYVK++DV+L F+ V Sbjct: 61 TIVTLMGSFRTQFPKVSYVKAVDVFLIVSFLFV 93 >UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor subunit rho-1 precursor (GABA(A) receptor subunit rho-1).; n=1; Takifugu rubripes|Rep: Gamma-aminobutyric-acid receptor subunit rho-1 precursor (GABA(A) receptor subunit rho-1). - Takifugu rubripes Length = 477 Score = 77.8 bits (183), Expect = 3e-13 Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61 D+ W G S+ + +SL QF + H + +TG Y+RL R + ++ Sbjct: 208 DLMLYWKSGDESLSIDDRISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFF 267 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94 L+Q Y P+ L+V++SWVSFW++R A PARVSLG Sbjct: 268 LLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 300 >UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG06736 - Caenorhabditis briggsae Length = 394 Score = 77.0 bits (181), Expect = 5e-13 Identities = 41/146 (28%), Positives = 64/146 (43%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++R +WN V + L F + + G + L F R +Y Sbjct: 219 EVRLQWNSQRKPVFAIQPIRLADFTLKDITTGTISRDYPAGKWDELIVTFVFERRYMWYF 278 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 +Q Y+P+ + ISW++F L A R +G LPK+SY+K+ID Sbjct: 279 LQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGSIMKNLPKVSYIKAID 338 Query: 123 VYLGTCFVMVFASLLEYATVGYMAKR 148 V++ + VF SL+E A VGY +R Sbjct: 339 VWMLGSMLFVFLSLVELAVVGYTLQR 364 >UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 536 Score = 76.6 bits (180), Expect = 6e-13 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%) Query: 3 DIRYKWNEGPNSVGVS----SEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58 +++YKW + GV S LPQF + G + YS L F R Sbjct: 217 EVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPANITRDKEYSALEVRFYFDRHF 276 Query: 59 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118 GY+L+ Y+P L+V++ WV+F+ R AT R+ +G + PK+ Sbjct: 277 GYFLMNFYVPCALVVLLCWVAFFTKREATAERIGIGITNVLTIVLISMDSKSDSPKVDSP 336 Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAK 147 +++V++ C++ ++E+ V Y K Sbjct: 337 TALEVFIWICYLTHLICMVEFTVVHYHTK 365 >UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 618 Score = 73.7 bits (173), Expect = 4e-12 Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 4/153 (2%) Query: 4 IRYKWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62 ++ +W N ++ + V +P+ + +G YS L + R +GY++ Sbjct: 402 VKLEWFSDTNDAIWIEKNVKIPELSIRHLHPDTCNGVRKSGVYSCLEAKFYMHREVGYHI 461 Query: 63 IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122 YIP+ + V+ SW+S WL R+ + LPK+SYVK+ID Sbjct: 462 ANTYIPTAICVVFSWISVWLPEEFVEGRIFVSLTVFLTLSAENNSAKEELPKVSYVKAID 521 Query: 123 VYLGTCFVMVFASLLEYATV---GYMAKRIQMR 152 ++ G VF ++L+ V + +KR++++ Sbjct: 522 IWFGFTSTFVFLTMLQALVVISLEHNSKRLRLK 554 >UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14565, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 502 Score = 71.3 bits (167), Expect = 2e-11 Identities = 35/115 (30%), Positives = 64/115 (55%), Gaps = 2/115 (1%) Query: 3 DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRA-MEISLTTGNYSRLACEIQFVRSMGYY 61 D+ W G +S+ + E+ L QF + + + + +TG Y+RL R + ++ Sbjct: 212 DLMLYWKNGNDSLR-TDEIVLSQFFIEQFQASSGLAFYSSTGWYNRLFISFLLRRHIFFF 270 Query: 62 LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116 ++Q Y P+ L+V++SWVSFW++R A PARVSLG ++++P+++ Sbjct: 271 MLQTYFPTMLMVVLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVSSSMPQVT 325 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/59 (42%), Positives = 37/59 (62%), Gaps = 7/59 (11%) Query: 114 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR-------FTAVQKMAVE 165 ++SYVK++D+YL T F++VF S++EYA V Y +MRK + F A Q MA + Sbjct: 358 QVSYVKAVDIYLWTSFLLVFLSVIEYAAVNYCTTLEEMRKMKRGKIPSTFNATQAMAFD 416 >UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 7 SCAF8790, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 66 Score = 69.3 bits (162), Expect = 1e-10 Identities = 28/54 (51%), Positives = 43/54 (79%) Query: 41 TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94 +TG+Y RL+ + R++GY+++Q Y+PS LI I+SWVSFW+N +A+ ARV+LG Sbjct: 1 STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 54 >UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Rep: GABA-A receptor - Caenorhabditis remanei Length = 206 Score = 66.5 bits (155), Expect = 7e-10 Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%) Query: 20 EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVS 79 +V LP+ + + +G +S L + R +G+++ Q YIP+ L ++ SWV Sbjct: 6 DVKLPELYIDRYETTTCANERKSGAFSCLRAVFRLKRDVGFHIAQTYIPTSLALMFSWVG 65 Query: 80 FWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE- 138 WL R+ + LP +SY+K+ID++ G VF +LL+ Sbjct: 66 VWLPEEFMEGRIGVAITVLLTLSTESAGAREHLPSVSYLKAIDLWFGFITGFVFFTLLQT 125 Query: 139 YATVGYMAKRIQMRK 153 +G+ + Q++K Sbjct: 126 LFVIGFDKRANQLKK 140 >UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 409 Score = 66.1 bits (154), Expect = 9e-10 Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 + + W +G N + + ++ L +F + ++++ G Y L F R +G+YLI Sbjct: 192 VAFHW-KGRNPITIFNK-ELSEFDMEQWLIEEVDMTYVAGKYRNLKVTFIFRRRLGFYLI 249 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117 Y+P ++VI+SW+ FW++ ++ R+SLG N+ +P++SY Sbjct: 250 NFYVPCVVMVIMSWIVFWMDSSSIGERISLGITTILTIVFLLGSSNSTMPRVSY 303 >UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 239 Score = 64.1 bits (149), Expect = 4e-09 Identities = 26/74 (35%), Positives = 41/74 (55%) Query: 43 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102 GNY+ L+ R +GYY IQ+Y+P +V++SW+ FW+N T R+++G Sbjct: 166 GNYTLLSASFPMHRRIGYYAIQMYVPCTFLVMLSWIVFWMNPEETGNRLTVGITTILTIV 225 Query: 103 XXXXXXNAALPKIS 116 N+ LPK+S Sbjct: 226 FLLGYTNSTLPKVS 239 >UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; Aedes aegypti|Rep: Glycine receptor beta, putative - Aedes aegypti (Yellowfever mosquito) Length = 439 Score = 54.8 bits (126), Expect = 2e-06 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 7/148 (4%) Query: 1 MRDIRYKWNEG-----PNSVGVSSEVSLPQFKVLGH-RQRAMEISLTTGNYSRLACEIQF 54 +R++R++W P G LP++ V + Q I N+S EI Sbjct: 141 VREMRFRWKNDNGLIFPKDFG-DGFFRLPKYVVSFYTEQNPQTIHYGEDNHSSARLEITL 199 Query: 55 VRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPK 114 R + YL++ Y+PS L V +SW SF + P R+ L P Sbjct: 200 SREVKSYLLENYLPSTLFVSMSWGSFVVVPEIVPGRMVLLVTTLLSLITMFDTVRNNSPD 259 Query: 115 ISYVKSIDVYLGTCFVMVFASLLEYATV 142 +K ++V+L +C + VF +L+EY V Sbjct: 260 ALELKCLEVWLISCTLFVFFALMEYFIV 287 >UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel ligand-binding; n=2; Chroococcales|Rep: Neurotransmitter-gated ion-channel ligand-binding - Crocosphaera watsonii Length = 340 Score = 54.4 bits (125), Expect = 3e-06 Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 2/128 (1%) Query: 16 GVSSEVSLPQFKVLG--HRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIV 73 G+SSE+SL + ++G A + +Y+R EI+ R +Y ++ P LIV Sbjct: 173 GISSEISLVNWSIIGLSSHSHAHYLQPEQQDYARFDYEIKVKRHSSFYAWRVLFPVALIV 232 Query: 74 IISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVF 133 +S + FWL +++L LPK++Y+ + D + ++VF Sbjct: 233 FMSDLVFWLEPTQIIPQITLATATMVSLITYQFILRQELPKMNYLTAEDKVIVGSMLLVF 292 Query: 134 ASLLEYAT 141 +L++ T Sbjct: 293 IALVKSVT 300 >UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; Roseobacter sp. AzwK-3b|Rep: Putative uncharacterized protein - Roseobacter sp. AzwK-3b Length = 244 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/98 (27%), Positives = 42/98 (42%) Query: 46 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXX 105 S L I R + YYL +I +P +V +SWV FW+ N ++ LG Sbjct: 108 SMLTLTISADREVNYYLFRIMLPLFFVVAMSWVIFWVPPNRFEFQIGLGATSMLTVIAFN 167 Query: 106 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 143 +LP + Y+ +D L +VF ++ E G Sbjct: 168 LAVAGSLPPLGYLTVLDQILIWSIAIVFLAIAEALVTG 205 >UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 343 Score = 50.4 bits (115), Expect = 5e-05 Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 4/135 (2%) Query: 16 GVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLI 72 G++ E+SLP + + H + I+ ++ E++ R YY+ ++ +P LI Sbjct: 178 GLAEEISLPNWSTNIPVAHNG-SRHIAQLNQSFVCFDYELKVKRYTAYYITRVILPLILI 236 Query: 73 VIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 132 V++S+ FW +V++ +LP++ Y+ +D ++ V+V Sbjct: 237 VLMSYAVFWFPPGQIMPQVTISVTAILSLITYEFTLQQSLPQVPYLTVLDKFVIGAMVLV 296 Query: 133 FASLLEYATVGYMAK 147 F +L+E T +A+ Sbjct: 297 FLALVETVTTIELAE 311 >UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit precursor; n=3; Chromadorea|Rep: Ligand-gated chloride channel subunit precursor - Dirofilaria immitis (Canine heartworm) Length = 406 Score = 50.0 bits (114), Expect = 6e-05 Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 1 MRDIRYKWNEGPNSV---GVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57 + DI Y W P +V VS E+ ++ + T G YS + I F + Sbjct: 189 IEDIVYLWANSPPTVIPVEVSQELLTGFYEFKEAVAEDCAGNYTIGIYSCIDVLITFTGA 248 Query: 58 MGYYLIQIYIPSGLIVIISWVSFWLNRN-ATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116 +I+IPS L++++SW+ FW++ + + P +S L Sbjct: 249 SSEAFWRIFIPSILLILVSWLHFWVHGSWSVPRTISAAVPFLIFVSILIFYPQPNLTTYG 308 Query: 117 YVKSIDVYLGTCFVMVFASLLEYATV 142 V S+ ++L C + FASL+EY V Sbjct: 309 -VSSLQIWLFFCLIFTFASLVEYFIV 333 >UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1; Drosophila sp.|Rep: Gamma-aminobutyric acid A receptor - Drosophila sp. (Fruit fly) Length = 210 Score = 49.6 bits (113), Expect = 8e-05 Identities = 34/63 (53%), Positives = 39/63 (61%), Gaps = 11/63 (17%) Query: 33 QRAMEISLTTGNYSRLACEIQ-FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARV 91 QRA EI+LTTGNYSRLACEIQ FV M + + Y G + RNATPARV Sbjct: 106 QRATEINLTTGNYSRLACEIQCFV--MVFASLLEYATVGYMA--------KRRNATPARV 155 Query: 92 SLG 94 +LG Sbjct: 156 ALG 158 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/21 (100%), Positives = 21/21 (100%) Query: 128 CFVMVFASLLEYATVGYMAKR 148 CFVMVFASLLEYATVGYMAKR Sbjct: 127 CFVMVFASLLEYATVGYMAKR 147 >UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; Danio rerio|Rep: glycine receptor, beta b - Danio rerio Length = 451 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/34 (58%), Positives = 26/34 (76%) Query: 112 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 145 LPK+SYVK+ID++L C + FASL+EYA V M Sbjct: 276 LPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVM 309 >UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 394 Score = 42.3 bits (95), Expect = 0.013 Identities = 23/93 (24%), Positives = 37/93 (39%) Query: 45 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104 +S + R GYYL +I IP +IV +W +FW+ R+ Sbjct: 257 FSEYVYSVNVDRDPGYYLYKIVIPLLIIVAFNWATFWMPGEPASVRMERTVIALLTVVAF 316 Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLL 137 LP+I Y+ +D + F V ++L Sbjct: 317 HQVVATNLPRIGYLTFMDGIVYVAFASVGLTML 349 >UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Glra4a protein - Strongylocentrotus purpuratus Length = 541 Score = 41.1 bits (92), Expect = 0.029 Identities = 22/75 (29%), Positives = 38/75 (50%) Query: 56 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKI 115 R G+Y+ I + LIVI+++ SF + R A R+S+ + +LP I Sbjct: 299 RRPGFYIWNIALIMLLIVILTFTSFVVERGAPADRLSVTVTLLLTAVAFKYVVSQSLPLI 358 Query: 116 SYVKSIDVYLGTCFV 130 SY+ +D Y+ +C + Sbjct: 359 SYLTMLDKYVLSCLI 373 >UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome undetermined SCAF15016, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 269 Score = 39.9 bits (89), Expect = 0.067 Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 1/35 (2%) Query: 111 ALPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGY 144 +LP + ++K+IDVYLG CF +F +L+EYA + Sbjct: 232 SLPNANCFIKAIDVYLGICFSFIFGALIEYAVAHF 266 >UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 679 Score = 38.7 bits (86), Expect = 0.15 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 4/145 (2%) Query: 4 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63 +++ W+ P + S+++LP+ + + + S L R ++I Sbjct: 472 VKFHWHSNP--IKFQSKITLPELHITKIKTAECSTKGKLVDASCLRIIFSLERDSARFVI 529 Query: 64 QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123 + Y+PS L ++ +WV+ ++ N R+ + SY+ SIDV Sbjct: 530 EKYVPSTLAMMFAWVAPYVPYNYEDVRIITPITVLLTLVQMEKGDKEI--RTSYLTSIDV 587 Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148 + SLLE V + KR Sbjct: 588 WFAAMKSFTVLSLLESLAVLALIKR 612 >UniRef50_A7I712 Cluster: Putative uncharacterized protein precursor; n=1; Candidatus Methanoregula boonei 6A8|Rep: Putative uncharacterized protein precursor - Methanoregula boonei (strain 6A8) Length = 337 Score = 38.7 bits (86), Expect = 0.15 Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 9/135 (6%) Query: 13 NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFVRSMGYYLIQIYIPSG 70 N+ G+ E +LP + + G + G YSR+ R L++ ++P Sbjct: 167 NNTGLDDEANLPGWSLTGMSAEVTNRTYVEGEVPYSRVTFSNGIERDTASTLLKFFLPIT 226 Query: 71 LIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFV 130 LI+I+S S + T +R+ L A+P ++Y +D+++ + Sbjct: 227 LIIIVSLASLLMK---TSSRLGLNGSMFLAAVLIHWRIADAIPLVAYATFLDLFM----I 279 Query: 131 MVFASLLEYATVGYM 145 + +A+L+ G + Sbjct: 280 ITYATLVMVCVSGIL 294 >UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to nicotinic acetylcholine receptor beta 1 subunit variant 1 - Strongylocentrotus purpuratus Length = 472 Score = 38.3 bits (85), Expect = 0.20 Identities = 16/39 (41%), Positives = 25/39 (64%) Query: 44 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL 82 NYS++ EI R Y++I + +PS LI +S V+FW+ Sbjct: 218 NYSKIHFEITLTRKSYYFVINLVLPSSLINAMSLVAFWV 256 >UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; Synechococcus sp. WH 7805|Rep: Putative uncharacterized protein - Synechococcus sp. (strain WH7805) Length = 386 Score = 37.1 bits (82), Expect = 0.47 Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 5/122 (4%) Query: 15 VGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL 71 V +S LP++K+ R + + + +SRL+ I R GYY+ +I++P G+ Sbjct: 216 VSLSRNARLPEWKIKDLRYVIKNHDDPEKGSKEFSRLSSTITISRRSGYYIYKIFLPLGI 275 Query: 72 IVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVM 131 + S + +A R++ +++P++ Y+ D Y T F+ Sbjct: 276 LTFTSIFFLAIPIDAFADRMAFISGLLFTTLAYQIIIASSVPRVPYLTLGDTY--TIFLF 333 Query: 132 VF 133 F Sbjct: 334 TF 335 >UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter violaceus|Rep: Glr4197 protein - Gloeobacter violaceus Length = 359 Score = 36.7 bits (81), Expect = 0.62 Identities = 26/119 (21%), Positives = 46/119 (38%), Gaps = 3/119 (2%) Query: 46 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXX 105 S+L +++ R Y+ I +P I+ ISW +FW + A V+L Sbjct: 224 SKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLVVSTLIAHIAFN 281 Query: 106 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQ-MRKQRFTAVQKMA 163 LPK Y+ + ++ F +++E Y+ Q R T ++A Sbjct: 282 ILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIA 340 >UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform b; n=4; Caenorhabditis|Rep: Acetylcholine receptor protein 17, isoform b - Caenorhabditis elegans Length = 515 Score = 36.7 bits (81), Expect = 0.62 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 5/93 (5%) Query: 56 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVSLGXXXXXXXXXXXXXXNAAL 112 R+ YYL + IPS I I++ + F+ ++T +VSLG + L Sbjct: 243 RNPSYYLFTLIIPSAFITIVTVIGFFTPHSSTGENTEKVSLGVTALLSLAIILMMVSDKL 302 Query: 113 PKISYVKSI--DVYLGTCFVMVFASLLEYATVG 143 P S + Y+G F+M A+ T+G Sbjct: 303 PATSNSVPLLGQYYIGLIFIMFLATYCTTFTLG 335 >UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18; n=2; Caenorhabditis|Rep: Putative uncharacterized protein acr-18 - Caenorhabditis elegans Length = 510 Score = 36.7 bits (81), Expect = 0.62 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 56 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVSLGXXXXXXXXXXXXXXNAAL 112 RS YY+ + IPS I +++ V F+ + T +VSLG + + Sbjct: 235 RSPSYYIFSLVIPSAFITVVTIVGFFTPHSTTGENTEKVSLGVTALLSMAIIMMMVSDEV 294 Query: 113 PKISYVKSI--DVYLGTCFVMVFASLLEYATVGYMAK 147 P S V + Y+G F++ A+ T+ Y + Sbjct: 295 PATSEVIPLIGKYYIGLIFLIFMAAFTTTLTLSYQMR 331 >UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuronal acetylcholine receptor subunit alpha-9 precursor - Strongylocentrotus purpuratus Length = 510 Score = 36.3 bits (80), Expect = 0.82 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 9 NEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYI 67 NE PN SV + + V Q V + T YS++ E+ RS G+Y++ I + Sbjct: 258 NEDPNQSVFLQNGVWSLQNSVAHQKNETYACCETP--YSQIVYELILERSYGFYVLNIVL 315 Query: 68 PSGLIVIISWVSFWL 82 PSGL+ ++ + F L Sbjct: 316 PSGLLAFVNCLVFLL 330 >UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E; n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor 3E - Homo sapiens (Human) Length = 471 Score = 36.3 bits (80), Expect = 0.82 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 8/117 (6%) Query: 25 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 82 ++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288 Query: 83 -NRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 138 + N P +++L + LP S I VY C ++ SLLE Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340 >UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 404 Score = 35.9 bits (79), Expect = 1.1 Identities = 19/86 (22%), Positives = 39/86 (45%) Query: 51 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNA 110 E F R+ G+Y++ + IP+ I ++S V+ +++ N + ++G Sbjct: 254 EATFSRNPGFYIVLVMIPAYFINVLSIVALFMDINNRSEKFTVGMTNIMSMSFILVILAE 313 Query: 111 ALPKISYVKSIDVYLGTCFVMVFASL 136 LPK + + +Y T ++ SL Sbjct: 314 DLPKTKNLPILAIYTVTSLAIMLCSL 339 >UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine receptor 3 subunit D - Xenopus tropicalis Length = 415 Score = 35.1 bits (77), Expect = 1.9 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 61 YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY-VK 119 Y++ + +PS +++I +SF+L ++T R S N LP + Sbjct: 196 YVVNLLVPSAFLMLIDILSFFLPPHSTD-RASFKMTLLLGYTVFLLIMNDLLPSTANGTP 254 Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 152 I +Y C ++ SLLE + ++ R M+ Sbjct: 255 LIGIYFSVCLALLVLSLLETVIITHVMHRGAMQ 287 >UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2; Caenorhabditis elegans|Rep: Ligand-gated ion channel protein 1 - Caenorhabditis elegans Length = 371 Score = 34.7 bits (76), Expect = 2.5 Identities = 22/113 (19%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Query: 43 GNYSRLACEIQFV-RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXX 101 GN+S + + + R+ G+Y+ + +P+ I +S ++ LN ++++G Sbjct: 218 GNFSAVQRFVARIERNPGFYVTLVMVPAFFINFLSIIALCLNIENVGEKITVGLTNIMAM 277 Query: 102 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154 LPK + + +Y+ V+V AS+ T+ + ++ R++ Sbjct: 278 TFILVILAQDLPKTKRIPLLAIYVIVGLVIVMASIGVVLTLPLIRNHLKKRQK 330 >UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alternative variant a; n=5; Caenorhabditis|Rep: Acetylcholine receptor 20 (63.9 kD) alternative variant a - Caenorhabditis elegans Length = 553 Score = 34.3 bits (75), Expect = 3.3 Identities = 23/109 (21%), Positives = 48/109 (44%), Gaps = 4/109 (3%) Query: 44 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR---VSLGXXXXXX 100 NY+ L + R YY+I + IP+ +I IS + F+ + R ++LG Sbjct: 224 NYTLLEFRLTIQRKPLYYIINLIIPTSIITFISIIGFFSTSSINEPREEKITLGFTTLLS 283 Query: 101 XXXXXXXXNAALPKI-SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148 + +P S++ I ++ + +++ S + + V Y+ K+ Sbjct: 284 MSILIFMVSDKMPSTSSFIPLIGLFYTSMILLISFSTICSSVVIYVQKQ 332 >UniRef50_UPI00006CC8B0 Cluster: hypothetical protein TTHERM_00290740; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00290740 - Tetrahymena thermophila SB210 Length = 679 Score = 33.9 bits (74), Expect = 4.4 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 113 PKISYVKSIDVYLGTCF-VMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVE 165 PK + KS+ +L C +L ATVG+ K I++ KQR AVQK+ + Sbjct: 336 PKKDFQKSLYSFLLACQDFRDLQIILAKATVGFWKKSIELEKQRSKAVQKIVTD 389 >UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG10413 - Caenorhabditis briggsae Length = 366 Score = 33.9 bits (74), Expect = 4.4 Identities = 19/95 (20%), Positives = 43/95 (45%) Query: 53 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAAL 112 +F R+ G+Y+ + +P+ I +S + ++N ++++G A L Sbjct: 248 RFQRNPGFYVALVMVPAFFINFLSIFALFVNVENLSEKITVGLTNIMAMTFILVILAADL 307 Query: 113 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147 PK + + + +Y+ V+V S+ + Y+ K Sbjct: 308 PKTARIPLLAIYVIVGLVIVMTSIGICLLIPYIRK 342 >UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1; Bacteroides thetaiotaomicron|Rep: Putative uncharacterized protein - Bacteroides thetaiotaomicron Length = 537 Score = 33.5 bits (73), Expect = 5.8 Identities = 15/49 (30%), Positives = 27/49 (55%) Query: 11 GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMG 59 G + VG+ + +P+ K GH+ + I+ T+ Y A E+ F+R+ G Sbjct: 324 GQDYVGMRRGIVIPELKTTGHKYSGVNIAPTSPLYWMNAAEVAFLRAEG 372 >UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep: Slr0882 protein - Synechocystis sp. (strain PCC 6803) Length = 394 Score = 33.5 bits (73), Expect = 5.8 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%) Query: 21 VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFV--RSMGYYLIQIYIPSGLI-VIISW 77 + +P+F VL + SL YSRL+ + + + RS+G + ++ +P+ L ++++ Sbjct: 75 LKMPEFVVLAFPMSMLLASLMA--YSRLSSDSELIALRSIGVSIYRLVVPALLFGIVVTG 132 Query: 78 VSFWLNRNATPA 89 ++F N TPA Sbjct: 133 IAFVFNDRITPA 144 >UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-type des-2 precursor; n=2; Caenorhabditis|Rep: Acetylcholine receptor subunit alpha-type des-2 precursor - Caenorhabditis elegans Length = 548 Score = 33.5 bits (73), Expect = 5.8 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 5/87 (5%) Query: 13 NSVGVSSEVSLPQFKVLGHRQRAMEISLTT--GNYSRLACEIQFVRSMGYYLIQIYIPSG 70 + +G S+ + + +L + + E+ NY+ L + R +YL+ + IP+ Sbjct: 191 DKIGTSNYLENEGWYILQTKIKRQEVKYACCPNNYTLLQLTLYLRRKPLFYLVNLIIPTS 250 Query: 71 LIVIISWVSFWLNRNATPAR---VSLG 94 +I +I+ V F+ +A+ R VSLG Sbjct: 251 IITLIAIVGFFTTSSASGMREEKVSLG 277 >UniRef50_Q70Z44 Cluster: 5-hydroxytryptamine receptor 3 family member D; n=7; Eutheria|Rep: 5-hydroxytryptamine receptor 3 family member D - Homo sapiens (Human) Length = 454 Score = 33.1 bits (72), Expect = 7.7 Identities = 14/60 (23%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Query: 25 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM--GYYLIQIYIPSGLIVIISWVSFWL 82 ++ +LG ++R +++++ T Y + + R Y++ +PSG+++ I +SF+L Sbjct: 194 EWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYL 253 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.323 0.136 0.405 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 240,135,259 Number of Sequences: 1657284 Number of extensions: 7638760 Number of successful extensions: 15112 Number of sequences better than 10.0: 149 Number of HSP's better than 10.0 without gapping: 134 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 14946 Number of HSP's gapped (non-prelim): 154 length of query: 269 length of database: 575,637,011 effective HSP length: 99 effective length of query: 170 effective length of database: 411,565,895 effective search space: 69966202150 effective search space used: 69966202150 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (22.0 bits) S2: 72 (33.1 bits)
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