SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000641-TA|BGIBMGA000641-PA|IPR006201|Neurotransmitter-
gated ion-channel, IPR006028|Gamma-aminobutyric acid A receptor,
IPR002289|Gamma-aminobutyric-acid A receptor, beta subunit,
IPR013838|Beta tubulin, autoregulation binding site,
IPR006202|Neurotransmitter-gated ion-channel ligand-binding,
IPR006029|Neurotransmitter-gated ion-channel transmembrane region
         (269 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni...   290   3e-77
UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1...   242   6e-63
UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae...   215   1e-54
UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49...   146   5e-34
UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni...   142   6e-33
UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated...   137   2e-31
UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve...   137   3e-31
UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni...   136   6e-31
UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta...   134   2e-30
UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur...   134   3e-30
UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subuni...   133   5e-30
UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea...   132   1e-29
UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh...   131   2e-29
UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ...   130   3e-29
UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve...   129   6e-29
UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin...   128   1e-28
UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-...   127   3e-28
UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur...   126   4e-28
UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subuni...   126   4e-28
UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride...   125   1e-27
UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella ve...   125   1e-27
UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromado...   124   2e-27
UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subuni...   120   5e-26
UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;...   118   2e-25
UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protei...   118   2e-25
UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg...   117   4e-25
UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella ve...   116   8e-25
UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni...   116   8e-25
UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni...   115   1e-24
UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated...   113   4e-24
UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol...   113   6e-24
UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ...   112   1e-23
UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl...   111   1e-23
UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni...   110   3e-23
UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve...   110   4e-23
UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni...   110   4e-23
UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve...   109   6e-23
UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni...   109   6e-23
UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni...   109   6e-23
UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni...   109   7e-23
UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; ...   109   1e-22
UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated...   108   1e-22
UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella ve...   108   2e-22
UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve...   107   2e-22
UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac...   107   3e-22
UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli...   105   9e-22
UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella ve...   105   1e-21
UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella ve...   105   1e-21
UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ...   104   2e-21
UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 pr...   104   2e-21
UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protei...   103   4e-21
UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; R...   103   4e-21
UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve...   103   4e-21
UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella ve...   103   6e-21
UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve...   102   1e-20
UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop l...   101   1e-20
UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; ...   101   1e-20
UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;...   101   1e-20
UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor...   101   2e-20
UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve...    99   6e-20
UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7...   100   8e-20
UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella ve...   100   8e-20
UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ...    99   1e-19
UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ...    98   2e-19
UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subun...    98   2e-19
UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; ...    98   2e-19
UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125...    97   4e-19
UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella ve...    97   4e-19
UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ...    96   1e-18
UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella ve...    96   1e-18
UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun...    95   2e-18
UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subun...    95   2e-18
UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve...    94   3e-18
UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve...    93   5e-18
UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023...    93   7e-18
UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve...    93   7e-18
UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subuni...    93   7e-18
UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory...    93   9e-18
UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor...    93   9e-18
UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop l...    92   1e-17
UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ...    92   1e-17
UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ...    92   1e-17
UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve...    92   1e-17
UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve...    92   1e-17
UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric ac...    92   2e-17
UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella ve...    92   2e-17
UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve...    92   2e-17
UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ...    91   2e-17
UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh...    91   3e-17
UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ...    91   3e-17
UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - ...    91   3e-17
UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-...    91   4e-17
UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ...    90   6e-17
UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ...    89   8e-17
UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134...    89   1e-16
UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;...    88   2e-16
UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ...    87   4e-16
UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;...    86   1e-15
UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-amin...    85   1e-15
UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor...    85   1e-15
UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopteryg...    85   1e-15
UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p...    85   2e-15
UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ...    84   4e-15
UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7....    83   5e-15
UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4...    83   7e-15
UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;...    83   1e-14
UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella ve...    83   1e-14
UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome sh...    80   5e-14
UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve...    80   7e-14
UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ...    79   9e-14
UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ...    79   9e-14
UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor...    78   3e-13
UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067...    77   5e-13
UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ...    77   6e-13
UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; ...    74   4e-12
UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whol...    71   2e-11
UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome sho...    69   1e-10
UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Re...    66   7e-10
UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve...    66   9e-10
UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve...    64   4e-09
UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; A...    55   2e-06
UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga...    54   3e-06
UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; ...    52   2e-05
UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit p...    50   6e-05
UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1...    50   8e-05
UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D...    46   0.001
UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; ...    42   0.013
UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a pro...    41   0.029
UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol...    40   0.067
UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ...    39   0.15 
UniRef50_A7I712 Cluster: Putative uncharacterized protein precur...    39   0.15 
UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ...    38   0.20 
UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; ...    37   0.47 
UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola...    37   0.62 
UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof...    37   0.62 
UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18...    37   0.62 
UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a...    36   0.82 
UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ...    36   0.82 
UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ...    36   1.1  
UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s...    35   1.9  
UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2...    35   2.5  
UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt...    34   3.3  
UniRef50_UPI00006CC8B0 Cluster: hypothetical protein TTHERM_0029...    34   4.4  
UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104...    34   4.4  
UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1; ...    33   5.8  
UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep...    33   5.8  
UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty...    33   5.8  
UniRef50_Q70Z44 Cluster: 5-hydroxytryptamine receptor 3 family m...    33   7.7  

>UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit
           beta precursor (GABA(A) receptor subunit beta); n=45;
           Pancrustacea|Rep: Gamma-aminobutyric acid receptor
           subunit beta precursor (GABA(A) receptor subunit beta) -
           Drosophila melanogaster (Fruit fly)
          Length = 606

 Score =  290 bits (711), Expect = 3e-77
 Identities = 139/171 (81%), Positives = 149/171 (87%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           MRDIRY W +G +SVG+SSEV LPQF+VLGHRQRA EI+LTTGNYSRLACEIQFVRSMGY
Sbjct: 210 MRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGY 269

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YLIQIYIPSGLIVIISWVSFWLNRNATPARV+LG              NAALPKISYVKS
Sbjct: 270 YLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKS 329

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQID 171
           IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF A+QK+A +KK Q+D
Sbjct: 330 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380


>UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1b;
           n=8; Pancrustacea|Rep: Ionotropic GABA receptor beta
           subunit 1b - Homarus americanus (American lobster)
          Length = 521

 Score =  242 bits (593), Expect = 6e-63
 Identities = 116/167 (69%), Positives = 130/167 (77%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           M  IR  W+ G  SV + S+VSLPQF+VLG+ ++ +  S +TGNYSRL CEI FVRSMGY
Sbjct: 235 MDHIRLSWHAGDRSVVIESDVSLPQFRVLGYNRKTIISSTSTGNYSRLLCEIMFVRSMGY 294

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YLIQIYIPS LIV+ISWVSFWLNR+ATPARVSLG              NAALPKISYVKS
Sbjct: 295 YLIQIYIPSSLIVVISWVSFWLNRSATPARVSLGVTTVLTMTTLMSSTNAALPKISYVKS 354

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167
           IDVYLGTCFVMVFASLLEYA VGYM KRIQMRK R  A+QKMA ++K
Sbjct: 355 IDVYLGTCFVMVFASLLEYAAVGYMGKRIQMRKNRILAIQKMAEQRK 401


>UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus
           urticae|Rep: GABA receptor - Tetranychus urticae
           (Two-spotted spider mite)
          Length = 585

 Score =  215 bits (525), Expect = 1e-54
 Identities = 105/167 (62%), Positives = 120/167 (71%), Gaps = 1/167 (0%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           M DI Y W +  N+V + S + LPQF +   RQ    ISLTTGNYSRL CEIQ  RSMGY
Sbjct: 197 MTDIIYNWVD-ENAVKIDSNLMLPQFSIASIRQSWKYISLTTGNYSRLMCEIQLTRSMGY 255

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           Y+IQIY+P+ LIVIISWVSFWL+RNATPARV LG              N+ LPKISYVKS
Sbjct: 256 YMIQIYVPASLIVIISWVSFWLHRNATPARVHLGVITVLTMTTLMSSTNSQLPKISYVKS 315

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167
           IDV+LGTCFVMVFA+LLEYA VGY+ KRI MRK RF  + K A EK+
Sbjct: 316 IDVFLGTCFVMVFAALLEYAAVGYIGKRISMRKNRFQQLAKAAEEKR 362


>UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit
           UNC-49B.3; n=11; Eumetazoa|Rep: Ionotropic GABA receptor
           subunit UNC-49B.3 - Caenorhabditis elegans
          Length = 506

 Score =  146 bits (354), Expect = 5e-34
 Identities = 72/158 (45%), Positives = 98/158 (62%), Gaps = 4/158 (2%)

Query: 2   RDIRYKWNEGPNSVGVSS----EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57
           +DI Y W +    + +++       LPQF+   +     +   ++G Y RLA E+  VR+
Sbjct: 193 KDIDYYWGKKRTDLEITAVKFDTFQLPQFQPTLYFVNTTKAETSSGKYVRLALEVILVRN 252

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
           MG+Y + I IPS LIV ISWVSFWLNR A+PARV LG              N ++PK+SY
Sbjct: 253 MGFYTMNIVIPSILIVTISWVSFWLNREASPARVGLGVTTVLTMTTLITTTNNSMPKVSY 312

Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           VK +DV+L  CFVMVFASLLEYA V YM KR+ +R+++
Sbjct: 313 VKGLDVFLNFCFVMVFASLLEYAIVSYMNKRLVLRREK 350


>UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit
           beta-1 precursor (GABA(A) receptor subunit beta-1);
           n=104; Euteleostomi|Rep: Gamma-aminobutyric acid
           receptor subunit beta-1 precursor (GABA(A) receptor
           subunit beta-1) - Homo sapiens (Human)
          Length = 474

 Score =  142 bits (345), Expect = 6e-33
 Identities = 72/175 (41%), Positives = 107/175 (61%), Gaps = 6/175 (3%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI + WN G  +V   +++ LPQF ++ ++  + ++  TTG Y RL+   +  R++GY++
Sbjct: 188 DIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFI 247

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG                 LPKI YVK+ID
Sbjct: 248 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307

Query: 123 VYLGTCFVMVFASLLEYATVGYM--AKRIQMR---KQRFTAVQKMAVE-KKIQID 171
           +YL  CFV VF +LLEYA V Y+   K  Q +   KQ  +A +K  +E  K+Q+D
Sbjct: 308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVD 362


>UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated
           ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to GABA-gated ion channel - Nasonia vitripennis
          Length = 513

 Score =  137 bits (332), Expect = 2e-31
 Identities = 70/165 (42%), Positives = 98/165 (59%), Gaps = 5/165 (3%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+   W E P   GV  E  LPQF ++G+     +  L TG Y RL+   +  R++GY++
Sbjct: 202 DVVMSWKETPVR-GVD-EAKLPQFTIIGYETNDRKEKLATGIYQRLSLSFKLQRNIGYFV 259

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
            Q Y+PS LIV++SWVSFW+N  AT ARV+LG               ++LP+ISYVK+ID
Sbjct: 260 FQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAID 319

Query: 123 VYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFTAVQKMAV 164
           +YL  CFV VFA+LLEYA V Y    A+  +  K++ T  +K  +
Sbjct: 320 IYLVMCFVFVFAALLEYAAVNYTYWGARAKKKSKKKETEEEKKTI 364


>UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 278

 Score =  137 bits (331), Expect = 3e-31
 Identities = 63/144 (43%), Positives = 93/144 (64%), Gaps = 2/144 (1%)

Query: 3   DIRYKWNE--GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           ++ +KWN+  G   V VS E+ +PQF +  ++  +   + TTG+YSRL    +F RS+G+
Sbjct: 135 ELIFKWNKNRGNKEVQVSDELQIPQFILTEYKTTSEFANFTTGSYSRLTVLFRFERSIGF 194

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           +LIQ YIP+ LIV++SW++FW+N  +TPAR+ LG               A+LPK+SYVKS
Sbjct: 195 FLIQTYIPAYLIVMLSWIAFWINHTSTPARIGLGITTVLTMTTLTNSARASLPKVSYVKS 254

Query: 121 IDVYLGTCFVMVFASLLEYATVGY 144
           I+ +L  CF+ VF SL+EY  V Y
Sbjct: 255 IEWFLIMCFLYVFMSLVEYGCVSY 278


>UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit
           beta precursor (GABA(A) receptor subunit beta); n=3;
           Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit
           beta precursor (GABA(A) receptor subunit beta) -
           Caenorhabditis elegans
          Length = 550

 Score =  136 bits (329), Expect = 6e-31
 Identities = 65/142 (45%), Positives = 86/142 (60%), Gaps = 1/142 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++  KWN  P +V    +  +PQF + G       +S  TG+Y RL+   Q  RS+GY++
Sbjct: 207 EVLMKWNY-PLAVHGVEQADVPQFTITGFHTEDSIVSTATGSYQRLSLVFQLRRSVGYFI 265

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
            Q Y+P  LIV++SWVSFW+N  AT ARV+LG                +LP+ISYVKSID
Sbjct: 266 FQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRQSLPRISYVKSID 325

Query: 123 VYLGTCFVMVFASLLEYATVGY 144
           +YL  CFV VFA+LLEYA V Y
Sbjct: 326 IYLVMCFVFVFAALLEYAAVNY 347


>UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22;
           Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens
           (Human)
          Length = 512

 Score =  134 bits (325), Expect = 2e-30
 Identities = 65/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI + W    N+V   +++ LPQF ++ ++    ++  +TG+Y RL+   +  R++GY++
Sbjct: 187 DIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI 246

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG                 LPKI YVK+ID
Sbjct: 247 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306

Query: 123 VYLGTCFVMVFASLLEYATVGYM-AKRIQMRKQRFTAVQKMAVEKKIQID 171
           +YL  CFV VF +LLEYA V Y+   R   R+++       A  +K+++D
Sbjct: 307 MYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLD 356


>UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3
           precursor; n=128; Euteleostomi|Rep: Glycine receptor
           subunit alpha-3 precursor - Homo sapiens (Human)
          Length = 464

 Score =  134 bits (323), Expect = 3e-30
 Identities = 68/172 (39%), Positives = 105/172 (61%), Gaps = 8/172 (4%)

Query: 1   MRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLACEIQFVRSM 58
           M D+ ++W +E P  V V+  ++LPQF +   +  R       TG ++ +       R M
Sbjct: 196 MNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQM 253

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
           GYYLIQ+YIPS LIVI+SWVSFW+N +A PARV+LG               A+LPK+SYV
Sbjct: 254 GYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYV 313

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKR----IQMRKQRFTAVQKMAVEK 166
           K+ID+++  C + VF++LLEYA V +++++    ++ R++R    +  A+EK
Sbjct: 314 KAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEK 365


>UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subunit
           beta-like precursor (GABA(A) receptor); n=11;
           Protostomia|Rep: Gamma-aminobutyric acid receptor
           subunit beta-like precursor (GABA(A) receptor) -
           Drosophila melanogaster (Fruit fly)
          Length = 496

 Score =  133 bits (321), Expect = 5e-30
 Identities = 63/142 (44%), Positives = 86/142 (60%), Gaps = 2/142 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+   W   P  V    +  LPQF ++G+     +  L TG Y RL+   +  R++GY++
Sbjct: 203 DVVMYWK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFV 260

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
            Q Y+PS LIV++SWVSFW+N  AT ARV+LG               ++LP+ISYVK+ID
Sbjct: 261 FQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAID 320

Query: 123 VYLGTCFVMVFASLLEYATVGY 144
           +YL  CFV VFA+LLEYA V Y
Sbjct: 321 IYLVMCFVFVFAALLEYAAVNY 342


>UniRef50_O17547 Cluster: GluClalpha2A protein; n=66;
           Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis
           elegans
          Length = 657

 Score =  132 bits (318), Expect = 1e-29
 Identities = 64/161 (39%), Positives = 90/161 (55%), Gaps = 1/161 (0%)

Query: 2   RDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +DI Y W E  P  +      SLP F++             TG+YS L   IQ  R   Y
Sbjct: 409 KDIEYVWKEETPVQLKAGLSSSLPSFQLTNTSTTYCTSKTNTGSYSCLRTIIQLRRQFSY 468

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YL+Q+YIPS ++VI+SWVSFW++R A PARV+LG              NA LP ++Y+K+
Sbjct: 469 YLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKA 528

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161
           IDV++G C   +F +LLE+A V Y+A +    K+  T  +K
Sbjct: 529 IDVWIGACMTFIFCALLEFAWVTYIANKQDANKRARTEREK 569


>UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome
           shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
           SCAF14781, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 525

 Score =  131 bits (317), Expect = 2e-29
 Identities = 63/149 (42%), Positives = 94/149 (63%), Gaps = 2/149 (1%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRSMG 59
           M D+ ++W E   +V VS  ++LPQF +   ++         TG ++ +  +    R MG
Sbjct: 270 MNDLIFEWLEN-GAVQVSDGLTLPQFIMRDEKELGYCTKHYNTGKFTCIEVKFHLERQMG 328

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           YYLIQ+YIPS LIVI+SWVSFW+N +A PARV+LG               A+LPK+SYVK
Sbjct: 329 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 388

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKR 148
           +ID+++  C + VFA+LLEYA V +++++
Sbjct: 389 AIDIWMAVCLLFVFAALLEYAGVNFVSRQ 417


>UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio
           rerio|Rep: Glycine receptor, alpha 4b - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 536

 Score =  130 bits (315), Expect = 3e-29
 Identities = 67/169 (39%), Positives = 102/169 (60%), Gaps = 7/169 (4%)

Query: 1   MRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRSM 58
           M D+ ++W +EGP  V V+ ++ LPQF +   +          TG ++ +  +    R M
Sbjct: 240 MNDLIFQWLDEGP--VQVADDLMLPQFVLKEEKDLGYCTKHYNTGKFTCIEVKFHLERQM 297

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
           GYYLIQ+YIPS L VI+SWVSFW+N +A PARV LG               A+LPK+SYV
Sbjct: 298 GYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYV 357

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167
           K+ID+++  C + VFA+LLEYA V +++++    K+ F   +K+  E++
Sbjct: 358 KAIDIWMAVCLLFVFAALLEYAAVNFVSRQY---KEFFRLRRKLRQEQR 403


>UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 319

 Score =  129 bits (312), Expect = 6e-29
 Identities = 62/145 (42%), Positives = 84/145 (57%), Gaps = 3/145 (2%)

Query: 3   DIRYKWNE---GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMG 59
           D+ Y WNE     +++ +  ++ LPQF+VLG  + A       GN+S L    +  R +G
Sbjct: 175 DVLYVWNERLDNTSAIYIHDDLELPQFEVLGVSRSAKMNKYNIGNHSSLVANFRMKRRIG 234

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           Y+LI  YIPS +IVIISW+SFW++    PARV+LG               A LPK+SYVK
Sbjct: 235 YFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTMTTLISSARANLPKVSYVK 294

Query: 120 SIDVYLGTCFVMVFASLLEYATVGY 144
           +ID YL  C + VF S+LEY  V Y
Sbjct: 295 AIDWYLLLCLIFVFGSILEYTCVTY 319


>UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to
           gamma-aminobutyric acid A receptor beta 2S chain
           precursor - chicken; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric
           acid A receptor beta 2S chain precursor - chicken -
           Strongylocentrotus purpuratus
          Length = 418

 Score =  128 bits (309), Expect = 1e-28
 Identities = 57/142 (40%), Positives = 88/142 (61%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ + W  G +S+   + + + QF +  ++      + +TG+Y RLA   +  R++G++ 
Sbjct: 110 DVNFVWQYGDDSLEGVNNIEMAQFTLSDYKLIVKMQNFSTGSYPRLALTFRIKRNVGFFF 169

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q Y+PS L+V++SWVSFW+N  AT ARVSLG                +LP+ISYVKSID
Sbjct: 170 LQTYLPSILLVMLSWVSFWINHEATSARVSLGITTVLTMTTISTAVRQSLPRISYVKSID 229

Query: 123 VYLGTCFVMVFASLLEYATVGY 144
           +Y+ TC+  VFA+L+EYA V Y
Sbjct: 230 IYVITCYSFVFAALVEYAIVNY 251


>UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to
           glutamate-gated chloride channel; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to glutamate-gated
           chloride channel - Nasonia vitripennis
          Length = 510

 Score =  127 bits (307), Expect = 3e-28
 Identities = 65/160 (40%), Positives = 89/160 (55%), Gaps = 1/160 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ + W EG + V V   + LP+F +             TG YS L  ++ F R   YYL
Sbjct: 191 DLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYL 249

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQIYIP  ++VI+SWVSFWL+++A PARVSLG              NA+LP +SY K+ID
Sbjct: 250 IQIYIPCCMLVIVSWVSFWLDQSAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAID 309

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162
           V+ G C   VF +LLE+A V Y ++    R+      Q+M
Sbjct: 310 VWTGVCLTFVFGALLEFALVNYASRSDIHRENMKKKYQEM 349


>UniRef50_Q94900 Cluster: Glutamate-gated chloride channel
           precursor; n=21; Pancrustacea|Rep: Glutamate-gated
           chloride channel precursor - Drosophila melanogaster
           (Fruit fly)
          Length = 456

 Score =  126 bits (305), Expect = 4e-28
 Identities = 62/145 (42%), Positives = 83/145 (57%), Gaps = 1/145 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ + W EG + V V   + LP+F +             TG YS L  ++ F R   YYL
Sbjct: 190 DLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYL 248

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQIYIP  ++VI+SWVSFWL++ A PARVSLG              NA+LP +SY K+ID
Sbjct: 249 IQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAID 308

Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147
           V+ G C   VF +LLE+A V Y ++
Sbjct: 309 VWTGVCLTFVFGALLEFALVNYASR 333


>UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subunit
           rho-2 precursor (GABA(A) receptor subunit rho-2); n=99;
           Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit rho-2 precursor (GABA(A) receptor subunit rho-2)
           - Homo sapiens (Human)
          Length = 465

 Score =  126 bits (305), Expect = 4e-28
 Identities = 61/154 (39%), Positives = 90/154 (58%), Gaps = 2/154 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           D+   W  G  S+    ++SL QF +   H    +    +TG Y+RL       R + ++
Sbjct: 205 DLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFF 264

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           L+Q Y P+ L+V++SWVSFW++R A PARVSLG              NA++P++SYVK++
Sbjct: 265 LLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAV 324

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           D+YL   FV VF S+LEYA V Y+   +Q RK+R
Sbjct: 325 DIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKER 357


>UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated
           chloride-ion channel/receptor, zeta subunit precursor;
           n=1; Lymnaea stagnalis|Rep: Gamma-aminobutyric
           acid-grated chloride-ion channel/receptor, zeta subunit
           precursor - Lymnaea stagnalis (Great pond snail)
          Length = 437

 Score =  125 bits (301), Expect = 1e-27
 Identities = 60/142 (42%), Positives = 86/142 (60%), Gaps = 2/142 (1%)

Query: 9   NEGPNSVGVSSEVSLPQFKVLGHRQRAME--ISLTTGNYSRLACEIQFVRSMGYYLIQIY 66
           N    ++ V SEV LPQF+V                GN+S +  E    R++G+Y++Q+Y
Sbjct: 210 NPDGKAIVVDSEVLLPQFEVKSVIPSFCNRRYHQKAGNHSCIQAEFHLARNIGFYIVQMY 269

Query: 67  IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126
           IPS LIV++SW+SFWL  N+ P RVSLG              NAALP++SY K+IDV++ 
Sbjct: 270 IPSMLIVMLSWISFWLTVNSVPGRVSLGLLTVLTMTTQSSSVNAALPRVSYTKAIDVWMS 329

Query: 127 TCFVMVFASLLEYATVGYMAKR 148
           TC V VFA+LLE+A V  ++++
Sbjct: 330 TCLVFVFAALLEFAVVNVLSRK 351


>UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 469

 Score =  125 bits (301), Expect = 1e-27
 Identities = 65/167 (38%), Positives = 96/167 (57%), Gaps = 3/167 (1%)

Query: 4   IRYKWN--EGPNSVGVSSEVSL-PQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           I YKW   EG     V  +V L PQF +      +       GN+S +     F R+  +
Sbjct: 202 IMYKWEKGEGDGMSFVPRDVKLLPQFNLTKLELSSRNTQYVIGNWSGVMATFTFERTYSF 261

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           Y+I IY PS LIV+ISW+SF L R+ +PARV+LG              N A+PK++YVK+
Sbjct: 262 YVIHIYGPSALIVLISWISFLLPRDQSPARVTLGVTSVLTEVTILTMSNNAMPKVNYVKA 321

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKK 167
           +D YL  CF+ VFASL+EY+ +  +A R   R+++  A +++A+EK+
Sbjct: 322 VDKYLIACFLFVFASLMEYSLILVLANRTMRREKQKRAAKRLAMEKE 368


>UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3;
           Chromadorea|Rep: GBR-2A protein precursor - Haemonchus
           contortus (Barber pole worm)
          Length = 421

 Score =  124 bits (300), Expect = 2e-27
 Identities = 60/155 (38%), Positives = 88/155 (56%), Gaps = 1/155 (0%)

Query: 2   RDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +DI+Y+W E  P         SLP F++     +       TG YS L  ++   R   Y
Sbjct: 204 QDIKYEWKEQNPVQQKDGLRQSLPSFELQDVVTKYCTSKTNTGEYSCLRTQMVLRREFSY 263

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YL+Q+YIPS ++VI+SWVSFWL++++ PARV+LG              NA +P +SY K+
Sbjct: 264 YLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINANVPPVSYTKA 323

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           IDV++G C   +F +LLE+A V Y A++     QR
Sbjct: 324 IDVWIGVCLAFIFGALLEFAWVNYAARKDMSCGQR 358


>UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subunit
           beta precursor; n=8; Chromadorea|Rep: Glutamate-gated
           chloride channel subunit beta precursor - Caenorhabditis
           elegans
          Length = 434

 Score =  120 bits (288), Expect = 5e-26
 Identities = 64/163 (39%), Positives = 88/163 (53%), Gaps = 2/163 (1%)

Query: 1   MRDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLT-TGNYSRLACEIQFVRSM 58
           M DI Y+W+   P  +       LP F +  +   A   S T TG+Y  L  ++ F R  
Sbjct: 186 MNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCTSHTNTGSYGCLRMQLLFKRQF 245

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
            YYL+Q+Y P+ +IVI+SWVSFW++ ++T  RV+LG              NA LP +SYV
Sbjct: 246 SYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYV 305

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161
           K +DV+LG C   VF +LLEYA V Y     Q  + R  A +K
Sbjct: 306 KVVDVWLGACQTFVFGALLEYAFVSYQDSVRQNDRSREKAARK 348


>UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 447

 Score =  118 bits (284), Expect = 2e-25
 Identities = 55/148 (37%), Positives = 85/148 (57%), Gaps = 2/148 (1%)

Query: 3   DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           ++ YKW +GP  SV V+ E S L Q+ ++GH     +IS + G Y+ +       R +GY
Sbjct: 194 EVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTEDISTSRGQYTVMMAHFYLKRKIGY 253

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           ++IQ Y+P  + VI+S VSFWLNR + PAR   G                +LPK++Y  +
Sbjct: 254 FVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 313

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148
           +D ++  C+  VF++L+E+ATV Y  KR
Sbjct: 314 MDWFIAVCYAFVFSALIEFATVNYFTKR 341


>UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protein
           4; n=2; Caenorhabditis|Rep: Glutamate-gated chloride
           channel protein 4 - Caenorhabditis elegans
          Length = 500

 Score =  118 bits (283), Expect = 2e-25
 Identities = 55/169 (32%), Positives = 90/169 (53%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI Y W+     +   +  +LP F++   +  +      TG YS L  EI+  R   ++L
Sbjct: 209 DIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSKTNTGTYSCLKVEIRLNRVFSFFL 268

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q+YIPS ++V ++WVS+W++  +T ARV L               N+ LP +SY KSID
Sbjct: 269 LQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTSHAINSNLPPVSYAKSID 328

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQID 171
           +++G C V +F SL+EYA V Y+    + R+ +  A  +  +   I+ D
Sbjct: 329 IWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKKAACNRSRLSNVIEND 377


>UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12;
           Endopterygota|Rep: CG14723-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 426

 Score =  117 bits (281), Expect = 4e-25
 Identities = 56/142 (39%), Positives = 82/142 (57%), Gaps = 1/142 (0%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           + D+ + WN     V V++E+ LPQ  +  +      I  +TGN++ LA      R +GY
Sbjct: 207 VEDLVFIWNMTDPLV-VNTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGY 265

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           +L   YIPS LIV++SW+SFW+   A PARV+LG                +LP +SYVK+
Sbjct: 266 HLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKA 325

Query: 121 IDVYLGTCFVMVFASLLEYATV 142
           IDV++ +C V VF SL+E+A V
Sbjct: 326 IDVWMSSCSVFVFLSLMEFAVV 347


>UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 373

 Score =  116 bits (278), Expect = 8e-25
 Identities = 57/147 (38%), Positives = 88/147 (59%), Gaps = 4/147 (2%)

Query: 1   MRDIRYKWNEGPNS--VGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEIQFVRS 57
           + D+ YKW  G +   + V  +++L +F  L   Q   +IS   TG++S +  E    R 
Sbjct: 110 INDVVYKWRLGRSDEDIKVKQDLALTKF-TLWKIQTFTKISHYVTGSFSGIVAEFTMTRR 168

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
             YY+IQI++P  +IV +SW+SFW++ ++TPAR++LG               ++LPK+ Y
Sbjct: 169 ALYYVIQIFLPCAMIVFLSWISFWIDSHSTPARIALGITTVLSMTTLLFGVQSSLPKVPY 228

Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGY 144
           VKS+DVY+   F +VFASL+EYA V Y
Sbjct: 229 VKSLDVYMFVSFTLVFASLIEYACVHY 255


>UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit
           theta precursor (GABA(A) receptor subunit theta); n=18;
           Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit
           theta precursor (GABA(A) receptor subunit theta) - Homo
           sapiens (Human)
          Length = 632

 Score =  116 bits (278), Expect = 8e-25
 Identities = 52/145 (35%), Positives = 82/145 (56%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           + DI   W++  N++ ++ E+ +PQF  LG    + E+   TG+Y RL  + Q  R +  
Sbjct: 208 VEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNS 267

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YL+Q+Y P+ L  I SW+SFW+N +++ ARV++G                 LP IS +K+
Sbjct: 268 YLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKA 327

Query: 121 IDVYLGTCFVMVFASLLEYATVGYM 145
           ID+Y+  C   VF SLLEY  + Y+
Sbjct: 328 IDIYILVCLFFVFLSLLEYVYINYL 352


>UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit
           gamma-3 precursor (GABA(A) receptor subunit gamma-3);
           n=106; Euteleostomi|Rep: Gamma-aminobutyric acid
           receptor subunit gamma-3 precursor (GABA(A) receptor
           subunit gamma-3) - Homo sapiens (Human)
          Length = 467

 Score =  115 bits (277), Expect = 1e-24
 Identities = 54/141 (38%), Positives = 84/141 (59%), Gaps = 4/141 (2%)

Query: 6   YKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           Y+W +  NSV  + + S  L QF  +G R     ++ + G+Y  +    +  R MGY+ I
Sbjct: 201 YRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTI 258

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
           Q YIP  L V++SWVSFW+ ++ATPAR +LG                +LP++SYV ++D+
Sbjct: 259 QTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDL 318

Query: 124 YLGTCFVMVFASLLEYATVGY 144
           ++  CF+ VFA+L+EYAT+ Y
Sbjct: 319 FVTVCFLFVFAALMEYATLNY 339


>UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated
           chloride channel; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to GABA-gated
           chloride channel - Strongylocentrotus purpuratus
          Length = 530

 Score =  113 bits (272), Expect = 4e-24
 Identities = 53/125 (42%), Positives = 77/125 (61%), Gaps = 3/125 (2%)

Query: 3   DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           D+++KW E GP  V V  ++SLPQFK L    R+       GNY+ ++ +    R + YY
Sbjct: 199 DVKFKWLENGP--VYVDPKISLPQFKFLDSSVRSRIAEYFVGNYTVVSADFYLGRDITYY 256

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           ++Q YIPS +I  +SW+SFW+NRNA PARV+LG                +LPK+SY+K+I
Sbjct: 257 VVQTYIPSSMITCLSWLSFWINRNAVPARVALGITTVLTMTTLVGNAGNSLPKLSYIKAI 316

Query: 122 DVYLG 126
           D++LG
Sbjct: 317 DLFLG 321


>UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole
           genome shotgun sequence; n=2; Euteleostomi|Rep:
           Chromosome undetermined SCAF14659, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 481

 Score =  113 bits (271), Expect = 6e-24
 Identities = 58/168 (34%), Positives = 94/168 (55%), Gaps = 2/168 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           DI Y W+E    V    ++ L QF +  +R    M    + G + RL+   Q  R+ G Y
Sbjct: 212 DIVYHWSESQQHVHGLDKLELSQFTITDYRFDTEMMNFKSAGRFPRLSLCFQLRRNRGVY 271

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           +IQ Y+PS L+V +SWVSFW++++A PARV+LG               ++LP+ S +K++
Sbjct: 272 IIQSYMPSILLVAMSWVSFWISQSAVPARVTLGITTVLTMTTLMVSARSSLPRASAIKAL 331

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQ 169
           DVY   C+V VFA+L+EYA   Y A   +++++      K++ E  ++
Sbjct: 332 DVYFWICYVFVFAALIEYAFAHYNAD-YRLKEKAKVKASKLSSESIVK 378


>UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 538

 Score =  112 bits (269), Expect = 1e-23
 Identities = 52/149 (34%), Positives = 82/149 (55%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           +R  W      V    +V LP F +              G + +L  ++ F RS G+Y++
Sbjct: 243 VRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRRSYGFYIL 302

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
           QIY+P+  +V+ISW+SFWL+R + PARV+LG              + +LPK+SYVK +D+
Sbjct: 303 QIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYVKGLDL 362

Query: 124 YLGTCFVMVFASLLEYATVGYMAKRIQMR 152
           ++  C V +F S++E A VG + +R Q R
Sbjct: 363 FMFGCIVYIFLSIVELAVVGSLEQRKQQR 391


>UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1;
           Aplysia californica|Rep: GABA A receptor alpha subunit -
           Aplysia californica (California sea hare)
          Length = 448

 Score =  111 bits (268), Expect = 1e-23
 Identities = 52/146 (35%), Positives = 81/146 (55%), Gaps = 1/146 (0%)

Query: 3   DIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           D+ YKW  G   S+ ++ ++ L QF ++G+        +    +S L    Q  R  GY+
Sbjct: 185 DVIYKWRYGLQGSIELAPDLRLSQFDLVGYPLTNYTGLVKGAVHSVLCVTFQLSRHTGYF 244

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           LI +Y+P  L+V++SW SFW+NR AT  R++LG               + LPK+SY+ ++
Sbjct: 245 LINLYLPCCLLVVLSWASFWINREATADRIALGSTTVLTMTILGIENKSQLPKVSYITAL 304

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAK 147
           DVY+  CFV V A+ +E+A V Y  K
Sbjct: 305 DVYVALCFVFVIATTIEFAVVHYFTK 330


>UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit
           pi precursor (GABA(A) receptor subunit pi); n=19;
           Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit pi precursor (GABA(A) receptor subunit pi) -
           Homo sapiens (Human)
          Length = 440

 Score =  110 bits (265), Expect = 3e-23
 Identities = 51/156 (32%), Positives = 84/156 (53%), Gaps = 1/156 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ + W  G +SV     + L Q+ +  +          TGNY+RL  + +  R++ Y++
Sbjct: 187 DVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRRNVLYFI 246

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS-YVKSI 121
           ++ Y+PS  +V++SWVSFW++ ++ PAR  +G                +LP  + ++K+I
Sbjct: 247 LETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAI 306

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFT 157
           DVYLG CF  VF +LLEYA   Y + +    K R T
Sbjct: 307 DVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGT 342


>UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 304

 Score =  110 bits (264), Expect = 4e-23
 Identities = 56/142 (39%), Positives = 76/142 (53%), Gaps = 2/142 (1%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +R + Y+W   P    +  E+S  QF +              G YS L     F R +G+
Sbjct: 151 VRHLLYRWKNSPGIKVLDGEMS--QFYMTRITTSLRNEIYVAGEYSVLKASFTFQRRVGF 208

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           YLIQIYIP   IV ++W+S W++R ATPARVSL               NA++P++SYVKS
Sbjct: 209 YLIQIYIPCMAIVFVAWMSLWVDRRATPARVSLCITTLLTIATIWGNVNASMPRVSYVKS 268

Query: 121 IDVYLGTCFVMVFASLLEYATV 142
           ID+YL T F  V  +LLEY  +
Sbjct: 269 IDIYLMTSFTFVLGTLLEYIVI 290


>UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit
           delta precursor (GABA(A) receptor subunit delta); n=27;
           Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit delta precursor (GABA(A) receptor subunit delta)
           - Homo sapiens (Human)
          Length = 452

 Score =  110 bits (264), Expect = 4e-23
 Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 1/154 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNYSRLACEIQFVRSMGYY 61
           DI Y W+E    +    ++ L QF +  +R     ++  + G + RL+      R+ G Y
Sbjct: 191 DIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFHLRRNRGVY 250

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           +IQ Y+PS L+V +SWVSFW+++ A PARVSLG               ++LP+ S +K++
Sbjct: 251 IIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKAL 310

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           DVY   C+V VFA+L+EYA   + A   + +K +
Sbjct: 311 DVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK 344


>UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 291

 Score =  109 bits (263), Expect = 6e-23
 Identities = 48/139 (34%), Positives = 80/139 (57%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           +D+ Y+W + P ++  SS++ +  + ++     +      TG Y+ L  +  F R + +Y
Sbjct: 153 KDLVYEWMKNPPALEFSSQLRMAHYDLIEWSTESKLDEFVTGKYASLTAKFVFKRRVRFY 212

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           ++  +IP+  IVI+SWV FW++  + PARVSLG               + LP++ Y+K+I
Sbjct: 213 ILSAFIPAAFIVILSWVGFWIDERSVPARVSLGITTVLAITTLIFGVQSTLPRVGYIKAI 272

Query: 122 DVYLGTCFVMVFASLLEYA 140
           DVYL   F+ VFASL+EYA
Sbjct: 273 DVYLLGNFLFVFASLVEYA 291


>UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit
           alpha-4 precursor (GABA(A) receptor subunit alpha-4);
           n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit alpha-4 precursor (GABA(A) receptor subunit
           alpha-4) - Homo sapiens (Human)
          Length = 554

 Score =  109 bits (263), Expect = 6e-23
 Identities = 56/152 (36%), Positives = 81/152 (53%), Gaps = 3/152 (1%)

Query: 6   YKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           Y W +GP  SV V  E S L Q+ ++G    +  I   TG Y  +       R MGY++I
Sbjct: 202 YTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMI 261

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
           Q YIP  + VI+S VSFW+N+ + PAR   G                +LPK+SY+ ++D 
Sbjct: 262 QTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYLTAMDW 321

Query: 124 YLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           ++  CF  VF++L+E+A V Y    IQM K +
Sbjct: 322 FIAVCFAFVFSALIEFAAVNYFT-NIQMEKAK 352


>UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit
           alpha-3 precursor (GABA(A) receptor subunit alpha-3);
           n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit alpha-3 precursor (GABA(A) receptor subunit
           alpha-3) - Homo sapiens (Human)
          Length = 492

 Score =  109 bits (263), Expect = 6e-23
 Identities = 54/148 (36%), Positives = 81/148 (54%), Gaps = 2/148 (1%)

Query: 3   DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           ++ Y W  G N SV V+ + S L Q+ +LGH      I  +TG Y  +       R +GY
Sbjct: 218 EVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGY 277

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           ++IQ Y+P  + VI+S VSFWLNR + PAR   G                +LPK++Y  +
Sbjct: 278 FVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 337

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148
           +D ++  C+  VF++L+E+ATV Y  KR
Sbjct: 338 MDWFIAVCYAFVFSALIEFATVNYFTKR 365


>UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit
           alpha-5 precursor (GABA(A) receptor subunit alpha-5);
           n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
           subunit alpha-5 precursor (GABA(A) receptor subunit
           alpha-5) - Homo sapiens (Human)
          Length = 462

 Score =  109 bits (262), Expect = 7e-23
 Identities = 52/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%)

Query: 3   DIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           ++ Y W  G   SV V+ + S L Q+ ++G       IS +TG Y+ +       R +GY
Sbjct: 200 EVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGY 259

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           ++IQ Y+P  + VI+S VSFWLNR + PAR   G                +LPK++Y  +
Sbjct: 260 FVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 319

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKR 148
           +D ++  C+  VF++L+E+ATV Y  KR
Sbjct: 320 MDWFIAVCYAFVFSALIEFATVNYFTKR 347


>UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 564

 Score =  109 bits (261), Expect = 1e-22
 Identities = 60/156 (38%), Positives = 89/156 (57%), Gaps = 11/156 (7%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVL--------GHRQRAM-EISLTTGNYSRLACEI 52
           + +   W +  N V  + E+ LP+F++         G  Q A+ E S  + ++S L+  +
Sbjct: 177 KQVNVTWFD-KNPVRFNEEIGLPEFQIEHVSNAYCNGSYQYALTENSYKSDDFSCLSGNL 235

Query: 53  QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAAL 112
              RS+GY L+Q YIP+GLIV+ISWVSFW++R A PARV+L                  L
Sbjct: 236 FLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVPARVTLSFTTLVSLTTLGNGLRFGL 295

Query: 113 PKISYVKSIDVYLGTCFVMVFASLLEYATV-GYMAK 147
           P++SY K+ID++ G C   VF +LLE+AT+  YM K
Sbjct: 296 PQVSYAKAIDLWYGACMFFVFCALLEFATINSYMRK 331


>UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated
           ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to GABA-gated ion channel - Nasonia vitripennis
          Length = 442

 Score =  108 bits (260), Expect = 1e-22
 Identities = 53/146 (36%), Positives = 78/146 (53%), Gaps = 1/146 (0%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           RD+ YKWN     V ++ ++ L QF ++G+       S  +  YS L       R MG +
Sbjct: 200 RDVIYKWNSA-RQVAIAHDMKLSQFDLVGNPTANATDSTLSQKYSMLLVSFHLKRHMGNF 258

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           LIQ+Y P  L+V++SWVSFWLNR AT  RVSLG                 LPK+ Y  ++
Sbjct: 259 LIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPTAL 318

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAK 147
           D ++   F  +FA+++++A V Y  K
Sbjct: 319 DFFVFLSFGFIFATIIQFAVVHYFTK 344


>UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 293

 Score =  108 bits (259), Expect = 2e-22
 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 3/143 (2%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNYSRLACEIQFVRSMG 59
           + DI Y+W    + + +  E++  +F++   R +R  +    TG Y+ L  +  F R + 
Sbjct: 153 INDIDYRWKAKEDLIILDGEMN--EFELKDSRGERKQKSRSCTGTYTHLVAKFVFRRRLA 210

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           Y  IQIY P+ LIV++SW+SFW++++A PARV+LG                ++PK+SY+K
Sbjct: 211 YSFIQIYSPTFLIVVLSWLSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIK 270

Query: 120 SIDVYLGTCFVMVFASLLEYATV 142
           +ID+YL   F+ VF +LLEY  V
Sbjct: 271 AIDLYLIVSFIFVFGTLLEYIAV 293


>UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 424

 Score =  107 bits (258), Expect = 2e-22
 Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 2/145 (1%)

Query: 3   DIRYKW-NEGPNSVGVSSEV-SLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +++Y+W N   N + V+ ++  +PQ+ +              GN+S L    +F R  GY
Sbjct: 156 NVQYQWENRSDNGIAVNKKIRDMPQYNLSDINVSRHFTMYVAGNWSGLTATFRFRRRSGY 215

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           ++I IY P  LIVI+SW+SF +   +T AR++LG              N ++PK+SYVK+
Sbjct: 216 FIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKA 275

Query: 121 IDVYLGTCFVMVFASLLEYATVGYM 145
           +D YL  CF+ VFA LLEY  V Y+
Sbjct: 276 VDWYLIGCFLFVFAVLLEYTFVLYI 300


>UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid
           A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep:
           PREDICTED: gamma-aminobutyric acid A receptor, alpha 6
           isoform 1 - Pan troglodytes
          Length = 478

 Score =  107 bits (257), Expect = 3e-22
 Identities = 55/155 (35%), Positives = 82/155 (52%), Gaps = 3/155 (1%)

Query: 3   DIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +I Y W +GP  SV V  E S L Q+ ++G    +  I   TG Y  +       R MGY
Sbjct: 208 EIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGY 267

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           ++IQIY P  + VI+S VSFW+N+ + PAR   G                +LPK+SY  +
Sbjct: 268 FMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATA 327

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           +D ++  CF  VF++L+E+A V Y    +Q +K +
Sbjct: 328 MDWFIAVCFAFVFSALIEFAAVNYFT-NLQTQKAK 361


>UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis
           mellifera|Rep: GABA-gated ion channel - Apis mellifera
           (Honeybee)
          Length = 463

 Score =  105 bits (253), Expect = 9e-22
 Identities = 53/148 (35%), Positives = 78/148 (52%), Gaps = 3/148 (2%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFVRSMG 59
           RD+ YKWN     V ++ ++ L QF ++ +       S T  +  YS L       R MG
Sbjct: 156 RDVIYKWNSA-RQVAIAEDMKLSQFDLVANPTANYSASTTLSHAEYSMLLVYFHLQRHMG 214

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
            +LIQ+Y P  L+V++SWVSFWLNR AT  RVSLG                 LPK+ Y  
Sbjct: 215 NFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPYPT 274

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAK 147
           ++D ++   F  +FA+++++A V Y  K
Sbjct: 275 ALDFFVFLSFAFIFATIIQFAVVHYFTK 302


>UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 291

 Score =  105 bits (252), Expect = 1e-21
 Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 1/139 (0%)

Query: 7   KWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65
           KW  G   SV  +  ++LPQ  VLG + R +     +GNYSRL+   +F R +  +L + 
Sbjct: 152 KWKFGETGSVTWAENINLPQMDVLGVKGREVVDVFASGNYSRLSLAFKFKRRISLFLTET 211

Query: 66  YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125
           Y+P  LIV +SWVSFW+N    PARV+L                 +LPK++Y K  D  L
Sbjct: 212 YVPLVLIVALSWVSFWINYKVAPARVALCITTVLTIITLSASVRTSLPKVTYTKYSDWIL 271

Query: 126 GTCFVMVFASLLEYATVGY 144
            T  V VF +L+EYA V Y
Sbjct: 272 ITGLVYVFGALVEYAVVNY 290


>UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 366

 Score =  105 bits (252), Expect = 1e-21
 Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 3/144 (2%)

Query: 1   MRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAM-EISLTTGNYSRLACEIQFVRSM 58
           + D+ Y WN  G   + + +   + QF +     + M   SL TG++  L    +F R  
Sbjct: 108 VEDVIYNWNNRGTTPIEIFAG-EMAQFDMTEMTMQTMITFSLLTGSFDSLRVSFRFKRRT 166

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
            Y+++Q Y+PS  IV +SW+ FW+N+NA PAR+SL               N++LP+ISY+
Sbjct: 167 SYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYL 226

Query: 119 KSIDVYLGTCFVMVFASLLEYATV 142
           K++D YL   F+ + AS++EY  V
Sbjct: 227 KAVDYYLIISFMFILASMVEYVLV 250


>UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 434

 Score =  104 bits (250), Expect = 2e-21
 Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 3/158 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+  +W E      V ++ +LP F++      ++  + T G + RL+  I F R  G+Y+
Sbjct: 208 DVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTEAYTAGMWHRLSVSIHFERLYGFYI 267

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q+Y+P+ + V ISW++FW++  A PAR++L                 +LPK SYVK+ID
Sbjct: 268 LQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMALTFQFGNIVKSLPKASYVKAID 327

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQ 160
           +++ +C   +F SL+E A V Y  K   M  QR   V+
Sbjct: 328 IWMFSCVGFIFFSLIELAIVAYNDK---MHDQRLREVR 362


>UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4
           precursor; n=2; Caenorhabditis|Rep: Glycine receptor
           subunit beta-type 4 precursor - Caenorhabditis elegans
          Length = 473

 Score =  104 bits (250), Expect = 2e-21
 Identities = 52/142 (36%), Positives = 75/142 (52%), Gaps = 1/142 (0%)

Query: 7   KWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIY 66
           +WN G N V V+  + +P   +   +         TG +S    E    R + +++IQ Y
Sbjct: 197 RWNGG-NPVEVNRGIRMPDMHLKHIKFYTKRDKYATGIWSSAVAEFHVDREITHHIIQSY 255

Query: 67  IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126
           IP+ LIVIISW SFWL+  A P RVSL                 ALP+ S VK+IDV++G
Sbjct: 256 IPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARMALPQASDVKAIDVWMG 315

Query: 127 TCFVMVFASLLEYATVGYMAKR 148
           TC   VF++++E+  V Y  +R
Sbjct: 316 TCMAFVFSAMIEFTVVNYCVRR 337


>UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protein
           1; n=6; Caenorhabditis|Rep: Expulsion defective
           (Defecation) protein 1 - Caenorhabditis elegans
          Length = 539

 Score =  103 bits (248), Expect = 4e-21
 Identities = 52/158 (32%), Positives = 83/158 (52%), Gaps = 3/158 (1%)

Query: 6   YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65
           YKW++G  +     ++ LP F +      +   S  TGNYSRL     F RS G+  +Q+
Sbjct: 261 YKWSKGARTALELKKIRLPDFTIQEAYVTSQMESYATGNYSRLYVCFVFSRSSGFCFLQL 320

Query: 66  YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125
            IPS  +VI SWVS W+    T                     N  +P++SY+K++D+YL
Sbjct: 321 IIPSTAVVITSWVSLWME---TETEFQDMISIILAITFLIFSYNEMMPRVSYIKAMDIYL 377

Query: 126 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMA 163
           G CF++VF SL++ A V YM ++I +      ++++M+
Sbjct: 378 GVCFMIVFLSLIKLALVKYMRQKIMLTSDSGNSLREMS 415


>UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3;
           Rhabditida|Rep: GABA A/glycine receptor subunit -
           Haemonchus contortus (Barber pole worm)
          Length = 472

 Score =  103 bits (248), Expect = 4e-21
 Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 6/155 (3%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS--LTTG-NYSRLACEIQFVRSMG 59
           D+ Y W +      + + +S  Q+K+LG  +     S     G N S L    +  R  G
Sbjct: 191 DVVYYWKDVELDAKMGNMLS--QYKILGLFKSEHNFSDHREIGRNISVLKVYFKLQRQQG 248

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           YY++QIY P  L+V++SWVSFW+N+ A+PARV+LG                 LPK+S+  
Sbjct: 249 YYVLQIYTPCTLLVVMSWVSFWINKEASPARVALGIMTVLSMSTLGFGLRTDLPKVSHST 308

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154
           ++D+Y+ +CF  VFA+++EY+ + Y A+ + +RKQ
Sbjct: 309 ALDIYILSCFGFVFAAMVEYSVINY-AQIVYIRKQ 342


>UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 303

 Score =  103 bits (248), Expect = 4e-21
 Identities = 48/148 (32%), Positives = 79/148 (53%), Gaps = 2/148 (1%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLP--QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58
           M+D+ YKW + P    + +   L   +F ++  +          GN+S L   I   R  
Sbjct: 155 MKDVVYKWLDDPKQKTIETAEGLDATEFSIVSLKTMENISVFNLGNFSSLTMRIYLDRRT 214

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
            YY+IQIYIP  +IV++SW+SFWL+  + PAR +LG               ++LP + Y+
Sbjct: 215 TYYVIQIYIPCSMIVMLSWISFWLDYKSVPARTALGITTVLAMTTLLFGIQSSLPGVPYI 274

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMA 146
           K++D +L   F  VF +L+E+A V +++
Sbjct: 275 KAVDQFLIVSFACVFVALIEFAVVNFIS 302


>UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 201

 Score =  103 bits (246), Expect = 6e-21
 Identities = 49/115 (42%), Positives = 67/115 (58%)

Query: 42  TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXX 101
           TGN+S L    +F R + YYL + YIP+ L V++SWVSFW++  ATPAR+SL        
Sbjct: 4   TGNFSALTVGFRFRREVYYYLFRFYIPASLTVVMSWVSFWISPLATPARISLTIITVLAM 63

Query: 102 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF 156
                  +   PK SY +S DVY+  CFV VF  L+EYA V Y+ +  +  K+ F
Sbjct: 64  AGFLIGDHPDFPKSSYARSFDVYMMMCFVFVFGCLVEYAAVHYLLRDDKYNKKVF 118


>UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 262

 Score =  102 bits (244), Expect = 1e-20
 Identities = 53/155 (34%), Positives = 85/155 (54%), Gaps = 8/155 (5%)

Query: 3   DIRYKWNEGP-----NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57
           D+   W   P     N+V +S  +++ QF +  +       +  TG ++ L       R 
Sbjct: 106 DLLLSWKADPGDKYKNAVIISDNLTMSQFALDEYHASKETFTYPTGTFTLLKLTFSIRRK 165

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
             YY++Q YIP+ LIVI+SWVSFW+ R++ PARV+LG               +++P++SY
Sbjct: 166 KFYYVVQTYIPTILIVILSWVSFWIPRSSPPARVALGITTVLALTTLIFGIQSSMPRVSY 225

Query: 118 VKSIDVYLGTCFVMVFASLLEYAT---VGYMAKRI 149
           VK+ID +L   F+ VF +L+EY +   + + AKRI
Sbjct: 226 VKAIDWFLMVSFLFVFCALIEYPSSTFIKFQAKRI 260


>UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop
           ligand-gated ion channel subunit; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to cys-loop
           ligand-gated ion channel subunit - Nasonia vitripennis
          Length = 513

 Score =  101 bits (243), Expect = 1e-20
 Identities = 49/157 (31%), Positives = 91/157 (57%), Gaps = 11/157 (7%)

Query: 1   MRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLACE 51
           ++D+   W+E P  + ++ E+ L +++++       E+S TT         GN+S ++  
Sbjct: 203 VQDMILNWDEAP--IVLADELHLTEYRLVEQWVNRSEVSYTTAQQHYGHFAGNFSSISIT 260

Query: 52  IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAA 111
            +  R MG++++  YIPS LIV+ISWVSFWL+ +A+P R+ LG                +
Sbjct: 261 FKLAREMGFFMMDYYIPSILIVVISWVSFWLHVDASPPRIVLGTNTILAFMTLASKVENS 320

Query: 112 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
           LPK+SY+K+ +++   C + +FA+++E+A V  + +R
Sbjct: 321 LPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTIYRR 357


>UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 382

 Score =  101 bits (243), Expect = 1e-20
 Identities = 51/133 (38%), Positives = 70/133 (52%)

Query: 39  SLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXX 98
           S   G +S L   ++  R++G++L+Q YIP+GLIV ISWVSFW++R A PARVSL     
Sbjct: 182 SSRVGEFSCLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDRRAVPARVSLSFTTL 241

Query: 99  XXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTA 158
                       ALP +SY K+ID + G C + +F  LLE+A V    +R          
Sbjct: 242 LTLSTQGNGIRYALPAVSYAKAIDYFYGVCMLFIFGVLLEFAAVNSYMRRANKYNHMAEK 301

Query: 159 VQKMAVEKKIQID 171
           +Q     K I  D
Sbjct: 302 IQSAYGGKPIIAD 314


>UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein acc-1 - Caenorhabditis elegans
          Length = 466

 Score =  101 bits (243), Expect = 1e-20
 Identities = 51/145 (35%), Positives = 81/145 (55%), Gaps = 1/145 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++R +WN+ P  V +   + LP FK++     A+E     G +  L     F R  G+Y+
Sbjct: 185 EVRMQWNQ-PYPVILLKRIELPDFKLVNFSVIAVEQMYPAGWWDELTVAFVFERRYGWYV 243

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q YIP+ + ++ISW+SF+L   A PAR  LG                 LP++SYVK+ID
Sbjct: 244 LQGYIPTMVTIVISWISFYLGPRAIPARTMLGVNSLLAMTFQFGNIIRNLPRVSYVKAID 303

Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147
           V++ +  + +F SLLE A VG+M++
Sbjct: 304 VWMLSGMLFIFLSLLELAVVGFMSR 328


>UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor;
           n=34; Euteleostomi|Rep: Glycine receptor subunit beta
           precursor - Homo sapiens (Human)
          Length = 497

 Score =  101 bits (242), Expect = 2e-20
 Identities = 57/165 (34%), Positives = 90/165 (54%), Gaps = 8/165 (4%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLACEIQFVRSMG 59
           D+R+ W  G + V +  +++LPQF +           +    TG Y+ +       R +G
Sbjct: 210 DLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVG 267

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           +Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG               A LPK+SYVK
Sbjct: 268 FYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVK 327

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFTAVQK 161
           ++DV+L  C +  FASL+EYA V  M    KR++  K R    ++
Sbjct: 328 ALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQ 372


>UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 270

 Score =   99 bits (238), Expect = 6e-20
 Identities = 43/136 (31%), Positives = 75/136 (55%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           +I  +W EG   V +S +++LP F ++G   + +     +G ++ L   I F R +GYYL
Sbjct: 135 EIVLRWEEGDTPVAISKDMNLPHFDIVGLETKQIYNVYKSGKFNSLEVHITFRRRLGYYL 194

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQ Y+P   +  +SW+ FW++ + T  R+++G              N  +PK+SY+K+ID
Sbjct: 195 IQTYLPCVFLCFLSWMPFWMDPSETGDRLAVGITAVLTIVFLAGAMNTNMPKVSYMKAID 254

Query: 123 VYLGTCFVMVFASLLE 138
            Y+  CF+ +  S +E
Sbjct: 255 WYVIACFLTMVLSFVE 270


>UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep:
           CG7411-PA - Drosophila melanogaster (Fruit fly)
          Length = 485

 Score = 99.5 bits (237), Expect = 8e-20
 Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 1/140 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ ++W+     V V   + LPQ  ++ +         +TGN++ L       R + YY+
Sbjct: 182 DLIFQWDPTTPLV-VDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYV 240

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
              YIP+ +IVI+SWVSFW+   A PARV+LG               ++LP +SY+K++D
Sbjct: 241 FNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVD 300

Query: 123 VYLGTCFVMVFASLLEYATV 142
            ++  C V VF +L+EY  +
Sbjct: 301 AFMSVCTVFVFMALMEYCLI 320


>UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 270

 Score = 99.5 bits (237), Expect = 8e-20
 Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 5/142 (3%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           D+ Y WN+     G     +L QF +LG       +  T+G YS L    +F R +  YL
Sbjct: 116 DLYYDWNDVSIYKG-----NLSQFDLLGLDSLRKSLVFTSGTYSSLVATFRFRRRIQNYL 170

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +  Y+P+ L V++SWVSF+++ N+ PAR +LG                + P +SYV S D
Sbjct: 171 LSFYVPTILTVMLSWVSFFISPNSAPARCALGIITVLAVGGFLTNQRKSFPTVSYVMSAD 230

Query: 123 VYLGTCFVMVFASLLEYATVGY 144
           +Y+  C+V VF +LLEYA V +
Sbjct: 231 LYILVCYVFVFCALLEYAVVHF 252


>UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 469

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 50/147 (34%), Positives = 80/147 (54%), Gaps = 1/147 (0%)

Query: 13  NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI-YIPSGL 71
           N V V  E+SL  F +  +R          G + RL  E +F R  G+Y++Q+ Y+P+ +
Sbjct: 190 NPVTVLPEISLADFDLSRYRTSRHTEVYKAGEWYRLTVEFEFTRKYGFYILQVLYVPTYI 249

Query: 72  IVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVM 131
            + ISW++F ++  A PAR+ LG                +LP +SYVK+ID+++ TC   
Sbjct: 250 SLFISWIAFCIDTKALPARIVLGVNSLMSLTFQFGNIIRSLPPVSYVKAIDLWMCTCVGF 309

Query: 132 VFASLLEYATVGYMAKRIQMRKQRFTA 158
           +FASLLE A V Y  K++ ++  +  A
Sbjct: 310 IFASLLELAFVAYQDKKLILKSGKSNA 336


>UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 457

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 50/155 (32%), Positives = 80/155 (51%), Gaps = 1/155 (0%)

Query: 2   RDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +++R +WNE     V V++++ LP F+++      +      G +  L  ++ F R   +
Sbjct: 207 QEVRMRWNEKSAEPVSVTNKIRLPDFELIKIESTRISAPYPAGMWDELHVKLVFERRYIW 266

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           Y +Q Y+P+ L + ISW+SF L   A PAR  LG                 LP++SYVK+
Sbjct: 267 YFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNALLAMIFQFGNIMRNLPRVSYVKA 326

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           IDV++      +F SLLE A VGY  K  +  K++
Sbjct: 327 IDVWMLVSMTFIFLSLLELAIVGYKTKNEEGSKKK 361


>UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subunit;
           n=2; Apis mellifera|Rep: Cys-loop ligand-gated ion
           channel subunit - Apis mellifera (Honeybee)
          Length = 469

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 49/155 (31%), Positives = 89/155 (57%), Gaps = 11/155 (7%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLACEIQ 53
           D+   W++ P  + ++ E+ L ++K++     + EI  TT         GN+S ++   +
Sbjct: 169 DMVLYWDQEP--IILADELHLTEYKLVEKWVNSSEIFYTTSQQYYGHFAGNFSSISITFK 226

Query: 54  FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALP 113
             R MG++++  YIPS LIV+ISWVSFWL+ +A+P R+ LG                +LP
Sbjct: 227 LAREMGFFMMDYYIPSILIVVISWVSFWLHMDASPPRIVLGTNTILTFMTLASKVENSLP 286

Query: 114 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
           K+SY+K+ +++   C + +FA+++E+A V  + +R
Sbjct: 287 KVSYIKASEIWFLGCTIFLFAAMVEFAFVNTIYRR 321


>UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 494

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 47/153 (30%), Positives = 85/153 (55%), Gaps = 3/153 (1%)

Query: 1   MRDIRYKWNEGPN--SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58
           M  +R  W+E  +  ++  + ++++P   +   R      +  TG +S +       R M
Sbjct: 183 MTVLRLLWSEKEDVPAIDRNPDITMPDMSLKHIRTGYCNGTYATGEWSCMTAIFYVEREM 242

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
            ++++Q Y+P+ LIV+ISW +FWL  ++ PARVSL                 ALP++SY+
Sbjct: 243 MHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSLSITTLLTISTQANAVKLALPEVSYM 302

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM 151
           K+IDV++G+C   VF  ++E+ T+ + AK ++M
Sbjct: 303 KAIDVWMGSCMAFVFGVMIEF-TICHYAKNLEM 334


>UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p
           - Drosophila melanogaster (Fruit fly)
          Length = 612

 Score = 97.1 bits (231), Expect = 4e-19
 Identities = 49/142 (34%), Positives = 72/142 (50%)

Query: 6   YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65
           Y+W    ++V     ++L QF ++    R        G++S L       R  GY+LIQ+
Sbjct: 263 YEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQV 322

Query: 66  YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125
           Y+P  LIV++SWVSFW++R AT  RVSL                  LPK+ Y  ++D +L
Sbjct: 323 YVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFL 382

Query: 126 GTCFVMVFASLLEYATVGYMAK 147
              F+   A+LLE+A V Y  K
Sbjct: 383 LMSFLYCIATLLEFAGVHYFTK 404


>UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 405

 Score = 97.1 bits (231), Expect = 4e-19
 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%)

Query: 3   DIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           D+ Y+W  G    V + SE  + QF +LG R    + + + G ++ L    +F R M +Y
Sbjct: 191 DVDYRWKGGETQGVEIVSE-EMAQFDLLGVRTDTKKSTNSKGAFASLKATFRFRRRMDFY 249

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           L  IY+P  ++V++SW +F++  +A PAR +L               N+ +PK+SY+KSI
Sbjct: 250 LSSIYVPEVILVVLSWTTFFITPSAVPARTALSITTILTTILLSSSVNSGMPKVSYMKSI 309

Query: 122 DVYLGTCFVMVFASLLEYATV 142
           D ++   F  +FA+L+EY  V
Sbjct: 310 DHFMLISFGFIFAALIEYIIV 330


>UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr)
           protein 2, isoform a; n=3; Caenorhabditis|Rep:
           Gaba/glycine receptor family (See gbr) protein 2,
           isoform a - Caenorhabditis elegans
          Length = 546

 Score = 95.9 bits (228), Expect = 1e-18
 Identities = 44/142 (30%), Positives = 77/142 (54%), Gaps = 1/142 (0%)

Query: 7   KWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIY 66
           KW E    +  +  +++    ++       + + +TG +S +  E    R + ++++Q Y
Sbjct: 187 KWKED-EPITRNPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSY 245

Query: 67  IPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 126
           +P+ LIV+ISW SFWL+  A PARVSL                 ALP++SY+K+IDV++G
Sbjct: 246 VPTTLIVVISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMALPEVSYMKAIDVWMG 305

Query: 127 TCFVMVFASLLEYATVGYMAKR 148
            C + VF  ++E+  V Y  ++
Sbjct: 306 ACMMFVFGVMIEFTIVNYAQRQ 327


>UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 303

 Score = 95.9 bits (228), Expect = 1e-18
 Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 3/154 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI Y+W +    V  + +  + QF +       +     TG++S L   ++  R +G+YL
Sbjct: 134 DIVYQWAD--ERVTWAHDQEIAQFVLEKIETENLTRRYITGDFSALGIRLRLNRRLGHYL 191

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLG-XXXXXXXXXXXXXXNAALPKISYVKSI 121
            ++Y+P+ LIV++SW+SF+L+R++ PARVSLG                 +LP +SYVK++
Sbjct: 192 TRVYVPAVLIVMLSWLSFYLDRHSAPARVSLGITTVLTMTTLLIGIGQGSLPVVSYVKAL 251

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           D YL   + MVF +  EYA + +  K   ++ +R
Sbjct: 252 DWYLFVSYCMVFGAFAEYAVINHRDKSYFLKLRR 285


>UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit;
           n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
           channel subunit - Apis mellifera (Honeybee)
          Length = 510

 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 47/127 (37%), Positives = 66/127 (51%)

Query: 21  VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSF 80
           ++L QF ++G   R +      G +S L       R  GY+LIQ+Y+P  LIV++SWVSF
Sbjct: 207 MALSQFDLMGSPYRNLTFVRREGEFSVLQVSFNLQRHTGYFLIQVYVPCVLIVVLSWVSF 266

Query: 81  WLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYA 140
           W++R AT  RV LG                 LPK+ Y  ++D +L   F    A+LLE+A
Sbjct: 267 WIHREATSDRVGLGITTVLTLSTISLDSRTDLPKVRYATALDWFLLMSFGYCIATLLEFA 326

Query: 141 TVGYMAK 147
            V Y  K
Sbjct: 327 GVHYFTK 333


>UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subunit;
           n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
           channel subunit - Apis mellifera (Honeybee)
          Length = 391

 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 51/159 (32%), Positives = 88/159 (55%), Gaps = 5/159 (3%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGH--RQRAMEISLT-TGNYSRLACEIQFVRSMGY 60
           +R +W  G  +V V+ E+ L Q+ +      +  ++  L  +GN+SRL    +F R +G+
Sbjct: 144 LRLRWGTG--AVTVNPELKLLQYDIGKPVVAEETVDYMLEKSGNFSRLVVFFRFERQIGH 201

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           +LIQ + PS L+V++SW SFWL  +A P RV+L                + +P ++YVK+
Sbjct: 202 HLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGLKSDIPPVAYVKA 261

Query: 121 IDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAV 159
           +DV++  C + VFA+L E+  V  +  R Q+     T++
Sbjct: 262 LDVWMAGCMMFVFAALGEFVVVKVLDLRSQLEYDLQTSI 300


>UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 299

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 48/138 (34%), Positives = 77/138 (55%), Gaps = 2/138 (1%)

Query: 2   RDIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGY 60
           +DI+Y+W    NS V V S  +L QF +    +         GN +R+     F R +GY
Sbjct: 163 QDIKYRWRPPMNSSVDVRSR-NLAQFALTSIIEVEYVEHYDLGNQNRMCVCFTFQRRLGY 221

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKS 120
           +LIQ+YIPS  +V++SW+ FW++++    R++LG              NA++P++SY K+
Sbjct: 222 FLIQVYIPSIFVVVLSWIVFWMDKDNMGDRMALGITTVLTIMFLLGAVNASMPRVSYPKA 281

Query: 121 IDVYLGTCFVMVFASLLE 138
           +D YL   F +VF  L+E
Sbjct: 282 LDWYLMVSFTLVFLVLIE 299


>UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 443

 Score = 93.5 bits (222), Expect = 5e-18
 Identities = 49/156 (31%), Positives = 79/156 (50%), Gaps = 1/156 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI ++WN  PN +    +  L QF + G+           GNY+ +    +  R +GYY+
Sbjct: 176 DIFFRWNN-PNKLSRVQKSDLAQFHLAGYDLITETGIYEEGNYTTVKVIFKMNRRVGYYI 234

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQ Y P  LIV++SW+ FW++      R++LG              NA++PK+SY K++D
Sbjct: 235 IQAYCPDVLIVVLSWIIFWMDVKDMGDRMALGITTILTIMFLLGAVNASMPKVSYPKALD 294

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTA 158
            YL   F  VF +L+E   V  +  + +  K + T+
Sbjct: 295 WYLMVSFAFVFLTLIESMIVFLLTPQGESEKPKKTS 330


>UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG02331 - Caenorhabditis
           briggsae
          Length = 472

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 5/157 (3%)

Query: 3   DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFV----RS 57
           ++R  W +  P ++    +  LP F+             T G + +L     F     R 
Sbjct: 222 EVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFSFFFRFKRL 281

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
            GYY++Q+Y+P+ L V ISW++FW++  A PAR++LG                 LP++S+
Sbjct: 282 YGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFGNIVKNLPRVSF 341

Query: 118 VKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154
           VK+ID++   C   +F SL+E A VG++ K  +++++
Sbjct: 342 VKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRR 378


>UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 47/152 (30%), Positives = 76/152 (50%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           +D+ Y W     S     +  + QF ++  ++        +  +S L   + F R   YY
Sbjct: 152 KDLNYTWRSKVGSDIAIYDKEMAQFDIIAAKRFLKHPVYHSPMFSGLTATMSFRRRSLYY 211

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           + Q+YIP   +VI+SW++FW++      RV LG              NA +P++SY+KSI
Sbjct: 212 IFQMYIPCTCVVILSWIAFWIDPKEGSERVGLGISAVLTISYMRGSMNAGMPRVSYLKSI 271

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRK 153
           D +L   FV VF SL+EY  V   A++ + +K
Sbjct: 272 DYFLLISFVFVFMSLIEYVLVLKDARKERRKK 303


>UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subunit
           epsilon precursor (GABA(A) receptor subunit epsilon);
           n=30; Eutheria|Rep: Gamma-aminobutyric acid receptor
           subunit epsilon precursor (GABA(A) receptor subunit
           epsilon) - Homo sapiens (Human)
          Length = 506

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 41/140 (29%), Positives = 65/140 (46%)

Query: 6   YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 65
           YKW      +   +   L QF   G   +   I+   G++  +       R  GY   Q 
Sbjct: 225 YKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQN 284

Query: 66  YIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 125
           Y+PS +  ++SWVSFW+   + PAR SLG                  P++SY+ ++D Y+
Sbjct: 285 YVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYI 344

Query: 126 GTCFVMVFASLLEYATVGYM 145
             CFV  F +LLE+A + ++
Sbjct: 345 AICFVFCFCALLEFAVLNFL 364


>UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory
           glycine receptor; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to inhibitory glycine
           receptor - Strongylocentrotus purpuratus
          Length = 431

 Score = 92.7 bits (220), Expect = 9e-18
 Identities = 46/141 (32%), Positives = 76/141 (53%)

Query: 18  SSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISW 77
           S  + LPQ+ + G            G +S +  +    R++GYY++Q +IPS  +V++SW
Sbjct: 201 SHHMRLPQYYMTGVDFFDCTEQRYNGIFSCVRAQFTLERTLGYYMLQAFIPSIALVMVSW 260

Query: 78  VSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLL 137
           V+FW++  A+PARV LG                 +P +SY+K+IDV+  +C   V  +LL
Sbjct: 261 VTFWIDVRASPARVGLGVTIILSVISKTNGVRLDIPPVSYLKAIDVWYTSCLFFVIGALL 320

Query: 138 EYATVGYMAKRIQMRKQRFTA 158
           EYA V +++   +  KQ+  A
Sbjct: 321 EYALVHHLSLGQKKTKQKVLA 341


>UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor
           subunit alpha-3 precursor (GABA(A) receptor subunit
           alpha-3).; n=2; Xenopus tropicalis|Rep:
           Gamma-aminobutyric-acid receptor subunit alpha-3
           precursor (GABA(A) receptor subunit alpha-3). - Xenopus
           tropicalis
          Length = 465

 Score = 92.7 bits (220), Expect = 9e-18
 Identities = 39/106 (36%), Positives = 59/106 (55%)

Query: 43  GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102
           G Y  +       R +GY++IQ Y+P  + VI+S VSFWLNR + PAR   G        
Sbjct: 233 GEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMT 292

Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
                   +LPK++Y  ++D ++  C+  VF++L+E+ATV Y  KR
Sbjct: 293 TLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTKR 338


>UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop
           ligand-gated ion channel subunit; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to cys-loop
           ligand-gated ion channel subunit - Nasonia vitripennis
          Length = 435

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 3/135 (2%)

Query: 11  GPNSVGVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYI 67
           GP+ V V+ E+ L Q+ +   L   +    I    GN+SRL    QF R +G++LIQ + 
Sbjct: 194 GPDGVIVNPELKLLQYNLEDPLKIDESVSFIDEKNGNFSRLIVYFQFERQIGHHLIQTFA 253

Query: 68  PSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGT 127
           PS L+V++SW SFWL  +A P RV+L                + +P ++YVK++D+++  
Sbjct: 254 PSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGLKSDIPPVAYVKALDLWMAG 313

Query: 128 CFVMVFASLLEYATV 142
           C   VF++L E+  V
Sbjct: 314 CMFFVFSALGEFVVV 328


>UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 524

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 40/106 (37%), Positives = 61/106 (57%)

Query: 43  GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102
           GNYS L+  +   R +G+YL+  ++PS LIV ISWVSFWL  +  P R++LG        
Sbjct: 246 GNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFI 305

Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
                    LPK+SY+K  +V+   C + +F S++E+A V  + +R
Sbjct: 306 TLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRR 351


>UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr)
           protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine
           receptor family (See gbr) protein 3 - Caenorhabditis
           elegans
          Length = 438

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 46/158 (29%), Positives = 82/158 (51%), Gaps = 6/158 (3%)

Query: 3   DIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEI-----QFVR 56
           ++R  W +  P ++    +  LP F+             T G + +L         +F R
Sbjct: 187 EVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFSQTFYRFKR 246

Query: 57  SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116
             GYY++Q+Y+P+ L V ISW++FW++  A PAR++LG                 LP++S
Sbjct: 247 LYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFGNIVKNLPRVS 306

Query: 117 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154
           +VK+ID++   C   +F SL+E A VG++ K  +++++
Sbjct: 307 FVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRR 344


>UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 286

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 45/132 (34%), Positives = 70/132 (53%), Gaps = 2/132 (1%)

Query: 11  GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSG 70
           G   + +S EV + Q+ +     R  +    TG +S     I   R + YY+   Y+P+G
Sbjct: 143 GGKGLIISDEVEISQYSITEVTSRDFKGVYNTGVFSEPIATIVLKRRLMYYVYGYYLPAG 202

Query: 71  LIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFV 130
           L+V +SW+SFW++  + PARVSLG                  P +SY  ++DVY+ +C+V
Sbjct: 203 LVVFLSWISFWIDPRSVPARVSLGVITILAMGSFLHGGKG--PSVSYATALDVYIISCYV 260

Query: 131 MVFASLLEYATV 142
            VF SLLE++ V
Sbjct: 261 FVFTSLLEFSLV 272


>UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 290

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 2/124 (1%)

Query: 19  SEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 78
           S V LP+  +  ++  ++   L  GN+SR+     F R + Y L+QIY P+ LIV +SW+
Sbjct: 169 STVVLPRISI--YKSMSLNSVLFVGNWSRVTTTFLFKRQIEYALLQIYAPTMLIVSLSWL 226

Query: 79  SFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 138
           SFW+++ A PARV+LG                  PK+SY+K+ID +    FV VF + +E
Sbjct: 227 SFWISKEAVPARVTLGVTTILTIVTLIGSFRFQFPKVSYIKAIDWFFIVSFVFVFGAQIE 286

Query: 139 YATV 142
           +  V
Sbjct: 287 FIAV 290


>UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric acid
           A receptor, alpha 2 isoform 2; n=2; Euteleostomi|Rep:
           PREDICTED: gamma-aminobutyric acid A receptor, alpha 2
           isoform 2 - Macaca mulatta
          Length = 403

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 38/104 (36%), Positives = 59/104 (56%)

Query: 45  YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104
           Y+ +       R +GY++IQ Y+P  + VI+S VSFWLNR + PAR   G          
Sbjct: 189 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 248

Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
                 +LPK++Y  ++D ++  C+  VF++L+E+ATV Y  KR
Sbjct: 249 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 292


>UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 194

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 40/96 (41%), Positives = 63/96 (65%)

Query: 65  IYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVY 124
           IY+PS LIVI+SWVSFW++R  T AR+++G                +LPK+SYVKS++++
Sbjct: 1   IYLPSYLIVILSWVSFWVDREQTAARIAMGITTVLTMATLIGSARVSLPKVSYVKSLELF 60

Query: 125 LGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQ 160
           L  CF+ VF+++LEY+ V Y+  R +++ +   A Q
Sbjct: 61  LIMCFLFVFSAILEYSFVSYLVFRQRVKNREDYAQQ 96


>UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 349

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 52/156 (33%), Positives = 88/156 (56%), Gaps = 5/156 (3%)

Query: 2   RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAM--EISLTTGNYSRLACEIQFVRSMG 59
           ++I Y+W + P  V V ++ +L QF +  + + +   EI    GNYS L  +  F R +G
Sbjct: 101 KNIVYRW-QSPLGVTVRNK-NLAQF-IFTYLELSEYEEIYGMMGNYSILQVDFAFKRRLG 157

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           Y+LIQ+Y P   +V++SW+ FW++++    R++LG              NAA+P++SY K
Sbjct: 158 YFLIQVYAPDIFVVLLSWIVFWMDKDDMGNRMALGITTILTIMFLLGSVNAAMPRVSYPK 217

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 155
           ++D YL   F +VF  L+E   V  ++K    R++R
Sbjct: 218 ALDWYLMVSFSLVFLVLIECMIVFVISKYKNDRRKR 253


>UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila
           melanogaster|Rep: CG33989-PD, isoform D - Drosophila
           melanogaster (Fruit fly)
          Length = 737

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 42/145 (28%), Positives = 76/145 (52%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           I+Y W    +++  S  ++     ++ ++  A + +   GNYS L  E+ F R   YY  
Sbjct: 490 IKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFT 549

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
            ++IP  ++V  S+++FWL  NA PARV +G               + LP +S + +++V
Sbjct: 550 TVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNV 609

Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148
           + G C   ++ASLLE+  V Y+ ++
Sbjct: 610 WDGVCMCFIYASLLEFVCVNYVGRK 634


>UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14573, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 371

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 37/92 (40%), Positives = 62/92 (67%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI + W  G  +V    ++ LPQF ++ ++  +  +  +TG+Y RL+   +  R++GY++
Sbjct: 232 DIEFYWRGGDGAVSGVDKIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRNIGYFI 291

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94
           +Q Y+PS LI I+SWVSFW+N +A+ ARV+LG
Sbjct: 292 LQTYMPSILITILSWVSFWINYDASAARVALG 323


>UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 508

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 45/117 (38%), Positives = 64/117 (54%), Gaps = 1/117 (0%)

Query: 31  HRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR 90
           H+ R  E     G +  L    +F R  G+Y++Q Y+P+ L + ISW+SF L   A PAR
Sbjct: 245 HKIRTTE-EYPAGYWHELTMSFEFKRRAGWYILQAYLPTYLTICISWISFALGSKAIPAR 303

Query: 91  VSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147
             LG                 LP++SYVK+IDV++ +C   VF SLLE A VGY+++
Sbjct: 304 TMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWMLSCMTFVFCSLLELAWVGYLSR 360


>UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p -
           Drosophila melanogaster (Fruit fly)
          Length = 449

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 51/165 (30%), Positives = 88/165 (53%), Gaps = 9/165 (5%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAME----ISLTTGNYSRLACEIQFVRSMG 59
           ++ +W++  + V ++ E+ L Q+  LG      E    +    GN+SRL    +F R +G
Sbjct: 191 VKLRWSD--SGVTLNPELKLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIG 247

Query: 60  YYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVK 119
           ++LIQ + PS L+V++SW SFWL  +A P RV+L                A +P ++YVK
Sbjct: 248 HHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTL--LVTCMLTLVTMFTGADIPPVAYVK 305

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAV 164
           ++D+++  C + VFA+L E+  V  +  + Q +  R   V  M +
Sbjct: 306 ALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRI 350


>UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor
           alpha-like precursor (GABA(A) receptor alpha-like and
           glycine receptor-like subunit of Drosophila); n=3;
           Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like
           precursor (GABA(A) receptor alpha-like and glycine
           receptor-like subunit of Drosophila) - Drosophila
           melanogaster (Fruit fly)
          Length = 686

 Score = 90.6 bits (215), Expect = 4e-17
 Identities = 43/103 (41%), Positives = 58/103 (56%)

Query: 45  YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104
           YS L       R MG +LIQ+Y P  L+V++SWVSFWLNR AT  RVSLG          
Sbjct: 378 YSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 437

Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147
                  LPK+SY  ++D ++   F  +FA++L++A V Y  K
Sbjct: 438 GLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTK 480


>UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 517

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 46/137 (33%), Positives = 66/137 (48%)

Query: 17  VSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIIS 76
           +  E+ LP F +  +           G ++ L     F R  G+Y+ Q YIP+ L + IS
Sbjct: 233 LKKEIVLPDFVMSNYSTSLKHEIYPAGVWNELTMTFVFSRRYGWYIFQAYIPTYLTIFIS 292

Query: 77  WVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 136
           W+SF L     PAR  LG                 LP++SYVK++DV++  C   VF SL
Sbjct: 293 WISFCLGPKMIPARTMLGVNSLLALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFVFCSL 352

Query: 137 LEYATVGYMAKRIQMRK 153
           LE A +G M  R + R+
Sbjct: 353 LELAIIGSMGARSENRQ 369


>UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4;
           Caenorhabditis|Rep: Serotonin-gated chloride channel -
           Caenorhabditis elegans
          Length = 489

 Score = 89.4 bits (212), Expect = 8e-17
 Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 2/145 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++   W E   +V +   + LP F ++ +  +   +    G + +L     F R  G+Y+
Sbjct: 186 EVELHWME--EAVTLMKPIQLPDFDMVHYSTKKETLLYPNGYWDQLQVTFTFKRRYGFYI 243

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQ Y+P+ L +I+SWVSF +   A PAR ++G                 LP++SYVK++D
Sbjct: 244 IQAYVPTYLTIIVSWVSFCMEPKALPARTTVGISSLLALTFQFGNILKNLPRVSYVKAMD 303

Query: 123 VYLGTCFVMVFASLLEYATVGYMAK 147
           V++  C   VF +++E A V Y+++
Sbjct: 304 VWMLGCISFVFGTMVELAFVCYISR 328


>UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep:
           CG11340-PA - Drosophila melanogaster (Fruit fly)
          Length = 526

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 13/163 (7%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGH---------RQRAMEISLTTGNYSRLACEIQF 54
           ++  W E  N V    ++ L ++ ++G           +  M      GNYS ++  +  
Sbjct: 235 VQLHW-ETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLL 293

Query: 55  VRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPK 114
            R +GYY+I  ++PS +IV ISWVSFWL  + TPAR +LG                 L K
Sbjct: 294 TREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMK 353

Query: 115 ISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR---IQMRKQ 154
           +SYV   +V+   C + +F SL+E+A V  + +R   +Q++K+
Sbjct: 354 VSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKR 396


>UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG6927-PA - Tribolium castaneum
          Length = 464

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 55/172 (31%), Positives = 92/172 (53%), Gaps = 16/172 (9%)

Query: 7   KWNEGPNSVGVSSEVSLPQFKV------LGHRQ---RAMEISLTTGNYSRLACEIQFVRS 57
           +WN+   S+ VS  +   +F V       G      +  ++S   G++S L  + +F R 
Sbjct: 193 EWNKKSESLNVSDNLHFTEFIVDEIKCDTGTNDGPYQNRDMSDQVGSFSELVIKFRFHRD 252

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
           +GYYL+  +IPS L+V  +WV+FWL  +A P R +LG              +  +PK+SY
Sbjct: 253 IGYYLLDFFIPSYLLVCTAWVTFWLQADAGPPRATLGATTVVAFITLHLGMSKDIPKVSY 312

Query: 118 VKSIDV-YLG-TCFVMVFASLLEYATVGYMAKR---IQMRKQRFTAVQKMAV 164
           +K+ D+ +LG +CF  +F SL E+A V  + +R   I+++K +   + K AV
Sbjct: 313 IKASDIWFLGVSCF--IFFSLAEFAFVNVIWRRKKIIELKKPKQKYIIKAAV 362


>UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 428

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 6/147 (4%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++  +W + P  + +   + LP F +              G +S L     F R  G+YL
Sbjct: 212 EVFMRWGDPP--LTIFKPIELPDFTMTNFSTSNKFQLYAAGYWSELNVNFLFRRRSGWYL 269

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q YIP+ + V ISW+ F+L   A PAR  +G                 LP++SY+K+ID
Sbjct: 270 LQGYIPTYMTVFISWIPFYLGPKAIPARTMIGVNALLALTFQFGNIIRNLPRVSYIKAID 329

Query: 123 VYL--GTCFVMVFASLLEYATVGYMAK 147
           V++  G CF  VFASL E AT+G++ +
Sbjct: 330 VWMLSGICF--VFASLFELATIGFLMR 354


>UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG6927-PA - Tribolium castaneum
          Length = 534

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 7/147 (4%)

Query: 8   WNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLT------TGNYSRLACEIQFVRSMGYY 61
           W++  N V ++  + L +F + G   +   +  +       GN+S L  +    R +GYY
Sbjct: 243 WDKN-NPVKIAKNLHLTEFVLSGSLPQETVVPASFNNGAFVGNFSELVFKFTLKREVGYY 301

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSI 121
           ++  ++PS L+V  SWV+FWL  +A+  RV+LG              N  LPK+SY+K+ 
Sbjct: 302 VMDYFLPSILLVCTSWVTFWLQADASAPRVTLGTSTMLAFITLNGGINKNLPKVSYIKAS 361

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKR 148
           +++   C   +F S+ E+A V  + +R
Sbjct: 362 EIWFLACACFIFCSMAEFAFVNVIWRR 388


>UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to
           gamma-aminobutyric acid receptor rho1 subunit; n=1; Bos
           taurus|Rep: PREDICTED: similar to gamma-aminobutyric
           acid receptor rho1 subunit - Bos taurus
          Length = 299

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 37/79 (46%), Positives = 51/79 (64%), Gaps = 1/79 (1%)

Query: 77  WVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 136
           WVSFW++R A PARV LG              NA++P++SY+K++D+YL   FV VF S+
Sbjct: 120 WVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSV 179

Query: 137 LEYATVGYMAKRIQMRKQR 155
           LEYA V Y+   +Q RK+R
Sbjct: 180 LEYAAVNYLT-TVQERKER 197


>UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor
           subunit beta-1 precursor (GABA(A) receptor subunit
           beta-1).; n=1; Gallus gallus|Rep:
           Gamma-aminobutyric-acid receptor subunit beta-1
           precursor (GABA(A) receptor subunit beta-1). - Gallus
           gallus
          Length = 382

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 3/165 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           DI + WN G ++V   S + LPQF ++ ++  +  +   TG Y +L+      R+ GY+ 
Sbjct: 106 DIEFYWNGGKSAVTGVSNIELPQFSIVDYKTVSKRVEFPTGTYPQLSLSFWLKRNTGYFT 165

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLG-XXXXXXXXXXXXXXNAALPKISYVKSI 121
           +Q ++PS LI I+S VSFW+N +A+ ARV+LG               +  L      K  
Sbjct: 166 LQTHMPSTLITILSRVSFWIN-DASAARVALGITTVLTMTTISTHLLSQMLGFFPQTKFK 224

Query: 122 DVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR-FTAVQKMAVE 165
            +     ++ ++   L+YA  G   K   M K R  T + K+ VE
Sbjct: 225 QITSTLPYIYIYLFKLDYAIKGSSCKDQSMNKVRHITEMSKLMVE 269


>UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16;
           Endopterygota|Rep: CG33989-PF, isoform F - Drosophila
           melanogaster (Fruit fly)
          Length = 779

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 39/145 (26%), Positives = 75/145 (51%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           I+Y W    +++  S  ++     ++ ++  A + +   GNYS L  ++ F R   +Y  
Sbjct: 515 IKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDLIFTRDRAFYFT 574

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
            ++IP  ++V  S+++FWL  NA PAR  +G               + LP +S + +++V
Sbjct: 575 TVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNV 634

Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148
           + G C   ++ASLLE+  V Y+ ++
Sbjct: 635 WDGVCMCFIYASLLEFVCVNYVGRK 659


>UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like
           protein T20B12.9; n=2; Caenorhabditis|Rep:
           Uncharacterized glycine receptor-like protein T20B12.9 -
           Caenorhabditis elegans
          Length = 476

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 2/140 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++R  W++ P  + +  +V LP F ++G       +    G + R   +  F R  G+YL
Sbjct: 169 EVRLMWHDVP--ITMMEKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYL 226

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
            Q Y P+ L VI SWV F+ +  +  AR++LG                 LP++SY+K +D
Sbjct: 227 FQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLD 286

Query: 123 VYLGTCFVMVFASLLEYATV 142
           V++    + +F +L+E A V
Sbjct: 287 VWMIFSVIFIFCTLVELAIV 306


>UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 563

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 47/152 (30%), Positives = 81/152 (53%), Gaps = 7/152 (4%)

Query: 4   IRYKWNEGPNS--VGVSSEVSLPQFKVLGHR--QRAMEISLTTGN--YSRLACEIQFVRS 57
           +   W + P +  +G + ++ L   ++   R  + A    +  G   +S +   I   R 
Sbjct: 276 VNLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKCAGPYPMFRGEAAWSCIQGYIVMKRL 335

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
           + +++IQ YIP+G++V ISW+SFWL+  A+PAR+SL                  LP++SY
Sbjct: 336 VLFHIIQTYIPTGMLVSISWMSFWLDPRASPARISLTITSLLTLTTMSNGARQDLPQVSY 395

Query: 118 VKSIDVYLGTCFVMVFASLLEYATVG-YMAKR 148
           +K++D++L     ++F  LLEY+ V  YM KR
Sbjct: 396 IKALDIWLTFSQALIFLVLLEYSFVSYYMTKR 427


>UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.16;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T15B7.16 - Caenorhabditis elegans
          Length = 435

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 39/115 (33%), Positives = 65/115 (56%)

Query: 47  RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXX 106
           +L   + F R+ G+Y++Q+YIP+   V +S+VSFW++  A PAR++LG            
Sbjct: 247 QLTVSLTFSRAYGFYILQMYIPTYSSVFLSFVSFWIDLKALPARITLGVSSLMALTFQYG 306

Query: 107 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQK 161
                LP++ YVKSIDVY+      +F +++E A V Y+     +R++   A +K
Sbjct: 307 NVAKNLPRVGYVKSIDVYMVLTTAFIFLTMIEVAFVCYLDSENNLRRKERQAEKK 361


>UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4;
           n=2; Apocrita|Rep: PH-sensitive chloride channel variant
           4 - Apis mellifera (Honeybee)
          Length = 489

 Score = 83.0 bits (196), Expect = 7e-15
 Identities = 37/125 (29%), Positives = 65/125 (52%)

Query: 43  GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102
           GNYS L  ++ F R   +Y   ++IP  ++V  S+++FWL  NA PARV +G        
Sbjct: 285 GNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFF 344

Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162
                  + LP +S + +++V+ G C   ++ASLLE+  V Y+ ++  M    +   +  
Sbjct: 345 TTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPMHNVVYRPGENP 404

Query: 163 AVEKK 167
             +K+
Sbjct: 405 VTQKR 409


>UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein acc-4 - Caenorhabditis elegans
          Length = 408

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 44/132 (33%), Positives = 71/132 (53%), Gaps = 2/132 (1%)

Query: 17  VSSEVSLPQFKVLGHRQRAMEISL-TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVII 75
           +   ++LP + VL     + E+ L   G ++ L     F R  G+Y++Q+Y+P+ + V I
Sbjct: 220 LKGNITLPDY-VLVDFSSSSELRLYPPGIFNELIATFTFQRLYGFYILQVYVPAYISVFI 278

Query: 76  SWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFAS 135
           SWVSF L     P+R ++G                 LPK S VK+IDV++ +    +FAS
Sbjct: 279 SWVSFTLGAEQIPSRTTVGVNSLLALTFQFGAVVNNLPKTSDVKAIDVWILSSMAFIFAS 338

Query: 136 LLEYATVGYMAK 147
           L+E A VGY+++
Sbjct: 339 LIELAVVGYLSR 350


>UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 428

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 40/115 (34%), Positives = 63/115 (54%)

Query: 43  GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102
           GN+S +       RS  Y+L  +Y  S +IV ISW+ F +  + T AR+++G        
Sbjct: 228 GNFSAVVAVFSIERSYTYFLTHVYGTSCVIVFISWMGFVIPPDQTAARIAVGVTTLLTQV 287

Query: 103 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFT 157
                 N+++PK+SYVKSID +L +C + VF SL+EY  +  +  +   R Q+ T
Sbjct: 288 TVINILNSSMPKVSYVKSIDKFLISCLIFVFLSLIEYCVILILDGKRTRRHQQHT 342


>UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF15015, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 201

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 33/88 (37%), Positives = 53/88 (60%), Gaps = 1/88 (1%)

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS-YVKSID 122
           + Y+PS L+V++SWVSFW+++++ PAR  +G                +LP  + ++K+ID
Sbjct: 2   ETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAID 61

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQ 150
           VYLG CF  +F +LLEYA   +   + Q
Sbjct: 62  VYLGICFTFIFGALLEYACAHFYTMQHQ 89


>UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 273

 Score = 79.8 bits (188), Expect = 7e-14
 Identities = 37/123 (30%), Positives = 66/123 (53%), Gaps = 1/123 (0%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           +I YKW  G  +V V ++  L QF +       M  +  TG++  +     F R +GY++
Sbjct: 152 NIIYKWKTGKPAVEVGTK-DLAQFDMKTVEISNMTDTFVTGDFEAIIVTFTFKRRLGYFI 210

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           IQ++ P   +V++SW+ FW++R     R++LG              N+++P++SY K++D
Sbjct: 211 IQVFAPDIFVVMLSWIVFWMDREDMGNRMALGITIILTIMFLLGAINSSMPRVSYPKALD 270

Query: 123 VYL 125
            YL
Sbjct: 271 WYL 273


>UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 400

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 3/160 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++R +WN   + V    E+ +  F +       ++     G +  L     F R   +Y 
Sbjct: 225 EVRLQWNSQRSPVFALQEIRIADFWLKDITPAVIKRDYPAGLWDELVVTFVFERRYMWYF 284

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q Y+P+   + ISW++F L   A   R  +G                 LP++SY+K+ID
Sbjct: 285 LQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGSIMKNLPRVSYIKAID 344

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKM 162
           V++ +    VF SL+E A VGY   ++Q+++++   ++K+
Sbjct: 345 VWMLSSMTFVFLSLIELAIVGY---KLQIQREKEHVIEKV 381


>UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 93

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 33/93 (35%), Positives = 54/93 (58%)

Query: 40  LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXX 99
           + +G +  +     F R++GY L+Q+Y P+ LIV +SW++FW+ R+A PAR++L      
Sbjct: 1   IVSGAWIHITASFVFNRNIGYSLLQVYAPTTLIVALSWLAFWIPRDAVPARITLSVTTIL 60

Query: 100 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 132
                        PK+SYVK++DV+L   F+ V
Sbjct: 61  TIVTLMGSFRTQFPKVSYVKAVDVFLIVSFLFV 93


>UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor
           subunit rho-1 precursor (GABA(A) receptor subunit
           rho-1).; n=1; Takifugu rubripes|Rep:
           Gamma-aminobutyric-acid receptor subunit rho-1 precursor
           (GABA(A) receptor subunit rho-1). - Takifugu rubripes
          Length = 477

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLACEIQFVRSMGYY 61
           D+   W  G  S+ +   +SL QF +   H    +    +TG Y+RL       R + ++
Sbjct: 208 DLMLYWKSGDESLSIDDRISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFF 267

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94
           L+Q Y P+ L+V++SWVSFW++R A PARVSLG
Sbjct: 268 LLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 300


>UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG06736 - Caenorhabditis
           briggsae
          Length = 394

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 41/146 (28%), Positives = 64/146 (43%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++R +WN     V     + L  F +       +      G +  L     F R   +Y 
Sbjct: 219 EVRLQWNSQRKPVFAIQPIRLADFTLKDITTGTISRDYPAGKWDELIVTFVFERRYMWYF 278

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
           +Q Y+P+   + ISW++F L   A   R  +G                 LPK+SY+K+ID
Sbjct: 279 LQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGSIMKNLPKVSYIKAID 338

Query: 123 VYLGTCFVMVFASLLEYATVGYMAKR 148
           V++    + VF SL+E A VGY  +R
Sbjct: 339 VWMLGSMLFVFLSLVELAVVGYTLQR 364


>UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 536

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%)

Query: 3   DIRYKWNEGPNSVGVS----SEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 58
           +++YKW    +  GV     S   LPQF + G +            YS L     F R  
Sbjct: 217 EVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPANITRDKEYSALEVRFYFDRHF 276

Query: 59  GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYV 118
           GY+L+  Y+P  L+V++ WV+F+  R AT  R+ +G               +  PK+   
Sbjct: 277 GYFLMNFYVPCALVVLLCWVAFFTKREATAERIGIGITNVLTIVLISMDSKSDSPKVDSP 336

Query: 119 KSIDVYLGTCFVMVFASLLEYATVGYMAK 147
            +++V++  C++     ++E+  V Y  K
Sbjct: 337 TALEVFIWICYLTHLICMVEFTVVHYHTK 365


>UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 618

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 4/153 (2%)

Query: 4   IRYKWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYL 62
           ++ +W    N ++ +   V +P+  +             +G YS L  +    R +GY++
Sbjct: 402 VKLEWFSDTNDAIWIEKNVKIPELSIRHLHPDTCNGVRKSGVYSCLEAKFYMHREVGYHI 461

Query: 63  IQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSID 122
              YIP+ + V+ SW+S WL       R+ +                  LPK+SYVK+ID
Sbjct: 462 ANTYIPTAICVVFSWISVWLPEEFVEGRIFVSLTVFLTLSAENNSAKEELPKVSYVKAID 521

Query: 123 VYLGTCFVMVFASLLEYATV---GYMAKRIQMR 152
           ++ G     VF ++L+   V    + +KR++++
Sbjct: 522 IWFGFTSTFVFLTMLQALVVISLEHNSKRLRLK 554


>UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14565, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 502

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 35/115 (30%), Positives = 64/115 (55%), Gaps = 2/115 (1%)

Query: 3   DIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRA-MEISLTTGNYSRLACEIQFVRSMGYY 61
           D+   W  G +S+  + E+ L QF +   +  + +    +TG Y+RL       R + ++
Sbjct: 212 DLMLYWKNGNDSLR-TDEIVLSQFFIEQFQASSGLAFYSSTGWYNRLFISFLLRRHIFFF 270

Query: 62  LIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116
           ++Q Y P+ L+V++SWVSFW++R A PARVSLG              ++++P+++
Sbjct: 271 MLQTYFPTMLMVVLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVSSSMPQVT 325



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/59 (42%), Positives = 37/59 (62%), Gaps = 7/59 (11%)

Query: 114 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR-------FTAVQKMAVE 165
           ++SYVK++D+YL T F++VF S++EYA V Y     +MRK +       F A Q MA +
Sbjct: 358 QVSYVKAVDIYLWTSFLLVFLSVIEYAAVNYCTTLEEMRKMKRGKIPSTFNATQAMAFD 416


>UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome
          shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 7
          SCAF8790, whole genome shotgun sequence - Tetraodon
          nigroviridis (Green puffer)
          Length = 66

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 28/54 (51%), Positives = 43/54 (79%)

Query: 41 TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLG 94
          +TG+Y RL+   +  R++GY+++Q Y+PS LI I+SWVSFW+N +A+ ARV+LG
Sbjct: 1  STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 54


>UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Rep:
           GABA-A receptor - Caenorhabditis remanei
          Length = 206

 Score = 66.5 bits (155), Expect = 7e-10
 Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)

Query: 20  EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVS 79
           +V LP+  +  +          +G +S L    +  R +G+++ Q YIP+ L ++ SWV 
Sbjct: 6   DVKLPELYIDRYETTTCANERKSGAFSCLRAVFRLKRDVGFHIAQTYIPTSLALMFSWVG 65

Query: 80  FWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE- 138
            WL       R+ +                  LP +SY+K+ID++ G     VF +LL+ 
Sbjct: 66  VWLPEEFMEGRIGVAITVLLTLSTESAGAREHLPSVSYLKAIDLWFGFITGFVFFTLLQT 125

Query: 139 YATVGYMAKRIQMRK 153
              +G+  +  Q++K
Sbjct: 126 LFVIGFDKRANQLKK 140


>UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 409

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 2/114 (1%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           + + W +G N + + ++  L +F +       ++++   G Y  L     F R +G+YLI
Sbjct: 192 VAFHW-KGRNPITIFNK-ELSEFDMEQWLIEEVDMTYVAGKYRNLKVTFIFRRRLGFYLI 249

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY 117
             Y+P  ++VI+SW+ FW++ ++   R+SLG              N+ +P++SY
Sbjct: 250 NFYVPCVVMVIMSWIVFWMDSSSIGERISLGITTILTIVFLLGSSNSTMPRVSY 303


>UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 239

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 26/74 (35%), Positives = 41/74 (55%)

Query: 43  GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXX 102
           GNY+ L+      R +GYY IQ+Y+P   +V++SW+ FW+N   T  R+++G        
Sbjct: 166 GNYTLLSASFPMHRRIGYYAIQMYVPCTFLVMLSWIVFWMNPEETGNRLTVGITTILTIV 225

Query: 103 XXXXXXNAALPKIS 116
                 N+ LPK+S
Sbjct: 226 FLLGYTNSTLPKVS 239


>UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1;
           Aedes aegypti|Rep: Glycine receptor beta, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 439

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 7/148 (4%)

Query: 1   MRDIRYKWNEG-----PNSVGVSSEVSLPQFKVLGH-RQRAMEISLTTGNYSRLACEIQF 54
           +R++R++W        P   G      LP++ V  +  Q    I     N+S    EI  
Sbjct: 141 VREMRFRWKNDNGLIFPKDFG-DGFFRLPKYVVSFYTEQNPQTIHYGEDNHSSARLEITL 199

Query: 55  VRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPK 114
            R +  YL++ Y+PS L V +SW SF +     P R+ L                   P 
Sbjct: 200 SREVKSYLLENYLPSTLFVSMSWGSFVVVPEIVPGRMVLLVTTLLSLITMFDTVRNNSPD 259

Query: 115 ISYVKSIDVYLGTCFVMVFASLLEYATV 142
              +K ++V+L +C + VF +L+EY  V
Sbjct: 260 ALELKCLEVWLISCTLFVFFALMEYFIV 287


>UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel
           ligand-binding; n=2; Chroococcales|Rep:
           Neurotransmitter-gated ion-channel ligand-binding -
           Crocosphaera watsonii
          Length = 340

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 2/128 (1%)

Query: 16  GVSSEVSLPQFKVLG--HRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIV 73
           G+SSE+SL  + ++G      A  +     +Y+R   EI+  R   +Y  ++  P  LIV
Sbjct: 173 GISSEISLVNWSIIGLSSHSHAHYLQPEQQDYARFDYEIKVKRHSSFYAWRVLFPVALIV 232

Query: 74  IISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVF 133
            +S + FWL       +++L                  LPK++Y+ + D  +    ++VF
Sbjct: 233 FMSDLVFWLEPTQIIPQITLATATMVSLITYQFILRQELPKMNYLTAEDKVIVGSMLLVF 292

Query: 134 ASLLEYAT 141
            +L++  T
Sbjct: 293 IALVKSVT 300


>UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1;
           Roseobacter sp. AzwK-3b|Rep: Putative uncharacterized
           protein - Roseobacter sp. AzwK-3b
          Length = 244

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/98 (27%), Positives = 42/98 (42%)

Query: 46  SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXX 105
           S L   I   R + YYL +I +P   +V +SWV FW+  N    ++ LG           
Sbjct: 108 SMLTLTISADREVNYYLFRIMLPLFFVVAMSWVIFWVPPNRFEFQIGLGATSMLTVIAFN 167

Query: 106 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 143
                +LP + Y+  +D  L     +VF ++ E    G
Sbjct: 168 LAVAGSLPPLGYLTVLDQILIWSIAIVFLAIAEALVTG 205


>UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1;
           Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
           protein - Lyngbya sp. PCC 8106
          Length = 343

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 4/135 (2%)

Query: 16  GVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLI 72
           G++ E+SLP +     + H   +  I+    ++     E++  R   YY+ ++ +P  LI
Sbjct: 178 GLAEEISLPNWSTNIPVAHNG-SRHIAQLNQSFVCFDYELKVKRYTAYYITRVILPLILI 236

Query: 73  VIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 132
           V++S+  FW        +V++                 +LP++ Y+  +D ++    V+V
Sbjct: 237 VLMSYAVFWFPPGQIMPQVTISVTAILSLITYEFTLQQSLPQVPYLTVLDKFVIGAMVLV 296

Query: 133 FASLLEYATVGYMAK 147
           F +L+E  T   +A+
Sbjct: 297 FLALVETVTTIELAE 311


>UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit
           precursor; n=3; Chromadorea|Rep: Ligand-gated chloride
           channel subunit precursor - Dirofilaria immitis (Canine
           heartworm)
          Length = 406

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 5/146 (3%)

Query: 1   MRDIRYKWNEGPNSV---GVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 57
           + DI Y W   P +V    VS E+    ++           + T G YS +   I F  +
Sbjct: 189 IEDIVYLWANSPPTVIPVEVSQELLTGFYEFKEAVAEDCAGNYTIGIYSCIDVLITFTGA 248

Query: 58  MGYYLIQIYIPSGLIVIISWVSFWLNRN-ATPARVSLGXXXXXXXXXXXXXXNAALPKIS 116
                 +I+IPS L++++SW+ FW++ + + P  +S                   L    
Sbjct: 249 SSEAFWRIFIPSILLILVSWLHFWVHGSWSVPRTISAAVPFLIFVSILIFYPQPNLTTYG 308

Query: 117 YVKSIDVYLGTCFVMVFASLLEYATV 142
            V S+ ++L  C +  FASL+EY  V
Sbjct: 309 -VSSLQIWLFFCLIFTFASLVEYFIV 333


>UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1;
           Drosophila sp.|Rep: Gamma-aminobutyric acid A receptor -
           Drosophila sp. (Fruit fly)
          Length = 210

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 34/63 (53%), Positives = 39/63 (61%), Gaps = 11/63 (17%)

Query: 33  QRAMEISLTTGNYSRLACEIQ-FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARV 91
           QRA EI+LTTGNYSRLACEIQ FV  M +  +  Y   G +           RNATPARV
Sbjct: 106 QRATEINLTTGNYSRLACEIQCFV--MVFASLLEYATVGYMA--------KRRNATPARV 155

Query: 92  SLG 94
           +LG
Sbjct: 156 ALG 158



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 21/21 (100%), Positives = 21/21 (100%)

Query: 128 CFVMVFASLLEYATVGYMAKR 148
           CFVMVFASLLEYATVGYMAKR
Sbjct: 127 CFVMVFASLLEYATVGYMAKR 147


>UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1;
           Danio rerio|Rep: glycine receptor, beta b - Danio rerio
          Length = 451

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 20/34 (58%), Positives = 26/34 (76%)

Query: 112 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 145
           LPK+SYVK+ID++L  C +  FASL+EYA V  M
Sbjct: 276 LPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVM 309


>UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 394

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 45  YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXX 104
           +S     +   R  GYYL +I IP  +IV  +W +FW+       R+             
Sbjct: 257 FSEYVYSVNVDRDPGYYLYKIVIPLLIIVAFNWATFWMPGEPASVRMERTVIALLTVVAF 316

Query: 105 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLL 137
                  LP+I Y+  +D  +   F  V  ++L
Sbjct: 317 HQVVATNLPRIGYLTFMDGIVYVAFASVGLTML 349


>UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Glra4a protein -
           Strongylocentrotus purpuratus
          Length = 541

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 22/75 (29%), Positives = 38/75 (50%)

Query: 56  RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKI 115
           R  G+Y+  I +   LIVI+++ SF + R A   R+S+               + +LP I
Sbjct: 299 RRPGFYIWNIALIMLLIVILTFTSFVVERGAPADRLSVTVTLLLTAVAFKYVVSQSLPLI 358

Query: 116 SYVKSIDVYLGTCFV 130
           SY+  +D Y+ +C +
Sbjct: 359 SYLTMLDKYVLSCLI 373


>UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole
           genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome
           undetermined SCAF15016, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 269

 Score = 39.9 bits (89), Expect = 0.067
 Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 1/35 (2%)

Query: 111 ALPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGY 144
           +LP  + ++K+IDVYLG CF  +F +L+EYA   +
Sbjct: 232 SLPNANCFIKAIDVYLGICFSFIFGALIEYAVAHF 266


>UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 679

 Score = 38.7 bits (86), Expect = 0.15
 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 4/145 (2%)

Query: 4   IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLI 63
           +++ W+  P  +   S+++LP+  +   +           + S L       R    ++I
Sbjct: 472 VKFHWHSNP--IKFQSKITLPELHITKIKTAECSTKGKLVDASCLRIIFSLERDSARFVI 529

Query: 64  QIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDV 123
           + Y+PS L ++ +WV+ ++  N    R+                      + SY+ SIDV
Sbjct: 530 EKYVPSTLAMMFAWVAPYVPYNYEDVRIITPITVLLTLVQMEKGDKEI--RTSYLTSIDV 587

Query: 124 YLGTCFVMVFASLLEYATVGYMAKR 148
           +          SLLE   V  + KR
Sbjct: 588 WFAAMKSFTVLSLLESLAVLALIKR 612


>UniRef50_A7I712 Cluster: Putative uncharacterized protein
           precursor; n=1; Candidatus Methanoregula boonei 6A8|Rep:
           Putative uncharacterized protein precursor -
           Methanoregula boonei (strain 6A8)
          Length = 337

 Score = 38.7 bits (86), Expect = 0.15
 Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 9/135 (6%)

Query: 13  NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFVRSMGYYLIQIYIPSG 70
           N+ G+  E +LP + + G        +   G   YSR+       R     L++ ++P  
Sbjct: 167 NNTGLDDEANLPGWSLTGMSAEVTNRTYVEGEVPYSRVTFSNGIERDTASTLLKFFLPIT 226

Query: 71  LIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFV 130
           LI+I+S  S  +    T +R+ L                 A+P ++Y   +D+++    +
Sbjct: 227 LIIIVSLASLLMK---TSSRLGLNGSMFLAAVLIHWRIADAIPLVAYATFLDLFM----I 279

Query: 131 MVFASLLEYATVGYM 145
           + +A+L+     G +
Sbjct: 280 ITYATLVMVCVSGIL 294


>UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic
           acetylcholine receptor beta 1 subunit variant 1; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           nicotinic acetylcholine receptor beta 1 subunit variant
           1 - Strongylocentrotus purpuratus
          Length = 472

 Score = 38.3 bits (85), Expect = 0.20
 Identities = 16/39 (41%), Positives = 25/39 (64%)

Query: 44  NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL 82
           NYS++  EI   R   Y++I + +PS LI  +S V+FW+
Sbjct: 218 NYSKIHFEITLTRKSYYFVINLVLPSSLINAMSLVAFWV 256


>UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1;
           Synechococcus sp. WH 7805|Rep: Putative uncharacterized
           protein - Synechococcus sp. (strain WH7805)
          Length = 386

 Score = 37.1 bits (82), Expect = 0.47
 Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 5/122 (4%)

Query: 15  VGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL 71
           V +S    LP++K+   R   +   +    +  +SRL+  I   R  GYY+ +I++P G+
Sbjct: 216 VSLSRNARLPEWKIKDLRYVIKNHDDPEKGSKEFSRLSSTITISRRSGYYIYKIFLPLGI 275

Query: 72  IVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVM 131
           +   S     +  +A   R++                 +++P++ Y+   D Y  T F+ 
Sbjct: 276 LTFTSIFFLAIPIDAFADRMAFISGLLFTTLAYQIIIASSVPRVPYLTLGDTY--TIFLF 333

Query: 132 VF 133
            F
Sbjct: 334 TF 335


>UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter
           violaceus|Rep: Glr4197 protein - Gloeobacter violaceus
          Length = 359

 Score = 36.7 bits (81), Expect = 0.62
 Identities = 26/119 (21%), Positives = 46/119 (38%), Gaps = 3/119 (2%)

Query: 46  SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXX 105
           S+L  +++  R    Y+  I +P   I+ ISW +FW    +  A V+L            
Sbjct: 224 SKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLVVSTLIAHIAFN 281

Query: 106 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQ-MRKQRFTAVQKMA 163
                 LPK  Y+      +   ++  F +++E     Y+    Q  R    T   ++A
Sbjct: 282 ILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIA 340


>UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform
           b; n=4; Caenorhabditis|Rep: Acetylcholine receptor
           protein 17, isoform b - Caenorhabditis elegans
          Length = 515

 Score = 36.7 bits (81), Expect = 0.62
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 5/93 (5%)

Query: 56  RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVSLGXXXXXXXXXXXXXXNAAL 112
           R+  YYL  + IPS  I I++ + F+   ++T     +VSLG              +  L
Sbjct: 243 RNPSYYLFTLIIPSAFITIVTVIGFFTPHSSTGENTEKVSLGVTALLSLAIILMMVSDKL 302

Query: 113 PKISYVKSI--DVYLGTCFVMVFASLLEYATVG 143
           P  S    +    Y+G  F+M  A+     T+G
Sbjct: 303 PATSNSVPLLGQYYIGLIFIMFLATYCTTFTLG 335


>UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein acr-18 - Caenorhabditis elegans
          Length = 510

 Score = 36.7 bits (81), Expect = 0.62
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 56  RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVSLGXXXXXXXXXXXXXXNAAL 112
           RS  YY+  + IPS  I +++ V F+   + T     +VSLG              +  +
Sbjct: 235 RSPSYYIFSLVIPSAFITVVTIVGFFTPHSTTGENTEKVSLGVTALLSMAIIMMMVSDEV 294

Query: 113 PKISYVKSI--DVYLGTCFVMVFASLLEYATVGYMAK 147
           P  S V  +    Y+G  F++  A+     T+ Y  +
Sbjct: 295 PATSEVIPLIGKYYIGLIFLIFMAAFTTTLTLSYQMR 331


>UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal
           acetylcholine receptor subunit alpha-9 precursor; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           neuronal acetylcholine receptor subunit alpha-9
           precursor - Strongylocentrotus purpuratus
          Length = 510

 Score = 36.3 bits (80), Expect = 0.82
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 9   NEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYI 67
           NE PN SV + + V   Q  V   +        T   YS++  E+   RS G+Y++ I +
Sbjct: 258 NEDPNQSVFLQNGVWSLQNSVAHQKNETYACCETP--YSQIVYELILERSYGFYVLNIVL 315

Query: 68  PSGLIVIISWVSFWL 82
           PSGL+  ++ + F L
Sbjct: 316 PSGLLAFVNCLVFLL 330


>UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E;
           n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor
           3E - Homo sapiens (Human)
          Length = 471

 Score = 36.3 bits (80), Expect = 0.82
 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 8/117 (6%)

Query: 25  QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 82
           ++++LG  +   ++S     Y ++   +   R    Y+I + +PSG +V I  +SF+L  
Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288

Query: 83  -NRNATPARVSLGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 138
            + N  P +++L               +  LP  S    I VY   C  ++  SLLE
Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340


>UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 404

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 19/86 (22%), Positives = 39/86 (45%)

Query: 51  EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNA 110
           E  F R+ G+Y++ + IP+  I ++S V+ +++ N    + ++G                
Sbjct: 254 EATFSRNPGFYIVLVMIPAYFINVLSIVALFMDINNRSEKFTVGMTNIMSMSFILVILAE 313

Query: 111 ALPKISYVKSIDVYLGTCFVMVFASL 136
            LPK   +  + +Y  T   ++  SL
Sbjct: 314 DLPKTKNLPILAIYTVTSLAIMLCSL 339


>UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3
           subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine
           receptor 3 subunit D - Xenopus tropicalis
          Length = 415

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 61  YLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAALPKISY-VK 119
           Y++ + +PS  +++I  +SF+L  ++T  R S                N  LP  +    
Sbjct: 196 YVVNLLVPSAFLMLIDILSFFLPPHSTD-RASFKMTLLLGYTVFLLIMNDLLPSTANGTP 254

Query: 120 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 152
            I +Y   C  ++  SLLE   + ++  R  M+
Sbjct: 255 LIGIYFSVCLALLVLSLLETVIITHVMHRGAMQ 287


>UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2;
           Caenorhabditis elegans|Rep: Ligand-gated ion channel
           protein 1 - Caenorhabditis elegans
          Length = 371

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 22/113 (19%), Positives = 51/113 (45%), Gaps = 1/113 (0%)

Query: 43  GNYSRLACEIQFV-RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXX 101
           GN+S +   +  + R+ G+Y+  + +P+  I  +S ++  LN      ++++G       
Sbjct: 218 GNFSAVQRFVARIERNPGFYVTLVMVPAFFINFLSIIALCLNIENVGEKITVGLTNIMAM 277

Query: 102 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 154
                     LPK   +  + +Y+    V+V AS+    T+  +   ++ R++
Sbjct: 278 TFILVILAQDLPKTKRIPLLAIYVIVGLVIVMASIGVVLTLPLIRNHLKKRQK 330


>UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD)
           alternative variant a; n=5; Caenorhabditis|Rep:
           Acetylcholine receptor 20 (63.9 kD) alternative variant
           a - Caenorhabditis elegans
          Length = 553

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 23/109 (21%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 44  NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR---VSLGXXXXXX 100
           NY+ L   +   R   YY+I + IP+ +I  IS + F+   +    R   ++LG      
Sbjct: 224 NYTLLEFRLTIQRKPLYYIINLIIPTSIITFISIIGFFSTSSINEPREEKITLGFTTLLS 283

Query: 101 XXXXXXXXNAALPKI-SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 148
                   +  +P   S++  I ++  +  +++  S +  + V Y+ K+
Sbjct: 284 MSILIFMVSDKMPSTSSFIPLIGLFYTSMILLISFSTICSSVVIYVQKQ 332


>UniRef50_UPI00006CC8B0 Cluster: hypothetical protein
           TTHERM_00290740; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00290740 - Tetrahymena
           thermophila SB210
          Length = 679

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 113 PKISYVKSIDVYLGTCF-VMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVE 165
           PK  + KS+  +L  C        +L  ATVG+  K I++ KQR  AVQK+  +
Sbjct: 336 PKKDFQKSLYSFLLACQDFRDLQIILAKATVGFWKKSIELEKQRSKAVQKIVTD 389


>UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG10413 - Caenorhabditis
           briggsae
          Length = 366

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 19/95 (20%), Positives = 43/95 (45%)

Query: 53  QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGXXXXXXXXXXXXXXNAAL 112
           +F R+ G+Y+  + +P+  I  +S  + ++N      ++++G               A L
Sbjct: 248 RFQRNPGFYVALVMVPAFFINFLSIFALFVNVENLSEKITVGLTNIMAMTFILVILAADL 307

Query: 113 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 147
           PK + +  + +Y+    V+V  S+     + Y+ K
Sbjct: 308 PKTARIPLLAIYVIVGLVIVMTSIGICLLIPYIRK 342


>UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides thetaiotaomicron|Rep: Putative
           uncharacterized protein - Bacteroides thetaiotaomicron
          Length = 537

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 15/49 (30%), Positives = 27/49 (55%)

Query: 11  GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMG 59
           G + VG+   + +P+ K  GH+   + I+ T+  Y   A E+ F+R+ G
Sbjct: 324 GQDYVGMRRGIVIPELKTTGHKYSGVNIAPTSPLYWMNAAEVAFLRAEG 372


>UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep:
           Slr0882 protein - Synechocystis sp. (strain PCC 6803)
          Length = 394

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 21  VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFV--RSMGYYLIQIYIPSGLI-VIISW 77
           + +P+F VL      +  SL    YSRL+ + + +  RS+G  + ++ +P+ L  ++++ 
Sbjct: 75  LKMPEFVVLAFPMSMLLASLMA--YSRLSSDSELIALRSIGVSIYRLVVPALLFGIVVTG 132

Query: 78  VSFWLNRNATPA 89
           ++F  N   TPA
Sbjct: 133 IAFVFNDRITPA 144


>UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-type
           des-2 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
           receptor subunit alpha-type des-2 precursor -
           Caenorhabditis elegans
          Length = 548

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 5/87 (5%)

Query: 13  NSVGVSSEVSLPQFKVLGHRQRAMEISLTT--GNYSRLACEIQFVRSMGYYLIQIYIPSG 70
           + +G S+ +    + +L  + +  E+       NY+ L   +   R   +YL+ + IP+ 
Sbjct: 191 DKIGTSNYLENEGWYILQTKIKRQEVKYACCPNNYTLLQLTLYLRRKPLFYLVNLIIPTS 250

Query: 71  LIVIISWVSFWLNRNATPAR---VSLG 94
           +I +I+ V F+   +A+  R   VSLG
Sbjct: 251 IITLIAIVGFFTTSSASGMREEKVSLG 277


>UniRef50_Q70Z44 Cluster: 5-hydroxytryptamine receptor 3 family
           member D; n=7; Eutheria|Rep: 5-hydroxytryptamine
           receptor 3 family member D - Homo sapiens (Human)
          Length = 454

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 14/60 (23%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 25  QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM--GYYLIQIYIPSGLIVIISWVSFWL 82
           ++ +LG ++R +++++ T  Y +    +   R      Y++   +PSG+++ I  +SF+L
Sbjct: 194 EWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYL 253


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.323    0.136    0.405 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 240,135,259
Number of Sequences: 1657284
Number of extensions: 7638760
Number of successful extensions: 15112
Number of sequences better than 10.0: 149
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 14946
Number of HSP's gapped (non-prelim): 154
length of query: 269
length of database: 575,637,011
effective HSP length: 99
effective length of query: 170
effective length of database: 411,565,895
effective search space: 69966202150
effective search space used: 69966202150
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 72 (33.1 bits)

- SilkBase 1999-2023 -